<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4Z2</accession>
    <name>A0AAD8U4Z2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_644745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000273">
        <property type="protein sequence ID" value="KAK1703870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357358.1">
        <property type="nucleotide sequence ID" value="XM_060509779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4Z2"/>
    <dbReference type="GeneID" id="85393678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF56">
        <property type="entry name" value="GALACTOSE OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042081742" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="44"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="67"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1703870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="827" mass="87710" checksum="853CD36A10634E0B" modified="2024-05-29" version="1">MMRPFFRVTACQLTRLANTDTMGRTTLSHLLLISLSLTQASRAQLSSCPSTAENIVTPDGSATYSVCQQTDYRGTTTKFVDTVATLFDCAQACSQDAQCTQAVYDKANFGCHLKAKDGLNWAADTKFTTIKLVSKLTKGVAIQSCPTIATNVTATGSTLATCPNTDYQGDTIRAVGGIASLQACALECGQASDCSRAVFQKLTSQCYIKADPKALQWTYQPGFDSVSKISVLADGVGINSCPSGYANITTQNGASFATCKNADFTVPSVNVVGGVASVAACAESCTMNQNCAYAVYDAQNQVCHIKGTVTAASDWKFNRQFTSLQMIKASTSKATSKIGRWSDVIQFPIIPVAVYVVPAQPSSARLLVFSSWGVRAFSGPTGITQFADYNFLTGAVSQRTVTNTKHDMFCPGISSLASGKIVITGGENAEAVSVYDPATNQFTRAADMVIARGYQTSATLSDGRIFTIGGSFTGPQGDKTGEVYDPAKNKWTLLQGTDPTPLLTTDHEGIWRTDNHAWLYGWRNGSVFQAGPSKAMNWYRTNGAGSVSAAGVRTTAMDQMCGVNVMYDIGKILTAGGSQDYTDSDATKAAHLISITDPGVPATVEKLPDMNFARGFANAVVLPDGKVVVTGGQPRSLVFTDTDGVLVPELWDPKTRAWTPMAPAAVPRNYHSVSILLPDGTVFVGGGGMCPAAQGSDLSWCDRAKDHFDGEVFTPPYLFTATGELAVRPVISSLSQTTVKVGSSITVALESGLNGASFALVRMGSATHSINSDQRRVPLTDVTKSGESKYTLRLPNDSGVLIPGPWYLFALSKEGVPSMARTVFIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5R9</accession>
    <name>A0AAD8U5R9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Family 20 glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357931.1">
        <property type="nucleotide sequence ID" value="XM_060515019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5R9"/>
    <dbReference type="GeneID" id="85398917"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000003">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000131">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1706931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1004" mass="111783" checksum="0E2CC9AD1DD4FAB8" modified="2024-05-29" version="1">MEQNSPAPESTGVNPVPVNPANPVLRSIALSDAVTPGIHQHTYNSADSSRAQSPSGSSYFPPSNYTTHDSHHHHETTSSSSQQLHTSGSTSSSNNITSNPTSSPANTAASNTARVPPSPGPGDILKRMTLAAMGRRESLSQIRSANPDLQLSGNIISATFNIPHSLKYRKGSDWELKARRGQSALFDSFTYLSSDETPWNHTVVAWTGEIDTPQDVLSPPGTPPATTVHFSSLNTLSAPVPIDGDARLPTPPPSEGLWLPKEDQARLETQLAHSKTIKTVPVWLCDDDEQQEAGILLKDQSRWRRYAEHDLYTLFHYKQHEPTDGRKERLQWADYYRMNQKFANRIIDLYKPGDIVIVHDYYLMLLPSMLRQRVPNMNISFFLHSPFPSSEFLRCLPRRKEVLEGVLGSNLVGFQSYSYSRHFSSCCTRVLGFPSDSGGVDAYGARVQVGVFPIGINADKCEMYAWTDAVTEKYDALKKLYEGKKIIVGRDRLDSVRGVAQKLQAFERFLEMYPDWREKVVLIQVTSPTSIEEEKDDDGSESRIATRVNELVMRINGMYGSLGFSPVQHYPQYLSQDEYFALLRAADIGLITSVRDGMNTTSMEYVICQREGHGPLILSEFSGTAGSLKDAIHINPWDLSGVAVEINNALTMTPEKRMNMQANLYNHVTTRNVQSWIDNFIRKHVHVLGTQKNVAATPLLDRATLLKTYRDAGKRLFMFDYDGTLTPIVREPSAAVPSERVLQTLKALASDEQNAVWIISGRDQEFLTQHLGHIAGLGFSAEHGSFMKNPGSDEWVNLADEFDMGWQAEVMACFQSFTDRVPGSFVERKRCALTWHYRLADPEQGIHMARECQKELESTVAQKWDVEVMAGKANLEVRPTFINKGEIAKRLVHTYNSAPASEKHPGPVEFVLCLGDDFTDEDMFRALNGLSGTEVQHEHIFTVTVGASTKVTLARWHLLEPEDVVECVALLAGVGLGGEAHEHFGQVNLAALSTVEGHIPESEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6G5</accession>
    <name>A0AAD8U6G5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_645077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000292">
        <property type="protein sequence ID" value="KAK1703093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357228.1">
        <property type="nucleotide sequence ID" value="XM_060509813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6G5"/>
    <dbReference type="GeneID" id="85393712"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1703093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="22200" checksum="B510BF388C25C2CF" modified="2024-05-29" version="1">MALELFILSCVRSPAGPLHLPDIERPLRIRIEGPRESIEKLSPSVVWDTRVFDGKFPQEAGPPLATLTFRHIYGESVRPDVPGDLVVRDEYIGRIVQDKRIVDDFDYYGVTFDYLVPVDDADPEVLQLNIIEVESDQGKTANEYVRFPVDALEYAGKKVLAVPRCCQKRKGITDRARVNNGVLVRDGHPNPWMQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8M4</accession>
    <name>A0AAD8U8M4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_645587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000346">
        <property type="protein sequence ID" value="KAK1701662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357037.1">
        <property type="nucleotide sequence ID" value="XM_060509863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8M4"/>
    <dbReference type="GeneID" id="85393762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1701662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14856" checksum="6FD50A57C8DC4BC3" modified="2024-05-29" version="1">MQEPQNSATPADDPTSEYGDDHSEHSSLASLRSSILEHQAENGRTYHSMSSGKYSFPNDEPENDRLDLQHRIWLLQLEEQLALCPAHKTAKRVLDMGTGTGIWAIDFADKFLHAEVIGVDLSPIQPEWCVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8R0</accession>
    <name>A0AAD8U8R0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_595312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000283">
        <property type="protein sequence ID" value="KAK1703430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357286.1">
        <property type="nucleotide sequence ID" value="XM_060506783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8R0"/>
    <dbReference type="GeneID" id="85390682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="125"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1703430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="52633" checksum="E462043E73E146EE" modified="2024-05-29" version="1">MAPSLIDSYGYKFRQTELHISAEQLDPLKHKFDEVGSEALAALDGMFPPPPPRAGWYAKGKQEDPQPDRDTYALLRDHCEKDPRLMKLWAEVNAVPEWVDWGQIKRGQDVFYRYAPAAVTGFAFQGLLATTGASYRPAETLVRTGGHSAKVAKNRLFETFQLLLQVTKSLDDIKPGGEGFASAVRVRLLHAAVRGRILKLNTQRPGYFDIDKYGVPINELDSMQSVCAFSTNLVWLALPRQGIYVRHQETLDYLALWRWVGYVLGTPHWILETPERALASMESLLKACLAPSKNSRALANNLVIALDGVAPIYEPKEFFEAGTRFINGDEMCDDVGLGKPGLYWDAVIRGIIWTLMVITYISRSIPAWDRWQIKTFRALFWDYIVENKDTLKGGYKYEFKYVPHHDAKTGAETADGPRPANGVGNLEVFGLVGFSIAMLLATGLLTTVAKLGFSYMASNPLQAIAASSPLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8T3</accession>
    <name>A0AAD8U8T3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_657644</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358153.1">
        <property type="nucleotide sequence ID" value="XM_060510976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8T3"/>
    <dbReference type="GeneID" id="85394875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF29">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="400"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1707937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="591" mass="66732" checksum="0E1F7D0AD84B848A" modified="2024-05-29" version="1">MGRTSYRWTRVRSIVLTLIAITCVIYILDTTWLHPRTETAMLERFMNTESLVRQPATPKSSFDWSAVDLKYPPQDPLTRVPNGGRGSLPRVQHRFASESLSASRRREARRQEVRRLFQKNWANYKEYAWMKDALNPISATAKDQFSGWAATLVDSLDVLWIMGLKPEFEEAVAAVAKIDFSISTSDRVNTFETNIRYLGGLMAAYDLSGRRVLLDKATELGDLLYGAFNTEHRMPVDFINFNDAKSGKGLIVEGSVVSASPGTLSLEMTRLSQLTGNPKYYDAAAKVMDLFHDGQQKTKLPGMWPMFVHMADRDVVTGSTFTIGGCADSLYEYLPKMIALLNGAEPKYRTMTENFLKAANESLFFRPMLPGGENVLISGNVDVDAGGNHSLDPESEHLSCFIGGIYALAGRVLGKEEWVAVGAKLTLGCYYAYQAMPTGMMPERYNMVKCDRRDACAWDEDKWDAARKLKTDYKEHLPKGFTTAKDPRYILRPEAIESVFVLYRITGDQGFQEAAWEMWKAVSNGTLVEHGNAAVLDVTQKQDPLPKEDYMESFWLAETLKYFYLVFSPPDLISLDDYVLNTEAHPFRRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAE0</accession>
    <name>A0AAD8UAE0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_723683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359342.1">
        <property type="nucleotide sequence ID" value="XM_060512589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAE0"/>
    <dbReference type="GeneID" id="85396487"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="27528" checksum="750085C6746DEA68" modified="2024-05-29" version="1">MHRLLGLHQRPAPPPKHLSTRSRKSIGLLRQAVRNRRKILTSLQERAELVRIPNVAASNETKTAEYSSSPSSGNQSSGDTFQSKHADTPMHHAAASADHQRIDIVRLIGHRVSRRDRSQIELCVLRPNHAKSWQPEREVQSNAPDEWLAYTSSVEHRACLGEHQRDKWHILAIHSHWIVLSIKGRRKGRKVMFRVSWEGSPETTSITERSARLRSSAMVAEYWHHWGGRDIALLDADIREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAE7</accession>
    <name>A0AAD8UAE7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Endoglucanase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_768855</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000200">
        <property type="protein sequence ID" value="KAK1708182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358214.1">
        <property type="nucleotide sequence ID" value="XM_060515318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAE7"/>
    <dbReference type="GeneID" id="85399216"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000152">
        <property type="entry name" value="Extracellular endoglucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005102">
        <property type="entry name" value="Carbo-bd_X2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016282">
        <property type="entry name" value="Glyco_hydro_5_endoGlcnase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF41">
        <property type="entry name" value="ENDOGLUCANASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03442">
        <property type="entry name" value="CBM_X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001043">
        <property type="entry name" value="Endoglucanase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102710" evidence="10">
        <location>
            <begin position="20"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="11">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1708182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="610" mass="65665" checksum="8AEF950AB75B9E4C" modified="2024-05-29" version="1">MRSDISLAVLLALAQTIFAQQTPYGQCGGSGWTGPTTCTAGWHCEKANDCRSLSSSASAAPTACSGSFSDISGADYVKAMSPGWNLGNTLDAIPNEGSWNNPPVVEKTFDDVKAAGFKSVRIPVTYSDHFTGAAPNYTVDAAWLQRVSDVVDMATARGLYVLTNVHHDSWNWADVTKPTSDADIQTLNDKFYNLWLQIGRKLACKPNLISFESINEPPATTADHGARINTLNDLFLKALADSGGFNTRRVVNLVGGGMDATKTTQWFKAPASIKNPWVLHYHVYSPYDFIFSAWGKTIWGSDADKAAMRNEMAIVRGNFTDVPLVIGEFDASPLNTEPAARWKWTDEFVRTAAELNTAVVIWDNGLDHLDRNAHTWRDPTSLAILNTAVKGTKNSLPDSTTDASATTQSSSAYVWNKVGTAPADQTLPWLFNGNTLQSVKTSTGTTLAANTDYTTSASSITFKAAFLSKYLSATAAPGSKANLTLAFSAGATSQVELVQWDVPVASATSSKAVAGADLKIPVTYKGLKTVAAVKALRSDGVYLFDDWTQYLGPLQQARITFNGQWNYDGGNIILPSATVQAVVSAGKATTFTFEFYPRVPGNNITYALNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAQ3</accession>
    <name>A0AAD8UAQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_642664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000205">
        <property type="protein sequence ID" value="KAK1707735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358113.1">
        <property type="nucleotide sequence ID" value="XM_060509630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAQ3"/>
    <dbReference type="GeneID" id="85393529"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF37">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="16"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1707735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="50224" checksum="E28E5F1D369232A8" modified="2024-05-29" version="1">MSFYFFNKMDQSKPSYLIVGAGVFGVSTAYHLIKKYPDASVTLVDKDAFDADERVAASWDWNKVVRADYDDFTYCQLALEAQDTFKNDPLWQPYFHQTGVYWICRSDYAQNVIDHHKKLGRKDDIIALPIAEARKLYNGLFEDADYSGAKEVLVNRASGWAAAGDCLRAVTRECIKLGVKYVTAETASLEFDERGNCTGIKTTAGEILTAEHTILSTGAYTPKLLELSAAKSGLSNLRAGDRILAAGITTGMAELDEEEYKKYADMPVGFQGYTGHGKPFIGSIPPTKDRELKWWGSKIFSNTKEILPGRHVSAPPPARDYSQWKVSRQLKEDIVEQRNLWYGKKSADWKMTKHRICWDAFTTSSDFIISPHSAAKGLYLATCGSFHGFKFFPVLGKYVIQMLEDSLSPELKTRWAWDRERPDHLQNPEYPNSELIDLVDPVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC26</accession>
    <name>A0AAD8UC26_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_590922</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359040.1">
        <property type="nucleotide sequence ID" value="XM_060506380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC26"/>
    <dbReference type="GeneID" id="85390279"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47840">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="743" mass="83166" checksum="31B1EC8B44B99D3D" modified="2024-05-29" version="1">MPPVAEESAPKKRKIRKGTTSCWECKRRKIRCQYSDQSHDICIGCQRRGTACRTQEYDDDALEQNRVAGKQQETEETLRRAETLLEQMTQVVSLLTPGAERLFQNRDASRSASEQAPRRSESTQPEPPSRSLAATPCLSIQFDNEDYLLQNNLLKANESIDGEHLELSRTIHALLPSQRDADSIISAGHNAAFLQFFTLPYKDIFLGRIRPASILSSIPSSSSHPILLARTLLYLANGLQNLPASTPETNHLDLECCAEDAMQKYLSGASSVTRNDQLTGSQEALECLILETVFHTNAGNLRCAWMVLRRAIGLAQLMGLHHDQPDKLMTLDPQTKASTSVMWHRILSQERYLALMLGLPATILDDPYAAKHKFTPEESPCDYLERRHSQIMRCITTRNESIQLEDYGVTQQIDQMLQTAAQEMPADWWLVPNTRLRQRPAITSEGEKLETILRILFQITHFNLLILLHFPYMLRSICHANHEYSRAARSNASRELLSRYIKFRCANEISFCCRAIDFSAFTACLSLLLAYIERWNHDSDVVDFLVHQRASDRALVEEVTELMLEVDHSNSSSALKQTVSIVKALLGMEADAASPSGKSSESPSADSSGDACRTSRCLRIKVPALGTINITRHGMSLISGQSACSTANKYVESGNGAFDTIGGVEQAHEERLHLQEHANLRNEGLQHTSHYTNFPTFGSGVDEIDWSWQDAGSILLGPTSGELTDPTRGPQVNCLRNDFFFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC60</accession>
    <name>A0AAD8UC60_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_593151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000207">
        <property type="protein sequence ID" value="KAK1707548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358085.1">
        <property type="nucleotide sequence ID" value="XM_060506599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC60"/>
    <dbReference type="GeneID" id="85390498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF70">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1707548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="56799" checksum="5BC68D35D5F40227" modified="2024-05-29" version="1">MSDSIEAPAAAADTASGHEVALKGQVADEGYDIFEEGIAHSVPQDIADAVRRKIDRHLLVLMCLLYGLNYVDKVAMGWAVLFNFRKDLGLVGDEYSWASSMFYFGYLAAQYPANYLLQRYKTVRILSSAVIIWGVLMLAHLGLRNFAGLMVVRFLLGVAESVVTPGILLYTSIWYTRKEQVLRTMLWAAMQGAFSIVCSLLSFGLGHITNTALRPWMYIFLVLGILSILVGILWIIFMPETPNKAKFLTHEEQVIAVQRVAQNMTGIKGYEWKYYQMWHAVIDVKTWLVLAFVLFTQLPNGGLTSFGSLVISGFGFDAFRTLLIGLPSSIVSAGSMIIWGTISIHYGNLRTWGMIIPLLPAIAGIAAVYATMDTGANKYGRVVAYWLINSYAVTWPFVLTIVGQNVAGHTKRAFTNTMLLMVFAAGNIAGPFFFRSQDAPKYVLAIAVILVCFCAALLTAIILRLYMAWQNRRRDSKYGNADGVEEKVDGMRLGMHDKTDLENLDFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC74</accession>
    <name>A0AAD8UC74_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_636157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360148.1">
        <property type="nucleotide sequence ID" value="XM_060509234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC74"/>
    <dbReference type="GeneID" id="85393133"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1715005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="128" mass="14196" checksum="5A8C077F159F9A83" modified="2024-05-29" version="1">MKKTKSPWSFISMLPSRYWCTVVLCLSSIPATALIQIPSSRQRATSSDLLLRRHKFAENRNPEFDSGESNVIWSIPRCCVSADPVAMISWHEHRRISSSVKTCSSPITASSPGRSGWTGDLGCRLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCI3</accession>
    <name>A0AAD8UCI3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_765079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000152">
        <property type="protein sequence ID" value="KAK1711971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359295.1">
        <property type="nucleotide sequence ID" value="XM_060515239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCI3"/>
    <dbReference type="GeneID" id="85399137"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="516" mass="58791" checksum="056B37CF19E3BD20" modified="2024-05-29" version="1">MVKPRLIILIRHAQSEGNKNRDIHQTIPDHRVKLTQDGWQQAYEAGRNLRKLLRADDTLHFFTSPYRRTRETTEGILSTLTSDEEDPSPFKRSNIKVYEEPRLREQDFGNFQPCSAEMERMWQERADYGHFFYRIPNGESAADAYDRVSGFNESLWRQFGENDFASVCVLGMSDTSEPFGLVSLTFLVTHGLMSRVFLMKWYHFTVEYFEDLRNVNHCEFLIMRKQEESGKYILENKLRTWSELRKERAELKEKEEKERSEVEGNQERSTKDAKNGTLLERSKTFIVTRRWGGCPNGCNHKSHYQRRDDLEALRRTDEVTSNGSVVSRRQSPAPGRRPIKRCEQGYTSDEGTDSDGRPPQIDVTRARHEVVSSPDGTPSFISAEDRLRSMISPHLNVGRDFGGTFSGQTSIAGSDTDSSEEDGHRPEITAVTKIKVGIVSNGDNTGANGSINSIVGGQTKGNMTPNTEDEQSDEKSRRRRANRLGDTNSSHRGSEADEDDIDAAEKRDRSILGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCK6</accession>
    <name>A0AAD8UCK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_44162</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360542.1">
        <property type="nucleotide sequence ID" value="XM_060503112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCK6"/>
    <dbReference type="GeneID" id="85387011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF13">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="557" mass="60177" checksum="46C707D17E2194C4" modified="2024-05-29" version="1">MAADADERTPLLKVKSGAGAVKRVGRGLWSPANRILFAGFLVSLTLGLTQVPIIYVFRVMACETFYKSHAPYDGPLSEMCHRREIDANTATQVSILGMTTSVCGILNLFICGDLIKRWGTRWALISQTGLLGIRVSCQVLAVSQGAQKGIDMMQYTQLIGIFGGPRGYMLVLNTAIAEVVERRKHTGVFGRLQGAVMIGTAIGYLLGGVLGDVFGITSPFVVAIGCFAFATTYGAIFWPAPPEETEETDGKTTLGASGFLAPIKVLMPSKYRLESGKIVKNYGLVFLALGIFFGVFATGYAPILIQMYATSRFNFGTTENGILMSGNSWIRGIFLMFIFPEIIDSGRRWFASSSHAGALQKTLTQEERSVIPTHPEDMDPAPGLMNASEPTKAPPEEEDEDSTFDLFFLRWSLVVDGIVTSLAAWATEGWHVYAAAFLLPFASGSAPAAKGVITEMCPPHMRQDALSAITLVESAATLTTQGIFGFIFATLSEMGKPNLTFFVNAALAVVAVGILLLAHYPPVNSTRVEGEAIEEIGESNRDMNECRNLAEVTHRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD11</accession>
    <name>A0AAD8UD11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359534.1">
        <property type="nucleotide sequence ID" value="XM_060514820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD11"/>
    <dbReference type="GeneID" id="85398718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042039992" evidence="1">
        <location>
            <begin position="18"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8486" checksum="FE607EC2EB9DE27A" modified="2024-05-29" version="1">MKVYAIALLLSSSLATAEIARVVCQQPPREWGNGNCNGDDTWACGQRCGRCIDENDQHGYAGFWRSSDNKCDCYCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD51</accession>
    <name>A0AAD8UD51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_634622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360673.1">
        <property type="nucleotide sequence ID" value="XM_060509112.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85393011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="651"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="838"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1380" mass="154447" checksum="940FFC15761DB6FF" modified="2024-05-29" version="1">MEYNRSPSFGLGARANRRASTQSTIDEEGRKPLFSKPSRESLEPQNPSPAAAGSNRFGYSPTNVQTSATGRPPSRAAIPRPSSSLSQTPSLNSNHSIEIVSPGSRIPRPKSTIGIFAKGSGVSVAEAWKLADENRVQTLEKARRATPAAIDASPSPAPRPYTNRQVSDESKSRRSLGKDAVDYSRPRPLSRMSSDSLRDTYVGRYGGSPGSNSLSSSGSFDRRLSQYEREMAESPSASRDQDHFFGKTRVGPKIAETGHTLARRTSNSSLNGSQSVNRRASNGSLNGGPGLGRRTSYGSLSASPRPGAFAKSHVPEGHIKELLEQDEKGIKRSARPKPDDEVAADTPLPSVETSRLPQEPTPPTSRPASTNPDYRSPDKSYAWQLDADFTAGDLQISDSPRIRTGGAGFSEASDRRSSYGSAYAEEQLLGLNGNLRRESPLGPSPRAGRSNTRIDEIRQREEKAKEELAESRKALPRARNNTRLEEIREREAEAEEQLAKLPRRSYYPTPDDLPDREEVDTQAPPKNTKLDEIRAREAESLSKKAIATSRLEDIREQNSMMSRSMSPEGRRSGDFARESTPIREAAAESVWPTEDGEHIANTPVTIYRNSPVRERNKSLSESPASRNERASPKPARPLGAHARTDSRDLLQRLARAASSSPAPETNSQPVAIDEKKGPSIEDLEKERLERANRERERLEKERLNREKLEKERLEREKLDREKLEKERLEREKIETDRLEKEQLAKEKDEKEKLEKEKVEKEKLDEEKREQLKLEMERLEKETSKETSQRAETQRRRSEARRSAPEHEPESNSPPRRNRRETIKVSEAASTETKETYDSKSSSTDQLNAPKTGRPKSRVDFAARRRERRQKSTDSAKDNRKSVALSDGGDPTDRIEQEMKLFAPADNQSERGSRAPSAEPATEDEDKDLAGETPRPKKVDPLSLPTPRVTGAYVETPATVKVERIEENTLPPLKRPDPSSNATFDRPQSRRGSRPLSRAGTFFKATESGSETSDQKETGGTSTTSSLRRRNRSTSRPRKPLTNSVKPPTVKDDIKELQRIHQIEDSTLDDFEELFNRQKLQNDPDLDIESMLDDIAVKKEEVAAKPNIPTSQRNHELEQYDRMSKTLKDGLFNIRTAKQGIERLEGQVSHAEGGKHDDAATLEKLSEKQPLAKGPHHRHNPDHARDCPDCVRQTPIKEVSYLHLPVPSLYRRNPFRLTFLGLVLLLVSLWYAVESAMCEAYCRPTSCSSTPCVWSPTDPTWGVAIPVKLDEWATGGLGRQLANQYSEEASDLWADALDFVTGTDITTIDINTLDFYDKRQLRRRLRKRGLAKRTVVESASDRAKWDAWHATRVASERAQDAREMGYDIGDADESLGDDEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDP1</accession>
    <name>A0AAD8UDP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_682153</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359494.1">
        <property type="nucleotide sequence ID" value="XM_060511219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDP1"/>
    <dbReference type="GeneID" id="85395118"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010573">
        <property type="entry name" value="MFS_Str1/Tri12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06609">
        <property type="entry name" value="TRI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1712637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="608" mass="65515" checksum="DDA8CEA59A8D807A" modified="2024-05-29" version="1">MGRDREMKIRMAQEAKAVIEFEEDPHRAALEDNPSEAKVGIKTWIAIFSMALSFGPCVGLAFLTVAAVVVQIATEFGGQDQLAWLVGAWSLSTACSFSLAGPLSDVFGRRMLVIGGQVTVVIGSIAAVAAQNIGTLIAAETLIGIGTGFVFVSYAGVPEMLPNKWRSLGLGILESGIAVPWGILSVLLGNAFFKYASWRWIFGLSIIIEVISIVGTWFSYHPTPRPRGDFDKTRMQQLRDVDWIGLFLFTAGLAVALIGLTWGGTPAYPWNSAGAIAPIVIGFAVLAVGFAYDFKVAAHPMFPLKLFVMFRRYSVLLVVLFVSGMNFNSMSALLPQGFLYMFTTDGIEIGALSLPNTLMIGFTGVLAPLIAHKVGYIKWQLVIGMAFQALFIGASAATVYPNHKFAYAFVPAFGVPMFVWVTILSYAVASLHVPHSNLGVAMGLLGTFRSGGGAVGNAIFNTIFQEKFREFAGEEIANAAISNGLNPSDLGIIIPAAIEFNLGNPRALVNVPGITPEIQDALREAVREGAGHALKIVFYITIPFSVIALICSLFIEDPTAYMTNHIQSAMGQEMAQNRGKRATTPEEGQAIEFETVRTVHSEQIVVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEE3</accession>
    <name>A0AAD8UEE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360209.1">
        <property type="nucleotide sequence ID" value="XM_060509215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEE3"/>
    <dbReference type="GeneID" id="85393114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="9552" checksum="944E012265C395E2" modified="2024-05-29" version="1" fragment="single">MPFLPSTPEPKTHSFSSSCTPTGTGEKEDMSRGAREDDGASVGWSISRSASTRHDTAGAISLLSRSLVLYTACCRPWIIRWSHVALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFH6</accession>
    <name>A0AAD8UFH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate decarboxylase family bicupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_754784</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361997.1">
        <property type="nucleotide sequence ID" value="XM_060514528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFH6"/>
    <dbReference type="GeneID" id="85398426"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041935120" evidence="5">
        <location>
            <begin position="22"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="154"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="331"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="503" mass="54469" checksum="8061BE8460B151FE" modified="2024-05-29" version="1">MYTHGAFLLASLLAALPQSYAIPAPQMGDYGENKGPVGGVDPPIPTVTTPTGSLRGDSSLLGGNAARPDPETGGSANVDDVTLVPGQEADGKLGLYLNFDGVDVPQPIRGGLGSPDPGPRTYDYEKLNPDLFAPPGTDKGDVENAMWPLGLSHNRLGSQEGAGWARQQNTKVLPVASAMAGVDMKLQPNAYRELHWHTSAEWALMLKGCCRIAAMNEDGKSFVDDVCEGDVWFFPKGVPHSIQAFDQGTEFLLVFDQGSFSEENTFLASELFLRNPLSVLSKNLKTDVSAFDKIPKDQLYIFNGTPAPKDIEQQNQTSSAGSLTGAESYTYHWSQQKPFQVPGGSVKILDPQTFPIAENFSAALVVVQPGAMREIHWHTTSDEWNYFLQGSGRITIFEAPEASRTFDFTAGDVGYVKVGDSHYIENTGTEDVIFLEVLQAPKFSDISVAQWLALTPKQVVKDTLGLSDEVIAAIPKEKEYIKVGNTNMTALADGGRNFKKFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH33</accession>
    <name>A0AAD8UH33_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_625111</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363841.1">
        <property type="nucleotide sequence ID" value="XM_060508482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH33"/>
    <dbReference type="GeneID" id="85392381"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057654">
        <property type="entry name" value="Znf-CCCH_tandem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25542">
        <property type="entry name" value="zf-CCCH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25543">
        <property type="entry name" value="zf-CCCH_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="562" mass="61754" checksum="DDBE494339E20279" modified="2024-05-29" version="1">MPTTTHTTTTRSPFDTNNLGINTNNSAPVLPPYLRTSSQSPLHSFPFSPSSTLPSAIGTGIKKEKSSTKMALDNSEIMDFVTRYQNLQGYQNASDQLMKDLLIYCKEIQGQYADENQMLKQELRNAKLDLEHATTSRREMQQVLQELDYDNSYMKNRNPYVLILIDGDGLLFQESFIRQGIEGGKQAAYALRTAVAEYVGSQSGEVEIVAKVCANLSGLGRAMRRDGCLDSESELKEFSLGFTQAKASFDFIDVGHGKERADSKIKEATRWHLRNYNCRQILLGISHDAGYAPFLDEILQDKDTRSRVSLIEGVATVRELKSTNVHILDPLPSLFRNQKLIDRSGDRAAERAEAYARCSAQAPASVPFFPAPSRASTSSPVMVASPISPPATVATTASSSWAGVTAKASPPPVITTPLAKISVNVPARKATEPKVATPAWNPGGRGMDPPIPINATAMDNIKKRTGKDKLCNNHYLRGPCAKGDECCFEHKYKPNADEINAIAHLTRLNPCTSGQECDVENCIYGHHCPSVTGTTCTHPYCKFRVEDHPPGTKFKNAKIHEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIA7</accession>
    <name>A0AAD8UIA7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_583872</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362118.1">
        <property type="nucleotide sequence ID" value="XM_060505705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIA7"/>
    <dbReference type="GeneID" id="85389604"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000064">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="72"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1721322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="49663" checksum="D20B6438CE5D6891" modified="2024-05-29" version="1">MPGESSSSSSASASSSSSSSPQNNSTLSRIRNIASHIMAPVSTTNFPASTVPQAPEDPLFGLMAAYRADQSKDKVDLGIGAYRDDNAKPWVLPVVKKADEILRNDPELNHEYAPIAGIPQFTGKANELMLGADSPAIREKRTSSVQTISGTGAVHLGALFLAKFYKGNRTVYISNPTWANHNQIFGNVGLPIAQYPYFSKETKGLDFEGLKSTLSSAPERSIVLLHACAHNPTGVDPTQEQWKEIAALMRQKNHFPFFDCAYQGFASGNLAQDAWAVRYFIEQGFELLIAQSFAKNFGLYGERAGCFHFVTAPASDAAETTKRIASQLAILQRSEISNPPLYGARVAATVLNDPALFAEWEDNLRTMSGRIIEMRKVLRAKLEELGTPGTWNHITDQIGMFSFTGLSETQVLKLREDAHVYMTKNGRISMAGLNTRNVEYFAKAVDKVVRETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ11</accession>
    <name>A0AAD8UJ11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BDZ83DRAFT_752817</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364213.1">
        <property type="nucleotide sequence ID" value="XM_060514258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ11"/>
    <dbReference type="GeneID" id="85398156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="320"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="823"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="901"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="947"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="998"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1023"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="401"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1098"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="1114"/>
            <end position="1133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK1724158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1145" mass="125857" checksum="BE54103D9C1A2919" modified="2024-05-29" version="1">MSGDYPKHPFLLTVQETAQALGVDPDKGLSSQQVQQASDKYPPNEFEVGESVPWYTILSKQLFNAMVLVLVFAMILSFAINDYIEGGVLAFVIVANVTIGFWQEYRAEKQMDALRTLSAPSANVLRDGKTKVIPNAEVVPGDIILLKMGDTVPADMRMFEAMNLSCDEQSLTGEAQPVDKTTEANIMVPGSEKKATEEGEVGIGDRLNIAYATTIVRKGRGRGIVVATGMQTEVGKIAASTQKKTRKPGRSMNYKKYGKRQPVVGLSRRVYDAVGKFLGLTEGTPLQKKLAALAYLLFGCAIILAIIVFAAHKFDVTGEVIIYAVSLGIAIIPESLVAVLTITMVVAVTVMRKSNVVVRDLSALEALGGVTNICSDKTGTLTQGAMIVRKAWLPFSHTYTVRDSQSPNDPTKGRVTHSESKEQEKVVDEAPKRDYDQERSAAVLKFDVPEEKLQNKQPAKAPEAENEAEMTPRLKAFLLSSALCNLATVRYDDEEAKWQTTGEPTEIALQIFSHRFKLGKKSLEGLGWKQLAEFPFDSSIKRMSVIYDIPENDETADIWSPENSLVFTKGAVERILDLCTHIGFGEDRQELTDALKEDVLSQMNELASQGQRVLAIGCRDWNGKFTTKQADVAQEKEDALRTEVEQGLTLLGLAGIYDPPRRETKPSIAECSSAGIKVHMLTGDHPETAKAIAKEVGIIPKNLGVLPDEVAKAVVQKATDFDKMTDAEIDAMPELPLVIARCAPDTKTRMIDALRRRNAFMAMTGDGVNDAPSLARADVGIAMGSGSDVAKSASKIVLTDDKFNSIVSAIRQGRRMFDNIQKFILHLLSSNVGEVILLCCGLAFRDGADLSVFPISPLEILWINMVTSSFPAFGLGREQAASDVMRKPPQNKKRGVFTNQIIIDMIVYGIIMGALTLATFIIVVYGANGGNLGSECNKTFTEACRPVFRARAAVFAELTWIILISAWEFKNLRRSMFRLNPDSKSKFPFFKDIYGNKFLFWAVIIGALSVFPVIYIPTLNTTLFKHIGITWEWGIVVGFTLLYVVGVEAWKFVKRTFNLLDDHQVVRGAFSQGGEDEGRDFKKTITFSSFKSWHSFGRKDTGESTGRRSRSQHRTNTNLSGDTHTADASPSNSNDEKARMAGGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ94</accession>
    <name>A0AAD8UJ94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional Coactivator p15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_576754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transcriptional coactivator PC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365427.1">
        <property type="nucleotide sequence ID" value="XM_060504947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ94"/>
    <dbReference type="GeneID" id="85388846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060261">
        <property type="term" value="P:positive regulation of transcription initiation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="entry name" value="Transcriptional Coactivator Pc4, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003173">
        <property type="entry name" value="PC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045125">
        <property type="entry name" value="Sub1/Tcp4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13215">
        <property type="entry name" value="RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02229">
        <property type="entry name" value="PC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="ssDNA-binding transcriptional regulator domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcriptional coactivator p15 (PC4) C-terminal" evidence="8">
        <location>
            <begin position="51"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="157" mass="17212" checksum="10453279710CEC71" modified="2024-05-29" version="1">MPFTKGTKRAAPRDSRSDSEDEVITKSNKKTKTAKNGASTDGVDKDGNPFWDLSNKRRIGLSQFKNTTFVNIREFYEKDGDMLPGKKGISLTVPQYEALVKAMPAISEKLRAMGHDVEDVEEDGGAPTAVEAPKTATKEKSRAKKSNIEATSDEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJD1</accession>
    <name>A0AAD8UJD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome segregation ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364393.1">
        <property type="nucleotide sequence ID" value="XM_060514240.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2079"/>
            <end position="2109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2141"/>
            <end position="2299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1313"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1961"/>
            <end position="2013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2141"/>
            <end position="2155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2176"/>
            <end position="2187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2222"/>
            <end position="2246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2270"/>
            <end position="2282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2283"/>
            <end position="2299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2299" mass="254807" checksum="15489C83A3B3B149" modified="2024-05-29" version="1">MAPVEREASRDADRPLRHRQSMSSDQGRALVPMWDSSDPDRAPPPLPMNPQSPVTTSRKGTSVAIQSAHAALNERARESAMLPAPLTKRNTETSPERSLIKGSHHKRMQSLQPGNVRDLSLLLESGQQSNPPSPTKSPERTRPSTPAANRRDSFADTRRDSFADSRRDSFADLRSTEREATTPSSVQSQTPVVRPTMKRQQQSILGENTPPQSATMLAIQNMPLQGQQDKENVANGSTALVKAPQQVEALSGQILSLTSIATALQKDMAQLSRRSRDNATDLLSLKEATKARDEDIRKSLRELINNAQDAAASSRPSSRDPFVNSLFLDTKPHHTSPPPSKAGRPFSLPRIPSPNSFAASIDREALSTPSLCNSNANSNSDSPTTIAILDKIIRDMGTKEGHDLLLARLTDVAEKLAGVAPASKVEELIQLVKTKPADAMISRSGGGHGESNRNMPRAAVFDDDNSTMDFDYDPGYASQLTHRSERALHNEPASRSAASGNASEIVSDEVLKIIRTVKDSVAQGGGLTAEVKALVRELRGEVLGMGREIGRRLDEAQAQPKSEEPLTDNDEVSKIVHEGIEQMRENMDELLREHRRQSANSVASRAPAIDYQEIYNAMRAALRDSQASQEKEPDLNREDVIEAVRDAWENYKPEVENQDPGLGREEILEYLKEGLQDYVDRDQEPVGASREEVFQAVVEGLKHFSPPRVETPTSLSRDEILEAVRECLEEFEFPVAPSAFTQELTREDMLHAVKEGLSGYDLPTAGALVPHQNNNEEVVTRLQEILEYMRGEFRAVTEDAKVNAAANGRDTEQILDATKDGLEKLRADMEAYVSHLSGSTAGQEEITQTLLGTLDTFRDEMAMLVDRVSSDSRSTIESHMESLRDTVNSSMVPVTPQVNQKEIIEAVRDGIDSVRGELRRPFAGVTDILDALHDGLADLRISIDKVANRPADLTANDEVLDALKAGLDNVRSEIDGLRELQGQNDKALTTMHDGAVVPVPADALKQDDIKNLEVLITQLRIKIEAMEPANADPVAKDDLTRMEDMLRSLQESASKDDMLRLEDMLRLVQESVSKDETSRIEEVLLNAQSSVTKEDITRLEEAILPIQEWVKSKESPVSTDASTKEDVQAIETILRNTKGRLDDLIDNEQAVRKEHLDSLENTILETREAINLITTQLDTLPKKDDVTSVEALVTQVAAGFEEMKESAAKQLEDPERVTKTDVEAVEAACHDIKDVFDQLLKTEIATLVTKEDLKKTETTLEELKGPLEALVVLEGLKEGLQEGIKAPLDELKTELKAPIEELKAPIEELKAPIEELKTPLEELKTRLNALTESHDKGTEERQAEIVGVGERVTEVKTFLEEFQGLVKGKLEEGATGVESLSKLLEGVSTAVENNASVNQDLKDLSDTMKLEFEESKAAVVGAKLESDEKFQQTTDALSAKIEEKVTELMTKYDEFHVALDDRAKAGEARDASTEEAVLGTKAVAEELKSLVDTLGAAVTDSMEKMEEASKTVFTRVEDLMTKSEENHTDGKADHQQTRDHLKQAVDAVEIIQGQLVESQPQILESIKDVLLIVGQHYDYAKTSTNDIQKTIEDAKPVELALPPIPDKYDDTVVLEKLAKLIEHSEAPVEKYDDAGVHEKLDKLVEHASVPPEKYDDAPVHEKLDKIVEHVSTPAEKYDDTPVHEKLDKLVEHSQVPVEKYDDAGVHEKLDKLSEQQLLIPTEKYDDAPVHEKLDKLVEHSQIPVEKYDDAPVHEKLDMLVEHSQVPVEKYDDAPVHEKLDKLSEQQLLIPTEKYDDAVIQEKLDRIAEYQSLLPTEKYDDAAVQEKLDMLACGQSLIPTEKYDDAPVHEKLDKLAEQQLLIPTEKYDDTVIREQLGVLAEQQLLIPTEKYDDAAVQDKLDKLAEQQALIPTDKYDDAAVHVKLDELVDHSHAAEKAFGQLDTLEKVHQQVIQTATDISLFLASQTKKIKEEEDDREQILQEVTIDLERKLALREQIEASLLDLKQEEERLRASVLGLRTEQESLIRQKTRLTGDVSSLETALHIRRDELHDMESRAEGLERRILEGVMDHSRVLLMSKATKGRDAMSRKRVRDQKPGQENGVPEKPASPAVNLALSAKRNLKPPSQAGTARRILSLSQITNNVPTGGVQRSQSVRTAGARGHRKSSWAGGFSKGYGDLDKENMSLKETEEENMPSPTPVMHEESAGADDPSDTETLRRSSHGSRVSRGSRGTTVVTESTDNYTGDGDYSDYYDDNHSDLQSDLQSDWTESVVSSNVSSNVSSDLGSDMSQETLNNEVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJR4</accession>
    <name>A0AAD8UJR4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_719410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365236.1">
        <property type="nucleotide sequence ID" value="XM_060512170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJR4"/>
    <dbReference type="GeneID" id="85396068"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000251">
        <property type="entry name" value="Ubiquitin ligase complex F-box protein GRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF67">
        <property type="entry name" value="SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="70"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="6">
        <location>
            <begin position="204"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="659"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="697"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="782" mass="84947" checksum="EA5AB8CFA9D63A7F" modified="2024-05-29" version="1">MRPAAPSIEIMATQSATPDSRSSSSTNSPLPADNEESDFFIAGNDSQSSLGVPNIEDMQVSDDPCQPAVNRLPSEILISIFAKLNNSNDLFNCMLTCKRWAKNSVDLLWHRPACTNWKNHSSICLTLQLETPFFAYRDFIKRLNLAAGGLADKISDGSVMPLSVCTRVERLTLTNCRNLTDQGLTKLVENSSSLLALDISGDEHITDVSIQTIAEHCKRLQGLNISGCRLITNDSMIQLAENCRFIKRLKLNDCAQLQDNAILAFAENCPNILEIDLHQCAQIGNEPITALISKGQSLRELRLAGCELIDDSAFLTLPPAKTYDHLRILDLTSCARLTDQSVQKIIDAAPRLRNLVLAKCRNITDVAVNAISKLGKNLHYLHLGHCGHITDEAVKRLVQQCNRIRYIDLGCCINLTDDSVTKLAQLPKLKRIGLVKCSSITDESVFALARANHRPRARRDAHGNIDEYYSSSLERVHLSYCTNLTLKSIIKLLNYCPRLTHLSLTGVTAFLREEFAEFCRPPPPEFTDHQRGVFCVFSGVGVTKLRDYLNTSPEYEGLRDSPGPRFPGLSSFPARRAADPRATAGHAGQTNGDVEVDEAEVPEDDEFEGLDGSEMAVDGQPLLAQNLVNGNAQNGVPPPPPNHVPPAGAVPMFAQPLGQAPLLFSPTSPSFPQSTRSPTAGGPANHPPPLVISSHYSPTSAGPSTSTANALSPQGTNLGFPAYTNRRPAPLGASTASMEASMLSPVSHRSRPASVISMEASMLGPLDPDMVEPTTPNGPQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK05</accession>
    <name>A0AAD8UK05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_718930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365817.1">
        <property type="nucleotide sequence ID" value="XM_060512125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK05"/>
    <dbReference type="GeneID" id="85396023"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000004">
        <property type="entry name" value="Cation diffusion facilitator 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF4">
        <property type="entry name" value="CDF DIVALENT METAL CATION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="287"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="504"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="573" mass="63949" checksum="DFA74D9B76994E3C" modified="2024-05-29" version="1">MSSPQDHRSSSPRVGSFKRPSVLNADSDPSLLATRGSGALVSLIRNRSNATLRESLKSPAYHQLGHDEEEHESTSLLGFLHRDSDDDHHHRSAAEERRLSELIFGPQMRSMRLIGNSNPRYQWERYWKTEAELEVMPKHIREYYERNNDLIRMYLYIDQLLDSSVPHDLLNEYHQALDASAYRPVDVPQTITEESPTPTSPPSRGGLTYGSTTASAQNSSTEQSSSANSIQQKAKRKPKDIFRSTEATPLLSGSDEEEGLADQPKPEIPWLEDSDLDSSDPIVTLAIWVNFIANAALLIGKILVVVSVPSVSVLASLVDAVLDFLSTAIVWTTTRLIAASQNDQHSYPVGRQRLEPLGVLVFSIVMVTSFCQVALEAIQRLMSPDHEIVQLGIPAISIMVGTVVIKGLCWLWCRLIKNSSVRALADDAMTDVIFNTGSILFPIVGYFAKIWWLDALGGLLLSLVVIVNWSGTSMHHVRNLTGFSATSDERNLLLYLTMRFATSIRQIQNLRAYHAGDKLFVEVDIVLNANMPLKDSHDLSEVLTYFLESVPIVDRAFVHVDYATYNVDTHITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK21</accession>
    <name>A0AAD8UK21_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361970.1">
        <property type="nucleotide sequence ID" value="XM_060514526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK21"/>
    <dbReference type="GeneID" id="85398424"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="370" mass="38555" checksum="A69B31193BD0B9D1" modified="2024-05-29" version="1">MTTTSDPNPLTTQRGAAPLTTVFTTPDFCNSLYWTNTITPPLSSVVCMPTSWHQVNDYSWGYYSPGICPMGYTEGCAFPTSLASSKDGAVGMGGPVTVGETPRLCCPTGYVCYTDTKSYGYSKCISTIPTTSFYNSDNQPTSQLALVYAVQVRWASSDLSILETDPTVPGSTYTGVTATGSGGETVATTGAQTGSNSIATATATSTPTGSSDGGGGGISVGTTIAIAVGSVAGTLVLALLAFILLWRRRKRRHAQKAAAAGENGGSADSDSKSDSVAPTMAHKAPVGKSSLDIMSPSTARPGTGTTVVGDEALHSPRSPTTTAQLDSTTVMEMETMERPQELPDTNEVFEMEGDMPGPPLYREKEGWPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK55</accession>
    <name>A0AAD8UK55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_783071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362794.1">
        <property type="nucleotide sequence ID" value="XM_060515577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK55"/>
    <dbReference type="GeneID" id="85399475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="519" mass="55355" checksum="DD190AD57BD5F12A" modified="2024-05-29" version="1">MGDSPAATSAEKPQQTNSEQNGNVQSALDRITTTASYVPPEMSPIRRRAVMCALCLTLLLSALDITIIATALPTIAATLQATASEYAWVGSAYTLSSTASTPVWAKMSDIFGRKLTIMTAAATFMAGSLIAALAGNIQVLIAGRTVQGLGGGGSLVLVTIVIGDIFKLEDRAKYYGMTGIVYGIASAVGPVLGVFINLPFDGVALIVLFFTLKVETPKEPFITGLRELDWIGFLLIIGGTICFLYGLETGAGGIVPWSSALVICLILFGVLILALFVVWEARFAKNPVIPFRIFQKVTNIASFTLACIHSFVFISYDYFLPLYFQVVLGFKPIIAGITLFPLLIPLTFMTMLGGLFTRKTGNYIIPIFFGSTLMTLGNGLFISFGINTEWAKIAVFQMITGFGAGLLFQSPMISIQTHTKQKDMAAAMSAFSFVRSLFSSMSIVIGTVLLQHNLGGGELTAGKLGSEDGNDGTLGASKTSYMSALRVMWAFFTGVSGCMLLAAIFIKPKPKKSSQSDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKY3</accession>
    <name>A0AAD8UKY3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_720476</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363674.1">
        <property type="nucleotide sequence ID" value="XM_060512278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKY3"/>
    <dbReference type="GeneID" id="85396176"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="20593" checksum="9348A1E8ACF6924A" modified="2024-05-29" version="1">MPAVIEMWVEYAIGILVLFLRIFTRCKKVVGFKWQGDDYLAVAAIIFFTLEVMMCQIIVEKGSITGMTDEIALSLTPEQYKSHETGAKWLFAAWYIYVSMIWSLKGIMLFFFSRVTKTLPEERLVKVVSVITVFAYLATLAVVTGHCRPMHKLWQVYPYAGDDCTQNTSKYYALVTTNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULL3</accession>
    <name>A0AAD8ULL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_753395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363651.1">
        <property type="nucleotide sequence ID" value="XM_060514348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULL3"/>
    <dbReference type="GeneID" id="85398246"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="16758" checksum="948B075C93BA5EC7" modified="2024-05-29" version="1">MSLPFPTSRFGPGFTVPTAVTVTEGGRTVTFTPTPTGGTTSDSSPFPDNILQQSGLAPGQIIGITVGATSGLVFFVVALVWFWNRRRARKLAARDEALDTVMEDPEKPDDAAMMMAQNTGETVELPAPRVVHEMPETREGPPVELPAPVERHEMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULS1</accession>
    <name>A0AAD8ULS1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_618932</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365743.1">
        <property type="nucleotide sequence ID" value="XM_060508094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULS1"/>
    <dbReference type="GeneID" id="85391993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000019">
        <property type="entry name" value="RNA exonuclease NEF-sp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="321"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="707" mass="77839" checksum="8D35EB2FECB0845D" modified="2024-05-29" version="1">MMGKRRRNRDEGGEGTIVASDVVPGTTSQTHETTAEAETGNGENSSRESSSNTQSSGSLKRSAPDDDDEGWTKVERSSKKRKKVPREGSNNYPAITFSTSAKLFSKINLAMLRDLVLYIFADGTGPNWVSVSHRPNFRKIVVLMVPGLEEAMFKEGVNFDNYTSGPARNQDRTETTPDDYYPRALAADQLPVALQGFAKMFPHLWPVKAPGDDKYMKLHSPMGTFLTAPMPKNKDDRKGPKPAREPSGWKNERTRITEFLASLEELETAGHLIHPALIENEERKATFKVPEGWAISKVDKLEDGEVPEAEVESGSVTAGRECLALDCEMCMTGESEYSLTRISVISWSGELIMDELVKPEKPIIDYVTRFSGITEEMLKPVTTTLKDIQQKLVELVTPRTILIGHSLESDLKALRFSHPFIVDTSLIYPHPRGPPLKASLKWLTQKYVNREIQKGGANGHNPIEDSRACLDLVRQKCEKGKLWGASDSQGENLFRRLARAGTAYKAQGGDAGGLVTGKTSAAVDWGEPSKGPGAGATYQIGCKSDADVVNGVIRAVKGDPDGLEIPGGGVDFVWGRMRELEALQGWWNKNRVESASSDGGPPPLDKTQFDGKLGGSPLEQCLARLTVSLQAIHDSLPPCTAFIVYTGSGDPREMSRLQAIHTQWKREYNTPGKKWDQLSVKWTDEEEQALRRAVIKARQSIGFIGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM16</accession>
    <name>A0AAD8UM16_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain dehydrogenase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_625274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363876.1">
        <property type="nucleotide sequence ID" value="XM_060508488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM16"/>
    <dbReference type="GeneID" id="85392387"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF7">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE (AFU_ORTHOLOGUE AFUA_2G00830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="274" mass="29511" checksum="89897B1BFFD0BD89" modified="2024-05-29" version="1">MASIFVPGNTAVITGGASGIGLAIAKKCVGHGMKVLIVDRDTKLLQAAKETLGGSSATFELDVSLLQDWEKLKTEVNTSIGGRIDLLVLNAGIGPKSSWLDTESFRKILDTNLYGVINGISSLLPLVGSGQSSKSAIVITGSKQGITNPPGNPAYNASKAAVKSLAEHLSFDLKDTPTYVHLLVPGWTFTGLAGAAPGREKPAAAWTPEEVADYLEKKMTEGLFYILCPDNEVTEEMDRKRMMWSVGDVVEGRLPLSRWRDDYKDEVQAWMAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMH5</accession>
    <name>A0AAD8UMH5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="5 16">2.7.8.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_625136</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 17">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.11" evidence="5 16"/>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363844.1">
        <property type="nucleotide sequence ID" value="XM_060508483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMH5"/>
    <dbReference type="GeneID" id="85392382"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014387">
        <property type="entry name" value="CDP_diag_ino_3_P_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000848">
        <property type="entry name" value="CDP_diag_ino_3_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 16 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1723789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="27114" checksum="92C5770D2EAD74AD" modified="2024-05-29" version="1">MPLHPRTCSLLYSVSCLLDALDGYAARAFEQSTRFGAVLDMVTDRCTTSCLLVFLSCAFPRWTIVFQMLLSLDFSSHYIHMYTTLTMAGSESSHKNVDESRSWILHLYYTNKTVLFVFCALNELFFIALYLLSFSSPLLSPSLLNSVSNSEAMQIQAGAQVNTSLLSQIFPNPYSAAALELARANKMDSFWPWVLTAISFPVMAMKQFINIVQIVKASKWLAEGDLAMRKAQGLPRKKSKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMI9</accession>
    <name>A0AAD8UMI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_793910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363155.1">
        <property type="nucleotide sequence ID" value="XM_060515793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMI9"/>
    <dbReference type="GeneID" id="85399691"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF31">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR_REPRESSOR MOT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="93"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="460" mass="51819" checksum="5A86EBEBB89177C1" modified="2024-05-29" version="1">MASSLYFTAERVLLSIDFERLQAIPELLDDWARPRDSPPPDQGPLVLAQTRFILVFFASFSGEPRLIRQALVGCGHLSADFRSRMARAKPGSMNLNLSQWHSWIEHESIKRLMCCCMVLGNLLVIAYGIVTGFAALEECNIEMPAEDELWDATSASEWRSSLERRLPSSPLGLRQATAWIFGNSVEEERLDASWTWSPFAASIVMHQVAIVVWFFAHGKEACYGTTQSYRESHQSDAKRIEAALSRCRDLLTETRDGNDGTWSEADGPLLFNAFAVLRVSYGRAFINFRSLDRSLLFQESSQDMLVILQRYFDAAQERDGYMTMAVDCALEGFAIPIRAGVLLTQKTAALKWSVEHALAGWDAALLVTKWVHTVECLQSTSGKTTPEETKVLDNVRYLLGQIDVDRSPSRSLAADLARVWAGLYDDTWVWGVAPRMSWVLRELAKLYEQEASDTERQQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMS0</accession>
    <name>A0AAD8UMS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752379</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364860.1">
        <property type="nucleotide sequence ID" value="XM_060514194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMS0"/>
    <dbReference type="GeneID" id="85398092"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="78" mass="8585" checksum="8E91DF63EAB7F226" modified="2024-05-29" version="1">MTIYTCSIGMNTALGYTMIIVLPVEAPLQNRTEPDKITEVSKKHKVIMHLDGVLLGVSMSTEGCDATLEEIGRLMDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNH2</accession>
    <name>A0AAD8UNH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364369.1">
        <property type="nucleotide sequence ID" value="XM_060508373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNH2"/>
    <dbReference type="GeneID" id="85392272"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042265341" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15370" checksum="77EDC43B495A4794" modified="2024-05-29" version="1">MRAFAPVCMASTLGLGCLLPIAMPSLLVRTRKSGGAVESSIVMVLNPVSRGSDFYGAVSNTDATTPHPTIYDISNSTASKELAKHPMHAPYRVTLASSGKVWSLIVRGRFRIHFPSPCEDVRRELSSTRQRNLSFSCFVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP27</accession>
    <name>A0AAD8UP27_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein kinase ppk6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_613330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367411.1">
        <property type="nucleotide sequence ID" value="XM_060507751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP27"/>
    <dbReference type="GeneID" id="85391650"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42084:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PPK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42084">
        <property type="entry name" value="YALI0E26631P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="738" mass="79541" checksum="512F5DB80A55DE64" modified="2024-05-29" version="1">MSADLLDLDSFYQSPPSQQNQSGGQQGQVQPQRPQQVTASSTDLFDFASFTSNSNNVSSKLAAATTPAQQTVPWPSFEPQQPSGAAGGGSSSSGGWGEFGAFSSGFTSSSTSNQQPKQNLQSAEDDEGWGDFEVAEPTPTQRSFVMPPQTNKARSSPPPRNRIARASTFDLMTNNLVNVVDMPYGSGLSPIPSPGLPSPNQQAGAGSGSSWQQTNRQPSPGLSWQTASTKPAVSPGFSSQTPSAKPQPSPGFSSHIYVTQKKPSPKPAKQSDPNILFDAEEFELQGDNDDDDDDGFGDFETVQTPFPGADMSPTLDSRPPTQRQPPSQPPQQQPPSMDLLSLDDDFTPVPQPPQKRPQLSSLNLNAPTSPYPQAPKSPSFQERNPFPGLGLTTPTYGDFKKEEKKNEKPASPTPVTAWPAFGQTSPTKPPAAKKPSATTNLQKTQEEDEWPDFEDFPDDEPSAIDSSRPPESWDWDAVDGVKSSTPAPAPNSSTSSTAKKATPKSKKEASPAAPSDIPDDAPPPINIPPPSVILSIFPQLLDLANSSLFKPTSQLAAPIRKRILEDPSTVVFLRGYLLLATVAARVIAGRKLRWHRDKFLSQGMAISAAGAKGMKLAGVDKAQSAREDREAADVVGVWREHVGRLRSAVAAANSTAGAKNPRDQLRVPELNETIPVSTAKVVPTAPKPCVICGLKRDERVSKVDHEVEDSFGEWWVEHWGHRACKNFWVEHEKQLRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPH3</accession>
    <name>A0AAD8UPH3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_579355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364130.1">
        <property type="nucleotide sequence ID" value="XM_060505227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPH3"/>
    <dbReference type="GeneID" id="85389126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF26">
        <property type="entry name" value="FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041913639" evidence="3">
        <location>
            <begin position="19"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="4">
        <location>
            <begin position="29"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="474" mass="51123" checksum="541DE3374CCE6036" modified="2024-05-29" version="1">MRAGAGLVATFVAQGVAGLSCCNHTISRDVIVVGGGAAGSHAAVWLRDHGQSVIVVEKASQLGGHTAFYYDSASNKSINVGVQAWMEYKDTFDFPKRMNVSTSGSMQFTTLDYRYVDFKTGSPVTGWTAPSSDAMYPALQRYLDVLEKYEDIILPGFENFPDADAIPEDLVMPFRQFVEKYDIAAAVPQIWDSTAQGLGETMDVPTLFVMQASGVPMVRALLGTAAAAVPASGRLYELYESVAKFLGDDVLYSSTIVSTSQRSDQGISVKVAGADGTLTCIDAKRLLIAFEPTPESLAPFRPDETETEVFDKIEFTTVYAGILRHPSLQISTAYSNRSPAPGSTNYTVFPTPSQVGRIDYIGGTKDLFQFTAVGTDEDTSESMKAVIAESINNLIEAGTVPASNGTVSFVAFANHGKMHPRVTGEKLRAGFIQKQTALQGRRSTWYTGAAFSAGFSTVVWEYNNVILPKLIEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPQ7</accession>
    <name>A0AAD8UPQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetolactate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_574294</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366677.1">
        <property type="nucleotide sequence ID" value="XM_060504702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPQ7"/>
    <dbReference type="GeneID" id="85388601"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034077">
        <property type="term" value="P:butanediol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000007">
        <property type="entry name" value="Acetolactate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012782">
        <property type="entry name" value="Acetolactate_synth_catblc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02418">
        <property type="entry name" value="acolac_catab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006378">
        <property type="entry name" value="PRK08617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF129">
        <property type="entry name" value="ACETOLACTATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="195"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="392"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="60135" checksum="CA24A5A328038BC6" modified="2024-05-29" version="1">MSSETVDVVIDSLVAAGVKHIFGVPGAKIDSVFNALIDRPEIQLVVCRHEQNAAFIAGAIGRITGRPGVCIATSGPGTSNLVTGLVTANDEGAPVVAIVGDVKRVQAAKKTHQSLRGVQLLEPVTKKTTGAVHPDQISEIMLDAFRTATAYPQGATAISLPIDIMTVGTKTSIPALPQSAFTPPQYGTSPSASLSRAAAMIQNAKFPVLFLGSRAGTPDAVEAVHGFLRKHPIPVVETFQAAGSISQELAHLFYGRIGLFRNQPGDKLLSQADLVIVAGYDQSEYDADAWHKSQSLDILHLDWIPADYGAFYNPKLELVGAIAANVKALSDILANVSRPQESEVAKTIFTEFHAWEQSPQALGQTGDGPVHPLYFIKLMQGLLPPSTTLASDVGSMYIWLSRFYFAYSPKSFLVSNVQQTLGVALPWAIGASLAQEPPCSKKVVSISGDGGFLYSGQELVTAVKQGCNITHFIWNDGKYNMVEFQEVDKYGRSSGVDLGGVDFVKYAEAFGAKGLRVSRSSELEAVMKEALSYQGVCIVDVEIDYSHNHELMKNVIQDSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPT4</accession>
    <name>A0AAD8UPT4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-beta hydroxysteroid dehydrogenase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_719046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365759.1">
        <property type="nucleotide sequence ID" value="XM_060512140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPT4"/>
    <dbReference type="GeneID" id="85396038"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000252">
        <property type="term" value="F:3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF447">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE_ISOMERASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="4">
        <location>
            <begin position="76"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="494" mass="54408" checksum="E3471B39D69593C8" modified="2024-05-29" version="1">MVLEAWTTRVALGLLAALLAYLWKINRAMSTIYPEALRVSPDRWTPEKVKRTFERMEKQPIDWTPHLPPKLDRRYIIVGGSGLVGGQLAIQLIARGHPPEAIRIIDFRKPGRDDMSEGPISRVDFAQADISSESATSAAFGRSWPQAVAHLPLTVFHTAAVIRPSERSQLVYDRCSLVNTKGTAHVLAAAKTAGADVLVFTSSCSVALKPTKFFNAPWSRWPTNFFQVLDEVDFKKPIRPHEEFFANYARSKAEAERLVCSANKVPQDPTQAGGFRTGAIRPGNAIYGHKDDYLVGATVRMASFPTFTAPFMQNWVHGANVALAHLQYEAALLGPHAHKVAARPFLVTDGGPPPVFKDFYTLVQSVSVTPFHVQYPPPLILLLLAHCIEAYCLLLWSVPALQKIFSEPGLPLYMLQPASVAGAINAIINDADARRRPEEGGLGYQAKCTTMEGLCMQLGAWNRWVKSGGEKVRSEKGIVKDVLEVGVEPVARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQS4</accession>
    <name>A0AAD8UQS4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_571803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367813.1">
        <property type="nucleotide sequence ID" value="XM_060504443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQS4"/>
    <dbReference type="GeneID" id="85388342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06179">
        <property type="entry name" value="MFS_TRI12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053791">
        <property type="entry name" value="MFS_Tri12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF195">
        <property type="entry name" value="PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="60282" checksum="2DE21CF530751CBC" modified="2024-05-29" version="1">MSEAKGLAAPPSSRDEPKESIEGPDEPVPHLHAKTFLTVFAVCFIYFAQLINVVGAGAQTQNIAAVLGESDKSVWLTSTIAIMTVVLSPIVSQAADYWGRRWFLIGLTGCGVVGSIVVARASTMGMAIAGFTITGCSYGAQPLLHAVASEVLPRRYRPWAQAADNLSAAMGGLVALLAGGALTRNGNAAGVRNYWYMATAIYFVATALVLALYNPPKTTNETRFSVSEKLAKLDWVGYALLSSGLVLFCMGLSWSQNPYPWTDAHTVAPFVVGCALCIALAVYEMRFKKDGMLHHGLFRNGRNFPIALVCVFVEGLVFFAANNYFAFQVGVLYETDSLRTGLRYGVTMIVYGVSAVLAGLWCSTTRNVRWPTVVAFVSMIIFFVCMATTTPSTSDPVWGYPVFLGIGLGICLCTLVTIAQLSTPPELIAITSGLMIGVRSLGGSIGLAIYNAIITDQLSRMPTNIAAAVLPLGLPQTSLGQFIGLLVAHDNAALSQVEGVTLDVIQAGAGALLQTYSLGFRYVWIAAGSITVAAAIGAFFLVELENEFNMHIDAPAEKEDDLYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URZ7</accession>
    <name>A0AAD8URZ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_729507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366708.1">
        <property type="nucleotide sequence ID" value="XM_060512823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URZ7"/>
    <dbReference type="GeneID" id="85396721"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="405" mass="46326" checksum="510C70E4FF45039C" modified="2024-05-29" version="1">MAARLFERYKVRAEFLRVLLSFGDEPHQSEAGSANSTFVPQGDDAYTLLYKLNFVERNERSGPDAWSFRHVGVYHQHTPCFDLFILLHCQPASELAETLQDLVEEEEEVECSEELDDKSAPMVNVFRRDLCSQPAMLHHYILSCYLDNWRAYLRHLGDRFSKVLNTAMVPHAKMDHNVWVTFKSVRELRNTNDLALFASACCQSNLEVTGCILSTGKFPAAEIRSMETMLRGYIESSAVLRQRVDNTVELASYTLSLHNQQELQLLTREMKTHIKNTGDVTLKLKDLTENTVDDSAIVRIITIISAIYLPGSFVGSLFGSNYFSFNEKTRKIAIAKDFWVFVLVWLILTVFTVAAYFYTYIRKKKKKATRALKDLGDDVDEDPNNYNKPSPLSPPSARRYGVESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTB3</accession>
    <name>A0AAD8UTB3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIGR02453 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_609272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368507.1">
        <property type="nucleotide sequence ID" value="XM_060507522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTB3"/>
    <dbReference type="GeneID" id="85391421"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02453">
        <property type="entry name" value="TIGR02453 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="CHROMOSOME 12, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452:SF1">
        <property type="entry name" value="DUF2461 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="50901" checksum="A332FFF503319D0F" modified="2024-05-29" version="1">MPARKRAASPAAEDEPRRRSRRVSSTPKKSMYFEGDDDDDDFDGNAKVESDSDEVQSEGNGQEEEEEEQPKKRGRGRPKGSVAKPKAKPQPAPRRPKAVKRQKIEKVEDEYQDEQPEEDEDEEEDDEEDYESRVTIIPHEKLRGLDGQDYSDDTVHKNTLLFLKDLRAHNQRSWLKSHDGEYRRSLKDWNTFVETITPKITEVDFTIPELPAKDLVFRIHRDIRFSKDPTPYKAHFSAAWSRTGKKGPYACYYIHLQPGSCFVGGGLWCPEASHLQKLRESIDERPRRWRRVLNDERFKRTFLPKSLQKGGEEAALKGFAETNMGNALKTKPKGYLVDHRDIELLKLRNFTISKKVDDKVFTEDDAQEQICEIIAAMHPFITFLNSIVMPDFNADDDDDDDSDEDEEGENGDANDDAQENGDAEETGDEDEEEGKDWSTHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTU0</accession>
    <name>A0AAD8UTU0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_770519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367698.1">
        <property type="nucleotide sequence ID" value="XM_060515346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTU0"/>
    <dbReference type="GeneID" id="85399244"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF11">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="91"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="405" mass="46004" checksum="A88B4F13090D5C7A" modified="2024-05-29" version="1">MSCFVTKTGLTDHSIDSHLPRSAGSELNIACVLQSLAQAKSWIKDCKHEHTKCDMIETNSKWHPTRLIDIGPPENLVLTKNNAVQLFEGIPSDDLPLLYSNAVFVAHIIGIRYLWIDALCIIQEGDDFAHWRHESTLMDKIYSHVFCNISALFAEDSDGSLFSKRNPDACRPPVIWRDVEGQAIPAFLSDARFWSSEVLGQQVNTRAWVLQELLLSRRILFFGERQVLWYCRSTRKAEIWLPDAPIEDVTKLGRIEDLHLGCGKACDKPNDVRNAHLCCHDIVSTYTRCKISFPVDRLIALSAVAKEMMQVLEDEYIAGMWRHHLENELVLWSSFALQPSPSLGPQAYRAPSWSWASAEAAVVPGRPYKDCKVEDYYLEYVTGDRTGLVSGGWLRLWGTLRQMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUA9</accession>
    <name>A0AAD8UUA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_729043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367294.1">
        <property type="nucleotide sequence ID" value="XM_060512810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUA9"/>
    <dbReference type="GeneID" id="85396708"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="17128" checksum="30C468B067589A56" modified="2024-05-29" version="1">MDTISNQSVANGDLDISNTNERREEAKVLQNERIIWFLAGRDDPLFLLQQPTESVERQHVARRSAIRQVLKKLGDDKKSLDTILKGSLMIATGRPMHKASSFKTFDRDRPDESRCSYLSLTGCSSTRHPIFLSLYKERGTCGGYHRAEPTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWZ8</accession>
    <name>A0AAD8UWZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_749062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368719.1">
        <property type="nucleotide sequence ID" value="XM_060513714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWZ8"/>
    <dbReference type="GeneID" id="85397612"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="567" mass="60507" checksum="D62C1F97643A7FD3" modified="2024-05-29" version="1">MGSKHPDEKLGDTTSADPSISTEKHHVHDDPNMPETYEKQDPSHTTGDDDVVYPSGVKVVLILISLCLAVFLVALDQTIIAPALGTITAEYGSVKDIGWYGASYLLTTTALQPMYGTIYKLFSIKYAYLTAIAIFEIGSLVCALAPTSTAFIVGRAIAGIGTAGLFSGSIVILSYTMPLEKRPLAFGLIGGMWGVASVAGPLLGGVFTEKATWRWCFYINLPIGGIAMAFIFFLLTISRKNNPNGDSLMKRVLQLDLIGTAIFLPAIVCLILALQWGGAEYPWNSSKIIGLFVGFALMIIVFIGIQLWQGDKGTLPPKLFKNRNVVCAMLFACFFGAAFFPLLYYLSLYFQAIQGVSAVQAGIKILPLLLATVVASIASGALISIIGYYSAIILPSLVLFAVGSGMITTFDLDTPMREWFGYQVLAGLGIGAGFQIGVLVVQTVLPQEEVPVATACVQFFQSFGGAIMIAVAQTLFQTGLIDGVTKNAPDINPQIFINAGADQVRNILTQMGRADAIDVVLEAYMDGLRHTFYVTVACACAAFVACLGLQWKSVKKEGKGGAAAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X801</accession>
    <name>A0AAD8X801_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">R3H-associated N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_758433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000227">
        <property type="protein sequence ID" value="KAK1706419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357819.1">
        <property type="nucleotide sequence ID" value="XM_060515034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X801"/>
    <dbReference type="GeneID" id="85398932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025952">
        <property type="entry name" value="R3H-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039629">
        <property type="entry name" value="R3HDM4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32019:SF2">
        <property type="entry name" value="R3H DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13902">
        <property type="entry name" value="R3H-assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H-associated N-terminal" evidence="2">
        <location>
            <begin position="109"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="39344" checksum="F305B0E1C556BC6A" modified="2024-05-29" version="1">MAIFSAVPPPEAIDHQIPNTVSSPPPQSQTPVAAHVAAQSATAGSVDIEAWTVSALESLSVSPIARGTGTPLAINLDEQVKKASAAAVTIATEKTTTTTVQQTPIRRPLSRRDSQKKREQLLKGNEGSRARRRWENDRLIGVPNAQPPLPSDWEVHPTYPVQVVPYQVAQYWDTGLRQRIEEKTAKLQAQRKKQQRKDGSATGLSVGEVPRDLRDTAKRTPAVRGWVRVLEEPVRSFLKERSEASDAEGDSEDEEIVFVGRKGMASAGKGWKKARREVGSEKVDDGMVFDSLGDDESASFKRWLTHSISDYYGLQSHSVTTGEPARRVVYVTVREQGKRSSPKKHTVLPRPLWEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8B9</accession>
    <name>A0AAD8X8B9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_593943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000231">
        <property type="protein sequence ID" value="KAK1706109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357757.1">
        <property type="nucleotide sequence ID" value="XM_060506676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8B9"/>
    <dbReference type="GeneID" id="85390575"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="32"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="20182" checksum="A1161C903AC0D272" modified="2024-05-29" version="1" fragment="single">MRLLKILPASDTEPDNLRAEVILCLRKEAPPYKPLSYTWGQQDASCSIWLRDTEDSVWKPFSIRPNLESCLKQLREEVQEAQVLWVDATCINQLNNVEKGHQVGTIDLVYRSQRLIIWLGDSSDNSDLAIDLGPLMLSMQNGQGIVARFLENQTDETWAALIDLIKRPWFTRRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Z5</accession>
    <name>A0AAD8X8Z5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_224922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000264">
        <property type="protein sequence ID" value="KAK1704420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357432.1">
        <property type="nucleotide sequence ID" value="XM_060501765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Z5"/>
    <dbReference type="GeneID" id="85385664"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932883" evidence="1">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="105" mass="11291" checksum="C65D44C87CCC52D4" modified="2024-05-29" version="1">MQLINLLVLLPALVSAAHGDPRRMSYSGSCIIAKDGTWSPKCTTAYVEAALGSQCKELGGALSNINFQTTVTQINYRCNCVHGNTKDFTYNDGVFEAKAVIGDKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X971</accession>
    <name>A0AAD8X971_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_644011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000237">
        <property type="protein sequence ID" value="KAK1705782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357686.1">
        <property type="nucleotide sequence ID" value="XM_060509714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X971"/>
    <dbReference type="GeneID" id="85393613"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042267684" evidence="2">
        <location>
            <begin position="21"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1705782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="17622" checksum="000907437D7AB990" modified="2024-05-29" version="1">MLRPISTAAALLALLSTSEAQIPKVSGFNLVWYDDFSGKANTVPDQNNWIIDTGTSYPGGPANWGTSEIQSYTNSPNNIRVNGAGNLQITAIKNPSTGAWTSGRIETRRANFMAQPGKTMRIQASLKIPNLGANAGIGYWPAFWTLGAELLLLLLYLTPWRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9T7</accession>
    <name>A0AAD8X9T7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Hydroxyethylthiazole kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_656207</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the C-terminal section; belongs to the Thz kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">In the N-terminal section; belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359829.1">
        <property type="nucleotide sequence ID" value="XM_060510855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9T7"/>
    <dbReference type="GeneID" id="85394754"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000042">
        <property type="entry name" value="Probable thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000104">
        <property type="entry name" value="Thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="18">
        <location>
            <begin position="10"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00061283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1713776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="55782" checksum="AF9FB2ECE480ACF8" modified="2024-05-29" version="1">MPKPTVDYSLYLVTDSTPAILGDRDLSSVVAAAVRGGVTIVQYRDKTSDTGELVANARKLHAVCRAAGVPLLINDRVDVALAVGCEGVHIGQDDMELTAARKILGPDAIIGVTASTIEEALKACEDGADYLGIGTVFATSTKENTKHIIGTAGLRTILTKLAAAGHLPRVKTVCIGGLNPSNIQRVLYQSANPDASSPASLDGIALVSAIVAAPDPESASRNLLELVRTSPSYRSITSSSSGSSSGTSVDVNQLLAQIPSVITRVATTSPLSRNMTNLVVQNFAANVALAVGASPIMANYGQEAPDLARLGGSLVVNMGTVTPDGIANYLLSLAAYNAARRPVVFDPVGAGATSIRRNAVKTILAGGYLDLIKGNEGEIKTVWGEGTLEQQKGVDSSSTLAPTQKAKLVRDLARRERNVVLMTGKTDYLSDGSRTLAVDNGHELLGQITGTGCVLGTTVSAMLAAWADEDKLLAVLAGLLHFEVAAEWAAVRADVQGPGTFVPAFIDELARVRRVTVEGDLTWLQGAKVKVVNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAU1</accession>
    <name>A0AAD8XAU1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_643725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000228">
        <property type="protein sequence ID" value="KAK1706297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357803.1">
        <property type="nucleotide sequence ID" value="XM_060509689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAU1"/>
    <dbReference type="GeneID" id="85393588"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="104"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1706297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="545" mass="58466" checksum="BBE421EE880E1094" modified="2024-05-29" version="1">MLVDGCLKKRHRPHLLIWISPRSIPSTNVMASTVWYTAAAVLSFVPAFAASTSFEPARVIRSNAASQFTGCDILIHAGLSGKIFFSNDTEYAVTIQSYYSGDVRDVRPSCIFKPTTSQQVSDAIKALNSEAFGCWTVAIRSGGHSPFPSNNAANGVTIDLGGINSITYTDNPDSQGHGIAALGPGGRWGEVYSALEEQGVMTTGGREGHGGVGGFLLGGGFSWYSAKYGLSADNVLNYEVVLANGSLIEANATAHADLFKALKGGMNNLGVVTRFDLRTFPANDIYGGIVAFAFTEKEPVVQSFITMIRDNEENPAESGFVSLSWGPGRDPSVAFITANVDGVSNSSSFAGLADLGPLVDTRSAVPNSEFVKQLQGTLGLYNVWFTQSFHATMEMGRKVLEVFEAFIADLEGKLDEDATIIFVMTPLSTNFANNGPNILGLNEELTEPSVVLQVECLLPTPNDEALLTGKFEAVIDDISEYAASIGQSTKFKYINYAHQTQDPLQSYGGDNQDFLEKVAQSYDPNGFFQHRVSGGFKISKSIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCI9</accession>
    <name>A0AAD8XCI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1713002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359618.1">
        <property type="nucleotide sequence ID" value="XM_060514814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCI9"/>
    <dbReference type="GeneID" id="85398712"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221065" evidence="1">
        <location>
            <begin position="16"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="52543" checksum="696248C1312AF119" modified="2024-05-29" version="1">MRNLAFLLLASNAHAIPATLWTRTDKWEQTTCSDANITDAKVLANVRWASADTNTSWNEAVAAWQAYKPGTTSAQLKFPAFISDFYGGPEGWDCQDPVNTPCSTTVQCADTKHPAGFLLLNSFSKLHDVYQKYHEALQDAQLSISAAMGDFTSTFAPQLKADDQSTLIKTIMDVMAFGIGMASAGLWNIVIKDAAIFAGNNFGFAKDTFNSAISASFALGKDNTKSAKDSASVQNDLTSAMGALFDVWKKTQEDYLSEIFSGSNSTTIGMLESFIRDGMMNTLPVDINLSGMVNVVETIMFGQMVPIAWQVAPAAYTPFVLKTGDACSSTMPNTLNPYMTQETHDKAGVCWNGNQFYVLTVGTYRVDVQADTPGLPDSDPPFQLMAGATHDVLDGKNWGGITLEDIVISSYGGYLNNGNRNGYTVSLDDSAGGLDQLMWTGGVQTPGFFSLPVCTSLWNTLMNIAGSQVGKDNYPCGVVVEKTYPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCN5</accession>
    <name>A0AAD8XCN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Averantin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_796444</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359768.1">
        <property type="nucleotide sequence ID" value="XM_060515871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCN5"/>
    <dbReference type="GeneID" id="85399769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="57541" checksum="FCB62BE7B6CE5750" modified="2024-05-29" version="1">MTIASESVTIYDGLLLIPCAIFITIFYYTSLAIYNIYFHPLSSFPGPRLAGATPWWTALSYLGGRTPYDLLELHNKYGPVVRTSPDSLSYIKAPQWKEIYGHKAPGQLEFSKDGKYHSALKGDAVIINADREYHSYIRRLFAHGFSEKAMREQEGVLKGFVDVLFAKLGEVGEGGRPVDVVEWYNFLTFDFIGVLTFGESFDCLTTSTLHTWVQIFFALAKFMAFHQAISRLPKLLQLPATLLTMPKTLTKDVKTLNELQSEKVQHRLQTEATVPDFMEKLISAYNTGKMTYKQLEGNSQILIAAGSETTATLLAGLTYLLTQNPRVLAKLTAEVRSTFTHPDEITFTGVNSCKYLLACIEEALRVYPPSPQPHHRIVPAGGATVDGVLLPEGTSVSIPIYAASHSLLNWTLPEEFIPERWMTTKDGGNEDGVGDEDVDVRLFAGDQRDASQPFQVGPRNCIGRNLAYAEIKIIMARLVWQFDIENATEGDWIGTQKVFMVWEKAPLWVKLHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCP6</accession>
    <name>A0AAD8XCP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_721373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362467.1">
        <property type="nucleotide sequence ID" value="XM_060512379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCP6"/>
    <dbReference type="GeneID" id="85396277"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117619" evidence="8">
        <location>
            <begin position="19"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="51839" checksum="199DC0F018AF91AC" modified="2024-05-29" version="1">MRALSVFSVLIMVQPIPGIPYNKHAAKSIFGDIPDIKRESPGNLLSWIAAQSRRHISPIFQVWLGPLTKPTVVIADFQEGQNILLRRKELDRSSFMSNVLSGEAKSFHITLKTGPQWKAQRRLLQDLKTPAFLHRVAAPNIYKTALDAVLDFGFVDAAPMRALIPEVELLVSMSAANVMAEQNSQHDSDRCIQGRMDRRNLEIPILQASERSKTQFRAVDNEEKHVKSTIDLMVRRLNSVMEKEGHLLPDWIETMRAEFIADDQAVQQRLFDSIRTFHIAASSEGRLPTHSEICDANIPYLDAVIEEMPRLDHTATSQDRECKEDTVILGHVIPKGTTVIVPYKGPSYTEPGYEIEERLRSPSSRKQPPILPDRWLVRDEKGNDEYNASAGPTLPFGLRLRGCFNRKLAYLEMKLLITLLIWSFEFQKCPENLSSYGGITTLTRKPVQCYERLKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCT7</accession>
    <name>A0AAD8XCT7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_639625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000159">
        <property type="protein sequence ID" value="KAK1711557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359110.1">
        <property type="nucleotide sequence ID" value="XM_060509441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCT7"/>
    <dbReference type="GeneID" id="85393340"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="6"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1711557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="309" mass="33633" checksum="7D90CED1B1FD51A8" modified="2024-05-29" version="1">MNVATVAVAVSYGYGRHADTLSVDEKSGAMLWSIAGYPPGLLSFGIPKLAVVALLTRILNPSRWHKRFLWALSIICVVNLVGFITIIFAQCSPARSQWDSSVSGECWSKWILVSFATYSGAFCAFADVYLSVYPAVVLSKLQMNRRKKIVLSVALGFGSLSGIVVIYKCIKLPSLTSSDYTYDTVELVIWTVVEGSIIIIAACIPVLQPLGELLFGKRIFSSGNGKYLSGNSKSRLSGRLGTHKGLFRTPVKKASQEGFDADSFNSIGKTTVVGRGSQESILEQHDSDGKIVRTDAFTVTIEMSKTERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDB9</accession>
    <name>A0AAD8XDB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoprotein X</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_581760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1723012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363067.1">
        <property type="nucleotide sequence ID" value="XM_060505486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDB9"/>
    <dbReference type="GeneID" id="85389385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38122">
        <property type="entry name" value="GLYCOPROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38122:SF1">
        <property type="entry name" value="GLYCOPROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="63787" checksum="08BD6755A5B32EA2" modified="2024-05-29" version="1" fragment="single">TVTPPPATITLPGSTVVSTIAGELTTITLPETTLTLVTTQVNTVTLPPSVTTLPGSTIVTTVVETAPASTLTITRDGSTITSIAPGPTSFVVSTLTLPPVTVTLPPSTVTEITACPAPTNTPGSNSAAEYNPRSNLTWGCQPGYVCNPPKPAGCSLWADPPADDYVCAPQNCIPAPPVTLANWKENETSYYPVNDGYFNLNPNAFGLPFDIFEYEVIVSKVKGKKGHKKTTITTGNWASATELTHFPPPAQPTITPSPVPTSSAEIGKHAYKHKQEGKTYERRAFFGKRDVTIAPAICFDNCNNVYIEVQTVGKNPQICLAGSAFQMNLETCRQCVIDNADDGKETLRLYIEPQFQQWLVYCTGEAPQTSSSATILPPQSQASGTATLTTASQGAGSSDTSAVPIPGSTTTTTAEVSITITSTPTPTPSPSTSAAASSTPSTASTAESSQSPSSSGPSVSPTPSDTTSAATISPGTTAVTSSLSTVTSAAISTGSTSAGTPSSTGSVSSGSPSASSASGTSSASSSASGSSAPASASSPSTATSSSASSAPSGTATSGAGSSPSASSSSDSASAGPTTSAGSASTATGGAGGSTSETSAPSSTVSSPSTTSTGPVTAAAVKPATSTILAILAPFMILLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDJ7</accession>
    <name>A0AAD8XDJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_626919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363277.1">
        <property type="nucleotide sequence ID" value="XM_060508597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDJ7"/>
    <dbReference type="GeneID" id="85392496"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042246940" evidence="1">
        <location>
            <begin position="20"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="87" mass="9462" checksum="9E758AF22C09E26E" modified="2024-05-29" version="1">MKLSSSLLFIAQMAGTAFALSGDGAKCQLNIECLSGYCMPHTGSEEYVCWGQRRKGDWCNVNYSGIVCNSGLKCVSYQGSWFLGKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEP2</accession>
    <name>A0AAD8XEP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNARE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_578535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364537.1">
        <property type="nucleotide sequence ID" value="XM_060505137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEP2"/>
    <dbReference type="GeneID" id="85389036"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15859">
        <property type="entry name" value="SNARE_SYN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000060">
        <property type="entry name" value="SNARE complex subunit (Syn8)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="196"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="30904" checksum="63BB14D5025BABDB" modified="2024-05-29" version="1">MSTLNQLYLLADHVKLSLLERQRALSLNLDADTQDGHISRSLDQFKDGLEALDAEAKRLQGAGDESAALNITDSLPALQKQFSDLTSQFHGFSNPSTSSTTTSPNDPSLAADFDAAQSTKPLKGSLRGLPGGAAAANNSKTVRFTDSPGAAAAAEEDAAAAALFGPGRYRDDPADTAGYRDQAEGMDNQQIHAYHSQIMRDQDDHLDRLGESIGRQRELSMQIGDELDSHVAMLDEVDEVVDRHQGRLDRARRSLGKVARDAGENKQMMTIVVLIIILVLLIAILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEW6</accession>
    <name>A0AAD8XEW6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rad4 transglutaminase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_576978</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365289.1">
        <property type="nucleotide sequence ID" value="XM_060504971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEW6"/>
    <dbReference type="GeneID" id="85388870"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018327">
        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="518"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="577"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="9">
        <location>
            <begin position="647"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="767"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="812"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="874"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="822"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="896"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="929" mass="103789" checksum="EEE5195B26E77831" modified="2024-05-29" version="1">MAGRKRTRAAKSDVLDVYQEMLIEAAADAGSSAFSEPSAKRLKRPGEGKAEAVKSQATEQEGSAEDDEDADIEFEDVILPPATVQTMYRDSDDEEDDLDDDIEEEVENKEATNLDNVAYGATHHFQDSQEEPQKLTLNLSKHANATTVTSKGINKRKPVTKEEKQRRITIHQTHLLCLLLHCALRNRWCDDEQVHKTLRPLLSKKTIGYLTPSPSLPQFGQTESLKNGLEQAGAIFRSKFQITERGLRRPLWAEDPDHLKDYEPPSNMDSCLHRSDFKDAARKLSGSRDTGAQLYCALLRAVGVRARLVCSLQPLSFGSAGPSLPRPRDVKHSNKPTKEEKIRSQLLQYKSAAEEPSSSASILTSPLRRLGHPNAAAYKLPTASTSPTLRRQVEAPMKIRESSFPVYWVEVLDMGHQKWQPVDSLVTNSMWKPRQLEPPATDKENSLTYVIAFDIDGTVRDVTRRYAKAYTAKTRRLRIETVMERGEGWWRKALKPFSRRRLTDLDQIENTELNAIEAREPMPRNVADFKDHPVFALERHLRRNEVFTPDAQPAGTVAAGSRAPLEKVYRRKDVRIARSRDKWYRMGREVKPMEVPIKFLSRRSNAKPGEYADDGYGGDERNAAGTPVFTQDQTDVYRASPVVNGRVPKNKFGNIDIYVESMIPEGGVHIHDEFDTAARAAYILGVDYAPALSGFQFKGKHGTAVFNGVVVAKEYEEAVRAVMTGFEDVDAQEEQSKRSLVAVRTWRRFLVALRIFERVWAGVEPAERAEEERKLTESVRTDIDKGSDGYGTEEGGGFLIEDSVMVDDVAQTSTSAGLTSRADVRESTNGSDLERGSHSAAHNVDIGEGAAGDGVEADEGGFLVDTDEEFDNIDAVERTAGVEARPKTQRKKSLEAEEDNEVEDVLSDVTEEYDMEEDEDGGGFLLGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFI0</accession>
    <name>A0AAD8XFI0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_307315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365467.1">
        <property type="nucleotide sequence ID" value="XM_060502290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFI0"/>
    <dbReference type="GeneID" id="85386189"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="19492" checksum="CD867D225FD7F874" modified="2024-05-29" version="1">MEMWWDALADVKSQVNQSQNRRLLGAFRLSIEVPECKSSTRTTASPPKVSGQHCPRAARCLYYPRCPRRQGFCFFFMEQYGVQSTDTLVANYGYWYTTYFCGCYRLTAPKIPYAVRAKGTVASSRRPKPKIRTEGGEEEMAGEDSPSPGSRRQGQSFPGRRSLPLDAFTHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFZ2</accession>
    <name>A0AAD8XFZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase TIM barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_259702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366534.1">
        <property type="nucleotide sequence ID" value="XM_060501986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFZ2"/>
    <dbReference type="GeneID" id="85385885"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="1">
        <location>
            <begin position="29"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="29731" checksum="1095F519EF382EE9" modified="2024-05-29" version="1">MPSIARFRTLWGISPGDNFANWIALFPDLKAKGYTGVEIDYRDIPAEQLPELRRILDQFDFQLVAQIMSSWPGYVGPRPPGLTPKDHLDHYRKQLKRAQVLKPVKVNAQSGSDIWTLDQSVEFYQGTFKIDEELGFAGRVTHETHRNRSMFNPYAAKYILERVPNLRITADISHWVVVSERLLDESVEDQEILEKVIPHIYHVHARIGTTQASQCADPSDPIYRPEREFFERFWTKVIQHSATRGADYQISFTPEYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG40</accession>
    <name>A0AAD8XG40_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_719542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365021.1">
        <property type="nucleotide sequence ID" value="XM_060512188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG40"/>
    <dbReference type="GeneID" id="85396086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="18"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="42807" checksum="E2E5B13F41C282D1" modified="2024-05-29" version="1">MLGIVISFLILALLCAGMRLWTRIFIVRAVGWDDFFLVLVMISISVGSIGTCIYHLLFIQYDRFIKFMKIFYVCNGTLPISTSFIKVAILLQYLRIFERGSKSRILTIIMICLVAMWGAAFIFLAWVPCIPVAAYWDWSIPTTRRWGFGTQVAEELIRTYEAHATSNMILDFIIFAIPLPLYFNTEANKRSRKTVLGLFLLGSLVLMLSAWRLVSLVRSRAGTYPTFDPTWAAPGPMALSILEIDMAAICASLPVFWPVLQNSMGMIFVTHEVKVTTETVETTRSRDDDECLELSNGGAGNNGSFSFSQQSPVLDTEGLIEQYQQQTDIFGSYLKGKTTTDVETVPTPLRDVPPAKEPELFGSYLKGKTTTNVNADPTMKMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGT3</accession>
    <name>A0AAD8XGT3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_649543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367479.1">
        <property type="nucleotide sequence ID" value="XM_060510289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGT3"/>
    <dbReference type="GeneID" id="85394188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="8"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="167"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="27486" checksum="29964B3108485EFE" modified="2024-05-29" version="1">MASLVAAKNQLRSVMKDRLALIAHESINTQSRTVFETLKAFRPYVEAQRVSVFLSMPFGEIQTDQIVRHALSAGKHVYVPYLHKSPFPPGETPPRVMDMVRLRDIHDYESLQPDKWGIPSIDPETVHQRDRVLGVPGAESPESSFLDLMLLPGVAFDIDDNSGSLRRLGHGKGFYDLFIRRYTAKYDGEQSSPKRPVLLYGLALAEQFISRPSDGPIPVAQHDQPLHGLVLGSGEVKRPADSSYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGZ2</accession>
    <name>A0AAD8XGZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Folliculin-interacting protein N-terminus-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_581846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1723000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363055.1">
        <property type="nucleotide sequence ID" value="XM_060505498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGZ2"/>
    <dbReference type="GeneID" id="85389397"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028084">
        <property type="entry name" value="FNIP_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21634">
        <property type="entry name" value="RE13835P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21634:SF9">
        <property type="entry name" value="RE13835P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14636">
        <property type="entry name" value="FNIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Folliculin-interacting protein N-terminal" evidence="2">
        <location>
            <begin position="92"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1222" mass="134612" checksum="80292ADE688C46BD" modified="2024-05-29" version="1">MLGMLFGTSSATGASASSQSNNNYNNTTHNEAPMSLESRQEDIHTRNLLFPDTDALYQHPNENLFPLGSGLPMASLAGAFDYDGDVDLDTRHVRMLIMQDAVASFPAQLLFDSHPAPPKPPSMTTGDRPPTGMGTVQDSYRGPTSPRKSSLNQSSRPLVIQPDSPQPRQGAFDRRASMQGRTQSQAETDLQRARREYADEIHAFAGSVFGNSELMAYKGTSTKVHIVPTETRPEYGGSYLGDGRGSIGRSSMRSSRLAQSYTSDNVSPLQPQQSFTSSAPNTRSLPERRKILITRLFPVLLPSDDEAQSDTPLSRFSDHNTGFPFPQSAEDANASKKKKLQPKQKRTPMYAVVLVVQLPPSTAQMVPPSTIRSTYRGASSYTEQDSFPSSMSSARRSGWNMSGSNFPIDSMDSSCSTDVDDRMDTVTQHWDIIMRTLTHLQGVVATTLGVLLKQADISSPDPYPPSASSYASRGPSMGGRRSDEPHFVKPPKTNAKVIALQPHCLQNDNTIVQEADAARIRVVTGLSAQRVITAQGRWGIWRDEARWMARKAGEKEHGFFFFNLLTGFLATHTDWLNAMSPAWYRRKHYQQQKAKGEDDLSLPARTIIISSDKMMARRLIFLLSAFLPSHQHLSSTRAHRPSTSTSFGAFSQSPPSLIIPILREESLRRKINRRTGPRRVSHSRTVSQSTRASGVPPQLAHLSMESNHERRVSDAASIRSNLPIPGNDQVSRKSSAATTTTITPETTIPHFATAQRFETRRSLRPGSSGSVAADDLKRTLKRGESSGHVSSASTDSRMSGSRWGSVISTLWNGKRRDSTGLTTPSQPYSSNPTSPTKSGPGGRRDRLAEMVREVGPEGYRRTDDRIHKTESNGNGPTTPRGFDDQAVEDAPERVSFPERVPDPSGDFRSPVKTSINAEDGVIDVDIPFPDYITSFETAVSSPSSSGYLSTPGIGNGLEGFEQFSRITIDGDSPMNVAGFLQRYHQDFILQAVPPQDTLMEDIKRSMRAEPTPFITQPFYSAEQPADRWVDVSSALIADTTTHTIKRIRYRRLIRPKPFTDRSAPLGSAGSSAYGNAPMTPSILPYEMQLDDEFIEEPIASLDEVLIDAVERVIAQSNEVSKQSSSNSSRSTSKRRDRSNSEASVSVDSRHTTRMPVPSQEVPRDQCKTVVLSALDEIIRDVIGERDHDTPDATVHAVDRDRESTLKEAVRVWLEAVDPSEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHB1</accession>
    <name>A0AAD8XHB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_616175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366341.1">
        <property type="nucleotide sequence ID" value="XM_060507955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHB1"/>
    <dbReference type="GeneID" id="85391854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3620.10">
        <property type="entry name" value="YdcF like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051599">
        <property type="entry name" value="Cell_Envelope_Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336:SF20">
        <property type="entry name" value="DUF218 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336">
        <property type="entry name" value="INNER MEMBRANE PROTEIN, PROBABLE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36245" checksum="54DB3907DC24A192" modified="2024-05-29" version="1">MPNACQLVSMANAACAINTLSSFLSHEEIEDVDGLNQFFRSLTDPAAPSSLEQHQATDAIVFCASSVLSLADVVFSAVNTNGLESKEQISKEGRNTVLVLCGGIGHSTPFLYEAIKRHPVYNVLADEVQGKAESRVLQLIAERWYGIQIHDVGTVEATIQPDDTNKLLVVVEDRSTNCGGNAAESKRVLEACGVCSPRSIVIVQDPTMSRRTVATFQRAYEEQCTALPQIKSWPTFTPQVKFIDTSQGNVDEDVMAQLVFDNKECAQKTIGGMWSIGRFVDLLMGEIPRLRDDEEGYGPRGNDFIIHVAIPESVDVAWAMLYSLVGKQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHF6</accession>
    <name>A0AAD8XHF6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_651715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364988.1">
        <property type="nucleotide sequence ID" value="XM_060510474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHF6"/>
    <dbReference type="GeneID" id="85394373"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="24513" checksum="ECCFA85D5CA89CF9" modified="2024-05-29" version="1">MSFSFRHYLAAGIRGMRVATGTSYEDIFDQLFQALNVLRREAAQSGDIRLYSEEYFPDDIYDPPSPEYINLTGVPRHVSSTPSPAQPGHQVNIPIRLSETPQPTAFVQPIIYPTDPNAPIPAVHNPPPEPVYNPHTEMPRRKGDEGDKLWPCEYDGCDASYTRRKTFLDHMVAKHGYPAPPKRPSRPRNPANATASSSTQAQAGPSGSAPRNEGEDVNMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI87</accession>
    <name>A0AAD8XI87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-galactopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364405.1">
        <property type="nucleotide sequence ID" value="XM_060514242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI87"/>
    <dbReference type="GeneID" id="85398140"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000220">
        <property type="entry name" value="UDP-galactopyranose mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734:SF4">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43734">
        <property type="entry name" value="PHYTOENE DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="513" mass="57399" checksum="9FD1F36CAD33B63D" modified="2024-05-29" version="1">MADINVDVLVIGAGPTGLGAAKRLNQINGPSWLLVDSAEKAGGLAGTDTTPEGFLYDVGGHVIFSHYKYFDDCIEEALPKEDDWFTHERVSYVRYKGIWVPYPFQNNISILPKEDQVKCMNGLIDAALECRVADKKPKDFDEWILRNCGEGVANIFMRPYNYKVWAVPTTKMQCAWLGERVAAPNLKLVTENVVMNKVAGNWGPNATFKFPARDGTGGIWIAVANTLPKEKTRYGEKGTVEKVDAEKKIVTLKDGTKVQYGKLISTMNVDQLVERMGNQELVSLSKGLFYSSTHVIGVGIRGARPDRIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEADVKLPTLYLANGEKASSTEAKEGPYWSIMLEVSESSMKPVEQEKLLQQCIQGLINTEMIKPEDEIVSTYHRRFNHGYPTPSLEREGVLKDLLPKLLDQGIYSRGRFGSWRYEVGNQDHSFMLGVEAADNIVNGAVELTLNYPDFVNSRKNEERRLAASFAFGSQANGIPSHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIL3</accession>
    <name>A0AAD8XIL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AFG1-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_101632</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368827.1">
        <property type="nucleotide sequence ID" value="XM_060501027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIL3"/>
    <dbReference type="GeneID" id="85384927"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF2">
        <property type="entry name" value="AFG1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="536"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="619"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="685" mass="76743" checksum="9E067F1C7C707741" modified="2024-05-29" version="1">MISHTLRMPKARKMAFTIRRYSTAMAITDPLVKYRTLVSTKVLSPDQDQHRLAIHLQKLYGRLKDYAPEVDYRERLKQVADIPEARDPEEAAATLAMPSHPIWDNPLFKHLARKAMLDTKETDPMALVHVMTSLEGAITINSPRGLFLSGEVGVGKSMLIDLLAQGLPTERKRRWHFNTFMLYTFSQLEKFRQSHTELDGNEKEYAMLWLAKKLVEESPILFLDEFQLPDRAASKILSHLFIAFFHLGGVLIASSNRVPEELQKAIGIEYTVPPSDGFLKSLFLGGARSRGTRHSQNDFAAFLEVLKARCDFWHMDGATDWRRRETEVKVAVDAISIEGTGLAAEPADAQEETPKEATKPAKYFLTPETSEWSSELSDHLSQPWSPATLTVYGRTIPVPRQRDGVAYWDFDALVATFGPADYVTMASTYHTFIIDNVPTMTTLHKNEARRFITLLDALYEARCKLFVRAQTGPDDLFFPDIRAAQAEMAAAAEAAAAAAASGEEVVSSDAIYSETIAEVYQDSAAPFRPNISYYDTDAPTSKYDPDQDSDFGRAGNVSSSNTTSPNFSNTAGFIGEDERFAYRRAASRLWELCSAAWHARGSSSGDPSEWWTPVPRTARHWEDSAPSKPKRDEPLLPRRQSDAVMGPSRPVDEPFGTDKLVIERWTALEEAERRREKSASSSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIW4</accession>
    <name>A0AAD8XIW4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_609173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368486.1">
        <property type="nucleotide sequence ID" value="XM_060507519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIW4"/>
    <dbReference type="GeneID" id="85391418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121525" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8408" checksum="3D831351E9826D5B" modified="2024-05-29" version="1">MWLKLSSYWFALEIFGLTRGASSHGKKKKKKKGCYRSQAKPARVPPRRTKHKRMAIKLISLTARYHKQPEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJB6</accession>
    <name>A0AAD8XJB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_571947</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367718.1">
        <property type="nucleotide sequence ID" value="XM_060504452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJB6"/>
    <dbReference type="GeneID" id="85388351"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="548" mass="62016" checksum="2205AAC6773B88E3" modified="2024-05-29" version="1">MKPPKACRQCRESKRKCLRRSLAVGEPCDTCRVRSLPCASSLSRVPPSPLPLLPRPEPTPSLSNTSTPTSSKTEGTDLPLHTAVLLVDYYLDKLHNRPHSLFHPAKLRQEVQDGSISRILLLAICSMGSRFALDEETRALEAGLMEESKRTLLANLENVCVENIQACILIANLCAAHLNPSSEALFFRTGISLSHIMQLGTSTVGSRLVDLEIHRRIWWSLFMADRWSSSSLRLLPQIRDTELAVDLPMDEAIFESLDPTATQLEKPWQPGIWAFKISLVQLFGPIQQLNRHSVNRSMTAEDIESSILSLSQQLETWEESLPDNIKWKEEMLDWHINRGTGGPYVALHLGYHHYSVLLYFRFLSSQEPRSPASSMYHSRCKAHASAYSNLVKLARGRQGCEVVYPTVGHMAVVSSSVLLHTLLFGEEADLKSARDALNANFAAIVELRQYWPNTAPMIERLATFQNFCLLSCDSRTHDFDDWMVRFLTEYSLPLEEKDIQHVRSGMDYDIDSFSARTQALTQQGRYTSFQTDTSDAYSLQLHEFDYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJE1</accession>
    <name>A0AAD8XJE1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_718539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366385.1">
        <property type="nucleotide sequence ID" value="XM_060512087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJE1"/>
    <dbReference type="GeneID" id="85395985"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43491:SF2">
        <property type="entry name" value="UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="4">
        <location>
            <begin position="71"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase dimerisation" evidence="3">
        <location>
            <begin position="249"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="49655" checksum="A1E9DF344729C4D9" modified="2024-05-29" version="1">MDAQMLTPDTPERFPTCHNGYPFDSPETKPQAWDFPHDGYYPITPPTEECESDEELATVASSIDLEAEPLVAVIGVGYVGEHLVGNFARKFNVLGFDVSEARVQGLGEEFGPDSKAKFTCKPSDMAAATHFLISVPTLLRPDQTIDASFLKSALKNVATYARPGSVVVVESSVAVGMTRELLGPLAKERHLFAGMSPERVDPGRVEPPAFAIPKIVSGLDDMVPGSLNAIVRLYSQVFDNVVPVSRPEVAEMTKLYENCQRMMCIAFANEMADACLGHGVDPYEVSGAAATKPFGYMPFMPSLGVGGHCIPVNPYYLLSNSQFPLLQHATEKMRARPMTIAQRAVDTLCAEKLRPSVLVVGMGFKKGQSHLANSPGLELAKSLVLTDKVDVCWADPLVKQEAVPQIARLDVEDWNARSLEQRFDMIIVAFRQTGLDFDVLNQLDKTRVEMWCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJP1</accession>
    <name>A0AAD8XJP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_227130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367120.1">
        <property type="nucleotide sequence ID" value="XM_060501778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJP1"/>
    <dbReference type="GeneID" id="85385677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="38354" checksum="3AD6A9EB8BB6D073" modified="2024-05-29" version="1">MVSVKISLQLLVSATQLEVLDMECSGSLLDSEKLNSNEKQIKRLKKVIRGNLRTLKTLEAQSRRAGQSTVPFAYRTQPTSSLYELLVPLGRSMAETGCVPKPKSVSATSSESSTRTKEPYKSSLAGISVPSDSSAPSRGAEFQKDASSYDHEALYKEERRSQYERLSRNRSSSAKTTPPSPPGPPATVRSVNHGSGASSNMREARSVLALQLQRQQSETLPKRVFEVNTANFDKLLARSQVLENGQLSGKTVTGRVNTTLEVSIISITEAGRLDLNVISCEQDKETEFKFDQGKNQPCIGMVTFTIYHSRIASSQSPTTSHKVYVVEHCRPELIFGKNFFDRDGNSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJQ6</accession>
    <name>A0AAD8XJQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367240.1">
        <property type="nucleotide sequence ID" value="XM_060510310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJQ6"/>
    <dbReference type="GeneID" id="85394209"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="214" mass="22377" checksum="CE58D567685F71BF" modified="2024-05-29" version="1">MDIENILPYLSTLPLFTLRGYPAYGTKYSRKAGGWDVGYPIYTACHRPSTISYGKASIRYLSLYPLTLGTGNDSQGPGLLSPGSLIPSRPSACRSTVLTSHHGAALSVSVRTLRTGAALQAPQLAPPPPASTPSSSLLGDLLFSSSAITEYSKIFLSSASSAGPQLYLTCPLTIPPTTVLSSLSPGTSGRMEDGGPVQCTKHQAPAKQPRGLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK78</accession>
    <name>A0AAD8XK78_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_748703</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368952.1">
        <property type="nucleotide sequence ID" value="XM_060513657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK78"/>
    <dbReference type="GeneID" id="85397555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="8">
        <location>
            <begin position="59"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="9">
        <location>
            <begin position="209"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="252" mass="28606" checksum="5546B71D8E8C932B" modified="2024-05-29" version="1">MALHPPPESEKLIFAPAGSSQNTRADQFTLGRLSLPSLHPTSPTHQFNTWFTAAQQTHAVSHPETCTLSTASLPSGRVSARMVYLKELDAKGGFVIYTNLGTSRKAADLASNPHASLTFWWEALQRQVRVEGRAERLSREESQVYYDTRVRGSRIGAWASRQSQVLEPQEGVKGEEGEKDDGRAQLEGWVKEVEERFEDQETIPVPEFWGGLRVVPERVEFWQGRDSRLHDRFVYDKVEGEEEKWTINRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKC8</accession>
    <name>A0AAD8XKC8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Folic acid synthesis protein FOL1</fullName>
            <ecNumber evidence="10">2.5.1.15</ecNumber>
            <ecNumber evidence="12">2.7.6.3</ecNumber>
            <ecNumber evidence="11">4.1.2.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24">Folic acid synthesis protein fol1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">BDZ83DRAFT_569351</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Catalyzes three sequential steps of tetrahydrofolate biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the DHNA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="22">In the central section; belongs to the HPPK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="10"/>
    <dbReference type="EC" id="2.7.6.3" evidence="12"/>
    <dbReference type="EC" id="4.1.2.25" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369009.1">
        <property type="nucleotide sequence ID" value="XM_060504182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKC8"/>
    <dbReference type="GeneID" id="85388081"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000006">
        <property type="entry name" value="Dihydropteroate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="25">
        <location>
            <begin position="212"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00012458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00013043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00058009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00061548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00067568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00068111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAK1728954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="481" mass="51739" checksum="DC39DF425606E76C" modified="2024-05-29" version="1">MSTGAAQTRSACGCACSGGGGCGSGAAKPKGPSTAYIALGSNLGDRVAWIEQACAEMDRRGIKVKRTSSLWETEPMYVLDQDRFVNGVCEVETELEPLALLDELQDIERTLGRKKLIDKGPRNIDLDILMYGDEKIEHPRLNVPHISIPEREFVLRPLAELIPEKPLYASNPWKLTLDYLNELPPSAAPLSPLTPISVSHPPLAALTSSRQTHVMAIINATPDSFSDGGVHNAQNLVATLKSFAAAGVTIVDVGGCSTAPGRPEVPADEELARVLPVIKLVRALPELAHLAVSIDTYRASVAEAAVAAGADIINDVSAGQLDPAMIPYMARSNRTVCLMHMRGTPATMNSLTDYPDGLIPTIARELLERVAEAEAAGVRRWRIVLDPGLGFAKTGPQNLEILRHMDELRSWPGLEGFPWLVGSSRKSFVGKFTGVSKPQERIWGTAATVVSAVQGGADIVRVHDAVEMCQIVKMADAIYRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL36</accession>
    <name>A0AAD8XL36_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_716498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase-activating protein for the ADP ribosylation factor family.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369443.1">
        <property type="nucleotide sequence ID" value="XM_060511853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL36"/>
    <dbReference type="GeneID" id="85395751"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07608">
        <property type="entry name" value="BAR_ArfGAP_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000051">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000017">
        <property type="entry name" value="ARF GTPase activator (Csx2), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="643"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="825"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="519"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="781"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1058"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1078"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1105" mass="122413" checksum="C7848639A1F0D96D" modified="2024-05-29" version="1">MGIVSSKPDDGATLYLRDQNRLSISSLVISNPRKRSSVNIVPNAFPATRVSASRPLGDGSPIEFVQDTEVVTSPGGVPNFILKLNQDDELVFTFTFVIRQGQQFVTNSGADAVATTDTQISGLTYVYASTPREVENLVTREFHADPNLHKNSNVELVGDFATGGTPSVSFEWTWKWKPPKSIEDRGGGWRNSCSFVEYDPRAHCLHTLASFSYWVSNPVLPLSHPNSPSPPFLLTAPPKIRVASSQSVDSRISHAELDEPLSPLPGNTSSTTILPVPQSASEPIKVDVACPKPTDDVLVPDDGPVFRATIKSLEQKTGNMRTQMKRVLKMAKQAHEAQQEANKNFSEFIDTLREASSTNANAVQPAIEHYFDKIAREILAYERTNTVNLKRIVIDPLDKFYTVDIKQAESKKRDFEEESKDYYAYVSRYLGQRHDSVKAKKLAESDSKYQTKRRNFELKRFDYSSFMQDLHGGRKEQEVLSHLTRYADAQTKSFLEAAKKIDTLLPQLEALSSEVQEADKEYQYQRREREEKRRLLEKSNQPYNEPDPIPVPGTSSGPVASSNGNAYVSDSDLGRADSTGSQLKVAMSSGSNPSLSMASPELSRSPGSLGNSSVGSPAQASKFKGIRDLEEKDYGQSSGASSTQRKEGLLWSLSKGGSNHVDPRNLNKQGWHKFWIVLDQGKLSEYSNWKQRLDLHNDPIDLRMASVREARNAERRFCFEVITPQFKRVYQATSEEDMNSWITSINNALQSAVEGRIMRDKSAPSDSGYIKRDIGSILTGKSPSVGHNSHHSHANSNSAPVRRITVGARPSTHRSTSSSFDENPDKLLQLLRDNDQGNCWCADCGSGTKVEWVSINLAIILCIECSGIHRSLGTHISKVRSLTLDINSFTSDIVELLLLVGNRVSNMIWEAKLEPGYKPTSQATREMRLRFITAKYVDRAYVEPISATLSRYPNPDDTLLAAIKKNEIQQVIYALALRASPNVTDRSRGTHAVFLALAAADPASPSPTPGQPPETDRTVPFPVAEMLLQNGAEVPLTMPAFPLSRSAQLYIEEKRGRSTGFSNDSVGSLPGNLSPNEKLQRERDARLQKRVSAGGRLAKSPIPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL94</accession>
    <name>A0AAD8XL94_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_762181</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369449.1">
        <property type="nucleotide sequence ID" value="XM_060515201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL94"/>
    <dbReference type="GeneID" id="85399099"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="172"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="273"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="827" mass="91157" checksum="7F0111DA077F425C" modified="2024-05-29" version="1">MRRIPLNDDAEEKARRAHSRHAFHERQRNELKAAAATPLRRNNNSLEDIENDTPGSNPKTPHARGSRGSRQVVDDDDDEGFVVSGSAVTPMKRVPILANFEEWMKMATDNKINANNSWNFALIDYFHDMSLLKEGDGVNFQKASCTLDGCVKIYTSRVDSVATETGKLLSGLADSNNKKKGKEGDEVEDEESEEEVDEDGNVRKKPKRKTQRSSEATLAPNFSSLQLKKFELEFAVDPLFKKTSADFDEGGAKGLLLNHLMIDAQGRIVFDSSDEVGDAHTSKTRKKNEDADDEDDENTEMQDASVVQEEPEQEENTEDVEIDLGALGAKFFSDLARLDELDVCPSLKNFDLGDPSGSMDIPFLRAPEDWRGDQDKDKNLGDNSGMFIDGDNAAGFDDDDLGLGGFELGADVAFGEGGEAWAREAALEPQMRVYDAGLGEEAGDGDGVEMMDPDNGDFVVSMSHAKSADKMHEDILGYFDQALQKNWSSAEHWRIRKIKDVNKPVGPARVRKEKEPFEIDFSAPLDQALADVLYTQASSNSAISMPKKDWKSKSRNLLPDDKHFNSKSLLNLFLKPKARLGRRRVLGNRGGMFGNAGQDRDVPEGEMDEAFWANQKAPVKSEDEPLPEGDYDANFFQDDALPFAGGLDDDDDEFADAREHLSPGAEGDVGATEALGMTALLGGDATTNVLTGAFGTTLVTQTRRMRPDYVQFARVAKKVDVRRLKEEIWKGMGLEGLDGDSTRLSSPDAPAPPVEPPAKDTELKFTEVMNGLGSVYPKAMMEDISTSFCFISLLHLANEKGLVIEKTPELTELNIRKDWTAEIVGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLC2</accession>
    <name>A0AAD8XLC2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_716275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369494.1">
        <property type="nucleotide sequence ID" value="XM_060511836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLC2"/>
    <dbReference type="GeneID" id="85395734"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="498" mass="54663" checksum="31C521E36568DD32" modified="2024-05-29" version="1">MDSSEFRTAAAEAIEDITKYYDTITSQPKVLPSVTPGYLRPLLPQSAPEDPESWQTIHADLQSHIVPGITHWQSPSFHAFFPCSSSYPAMLAELYSNAFNGAHFNWICSPAVTELETIVLDWLAQLLNLPPAYLSTAPTRGGGVLHGTASEAILTVMVAARDKFLRARTAHLPADSEEKEEETWRLRSKLVALGSEMAHSSTKKAAQVLGVRFATVPAPAETGYAMSGAALTSTVAALRAKGLEPFYLTATLGTTDTCAVDDFPGIKDALASDEQDSIWVHVDAAYAGSALILPQNAHLTAPFAAFHSFNVNPHKWMLTNFDCSALWVRDRAWLVESLSIKPAYLRNQFSEAGLVTDYRDWQIPLGRRFRSLKLWFVLRAYGASGIRKHLERGIRLGERFAEMVKSRGDLFEIVTGPRYALVVFTCKAGDREKSNKVTETVLEDVNGEGVIYLTPTTLHGLYGIRMCTGSSQVIEEEHVQKAFDIIVAATEKALAGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLF2</accession>
    <name>A0AAD8XLF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_716334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369595.1">
        <property type="nucleotide sequence ID" value="XM_060511845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLF2"/>
    <dbReference type="GeneID" id="85395743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF5">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="520" mass="58206" checksum="0DFDE190DFAE2BEA" modified="2024-05-29" version="1">MDSNQSTSAWTTTAACVAIVVLLILIRPRSSWGHPPLPPGPPGEFLLGHLRVIPKENTAQTYAEWARKYDSDVIHVKSLGQSIVVLNSVEAAKNLLDRRGANYCDRPRFTLFEVMGWGKTLTFLPFGPRWQMHRKLLQTTFSNTNVRQWYPLQVAEARKSVHDIVSNPDSWQMSMKRFAVAIVLKVSYGVDVHEDNDPYVKIAQDAMYATGNGGAPANSIVDIFPPARHLPVWLVRDWSLKFAREWGWAIRKLHDVPFAVAQEELARGKDSPSFAHRLLETYTSNAKRGLDNEWSLDDIKGAAGAIFIAGADTTWATMVVFVLNMVLHPEIQEKAQACIERVVGLDRLPDLSDRPSLQYIDHIVQEIYRWSPLAPLGIPHKSLENDVYNGMFIPKGSIVFFNSSAMTQDERVYKDPKSFNPDRYQPESSGGRGEPLPLGQFGFGRRVCVGRFLADNSVWIAVATMLATLKIGKKVGPDGQVMEPKIAFTNGGTCHPEHFECSITPRSQRAQELLRQSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH8</accession>
    <name>A0AAD8XLH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369568.1">
        <property type="nucleotide sequence ID" value="XM_060507334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH8"/>
    <dbReference type="GeneID" id="85391233"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="82" mass="9521" checksum="43EF9AC3072082B4" modified="2024-05-29" version="1">MSRLQPNILRIYLSMPVAAAVSFVQSEKEKRHVHKSRENIQWRQNNDKKKIQTSRGTMLQRTFDRSGPLETIGSGHCRLNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLP3</accession>
    <name>A0AAD8XLP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_568135</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369731.1">
        <property type="nucleotide sequence ID" value="XM_060504032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLP3"/>
    <dbReference type="GeneID" id="85387931"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="145"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="357"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1729676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="59650" checksum="D7D6B5AB7706717E" modified="2024-05-29" version="1">MPPSAAPRRPGRAANDEVPASSPANSSGSESESDYLDSPASRKRRRTDPTAEPDLEDIENDDEDEEEELKAVVSTIQAPSRFKRAAAAVDQAPQTSRPAAPSQNAITAPTDPNTTFSAINVRPWLVQSLANMAIKRPTGIQKGCIPEILKGRDCIGGSRTGSGKTVAFAVPILQKWAEDPTAIFGVVLTPTRELALQIFEQFKAISSPQSLKIILVTGGSDMRSQAIALAQRPHVVIATPGRLADHIRTSGEDTICGLRRVKYVVLDEADRLLDGTGPGSMIPDVEECLSVLPPSSKRQTLLFTATITPEVRALKDMPLKPGKQPVFVCEVDTQALAIPATLSQMHLQVPVTHREHYLHTFLLTDGNEEKSVIIFCNRTKTADYLHHLLRMLDHRVTSLHSALPQRQRVDNLGRFRAAAARILVATDVASRGLDIPEVGLVVNYDIPRNPDDYIHRVGRTARAGRKGEAVTFVGQRDVELVLAIEARVGREMEAWKEEGVNLETRVLRDALKIVSEKKREALLELEEGREVGGKRKRTKQKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM87</accession>
    <name>A0AAD8XM87_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dolichyldiphosphatase</fullName>
            <ecNumber evidence="11">3.6.1.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_662169</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a di-trans,poly-cis-dolichyl diphosphate + H2O = a di-trans,poly-cis-dolichyl phosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14385"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="EC" id="3.6.1.43"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dolichyldiphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.43" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370016.1">
        <property type="nucleotide sequence ID" value="XM_060511068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM87"/>
    <dbReference type="GeneID" id="85394967"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047874">
        <property type="term" value="F:dolichyldiphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03382">
        <property type="entry name" value="PAP2_dolichyldiphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000003">
        <property type="entry name" value="Dolichyldiphosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039667">
        <property type="entry name" value="Dolichyldiphosphatase_PAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF1">
        <property type="entry name" value="DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="12">
        <location>
            <begin position="54"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="26165" checksum="EC9F69BFF7A2D697" modified="2024-05-29" version="1">MDQDTRPLASLSLTHVYYDPDDSLSFLCAWLALLPQALCIVYATLIWSTREVEIALMFAGQLGCEAINFALKRLIKEERPRRIHGKGYGMPSSHAQFVAYWSVFLVLFLLVRHRPSSARRHHRPYSLVERVVVSVAALGIAAAVAWSRIYLNYHTEKQVMVGCLAGTVCAIGWFLVTAIARDFGLLAWGLQTPVARLFRFRDLVVEEDPCQAGWDKWEERRVEADQQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMA6</accession>
    <name>A0AAD8XMA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370021.1">
        <property type="nucleotide sequence ID" value="XM_060510090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMA6"/>
    <dbReference type="GeneID" id="85393989"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018555">
        <property type="entry name" value="C630.06c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09428">
        <property type="entry name" value="DUF2011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="28418" checksum="7EF64EF2C97A832F" modified="2024-05-29" version="1">MFELPDAKRVRRQDLGESSGDEGADHDEQQNADLLAKLHARMAGMLDLGDADADQAPTEMTEQPATATDGETGGNGGGEDEPEEFEFRLFTTSNPATKIALVDEDERAMAGDGAMIRKRPLSYYIAGEPTPEVKAELAFAAVSGEEVLERAQRRWWGMEQPWRVTTIPGITVSSKGTAGTAAGDVGETKEEADAAAARRRRPGKKKRLAIRVKQRERVKKAEELEKFKAGSQIDMSVLFQTFSAAEEKSAEPIRKSMMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNS0</accession>
    <name>A0AAD8XNS0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_600470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370799.1">
        <property type="nucleotide sequence ID" value="XM_060507036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNS0"/>
    <dbReference type="GeneID" id="85390935"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000008">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.70.10.10:FF:000001">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="10">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="29481" checksum="56EB35D057635601" modified="2024-05-29" version="1">MLEARLDQADILKKVVDAIKDLVQDCNFDCNDSGIMLQAMDNSHVALVSMALKAEAFSPFRCDRNIALGVNLGSLTKVLRAAQGDDILTLKAEDAPDSLNILFESSANDRISEYDLKLMDIDQEHLGIPETDYASTITMPSSEFRRICADLIAMSESVTIDASKDGVKFAASGDIGNGSVTLRSHTNVDKPENNVDIELSEPVSLTFSLKYLVNFCKAAAISKQVKICLSNEVPLLVEYALAGSSYLRFYLAPKVSLVSFLTLNTIKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP86</accession>
    <name>A0AAD8XP86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_298607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371190.1">
        <property type="nucleotide sequence ID" value="XM_060502232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP86"/>
    <dbReference type="GeneID" id="85386131"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="192" mass="20820" checksum="BFF6AA1A86E9361F" modified="2024-05-29" version="1">MQTACSARYLIEPCLLPLDCLKGQGIGGRRTEAAGMSNPRSGIADRCPQGSNILPPLCLASLASRRHPCSVDCYSGTTTAHMSLQADTPRPGKPVTQPSQAAYDTSACLSGFTFVYIVHHHSGPQAAKKRNHDHGRSSKEAVNSHHHEIATRQLTMPSMEAAPTFFAPIQFIVHNHGHGHVHLSLPRLHLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPL6</accession>
    <name>A0AAD8XPL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dephospho-CoA kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371275.1">
        <property type="nucleotide sequence ID" value="XM_060503710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPL6"/>
    <dbReference type="GeneID" id="85387609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001227">
        <property type="entry name" value="Dephospho-CoA kinase CAB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="274" mass="30184" checksum="0B3C75657E017F0C" modified="2024-05-29" version="1">MLFIGLTGSIATGKSTVSSILSNPPYSIPLIDADVLARKVVEPGSKGYAAIVKHFLPTTPDLLVPVSEAMPEAGPDGKGRPLNRPALGKRVFGDTEELKKDRAVLNGIVHPAVRSEMYKAILRAYVTGHWAVLLDVPLLFESSLDRLCGTVFVVAVKDPEVQMQRLMARDPHLSREDAENRVLSQTDVRLKARRCEARGGGKGVVLWNDGSKEDLKRDIGEAIRHVQASSPVWWSWLLLACPPAAAALGAWRFWQNVRINKAWAEQERIEKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPR7</accession>
    <name>A0AAD8XPR7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Actin cytoskeleton-regulatory complex protein PAN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_725850</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the PAN1 actin cytoskeleton-regulatory complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Actin patch</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371393.1">
        <property type="nucleotide sequence ID" value="XM_060512745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85396643"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000349">
        <property type="entry name" value="Actin cytoskeleton-regulatory complex protein PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013182">
        <property type="entry name" value="DUF1720"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF173">
        <property type="entry name" value="ACTIN CYTOSKELETON-REGULATORY COMPLEX PROTEIN PAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08226">
        <property type="entry name" value="DUF1720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EH" evidence="18">
        <location>
            <begin position="237"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="18">
        <location>
            <begin position="506"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="539"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="655"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="845"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="931"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="753"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="106"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="671"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="944"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="977"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1027"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1080"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1144"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1170"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1202"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1217"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1269"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1331"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="1396"/>
            <end position="1467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1731338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1505" mass="162281" checksum="2918D940541E5C6F" modified="2024-05-29" version="1">MYSNSNAFLGGNSQRPGAQQYGGSSFGQQPGQQQQQPSPFAPQPTGFGQAPLQQQFTGYPGMQQQPQQQAPQQLQPQFTGFPGQAQPQQSFQTGAPPMPSIPSQYQSQFQQQQQQQQQPQQTGFPGQQQQSQPTGFAQQQQPQQTGFPGQQQPQQTGFAQQQQPQQTGFPQAQQSQPTGFQSQQQTAAPAPIKPQATGFSQMAASFRTGGTPKPAGRRPKSANKIPNIRLSFITAPDQSKFETLFKSAVGEGQATTMSGDKARDLLMRSRLDGDSLSHIWTLADTTRSGELHFPEFALAMYLCNLKLTGKSIPSTLPENIKNEVSSVVDIINFSIAEDAGRDTPGSTATGRSSTEPTIHQPQPQTSNSQLLQAQMTGFPGQPAQGFGQTQGLQPQQTGFPNLNAQPTGMNPQPTGYNGPRPPMPPMPTGYGNSLTPGGGPMAAPLNAQPTGRPGQWGLVNAPSTGLPNIDALQARMMPQQGREQGSFTTQGLQGNAVIPWAITKEEKQRYDALFKAWDGLHKGFIGGDVAIEIFGQSGLEKPDLERVWTLADNGNKGRLNLDEFAVAMHLIYRKLNGYPLPNQLPPELVPPSTRNFNESIGTIRSMLSQESEFRSKSGAALLPQKTGVSYMKTHSLRGTPGGQSTGRKDATVFKNNDEQVGYRSSARRRVGNNSPRPESPSSTAYDDLGLDQLRKKIREKEVLLDAMDFADEKNLEEDDLLDRRDRREAEELYRRIRRIQDDIDANPDAALSSGDSEAERRSLKRQLQTLTDKVPELASAVRKTEKAIAEARLELFRLRDAKAHPNSAAAIVGTGPGGAVTESDRLKARAKAMMQQRTAALTGKKVESSFDDEGPKRLEEENHKIKTEKENNESMVRDVEDSVRDFARGIEDNLKEGTTTASNEHEKRRWEDALGVEDEVRDFIFDLQRSSRAARVRAQDRRPTSSSSPSAARASSREPAAASPAARLESPAPPSRTTTPGGSYSSYKTPEERAAFIKQQAEQRMAERLAALGIKAPTKPGETAAQRMERERAERAAKLRQAEEEDERRETERQARLAEETGAPAPAAKKPPPPPSRKAAKSDAAEREASRKAEEEQAAKQAEEERLAREHEEQQRATKELEASAREQQDDLETERQSAAARLKALEEQVKQGKLKKEEEKRKKKAALAEQKEKEAKLAAQRAEIEAARQRELELQRQLEAMNDDDDSSSDDEDGPSQITPQASTPTQGGSQISSQELEKQPSPPPVPTVVTSPPTENESRNPYHRMLSHSSESTSAPSEPSAPAAAPPPPPAAAQSTNPFHRMAQESKAAPAAASPPPPSGPFSRKRPDEDDDWGTDKEDDEDSDDDDRPGGSSAAALASILFGTMGPPRPLSATGDKPMSNPVSPAMGSDASPAFPPPPPPMPATGASPAPPGPAPEAPSAPPPPPMPASPAPGGPPPPPPPPPGMGAPPPPPPPPPAGDAPSGPPAGGRPAGLLGEIQLGKALKKTETRDKSGAATAGRVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQB4</accession>
    <name>A0AAD8XQB4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_646070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371624.1">
        <property type="nucleotide sequence ID" value="XM_060509914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQB4"/>
    <dbReference type="GeneID" id="85393813"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042178195" evidence="2">
        <location>
            <begin position="18"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="32640" checksum="57862C85FDBC4456" modified="2024-05-29" version="1">MRYSTLTVLGLAAIARATWDGQFSYPPGIEPLGLANGNADFNIKTFGPLTGPPSDCISVWHPPHPDVYIDDCDSDKEHGWHWVHPGKPKWGKPGKDKDGHKWKKPKHTKEPGCDKCSPETTEPPSAPEPTETPDQPDQPEQPEPTTTPQSWKWTTSTITQTAVSTIYSCPPSVPNCPGDGSGGGTMYETVTVPAVVTICPVPVAPNPGPTTAPVAPPATTAPAEQPAPSNPSPPETLSSVVIPPVSSNPPVVPVPPVSSAPPAATTTKPDSVGTVTRPNPTATTSRAVVTAGAVQNVQRAGGVVVAVVAAAAAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZK3</accession>
    <name>A0AAD9CZK3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_568852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369453.1">
        <property type="nucleotide sequence ID" value="XM_060504123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZK3"/>
    <dbReference type="GeneID" id="85388022"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF2">
        <property type="entry name" value="WW DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06520)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="38851" checksum="C5D3E141ABF57796" modified="2024-05-29" version="1" fragment="single">KILRNVSNDMDLFTITGQGWHFVKYLGPAVCVVGPDCRSERNQARVMAGPTYQGIFPKVATLPPSVQHCIWMVSVPLLYPRLEAVESLAGAVATGKKVVNTSYNILGKVTSSVAGVVGGKDVVAQGFTQVKKAVGKSGLMGNVLNQFGEIDIAEILKDMWTHDSKDLERTYFIRTLQGISQQKGIRMTFLSGDVNCAGAGLVHDPTHPSDHKTMYQVITSPIVAQPASNYILKLLHNNKSLYVPQNGHKSNHEVSDSKEDMMEIFHTDASGSARELKKLMGRRNYVAVVAYDPETVAGGPGGVGGSQYAGSIINGGQQQQQQQGLQKLSLAVDFVVQGDGAFTAPTKYGPVIVPHLEFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D058</accession>
    <name>A0AAD9D058_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_788715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369767.1">
        <property type="nucleotide sequence ID" value="XM_060515684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D058"/>
    <dbReference type="GeneID" id="85399582"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028115">
        <property type="entry name" value="DUF4484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018626">
        <property type="entry name" value="LCHN/Anr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053056">
        <property type="entry name" value="Lipid_Metab_Assoc_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153:SF1">
        <property type="entry name" value="DUF4484 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28153">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09804">
        <property type="entry name" value="DENND11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14831">
        <property type="entry name" value="DUF4484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4484" evidence="2">
        <location>
            <begin position="425"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="617" mass="67746" checksum="A91CCB3AC53F57D7" modified="2024-05-29" version="1">MPSRREPPPLSVRLPTGNAQPELPPISALFLIDFDVKAGYTIVWKQSAPGIELEGLVEYKSLPSGLHTVPDDLIYFVHEGEHAGLSAFINTPCDEEEARHARMIAVGVLVPLSYGRLGRAWRHAEGLKDIASKLAQDRKNTSLLDDYWENNKAKEGAEQERPPMESPSISFSSQAAQPKKSNHNRNRSASDGASLLPTGHRLSPYHPAWSLMTLLDTFGPLIFPIHRAALLRRRILISCHAPVREICNFVYNISVLSNIPQTVAELLAPTSSSQRLRPLFTIGVHDIPFLMEDFEASKRRKVDSNDDLADEAGSGWVACTTDSILAMKDTLWDMLITMPPPYAPNAKEKAWPTVECPRGTPVKATQRDLRRFRALKAGLARLSPTTPKPIMAESPRSETSTSFKLTTGAFPASSVEGDEALDKIVEPSSWTALAYSGFMWWASAGEQARSEEQEEAAHDAALLADLGLTPHTPSMSKPNTRPRSSASGGMADSTGSLVSRPAAGSETDEATTELAVIAYFHRLTAQMLTVMADVVESSDDRYEDEDDEDDADDVPLGTNSESDRSSVRVGSDALESMGLDVWNTHDAEFVRELMSKYYDRRPYIEGKGVEVCGVRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D069</accession>
    <name>A0AAD9D069_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dual-specificity kinase</fullName>
            <ecNumber evidence="1">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_748115</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369783.1">
        <property type="nucleotide sequence ID" value="XM_060513565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D069"/>
    <dbReference type="GeneID" id="85397463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000612">
        <property type="entry name" value="Serine/threonine-protein kinase AFC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="340"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="73"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="172"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="248"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="709" mass="79344" checksum="FFBE8ACDFFAC4266" modified="2024-05-29" version="1">MSTPTTATATLPPHSHYHHPHYPYSHQPYQASTATGSSYRQPANPILSTSSSTATTRLPPAYANSSSIAYSTTSTASHAGPNGLGPSASSASSRTIHDVSSPDANYSLTTNSTMPATSSLSQSSQSARKRRRSKEPDWNKFYKNGLPKEIIVIDDTPEPEQGKAVGNGVRVVSNGNGSVNGATTNGASSRPVPKKRKRDDEPQHYDPVYHNKYAGSHTTTPHHNGTPSGSTISTDRTTNSAIHTTAATSLSSTGHEYYDAQPGQKRKRTRQQIAQEAKKREVEGLGDPFLTYKPPPYPPKKAPDVHVRLVQDQGYNKNAKVDDDDGHYIVVPDADLTDKYQMVKLLGQGTFGKVVQARDRKRNKSVAIKIIRSVQKYRDASRIELRVLATLKANDDENRNRCIHLRDCFDYRGHICIVMDLLGQSVFDFLKSNSFVPFPNSQIQSFARQLFTSVAFLHDLNLIHTDLKPENILLCDSAYQTFTYNRKIPSSSTTVNRQANQRRVLLDTEIRLIDFGSATFQDEYHSSVVSTRHYRAPEIILGLGWSFPCDIWSIGCILVEFFTGDALFQTHDNLEHLAMMEMVVGQRIDSSLVQAVNKMATRSGGNPASKYFKRLKLDYPTPETTRASKRFVKAMRRLEDIIPSNSTYFKNFLDLLRKIFVYDPQHRITAKQALQHPWFKEPATPDDGTEAAKIRLERMRQEGDHRYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0B5</accession>
    <name>A0AAD9D0B5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_727319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369320.1">
        <property type="nucleotide sequence ID" value="XM_060512781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0B5"/>
    <dbReference type="GeneID" id="85396679"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="29827" checksum="520F503589FA9CBC" modified="2024-05-29" version="1">MRHRHWSGFGFITRSHCAQASSRPSAFRPREIRFECLRTLCTAEIHAAIRRCNLQIARCRRSSAWGHARKLLAFAIAFVPSGKRIRVLHTQESMYPTWFDKTTNVPTLTSLCQEYQSETVVHDLDMAKDRRPKDLKITSLTVIPPLDAWYPWLGYVSSRHLRQTATTALPAGRICMLICLVTVSDECPPHSLSPPCGSGQSTLIPKFVPVASFARHWHAFNHCAGVRFTWLSYPRVRGRDEFVLARGFVPAETVVVSGPWLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0D2</accession>
    <name>A0AAD9D0D2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal S13/S15 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_748402</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369350.1">
        <property type="nucleotide sequence ID" value="XM_060513610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0D2"/>
    <dbReference type="GeneID" id="85397508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.130:FF:000001">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="16882" checksum="76C060955855FB4A" modified="2024-05-29" version="1">MGRLHSKGKGISASAIPYSRNPPSWLKTTPEQVVDQICKLAKKGATPSQIGVILRDSHGVAQVRVVTGNRILRILKSSGLAPDIPEDLYMLIKKAVAVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTVGVLPPTWRYESATASTIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Q8</accession>
    <name>A0AAD9D0Q8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_748203</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">TFIIA is a heterodimer composed of the large TOA1 and the small TOA2 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369486.1">
        <property type="nucleotide sequence ID" value="XM_060513578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Q8"/>
    <dbReference type="GeneID" id="85397476"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.18.10:FF:000003">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="11">
        <location>
            <begin position="65"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00063181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="115" mass="12856" checksum="D334C6E5B9942D81" modified="2024-05-29" version="1">MAAAPQSFYELYRRSSIGLALTDMLDDLISEERIHPQLAMKILANFDQAITEALQKSVKARLTFKGSLSTYRFCDEVWTFLIKNVQFKLDNGGQIVTADKVKIVSCNAKKPGEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1C6</accession>
    <name>A0AAD9D1C6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_647626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369741.1">
        <property type="nucleotide sequence ID" value="XM_060510102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1C6"/>
    <dbReference type="GeneID" id="85394001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="32180" checksum="6C4CD3CBDD3477D4" modified="2024-05-29" version="1">MASDSPQAASPRKAEPEQSTPADDASDLKQEPTENENDSKSTSSKGDNDDNSKRDSSSPESGEASSIGSPAPADARDDNPTSSTDAPPLPNEAPPLPAGAPPATQDDGWDFQWDPTAQAYYFYNRITGASQWDNPRVPTAGGATPAAAAPGAPGTTASATATLSGPPPLPKNDAPPAGGYNPAIHGDYDPNAWYAKGSAADEDETAQTSASAINGGEYGAMAQFNRFTGQFQTLDDGPDRHTDEAKSRRQMNAFFDVDAAANSHNGRSLKAERSGKKPSKSELKQFKEKRRAKKEEKRRAWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1Q3</accession>
    <name>A0AAD9D1Q3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_603939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369966.1">
        <property type="nucleotide sequence ID" value="XM_060507253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1Q3"/>
    <dbReference type="GeneID" id="85391152"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="73" mass="7704" checksum="5EE0CB495271F78A" modified="2024-05-29" version="1">MATPPLVAGEYGTSEWASGYSNEDTPLEVGSGEGWSLIQKGLFGGVVVAAIVAYIKFSKSRTARDVGYEKTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2T3</accession>
    <name>A0AAD9D2T3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_746134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371762.1">
        <property type="nucleotide sequence ID" value="XM_060513212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2T3"/>
    <dbReference type="GeneID" id="85397110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="58" mass="5763" checksum="56F7262BD58F680C" modified="2024-05-29" version="1">MSSSPGRAAAAFAQAAAFITVAGKLAVSSTLRRAWALVQWLAAPSGTMLVGCDALAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D313</accession>
    <name>A0AAD9D313_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NAD(P)H-dependent D-xylose reductase xyl1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_564495</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-xylose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371987.1">
        <property type="nucleotide sequence ID" value="XM_060503645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D313"/>
    <dbReference type="GeneID" id="85387544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032866">
        <property type="term" value="F:D-xylose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042843">
        <property type="term" value="P:D-xylose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19115">
        <property type="entry name" value="AKR_AKR2D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044487">
        <property type="entry name" value="AKR2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="10">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="36596" checksum="A444176972147D4E" modified="2024-05-29" version="1">MAVPNIKLNSGFEMPQVGFGLWKVDNDIAADTVYEAIKAGYRLFDGACDYGNEVECGQGVARAIKEGLVKREELFIVSKLWNTFHDGERVEPIVKKQLADWGVDYFDLYLIHFPVALEYVDPSVRYPPGWHYDGKSEIRPSKASIQETWTAMESLVEHKLSKSIGVSNFQGQLLYDLLRYAKIPPATLQIEHHPYLVQPDLIKLAANEGIAVTAYSSFGPASFKEFNMEHATDFVPLFEEPTVTAIAKKHNKEPSQVLLRWATQRGLAVIPKTSRKHVLAQNLSVTDFDLEQSEIDKISSLDRKTRFNQPANYFPTEKLWIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D387</accession>
    <name>A0AAD9D387_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_746641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371286.1">
        <property type="nucleotide sequence ID" value="XM_060513299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D387"/>
    <dbReference type="GeneID" id="85397197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34724">
        <property type="entry name" value="OS12G0596101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34724:SF2">
        <property type="entry name" value="OS12G0596101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="82" mass="8614" checksum="1F7C7CA0AD068CEC" modified="2024-05-29" version="1">MCFGVTCSTCSKATWRGCGQHIPSALSSVPEDQWCTCTPKVTVNGKEYPPAGTVSIPGMSWLTGLFGGNSNDKSKQGTKGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6F5</accession>
    <name>A0AAD8U6F5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000295">
        <property type="protein sequence ID" value="KAK1702951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357213.1">
        <property type="nucleotide sequence ID" value="XM_060506797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6F5"/>
    <dbReference type="GeneID" id="85390696"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="440" mass="48485" checksum="9814C78EA5937A9C" modified="2024-05-29" version="1">MSPPKIPSEHVYCIQTGKKHHELFTTIYLEANYCGRCGLANPFRSEHRARSRTPALPGPHDEVVEVDDSPPRPVRPVSPASQLFRDKPNPVSLIGFGRPAQLLPNELSISGAVHTRARVQPAEALGDPPFMTVATAASRAIQSTKASTRKPTRQRTGYQWVHISLLLVSLEVRYFNGLAVEVPETVLPLKDTVIKFSSTDLLTWPSFTATLFDHLRPLPSTVDPTNKELWSISYASSFSGKKIVTVPNIDKYPGPSAMLAPGHFGNNQAGQLKVLLVLTSTDVIDKQESVTPLRPEEYPTPVKEEKKRRVKQENTSPAPQRQKRVKHEDKSSSEGISGGTDPNRLVSAGVISSPKVPIYNGCRQDSMGDEREEIMEEIVVSEDVEDFCGLKEPLGQVPLDRMVGHSEARGLVHDGDNADENEDGKTAVTKFVRNQVLSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6J6</accession>
    <name>A0AAD8U6J6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000349">
        <property type="protein sequence ID" value="KAK1701645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357029.1">
        <property type="nucleotide sequence ID" value="XM_060515137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6J6"/>
    <dbReference type="GeneID" id="85399035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="210" mass="23351" checksum="19A81547C5589221" modified="2024-05-29" version="1">MCQETEILIVCCTENCLSEKNGIRLPLLRLTPTPEPLYYLCEKAKEMGYRTNGTLLGLPLMTIYPDECPDVASANTFQLCLSHAVSRKTSQRAGFLIQCKECCNAGHAQNHTLSDRPGNFPEFHNRPRTLTAESSTESSTESPPKEKYFTSDWTCCAVGECSDDELCEYRVAAILCGMSTQSQEAEREIIDTCNQETDAGYDGDVSDNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6Y9</accession>
    <name>A0AAD8U6Y9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_143881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358572.1">
        <property type="nucleotide sequence ID" value="XM_060501290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6Y9"/>
    <dbReference type="GeneID" id="85385189"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="113"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1709438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="37047" checksum="5C8B493DAD585434" modified="2024-05-29" version="1">MGPGFSLLGMVAGILSILYYAKQTQRMTGLKFDTEFWAVAGPLIAIRPPKGPTNALELRASVNAGLSAILKDALPEGITEIKHAVKSFDGETITLHQFTPSGNETTSKQPAFIYVHGGGIVGGNIDPHSRPLAAKSALESGVQMFAIEYRLAPEFPFPTPAEDCYAALKWLSEHANDLNIDASRIGFYALSAGGGIAVGASMLARDRGLSPPLAKQILIYPMLDDRTRVETNSPLSKFLTWTDKSNQIGWNAYLEGKAGGSGIPPHAAPGRATDVANLPYTYIDVGGVDLFCAEAVAFANKLASANVQMELHVYPGLPHIFDLYAPTIELTRLARQNRLRAVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U740</accession>
    <name>A0AAD8U740_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_657217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358662.1">
        <property type="nucleotide sequence ID" value="XM_060510947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U740"/>
    <dbReference type="GeneID" id="85394846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1709751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="49190" checksum="66C184F7FCDF3148" modified="2024-05-29" version="1">MEVWSEDSYQVLTASSSSLNVVARYDLPIAHRDAPSSTITAQTTASESTFLTLPRELVADETRGLALRTNIITSSTATSEELRIRALHFHILVKDLDSSQEYLFYRAGYTIPEIVRDRLKLTYPQFAPLLEDLRKKHERIDTLKRRGPFGQAPSQFRMFCKEALAASSIVDVPLSEIHYTWTDVKGLNFHVDTEPHDALGIAECSVHHWVIPSNEVLDDMASCLDVDINDSCRLAGAMTTKDRSNYRFSAAAAAICFLPSMPEELRGHLRRIILDEDRQAVAKQQCHALGLIPFCKENPGLRIERRVNLWLLDGQPPPPQLCTEMFQMTIQRDVAWQAAWFVSMDQGIIPPTEWFLTRSTMSNKLRVARRTEYFYQGFPRAMRDIIQGKSIVKCNFDPSELWNVDRIVQDHLAWTPQQWQEAWADHEPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Z7</accession>
    <name>A0AAD8U8Z7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_686508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000294">
        <property type="protein sequence ID" value="KAK1703021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357217.1">
        <property type="nucleotide sequence ID" value="XM_060511266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Z7"/>
    <dbReference type="GeneID" id="85395165"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="470" mass="52282" checksum="7E1700572F185CE0" modified="2024-05-29" version="1">MAESTPSEDGTFEDVSITSSQESLRQFEDDFSGSHDSRREIVKRLHYTINLPLVSEKRMKKLQSAREAAANNAAFTHAIVDLFRSLSDWETGDITLVIRVASPSDTDEDLFDSLTSSHSGSPIWDVRNDFKYISFDQTSDTKSGLAQVRAISSVDFREDFSNVKRRLDPACISTISQVLPNVNALTWDCIMPSRRLESLRKETRLALAETLKHGAFTNLKNLDIYLEDPDPLNESSDPGAFCASPEEDALSLAISRILQLPAIVNVQLTGLWTIAPAAFEAATDFGSLLEAVYIEGSGTTPDGKWLSIGEEDDVDQDEPDSDSDASEAAFDSADSDTSDFVPEHEWEREAGNFPMNSWRTSIDTEVLVPHILPLVRTTLKMSPLRTLKYEIQTQPSPFFVEYYAPGVENISAKRESNLRGDFERDNVSRSRWFLTVVQGFDPSWKVPPDLISAIEETGGCISWDGPSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U959</accession>
    <name>A0AAD8U959_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_240136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000291">
        <property type="protein sequence ID" value="KAK1703150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357230.1">
        <property type="nucleotide sequence ID" value="XM_060501867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U959"/>
    <dbReference type="GeneID" id="85385766"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1703150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17451" checksum="E71E27479F136CD4" modified="2024-05-29" version="1">MSFIKRERHVPTRIETDVLLTSETPVPLPEVPPRQKWPPILLPQSQTPITPNTVSPDSASIAQLESCLEEVAYGAWLKLAVGSSSSNGYCYSRAKRTLNGCILSQKKPRYLVGESSAKNLARRACCAPVSTRSFVLYSFVLESYFRTSLLLSGEEETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA81</accession>
    <name>A0AAD8UA81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360316.1">
        <property type="nucleotide sequence ID" value="XM_060509183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA81"/>
    <dbReference type="GeneID" id="85393082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465:SF1">
        <property type="entry name" value="DNA LIGASE D 3'-PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39465">
        <property type="entry name" value="DNA LIGASE D, 3'-PHOSPHOESTERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="27601" checksum="53C02697737F9820" modified="2024-05-29" version="1">MTEQEKLARAFGERKIRVRLHGSRLPERYVLNLRLTKGEDAKGRRKSARTMGRPMRKRRRGGGGKQMKKEVVETSSEGASGDDGDGDVVPDPLDGGHDGGDGDGEGEDEKLSAVEREIREVEDEFVRRTNAYRGAENSVGSVYQRRWYLSLDREACGFERRSIGGKRVWVLRHGNDGGDVNGQGIKECGGRKKEEVDESGRLRFPFYVRGPDVERSVVTGRRGGEVLRDEGVEGFVRRKGWRPVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB41</accession>
    <name>A0AAD8UB41_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358544.1">
        <property type="nucleotide sequence ID" value="XM_060509555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB41"/>
    <dbReference type="GeneID" id="85393454"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="8895" checksum="ACD64CCF617BAB24" modified="2024-05-29" version="1">MTQSKADKISEVQSNLPLPEQPPVASDWQSADATKVNVGSGGDAETTVGTGTGATSGLRGPASKANEDLSNVGRQATEGLSGVPKDAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB97</accession>
    <name>A0AAD8UB97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynamin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_657443</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000190">
        <property type="protein sequence ID" value="KAK1708880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358398.1">
        <property type="nucleotide sequence ID" value="XM_060510960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB97"/>
    <dbReference type="GeneID" id="85394859"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056024">
        <property type="entry name" value="DUF7605"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36681:SF3">
        <property type="entry name" value="NUCLEAR GTPASE, GERMINAL CENTER-ASSOCIATED, TANDEM DUPLICATE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24564">
        <property type="entry name" value="DUF7605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="3">
        <location>
            <begin position="169"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7605" evidence="4">
        <location>
            <begin position="806"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1045"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1708880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1108" mass="122393" checksum="5243C93439E9062C" modified="2024-05-29" version="1">MPRIKMESVKAEPPNANLHELPRVPDTVLQQSAAITNPSASTAAPSLETAQPNDSLPHVKPGPGSAAVVKKEQANPILSPANQANKSRISVEEPEQSATQEEIPNFLEQWTTETSPEILERGVKIGLEVLGSLKVPLSLTASLPGTQAMTWVRAIEDLKARSRPSKTIVGVVGNTGAGKSSVINALLDEERLLPTNCLRACTASPTEISYNDSENPGELYRSEIDGNISRECANEDSEAGIAYAKIKSVYPNKTREMIAQSDPDRLVNEPAVARVLGSVKKLRATTAKDLYASMQRYVDSKEKNPHKKDVPMEFWPLIKVVRIFTKANALSTGAVIVDLPGVQDSNAARAAVAQNYMKACTGLWIVAPINRAVDDKTAKSLLGDSFKRQLKYDGIYSAVTFICSKTDDISVTEAAESLDIESDISASWSKIEKLRGELRELKRKLNDAREEKSDLVDGLEQIDTLWDKWDDLANKHADGQTVFAPSESKKRKRGATSSKSRKRKSSYSSSSESDDSDYNSDSDKENHPDSQNRQPLTENKIHGKLADLKNHKKRIRQRRKEVDAVLSNMRQEIKNIQAEEERLLGAAKAVCIQGRNNYSKGAIQRDFAMGIKELDQETAIEEDEETFNPDEDIRDYDEVARNLPVFCVSSRAYQKMRGRLQKDDFNNDGFRDVNETEVPQLQQHAKKLTEGGRAAGGRRFLTELSQLLNSMKMWAANDGSRSHLSQRELQSEGTRVRVQLATLDNLILTLQSLTDTRQDFAKAVDDCIVSVKDALSESIYDYFDLSIPMAASAAGPTASGWGAHRSEGGMFWATYKATCRRSGVYSGVSGPRDFNAELLEPISRQLASGWERAFQRRLPSAFEGFAMNARLLLEGFHGSVIARSQELGADYNGINMLSTQLRAHTARLREIPGTLRTVVQELQREASRGFHPVVQQEMQPAYDICVAESGPGSYARMKNHMVSHVEASRDTIFRHSTDSVKEQLEALCRRLQDELTAHVQDIYSLLARDYLHVLIGVDKDPKPTGLPRAERLLRAEMYRKLEQTAKRFARPSQDASADAANTTGGGDGDDPFADSAIADMDDLLLAQLCGDTVQGADARGTVKNEPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBU2</accession>
    <name>A0AAD8UBU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_756417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360152.1">
        <property type="nucleotide sequence ID" value="XM_060514742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBU2"/>
    <dbReference type="GeneID" id="85398640"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF131">
        <property type="entry name" value="GTPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="145"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="825"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="563"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="882"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1715009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="949" mass="107126" checksum="75FDBD14579CF954" modified="2024-05-29" version="1">MTKARASRGHTVKPEPGNHQNTSPTPSLTNTYNGSPEANRNQSRSYHAGPADVNQSFLRSDAPTPSIAPHGAYTAPQTVRSALTNPTFDESEPVLLQVRNRDMDPPAIPMQNDSFLDGSFRDIGAKVKIFNDTLGELQQLGVSHDVALPQLVLVGDQSAGKSSLMSGLAGLNLPRSEGVCTRCPVHIRVSRSGPRDRGGPQWSCRVSLQQDYAFRPPNHFLTKADVTPENPFPPWVKQARVVKEFMTIYDQSDIDTVLKWAQIAILNHDQNHELYVPGSGAITKQSLLDDEAERTLAKFSPNTVALEIKGPDLPDLSFYDMPGIFRNAAREEDEYLVSVVENLAREYISHSEALIIWAVPMNVDPETSSTLSIIRVLQAQQRTIGVMTKADLLPEGNNTQWLSMLRGEAHKIGHEFFITSRPSNQKLDEQQRWEEGFFHQDASERWPEEFHPFRERCGVEKLKIALSEKLGKEFAKNLPSIKNKVQTRLSEIEAELSTLPELPNNVELEVRKSLMAFSSTVKETLRGRKFSSNYGSLSDSFRDCILQMKPKFILKDKSDIPVLEISDDDDDSSSVTPSNRKRGGYGQHHSAAKRARPTPVNGGNSFSAAIKTEDSVPAPSTPSRRGPPQPMPLAPPFQRYANYGAGFRTLAQIREDIKAKTKAGMPSIVPDEVYEDLCKQAVKAWNQPMETFLQETMNVLQRIVDYALSQAFGSLMKRLIFKKSTNLMNEFLRERRSEAMSFLKDIYDMETFQLFTVNQKAFQDYERSESRVLTRYRHVMRWQAFSGDSYEFHDWDHMTPEQRMNEERKHNVELGKMGPDTFDKELRVAAYVRGYYMLSALRFADTVCLSVTSRMMPKIVQDLDFFLENNLGLIGRHDETVFARLMEEDEATARKRERLKNELEKFKKALDSITTNELEGAFGSSSQGRDAFEAYGESFAETMDLDGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCR6</accession>
    <name>A0AAD8UCR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity methionine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_590653</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359163.1">
        <property type="nucleotide sequence ID" value="XM_060506354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCR6"/>
    <dbReference type="GeneID" id="85390253"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="604" mass="65774" checksum="64BA0F99278AD621" modified="2024-05-29" version="1">MAWRRPFGDRASAQGTVVGGQREQISNGSTQYVGEKGGNDAPPTYQDASGAPVENNSPLGYDVGPVTITLLNITMMIGAGIYSTPASILNGTGSVGVSFIYWTLGYLLCLASGAVYLEFTAYFPSRSGSEVVFLEQAFPRPMWLFPTTFAVQSVILSFGSANATVMANYLIAISGHEGTNWQIKGTALACYSLATLTLVFNTKYAYWFSNGVGIVKICTLLFVIITGFVVLGGGTRVENPTANFQDAWSGSKTASAYGMTTALYRIIFSFGGYNNAFNVANEVKNPVRSLKIYATAALTTVYILYMFANVAFFAAVPRELLEKSGLTVASLFFTQVFGNSGNVRGLNFLIALASFGNMIAVIIGLSRRIRECGRQGVLPYTRFWVSTKPFGTPLGPYLVIWSLTALMILAVPAGDAFTFVNDLGVFPTAAFNLAMAVGIYVVRWRRRKANLPEPEFKAWHVVIIFNICIQLYLLIMPWYPPAGGQYAGDVSFWYATYAVTGVGILLVCAAYYWLWASLLPKWRGYKLRQELVSFDDGAQSNQLRKIPNAELSEWDSTHDASGRLIGTSADEVLVQEKGVRVSSEGSNSDTGKQVPNVVREAHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCY1</accession>
    <name>A0AAD8UCY1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_630831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361872.1">
        <property type="nucleotide sequence ID" value="XM_060508857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCY1"/>
    <dbReference type="GeneID" id="85392756"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042224710" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20456" checksum="0040560C2B7597A8" modified="2024-05-29" version="1">MRVPQLILSLFLLFTFVVALPVPAPVDALVERAQSASKKGSAAGRKKEAAGIDKNINIQKQEQKDVKKVQKAEGTKDFKKQSGQLNKDIAKGQKQREKNQKNADPKNKPLNDGLKKVQGAQAKEAKQAKGLKGNNSKQDKATLNKLSGEFKGGEQQNKKNKQALNGGKGGKKGGKRDVEEAEEIEVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDK1</accession>
    <name>A0AAD8UDK1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_590037</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359434.1">
        <property type="nucleotide sequence ID" value="XM_060506292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDK1"/>
    <dbReference type="GeneID" id="85390191"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000056">
        <property type="entry name" value="CCR4-NOT core complex subunit Caf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="435"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1712577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="54243" checksum="D3E9D5D37FA74874" modified="2024-05-29" version="1">MPPQLPRFPGGPNTISPYHQQFPSHAQGHGPNHGPPLGGNPSYLNTNAAQISPFSTNGNVLGGTPGLNGGFPLGADTGLGSHAARMGFAHAASLQQQQQHGQPQHNFGLDHGAAPARTTQNKGRIREVWKHNLHEEMAVLRELVDKYPYIAMDTEFPGVVSRPMGSFRGKSDYHYQCLRTNVDMLKVIQIGLTLFNEDGETPPARPNSQQDIELSAAQRRAASQGPFPYAWQFNFKFSVKDDMYNEKSIESLSSAGIDFASLERDGIDPHEFASLLIPSGLVCFDNVKWISFHGGYDFGYLTKLLTCNDLPNDESDFDQVMKLYFPSAYDVKHLMKHAIRLHNSGLLTPSDPSSADILQKFEHKSGLENIADSLKIKRVGNAHQAGSDSLLTGKVFFQMRDKIFNGEIPEEHVGKVWGLGIPELLVLERLPFGNNGGNQDSAQNQGPNGQHNGGPSTPNTGSVGLASTPAAQAHNTNGISMGPMTPGGGGGVFGNFAFGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDT8</accession>
    <name>A0AAD8UDT8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358895.1">
        <property type="nucleotide sequence ID" value="XM_060510925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDT8"/>
    <dbReference type="GeneID" id="85394824"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="13956" checksum="98465CF109B89083" modified="2024-05-29" version="1">MKLKYFWNDWPSSRDRGFRVHLSQALVLHLRFPSPPLDVVNLRVNLTTPHFLTVSFGALCSYTPGCDPVDLPANHSSGSRGAKTPAIQTAGLRTLRPHERFLVLVLVLVLVLVLVLSKAESSSPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE22</accession>
    <name>A0AAD8UE22_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_676018</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362517.1">
        <property type="nucleotide sequence ID" value="XM_060511156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE22"/>
    <dbReference type="GeneID" id="85395055"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000722">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF49">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="51"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="53491" checksum="DDEAF7C72B9E9E49" modified="2024-05-29" version="1">MASHPEEKGSFGPGREDVESPAVKEEPSPSSPSSADAEEEKALLWKQDKRIIPLSASIYFLCFLDRSNIGNAKILNSSTGHDMQTETHMSNRDFTIALMIFLIAYAIFEVPSNILLKKLRPSRWLAFLMFSWGSVTIGLGGANSFATVTGVRFLLGVFEAGLFPGLVYYLTFWYKHDERSVRVAMILASATLAGAFGGAIAYGIGHMNQVHGMSGWRWLFILEGIPSCLSAFFVWFFLPDYPESASWLSEREKDLALRRLYHEGSKSSHKTMSWEEAKATLTDWRLYGHYLVYFAMSTPFSSLSLFTPSITSGLGFVDLQAQLMTVPPYAAAYVVQILVAWSADHFNARGVHSAALALIGGVAFAVSAVLPPDAYNARYGCLIIGASGAFACIPPLLGWLTSNIFSTAATGLAIALNVSIGAGLGQIPGVWVYKAEEKARGYPTGHWANAALLFVVVVGCAALRVYYGVKNRGIVRRAAEEGTEPRLYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE58</accession>
    <name>A0AAD8UE58_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_756415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360150.1">
        <property type="nucleotide sequence ID" value="XM_060514741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE58"/>
    <dbReference type="GeneID" id="85398639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1715007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="392" mass="42935" checksum="B1BAC9E14FEE4819" modified="2024-05-29" version="1">MFPDRETVHVVLAAFFGSDWTWANSNVNDMIAMTREAEVCLLGIFHTLAARADLYGALRGHSAFYATVATELKTRGELSGDALKDIEEVYISVKDTIATLPPLQALSLTARPNEMGALTAQFQSASVARPAENKSWPPAHFDPHELALIATPELRGVLFGKTPQTPGALPATPNKATLPLDTRAYLCSLALSNYQPDSTWNLILTPIANFKSQMERRQWAIPSDGQSLYYFSIENALVQAVKIFQHGKAISIALATPWFGRTWGAIPSADEVSGTDTQQGYADGLELIIFDPIARYNHIKNSPQIRASLSSLFAFRQSIRDNTEAAIQGAGGRLIRGWYGGKLEMPANGADSVQLASEWIRLLVLAGGGHVQDPLAVDDEQWEQWGFEEVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEM8</accession>
    <name>A0AAD8UEM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_631826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361603.1">
        <property type="nucleotide sequence ID" value="XM_060508924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEM8"/>
    <dbReference type="GeneID" id="85392823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="56"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="327"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1719519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="440" mass="48639" checksum="E5B20422CC459A08" modified="2024-05-29" version="1">MIESTIQEAVHVAVRELRQEGVYWEPPPILSIVRRSKQARHIPDDFGASTQLSIPHWPDTSKRLASIHLSSGTTGKPKGVELTHYNFVANVMQLVALDHKRQMFNSACRTVAFTPWAHIAMTTAPFFLGPYTGMFHHAMPQYSIEEYGKLVGSTQATMFQGVPSVVLGLANSDVTKRYDFSKAQVINIGGALLKPAQLSRLLSRAPWRLIQAYGMTEAAGYVAYQGFEEVVPDGCTGKLLPGIEAALQKEGTTEDAPQGGPGELWLRGPNITRGYAFNADANREAFPVDGWYNTGDVCRIDEQGRLSIVGRTKELIKYKGFQVSPTELEQILNSHPLVRESGVGALWDESQLTEVPAAWVVLKEDNKNRIKGRNKIIGALKEIQKAVDEQVSGYKKLRGGIWAVDKLPRNATGKILRRDLVRMTEGLCSLEGGRKFVAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEZ0</accession>
    <name>A0AAD8UEZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_655627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360540.1">
        <property type="nucleotide sequence ID" value="XM_060510812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEZ0"/>
    <dbReference type="GeneID" id="85394711"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="3">
        <location>
            <begin position="319"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="64765" checksum="455C6E320AE4EA41" modified="2024-05-29" version="1">MAPLIVNNIEVIQTPTIPPAWPTPKEPSRVELSAGSQKTPEHRPLPCDIILERDQPLTLRDGTRIRVDIFRPKTDEKVPAILMWSPYGKTDTGTLNLHAVPLRCGVPLNPETDLPPRLDPAEWVPKGYAIINADARGCGDSEGDMRSWGTPEGQDGHDAIEGIAKLPWCTSRVAMAGNSWLALCQWYIAAERPPHLTCIAPLEGASDHMRESLCRGGIPSIGFGSMINNVVRGRGHQENSVEMLLKHGQGLRSYWDDKRARMDRIEVPAYILGSYSTMLHTIGSFRGFEEIPHQNKWIVTHATQEWFDLYSQERTNDLQKFFDRYMKGIDNGWENTSPVRLAVLGYSKPPIIDLPFDSLPWLAPSATNTELQRLYLGADKTLRQSNNTDTTTLGYEGTENIVFTHTFTKSTQLLGPTKLVVHVSCPSATDFDVYAQLRKRDASGKDLEHLNIPLEALPVFDTKEVPNINPLKYLGPNGKLRASKRKVAPELSPNYWQTLAHDEDIEVQSGEIVKMEVWIWPTAIQFDAGEQLALKITGSDSLVLPEFEFLAEKPKNAAAQVVHFGGEYENYLEGHWHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF65</accession>
    <name>A0AAD8UF65_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_631131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361847.1">
        <property type="nucleotide sequence ID" value="XM_060508886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF65"/>
    <dbReference type="GeneID" id="85392785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42457" checksum="F983B343C542D85D" modified="2024-05-29" version="1">MAATKTDYQIASLAAGFTIGFGFLTVWEAMKQTRRNRNPLRSTYIYMMWGEIIANLVIAVIGWLFLDGILGPTVPVLFFILFLWVWEIQLLMQIIINRIAVIAESQKTIRMLKWGTAVVITLINIAVFCIWIPSHLDPPISQTYVNINHYWDRLSKILILIVDAGLNWYFLHVVKARLLTQHGLVKYKPLVGFNAKLMVLSIAMDAMLIGLMSLPNQVVYIQFHPVAYMVKLNIEMSMASLITRLAKDQDSGFRFNSLSYSQGHSRGHRTNPTGLDNGHNGHHETGGLKSFHRASVGAVPEDRDLEAIREARTGIHRRVDVEVRVESHSPKSNPASSFSGRHDDAASGSSFYRVDDEDSLTSNPGHPRSSEKKEMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFL6</accession>
    <name>A0AAD8UFL6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_637272</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359840.1">
        <property type="nucleotide sequence ID" value="XM_060509298.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85393197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040848">
        <property type="entry name" value="AAA_lid_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17867">
        <property type="entry name" value="AAA_lid_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="2940"/>
            <end position="3147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2280"/>
            <end position="2843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2332"/>
            <end position="2350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2357"/>
            <end position="2387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2406"/>
            <end position="2421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2433"/>
            <end position="2458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2459"/>
            <end position="2469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2473"/>
            <end position="2504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2505"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2537"/>
            <end position="2579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2589"/>
            <end position="2602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2609"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2668"/>
            <end position="2709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2768"/>
            <end position="2777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2778"/>
            <end position="2806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2821"/>
            <end position="2838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1713787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="3156" mass="352004" checksum="7762BDA6210FC747" modified="2024-05-29" version="1">MQNGEWVLLDEMNLASQSVLEGLNACLDHRGEVYISELDQVFRRHPDFRLFAAQNPHHQGGGRKGLPSSFVNRFIVVYADTFTAEDLLLIAQHNFPTIPTDVVSGVIQFISRLDHQVAIEKAFGAHGSPWEFNLRDILRWLHLVATKDPLLATGKPDDFLDLIIRQRFRSSTDRDEVNKLFAEVFAREPESHSLYHDTNAAFSQVGNALLPRNQTSQPLELPGIDIVPRLPEIESLMICIKQDIPCILSGPSGSGKSVLLEHVAALVGKPLVVFPLNADIDTMDLVGGFEQSDPLREVNATLRELYEGLQITVLTRVPSQVPSSALALLYLLETYRGDTDDLPAIRSAVEQLLAEVSSESDIGALLYTAHSVLRNSLIVSNPRFEWLDGVIVKALEAGQWLVLDNANLCNASALDRLNSLLEPNGFLSINEHCGPNGEPCIIRPHPEFRIFLTVDPRYGELSRAMRNRAVEIHLSERKTQNVNSSGSQVHVESSLQRFSSSKAISFTALSTNDSSDVSHATFGNLSLRDTALMERFSQSLRRGLADASWPGLDKYEGSLNEQLAFLDAADTASLRGAISHLYAKLPGSDSGLREAQPLNPLHNASMARILGRNNDELPFWLSVCYEFLLEVQRCQSAISAQATKAKAVKLASLNRLQRSIVSDRIAAVAKDSTVRVSKFLSRTLQIIKSFIQSNLATAQGWKERAQVIRNMLDFWWRTLHLTTGDLFEEARFQAHLVHGVEAVQKLISSETQSINKQLADRYLQTVEEDFTTGFRLTTGLSMEIMWKRIKPLPIMSEEILKRSQEIERLGIRLDELKWKVKASVSDLARAMSTLVKADQIVRGTDLDATELIQDLSKEIELLETKVGSETSEVKPFFAAEFETLRQASLLKSHAGQYLEAVPYGANDAELTVLSNQNTIGQIRLGSFQSREAHSLTIGQLASQDPGTHVWNGRLATSLLSRLNSIQSTSLRSLGLLETELPALGRSVAALAPVLQKNQIVALNRVIKSLLADVFSLYSDEGDVHCETLYNRINQLFEDNKQDDTLGTVGKVLGLGFGKALQCSDWPQHLPRLVEDHFSTAMLYVVASDRLFENPDETEADEASMMPAFTAMAWSEFANGAIRLYVPDKSFDPQLRPQFEKDVHDELTNQLQHKLSSLLDFETQFTGQQTSLRIQLAEEEVTALGPAPAPAQLLYRPVRSELNYVQTDFNNVLKMVRDQDLYNTHTKFVYLPPGYEPAPEIGLLKQNLALMIDRLANRFHAYQDMTRPLVNLLGCIQVGLSLSTGLITLREQKGYLSPEENLMCLTPFTGGLPYHHGLKKMPNKSLEFLDYTGLIASVEGLSKLSGGIREALFECIHRFYQEWVKKLEEDRKAEEARTNLYRHKGSWEDEEEVDEEEFNELFPTYDQEEEKEKPAIGHQKVRDVSVRLAESHRKVFLEQATPSEALTNVCKKVGNSFAAENKDKYAVLPNMTRRLLPLTLWSIDEQMTTLTANGVSATYNFYTHANLPEVRRLIALVDKVEARFRDLQQVDEIGHMQPLADVRAACDQLLQLTHSEPLAKILPKLEHLHGIVYEWQHGGYAPAIYGAPALYTSLTDTIISWRRLELSTWAKLFDMEAQKCTADADSWFFVAYQVLIATPLSLVDSPELKDYAVNLVRELETYFSTAIIGQFSARLRLLRQLQKHLELLTVDYPSLSVVSDAAINFIGFYSRFEKIVHQTIVKGRAPFEKTMKEVVLLASWKDTNINALRESARKSHLKLFRLVRKFRTLLGQPMKPILDQGIPDEDIPISQDVVAADVIDIKVDPAAIKTCDQGLPGWLAQHKRLSNASKTLSIMADVSAQANQSPLDATQEIISYVKELNTSIAELRKETPSTLTDETKDQVKHLKTRKRNLFADVLKMMRQMGFRYNLGTDELARQESAAVVLAGSPASAVREGSTDDTAEYYFHKVVDIAPKVRASIHEYSGDLTGAEMQRSTGFMEGMMAVLLGQHSSLSSARSAVASLDRAIATVESLKGTTIRHDIDRMPAGLSTSWMKPILDFAIKIVDIHGKLALVDNQPISNILRTALQEFETLSESWSTSASKHNKFTNESHADLQKRYFSVAETLYGELPTSRRDLDFILEQVRGWIHVPNGHARQLPALDATAQKFKHAISSLCDAVLVAVQGYKKAMADLPSSSDDAGWLAKTSTVRSSGLSALHINTIVGKVEDCFSALEVVDLDKDQMGAVASSLFSIVLPILQQYALTCRQSLSQLQNLQAATGYMTFKLAQTFTQLAAKGFCSPQEKSDEQSGDSGKMESGTGLGDGDGAEDISKDIQPDEDLTELAQEPNKEKDGEMEDEKDAVDMADEEMEGEMGSVNGDDEEDKSDGEGEDGEKDEMEEEVGDVDDFDPTAVDEKMWDGDNEEEAEKDQQGEKAKGQKKDEQMAADADANADEHDAEDDNKMDQDDEEEAEDEEPGPEQEDAKFEDDQVKQDQNVEENDALEMPEEMDFDFEEEGEDAGSEEDELDKLSDVEKEDAKEQHESEIEDGEEDTQRPDEKGPEEEDEDGKEEEAPEEDLAGEPELEMEPKAEEEEEETAEQEQPDALAEPPKDNANADANAAPSDVKGGGQDQDVDQMDVENDFNNNAAQRDDGDAGEGSAEQQTSAGKKGQLSRSDDQAQPTDQDQDDSAEEKSRQDPFKKLGDALERWHRQQNDIKDPEKQDGKEDGEQKQPQDTSADLGAREFQHLEDDETAVDAQAMGSASEDQVQPIDEAMAIDEEKEDPQSRVMPEDQDVEMEQDAADKMDTEADEAPKAQDKDGGADKDDGRSGVKTRQGNFDREPSPEEDEVQRDGDEEEEQAIEETSTQLWTTHISEDDNTLPLGDFSEAIQSWTTFQTKTHPLSLSLTSQLRLILTPSQSTKLSGSYRTGKRLNIKKIIPYIASSYKRDKIWMRRAVPTKRSYQILLAVDDSRSMGESSSGNLALESLVMVSRALTMLEVGQVGVLGFGADTFLAHDFASPFASHDAGAKVLQHFHFKQDRTDIALLVRRTIDHFRAARLQNPSRGGGAEDLWQLALILSDGLTPSNQHEPIRRLLREAMEERIMVVFIVMDDTGNKKGDSVLDLKEAKFVKDEHGGSRVVIERYLDTFPFQYYLIVHNLEDLPGALAGLLRTWFAEVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG91</accession>
    <name>A0AAD8UG91_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HCO3 transporter family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_633170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000103">
        <property type="protein sequence ID" value="KAK1718139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361139.1">
        <property type="nucleotide sequence ID" value="XM_060509013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG91"/>
    <dbReference type="GeneID" id="85392912"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080139">
        <property type="term" value="F:borate efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005452">
        <property type="term" value="F:solute:inorganic anion antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011531">
        <property type="entry name" value="HCO3_transpt-like_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003020">
        <property type="entry name" value="HCO3_transpt_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453">
        <property type="entry name" value="ANION EXCHANGE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11453:SF82">
        <property type="entry name" value="BORON TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00955">
        <property type="entry name" value="HCO3_cotransp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="98"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Bicarbonate transporter-like transmembrane" evidence="7">
        <location>
            <begin position="271"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="606"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="629"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="643" mass="71768" checksum="BCD646083D0B357A" modified="2024-05-29" version="1">MPPNLSPAGPDEDPGPPAATSPRHHDDVITPVRESHGLISDKTERRFTEKREGQEEVSVHDTSSEGRRNGRQSEDRNDGTSNSNRWRGYIKRDGKLRPFRLLKEDFSNFRLRYLSDWTVFNQLVLASAVYVFFTNILPGITFASDLYVLTGESWGTIEVVFSTGLCGIIFALFSAQPLTILGVTGPFSVLAENIYTLCENSFKIPFLPFMAWSLIHSGWMHFLLAIFNAHDYTMQYVTDFSADIFSLLNSVIYFHKAIRELQRTKVAVSLAAFLYSIIGAAGTCLLAIALSTAVSWKPLFHRYVRMGLTEYAAAISIVFFIGMPYVGDLATLDHNRLEVSTSFRPSSPSREYFFVEFWKLPIGWIFIAIVPGIIITVLFYFDHEISSIICTAKRYGTQKPGGYAWDVMLLGITTIMCGILGIPPANGLLPQAPLHSESLMYTVYEDPPHVAEEVEEEGPGEGPPAKPVQRVHEQRYSAFLQAAGILLFVSPPFQHVLGFTPTSVLAGLFMFMGFQSLSVNPILTRIWQLLTPISELPALPHGASWMGIHCYTLAQIVLTGIVFGVTLTVAAPGFPIIIIILVPVRLFFMNKIWSRQTLRYVDGWATREGKPEDDESDQRREGLVASSETSRRVPDEEKGSKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGA4</accession>
    <name>A0AAD8UGA4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-transferase family III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_761035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360799.1">
        <property type="nucleotide sequence ID" value="XM_060515174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGA4"/>
    <dbReference type="GeneID" id="85399072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052985">
        <property type="entry name" value="CoA-trans_III_biosynth/detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229:SF1">
        <property type="entry name" value="ALPHA METHYLACYL-COA RACEMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229">
        <property type="entry name" value="CAIB/BAIF FAMILY ENZYME (AFU_ORTHOLOGUE AFUA_1G05360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="61498" checksum="96497C886A82A81E" modified="2024-05-29" version="1">MTDSKYSSVAETKQILDLVLSSVQIPAEAEKISKAVQFSATRDLPYFPIPFKETELASALKAIEGGVAGALAATKDGVASGKKVSVSLEKSTAFLIQAYLATVGGYGKLDKEVKQFLKDTDLLQAQSDPYRRMSANLYETKQPGEYYHIHGSLEASTTLGMIGLEPFRPDLKDHSAIVEAIESHVKQFSVDELERMNADKRQAGVPVLKHEDFIKTPHGKTNTTLPPWSVDSLETSTPPAPLLSTSDKRVLSGVKVLELCRIIAGPVIGRILAEYGADVLKITSPNLSDVPFFQVDGNMGKHAADLDLKTEEGRKHFETLLAEADVVLDGYRPGALEKLGYGATALTKLAKERGKGFVYVNENCFGYQGEWCQRPGWQQIADCVSGVAWAQGQFMGLDEPVVPPFPISDYGTGCMGAIAALTGLYNRATQGGSWHGKASLLQYDLLLIKAGKYPEAVQKELRKLAGNDFLALRHSHSVDQISGTALKAMKGYAPELFSSPNVREKWYARRYKAEVEAVSPVVEIEGVEIGFKRASRPNGSDEASWDFGPEEDHRIVAQTNGVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGM4</accession>
    <name>A0AAD8UGM4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_722167</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361410.1">
        <property type="nucleotide sequence ID" value="XM_060512446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGM4"/>
    <dbReference type="GeneID" id="85396344"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="91"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1719326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="25369" checksum="DFDAEF1A8DCA383D" modified="2024-05-29" version="1">MAAEKPDRKEKKDKKRSVSDGAIKKDKKDKKDKKEKKEKLERALDEHLQADVAATTVASGDVTTVVADGLPVVGALVPFAVPLADEKAMKKVMKSIRKAAKNNTLKRGVKEVVKTLRKSPAAGPGNTAFPGVVVIAGDISPMDVISHLPVLCEDHNVPYIFVTSRAELGAAAKTKRPTSVVMVSEKRSAADSKKAEKKESKGGDDDEDDGEDYSEVYAALVKLVQKETAKQSFWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGU7</accession>
    <name>A0AAD8UGU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_793428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363706.1">
        <property type="nucleotide sequence ID" value="XM_060515780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGU7"/>
    <dbReference type="GeneID" id="85399678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="30460" checksum="5E33FDC226B11658" modified="2024-05-29" version="1">MAFSLLSVRSFLIGLALANIKNWHFVWTIRFLRAFVRRLIDTAPSKHLGPRCLFLPAISATRSPLLECDYNMHKSNSTYFTDLDMSRGNISLVLFREPFNPFPGPKHFIMILGGAQCVWRKEIGPYEKYELWTRVLSWDEKWIYLISHFVKADVFLPGEYAMQPGPREKKNKNGGIETKDTQKAVFASSIARYVFKNGRRTVPPEHALSRCGLLPDDEAESAEVERLRLKWLPVAQLKSGWDSVHGLFEPGELALGRYTDLWWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGX9</accession>
    <name>A0AAD8UGX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_706173</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361413.1">
        <property type="nucleotide sequence ID" value="XM_060511524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGX9"/>
    <dbReference type="GeneID" id="85395422"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF112">
        <property type="entry name" value="RNA EXONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="7">
        <location>
            <begin position="438"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="188"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1719329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="669" mass="73710" checksum="9B9D389F6BC56BF4" modified="2024-05-29" version="1">MSFVDLKHIPCPKGEQCTAFMCLFQHKADRDKMAAPSAPALNALGTSAKRSTDTTTDATRDGPRKRLKAAQDVRNPADSTSPPTPVKTTSKQDVTAPRPDDTLSPVARPISPPPLKRPSSSSSSTADSPATTTTTSYSSPVNSASVQKDTPSTPSKTDPPKKIRKAEALNPRLLKSSPAKFEIRFKLVQLLHEQYARLNNELKKTAKDAEEKQLLLTDQDLIWRVLDEEESTAIEKGAIYSNVIKNKIMQYKKMTLLQWKEERVVQRRQTTQKGPHNKATAPPKKIVTGLTPAQEVQLVRQLITPIDGLAAHGYVSSVPAEADIQKAREGLDAAKGWEKCDRCDKRFQMFPGRREEDGALASGGSCTFHWGKTYFPERQMGDRSQQPKRYRCCGQAVGDSAGCHSNAHHVFKASDPKRLASVLNYAETPANPNAPTDRAVGFDCEMCYTVHGLELIRLTATSWPNGEELLDVLVQPIGEILDLNSRYSGVWPEDMASAVPWTAKEEDPTPAQAKKMSSPKKTKKKMKIVSSPEVARDLLFALISPETPLIGHGLENDLNAVRIVHPTVIDTVLLYPHKHGLPYRLGLKMLMDSLLNRKIQVETAGKVQGHDSAEDARAAGDLVRLKLSEEWKSMKLKGWKLEGGEFVPPGGKVDDFNGHLTAEFLESAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH35</accession>
    <name>A0AAD8UH35_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_628324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362792.1">
        <property type="nucleotide sequence ID" value="XM_060508697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH35"/>
    <dbReference type="GeneID" id="85392596"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042064805" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8853" checksum="2BC94ADAD8B8EA14" modified="2024-05-29" version="1">MHESSRTSNLAFLFRMVVLAGLARPVEAFFRACSWCADLPRRLAASHPARMSVWVVSPWCVFVDCGSECFCAVRSSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIB9</accession>
    <name>A0AAD8UIB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycosyl hydrolases family 31-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_779363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364501.1">
        <property type="nucleotide sequence ID" value="XM_060515515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIB9"/>
    <dbReference type="GeneID" id="85399413"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06591">
        <property type="entry name" value="GH31_xylosidase_XylS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="232"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="571"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="673" mass="77254" checksum="1BFD6400C8E8A587" modified="2024-05-29" version="1">MIHQKDGLLIYQYDGEQVWIQPWGPDAFRVRATKAHVMPTEAWALEEEPKQVKSEISLAEGGSATIRNGKARAVVSKRGKITIYNANDVVVLEEYARNRRDLLDAKCSAIEVEAREFKPLRGGDYHLTMRLESQRPDEKIFGMGQYQQPFLDLKGLDLELAHRNSQASVPFALSSLGYGILWNNPSIGRVVFGKNITVFEAYSTNILDYWVVVGDTPADIVQRYASVTGKAPMMPEHGLGFWQCKLRYETQEELLEVAREYRRRELPLDLIVIDFFHWPLQGEWKFDPQYWPDPDAMIQELRDLDVELMVSIWPTVDQRSSNFQEMLEQGFLVRTERGIRTNFEFEGSTVYYDPTSPGARKYVWNKAKQNYFSKGIKTFWLDQAEPEYSVYDFENYRYFLGPNLSVGNIYPKEYARTFFEGQKEAGQENIVNLLRCAWAGSQKYGALVWSGDIASSWGSFRNQLAAGLNMGIAGLPWWTTDIGGFHGGNPENEAFRELFVRWFQWGAFCPVMRLHGDREPKPGGLASSSGAANEVWSYGPAVYDICRKYLFIREKLRDYTRRLMAEAHEHGSPVIRSLFYEFPGDERCWQLGAEQYMYGDAYLCCPVVNPGITEAKVYLPKLGGGEQWTTLPHEGFKEQDFEGGQEIEIQCPLDWMPVFVRKSKAEVVLQKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIP4</accession>
    <name>A0AAD8UIP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_742668</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362475.1">
        <property type="nucleotide sequence ID" value="XM_060513117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIP4"/>
    <dbReference type="GeneID" id="85397015"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28383" checksum="4AC8DC6049ABFC52" modified="2024-05-29" version="1">MGLFDSKLKFPIHMVQLALVIAALSLSVARIFLPNRPRGRSGTMALGMAAKSLIIIAYQVLTEHVSSFKRWASLKANLILNGMEVVFWAAVAYMGIQGNTQQSCMGVSCTIGWIVVVMGILLSIVAGYATIIAWLDFRYFKANGVRRGSMKQTALGSSSDSEAGQSAERIEIQQQSKPQTSSPAPRPAVAPVHFNNSQQSNQYDAPPYGQHYAQQYQQQYQQQYQQQHPQQYQQSQQYHNQYHNQYQYQQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ76</accession>
    <name>A0AAD8UJ76_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362481.1">
        <property type="nucleotide sequence ID" value="XM_060510665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ76"/>
    <dbReference type="GeneID" id="85394564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="121" mass="12873" checksum="2365C19C75408F2E" modified="2024-05-29" version="1">MAPSTARLTIFVFGLSSFAAGVHSILRPHDSLKALDLPAAALPAANGNALAAIAMGIYYTLAAAQDNRAFFLATVPMRLTSAFVFWRQDWGIVSGWEGGSAALTLLALAWDARQQIKTHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJB2</accession>
    <name>A0AAD8UJB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sphingolipid delta(4)-desaturase</fullName>
            <ecNumber evidence="8">1.14.19.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_583392</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:46544"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:31488"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="1.14.19.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.17" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362344.1">
        <property type="nucleotide sequence ID" value="XM_060505653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJB2"/>
    <dbReference type="GeneID" id="85389552"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042284">
        <property type="term" value="F:sphingolipid delta-4 desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03508">
        <property type="entry name" value="Delta4-sphingolipid-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011388">
        <property type="entry name" value="DES1/DES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013866">
        <property type="entry name" value="Sphingolipid_d4-desaturase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879">
        <property type="entry name" value="SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12879:SF8">
        <property type="entry name" value="SPHINGOLIPID DELTA(4)-DESATURASE DES1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08557">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017228">
        <property type="entry name" value="Sphnglp_dlt4_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01269">
        <property type="entry name" value="Lipid_DES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingolipid delta4-desaturase N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="43137" checksum="3805B32261418916" modified="2024-05-29" version="1">MASSAASTVTQPSKRKSAAAPDGVAAGKLTTDAPTETPKEKDFFWTYTEEPHRTRRLAIIKAHPEVTKLCGPEPLTKYVVAGVVAMQIFWAWYLRDTPFFSWKFWLVGYVFGATANQNLFLAIHEISHNLAFRSPLANRLFAIFANLPIGVPYSASFRPYHLTHHKSLGVDGLDTDLPTALEVVFFDSILGKAFFCTFQIFFYAVRPTLVYSVPFTWVHYLNIAVQLAFDFALYSAFGLNTILYFLLSSFLAGSLHPLAGHFIAEHYVYETVTPAQRDAANNIPVPETFSYYGPLNFLTYNVGLHNEHHDFPAVPWTRLPKLRAIASEFYDELPRHESWTYVIWRFILDPNVGITSRVKRKQGGRKVGGGAVANWTREEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJB4</accession>
    <name>A0AAD8UJB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tautomerase cis-CaaD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_785666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361565.1">
        <property type="nucleotide sequence ID" value="XM_060515636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJB4"/>
    <dbReference type="GeneID" id="85399534"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028116">
        <property type="entry name" value="Cis-CaaD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14832">
        <property type="entry name" value="Tautomerase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tautomerase cis-CaaD-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="179" mass="20336" checksum="054BDFB413563814" modified="2024-05-29" version="1">MPFYQIYHTYPLTKKQRESIALSITNLHCSTFSTPAFFVHVNFIKQEPKSDDGTYFMAGKSHTSNSNRIVALVRTSASRTKDDFDALSAKIEDAWNGAVKEPGQEAEFDEAKRLLMVVFTPMLAIREGGMAIPDAGHEEAWLKRQLPYFKEMSEKHGVKDFTDLLEELKQMESLKGLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF0</accession>
    <name>A0AAD8UJF0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Family 43 glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_703204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362895.1">
        <property type="nucleotide sequence ID" value="XM_060511477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF0"/>
    <dbReference type="GeneID" id="85395375"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF8">
        <property type="entry name" value="ARABINOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070706" evidence="1">
        <location>
            <begin position="19"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="36639" checksum="FE3656EBBDE793DB" modified="2024-05-29" version="1">MRFLSILTTVASAAIVAGNPVARQTSNFAGYLISTFSDANPKVQFHLSNGNSASSFKFLNKGQAVLTSTVGTKAVRDVYLTTNPSRSEWYIIATDLDINASGFNWDKATRTGSRGIVVWKSTNLVDWSASTLRIVEADTAGMVWAPSAIWDDAKAHWYVFWSARHYRSTDTAHTGTATLDRIRYTTTKDFVTFSPARDYLALADTPLIDQEFQYLGRSGAYARFLKNETTNQVYQEVTSNGIFGTWNRIPGYVRNESPREGPASYADNTTPGLYHLLLDDYTQYVPFQTSNIQSPNWQAGSTSGFPSGLKHGSVTPLTQAEWNALNSRFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJN3</accession>
    <name>A0AAD8UJN3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_414700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362691.1">
        <property type="nucleotide sequence ID" value="XM_060502938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJN3"/>
    <dbReference type="GeneID" id="85386837"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17480">
        <property type="entry name" value="MFS_SLC40A1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="53708" checksum="284BDF6251FD5B2E" modified="2024-05-29" version="1">MMTYTQPLPDEEAIRPDEQTPLLGTGAGQGDGSVSETHRVDPRIARRLYLSHFLSTWNSRMFEFGAVLYLATIFPGTLLPMSLYALARGLSALVFAPTVGQYIDNNDRLKVVRASIVFQRLAVSASCVLFYVLFIGLPLGDYGRPALLALLSFMACVEKLYSIVNMVSVEKDWVIVIAKGDIEALAVLNAQMRRIDLLCKLLGPLSIALIDGFSTKAAIIVNFSMNTASVAIEYYAIAKIYNEDPDLQELKSKPMSTSETTAASVNPGKKVLGHIKRSVSDFKFYFGHRAFLPSFACSLLYLTVLSFGGQMVTYLVASGFNTTYIGIARTISVVFEVLATWVGPWLVGRIGQVRAGLWMSNCQVLPLIGGLVAFWVFMPNPLISATSLVMGVIISRLGLRGFDLCTQIIVQEEVEAESRGRFSTVEAAWQSAFELLSYMATIIFFRPSQFNWPALVSVAAVTSASLAYTLFVWKRRGHLLHFEKFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJV6</accession>
    <name>A0AAD8UJV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_347439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364648.1">
        <property type="nucleotide sequence ID" value="XM_060502496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJV6"/>
    <dbReference type="GeneID" id="85386395"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="27342" checksum="032EA82F25A76125" modified="2024-05-29" version="1">MPNRSPPTSPPTLLHPTADHRNRTLSAPTKQIAVLILLPKHLTLPLSAIFAVLVPPPPSPQLSFTAGVPCFPSADLPHSAPCFIFFSPKSHGEAHKLRQATQNTLSYQQSFRRKSYGESPVNYIQLHTANRVKYPSQWLKRSRALFPPTSSPPSAVRARAMRSSAPATTARRDPTWYILYPPFSFSAALDGACRVPRPAPALSRDRQNTALCSSRTATPASLCHFFHAEYLKCRTTLGYLLYLDDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL43</accession>
    <name>A0AAD8UL43_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_754291</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362540.1">
        <property type="nucleotide sequence ID" value="XM_060514461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL43"/>
    <dbReference type="GeneID" id="85398359"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="25603" checksum="B8B2D3C1DF94996A" modified="2024-05-29" version="1">MFVALVTGGNAGIGEAVVQQLARIPGFHVIIGSRNLEHGSRLAESLKTGDCSVSSIQLDITSDESIFKAIESIQKTHGKLDVLINNAGILIDTYPDSFSSTRDLFRKTYETNVFGTAVLSEAALPLLRKSEYPRIIFVSSQMGSLKSALDESMPFYNVDYKAYDGSKAAVNILAANYARILKDVGGASNAVCPGLVRTKLTGWMDAGAPTSVGAERIVELAIASPGGPTGTFSNRDGPLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULE9</accession>
    <name>A0AAD8ULE9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Non-ribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_702074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363546.1">
        <property type="nucleotide sequence ID" value="XM_060511450.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85395348"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF16">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHASE ATNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="754"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1829"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2320"/>
            <end position="2347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2320"/>
            <end position="2330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2392" mass="263704" checksum="3EC4BF7E43DE3107" modified="2024-05-29" version="1">MAASVYLGSRTPSRSVEVIFFQYHKFQSLKEQAQCSASSIIRLACAICLQAFSPSERICLAFQGKEKVWQPWSKSISCNDRILPLLQAELDTPQISLPVDEDIFRHALSVSALEEDFQTFENQPPLASLKGVYQDVEMLFTAKWDHFTRGILLKCEYTVSCLSDWQARCILSTFRQVLENIVSNPYSRVAEIELMNDRDYQQCLDWNERSSDHSDISVDKMIDKHIQDSPLSPAVDAWDGQFSYAELHAVSSRVAQELRQRGIGPESTVALFFDKSVWNIVATVAVLKAGGAFVPLDPSQPDNRTSFILERIQAKVVLCSEIYTQHLLHFSQNVLGLGNSWFQVAPSPIPQSASTILPWNLAYVMFTSGSTGEPKGVMIDHSACGASVVAHGQATGFSHNTRTIQYARHTFDASIAEILTTLAFGGCIVVPSTDERLDNITAVIQEKRVNWAFFTPSVLRLLEPLEVPGLTTVVVGGESLGQDIIEAWAAGRNLINGYGPTENTVFSTMHPLSLSSKAGAIGRGVGTLCWITDPEDPNRLSPLGAVGELLLESSQLARGYLSFADNEGPNQAFVRDPPWLAKHGRRSRLYKTGDLCRFDENGVIHFEGRKDTQLKISGQRLEASEVEYHLRAAFRTPDIIVDVLNRPTQDTKAQSKVLVAFVCLQRESDQRPDTASNYIMIRRHPPLLEAIPNVEEEMSQKLPSWMRPSIYIPLFDFPLSPNGKADVKRLRREAASLTAEQFYLFAQTDAIVQVEETPQLCLLRDLWAEVLGIQPVAIVATSSFFRLGGDSLAAISLVNAARRKGLQLSVAQIFKSPSLRDLCLLVTEFKKTMFEVRPFELVNKEGFREVLDEISCECAISTKDIEDVFPCTPLQEGLMALSSSTPNSYLVQYVLDTTVDIDIARLKMAWETVAKAHGMLRVRLVDTISSGILQVIVRENLTWNESFNLEEYLEVDLNVPSTLGVPLNRFGIIYNARGDASHMVWTVHHAVTDGQAVGLTLQSVRDAFHGALKSTQASFASFMKHFKDMHMESASRYWSSVFEGGEFASFPRKPSAVHGALEHQGPAFALRKVPVPSSSTDATATTMLRAAWALVISRFSNSDDVVFGVTSSGRNAPFDNIDSILGPIIATVPLRVRCNGSSTVRDLLDSIQMSTINMIPFEQMGIQNIARINPSCRSACDFQTMMIVQPEVDMAMENGPFVSYHRPQDLDKFRSHAIMFECNLGQHEVFLNVNYDPQSVEAAEMERLVDYFASALEFLASSEHQVLDDFFRNPIAKDLSDIREWNKLPPQMVDTCVHTVFEEHVRNQPDAQAVFAWDGSLTYLELDTMASQLARVLMELGVGPEKMVPYCFEKSMYTVISMLAILKAGGAMVPLDPAHPQDRKAFIVRNTMANVVVASGGNADAFAELDVRTVVVDSNFFAKVEEVGVATFSNHEVEPCNAATVIFTSGSTGQPKGVIQEHKTLCSAANAHSSGMHMSKGSRILQFSAHVFDVSIIEIVNSFVLGACICVPSDEERMNNLAGFISRSQANWAFFTPSFARTLEPKDLPSIKTICMGGEAMTMDCIDTWSEIVQLINAYGPCEGSVCTTANISSGGFKTDSIGHGANTLVWIVDPGNHDILAPIGTVGELLIEGPSIARGYLGDPDKTAKAFITNPAWVTQFETGITVRRLYKTGDLGMLNFDGSISYFGRKDTQIKLRGQRVEPGEVEHQLTQLLSPGSIVAVDALVLSGSSSKSLVAFIQLENNGFGFAEKRDIIEGISGRLTQQLASVLPAYMVPSHLIPVEVIPFTPTGKLDRRTLKEYASNLCIAENPERGMVEEDTDMLAASEHIALNISNKLAELLSVGDSQRAGTLRGHNFNPYYAGMDSIQVISLSTFIRKNYNVSIPIQKYMNSAATIREIAQLVFEDQQGSHDDSTIDLMHKIEVHDRPLAASPLLKSYAEIETLHTPRIILLTGATGFLGNQLLAQILQRPQTQKVLVLVRGQDSVHATERLLSLARGSSWWQEEYVNRIEVWHGDLSLPHFGLPVALWSRLDGTSVSGDLIDAVVHNGAVVNWMADFQALTPANILSTVNILTALTKAIASRPVRLTYVSGGHLSTSPDDVGEIAAELKSYPAYSQTKFVAEILVARYAERLIDAGFGCLATIVKPGLIMGSSSDGISNTDDFLWRLTASALDIGMFNDSERDLWLAAAGVDLVAKAILDSCFYPEINGSHHVVKKVLNGLTMGEYWDIVKQETGHAMEPMDSKRWLRSLHEEVNAKGPSHRLWPVLHFIEDTDGKLGQPQGTMTLDDQLKDQDLVKLSLRKSLGYLLAIGYMQTSRTSSVDGDSSSEPTLSVPRPMVFSRTPTTPVWNQTSTYQKRLGYGEEGLKLAGSMVVTPLRTPSPSSDVVPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULW7</accession>
    <name>A0AAD8ULW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_720310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364008.1">
        <property type="nucleotide sequence ID" value="XM_060512262.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85396160"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="788"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1220"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1325"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1362"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1397"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1436"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1459"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1510"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1561"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1665"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1729"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1739"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1815"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1849"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1945"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1962"/>
            <end position="1974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2002" mass="220145" checksum="72AD93CE6229ACCB" modified="2024-05-29" version="1">MDPTNTGGFASRRPSDFSFFSQPQTSNPDQRQRRNGDAIFSDPTRDFLIDFGSEEGFMQAAKKKKKAPAKAPAANNNNDDDGAKKEDEGAGDGGDQGGDAGNDGGAAGDGDGGDKETPPADDPPPEDDWGFATTKSKKKGKKADEPAPDSFDEIKLDDIGSGNGSLDINFGSTETKKSGGFGWGLGASNWTTTGTGLGNTWDWSGANKNAATSTPAEAKEDVDSNPWGSKSKTKKKSTTLGFSFGDDTPADPEPAPDPPQEKEEKDDPWGFGTATSKKDKKKKKTSIWDAVEEEKAPEPPKEEPPADDPWGSWGGTTKKGKKDDPPKEEPKDDLWDTWGLGKKKKNKDEPAPEPVPELAPDPPASNEDPWSWGTLSGKKKKKGLVDLEPEPPPVADPEPEPTPPPEPEPEPVDPFAGLTNSQKKKKKKEMAAAAAAAEAEAAKAAEAAAAAAEAEAAAAAEAEEAVRKEEEERLAKEAEEQAAKEAAEAEEAAKAAEAAKAAAADDFGWGVSTKTSKKKKKGKADPEPEPVPPPPPPAPEPEPEPEKKDDPWGFGTVTSKKDKKKKKGLLAEPEPPKEPEPEPEPEPVPEPEPEPEKPAEDDFWASLTGSKKDKKKKKGKTTDPEPEPIPEPAPEPPAADPEPEPIADDDWASFGLSKKDKKKKKGKLADPEPEPEIEAEPEPEKKDDDDFWAAATSSKKDKKKKKEAEAEKSKDDSWGIWDKEKEKEKDKDKEKEKKKKSKEADKEAEEPKAEVDEWAGLSKSDKKKKKKDAMALVEFGGEDEPTPAEEAPPAVPDIADPLDGGGFFSSWNIGDKKKKGADADEGASMKPDAIEEPTDDIWGTSSSKKKKDKSKNEPIEVVDEEPTVDSETKDDDDWAAWGSSKKKSKNPPTPPSLDMAEPVAEAEPEKEKSSFWDKDKEKENEKELKKLEKEKKKAEKEEAARLAKEEEEAATAAADAAAKEEEERLAQEAEEAAAAEAAEAAEKARFEEEEAAKIADEEEQFAALEAKKAKKGKLTKKDQGASIDERAAASQAAADAEAAAAAEAEEAARIEEEERLAKEAEEAAAKEAEEQAAREREEAEAAEKKAKKSSKTEKESKSKSKKEKEKEKEKEKEKEKKEKKDKKDKKSKDKEKEKEEEPEPESAPVEDIDNEDELADIELTEDQIEELLADPEPEEAAPPPPPPAPEVKPSNDAFSFWGVGTKKSKKGLEGANLGWNDTTTSSATNNDALSWMQPSTARKGKGNKITDRLKAFEPIPPPEDEPEPVVEEPAPEEPAPEEPAPEDPPPEEPEPAPPTPPPVVLSKEERKRLKKEKKRAAEAAPAPPPPPPPPVVEEPPLVDVEEPADENKSSEPPGAFPVEEDENEIIEVIEMPVEKKKKKSKKNRDRDILAEEVPPPPAPPPPPAVPEAPEDPVPEEEPAPEEEPISPPPEPKSSKKDRAKINREGSSWGMWSASPREKERDRDRERDRDRDRDRKSKSKSERREKKHAYGDEEKVKTSSKGSSSGKGDRADRDVETPARPKLMSMFSTPPISRTTSTRDRRHRPSRRHSVDASGLVSPPPEEAPPPPMSSKAAKVLGVDKSSSRRRKHDHIVDEDIVMVGANGDGEDGSPPKSSRRRSRYAKDDDLVMVDPDGPSEPPPMKRSSSSAKKGLGGLFSGLRTPKTERPDPLRRRHTYATDDDTRRERRQRSHADADEADPAAMTDMDQEARRAARRARRAARNAEAAEAEVVEPDPEEARRAAKEEARRERHHEEDAEQQEKELRRAERRAARSRGHRDQREEEERRMAEDREAERAERRRQREATAAAEADADARRAAREERRRAPAPPPPPMDEEEARRARKEARRAARTDAEEIRRTRESGDEGMHSSRHRYRRNEESKPAWPHSGTSSWVKEHTDAGPPPDDGGQQTDAVPQTEDEARRERRERRRRARYEDGTADEADDRRRRARREERERRTYGGSGGAGGGGGSEGSDERRRQAMFSDATATPRSSWWRKLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM37</accession>
    <name>A0AAD8UM37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_652278</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364364.1">
        <property type="nucleotide sequence ID" value="XM_060510512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM37"/>
    <dbReference type="SMR" id="A0AAD8UM37"/>
    <dbReference type="GeneID" id="85394411"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000010">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1724309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="136" mass="15392" checksum="9AF51E808E698349" modified="2024-05-29" version="1">MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVESYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX3</accession>
    <name>A0AAD8UMX3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cbs domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_577845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364799.1">
        <property type="nucleotide sequence ID" value="XM_060505063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMX3"/>
    <dbReference type="GeneID" id="85388962"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="50610" checksum="CBC62E124E965AC0" modified="2024-05-29" version="1">MAVHTIAENIGDVEEQHLAREDLPRRYLWRIWRLLENRGVCFQAWKVFSKFLLAEDDEKTLGLYRYRQHICQPSGASLRHYLKPLESLNVDFVTHLTITGSCSFGENELLALPKLRNLAILEIIEPASSASVMDEQHAPSFPKVDDRLVRSWSEMDDPFPLLRILRLWGDESVTTHSLQYVSKFPALALYDVNASRLDWRDTWGVAEENGWEVDEPLHGPHDSLLWYLLLFDGAVDTAEGKDGSKPRQLQGMARNIDDGLMNFCQSSNQPITIEASSSGGQDAPPFLDHLSDAAKRNLSMYVDVPGYEAQTCKGFPFETWGFWLYSFLGQLTGDADLKRAGPKTATLLKAVSEQLVLPAKPFACLQLGHCGSGRPGITPAVSYVRRGLFATCRYTFFRRSSGVTKHEPARKPAESLRPKVELGKVETGLNPNRKKRRRLDDILQSFMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMY2</accession>
    <name>A0AAD8UMY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_622890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364563.1">
        <property type="nucleotide sequence ID" value="XM_060508346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMY2"/>
    <dbReference type="GeneID" id="85392245"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="338" mass="38804" checksum="F98B254A5E37A6DC" modified="2024-05-29" version="1">MGLSLDDIYSETLGSSWILFDGASEEQETMLELFHMWLYICGLDQDMEAFFVSEGERYQTKFNVISSFVWKLPEANRIMATRRNIAYYKLPPKSRFACLGWQSIDPQVLLNDIHHGEGLKPAEFSVVFDGPKESSMESFVNAYVNFLFDTDNDHLEYCQPLETHAPAHPWRHLAQWVLRGVAPERLSRKACLDGYSITATTLFALFLHVEECLTFSGHQGWAAKLRMAQLLSSWLEDAELAGLDLGEYGRQESEIFMGCDQLRLRRWFEPIGWDDREDDCEDVTSPSGFRLQSFTYGPHPTDWALLWILDAEEYAGEFWDNIEIPPSVIPGGWVEDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMY9</accession>
    <name>A0AAD8UMY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_624539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364099.1">
        <property type="nucleotide sequence ID" value="XM_060508447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMY9"/>
    <dbReference type="GeneID" id="85392346"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053037">
        <property type="entry name" value="Pericyclase_pydY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38115:SF1">
        <property type="entry name" value="LIPOCALIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="36615" checksum="E513395FBF637E26" modified="2024-05-29" version="1">MPDQAAYKKAPTDWAPSIRSQIPRHLCCSAQLVHSHLLIYSPANLQRREEGGLPETKFVPALNNHFGLTAFHLCEPGLPTYTQCTHLTSADPLTFCLRCNPSDHRPKDIKHRVVLQPTFVAASPKHIRTTHHITMAAPATKTIADLNGKWVMNKTLSDSPEPALALQGIGWMTRKAVGLATVTLDVKQYTAPPSPPGSGTEPVTHFDIDQFATAGLKGTTEKRCVDNEWREHSDWMFGSVRGQSRWMTLAEIEDEFLKKGWLEGDAEATGPDGKAHLYSHVESIDNGWTASQIWGFQTVEGERRYTRNVLVQKGGKRVEIRLVYDYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP40</accession>
    <name>A0AAD8UP40_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_576108</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365745.1">
        <property type="nucleotide sequence ID" value="XM_060504892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP40"/>
    <dbReference type="GeneID" id="85388791"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="58033" checksum="7F98EA71940BC900" modified="2024-05-29" version="1">MSAEGLKAMSDLADAADKSRQKSCNACVRSKRRCDKRTPRCTRCNEKNFSCVYQNLPPASASGRGNSGGGSGSVGVGSLGGRGDSSSSAGGMISNPDDTLQAMDIEEDCGNIDDDLPPFDFNTLTDHHLQHQQHHHQPQPQQQPTPVSSSSYLDGGLPTIVMTEDIHNGIGSGNNSGSNIDNATSVPPTSSLNLDLNAANAPFDFNSVMDFLNADPTAGGELQLWETPLTPIVQKTILPEINQLSPCDWDNEMGEACVTSQGGFQPWQIHEPNSRIGHLVSIVKNMHVVFAQTKQTPFLHRHLYRGVRETPRPLMAAYTAISAYAGMTESNKDWAIRAVCEGANEILKGGAGAGSNITGHEKLARAQALFLIQTVRCFDGDIALRAQAERDMGVLEKWLKDLEGLRDNFDEVHLLDDGALRGRPPRSWEVWIFNECVRRTVLMGYVFTSMYQMLKSAGDFDPDLAPWLIPHRWTFSKHLWDAQSSPTFFTAWREKPMFLVNSFFVQGVAKIMRPADVDDFARMFLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPR6</accession>
    <name>A0AAD8UPR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_572893</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367303.1">
        <property type="nucleotide sequence ID" value="XM_060504564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPR6"/>
    <dbReference type="GeneID" id="85388463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="12"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="412"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="732"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="703"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="712"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="845" mass="93968" checksum="3842E73443D5F923" modified="2024-05-29" version="1">MASSLAPKPRPRPAHTTGTTRLAYTPSGARLVTVGSNNTIRLYRTHHDGEPFNIDDCPEQNCAVAASDAFFVVGSEDGTVSVYSVEDTTFERFLTRTSLPVRDVALSPDAKWCAVASDELTVKVVDTQDNSRIRVLKDHGRPTKHLAFDPKGGLLALACTDGVIYVYSMTAETPELIRKVDGIIGPLDPESENSAKIVWHPDGRAFAVPTPMHDVQVVSKNDWEKQRTFANGHLGDVTAVAWSPNGAMLATAGKDGKLLIWETKTQSVIQKFDYSNVIDITWHPKDNLLSFTTSDGEVYIYPNLITEQFSSFLQLPRQPAPFIHDPLFEISNNARRPDANGKAAIPSRPRRDSLGSLDSFLNGEDGYDDGDGFVVDDDGAGYSTGQKRPLDGGGDDGDRASKRRQLALNFHEAFQPGSTPWRGNRKYLCLNMIGVIWTVDQDGHNTVTVEFYDHEFHRDFHFTDTFLYDKACLTEHGALFSCPPQDNTPATIFYRPHETWTQRTDWRTELPKGEAVVAMSLSESFITVTTTANYVRIFTLFGVPYRVYRPKSTPMVTCASWRDYVITMGNGPVGADGNARLLYTIENIKRDEICQNEDTVALPDGATLQSVFFSDVGDPCIYDSTGTLLTLLHWRKPSRACWVPLLDTKLLPRLASGRKTETYWPIAVADKKFHCIILKGGDQYPYFPRPLLSEFDFSVPLTSAPAPAPDTEGAEGDNGDDEEDEGRRESRKLEQKLLISGIHSAQLRDLIDHTDATHSQKTGLARLELELDKTLLQMLAIECREGEERGMRALELVGLMRDRTGRMVEAAGKVAERYGRSILGDKIREIGERRVSGMDVDDGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ71</accession>
    <name>A0AAD8UQ71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366345.1">
        <property type="nucleotide sequence ID" value="XM_060504735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ71"/>
    <dbReference type="GeneID" id="85388634"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027796">
        <property type="entry name" value="OTT_1508_deam-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14441">
        <property type="entry name" value="OTT_1508_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="505" mass="56117" checksum="DBA41F44A8CF45A5" modified="2024-05-29" version="1">MSLSLSPLLDALPTDFVPESSGLIHPRPTVTASSASSIWRDLPEAVFRQHVVTLEKLTNAVPVDAKSFPLPSQLTTSSDGSAEARAKVLTDGSPETTVTNDRYRQSAEQLKHPRPRLLTVATEQRLADDIAYLVAVGEGAQSVAAATVQESRIKVDVAAGGLDGGPNHDQQALPAASLKVTIASADAIEPTSQAFLRSVFQILSAPPPAKPLHSLLDLVIRHHQARLLNRLRSAKWNKPTYLSRTHKKPLYADFANLIHRAQFLYSKRESTARAGLERELSEMAALLKAFETESDDHEKLVEIAQSSYQLCASPLIANYLERLQAIRATAQIQACLKTLRQLEKIAAYYRICQTLTGLSHTRPMIFNSAKLVFLPPYEAVPLTLAYQPWAKSTHVHAEVILSVHHDLEKSDSPWHKPRCLGASKYFCYLCFLFIRHHGAYFAANTHGACYDQWTIPDLADYPQPLADHYRKVVRAMDEEIQHQTHGATWRPEPMTSRENLIGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQA3</accession>
    <name>A0AAD8UQA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_719907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364565.1">
        <property type="nucleotide sequence ID" value="XM_060512224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQA3"/>
    <dbReference type="GeneID" id="85396122"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="130" mass="14355" checksum="D46E99EC99302C0F" modified="2024-05-29" version="1">MCRLVLFAGTCTRCNESLTWADLSQQLSCLEAKNADKFGSCRRGVDVETHAFDQECDACAGEDEGVAGMDFGEQDFQQYHHQYQQYQQYQHPSSAAYTAGSSSSASIPQPGSSKRGRDEGEGRKKKKART</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQK3</accession>
    <name>A0AAD8UQK3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_775204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366134.1">
        <property type="nucleotide sequence ID" value="XM_060515439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQK3"/>
    <dbReference type="GeneID" id="85399337"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="39759" checksum="9F5A2DB459C80EF0" modified="2024-05-29" version="1">MASSMMDPSRMNSSIVNPIYIDPRIMNQVLTATSNSKHIYSFGHPDASKLVEKCAETFGNILRENDHPDLTPTVKRLQKEFLAWGHEIGVLDEEGQVSEGKEVFDNVLRFNSILSKNLQMDLDSLYVHLVEVKRMTEPNPEFAFRNETWGKSTSKDPILLLGQDRTRDTTQGIGPRSRLGMTLFTLIPLRFLQIQLRLLVKLTLCEYLPQDPGVQMAGDAVKVRAAQGCCVTVPFELSGPRQTEALRDKEKNRGRKRLRKSSSPLTSATPTVNVVPGSWVEAQRIGIAAADDLKQASRLRREMVEDENMPGHRSELYQSLRNIDLNLGLGPPKSLADRGITFKDDSMIPIASFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR88</accession>
    <name>A0AAD8UR88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_574812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366449.1">
        <property type="nucleotide sequence ID" value="XM_060504745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR88"/>
    <dbReference type="GeneID" id="85388644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF30">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="45"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36570" checksum="EFE85EB62C6AE860" modified="2024-05-29" version="1">MANLIALEEHYVSPLLDAKKGGGPRPDTFGPVIVEKLGDIGPARLRDMADNSVAMTVLSHSPIHPDPETCKAINDDLHSKIIHHPAEYAAFAVLPMHEPAAAAAELRRCVQDLGFVGTLTGNHLDDGNFFDTPDFYPLWETAQKLDVPFYLHPTFPSEEESKVNFQGPYDPEIAKALGSWGWGWHSRTGLHFLRLFAAGVFDRFPNLKIILGHMGEMLPFMLDRIIGMSTRWPAPGGGERKRGLRQVWDENVWITTSGMFSLAPMACLLQETKAERVMFSVDYPFAGNGAGKEFMDKLKGSVLVSEDEWEGIAWKNAKGLLRLKFEPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URW4</accession>
    <name>A0AAD8URW4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxin 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_572644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367335.1">
        <property type="nucleotide sequence ID" value="XM_060504534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URW4"/>
    <dbReference type="GeneID" id="85388433"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26001">
        <property type="entry name" value="Pex8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="705" mass="77005" checksum="0CBF5CE591E865AC" modified="2024-05-29" version="1">MPADRLLNTVLQLYQNVHDDRKTDQIVGSTVNLLASLSNPLNLGVLTSQLLIAPAIWHRRDGLRTSLRIISIYNSAAIRVRQNELDDAKASSAANNDSRAIHTPSPTRQSGGLSSETWVRAVVKGADDRSNRWQHLLVLTGILMGMEGNDKRSLSRGLRNTLEEAVVTAANLALERQDGSFASASIVLALNYVFPFLSEFHQSAINCNALLPITVLAITGEDGFQDGGFLEDIRRDVKQNGPFVEWSPASPSFRLQQAMESKPLMGGMGPLSRLAAFAVTNATDSSAVLDAQDSLLEFAQKLFQQWQRNPLSMVDAADETARLEHNTLEGTWPVLWGTLKKTMYATVAVLQSIVGRSLLDPRMRNDVMGPQVATKTLLTLRFLFFISSRHGASAFQAYTFTYLTSLDILARLGDASVSFLAETKPPHAGVVPPGPLDRTLDLFYLNVAEHLPLNMPTEACDALIVRPATAYLTHTGALTATTVELFEAAHSAVLSVLSCPHNSALTVTLVPFYIDALFASFPAQISTRQFRVAFKTVMQIVSPPFPISLAEPQLSETLLEMVRFKALGAGTAPLPATHDALAQAEKGLEATAEQAEVLSEQSSLVLTLVDSLPFLPLSLVEEWLTLTAQAMNEIADPAVRRPVRDRFWEVLVSGEMDVERATIGVAWWTTKGGRELVVGRDQVLQQQQMPLMSGAIMDESKSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URW5</accession>
    <name>A0AAD8URW5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromatin modification-related protein EAF3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_572045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367757.1">
        <property type="nucleotide sequence ID" value="XM_060504462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URW5"/>
    <dbReference type="GeneID" id="85388361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18983">
        <property type="entry name" value="CBD_MSL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000149">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF15">
        <property type="entry name" value="MSL COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="188" mass="21667" checksum="81A4CE2FE01CB965" modified="2024-05-29" version="1">MAPARQPPQPFSKDEKVLCFHGEMLYEAKILDIQPAESGEGFQYRIHYKGWKNTWDDWVSIDRIRKFTEENKELASQLHAQMKDLRQKSSAKPPKKGNLRVNGTDSARGSEERTAGVAATGRGPRRARDFDLEQVSAKTEFLYVLLFVLRLFQFLVSFNVPLCWSSSRGSLWSELETKSERREGGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USM7</accession>
    <name>A0AAD8USM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_148547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368132.1">
        <property type="nucleotide sequence ID" value="XM_060501312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USM7"/>
    <dbReference type="GeneID" id="85385211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="25478" checksum="18D0329EA8C60883" modified="2024-05-29" version="1">MFSERRTSRDSLSNCLEPRCSQTQTRLALAIGNPHPRMPDQAAPGRLILHATKLAVLHHHGGCGGGCVLSDCVLAAARPRSHLIRVKPSPERAGALEAVRSTDGFRQGSPYGVRIPCLSRSLVYPTRPSDLGMLVPFCDDSCDVDMEVSHGVSYASGFGHTCLPQSTERKRNRHFATTRKTNLSYTLCSIHHLVVDGWQAVPMSRSPFSICKPSPPYCQMRLRGREGRFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUM8</accession>
    <name>A0AAD8UUM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_717240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368148.1">
        <property type="nucleotide sequence ID" value="XM_060511925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUM8"/>
    <dbReference type="GeneID" id="85395823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041954589" evidence="1">
        <location>
            <begin position="17"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="629" mass="69718" checksum="117470F1673FA553" modified="2024-05-29" version="1">MRAVHLLPLLCSLIEARIDRQTVVQAFNPRRNASSPETPLQVGNGNFAFGADITGIQTFSPFATMSTWGWHNFSLPTTPNQTQIEDYHGTEWWTHGRLVQYNMANPSNNDIADWLRENPHRINLGTIGFSFSDDGNTTVTEDMLGNKEQTLDMWTGVIRSSFTYKNHTVKVETWADPSSDSVAVSVESALLSSGALSVFFDFPYPTNDKFSAPFVGVFNQTDLHKTSLSTPNGGDTNKATIHHDLTTTQYDLSLEWDVATGGSGAIKTPTDGSHRYVLSPSGTDTLRFTANFAPSAPASVAEFDGVVAASREWWPSYWNNGAFVDLTGTPDANATELQRRIIQSQYLVAVNSASDYPPQESGLVNNGWFGKFHMEMILWHTLQFARWNNHALLARSLPRTYTHLLPSSLARARTQGYAGARWGKMTDPSAIDAPGEINTLLIWQQPHPMYFAELAYRHAPTPQTLADWDDVLTATADFMASYAFLNETTGIYDLGPPMYPVSENTNPNATVNPTFELAYWRFGFDETAARIWALWDLDESFGWDFPMLAMNSLRLGDANRAVDYLLHPTFQFDDAGYPVGGTRVPTPYFPSSSSLLLAVAMMAGGWDGEEGSHFSSEWDVVVEGFVPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVM1</accession>
    <name>A0AAD8UVM1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heat shock protein 30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_571064</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368181.1">
        <property type="nucleotide sequence ID" value="XM_060504373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVM1"/>
    <dbReference type="GeneID" id="85388272"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15239">
        <property type="entry name" value="7tm_YRO2_fungal-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043476">
        <property type="entry name" value="Yro2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28286:SF1">
        <property type="entry name" value="30 KDA HEAT SHOCK PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31675" checksum="DFFA02A0A6A772BD" modified="2024-05-29" version="1">MGLILQRSNEALDINSTPGIEEQLSVNGSNWLWTCVAIYSVFFLGVFALSWKPRGNEKVFHYLLSIALLVGAITYFSNASNLGWSIITQGTTSRSGAPRQIFFNKYINWVVAFPIVNILLGLVANSSWATIVWHVFFSWVWVISYLVSAYTPSVYKWGFFVFGTVAYLVMAASTFAEGSIGAKRVGTQGDYWILAGYFNLLWLLYPIAFGVSEGGNTIGVTPHFIFFGVLDVLMIPCGAVVFLLLSRKWDYNALNLYFTQYGRVPQGGHFPEKSAAPAPAPAATPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVP3</accession>
    <name>A0AAD8UVP3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="12">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_572938</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367205.1">
        <property type="nucleotide sequence ID" value="XM_060504569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVP3"/>
    <dbReference type="GeneID" id="85388468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000020">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 9 12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="13">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="13"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="10">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1727150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="338" mass="36240" checksum="98173535AA076DE4" modified="2024-05-29" version="1">MAPIKVGINGFGRIGRIVFRNAVEHPEVEIVAVNDPFIETKYAAYMLKYDSTHGIFNGDIQQDGNDLVINGKKVKFYTERDPAAIPWKDTGADYVVESTGVFTTIDKAKAHLQGGAKKVVISAPSADAPMYVMGVNEKTYDGSADVISNASCTTNCLAPLAKVINDKFTIIEGLMTTVHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPELNGKLTGMSMRVPTANVSVVDLTARIEKGASYDQIKAAIKEAAEGPLKGVLAYTEDDVVSTDMIGNPNSSIFDAKAGISLNDNFVKLVSWYDNEWGYSRRVLDLLAHVAKVDASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVY1</accession>
    <name>A0AAD8UVY1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Survival Motor Neuron Gemin2-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_750275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367325.1">
        <property type="nucleotide sequence ID" value="XM_060513902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVY1"/>
    <dbReference type="GeneID" id="85397800"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040424">
        <property type="entry name" value="Smn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267:SF1">
        <property type="entry name" value="SURVIVAL MOTOR NEURON PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39267">
        <property type="entry name" value="SURVIVAL MOTOR NEURON-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20635">
        <property type="entry name" value="SMN_YG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="17477" checksum="225CB41F8F3684B9" modified="2024-05-29" version="1">MAGNDVEMSHSEMWDDSALIESWNEALDEYKKYHSIHAKGGKLKDLDLQEKTDEAQTADDAQTQAVDQPEIADDAAEGADKTKGLSSTDVQDQADSTSVSMAKANAPPGPATMGPQSLLGSVQDEGLKRLLMSWYYAGYYTGLYEGQQQQQQQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXY7</accession>
    <name>A0AAD8UXY7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acetohydroxy-acid reductoisomerase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_648394</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368780.1">
        <property type="nucleotide sequence ID" value="XM_060510177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXY7"/>
    <dbReference type="GeneID" id="85394076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000005">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000013">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000167">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016207">
        <property type="entry name" value="KetolA_reductoisomerase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000119">
        <property type="entry name" value="Ilv5_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="13">
        <location>
            <begin position="65"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="14">
        <location>
            <begin position="287"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1728725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="42498" checksum="9A9424F558A7990F" modified="2024-05-29" version="1">MASRSFSKALRSPMARQLAAKPATQQRTFVAARQLVRASAQVNKAFVAPAQQQARGVKTMDFAGHKEDVYERADWPQEKLLEYFKDDTLALIGYGSQGHGQGLNLRDNGLNVIVGVRKNGQSWKDAQQDGWVPGKNLFDVDEAISRGTIVMNLLSDAAQSETWPAIKPQLVKGKTLYFSHGFSPVFKDVTHVDVPKDIDVILVAPKGSGRTVRSLFREGRGINSSFAVFQDVTGKAKEKAQALGVAIGSGYLYETTFEKEVYSDLYGERGCLMGGIHDRRGGHPVPVPLIGANGMDWMYEACSTTARRGAIDWSPKFKDALKPVFNSLYDAVKDGSETKRSLEYNSQKDYRQKFEAEMEEIRNLEIWRAGRAVRSLRPENQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7C4</accession>
    <name>A0AAD8X7C4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tf2-1-like SH3-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000315">
        <property type="protein sequence ID" value="KAK1702255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357115.1">
        <property type="nucleotide sequence ID" value="XM_060506819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7C4"/>
    <dbReference type="GeneID" id="85390718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tf2-1-like SH3-like" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="13537" checksum="7DEBD15D62AFC6EC" modified="2024-05-29" version="1" fragment="single">RNANRFRIKRLTLKKGDSAYFLYYNIRIKRLNNKLNYKKLRPFKIIKRILPVNYKLKLLNIIKYYLVFYILLSKLIFKSLYIENCIIIKLNELEYKVERIIDYRIKNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAN6</accession>
    <name>A0AAD8XAN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_590241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359336.1">
        <property type="nucleotide sequence ID" value="XM_060506317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAN6"/>
    <dbReference type="GeneID" id="85390216"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="103" mass="11766" checksum="2AACDCBB6D41CE5F" modified="2024-05-29" version="1" fragment="single">CSGITPTCSRCSPQDVDCKWVTESAMMYRRAIAKCLEELEKLEKVNSDLHELVRELSSRPEAEAVEIFHRLRTSGDAFHVLHLVRTGDLLRRKQPNEAGERSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAS1</accession>
    <name>A0AAD8XAS1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_586794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360834.1">
        <property type="nucleotide sequence ID" value="XM_060505978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAS1"/>
    <dbReference type="GeneID" id="85389877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="223" mass="24976" checksum="77139CCBEE9FC9EC" modified="2024-05-29" version="1">MYVTCAQNHFVRDEIQSYIHNATSLISVKKPPLETEFTFKSSIPDLDETLLIITSLPCIAMYHCDITWITPDQTSENQQKLEHGPQLLHQQRQSREQEAVSADTRTHSHQPAQHQQHHKQHNHQLSFVDLLVSDSRGQELKGTRLPFVRDFLASHHRDGNHIASEHTSGQLRSISLPGVLTPNQQSLLSPLPTASSVSQSSQVGTSSATPTRPCVLSSRRPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAU3</accession>
    <name>A0AAD8XAU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mediator complex subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED9</name>
        <name evidence="11" type="ORF">BDZ83DRAFT_722540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAU3"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011425">
        <property type="entry name" value="Med9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07544">
        <property type="entry name" value="Med9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="34"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1717422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="16589" checksum="6AA99CB260FA18F0" modified="2024-05-29" version="1">MPPHPLELPPTLSPDALDTLTELTGILTRLRTAIQTSGSSSSSIGGGLTTGATPAGAGATPNPLGGGAASAGSPNAPLSLKDVPAQTDALKHKLQRARTQMRTLPDMERTVEEQEEEIKELEERIRMQREVLDRLREAGVKFGHEEGGRGDKMETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBM5</accession>
    <name>A0AAD8XBM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Initiator tRNA phosphoribosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361312.1">
        <property type="nucleotide sequence ID" value="XM_060512457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBM5"/>
    <dbReference type="GeneID" id="85396355"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007747">
        <property type="entry name" value="Ribosyl_Ptfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="2">
        <location>
            <begin position="50"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="1">
        <location>
            <begin position="384"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="511" mass="55886" checksum="6BB6560658B142B7" modified="2024-05-29" version="1">MNESPRIHTVPSATAIAPDQSASTVQTPALSDLIFPTTANHNFSHILTDLKRSNLSIANRLRSITQDADFVQDAAAGFDRPLVANERCGSWYIRPADKRASAYFKSTDGHTNAWKFSTRRLNLHLLELVGKHDGCIIVDSTRRGKRMPDALSKTIPVWCAVLNAALFPDLDPARELRLFTPPNVVSASEHAQIAALLPSFLASLKSLDLDLAALRSHVSKPLRPFWVTQETQLPSTSAGDDDESLKNVVFEDYHPIICCTSSRRVAGTEMSEAGYIQGAGDDTENWALGLTAEVFWENATALLSCPEADLPELVVRLVAEGKRNAPMGLQPKKVAPRIYVCPLPLDDERDSSSGGTDAVSAGACRVVLTQDVTPRESWVKSPTYMQVGLGKHKIASRNLRQALPDICAFVSRYLDSHRDIVEGAAEGDSSSRGSVLVACETGKDLSIGAALAIYCWCFDRDGKFRVADSTTFFNKDMIRVKLGTIMTAFPEANANRATLQSVNSFLMDHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCH4</accession>
    <name>A0AAD8XCH4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_629767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362242.1">
        <property type="nucleotide sequence ID" value="XM_060508780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCH4"/>
    <dbReference type="GeneID" id="85392679"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF38">
        <property type="entry name" value="PROLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="2"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="42394" checksum="A03566D3571BC470" modified="2024-05-29" version="1">MLVMVVGLNLLPVKFYGETEFWFAGLKVLTIVGLLILSIVLFFGGGPSHERLYFRYWKDPGATKELIVQGDAGRFVAALSTLLSSVLPFTFSPEMVVVTAGEVQSPRRNLPKIARNFFWRLIVFYIGGTIAISVICPSNAPALTSGSSGAAASPWVVGIKNAGIKGLDSVINAVVVTAAWSAGNSFLYLASRSLYSMACEGSAPRIFKRCTKQGVPIYAVIASSLFSLLAYMNVNSNAADVFNWLLNLVNTGGFISWVCCGIIYIRFRKACDVQNLPKSALVARSFLQPVGSYISLVIFGLLCLLNGFTVFFPSRWSVADFLSAYIGLPLFIVIYFVHRFLHRADSWAISSHEVDLKTGLAELEAEESLEEPKEGLRARFKRHVGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCU8</accession>
    <name>A0AAD8XCU8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Efflux pump</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_743294</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361616.1">
        <property type="nucleotide sequence ID" value="XM_060513138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCU8"/>
    <dbReference type="GeneID" id="85397036"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1719532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="41059" checksum="550FEAB02741AA94" modified="2024-05-29" version="1">MSGGLTIIAGSVPLEKRPALMGLVIGLANSGSVCGPVLGGVLTDYANWRWTFYINLPIGGVVLLFLAWCEIPDQVPKASPMAVIAKLHTYLDFTGFLLCAGAAVSFLTALELGGNEYAFNSPTIIGLFCGSAVALVTFLAWNYRKGDDGLIPSSMAGKRPVWSAAVTNFTFVGSAMIQIYLLPLYFQAVQGATPVQSGISVLPSILSQLAFAYGGGVLVGKFGYYLPWAVAGTAATIVASGLFTSLTPTTSVAQWVGYQIITGGGRGIVLQLPSIAIQANLPPEQISLGISFVTFSQFMGSAVALAVGTAIFTGALKQDLPKLAPNVDASMILEAGATGFRKVTPEKELPGVLLAYVSSIDKEFYLSLGLAIASFCFAWGMGWKDIRPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDD1</accession>
    <name>A0AAD8XDD1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360593.1">
        <property type="nucleotide sequence ID" value="XM_060512503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDD1"/>
    <dbReference type="GeneID" id="85396401"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43812">
        <property type="entry name" value="BLR2425 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43812:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="237" mass="26309" checksum="C648AA295E4F972E" modified="2024-05-29" version="1">MFYQPGVDDHGLPYDPFKACVVPRAIGWISSVSPNGEHNLAPYSQFTNVSFDPPMVMFSANQTYAEGRKDTVNNIERTGSFCWQLATYPLRESVNISAEAIDPNEDEFLRAGLKKTWSKSLKTSVPMVADSPVRFECEYMQTVRLPGKPPMGTVDVIFGKVVGVHIDDSVLTDGRIDVSKTNPIARLGYFEYGIINDRFEMIVPGDKRMLIGLEGNASNNTKDNLKEGSDASTRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDJ5</accession>
    <name>A0AAD8XDJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin interaction domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_430791</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362381.1">
        <property type="nucleotide sequence ID" value="XM_060503046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDJ5"/>
    <dbReference type="GeneID" id="85386945"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF4">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="5">
        <location>
            <begin position="401"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="467"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="3">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="62300" checksum="3C7F158DD6F455FF" modified="2024-05-29" version="1">MEEERIARLKKRSATEAGIDTQYSQRSKLQRPEASESHKVFGTAKSKAATPAISATPVADALELPFPKGAFKRTWAYGCPRNGEDIKIEEVLQRDKLQLAVLSSFQWDEEWLLSKVNARNTKMLLVAYANNDAEKANIRSNIPAGSLIKFCFPPMHGGYMHSKLQILKYEGYLRIVIPSGNLVPYDWGETGQLENMVFLIDLPRLNGPLIKTSFGTELRRFLKALGLDEKLVKSLDNYDFSETSRYGFIHSISGSHTKEAWQHIGYCGLGSSVRSLGLATENAVDIDYVASSLGSLNHGFLTTIYYACQGDSGMKEYEARQSKTTKSKAAKTGLGGSRPVDIDKEPLQLQHHFRIYFPTEKTVSSSRGGRSSAGTICMQEKWWNSSTFPRELMRDCQSARGGLLLHSKAIFVRERAHDGAVWAYVGSANLSESAWGRLVKDRESGTAKLTCRNWECGVLVAVKDSSAGTGDQDAQAQSRPRAKAQTGTLEGHAESEETLGGKEGMTAAAAESMGKRRHQQLDQDGSVGLDGVFGATMPIPMRVPARRYTSDESAASRPWFFVKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEA8</accession>
    <name>A0AAD8XEA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_578265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364659.1">
        <property type="nucleotide sequence ID" value="XM_060505105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEA8"/>
    <dbReference type="GeneID" id="85389004"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="570"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="739"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="816"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="739"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="775"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="839" mass="91602" checksum="BECAFBC305D10CE0" modified="2024-05-29" version="1">MSSTSTKIGHGLAKVLGIKLEKPENEEMLRGESVFSVQSSDTFVEEEPTTAEWLLELLPDGHEVLAYIRSLFPFLNWIGHYNLQWFLGDLVAGVTVGAVVVPQGMAYALLAKLDPQFGLYSSFMGVIIYWFFATSKDITIGPVAVMSTVVGNLITDVQADFPQYEGHQIASALAIIAGAIILFIGLIRMGWIVDLISLTSLSAFMTGSAISIAVGQLVTLLGIKGVNTREATYMVFINTLKALPKTKMDAAMGLTALTMLYLLRFIFTSLAKKYPQKSKLFFFLSTLRTVFVILLYTMISWLVNMNRRSNPLFKILGEVPRGFQNAGAPKIDTDLISAFLPFLPASVIVLVIEHVAISKSFGRVNNYTINPSQEFVAIGVTNVIAPFLGGYPSTGSFSRTAIKSKAGVRTPFAGVITGLIVLLAIYALTAVFFYISSASLAAVIIHAVGDLITPPNTVYQFWRVSPLEVVIFFIGVFVTIFSSIENGIYATICISAVLLLWRILRSQGRFLGKVKIHSVVGDHVIGEDHRQVIGEYGTFNASDNAARNVFLPIDHGDGSNPEVSLDEPYPGIFIYRFSEGFNYPNASHSLEYLTDYIFSRTRRTNMQSYGRLGDRPWNDPGPSRKAKKAQAQMHEEENRATLKAIILDFSSVNHVDLTSIQQLIDVRNQLDRYASPDKVNWHIACINNRWTKRALVAAGFGYPVDRSDGTQHQWKSIFSVAEIGGSESAAAVAEKEANEKELSTHARAARTIDEEALGKDGGAYDQIDPVSSGSRKGGAAGGNIGGGPRRKGVVVHGLNRPLFHVDLTSALQSAIANSEGRGIVEDEAEDPKSPSTSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEB7</accession>
    <name>A0AAD8XEB7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase</fullName>
            <ecNumber evidence="9">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_584929</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361658.1">
        <property type="nucleotide sequence ID" value="XM_060505806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEB7"/>
    <dbReference type="GeneID" id="85389705"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000002">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="496" mass="56291" checksum="750E31A055334A80" modified="2024-05-29" version="1">MADSTVPEDVAQVTDGDVAMEEAEAPAPAAEEKSEVKLDDLFADADSDDEFPSSRPRDAPSSSPDGVLTPPSPTDIADLKASDPEVMRSFYQRLFPWRYLFQWLNHSPSPTNDFGHREFAFTLQNDAYLRYQSFASHDLLRKDVLRLMPSRFEIGPVYTTNPRDRKTLRNASAFKPLAKELCFDIDLTDYDDVRTCCDKANICNKCWQFITMAIKVVDVALRDDFGFKHIMWVYSGRRGAHAWVCDKKARTMGDQMRRSIAGYLEVLKGGAQSGKKVNLWRPLHPHVSRSLETLKSHFQEDVLEAQDPWASNERAERLLQLLPDRDLNESLRKKWDAAPGRSSIAKWADIDTVAKSGASKKLDAKALLEAKQDIVLEYTYPRLDIEVSKKLNHLLKSPFVVHPGTGRVCVPIDTKKLEDFDPLAVPTVQSLLAEIDAWKGGDEDAEGGSQQKSVQDWEKTSLKPYVEQFRSFVIGLMKDERDVKVKREREEDSMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEC6</accession>
    <name>A0AAD8XEC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gentisate 1,2-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_679910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360550.1">
        <property type="nucleotide sequence ID" value="XM_060511194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEC6"/>
    <dbReference type="GeneID" id="85395093"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02216">
        <property type="entry name" value="cupin_GDO-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047183">
        <property type="entry name" value="GDO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41517">
        <property type="entry name" value="1,2-DIOXYGENASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41517:SF1">
        <property type="entry name" value="CUPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="3">
        <location>
            <begin position="96"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="36364" checksum="CA642210C5EF1235" modified="2024-05-29" version="1">MDSPHEDDNRAKAMNDYLEELPSQHMEPLWSKMNVMVPPTPAPVAKPHMWKYADSLPLLHKAAEMVGEKQAERRVLMLVNPNMESPYTTDTIYGGLQIVNPGETAPAHRHIAFALRFIIDGEGFTAVEGKKMPLRRGDVVVTPTWHWHDHGNESDAPVIWLDALNLPLFRFTPVHFAEQYHESRYPSVFTETCVWRHPWDQVEAELKAQEGPYAIHHYTSHGKPLSPILGAQAERIDGNHTTQEVREQASFLYHCYEGQGRTIVEPPTGPRVVFKWTSRDTFAVPAWSKIQHINEGSTTAYLVAVSDRPLLSSIGLIKPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFJ9</accession>
    <name>A0AAD8XFJ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arabinosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361720.1">
        <property type="nucleotide sequence ID" value="XM_060505799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFJ9"/>
    <dbReference type="GeneID" id="85389698"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF8">
        <property type="entry name" value="ARABINOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041974132" evidence="1">
        <location>
            <begin position="22"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="37457" checksum="B6FFCCDC68739C86" modified="2024-05-29" version="1">MPSLKSLLLLGASLAATSVQASPIQSLDFSGTSLAPRADPSLTGYLGAFFLGADPYVYLYLSNGNNPTSFRALNSGSPVIRPTKGTGGVRDPAIVVGGGAEKGKKWYIVGTDLNIAKTTWDAAQRQGSKGIFVWESTDLVNWTNERLVVVENSSAGMVWAPEAIWDAAKGQYLVHWASKFYPASDPNHTGSPGAIVIRYAYTSDFKTFSTPQTYIDKSPTNIIDLNILPTGTDGKSFVRFLKDESLKTVFVEVSTTGLFGTWTRPGGSSAVIASGVEGPASYWDNQVAGKAHVLLDFYGDDGYRPYETTNVASNSGWTASSRTGFPTGLRHGGVLPVNQTIYDALGKRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFR1</accession>
    <name>A0AAD8XFR1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lysr family regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_581638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363143.1">
        <property type="nucleotide sequence ID" value="XM_060505478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFR1"/>
    <dbReference type="GeneID" id="85389377"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF69">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="61007" checksum="7CDC866C8FFF4E3D" modified="2024-05-29" version="1">MDYMRSFVGRKPKRTQLPTVATDDVYPVHFFDDTKPFREMLLNWTLRFDDVLDAEKLNLSLSRLIEIGDWRKLGGRMRMRPDNQLELHVPKQFTPARPAIRFSHDVHDFSIKEHNVAKHLPTTTSTPSVQPGVINFYNLGARQDAPKTLEDLMCSDEPQIALHVVSFNDATLVGLLFSHVMFGAAGMQALVQAWSQVLAGREAEVPDIHGAHKDILDDVGVDTDPEKEAYLLDRKQLKGFRHFRFSLRFLWDMYRRPEIESKVLCLPADFVAGLRARAMADLHAMDEKGLGTEEAPFVSEGDVLTAWWTRLVCLARGSNRPVTVLNAVDITGRLKSVFAPGKLYVQNFALGTWTLLSSAEVLKAPLGYVARCFRHDIQTQTTPSQIMAFMRCLRAGGRCSSQPIYGDPNSMLIIFTNWARCKFFDCIDFSPAVIPRISEPITVNGDIQTNGNTTGSDPEKNAANATITEVLNRPPPGKIAYHHSLARTRSILSRNVFTILGKDLQGNYWISALGHPECWDKLEKEVSMSSMDALRNLNPPSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG86</accession>
    <name>A0AAD8XG86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_386143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363713.1">
        <property type="nucleotide sequence ID" value="XM_060502744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG86"/>
    <dbReference type="GeneID" id="85386643"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="243" mass="26665" checksum="499A71B428531118" modified="2024-05-29" version="1">MQCDGALASLPILGSFLRQSLIACPPVHPSTTLRDLLAPPPSSWDLQTIFDYSLFWHLAATQTSTPPANANQRHSRSMQDISIPADSSPLFSNGFLLIGYRTLAGGGHPSGPLPRPYQTSPLIVTRCPSRPSPEILGFGAFDSPKTNTSDINLRHSFGASFPMSSLTVIQGELGQDLLASPRLPNNPAGSGWSLRVPMCHGSCQFQAQTSRHYTTMLIYSYMGAMWMERRVRRVRGAREHHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG93</accession>
    <name>A0AAD8XG93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_718221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366879.1">
        <property type="nucleotide sequence ID" value="XM_060512044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG93"/>
    <dbReference type="GeneID" id="85395942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044843">
        <property type="term" value="P:cell cycle G1/S phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20559">
        <property type="entry name" value="CYCLIN_ScCLN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="95"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="190"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="193"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="406" mass="45783" checksum="3AF4365C7B4AA605" modified="2024-05-29" version="1">MAYYQQQQQHSDPTFFTEDHDEPQRPRMGTRDAAKMIARQRQEIIASELSRIAGDEYLEDIMKHMRHMEDETMPDANLIDMQREIQWYMRPYLIDFLIEAHAAFALLPETLFLTINLLDRYCSKRVVYKQHYQLVGCAALLIAAKYGDKKDRVPQIHELNNMCCGLYDAGMFTQMEMHVLNTLEWTIGHPTVDFFTQLIVAEEHDKVEVEHMAAYICEIALYHRDFVSTKPSIMARSSLALARAILGEPEINDGEWDHVENVTLLTLSQHLHSPSVALARKYSSSHFSGVAKKLASFMAHQASIARAQSGVPPSPPSESASKHSNIYSTPHKGHGAVAGLVEGYMTPPITPDGAAYGTVNKDAYSMPPRCPVTPTPQPNTAAYAQQQVQQQYAPFVHHHTTGHHMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGB6</accession>
    <name>A0AAD8XGB6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_383914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363803.1">
        <property type="nucleotide sequence ID" value="XM_060502729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGB6"/>
    <dbReference type="GeneID" id="85386628"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="69200" checksum="95479AD953D55F8E" modified="2024-05-29" version="1">MWEVVWTDPDRESRKEHRERKAVEREHKDKTRASRSSMSTRSSSSSDNKPFSFFGSRSLKRTLTPSSTKTSTTHALKAPSIDSTFRGSLLSAVSEPPPLPTELPCSPVTTVERTYMPQEQHSVESQQNSPISSNRDSVFSKWTDTSVGGPISPCNTSVAESTSAKREHYVQTLGPTSFITKSTEVTILPRTIENDISGMISHITITAEPVKEEPPTPPRSPTAQPAVTAMISPAMLDSPVNLFPGHPSPQRSLRRVPSWSMAFKPNNPDSWRPPDAWDCGPPPEVRTPVIEAVIEETPELDAACAMSMDLNGMQREIRRMAAASHSIRLLRLKEVWGETTDASLYKELEMEKKRWVLSSLHNMDKPVEGDQAKAHPNKITPAKAKKVLALYETQATTSYLAAVHFNKQVYHLASLPLSHTLFPNIHPVNVPAISPSAFPVAPSLFGIVYSLALPALLPSPEVPSLLKNVHRCLAAGGAFHLTLIDPLPVTSTLGPLMRSWIEENLIFNLEKNFRCMNPSKLFPLWLADASLRAEGSTITTVRFSAIPPTDRPDTATTDAEVLADKAVKQELRSIVGRMLWREVWGQYITADQWWWENPRIVEECEQLKTAWEYSIIEAVKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGQ9</accession>
    <name>A0AAD8XGQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_700829</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364268.1">
        <property type="nucleotide sequence ID" value="XM_060511436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGQ9"/>
    <dbReference type="GeneID" id="85395334"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="59293" checksum="BAF902BFBB0B1CF1" modified="2024-05-29" version="1">MELPALAGTVFAVVVIGCYLLESFFYLSKNPQEPEYIRPRVPLIGHLLGLNKYGSGNYFTKVGADAKSKIFSAPIFSFKFYIIAERKFISSIQRNARTISFAPFAAKAAHNFSGADEKATNLQDHLGGGPEAKEFDRVQRTTLAAGPELDDMSLVATQVKLEIVDRLAASALESSETGVPIDLFAWVKHTVGLSATEGMFGPLNPFKNPDHEADFWIFADKAHLLLPGGIIAELFAKKAMQARERNGLRYEEYVRLGGTETASGLLKGRSRIMAENGVSPRDIGRINIGFDIAMLANYVPTTWWSVFEVFSRPWLVDAIREEVRKAVKKDENGEICLDISIIKSACPLLLSSIQEAQRLHTIHAHIREVLRDTTITVDDKTQLLKSGNYVQINGIPILRNEETWGADATSFDAYRFIKMKKKPDTPGVAAPGDLAPHSFPIWGVAPHVCPARWFATTGTMTLIALMTLKLDLEVAPDFKGEGPSGREWRMPKVEGLFVALHSPAEPIPITVRSRKEFEGKWKVETGAPGTRLQLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGV8</accession>
    <name>A0AAD8XGV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NST UDP-N-acetylglucosamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_285057</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365876.1">
        <property type="nucleotide sequence ID" value="XM_060502158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGV8"/>
    <dbReference type="GeneID" id="85386057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005462">
        <property type="term" value="F:UDP-N-acetylglucosamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005464">
        <property type="term" value="F:UDP-xylose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF4">
        <property type="entry name" value="NUCLEOTIDE SUGAR TRANSPORTER SLC35B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="411" mass="44551" checksum="F2964891C7E24D57" modified="2024-05-29" version="1">MSSPATTRRRGQPKGLSSPPMEKMDSPARGYDDEKTADQAANGMAMNRHASSEKSLQTAGRIVAGLFSQWITVGVMLGLIFGGCCSNVYALEAIIKVEPASGTLLTFVQFLFVAVTGYFSQFDRSRPPFFLQQNKVPIRRWIINIVLFFSINVLNNHAFSYDISVPVHIILRSGGSITTMVAGSLYGKKYSRIQIVAVVLLTFGVITAAWSDSQSKTSSKATEGSDKPAFGTGLVVLFVAQVLSAIMGLYTEETYKQYGPHWRENLFYSHLLSLPLFLPFAPSLIRQFRKLANSPPLSLPMAQLPGLGLNGDVGDGLSKLQIPSQLAYLVTNVVTQYACIRGVNLLAAVSSALTVTIVLNIRKLVSLLLSIWLFGNRLAVGTLVGAIIVFGAGGLYSLDSRAKTSRVQKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIU7</accession>
    <name>A0AAD8XIU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366743.1">
        <property type="nucleotide sequence ID" value="XM_060510350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIU7"/>
    <dbReference type="GeneID" id="85394249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="24265" checksum="BC1857A918995FDA" modified="2024-05-29" version="1">MSNPTLSKQQRIQVWREEVAASASLCTCPPSSPAASASSTNISLSAASSSASSSASSPGAGDAFTFPRSDILPGQGTYCPTCSRLGAPSAMGLEPSSAYLDQTQPGGVLPGSHIAPGIFRAKTANNALFRGMRNFVRKLSGSRTSGPMPPRGAEDATKMYRRATLAGWPTATNTALAAEAAAAMAAGDEPEAEDADCAVDEADSEGRGHVPKLIAEKQARLRRAERLLARTNAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKC5</accession>
    <name>A0AAD8XKC5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prp 4 CRoW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_89126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369015.1">
        <property type="nucleotide sequence ID" value="XM_060515980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKC5"/>
    <dbReference type="GeneID" id="85399878"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042020395" description="Prp 4 CRoW domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="27709" checksum="0AF758D6ACA22577" modified="2024-05-29" version="1">MHIRSLASVAFVAFAAQAFAQQQTKIFKRSITAGRDLGLMRRADDGYQPADEVCNKGGNTCAEACGTGYEQCKSTDQAVHCFNPAAGETCCSTTTGNSCLSSFYCTHGSNSDTTCCPNGMNLADCAAKHGVSGLTSDPPVVASTSVPPTTSKTTPPPTTSSTPAPPTTTSSSVVVTTSSTPAPSSTLIPSTSAVPSTTEVTTEVPTTFVPSAGTSTAFASSNGTTLATTSTRSSTRSTVFPSAATTSASAPDQNAGSSNGPAGMAVLLGAAFVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKF2</accession>
    <name>A0AAD8XKF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_763978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369058.1">
        <property type="nucleotide sequence ID" value="XM_060515226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKF2"/>
    <dbReference type="GeneID" id="85399124"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="243" mass="25847" checksum="AD9842C5282BD037" modified="2024-05-29" version="1">MYSVVLATLVHSSRGQTFKAKYWAEQGVSHVQMGSRFLVHSVLVSVPWSLGQELQIQTGRAMDMGAVPGPGVSMSTMSMAPCSFVFPISSILNKADTPSLSLKAHPTPCCLLFPDLCLRACAAFANLEKRDIPYQYLFTDTSYSCVQSTFGSNPSLAPVPAKPCWASHASPFPIAPLPPSHRFVLCTDTVRSISLAPVILLLSTIVPIPVPVTAKLLASRACQPPTSDPVGLPDGPVPVACLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKG3</accession>
    <name>A0AAD8XKG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial division protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_607750</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat MDV1/CAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369073.1">
        <property type="nucleotide sequence ID" value="XM_060507448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKG3"/>
    <dbReference type="GeneID" id="85391347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22881">
        <property type="entry name" value="Mdv1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000404">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000881">
        <property type="entry name" value="Mitochondrial division protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="357"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="434"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="540"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="658" mass="73127" checksum="1C9E73484AB1865F" modified="2024-05-29" version="1">MAASDHDQYGFHDDAAAGDDQSVLSTRGIEAFGRKVTTTASHLMGPLSEQGNNNHHHYHGALAEVHKQLRRPTIQRSMFSMAKTTPTDMVRSKLSTTEIQHRALTYLPDELLANIPESDNSYSLFQGFKASFPDLTEEGRKHRRRVSRGRKLLEDTENTAGTPQALHNLKKDKASMMHELEMLGVRKNMASSEIRDIDNKIANLHGMRRIILDRLANLEQEETLLEHDLMDVETRLEDAQELVDEAESIAINTPTKTEEDLAGEDDSGFMSQSVYEKLPTTAGTPASKAKKRVVRRKSMPILHEHFEAGTAIREIRAHQDTITALDFDAPFGTMVTSAMDDSIRVWDLNAGRCIGLLDGHTASVRTLQVDDNFLATGGMDATIRLWDLSKAHYDPHGSQYGRDEDEDGIAFENPDDGPVEPPEGSMRDCHLYTLQSHVDEITALHFRNDTLVSGSADKTLRQWDLEKGRCVQTLDVMWAAAQASASLGSESSWRQTNRAPAQQADFIGALQVFETALACGTADGMVRLWDLRSGQVHRSLVGHTGPVTCLQFDDVHLVTGSMDRSIRIWDLRTGSIYDAYAYDNAITSMMFDERRIVSAAGEDVVKVYDKVEGRQWDCGAGISDAEEGKTPAVVERVRVKDGYLVEGRQDGIVGVWTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKS7</accession>
    <name>A0AAD8XKS7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_607067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369251.1">
        <property type="nucleotide sequence ID" value="XM_060507409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKS7"/>
    <dbReference type="GeneID" id="85391308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="70" mass="7597" checksum="15AB40487BCD4634" modified="2024-05-29" version="1">MGGVWALIGAWQLVRLQRREPPWNDLSLRSPSVIFLDPPRASLFVLMSQGSMVFVSSNRGGLLGGPTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKW7</accession>
    <name>A0AAD8XKW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_607063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369249.1">
        <property type="nucleotide sequence ID" value="XM_060507408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKW7"/>
    <dbReference type="GeneID" id="85391307"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="554" mass="61130" checksum="D41B2417A71DA186" modified="2024-05-29" version="1">MQWADLRGLRSSTLRVARMTTIAARRRLPLLQQLPLPQTPASTLRRFFRADHDSGTRLFSTQPQRSSPDDKWGKKKPSRKEEPKANPPSLFEELFPNDDIYSHSSRRNNEQDDGEGKGKVKVRFLTSTDPEKSEATEYRLRQLERKNKSSKAGGEAAGKIADFFESSAREKEKRDKAADGESSSIFNELFSSPGSGGAESAAGAVLGKGGVEALLRNSQAGQNLSEERSVDHNDLQSWIDSLPKDDAANTDSSESASPEEKEEAAAAKAERSAMLILSNASPNLMETDFYRIGPQGQHLDGWSASITKVMQAYDYGTLAPMDRYFILFDSHAAAAAYQREAQRLHALAGRALTSPAAGLASAETSSTSSQTSVFSLAPPSKTPLNLHLYKLNRATEARLETFSIQGLLSMTPEPPPRANAHVVLSLDGGTLDQRSLSHWIRRDARDRNLGWPVQHLRPYFAPKVHQRTATKAQQPTETEEGLVYDEDDAAPAVTEADSGRRSTPNALDETAPSGRFVVSFPDVHEARRFVRAWHKKELILTNDQSVIVNTHVVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKY9</accession>
    <name>A0AAD8XKY9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_748406</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369355.1">
        <property type="nucleotide sequence ID" value="XM_060513612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKY9"/>
    <dbReference type="GeneID" id="85397510"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="393"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="863" mass="93177" checksum="E851A4E774828CD9" modified="2024-05-29" version="1">MDVEALLEQLTLEEKISLTAGVGWWHTATVERLGIRPIRLSDGPNGVRGTHFFDSTPSACLPCGTAIGATFDVELVQRLGRLLSDEAHAKGAHVLLGPTINTQRGPLGGRGFESYSEDPVLSGILAGNYVNGVQESGVSATLKHFVCNDLESERMAVNAIVTDRAMREIYLLPFMIAIEMGKPRAIMTAYNQVNGVHAAESKKILQDILRDEWKWDGLVMSDWFGTYSTSEAIKAGLDLEMPGPSRWRAGALSHAIMSNKVKRSELDSAVRNVLKLVKQGLENTSIPPNAPETEANTPEHIALLREAAAKSLVLLKNERNILPFDKKKKIAVIGPNANIATYCGGGSAGLRAYNTVTPLEGVKSLASEVVFSQGAYGHQSLPLLGKALKTPNGKQRGFVLRIYNDPPPKDTASSADSRTPLEERVLDDANIWFVDYENADLNPIWWAETEGTLVPERSGEWDFGLSVHGTGELFIDGKLVVSNVENQRLGSSFLGCGTVEETGTMHLEAGRSYRVLVRFGCSATSKVKASGTVDFGQGGVRFSGCPKLEPATAIQEAVEVAKSVDQVVVCTGLSGEWESEGFDRTTMALPPGTDELVAAVLAANPNTAVVVQSGTPVSMPWIDQAGAVLHAWFGGNESGNGIADVLFGEVNPAGKLPLTMPRRVQDNPAALSFRSDNGRCLYSEDVYVGYRWYDTLDIEPLFPFGHGLSYTTFEVSDLEVSDTSAQTNGHANGNNTITIQEADNLTVRVKVGNTGSRAGSEVVQVYVTPAARTPLTSTTRDTITRPKKEMKGFAKVTLEAGASATAEICLDVLRATSYWSEMEDCWRSDAGSYGILVGTSSRGEFLEKTVKVEKSRTWRGLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB1</accession>
    <name>A0AAD8XLB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_788865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369567.1">
        <property type="nucleotide sequence ID" value="XM_060515687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB1"/>
    <dbReference type="GeneID" id="85399585"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9535" checksum="59A6BC95A48B939E" modified="2024-05-29" version="1" fragment="single">NIAFVRRCARLITACKAKRLYQAILLLVICNPDPPCRAAKHDCLLVLPAFRRQFIRWSQPRKGKTDQDSARHGRSNGCWNVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLF4</accession>
    <name>A0AAD8XLF4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_716290</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the RPAP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369519.1">
        <property type="nucleotide sequence ID" value="XM_060511838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLF4"/>
    <dbReference type="GeneID" id="85395736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043175">
        <property type="term" value="F:RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039693">
        <property type="entry name" value="Rtr1/RPAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007308">
        <property type="entry name" value="Rtr1/RPAP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038534">
        <property type="entry name" value="Rtr1/RPAP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732:SF0">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04181">
        <property type="entry name" value="RPAP2_Rtr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51479">
        <property type="entry name" value="ZF_RTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RTR1-type" evidence="13">
        <location>
            <begin position="93"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="33064" checksum="052F4A597E8391B3" modified="2024-05-29" version="1">MATDTRPLKGILKKAAAGATASGSGAANAVLNPRKQDPREIALQHARIIQQRKDLELQILESLTELSEYPTERGSRTFSAANPSPRDVADFKAGIRLFQPSDYDDLIEERNVNGLCGYTLCAQPKPMASKGGEWRLVNFGKADFDIVNRKESEKWCSKDCQRRAMYIKVQLNESAAWERAGLPDIEIELYGEEKARQEDPATLASRDLASLKLEEGRRAADESATLALERGETRETGQPGNTFTLAIREREVKPPTEHGVFGDPDNSHLFVEGYRPGAGKAQAIAEASQFEAQRDQEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM16</accession>
    <name>A0AAD8XM16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_785092</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369925.1">
        <property type="nucleotide sequence ID" value="XM_060515623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM16"/>
    <dbReference type="GeneID" id="85399521"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="486"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="552"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="610" mass="69350" checksum="B12FE91FE69F6C8D" modified="2024-05-29" version="1">MSTRKVRVKKLSVKTLLPVLRETDIDAADYESLTTETQIATGVEAAEETEYHLQSILKEAGTSNDQEIPVPPPQESQINYDQLYPSNFQQPTSFIRFSQTVEECIGVSYDMTTEDDEFLKQYNATKKTVASQLSEDDFERIMEVFEDTASEQTPFASIDNTVVGYDLMVPSLASLGGNKLMAHSKHVFEHWKTRRQTLGNKPIHPSVKFETHQESDEADPYVCFRRREARQTRKTRQRDVQSAEKLKRLRRELEDGRQLIIQSYEREMLKRELLTFDRAIFEQRAKLKEMKVKLGIKTEDDDLINHKVCLTPSSGNSKTCVDRAQPPKKKPVEAPALQKPPGNHLRIAVRPDGRSMEADLLQLADKLAEKENELRADVESKVHNHRKWNQNHVDLTRDPLSPVKEQRMEASFRPAKTQYLMTPPASTSSESDAMDVDEEPEAVADRSDMSVFQFTAGGGKEKPSSSQAAFRRRIGRLGRLWIDRRGMSGMTTPPRVEGEEYTDRWKYDQDDEDEPQVYEVDPYDTRALKFRATIPLSQYVYQRRQLPHEGMVNGQATPQVAGAAGRPALPQPPTPQQQQQQAQPQPQATPQQPRQPPQASPPAQPAATPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM56</accession>
    <name>A0AAD8XM56_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_603953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369971.1">
        <property type="nucleotide sequence ID" value="XM_060507256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM56"/>
    <dbReference type="GeneID" id="85391155"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="46885" checksum="8163BAE260C7B614" modified="2024-05-29" version="1">MLALRDENAVNAAQAARLAPGKGQLAPKTPGARYPKTPLKIPLNDENAVGGAKSVLAAKSNANGNIQLTAKKQNLVTPSETRARAPLGNKTTNAKARATQNTGGKDGEKTQTKPTTTKKLKQRSPSVGPLKLEVRNDQTGPAEEPDVEYAPPTVKDLPYESDVLSNGDLTFEGLKPENMFKGYYNHFYNPLGEDGVRLQDRQHQERLQKALKESDERILRDIQEMDWSVSDVPETSAISQRKAPAPAPNPAVTRKAVGGAPKYPPTITSRRAASALSMSTGNTIRQKKAAEQKPTVRRPISSILPNTRPNRPAVAPKSSVAESAMGEAVSRNTLGYTKGRSASSFVSGRPTSAAAARSVSTDAKTTLAPKMTMRRDASPQKQRQEARNDSEELGKLQFLSIFDPAGDDEDDGIGSAGPRNEEFEDDEFEMKLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMA5</accession>
    <name>A0AAD8XMA5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate dependent xanthine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_726667</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370060.1">
        <property type="nucleotide sequence ID" value="XM_060512766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMA5"/>
    <dbReference type="GeneID" id="85396664"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF2">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT XANTHINE DIOXYGENASE XAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="26"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="409" mass="45985" checksum="487FB5C2168A8429" modified="2024-05-29" version="1">MGSLNSPSQGLSFKELPTSLRESSLIGAEVHLPSSMDVLDVDALSEEDLDTFRRALFENQVVVIKNQKGIAPETLPKLTKVFDPTASDIHSAGEKAVSDPRNILSAYKAGRIPRAPQVGIIGSGKFKNYEGVEELEVIHLDHTLFHEKPLSEQELSNGYTRPYRWHMDTPFYQRLPGEVTILHAVKVPNLPDQKLKFPDGKEKSIAAGSTAFFSGARAFQLLTPAEQEFALNTTVTYAPQAYEYIRQCKATEDGLSIPTMGKEIPMEQLSEWSWENVAEHPMVWRNPLNPDRPFLQVHGCCVFKLTTRDPVTGEVSIVDEVAKVREIVYSFQKRIWAAENIYTHRWEEGDVVIFHNRGVMHSITGQLAQYKEDEEKKRLMWQCTMTSGTAPQPFRKQPGVVETGFAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMB9</accession>
    <name>A0AAD8XMB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Spb1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_567446</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369984.1">
        <property type="nucleotide sequence ID" value="XM_060503956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMB9"/>
    <dbReference type="GeneID" id="85387855"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000004">
        <property type="entry name" value="AdoMet-dependent rRNA methyltransferase SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03163">
        <property type="entry name" value="RNA_methyltr_E_SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012920">
        <property type="entry name" value="rRNA_MeTfrase_SPB1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024576">
        <property type="entry name" value="rRNA_MeTfrase_Spb1_DUF3381"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028589">
        <property type="entry name" value="SPB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF13">
        <property type="entry name" value="PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11861">
        <property type="entry name" value="DUF3381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07780">
        <property type="entry name" value="Spb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="10">
        <location>
            <begin position="24"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3381" evidence="12">
        <location>
            <begin position="234"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase SPB1-like C-terminal" evidence="11">
        <location>
            <begin position="648"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="444"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="774"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="470"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="548"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="585"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="658"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="860" mass="97035" checksum="E27B98D119B124D8" modified="2024-05-29" version="1">MAIQKKHGKGRLDKWYKLAKEKGYRARAAFKLIQLNKKYGFLEKSKVVVDLCAAPGSWCQVAAETCPVGALIVGVDLSPIKPIPKVITFQSDITTEKCRATIRSHLKTWKADCVLHDGAPNVGTAWNQDSFNQAELVLQSMKLATEFLAEGGTFVTKVFRSKDYNPLLWVFNQLFTKVEATKPPSSRNVSAEIFVVCKGFKAPKRIDPRFLDPRAVFAELKDATPNNEAKVYNPEQKKRKREGYEEGDYTQHKVVSASEFIQTADPIAILGQTNQLSFDQPANGDVALAALDKLPETTDEIRRSCADLKVLGRKEFKQLLKWRLKVREIFGFPTKKTTQEKKSLQDQVGEEVAEIESMDEELRIQQELEALKNKDDSKKKKERRKENEKKQKDIVRMQMNMTAPMDIGMEQAGPLGPDAMFALKTADKAGGINRIARGKMALLKESEKKSKEAEAGIVYSDSESDPEEDRLERELDGMYDSFKERKAAADAKWRAKRAREEHGDGEWEGVSGGEQSDSDEDMEMDSDSSDDDEDENDDESGKPLVTDLDNTAENGNLSKRASAFFGQDIFKDIDMGDVDDEDWGVDDKPAEEEPKSKKAKTEKEDKKKAKEEKAKVAEEKQKAKDEKKKKAKEAKQKAADGFGSDSESEDDAGFEVVKNQEEDWENQEKRRPDGRLDIDIITAEAMTLAHQLATGEKTKQDLMDDGFNKWALKDRDGLPDWFIDDETKHDKQQKPITKAAAAAIREKLRAYNARPIKKVREAKARKKFKTAQRLEKLKKKSDSLANEEGMTEKEKAESIAKLMAKAGKVKRRPKPTLIIARGANRGIQGRPKGVKGRYTIVDSRMKKDLRAQKRLAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XME1</accession>
    <name>A0AAD8XME1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Abscisic acid ABA receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_421292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370091.1">
        <property type="nucleotide sequence ID" value="XM_060502983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XME1"/>
    <dbReference type="GeneID" id="85386882"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="42436" checksum="5C8F47880463D8DA" modified="2024-05-29" version="1">MDDPSTQTIKILTHLSKTLSLSPPQSTHPPATLTGLPTSHTGTAYLFLSVSAHHPRLQIHSYPAIHWARAYISNIPTPSAPISLPSSTQETARDIPVLGLLSDDLAGPAIRACVTKDLLHVRKFLAILSLVLEHIISSNANANSSSSSAPMSNSSTTMDLDAPEPTTTSTPPLPSCLLHGLAGTLYLLRLIRHWVPSSAPLVCGAIVHVSEYLLGPHPWTCPSRSPTSSQSYSHSHSPSSPSPPPPEDTHGTTHGDLGILTQLVLTSPPLAASPVLTSRLAALLDLQLPNGDWPAPSTTSPSPHSQPSQSEIQQALDAPPTPTQQKPAAKSSPRPPRGFASGPQGLVLSLLSLRPFFPSLHDRTDDAVEKAREFLWARAVDSDVPAEDVNLFYGSLSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNW3</accession>
    <name>A0AAD8XNW3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_600460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370798.1">
        <property type="nucleotide sequence ID" value="XM_060507035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNW3"/>
    <dbReference type="GeneID" id="85390934"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="7">
        <location>
            <begin position="38"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="30107" checksum="2586B11A1C3EFADA" modified="2024-05-29" version="1">MMLSGYIPGAEAVVAVGDIAKELKRKQAAAGTPGGFFWVLDPVMGDNGKLYVAEEVVPAYQSLVEHADLILPNQFEAELLSGVKITDMQTLQTAIRALHTKYSIPHVVITSVSLVSPDHPPSHLSVVGSSMSPSTGEPRLFKIVFPAIDAYFSGTGDMFAALMTVRMREAVIAASASTSADSEAQQLKDRESWLSGNEVDALDLPLAKAAEMVLASMHEVLTQTARGMQEVVAAAGGDALAETEEGRTKLHLLKSKSAELKLVRNLASLREPTVELRARRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPP2</accession>
    <name>A0AAD8XPP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_247979</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371442.1">
        <property type="nucleotide sequence ID" value="XM_060501915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPP2"/>
    <dbReference type="GeneID" id="85385814"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19528">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000004">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000001">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000003">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000048">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="5">
        <location>
            <begin position="80"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="192"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="466"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1731387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="755" mass="82982" checksum="1CB2DA1C9CBAF6AF" modified="2024-05-29" version="1">MEALQLFRGDTVLVRGKKRKDTVLIVLADDELDDGSARINRVVRHNLRVKHGDMITIHPCPDIKYAKRIAVLPIADTVEGITGSLFDVFLAPYFREAYRPVRQGDLFIVRGGMRQVEFKVVEVDPPEYGIVAQDTVIHCEGEPIQRDEEEGNLNEVGYDDIGGCRKQMAQIREMVELPLRHPQLFKSIGIKPPRGVLLYGPPGTGKTLMARAVANETGAFFFLINGPEIMSKMAGESESNLRKAFEEAEKNSPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLMDGMKARSNVVVMAATNRPNSIDPALRRFGRFDREVDIGIPDPTGRLEVLQIHTKNMKLGDDVDLEQIASETHGYVGSDIAALCSEAAMQQIREKMDLIDLDEDTIDAEVLDSLGVTMENFRFALGVSNPSALREVAVVEVPNVRWEDIGGLETVKAELQESVQYPVDHPEKFLKFGLSPSRGVLFYGPPGTGKTMLAKAVANECAANFISVKGPELLSMWFGESESNIRDIFDKARAAAPCIVFLDELDSIAKARGGSMGDAGGASDRVVNQLLTEMDGMTSKKNVFVIGATNRPEQLDPALCRPGRLDSLIYVPLPDQPARAGILKAQLRKTPVAGDVDIDFIASKTHGFSGADLGFITQRAVKLAIKEAITADIQKTKAREAAGEEAMDEDEEDPVPELTKRHFEEAMQMARRSVSDVEIRRYEAFAQQMKNAGPGAYFKFPEGEGAANEAANSFGDAGNDDDLYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPT5</accession>
    <name>A0AAD8XPT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_746681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371336.1">
        <property type="nucleotide sequence ID" value="XM_060513308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPT5"/>
    <dbReference type="GeneID" id="85397206"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="11961" checksum="1DCCFF4FFAA54218" modified="2024-05-29" version="1">MAAAAESAPYTGPSPREMIESHTLAQEIINRNNDACPILDSDELSLLFDFVKDPSQARSLLETRGLADEPTKTGSLVAYVISLHGTNNAALTDEEIQMLNQWFQNGQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ68</accession>
    <name>A0AAD8XQ68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_646065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371618.1">
        <property type="nucleotide sequence ID" value="XM_060509912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ68"/>
    <dbReference type="GeneID" id="85393811"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042281356" evidence="1">
        <location>
            <begin position="18"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="21293" checksum="4B345F22DE307F6C" modified="2024-05-29" version="1">MGGWLLHCLLQPRLALSKALITKFDIVWSLNALRDRKFGMFDSCESSFPFAQRVNRPPGTWVPPKDAAPGPAAGRQDHIGIRESSIPQSRSRVFSAPGSIVTCVGMQPQEHKDRKLCYWRTPQASVVGALNLLILSVDSAIMRPDNPPGTGRRATPVRISFQMAVLHTSFGTHELVLDDAESPEEGPHGKGSCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZJ2</accession>
    <name>A0AAD9CZJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_648119</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369184.1">
        <property type="nucleotide sequence ID" value="XM_060510150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZJ2"/>
    <dbReference type="GeneID" id="85394049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="9">
        <location>
            <begin position="168"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="659" mass="75182" checksum="124D3775C437DCA2" modified="2024-05-29" version="1">MKTQWKDLPPVPNSQEFLDIVLSRTQRRLPTQIRSGFKISRIRGFYTRKVKFTQETISEKLGLIIESFPRLNDIHPFHKDLINTLYDADHFKIALGQLSTAKHLIETISRDYVRLLKYGQSLFQCKQLKRAALGRMATLIKRLKDPLVYLDQVRQHLGRLPSIDPNTRTLLITGFPNVGKSSFLKSVSRADVDVQPYAFTTKSLFCGHFDYKYLRFQCIDTPGILDHPLEEMNTIEMQSVTAIAHLRSAILYFMDLSEQCGYSIQAQINLFQSIKPLFQNKIVFIVVNKIDVVKPEDLDAATQAQLQGLLKSGEVEMLQLSCNTQEGVQNVKNTVCERLIAERVSQKLNAGTNSSGNIGGRLADVMARIHVAQPGTSQPLQTFIPEGIKNMKKYDKEDPERRRLAKDVEAENGGAGVYSVDMRQDWLLADDEWKHDKIPEVFDGKNVYDFIDPDIDAKLQALEEEEERLEKEGYYESDEELDDEEEADILSKAEIIREKQALIRNEAKMKKRLKNQAIIPRKSQKVPLSQMDDALDQLGVDTTDIVNRARAQSRPRGRSSGLSRAGTEDVDMMDTDATPRERLRSHSRARSQSRAPIVNRREDGVQDDEARDKADRLAKLSQKKRNRMARQGEGDRHTTVSLQRHLVAGKRGLGKNQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1E1</accession>
    <name>A0AAD9D1E1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_747582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370427.1">
        <property type="nucleotide sequence ID" value="XM_060513459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1E1"/>
    <dbReference type="GeneID" id="85397357"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="15933" checksum="F4BE6B33A186482A" modified="2024-05-29" version="1">MEPQGIREEAFPARSRQETGTVNGVQTEVTSVSFSDKFVLTISQDGKLSQWIQVPLQASTGGMVDLSLPSTSRGLLPSVHLTPKTLLGGGGDERETLGQLYAAQIASLMSTRDPEDRRTLVVGLGLTKVDTEREAFFDTVELVQKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1Y1</accession>
    <name>A0AAD9D1Y1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SUZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_342547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370907.1">
        <property type="nucleotide sequence ID" value="XM_060502468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1Y1"/>
    <dbReference type="GeneID" id="85386367"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="2">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="3">
        <location>
            <begin position="196"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="25816" checksum="BE95F01A3FB9D6B2" modified="2024-05-29" version="1">MTFLETQPSVPLATGFKPQVKVLSRKPAPRTIARRDPVTGLLSHLSLADDDADDQHAEKKPQLTPEEIRAKQQRELEEKQRRYEEARAKIFGESNPSSGASSPSGTVTPPRGGGGGAENERGGGRGRGRGRGRGGGGGGYRGNSNRQDDLRRPGSSRSDAVRAESGRELYDPGYAPRGGFGMQKRGGGDGPHTYNTYNPHSSGRSTPRDVEDQPKQAIRAPRGPDGTGRGGFGFAKRGTKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D284</accession>
    <name>A0AAD9D284_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_376262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370654.1">
        <property type="nucleotide sequence ID" value="XM_060502681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D284"/>
    <dbReference type="GeneID" id="85386580"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="79" mass="8810" checksum="3EE87B949FB12F9D" modified="2024-05-29" version="1">MRQKKKRGGVGSVCKMCFARLAEESSAPTSLSQISAVRSTSPYTKVRYPPLCSPFRSCRSQAPSKQPRGRWMDGWMPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2G3</accession>
    <name>A0AAD9D2G3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371418.1">
        <property type="nucleotide sequence ID" value="XM_060513315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2G3"/>
    <dbReference type="GeneID" id="85397213"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107:SF1">
        <property type="entry name" value="WHIM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42107">
        <property type="entry name" value="YALI0D24453P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="64655" checksum="F8516A5E21B6E755" modified="2024-05-29" version="1">MADDDSSDLSSLSSLSPVPSDVESEAEPEPATKGDIRKFFPKLAKGKKATVATKEPSPPPRKRSPSPPHEKAFIDNPDIAFLVMFRSRFNDAFPKSLANFGPQELEQDIIGSPPGERVEAFLCALLFLLLNRKQDVKAGQYSKALDDALSAHKSQWPRSWEGVSPLSGSNTFHSITPTQRLSLLRAFALWSLSASETVKTIINKSYKGNRHDDDLNQPLSVQPWGSDSDKRRYFLIEGLDDTAFRVYRESNPAGFNRTWWSVAGSIDELRALCEKLETKDGGPKARKLADKMLAAIPRFEGTEEKRRRREYRQAQKARFKRPEPGFSSYEGRTRGKRIKYTYSDDEDFLTDSSNRRSARNTGTSTPAEPTGPVTTASGRQIRAPPRMNGSSAAGSVNGDSEDSRQPSEPTSGPGGRPRRAAAVNHGTNGWSSKGTRIRGRDSMDEDDDDGSELDLGDDEEEDHVPDESEEDDDELDEDVDMADEDLADEPRKSLIVKLSVKKSPTTTKTAMMTPAPEDEKAPMRDDEMVDEIVAKPRDKTPEPVINVATTKPPLSPAAVQTSLAFRGSPDKLQTMLQQVDVGVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2N5</accession>
    <name>A0AAD9D2N5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_565734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370955.1">
        <property type="nucleotide sequence ID" value="XM_060503789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2N5"/>
    <dbReference type="GeneID" id="85387688"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF7">
        <property type="entry name" value="SUCCINATE SEMIALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="67"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="60319" checksum="DA4505121B7D14F8" modified="2024-05-29" version="1">MISAVTSPVASSITTASTSSSGTSTAKSHKNSLVIHSLTPISPSFPLPFRLTDVDLLRRDCHIHGEWVSSLSNKRFAVLDPGTGRVWATCPDSARDDVNPAVKSAYVAFQGFSKHTPAHERARLLTSWHHLILASRLDLATILVHETGKPLTEALAEVDYGAGLVRWFAGEADRLEPPPPPPPPPTTTPQLPSPAASRVSSPTSDDDGAVPASIPATGVFPRKHGALLKQPIGVVLALVPWSFPLALTLRKAAAALAAGCTVIVKPSSETPLTALALACLADRAGFPAGALNVLTTSLGNTPVVSEALCMHPLVKAVSFTGSTRVGKRVAASCTRNLKRLSLDLGGNCPAVVFDDADLGQVAKDLAALKWRHAGQACVAPNRCYVQRRVYDVFSTLLVAEASKLKVGHGMAKDTTLGPLTTIRGLYKAEALCKDATEKGAVKLLGTGRREPGDGYFMAPTVLGGMTDSMLMCREEVFAPVLGLYVFDTEDEVVMRANDTPVGLAGYVFTKSNDRLWRMFDRLDAAVLGMNTVCLVTETPVPASNNGNGYTPAQATALDEFLVTKGAAMSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D358</accession>
    <name>A0AAD9D358_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Actin family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_565366</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371196.1">
        <property type="nucleotide sequence ID" value="XM_060503748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D358"/>
    <dbReference type="GeneID" id="85387647"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000015">
        <property type="entry name" value="Actin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000018">
        <property type="entry name" value="Actin-like protein (Centractin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1731141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="379" mass="42435" checksum="21E0861146A6D939" modified="2024-05-29" version="1">MTDSLHNAPIVLDNGSGTIRAGFAGDDLPKCYFPSFVGRPKHLRVLAGALEGEVFIGEKAATELRGLLKIRYPLEHGIVTDWDDMEKIWEYVYGEGLKTLSEEHPVLLTEPPLNPRSNRDTAAQILFETFNVPALYTSIQAVLSLYASGRTTGIVLDSGDGVSHAVPVYEGFAMPSSIRRIDVAGRDVTEYMQMLLRKSGYVFHTSAEKEVVRLIKESVTYVAHDPRKEEKEWANRTDPAKGVEYVLPDGHKLKIGAERFRAPEILFDPEIIGLEYPGVHQIVVDAINRTDLDLRKSLYSNIVLSGGSTLTRGFGDRLLTELQRLAVKDMRIKIFAPPERKYSTWIGGSILAGLSTFRKMWVSIDDWHENPEIIHTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3G7</accession>
    <name>A0AAD9D3G7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_167334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371689.1">
        <property type="nucleotide sequence ID" value="XM_060501430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3G7"/>
    <dbReference type="GeneID" id="85385329"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="12063" checksum="7967C1D424B21237" modified="2024-05-29" version="1">MVVVVVVVVGTQSLSLHRISMSRASLANSIKKRSSACSERWTGIKLHHDQDRFDIGPQSNRAEPKEEQTRRTLLSRVGHDGLIPSHGFGDSLTLRRRSCQSATALSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4A7</accession>
    <name>A0AAD8U4A7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000317">
        <property type="protein sequence ID" value="KAK1702205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357107.1">
        <property type="nucleotide sequence ID" value="XM_060511039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4A7"/>
    <dbReference type="GeneID" id="85394938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="160"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="633" mass="71703" checksum="A7824C532F77C96B" modified="2024-05-29" version="1">MNLCGLCGVYKIVVEAVIDGRLPALFQGARNETERDQILDELVVGSIGLTTANTEESMDLLVKGAYVRVSLFIAPEEQSVFRVSSNGDEEVGFPKETQYGPSTDSIRSFARARQWLRQCLDHHDCGKNRDLFYPRRLLDLRDDQVRLIETTKTNDFQGPYVCLSHRWGDAKFSRLISTTETIHSRMEGIKWEEIPKTFQDAITICRRLSVDYLWIDTLCILQGFPEMSDKQKRITGADFAAENSAMARIYRNSYFTIYASVSTSMASGIFSSRRYESHQIKVSDVSGNESILRIRETTSHFTPPTDLETRGWTFQEYLLPCRVIEFGPFDISWKCNQTYVCECRHNTGAAHWREELARRALPPQNAAEAEEWWAGILRQYTMRHLAKDEDKLPALSGLAQLYRQLTRDTYLAAARAPSWSWASLDIVNDAQCRFWWPRVSLSTNPLMYGDGATPRPVCTVYEASCQPMTDGPFGEVIGGFVDLGVMLISARIGIKPQGNNSFSTAGHVAWTLDYVEDGTDVQVCLADCSLDDDGLQVEDEVFCAPIVETLSESESDRGCLVLKRMSEGSEFRRVGFAVLRKQNPSWDRANGPLRMDRGWGYNEPDLTTPEYAEKVQSYALSYNSNVLCRIRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U672</accession>
    <name>A0AAD8U672_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_658551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000329">
        <property type="protein sequence ID" value="KAK1701924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357078.1">
        <property type="nucleotide sequence ID" value="XM_060511043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U672"/>
    <dbReference type="GeneID" id="85394942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1701924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="36565" checksum="4FE7AB057DAB3BE5" modified="2024-05-29" version="1">MFAQSLHAVFPALKGPVNLPYEIFLLIVEAMISEAYARARQEKVIYKIDFTNGRYQSVPQSSFSVVLESRKGVKIQMQRWKQIRDLLRVDGTSRCLVGRVFVTNDMIWPQTLTPETLLCFPNLQEIWVQVEQKFTGIDPRVSFHDSHDDDMPLDTQILPELGLDASGHDMKTLKTQLRVAEKRGINVHVTTGRAWTQSSRAKTLRLFLKDGAVRMQLVDPHCDCYLELAEDLRALGLTLEQAMQQDQCFTRLGLWYLRYLGCHGGAFEEHALQFHFQRLFVSLAVDCSLHRVLDLFSYHKLTVDAVSQRLLATSIVTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6M3</accession>
    <name>A0AAD8U6M3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_592469</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358377.1">
        <property type="nucleotide sequence ID" value="XM_060506538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6M3"/>
    <dbReference type="GeneID" id="85390437"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000032">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="425"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="255"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="358"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1708695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="642" mass="69556" checksum="2EEDCAAF1E09BCE8" modified="2024-05-29" version="1">MAASFARSSLITADSTSTVCSMVSESPALSAGHSDAASGTGTPNSSPPASRPRSPELKHHESLDASDLEPLEPLNVKNVCFVGAGFVGGPTAALIALHNPDLTVNVVDLNADRIAAWNSPHLPIHEAGLPKIVRISRDGTNGATAFLPSVSNSVKIAPRKPNLTFTTDVQRCIGEADIVLICVNTPTKTYGLGAGYTADLSALEGASETVAKYAKDGAVIVEKSTVPTGTARMIREIMAQYQPDAEFEIVSNPEFLAEGTAVRDLMHPDRILIGSSTTPAGVRAANALKGVYAAWVPEQKILTVNTWSSELTKLVANAMLAQRISSINSISALCEELGADVQEISQGIGADTRLGKKFLHAGVGFGGSCFEKDILNLAYMARTLHLDTVADYWMGVLDINKYQRERFAQKVHRALNGNLRRKKVAILGFAFKENTNDTRNSIAVHIITELAHEMPNEIAIFDPGCDPVEVMEEVRQSIPDERVVERVKVHTNWRDTVHGSSAICILTPWYHFRYPKQAQSTARRSSVWSSPEASREEAKAFIKESLSEMDIVELEKFVSRTSTNTPTDPLKRMKAEAECQEGCKGCNFDAANEDLGDPVDWEWAASVMKRPRLVLDGRNVVSVPDLEKLGFQVQGIGKGLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6U6</accession>
    <name>A0AAD8U6U6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_143716</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358561.1">
        <property type="nucleotide sequence ID" value="XM_060501288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6U6"/>
    <dbReference type="GeneID" id="85385187"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF123">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="58"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="501" mass="55504" checksum="4613F7F50FA84CFB" modified="2024-05-29" version="1">MLIWPGLEKEDMDVSSNETTEGGFGSTQMQALSHESLANMMLGVIIAVLVVTTVFVGLRIYVRSRVIKKWGADDTMVTLSFATVAFHGIMLCLGTRFGLGKHVWMTQAQTIEKAQKLAMFIVMIYNIAFVTIKIAFLLQYRRSFPLLMVEMLCNAGIAFLVLFGVSLMVSAGITYSLVLKREMTDSPVSVLGWWLANASMHLLTNIFIFVLPLPLLGRLRLRRGEKLALVISFALGLLICAVSIIRIAYLPGSFDMVDMTYDGISIILWSVVELSCAVICCCIPTLRPLVERRQRGLADDYDDATIFGGGMFREDMTFGEGSQRVRPDMRGANNERISSSISCASETGMRKPGPTFFWLRTRKQSDHSSINGLDDIAPMPTHAGPMMAAAAAAMPVVEVHGVRRESEYGIIVVESERVEGGVEREREIPRRASVRSSLRSDSSLGVALRRDLSVRRHMSIALTERDSDDDVYYFGVNEEDVDLECPTPLSPPPKCRKSTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Q4</accession>
    <name>A0AAD8U9Q4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000247">
        <property type="protein sequence ID" value="KAK1705174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357558.1">
        <property type="nucleotide sequence ID" value="XM_060509744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Q4"/>
    <dbReference type="GeneID" id="85393643"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="69" mass="8131" checksum="DC9E415655524DEA" modified="2024-05-29" version="1">MEYNFLIQCIIIEIYSIFRLSFLTLKIYISRLLTLVNIIISLAAFSCSWFYMSMSHLHTPILGFYTLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAV0</accession>
    <name>A0AAD8UAV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-x8-C-x5-C-x3-H type zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000267">
        <property type="protein sequence ID" value="KAK1704304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357411.1">
        <property type="nucleotide sequence ID" value="XM_060515092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAV0"/>
    <dbReference type="GeneID" id="85398990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25542">
        <property type="entry name" value="zf-CCCH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7923" evidence="2">
        <location>
            <begin position="78"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="394"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1704304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="461" mass="51738" checksum="4212865FC72CD002" modified="2024-05-29" version="1">MDETEDLSAYVQQLELFRRNDYTRDQMIQDLLARHGQLQQAYREKCDDYNNERESRRMWQTKANNLGKDVVALNKANESNPFVFVIIDGDGAIFQESLLKRGAEGGAEAGYLLSTEIKNYVTEAYPEAASEDWNIIVQVVLNMDGLAKKLHASGIIPFTTSERTLIEFGRGFGRAQPLFSFIDVGSGKESADHKIREMLRVMVRIGQCKHIFFGPCHDNGYLPVLEPYKLDDKVASKFTLIETTPAEEGFKQLKFHRIIFNSVFMSEKLPERVQRQTMGMPSMLPPPISSAPTATISAAAKPPTGPYHTNSNSANNGASVEPPRVTSPISSGSQTPASSWSTLTRVSTAPKPIDIFSTKKVPQPKYYLMNADSQRIDEPLPKVDPMVEKRFNARMTETGKKFCNNYHLHGECKNPVCSYIHGDKLSASEMVLLKQKGYHDISPKPRVKCFEDGSMKIIDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB05</accession>
    <name>A0AAD8UB05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_634215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360721.1">
        <property type="nucleotide sequence ID" value="XM_060509083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB05"/>
    <dbReference type="GeneID" id="85392982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF7708" evidence="3">
        <location>
            <begin position="180"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="476"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="701" mass="79115" checksum="65078B1F5368C52B" modified="2024-05-29" version="1">MESNPSKDVRGSGFLDSLPSRYMEDQGRNLHPIYRDPILRNPSLATVTASSIDDSNETLKSGSAQNLQALKGLASNKTQHFQQVMDEFVKQQTDSGKPDLFRRMKDHFGRQEAEDPAPRDQSFNIRGTHSWDEVVKQIQEAKTSYESKAAGKSGMATKAGRFISDHAKYVDPWVALIPSSDYSSVVSGGLKFVLGAANAQANIRTKIIGAIERLPDDLETTRECLARFDQALNQYYWEALQMKALNLYVGILTAIEAMLAWLDQHAFKKMLKSLMLQDNYGLKVAEYVENIKKYSVDLRQFASECAEFAVVQTFKTAKEIKPFVEEAFVNSVRNFEQGRRTEGTVQSMTAAVVAHGSTLALLSDENNALRSIALESDWKLANLEREFANFRAVQGAILEGQQQMMLLSQQQAQQMSSSQQAFLRWPQQAPQQTQLTRQHLQARLDVSIQRIEWSLESVRSIGRVEGISGSDLVKKLTQIRKFRAWMQSNQSQVLLLRIYEPGKLITPLSSVCSSLLASLKDLEPTVTLHYFCGILRKDSEQGRFHLLRSLIVQLLEKFPAEQAFAMDVDYARQSEWGFNVLRQLFETALLSMPGAVIFCVIDGCSRCTDEDELQDTMHYLLWVCQEQSPVVKLKLLLTSPVPQHISQRIPGEMVVFLPTVTRQERSGLTYGLQPTTPVRRQFDRAQSGSPPAVFFCNEDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB53</accession>
    <name>A0AAD8UB53_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="3">FBP aldolase</shortName>
            <ecNumber evidence="3">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_638351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2 3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359488.1">
        <property type="nucleotide sequence ID" value="XM_060509361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB53"/>
    <dbReference type="GeneID" id="85393260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050246">
        <property type="entry name" value="Class_II_FBP_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30304:SF0">
        <property type="entry name" value="D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="31281" checksum="7A683FBB237DE64A" modified="2024-05-29" version="1">MTRPSLAENRTMKIVNAAHEGGYAVAGFCCYNLEAVVASVRAAEATSSPAVVQLFPWAMEYAGSALVKAAAELCHSASVPVSLHLDHCQTPDLVRRAADIPDGFDSIMVDMSHYEKEENLALTRELVDYCHQRGIATEAEPGRIEGGEDGVAETIDLEGVLTTPEQAEEFVATGIEMLAPAFGNVHGEYGPRGIKLEYDRLENTNKAVGDRVRLILHGADPFTEEIYNRCIKAGVTKININKGINNHYVPTQETARGRPITATIEAGTKEMQKACETYMHWFGSAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBA6</accession>
    <name>A0AAD8UBA6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_656176</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 11">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359852.1">
        <property type="nucleotide sequence ID" value="XM_060510854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBA6"/>
    <dbReference type="GeneID" id="85394753"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901430" description="carbonic anhydrase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="8">
        <location>
            <begin position="40"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="38994" checksum="B4A44E0DB26E6012" modified="2024-05-29" version="1">MSSRLITFGFFAASVSQVLASCAYGTHLDPRAEEGKVKVNNFAYTGSNGPLNWVALDATANQLCATGTTQSPIDMVAGSFNVLPGSSINLEIPDMAEGTEFENLGTTVEVIAKGGSMQVGGSNFTLQQFHFHLPSEHLDAGKSMAMEMHMVFEGANQEIAVIGTYIDLEQGAAAAAPAAPVTEAAPVAEAAPAGGNATAERRTKLARRAATGAAAEAPKAIPAMGTNPIKAEAASSSLLETVFSSLDAIKEPGTVTKTGALNMQEVVTLLSAGSFQSYMGSLTTPPCSEGVQWLVSTQRLMVQPQTFTAVRDVIGFNARFPQNTLGQANIIQVAQQSLTSANIANPVAAAPAVAAPVAAAPAAPAAEAAKEAAPAAAPAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCT6</accession>
    <name>A0AAD8UCT6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TAM domain methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_755063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361621.1">
        <property type="nucleotide sequence ID" value="XM_060514564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCT6"/>
    <dbReference type="GeneID" id="85398462"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="40074" checksum="75533879488C689B" modified="2024-05-29" version="1">MCADNNTNPVAQPSTAAAQATQPNSTTDHEVVLIAEVHDESDAASNLGSSVASSSTSVSSSILEYRMENGRTYHAYKDGKYFFPNDERENDRLDLQHNLFILTFDNKLATAPPNDPGSKVGNVLDVGTGSGIWAIDFGEEHPDAEVCGVDLSAVQPEFVPPNVKFEIDDIDQPWTFSKPFDYIHSRMMNSSIKDWKAYIQTCFDNLSPGGYLELIEFDAVPTSDDGTLKPDSAITKSATLLFDAAAIIGQPFEDISRMKDVLIETGFEDVHKQLYKWPTNSWPKNPKYKELGIWNHENAIAGWEGFCMAPCTRIHGWSREEVLVLMAEARKEFKDRTIHAYFNIWSIYGRKPLVSESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD57</accession>
    <name>A0AAD8UD57_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_587142</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I NDUFA13 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360688.1">
        <property type="nucleotide sequence ID" value="XM_060506013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD57"/>
    <dbReference type="GeneID" id="85389912"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009346">
        <property type="entry name" value="GRIM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06212">
        <property type="entry name" value="GRIM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1716758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="13762" checksum="5C98B77A61F9A3DD" modified="2024-05-29" version="1">MPQDMPPVGGYQAVQYKRNLPARGFRPGTMLIGMGLVMGYGWYQLTKGIREANELAREKMWARIHLIPLLQAEEDRDQVRRWYADQAREKELLGENTKVYHNERFVRPTFALAPQSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE65</accession>
    <name>A0AAD8UE65_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_585694</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361303.1">
        <property type="nucleotide sequence ID" value="XM_060505869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE65"/>
    <dbReference type="GeneID" id="85389768"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000010">
        <property type="entry name" value="Fungal transcriptional regulatory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF28">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="862" mass="95112" checksum="6F1ABE7A0B4E6128" modified="2024-05-29" version="1">MTAPITQQQSAQAKDAAAAASVRKRRRRAPAGGAADDCFTCSKRNVKCDRRRPYCSQCLEIGNECSGYKTQLTWGVGVASRGKLRGLSLPIAKAPPVAGVAKKSPSRPRANSTATSAGWADADDMSRRSPRNDAGFSPEHVVSTPTTPYPHSYDMLSMSHPEHTPSMTAGHWGGLPYSNSMPTDGPNYRKLGAHLGPLPISSALSSSLESVSDGDYMSPISHSYSRDDIPFLHSPNVMYDGYSTHGSPVPQSPISAILIDQRAAPTSCPSLVYAPSEHSSSLTSHMDNFESQLSQKLMRECDTLSVPEMDAYSTSCNSNGHVWTSPPPEEMSPHHSDHHASAQWPTMFEPQAVHVNSDLIAKMPFFMDYYKNIMCPGMVFMDGPSNPYREHILHLASSSQSLQHAICALSACNLRMKRRLSLGQDTRELSEKLMAEKSTAESMADAQPEDQSLSEEYQHRNLAVHLLNQQLNDPAKSSHDSVLATILLLCHYRMVESGIAKFHTQFAGVKKILSMRRSQNLAPSRDSAWMEAIFTYFDAISASINDREAQLNSTFYGVMPDAQLLPPGAENLVGCDRELFKTISKLGRLNLLSQHRSVQNLVTSPMARNIPSRSQSPLSSPLGHSFKSNLNGLHHQQLGDIYSLPGHRFDGNGFGSTLDDDEFVSSTLCSSATYDDNRNNFWREWKEARVALQSWEFDSARLHASLPSPATPAQVRDLGSLSEAFRYAALLYTERLASPNVPSTHSNFQNLVSQVVYYATSLEAGSQAEKFLLWPLFVAGSECVNELQQNIVRSKCRDIMARSGYMNNLAALDVLERLWAGEWKDNEPRSPAAVKLEAMRRGPFNWTRCIGGPGVEVEWIMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEB0</accession>
    <name>A0AAD8UEB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_635975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360225.1">
        <property type="nucleotide sequence ID" value="XM_060509220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEB0"/>
    <dbReference type="GeneID" id="85393119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004932">
        <property type="term" value="F:mating-type factor pheromone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000366">
        <property type="entry name" value="GPCR_STE2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02116">
        <property type="entry name" value="STE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1715082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="80" mass="9108" checksum="40D8FB4B9481D97E" modified="2024-05-29" version="1">MMPSMRLIVASLWAHITAFANNTVRMTLLALIFTSTDWTNFYTRFASDYSRVAAAEFHLRIMAESTSVILHILVQVSLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEH6</accession>
    <name>A0AAD8UEH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_628279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362772.1">
        <property type="nucleotide sequence ID" value="XM_060508687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEH6"/>
    <dbReference type="GeneID" id="85392586"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="23153" checksum="0E5DB22420590F8D" modified="2024-05-29" version="1">MGWYEITDDYIKDSKINFPVCETLQVRDVYGGTQRTIYRVDQSGRQFPVWTVNENNENGVLAIVSADPRARDPAGNAVGIIKYHTMSSRTQITLRGSELSLGLTDYSHGHEINFNGCNYRWVMSKSTMSTTTLYLKTDGNRILARWSGKPEGRAGDSSPVFELFVPPQTLDMDLLVVTGLAAAGYWKKADRLRSPISKILKIMGGLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEL1</accession>
    <name>A0AAD8UEL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359959.1">
        <property type="nucleotide sequence ID" value="XM_060510846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEL1"/>
    <dbReference type="GeneID" id="85394745"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="23469" checksum="14108C6F3309EB6C" modified="2024-05-29" version="1">MCEVKQIRESCIRCSKVVRHVTDMKPCENHIQVRTKTGTLAHWCKGKITRNIHETYFPTRHPCNDASHTAALSRWTSQPARQPPPSGPQRVERLSDLGIRRGKVVTQEPQCQNEACDSLCCLEHFEAWPEALPEAVKQPQTKYIGHQLDPAKPSYDFDVALGVSVARLETHRVFRQFNQWLDVPSFRVRRLDDTDSFFDDDTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFP8</accession>
    <name>A0AAD8UFP8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_629775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362248.1">
        <property type="nucleotide sequence ID" value="XM_060508782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFP8"/>
    <dbReference type="GeneID" id="85392681"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF56">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0045">Antibiotic biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="4">
        <location>
            <begin position="13"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="26961" checksum="902ADC4E008D3CB4" modified="2024-05-29" version="1">MLGHIKDLAEGKEVNGKGRIYRTQKAQTYHTDESDIVGLLCLHQAMEGGESQVVSSHNIYNTLRRERPDVLRQLCFPHWFYDRKGETSEGQNEWMRTPGYYWYKGRLSMKWDSYYVGALHRFWDAGLLPQYTDAQREAIQVMEEMCRRLSLEMTLQQGDIQFVANTHNLHARSAYKDDNDVTKKRWLQRLWLATSEEEGGWPLPFADSRYSKRGDVQVNETPESYPTEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFR6</accession>
    <name>A0AAD8UFR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YesU protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_629913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362278.1">
        <property type="nucleotide sequence ID" value="XM_060508787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFR6"/>
    <dbReference type="GeneID" id="85392686"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015305">
        <property type="entry name" value="DUF1961"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09224">
        <property type="entry name" value="DUF1961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042258644" evidence="1">
        <location>
            <begin position="17"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="26229" checksum="A67F1084FD5069A5" modified="2024-05-29" version="1">MRTLTALLALATSTMAETLLYSNPLNSTADVATWVAEGPLTVAAVNNTLELSGGGNPDDYFVYWVPEVFPDGIRITWEFSPRNEPGLAMFFFGAATVADDGKGSIFDPSLKPRNGSYPQYHSSDIRTLHASYFRRRWPEERAFHLANLRKSPGFHLVSQGADPLPPVPDAAGAFYKIEVIKDKREVKFRINDLPIFEFYDDKSTGPIIRDGRIGFRQMQPLVARYRNLQVWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG96</accession>
    <name>A0AAD8UG96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit K, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_586394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361038.1">
        <property type="nucleotide sequence ID" value="XM_060505942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG96"/>
    <dbReference type="GeneID" id="85389841"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1718038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7594" checksum="C1AC58FA130DEC96" modified="2024-05-29" version="1">MVQMYTIAGRQIGSHYLAMGVLATLFGGASYGLSGSKPKATATPPINASSSDEADFIKKFLDSADKDEKAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGA2</accession>
    <name>A0AAD8UGA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_382922</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363777.1">
        <property type="nucleotide sequence ID" value="XM_060502720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGA2"/>
    <dbReference type="GeneID" id="85386619"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18573">
        <property type="entry name" value="ABC_6TM_ABCB10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000095">
        <property type="entry name" value="ABC multidrug transporter Mdr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000218">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="189"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="509"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="102"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="749"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="755"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="767"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="790"/>
            <end position="799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1723722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="799" mass="86243" checksum="FF4BD393F2A7F251" modified="2024-05-29" version="1">MAMGVVRSAVLLPHRAGSCPTTLASLMTTLPGLRSTSTIPPVLQHPLLSQIRSFSSKPVQSLTAARSAAVQRSSLHRPVPLSQKPQLPGPIAILRYFSNGFSKQRDSQPTTQTPATRGGDKDANQTESTSRDPEQPDDFQKSERAAKAAQVNLSAKLSKEGKSQGGKAGFSEIWRLIKIARPELRWLGIAMIFLVISSGVTMSIPFSVGRILDMATKDPTEDARLFGLTMPQFFTALGVILTVGAMANFGRVILLRIVGERVVARLRSSLYRRTYVQDAEFFDANRVGDLISRLSSDTVIVGKSITQNISDGLRALFSGGAGFCVMVWLSPKLTGLLLIMLPPVAVGAFFYGRAIRNVSKGIQKNLGTLTKIAEERLGNVKTSQAFVGEVQEVGRYNRQVKKIFALGKKESTIAATFFASTGWAGNMTILAMLIVGGNFVRDGAMTLGDLTSFMMYTAFAGSSLFGLSSFYSELMKGVGAASRLFELQDRKPGISQTVGLKVKSAQGPIRFSNVSFAYPTRPAVNIFNDLNFEIPSGSNVCVVGPSGGGKSTVAGLLLRFYNPISGSITINGVDISKMNVKSLRRRIGMVAQEPVLFSGSIADNISYGKPNATRAEIIAAARKANCNFISDLPSGLDTQVGARGSQLSGGQKQRIAIARALIKDPDILILDEATSALDAESETLVNAALTSLLRGRNTTISIAHRLSTIKRSDLIIVLSNNGGVAEIGKYTELSADKDSAFSKLMEWQMSGGDVPDPRSSDRAHITEEEEIESDLEREEGEEEVEEQLQEETREKEARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGQ3</accession>
    <name>A0AAD8UGQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_755442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361221.1">
        <property type="nucleotide sequence ID" value="XM_060514611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGQ3"/>
    <dbReference type="GeneID" id="85398509"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36460:SF1">
        <property type="entry name" value="UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="185" mass="20868" checksum="6D661D57F99668C4" modified="2024-05-29" version="1">MDFAPYQSSPPERERALSPPLASPRASADIRRPFSPYGQPSPPPLQHPQPQRGWQPNLPGSYPTADAHREGVSEFDTSLGIRLDYEAALAYLAFPPLGAILLLIGERNSDYVRFHAWQSALLFTAVMIFHLVFLSWSKFLSWFFFIGDLFVMVWLALKAYQDADTLDRFEVPVLGALASRILDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGS7</accession>
    <name>A0AAD8UGS7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_741895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363676.1">
        <property type="nucleotide sequence ID" value="XM_060513095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGS7"/>
    <dbReference type="GeneID" id="85396993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="32736" checksum="21A3A2415B78D0C7" modified="2024-05-29" version="1">MNPINTKPYILPPVATWLITGCSSGIGQALAALVATTPNHRLIATARNPADLDYLPDDDVNLLKLALDVTSPTSVKEAFKAATAYFGEDFHLDVLVNNAGYSLSGDTESATEEQAHQEIETLFFGTARMTTCAIENMRQSETRRGGIIFNISSLAGQCAFPGHAYYHAGKWAVEGWTESVAREMHPDWNINFCIVEPSGVQTNFEGHSKARTEPHPAYAEKDMPARVLERYVEMGIKSGTLTKPSAIADAIFGIASSKKRIPLRVPLGEPAWGFIKQKHETCLRDLEGVKDLSLLVFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGV5</accession>
    <name>A0AAD8UGV5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_720156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364107.1">
        <property type="nucleotide sequence ID" value="XM_060512251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGV5"/>
    <dbReference type="GeneID" id="85396149"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="577" mass="63087" checksum="0A7E7BBFCB048793" modified="2024-05-29" version="1">MSANVWPGADSSSQHSGQLSQKDLVLDQQMIKHLLNRYGQDKLNLLIQETTGPQSDGASIVSSAQSSVLSDDQSSMWDTQSIRTFSDTSSITGSIISNVSRGTSKILGRRSGSSSAAAAAQAQAAQQAAQTQQDSESWNGIDVPNSSNTASDAASISTSASKQKGAFMCGFCKEEDITKTCTRKNDLKRHIEDFHNVNAQWFCRHRGCQMVFDWQGAYKTHLKQAHGGSRMSLDEAKVNLCPQVVFACGFDNCLQVFEAQGDSDASATFKEYVSHVVKHFDEGSNSGDWSYSARIRNLLRQGQVQSAWNESMWNEASRTSLQWSPQTSGILRKRLECRHVGDVKLLVQYAMMLGSDPSSIGKFREDFVTPVADTCTLHMPGHKSRQPTIAAPPEQPTDPFSFKISRGANPALAAYMASQRRVYVPRQQRVVRPPQLHHPHQQVPTSNLMASHSRLSQSSHSSHTSSHHGHPQVHHSNQSHSTLGHFFQAMPESQLYDPNSNAQGFGPSSGAMHHNGIIADDMQSLRSMGGAPESTDVEMQDGLMPDFSSPYGQHSANLTSPSINGHPDGFFPPGQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHM1</accession>
    <name>A0AAD8UHM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_454147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361814.1">
        <property type="nucleotide sequence ID" value="XM_060503170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHM1"/>
    <dbReference type="GeneID" id="85387069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="33369" checksum="85E6587182B28200" modified="2024-05-29" version="1">MATNGHSANKFLIWGGEGWVANHLKVLLEGQGKEVYTTTVRMENREGVLAELEKVKPTHVLNCAGCTGRPNVDWCEDNKEATMRSNVIGTLNLTDACFLKGIHCTVFATGCIYQYDDAHPIGGAGYLETDPANFKGSFYSDTKGHVEEIMKHYKNCLILRLRMPVSDDLHSRNFVTKIAKYDRVVDIPNSNTILTDLLPASILMAEHKDTGIYNFTNPGAISHNEVLSLFKEIVRPDFTWKNFSLEEQAKVIKAGRSNCKLDTTKLEKKLKEYNYTVPEVHDAYRGCFERMKANGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI48</accession>
    <name>A0AAD8UI48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_323238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364767.1">
        <property type="nucleotide sequence ID" value="XM_060502386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI48"/>
    <dbReference type="GeneID" id="85386285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="158"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="34920" checksum="C930FD8348941A7A" modified="2024-05-29" version="1">MTDAKRKQSGGGGGHPAKRSKGGQGSGKWQTPQHKAKVASLQDKGVALGVGDKGIWVTFARGMDGKSISEFSALCDEYAKTLYGIVPPGEEVESDEEDEDIEASIKKELDGISDVNKGKTKRTFKAIKAGIECVFFMKTRDPIDPVELCRKMCVDASVCTDLKERKTKYINRLTPVTSVDKASENGVVRVARNALAAHFDLVGETAQATGGDVEKIEGGSDAQAEKPTCTYAIRPSIRSNNSLDRDTLIKQIASVVSPRHKVDLTNADKVILVDVFQSFCGMSVIERSDWDDLKKLNVNELYKASPGAKANRPAPKEGEDKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI49</accession>
    <name>A0AAD8UI49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hsp90-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_455177</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361759.1">
        <property type="nucleotide sequence ID" value="XM_060503181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI49"/>
    <dbReference type="GeneID" id="85387080"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000023">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000083">
        <property type="entry name" value="Sensor histidine kinase/response regulator, putative (AFU_orthologue AFUA_4G00660)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="577"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="1106"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="463"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1237" mass="135598" checksum="2963D933074F9BA8" modified="2024-05-29" version="1">MSEAQREREVQRYLQSWQVAQGSSFNVALNVDSIAAPDLHGNGYKPKASADKALTAFAQLAVLKLDVKRAMVSLIDTTTQTILAEGTRSVQLGDFEHLQDSNSSGLNDNDDQNGDNELWLGATILSRPDAVCEHSMVNTCTGLDQKGRPYTATGLIVNDCRLDPRFAQRPYVLSEPGVRFYAGVPIISRSGHKIGSFAVSDERPHNGLTAEEIRFMQGVAQTVMEHLEWARDRVDRFKGERIVRGLATFIEGCSTMNEDSNSVKDDIPRSPSTVRPPDMPLISTRRPMPRSNSYFRNAEALVRSRESSASRQQSDTTEPPGPSTENPPSPKKAYQPRVDGLSKLFNRAADVLRHSTLADGVAFFGATATSATPGSQSRSGRSQSSDEEDVTRPATSGSGLDSSDSDTSPSSRPCKILSFSVADERARARIEQGPALSLGILEKYFSMFPMGKTFSFTEAGLGVSSGDDSASDRETMGVDGASRPDKSEGRRRKVKMVHEELLKKIPGAKTVVFVPLFDYGEDRLAGGCFLWTSVTGRMMNLDQDLSYLRAFSNSIMTQVGRINSQKNEAAKTTFIASMSHELRSPLHGILGSAELLQDTSTDAYQSGLISSIATCGKTLLDTLNHVLDYSKINRLGRAQMRRRAKQTQSRPTAITSDSLESLSMSSVVDLAVLVEEVIDAIAAGHAFKKLVGVGSLDGPKPSISVKETNNVRSVGNFQAPGAKGPVSILLDVDPKIPWLVKAQPGALRRIIMNLFGNALKYTTQGYVLVSLTGQTRSGGTKIDAMIRVADSGKGMSEEFQQTRLFLPFSQEDSFQPGTGLGLSIVKQIVDSLRGSLEVRSEQDRGTEFDVHLSFTSASDDTEDPREPDEAMRRAVNETRGMKIVLLEEERTSDTPPMTKHAAKLNQILTETCSEWFKMKVVKETPSEPPNADMYLYSEPPSVEVLEKRFKDNSRRSPSQRKAPFIIVCPTAEEAVHILQDHSKLLLDFSEIVEVIPQPCGPRKLAKVFSHCLKRVEELERTQAMARNTSGLLAPIPLAPDSPTPGTNEIRQVERVGTPLHQQARPEQIEPALGAQPLIKPLGAMALSPALNGGQPVLVPQKNVTLHVLLVDDNQINLKLLVMFMKKCGFTYEQAENGQEALDRFIEASSSSIEASASKRRRFDFVLMDISMPIMNGFEATKRIREYEREHRLQATTVVALTGLASADARRDAETSGFDVFLPKPVRFAELQKLLTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI97</accession>
    <name>A0AAD8UI97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pfs domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_752362</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364842.1">
        <property type="nucleotide sequence ID" value="XM_060514189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI97"/>
    <dbReference type="GeneID" id="85398087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="397"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="691" mass="77710" checksum="333AF03B91E4C3C1" modified="2024-05-29" version="1">MAPNHRKRPRPASSNEDDGDGRPAKRPTTVGPVAQAPINADQVLPKLPRDAYDVGWVSALHLEMAAAIAMLDFRHEPHAQKEDDSNVYVFGSIGLHNIVIACLPSGEYGTVKAAVVANNMHSSFPSIRIGLMVGIGGGVPGTVDIRLGDVVVSNPTRDSPGVVQYDFGKAINNGRFEGIGSLNKPPTFVLAAVSALRAKHETQPSQIPSILDDMKQRNTLMVEYTHQFVDEDLLFESSYEHSGENCDNCDRSKLILRDPRATNDPSIHYGIIGSANLLMKDAKRRDQLAKDHGLVCFEMEAAGLMDNFPCLVIRGICDYADSHKQKRWQRYAAATAAAYARELLLLTPVQENFAIHTQVEIRDSDTSRTKRGELLDSLKFDQIGKRHANIKANHARTCEWLLNHPEYTAWKDTKKYKQHHGFLWMKGKPGAGKSTIMKFALDRASGRTISFFFNARGESLEKTTLGMYRSLLHQLLRALPDLQVLLDTTVISPSDQQGITAWDLETTQVLFRRAIQNLRQRPLTCFIDALDECEAAEVRELVEVFEDLGQYAVQNDLRFYAFLSSRHYPYIDVQYGQKLILEDQVGHGNDLAKYVCTKLKAGTGPQSDEIIAEILRKASGVFMWVVLVVDILNKEYLRRRLFAVRGRLREIPSELGALFKDILTRDQENKDDLLLCIQWLLYSKRPLKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIC5</accession>
    <name>A0AAD8UIC5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364872.1">
        <property type="nucleotide sequence ID" value="XM_060514163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIC5"/>
    <dbReference type="GeneID" id="85398061"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="39877" checksum="4901D6DE348F9316" modified="2024-05-29" version="1">MLQNRCDCTRDKPDINRAISVGEDAVERIPKDWRYTALILRQLAVSRAQGVAVGSNTLTRIMGRRFEQTANIEDLDRAVGVLTDTVPLIPNNQMDYVVGTSYLATLLGIRSEQQGDVDDLNASISYTKSALQLMSNDDFDRPVQLYNLENRLAERAQYTGILSNLDDAVDYGQQALHLFLGIRFSMGSKNPEDIKQAIDLSRQAAKEVDGDEMGMRAALANVLSNMREENYNQYGEAANLDEAFDVLGDVLQGGLPDTLPERGYLKFGLEFSLGDVLHARSFHAGDATDLEKSRGAFQWAWNSRTAPLTIRIEAAVRAAEVAKERLDNHNSLDSGTLSMIFASTHGSSIILMSSPEPDDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIN7</accession>
    <name>A0AAD8UIN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_629587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362298.1">
        <property type="nucleotide sequence ID" value="XM_060508766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIN7"/>
    <dbReference type="GeneID" id="85392665"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877:SF2">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="20154" checksum="BD29F07F519E6F0E" modified="2024-05-29" version="1">MFYQYCAMAEQQFDPISSRKGCTLARAKTDHVPHIQSMTRAAYSKYIDRIGKEPAPMKADYYELIKTQLVYILYDDENDAVVGAILLRLDPSANALHINNLVVAPEAQGRGYGRVLMKCAEDVARDSRCTSLQLYTNVKMYENLILYPKMGFVETERRTEDGYERVYFRRELDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIS9</accession>
    <name>A0AAD8UIS9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_783371</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362549.1">
        <property type="nucleotide sequence ID" value="XM_060515585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIS9"/>
    <dbReference type="GeneID" id="85399483"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18099" checksum="EB7916918231CDC0" modified="2024-05-29" version="1">MTASANDTNVPAAVAEPRTPTSTPASGSASPGVAPAHQCRQCRASFCQPLGCGHVYCDECAGPRHECPECNRHPVVSPKPSTEVSKILPPFAPCINSLLTKGFPLLLKKPPKTTYPPEDGLFDLVFQKRIDSRIRTIYYVSLCSFWASVLAGILCIIALILETSKRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ39</accession>
    <name>A0AAD8UJ39_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">glycogenin glucosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.186</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_580093</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Self-glucosylating initiator of glycogen synthesis. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23360"/>
            <dbReference type="Rhea" id="RHEA-COMP:14604"/>
            <dbReference type="Rhea" id="RHEA-COMP:14605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140573"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56560"/>
            <dbReference type="Rhea" id="RHEA-COMP:14606"/>
            <dbReference type="Rhea" id="RHEA-COMP:14607"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:140574"/>
            <dbReference type="EC" id="2.4.1.186"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.186" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363782.1">
        <property type="nucleotide sequence ID" value="XM_060505313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ39"/>
    <dbReference type="GeneID" id="85389212"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008466">
        <property type="term" value="F:glycogenin glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000092">
        <property type="entry name" value="Glycogenin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="299"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="585"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="416"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1723727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="788" mass="86447" checksum="E9B2E81234C03F6F" modified="2024-05-29" version="1">MAPLRGGEQVYATLLLNDTYLPGALVLAHSLRDAGTSKQLVVLVTLDTVSAEVITELKAVYDHVIPVPRIRNARPANLYLMNRPDLHSAFTKVNLWRQTQFSKIVYIDADVVAYRAPDELFDIAAPFSAAPDIGWPDLFNTGVMVLSPSMGDYYALMAMAERGISFDGADQGLLNMHFKNTYNRISFTYNVTPSAHYQYVPAYRHFQSSINMVHFIGPDKPWFQGRQASKGDSPFEDMIGRWWAVYDRHYRVAETAPAPPQEQQPQVQEEHTPAQQQQMHQEPQVPEIVQYFTKGEFQPQAAQAASTGEHYHGAFPPRSHGGIHYQTAPPSSGHPAHGPSHHDAHDAGPSQPCVHHEQPYHGQGSQPEIAYQAGHSLPPSSESFGAFAGTQAEARSEQISAHEGRGESVPVEQPREPTPPPAWDAQRQPPPADSRPEALNFPSQTYEMSQDPAPFVPPQRYPSPPRNMWYEIPKDKPTQKPRHLFPWEINQPKPTRVFTADLAEPEAEESSSTPTGEHAASFTASSTSQAPAEPSLLGSSTTGQKSEPSTPATPTIKVSPSDPWTAFTRTNAWDEVPEIERYVEGLQKHRRGKSQGSVGISDGKTAKEHGLKLTDFPSVVDRPSLPVTPAPIRRPKFWGGGPRPGDGEDDEELPVAQGVPPQTDWDPSAQLQELAKQQSEALLKKLGGGEGEPEGVSREIPKRSLPFSSEGVFPPTYVAQSSKGVVLSPQPVKGSATTSVLRNLGGEQAQIQEPAYQGPGTAWERGEGAPLWETPALPTEEQRDVLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJK4</accession>
    <name>A0AAD8UJK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_577280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365131.1">
        <property type="nucleotide sequence ID" value="XM_060505006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJK4"/>
    <dbReference type="GeneID" id="85388905"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="34719" checksum="F62FCED17F70872E" modified="2024-05-29" version="1">MPFPLPSISYPPSRDGFWNPVTATINWCEEDYYVTSYVAEFVNTFTNAIFVYLALVGISSCIRNSHPRVFLVAYVGYMTIGIASVVYHTSLKYWMQLFDELSMIYTTCILFYAVFSHGKSLFGQALLGTFITSLAIFITVYYHYLGDPVFHQVMFGVLTATVVFRSMYIMEKILRPKSTPQSKAELLDTQLLKKMWTLITCGLVSIAIGFLAWNLDNIFCSHLRQWRRELGLPWGVLLEGHGWWHLFTGIACYINVTYGVWLRYCRDGKKEEVVLAWPSMFGSIPTVERAQHGGHPSKPGSKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKI1</accession>
    <name>A0AAD8UKI1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_576021</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365686.1">
        <property type="nucleotide sequence ID" value="XM_060504877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKI1"/>
    <dbReference type="GeneID" id="85388776"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
        <property type="term" value="P:post-translational protein modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12610:FF:000001">
        <property type="entry name" value="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="471"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="22">
        <location>
            <begin position="21"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="23">
        <location>
            <begin position="543"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="729"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="732"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00059243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00067960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1725631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="749" mass="83667" checksum="66C5D298425966E0" modified="2024-05-29" version="1">MTAQSLGPLSGGSKENTRTVLRVTILSLIAAAAVASRLFSVIRFESIIHEFDPWFNFRATKYLVANGFTKFWDWFDDRTWHPLGRVTGGTLYPGLMVTSGAIYHALRALTVPVDIRNICVLLAPAFSGLTAYAAYLLTNEMTTSPSAGLLAAAFMGISPGYISRSVAGSYDNEAIAIFLLVFTFYLWIKALKLGSMLWGALCALFYGYMVASWGGYAFITNMLPLHALTLILMGRYSARLYVSYTTWYALGTLASMQIPFVGFLPVKTSEHMPALGVFGFLQLVAFIDYVRGAIPSRQFQTFVYTFLAATFGLALAGLVALTSLGYIAPWGGRFYSLWDTGYAKIHIPIIASVSEHQPTAWPAFFFDLNMLVWLFPAGVYLCFQNLRDEHVFVVVYALFGTYFAGVMVRLMLTLTPIVCVAAAMAASQILDTYMVAKSPNPEDYKTEDAVEGASKKTAKQSGLKSTSKPVVGIYTFLSKAVVVGGMSIFLLLFVLHCTWVTSNAYSSPSVVLASRLPDGSQHIIDDYREAYQWLRQNTKEDAKIMSWWDYGYQIGGMADRPTLVDNNTWNNTHIATVGKAMSSREEVSYPIMRQHEVDYVLVVFGGLLGYSGDDINKFLWMVRIAEGIWPEEVQERKFFTPRGEYRVDDQATDTMKNSLMYKMSYYNYNSLFPAGQAQDRVRGVRLPDVGPKLDTVEEAFTSENWIIRIYKVKDLDNVGRDHQAAAAFERGQKKKKAIKKRGPRVLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKR7</accession>
    <name>A0AAD8UKR7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_777880</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365143.1">
        <property type="nucleotide sequence ID" value="XM_060515491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKR7"/>
    <dbReference type="GeneID" id="85399389"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="807" mass="91430" checksum="A288AAE25D08D872" modified="2024-05-29" version="1">MQSHVDVDSPPTGSDTPRKTRRVCVPKACQHCARSKQRCDGANPCARCQSRNRSCLYATDDRRNPDSFQDFRAPASDTGEVFDGFSSSGLPNQIATINRTEVLPEPQVGNSQEQLYQGPDPGPDARDNFQAALWNQDGLQLELDPLFCTPSQWYFPFSTANAWLSWDDILNNELGTQETTRAASMADEEGLRTQLISEHASNERREEARDCSVHAEVDGAVSETAVQEPTPTSLLSEDTPRAIFTNHSQLSSTFANAFRRSSAFSRDYDDSAEIEQNQTRRKKHFVTHGLEDLSRIAGSPFHPEGVDENEDWDLEAYDHVPSLSPHAYSILQTQFTKLNADTDYCKAFTDKSFPSQQAIDVYIQSHFEHYHPIWPLLHQKTFDPEHVHWILLLAVEATGCGFSKFGTISDVFLLQELLRRSINLCLDLDPEPDAASELCLTQAVLLSQIGLMFSGSMSFAEHAQRNMSLLATLCRRAGYFSESQSLPEGFAPLPANWKRWICAESKRRLVHLSWLLDGQLGLFFDLPPTIPTDLLLLPLPSDEGLWASSSAGLWADQASRSPTNDSLLREHLIHFRRDEKVPQGLSSLNRLFFTFAVYRDSANNQDAIHYLEVLRSDEDIQPPTDKIQRITLQHNHAFSLLLHMPLRVLTAFSGWGVSPQVREAADRRLALWLRQNEAKARVIVYHAARLFSYIRNYPTCGHHENNALLYATLSMWIHTLFNRHQTSALRTLRLDKPNHQEALVQWLSVDFDFRLYVAGIGDLNDERASKRLVQESVRILTRKSGWSLGLAVSMVMRAQWRSNRGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKX2</accession>
    <name>A0AAD8UKX2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363468.1">
        <property type="nucleotide sequence ID" value="XM_060514357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKX2"/>
    <dbReference type="GeneID" id="85398255"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041911023" evidence="1">
        <location>
            <begin position="21"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="94" mass="9668" checksum="012F16AD8D584CCB" modified="2024-05-29" version="1">MQFSTIMTTLFLAAATSVAAKKHSELHCITASGSGQFIVGLPNNDVTRKTCPGFCSDCVLSNSGTTITCRSPGKLMEGGDFSDACIKNGGSGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMY7</accession>
    <name>A0AAD8UMY7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_236439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366856.1">
        <property type="nucleotide sequence ID" value="XM_060501844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMY7"/>
    <dbReference type="GeneID" id="85385743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12108" checksum="00BC581D467DC874" modified="2024-05-29" version="1">MKIGSGYSTQTFRQLCEVNYPSGAAYGNPALYDILKVYVSTFEECMALCAAHNQAYGSNLASGDVKAGGYCRSVAMIKLPGEYCYLKNGTGKMDTQGHAKDFVTGVVVSGLPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN00</accession>
    <name>A0AAD8UN00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylserine decarboxylase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_624028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364114.1">
        <property type="nucleotide sequence ID" value="XM_060508423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN00"/>
    <dbReference type="GeneID" id="85392322"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF13">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="46718" checksum="88D0EDF1BAE1E17C" modified="2024-05-29" version="1">MSLSVTTAPDEVTSISPISHLDSKASGTTQEAIQKTSTSNDGYLRFNPVIVMLIGYLEQVSPGGLDSAVRSAHKKNPAFMSKLAIKDANCFLIFANDLLKWVPHENFGGKDIYDILCTFYFVLDQPPLRKLQTPIRPDSQGLTWLSSWIVVYAQLIGQFLDTPASITPSSLQSFTNSPPYRFHEAEIPKGGFRTFNAFFTRRLKPGLRPIASPDDDSVIIYPADCTYDNSLANQSVARISPNGSVEIKNVRWPISMLLHGSEHAADFDGGIWMHAFLNTTNYHRQHAPVSGRVLEAKNIQGMAHLEADTVGDGQVRMMGGADASENPGYQFLQTRGLVVIENPVLGKVAFLPIGMAMVSSVELFVEEGDVVRKGDEVSCFRFGGSDVICIFQKRAGLRVEDFVPTRGEFSNYGSIMARAPTGGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNB7</accession>
    <name>A0AAD8UNB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_274770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366032.1">
        <property type="nucleotide sequence ID" value="XM_060502086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNB7"/>
    <dbReference type="GeneID" id="85385985"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="60279" checksum="0ACBAB0706628493" modified="2024-05-29" version="1">MSRLCGMRPEGLTVDSRFSPLPSMCFFDTIIIPLPAWIRLTVTFALFHFIVPVLIVDKIKRYTVKKEWQRHAQLSVYFFSILVVFLMEIMEIARLAEIRYAIGLLPFVFAGCGVCAVMQATRGIKGKIRNWQVANIIFWIMSVAVTIIKILTIQRSSMRFPEFRRMGTDYPTTHQVQDLAVIAGFYVLLLINEIALFFQKTWEETVDAENIKKLRLTRSISDQARYDLTRAIEEGYYPSGVTYLTLRLEGESQSEKAVSKDDILKKTASMDASIAGSSSSEKTAGKRLMDEDSIEPVPMIPPSFRRNSERWSSAMTLKDAAGDDMNEKVGGKDNNNKKRGSERWSNAVTVKESTALRDGHDKRVSSFASPMVADIDETTPLDPPSTSSSRYEDEHAAQKAMLLDSPFPMKELPDRRSFMLKPSRPNTERWSNAMTLRGEPSSGSGSQEPSPKEHKQYMPSAPPAAATAPTTPERRASASERNMMRRYSDASTRSIRRFSARSDLREAAATAAAFVDGDEPLTSPTEAHPLQPNHHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNI6</accession>
    <name>A0AAD8UNI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_544599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365385.1">
        <property type="nucleotide sequence ID" value="XM_060503440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNI6"/>
    <dbReference type="GeneID" id="85387339"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="31080" checksum="5D708B1092B0F8AF" modified="2024-05-29" version="1" fragment="single">ATPSLPYFEHAWSVLSTIGVFNVFLGLLIIGITSFSKLTVVPIVSSAAGAIANGLYFHAYYDKPYPLAKRAAAAAIGDICWLIQEAGLPFYSFIILNRLLRGTKRRVFHTVFWSTLVLVTAVKVVIIYYRLLRILREDDSLQGIIIRIHIAYFGLFAVSECVSAYFLLRIFAEVRKSSKEAGLRTSFIRYLMRSTEIRVASLAVAAAIRVITHSLNVWQSSPATRYVDRAAYALGCFFPVIMYVDLLASKLQFTTQTNDPSFASDRPLRGAVSSGKTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNU6</accession>
    <name>A0AAD8UNU6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_717459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367872.1">
        <property type="nucleotide sequence ID" value="XM_060511949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNU6"/>
    <dbReference type="GeneID" id="85395847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000015">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010568">
        <property type="entry name" value="PRK13961.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="10">
        <location>
            <begin position="17"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="33466" checksum="E8E4C923AE9905C1" modified="2024-05-29" version="1">MATASVTSVDLTGLKKIGQGKVRDVFEVDEKTLLFVASDRVSAFDVVMKNGIPDKGAILTHASAHWFKVLTDRVPGLKTHFITLDPPAGLPAADAALIKNRAMQVRRLKVIPLEAIVRGYLTGSAWNEYKSKGTVHGIPVPAGMQQSQAFATPLYTPSTKAEQGEHDENIHPDEAVKLVGAKYAHRVEELALQLYAAARDYAAERGIILADTKFEFGVDPDTDEVVLVDEVLTPDSSRYWPAAGYAVGRDQESFDKQFIRNWLIEQRLKGKEGVALPEDVCKATAEKYKDVFVKLVGKSFDEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP39</accession>
    <name>A0AAD8UP39_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_349077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364684.1">
        <property type="nucleotide sequence ID" value="XM_060502511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP39"/>
    <dbReference type="GeneID" id="85386410"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="19239" checksum="9DFFEC97BDB81B19" modified="2024-05-29" version="1">MVRLRPPAWFCALCSGFPGGIGAPPRTPSTSMLTVEPHQRRSHPSLLPTRNLRRPALADRHNGGMPHNHQMQISTARLSEKRRFWRNGDNQGNGVTNHTLCPPIHDSTLAPFNGYLAGLGLVRHPGHESIHTQKGFEIKVENIHRGTRAPVSQLKSRHRCVSGTAEASDVLMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPA6</accession>
    <name>A0AAD8UPA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_363990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364025.1">
        <property type="nucleotide sequence ID" value="XM_060502598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPA6"/>
    <dbReference type="GeneID" id="85386497"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="26167" checksum="C8DD0C21216EC7E1" modified="2024-05-29" version="1">MHFRRHAGSQRPEIGEAAWSLSRQRQGRGQWGSVGWRTVSNSVPYGYNVSFNSMMHRTWLLESIKCPKQRRKEGNMFLSTQLHDSLRPLSMHACIPRRNSEKNSSTAPAISWHTYWSVYLLFLLLMLYLDPTPPESVIPPQANENTADLPGPWSDQPFCSPLPQTIHIRSSLPDSLLGFPSVFVFDNSRLGLLPRKFRVSTPAGPISHADLVLGQIDPQSARLALPLATQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPG9</accession>
    <name>A0AAD8UPG9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">DNA-directed RNA polymerase III subunit RPC3</fullName>
            <shortName evidence="9">RNA polymerase III subunit C3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_789977</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368247.1">
        <property type="nucleotide sequence ID" value="XM_060515703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPG9"/>
    <dbReference type="GeneID" id="85399601"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055207">
        <property type="entry name" value="POLR3C_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013197">
        <property type="entry name" value="RNA_pol_III_RPC82-rel_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008806">
        <property type="entry name" value="RNA_pol_III_Rpc82_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039748">
        <property type="entry name" value="RPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12949">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08221">
        <property type="entry name" value="HTH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05645">
        <property type="entry name" value="RNA_pol_Rpc82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22536">
        <property type="entry name" value="WHD_POLR3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase III subunit RPC82-related helix-turn-helix" evidence="12">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III Rpc82 C -terminal" evidence="11">
        <location>
            <begin position="171"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase III subunit RPC3 winged-helix" evidence="13">
        <location>
            <begin position="495"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="366"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1728192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="657" mass="73519" checksum="7033C42734293FA0" modified="2024-05-29" version="1">MLVTKHGAELCAHLVNDICGELPARILAVLFSKGRSTIAQLIQTTGLTPRQLRHGLALLVQQSLIYHESDSNNKIGTYEANPDGCYNIIRAGKIIEMVGTEFGPAEQEIVQTIMQLGHARVSDLLQAFEGRNGTGLNGDHATNGHVNGNGSKAKVNGHGPSHAAQELHAVLNRLIVAEIVDQVGPKTFRNPEDVYREIEEEVTKTAPGERATARNKELMQTEVSKRLREARDESKKLKRQVGRGNVFSTKRRKLANGRGARESADWDEDVPEIDSHIVLRVNTEKCLVELRNQKLAQYAADAFGEVTGLVYHTALRLLTQQVSRCQLDPRIDSDNDADGPGSNSRQVTVTSLEILENLDESIDVSHGVGKASADQIDVRSAEKVRATPGQPMYDSDDSDYEPPMAPRASARPNMNGAADSGVSEDEGPRAASGSREVRFEDGPIFGASRIDQMRQHLLLLSESRQGFLRHCGSQGRGQWTVDFKPLIEGFKQTEVDAVIEQSFGRHGLRLTRIMREKGKLDEKMLPSLALMKKGEVQGKMLAMQMAGFVDVQEVPRDASRTATRTMFFWFFDIERTEAQLVDDYYKAMLRCLQNLEVHRYRERNILSFVERRDVKGKEEEVMTAEHYNKYSKYLELQSKLLAHVMRLDELVGVFRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPL6</accession>
    <name>A0AAD8UPL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_650265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366617.1">
        <property type="nucleotide sequence ID" value="XM_060510358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPL6"/>
    <dbReference type="GeneID" id="85394257"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001332">
        <property type="entry name" value="Similar to ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF2">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="30616" checksum="C35F71CDC92B2FBA" modified="2024-05-29" version="1">MAQKSPTIEVTNLSYNFQDSSSGLKNISLSVPSRSRTLLIGANGAGKTTLLRLLAGKRLAPQGGISIAGIDPFKDGLEGVTYLGLEWVLNPIVRTDIGVLELLRSVGGDAYPDRRDELVSVLDIDTAWRMHAVSDGERRRVQLAMGLIRPWTILLLDEITVDLDVLSRAEFLAWLRRETEIRDCTIVYATHILDNLAGWPTHLVHMHLGTVREWDTADKFIEGLDGSTGNSTLGELVLGWLRKDLKDRGPRSQARVAPEGKTYATGGVGGYGDESDKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPM2</accession>
    <name>A0AAD8UPM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364205.1">
        <property type="nucleotide sequence ID" value="XM_060510521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPM2"/>
    <dbReference type="GeneID" id="85394420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="546" mass="50645" checksum="5E4752EEBB64D313" modified="2024-05-29" version="1">MEPLGDRIAELSRVVVNSSTRRRAEHVTRVMRSNLIFALVTAIAAISSAAPAPQASGAPPSGTGLAPPPHGSGAPPSGTPPPRPSGTGLPPSGAPPSGTPPAQQQRRFRGMMNRRQNSALPSGPPPSGAPSGAPPSGTPPPRPSGVAQPSGGGHGGFGAQEAGAKPTGAPPSGAPPSGVRPSGPPPSGVPPSGAPPSDAPAPTGNAKRAEPSGAKPSGPPPSGVRPSGPPPSGAPPSGLPPSGPPPSGAPAPTANARRAESAPAGPKPTGPPPSGVKPSGPPPSGAPPSGAPPSGAPPSGAPAPTGNARRAESAPPAKPSGESGPPPSGVRPSGPPPSGAPPSGAPPSGAPKPTNAKRADESAPAGPKPTGPPPSGVKPSGPPPSGAPSGAPPSGAPPSGAPAPTGNARRAEDAAPTGTKPTGAPPSGAPPSGAPSGTPPPRPSGAQAEGAAPSGTPPPKPTGTPTGPPPSGAPSAPAQKRAESAPPSKPSGTPPSGAPPSGTPPPRPSGAQAEGAAPSGTPPPKPTGTPTGPPPSGAPPAPTQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ4</accession>
    <name>A0AAD8URJ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_749448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368218.1">
        <property type="nucleotide sequence ID" value="XM_060513766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ4"/>
    <dbReference type="GeneID" id="85397664"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF17">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY FAMILY (AFU_ORTHOLOGUE AFUA_8G05690)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="25694" checksum="CA13CEB09FE39E46" modified="2024-05-29" version="1">MGLTVLPALIPDISQVYDAYFAAFEGSVILDILFPTGIDEAFREGHTKHTVEYWHKTSTQYTIKCVDVDTGEVVGMALWDAFLKERTPEEYRSPGAVWLQGEQRARADELINPLSAAKEKLWAGRKYVYCHIIAVKPEHQRKGVGALLTKWGLDMAELAGLPVYLESSEEGFGLYKRLGFEVLQDKIVHRGGLVGKDKDVEVPLMVKMPSAAKGLTFEEWRAQGYPSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US68</accession>
    <name>A0AAD8US68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_262429</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366381.1">
        <property type="nucleotide sequence ID" value="XM_060502005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US68"/>
    <dbReference type="GeneID" id="85385904"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="117"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="33703" checksum="D71E9ADD362AB9FC" modified="2024-05-29" version="1">MPPRIVSPLHAATCCSRTLRPSTNPTSLVSLFAGLSIGTRNASILASLSDNKGAYNKRIRLGRGPSAGKGKTSGRGHKGQGQHGHVKPWFQGGQTPLIVQRGTKGFDNKRAPVMSKLNLDKLQQWIDAGRLDPTKQITVKEIIESGLIGSVKDGIKLLGRGKTDLRQPIDIMVSRASASAIDAVEGNGGKILTRFYTKQSIKRLLRGESQNTDKPLPVGKEYVESILSEARKKTFLYRLPDPTSREDIEYYRDPAHRGYLSHLLKEGESPSLYFKVPLARKRIEHADKESRKETKKVTRDNTLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USG0</accession>
    <name>A0AAD8USG0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_614037</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367109.1">
        <property type="nucleotide sequence ID" value="XM_060507801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USG0"/>
    <dbReference type="GeneID" id="85391700"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07956">
        <property type="entry name" value="Anticodon_Ia_Arg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000058">
        <property type="entry name" value="Mitochondrial arginyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="13">
        <location>
            <begin position="163"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="12">
        <location>
            <begin position="649"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1727054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="766" mass="85629" checksum="91B76A22D262B75F" modified="2024-05-29" version="1">MDEWLSDSGWPSVRNFFSAGDKHRPQPSAQRPLPLLAFFLSRPPAAQSPSSSLLMTSVARFIFSSSSSSSLRSAHVYPTSLRRGASSAASAFVHYPPRRRPPTSTTRLYSSTTPNRSTLAKPPPAPTISLATMADQITAQLEKLSVSKLESYPGCYPEVNPIDVYRSHITSLLQPVTGVESTIIYNALQWTQSLDKGDLVLAVPALRIKGKKPADLTAEWLDKIPESPLIEKPVSFQNGTFLQFWFKPGPLSQLLVPQVRSRGVDFGKNPNNGLKNTEDKSQGKKKIIVEFSSPNIAKPFHAGHLRSTIIGGFIANLYDGAGWDVTRINYLGDWGKQYGLLALGFERFGSEEALAADPINHLYEVYVKINKDMADEKDQITAKEQAGEDVTALKDNSLDEQARKYFKAMVDGDDKAVAQWRRFRDLSIKRYKETYARLNIHFDEYSGESQVSEADMEAAAKQLEDMKISEESEGAVIIDFTKHVPGKPGKSLERPIIRKKDGTALYLTRDISELLHRQKKYNFDHMIYVVASQQDLHLKQLFKIIELMGHGETANKCQHINFGMVLGMSTRKGTVKFLDDILRDVGDKMHEVMKKNEAKYAQVAEPEATADILGISSVMVQDMSGKRINNYKFDMDTMTSFEGDTGPYLQYAHARLCSIFRKAGVAEEEIAKADLGLLTEKHAIELIRVISQYPDVVQNTLKTLEPTTVLTYLFRLTHVVSSSYDVLRIVGSEAELQKARLALYMAARTVLFNGMRLLGLSPVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWT5</accession>
    <name>A0AAD8UWT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_111863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368599.1">
        <property type="nucleotide sequence ID" value="XM_060501096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWT5"/>
    <dbReference type="GeneID" id="85384995"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04486">
        <property type="entry name" value="YhcR_OBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834">
        <property type="entry name" value="ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42834:SF1">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214747" evidence="1">
        <location>
            <begin position="17"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="298"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="64263" checksum="25FCFD9AE45E3342" modified="2024-05-29" version="1">MKVTSLFLSAAGAASALTIAEINGNKFLSPYKDQSVTNVTGLVLAKGPAGIWIRSTTPDDDAATSEALYVYGSTVGANLTVGDLVTLDGKIQEYRSATNYIYLTELSSPKNVVVVSKGNEVTPLVIGVDTLPPPTEQYSGLDGGDVYAVPNAVANISTENPILNPALYGLDFWESLSGELVTIKSPVGISRPNQYGDTWVIGDWPVTGGNAHGGLTMSDKDSNPEAIIIGSPLDGTKNPESKMGDELTEITGIVTNAFGFYRILPLTGITIAKNATNNAPATTLVSRGDCRGITVGDYNVENLSPTVAHLPSVAAHIVDYLKTPDLVFVQEIQDDNGATNNGVVSSNLTLSTLTAAIETKSGVAYDWVVIDPVDGKDGGQPGGNIRVAYLYKPDVVELYKPNPGGALDANEVLEGPALKYNPGRIDPTNTAWDASRKPLVAQWRAVNGPVNKTFFTVNVHFASKGGSSSLHGDPRPPVNGVVNPRIEQAKITGSFIAEILALDANARIITAGDFNEFAFVEPLKVFASTSGLIDLDEAVGVPVEERYTYVYDMNAQELDHMFVSPALANKNGTAYEHIHVNSWELYDDLVSDHDPSVALFNVCGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7Q6</accession>
    <name>A0AAD8X7Q6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_594785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000255">
        <property type="protein sequence ID" value="KAK1704895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357505.1">
        <property type="nucleotide sequence ID" value="XM_060506736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7Q6"/>
    <dbReference type="GeneID" id="85390635"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022085">
        <property type="entry name" value="OpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053204">
        <property type="entry name" value="Oxopyrrolidines_Biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797:SF6">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38797">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12311">
        <property type="entry name" value="DUF3632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1704895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30918" checksum="A93173FEBDADEEA2" modified="2024-05-29" version="1">MNNLLPKTDAPKVGVNDAIAALPAYKSLGSFIKTDGTTDKKALENTVDEFKDLAKKSESQIEDFLWDTYNAIFAVAKQTAPEKQAPLVDFLQRLRETTVTASDGQPLKFNNQVVWKDLPTFGWVARDLWNFDTSDTSASAEEKASWTNLSAFAAQLTARADLTNPQDPFDFSLYGLWALRAAFEEEDAGSEGGKDVIATRIAYQWTNHAVGALHDLSMKKRNFEGKSGKPGSKYADREWKGLNEERYGLWADSITSISQTASDDEARALAKEAAAKMTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X821</accession>
    <name>A0AAD8X821_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arginosuccinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_644581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000265">
        <property type="protein sequence ID" value="KAK1704416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357428.1">
        <property type="nucleotide sequence ID" value="XM_060509763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X821"/>
    <dbReference type="GeneID" id="85393662"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:L-arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814:SF1">
        <property type="entry name" value="ARGININOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="3">
        <location>
            <begin position="85"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Argininosuccinate lyase C-terminal" evidence="4">
        <location>
            <begin position="354"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00032749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1704416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="488" mass="53803" checksum="9F564A1AFEEEE6C8" modified="2024-05-29" version="1">MPGLAVSPENLPVPGRDTYYWLGEINKASAVINSSEGLLEQDVVRRISRGLQKLLDSGDEPGAPRPSLVITFEPLFIEAAGVEATLLHAGRSSQDMLATVCTAILRDAVLKLTAQLHATTIRLLEMAETHASTLVPNYTNGVAAQPNSYGHYLLGHIAGLHRDAERLRQFFARLDRCPMGTTVLNGTSWPLNRDRMAKYLGFTQVVDNAYDAAQITMAEMPVELGGIASQIALHTGAYIQDVMNQYAQPKPWILLQEGGENTYVSSAMPQKRNPGLLNNTRSDASYIVTLGLGRAIQGHNLPPGYGDAKDLGHNLDVINGTTKVLAQWQRILNALIIDGKRSLKELDLDWTASQELADFLMREYKVPFRVGHHFASETVRHAKAEDLSPSNFPYAEASKIFKETLKHAGLEEGSYQFLSEAEFQEALDPAGIIKHRATSGGPQPKEMERMIGNSKQTLQDLESWIKERQSHIVSSLQELDKAFQDLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8A7</accession>
    <name>A0AAD8X8A7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_642542</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358149.1">
        <property type="nucleotide sequence ID" value="XM_060509622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8A7"/>
    <dbReference type="GeneID" id="85393521"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="5">
        <location>
            <begin position="644"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1707933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="799" mass="89861" checksum="A90892F096562052" modified="2024-05-29" version="1">MAAKYAAQDLSDAALGGPIGLKDGYFVDNYGRTLTLHGLNISGASKLPTTPNGLSHLTDGFFEHRTVTFIGRPFPLGDAPLHFRRLQAWGLPLIRLLVTWESIGHSGPDPETDVDLEYIDYLRQLIEIMPKYGIKCFICAHQDVWSRFSGGSGAPGWTFEVAGLDVEAFTETGAAYVHGQDDLRRATAPVNEKEPSGPFVWPSGYQKIAASTMATLFWAGEALAPKLQCQRSKNGSDETVSAQEFLQSAFIEAFGRLADEVAGLEACVGFEPLNEPHRGLVNLHGFDGWNYDTDLHIGYYPSLTQALALASGYAQEVNYYVKSWPFPTRISHKTVVDPKGRSAWLAAKPSASEPQNYGLGECVWRAHGVWEWDEAKRGPKILQQDYFEVDHRPGREGKPLEWYRDFYGPFLKRFSERVSRKSSRQFCFFEPIPNEFVPPWVGQDGKVDEAGQKQTYATKTIIDTPRPGNLVFAPHFYDLNVLFSKHHSWMSVNVQGLSRGMFILKALYFGAKALRQNYRTQLANILKYGQKSLGTHVPALIGEVGIPYDINGGEAFKTGNYDKLRELMHALVSAMEDNNLAFTLWNYNPDNRVEYGDGWNKEDFSVVNGDTEAKPGHILPDYANAAHEDNELYRGGRVLDVIIRPYAVKIAGRPVRSDWDPRTLHYEFEWTSEAETDVKNSKSQPQKSRTTEIFVPKYHYAQRNIDIKVSDGEWSYDPDLATLYVQHDGSKSTHRLTIDITNIPRHLMETVERRRRAFPPSFPLSLISPSTELAIGELMMPMLLPGLLVIFLAVVTMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8G8</accession>
    <name>A0AAD8X8G8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_189928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357907.1">
        <property type="nucleotide sequence ID" value="XM_060501587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8G8"/>
    <dbReference type="GeneID" id="85385486"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="131" mass="14835" checksum="018B82B762E0D7AE" modified="2024-05-29" version="1">MPIIPELKLPEDASALGRYTTNPTAPFFITFTTSDHPDTGESWCPDVRAALPHIIAAFLPSSAPEMAFVEVGQRPEWRVPTNVFRTKWNVNNVPTIVRYELSDGEVKETGRLVEDEILDEKRLRELVRNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8P6</accession>
    <name>A0AAD8X8P6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calpain family cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_657290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358569.1">
        <property type="nucleotide sequence ID" value="XM_060510952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8P6"/>
    <dbReference type="GeneID" id="85394851"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF425">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="5">
        <location>
            <begin position="219"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="697"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="701"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="735"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="774"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="800"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="847"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1709435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="930" mass="103378" checksum="53C3E37354A01AB7" modified="2024-05-29" version="1">MATYGDPPPPVPPLPSATKRSKKSPQETLSDFWDKFHSKYPGKVTSIFPRALYTSLLPAFQEKGASSTRNAQESYDAAARECREKVKRIVRECERTNEKFTDPDFDIERDPKKNCLNGLIRDGDQGTGGSGAAGDVPYVSSWDVKNSLDTLNAAQILGPSSTIPIDPTAVSRFLGGDSDIWNPFANAAAGKGAKSGSGKVSKRHGVRGSEYYNPGSIHRVDWIFDSPQFTMNGYSSSDIKQGSNGDCWWLAAVATIAHRKDLMEKVCVARDEECGVYGFVFQRDGEWISTVIDDNLYLNESDFDYYGDVYDASGKKARQHRKRHQTGSDALYFARCDDQNETWLPLLEKAYAKVHGDYEAISGGWPGEGVEDMTGGVTSTIATNRVLRKDKLWKELVNSDGEFVFALAAMGTGWDWQKSGLALGHAYSILQSREEVDEDGKKVRLVQIRNPWGERSDGGVGEWNGPWSDGSKEWTPYWLKRMNHTFGDDGVFWMSYQDMLSTFMYIHRTRLFDDKWTVVQQWTSANVSWVTGFLQTKFVVEVKKSGMVVIVLTQLDDRYFHGFEGQYWFELHFVLQQATSTTSANSDESRNGEKKKTDAPEPEQICRVRPVHKWENRSVSCEVDLEPGIYEVLPKITAVRNSEGDVSTTKPVEEVVKEYAERNPQKLRQVGLQYDIAHAKGGVRNEDELVEKKKLEAKQKKESKKAKKRRKQKKALGIAAKALEDSAKVVSDLANEGKKTEEKKDSKDGVGKEGKKAEDKDQKREGDSIAIKIAVKESATETEKPANVNTSKPGDGPTPEPKKDDEKEPKEGKTEEKKPESDESEKKSEESKPAEETAITESKAEDVADEAPVDEAPAEEEEASDSDSDAESTVLDDEEELTGSPWNAVCVLGLRVYARDPEVSIKLVKPSDAEEASSLIVDGEAAGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X919</accession>
    <name>A0AAD8X919_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_641321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358597.1">
        <property type="nucleotide sequence ID" value="XM_060509549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X919"/>
    <dbReference type="GeneID" id="85393448"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1709463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="52" mass="5150" checksum="8EC5CD3CDAFB1407" modified="2024-05-29" version="1">MPGPIIPVSVITALSDPSKMCQCPATSPPSAATTCPKCQLPKAAVARASALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9W1</accession>
    <name>A0AAD8X9W1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_756593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359904.1">
        <property type="nucleotide sequence ID" value="XM_060514768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9W1"/>
    <dbReference type="GeneID" id="85398666"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="103"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1714088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="400" mass="42849" checksum="59F7CD860287A090" modified="2024-05-29" version="1" fragment="single">MQSSLSPEVPPPPGSTHSTHSNGSPNPLAMVPDSESPADRDSPNASSSATSDSRSQGQQPPVVAVPAACLACVSRPSMSAQVPRRRLSLLLIGSGGDGDGETGTTLFGRSKHLKCDGQNPCSRCLSSQSECVYVASRRGYKGPRRNNTANPNKRARSSSPTSTVGVGDNSCPMLLGANGTSVPTTMQNGMAFNTPGVVLPDTPSTTFAATPNFSNLQLYRSFGAAIGFNSTQLALGQSQPGVPAQVPVPTLAERYLDSFYHHFHASHPFALPKEWLLRIMRDTNMEPLLAALRWVGALFLDVGPARAGFLDEALRLVQDPTTRRDGFFVQALILLIVGLDGSCEQEKARNLLGDAERIALELGLNTREYATQYGRGIPVLEESWRRTWWDLFVVDGMVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA48</accession>
    <name>A0AAD8XA48_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_774248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000316">
        <property type="protein sequence ID" value="KAK1702254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357114.1">
        <property type="nucleotide sequence ID" value="XM_060515416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA48"/>
    <dbReference type="GeneID" id="85399314"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="132" mass="14697" checksum="F7B043F04A803789" modified="2024-05-29" version="1">MAATFHPFLCLAGKPRARIWELNRRASHRRGACSLSSTKLYQCRGDRAKSHMATAGALLVLAYPQPQPSCILVARAMDIPIHAPMLYIDWRRPFPSSLRHFIPGPTLRPRVARGRSAMSDSTSMMISSPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA94</accession>
    <name>A0AAD8XA94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_756632</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359887.1">
        <property type="nucleotide sequence ID" value="XM_060514774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA94"/>
    <dbReference type="GeneID" id="85398672"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098717">
        <property type="term" value="P:pantothenate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="37"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="472"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="504" mass="55671" checksum="DD2AB20A9CF4C553" modified="2024-05-29" version="1">MATENRSTGKKVKAFFLGNEATSKEERRLVQKIDFFILTYCCLSYFFNYLDRAAFANAYVAGLREALHMKGHDYNTVLSVTTAGMVVGQIPHGIIIGLQIVRPRIWLPSMCCLWAFLTMASAGVKNTAQLCVIRFFLGLAEASTYSGAIYIMGSWYKPEEISKRTAIFTASGQVGTMFAGVMMAAIYKGLGGLAGLGGWQWVFIIDGIITLPIAIFGFFYFPDIPENTSARYLSDSEKKIAVGRLPPVIKGSHGVNPFSLLKRLVLMPTFWVLVLWSPICATLEAWVVQGNFILWLKYHAESFTQSQINTYPLGVQAVGIVTNIMAAWHMDATGTRVPMVVLVCLIQIVCAAMLLVPNLPYAGTMFAFYASGSSYMVNPLIFGWASIILQRSGDEAVRSVTVYAMNIGATTLYTFWGIVFYAADEAPYWKKGAIVMIVCSVIVLCFMGLVIRIDRQSLAKYGSMTVEDFERAAAARETQTPPDGERSDENEDQKNTVSEKVTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAA9</accession>
    <name>A0AAD8XAA9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_683197</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358931.1">
        <property type="nucleotide sequence ID" value="XM_060511228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAA9"/>
    <dbReference type="GeneID" id="85395127"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="17"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1710871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="38229" checksum="E2B00E34055064C5" modified="2024-05-29" version="1">MATDYKFEGWVADDPSSVDGKMVWREYEPKVWEETDVDIKITHSGICGSDIHTLRAGWGATRFPAVVGHEIVGVAVRVGSQAEGGIKVGDIVGVGAQSDSCLSRDGPCDACEVGEENYCTKRVNTYNSLHRNGSQTQGGYALYHRCPGYFVIKIPKGIAPEQAAPMLCGGVTVFSPLKRYNVGRGKRVGVIGVGGLGHCAVLFAKALGADKVVAISRKSDKKQDATQLGATDFIATAEDEDWATKNARTLDVIISTVASPKMPLAQYLGLLSRGGTFVQVGAPEEPVPLSAFALIRTRVHLTGSVIGSPGEIREMFDLVAAKGVKVWVETRPMKEANQAVLDMVDGKPRYRYVLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAZ7</accession>
    <name>A0AAD8XAZ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_755568</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Cell membrane</location>
            <topology evidence="2 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361074.1">
        <property type="nucleotide sequence ID" value="XM_060514630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAZ7"/>
    <dbReference type="GeneID" id="85398528"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1718074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="60823" checksum="28E8EEF6983EADD0" modified="2024-05-29" version="1">MSQPYGESAGYYGGQQQQQQPPYDAKYTQQYNNGYQQDYNQQQNYQQGGYQQGYAPPPPPQQGFDNGSNGYGYNAPPQGYDPEKYTFEEAFKIEKPKWNDLWAAILFLAVFLGFAAVSGLTISGYSATKGLNGGGIYDGGNTFGLSTNTIVLFAFVLAVAIVLSYAYVWMARLFPKAFIWVTGILNIVFALVTAIYMLSRKYYSGGIVFLIFGVFLVFAFISWIPRIPFSALMLKTSIQVSKKYGHVYLVSFLGGMLGAAFAAWYSVTLVATYSKYQPSQNNPQCRSGQCSQGKVIGLIVFITFAMYWISEVLKNVIHVTISGVYGSWYFCVNNFPKGATRGALKRSLTYSFGSISFGSLIVAIINLLRHLCSVAQQQSAADGNIVSYVLFCILSCLISLLDWAVTFLNRYAFSHIALYGKAYIPAAKDTWKMIKDRGIDALVNECLIGPVLSFGATFIGYACAFLAYLYMVFTNPAYNQSGNYTPVVVAFSFLIGLQIANVFTTPISSGIDTIFVASAWDPQVLMRDHPQLYDEMVRVYPQVQQAIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBG9</accession>
    <name>A0AAD8XBG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_191192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357865.1">
        <property type="nucleotide sequence ID" value="XM_060501594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBG9"/>
    <dbReference type="GeneID" id="85385493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042230897" evidence="1">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="98" mass="10943" checksum="A9F1C515467F9FF2" modified="2024-05-29" version="1">MMPISFMMVILGGITISLATAIPKTSPPMREQDIFPCNCIFVVNKWNSVRADRIASYDCCYLAGGRWNSATCPLNYRNPQEVRRFSKCCEKNGGLGCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBT6</accession>
    <name>A0AAD8XBT6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_754834</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361944.1">
        <property type="nucleotide sequence ID" value="XM_060514537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBT6"/>
    <dbReference type="GeneID" id="85398435"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20346">
        <property type="entry name" value="BRcat_RBR_ANKIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20356">
        <property type="entry name" value="Rcat_RBR_HHARI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16625">
        <property type="entry name" value="RING-HC_RBR_HEL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1750:FF:000007">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000019">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045840">
        <property type="entry name" value="Ariadne"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048962">
        <property type="entry name" value="ARIH1-like_UBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19422">
        <property type="entry name" value="Ariadne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21235">
        <property type="entry name" value="UBA_ARI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="254"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1720433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="648" mass="73417" checksum="253D858794EFCD8A" modified="2024-05-29" version="1">MSDTIREHEVIGDNGTITFVRRPATPKPKKTPGSKLADPGTFGTIPPTTRKRKAAEATISSNNQDTTTKKRIASAAGQDAPPTPVTTASNGMDSEEDFMSAPSSDDEIMQDDSGEDMSGPDGMYTPLNPPRDFPASKPPTDVFDPSTDFDEDDFEDEPEDLGMIKDSDSKKKVAYDISFKVYEPKDIQRQQDDMIDEVNMILNIRKEDVAILLRHFRWNKERLIEDYMDAPNKVLEAAGLGSNVAGPPKLEAIPGFMCDICCEDEEGLQTFSLKCGHRYCVDCYRQYLTQKIREEGEAARIQCPAEGCGRIIDSKSLDLLVAADLNSRYHELLNRTYVEDKEILKWCPAPDCPNAVECAIKKKDLDRIVPTVACGCGHRFCFGCILTDHQPAPCELVKRWLKKCADDSETANWISANTKECPKCNSTIEKNGGCNHMTCRKCKHEFCWMCMGLWSEHGTSWYNCNRFEEKSGTDARDAQAKSRISLERYLHYYNRYANHEQSAKLDKDIYHKTEKKMVQLQTASGMSWIEVQYLNQASQTLQTCRQTLKWTYAFAFYLARNNLTEIFEDNQKDLEMAVEALSEMFEKPVQELCDKKLKVDIMDKTSYCKKRRIILLEDTADNLANGRWTFNVDLHGPSPVGATSSRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCM0</accession>
    <name>A0AAD8XCM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SacI homology domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_755291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361436.1">
        <property type="nucleotide sequence ID" value="XM_060514590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCM0"/>
    <dbReference type="GeneID" id="85398488"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034753">
        <property type="entry name" value="hSac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022158">
        <property type="entry name" value="Inositol_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF7">
        <property type="entry name" value="SACI DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G15890)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12456">
        <property type="entry name" value="hSac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51791">
        <property type="entry name" value="HSAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="256"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="HSac2" evidence="3">
        <location>
            <begin position="697"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="824"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="833"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1719352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="953" mass="106204" checksum="DB1C089B45C5608A" modified="2024-05-29" version="1">MPGIARKIIICAAVDGLIIQPFVTKGQRPAQPVRIKYGDASISPTPREQIPDLSQPNSSFEAFGVIGLITVSRLSYLITITRRQQVAQICGFPIYVVTEVAITPCASQQEAGEAIAKTALELQDRTTDKGANDSDSDDYTELPASGDEVEDPAQEAKADSDKDYETVKSTVAKDVIGRRGSYGRFAQTWFSKSGWTQDQKRSAGWSGAAHQVRRSVDHSPVKNAPPRPSVDDVNEPTTASTLLPKLLRMTQIFYGSSRSFFFSYDFDITRRWSSRSHAQSDDIPLYERVDPMFFWNKNTLKPFTEAGEDALLLPLMQGFISQKSFVVDSSPPQHDEGLGDSVELSTMRQPEAELSSPPPEAVRDSIDLRSTEKKFLLTVISRRSTQRAGLRYLRRGIDEQGYVANAVETEQILSSTSWDKSSKIYSFLQIRGSIPLFFTQSPVSLKPAPVIQHSPEANYAATKKHLERLKQEYGLLQIVNLVEKHGVEATVGTQYEKTVQRLNEEEAKGEDDVVGFEWFDFHSACKGMKFENVSQLLDTLRDKLEGFGSTVEEAGQITAKQHGVLRTNCMDCLDRTNVCQSSFGKFMLESQLRAEGYDLTAQVDQQTQWFNTLWADNGDAVSKQYASTAAMKGDYTRTKKRNLGGTLNDLGLSLTRYYNGMVNDYFSQAAIDFLLGNVNSMVFQEFEAEMMTKDPAVSMLKMREQAIELSQRRVISDESEEFMGGWVLFSPHQSDTLRAMPFEEVVLLLTDAALYLCRFDWNMDKVSSFERIDLAHVVGIKFGTYIISTVSPGQTDEMKNVGFVVSYQPGKNDVTRTNTRTFSNLGITKTKTDTTSSEQQQQKQQQQPQSALSSLLGGGRPKAPPVRKLAFKAPYSQSSAAVTGEEPKLSEIQQVVSICADIERLAFLSQPGKEKPGTESIIEKGEIISLEEARQSTGLLDHISYSLKRLVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDC9</accession>
    <name>A0AAD8XDC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Polyketide synthase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_720926</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363097.1">
        <property type="nucleotide sequence ID" value="XM_060512323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85396221"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF18">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="925"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2259"/>
            <end position="2339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="925"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1077"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="957"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2343" mass="253509" checksum="9D4FF0B1AFDC44B3" modified="2024-05-29" version="1">MGCRLPGEVDNPHALTQLLKRGGVAHNEPPESRFSLDGHHDGSKKPKTMRSPGGMFLENIDPREFDAGFFQVPRLDAVAMDPQQRQLLEVVYECLENSGVTLQELQGAQVGCFVGSYAVDYADMQARDPEDRAPSVTIGVGRAILSNRISHFLNIKGPSMTIDTACSGSLVALDVACRYLRTREMDGAIVAGCNLYLSPEHNMDVGPMKGASSLSGKCHTFDVKADGYIKGEAVNAVMVKRLSDAIRDGDPIRAVILGTATNSDGNTPGIASPSSEAQAAAIRSAYANAGITNFNDTTYLECHGTGTQAGDPTEVSGIASVFAPSRSPDQPLIIGSIKSNIGHSEPAAGISGLIKAILSLETGTIFGNPTFVTPNPKINFKGQKVFATRTGMPWPSGARKRASVNSFGYGGSNAHVVLESADQYLKDRQVLTHVSSHLTEEADLFDDDDDTSSMISVAKKPQLLVFSANSEFSLRGYVKLLRKHLLNPSVKADLRDLSFTLSSKRSAHFNRGFLLVDKAVIAEDSLVLGKKSPEAPKIGFVFTGQGAQWSQMGKALVDAFPTARDLLKHLDTVLKTALVPPTWSLLDELVEPRSPGLLRQPEFSQPLCTALQLAILSVLEDWGVAPHSVVGHSSGEIAAAYAAGYMSKEDAIKVAYYRGLAAKQLANVVDGTKNVGMLAVGLGAEAVMPFLEPYAGLVHIACFNSPSSVTLSGKVNKLEEVMAALVAESHFARLLQVNLAYHSPFMLEVSSLYEALLRQDFGACKKDRKHDSVRMFSSVSGKEMRHAADAAYWKSNMSSAVRFEQATKTMLADDSRPDFLVEIGPSGALSGPVAQVKKAVLGDGAEVQYIAAWSRGPAALKSLYEVAGKLFISGGEVNLANVNKTETWKPRTIIDLPNYSWDHSTHYWYESDASKDWRYRLFPHHDLLGSKILGTSWQAPSFKKSLKLADLPWLRDHKMGPEIVFPAAGFIAMAMEAIRQNTEALRSLEGKVLPTAYHYKLRDINFIRALVLDDSNEDTKIMLALHPRTGAKDSWHEFRISSQVGDAWLENCRGLVRIQESTPENSTAAEGTVKPLVDPVPGALWYKAMHDTGYNFGPVFQKHLEIESIIGSRESRSLVDLSPPASEHPQSWYPMHPAAIDGSFQSCAPSLWAGDRPGISAVLVPAIIDELAIFPVESISGKAISTTSSEYVGLGLPESTKSYKSNAVVLDSETGDLRFKLTGLRYHQLDTQEDPYSSHMYSRISWKPDVTFLTEETVAAIAAAEDPLNEFIDLAAHKFPNLSVLEASTIPSDASSVWLEGSKADTVVRSACRSFQFSSYDASAVVNAEETYGSKSGVAYAVLDVAADPKILQTPGNPFDLVIIRAADGSSESQDNMVRNARTLVSDGGHVVIQTIEADIPAISSSFGFCSSFSIASGDGSIIHILVASSEAVSKKQGIELIHFSDPTDLTAQVVSGLSKFGWQITDTRHPQGDHKTILVLSDLSAPVLPTITEAQWQLLKNTLVSGNQVLWVTSGSQLNVTSPDRAMIHGLGRTVRNEDPSISITTLDVESATGPKAVSAINDVLEHLGRAAHQRQTTGIENEFVERQGVIHISRVQPNEVVNVVEKALAHGAELVEGELHDFNTTVRLQCERVGTIDSLQYTEVAATELSVPDSSVEVELFAAGLNFKDVAVTMGIVPENQHLLGLEGAGEIRRAGKNAANIYKPGDRVLVFKKGAFGNRVIASVERTHHIPDWMSFEEASTLASVYLTALYSIFDLANTQAGHKVLIHSASGGLGIASIQICKFIGAEIYATVGTDEKVDFLVDSFGIPRENIFNSRTTTFAAQLKAATKGHGVDVILNSLTGDILDESWRCIADGGTMVELGKRDMLDRNYLSMEPFGRNASYRCFDMSHEHVSDTVIARLMRQMMSLISQRAIKPIAPMTTFPFEDVAGAFRYMRAAKHMGKIVLSAKDKADKPTVMVRPAIRRFDLPQTTSILIVGGLKGLCGSLAVYLAQQGAKHLVILARGGYDDERSQAVLKNIHAQGAKVDLVRGDVSILEDVRRAFKSSSVPVGGVIQGAMVLRDKIFTSMTTEEYHGAVACKVPGTWNLHNVAQEEGLDLSFFTMLSSVSGVVGQKGQANYAAANAFLDAFAVYRQKLGLSAVSIDLGAIDDVGYMHEHNDLRVALDRDAWTSINENLFRQIVRVSIQQQQRISSTGNSSQLITSIAVPQPDSSNLLADARFVSLAFGTGEVTSGGDGKDDKSRAVQALMLLLQSNADASVVLRAAVDVVNTQFQSTLRLSEPMEPAKPLSSYGLDSLSAVELRNWVRLDLGVELTTLEITSATSLTALCEKIVSKMKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE05</accession>
    <name>A0AAD8XE05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNARE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_382812</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363772.1">
        <property type="nucleotide sequence ID" value="XM_060502718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE05"/>
    <dbReference type="GeneID" id="85386617"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000021">
        <property type="entry name" value="SNARE complex subunit (Tlg2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="254"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1723717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="39461" checksum="C3220DC35EA25B31" modified="2024-05-29" version="1">MWRDRTNLYISYRQSYAHHPTKRTKYSGSAAGGNGFGDVFPGNTSYASGNDDTRGLLSAGAFEDDGDAVIEMDLLPPRWADISDEITDLLADIATRSQALERLHQKHVLPGFNDEDAKKAEERDIERLTQQITKGFHDCHGCIQRVEQMVRDSKHSGTITSAEETMAKNIQISLASRVQEASALFRKKQSAYLKKLRGMSGLGAGGVGVPGERGSTPQPSNSYLDPSMVESDADRSFSQSTLQATQQKLLQSNDAAIIQREREIEDIAQGIIELADIFRDLQNMVIDQGTMLDRIDYNVERMTTDVKGAEKELVIADTYQKKTTKRKIILLLLLIIAGMIILLVIKPKKRGGGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE38</accession>
    <name>A0AAD8XE38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_623077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364449.1">
        <property type="nucleotide sequence ID" value="XM_060508360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE38"/>
    <dbReference type="GeneID" id="85392259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="37464" checksum="D7036E1F8494F5B8" modified="2024-05-29" version="1">MSSSAPHARPPFSSLPLDPTGPPGNAWGLYGKDDRLGALNLLTPAVVAAAATSEIRTGQRVSLDWSLNNPSQPSFDRAPFESRLVTRAHPSGEKRTVNDDILHFNTQCSSQWDGFRHYGYQKAKRYYNNTTQDDLNNPENIGIDAWVEKGGIVGRGVLLDYASFCVRHSLPLDAFTSSDISLAHLQQIAAEQNITFRPGDILFIRSGFTAGYNAKDDAAQKAVAARASPDFLGLEPTKDVLRWIWETGFAAVAGDAPSFERAPIAGPHTAVGGVWKGEAWEEEMQGGGLLHQWLLGGWGLPIGEMFDLEALSSTCQELGRWTFFVSSVPLKVPGGVASPPNAVAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XED3</accession>
    <name>A0AAD8XED3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-aminobutyrate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_743202</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361703.1">
        <property type="nucleotide sequence ID" value="XM_060513132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XED3"/>
    <dbReference type="GeneID" id="85397030"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000029">
        <property type="entry name" value="4-aminobutyrate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004631">
        <property type="entry name" value="4NH2But_aminotransferase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00699">
        <property type="entry name" value="GABAtrns_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1720192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="477" mass="52504" checksum="FF001D609DBA6807" modified="2024-05-29" version="1">MRTFSATSSNRAAAIFSNEPSRPKLVTSSLPGPKVKDGLAELEEVFDTRSANTLVDYERSTGNYLVDADGNTFLDVFAQIASIPLGYNNPELNRASVSPAMVRAIASRPALGSFPSTDYADLLKTGILKAAPQGLNQVFTATTGSDANETAYKAACIWKGTRDRGGRDFSTAELESVMRNQTPGAKKYSIMSFSKGFHGRLFGSLSTTRSKPIHKLDVPAFDWPVAPFPQLKYPLDQFASENAAEERRCLEETERVLDEANDTVAAVVIEPVQAEGGDNHASPAFFRGLRELTKRKGVLMIVDEVQTGVGATGKFWAHEHWNLPSPPDMVTFSKKAQAAGFYFGDAGLRPDKPYRQFNTWMGDPVRALLFKAIYGEIEKHGLVERTARVGGYLYRELEALADKYPQHVLNLRGKDRGTFIAWDCPRREEVLALAKSKGVNMGGSGDAAVRLRPMLVFEKHHADIFLDVLEGVFKRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFX7</accession>
    <name>A0AAD8XFX7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">trans-L-3-hydroxyproline dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_718549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10320"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:39785"/>
            <dbReference type="ChEBI" id="CHEBI:57938"/>
            <dbReference type="EC" id="4.2.1.77"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the proline racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.77" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366399.1">
        <property type="nucleotide sequence ID" value="XM_060512089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFX7"/>
    <dbReference type="GeneID" id="85395987"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050346">
        <property type="term" value="F:trans-L-3-hydroxyproline dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442:SF1">
        <property type="entry name" value="TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="38342" checksum="B90A29EF306AC39C" modified="2024-05-29" version="1">MSFSEKNPFWVEAEDWHTAGEPFRIVDKLPQGYLPEAQTVADRRFAVIRTPGHPLDELRQSLCHEPRGHADMYGGFITPPDDSGAHFGVMFWHKDGFSTACGHGTIALGYWAITKGLVEAPKVDGVVDVVIDVPSGRVVASIGIKQGKPVYADFVNVLSYQLVEDLEVQIPSHHAAIKVNLAFAGAVYATLDASQVGVLVEPGSHQDFIRLGREIKASIGDKANYGTYDLYGVIFYNEEGEVDSERDEVKQRNVTVFADGQIDRSPCGSGTCARLAVLLAQGRITPGRSKLMHQSIVSTRFQADIISEETSPVEGFPACIPRVRGHANLVGRMNFYIDPSDPVYPGFLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG09</accession>
    <name>A0AAD8XG09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580819</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363458.1">
        <property type="nucleotide sequence ID" value="XM_060505387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF40">
        <property type="entry name" value="NORSOLORINIC ACID SYNTHASE STCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="1"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="905"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1274"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="905"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1068"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1352"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1362"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="938"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1698" mass="184279" checksum="E227F6672EA2259C" modified="2024-05-29" version="1">MDAFWDILHKGVDTHEMVPASRWNASAHVGDTSVKNVSGTGFGCWLHQAPQFDAAFFNMSPREAAQVDPAQRLALLTAAEALEKAGIVPNRTPSTQKHRVGVWFGATSNDWMETNSAQNIDTYFIPGGNRAFIPGRINYHFKFSGPSYTIDTACSSSLAALHLACNALWRGEVDTAIVGGTNVLTNPDMTAGLDRGHFLSRTGNCKTFDDDADGYCRGEAVVTIILKRLDDAQKDKDPIEACILGVATNHNAEAESITRPHAAAQKDLFEHILAETKVSSNDISYVEMHGTGTQAGDAGETTSVVTTLSPLTTRGTSVRPATSPLHIGAVKSNVGHGEAAAGVTSLAKVLMMMKHSTIPPHIGIKTKINHKLPDLQARNTHIATVATPWVRPVNDSRRVLLNNFSAAGGNTAIVLEDAPVFDNYTGPDPRRHHIVTLSAKTGESLVSNIGNLLQWLDGAAPREDPNLLAKLSYTTTARRMHHRYRVAVTATSIPQLKSSLQKELDARSGGEKILPAPAKTPGFVFTFTGQGSPHAGMGADLYARFASFRNNLQRYDHLCVQMGLPSILPLFEERDYFSRASLTALQLAHVSFQMALCKLWESFGITPKAVVGHSLGEYAALYAAGSLSQAGVLYLVGKRSQLMEEHLAQGTHAMLVVMAEEATVLAAIPGVVGRDLEVSCRNRKHNIVLGGTIAHVKEARTILESKGMRCHVLDTAHAFHTSQVDPILAQFRKIAKGIQIRRPAIPVISPTLSKVLREATDFSEGYFIEHCRKPVNIMQAASVAKAEGILDERTIAIEIGPAPVVAPMVKEVVASTMQTFASAHKTIDTWQLMTDAFSGMYAAGANVEWSRYHADFPECQQVLQLPSYGWTLKEYWMQYTNDWSLRKGDAPVIMGPANLAFSSIYNVVKNTLQPSADGEVVVDLDLNADDVHSMAQGHKVYGVPLCTPSVYADIAQMIGKYVKQITGMDVDAVGTEVAEMHIQSALVANDVGLKQVLRTEAKFDAAKKSLFCTFSTLDGKDKVMEQHANCSIRFTEIDDTKSQFAQAVSDAKIRAKAIQAQVGSDDSTFRFSKSMIYKMVGQLADFDPKYRGLSAITLSNNTYEAAGTVSFKGIPDNGKWFSNPAFLDSISQLAGFVMNANESVDLDKELFVNHGWESMKLFTHKLDANMTYHSYVKMTEGKDKLWSGDVIIFDQDQNLVGILGGVALQGVPKRLMDYIINSAMKKVSGGFSSAKSPPQVQQPQAIVTSDMKATFGDISLAEARAAPAAQQAAEDSWPVALKVLAEESGLDEKELADDVALADIGIDSLLSLVICGRLRDELDVDLPERALFEECLTVGDIRMRVSGTAISSAESSGHESDVTSVESDNASSVGSPDLDNLASPFSAAMTPINGLDTPGSYFEVIDMSAGDFKGKAVPSTPVVSTIPPAWSMYLQGSRTKAKETLFLFPDGCGVATSYLSLPTISPTTALVGFNSPFAKTPSRMYDHTLREVLQSYVAGLRQKQARGPYRLGGWSAGGILAYAVTQELVAAGEEVTSLTLIDSPPPNNGLDHLPDRFYDHCNKVGIFRNEMRRGAEQSEPPEWLMPHFRASTELLHDYHAPAMSPEAARNLHVNIIWAGECAFDGVRYPTLPPAMMEGEDCEGMKFLTEKRKNFGPGEWALLFPGASITTTVIEGEHHFSMMRGSGADRLVDSIRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG63</accession>
    <name>A0AAD8XG63_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366097.1">
        <property type="nucleotide sequence ID" value="XM_060510407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG63"/>
    <dbReference type="GeneID" id="85394306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="274" mass="31812" checksum="98D2CD0A880CB10C" modified="2024-05-29" version="1">MMPMLSMGGLPRSNSCKTHAKARLKETLTPDLLEKLRRFWFKHLKTDEAYILPQRSQMGRWFYSDVDFDEACVKKFRPVLEAMKSAKITTRDILTIVRPFTPLQWLGLVLLLDQVPRNVYRGPESSTVFKFFDPIAREIARHAINAGAATHNRIKYRVAYRMWFYLPFMHSEDLALHDFAVAQYQQMKHDFEELMAEDGEAGSDDQRKCWGVLAVQKETARDLLETNCDFETKHRDIIVQFGRYPHRNMAMGRESTAQESKYLETGGETFSAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGF9</accession>
    <name>A0AAD8XGF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_371665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363938.1">
        <property type="nucleotide sequence ID" value="XM_060502638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGF9"/>
    <dbReference type="GeneID" id="85386537"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="211" mass="23864" checksum="5BCA1AE3EEBA1004" modified="2024-05-29" version="1">MLHCRPMSLSRMDPKDALGYNLGPPRSRAPTDDAPFSSYQIRSCMRAKHQSFLSDPLPTVQLHTRQAGAIRPSGDPTSRPLVGQRGNRLWALGYAMSLLVQMVAQKSLIRRLVSHLAEPHLEKQAHYYRFGTPIRGEQFARLANDQPTKRCCPVPSRDVWITFVQIRGLGSLARCLMRGPRRPGMVYVKFFTRCAVRSRPMPGFCRPSESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGR0</accession>
    <name>A0AAD8XGR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_575918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365726.1">
        <property type="nucleotide sequence ID" value="XM_060504868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGR0"/>
    <dbReference type="GeneID" id="85388767"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005796">
        <property type="term" value="C:Golgi lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000093">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF5">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="3">
        <location>
            <begin position="175"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30802" checksum="D04F492603BB2733" modified="2024-05-29" version="1">MPSQRQLRTLLVGVLIGVVFVLFYTSSLRANEVKDERTIQDFYHKTVNGLKHKQPPGQAVLEGNKPKAAGHVPVDKDADGDVDADDEKLAKDMQGRLKAAEDKAKELANKKSPLKPDAPSDVVGKGNSAAGQKKKEKTANGKEVIESDEEEKKDESDEEHAVEVELNTILKKSPVIIFSKSYCPYSKKAKALLLEKYSIEPTPYVVELDKHPLGPQLQAFLGEKTGRKTVPNILVNSVSIGGGDDIIELDSQKKLVPRIIDLGQKKVEMKERSANSQKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHF7</accession>
    <name>A0AAD8XHF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_258260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366476.1">
        <property type="nucleotide sequence ID" value="XM_060501976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHF7"/>
    <dbReference type="GeneID" id="85385875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="26716" checksum="DB751FA581FB541A" modified="2024-05-29" version="1">MAAMTAQVHRPIRDADGEGGSVGGQRQDTGMVHALSLRLPRRQARSREETRENKSLLHTSTARSMWVAGRGGAYCTRYSSTRDVQTMYACHSDGRSEARQPALTTNQSIIELRGRIWGRTTAIRTPAAGTPAACIDFGEKTNHLLPSPRALPQSPGSYQCKRVARQAEDRSLDASPRGRRSFSNSRKFTVLPNTQRCGHGFRTGKSCSQGGDSIPPMPKCGRLLKSGVSGFFASSSVHHGEDRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIC2</accession>
    <name>A0AAD8XIC2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_612995</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367556.1">
        <property type="nucleotide sequence ID" value="XM_060507737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIC2"/>
    <dbReference type="GeneID" id="85391636"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034203">
        <property type="term" value="P:glycolipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117:SF5">
        <property type="entry name" value="PROTEIN RFT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="577" mass="62037" checksum="24A67BB849A703C9" modified="2024-05-29" version="1">MASSKEPASISPPVHTQTDASKTVVRGASLLIILQIGSRAVTFIANQLLLRFLTARLLGVSTQLEVYYLSVLFFARESLRVAVQRQETQGNAARQSSNSKKDDDPKVRIGRESQAVINLGYLAVLLGFFVTIGLGWLYLSSVDSSTAQTPNFLLALRLYALAAILELLSEPCFVLMQTRLRFGTRATAESIATFLRCTVTFATAFWASRAGVEFGVLPFAVGQLSYGAALLVVYLSSASRLALADGFSLLPKSLASTDSGGGEDYLASYFYRPTVSLASSMTAQSLVKHVLTQGDTFLVSVLSTPKSQGVYALASNYGGLLARLVLQPIEESSRSYFSRLLSSREVKTKSLPSAKDTAATTTASQHLHTLLKFYILLSSIIVSIGPVAAPPLLSLVAGQRWASEGAGDVLAVYCYYLPLLALNGVSESFVASVASEAQVHRQSAWMGAFSVAFGSAAFFFMRVMDLGAQGLVYANCINMLCRIVWSLAFTKSYFAGLETPFELFSLRPNAVTSIVCLSAPHLIRRFAGVASAGVSTSPFKDLIAIGLAAVPVVLLILFAERRFLLQCYNSARKPKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XID6</accession>
    <name>A0AAD8XID6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_749162</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368512.1">
        <property type="nucleotide sequence ID" value="XM_060513729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XID6"/>
    <dbReference type="GeneID" id="85397627"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021711">
        <property type="entry name" value="DUF3295"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053043">
        <property type="entry name" value="Ras-cAMP_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014:SF1">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11702">
        <property type="entry name" value="DUF3295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3295" evidence="3">
        <location>
            <begin position="111"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="61057" checksum="CE71F79AE4E759E3" modified="2024-05-29" version="1">MPYPLDTHVLTVDTNVINKVDTSNPQNLYSMWTVFAKCAESVEQGRRLENLSWRLWNRETFCCTEEEQASITATSLPREIPQASRIQDIPQLSGSVESENDDEAVDFTSFRGKERHITSGDFEKMVVSIIKENEPLSAPLPQMTSPYMPPMKETPDLAPASPVYEHSGSTTTESPCKSSEEEHSQEPTSPEITSRTTVVRGFSPSQIPRAIPASPKVISPAAIPEPRSSPAAKPILSKKQPMFSIGESCSSSEQGHSIENLRPIPAPVQKRKMFQVGGSSEEDSSLKSALASQPGSLLTGQKKTTSFADHVSTRMINDDNSAIADDSETDYVDESAIDDDDDSSDWEDSIEDSNKSSIDEKTFFQRVDSKVNLTSRRSLITLMMTEQNDRSSKLGNIASQSTSALPWSRTSHPAPPTLAVSPNDSDDAPLMMKRGNRSSPLKPINEVPRSAAQPIHATASHSHLQAALSPRTTRRNMLATELTESLRRNLLWERQQKSSTANAVLKRRHTSHDVANLKQYPEKVCLKNGDAPVNPQYFSKDTDNFGGYHSKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XII5</accession>
    <name>A0AAD8XII5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Formamidopyrimidine-DNA glycosylase N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_116817</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368707.1">
        <property type="nucleotide sequence ID" value="XM_060501125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XII5"/>
    <dbReference type="GeneID" id="85385024"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08972">
        <property type="entry name" value="PF_Nei_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000009">
        <property type="entry name" value="Formamidopyrimidine-DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="entry name" value="MutM-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="FPG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="H2TH_FPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22993:SF9">
        <property type="entry name" value="FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="N-terminal domain of MutM-like DNA repair proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase catalytic" evidence="11">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="317" mass="35526" checksum="7A4492390D81210A" modified="2024-05-29" version="1">MPEIAEVARCVHFLRLHLVGKKIAKVSAPDDANVFGKVGTSGPAFEKAVKGRKVVSVGSQGKYFWITFDKPPHAVMHLGMTGWIHIKGDKTAYTNYYKKMKEGEADIWPPKYWKFHIETEGTPKVSAAFTDPRRFGRIRLVDCPGAEIRSHSPLKENGPDPVVDVDVFTETYLRQKMQSRHVPVKALLLDQSHISGIGNWVADEVLYQSRLHPEQYCDTFDEGEMTRLYEAVRYVCQTAVDKLGDSDEFPDDWLFNYRWGKGSKGAASELPNGEKLAFITVGGRTSCYAPGRQKKTGQVVPSAKEESVEEEGDDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ6</accession>
    <name>A0AAD8XIZ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_620376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365350.1">
        <property type="nucleotide sequence ID" value="XM_060508191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ6"/>
    <dbReference type="GeneID" id="85392090"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="26806" checksum="238F09407F62FAC2" modified="2024-05-29" version="1">MDSETCREKGRLLTWSDDDSDSGDQPRRVSRRPGASCIITALAFSNLVLVALCVSLTLRLGGQPTPETTPHTVAASGPSWLPPQIPIKKTLNSEPIYGGLITNESEEAWDALMPHGRGFVIIKNETAVQEMPKFNATMSEYKGVISVFHQLHCVWATREAFFRLLRDGNSTEIDLGHLGHCWDFVRQAIQCRADTTIEWQVSDELSGSLGWGYQHQCYDYDALLAWAEEHRWGDEQSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJF8</accession>
    <name>A0AAD8XJF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_768679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368048.1">
        <property type="nucleotide sequence ID" value="XM_060515315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJF8"/>
    <dbReference type="GeneID" id="85399213"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="397" mass="44950" checksum="693DAF1934DB1D94" modified="2024-05-29" version="1">MSMSFFAVRDIKTHRHLRSRVSSGYSMTSIQSMEPLIQGVAISMWQRMGEFADRNAPVRMDEWANYFAFDVVGSLALGGPIGFIEKGKDVDGIIRSIHDGFWLMANMGNMPLQMTWFNNRIAQWALKSFGGQRLQAFSRFVDWLEVRVDERYRNGLGSKRRDMLQLFIDARDMSGQPVTKGDVMMEGVNILGAGADTTTVGILATLGSLLLHPEAIVRLQAEIDEAYCSLGLEKTGRDIEFLESSKLPFLSAVIKESTRLHPSIQYQLPRVVGPGGLQLDDVAVPEGTICGISPASMNRSMEIFGPDADEWKPERWIATDANHGEKIKYWNSHLTTFGMGSRSCVGKNLATVEMHNFIAQFFRRFDASLVDLDRPWQTKTQWFAFQRNFWVRVKRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJJ7</accession>
    <name>A0AAD8XJJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C2H2 finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366790.1">
        <property type="nucleotide sequence ID" value="XM_060504671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJJ7"/>
    <dbReference type="GeneID" id="85388570"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058925">
        <property type="entry name" value="zf-C2H2_AcuF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26082">
        <property type="entry name" value="zf-C2H2_AcuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="837"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="902"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1140" mass="125239" checksum="5F568AC62BE0C040" modified="2024-05-29" version="1">MASTYAVPPATFHDGQTSDTHNPSPPSSGQRRLTATSFDPNHLSPSSQLQSSSVSPNYNDTPAESISNYSQYHSSDFSDMDDGLDPFFGVDFSNTEAGTPSFLDPEHRTDSFGQATISQARSKNLDANTYPFTPEQTASLHTTSPRSDMRTIAKSVPERLPLSISPQELQRPFQPPQISTFAAQSTSQLTPDLSGSGRSSEDSAVPSPPMMAAQSPRVTVSMWGKDATEPVQSIERTFTPDDENSTTTHAGLSSAGDLISTQGPVADTTTPRRSSFSRRGLDPTNRPSTEVASVNDIMTRREIEEKNQEVDQWLSRSLNNDPAAASSQPETRLHASPDAMAGEDGIHLGNQTENRHQPGQTYFTARGGEMTATDFHIMNSNRVWGDSPVVHPISGPDTDRYQPESSQAAIARFNRMCMDNESIISKAATWGTRRRSLPSVIDMDTENVTSGNLLKKLSISRGEGGRRPSILKDLRGLVRRPSASHLLKRSRSTNGENIPKSEAAPPMEKRESLPHLLPTARTGSWGSKKTPTPSINTALVTMGSSVASIGTTHARNGSIGGTPITSPKSPFSSLQVKNTLRRPRSKSDLPKASGNDTHSNLVGMWRKTGGPPVAVLAKSNSTNVDLDEDDDDEDDLYEDGDMNAESSKLIQDVSANFAGFQTHVLRLNPDLATNNNYLVDRIAHQQVVRYKSLLSAKVKHLGIGQACTCGSFCLARGGRPVLLDQKGDSRDIDPLSTGADSGDGDSTPVEGAITKDSFPQDIPMPPTQSLPAEFECQLCFTLKKPKKPSDWTKHVHEDVQPFTCTWDRCRDPKIFKRKADWVRHENEGHRHLEWWTCDVEDCRHTCYRRDNFLQHLVREHKFVEPKNKTKAAIKRAGGVDPTWQKVEQCRHETTKRPQEEPCRFCGKQFPTWKKLTVHLAKHMEHLSLPILHLVAAKELEPDTIISPVQDPPPRAPFNAPTPLDESVVKSEHSLHNYGNQSSYQPHAMMANNNGLYQNVNSLGFSGVAGNSQFPDYMYSSQYPNNGQPMAQNLMGVQPVNRATQGFNHQYQNTNNVAIPTASYMGGQQQYMSLAQDTEPFPALDHNALGLHQPGQMGVGMAYDGLMGQSNIDENQYNSQGSISPYSHSPLQGGQGFYPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKJ6</accession>
    <name>A0AAD8XKJ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5B</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_569233</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060504166.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="85388065"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="eukaryotic translation initiation factor 5B"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Small_GTP-bd"/>
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    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
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    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003078">
        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="471"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="205"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="296"/>
            <end position="353"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="366"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="444"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1729081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117244" checksum="AE5B0A163173F0D7" modified="2024-05-29" version="1">MPPKKKGNKARANDDWENELGETIAPAAAAPEADAEKPAEGEPEEEVSGLMATLRKNREKRKKKGIEEPVAEPEQEDAPSPSLAEKAPQEATMDDEFALPEKKGKGGKGKQAQAAAPADDDENSGRVLTKAEKEKLKKEREKQRKKENAAKKKPATTKAEPAKAAAPEKKDSPTPAAAAVAPPPAEEKGGKKKKIPAALAALQKQQEELRRRQQEDAEFAEQEKKRIEEEERAAEEENKRKEEAKALKKQKEKEKIEQLKKEGKFMTKAQKEEKARNERKLQQMLAAGIKVGPSEEAEKKKTVYDNKKKGGRKAQDKVDEEKALAEAAERAKKEAERLIKEAEEKAAKEKADAEAAAAAKKKAAESDLEDDWEAAAASDEDDVKDSWDADSDEEAEKKKAAANGKADKKDEEANSEDDDEDDDSDSESESDSEDEKETAARQAELQRKKEAAERREKAHQAALAARSKDNLRSPICCILGHVDTGKTKLLDKIRQTNVQEGEAGGITQQIGATYFPVEAIKAKTAVVNPDGAFDFKVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGLEPQTLESMRMLRDRKTPFVVALNKIDRLYGWKKVDNNGFQESLALQPKGVQNEFKNRLEQTKVAFAEQGFNAELFYENKSMARNVSLIPTSAHTGEGIPDMLKLIVQLTQERMVGALMYLSEVQATVLEVKAIEGFGMTVDVVLSNGILREGDRIVLCGVEGAITTNIRALLTPAPMRELRLKSAYVHNKEVKAALGVKISAPGLEGAIAGSRMMVVGPDDDEDDIIDEVESDLATLFSRVEKTGRGVSVQASTLGSLEALLDFLKDCKIPVANVGIGPVYKRDVMQAGIMLEKAADYAVMLCFDVKVDKEAQQYADDVGVKIFTADIIYHLFDAFTKHMAELLEKKKEESKMLAVFPCVLNTVAVFNKTGPIVVGVDVVDGQLKINTPIAAVKTNAVTGVKEIVNLGRVSTSIERDHKQIPVCKKGQPSVAVKIEMGGHQPTYGRHLEESDVLYSLISRASINTLKEFYRKDVSNDEWQLIIKLKPLFDIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKS5</accession>
    <name>A0AAD8XKS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_727575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369267.1">
        <property type="nucleotide sequence ID" value="XM_060512787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKS5"/>
    <dbReference type="GeneID" id="85396685"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="79"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="656" mass="75029" checksum="D538E45A315C7967" modified="2024-05-29" version="1">MYDSVQADIDEWLKEIEKMAEIAQRQATMLSFLALSPRSFTDKAKLPCYVLPTASTNRFFNRDEVIEEMDRQLGGQRIDGLRSIALYGMGGVGKSHVALKYIEKKKAEKGLTAIFWVHAENIISFQQSFTDIALKLDLPGAQRTLHDENRLIVRDWLSQTVYDNVESFDLLRANWPLPGSHGLALITTRNHSLAFDPASGGLEVPSWNTENGTKFLLHLLSGHISADLLANEAKSAYSLSERLSGHALAISNMSGLIQRRSWSISQLLDNYGSNLNFKDGLEAVWKVSFENLKPDSAALLAAFSYCAPDSIPHSLFELKEAEDLPDSLLWFLDVDRFLLEQQTWPELEDLVEVGKLALATLPEQDPELYNLTSPDTYIAQMWARRGHYRLAIEVMVSARNMKLKAPQEDHQNLSWMANNISAFYSCLGEYKTALEWQETSRVSWERWAKSENVDFHWHPNQRYGQGRTLAYMKRYDEARTDIDESLEDMMTTKPVIWGTAGPCQFARARLAMFEGDFKLAELLFQRAQSIWLTGNSSRTSDFYAATIYRMGCCALLEGEVERAMKYLQDAMAITSLRKDIQVGEHARCLYKLSEALYQISGRELEADRLLKEAEELYWKRVEKPKGVSEEDHAEYEVPQIHPQEEDYDSLVYMLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKT2</accession>
    <name>A0AAD8XKT2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP synthase regulation protein NCA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_607059</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369247.1">
        <property type="nucleotide sequence ID" value="XM_060507407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKT2"/>
    <dbReference type="GeneID" id="85391306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="669" mass="75364" checksum="651FBC4703BD0421" modified="2024-05-29" version="1">MSVVADQVRRLDAQLDRIPLGLSLSQEDGELSAEEHGIFHSATVDALSSPRIEELLHIVRALSTTSTSSSLLPAQRIRSLLQESKLAEWDFQAEQDDEARRGPYQSEIEWLLVSKATVQTYGIILNTLLDQIIPLSDEMWYWDEVLSSYTYSSLYTVQTSPLRLWSLTKDVYHESKHRIRNLSQTPGDIVASTRTGLSQQWKQFYGIVRDSIRDSSITTLQRKVLSPVALSRGEARRKLAHLRRLRDMIASGLGVLVDEGLTFGGDEDDDKSEAGVNSHDWKGVVERSVALMDMVLKEALTLESGVNDFEDKVFAGVEEDPELSIHIEDANALEKPSVLARRLLNLLDNGLPNHVMSAQLLVRENGRPSRFIRYWLPATAALLSSTTVLRLLANRRAEIISWIRDIGSTVRDFWFNWVIEPTRKIVGTIRHDSSSEIAIMSRDSLKADRESLERMVVDFALDKPHFAGDGSSLTDAQIEIIRTKVSEGDVTPVLRAYEKDLRTPFVGAVKGDLVRSLLIQVQKTKVDLEVAISGIDSLLKSQELVFGFVGLTPGVLVSIGIVQYLRGIFGARKGARQSRKTGQSIRVLRNIDRIFSEATPSQNNLLSYKDHGLLLCEVHVLRNLMQRALPRDRQREFLEDLDDLANLKGIQVQVRALDRIRWAYAKWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKW3</accession>
    <name>A0AAD8XKW3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor MEX67</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_568702</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the export of mRNA from the nucleus to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369292.1">
        <property type="nucleotide sequence ID" value="XM_060504108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKW3"/>
    <dbReference type="GeneID" id="85388007"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042272">
        <property type="term" value="C:nuclear RNA export factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14342">
        <property type="entry name" value="UBA_TAP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000013">
        <property type="entry name" value="mRNA export factor mex67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000018">
        <property type="entry name" value="Nuclear RNA export factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="11">
        <location>
            <begin position="359"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="12">
        <location>
            <begin position="557"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00069694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="610" mass="67223" checksum="4F8F500273701038" modified="2024-05-29" version="1">MGSGAGASNTRRSNNLNRGPSDDSNNSRPQRSARSNGPPTKSGSKVHQAIARHLDTGDGNDLVSRRKGQGPGLVWLSVKGLKESKAASNNDGGLRDLIMFLERKATTLSGRNKTVHIKKSSLKGDLVSVAASKEDAEEILKVNTFTFAGTQLEITDSDGSMAKANEASAAAQETKQKLQGIMSLRYDMENKLLRLDALNQDEGLIQMGMLESKDRAEKLFKVMMRICDELFKTAQEKIDAIHSISLANNNIDTVAQVEEMADTFPDLKNLDLSGNQIDNIAGLSRWRSKLKKLETLYLTGNPIPIADPKVVLELLHFFPKLQVLNGEQLTPERIAELKAAGRPKPIPQRGPDFRDANGIGEAFLLEFFLGFDTDRTALLTKYYDDNSQFSLAVDTRAIRDESQPQPMPWSSYIKQSRNLMKITTPAARAARLITGREAIWNLWNDLPKTQHPDIKSDISKYIMDCHLLPGLADPSGQTQSGVDGMIISVHGQFEECDKAGKTGLRSFSRTFVLGPGRPNTNPIRVISDMLSLRAFNPLPNVFVAEAQAPAPSAQEQEQRQAMIVELSKQTTMTPTYSEMCLSDVAWDFTRALAVFHEKKSQLPPDAFASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLC7</accession>
    <name>A0AAD8XLC7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_727228</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369578.1">
        <property type="nucleotide sequence ID" value="XM_060512778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLC7"/>
    <dbReference type="GeneID" id="85396676"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="264"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="39845" checksum="31B8BF4C482B917D" modified="2024-05-29" version="1">MAPMLEFRTQGYNPYAVKYSPYYDSRIAVASSANFGIVGNGRVFCLGLTARGIEVETTFDTNDSQYDLAWSEINENQLVVACGDGSIKLFDLGVKDFPVMNFHEHKRETFSVNWSPITKDTFVSSSWDGTIKVNQTTKISCEGTDNTRNQWSPTRDHSLRTLPVGNCTYSASFQPSNPHIISSVSSDSQIRIFDLRTPVSSRYHLTSMIPVHAAGPSFPSAAPGEVLTHDWNKYRDTVIATGGVDRAVRTFDIRNPTAGPTAVMQGHEYAVRRLAWSPHASDLLLTASYDMTVRLWDDRSNAPPAGPAGGAQIGAQVGVMNRHTEFVVGVDWCLFGVGGWVATVGWDERVLLWDANALLGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLK3</accession>
    <name>A0AAD8XLK3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_716148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369698.1">
        <property type="nucleotide sequence ID" value="XM_060511822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLK3"/>
    <dbReference type="GeneID" id="85395720"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="73"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="406" mass="45674" checksum="5450EEAE2ACE181D" modified="2024-05-29" version="1">MPESKLEQAVQPRPPQSSFRLAERVCQLVLVFSISFAAMFMMMTKISPGKWPLTEPSISKPRLKVSGQRDYLIAIFSDLHYGEQEFGWGIDQDKNSTRVMQSVMKSEQPDLIVFNGDLITGEDTHKENSTLYIDQIVAPLVKTNQRWASVYGNHDSKHTLDREQLFRAEKGYDLCYTTSMGDNLPGITNYYVPVYEGDSKDPILLLWFFDSRGGTSYQTDSDNMDDIPNWVAPETAEWFTKTYDDLKDKHGRVIPSVAFVHIPPHIFLTAQQTNLDPAKFPGLNADSPLAIQGEGGEDAPFVEALLEAEGLHSIYVGHDHGDSWCSTWPGHEAGLGAEAPFLCFAKHTGYGGYGTWERGARMIKLSFTQGDDPDMSVESWVRMENEEIITRVTLNETYGQDTYNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMB3</accession>
    <name>A0AAD8XMB3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_567035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370088.1">
        <property type="nucleotide sequence ID" value="XM_060503916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMB3"/>
    <dbReference type="GeneID" id="85387815"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="30"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="21288" checksum="9207D3AB8AC512FB" modified="2024-05-29" version="1">MQLLRHTARTAFRGRNTNLTNGVRMPPPKQFISAAAAHFSTSRTSPAKNQIYASVRRPDDFHTYQLLSSSSRTPLITLWTTSWCGTCRVVAPLIQSIVESGVGEAEGGVGYCTVEFDSPDVMSGGLGMTYMITSIPTLLSFDNQEAQIQTKVHDAKKLTDRAFLEEWIRSEARRHGQRGGGGGSGGVFGGLFGGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMG2</accession>
    <name>A0AAD8XMG2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370121.1">
        <property type="nucleotide sequence ID" value="XM_060513488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMG2"/>
    <dbReference type="GeneID" id="85397386"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="32264" checksum="D2E4D9C8BD10C021" modified="2024-05-29" version="1">MVPRSEASANSLKEDNRWCLRCLGFYTGVYPSKNKPVANYYCRRNLVKCARCAEPGKDKRCLMIQKEQWPQTLEIIEKTRQIILAEQADGESEKFARDRKAVKDLYRHVERVTRAYHNTQLQDDQQSAVSDEDTPLAYNTASDDEEMGEIQCAQSFAGPSRSGRSPNTAGLSRISKFLVDIRRLEEEKAEASRRLGRAVWIAARDPQAIGPSDQLVRLVVDELHRDARQGDARHGIIDAFRFVDNAHEAREEAFRRLGDLALAIMPASSTPEGTGSSGSGRAPNSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNJ2</accession>
    <name>A0AAD8XNJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA wybutosine-synthesizing protein 2</fullName>
            <shortName evidence="2">tRNA-yW-synthesizing protein 2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_374861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370618.1">
        <property type="nucleotide sequence ID" value="XM_060502674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNJ2"/>
    <dbReference type="GeneID" id="85386573"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026274">
        <property type="entry name" value="tRNA_wybutosine_synth_prot_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038972">
        <property type="entry name" value="Trm12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="4">
        <location>
            <begin position="100"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR038972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="47308" checksum="D5FA6B708F25E5C8" modified="2024-05-29" version="1">MMTDRREKPRRKKPKPENPISAATRAWLISLPSQTQPWQSQDELEILLNQHTPKRFTVYEPMLLLPSGSFNKGSWPSILNHQDIREDEIHRLWEAILRDVSKTGSTTLTHLAVNEGIPLQKDTDSESLAVEESENILRTPSGLKILHGDFGPSNNPANPSPQDFEGAFWVSTKQNGIHQTWAPRWTMFSRGNIKEKTRLLDFHSQAGPDTTFPRHQEPASALKNYWAVDMYAGIGYFTFSYAKLGLKLLCWELNPWSVEALRRGAVANGWRVKVIQGKDLPLPAAQLLTGDEQITIFLQDNQQAGLRIADMRALGTVVDILHVNGGLLPTSEPTWRPSWDITAPCENDCWLHLHENVGVHEIEARRAQIQRLYDGWAETTNGRGRAATVEHVELVKTYAPDVWHCVFDVHITRSSSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNQ3</accession>
    <name>A0AAD8XNQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_565863</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370766.1">
        <property type="nucleotide sequence ID" value="XM_060503808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNQ3"/>
    <dbReference type="GeneID" id="85387707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000048">
        <property type="entry name" value="DnaJ family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="139"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="139"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="45675" checksum="BC03A397580E7BC0" modified="2024-05-29" version="1">MVKETKLYETLGVAPTATEQELKKAYKTNALKYHPDKNAHNPDAEEKFKEISHAYEILSDSQKRTVYDQYGEAGLEGGAGGGGGMAAEDLFAQFFGSGGGFGGGLGGMFGGGGMPNRGPPKARTIHHTHKVSLEDVYRGKISKLALQRSVICSKCEGRGGKEGAVKRCAGCDGHGMKTMMRQMGPMIQRFQTVCPDCNGEGETIKDKDRCKQCNGKKTIVDRKVLHVHVDRGVRSGTKVEFRGEGDQAPGIQAGDVVFEIEQKPHNRFTRKEDDLLYQCEIELVTALAGGTIYIEHLDDRWLSIEILPGEAIAPDAVKMVRGQGMPSPRHHDFGNLYIQFNVKFPEKGWTEDPAAFEALQKLLPAPSLQTVPPPEAMTEPADLEDLDNSSQARVFGGAGGMDEDDEDGHPGAERVQCASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPP3</accession>
    <name>A0AAD8XPP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Plasma membrane proteolipid 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_565593</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371199.1">
        <property type="nucleotide sequence ID" value="XM_060503773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPP3"/>
    <dbReference type="GeneID" id="85387672"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF116">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1731144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="57" mass="6265" checksum="F7C85D01ECC692A3" modified="2024-05-29" version="1">MPFTASDICKIILAVILPPVGVFLERGCGADFFINILLTILGYLPGIIHALYIILKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPU7</accession>
    <name>A0AAD8XPU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450 3A13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_565331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371287.1">
        <property type="nucleotide sequence ID" value="XM_060503742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPU7"/>
    <dbReference type="GeneID" id="85387641"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11059">
        <property type="entry name" value="CYP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF164">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="484" mass="54803" checksum="8C744533F9129F31" modified="2024-05-29" version="1">MLLLSPVFLGAAFSVLALAYLIRCFLSPLWKVPGPRTSAFTSLLLKWHELQATRTKYIHALHRQYGPVVRIAPNEVSFTSYEAVKEIYCSGGSGYDKTEFYDLFKVYGRRTMFTTLNKEDHAKRKRIIADRYANSNVLRPVPLGGIQERSQKFINLCEKSVGMSHDIFMSLHSYACDCVTHHLFHPYGSNCLEDDADEEMMHQVAADDSLQNRLLQHYSPALHKLLSRFLYFFAKPRETPLADTFVIESSKKPDPAAFTLLSRLHEKAGQGLDQLDMAGECLDHMAAGIDTTGDGLCFLMWELSQPRSLRFQETLRRELRENPGAAFDTLPFLDAIVQEGLRCFPAIPMSLPRYVPQGGRVIDGYAIPEKTTVSCQAYSIHRINEEVFPEPDLFNPDRWMEPTGDAERKRLMFAFANGGRGCVGKHLALAEMKTLLTDIYTRYTTLPETSMTEESMAMSDQLISSRPLGQKCLLQFVPAGEKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQA9</accession>
    <name>A0AAD8XQA9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent RNA helicase SUB2</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-dependent RNA helicase sub2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDZ83DRAFT_646116</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371678.1">
        <property type="nucleotide sequence ID" value="XM_060509924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQA9"/>
    <dbReference type="GeneID" id="85393823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000168">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase 56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="80"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="267"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="18">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00040177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00040402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1731623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="433" mass="48909" checksum="D51FABAA8C3BF032" modified="2024-05-29" version="1">MSAEEDLIDYSDEELQTNETAAASNGKKADAAAGNAVDKKGSYVGIHSTGFRDFLLKPELLRAIGDCGFEHPSEVQQTCIPQALLGGDIICQAKSGLGKTAVFVLTTLQQVEPVQGEVSVLVMCHTRELAFQIRNEYNRFSKYMPDIKTGVFYGGTPIQKDVETIKNKETCPHVIVGTPGRLNALVRDKVLRLGSVRIFVLDECDKMLDQIDMRRDVQEIFRATPTQKQVMMFSATLSDDIKPICRKFMQNPTEHYVDEDTKLTLHGLQQYYIKLEEREKNRKLNELLDDLQFNQVIIFVKSTLRATELDKLLRECNFPSIAVHSGVSQEERIRRYKEFKEFNKRICVATDVFGRGIDIERINLAINYDLPADADSYLHRVGRAGRFGTKGLAISFVSTDQDQEVLKSIEKRFEVALPEFPKEGIDASTYMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYK3</accession>
    <name>A0AAD9CYK3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_608262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368867.1">
        <property type="nucleotide sequence ID" value="XM_060507468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYK3"/>
    <dbReference type="GeneID" id="85391367"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="114" mass="12438" checksum="7AA32D5A8C003E82" modified="2024-05-29" version="1">MKEASTDDSSSNDDDSSTGSSNGDPFHLNKYLTPEYQAKAQDYLKAFDEAQAQAQAQATDKPVYGPAPPPFWTQSGGKTIAAKPTATDNRSQKTAESDESYTFIQRDPKEVHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYP6</accession>
    <name>A0AAD9CYP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_85559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368927.1">
        <property type="nucleotide sequence ID" value="XM_060515956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYP6"/>
    <dbReference type="GeneID" id="85399854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="15486" checksum="4F8DB95BE4C6EC48" modified="2024-05-29" version="1">MLVKGAAAASASSGEPRPRISTAVSHAAGPPTSKISTPPPARQPVGLFSEVAFSPPPPPGRDPLFTATVGVAARHAIPDLAAAPMQDGGCLYTNVAECQPCDKDTCGKILLYQDIVSKKGGALLAGTSLTTQYPPLGSEKKNGCSTVHSYVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZL9</accession>
    <name>A0AAD9CZL9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_86477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368960.1">
        <property type="nucleotide sequence ID" value="XM_060515965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZL9"/>
    <dbReference type="GeneID" id="85399863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="577" mass="65006" checksum="525106241AC45A06" modified="2024-05-29" version="1">MSEYYSQERVDMVAILATSQRIEFERCLAEIKGRNGGNRSDTMGVLQRLASEAEVASSILLSLQAENIEGSYVTIHRMLAQQTLLIKTQLLEVAGEMGKPFLPTPMSNPRLAQQSMIQQQQQQPQQEEEADWEHQKPPSPLPRPPRQPKVTLHFDQFPIFRRLSNTTPTLDAMDRSEPPEKQKSPIREIKGFPPRNIRKRRQTNNSSPSHLLQVPAESGKKDNEPTGPRRANQGGSVRRRDQASVSPSPPRKATLWPIASNKFSLPALVNISLDVNEERDPLRGRKPGDVREAWINDLDSRTDSKDEGEAKMEVEMGDGRKTGDQGEGGETRGRKRSADKDLYPSTVKKPRSEPRGGKNGGSPGRIKSRDAEPTAAVPSIPDSPKPVGCCIFAEALNPRYLFGTEKEDQRALHYRDAIEDLIQLVGDTPHAITSDDPLMREYHTRQFKDIQTVLRRIPSKAISKKMIDEKLLAIRQEETAIQKGQIPHLRGIKAKEARAKRRQQLMQEKEVLHRRLRACNELNDKIFAFGAEGAAIFADWIVEMKLRVDGELEFAERALMMPYSGGVQEDGREFCCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZX4</accession>
    <name>A0AAD9CZX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_727266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369633.1">
        <property type="nucleotide sequence ID" value="XM_060512779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZX4"/>
    <dbReference type="GeneID" id="85396677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="161" mass="17430" checksum="7BABC156DE43FF54" modified="2024-05-29" version="1">MALEASQAALAASNSQMSASEIANLTEKFKIGTAEEIPIIEEQGGIALTSEEIVAQDILSVVRAGMLEEEVIGAEAIAAVRGLARAGIYGLIAAVVVFGMSIPIPSALVQYADVILDRPWNSFPVSGRTHRLRSSRQSLKRLRLLGSTFKSKKRLQWRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Q5</accession>
    <name>A0AAD9D0Q5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_647536</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370037.1">
        <property type="nucleotide sequence ID" value="XM_060510092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Q5"/>
    <dbReference type="GeneID" id="85393991"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="18757" checksum="E6B52A42AD02724C" modified="2024-05-29" version="1">MAFPGGGAMPPQESQGGSPGAAASLGPPDPEMKAMTNFMENCFTKSIMSGVMGFGMGGLFGMFMASMSYDTPFHTATTAGQTTVTPIADLPLRQQLRVGFKDMGTRSYSMAKNFGKVGALFAGIECGIEGLRAKNDLGNGVAAGCLTGGILAKNAGPQAALGGCVAFAAFSAAIDAYMRQPSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1A4</accession>
    <name>A0AAD9D1A4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_716158</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369711.1">
        <property type="nucleotide sequence ID" value="XM_060511825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1A4"/>
    <dbReference type="GeneID" id="85395723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071021">
        <property type="term" value="C:U2-type post-spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.940.10:FF:000008">
        <property type="entry name" value="Related to potassium channel regulatory factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="9">
        <location>
            <begin position="131"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="49"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="353" mass="40397" checksum="55E961A6B95DF51B" modified="2024-05-29" version="1">MDFAALMSKELDKSKKPTSTAAAASSSSKYIKRADVEAKRREEYLAEQARVEAEREAKAAAKRKREEDDAAENKIREEKRQKLAEESRRRREEKEAEEERARRKRLGLPELVKATAEDDDDAAVEEGMEDIPDGQLAEKLRALGEPATLFGEGHGARLRRYRRLTTVVTKGPIPTTLQLVEEKDMKVDAAVPKDKEGRRWLFRQLASYFTMVLAEYEKAMEAERRDTTASKTAYSAMVQSRENLKPLFRKFEKYDLDDDLLAPIIEIVKAAQERRYVDANDGYLRLSIGKAAWPIGVTMVGIHERSAREKLHDGERGHVMGDEVTRKYLQSIKRLLTFAQVRWPPTDVRQLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1F2</accession>
    <name>A0AAD9D1F2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_602809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370069.1">
        <property type="nucleotide sequence ID" value="XM_060507193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1F2"/>
    <dbReference type="GeneID" id="85391092"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="338" mass="37970" checksum="8105BB364A18ACBF" modified="2024-05-29" version="1">MEQEAEHQPIEADDSGIDDASSVGGLSADESSASLRSSILDYRRENGRTYHRMSDGKYAFPNDAREQDRLDMVNHIWMLILDNAFCLCPKNDGSTAKRILDLGTGTGVWALDYAETFPEATVLGVDLSPIQPGFVPPNCSFEVDDLEKEWTWSKPFDFILGRNMNASFSDWDNVIKQAYDHLEPGGYFEIQDSCWPPVSDDGTLRKDSALAKWSGLLVDACNKINRPVDKTLELPGKMEAAGFEEVVVTPVKFPSSNWPKDKKLKDIGEWNRSMLMGGLEGMTLGLLTRFMEWSKEETLVFCAQVRKDLLDTSIHAYWNGYVIYGRKPLIATEEVDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2A9</accession>
    <name>A0AAD9D2A9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_726651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370476.1">
        <property type="nucleotide sequence ID" value="XM_060512765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2A9"/>
    <dbReference type="GeneID" id="85396663"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="679" mass="75229" checksum="619376C788406185" modified="2024-05-29" version="1">MPRPTTDRVIHDYTAKILPATMILTLVIFTVVVLVYSISEKAAVPRDAAVAFAGIVFGFSGLWLLGHLVMYCRGAQAVSPPPLALPLPLAGIATGVGATTMVVPQVSQAAVDVVVPPTVHLHQQQQQQQQQHQRVYQPQNNQYREYEQPQGFPPQLQPHSQPEDQSHRQQREDAVVVRADQREQQHREQQQHEGQQRGQQAEAQGPMQSKQEEQRKHESHRRLTDHKPYVKEPPYPESPPGAYQGGPLEETKKLSQQRIDQHRQQQLEQQPQQRREISGPLENVWQKRPGVPVSQPAPVTVPGPVQPRQQPKGPRTMVGKAPEPPERVSSLQKSLPGTSSRRHRSSSLSSSRVKRPGQLSRGASSLPRPVRGGRFGDASEAIGERGRSRVDRNRPERYQDSEPQPRSASIKSTSLDSATRASLKPAPLNIAKGDRSPPGDERSIEESRATGNHACLPSRRSDQLESDPLSRRALGQTVAKNRVPTIRKVPPTPPNEPAIPVQPAQGEVRDQSIRAEASSSSSLWRSPPPSPAQSARSSKTFDEMGILPGRESTVYEDIRHSMSDFGNLLCRSFTNPRASDSDSRGKPRSLMTDFQTSVVFMPNYNFTAAQLLDPESHEYGSLPFLGQCERDEEKVAAGEELEDRGDVAMVCSSDNAGQWLIKLVELAESSNEVEGDFMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D347</accession>
    <name>A0AAD9D347_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exosome complex component RRP45</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribosomal RNA-processing protein 45</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_564932</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371360.1">
        <property type="nucleotide sequence ID" value="XM_060503695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D347"/>
    <dbReference type="GeneID" id="85387594"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000005">
        <property type="entry name" value="Exosome complex component RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0271">Exosome</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="191"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="32837" checksum="8C864FFE6EF0845F" modified="2024-05-29" version="1">MPREAEPSANEKAFVTQALKENLRLDGREFDQYRKVQLTFGDEYGVANVELGKTRVLVKVSAEVTVPYPDRPFEGVFQITTELSPMASPAFEVNRPTEAEVLLSRLLEKTVRRSGALDTESLCLVAGKKVWSVRADVHVLSHDGNLTDAACLAVVAALRHFRKPDTSNEGESLTIFTPAEREPVPLSWLHSPFCVTFSFYGDEGEITLVDANWLEEQLRTSSVTVSLNKHGEISQISKLGGTPVEAVTLLHCGNVALQKAKEFSTIVDERLADDAKRRDKGGLISELLSAENDRVVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5A8</accession>
    <name>A0AAD8U5A8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_594175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000239">
        <property type="protein sequence ID" value="KAK1705637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357661.1">
        <property type="nucleotide sequence ID" value="XM_060506698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5A8"/>
    <dbReference type="GeneID" id="85390597"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF27">
        <property type="entry name" value="CHOLINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="528" mass="56458" checksum="58F0B5C2A8A0E957" modified="2024-05-29" version="1">MDRDTKFNDESEATAPNVNKTRSADQHDVAINASGHVQELERNFNLLSLAGVGLVVGNVWPAIGGSILVAIFNGGPPGVLYEFIAVSVCYWTVAASIAELASAIPSSAGVYHWASVTPGRRWGRVVGFFAGWWNYLAWILGAASMASIFGNTVVQMYALNHAGFEAKPWHVFIVYIIATWLACTVVCLANSAMPRINDFGVFAIVAGFLITVITVAVMPGRDGRPPHASSSFVWTEWTADIGYPNGFVFVAGMLNGAFSVGAVDATTHLAEEIPNPQRNVPIALGLQLGIGFITGFCYLVTIMYAINDYDALFESPYPIAEIYRQATGSAAGATGLLALVLICIGLTLMGLYITCGRTLWALARDGASPRPSLLGHVSPKLGMPMWSTVLSAILVTVLGAIYVGSTTAFNAFVGSFILLSSSSYLAAILPNLLSGRKMVAYGPFHMRGWIGFAINGIACSYMLVWFVIYCFPFALPTNAQSMNYACLIWGGFTIFVGLWWLLGARKGYEGPTTTGSAVIEAASHHHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7R0</accession>
    <name>A0AAD8U7R0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sialidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_593607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357917.1">
        <property type="nucleotide sequence ID" value="XM_060506643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7R0"/>
    <dbReference type="GeneID" id="85390542"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="64550" checksum="8F180CC111648589" modified="2024-05-29" version="1">MSTYEMPPASRLTYTPTNTSSLSLAADMSFDFIFPSCEPSTPPSFSFDSSLLDLPYHHNPGHNRSRSNGSVYSFISAADSTPDSVSTRMTTPSRASPPIRQHGPLLLPKIRSQDQAIESPPKRMKASPKPRAPVPRRATPVAPTTNAVFRPAHTRSFTNPETLTWNMPSTYCSQPEEQTPSSLLCSPVIFADDMQSRRASTCSLEGVALEKFGFPTYRQMPSYVPSPAPQQPSEAYMFPSYTPRAPSPLSLSAAATPDPTPSTTLMTYLTGSNPAPSLVRTISFPLRDPNTKHFWWDVRQIRPWTTFNASSVLSLPGAAALLNCPVPAPLLPNPAPTARHPETEAALHSIYASHYLPKLNAALAISSHRPMQLSAPAPSATAKQPELLFTASPAGEPASAATIFGGKPTARVVGLVRSFDRFNTGMRVEGNIKRVEYLRGLAALHHAMREHSCRYGFILTEIELVIVRNGSESVPHFGHLEVTSVQLAAVADDADCEVGEIPLTACLALWGLCMMAGDDAPQQQGRSAVAHWKTEIGAPAEGTRRKALPRDEWMPKPQLAEKREAKRARGWVMPEDPVGRKELGKRGVRYGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7S0</accession>
    <name>A0AAD8U7S0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_189791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357932.1">
        <property type="nucleotide sequence ID" value="XM_060501586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7S0"/>
    <dbReference type="GeneID" id="85385485"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="153" mass="16657" checksum="C7E1D6AA7282F1A2" modified="2024-05-29" version="1">MMRYVAVAPASFSRLTLCCLDAVSAKSNQLTGEGREVCGLRTGGGVITQSCCGVVLGQLLYFFCSILSDPLNALRTWTVSHSLPRLSNVSMFLVVKDLLEGPNDWIFQRCNLGLHHKDIIGHTDNGKQRKASESAELRADRDGGIDQGTSHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U892</accession>
    <name>A0AAD8U892_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1168 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_590332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000152">
        <property type="protein sequence ID" value="KAK1711972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359296.1">
        <property type="nucleotide sequence ID" value="XM_060506324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U892"/>
    <dbReference type="GeneID" id="85390223"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="21627" checksum="57B70593FA18BFF9" modified="2024-05-29" version="1">MSGEGPESIPTSADPRSRRPTKKRALTPVSEHAKHLETLFSKPDQEIRLPPGAGAVAKRAVAAPPEIVTNVQGSSAGAGSGEFHVYKASRRREYDRLRAMDDEVRQEKENDEFERQKAERAAKDEERTRKNREKRDKKKQKGKKGPGAAVAKGGAAAETSTNKEDDDAKEDKDGKSKGAETASTSSGAAQPPGIVIHDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8U9</accession>
    <name>A0AAD8U8U9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_592979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358183.1">
        <property type="nucleotide sequence ID" value="XM_060506589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8U9"/>
    <dbReference type="GeneID" id="85390488"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02234">
        <property type="entry name" value="cupin_BLR7677-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38599">
        <property type="entry name" value="CUPIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G13620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38599:SF1">
        <property type="entry name" value="CUPIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G13620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="121" mass="13037" checksum="FCA13D8B3B1CD3D8" modified="2024-05-29" version="1">MTRPRETVKVLYDYELANAEGKSIVGLEVTYPPNSTTPPRQHAGATVVVNVIEGKLLSGMNGDPPKVYGVGESFMELPRCHHTVGENPSSESRAVLVAVFIVDTEVLTSGYDGLTVLDEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9C9</accession>
    <name>A0AAD8U9C9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_644061</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000239">
        <property type="protein sequence ID" value="KAK1705635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357659.1">
        <property type="nucleotide sequence ID" value="XM_060509722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9C9"/>
    <dbReference type="GeneID" id="85393621"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1705635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="57103" checksum="B946639E873C5066" modified="2024-05-29" version="1">MGSLLPTAIRIDASLLNWHHLSSTASFLILSSLLLGILSQVLTRRLKVPTPLSEEVSDILNRKRSYGANARKLLDKYYERFKSKPFGIDTMDGVKVVLPLASVDELKSHPALSFKASIDNDALVNYTGIGGVDAWGVHQILAKMNPSLGAYVPVFHGMIQEHLPKFLGSPTDWTPVKPYQQFFELVAILSARIMHSDEAARNPAWTNLSMSFVHTAIDYGSALKQWPPFLRPFVAYFLPERLEKEKQWAQGREIVAKSMARKNALGGASLENPPTMLDHLSSGDHADKAGDLDLQLLLQMTLAVASIHTTSSSMVQVLYDLAAYPEYTEELRQEVVEVLESSGGIFTKQSLAEMKKLDSWMKESLRMNAPDLTTFQRMATKPVTLKDGTYIPAGTKMELPTSAINFDASIYPDPHKFDGMRSYRQRQKEGMAHKHSFVSVTRTELGWGFGRHACPGRFLSDVEIKLMFAEFLLNYEIKNLDGQPRSKNVEFGVNVLPDPEHQVLIRARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9E6</accession>
    <name>A0AAD8U9E6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_74956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359952.1">
        <property type="nucleotide sequence ID" value="XM_060513777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9E6"/>
    <dbReference type="GeneID" id="85397675"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="24495" checksum="B9BAC31BB0E253D7" modified="2024-05-29" version="1">MGPRQRAMAFAFTREKGMIATWRYLIFFDTKIDRWIDDTYTSQFLPLLWIDGNNTLSSVHISVPIALKRLTTVCVRVLVRASGRDATLLSTIIQGSGLSEEGLLCRCNCGLGRLGGFGTIRTTAHLGRKYGVFLVQTSHRIRYREISVYLSEGDPLPCHLRDSGTAGTSVRLSRASARRDRDCCSGIRCAFGGRRELGRTFGVRYPDGRVCWFYLLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9R1</accession>
    <name>A0AAD8U9R1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_644214</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000244">
        <property type="protein sequence ID" value="KAK1705323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357591.1">
        <property type="nucleotide sequence ID" value="XM_060509742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9R1"/>
    <dbReference type="GeneID" id="85393641"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1705323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="51409" checksum="4BAB24C424B9DDB1" modified="2024-05-29" version="1">MAPARDDELFTTANAELPTVKNIKTKGGEGRLMHRSLIQHPSMVESASGIYLNLASGKRVIDACGGAAVALIGHANEEVCQAISDQARKVSYVHTQAYTTQPAEELADLILDGNSHGLEKAFFVCSGSEAVESALKLARQYHFENGQPQRKHFIGRNQAYHGNTMATMSISTVASRKVPYEGFSYPHVSYVSPAYPYQYQKADETEDEFTARLLAEIEDEFQKIGPDNVIAFVVETMVGATAGCVAPPVGYIAGARQICDKHGALLILDEVMCGTGRTGTYFAFEQEGVVPDIVTVAKGLGGGYGPIAGVLMHEKVVSMLRQGSNAFNHGHTYQAHPIACAAALAVQRIVKRDDLVARCAQLGKQLEVLLRIELINCKSVGEIRGRGLFWAVEFVKDRETKETFDPKLRFGLRVQERAFEKGVALYPGAGTVDGSRGDHVLLAPPFTTTEEELRKICSVFREALEEVEAETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAR7</accession>
    <name>A0AAD8UAR7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_724500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358146.1">
        <property type="nucleotide sequence ID" value="XM_060512661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAR7"/>
    <dbReference type="GeneID" id="85396559"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF4">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045527" evidence="1">
        <location>
            <begin position="18"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="2">
        <location>
            <begin position="92"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36234" checksum="6B7B24736E6EC3F7" modified="2024-05-29" version="1">MKLSTVAIGAFASLALAHKEVAPGVIKRHADLSKRCASGAAKFKQKRFEKRQEEAGLNRRSGNSSYTIVTEGPYYDTLQNDTCVLAPDVTAGPYYWPRSETLRQDMTEDQVGVPLILDVGVLDMATCEPLPNALVAFWHCNSTGSYSSFTGRDPNTDFRELLESLNVTDFEIGTTDLHTDDTTWLRGMWPSNDEGILEMKTIFPGFYIQRSIHIHAQVFTDWVLHSNGTVKTGNTNSIGQLYFNESISQEIMALEPYVSHTEINRTTNDVDSVYSSGLANGYNPVIDIVPLDGSDITKGMVGYITIGIDTENSPSLSGPESEQGSSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAS6</accession>
    <name>A0AAD8UAS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CPAF-like PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_593019</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358161.1">
        <property type="nucleotide sequence ID" value="XM_060506592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAS6"/>
    <dbReference type="GeneID" id="85390491"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042026192" description="CPAF-like PDZ domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="3">
        <location>
            <begin position="162"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1707945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="730" mass="79615" checksum="EE0EBF7D4BAF2C75" modified="2024-05-29" version="1">MRSSSIAVPALLASAADLAVAQFPNSTIPGNSSEPCAAVSAAWASQHARAPTVVPSVPAQLAYDCLNSVPLGKEAAIELVDSLFPYLEWQSDAAYKADPPPEYDFPAYDLFAAASSIRQNLVDDVYTSEYAFQSALYEEVFGPGHDGHFVYYPDLLTAVFEWTRQRGLVSISEDGSSLPVIKIYEEVISTPETASAVKLINGIEASKFLEDTVNKANWNRDANSAYNSMFFEKSGQATGIGNGYFSSGGRVRYIYQGANTTLTFENGTEVTFENHARVKKDLTGIVDGPSFYAKFCNPLSPASGTPSGTSPSNASTPILPGYPEPVVTTSDGVVSGYYLEGEGFEDVAVIVLTAFENESPAEFQKVAQDFYTAALSAGKTKLVIDFQQNGGGYILQGYDFFRQLFPETDQDGFSRWKESDGFVAAAQIVSDIVADVDIYTSDDDNLISLAESWFNWRYDYNLTNQPFTSYEDKFAPQVFQNTSYTDLMRWNLNDPLTTTNATFGLGIEINGYGNLTGLPQPFAAENIIILYDGVCASTCTLASEFLRLHGGVKSVAFGGLPVEGPIEGVGGIKGSQVLDWSNIYGYTEFLLPYASNDEQKAAFARYTDLPLNRSLAAAVNVRDQILRDNVDDGIPAQYVREEADCRLYWTLPMIKDVTEIWKATANAAFNGGKCAYGGIAKRGVSAKAAVKRSEYLAASSLKERAAPVRREEPVANDRFWQDKYVLKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAV1</accession>
    <name>A0AAD8UAV1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">XRCC4 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_724464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000201">
        <property type="protein sequence ID" value="KAK1707972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358188.1">
        <property type="nucleotide sequence ID" value="XM_060512657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAV1"/>
    <dbReference type="GeneID" id="85396555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053962">
        <property type="entry name" value="XRCC4_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067:SF1">
        <property type="entry name" value="MITOTIC APPARATUS PROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42067">
        <property type="entry name" value="YALI0C15378P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21924">
        <property type="entry name" value="XRCC4_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58022">
        <property type="entry name" value="XRCC4, C-terminal oligomerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XRCC4 coiled-coil" evidence="3">
        <location>
            <begin position="148"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1707972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="38222" checksum="0700C95EFE45D1EE" modified="2024-05-29" version="1">MASGHVLRFPRSDSEGAFVIVQATPTRSKALDVKLVGTDGVEPYAVSLRHDKVASLRVKNSPVSEEEWVSILTAVLHQEPAEGVEAIASVENESVLTLTIRKKGSEFTQRLGAIELSHSPRELIELFDWCALSAQTANEAKEALASTTAKASKLEESVRELKAQLDELVAAKEADESELLEKFRDLLNEKKVKIRQQQKLLASASVEPEKLAQVQQSSQAVVRGHAAAKSRPGKRKTAPAPVDDADSPEESEGKMDVDEVKEQAADLSDQQRDTTEDEDETASEDDDDEEPAAPAPSKHTRSQVSPPPKPKAAAAAAKKEAPPAKRELPFARKKAAPKAPPPPAGSETESDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB78</accession>
    <name>A0AAD8UB78_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_543221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358386.1">
        <property type="nucleotide sequence ID" value="XM_060503418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB78"/>
    <dbReference type="GeneID" id="85387317"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="33308" checksum="C5E8F5AE259FE9F8" modified="2024-05-29" version="1" fragment="single">YAALSYCWGTGTFSEDENELVEQGQTLKANLESRYQPFDTENLPGTVRDAIKITRRLSDPESGLELCLLWVDSLCIIQDDVQDKEVEIHHMQEVYGNAAVTICATMTTKATQPLLMPRLAWSKQVKPCRIDTSWLTVNPTAPAGLRSRTPLSLRAWTLQEEHLSPRLLFWGGQQFSWACGRGEYVEETSSNSVQPPTTHVRKFLAECRTSEPEELWRAWNAIVESYTARSLSNPADRFDALAGLATRYLAAISAYNEYMAGLWRATFAQDLLWHVSKASGPDVGCPGTAGAPSWSWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBG3</accession>
    <name>A0AAD8UBG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_591690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1710013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358709.1">
        <property type="nucleotide sequence ID" value="XM_060506462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBG3"/>
    <dbReference type="GeneID" id="85390361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="261"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1710013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="55593" checksum="29BAFFD850DF2ABE" modified="2024-05-29" version="1">MSHQFHIAGASYALLDPWSQGAGVVRDVLTRWSELDITQIGSLIAIAGTLPTAWRLMQCAWREAYSCIRRFFLASVTIPGGDPVNRSVVKWVLANRPRHYRSFTGRTEVGRASPDRAAALKKTRHTVQYCPHWNTRGLWFNGNVFVVTRAVGDFNSSLSDPSYDGIGGEDLTISCFGWSAHPVQNFIEACREYTDRQTQYFVIIYSRDRYGMSWKAKARKPLRHLDTVHFDLGLKQELLADIRNYLDPKTQMRYQSRSMPYRRGYLFYGPPGTGKSSLSVAIAGEFGLDLYEVKIPSVATDADLEQMFQEIPPRCVVLLEDIDAVWVERSSNQEKISSGNGRAHSPESSNVPNCTLSGLLNVLDGVGSQEGRIVIMTTNRPEQLDSALIRPGRVDMKVLLGNISPKSAADMFVRMFSPDLGCTTHLKMEEIEKLSVQFSSMIPEDTLTPSQLQGFFQVHLESPYHAVESIASWVEKELARADFKEFEFITSNGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBJ9</accession>
    <name>A0AAD8UBJ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Necrosis inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_528750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358566.1">
        <property type="nucleotide sequence ID" value="XM_060503311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBJ9"/>
    <dbReference type="GeneID" id="85387210"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="26581" checksum="DE99E937D7508607" modified="2024-05-29" version="1" fragment="single">DDYAGHPTLGHDKIVPLTQSASTGFEGQLELRFNPFLYVSGGCDPYPAVDATGNLGEGLRPTGGGRSGCDAGGTAQVYVRGGQSQDRTGIMFSYYMPKVRWGKGNNEGHRHYWASVVIWLNQFGCGEDASSVSPVGVSFTTDHLVWDTAPAGKISYASSGVGVDTPTHPKMQIHDNAFSPFTGADGDKVFERTVVSWFSLPEAAKKALSDVKYEKTQVPFTDANFQAQLDAAYRESFYGGLTDQQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDJ6</accession>
    <name>A0AAD8UDJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vesicle coat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_586623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360928.1">
        <property type="nucleotide sequence ID" value="XM_060505965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDJ6"/>
    <dbReference type="GeneID" id="85389864"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="2">
        <location>
            <begin position="238"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="51337" checksum="2400BF18909DC9B6" modified="2024-05-29" version="1">MNQPPDSLSLMTGLQLCLAHYCDQHGPTPLMVTEGLPVPCTTCFDDGAAAYADQDQLRPRTSAPAPAGSLNQTVAMSDALRKMHLNSHRSSSLPASEAENQIQRAAVLRASSANSTINSPASPLSPSAIETPPESPRRISEQQQPRRDSSFRRTYDDYVTKRAGPCENCALTLPQRQGGKDKNDLKAERGPTLRTRAPYARVYGQASPPTSQASSASDTDGESQPERMHRRATGSTTTRSSMSSGRHVSHTHYLDYTSTHEPLIPASFSIVRSSCLRTLSLETLPRAPANPTPSASPQSSNMPAFVTTHSAGAAASGGPIFFGDPVNGYTTAYIFRIPDMHARGHKRVYAFLALSTHKERLAMKTFGFMAAAFRDLASWIQQLAEAEAEKAAEASPLGGPQHHSSYPTMIKPEREGQDRGGSSFLTGGGGFSRRMGGGPGGVALKARGLAELVGMPDFFIELHAKFVKLMLELGVALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDQ6</accession>
    <name>A0AAD8UDQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane-associating domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_654080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362322.1">
        <property type="nucleotide sequence ID" value="XM_060510691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDQ6"/>
    <dbReference type="GeneID" id="85394590"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39608">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G08640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39608:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G08640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01284">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="6">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="18498" checksum="30B5FE3A292CB2D4" modified="2024-05-29" version="1">MAIDRIVQFVLRGAQLVFAAIVAGITGAYLHATQNTSSWDNGRYIYTIVVASLSLLFALIWLLPFSGSFIHWPMDIFLSILWFVAFGLLVNLVGDGCGPIFDWSNVSPRGDACGRNKANIAFCFLSAIVWLASALVGLFWVRRRTAVADSRPAHTGRRRWYRSSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEE0</accession>
    <name>A0AAD8UEE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362431.1">
        <property type="nucleotide sequence ID" value="XM_060510678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEE0"/>
    <dbReference type="GeneID" id="85394577"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="191" mass="21042" checksum="BCC555D31602ED77" modified="2024-05-29" version="1">MEVSIRRVLSSSPQYAEAIVVAFDRRLRGLTSQNHDAPDLPVFLTSLFQRLHDHSECEAVDNESSSAGKRTTDNGARSRTSSTVIPAGSVVPSQTPVSLKREREKDEKDPQKTSKSKKPCHIVTCDNIEKVANEADKKRPKQGTEASFEKQLGIFRAVWGILFPDAGSGPKSPCPRSQTWSRISSLPPLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF17</accession>
    <name>A0AAD8UF17_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360585.1">
        <property type="nucleotide sequence ID" value="XM_060506039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF17"/>
    <dbReference type="GeneID" id="85389938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="337" mass="38907" checksum="186990C0DF0ECE18" modified="2024-05-29" version="1">MCTTDVYTYVYPDGRRAEQQQPTFCSASRNGHLCANPVIYNHPPRQVGYPSPVPMYAPVGPAYPFPQQMPPSPPMSSPRGTSSGNEGSRARRESSSSERKHRQSGVYVNGQRVLDLNRKHRSRNERIVIVDSPPTPRTPPKQFASPYTAPPSPNAGGENPQFRYSHVRRDSLRPVIVDERPRSKVEIEVIDNKHRRHHSSESRHSYASADDEERRRRHREHKEREERKRQEEDRQVKKQLRIAEQNAKIASRTAVPVPPAPLNRTSTGYGSRYQEDLLADALRRMEVVDHLTARAGDEEEAQRRRLMERMTPHRRATVGPGTRRHRVLYDDGLWRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFB8</accession>
    <name>A0AAD8UFB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_707596</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360750.1">
        <property type="nucleotide sequence ID" value="XM_060511550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFB8"/>
    <dbReference type="GeneID" id="85395448"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="539" mass="60998" checksum="72CACC84DB6E195E" modified="2024-05-29" version="1">MAPTSQLLPPVASLSGVGLLALGSVALLYIISRLFLSIPYPEGIPLIGEPDGATRFSIRTYLRFYTDCQGLFREAYDNYTKKGKPVIIPGIGFRHEVIMPTSSMRWVQTQPESQLDPSTAFAEVDQVHWALGHDRYVVDAWQGHLVKTEMNAILENICAAMNEELGTAFDKWFGTNPEWKEIDLFESLKMVVAQAASRFTIGPGLGLCRNEDYLNLNFDIINQLIMNAGASGASPRVLRPVVGRAVNFTIHGKINRLKRMFEPLWKERLETLKFARDDPDHIEPQDHLQMMARYAKDHRQEEFNDLDMMTRRLIAANFGSMHQTSIQATNMLLNILGSDTEFNTITTLRDEVDRVLYADGDNDWTKAKVSKMVKADSVARETLRLNSFGGRAVFRKVLVDGFKTPDGYHLPKGTLISFLGQPAQTDGEVLEDPLKYDPFRFSRMREDAAAKDEKAPPVTFVTTSPEYLPFGHGKHACPGRFLIDFELKMIIAYVLGHYDVEFPPEYNGKRPENYWLTEALFPPNGVKLRIRRKTETKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFZ6</accession>
    <name>A0AAD8UFZ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_629754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362237.1">
        <property type="nucleotide sequence ID" value="XM_060508779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFZ6"/>
    <dbReference type="GeneID" id="85392678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="598" mass="66288" checksum="9196C9098F8FD5DA" modified="2024-05-29" version="1">MRVSQDSITPSKILPPEPLPSFRYPLRIRVTNMADPLSIAGSVAGLLATAVKVYNTTYNFVSSAIDAPESAMQMFQLIEETKITLSSVHKLLHSIDSFPSSRKNMIQLDHLSIVITHSVLTLSKLESIVCQQDGLRSRMKWALWHEKKILALLPLLESQKSTLAVMVTILNSETQEEAIRSQATMLAKVDEILEQNRTLAENLKLLDSEASWDTRSVKFMDDASSIMSRPGSTQSVICGSPSSVFRRPQPLDGSPITTLSRRNFELDLGQSRVYKRTQDRETDRSSFTTSNAPTSAWSMLSGLSISNISILSAFRLPITLKEMNKIAPGSIFSNLLMEQQSMEDRTGPRPLARSDSLSRAVIRGKRLAGTFASKFDQSDDVAYRKLEIQYEGWTTVTVVIVGDSKSLKSEMIDTFVNQTWLMSSSEKDVHIPNRAHYSRHAVRVRGKLLGLDLRDTTGLEGDRSLTQELYKYADAFLILVSKENVVRVEIQDLVNEVSGARPDAPCFLVVTYHGHELLEGVPGLKRIGGVARSFLDSRVKLLSCAVNLPGSVAKVLAQAIVAANRRGLRSLLEVPNSPQLSKVTIKEVEFTGIELSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG57</accession>
    <name>A0AAD8UG57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_636220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360095.1">
        <property type="nucleotide sequence ID" value="XM_060509239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG57"/>
    <dbReference type="GeneID" id="85393138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="125" mass="14102" checksum="0BDAB02C2ACFC9B9" modified="2024-05-29" version="1">MRPKRGNLQCFFPPVFFFFFRTSQVVPGSFHDCLCHTQTQRQTFDRVLPSTYQDTHAGVELVDGCPRHEVVTVVCMFLSPTWCTADCHECKVRNPLVYSTALPRQNPACQNASRCLLVGMSASGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGF2</accession>
    <name>A0AAD8UGF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_733499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361305.1">
        <property type="nucleotide sequence ID" value="XM_060512919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGF2"/>
    <dbReference type="GeneID" id="85396817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="197" mass="21995" checksum="BF80FE1727053BCC" modified="2024-05-29" version="1">MQPYPAMLYLLRPNEMKLEKKGWWSGLLNPSFPFPPLKSGRRLQQSVTFVEIYLSFAEDGERFSVSDADDSCLRICGHPIHIRSHTSPLSPPFEMCVLSRRKIDSLIRDIGRRFLPSVGSGSGNLSTIATPSFKVQTGIRNSGPFSLCVCVVSIRYRCLDLETGPRILFRPSSPPLPLPARKRGSGASQWHARSPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGM1</accession>
    <name>A0AAD8UGM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_20069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361176.1">
        <property type="nucleotide sequence ID" value="XM_060501652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGM1"/>
    <dbReference type="GeneID" id="85385551"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051118">
        <property type="term" value="F:glucan endo-1,3-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005197">
        <property type="entry name" value="Glyco_hydro_71"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03659">
        <property type="entry name" value="Glyco_hydro_71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="14591" checksum="4A79A7EAEB5072DE" modified="2024-05-29" version="1">MAGDRLFNLFDWSQVLEANYRTRDYWCDLVDGAFSWESAWPEREGYGGKIAGDVSPDFLTAAAAHNHSKLYMVPLSPIQYKNSYKTNVYRPGQHALPKRMELILDTVKQADFVQFLTWNDGPESLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UID7</accession>
    <name>A0AAD8UID7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inhibitor of apoptosis-promoting Bax1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_754753</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362091.1">
        <property type="nucleotide sequence ID" value="XM_060514523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UID7"/>
    <dbReference type="GeneID" id="85398421"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10429">
        <property type="entry name" value="GAAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF50">
        <property type="entry name" value="PROTEIN LIFEGUARD 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="30982" checksum="E6A87BA5C4E9C90A" modified="2024-05-29" version="1">MASKTKYAPAPTQDPDEASSYAQAPPAYQAEPTAASDTDRLFGGGAPRSSQDDDLPDDFKFGGSVAEATTDIRNQFIRKVYAILTVQLIATGAVSALSFFSNGYKTWIQAHPGLVFASLFGSIIMMLLTFWKRKSYPTNLLFLSGFTLMEAYTISVIVSFYKAGIVLNAVFLTAGIFIFLTAFACQTKYDFTSWIPYLGGALWGLVLFGFMYMFFPYSSTGELVYGGIAALIFSAYILVDTQLIMRHHHVEEEIAAAISLYLDIINLFLAILRILNSQQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIG4</accession>
    <name>A0AAD8UIG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_389392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363467.1">
        <property type="nucleotide sequence ID" value="XM_060502776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIG4"/>
    <dbReference type="GeneID" id="85386675"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="134" mass="14774" checksum="3C74BD3FA3164D9A" modified="2024-05-29" version="1">MDKKTPRLSRLSHNVELIRMHPRGHTQGQGDRGSSSIKQSAAAGSTPFGPLSSGRRDAFASFARRLSPVEDFLLDYYVHNVVPFSNYEPIRSGFLDDCTISLNHQSVQLASTSSSALNGLFLVTSRHSSHYLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIU8</accession>
    <name>A0AAD8UIU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_753391</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363647.1">
        <property type="nucleotide sequence ID" value="XM_060514345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIU8"/>
    <dbReference type="GeneID" id="85398243"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000001">
        <property type="entry name" value="Leucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008957">
        <property type="entry name" value="PRK12300.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="65"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="218"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="11">
        <location>
            <begin position="829"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="12">
        <location>
            <begin position="979"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1116" mass="125851" checksum="9461EAC9E19298CD" modified="2024-05-29" version="1">MANEAAKALEALQVSKTKELKGTEKRDFLISLEKKYQRKWSEDKIFEVDAPSTKEVPLHSITAAELREQQPKWMGCMAFPYMNGRLHAGHLFSVSKVEFAAGVARMQGKRALFPMGWHATGMPIKAVADKLKNEVAWFGRDFEGYKEEGVVVDEKPTDAKEAREDITKFSTKKSKANAKTIKAKYQFQIMEAMGIPRQEIHLFADASYWLDFFPPLAQEDLTSLGFRIDWRRSFITTEANPYFDAFVRWQMIRLKELNKIKFGKRYTIYSIKDGQPCMDHDRAEGEGVGPQEYTGLKMKVLEWAPKAEEALKSQLPADANVFLIPATLRPETMYGQNAVFVSPKITYGVFKATETDYYVMTERAARNMAYQGLFLAEGVVDETAKIDGSALIGTRVNAPFSVHKDGVRVLPMESILPTKGTGVVTSVPSDSPADWVMTMDLRKKAAYYGIEQEWAELEIISIINTPSGDMIAKTLVEQLKIASPKDTVQLDKAKETAYSEGFYKGTMNIGEFKGESVESAKPKVRQSLIDQELAFVYSEPERKVVSRSADDCIVSLMDQWYLDYGEESWKKTALDWVENTDGKGLNTFSPETKNAFQGVLNWLNQWACARSYGLGSKLPWDPQFLVESLSDSTIYMAYYTIAPYLHKDIFGREQGTGAIAPEQMKDEVWDYVFCRRELDDKLLAECKIPKETLESMRRSFEYFYPLDLRSSGKDLIGNHLTFFLYIHLAIFSPEYWPKGIRTNGHLMLNGEKMSKSTGNFMTLQDVARKFGADAARIGLADAGDTNGDSNFEEDVANQAILRLHTLREWCDDVVKNKSELRTGEYNFFDKVFNNEMNVIAKEAIHQYSETAYKLALKAAFYDFNNALSFYRESSALSKMHVDLVLRYIELQALLLAVIAPHWSESVWVEILGKPTSIQQAIFPEIPETDAALTAARKYISVTASNVNSAESLQLKKKAKGKETSFDPKKPKKLTIFMSEKFPQWQQAYIDLLKEMWNSETKSVDDKALNGKISKMGEMKKAMPFVQGLKRRLQMGEPASAVLERKLAFDEKAVLVDMIEGLKRSANLVEVKIIAVEEGGKKGTDLVTGAVEESLAPNAEGAVPGAPNFLFANVELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ82</accession>
    <name>A0AAD8UJ82_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_629588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362299.1">
        <property type="nucleotide sequence ID" value="XM_060508767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ82"/>
    <dbReference type="GeneID" id="85392666"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697:SF2">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39697">
        <property type="entry name" value="RICIN B LECTIN DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="19915" checksum="C523CB178C8A351D" modified="2024-05-29" version="1">MASQDKHDDTGSDTASEFHTPILTPATTSVAGEDVEDDHVSDVPWPGKHFYIIEKETGKAITIVDDRPVLMDLQGVRDPATMWYCVEKQGYFGFLNKSWGKFIGHDSKSDVGAWAGEMREWESWIPRQHPDGGYQLLSPYWTHTMMQLCVCPDRINLCRRSHGPTLWEFMQVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJI2</accession>
    <name>A0AAD8UJI2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_631332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM234 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361685.1">
        <property type="nucleotide sequence ID" value="XM_060508899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJI2"/>
    <dbReference type="GeneID" id="85392798"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1720174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16998" checksum="85C6D0BC6040608D" modified="2024-05-29" version="1">MTSPDAPESQPGAINYVAGFLLVGLAWGFTTPFIRRAAKDHNPPPHPVLDTDAVKNSWLRSRVYGAFFGVVDLLRNPRYAVPLLINLTGSVWFFLLIGQAELSLTVPIVNTLAFLFTVIGDWWVEKKVISRETLVGMVLSLSGIALCVHSKTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJP4</accession>
    <name>A0AAD8UJP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="16">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_622866</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="16">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="16">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="16"/>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364558.1">
        <property type="nucleotide sequence ID" value="XM_060508345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJP4"/>
    <dbReference type="GeneID" id="85392244"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17942">
        <property type="entry name" value="DEADc_DDX18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000379">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000460">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044773">
        <property type="entry name" value="DDX18/Has1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 16" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="167"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="356"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="582"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1724503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="616" mass="68146" checksum="1F7454CFB7C2E3A0" modified="2024-05-29" version="1">MDAATSKKRKSRDSNGVKISSKKRAAEAEVPAASTTAEAPAKKSKKVKRSKQPEPEPESDNEEQEVEAESDAEDVENEEETAAANFKTAQDDEDEGNGSDLDDDVHAPAKDTADGENDIPNAQQLSLPPAAGAEAHDFAELNLSEKTMKAIGDMGFTKMTEIQRRGIPPLLSGKDVLGAAKTGSGKTLAFLIPAVEMLSALRFKPRNGTGVIVVSPTRELALQIFGVARELMAHHSQTYGIVIGGANRRAEADKLQKGVNLLIATPGRLLDHLQNTPFVFKNLKSLIIDEADRILEIGFEDEMRQIVKILPKNDRQTMLFSATQTTKVEDLARISLRPGPLYVNVDEKQEHSTVANLEQGYVLCDADKRFLLLFSFLKRNLKKKVIVFFSSCNSVKYHAELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKQGTLICTDVAARGLDIPAVDWIVQVDPPDDPRDYIHRVGRTARGSNSKGRSLMFLQPSEVGFLTHLKEARVPVVEFDFPANKVANIQSLLEKLINQNYYLNKSAKDGYRSYLHAYASHSLRTVFDVNKLDLAKVAKSFGFSTPPRVDITVGASMSRDKKTQGRRAYGSQPRNQQSGTGGFYKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJS1</accession>
    <name>A0AAD8UJS1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_783427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362584.1">
        <property type="nucleotide sequence ID" value="XM_060515587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJS1"/>
    <dbReference type="GeneID" id="85399485"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="2">
        <location>
            <begin position="436"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="629" mass="71302" checksum="3B6189CC08723B4A" modified="2024-05-29" version="1">MDDPSRQDSSRLPKAFEKRRQQKQSDATAASSRAVSLEQAMIANLHLEERLEAESKGEPIEACLKRMLSTKSTISTASSFAKRQQASVGVAAKFREIGTGSIGKVFEHPGTTFAYKLSLTKQHDKLWNNYIMHKRSETAFNSLKFYPAWTGRNSQMFLVRHADYPGLLGRESRPVSRCIWISPQAETNSLYGKDLPSSEARPLLASVSAEWQTSFEKRNFKYLALTRLQDITMLEDFVGPRRQMYVSEIWLHVLLAPYTSGELCEEEDEEILHNNEILDEHLESLFRTLSKWQLGYGNEKNSGVHLHFSAEASDDYDNLFRSNDPLGELYYDLELAEVLGANKRIMGNLLDFENETSASSLTSPAEPGFPAVLRVPIVKEFSIRDELYRSLSAGAIRFLLLSLDNLETIKYTSWRGIDRRDRYQRDRANVALLESLPPTAKSVSSREARHDKFHGPFDEPGPSRDIARVAVLACFHLVSFSSLSVLDAMHFFNEVIQLSMPPMMEYLDRWSSLEAVALTSPFLNSKLDEAYTQGLLQQAAAAAMHLPNLKVMELWQTWKPAAILFRYEVSGHTVEVSYGASWDLKLHQDICDGWEVAKHHGNLFFDIQLKVLDIPASADIDAKLRVNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJT5</accession>
    <name>A0AAD8UJT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_413868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362766.1">
        <property type="nucleotide sequence ID" value="XM_060502933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJT5"/>
    <dbReference type="GeneID" id="85386832"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="14071" checksum="40B13706DDCD6498" modified="2024-05-29" version="1">MLPSKVPSRPSPVLVPCLTLSIIVFSFSPHERTEQVWTRQKLLLNPTGSLFHLRVRLRAGPRSLSRRFSSSSHQLLINNKTAPRLIWAAKTLTPYHMFGLLPALHPHLIHRSTQAQQHHQTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJW2</accession>
    <name>A0AAD8UJW2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_628699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362644.1">
        <property type="nucleotide sequence ID" value="XM_060508719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJW2"/>
    <dbReference type="GeneID" id="85392618"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="29887" checksum="41C2687BA7A871ED" modified="2024-05-29" version="1">MQILAYFRYRRSGTRNPKPPPQASSHVQEPMPQSPAAVGPTTYSAPMKFTPIELENQHLLQFTQTMAEERMREEALASQIVEAAYREKYGDQWHLHLQSQPPTLQIRRKPVPFSQSTSRDTSPGATSHYSGTTMHKPSEGSQLNTPSPSSSRSGPQSPLRSEASSSQTEPSASSVDGSNHLHVVNARNPSQSYAAVWPVSYDPPPYTPHRPLSVISEEGTGQTVAQQTLLLAAQKQFVPAAMNNKKKLKNLPAPLSHLTRGTMRKRAAGTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK27</accession>
    <name>A0AAD8UK27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_754103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362749.1">
        <property type="nucleotide sequence ID" value="XM_060514440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK27"/>
    <dbReference type="GeneID" id="85398338"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="628"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="707"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="775" mass="86638" checksum="B54D1E011E04844A" modified="2024-05-29" version="1">MATDISHTPPEYADPEKSLAQGEKLNIKTAHNLHGQDIELENGHLAELEVDMQRVLDEEGEGDYDADTSPFPQVRAVVPETDDTAIPVNTFRAWFLGIVFVFLGAGVNQFFSLRYPGVHIVSLVAELIAFPIGVALAKILPISRFNPDRHFNIKEHALVTIMSNVSFGFGSADATNLIQAARLYGFYIPPGFSVLVVLCCQLSGYAVAGLAMPWLVKPASMIWPGVLSNVALLSSLHSRANAIADGWRITRIKFFMIVGGCAFVWYWFPGLIFTGLSYFTWICWIAPNNLAVNQVFGMVTGMGLFPLTFDWSMIAYNTNPLLSPHWAALNVFFGFAFFFWIITPAIYYTNTWFTSYMPFCTADVYDRFGSLYNVTEVLTNNEFDQQKYSSYSPPYLPATFAFVYGLSFASITSVLSHVYFFHFDEIVHAMKGTLKLDIHARLMQSYKTVKWWWWMVILLVVFGMAVGTAEGYDTGLPWWGVILAFVIPAVYMVPCGMIQGVTNVDANQLNVLSEFIGGYMFQGKPIANILFKILSTDVVGQGLYFAADMKLGHYLKIPPTTLFFAQGFATILGALTQTGVTLWMLGNVDSICTEDQPNGFSCPNGRTVFSSSVIWGLVGPARLYSVGAIYSGLLHFFWIGLILPPITYFIFKKTKSDFIRKINWPLIFVGTYNVPPATGINYSSWYIVNLIFNKIIYRKFYAWWSKYNYVLAAALDTGLAISGIVIFFAVTYGPNAQFPDWWGNTVWSETADGQGLPWLQMPDVGYFGPANGTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKB1</accession>
    <name>A0AAD8UKB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_697520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365937.1">
        <property type="nucleotide sequence ID" value="XM_060511386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKB1"/>
    <dbReference type="GeneID" id="85395284"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="806" mass="88850" checksum="758B9A5DBC38EF1F" modified="2024-05-29" version="1">MACKACRAKKIKCDRVRPVCQNCRQRASHCSYAGERRVRRWTEADADNRRLSTSRNDQGPSVIDLGQRSLPRQPDADAAACHVEQGPCLRSTTGSTHRMPEGTAQNDAASDCLDWSIAIAAPAAPSDWQTMDSNSMASLFAQMAHDSEVILQTPADSTSTQGESLLDKILDGDEDFENLKDASPALWGRTTEGDEYTGPSSGISTVSDLGLNWIREKVPDSDILCETIQDIRNAILTHIRQPKCIAQDLPLAPSTPHRILDISRPQLLEYVDAYFAQVQVVFPILDRDTFHAQLAEIGDGSDVVEKPSWLALLNVVVASGLRASLSDETSEAFRTSVSEAWGYFRSALTYESQIVHGATDLLAVQAVAMMAVFAQGLSSPQRLEYTLSSVASRLAQSIGLNCAPSPEWSLSDVEKKERNRVFWAVYCLDKSIALRCGRPAVICDEEISCPFPRGIDLAHPGSATNATETGEGELNVDFFRYFTKLARIGGDISRSLYSASALFMPVSRLVPASNHLLQDLERWLKSIPIKVRPGKPLGKTLGTQGVSRVQAIVLHLSYYYALCSIFRRGSPMFNEGKRDVEHLIDRKSHISHIEAARSIVLLTKHLDIESFTPAWLVFYYPFTALTTIFVHVMSNPHHSRNQRDIALMETVVGFFGRLEYVTSGEAAFTKTTEFVRQARRVVDSYKNKGNSRNIQSTTSYEDLMTSMEMSLQGDVSTQGRPAEVTGVYARNSTTATQDVNASNITGTSLLPQAGSSQMEAVSEEDHPVSGVPNVREIEISHNGHTIYSDLAGFTVPNMEDSIQVQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKR0</accession>
    <name>A0AAD8UKR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365128.1">
        <property type="nucleotide sequence ID" value="XM_060508228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKR0"/>
    <dbReference type="GeneID" id="85392127"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="489" mass="54403" checksum="8E310501FE567033" modified="2024-05-29" version="1">MAAPVSTVFAHQPAVEQQALRPELRIRRYGRKDYKLFDQDTARGSHLCVGFGAIGKVQVECKYHWKKAQWGVLGSNRNPAGIVYLDISIKQPPGHNLRDARVLITLAEQDSYGAEAGRRWSQKHVRTSLDSDYAVQVTEHFGPQSLIGPQTVTSELKQKAFEPTLGAGGFFEIGGMGTRRSVARRIIDSWTFKGMVKRAKHGEGFRSLEWELKENETDCNPFRQHIFHTGFAFEHSGRPVTMCVEVEGRLKSRMRQGKHKFSKFCTRSSDTDNTTTTRIDLSSAKSAFKKQLDGIAHGLNMAMQKENYETVPVEMPAPMSATFEQISQPTEIPSQEFDVVKNVAVDILNQYSHQQLTSAGINRQRSPAESGSVFSSDDTLVNDSSDQNSVDAPPKPVRFGTAQNSLKVSEVVALALFKWLFMLLKLVGSNQYSQLAAMPISSKGTQASQKYPGDSGSRQTWDVEDEEQSAKVQAKSRPPRAAFVSDELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKX6</accession>
    <name>A0AAD8UKX6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_618472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365851.1">
        <property type="nucleotide sequence ID" value="XM_060508077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKX6"/>
    <dbReference type="GeneID" id="85391976"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="59" mass="6705" checksum="6292DECF7DC4FAC2" modified="2024-05-29" version="1">MPLHLHHLMHANENIAHTLRSVILRTQTRVCAYLLQTVISRAGALRRTQGNGSFDTNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULH3</accession>
    <name>A0AAD8ULH3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_752957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-ulmin hydrophobin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364185.1">
        <property type="nucleotide sequence ID" value="XM_060514280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULH3"/>
    <dbReference type="GeneID" id="85398178"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23508">
        <property type="entry name" value="hydrophobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.120.10">
        <property type="entry name" value="Hydrophobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010636">
        <property type="entry name" value="Class_II_hydrophobin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036686">
        <property type="entry name" value="Class_II_Hydrophobin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42341:SF2">
        <property type="entry name" value="HYDROPHOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06766">
        <property type="entry name" value="Hydrophobin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101751">
        <property type="entry name" value="Hydrophobin II, HfbII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009368" description="Hydrophobin" evidence="4">
        <location>
            <begin position="18"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="10167" checksum="A590EA05DE5A6CCF" modified="2024-05-29" version="1">MKASTVLLGFFSSLVIAAPTTPADSSLVERLSILAPVCQGTPVCCSADVVSGVVSSNCVAPVTPPITTLGFQAACLLDGNRIARCCSLSVAGLAILCKAPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULN9</accession>
    <name>A0AAD8ULN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_753574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363409.1">
        <property type="nucleotide sequence ID" value="XM_060514365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001433">
        <property type="entry name" value="ABC transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="506"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="646"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1088"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1121"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1161"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1197"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1228"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1314"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="82"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="702"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1723354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1348" mass="148663" checksum="9FD5AC8344899128" modified="2024-05-29" version="1">MSSTSNPTSNDDGAIVLQMDNFDRQSSIEKSAPAHVPEQPDAARFSLSGAGHISLDDVEAVDVQIRNLAVTVDTSPSWWDPATYPELAKSKFNPDPSSKNLIYHVNACLQPGTLTAIIGGSGSGKTTLLNTLSERMISARLAQSGHITFNGNEGVHNARHAYVMQKDILLPSLTVRETLQYSADLRLPPPTTAEERARIVEEVILELGLKECSNTRIGDRQHRGCSGGEKRRVSIGVQLLANPSVLFLDEPTTGLDATSAFQLMRTLKKLATKGRNIITTIHQPRSEIWDLFDNLIILTKGSPVFSGPAKNCVPFFEGLGFKLPPFVNPAEFVIDIAAIDNRTPELEQETTERVSQLKQAWIHESKTIFAPTDKAIESTSSGKSPTSKTNKHASYTRQLRVLTNRTFKVTYRDPMGMLASTTEAILMALVTGYIFYNLPRDLSGIRSRQGALYTAAGLQGYLTLMFEVYRLTVDIPTYDREHSESCVDAIPFLFSRRLARLFTEDLPVPFLFSIIFYFMGGFERDASQFFIFFAITVLNHYISVTCAITCVTASRNFPGASLIANMVFTLQSMACGMFIQANSIPVYVRWLKWITYSFYTFGAYCGNEFEGSFYDCPVDGGASNPECVQYTGRFIMESLGFPQNWIWRPIVVLVAFIIFFCILSAIGLQYIKQEMTIARARVSDTDLSAGKEKMKTHSISEIRTIDVGLDDFALALDKRAASGKKLPTKTILNPVSTTFEAGKLNVIMGPSGSGKTSLLNAMSLRLPSSLSTRYRLSGKLTFNNAQPSNSVIRSVCSYVCQDDDALLPSLTVRETLRFSAGLRLPAHMSSDEKSKRAEEILLKMGLKDCADNLVGNELVKGISGGEKRRVTIAVQLLSDPLVLLLDEPTSGLDAFTASSIMEVLQGLANEGRTLILTIHQARSDLFKHFGNVLLLARGGSPAYAGSATEMLPYFQRQGFTCPAHTNPADFALDLVTINLQQETREAESREMVEALISAWQRHARMPVVKTTGELPSINESQEHEAITRSSTGPTNVGHSRKALAFNKANLATPAELGALVRKRATFFVAFPLLVHRGLINFRRQPPLLLARIMQVVGLGIVLALFFAPLKNDYYSVQNRMGFVQEIGAFYFVGMLQNVAVYPAERDVFYREDDDGVYSVEAFLAAYSVLEFPFEVISCLIFGVLADLAVGFPRTVTMYFVCVFSCFGVVSCGESVGIMFNTLFNHTGFAVNLTSVILSVANTMAGVLSIDMPELFKIFNYLSPIRYGTRALAPYSLRSVTFTCDDGQRLPDGRCPVETGEDVLELYKFNVDPNVNIAALAGCVIVYRLVAWALLRAARTRMEGLKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULR5</accession>
    <name>A0AAD8ULR5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362780.1">
        <property type="nucleotide sequence ID" value="XM_060510635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULR5"/>
    <dbReference type="GeneID" id="85394534"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY/ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199:SF2">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY_ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041906093" evidence="1">
        <location>
            <begin position="17"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="37114" checksum="4FAAFF5C51CBA8E6" modified="2024-05-29" version="1">MMRHLVALVLTIVASASPLAVTRGVHERNVNLALKWDILPTNSQQQFRGLSPVSGQIAWVSGTGGTVLRTTDGGASWQSVGPDLSTEDADLQFRDVQAFSAEKAIILSIGEGADSRMYITKNGGKSWTQTFANEEASAFFNCVDFEDDERGIAVSDPVDGKFRLIETLDGGNTWTIVDPSGMPSALEGEFGFAASGTCISTAAGRWYLASGGIDPGRVFRSANGNEWDVSGSAIAGGASAGVFLVRFRDAQNGIATGGDFNVVNGSLHTSAWSEDGGKTWTASEVFPGGYRSGSSWAPGLCGVAVAVGPSGSDITLDAGNTWVTFDTGSFDAVECVDGRVCWASGSAGRVGKLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULW2</accession>
    <name>A0AAD8ULW2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TspO/MBR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_616896</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366301.1">
        <property type="nucleotide sequence ID" value="XM_060508000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULW2"/>
    <dbReference type="GeneID" id="85391899"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.100:FF:000001">
        <property type="entry name" value="translocator protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="198" mass="21332" checksum="85007935451E7069" modified="2024-05-29" version="1">MTTFIPALTLPHQVFENAAASILLPIALGTAVGFSSRPKDTKKTYAAIKNPPGRPPAWVFGPAWTLLYGLMGYSAYRAFHTGLSPTSTLSQIADTKHGATLYTIQLGLNLIWMPLFFLLKRPVAATVDILALLGINSYLAYLWGSVDAVAGACLVPYLGWLSFATYLCAGAGYLNDWDLKGAEARYEAEQAAKAGKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMK8</accession>
    <name>A0AAD8UMK8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GA4 desaturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_790780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367152.1">
        <property type="nucleotide sequence ID" value="XM_060515720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMK8"/>
    <dbReference type="GeneID" id="85399618"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="33899" checksum="17AAF532C6BD6304" modified="2024-05-29" version="1">MSTASHFPGVRTHLVYRKPPSTPEFLNTPTNLYSDAENYRDKREVFVRNIRSEMDQFTTTSDGLEFMKHKVDIKDWSDEDEVREVILRDTQELLKKHFNATRTFTTVSRIRHSDTSGIRKDTTPVYSIHGDLTVRSGLELLEDTVPNMDPPPKSVPPKGRVLMVNVWRPLKTIKRDPIAFLVPKSIKSQERHAQIFSRPEGKFKVFGKDAQDFWLDTASYSEDHDWVFLDHQQPDEPVLFLQWDSASLENFESRMAVFHTSFEDSRFVNDAERASIELKCLVFLDDYMSGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMT8</accession>
    <name>A0AAD8UMT8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_701017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364024.1">
        <property type="nucleotide sequence ID" value="XM_060511439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMT8"/>
    <dbReference type="GeneID" id="85395337"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="108"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="357" mass="40113" checksum="18B10A5ABE748F84" modified="2024-05-29" version="1">MSEPNAPVPRRDVTKSGNWFRDYDSIPASSEPDELTLMLCPRTISAFSLRKKRWSSYDVVDLGPVQFAADSWKRLVLKTEYKEVIWAMVKSYLGHNMGFHDLVAGKGEGLVILLHGPPGVGKTLTAECVAESFKKPLYMVTAGDLGTNPDTLEAKLSTIFDHAVAWDALLLLDEADIFLQDRDYDNLHRNALVFIFLRTLEYFNGIMFLTSNRVAAFDQAFQSRIHITIGMPEFDETLRRGVWKIFIQDLGREHRDGSPPLLSREECKALGTEVTKSWASQPLNGRQIRNCVRSALALAENEGVSPNASHFNKVINLGNAFTKYMTQLQKAEAEEIAQIKGDRLAAMKDIMARESDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW1</accession>
    <name>A0AAD8UMW1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_574007</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366811.1">
        <property type="nucleotide sequence ID" value="XM_060504670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW1"/>
    <dbReference type="GeneID" id="85388569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF4">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="39"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="55244" checksum="D2FAE331BB7BD51B" modified="2024-05-29" version="1">MSYTHTGAPTEFNGTNADYGGDSTTTNLNQWYQSGDQSYILVSAAMVLLMIPGIAFLYSGLARRKSALSQLWVVMMSFSVIVFQWYFWGYSLAFSETATNGFIGDLRHFGLMKVLATPSQGSPLVPALLYSFYQMMFCAVTAALTAGATAERGRVIPCMVFIFFWATLVYAPVACWAWNANGWAFKYGVLDYAGGGPVEIGSGMSALAYSWVLGRRNERMMLNFRPHNISLITLGTILLWFGWLGFNGGSAFGANLRAAMACWNSCLTAMFAAMTWCLLDFRLAKKWSLVGWCSGTISGLVAATPASGVITPWASIILGVVAGVACNFGTKIKFLLKIDDSLDVFAEHGIGGIVGLIFNAFFASSSIIGLDGVNMGVSGGWVDGNYKLMYIQIAYIVACCAYTFVMSAILAKAIDMIPGLKLRASEEAELLGMDDDQHGEFSYDYVEVRRDFLAWTPHQAEPAGEGKFIPQHGIEEHQHMANNGASSGSDEPKPVTPQGEIRSEKAPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN11</accession>
    <name>A0AAD8UN11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_346005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the nucleoporin Nup84/Nup107 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364608.1">
        <property type="nucleotide sequence ID" value="XM_060502486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN11"/>
    <dbReference type="GeneID" id="85386385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007252">
        <property type="entry name" value="Nup84/Nup107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003:SF2">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003">
        <property type="entry name" value="NUP107-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04121">
        <property type="entry name" value="Nup84_Nup100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5 7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="910" mass="102582" checksum="CE44304137135B6F" modified="2024-05-29" version="1">MDGIGPEVEVFANILDDCLANQGTDEDKRARVLGLVNAYHDYAAEKLSQLRKPRRQGSIGNNEMDLDDEEEAEAAADSEEIRVWEQERQTWDLVRRLIPLRYSVRSSTNQQATYSGEDLWRAFLANDQSATERKTILEWLQQGARAGPDIDDLVRELQQNADRGDIIAHGWIHTRSAIKLQKSVIGSSRPLDVHFPEVARSLVNSDKAPLVAELDPDSVIRQGRKLEPQDEYFERAIWVGCFQLLRRGCSLETTREWCLERTEVWRAVSMSALPLASDHGETTLVDDPSGLALWRRMCFALARQGGTDDIERAVYGVLSGDIPSVQRVCQTWDDFMFMHYNALIRTQFDTFLLSQCSPEASATIRSSFAAFDAVQFHGDAATLEQRLIRNLETSPHTSKEALEPIKALQAAIISRDLQRHFYEQGVAITQKANSKEASALMPDHSCRNVDVVTEKFADIKNPDGLRIAVHALIIFDTLDKLGTLKTNTVTMSSDHNRRELQENTITQYISLLRLAGLEELIPLYCSRLHPSRAFQVLSTNLLPITDSEARQEQLTFIHKAGLDVVDFVKAQPQFLFQTLGLDTAQNDAMREFQIMDDGPASLKYGRSIKTDFFGEDPESIDPVDERLIRSVEWLLLVSEAWPYVFSTGVAIYKHFLKTMHLNAARSFANRVPFDSIMRMRSSDFPEQAEDELWWTQDGEFWVNQLEGAGAMDLSPSQVVSDAKVLRELECLVRALDTMETVASLAELSREDPSVKRDFWAKVGNEVKAAKEHVRPLLVDWLGSQGNPCSLNHISRRTNPLVTEDQDLQALREAYLPETILAYVSTLHFAGTTLTRDNFLECMELAATIAEKGSDVAECFTKAKRMKELVECFAACSKALAVASGEKKAANSSSKKLREMGWSRDLWSVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN40</accession>
    <name>A0AAD8UN40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_752498</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364653.1">
        <property type="nucleotide sequence ID" value="XM_060514210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN40"/>
    <dbReference type="GeneID" id="85398108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051526">
        <property type="entry name" value="Beta-Glucosidase_SUN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005556">
        <property type="entry name" value="SUN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31316">
        <property type="entry name" value="BETA-GLUCOSIDASE-LIKE PROTEIN NCA3, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31316:SF0">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE SIM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03856">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042138425" evidence="12">
        <location>
            <begin position="20"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1724598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="45500" checksum="F50DDBBD9A399945" modified="2024-05-29" version="1">MRSIINLAIAASLAAGVVAQPHNHRHRHVKRDTALDQRDVVVVYESGPTVVAYELGGKPISEEEAKKGIADGLFVVVGETTPSSTPLPSASTSKAPVASTSKDAQFFEAKVAKSSTSSTPTPTPTPTPTPTPTPTPSSTSTQAPASTKASSGGSSSSGGKGLTAEFPSGTIPCSHFPSDYGPVPVEYLGTNGWTGIQRTPNYSVGDAAISFIETAVASDGGCSKNSFCSYACPVGYQKTQWPTAQGSTKQSIGGLYCNADGYLELSRPTKKTLCEEGAGGVFLQNDLDDISCVCRTDYPGTESMVIATVPQPGQQLPLTNPNSADYYVWNDSPTTAQYYVNKLGYAVEDACVWKSSKDPLGAGNWAPVNIGVGKSTDGNTYISIFNNAPTSTAKLDFNIEITGANSKCALVDGSYTGGGTGCTTAISGSAKAIIRFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UND4</accession>
    <name>A0AAD8UND4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metallo-dependent phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_578529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364536.1">
        <property type="nucleotide sequence ID" value="XM_060505135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UND4"/>
    <dbReference type="GeneID" id="85389034"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF28">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="70"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="42494" checksum="C025B7035A009DA7" modified="2024-05-29" version="1">MPLFRSSSGLDAILNRPEDDGFATHLLSNPLSTIARYLYEFFPVSHPVVNHNDDAVTVVCVSDTHNTKPHLPPGDILVHAGDLTASGTRRELREALGWIRAQPHRFKVVVAGNHDSCLDKRIRRDDEDDDDDDDDDDDDGSPLDWGDIIYLSRTATTLTIPPRRPNDGNRTYADREIRVYGSPYTPRHGNWAFQYPRSGGAAPYCSSSSSSSSSSSLRKTDVDNDTSADPWCGTIPPGTDILVTHAPPKGHMDDPRGHWGCEMLLAEVWRARPRLHVFGHVHCGRGREAVAFDGLQAAYEDVVLLEAEAFAIAGGSAVGVVGVSRVGGVVIAWIKALLALGWCFLVWGWVLWWRGGRRGTGRTVFVNAAAVGGFRDRLVREAIVVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNS8</accession>
    <name>A0AAD8UNS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_651577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365249.1">
        <property type="nucleotide sequence ID" value="XM_060510460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNS8"/>
    <dbReference type="GeneID" id="85394359"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF3">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="36"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="336" mass="36819" checksum="4DAF46E7E4CE4CBA" modified="2024-05-29" version="1">MTSSKDYVFKEVGETLIQTTAYWKTTNSEEPKGLALAFHGGGFVIGSRHSLPEVEVGYLADANFIVVSADYRLCPQVALREVIEDAIDVFSWCKTEFPAKFEADTGLRINARKTVVFGQSAGALLALHLFLSPSDDQNSTSCEQGALEEPPRAILDFYGVKYVSDEFWHMPLPALAAIPTLPQALTDKIFDEPVMTTTAISLEKAAASQDVVIKRGMPAPDLSVPRNAWLFTALRDGTQMKTIVKDDDLDCVDPVRGFHPKFPPTFFVHGDTDGLIPSAFSERACRELSDMGVKARISLIPGQSHGFDAGLGVDDPGWPQVRDALDFLIFYGNKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPG0</accession>
    <name>A0AAD8UPG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_610524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368232.1">
        <property type="nucleotide sequence ID" value="XM_060507594.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85391493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18966">
        <property type="entry name" value="chromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="972"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1357" mass="153084" checksum="8EF00C5DD9A1EE81" modified="2024-05-29" version="1">MDVSGLFVADDKQPDDDNISINSTLASEHDSDEEWLVEGIRAQCREGGRDKYLVEWTGYPIEEATWEPEENVTDELLGEWKDTQAKQASGEEKPFDILAWQESVVKRQEDKYQRHHQRNVERKKRGIQLRLWEGETKADYYLSDEDVGEDDYNAVFPPPKVVGRNEDAFHSDTHPSNIAPKQEVAEKPIPQKRASATEKPKSPTRKAQSSSSPQPRSQPPSAQAATTGSQGTAKKKPLPSRVVNNATTSRLPNSATATARTTHKAKKTAGSSRTMVRSQTSGTGINVFAAGKQSKQRRQLVQNVADPNKDARLFSNHRLRRKAELQGREKADVAPAAVPTKLFSISRGPPPGITTGTNTYPSTSTKASIPRSVLKRSVDDLSTRSASKSSMTASERAGVSHPQNLGQSQTIQPTTKKRKSVQFADVPLVDKPEEMDVDYPTARPRRLKSPPMPSDPSQSTQPPAKPQSILRKLSITNYKSRSTGQNHDKTVVLGPQGSKDIEMTFDNVRGDSDAWHSQFVDEKLLHFARNFTAKTFASQRAIVFERLLSNGSVRPKSTNDQVAVERAAERLRSGSFGVACFYEDFLIVIYPAECEDWKRTMPEVEANSPANGCLKYVIFKPQPAVKKPLPIRQVNTSKIASRIAIFRDLLRLDYHTILPPGIRNVRHNFYLAFPPSRVLLLEAVSEWLRSENPECRIFSTKTGGDWAAFTNPKIVAQGVFIVHEAAADSLRRFPGLLKLLLHKSSASYVFWCIGESLQLSPAYPSIRSMHIEMPKLGTFELTRFFPHGNAILVTPSFLVSEPRRAFELFQWYNRTYQKPNNNQKIVAAASLREYLRDLAHERSARRDDLMADGDLTRQWSMSKREDIARIAGLSKEDCTARFETWAIVDGLQSAIETSIVPDEQLEAIVFADGSIDANDEQSLVNWFGCWSQTRFDQFRKFHVLGTDGTSDNSHLIKDGNIPIYPPGVGRDLGAGPNLDVHGPRQTTSGADNDLGPGSGGSKLLGGLSGHHFLTKLKAMANRNERPKVCPFGKLFGFAVSYYEDIVDTADSYGDFHRDFSTFDKWMEWPWPFFSSYQEHFKQPAAPYHLPPTFNTYFAFFYTPEDDHPSKPPPRHPWLAIWRVREPYAPWKGTELFIWDIAAKDRCSKANEIYEYQLLQAQQHLIRMVRERSEGKHRGLPLLEVWCGGFETEPSEYTLPVDVTFHNLDVMMSDCKQHLPAADTLLLRRGFRKICPGDAPVGQGHHPTDSSMDIDMIGGHRNHGGESKIIFHPPRAINPTGQSRCENLFYTWVMNIDRHNPRPAWPYTFRPTTEWYQQQVAENRHFEHLNVASWQRVFEVLRLPSEKSKAESQESAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPU6</accession>
    <name>A0AAD8UPU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_792439</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1725004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365059.1">
        <property type="nucleotide sequence ID" value="XM_060515759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPU6"/>
    <dbReference type="GeneID" id="85399657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042267675" evidence="5">
        <location>
            <begin position="23"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="330"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="59937" checksum="3BB1B78D7E1BCE42" modified="2024-05-29" version="1">MTLRVSIVFSLALLGLSQVVQALVPRQEATFSNPVIWADLADDEVFRVRDTYYYSASTMHYSPGAPLLRSYDLVNWEFVSHSVPELPGSKFSLNGSDSAGYVNGVWASSLGYRESNGVFYWYGCIQGTDETYIYTASSPEGPWTHHDPIPKCYYDLGLLIDTDDTMYIAYGAIDIRLAQLSADGFTEVRNELVYTEDAHRYIEGSRFYHIHGNYYIWVTKPGDEQHVLKSTSGPWGPYEIREVIAQMKAPIEGAGAPHQGGLVSTEDGKWYYMAFIDVYPGGRAPVLAPVEFDAEGWPSVVTDANGGWGAEYAMPVTTSKTVQGVGSYVDKFEGDALNTRWEWNHNPDNDAWSLGPDGLTLHTATVCEGLYGAANTLTQRIIGPRSQATFRLDISGMVDGDQAGVAALRQLSAYIGIHKVDGASKLVYVDEISMVVRDSLTDWVTTSNGYVKAEGPTISGSDLWLRIKADISPPVAGSSAWPNATFWFSTDGDNFEQLGPVYELNNEWFFFMGYRFSIFNWAKTRLGGSILVREFELEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQD7</accession>
    <name>A0AAD8UQD7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_571329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368116.1">
        <property type="nucleotide sequence ID" value="XM_060504398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQD7"/>
    <dbReference type="GeneID" id="85388297"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="158"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="668" mass="76382" checksum="61E93DE4B2FAE390" modified="2024-05-29" version="1">MSTTLTVRERLTLCKWADSLPGDITPTLTRGAEWVKSEFGKDVPEAVIRTILDRSDTTDDFQAYNDGEIAPLIRPGFGKEYWEMPDDDAAFPSAVQEWKASTLTWGEIAILWFVEKITNKPDWHVKVFDEEIVAKWKQEVMAVEWKAVGLKYAYFDDDLFKFAIAELCEKAKLFEATGLIPIFDASSVVIKSDSAITPEVKEELKQGVAALEDIPENEKDWHPGSDGKVLDLVHPSLWPLVFGKSRIVADKRILLKDTLAACGTGDVIPVPKKRYPDHQSSDDLWSTKYQWLPCDIDIEEGKPKIMSYINNLHPQHHAGLYTTIERVLEKALPMWDLIYRWHEDYETLRIPCESARTQCLAECTRWCCPENRPVDPDEAERDEDGFNDDWGGYSAEEPSRELWRRDKIWFERTHPIEKPPIPAYKPMGLQPKDVNLTSGFFNHADRIQVIVKLANIHLTPEKPTYDGGSWHIEGQLNEHIAATALYYYDNENITDSHLAFRTVADREELMGELNYEQGDFHTIDRTLAINSHADTNQRLGSVLTREDRLLAFPNVYQHCVAPFELVDKTKAGHRKILALFLVDPRIPIIGTANVPPQQRGWWREGAAPGDRLGTLPPEVTDMVFDNMDFPIGMEEAKRIRADLMEERTAIAEQGMGVMTTMEWNFCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URS3</accession>
    <name>A0AAD8URS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_198384</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367697.1">
        <property type="nucleotide sequence ID" value="XM_060501645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URS3"/>
    <dbReference type="GeneID" id="85385544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041915898" evidence="7">
        <location>
            <begin position="19"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="40"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="26603" checksum="65A9C76C2757EC2D" modified="2024-05-29" version="1">MHFSTVLGATALATLANASPLVRRQGPAVGQVISKCTQNGVVALTFDDGPFTYTSQLLDTLAANNVKATFFVNGNNWGNIETAPGPDNIRRMKAEGHLIGSHTYSHPDLSTLSSADRISQMTQLEDATRRIAGFAPKYMRAPFLSCDAACLSDMASLGYHVIDTSLDTKDYENDTPETTHISAEKFNNELSADAAGNSYIVLSHDVHQQTVVSLVQKMIDNLKSKGYRAVTVGECLGDAPENWYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URX1</accession>
    <name>A0AAD8URX1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_695773</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366824.1">
        <property type="nucleotide sequence ID" value="XM_060511361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URX1"/>
    <dbReference type="GeneID" id="85395259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016162">
        <property type="term" value="F:cellulose 1,4-beta-cellobiosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041952383" description="Glucanase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="458" mass="49979" checksum="10B561ABF4A7B19E" modified="2024-05-29" version="1">MHSLAIINLALATVAAAQKVGNLVPEQHPRLSWQNCSKSSNGTTSCATIDAGVVLDAEWRWIRNANSISNCYTGNQWDPAQCNTTASCTSTCALEGADAQSYRDGYGITTTGSNTLSQKFVTQYAFSSNVNSRVFLLEPGGTDRYQTFVLMGSELAFDVELSSIECALNSALYFVAMEPDGGMARYPTNEAGARYGTGYCDASCPRSNRFVGGKANVEGWVPSETDQVRGTGNYGACCAEFDVWNSNAHSYSMISKPCVDTGYGVCQTTDCDAANAGVPGQVLCDRFGCDYNPYRLGDKEFYGKFKTVDTSRKFTVVTQFSEDNIKQFFIQDGKRIETPAASYPGFPNTSGLSPDYCKALPTNFQDPEYFAQVGGYPRHNEALRRPMVLTMSISNDYWANNLWLDSTFPPDRAGLPGAERGPCPSWGNGPEPQEVERYYPNAKVAWSNIRFGPIGTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT27</accession>
    <name>A0AAD8UT27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_224055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367308.1">
        <property type="nucleotide sequence ID" value="XM_060501759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT27"/>
    <dbReference type="GeneID" id="85385658"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="28871" checksum="1F84AFC2F5CEB389" modified="2024-05-29" version="1">MTGRSETLVSAAHHTLVRLANVRWLGWQTPRLVQAETSRGMPFTNRETNGIVTLGCRDIKKENVTCPLFRPYLPEKQQPPRREPKKEKTCGWEQTRRHPYVRPAALPMCSAPSQPSLIAKYTVRQQNKAYACNTRQHDLIIPSALSGISRSLPSNAPEPGFGSPLRSRSPVVCRGQRHASSYRGILCRLCVCVQCEGAGTNQINTHLCVEVWKAAFARKERKANDTASSEPKCDPYTVMSCAFPSSSILPSCIPSAEKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTA5</accession>
    <name>A0AAD8UTA5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_280585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366005.1">
        <property type="nucleotide sequence ID" value="XM_060502129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTA5"/>
    <dbReference type="GeneID" id="85386028"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10304">
        <property type="entry name" value="GST_C_Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000199">
        <property type="entry name" value="tRNA-aminoacylation cofactor ARC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="236"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="45970" checksum="B445F19234B42A6B" modified="2024-05-29" version="1">MLSSLRAIRPSSRSISPFRFARMASNTTYTPNEETEIQQWLTTATRLQQSKPDEASPILDTLNSHLSTRTTLLGTKPSKADTALYSAVRPLVASWSPEQRTGEKGYPNIVRHLDFVQNFPAFAADVKADDKVKVDLDEVLYVKPPVDAKAEKERLKKEKAAAAAAGGAAAGDKALPDRTKEPKKDKSAGEKVKEVVTEAKDKVKAAVGAGEGQPKKEKKAKAPKPQKAAPAAAPLSPALIDLRVGHILKAIKHPEADSLYVSTIAVGDEPNDDTTEYEGQVCRTVCSGLNGLVPLESMQGRKVVVVCNLKPVKMRGIKSCAMVLAASPKLKEGEVDDHKGPVELVTPPADAKAGERINFEGWEGEPEGVLNPKKKIWETFQPGFTTTDDLAVAFDAGVVEALGKQGLGKLKTKSGGLCTVPSLKDAVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTZ6</accession>
    <name>A0AAD8UTZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_569791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368852.1">
        <property type="nucleotide sequence ID" value="XM_060504230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTZ6"/>
    <dbReference type="GeneID" id="85388129"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000102">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000167">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="320"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="526"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="569"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="63485" checksum="BE5F881E0BDF5D77" modified="2024-05-29" version="1">MSVTIEKILAASPATQRGQPTQLSTDNKGERIAYAAGKSIFLRSIDNPSVCKQYTGHTAATSVARFSPSGFYVASGDVSGSVRVWDAVEAENTKGEYHIISGRINDIGWDGDSQRIIAVGDGKERFGHCITADSGNSVGEISGHSKVVNSVAVRQQRPLRAATVSDDSSLCFLHGAPFKFNSKNANAHKGFVFGTAFSPDGSQLVTVGADRRIQLYDGKTGEPTKSIGEGEHTGSIFAVSWSQDGTKFVTASADQSVKLWDVESGKATQTWKFGDGVSIGDQQVGVVFPHGRTDGLIISLNLNGDLIYLNEGSDKPSKIVQGHNKSITALGASSDGKGQTLWSGSFDGRVCQWDVATGTGSVVDGQAHTNQVTQFSAEAGQTYSVGWDDHLRIVDESANTFAGEALKLAAQPKGVAATDGKVYVATIEGVDVYQKGQLLSENRLGFTPGTVAAYGSTVAVGSGNSVKIYAADGSGKLSETKSVDKSTALISCLSFSRDGQYLAAGNQIGKIVAYKTADWEVATDRWSAHTARVTCISWNDAATHAVSGALDTNVCVWSLAKPGSRVKALNAHKDGVNGVAWVEGGSKIASAGGDAAIKVWTVAGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUA2</accession>
    <name>A0AAD8UUA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368715.1">
        <property type="nucleotide sequence ID" value="XM_060510197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUA2"/>
    <dbReference type="GeneID" id="85394096"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42106">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
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        <location>
            <begin position="582"/>
            <end position="592"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="663" mass="70871" checksum="045579A22A7B044E" modified="2024-05-29" version="1">MDRTMDLRDMDFESAIVDDDKDADVPVNALNTPQRLGRSPLSKTRSMSDGGGTPSKLTPSPHIADGRQASKDDNHIRDTATTPVTPHRTEYPLRGLSLQMPANRDPASPASNSSTAFTKPAPLSPKLDHSQIYASPTNILPRRSRGLDFSRAATSLHHSTLAESSPDSSPTIGGRGMNIPGRRSNDYGQAEQTTNSLWSMMGNHERMTVSSSLGSANQIGSDSSSDSDDDDLMDEDMDEPYIGTPQANKTAPPLGTQPMMAPWGGSPAMNSLMSFQHRQRQRKQPKKKHKLPLGLGFSPSTNAGVSKSPPNNVPKDMSAHSRRESISWQANQLHISGSEEERGDNIDGLLSTPSRDGQRPTVMRRVVTQRRNLLPKTKNFARIRAALFEEGAPVETETQREAEVVRQVRESDVDLGAPRQQTVPPATTHSSPNLGNQDQSLDDIPESMITDSALNLSGSFKQQALKNSKGTKFWDTFSESSSIGGARTTPPPPNGGLPRGSSSGMSEDICMDSPSLGPTAGFAMAASSGESQKGDTPLLAQGPQPAPSAAEITRRINSKRRREDDYDPVSLKRRAVSPGMSVHNSPIMQSPMQRDVAPWGSRPGSNSGDRGGSGAPSESGSLGGGTPGSGANANGRVVNGNKGRVGFQGMVDTNDGLMRMSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVU8</accession>
    <name>A0AAD8UVU8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368793.1">
        <property type="nucleotide sequence ID" value="XM_060513678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVU8"/>
    <dbReference type="GeneID" id="85397576"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="51355" checksum="0F1194103FC9A7F6" modified="2024-05-29" version="1">MAAAATATGTNAAFRQRYAAVDMSPAVEGAGIVPRFFIDAPRLAVRDGGICNPNYHSCVDVGHPETCCANTNYCYVKPDNSPWCCPLGSLCDSNCPATAYQCPTTITVTATVSRPSTANTASGSAVLTTSLSTSSACCGRTCPSPSAFRCESQFGGGCCSYGQTCVSGGRCISTLSATPTSSATGGLKPADPACTATTQHACDDGAAGCCDNLMHCTVVSGTAGCAAGNPTATGDVGYTTVPEGGTGGGLSTGAKAGIGVGVAVVGCALAGALAWFCFVRRRRRGTVTGTATMSERSGGGRSRGTGAGRGGAGVSGVGSERPSRGVRALSDVTSGSRPNGPSRGATQDYFGPDAVAGPYTETGEVDMTAADGSGIGTGAGVGAGRVGTPGRGRGVPLQAHSPNDVVAPVEIGDSGGKRGYGYGYVHGYGHSVTSVPEEGREGGPQEMQTPGSEEETTQGRYELYGSEMASPVSVGAPPSSIVPTPSMMTPRSIASVSMFDRSPGPAPSERERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVX7</accession>
    <name>A0AAD8UVX7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cwf18 pre-mRNA splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_608151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368838.1">
        <property type="nucleotide sequence ID" value="XM_060507464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVX7"/>
    <dbReference type="GeneID" id="85391363"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="209" mass="23185" checksum="B5804920D09618A3" modified="2024-05-29" version="1">MSSSQATLSAVIDERKARLAKLKNLKRKQPADEIVAPESERAASPPTEPDVTKLHLSGRNYDPETRGPKLGFEAPPTQDLENPTLEELAADIEEDVKQKAAEDAQDDKGIDLFKLQPKKPNWDLKRDLEKKLDILNVRTDNAIAKLVRERITGAQKAATQTKQVDAGSREGDAAGIDGIALVEGVRVREREEEDERRENADEEDEDLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWQ5</accession>
    <name>A0AAD8UWQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Ubiquitin-activating enzyme E1-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_649326</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367775.1">
        <property type="nucleotide sequence ID" value="XM_060510263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWQ5"/>
    <dbReference type="GeneID" id="85394162"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01489">
        <property type="entry name" value="Uba2_SUMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000618">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000003">
        <property type="entry name" value="Ubiquitin-activating enzyme E1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.20:FF:000005">
        <property type="entry name" value="Ubiquitin-activating enzyme E1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028077">
        <property type="entry name" value="UAE_UbL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14732">
        <property type="entry name" value="UAE_UbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="13">
        <location>
            <begin position="156"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-activating enzyme SCCH" evidence="14">
        <location>
            <begin position="450"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin/SUMO-activating enzyme ubiquitin-like" evidence="15">
        <location>
            <begin position="584"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="672"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="680"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1727720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="764" mass="83553" checksum="0F781488D25D882D" modified="2024-05-29" version="1">MDSTAEAGAAPAATAAEATAPAAATAPTPASAPQQQQQPAQTEAIPAAPPPAQTTQQQQQQKPQQQKPQQQQQRPPAVQTRDRFFQQSLGGSLNANVKKVRRNPRQSPGASDHATYPASRLSSNGVPFACSRSTIFSPMMGFDAIEESMELTYNTQARVLMVGAGGIGCELLKNIVLTGFGEIHVVDLDTIDLSNLNRQFLFRHEHIKKSKALVAKDAAQPFNPKVKIVAHHANIKDAQFNVKWFRDFNIVFNALDNLEARRHVNRMCLAADVPLIESGTTGFNGNVQVIKKGVTACYDCTPKETPKSYPVCTIRSTPSQPIHCIVWGKSYLLNEIFGASEDESAFDNSADADNAKEIEELKKEAAALRTIRESLGTDAFPQLLFDKVFNADIMRLASMEDMWKSRRKPEALDYKTLSEQSAAALASKESILQGGQQVWALEENFAVFVDSLDRLSKRMQELKKAHKEDASGPEPLITFDKDDEDTLDFVTSSANIRSSIFGIERKSRFDIKQMAGNIIPAIATTNAIVAGLCVLQSFKVLRGDFTQTKEVFISPHNPARLLNSSKYRAPNPDCPVCSVYQTSVTVDMSRATLKDFVEDFVRLELGYGDKEFALNNDVGPLYDPDETENLSKKLSELGIKEDSFLTIIDEDDEEPYVNVVISIQESKEPLTDKPIQGLVADKKPEIPRKPKKEASAESNGTSEPNGKPAGEASEGTPNLKRPRPDDGDEPIEAKKAKVVATTSGSDDVVIVDDSTGGAIVIDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X899</accession>
    <name>A0AAD8X899_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_657668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000205">
        <property type="protein sequence ID" value="KAK1707741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358119.1">
        <property type="nucleotide sequence ID" value="XM_060510978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X899"/>
    <dbReference type="GeneID" id="85394877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF7">
        <property type="entry name" value="ZINC BINDING OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="22"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1707741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="38982" checksum="D61B9B6CDB6E9F4C" modified="2024-05-29" version="1">MKALVSNRSTPARIFNFTSGKSIFKGAHVIDVPKPVITGQEILVKVHSVALNPSDYKHIDVISPKNCIVGCDYAGEVIEVGKSAVESWKVGDRVAGVVHGGLHHDRGAFAEYLKAEADLAWKIPQGISDEAAATYGVSAVTAVLAMNVHLGLPWPDELKQNPEASTPRRTVFIYAGSTSVGLFAIQLAKLAGCTVVTTASPHSNDLVKSYGADHVFNYRSENWVQEVVSAFPDISLALDCISEKGTGPLTAKVLQAKGGKVVTLLDQGESKVPGVKYDMIMLYTVFGKEFSWLPPIGPKFPVDLEHRQALAQFYAILPRLTEVLRPPPIKEMSGGIDILLEELDQLRKGKVSGKKLVVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8M4</accession>
    <name>A0AAD8X8M4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000330">
        <property type="protein sequence ID" value="KAK1701890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357072.1">
        <property type="nucleotide sequence ID" value="XM_060511044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8M4"/>
    <dbReference type="GeneID" id="85394943"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="15418" checksum="A69D1819D4D62099" modified="2024-05-29" version="1" fragment="single">IIKLVKSEVTIIISLIHSLVGDIVELLGETVEIVGEEKEQIISCVLELVFEIIYCLKHVIKVLGCSIFELLGPIVFVLLTVVFHLLCSLNGLIEGLLELVCSVLGGVIGLLLEVLAGLLPIVLGLVGGILKAINLGGLLCSVGSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X916</accession>
    <name>A0AAD8X916_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000255">
        <property type="protein sequence ID" value="KAK1704897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357507.1">
        <property type="nucleotide sequence ID" value="XM_060509754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X916"/>
    <dbReference type="GeneID" id="85393653"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="196"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="778" mass="87694" checksum="34447C760DBFA9F4" modified="2024-05-29" version="1">MIVCKFCQTTVLESGKRWDYHHPDADSFEGSLRSQCVFCTRLAKGLGEIKPWFDHELKVKSLFRWNIRQAAQIRETKGHVSVTFRPVPGRAHGNVKSEDLPEVTFYLFTEEDLGDIPERHELGNRTDSGASKAQMIDWMQDCISNHPKCIRSHSIKSFIPTRVLDVGAPNTNNNDVTPPSHIRVIDTTKEPIAGPYMTLSHCWGTGSFIRLTETNVDEYTTNGIPWTKLQASNANFADAVQVVRTLGLRYIWIDSLCIIQGQQHGEDWNHEAPLMHKVYRNSWCNLAAADSKDHTRGLFRERTAEVVPVRYESQQPSVASGDRVWRVLPADLWDRDLLGSHLYTRGWVFQERMLSPRLLQFTSTQLFWDCATLTATESLPQGLPAPLDTKSATDRHWRERLQSSALSVRPLAGTAEDSLEEFWKSAVAAYTNCDLTYGKDKLAALWGIAKLLRDALGEEYAVGLWGINLAEQLAWRVVDCSTSERYGEKEKVVVPGGQAVGNPSWSWTSLKGEVEVAPRVPRLPRFYTACDHGGGNVRFQIKKPLFGRFEGEHSTVWRDEVVNMTRKLNRASERVSEKARMSGVTTITPITEDIVEEDVGKDGTPKLAGQGVVTQPETKREFAMDKPSELLSTSLRIQAHMCRGTLEAAGESRWTFMYPGLNQTDALIEAYPDIQPKENTAPCEMLLLAASKLLQNRWGRWFLDDGYVEDEDVAEVNYSGTGILVEKVGEGRYKRIGAVVFRQVKRESWACLRRACGGGGMVLEDELQVEDGEKIWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9H1</accession>
    <name>A0AAD8X9H1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_656887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359047.1">
        <property type="nucleotide sequence ID" value="XM_060510913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9H1"/>
    <dbReference type="GeneID" id="85394812"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284379" description="Secreted protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="789" mass="88497" checksum="FCE8FF6F6DA6C3AA" modified="2024-05-29" version="1">MPRHSFIKSLVFSSFIFTSLAGRGPVKHPKPYHEVSQLPGNDYTGSPDSTTADHLNARQETTVDGLTSIDTFTYKGETWTAYEDITRFDGPLVLVSASGSRREIKRYVEASTDESVSINRTVDAYFGLDPANDVNLKQNDVLAERLLQDGEPIEEHVRDVIDLSFLPWDVYLGNVQANDTMALDWQSMTKNYAPWNDMLEAADGTHSNYTFDGLLNGWMPASRKIYRGLVDTTDWVDITTFADVDSPDPDVVHIWFSIKYVKGGVLRAQKYALDYKQFLPLKAHPTADDFYPALMRFADYWDSHVKDEISLTLPDESWSDMGKHAFAVELVGRAGGVTPRYGAFERDYGGSEYDGFQDIMTMSLTANLAWGRFAQAKAILENYMDWYVYDNGAIKMRGPAVPQFGMSLSLIARYVQYTGDTAFPEKYKTKILAWANMLTTRQDENMKLPEDDPYYGLISGWSESDAALRNDAWRFEKPYWNNAAFAARGLKDLSKIETFADHANDWNTRAEQLINQTSLKLDQWIQRNFTPAYVPVLPNETTHVLEDLAEKGDASSQWWPHRVYSELLQASVLSSNHTDMVIDSMRAYGITSVGVVANVTPLKADTRDILGFISYGYALSLLLQDRLDEFVLFLYSHRYHVYNRGLWLAAEVAGTGGGSSTYCQPSQFTVPVLLRAALLFDHPDKDALLVGRGVPRKWLSKGKVGVQRAPTKWGSVDLDMQLDAKAGTITMVLGFSKAPPAEVWVKLRIPEGSQLKTVTVDGSATEWKGEEVILKLASTARNATVVGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA03</accession>
    <name>A0AAD8XA03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_762733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360039.1">
        <property type="nucleotide sequence ID" value="XM_060515208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA03"/>
    <dbReference type="GeneID" id="85399106"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="275" mass="31543" checksum="77C1A4F2785E8EF0" modified="2024-05-29" version="1">MSEGKYAYPNDDRVDLQHHLWLITLDGELATSPGRETARRVLDLGTGTGIWAIDFADAYPGSEVIGVDLSAIQPDLVPANCSFEIDDLELDWPWEQPFDYIFNRSCAGSWSDFRSMIQRVYDHLEPGGYFEVQDLELPSYCDDGSVPLDAALYRWQHALVDASNEVGRPINYALDCLDDLHNVGFVEIRHQIYKWPFNNWPDDPKLKEAGRWNCANLDMGLEAFSLGLLTRVKGWTRDAVEELCAEVKKEVKDTRLHAYWRQHVIYARKPRHPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAC1</accession>
    <name>A0AAD8XAC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_656933</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000164">
        <property type="protein sequence ID" value="KAK1710916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358976.1">
        <property type="nucleotide sequence ID" value="XM_060510916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAC1"/>
    <dbReference type="GeneID" id="85394815"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="22"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="3">
        <location>
            <begin position="229"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="610" mass="68313" checksum="0A4BB5F54B0D43C5" modified="2024-05-29" version="1">MRLINTSTLQLEDFFDSDLPKYAILSHTWGPEEVTFQEWLLWQEDDLGSRKRTNSKRGFQKIANTCRIARQEGISHVWVDTNCIDKKSSAELSEAINSMFAWYRGASICYVYLEDLEPGGVARADLRQCRWFTRGWTLQELLAPADMTFYDGTWEPIGTKETLAYPIASITGIDVDVLIYPQTLSSACVAKRMSWASSRQTTRTEDTAYCLLGIFQIHMPLLYGEGHEAFRRLQEEIMKVSTDQSLFAWDWTEKTMDPRRDLWVTLLAPHPSAFSGCGQVVKCRTAADDNWSVGKEFTMTNLGLSMTLPLIKTASSTTVYAAINCKHDIKDDDDTVICIPLWTTSFTSTFGRHRSRPQANLPIPLANVSMPARYAARRQQQQQPGRGSSVSVSYFPRFSELPGFKMSRSFQKQVLPVYDAEPDKPPELLFQLFSCNDALESWQVGDDAEADPQEYLQTAAHASKTFANKEVHAFCVNLINHGGSSSSSSSKKAPGPCTYPRALSRSPELTHRDNISVYDTRSLHMSSSLMEEDLRCAALAPGRLVPRGGWQISSFPPAKFPNSPVPGFRRPRPSLCNSKSSPGQAVLVPILSRPESYQSFLSLAIALITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAG7</accession>
    <name>A0AAD8XAG7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDZ83DRAFT_658262</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000265">
        <property type="protein sequence ID" value="KAK1704417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357429.1">
        <property type="nucleotide sequence ID" value="XM_060511027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAG7"/>
    <dbReference type="GeneID" id="85394926"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="46"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1704417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="519" mass="56850" checksum="303E2DDE2415E39D" modified="2024-05-29" version="1">MAARGDLESHREKHPEDLVNEVPESSSSDSEDDLKPHPPMYWKIIAVILISCISFGSSWSSGITGALKSTLKKELDINNKQFSLLEASEDFMVTLLILTSGIVTDRIGGAGAMLYGNIIYSIGSIIVAAAAQTRDFKLMIGGRVILALGDIATQVAQYKVFSSWFSPNNGFASTLGLELGIKKIGGFVGKSSANIIAKNTGNFAWVFWIAVFMNVFTNILTLVFYRFNTIAHKKFGNVTDPATGEKLTEKSKKFEVRKVLELPWVFWAILSFSLFQTSTAIVFSQNATELAEKRFKTDSITAGWYSATLQYAGFFLVPCIGAFIDLLGNRITLLAICGTGVFLAMALINWATDTKGTAAAFGIYAVAFTLGPTTIIDSIRTSMWHSSVFGSAYAVKIATNNASRMNIIVRVITGAIQDADNDSYDHVVIVYAVLAAASVLVSIMLGVLSWWSIDLGNLQWTRKQRRANGELWNERKRAFYEDNGARNKRISMICFGSLVMLILGAWSAYFWGVATGNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAI8</accession>
    <name>A0AAD8XAI8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_587385</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360579.1">
        <property type="nucleotide sequence ID" value="XM_060506033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAI8"/>
    <dbReference type="GeneID" id="85389932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041784470" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="58393" checksum="A7F3B6BD39D372C2" modified="2024-05-29" version="1">MFAAVSLVLAVLLAFATPSAATFQSDCLALTPQTTVLNSTAQKISHVESGTNLTFPEQDASCGRGSQVVRTNLCRVAMNITTSSRSQIVAEVWLPEKWNGRMVTVAGGGLDGCVHTEDLAYATAHGFAAVGTNNGHAGTTGVQFLNNDDVVIDFSYRAIHTGVLAGKSLLKSLYKEKITGSYFLGCSLGGRQGVQAADMFPEDFDGIVAGAPAVDFNNLYSWRAGFYPLTGSVDSKDFIAPAIWKTTIHDEVLKQCDTIDGVQDGIIENPTLCHFEPGTLLCKSDSGDSKCLTSAQVEIVRKIFSPTNYTDGKLFWPAMNPGSEIITADGLYSGSPFALSQNWFRYAIYNDPKWDPATYTLEKDGIFAEKRNPSNIKTYPRDLSAFKKRGGKLLMYHGQQDQQITSFHTPIFYDRLAKGMHLNNTGMDHFARFFRVSGLYHCTTGPGAWLIGQGGSGGNSAVISDSLPFNRTYNVLAAIVDWAEGGIAPDTITGTKFVNDSVGSGVDFQRRHCRYPLRNTYRGEGMDPKVLDSWQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAU4</accession>
    <name>A0AAD8XAU4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">xanthine dehydrogenase</fullName>
            <ecNumber evidence="3">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_46285</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="18">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="18">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360457.1">
        <property type="nucleotide sequence ID" value="XM_060503246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAU4"/>
    <dbReference type="GeneID" id="85387145"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 18" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8 17" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 18" id="KW-0408">Iron</keyword>
    <keyword evidence="11 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 18" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="19">
        <location>
            <begin position="118"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="1151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="681"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="685"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="763"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="795"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="797"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="893"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="962"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1716063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1229" mass="135996" checksum="C72B86F7A1EE7A94" modified="2024-05-29" version="1">MSLYALLRNNDSPSEEDIEEAFDGNLCRCTGYKPILEAAQTFSVERGCGKARTNGGSGCCMENGNGEKKEGGCCMDKAKLDDQPIKRFTPPGFIEYNPDTELIFPPALKKHEMRPLSFGNKRKKWYRPVTLQQLLDIKSVHPAAKIIGGSTETQIEVKFKAAQYPVSVFVGDIAELRQYEFKDDHLEIGGNVVLTDLEHISKVATRHYGDARGQVFEGIYKQLKYFAGRQIRNVGTPAGNLVTASPISDLNPVLWAANAVLVAKSQSEETEIPMSQFFTGYRRTALPQDAIIASIRIPVTAAKNEFFRAYKQAKRKDDDIAIVTGALRIKTDDDGVVTECNLIYGGMAAMTVAAKNTMEYLVGKRIAELETLEGAMNALGTDFDLQFSVPGGMASYRKALAFSFFYRFYHDVIANLGGQSEHMDIEAVDELERGISGGTEDHGAAAAYEQETVGKSKSHVAALKQVTGEAQYIDDIPVAKNELHGCFVLSTKAHAKIKSIDYSPALDMAGVIDYIDKDDVDSPEQNRWGAPHFDELFFAEGEVHTAGQPIAMILATSASRAAEAARAVKIEYEDLPSILTIEEAIEKDSFHNYYREIKNGDTEEAFKNCDHIFTGTARMGGQEHFYLETQASLVVPKLEDGEMEVFSSTQNANETQVFVARMTGVAANKIVVRVKRLGGGFGGKETRSIQLSAPLALAARKTRRPCRYMLTREEDMVTSGQRHPFLGRWKVGVNKDGKIQALDLDVFNNAGWTFDLSAAVCERAMSHSDGCYKIPNVFIRGRLCKTNTMSNTAFRGFGGPQGMFIAETYMEEVADRLGMPVEKFREINFYKPLEPTHFNQPLTDWHVPLMYKQVQDEAKYELRRELIRRFNDGNKWRKRGLAIIPTKFGISFTALFLNQAGALVHIYHDGSVLVAHGGTEMGQGLHTKMTQIAAQALEVPLDNVFISETATNTVANASATAASASSDLNGYAIYNACAQLNERLAPYREKLGPGATMKDLAHAAYFDRVNLSAQGFYKTPEIGYTWGENRGKMFFYFTQGVTAAEVEIDTLTGTWTCLRADIKMDVGQSINPALDYGQIQGAFVQGLGLFTMEESLWLRNGPMAGNLFTRGPGAYKIPGFRDIPQEFNVTLLKDVEWKDLRTIQRSRGVGEPPLFMGSAVFFAIRDALKASRAQYGVAATVGEDREGDGLLRLESPATPERIRLSCEDPIMRRARVLPKEGEKSFFVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBL5</accession>
    <name>A0AAD8XBL5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361734.1">
        <property type="nucleotide sequence ID" value="XM_060510731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBL5"/>
    <dbReference type="GeneID" id="85394630"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17788" checksum="B2FF201F041B6B16" modified="2024-05-29" version="1">MATKYVRDFSSALELRSILGILIEHGADIGVSWMQVIFSTPSVFLLRGKVQPNLEVKNGAGQTPLCKAVCERRYESATLLLDRGASAEPIGRGKRPMDCAIHNKDEQMVKLLWYNGASIKSVGSKDQHGVVMDDKLGGGGKVVDFMKADRQPELSWEVRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBS0</accession>
    <name>A0AAD8XBS0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_44407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360476.1">
        <property type="nucleotide sequence ID" value="XM_060503132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBS0"/>
    <dbReference type="GeneID" id="85387031"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042182724" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11086" checksum="919E2E77E1D863FE" modified="2024-05-29" version="1">MALNASLLTLALLGDLFPTQAPLTEVSLTVGCFLAGGNGGKNGVRKHRTGVEAMTCPRRSPSLGWQAASFAAVASCPLSFYESPDERYWRWQLSRFVFNCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC70</accession>
    <name>A0AAD8XC70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_633548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360971.1">
        <property type="nucleotide sequence ID" value="XM_060509043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC70"/>
    <dbReference type="GeneID" id="85392942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="291" mass="32402" checksum="B2BC17CA35207994" modified="2024-05-29" version="1">MARYPMYIRVRFTPSDNDTETLESLSTFVMELPYGLEIEGKSNRRYNLAAAVRLRTAVSGEADCIRLFDEQGFNVVPDTEGFIYNDLSWEIGAAGHTYYLYCLACDKEWLATNNTRAAHTRDFERPGTLSETWQKGFALMQAAMKKVELEAEQRKAASLGHTQAASEEPIRPSLGSGNDVAGGQSIQPSQRKIKRTAGHDATVTPLNTKRPRRRAPEEIRSTPESPDRQGQSHPQPSDGDQTERQSAQLLGVNQRNLRLRHATSSPDLSTPRDARAPGSVKQETEEADTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCQ0</accession>
    <name>A0AAD8XCQ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_723338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359813.1">
        <property type="nucleotide sequence ID" value="XM_060512551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCQ0"/>
    <dbReference type="GeneID" id="85396449"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="27400" checksum="23DE9E0CB5366A5B" modified="2024-05-29" version="1">MSESSFQRPLRGGCQCGRNSYIIEVPQGTTEKAQVLFHTDSMHIPLATPLAAMIRVPLSWYHSSTHAFYPDERHSAIRRVFESPSNHHPSRRNFCGFCGTPLSYWTERPPTEAGFIHLTLASLRGEDLRDLEDLGLIPEFEEPEEQPAVPTTTTVIGRETQGVPWFEGMIEGTRLGNLRHSQVVDHSKDGKIRVEWEIVEWTEGDDAPDVAPAADGDVNMTTNHPGKRKMNDREDEDAAVDGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD78</accession>
    <name>A0AAD8XD78_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_389494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363474.1">
        <property type="nucleotide sequence ID" value="XM_060502778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD78"/>
    <dbReference type="GeneID" id="85386677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="33277" checksum="4AD4E96FFE609A4F" modified="2024-05-29" version="1">MQPKSEGLPPCCKVAPEALYWNRFSLLFSTNLNHGLISRLTAAPKHRRGRPFRGKDLPPPLAFTNEGSRKRQGQRHYQDAVTPSGVPIPFVGGIPAVRRNSPRFKHVGPRRRSDGAPCSPFRRPNVEHCSVRGPSGHVRLWMASVLRWWCSPGPSDLSGFEEPHNRRSLARRCEETSFRMKHTLFDGIAVADILYYSPSLLPNKLDELLKSPICRRTRWEPQVVAKNGSTAADKCRGAASSLAAGVITRTIPNSSRITSESSGEVHLEAIIGYRAAHHQLPLVTGLRLSPESYQDGFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD91</accession>
    <name>A0AAD8XD91_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362051.1">
        <property type="nucleotide sequence ID" value="XM_060512907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD91"/>
    <dbReference type="GeneID" id="85396805"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17789" checksum="B9971901B77D5104" modified="2024-05-29" version="1">MNATWFKRKTDGPRPTEASSAETCGVRKAPALRYDLRPTEKNVGSRCLVRAMREVGELEEREGRARAVQSQDSIVKQREELGDGHDPLHYSWPGAGPWREGRISLDPFRSSQQSWSTQIVDLRRDLQKFRLVHAGGHDGGEDFGFHPRICGCSCSPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDX3</accession>
    <name>A0AAD8XDX3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_636031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360175.1">
        <property type="nucleotide sequence ID" value="XM_060509224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDX3"/>
    <dbReference type="GeneID" id="85393123"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46681" checksum="E79CB1BA80083774" modified="2024-05-29" version="1">MAPSDKEIEATILAKVREVFKTDIDNLNVNSIRRRVESDLELEDDLLSSGKWKDKSKKLIKELATDLVEGNADPDADVGPPEDEEDAKPKKSGKRQAAEKSPPAKRRKRASAKVEESEASASEEEKPQPKPKKKAAPRKKKEETPVIDSESDEASPAKPKASKPTNGRASKAEESGSDALSSPPDSEDDKVEDKEEKSQDEKVEAKKDDESTEKQPEASADKKAEDPADDTTSELSDVIDEPPKPKRKKKEAGAGSKTKAKAPKQKKAPAAPENPDDAEIKKLQSHLVKCGIRKIWGFELKQYGDDTKAKMRHLRGMLKDIGMDGRFSEAKAKEIKERRELEADLEAVQEMNANWGAEGRSSRSKARGQPAPKKAVKDDVSDDENVKDDDDEDDEDEGSHIPSRARGKARADLAFLGDDDEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFN7</accession>
    <name>A0AAD8XFN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protein 14 C-terminal Fig4p binding-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_719127</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365662.1">
        <property type="nucleotide sequence ID" value="XM_060512147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFN7"/>
    <dbReference type="GeneID" id="85396045"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="581"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="812"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="834"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="853"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="891" mass="99514" checksum="F6B71983B346C5B1" modified="2024-05-29" version="1">MEVSIQRALNDKLYDKRKVGALELERVIRELVVTRDYPRVQAILEQLCNEFAYAVHQPHARNGGLIGLAAAAIALGHELPRYLEKIVPPVLACFTDQDARVRYYACEAMYNIAKVAKGEILIYFNDIFDALCKLGADSELSVKNGAELLDRLIKDIVSESAASYVSVLEGELDQQELSDKDELEERAAPPTAFSLRRFIPLLQERIWVINPFTRQFLVGWITLLDSIPDLELVTFLPDFLGGLLRFLSDPNRDVHVATRACLDKFLSEIKRISRIKKGIAESKKSREGGKRKREESVDSGSLQIGPEEGDEVDSQSDDDDSSGEEDWVPGQDVQINYRKILEILTATLDSPLEEDSLLESLRWIVEFLDICPEEVLPFTPKVLAHMLPAMASGVESIRQAAARVNAGLMDYVVSLSDEPEIGGNSQSMSRIPVSGERQEGPSSARASLSSSRDLEMRSPTPAQGHNRSLSTPVAPLVNNHPQVDLDYAAAVNALTLLFLNDHEATRVAALTWLIMLHRKAPRKVLAFNDGTFPALLKTLSDPAETVVTKDLQLLSQISRNSEDDYFSNFMVNLLQLFATDRKLLETRGNLIIRQLCVSLSAERIYRTLADCIEKEEDVEFASIMVQNLNNNLITAPELSELRKRLRNLESKDGQTFFVALFRSWCHNAVATFSLCLLAQAYEQAYNLLQIFAELEMTVNILIQIDKLVQLIESPVFTYLRLQLLEPEKFPHLYKCLYGLLMLLPQSSAFAALKNRLNAVSSIGYLHIAPKVNPPSTTSSSYDRPNRLKSREDSIIRWNELLEKFRTVQERARRAQRHSGDVEEGRGSLGVADLRLGESLDSKGPKEARNTSGPPVPVKDPPPPAPPAAKRSGLGMRQIRNLGGAVRGKRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFZ0</accession>
    <name>A0AAD8XFZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_718456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366519.1">
        <property type="nucleotide sequence ID" value="XM_060512076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFZ0"/>
    <dbReference type="GeneID" id="85395974"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="8"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="34854" checksum="13EA45127068B707" modified="2024-05-29" version="1">MKAYQFSTPAKGLEYCELPIPVPAKDQLLVQIKATGLCHTDCNIISGLDNTFFWNRPITLGHEIAGVVVGCGPEVSKFAAGDKVVSVITAKHPVEIGDVVKSPGIGIDGGFAEYVLLYESKTLHIPDGVSFAQAAVATDAVATAYHAVATEGQIQKSSKVAIIGLGGLGLSAVQIASHRGAKVYGVDLHRRKYPAALLSGAYCCGRSLDDFPGVKFDIVFDFAGVGITTAAAAKAVKAGGKVVLVGLTKKEATIDTHNFVALGVHLVGSVGSSMDEVEMALKMVAKKEITPAIEEVAFGNLKDELHRLERGETVGRLYADPSRLVERVVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHN7</accession>
    <name>A0AAD8XHN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_752058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365123.1">
        <property type="nucleotide sequence ID" value="XM_060514143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHN7"/>
    <dbReference type="GeneID" id="85398041"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203:SF86">
        <property type="entry name" value="PROTEASOME 26S SUBUNIT, NON-ATPASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="410" mass="45531" checksum="6BBC0CF8FC7C5B29" modified="2024-05-29" version="1">MSSTIPHGEFPAEIWLQICIYLDSCTVAALAQVSIKLHTNLQEEVYLAAIRDGITDIITRSAATGNLVTLQRIASHGADMNKVYSFDAPQCLEDWVKVEYWKEWKRREVPSDDGVKVALSKACFATPLHLAAKGGHYDTVQWLLDQHSVDMEMPARFLCQCIPPGTFQVPGCHLMGHAVPAWTPLHTAICNHKVSVARPLLSRGAPSRKVSVSHSSPNYPRVNQVFASAYRGLDPTKYPGPAVMVSALQSAAFSGNWPIIKELVQCMGVDVDEVVVESGATPLYYAITARNELSVALLRRLGADPEQPFTPEWRSVHYNNDFEYALVMEETDPTPNISELFSSEVATDIFKFSSNVAKSNAARYLFSESEGAWYCPSGTEGKIVSRLRQSLSTARSEYWARIIQPLWHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI30</accession>
    <name>A0AAD8XI30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_750190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the YPI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367226.1">
        <property type="nucleotide sequence ID" value="XM_060513893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI30"/>
    <dbReference type="GeneID" id="85397791"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0650">Protein phosphatase inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="19361" checksum="656F424FF8148220" modified="2024-05-29" version="1">MAGLQDRLPQRSAPGPSQTQTETQSRTGTQAILRLRGAHAPSRQSVRWAEDVVDNEGLGRKSSKVCCIYHRPKGVDESSDESSSDSSDDSDDSDADTNGGRRRVPSGDHKGKGKGKKSGKRGDHDHDCDDHDHDHSGHGHGRKAGREGSEKRRPSPNAYERVPKPPKPKDEGTGGSPAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI65</accession>
    <name>A0AAD8XI65_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spindle pole body interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_649640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367346.1">
        <property type="nucleotide sequence ID" value="XM_060510297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI65"/>
    <dbReference type="GeneID" id="85394196"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="121"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="837" mass="94050" checksum="F87045D286DBC18E" modified="2024-05-29" version="1">MASTQAALPFLTRNYSNTQTQYPPPPNGPWPSRRTSLSSFPASRSPSSMSNTSRPSRSPQPPPIAETDRSSNPSSKSKTPSTGVSSQHSSLSAPRRYNPDAHPPRKLRSQYPRGSTENHVEYILVASFDIDRGPVMEHQYPVSITGDEHMLAELMLPDQAHVRNQDWTIFFLHKDTSQEEEDEERKAKEARKKRRRRLRNRAAGIVDEEDDGEDLDEEDGDLDDLDEYDDEDSDDGEPEGGEGPPLIYVLNLVNTKQDKTVKRGAVVKAMAICTRHPFLHIYKPLLLLALDEYFKAPVPETLAMLYDAVNAMDLSLMPKLSLLERHLLLASDNKDLFVEKFEQMIQMRIAEDRGEHLSDQPFDASRDPPKLPGVSRAGTKAHVEGASQFSVPRDTHEFESRVMYKGIPIPIKVPVAVMPETVGDFSLIKLIQKFSEPQGKAPQPFPLHPQLTTNGPHTHPIIVLVNALLTQKRVIFLGHNMPSGEVAEAVLAACALASGGTLRGFTRHAFPYTDLTKIDDLLNVPGFIAGVTNPTFELHPEWWDVLCDLPTGRVKISSKIDSAPVTEGMVYFQQQNPSYAGLVGGTSKVAAESDLTGDAAFMQDILRSIAARHGERVIRAKWRDWVIKFTRIAAAFEESVYGASALYIGGDELEMGPVGVNGHGYVWPDEQSKHKELAGNVTRIEGWRNTRSYYSFIQDLALLYTVRPLKGLDLHHMHDRLRTQRLNPMQSKEIYAAFHKYVHSYDEICLLLSVAPESHAGLFYVALGLFHKDREVRLKTADLLERIGEHEAGQHWWKALSRFEKLAYNRIRKEMDAEMRAKLEKEGLSPEVEKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIG0</accession>
    <name>A0AAD8XIG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_649509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367706.1">
        <property type="nucleotide sequence ID" value="XM_060510288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIG0"/>
    <dbReference type="GeneID" id="85394187"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="125" mass="13732" checksum="ED992AD51860D7F7" modified="2024-05-29" version="1">MLSAPQLAPSLVRRASSARVPHAFRFSANLFGLSLARKLAIKVLRTSLTIKVLTLTFRAGPHFPFCASACARPCACRPRLTPVPLWSTVPGSFQVLSAKLVFCPRYLLLGITVNLEKVNRQNSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIQ2</accession>
    <name>A0AAD8XIQ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_752218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364885.1">
        <property type="nucleotide sequence ID" value="XM_060514166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIQ2"/>
    <dbReference type="GeneID" id="85398064"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="12"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="36223" checksum="211DE6412E74E507" modified="2024-05-29" version="1">MAGTIRALVSQGDKTAKVQEVPKPHPGSGEILVKISAVAQNPTDWKATAGAPAGRTVGCDFAGTVADPNGSSLKEGQRVAGFVMGTSDDPPRGVFAQYAVIESSLVFPVPESVTDSQAAVIPLAFATAVQALFQRLGLPEPTSPSKGAIPVLINGGTGSVGLYAIQLAKKAGLYVIATGGKKNHALLKSLGADVAIDYRDADWIEQVKKAAKNGLKHVFDAISEVETTKAVATALSPEGGHVVCILPRKAKEVGAPEGVKVESTLVYSVFGRALTYGSFDNIDGEKPEDKKFWEKYLGLLPKWLEDGSIKPNPQKEFGGLDDINKGFELQAKGGVSAEKLVYKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJG1</accession>
    <name>A0AAD8XJG1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase eta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_740095</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366535.1">
        <property type="nucleotide sequence ID" value="XM_060513056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJG1"/>
    <dbReference type="GeneID" id="85396954"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009314">
        <property type="term" value="P:response to radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000008">
        <property type="entry name" value="DNA polymerase eta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041298">
        <property type="entry name" value="UBZ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18439">
        <property type="entry name" value="zf_UBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51907">
        <property type="entry name" value="ZF_UBZ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UmuC" evidence="12">
        <location>
            <begin position="39"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="UBZ3-type" evidence="13">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1726480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="552" mass="61781" checksum="0F53A21971A8CB5D" modified="2024-05-29" version="1">MSDDSFTFPTDPTSAESQFTQQDLQLLAQSSPESPLRVVALVDYDSFYAQYESVRLGLPPSKPLAVRQWNAIIALNYPAKDRGLKRTISVEEARRLCPDIVLQHVPTWREGDDCWRYRADVLDNLTTDKASLDPYRDMSRRTMKLVRRILPATPAPTIERAGVDEFYVDLSAQVYQILTERFPGLGSLSNSPEKTLPLPPVDTSLNWKSDKVMDLPNTRDPEYILDWDDVVLSIGASIIRNIRKEIKAELELTTSAGISHNKMLAKVASRMNKPFGQTIIRRKCIPTIMPTLKVTSLSGLARQLGQKVVKTFGSDGIRDLLQVSLAEMRSELGSQDGQWVYRAIRGDETGPVRPRSEVQSLLAAKTFVPKAENLQQASKWLRIFAADLESRLRDLDLDSEVPRRPRTIAVQHHIRGRFGPTRSKQAPIPPHVDINRETIFNMLHGLLKDLTDHGESWPCLGISVSMSNLESGVPTSDPGQHSKRVHVANDALCSASGRLATTSTSARAVQGGPRDEQGQQYLCPKCDEPVQPEDVLEHLDWHVAMEIQNQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJN9</accession>
    <name>A0AAD8XJN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor hoxa13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_573272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367105.1">
        <property type="nucleotide sequence ID" value="XM_060504604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJN9"/>
    <dbReference type="GeneID" id="85388503"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23242">
        <property type="entry name" value="TRANSCRIPTION FACTOR HOXA13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23242:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR HOXA13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1168" mass="123709" checksum="C0EB123A6F687422" modified="2024-05-29" version="1">MEASSGYASNGYPKAPNGKMNGKMNGQAVTIKRRTTPTRGPSFFRRSFNILARILTWYSLISILFRCPANLEACDESSPKICKPYFQLKQAVLPHVEPYYETYAAPYIEKAAPYYDLANERVFLPTKAYATKYGAPRLQQAQSYGQAQWEKNIQPQLSVYQKLAQDKYDQTVAPHVAKAYTTVGPYYDIARTSALQTYHDVLFPSYQFVQPYAAQGYAVASQFTTETAVPSAYWAWNKTYSFLDATVWPQFRVLYIENVEPQLARIGQRLGRYKNKTKGSLENVSESGSAKASSFTKPAASTASSLSSSASSVISSATEKASTAIESAHIPDASEVAQHDHSEQVHAPPPGENESDIRKIARETVIEDLSSWQAKFAKAADEGASEIEDRVEEISQRVIKERAHGQGRTLVSELQDAAKSEVDALQKQIIKLVQKSVDAPESAQDELLASVRKAGLNVKEKARKIRAWKAEYEAEIESSVSEAADTHFKILESIRDLALQRIGMKWAWMDGITYKDWAKYHELKDRFAEWMSDLKKLIITHPGLEAAREASNEVEDSGMAVAQSAAQELARLKQVGLWKLAAKDSSDNFDSETVRLAAEEADRVREAEVAAAEAAKVAEASASEAAATASEATSTPEEDPLESAASVIEDESPASDLNSAGAASSISSVAGEVKESVSSAIPAVSSAVSESVSSAASQVSSAVSGSSSSVASEQPDLASTIIPGQDQTYVIDTDGTSPAGDEENAVPGEKLEEEIISESVEDKPVAAATESVKPAFLGAAAQSVPSRVPILDDDEDEESISSRAQEAYSAAVSKASEQYSSASAAISIKIYGTPQPTAEKLVASASGIYAAAIASASAKYDEAVKAASNALYGTVAPKPTPSYDWSSVKAIAMQRLNEGRLAAEQQYESAKIKLGLATATPTSTVDKLLEQAKYNYYAGLGVAHARYSEFLAAASAAMSSATATSTPTNIAGTASSAASSAASVATRSADAVASGAQKEAMAVASAVSDGFSAAASIVSDSVSAGVQEVVDAAQAIEKGVSDTWEAVVSRASVQIYGKPTPTAWYDSAYSGAGQYASQATAAVVESLAAAQVQAAKQYEDMSKLVSELLVGKEPTVSESVLARLQAAYSTGIASAASIASAASATVSSAASAVTDAVKETVQHVRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJV8</accession>
    <name>A0AAD8XJV8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotransferase</fullName>
            <ecNumber evidence="8">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_571726</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367960.1">
        <property type="nucleotide sequence ID" value="XM_060504433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJV8"/>
    <dbReference type="GeneID" id="85388332"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="10">
        <location>
            <begin position="229"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="548" mass="60045" checksum="B9B2D53534F93E81" modified="2024-05-29" version="1">MALEAETKRVVDQFELSDAYINRAVSEFLGQMQTGLEKDGSSMSQIPTYVTGVPNGTEKGLYLAVDLGGTNFRVCSVQLNGDTTFNLTYSKVAIPKELMVAKTAEELFSFLAKQIELFLREHHAEHFEQHIRRRQTYSAPEGYRDEHVFRLGFTFSFPVQQLGINKGNLIRWTKGFDIPDAVGKDVCALLQVEIDKLHLPVRVAALVNDTVGTLMARSYTSTGKSGSILGAIFGTGTNGAYLEKLSNIKKPIVGEFESATGEMVVNTEWGSFDNQLNVLPNTPWDDALDKASVNPGIQMFEKRVSGMFLGEIVRLTILDMLKDEKLSLFKDQNSSFNDWKSTTSIGAQSGMFKQWGLDSSIMSVAAADNTPELSTLRQQLESEMLVYSPSLEDAQAFKAVAGSVGRRAARLSAVAIGAIVLQSGKLDDETEEVIDVGVDGSLVEHYPFFRDMIYEALRSIESIGPKGADKIRIGIAKDGSGVGAALIALVAAGMEKEGDVLTEFRQNVKRELDSIPEQRKLLVTRVAETKGDVDRDELPAAMHCETVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKD8</accession>
    <name>A0AAD8XKD8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_569328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369041.1">
        <property type="nucleotide sequence ID" value="XM_060504178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKD8"/>
    <dbReference type="GeneID" id="85388077"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001425">
        <property type="entry name" value="Dynamin GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF215">
        <property type="entry name" value="DYNAMIN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="33"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="649"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="737" mass="82908" checksum="8CD360AC45DB5D2B" modified="2024-05-29" version="1">MAPAHSKTQATGLGNRNLLDKIDKLRELGISRQIALPQLVVVGDQSSGKSSVLESLTGYYFPRSVGLCTRHATEIVCRREHTPSIVVTIQPADDTSARADLARSFQRELKELKGQAFADVLREAAELMGLKSAKNSEGIAFSKDVLRVEICGPNEEHLTIIDVPGVSTAIDVALTKSMVKDYIKDSRTIILAVIPCNVDVATQTILTYAAEANPDGKRTLGVLTKPDLVSENATREAAMDLVRGKRRDIQLGYYVVKNRGADDSSSSKEDRDAYEKTFFAEEPWSRLDKSRLGIPALRMRLRELLMDRTKSEFPKVRREINERLAEAKTKLKDLGQPRSTADEQRAYLGKIVSRFTELKNFGLDAYYTGDPVFDTRPELRLATRIREMNTAFASMFFKKAHTRDFDDLVEKKSDDTEDWQSHDNDDDDDSPLKVSSDDDEDDSKEDEDATRDDLYRIAFPVPSDEYGELDAILSDPCRCPAPLKHSILKHLEQLYLRSRGFEMGTVSKPHMLPTAFKEQSKKWESITLAHVSNAILVVHHFIHGVVKESCSDEQVFDALWSSILENLIGRYQVAMDQAKLLIHVEREGRSITYNPAFDRALNKIKAARSAKKFENLKVSLNLEYAPADYVRYEDLKKQITHEKGTSATSCVIHDVLQSYYEVASARFSDMICAQVVDYFLLGAEDGPLSVLSANRIFKMTAEQLEMVAGEDALSKSAREILKNDIMLFEQGRKVLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLE5</accession>
    <name>A0AAD8XLE5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369608.1">
        <property type="nucleotide sequence ID" value="XM_060504057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLE5"/>
    <dbReference type="GeneID" id="85387956"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000096">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="908" mass="100005" checksum="2CC1FB4ECE335ADC" modified="2024-05-29" version="1">MGGVDMSRDYYADLELPADADTNEIKKQFRKLALKYHPDRNPGREAEVNSRFQVIQSAHEILTDPQQRAKYDAGRTRSRYPTASGVRGNPWQNAGANFPPPPRRNATARNPPPPPPASGASRYRNFASGAAPTAKAQTRDDSEAKRNAWHAFENMKGRASQSQPKPAKAPETPKRPVPRTPSQKQRAEASFGRKPGYTPHSPVPADEPPVNSSNYSTSSRHTNIFADNARRQQEAGVPDPLAQFRDSDSRQSTPYMSHGGEKLNPFDGISVGRAKSTRESPRPPQESYGPNLSPGSARQRAQSVPRQARTEPSSPRTSTSTPQEDRPNTATATASNSPKDPFRSRASARYTPPNTATGPGPNNAQAKATASQNLNGAGNIHTAQGSSMYGTYFPPGSFPPFAVPNLRRKSAAEARARYATQHPLPEQSSNAGLHDSPSPSGDRSRRSDSLTPFERKQGELLSKLVKRQAPDLTPLSRDKRHTIDTHHDVTPNQADQKITNSFNFPIDDDTFARTAAPEQPTFSRRSTEEIDTSFVNGDGPDAWKFSAGSPIQDQAAKVRSQSGSRVGRRSPIKRPSLRHQKDMSGQPAGSPSAEGKFDAQDWTQQIGAQNFVPHKTHSTSTSPTRISRVNSRKTKVKPTAGGNAGLVNDDYDSDEETEWRGRKSMAEPIGANSPNAMDIDPPQTGTSQKRDHSNSARNIPVEPSRPEWRPGNGLQENGPKLPARKPEFNPNNAGSEDSEEFRASLADLKNVAPFAQNSSGLGSLNDLKMSLPFESQPSGRAPIEKEKKPSLDFPVIPQVPRPPPTFAVNLKPTGGAWQKYTQDFQSYVLRWEIFNAQVIEHFNARKANIADLRARKGYSFLVSRGDDEIHEYLEWMAQDKEVRRKWAVACEDHEARIREFMVYKGKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLI2</accession>
    <name>A0AAD8XLI2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369640.1">
        <property type="nucleotide sequence ID" value="XM_060504060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLI2"/>
    <dbReference type="GeneID" id="85387959"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12432">
        <property type="entry name" value="RRM_ACINU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034257">
        <property type="entry name" value="Acinus_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="663" mass="72422" checksum="0C84ED03FB39BF35" modified="2024-05-29" version="1">MNWSKQTVVQLKAELKRRGLATAGLKQELVERLTTSDEAAEEEVQEDVQEEAQEEEEASPEPEPQPAEPAEALTEPAPINTTAEDVADTENTIAQAVVASSEPKMEQSALKPATQDTETTIPESIAAANPTPPAPAEMAQDAQKRKRRSQSPAESSESITRKRIKADQGRIEADKADEAPSSESTSVAGVINQIKEGVKDVLKESLEGGSGLLEDVAKEAKDTSKDVEELAESHPIEQDLPTTEANAEEDTEMQDELNGKVDAVSAADPEHRQASVHGQEHPTDGPVTDQERHEIAPADDNDAMEYERTVQPAIHPATRALYIKNLMRPLKESTVHDRLVELSTPSGAEPNSDDVEDVYLDSIKSHAFAVFRTTTLASRVRNALHDVTWPDESNRKPLSVDFVPPEKVRDWIHEEEAEGKSNRSARFAVRYDIEDDGYVTARLVSGNGVASAEPTRGAPAGPAVKDVNAIPLGPRGGRGFEGAPLGPRGDSQRGPGSRPPRLIENFPGGPVQTTRAHPPVSFQAVSDDLVSRRLRNMRSYYTKDIDRDMGPETEINRYIFEEGDKFVDRGHENFVGIRPPHREAERRRQMAGGGPPPRGPPPPGRGGRRSGGNGRRGPRMVSDRYLPGINESGPYRQGDRGNFGGSRPDGGRRFRSDDRGSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMH0</accession>
    <name>A0AAD8XMH0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pre-mRNA-splicing factor 38B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_421325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370094.1">
        <property type="nucleotide sequence ID" value="XM_060502984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMH0"/>
    <dbReference type="GeneID" id="85386883"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40132:SF1">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="45998" checksum="1C08C1C6533CC3DC" modified="2024-05-29" version="1">MSSHDMITDDYVADLLAKEAVMDRADKKPANMPKPNTRFLRHIIKDTNTHNKNLLAKEAAESRARLKDLEHAEEKERRRKAGPQDIRKRQMGDILSILGDRKDRSRPSRSGTSKEKLHKEEDSLPRRAHRKERRSESPERESGRKHRRSRRDESDSERDDRRRHKSDRRRSRSPDEKHRRHRHRSPIEDREIASKSRRSEREKRRDEEGQDLMSKSHRSRRDRSRERPQSGFSIKGSSRRQRDGGRAREQEPQTTASDSDPLDEFIGPEPPQQVRSRGRGTASGASGIDKRFEADYNPKTDVEMADDDKHPGENWDDAVEAFRDRQKWRQNQEERMRAAGYTDVMLKKWREGGTADEQKDERDVRWAKAGEKREWDRGKEDGLSGLFSEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM8</accession>
    <name>A0AAD8XMM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370149.1">
        <property type="nucleotide sequence ID" value="XM_060510058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMM8"/>
    <dbReference type="GeneID" id="85393957"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042296389" evidence="1">
        <location>
            <begin position="16"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="18917" checksum="A806B15C6C220A39" modified="2024-05-29" version="1">MKLALLLSTVTAVSAWSVTFHDHDQCAGGSTFHYGGGSNTGTEHLAQCFTMTSINRSFANYDAKSVNIVFGGCTIDIFTDRLTRPGLAGCVASISNPTNWQRINQVQDGCVQPSTLRHAKRTTCFKLLDYFSAQQLRKKLLKDWSELFSSLSNFYALNVPWSFASPQTDCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPZ6</accession>
    <name>A0AAD8XPZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_163002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371610.1">
        <property type="nucleotide sequence ID" value="XM_060501412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPZ6"/>
    <dbReference type="GeneID" id="85385311"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="131" mass="14865" checksum="6D02D0531F292BC0" modified="2024-05-29" version="1">MMEFAWSRRRDTIIVLLVGPLSSILPVVPVKPVLPCAGRGRDPPTAESMEHESQVDQEHGPSRLIKLTTDCRRIIEAPPLLLTAQRHKCRVRKTYASQKISSPIPLYSTSRVESEYLDFDLHTHRPDTPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRF8</accession>
    <name>A0AAD8XRF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EC51a protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372037.1">
        <property type="nucleotide sequence ID" value="XM_060513006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRF8"/>
    <dbReference type="GeneID" id="85396904"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042180029" evidence="1">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="23065" checksum="24C450C2802F6BA8" modified="2024-05-29" version="1">MKFLHILSYCVIASGLAVPNTAPEAEISVRDPPQTVPVRTDTFSSAGIFSRDQSKAWREAEKVVGRPLQHGKVYYFMSCNPAYRNHYYTQDVYLKYVVDQTDCVHVGLVIGKTSKWFKKFEAEYLHVRVDEDNAPDEWYQSRHDWDGPIIDQRITFGGMTDSTSISKLWKAGKQWVKDAGSQMDADWNCLQYYRHLVSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYQ6</accession>
    <name>A0AAD9CYQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TAP42-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_607345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368943.1">
        <property type="nucleotide sequence ID" value="XM_060507425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYQ6"/>
    <dbReference type="GeneID" id="85391324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051721">
        <property type="term" value="F:protein phosphatase 2A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035303">
        <property type="term" value="P:regulation of dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.540">
        <property type="entry name" value="TAP42-like family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038511">
        <property type="entry name" value="TAP42/TAP46-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007304">
        <property type="entry name" value="TAP46-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933:SF9">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04177">
        <property type="entry name" value="TAP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="488" mass="54782" checksum="EDF2278D98BF8117" modified="2024-05-29" version="1">MQIATQPKDLERRNLTFGASSRWPLLSAKRRTVAVDSKLATNPSNATAYDTLIVAAAWFYYISCRATSLPFEAFLLVFPATSRNSHSLPTPPPLHSSPLLTKQQTTPSTNTSQQPTTSIRTATMADEDQPQTLKTVFTSAERKRLTLENSYEASSPTYLDDLQTAIAEYETCLDLVSRAALFSSNESLEDLSTSSLPYLLITYHLAELHQKLPSRRPIERRVALERARESYETFLGALDSYDLLTDTNKMLYERYTDEPLAFSTLGTNDPAKRRDAKIANFKSEKALKDRLEALRRNPRYQNEDGDDEVARDLHLAHVAYSAHMAFQGLEGINRELEVLAQATVPLMPSPTSVEEDERRRTEDRGAAGYTERLEPPRRLQSMFGQGGPILSTEGKPLQPFTLVGNRQQMTKDVFRPGHNLPTMSIDEYLDEEARRGGIIEGGGDASWHRPEPNEDDFDKADEETMKARAWDEFVEANPKGSGNTLNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0M9</accession>
    <name>A0AAD9D0M9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PUL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_567601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369992.1">
        <property type="nucleotide sequence ID" value="XM_060503969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0M9"/>
    <dbReference type="GeneID" id="85387868"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="5">
        <location>
            <begin position="299"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="580" mass="63516" checksum="0499760EA9DDEB22" modified="2024-05-29" version="1">MDVHLLTYDLSRGLARQMSQGMLGFHLDAIYHTSIQLNGREYVYDGGIVDITPGTSHLGQPMERIFLGKTELPMEVIEEFLDSLRPIFTAEAYDLWRHNCNNFSDSFSQFLLGKGIPEHIIKMPDAVLSSPMGRMLMPQLNQVINSNRQNGSILGIQNNSTPPGYGSAAQSTKPQSNIRIVSSSQELDAALESARKSCAVVLFTSATCPPCRAISPIFDEVSAEAGSKATFIKVDVAQLTPLPGKNYPRATPTFITYLHGEKENEWAGADPAALRGNVQLLLQMTWPRHPHESLKLPSFSNPNAKPVLFSKVPPLAKLLGKMGSAADEPAVQATKQFIEARDKQGAAAAVLPNLGEFSGFLQRSVQTLHVEVLFTIVDLFRCALVDARFSGYFAEEKGHTAVLAILRLVNSHSDCPYALRLVTLQMACNFFSTPLFPEEILRNETLRAPVIQLISSSFLDDSHNNVRVSASSLMFNLALFSNKARREKFGDVLPDGDAVELAASVLEAIGQEESSPEALQGMLLALGNLIYCTPSDSEVSDLLRAMDAEDTILAKKKQFPNEMIIVEVGSELLGKGLRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1U4</accession>
    <name>A0AAD9D1U4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium/hydrogen exchanger family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_427507</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370265.1">
        <property type="nucleotide sequence ID" value="XM_060503021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1U4"/>
    <dbReference type="GeneID" id="85386920"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="9">
        <location>
            <begin position="59"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="868" mass="93192" checksum="ABC221540D62ACFA" modified="2024-05-29" version="1">MSSITSMLSATATSSAAPTSTGGNRAPSQGGVIEGANPSHYNPKDPITIFIIQAGLIIIVCHLLHWPLSKIRQPRVIAEVIGGIVLGPSVLGRIPGFRAAIFPTESIPNLTLVANLGLVLYLFLIGLETDVRFLVSNWRVATSVAFAGLALPFAFGCALAWGLYNQFSGDEGVMHIDFPIYMLFIGVAIAITAFPVLCRILTELKLLDTSVGVIVLSAGVANDVVGWILLALCVALANAGTGLSALWILLACVGYMLFLFYLVRPALVWLLRRTGNIENGPSQSMIALILLIALASAFFTGIIGVHAIFGGFMVGLILPRENGFAIKVTEKLEDLIGALFLPLYFTLSGLNTNLGLLDSGIAWGYVIAVTFTAFLTKVIGASLAARLNGLVWRESFSIGALMSCKGLVELIVLNIGLQARILSTRTFTIFVVMALLTTFATTPLTSFLYPRWYQKKLEAWKRGEIDWDTGEPISSHGGSTDDHEFTKPTNDRVQRLLVYLRLDNMPALLNLVSLFGKQSGSGDQFVESDEKGGMKSDTVALSSSNGIRAVRAHGFRLLHLTDRDSSVMTVSQVDDFSRNDPVVNIFRTVGQLIRVAVSGEVSIMPETRFAEALLSKSSDISSDLLLVPWSESGSLVDTQVLSADGSNKLGSTYTGFAKSILDSPEHNIGIFFPKGSATQPTSDGSSDRKRLSRAYSFSDIHHDIPTIPVTNKSHQIFMPYFGGKDDKLALKLVLQLCEKHNAQATVVHFTGTAEGDSQSHEGDYFGFVSTHVPANVAPRIKFETSSSSNALEAASSYAASGVRTDTREVTWHNLVVLGRRSAVKAIEGKASARVSEDIKDCLGIAAGVLITAGVKADLLVVQAKSSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D205</accession>
    <name>A0AAD9D205_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CMR1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_746799</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370982.1">
        <property type="nucleotide sequence ID" value="XM_060513319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D205"/>
    <dbReference type="GeneID" id="85397217"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="149"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="855"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="856"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="984" mass="109458" checksum="37D934854F1F06CE" modified="2024-05-29" version="1">MVFCAYCGKSFTRKEHLERHIPSHTNVKPHRCSACQLSFARRDLLQRHHSTYHEARDPMEPLPGGVPTVAGRTPIACQNCANAKTGCDKRVPCSRCAEKNLPCAARFARRSSKAAVRAAQASAAFQQQMMPTVPQPSQPAQPVAFMDLDPTMPKQDSPGKMSTGSPIATMDPRMMEGPVKKSSPAQSHPSSDDFPSPHSRVDGLDEFMQLNSDFITPDTNYQDMMVWPEYPLELDMYSSQLPMSRPDMSMPSFTELSDMSSSSASEPMTASSSRGSIHTRSTSIMSTADFDTTMKPAEQTLGMPSESAIPEFEVVIAAEDSWPLARCNPPIYSGTCPRTAIVHLECLERKSKEDGTWSSLEKYLENVDWDTTDASVVPLTSRTRDRMLAITQSFLQKALDIHRSGLSNGYSKTGYATPSEFNFIVLPPTKILEYFLRSYVRSLQYYYPLIVAGCVDPNEMLLNNQASTLLLLLMIAQGAAAVPMAEARYLAAGLTETCRISLFDIIEKDVELSADPVALRCALLFTLQGAWSGDKWLMDISMGQRGMYLSMLKHAGMLEPQPSMIPTLNSTTSTELQWRAWLHREMQNRLVYNWVMCDQELSLFHDTPPQLAITDLQCPLPSPEALWLASNSEQWFANVQNLYGCTANVNPQLLSSPSLTPSLCELFQDFLHDNLSRRQAGLSPQQLRLLLHPLQSLLCHLRQMLSCFSDVLSTRRATSRTVTKSSTMLRLEEVQALLQKWYELTMLYYKSNPNCTTTRCNLVLYHLISLNAVTNFPEIERLARRDGFDGSYWELSLRHKRCVYNREEAIFHCGQVLRLLRSMPADRRPCWWAAGVYRATLILWADSVARLDPNFQKAQQAQQQSSSPSSQHQGQSPEHLSGAGASNAAAGGQHGSGNVVAIDQVTPEDPSVISYLWSGGDGIAVLTRRDGTTLGLDKPAEVINYGIMAIEEGVTCRVGDGIRRKLITLNNNWNVNGLANTATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D241</accession>
    <name>A0AAD9D241_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PQ loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370311.1">
        <property type="nucleotide sequence ID" value="XM_060513444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D241"/>
    <dbReference type="GeneID" id="85397342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052241">
        <property type="entry name" value="SLC66/Scramblase_ANY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856:SF9">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14856">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32981" checksum="4BE9AFDFEA45CDFC" modified="2024-05-29" version="1">MRWLTSFAGYLAPIFLIMSPVLSYSDQALSMHKNKSSAGFSLDIPLIMLVASLLKIFYWPGARFDTALLIQALLMIVMQVILLKIALDHRLPPSAKGGEAATPFANVNDGPVFGAQRPYHFWQWRSPKPYWQFLLYLFIGLTVCELLLAPVRPVYQTYSMLIGYIGLSVEATLPLPQIFSNSRSKSCKGFRFSVLASWLIGDAMKMFWFFTSTTEIPWAFKLCGMFQAGCDSFLGVQYLMYGDGEKGEIKEHPMSQYPQYPNGVYKPPLPEHVSGRSSPAGRRTSSPFGKELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2M9</accession>
    <name>A0AAD9D2M9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">aromatic-amino-acid transaminase</fullName>
            <ecNumber evidence="9">2.6.1.57</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_601008</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an aromatic L-alpha-amino acid + 2-oxoglutarate = an aromatic oxo-acid + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:17533"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:73309"/>
            <dbReference type="ChEBI" id="CHEBI:84824"/>
            <dbReference type="EC" id="2.6.1.57"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.57" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370940.1">
        <property type="nucleotide sequence ID" value="XM_060507070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2M9"/>
    <dbReference type="GeneID" id="85390969"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008793">
        <property type="term" value="F:aromatic-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000074">
        <property type="entry name" value="Aromatic amino acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="254"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="66984" checksum="CB07084538F35A0C" modified="2024-05-29" version="1">MYSRAARRGLNGSVCRASSEPLSAAAAPPRTPSRLTDLRRRSRERAPVIWEPVASQRPFHSKSSDRSVADAVPVERKATFEKRQQPSPFDGVRERRAKAGKLIAGVAAASDSDMFKAPAIGKPKSKRWDHHLSKESLSRHPCSLKQAARHLKKPGLISLGGGLPSSAYFPFASLSVRVPTAPHFSEADTIGAHGQDITVGKYDVRDDPEGRAEYDLSIALNYTQSTGSAQMMRFVTEHTELVYNPPYADWQCCQTVGSTAALEQTLRMFCDKDRKDAVLTEEYSFSTALETIAPLGVKAVGVPVDAEGLLPDAMDEMLSAWDPAARGGHRKPHLLYTVPSGQNPTGATQSAARRRAIYAVAQKHDLYIIEDEPYYFLQMQPYAGPDASAPAAPPPSSVDEFLGTLIPSLLSMDTDGRVLRMDSFSKVLVPGSRLGWVTASAQVIERFIRHAEVANQGPSGFSQVAVWKLLDETWGHEGYLQWLMNLRMEYTQRRDWLLAACERHLPRDIVSWTPPAAGMFLWLQIDHTAHPDSNSSRPLLEIEEEIFNSCIEKGVLCARGSWFRTEQDTPLKDLFFRATFASASEQDMDKAIQRLGAAIKESFCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D381</accession>
    <name>A0AAD9D381_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_715229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371450.1">
        <property type="nucleotide sequence ID" value="XM_060511724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D381"/>
    <dbReference type="GeneID" id="85395622"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="285"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="68228" checksum="2928E491D90DCED4" modified="2024-05-29" version="1">MEIKDPPEVDDFEHLRMNAKRLGNRKGQIPHDHPPTSMLKMEFMMEMSQVIVRTVTPPNRVGCITAIVVDEAGTAISLSIYNQPDETMIKANDVLPEGSVCLIKDPFFQANKAGNSYNLRVDHVSDIILLRGGDERIPRRWRKSKATAANSEEIRQHGDTAALASAITPEQTRAALLNRSLANLRLHRLEKAVDDASKSQDDNVPTQKGLFREAKAYYSLEQFSLCSAKLRKVLALNPKNQDAKKELARTLRRIDEQDRGIYQWGQMYDQANATPPVIDCATYNGPVEVRRSTERGRGLFTSKAVKAGDLLLCEKAFSYRYAGEDDNMDANQNNRVLVSLVSKRTVLGAQASLAFNIIQKLHHNPRLAPRFNDLHHGDSHSGAAKQQDKSIIDTFFVMDVVSLNSYGSPRTCLIQFNGHLSHKKSTTCGLWILASYINHACVGNCQRSFIGDMMILRASTDMDANTELQFCYLPPDGLSYEEVQKSLQPWGFVCRCELCEEKKLVSEEALQRRQELIRDSESTMANSSTLSQQSKAERLLGRLEETYADGRTKYRLEIGQYYVLLGMKRLKRREPTGALESIIKSLEAYGFVIEAILLEKYSGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3M1</accession>
    <name>A0AAD9D3M1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_759376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371854.1">
        <property type="nucleotide sequence ID" value="XM_060515141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3M1"/>
    <dbReference type="GeneID" id="85399039"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051786">
        <property type="entry name" value="ASN_synthetase/amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43284:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43284">
        <property type="entry name" value="ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="720" mass="80730" checksum="9CFE2CDDD9CA156E" modified="2024-05-29" version="1">MCGITAAITLQRSDTASRNGDSNGTDGVKSKAKKISEHGTLRQQFQQSLEAIAHRGPDASGVWISDDATVGLGHCRLAINDLSPDGEQPLHSDDGKIHAVVNGEIYDHDAIRERCIKEHNYRFKGHCDSEVLVALYKIYGAPGFFKHLRGEFSFVIYDENKDRVIVARDRFGIKPMFWTVQNQGNGASKRMLLASEMKGFRAFGWEPEWNVYGLLSGSSMQADCTVFKDVRKLEPGNWMEIRDGEIKHRQYWDPEFKDKREVETRSAEEMIEGVRERLIEAVKLRLRADVPVGIYLSGGIDSSVIAGIVTKLVKEQGIELGNQDATKRIKCFTIQFPESSGFNEADIAERSADFLGVQILKKDMNETELADNFADAVFHTEHHNFDLNSVGKFCLSSLPQQHGVPVVLTGEGADEHFAGYPFVLPAFLMEPDLAWPQSDMTDGVRIPMYQEMTDDLKAMFDRIGMFEDESSSGGAAPTSNSMRLEPEWNAFSPWVRETYKTPGSTESTLAPEVLEKMIEKWHSLHTSLYVYTKGPLANMILTCLGDRTEMAHSIEARPPFLDHHLVEYVNNLPPSVKVAYQEAAGAAAGTGTTGTGASLWWKDLSPARQKLSEKWILKEAGKPFITQELYERRKHPYSAPVKWPRGGPVYNMIAGLITRENIENLGFMEWDNAKRWLEEGFGEDASPRAFRKLICTASWVVLSQRFGVKRAAMEQWSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6J4</accession>
    <name>A0AAD8U6J4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation transport protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_642132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358332.1">
        <property type="nucleotide sequence ID" value="XM_060509595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6J4"/>
    <dbReference type="GeneID" id="85393494"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015958">
        <property type="entry name" value="Trk1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF37">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002450">
        <property type="entry name" value="K+_transpter_TRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1708454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="660" mass="72919" checksum="13BB11BCECF572A3" modified="2024-05-29" version="1">MLTLTMPQSATNSRQRYQDEANSSKSGLRALLPPLNFITLHYAYFIGTTLLASAIFYGSSNPRGSISYVDSLFLVISAMTEAGLNTLNLSEMTVWQQVMLWLLIIIGSSVWVSIWTVVARKHVFEKSLRAVARAQKEGSRQDGGLSVSINNIAAAQEKGAASGTGLMDVETSTQPQAAGNHITIETTGNITRRSITSTHSDKTPTRPWLSFLSASKEGRNSQFHSLTGPERSCLGGLEYRALQLLSIVVPLYSVLWQVLGSLALGAWIANNMPTVATSNGANPWWAGIFFAVSAFNNSGMSLLDANVVPFQQAYFVLITMGLLILAGNTAYPLFLRLIFWAALRILRVTTAEETLVELKSTLEFILKYPRRVYTNLFPSRPTWWLFFMVLMTNGIDWMAFEVLNIGNPVIEAIPAGARVLDGLFQALAVRSGGFYVIPIASAYPGLQVLYVIMMYISVYPVVITMRHSNVYEERSLGIYDDDKMSPVSSHPDEKRDPSGTGILTHFLRENLSFAGVGAAKSEKRGSGFETRMSFVNQQIRGQLAHDLWLLALAVLIIVTIETSHFLEDPVHFSVFNVIFEVVSGYGCVGISVGLPKDAMSFSGGWHPGSKLVLCLVMLRGRHRGLPVALDRAVRLPGQRLLEEEEEDWRLRGARNRHEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8J2</accession>
    <name>A0AAD8U8J2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_638433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359457.1">
        <property type="nucleotide sequence ID" value="XM_060509365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8J2"/>
    <dbReference type="GeneID" id="85393264"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="154" mass="16393" checksum="9656BD54CB390AF3" modified="2024-05-29" version="1">MAENSHADILYRLPGACGKNQWCVEFHGYNEIGQGAWDVTCVDKPSIHTWVANTFSNPGQVTTCSAGWNNNGKRNLKATFEVDVMDAGGINRINPKEVYYQLGGKRIGVSRSGDSEVGSGSIIIPPGGSIQACVTAYSGQIINMLGALTSIVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8N9</accession>
    <name>A0AAD8U8N9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_724319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060512645.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="85396543"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9149" checksum="9B59B3A20F5E74A7" modified="2024-05-29" version="1">MPSSKGKPTDPELREEIKEEIKQEPNKSGGGEGQWAAWKGAKLAKEYEKQGGGYENEAGSKNEPKKGEPEKKSESKKKAETDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9C5</accession>
    <name>A0AAD8U9C5_GLOAC</name>
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        <recommendedName>
            <fullName evidence="4">FAD-dependent oxidoreductase-like enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000278">
        <property type="protein sequence ID" value="KAK1703569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060506776.1"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="289"/>
            <end position="322"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="420"/>
            <end position="439"/>
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            <begin position="452"/>
            <end position="524"/>
        </location>
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            <begin position="536"/>
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        </location>
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            <begin position="10"/>
            <end position="39"/>
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            <begin position="312"/>
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            <begin position="335"/>
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    </feature>
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            <begin position="363"/>
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            <begin position="420"/>
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            <begin position="494"/>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9V5</accession>
    <name>A0AAD8U9V5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_644024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000238">
        <property type="protein sequence ID" value="KAK1705642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357666.1">
        <property type="nucleotide sequence ID" value="XM_060509715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9V5"/>
    <dbReference type="GeneID" id="85393614"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
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        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
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            <begin position="22"/>
            <end position="112"/>
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    </feature>
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            <begin position="546"/>
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            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="64638" checksum="971495076E250112" modified="2024-05-29" version="1">MWLLNTKTLALESFTDPSEVGYAILSHTWGNDEVSFQEMSSTTMAPTTKSKAGFDKVAKTCEIAQEKGLGYAWVDTCCIDKSSSAELSEAINSMFRWYQEAKVCLVFLSDLRPEVGGTGPGVYEISDLSRCKWFSRGWTLQELIAPTVVEFYDAGWTLRFSKDEWPVCLSTVTNIDVEILTFEKELSAVPVAVRMSWAAHRRTTRVEDRAYSLLGLFDIHMPMIYGEGAKAFQRLQEEIAKGTDDLSLFAWVAVDEEQRYRGIFAKELAEFTFCGNYIRYNRLTSDRIEFSVINKGVRFTHLLGMDTEGSATWSLPFVTQGDCQICHYSHRIHIGLVFTAEGWVRATPGRCRYQSEVPHASGLIDVCVRRTVTASESRRYEQRPGHFFKLEWHPEDCLDRFGKLLFVEPSDLWDPVHRGFVGEAQTEDFMGIIKISLRALPSDVVVLLFLYKAKDQSPNVQLFLGSTWPWELKEGQAHYPEFMFSDIHMELYKRSLLYFSPSNLSSARATSGDRQFPADLTCTAEVDEEMRLIVSCKYIKGPQTAQEQEELPLLTNNSAQRLSDEPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA98</accession>
    <name>A0AAD8UA98_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_642621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000204">
        <property type="protein sequence ID" value="KAK1707761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358139.1">
        <property type="nucleotide sequence ID" value="XM_060509627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA98"/>
    <dbReference type="GeneID" id="85393526"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="100" mass="10936" checksum="565925E9BC235162" modified="2024-05-29" version="1">MGSPITVTKRVERVLPCCLFSVTCLARLLRYTREYIYGAGAPSLDLLAVSRLDNLTAADLLAHLAHFLALGIGPPNERKISHIIVPKAECKPWLPSKDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC49</accession>
    <name>A0AAD8UC49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_757633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358729.1">
        <property type="nucleotide sequence ID" value="XM_060514922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC49"/>
    <dbReference type="GeneID" id="85398820"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="26665" checksum="F95547B67E46D7D0" modified="2024-05-29" version="1">MDIYCESELLRDEIQDFDKWGWVFYRCTYDDDDAWARFKDIINDTSRQGSEYYKYPEILDKMKWTFLEDKEQFNGASTATLRSHFREWVKLPAQAGNSSETPPRESSPSSLESSAGITMYDEYFVQVDEVSLRSVVYKELPPAEANLYVRGHINLVNADWQPARLEDYHGENVIEEHFRFPDLEGCTEENVGWMRLAVSEIGPSTFQRIPHLWYIVYQRPPEIVYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCM3</accession>
    <name>A0AAD8UCM3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Superoxide dismutase</fullName>
            <ecNumber evidence="3 10">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_722096</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="3 10"/>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361531.1">
        <property type="nucleotide sequence ID" value="XM_060512437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCM3"/>
    <dbReference type="GeneID" id="85396335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000002">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="12">
        <location>
            <begin position="127"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1719447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="25139" checksum="718ACEF58A43EE6F" modified="2024-05-29" version="1">MSSTLLRTAPVLRTALRAGAGKPAAALASTSFVRGKATLPDISYDYGALEPYISAQIMELHHSKHHQTYVNGLNTALETVEDANAKGDYAKAAAQAPLINFHGGGHVNHSLFWENLAPASRDGGGEPDGKLAQAIKEDFGSFDTLRKQINTSLAGIQGSGWAWLVKDKTSGTLGVVTRANQDPVTGNLEPLLGIDAWEHAYYLQYQNRKAEYFDAIWNVVNWKTVAKRFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCT5</accession>
    <name>A0AAD8UCT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_657419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358415.1">
        <property type="nucleotide sequence ID" value="XM_060510959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCT5"/>
    <dbReference type="GeneID" id="85394858"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="58"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="727" mass="81261" checksum="E0B00D0153C16162" modified="2024-05-29" version="1">MAEYKYTPLGERDFRLLSLASGRFDDALQGDLLTRSIDTYVEEASKHEHELPESADSYEAISYVWGSNEKPYHITTSAGAKIPITESLYLCLKRVRLEDRTRLVWADALCINQADGKEKEAQIMLMHDIYLSAQRVLAYLGEEADGSSEAMELIERYWRVHIPDPLNAGARAFAEDLLGAPIPDAPTGAGAELPPVGADKWLSVSRFWNRAWFRRVWIVQEFILARDVMMMCGEKTVNWSQLWPGTIALEEPENPPWPLVDAKGEEIESAAELMANMAQRLRFYQLGAMRGNTRSHEHEGGHEHGGGCCGGDDHDDGHHEHDHGHEHGDDCDHDHDHDHEEGADGDDGDEGEWESEDEDEDDGGKRSTDLLNLLMSFREVDATDPRDLYFALLGLALDGDREEFRPDYSATFEQTALRFGRTLLHEPFSEELLDHAGIAEKHNGATQNFPSWLPDFRRPWRRMTVADAAESEAAGETDFDFGFDPNAEEDELLLKGIKVDTIEHMSGVPRAAHLHADHPSLWVKRDMVTLSQLLSNIPGFEDSMYPTGESGLEAILRALTFFRTEGEGSEEDEIPATTLKLAWRFCTAVEEDDLDAARPERDILRKEIMMSGCTAQEANEALEAAAQVLMNRIFPMRAALDLVLAKGGKGYATFVIFECSLTGYQITKDDKVEGLITVTIENVGERPGSKVDGTDSRRQPNALLGFEKVHSGPGVQEALQTHDLVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD82</accession>
    <name>A0AAD8UD82_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_757034</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359418.1">
        <property type="nucleotide sequence ID" value="XM_060514837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD82"/>
    <dbReference type="GeneID" id="85398735"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="8">
        <location>
            <begin position="4"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1712561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="23351" checksum="97BB60FAA5FBA6A9" modified="2024-05-29" version="1">MSHELTLIVAATRNMGIGAKGGLPWTGLKKEMAYFARVTKRLPPQAPSDARNAVIMGRKTWDSIPPRFRPLKGRLNIVISRSHPAASLDSSSAAATDFEKDAVKVSSLDQALAFLRSDASGVATGKLGKVFVIGGAQIYGAALEVPEAKRVLLTRVVGEFECDAFFPLKLGGDDGDGQWAQIEKKGLDEWVGEEVEGGEIEENGTRYEFQMWEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDL1</accession>
    <name>A0AAD8UDL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_637199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359819.1">
        <property type="nucleotide sequence ID" value="XM_060509291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDL1"/>
    <dbReference type="GeneID" id="85393190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="80" mass="8891" checksum="F2FDDA57E2BCDA5B" modified="2024-05-29" version="1">MFVLRGTAATGLVLPWVRHRSCGGPDSLCNNLLFSSRVYSIRSWRLGAQLMNVLGRTTAATVYPTLSEKSNSSHYLQRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDP8</accession>
    <name>A0AAD8UDP8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_439218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362056.1">
        <property type="nucleotide sequence ID" value="XM_060503093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDP8"/>
    <dbReference type="GeneID" id="85386992"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H1 N-terminal" evidence="2">
        <location>
            <begin position="98"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="16007" checksum="2F03C546A4F9A225" modified="2024-05-29" version="1">MANTPTTSPIRVQTRQEQLTLRAVAQKIPIPTQPEPDSTDSTGHSDNEDGSEASSGSRAENDAEPSDNPPQTSVADKVNDQMRKYASGIPKELSGAKKYFVVWNGMETGIFGSWDKCQPLVKRYPGAGYKSAKNYNDAVRHHSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDP9</accession>
    <name>A0AAD8UDP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358850.1">
        <property type="nucleotide sequence ID" value="XM_060509480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDP9"/>
    <dbReference type="GeneID" id="85393379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27223" checksum="5BE91B27ABB558B6" modified="2024-05-29" version="1">MGWTSPGLLRLDDYKCHCAVWRFRPSPRSSALTCTHCCRRDFSYTFSSLLQTDMSQLPAQPSCRPPGHLSDEGNLAYQQPTAAGSSKSAKVSSESAQRGSQYLRNSPAGMNAQSAVTGLRRSPASPDAIDIDRLLAQLQDSTTEPSSRHAREAQLSPGSGQTGNRSLENRMLSGVQSDLPMHSIAERLERLKKGLCRLEEAKEFQRKKVGATNNQLGRINEDVRKIKTSIDSLMPPLPFAGNSFGDGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE57</accession>
    <name>A0AAD8UE57_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_628878</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362577.1">
        <property type="nucleotide sequence ID" value="XM_060508728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE57"/>
    <dbReference type="GeneID" id="85392627"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="901"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="905"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1722522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1108" mass="123576" checksum="32B6A9B92AE72328" modified="2024-05-29" version="1">MNKTPQNGTVYGQQTAPPSMATTDRYDLLILTDATASMSSYLQALNKSLPEIIRISALTDCFDRIGVMAYRDYSASMLTEWSGWYSTSSTADDTITQGQLLQKASHIKADSGTYGLDWPEAAKTGLARAYSIMRPEATTIIILYADAPPHIPGTSSKHRATEIQNLSKLDSFYGCGKYFTDWIAGAKILRDGEKKAKVFSVIQGGIEYTVAPFTFLSHITGGVSFKLDNQHNVPTSVAISELTTGILMAWMGVGKEGGAASGQRTYAEACQYRTASNIEDVTSEEDDALELYFAIAKHMERTVMNNIKPTPTKLDELRTVVEARKTPLLDFSKRYKADEVYRSFVVGQLETLIAADVGTIAINPVFGSLWRAVCNDRDNPARDGLIQAFGYSVDRIPEPEKKARMKAWLEESYDYAAEISEVIDKVPEHQRYPCVFLDPTEQFQTSTDDNGEDATADKRAVTEFTREELLEIGRSCDNRILQRLGKVLTRLTYVAREEDLPAHIRADPNVALIPMALSSVEYQRKFWKILLHLILPGTMLAARPAALLAALALRLGIRPLTATADRELLTFTTKWNNLDIPETWNASCLSLLLDASEDYERRVAQGVTQRPAPKACVLLESDRRLFETLVDYKLLELNLNTTLQAKIGWHPDKSKVSLGPLAICKRCEFPRSVTIMGPDNVCGLCPKSNRCDCKVCQTAPDQEARLQNNVTRGDTEETEATWVECFTPTCRAQYVVYNPQALNVRAKCYYCRHHGFVAAKDKIPREAPCVECSQCRSRVIWPETYRPSDLDLSAFKCPACTANRVTVIDFETSAKTLTGENGVSWLLRNDDLAIKDPFNGRSLFYTISQVEESNRELLAKNVEIIPAVHGQAKLTIRGKAIQNQDSILESLREWVRSRRTEAGVCSLCFSNIRKTDLRNACGRSGCHQQICNGCMKDWYGLNVRGRLLNLAALSCPFCRRQPTAKTVSSFGISHIGDLQTATTDKEWIYGWCRDCGFAKKYAERVCAVGVPEVSNWSCDECKEIQIEGAQRLRVRNCPGCGTVTEKMGGCDHITCTVPGCNAHWCFACGENVGEEDIYDHMSDAHGGMWGGYHADEDDYDYGYDNEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEC7</accession>
    <name>A0AAD8UEC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_590595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000156">
        <property type="protein sequence ID" value="KAK1711627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359180.1">
        <property type="nucleotide sequence ID" value="XM_060506350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEC7"/>
    <dbReference type="GeneID" id="85390249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021460">
        <property type="entry name" value="DUF3112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35184">
        <property type="entry name" value="YALI0C10208P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11309">
        <property type="entry name" value="DUF3112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="458" mass="51037" checksum="DDA8ECE35D0928D8" modified="2024-05-29" version="1">MGAPDPANGAFPGGIPNKNIDLPVTIMFMVLFMLGAYVHLSIYRRNAKRGHKFLISDIVFDFCMIRTVTCIFRITWSIVSTRGVVLLALITENGGAALLFAVNIFFAQRLVRSIHPKAGWCTAFSQFSLILLFSVPAFIILNMTSTIIAFFSVGNVDRLETTDDLLKFGSSWNTFLSIFPVLVVSGCLSVPGPKPEKFGSGSQRVKVALLYLGSFLLITGQSIRLFAVFNKELPGVTPSVIYGKAVFYTTGFFFELIVVALYAVMRVDLRFHVPNGASGPGDYSGDSDKGSYSVEEIERLIDGLEVPHQIMRERKGPEDMEMVFTIFFATKDAGKNKEKKEAGEGSDETSSGTNAEDAVLPERPKRITRRQTLIDAINRPPRPPRTPSAYPDIPDMYAQMGEPEMPSRRPTRQSMYSQFDNRQAYDTRADAQYQQQYWGASPPYGNEKEGMKSIDLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF02</accession>
    <name>A0AAD8UF02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_635122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360494.1">
        <property type="nucleotide sequence ID" value="XM_060509147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF02"/>
    <dbReference type="GeneID" id="85393046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="511" mass="58840" checksum="23DA001194754F9A" modified="2024-05-29" version="1">MATFFHLPRELRDMIYRLYVVSDGGYVLNPESNRLRNAMGRPIDLALTYTCKRVADEMRGLALEANTITVSTFYSPHERHRARDFDVVMTMLHDSLQSALNRAELFLWDDICAEISGTFPQFTPVLDMIKHDTWHSTQGRSSKQGPWGEPPSVYRDFVRFALQTISDLDYRHRFNDEFAKAFCNTDDIRPLLDLDPAPWMIPTQYDLRQMVDMLGGKSSLRSFGFVRGWMGSESATRRAMYRYSAAAVGIRFLKSNTLATRAHLRDIVLIEDQESVSNPACHAMGLIPFCQENPAMRIERRVSLWHNAFFYHSSMSGATGWRTKEYRQVEANEMSFAVARWVIETLPLIPAGMPANSFTLVLDGEGDPQCTEIFQTVVLRDAAWQQAMDECFQSGDLPPEPYGMRRNSQRNYVGAIFPAFNESYLFDKFPQAMQEIVEGTSMVRCTFDPGEIVDVQRLKSIAKRESWSLDHWRVKWYDREKKTYETTPPLPSWSAIKAGYLSNRHVGPFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF99</accession>
    <name>A0AAD8UF99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_763672</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359675.1">
        <property type="nucleotide sequence ID" value="XM_060515219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF99"/>
    <dbReference type="GeneID" id="85399117"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF12">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_6G13830)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="267" mass="28695" checksum="53076F4058462F1D" modified="2024-05-29" version="1">MPLYQPENLYAPILTQFSLNGKIAVVTGGSRGIGAEVVRGLAEAGADVAFIYKTNTEADETAARIAKETGVRVQAYRSDVTSRDTIAKTINQIASEFGGGRIDIAVANAGVCANVKSLEYTERTWQDMNSVNYDGVMWTAQAVGNIFKKQGRGNLVITASVSAILVNVPQEQAAYNASKAAVVQLAKSLSVEWANFARVNCVSPGYILTEMLTKQPKELMEHWLSMIPGGRVCHPAELRGLYVFLASDACCYMTGSNVVIDGGYTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFG5</accession>
    <name>A0AAD8UFG5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amine oxidase</fullName>
            <ecNumber evidence="9">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_630432</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="9">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="8">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8 9">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362098.1">
        <property type="nucleotide sequence ID" value="XM_060508826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFG5"/>
    <dbReference type="GeneID" id="85392725"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF91">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0186">Copper</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="11">
        <location>
            <begin position="252"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="711"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="7">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="8">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1721302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="731" mass="81221" checksum="4EA2AAC834359A98" modified="2024-05-29" version="1">MAPHPLTALSGDEFTAARDIVVKLFDQKVSLFFRCIFLQEPKKEELVPYLQAEHAGKLTDETPRPPRRARVQYDVIRSGKRPEYTQSVVDLKTGRELERTVAAPQYQTSYTPDEFGIFQDACVASQLFKDAMAEFSLPKNFTVTIDPWPYGGPDEDEGDIARLMQGLVFARDASKNNVDSNHYAYPIPIIPVMDIATRKILRVDRLATGAAGDGLAPQPRAAEPKSLFSNNISSEYVPELLEIPQREDLKPINITQPEGASFAIQPDNLVEWQKWRFRLGFTPREGAVLHDLCYDNRPVLYRLSYSELTVPYGDPRPPYQRKQAFDLGDGGFGRVANNLELGCDCLGAIHYFDALMADTEGNPTVAKAVVCLHEQDNGIGWKHTNFRTNRAVVTRLRELVVQCVVTLANYEYVFAYKLDTAGGITLETRATGIMSVVAVDEGKKESAYGAVVAPGVLAQNHQHIFAVRIDPAVDSYADGDTRVLVEESVPVPLNKETNPYGNYYEIRKQVVERACWIDAEPKLNRVIKFENRTKKNAMSGRNVGFKLTPSASQLLLADETSQVSKRAKYARHHVWVTGHRDDELWAAGEYTNQSREEVGGVWDMVQRGDWFEDERGANGDGGGCDEGRKSSPVVWSVFGLTHNPRVEDWPVMPVEIHHLTIRPADFFTSNPALDMPTNKNETSVIVPCCGGQETNGDSKEGGQAVQEAALTHLQGPGPDVSAAEAGAHTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGC4</accession>
    <name>A0AAD8UGC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_626526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363436.1">
        <property type="nucleotide sequence ID" value="XM_060508571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGC4"/>
    <dbReference type="GeneID" id="85392470"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="95"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="336" mass="35938" checksum="7CB1AB657B566968" modified="2024-05-29" version="1">MRLPRPPFDPELAPIQAAFEPFGPITPEFVINHHARTDRTLEAPHIAAAEAIGDRPLTYAEHTAPGLGLNDPPIALSIFTPNTAPVDDKKRWPCIFYAHGGGLIFLHRLVGLSQPLDWAVAAGAVLISVEYRRAPEHPQPAASDDCFAALKWVQASAGVLGINAARILVAGQSAGSGLAAGLALRARDAGLNPPVHAQMLPCPMLDDRCKSISCAQFDDGVEPWDRTKNAAAWAIALGERAGARARAGDTVSSYWAPARAETLVGLPPAYIEAGSAEFCRDEAVEFASRLWSAGVSADLHVWAGGFHGFDEMAPDSWLGRRAIAAKLEWVQRVLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH31</accession>
    <name>A0AAD8UH31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Quinon protein alcohol dehydrogenase-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_706088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361488.1">
        <property type="nucleotide sequence ID" value="XM_060511522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH31"/>
    <dbReference type="GeneID" id="85395420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="704" mass="78577" checksum="D8E872E2FF467689" modified="2024-05-29" version="1">MIGQLFAKPTKRLRIAGPREKDWNDRLTGYLFSEDAYAVTCCTRLLAVGLASGEIRLFHLAGSGAFDAAATLNHGKRVRLLAFDRASSVLVSCSSRNLQIWDTHWSQEPIRLSPVWSRTIDFTPGSISFDHDEQMIILSNPHGNSLVIYDIKDGKEEERKVLHAPSAWDSDSSDENDNELGLWTPAMQIRLDSNHRLAALSYRNASVSIWDWNTSVCVGNFEKHYIDYTYATSQVLDMVFNPIAEVELLAISYMDGDVVTCNPWTQDQANKYHLQTLLSVLSTSSDGRVLAGAAEDGGIYLFLFETLQPIYHIRLPGDQLRIQDIAFSADNLRFFDIRGQCCNVWEPIVLLAKDGYDDNPLETSCSSEEIPLPEIKASRSHVYQWGESITAIEPANNMLLVGRQDGTIDVSDLNTGEIVEKLRIHDAFAEIKSLDWNEDTCTLLSIDTTWRHIVTRVTSMGRGPGAQVTYLLNRRGDSDTSQIILSTEAESLLVCTNSSAALIALDGTVMGEEKDLKGAWWLRHPSSPSHLLAFQDNYCHIYEWCNLKRVCKSVDLSPSPQIQVSKGCPPWLSSKSSSYLARGLRRATEQTSSIIAVEASKIAPSTEAILTQSLHITSTSLQSVIGCIKSSLLFLDTAGWICSISLRNIADAHHFTRHFFIPLTWRSEVDAVVKIVSKTAIAFGRGEHLMIFHGFLEFEERIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHH5</accession>
    <name>A0AAD8UHH5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenine deaminase</fullName>
            <shortName evidence="7">ADE</shortName>
            <ecNumber evidence="7">3.5.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Adenine aminohydrolase</fullName>
            <shortName evidence="7">AAH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AAH1</name>
        <name evidence="9" type="ORF">BDZ83DRAFT_584721</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenine + H2O + H(+) = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHH5"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01320">
        <property type="entry name" value="ADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000039">
        <property type="entry name" value="Adenine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01962">
        <property type="entry name" value="Adenine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028892">
        <property type="entry name" value="ADE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114:SF6">
        <property type="entry name" value="ADENINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="14"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="39598" checksum="2D8A840CE92C51E5" modified="2024-05-29" version="1">MCKDGLHDFLVDLPKCEHHIHIEGSLGPELLFHLAAQNNITLPVDKDPAFASVEALYERYRNFSSLDDFLHYYFIGFSVLLTVTDFEELGYAYLKKAHSQNVRHAEVFFDPQAHTCRGVAYETVIEGLRRAKERAQRDFEGLTVEYIVCFLRHCTVEDGLRMFVEARDAGHFADGTIAGVGMSSSEAPYPPKMWTSIYDAVRAAGVRATAHAGEEAPAECVVQALDDCGVTRIDHGRRSAESPELLARLARDKTLLSLCPISNVVLRGVKEMKEMPIREFLDKGVRFSINSDDPAYFGGYILENYCAVQEAFGLSIEEWKGIAVGSVEGSWCTEERKDVLKGEIEVVVSKYAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHQ3</accession>
    <name>A0AAD8UHQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_630661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361935.1">
        <property type="nucleotide sequence ID" value="XM_060508847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHQ3"/>
    <dbReference type="GeneID" id="85392746"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042245608" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="50" mass="5245" checksum="BB3DCC785AB0869F" modified="2024-05-29" version="1">MWSVGLLFFILFWLGSIGNARGTLTSLKSGSMSIANGAVCQLARRLGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHU3</accession>
    <name>A0AAD8UHU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_752456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. Reversibly leaves the enzyme after glucose depletion, causing the catalytic subcomplex V1 to detach from the V0 section.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364602.1">
        <property type="nucleotide sequence ID" value="XM_060514204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHU3"/>
    <dbReference type="GeneID" id="85398102"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="44016" checksum="FB188B63FF37A920" modified="2024-05-29" version="1">MSTKYALVSLPLGIFDSGDKDDAISSLSATISAENGSVRPFNIPDFKIGTLDALVQQADDLAKLESTCQAVVAKVADSLKSILDGDEDKISQQKMVNDKPTDQYINSFSWNKVRYRADKPLSELVDTLQKELVTTDNDVKSKFNQYNSVKTNFTTLQRKQTGNLATKSLTPVVDPALLIQDSEYLETHLIVVPNNAKKDFLKSYETLAPMVVPRSAVQVATDEEFTLYAATSFKKHSAEFLAKCREQKWTPRQYKYVEGGKEEEQRELDRVAREEKKTWGEALRIGRTGWSESVMIWLHVLALRVFVEAVLRYGLPLDYVSVLVKTNSKLVKKVKTALDSNYSYLGGNAFGRDKRGKITKDDAALSSEMAAVGLGGGEEHEYTAYVYYEFDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI69</accession>
    <name>A0AAD8UI69_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_676869</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362058.1">
        <property type="nucleotide sequence ID" value="XM_060511163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI69"/>
    <dbReference type="GeneID" id="85395062"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF23">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="57"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1721262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="54214" checksum="0DC4F445C4276F53" modified="2024-05-29" version="1">MDMDKTEQSSDQVEDVNADKLSQHGGNLMMPASLAALSQEEYERTGKKATLKMDLVIMPIMVIMYILNYLDRQNIASAKLANITTDLNLSQVEYQTTVSILFVGYILMQVPSNMIVGKIKWPGAYICCGMAAWGVISSLMAVVHNYEGLLMARFFLGFVEAIFFPGALYFLSLFYNRKQFALRTAILYSGSQLGNAFGGLFAIAILNLDGAHGLAGWRWLFLVEGVITVGLAIPFACILPNSNKKIPTLTQLECEWVQYNFAADQGQEDDSSEVTAMKGFMMAVTDPKTWMLMGVLYSTYIVGAVANFFPSVVGGLGFSRTMTYALTAPPFLLCVITMLLNGFHSDRKQERFLHIVIPLCITLVANIIAVSTTNTAARYVAMMLLPGSFYAAAVVVLSWITGSLAQPSVKRASAIALINAMCNTPNIWGSYLYYGAPRYVTAFIVNIAATGLAIAFATVTRIWLTRLNAKLDRGEDTGKHGPTQAQVAGGFRYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIR4</accession>
    <name>A0AAD8UIR4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_621058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365127.1">
        <property type="nucleotide sequence ID" value="XM_060508227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIR4"/>
    <dbReference type="GeneID" id="85392126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="240" mass="26055" checksum="698AEF4C0D7C2D75" modified="2024-05-29" version="1">MANTGAPPNYYKILEISEAATTQQVRDAYKKAALKTHPDRVPADSPERATRTRKFQLVNDAYYTLSDTQRRREYDAQRKIFGASAGTTYGDFSDDDSDPEEVPPQAGPNPQNAYSWAWNFFTGGKQGQQNEGQRAQADNAQFGDVFEEMLREEGMAEEGTNRPTSSFWSMVGGLSGGALGFIVGNMPGALAGAVAGNRLGSVRDAKGKSVYAVFQDLPQADRARLLTQLAAKVFSHTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKR5</accession>
    <name>A0AAD8UKR5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Siderophore biosynthesis</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362300.1">
        <property type="nucleotide sequence ID" value="XM_060512390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKR5"/>
    <dbReference type="GeneID" id="85396288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251493" description="Siderophore biosynthesis" evidence="2">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="21322" checksum="197326711A5246A9" modified="2024-05-29" version="1">MSFRYITSLAIMATAVLAKTDLAGCVSSDSVVTPTQGGTPYATRVWYVPGTGEICAALDCGGGRAPPKTTVPGCPSYEGTETYSPSFLPLQTSAAPVVSTTVAPVTTTAAPETTASASDSASVATVTTSTDSAAVESETSASATAVVITSSGFSNATMTTLTTTAASGSGSQSARSTRAVGSAATTAATTNSPNAAVPTGASRELFGLVAGVAIGAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL94</accession>
    <name>A0AAD8UL94_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable endonuclease LCL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Probable endonuclease lcl3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_624386</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LCL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364065.1">
        <property type="nucleotide sequence ID" value="XM_060508441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL94"/>
    <dbReference type="GeneID" id="85392340"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000029">
        <property type="entry name" value="Probable endonuclease lcl3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TNase-like" evidence="16">
        <location>
            <begin position="85"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="249"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="249"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1724010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="285" mass="32065" checksum="204786A0D9A6C9D5" modified="2024-05-29" version="1">MPWPFSSSSSGRPPTPSKSEDDARVLPTSWNDLLPQPEPPLQAAREWAPVFLTSVASLAAFMFWQTRLRRFPTTNHIQPELFRRRTLLGRVTSVGDGDNFHLFHTPGGRLAGWDWLRKVPNTRAALKGKTIPVRMAGIDAPEGAHFGRPGQPGAAEALQWLRGYIQNKRVWARIHRRDQYERVVATVYVRPFLFKKDVGLEMLKLGLATTYEAKTGVEWGGAEEAYKAAEARAKSKKLGIWNGKASDFESPRAYKTRTNDTEGKPEGKPEGKTEGKKTGWLSRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMV4</accession>
    <name>A0AAD8UMV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_751384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365792.1">
        <property type="nucleotide sequence ID" value="XM_060514042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMV4"/>
    <dbReference type="GeneID" id="85397940"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104421" evidence="1">
        <location>
            <begin position="23"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="107" mass="11645" checksum="1A2AF54327ABC876" modified="2024-05-29" version="1">MLITNILTAATTACAIFAPAAAAYDMRVKKYGKTDCSSSGGGNLDWNANECHALYSTDWGMKVIDYDTKCKMRGYNNGNCRGSAVTAFSTRQCHSLKGVWSVRVECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX0</accession>
    <name>A0AAD8UMX0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein PNG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein png1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_650081</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366826.1">
        <property type="nucleotide sequence ID" value="XM_060510346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMX0"/>
    <dbReference type="GeneID" id="85394245"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.620.30:FF:000004">
        <property type="entry name" value="Peptidase (PNG1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000011">
        <property type="entry name" value="peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="7">
        <location>
            <begin position="399"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="556"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="624" mass="70082" checksum="6AF2611A927A7B15" modified="2024-05-29" version="1">MNLCRPQPVGWVPRRRNNIAIVVAGRQPRSDSQLSYEQVGYGRGASSPPGTVRPSSPGGLRRRCLASLEIFARRDSSVEVRATQALAQTRAKDVKGPQKSRSSRLCPSEQPEKGLARESSVEDPLSVPPPPPSPFFDTLSIHIHLTTDDFEMDGHGYPPGEGPPNGDGEYGEEWARDLRVKFESLLRDKRMTELRTTSRQGTPQPRESASSANLRGLASPGPGRPSTSHSSTPMPPTPPAYSRHLPKIPTPPAAHDRDSQKFRNLMISLSLTPTKYENPGLLDEALQCIPLDRIYGEAEEECQVMQAEAESMGDGRKATWGYQDCVIRALLRWFKRSFFTWVNNPPCPVCLSPTIAQGMTPPTPDESACGALRVELYKCSAGDCGAYERFPRYGDVWRLLHTRRGRVGEWANCFSMLCRAMGGRVRWIWNAEDHVWTEVYSEHQKRWVHVDACEEAWDNPRLYTEGWGKKMSYCIAFSIDGATDVTRRYVRKSDFCAERNRCPEEVLLYILNEIRGLRRGNMNKDEKFRLEKEDSREDRELRGYVIKSIAQAVTDLVPGMPSPSASSAPPPRQAAPQRRDDTKLPAEQPGRQTGSAEYLAAQANANARHHQFPPHDPSRRRDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN49</accession>
    <name>A0AAD8UN49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364889.1">
        <property type="nucleotide sequence ID" value="XM_060514167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN49"/>
    <dbReference type="GeneID" id="85398065"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="18835" checksum="E69D44A700448B9C" modified="2024-05-29" version="1">MPPKTTTSEAAATLNLTDGELKLALAMMKHVDRPTTAVLEKMAEEAGLSGASSARTLLARAATKHGWFAGGGSSNSTEDGSGSIPTPRPKKAATPRKKKIAEVEEGAEEEGTPTKKRGRKGKAQKAAEEAAAEAAAEAAALASAAEAAAEKDVDDEEMKEGGDGSVKEETGDTDGGKEEAVEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNK5</accession>
    <name>A0AAD8UNK5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_577728</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364863.1">
        <property type="nucleotide sequence ID" value="XM_060505050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNK5"/>
    <dbReference type="GeneID" id="85388949"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF34">
        <property type="entry name" value="PROLINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="128"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="467" mass="51932" checksum="00D63F55DD33CBDC" modified="2024-05-29" version="1">MTTRLVACSRAPVPFCRSLRLQQGAARYVSTTAAKTQTLSPTAPRTFTPTPKKSPLSRLSTKALVRSLFLTQFMSTPLLMKPALPILHFIANTKFALFNPDKNPLLNRLLRWTIYDHFCAGENIPQVSKTVSEVKQMGYQGVILNYAKEIVLDKKAAAAETKAGEYAPEVYQMVDQWKKGNLETLHMMAPGDFLAVKITGAGPISVDALKAKAPIPEVLSKALDELCEETNKQGSRLWIDAEQQALQPQLDEWTIDLMRKHNRQSKPLIYNTIQGYLKGSKANSERHISLAAKEGWSLGVKLVRGAYIENEVRSLIHDTKQDTDNNFDDIADMFISQRLPEDAKECQFPASALFLATHNAASSATAISTHRRRILDGQATTELECGQLFGMADELSCELLDNYDTCVADSGLKRDAIPKPFKYLPWGSVSECMGYLHRRAVENKGAVAESAHMLGSLKTELRRRVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNM8</accession>
    <name>A0AAD8UNM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_652977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363665.1">
        <property type="nucleotide sequence ID" value="XM_060510578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNM8"/>
    <dbReference type="GeneID" id="85394477"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047580">
        <property type="term" value="F:4-hydroxyproline epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.10:FF:000005">
        <property type="entry name" value="Proline racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442:SF5">
        <property type="entry name" value="BIFUNCTIONAL TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE_2-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029792-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="37502" checksum="8FEC7210A66DBC74" modified="2024-05-29" version="1">MTIGRTFNVVGAHCGGEVCDVIVGGVLDVPGKTMFEKMMHFWKNADHLRNLLMNEPRGSSSMCVNLVLPPCNPEADAGFIIMEHEEYPPMSGANTIAVSTVLLETGMVPMQEPTTTLRLDTPAGLVTVKAECKDGKVTFVEFQNVPAFVYGLDLDIKVPGFDTPVKADIAWGGMWYALVDANSVGLQIKTENGKELVDIGERIKRAIQTQTSPVHPENPEIRGVSVFEFTDPLSPYAPDTQQTAVNTVVVSPGRLDRSPCGTGTCARLAVLHKRGQLAVGGSFRHRSVIGTEFIGTVKSEAKVGDYDAIIPVVKGTAWITAFKQVILHPTDPFPEGFRVGDKWHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP43</accession>
    <name>A0AAD8UP43_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OHCU decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_261840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366362.1">
        <property type="nucleotide sequence ID" value="XM_060501998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP43"/>
    <dbReference type="GeneID" id="85385897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="18937" checksum="CC905DE4AB9399D7" modified="2024-05-29" version="1">MASLPDVNSLNSLPVEQQTKVLDALFEPSPAIHAFLLPSISTTSFQSYDEFINQAQKIFEALAADPTQKAQLHSIIGSHPRLGAKKVESAQSAAEQAQLQSGDAAELAALNAEYEEKFPGLRYVVFVNGRGRPEIMENMRARISRADLALEELAAIQAMCDIAKDRAAKLLAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP75</accession>
    <name>A0AAD8UP75_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364911.1">
        <property type="nucleotide sequence ID" value="XM_060514171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP75"/>
    <dbReference type="GeneID" id="85398069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="562" mass="59425" checksum="CA863C555D01FC7C" modified="2024-05-29" version="1">MDATATWSTLRQRRRRTVPKFPGRPRHNLARRQSPAPPPAKEEEAEEADGEQEAGGKQEEEEEDEEEAKPNQPANQRKEQEEEEEEEEEKPLGGAAKQAESDSEAGGQAGAASSASDSDAPQPGAPPGQQSDSSSDSEQEQPPPAVSPPPGAAPAPPPGIQPPPAAPSLPPPAAQGSPIPSAVLNPALPASLPPARGFITLVPGAPPPSNPPPQEAPAQQPAPVATPSNPPARQPQNPPLVSQPPATPSPPPPPAAETTPSTNLPPPPVENAASGTPQPELLPPSSQVEASNAPSASAAPADGTDRGFAIGVSFAVVAIIGLLIGAVIFGVKRYKRKKKVAAVATNMTQNTPPGGNGSLPRESAILRQPKRSTREMERAMVTTFRQTKIANRTTKEMEEQMMEQFKTDRASRVDASSARPLPNPSTTNAAAAVPPLPSMPNNNDPVGNTRNMQAESFYYEKSINEPTVVPAPLRISTAQRRPPAAVSTARVPYPASTYDMYQEVGQGPYRESINIGYQPNNNNNGYRPYNPDNFYQPQPGQLPRAERGPDGRFSPEMGYRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPN9</accession>
    <name>A0AAD8UPN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_609802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368352.1">
        <property type="nucleotide sequence ID" value="XM_060507556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPN9"/>
    <dbReference type="GeneID" id="85391455"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="22796" checksum="37E7D1A31AD3773B" modified="2024-05-29" version="1">MLKFFAARTAPTRRTCEYLEENHPSQTAWRRHPATQYLSSLAEQANPVPVEAPSPQKKELQRQNNPRHTHGDKTVAITSSFSTPLQPDRATLRITTSYNGRLPFRPLLSRPCRCVAVPLDDPCRVHRHSPPPPAALKAPSLSHHARSQAPNTPPFCLCRRLNPRLLRHIGWESGKGPNPIDTTKPPKSNQKGQRGHPSLCNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQE5</accession>
    <name>A0AAD8UQE5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_748839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368772.1">
        <property type="nucleotide sequence ID" value="XM_060513675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397573"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF2">
        <property type="entry name" value="MIGRATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="3">
        <location>
            <begin position="953"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1308"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="162"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="814"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="842"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="906"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="936"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1133"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1169"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1236"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1259"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1271"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1327"/>
            <end position="1344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1380" mass="152173" checksum="6817A66487E98229" modified="2024-05-29" version="1">MAVWETEDESKGNAAVTALPTPQDTPYRTPSRSSRKSRRSVTPPNGKKSPSPPPVPQNDKGSKRSSRNMTNDDGISVLDPRRFTPTLHANLVAEILNLRRDQEEKAKLIENLELSLHASRQEQETLQETVATTTKQSRSLQRQLALLEGGTSSALGELARERDEAVDSITETRKRLESAQKKIRSQEEDSQRVHDLWAQDKDSWEEEKRKYERRVHVAESRLKVVIDEVAAYQAAQMNGNGNDSETEDQNDAGSVRTMSLTNSVRFSMQQSPGKVFNGNSLADELNLDGDDDWQTDDGGRESAMSNYRHTRTFSRDSILSKIHRRQQSMESPQRPGSVTRGRLWMNQPVLEALEDGIQENDEDLMPPPPPPAPKVSYTDTGIQFSPPPSPKMEPAKPCTPEPPAKIEKLTEVEASPRGEWEVEANQRRKRVHVNRPLSIEPRPFNHMVSAGSQTVEEPLSPPKTPKSPYRSSTPPPPETPPTVMVSSSTQTDKPVERPQTPPVLRPVQELTIPSISIIPPTSRPTTPREHRLPQYVKDFGCQVSIISSAPTKSTAVQTEEILSDKRLATLPVHLRPSAITSRPSSPSIGIATAVTSDDPRHFTPVPGHLPPRNPRRLATKRSLSDMPSSPPVSPVFGEQTRDAYPGNNDDGPLSREGAPMRRPHRISSLFAGFQDAQSSDEVDEFDADMSDSEYRTALSAPGMRMTDSRASNRTSVSTFTSPEQTKRSAPSRNSMRLANDSYGGNLESREAPKRQSAKPTTRGYEKSTAGPSGKNVMRKAAMIQSGIASHQGRPRSPSVPESRAPDPPFPIPTRASSRRPPFSASAPSDGQRSPTKMDAPWHRRGMGRNHYRAGSIHRANSIRKVRSAAALPRNQRNRKQSRSPPPFSETTDAPESPSLPPLPYNDITSPRYDTSSNYRSHKSRLSTTTAQTATTDVNSVGGASNGASQATGVVDAIAQTMVGEWMFKYVRRRKSFGVPDNSKDDSSNDRHKRWVWLAPYERAILWSSKQPSSGSALMGKTGRKLTIQSVLDVKDDNPAPKNQGAVFNRSILILTPQRALKFTATSSERHYVWLTALSFLAHSTQAIPEIVAAPQPAKPTTVPDFEPPQPTRRPGIRDSIRLTKSKAPSVKNPGPRSIPSVPSIPSIPSSRTGDVSGYKHTEAFPPMPTNINSSSNTNNNNHQRERSGDAAEPPFIPRFTERSNQNAVHGRKRSNTGGHVPPPLSFRGFSGPGSVGQHSYTNSNAGNSVGTAGSSDIYQSQPSQGSSRQSWGMSTAGSQRTSEASSRPPGANFFDAIGTVRMEAFISPLAHSGFDRDPDEYEEYGYRARRRSKELRRRQSRSRHRDSYSSRGTRGTDGYHGSSRATVEDDYFRDDPFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQG2</accession>
    <name>A0AAD8UQG2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin HHE cation binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366480.1">
        <property type="nucleotide sequence ID" value="XM_060504712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQG2"/>
    <dbReference type="GeneID" id="85388611"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="1">
        <location>
            <begin position="38"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="267" mass="30336" checksum="981F10EE38367028" modified="2024-05-29" version="1">MAPTCIYADHPYSLIPTPTYQNSTSEKDPDMFTRIASKMALVHNMILRGLNSIYLQAPHVKASESKAFFQYILAWYSLLHVHHSGEEEHFFPAIDELSGQKGLMDGNVTQHKEFHDSLASFKQYVDSCVSKKDKLDSAKLMTLIDGFGDVLTKHLRDEIPSILELRVFGADKMASLEKTFEEEGEKSMKALGLIKGLPFCLSNHDIAFEDHQWTNWPPTPPVVKLICRHVTYQFKKKCWKFSACDKMGNLKPLYAVAHEDTKVGPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQU3</accession>
    <name>A0AAD8UQU3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_740639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365584.1">
        <property type="nucleotide sequence ID" value="XM_060513067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQU3"/>
    <dbReference type="GeneID" id="85396965"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="459" mass="52394" checksum="7D1AD31EE8B67DD7" modified="2024-05-29" version="1">MSNLNDQKQSGYLLVALQITPTVFLFVWLLYQRLFSPFAKVPGPYWASLSRLWLAYHSYIGDLHVVTMRLHEVHGKIVRLAPNEVSISDLTSIKTIYGAGSKFRKSDFYSVWQGRRKFDIFPERDDRVHSAQRRLISRPYAMTSLKELEPYVDSAIQGFLEKLGGMLGRTVDLGNWVQLFAFDVIGEVTFSKRFGFMDVGSDDGSFKQIETALRSAAWIGQVPWLYWTFDYLSPFIGTWLGIASRHGSLRKFAAREVAARQDRGSDHQDILTKLFAVHKEKPEQFHYSDLVSMANSNIFAGSDTTAISIRSIIYHLLKNPEAKRRLVEEVDEHWRQGKLSDPITVAESENMPYLQAAMYEGLRVHPAVGMTLPRVVPQSGYDIGGYHMPAGSVVGVNPWVVHRSREVYGQDVHEFRPERWLKEDNGDMHRFFFAFGSGARVCLGRTYPDPLPALRSRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR50</accession>
    <name>A0AAD8UR50_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Maleylacetoacetate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_577703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364955.1">
        <property type="nucleotide sequence ID" value="XM_060505048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR50"/>
    <dbReference type="GeneID" id="85388947"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000010">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="94"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="24602" checksum="5396DBF22C80E1A4" modified="2024-05-29" version="1">MSDPDYILYSYFRSSCSARLRIALNLKSIPYTTIPTNLLKDEHLSDTHRALNPSASVPLLVNRSDADFKVTQSVAALEYLEETHPSTTPLLPKDVKTRAVVRSLVNIVACDIQPVTNMRIMRRIRAMGGNAEQWNRELMADGFAAYEAVAEKWAGSCSVGDEISLADVCLLPAYWNAERFGVDLSPYPTMRKIAEGLKGNPAVVKAHYFNQPDTPDELRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR64</accession>
    <name>A0AAD8UR64_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase II holoenzyme cyclin-like subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_278235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365916.1">
        <property type="nucleotide sequence ID" value="XM_060502113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR64"/>
    <dbReference type="GeneID" id="85386012"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20546">
        <property type="entry name" value="CYCLIN_SpCG1C_ScCTK2-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="3">
        <location>
            <begin position="277"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="202"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="605"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="225"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="652" mass="73281" checksum="6CF3292F65A9CC2D" modified="2024-05-29" version="1">MKFPGIIPAEMTTLNGYYVRTNSSIPGTSEIKQLDFTVDGHPKLIRVLHRQDRSVEPPRFRLRVVEHPNWVTRSVRKRKVDWDAAVDVGPAPFNHPTATLPDIYKAVLETLGREISEATLEQINNLHKDDTTLDLPLEGDKVWFDDYSWIQLPINRSSYLAISPDDDSSGDSGDSGTVGDNDCYLDCDFDCGDAFADENEQTLQGDSDTAGKDCDDNYTMAPSGPKAQSVAQSAAATNNSAPAPEPAAAKGPHPGHMQVSCQFTSEQRLRRMLRDNKSDPAREDSYRLQGVQLIDNVRTMLRVPIKTFDTACVYFHWFRLSFRDAEYNYSDAAMACLFLACKVEDTIKKSREILCAAYNIKNPEHPTTQDDKMFEQPSKIIIGLERLVLETVGFDFRCRYPQSALLKATKKILGPQSKTVFATAMEMSVDLYKTFAPVKQTTYALALGLLELSARLLGQGVDKVEKINYADFHTTRQNVVETVLDLLDLYTQHGKSTKLGVQFDLNKFIEVKIVINSEVDNTPGLVRYAHWCTNCDGGEDENLSNGVSVLKNISFFGSNSAKRNGRNQDGTMRFVFDPDRARQERKEVEAYYRDEYEEYEVEVEVPIEPEQRGGGNNNNNHNHRDKRHEGGGGGGWGGRRNHHGRAKGRGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URG9</accession>
    <name>A0AAD8URG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_573218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367095.1">
        <property type="nucleotide sequence ID" value="XM_060504598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URG9"/>
    <dbReference type="GeneID" id="85388497"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042207440" evidence="5">
        <location>
            <begin position="22"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="66"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="519" mass="55471" checksum="981E936FB3C9E191" modified="2024-05-29" version="1">MVLKKYLGIAALLGLFDQALAQPNTTSSGFKACDALIDAGLGEFLVFPTDIAYTESTSTYYSSENRRLRPYCIVQPRSTEDVSSTIKALGGVSGAGNWDVAIRSGGHSDYDNNAAHRGVTIDLTFFNSTELVKSSCFNGTANWVGQSVLTKNIAQIRPAARWGNVMTYLEPYNLGVTGGRSGHVGVGGLLVSGGASYHTQLYGFSCDNVVGYEVVLADGSIVEANTEENTDLFKALKGGGSNLGIVTRFDLRTFTVPPTGAYGGLLFASWSDLDVVIDQFVSYASSIGSGSPDHEFVVYRSDAGNLAVMAMAVSTDGNENSTSFAPFNDITLTRDMRSKQPLSKIAATIADTGGSHYIPFSLSLQATAEIMNKAAEIFVALTQDFDAASVPVSVNFVFQPLPKNLAAVTPVNNILGFDKNLPSDSILFEARGTLAATDAEYGGVVESMMGRAIEELRAYSASLEGHSTFLYMNYANPEQDVIGSYGTENVQFLKNTAAKYDPKGFFQLRVPGGWKVSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URI5</accession>
    <name>A0AAD8URI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_610398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368203.1">
        <property type="nucleotide sequence ID" value="XM_060507590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URI5"/>
    <dbReference type="GeneID" id="85391489"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="141" mass="15431" checksum="2362D24B7A691240" modified="2024-05-29" version="1">MPRGLNAARKLRMNRKDQKWADLGYKKRALGTAFKSSPFGGSSHAKGIVLEKVGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVGLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URS6</accession>
    <name>A0AAD8URS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_775591</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endosome membrane</location>
            <topology evidence="2 12">Peripheral membrane protein</topology>
            <orientation evidence="2 12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the VPS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366034.1">
        <property type="nucleotide sequence ID" value="XM_060515449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URS6"/>
    <dbReference type="GeneID" id="85399347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15735">
        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21385">
        <property type="entry name" value="GAT_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1940:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000161">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0967">Endosome</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="16">
        <location>
            <begin position="44"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="15">
        <location>
            <begin position="194"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="258"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="499"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="536"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="659"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1725979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="738" mass="80864" checksum="935B41351A46C55D" modified="2024-05-29" version="1">MSVFDGWSWIGRQLNCSLPLMRASAPKACRRTVNWKLVTMPSGKQSQAYLREDIALNLEISDVIRSKTVQPKEAMRSLKRRIGNKNPNTQLSALNLTDTCVKNGGTHFLAEIASREFMDNLTSLLQAVGPAAVNHEVKQKILELIQSWAAATEGRLELGYIGEVYKTLQREGHQFPPRISVSSSMIDSSAPPEWVDSDVCMRCRTAFTFTNRKHHCRNCGNCFDQQCSAKSLPLPHLGIMQPVRVDDGCYAKLMDRSAKGGAAPPSPLPQDRSPTYPYKTRSTSAMQPRNARVDDAFDEDLKKALAMSLEEVKGYSQGYVAPTANGPSGPKVNGSSAPAASSGADEEDDDLKAAIAASLADMEEQKQRHAAVLKEHTSNPGPNPTQQFSLPKNDYELTPVEAENINLFATLVDRLQTQPPGTILREPQIQELYDSIGTLRPKLARTYGETMSKHDTLLDLHAKLSTVVRYYDRMLEERLSKAYSQHAIGGGYNLPPRQSGAYPTLQGSAPGGAGPAENFYTGSQQMDYGHAPPPQAYAQHPQHTPQPQYATFDKRAAMAGPPGGPYPGQEPQRTDSWRSGAGPVPDGQYAPQQPYAPSEPPQANHQNQPGQPPGTPSTDPNASYYFNPQQPSAPPSAPPNADPNPSPYPNLQQPAQYRQSMPPQQTPTQTPAQPAQPTQQQVPPQQQSYWQPSVPQQSAHPQQHWQGQYNSGYTQESFPSAPQNAPKQPAVEESLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URV6</accession>
    <name>A0AAD8URV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Nitrite reductase [NAD(P)H]</fullName>
            <ecNumber evidence="19">1.7.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_575374</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>NH4(+) + 3 NAD(+) + 2 H2O = nitrite + 3 NADH + 5 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24628"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.7.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>NH4(+) + 3 NADP(+) + 2 H2O = nitrite + 3 NADPH + 5 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24632"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism; nitrate reduction (assimilation).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.4" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366079.1">
        <property type="nucleotide sequence ID" value="XM_060504804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URV6"/>
    <dbReference type="GeneID" id="85388703"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008942">
        <property type="term" value="F:nitrite reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015980">
        <property type="term" value="P:energy derivation by oxidation of organic compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19943">
        <property type="entry name" value="NirB_Fer2_BFD-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03529">
        <property type="entry name" value="Rieske_NirD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000007">
        <property type="entry name" value="Nitrite reductase [NAD(P)H] large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1100:FF:000002">
        <property type="entry name" value="Nitrite reductase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="entry name" value="BFD-like [2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052034">
        <property type="entry name" value="NasD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012748">
        <property type="entry name" value="Rieske-like_NirD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43809">
        <property type="entry name" value="NITRITE REDUCTASE (NADH) LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43809:SF1">
        <property type="entry name" value="NITRITE REDUCTASE (NADH) LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13806">
        <property type="entry name" value="Rieske_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="22" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="23">
        <location>
            <begin position="910"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="968"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="970"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00050114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00051413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00070300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1726024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1119" mass="123064" checksum="DFD1B0AF29CA955C" modified="2024-05-29" version="1">MAERKRLVVVGLGMVGIAFIEKMLKLDARVNEYSITVLGEEPHLAYNRVGLTSFFDHRKVENLYLNPEEWYHSTPQGSLGYHVNTRVTDIDSQAKTVTCSNGEIVPYDILVIATGSDAVLPKHTPGHDATGVFVYRTIDDLINLIAFAAQRKGTVGAVVGGGLLGLEAAKAMMDLDCFDKVKLIERNRWVLSRQLDNDAGSMVVDQVRDLGLDVLLSKRVGKIEVTSDNHVQGVVFEDGERMDCSTICFAIGVRPRDDLARRAGIKCADRGGGIVVGDDLSTSAPDIYAIGECASWQSQTFGLIAPGVEMADVLSFNLTQAKLHQPRLFKRPDLSTKLKLLGVDVASFGDFFADRDGPQYLPPKVARKAKKEDEQSTIKTLTNGLPPAPVKALTYRDPFQNVYKKYIFTEDGKYLLGGMMIGDTKDYIKLVPMVKNMKELDMPPSQLILGAKKEGEDDGDDLTDDTQICSCHNVTKGDVVNNVKDGTCKTLGEVKSCTKAGTGCGGCMPLVTTIFNKTMLSMGNEVKNYLCAHFNYSRADLYNIILVKKLQTFEDVMREAGNDRASLGCEACKPTMGSIFASLWNRHVMDKPMHGLQETNDRFLGNIQRNGTYSVVPRVSAGEITPDKLIAIGNVASKYKLYTKITGGQRIDMFGAKKQDLLDIWRMLVEAGMESGHAYAKSLRTVKSCVGTTWCRYGVGDSVGMAVRLEERYKSIRAPHKIKGGVSGCVRECAEAQNKDFGLIATDKGFNIFVAGNGGAKPKHSELLAKDVPPTEVIPIIDRYLMFYIRTADRLQRTARWLENLPGGIKYLQQVVLEDKLGICASLEAQMQELVDSFFDEWAEAIKNPAIAAKFKQFDNTEETVENMEVELDRDQPRPVYWAPESAKEDFKGLKERWSSTTWQPMLPASHFFGADEIPNGISATVKRGDTQLAVWRVRGRYYATQQMCPHKRQFVLSDGLIGEEPGAADGDKCEDAKKPDSGCNGGPGTNGTNEAKRPAPWVSCPYHKRNFDLADGSCKNDEEVSIATFAVEERAGDGMVYIKLPPVEELDAALGTKKWMVKKGEAGEAPFEVLDKKIRFKGHRAKRPGVKPMGALGMEKARAMVVGGGGGCGSAPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USG3</accession>
    <name>A0AAD8USG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_259608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366531.1">
        <property type="nucleotide sequence ID" value="XM_060501984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USG3"/>
    <dbReference type="GeneID" id="85385883"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="27589" checksum="F691CCE52327276D" modified="2024-05-29" version="1">MKISGHTFIISGGASGLGQACVEDICNNGGNVAILDMNEDSGNELVSKLGSSAKFFVCDVLDTKSIEAAVQGTAAWVKESGKPVGGVIPAAGVGNPSSILDRHGEPFGLDAWDFVLNINLRGTIDLTRQALALMAKNEPSKPDGERGIVIMVASSAAFDGQKGQVAYAASKGAVAAMTLPMTRDLARFGIRVVTIAPSLFESRMTSMMSDKVRASLERSMEFPVRAGKPEEFAALARHAIENVMLNGTVLRLDGGMRMPSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT70</accession>
    <name>A0AAD8UT70_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_650927</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365960.1">
        <property type="nucleotide sequence ID" value="XM_060510409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT70"/>
    <dbReference type="GeneID" id="85394308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="17020" checksum="8762A92C6F8961B3" modified="2024-05-29" version="1">MVDLPYALDAETPLKASELQVLRAQYEKEGDMVGVQTKFNYAWGLVKSDSRNDQQLGVRLLSEIFRVSPERRRECLFYLALGNYKLGNYGEARRYNDLLLEKEPANLQASNLRQLVDDKVAKEGLMGVAIISGVAVAAGVVGAFLVRNVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUX9</accession>
    <name>A0AAD8UUX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_718324</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366815.1">
        <property type="nucleotide sequence ID" value="XM_060512056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUX9"/>
    <dbReference type="GeneID" id="85395954"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="57"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="454"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="498" mass="55343" checksum="739CA76D4B0D40F7" modified="2024-05-29" version="1">MANESLARGGCPIPFYSASLFPIDEGFIEGRLCQNLSATLQCCLPCPLTDWVYPDYFNTLTTAANWVCVASAACCLFLLISWAVLPVDKTYRHYLSICLTIAVFIMNLGFVVPLADQPEQCYNDITPHSMKSSKVCGASGAFLLLGGWAGVMWVFLRSLSLHLQICWQVVVGRNFMIFAQATGWGIPLVGIVVALVFSGVSFRFGATCHINHKNSLADFWIPLLVFAGLTVIIQFATFGYCIKVYLASLADNSASTEGSSLPTYSNSIQTMSPRQAYRRVRRVISLQWRGIAIVLIIIADVIFFSVVFVFQDNTVQAVHDDESIAQAWILCLVSTKGDRTKCLDKAKNMVVNEATITAVLILLAMNGIWLLFLLGRWAMVLGWVDLFTSCLGRNKKEFVSVDARYDVKKDTRAYEMLSRDSSAVVTPISPVKSPIVSPNSERRRTPDYFGQTARYQPPMRSFSSPRPPQTPPTWDARATYARPEDGFDDMNPLGMNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV89</accession>
    <name>A0AAD8UV89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_571796</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367971.1">
        <property type="nucleotide sequence ID" value="XM_060504442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV89"/>
    <dbReference type="GeneID" id="85388341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="569"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="656" mass="72582" checksum="8D84DD8E91F46A84" modified="2024-05-29" version="1">MRKRACDSCHRRKIQCDGAVPQCNWCKHHGMACTFNRATKVKKRVATARAGSEKDLVERLNRIEKALEAARRNQDAGVEGGGPRDESTASPSSSSAPMSTVGPDPPAADGNPDTTQGRSYDSSARAASGATVGKLHFAGYYLGDVSSYNGIPFFSADGQEWIRSRAGEDASFQTLFGMGPLWQTQHPVPIFIDFPEGNASGELPDRTVVEEYLALFRASQFGLSFPVIDFVLFQETIELAYEQPNGSPSLESVTAKACVFAFFAVVSLFQGEWNSTPEIDGEACAGAAQRLVAVILQGTNITALETVFMLGMYHLFCGHLQQGAMFQSATCRVLFMLGGHLEPGSSRPTPCQTPQAEDDHTSRVRNQLRRLFWLSFKLDKDISLRTGQPPSINDEHCDLTLPKMDWWIRSIDDLTGGSPSFFDEATITSALAPDSLQLTIIKSQISTRLYSQSALKKGDAELLRDIRELDDELERWRTSVPPSYRPTLTFPRGTAVVRKGRLSMEEIILHFEYHYLMAMIHRSSGRCRCWASGEGSGLEGVSSSQALSVQASRSTLYFLKAAIHGVEQVAFWMVVFYPMSAILTIFCNLLLQPLNPQSEEDIELLNSVPKLVESMRNRHLTPHEVAHVKIVDDFVAELTRLGKRAIAKARREQELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVB2</accession>
    <name>A0AAD8UVB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Infection structure specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368414.1">
        <property type="nucleotide sequence ID" value="XM_060510231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVB2"/>
    <dbReference type="GeneID" id="85394130"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041967103" description="Infection structure specific protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="19684" checksum="F9ADB94E3E604590" modified="2024-05-29" version="1">MRVATVIFGAFAATVAAAAGDVHLQLHKRIEPTKIIKVLEARGTPECTNAVYAFASAVTGNDPLPTPNFALQEWAATASLANGTVDPCSTISVTDSMSAQYTSWSNAVESWQTAHMSEMRAVWHECTDIPIIAAEVKSLLASGGYCSTKLAALTSEGGAKETATSAGAAPRETGMAVAAAAAAGFVYAAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVJ1</accession>
    <name>A0AAD8UVJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ankyrin repeat protein nuc-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_749373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368136.1">
        <property type="nucleotide sequence ID" value="XM_060513758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVJ1"/>
    <dbReference type="GeneID" id="85397656"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08578">
        <property type="entry name" value="GDPD_NUC-2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14483">
        <property type="entry name" value="SPX_PHO81_NUC-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="5">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="463"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A2" evidence="4">
        <location>
            <begin position="480"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="6">
        <location>
            <begin position="705"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1008" mass="111217" checksum="75B5D386B5BD41C6" modified="2024-05-29" version="1">MSQIQKRQLEVPEYAASFVNYKALKKLIKKLSATPTLSAQHDPLRSAISIDSQAALQANKATFFFQLERELEKVNAFYLQKEAELKVRLKTLLDKKKVLQSRNGVSRRSAKFTTLEEGFQQFASDLNKLQQFVEINGTAFSKILKKWDKTSKSKTKELYLSRAVEVQPFFNATVISELSDQATTSLQELGAWAEGDNVSFEPRSDHIVSSQHLLGTDEGDADTLLLDTVISGNLEALRDLLIRMRTAASSSSGSDISLMERVTRTFLAAIHEAPKETLQALLDTGLVDIQSEDDINERNCLHQAAIYGNSFVLEYGLAKGVAVSRTDVYGRVPLHYASMHGRLDMLDALTSADTSTIDLIDHDNFTPLVHSIIHGHLQCVERLLAKSARIDPVSDADHVPLNLACEHGSLAIVEMLLQHGAQIVPDAEGLYPQHLVARSGQRPELLLLLKNFGANLDQVDKLYGWTPLVHAASEGNVPCLQGLLDVGADPNIVDEKDLPAMYYAVWEGHLECMQLLAPYNARTKASPMIMQPGLGPMMSSGPDPMALDPDAIPELELPPPIIPLRRYGHNFLDTKTVIQISFEENGDQPLVFFHDGKYPAARLTISSKVSDLIPKNIMLPFQEDTRIVSFQIDNLESFTLDFDVFPTYGAKIIAKTVALPNTFKALLSSSGKCCLPLFDPRLRAIGQISFHTQVIKPFNGKPLEITDFETYWKATSQFDRSPSTFVTGSSLSGDFVQLFVQHTSDGVPVLWPRWTIPCGGIDLPISRLTMEQFNTITSKSSSRAELASLPTRPLDAIADVHRVLATAGIPLNEALALLPHGMHVNIQILYPSLDEERSLGLGPSLDLNTFVDSLLTIVFDHARAQRAQSLESVRSVVFSSYNPSMCTALNWKQPNFPVFLCNDLGREDVMAPPDIIQSHGRRSASIKEVVRVAQGNNFMGLICCSRLLEMVPALVDAIKSHGLALVTDKSLDPSSTNSLTDPFPRLPKGVDGVLKSHGVLRFNESIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW02</accession>
    <name>A0AAD8UW02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368104.1">
        <property type="nucleotide sequence ID" value="XM_060504404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW02"/>
    <dbReference type="GeneID" id="85388303"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="16159" checksum="C60F62321CB2CE68" modified="2024-05-29" version="1">MPPKSKTVRPAQENISLGPQVREGELVFGVARIFASFNDTFVHVTDLSGRETICRVTGGMKVKADRDESSPYAAMLAAQDVATRCKELGITALHIKIRATGGNGTKTPGPGAQSALRALARSGMKIGRIEDVTPTPSDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7R1</accession>
    <name>A0AAD8X7R1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_724967</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000252">
        <property type="protein sequence ID" value="KAK1705018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357520.1">
        <property type="nucleotide sequence ID" value="XM_060512709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7R1"/>
    <dbReference type="GeneID" id="85396607"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="386" mass="41426" checksum="234ED08222FFD9AB" modified="2024-05-29" version="1">MTTAACSSFAGLASVRFLLGVTEATISPGFVAVTGMWWTRQEQAGRSALWVSFLGVGSFVGTMLAYGIGHITGSLSPWKYIFLILGAMTVVWGVVFTIFVPDGPAKVTWLTEREKVVAVQRVAENQTGTGRSRTFVRAQVVEAAKDPAVIILGLISFVNAIASGGLAFGSLIIQGLGFSPLNTTLMNLPLSTVQVVTQLGAGFLSSKIKSSRLHVATVAMIPPIIGTCLINQLHADNKWGRLVGVWLLGSYPVGFMVILGLLSTNIAGSTKRSVASGWVFVCYCVGQIAGPQFFKSTEAPAYHSGIVAMLCGFILNLVLNQILRFIYVLENKKRDRMLEGKSEEEVKEMRREGEVLGFEDVTDKANGDLLAVGRNWEAGVVGAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X829</accession>
    <name>A0AAD8X829_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_658240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000260">
        <property type="protein sequence ID" value="KAK1704657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357458.1">
        <property type="nucleotide sequence ID" value="XM_060511021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X829"/>
    <dbReference type="GeneID" id="85394920"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1704657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="168" mass="19140" checksum="8162A1106E952EC8" modified="2024-05-29" version="1">MLRRNTHTSRLSPEHSRFWGSRNSANCFGSSHIFDFKLLGHGSVHVSWATDTRHYTFNQVFHLLLLWSWHSVPGAAGTQHTSLIHTLGLRLGTRELSLLLSSCFWGSRNNQHFSLMLTLGSRLGTRELDFHLSSCFWGSRNVQHSSLIHTLGSRLGTRELNLLLSSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8U0</accession>
    <name>A0AAD8X8U0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_591668</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1710008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358704.1">
        <property type="nucleotide sequence ID" value="XM_060506458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8U0"/>
    <dbReference type="GeneID" id="85390357"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF84">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09170)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="47"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="475" mass="53009" checksum="6CB268EAD0213475" modified="2024-05-29" version="1">MERVLTGGSNGGPEKPVAKIGKVDEFGAHTKTDPKEIALVKKIDFYILPILWIMYFLNFLDRNAMINGKLNSLSKDLKLKGTEYNTCVSILFVGYLCGQIPSNMILNRVRPSWYMAGFMLTWSIISLLTYLAYDYKTMLVCRFFLGITEAPFYPGALYMLSMFYTRKEIATRMAVFYTGNMLASAFSGLIAAGIFAGLDGKHGLAGWQWLFIVQGAVSIGVALAAFYFLPDAPLQTRWLSLEQRQMAHQRIFDDTTDRREGGTSVWKGLREACTDWRTWLFCLMDNLHLSANGFKNFLPSVVKTLKYNTTITLVLTCPPYILAGIMSIVVSHSSGRFNERTWHTTVSKLIACAGFAMAVATLNTTVRYVGIMIFVGATYGVNNIILGWTSATLGQTDEKKAVAIAMANTFGNLASVYTPYLWPDSDEPRYLTAMLASIGFSLGVVVCAWIMRIALQRQNRKTLASNPDAMNLYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X927</accession>
    <name>A0AAD8X927_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AttH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_122446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359004.1">
        <property type="nucleotide sequence ID" value="XM_060501158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X927"/>
    <dbReference type="GeneID" id="85385057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="entry name" value="AttH-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010791">
        <property type="entry name" value="AttH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053112">
        <property type="entry name" value="Fungal_Dehydratase/Hydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40617:SF1">
        <property type="entry name" value="ATTH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40617">
        <property type="entry name" value="TERPENE CYCLASE ASQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07143">
        <property type="entry name" value="CrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17186">
        <property type="entry name" value="Lipocalin_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042119864" description="AttH domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="AttH" evidence="2">
        <location>
            <begin position="135"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="349" mass="38047" checksum="35D7E69EE698381F" modified="2024-05-29" version="1">MSWLLVFSVLASGCASELFSPDNHSTYLNTRVPSLYNLTVDQTSGSYWTSAFLTTTTGTQYLALSHILGPICKSSLLNLDTLEYKNHLEYGATSQNSSASTSQNAAASLSTGTGFQISAGNGVCALGSTSADLISEMYTTGSTPDYAYNLTWQSTSKVLLNGGNGAFTFGPGFANSTEWSIPASKTYGTLTIGNSNETLEIDSSKSMIWYDHQKGAGAPQKWTWFQLHFPNSSTKASIWSYDFGAPSYQLYQFATARVGEESQYVLPFDMETRGCGGWTSPKSNITYPQHWEITFENGDVLDIKSIREDQEIYGSQQLSDTVYAGYVNVSGKFLGEEVGFGVVEMIQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9A1</accession>
    <name>A0AAD8X9A1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_639186</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359244.1">
        <property type="nucleotide sequence ID" value="XM_060509409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9A1"/>
    <dbReference type="GeneID" id="85393308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000528">
        <property type="entry name" value="Nucleoside-diphosphate-sugar epimerase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1711920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="33414" checksum="8A0651A58B8C6CD4" modified="2024-05-29" version="1">MAQAILVCGATGKQGGAVINHLVEQNADFEILAVTRDATSGSAQRLLKKSSKIRLVQGNLADPTALFKTAQDVASSPIWGVFSVQVPMGFGQGGGGELGQGKALVDASLKAGVKFFVYTSVERHGADNATNVPHFAHKHEIEQHLFNKSKGTDMEWAVLRPVAFMDNLTDNFFGKVFTTSWRMALKGKPLQLIAVSDIGYFGAEAFLHPEAYKGRGVSLAGDDMTIEQFAAVFKSNTGKELPGTYRILCWLIMTMVKDFGYMFKWFYDVGYDVDIAALRKEYPGLKDFETWLKTESEYASRIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9V4</accession>
    <name>A0AAD8X9V4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_724304</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358436.1">
        <property type="nucleotide sequence ID" value="XM_060512643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9V4"/>
    <dbReference type="GeneID" id="85396541"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1708918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23388" checksum="18347962BBD73C6F" modified="2024-05-29" version="1">MSLKSLKSQLRGPSLGLFAALCVCLVLNLGALFFSFRVLTRGTQSYTYLEGDRPHELPIKVRTIQAEFVDDPEHYGMEGFASTVEWNAIRPPGKGFVFLGQEHFAFGVSMWHQMHCLSHIRAVLVNGDDGSDHTEHCFHYLRQGILCAADTTIEPGGTNKKLPNGDKVAAGDGAKHTCRDWRQVHDWMAEQHSKWTPEMFERINESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAM5</accession>
    <name>A0AAD8XAM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_775704</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000361">
        <property type="protein sequence ID" value="KAK1701590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357011.1">
        <property type="nucleotide sequence ID" value="XM_060515451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAM5"/>
    <dbReference type="GeneID" id="85399349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098717">
        <property type="term" value="P:pantothenate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="61"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1701590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="463" mass="50880" checksum="85850E9D93CC7062" modified="2024-05-29" version="1">MLKMKASKIMSTDKRSAGEKVRSELRCAMVQSLPWNQSDRSLAAFFLGEGAKTKEERRLTYCCLSYFFNFLGTFACQVIFRFTYLPTDRAAFANAYVSQKRLPNLSKVAGLREALHMSGHDYNTVLSVTTAGMAIGQIPHGLIIQKVPPRIWLPSMVVVWAALTMVSATVKTVTQLCVVRFFLGLAEASTYAGTIYIIGSWYTPSEIAKRTAIFTASGQVGTMFAGVMMAAIYKGMGGLGGLGGWQWVFLIDGIITLPVAFFGFYYFPDIPENTRALYLSDSEKKLAVSRLPPIKEGGHSINPISLMKRLVMSPTFWILLFWSPVCATLEAWAVQNNFLIWLKYQSSHFSQSQINTFPLGVQAVGIVSNMFAAWHMDVTGTRIPMATLAIALQLVCAVLLIVPNIPFAGTFFAFYLSGTVVVVDLWARAYCESGGSATVASSPALVDIRVGRTLALCVWSLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAR3</accession>
    <name>A0AAD8XAR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_723632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359426.1">
        <property type="nucleotide sequence ID" value="XM_060512582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAR3"/>
    <dbReference type="GeneID" id="85396480"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="129" mass="14076" checksum="4F87AE1997969D45" modified="2024-05-29" version="1">MAYSFTEEEKRFILAEAIKNSSLDVGPLVGFLKTHNVEPDWLKMQLPSGRTMGQCLAVTEQMFQGPMRVPDLKRKSINDLLEQPPKRLAAASPMEPPAQLPPLASATQGLATYSSSMPVSSAGHESHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB54</accession>
    <name>A0AAD8XB54_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_632919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361254.1">
        <property type="nucleotide sequence ID" value="XM_060509001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB54"/>
    <dbReference type="GeneID" id="85392900"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF13">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN MOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="624" mass="70049" checksum="5DCAE8ED8AFA1FC8" modified="2024-05-29" version="1">MENHLGPDLASKIGPWILPKPLEAPPSPESVCNSDRASPTEETKRRRAGGPKARTGCATCKTRHVKCDERKPTCFRCEKVGVVCEGYVDRIDRRRKRSNQNVVRRNTPRLIAPRSASAEAADMSSGNSSSKSDMILSPQIPKSLSSLPKIYHKDGVYYDYFRHQVSTNLAGYYTSPNWSYLVVGEGLQDDCIHHSILAVGALIRSTPQDARPSTPRRKALPPASDGYAVTEHREVALRHHLKAVKSLRERMELITASSPTTVVVTTLLLVVYELLQGEPRTAEMLLNSCLGALRDSITMFESDPDSEEKYRDSEFNDMEHVLPCIAAMSQLSQSLQPRRHHAHPFKIDPGSDVHNPHHEPISKFFISWGRFFTFAVSFISNSTDVTAEGISMDMLRHLTIHQQNFLSQLQQWRSVIQYYAESPRVDIATKKGLRIAQIHWLLLHITLTCCLDPTEVAYDAFENEFRDLTMLCVELYRDCVSQPRPTSVLLGQGLILPLCTVVRACRNHDIRMTALQALHEIPPSMVAWDVVSNMDGILGALLLEETGRDPAGFVPPESRWFWLKDVTVPETQRIHKVYQRLAPGQDGKPVLTKLRPTSNVRSKICKASGCEKDHLLGPVVVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBR0</accession>
    <name>A0AAD8XBR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_724078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358778.1">
        <property type="nucleotide sequence ID" value="XM_060512622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBR0"/>
    <dbReference type="GeneID" id="85396520"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="29196" checksum="65BB4A52E5BC657F" modified="2024-05-29" version="1">MTPSRRDSWPPTLVRLAPTIPKDYPSLDDIDEDPLTYFLTPAPDLEDDEDDMTMMDFDAGIEDDSEREIVRSVSPSSLDGLDKSKGRSNSPPVPDLSDLATPDTDDEEEDYIRFAPHGFMIPFSLRDFATDGLKSMAKSKSRPSKPSDNSNVLLSPSSFPPTRGRAPVRPGGGRGRQRTTSYRHHRPQHVWREPSPDVWSIEEETEEELLSEMGSSVGAVSDMEDDQTEGDQTEAATTCPNKSGDVQAAKPKKKVRFLLPAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC07</accession>
    <name>A0AAD8XC07_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_639626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359048.1">
        <property type="nucleotide sequence ID" value="XM_060509442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC07"/>
    <dbReference type="GeneID" id="85393341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF8">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041768791" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="61498" checksum="A42560FA24127EB9" modified="2024-05-29" version="1">MMMASMQTSSPLARLLTWLAWGAASHPFALATEHHPNTFRKCMGDLGGSASDGKPGSSLGIGGQRVLGLPSKGCVDPQPLTCNKLEIPPIDGFDVIVTESNEVHDYVLPTDPNSKIDFCNFTLTLNHHGADDVVFVSMWLPLADTWNGRFLATGGGGLAAGTFASALAGPVSKGFAAGSTDAGLTLNHTIDANSGQWALRANGSINEPLIENFATRSIHEMALIGKEAVKAFYGTKPHHSYYSGCSQGGRQGYFAAQYSPYDFDGVLANAPAINTPQLSPADFWPSVVMGNIAAPPQCVFLEYQKAIVAECDPQDGAKDGLISAPEKCQFDTSQLIGQSINCTDTGGPVVITEDLAKVVAKTLEGSRTTTGNFLWYGNPPGAPFTGLANTKTVNGVTVPVPFAAAEAWMRYFVAQDPDLDTASLTFAEFEEIFNESVAKYTKPFGSDDFDLTEFKQVGGRLLTWHGMSDPLITHLGTTLFWDKLQERIGGVESLKSFYRLFLAPGAGHCGGGYGPVPVEPLSILVDWVETGKAPDTLFAVTTQDGINTTRNLCPYPQTIKYKGTGNMKDATSFSCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDI2</accession>
    <name>A0AAD8XDI2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF952 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_794487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362336.1">
        <property type="nucleotide sequence ID" value="XM_060515816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDI2"/>
    <dbReference type="GeneID" id="85399714"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14178" checksum="FCA9CCA1CA119974" modified="2024-05-29" version="1">MAEPAQTPQYIYKIVPEAPPSPLPTEFPLSDLDRNDGFIHLSTAEQVLNTANLFFSSATTLYLLKLPYAPLAASGSMKWEFPPSGKFPSAFPHLYGRNFGAADVEDAKGFERAEGQVWSEVLGGDEWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDX0</accession>
    <name>A0AAD8XDX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C6 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_579264</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364239.1">
        <property type="nucleotide sequence ID" value="XM_060505216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDX0"/>
    <dbReference type="GeneID" id="85389115"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF24">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="60428" checksum="64405C4D5F9AD745" modified="2024-05-29" version="1">MANDDESTAAPLDRVENPGSQSQPQSHSQSESHSHCHSHSHSHSHSRSHVRSHSQSQAFSHFGSAVTPGASSTWGLGEPTPSHHLSSEASTSPAESWRLDEFVTDPGYLAYQEELRCLIFNTAQTAAPTREGTPEAADGGFSAGGFAAPGTILGDEGAARRQAGQILGTGRRLEYLKNYVGEVATWLDMFDSDRAFGIQVPVLARSSPALLYAVLALSARQMERKEGKQTSFDSLELYQEAIRLLTPLLQSRDQKIIPICTILCCLEMMSASAQDWRKHLEGCAALFESFYVHGFSGGLLQAVFWCYARMDLCGALISDGTESTLLTPSKWLPSGASHNEASELFHQSGTPDMHANYAVYLCAKVCELVADRTRYFELGDASGCSSPDELTERWIRLWEDLQAWTRDRPPELLPVQSIQSSPFPQILFLHWAAISSNQLYHTACTLLLGSMPRPLNLKLGGVTGSAIWHAKCICGISLANPHQGCLNNAIQPLWVAGRLLSHKSEHALLVKLIRSIEAVTGWGTCWRIDDLEAAWGYKVRKELRIADMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEI8</accession>
    <name>A0AAD8XEI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferric reductase transmembrane component 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580791</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363446.1">
        <property type="nucleotide sequence ID" value="XM_060505383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEI8"/>
    <dbReference type="GeneID" id="85389282"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="570"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="281"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="617" mass="69384" checksum="15126A66093AE12E" modified="2024-05-29" version="1" fragment="single">MAGGVIAEEVGIAGHGLIGYGITMYQPLCAYSCRVALSASPLNCSNVMEIHGMIMADTSPECYANDNVFLTSFAWCIHTRCTDLSIWEIEKYWQSTEASIRNSHRRLDEPGVNVNAYPPAPKWTYQEAFSNVNGTPTATVVFAMPLKEKSLVSDADYQVQYNTMGMFEKMEVAHERYGLVLIALGAAVPIFFSWLRFIPLPKLVISKIHAVFIDPPLFGRRHKAPYFNLLIMPTRGQAILVFYMVAVNVVLSGVGYDSAQPNAWWVNDKDQELLTSFSNRMGVLSFANLPLLILYAGRNNFLYWVTDWTQSTFMLLHRWTAYFCTLQACLHSAAWLQIYVSMGQHDIEAKLPYWVWGIIGTLAMSILLPASVIPFRAKLYELFLAVHIVLAVFAVVGSYLHIVYRFQNQWGYEIWMYICFAVWGFDRVARVIRMARNGLMWADITIIDEEYMQLDIDGAVGSGHAYLYFPTLTWRPWESHPFSILASRVKPAPAKSMNSIMPTQSSVNSYSKESSVMEVAAVKEKSRVGLSFLVRSFTGATELLRSRTRVPVFVEAGYLPHHDLSKYQKLVCIIGGVAITAVAPVLQTYPGNAKLYWSSRTEGLVQSVDLNGIDANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEQ6</accession>
    <name>A0AAD8XEQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_586443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360955.1">
        <property type="nucleotide sequence ID" value="XM_060505951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEQ6"/>
    <dbReference type="GeneID" id="85389850"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="59234" checksum="1646539C0607BB6B" modified="2024-05-29" version="1">MTRLGPLTAQALGRSPFDDVVDGEGEDDPHAPTQQYDNRGRPVNPETKRMNRDMVRSHNEVMQVIGVAEPDNTPSTAEVDSVRRYFNYEDAVGTRLLRFGRALEIAGVWGINGLRLRILLYRRYADISFFELFQHERRQRSISSALLTGLPTFLGGHVFKMATYWFYPYPRKNKFVNTALSYIRVHLQLYVFLQRLDIIPSARWFPSLSFFIPGSPSSPIAAPAPPKDLSPSSLVHYAGAWCVNSIPFISYVIWGQIWTEVTGHLWQEFYGRLPNTVHHRKPPPPPPPLPPVTIPETPEPVPDVDRQQPEPLSELRSEDILEDTPPEAEPSDTPPVQAVRRPSAFSARGEDYGSDDEEDGGISATLISFDVEATDSTDAPPGLWSAELRPSTGPEGSGYGAAIQYMDTMLTRLPACLASDIFTVISGYVLVSPYEAVALRLVARSYRERMGLPTFDIHDTNIFSGMTLRGVTNFLGLEFLHLVIAGELWALITGLAQWFHITEEEWKLWNEIEEAEAAEERRRQGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XET0</accession>
    <name>A0AAD8XET0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enolase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_578384</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364642.1">
        <property type="nucleotide sequence ID" value="XM_060505117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XET0"/>
    <dbReference type="SMR" id="A0AAD8XET0"/>
    <dbReference type="GeneID" id="85389016"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="15">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="14">
        <location>
            <begin position="143"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="374"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1724587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="47365" checksum="48083E32B55C7A7B" modified="2024-05-29" version="1">MAITKIHARYVYDSRGNPTVEVDVVTETGLHRAIVPSGASTGQHEACELRDGDKTKWAGKGVTKAVENVNSVIAPALIKENLDVKDQTKVDKFLIDLDGTPNKTKLGANAILGVSLAVAKAGAAEKGVPLYAHVSDLAGTKKPYVLPVPFMNVLNGGSHAGGRLAFQEFMIVPSAAPSFSEALRQGAEVYQILKSLAKKKYGQSAGNVGDEGGVAPDIQTAEEALELIAEAIEKAGYTGQMNIAMDVASSEFYKEDAKKYDLDFKNPDSDPTKWITYEQLAQQYSDLAKKYPIVSIEDPFAEDDWEAWSYFYKTQDIQIVGDDLTVTNPLRIKKAIELKAANALLLKVNQIGTLTESIQAAKDSYADGWGVMVSHRSGETEDVTISDIVVGIRAGQIKTGAPARSERLAKLNQILRIEEELGENAVYAGANFRKSVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK0</accession>
    <name>A0AAD8XFK0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CVNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364481.1">
        <property type="nucleotide sequence ID" value="XM_060514233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK0"/>
    <dbReference type="GeneID" id="85398131"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42076:SF1">
        <property type="entry name" value="CYANOVIRIN-N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42076">
        <property type="entry name" value="CYANOVIRIN-N HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="1">
        <location>
            <begin position="3"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="12304" checksum="41A8AD6CF7662A44" modified="2024-05-29" version="1">MSNFHHSAQDTRVDDGHILRARLQNGNGDFVDAEINLNDCLGNDNGRFDWGGRGFADSAENIRFEFEGDQPILRARLFNVEGQAIDADVNLCERLSNSDGNFHFELFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK8</accession>
    <name>A0AAD8XFK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_721917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361750.1">
        <property type="nucleotide sequence ID" value="XM_060512421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK8"/>
    <dbReference type="GeneID" id="85396319"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928459" evidence="1">
        <location>
            <begin position="26"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="340" mass="36525" checksum="628F203D05BE8493" modified="2024-05-29" version="1">MRLSFPSLMGTSLLTVLTGSGPALATVPILTEVSLKGCADVDCPPGAVDDLVGESNCTLAGSVLRRVGIAPEVLDIPIDDNNTTDIRKLSLTVATLANSPAPANSPSWIKKQLYTQSYYLGAPAGLNLSSESYPKGCALIFQHMFQTLPTPHEVPDLDTTDCSSWLQQSCMDEITGYVDDFRAAHSKDETLPRCQEIAMYLEERTRTDKDFHCNLVAGAVNITGVDVIGPDAPTVLAQDAGDADDNNDCHPTLPQSYDMYKLTDVELILDGDGSTTKPTGGLNGYTPVMSVLFDKLLYSQWICMKTMSEYDQENASARTSTPVVAGLIMGLATLVAIMML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFV8</accession>
    <name>A0AAD8XFV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_626999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363293.1">
        <property type="nucleotide sequence ID" value="XM_060508600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFV8"/>
    <dbReference type="GeneID" id="85392499"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003191" evidence="1">
        <location>
            <begin position="21"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="16385" checksum="9790096C8F43A4EB" modified="2024-05-29" version="1">MHSFPTVLLFIAALAGHSVAQSCTDQCADVFAVASSECPHLGNTKEDADTLNGPKMSWKNNIWSTRGRDGAVVEIDPRACTLRTFGGRDDFCGIWIGGKEEKGKGNAEVKQPNALLQIPFNGGCCKIDKEFCKDGAIDWAQLLRVKKGPDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG57</accession>
    <name>A0AAD8XG57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_625901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363623.1">
        <property type="nucleotide sequence ID" value="XM_060508519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG57"/>
    <dbReference type="GeneID" id="85392418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="25190" checksum="F996F0E1A22AC28B" modified="2024-05-29" version="1">MSIHPRCAGDVTFNTLASNAFSEWPESIAGIICKTPPVGRNSAPHFADCCSGTVYNITSPTSPDNKAYPVSCATFCQISPKMNADNVNNPYGFNDHFMCLTDGTREPSSWEVVCATVTLPGVAWPSTFPSTPVLSWKTRSWTTDIYSRISEVTSVVYSQTASPTPTVTTDIAITSSSQRVSISTSDSSATSTSPTTASSTQTSTVVATPTGSGAADGARIHAKQLMLSVLLLISALCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGD3</accession>
    <name>A0AAD8XGD3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">EXS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_616875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366292.1">
        <property type="nucleotide sequence ID" value="XM_060507999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGD3"/>
    <dbReference type="GeneID" id="85391898"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="190"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="406" mass="46423" checksum="BF68A47BEE79DFEF" modified="2024-05-29" version="1">MDGDPKVESQLDSFSLTFPLPYRIGFIIVLAVWGWGVNLHYLHKVKIDVPSLIRYPSRSSPTQPAHHLSTYRLATVLSTVFLLSISTFWIFSRRTPALVIEYDWLPMTYLVALAALFFVPIRNFSQGGRSRFLATLRRVIIGGIAEAKDGKFGDILLADVLTSYSKILGDLYVILCMFFTPSGSSTARPDRNCGGTVIVPLIMAVPFAIRFRQCIIEYFRVRRAPYKESVGWGGQHLANATKYATAFPVIIFSALQRSVPADQPAPGLNRAWLVAVLVNSLYSWYWDVAKDWDLTLFSSARERNNPEHPFGLRRRLVFQQPVIYYAVIGMDLMLRCTWSLKLNAHLDKFTDFESSIFLLQSLEVFRRWVWIFFRIETEWLRNNTSGLAVDDILLGDYQGKYDSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGU0</accession>
    <name>A0AAD8XGU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_359326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364358.1">
        <property type="nucleotide sequence ID" value="XM_060502566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGU0"/>
    <dbReference type="GeneID" id="85386465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="277" mass="31549" checksum="069DC3204F52EB91" modified="2024-05-29" version="1">MNGSLTDLVSIFIYDRWFGISLISALDLVNHLCLLTLDGELGIAPPCREDAKVGRVLDVGTGTGIWAVQFGDDHPEADILGIDLSATQPSCVPPNVRFEVDDIEDEWTFSQPFQYIHSRFMTSSIRDWRLFLQRCYDNLEPGGYVELQETAIFAQSDDGTLKPEHALSNWSKYLMEASIKLGAAWVDTPELREIMVEVGFEDVALSTYKWPTNTWPKDEHFKELGSWNNENFMTGIEAITMAPLTRALDWSPEEVRLFLIEVRKNGNDRNIHAYWPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGY1</accession>
    <name>A0AAD8XGY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_618038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365951.1">
        <property type="nucleotide sequence ID" value="XM_060508054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGY1"/>
    <dbReference type="GeneID" id="85391953"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="91" mass="9641" checksum="63082702EAFF7803" modified="2024-05-29" version="1">MATENFTTKPSTRVVMGYHFWLTAGSYSARDRSAPESVCPLLCGLSGLQGGRVPEKPAGDIGGSLGSWRNSQESRGGCRLKPQCGLLPVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH26</accession>
    <name>A0AAD8XH26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_276926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366086.1">
        <property type="nucleotide sequence ID" value="XM_060502102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH26"/>
    <dbReference type="GeneID" id="85386001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="854" mass="96840" checksum="4495F76DAC45E10C" modified="2024-05-29" version="1">MFDHLRDKDGMIQYIGWYQSLETDNEGAQREYHYIILELGDSNLYTAIRTLEPPVSPKEILGFWTAMSGISEALASIYKLKLGGVNYYTWHADIKPENILRVDSRYKLADPGEAYIQLSNGENRRQSARVTGGTRTYGAPEKAAYLDGRSLQEPLITQTSDVWSLGCVFSIAATYVVLGPQGVLIYDRIRRAGILEKTGDVSDTFHHDDKVLSEVTEWHRYLRAVARKTDAYTADVLDMVDQYMLVAAPDKRFTAVQVRDWFKRRLEQSLIPTREVPSRIEDLLQDIELEVELDYEQHSGIKRLDSNMVPKRPASRNAQASTEPDFKSQKELLDQGIRPTAHRSARDSPPKPPTLTIDVTSDRTSWTPKYPVAHDSHAYHAGSFGGQHLHTQSVVGHDTSQTPIPRAPVTMWKVMGVLEEHGHGRSRSLVKFGSFGRKKKMSVKGKAAWKTASLTEHLNERLEKEFENRDIVYLVDNGTSMREHWDQATFILGGLVWRSLGYDENGMELCFTNPDTNPAAHIRESPKQEVETFTEAMKLAKPSSNDKMPVETMIVPELARIINDYSRAMISKRRPKKKTIIVLTDGVWNGMHIPNTLDEHLKAVFQLLRDLHKDLPLRNSPHNQGQEDIEKIRPITIQFVRFGTNELGKERLRHLDDDLTNYGCPDLIDTEPADGDVYKMFLGSLCDDIDRQQSIVYEPALTMVTSPSTVSDSMPIGLSREPTQEREPAHHRDSTPISPNHRVLEASHYGEQFSPTSGRFQETSVTSPLSLYPQELSAPQYETRSNQDHVSPLRISLPQHSTNPNFARHDNQLQQRSPMTAASWGMRTEAGHDQSSSHPRAEAPYGYRNSFHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI44</accession>
    <name>A0AAD8XI44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathionylspermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_751608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365618.1">
        <property type="nucleotide sequence ID" value="XM_060514074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI44"/>
    <dbReference type="GeneID" id="85397972"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathionylspermidine synthase pre-ATP-grasp-like" evidence="6">
        <location>
            <begin position="15"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="53839" checksum="378B0FFEDC0733BE" modified="2024-05-29" version="1">MRRVPVQKRPNATRLVQSQGLVFADLVAPGASEPYWPDDRYYSFTEQEMNLLEEAARDVFAMCCEAADYLVEHPDIITKKMAVPAFALKQIKASWDREPAWGSIYGRFDICFGGLEHPDPRLRVPKFYEFNADTPTSLLEAASIQWLWMEQTGHGNDQFNSITEKLIEGWKRNMTLVEKELGHKPTVHFAVGEGEATGEDAMNTMLLMETCQQAGWMTKALTMEEIAKSKKDGRFYDAQGEHIDVIFKLYPWEYMVEQQFGEACFEDMENIGKRDEVGNYIGGTVWIEPPYKLLWSNKAVFAVLWDMFKDDPRGKWLLPTYFDNEAPASMTSFARKPIFAREGADVVLKKDGEILQDASTGDYGAEGYIVQELAVLPEFKDAKGSSWYPVLGMWFVDGDPVGMGIREDGTPITTNASVFIPHSIEDGPVNYMRQKIPDQEEIENLLRVEPFFDSFDKEENEMMSYIKKIVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIB1</accession>
    <name>A0AAD8XIB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_575858</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365888.1">
        <property type="nucleotide sequence ID" value="XM_060504862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIB1"/>
    <dbReference type="GeneID" id="85388761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000199">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048867">
        <property type="entry name" value="WHD_ORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21312">
        <property type="entry name" value="WHD_ORC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82061">
        <property type="entry name" value="BAH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="12">
        <location>
            <begin position="80"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="230"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="575"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1725833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="751" mass="82890" checksum="144E828DBB860C2B" modified="2024-05-29" version="1">MGVSAPQTAPRGRRQSKKSTGVIRDDSDDELGIDDLPWEWILESNDPHTAENHGDDTQTSRKRRRANTEARIMGARMGKFECYVGDCVLLKAEGSNEAWVAVVCEFLEEEDGEKAANFMWFSTEKEIRNKERKRSDFLPNELYISPSWDVNPLAAVNGTAVVISHQAFHQRYPSGKIPRSSPDFGKTFICRRACNTRTATYTDEFVWEEVYHASEQGVSDLIGFVKSHTKSTRHGQAARQSTPEQSYKMTSDRLAGASTPKRTPKAEHSTPKGDTRITTTPGSRASPNRPCSCRIVVKKTLEFTPLGTRKLSPKRLQSSPFQLARSQLHVASVPRSLPCRESEFNLVYSHLEAAIADGSGSCIYIAGTPGTGKTATVREVISRLEDSVKADELDDFIFVEINGMKITDPHQSYTLLWEALKGERVSPTQAIDLLEREFNNPSPRRTPCVVLMDELDQLVTKNQSVMYNFFNWPGLRHSRLIVLAVANTMDLPERTLSNKISSRIGLTRITFPGYNHEQLMKIIQSRLECVPGSIVEADAIQFASRKVAAVSGDARRALDICRRAVELAEGDTRVETLAGDPEARRSTPSKGRPTEAPVKVTIATVKRAINEATTNPVQQYLRSLPFGPKLFLCALLVRIQRSGTAETTFGDVVDELHRIIKLDTANLESTVLGALSTGPPGGDGGQGNGSIRVVQSLALPQAALELMGAGIIVLEAHKSERPSKVRLAVGDEEVKMAFRDDGEVKALGLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIH2</accession>
    <name>A0AAD8XIH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3 11">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_622015</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3 11"/>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364690.1">
        <property type="nucleotide sequence ID" value="XM_060508306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIH2"/>
    <dbReference type="GeneID" id="85392205"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000001">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.50:FF:000004">
        <property type="entry name" value="Glutamate-cysteine ligase Gcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="5 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="488"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="645"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1724635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="669" mass="75478" checksum="B3286F95D0CCCA8D" modified="2024-05-29" version="1">MLWGDEVEYLVVTYSKDEPKVRLSLRQAEILTALAESPDLAKEGGCVPELQEVAREQSSVTLPVFHPEFGRFMLEATPGKPWGIGFKELLDVEPDMKLRRKIAKDHMHSNEYPITLTTFPRIGCPGDFTEPYYPPSGPKLRSQFVPDEIANPHIRFPTLAANIRWRRGRKVQVNVPVFHDTNTPNPWKDPTVNRDLHNWPEDDDVRDGGAAPDNFIHMDAMAFGMGSCCLQITFQAKNITEGRKMYDQLSPLGPIMLALTAATPVYKGFLANTDVRWNQISRAVDCRTPEELGEKPLKNDRWRIPKSRYASNSTYISTDPRLRQEYLDPNLVIDESIKSKLMDGGMDDRLATHFAHLFIRDPIVVFEEDLQELDLSKTDHFENLQSTNWQHMRFKPPPADNSIGWRVEFRPMEIQLTDFENAAFSVFMVLVTRAILSFDLNFYIPITKVDENMERAHAVDAVLKEKFFFRRNPFPGRQVRVNNFIQGDDTATASRPGSRPGSAVPSRPPTPVGPVEDEYAEMTVNDIINGNPDSSDSFPGLIPLVESYLDSVNVDVQTRCELDTYLRLISQRASGQLDTAARWLRNLVDVHPGYHHDSVVGEDVQKDIIAAVVAIGERETAGAGFEGLDIHGLPKLLGNFRRGCGGSGEQQQLQQPEVSARKRKASEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XII2</accession>
    <name>A0AAD8XII2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_572013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367796.1">
        <property type="nucleotide sequence ID" value="XM_060504460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XII2"/>
    <dbReference type="GeneID" id="85388359"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="311" mass="34937" checksum="AD3B44BD181E3E52" modified="2024-05-29" version="1">MTAPTSGPVCRFKFTILPEYFVDYYKVADASPNGKATTQPGLGLLDMRFGDAAADDDVVAEDEARPWERFASYVRKLNAESPDGVNFKVLYLTRHGLGYHNVQAAKVGTAEWDRYWSHLDGDGAVTWLDAALVDTGIQQAKDLSTFWARATSTTAEGEGVPFPESFYTSPLRRCLETSNLAFGPLVEPKGQYFRPLVKEGLRERMTDHTCDKRSSRSWIESAYPRYHIEPGFTEEDRLWKADRFETTEEHVARKQLVLEEIFSTDAAQFVSLTVHSYAISAILMVGGQEEFRVREGSSIALLVRGEKVGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIK3</accession>
    <name>A0AAD8XIK3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Eukaryotic aspartyl protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_749620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367871.1">
        <property type="nucleotide sequence ID" value="XM_060513784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIK3"/>
    <dbReference type="GeneID" id="85397682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917847" evidence="9">
        <location>
            <begin position="20"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="58"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="53591" checksum="0F6A0A3F1CBEE192" modified="2024-05-29" version="1">MKLSTTTLALAALASEAVSQKVISANFHKIQLPVDLVQITRRDTLTLAALNNITGGGYYSEVEIGTPGQKALLHVDTGSSDTWIVDKQADLCTSTKLQRQYETGCTETYNSTASSTYKVVGQNGFDITYLDGKNIKGDYISDVVSINGKTVKDQQLGLAIQTVKGTGLIGLGFSQTVATKRKYPTILDNMVTQGVIGRKAFSIWLNDLSSSEGTLLFGGIDTEKYIGSLTTLPLVNDHHSGNMTSYSISMTGVEIETPDGKTVNMAGGNFNAATVLDSGSTVCLLPEQMAKDIWVKYDVVDAGYGFIDCKWRGPQGEGIFFDFAFAGVKIRVPMEEMVLDNLDPIMDQLKGLTPFDKPCMFGIQNSAAFDVNSTEFALLGDTFLRSAYVVYDEANHQVGIAQSNLNATRTNVIELRAGETSLPTATGVASQASTPAPTSTRAGTGTMTGTAAAGIDTSVVSAGAATPSSSESPNAASHPGLVASETDGFLVMVLMSVFAVVGAALMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK99</accession>
    <name>A0AAD8XK99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_87532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368983.1">
        <property type="nucleotide sequence ID" value="XM_060515970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK99"/>
    <dbReference type="GeneID" id="85399868"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928462" evidence="2">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="37683" checksum="B30BCEFEDFA10B2F" modified="2024-05-29" version="1">MLPFVVAALASVATASQCGLKKFENLVAFGDSYTDEGRLSYFINNNGTAPPAGTLLPPSNSTASGGYAWGRIAANSTGANYYGYAVSGATCSNKIISRDFAAIKQPFPSVLDYEIPAYKADTAFETLYPNRKADNTVYALWIGTNDLGYGAFLTDTNAAGTTISSYVDCIWEVFDNVYETGGRHFVLLNIAPLEQSPLYAATGPGKSGFGDSQFWTNKTAYNTTETEFKMFEYSTSVNTMFDYGAPFHLLVKKRWPGASFSIFDVHSLLRDVHADPSSYLSSPANVTAPYRTCDAVTRACVDSSEAKSSFLWYDELHPSERADEIIAQNFIDVVYGNSTYGTTYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKX7</accession>
    <name>A0AAD8XKX7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_569272</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369264.1">
        <property type="nucleotide sequence ID" value="XM_060504173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKX7"/>
    <dbReference type="GeneID" id="85388072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="679"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Non-structural maintenance of chromosomes element 1 RING C4HC3-type" evidence="17">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="354"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="427"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="507"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="723"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="743"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1729209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="794" mass="88265" checksum="D221C73E8C71E9A0" modified="2024-05-29" version="1">MNIVREHYNDGNRAFLQAFLARGTLTYEDAQPILAGIFTIEAQDGEPVAPEQVTMEDFDSYLRAAAEGVSFFDYEIRSTIHQVTKKRIYALVNTASDPMTQLATTFNAEQISFTKRLLDAMFETYNSPRMELMCITEMQAIKLARPPRQNNNNNDENGEPTQTQSSSDKGLKHSEVEDMLANLVNQGWLEKSKDGFYSLSPRALLELRAWLIDSFNDPDAAAQDWQRIKFCEACREIVTVGQRCAERDCNARLHNTCQEGYWRTQRSHKCPKCSKDWDGEHYVGEQAMTSTEAYQRGRRRISTKDTPRWWLTQPYHSIFANDMHTLHNAQTAMLEYLSYKKFKKYKTEKEAKEAAAAEGEVEHNSVSPAPSTGKLHPDSRPSATRRQTSSQSVSTTASAATGGGGPAPLLNRKDEAFFRRILADANDVDSDDESVRPALPPRSKTPEYIWEDSDGSRRTAAAAEKQTPKKAATVAVDPKDANASGSSSKIPSKIAFLFNKAKGTLNDKDKQLAPTKSNVPPKEAAREEDDLSRVLDDLNLSARNNKAVPLSAESSELVSKFTLVLKDLVNGVPTAADDLKALVEDRDGTLAKTFDKLPNSMKKLVTQLPDKFTASLGPEVLAAAAKAQGVNHAEFTAEEGIKGAAKKMFTPTSLADLVTKPGAVVGMLKAIVNALKLRWPAFIGANVIWSVSIFLLLFVLWYCHKRGREERIKRENAPEIIDGSGRIEELPDDPALMAGPSRSRTEPVVRSSDRPRSQRSERSRRSGRHSSGRTTPQRRASPGPDSPRRRSTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKY5</accession>
    <name>A0AAD8XKY5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyroglutamyl peptidase type I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_568826</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369345.1">
        <property type="nucleotide sequence ID" value="XM_060504120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKY5"/>
    <dbReference type="GeneID" id="85388019"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016920">
        <property type="term" value="F:pyroglutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00501">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="entry name" value="Peptidase C15, pyroglutamyl peptidase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000816">
        <property type="entry name" value="Peptidase_C15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016125">
        <property type="entry name" value="Peptidase_C15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402">
        <property type="entry name" value="PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23402:SF1">
        <property type="entry name" value="PYROGLUTAMYL-PEPTIDASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01470">
        <property type="entry name" value="Peptidase_C15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30720" checksum="DCCDB4EC9973A179" modified="2024-05-29" version="1">MGSQIDSQDEFTVLVTGFGPFKAQYPVNPSWEIAHSLPAYLPPLRAKNPKDHHSSTSPSTSSSSRPLPPVRILVHPEAIRVNYQNVRRLVPQLWDPATHPRIDATVHIGMAGPRLFYSIERRGHRDGYAFPDVDGKKLEDEDRRREEGENWVWYGMPAEIETGLDLADVLERWKDHSPEGSDLRISEDAGHYLCDFIYFSSLAHLWKAQKHRRVTFLHVPSDASEASVSRGTELAIQLIRSIAESELSRRRKGGEEEVVGKDDKIAVELRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLN7</accession>
    <name>A0AAD8XLN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_567960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369706.1">
        <property type="nucleotide sequence ID" value="XM_060504012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLN7"/>
    <dbReference type="GeneID" id="85387911"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF1">
        <property type="entry name" value="ACTIVATOR OF STRESS GENES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="706"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="798"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="799"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="969" mass="108555" checksum="17A78C709956DFF6" modified="2024-05-29" version="1">MSPPSQPAKATTNNNSNNSPPDSHASGNMSDDESAAPSANGWPVKEPPSPSGSAHSGSDMDEKPGEAGSNAPVQKRRRVTRACDECRRKKIKCDGKQPCTHCSVYSYECTYDKPSNRRRNPAPQYIEALESRLQRAETLLRKFIPDVDLADPTLDPAVQQEFRNREHSRIQSAKLRHDPFVAPEKEDPQLLSMIESIGQLDLDDKGGWDFHGVSSGAVFLRRMKEHFRGMMGPVTKVPFLPRPDRPAGLINLDSPASAASSPFDSTMSTAPELPPKEVAKSLCYLSLNCATCLIRIVHVPTFYQMFDRIYEKSYDDYTKEEHKFLGLLYAVMALGCMYRNLDENAPPVAYKESVDEGMKYYDTARRILQDITECRDLTSLQALLFMILFLQATSNLSGCYAFVGIALRSALRIGLHRYLKHEKISIIEQEVRKRVFWVIRQMDIYVSAMLGFPLMLNADDIDQPYPSEIDDEYITNDGILTPPPGTFSFFEAFNAHTRLMEILAKILKFVYPLKGLGQSVMKGDKPGATYLISYANIKRIEAELQEWYEVLPAQWRPRPDGPMEVIRVRHLLRFAYAHVQLVLYRPFLHYVSPRLSMGKNIDELSYACAAACISVSRNIVHIGIEIRKQNVLAGPYWFMLFTEFFAILSLVFYSIENPEKIGSAEVLEDAIAGRDMVSKLQSKSQAADRVTEALNVLFEQLPERLQEAKSRPIPTKKRSAPGQKASSMPVHGHPALQPGMGQRRSEELSRPSSVVMAHGRMAQVPLRASFDGVPISEAGYQDPSLASNIQDLLGMDMSSRATPDSVSTSASSTQRPPQGFPPPHNMNHISKLDSLMFPSEDPFAYPNQPMMELGYQKPGTNNVSGPQETFMMPGAFDDIDTQLLGQSPAYYLQGQSQQQQHSHHQSSYDLSSIYQQHSGYSGMPDAARIEQARRAHMQQRPAELERMLAETGYQSNWAGMLGRNGFQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMI3</accession>
    <name>A0AAD8XMI3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_647217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370093.1">
        <property type="nucleotide sequence ID" value="XM_060510054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMI3"/>
    <dbReference type="GeneID" id="85393953"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04813">
        <property type="entry name" value="PA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000364">
        <property type="entry name" value="Protease-associated PA domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF406">
        <property type="entry name" value="PA AND RING FINGER DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G02470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070224" description="RING-type domain-containing protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="723"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="423"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="640"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="778"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="643"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="838"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="857" mass="92372" checksum="F014D654164BDEAB" modified="2024-05-29" version="1">MRTPRIAILVLFFAASLFLFCRSITSLARSSPASSSSPVIAAPVAVPRSRFTSFFSFTAPFSIFQPNAAISLTDDNSTSFVARPAAFGPNLPNKGLSGQLWIGSGFADDNLQEGEGEGELGCSDIPGWDDGKANAVLKTATKGMSKSSNKAAAAAGKPGHHKRDKTDKDAVPDAVGVPVTRLRSKIRPADDGTDDYLHQGLARKPQPNHDSALSTESTHADIQSIQEAAEIAGKIVLLSRGGCGFLEKVKWAQRRGAMALIVGDNTKGGPLIQMFARGDTSNVSIPSVFTTRTTAHLLSSLTQPGSFIEDTLDEHGRPALKVLQSDGGSRKNRKNKQKVAATTPTPIPKATATPKAKAAAKGKPAKAEHKATKPRTSLFRWLFSWSRNSRSGDSIQPPSSGRHNWVLVDDWSEEKDRVIRDGLGKAAKRGKGKVPDARKSEDTFQIGVQDWRDPDLVDAPSSKDKTEGAAKEQQAGKPGSTAKSGKDVTGPKGGSITPGSGEYNPDLPPVETEGSTSGKETTAHGGIMSKIFGEDDGADFSKEDKPKDPPRPEEPIPDDGDKDDGNEPIGHDGLWVTITPSSSSSPFFDTLLVLVISPLITLSVVYALLILRARIRRRRWRAPKSVVERLPVRTYHTVAASPVPSPRIPSPTSPTPTTPLLQQTPSRPRPRSRTTTGIPESESLLSVNSALQMPRSPLRTEHEKANGSYSSEWKKYMGRQVECVVCLEEYVDGVSRVMSLPCGHEFHAECMTDIFSTPWLTTRRRTCPICKGDVVRSLARGSPSSPRYEPYHDDSDDEVEAEASGSRDRDEDVEQGGILSPAPRGRQTRPDGWLGMLSGSFGASSRASRSSQDDRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP24</accession>
    <name>A0AAD8XP24_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_344551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370964.1">
        <property type="nucleotide sequence ID" value="XM_060502481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP24"/>
    <dbReference type="GeneID" id="85386380"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="72" mass="7672" checksum="43343E424C41BE16" modified="2024-05-29" version="1">MCGWAGVCSLFGRLGAGRIQIGSKRACPCPYGIVPRPRWRRAIWRPGNVTEGQVGFNSQASLSSTYVAGAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPG7</accession>
    <name>A0AAD8XPG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_241963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371243.1">
        <property type="nucleotide sequence ID" value="XM_060501874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPG7"/>
    <dbReference type="GeneID" id="85385773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="223" mass="24395" checksum="E1C1E37186889B1E" modified="2024-05-29" version="1">MCHIVPRSRYPVQASYTIFHTPSMTGSDASIANVPSFRICSLLTCPCRQPAARSLGEIDQRSTAIIICMSRYVKHGMEDGYPHNSRGIRSGPIGLVDFSAFSFASLAPQICPRLPVPPPPKTYNLNFKSRPPRPSPSLKSEPWIMTQNSLSRVMLRYGCSHPRPCKACRSLAYTYSSPSWASPPSSTPRQRRELALPGPSNCTTKSTGSTGSLSSMYVQSPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPV3</accession>
    <name>A0AAD8XPV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_598493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371281.1">
        <property type="nucleotide sequence ID" value="XM_060506954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPV3"/>
    <dbReference type="GeneID" id="85390853"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="489" mass="52461" checksum="7EF5356ED1B58534" modified="2024-05-29" version="1">MVAKRKRVEIVDATPASKAAPSKKTKANTNGSTSKPSKASKAKETATLTGPAEEVTIQIVTGSYDRVLHGITATIKPEGKVDFADTFLFSAHTSAIRCIALSPLSAPIPGQGQKVLLASGSTDERINLYNLSAHPPNRKNQDALSAVSARPILENPKNRELGTLLHHSSSITKLSFPTRSKLLSSSEDSTIAVTRTRDWSVLSTIKAPIAQASGRPSGDTAPFGGAPSGVNDFAIHPSMKLMISVSKGERCMRLWNLVTGKKAGVLNFNRSMLQEVGEGRHSTGEGRRVVWGKTEDEDEFAVGFDRDVIVFGMDSVPKCRVMPDTRTKIHDLSYITIDGESESSLLTVCTEDGRVLFFSTKADDLKKPESEDKTLSSAKLVAQIGGKDDGVVGRIKDTAILQIQEGDSTALLVVAGSSDGKLRVWKIGAKELTAGKGEKAGKLLGTYSTNNRITCVAAFTMIPRPEGVEESEDEVDEDSDESEDDDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ76</accession>
    <name>A0AAD8XQ76_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_158912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371473.1">
        <property type="nucleotide sequence ID" value="XM_060501380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ76"/>
    <dbReference type="GeneID" id="85385279"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="211" mass="23565" checksum="A7DA429BD4538E2E" modified="2024-05-29" version="1">MTINDTDLHLRRLTKRSPANVPYLASLGKPSCIAQERWSTLVTGQKDTIRLQRKSRGSPEEGTRNNEVSNRRQAQATAITNMSTLTSFHRRGCFADGFLPAQSESLVVTAKLRRWELDGPCSIKEEESGAVQSDFHPLLLLPFLLLLDPAPKTHFLSFPSFSLHPITSCTLPSHSLLSRSRKPNRIRATCSPLPSFFSLRTSYPPPTELVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQJ5</accession>
    <name>A0AAD8XQJ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="11">3.2.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_564557</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371662.1">
        <property type="nucleotide sequence ID" value="XM_060503655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQJ5"/>
    <dbReference type="GeneID" id="85387554"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF14">
        <property type="entry name" value="EXOPOLYGALACTURONASE X-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041951378" description="galacturonan 1,4-alpha-galacturonidase" evidence="15">
        <location>
            <begin position="22"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1731607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="46819" checksum="D428F684821B2E2A" modified="2024-05-29" version="1">MVAPTLLGGLLAAALVPFTHAAAGGRPDIKAAPFHPGRAFPASAPRTKTCAVKAGTNGSDDSAAILQAFHSCNNGGTVVLDKTYTICNPLDLTFLNAVDVALTGTVNFCDDIDHWLPRTYKYTFQISSSMWKFGGKDVNIYGNGVGTLNGNGQKWWDRFASNATLERPILFVTDGLHGGSITGLKMVNSPQWFNLIANSTDVLISDINIKVGSTSSNPAKNTDGWDTYRSDGIVIQNSVINNGDDCVSFKPNSTNIVVQNLVCNGSHGISVGSLGQYIGTFDVVENLYVYNTSMSNASDGARIKVWPGMDTPFQPNLSGGGGSGYVKNVTYDTFHNDNNDNAITIDQCYGQKNQTICNQYPSNMTISDIYFKNFDGTASSKNDPRVGSLVCSSPSKCVNINASKINVKAPSGKNPQWLCVNLDTGLLDINCVTKVTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR38</accession>
    <name>A0AAD8XR38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371966.1">
        <property type="nucleotide sequence ID" value="XM_060513249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR38"/>
    <dbReference type="GeneID" id="85397147"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="339" mass="38589" checksum="F79D10D311C7D93E" modified="2024-05-29" version="1">MKGRPIDQLVYEHMFPKPRASDPQNFHALLQRSLILEVRQEVHSFYGHLDTQEAKYPGLDYCNPIHRIRLSRWTWHRRLFRAFDNLHLTPNEIAGLTKWEGTRWAKERYEKEQGIPIRDTAGDGFPDWIEPEDRPAAPVRNPRSRSVDTDDATDHGDEDMDGEESDEELESVGVALNQRLRERAARREAGDMSTVLDEEWEQWLKNVIESGELPYLSNDDISPSRADPAAVAVVPQALFPPRMLSAARAGQWQDIPDFLHDIIRRTLENQNSSSGEETAAPPRLPSISSRNAARERRGTDEHHIGGITNWRRTYSDLRLPVGDSAASPNLQRTAQAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ86</accession>
    <name>A0AAD9CZ86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_72562</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369257.1">
        <property type="nucleotide sequence ID" value="XM_060512738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ86"/>
    <dbReference type="GeneID" id="85396636"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="41915" checksum="B376EE16C0456D32" modified="2024-05-29" version="1">MSALPMAAPPKSPLARYRILSPTASVRVSPLCLGAMNFGDAWKGYMGTCDQKTVEEILDFFHEQGGNFIDTANNYQFEESEEWIGEWMKKRGVRDQMVIATKYTTNFQAGPDAPGIMANFTGNGSKSLHTSVEASLRKLKTDYIDLLYVHWWDYSTSIPELMQSLNNLVITGKVLFLGISDTPAWIVSKANEYARNHGLRQFSVYQGRWSAASRDFEREIIPMTKAEGMSLAPWGALGGGAFKTEEQRKSQEGRKVQASEAQIKISQVLEKIASSKGTIITSVALAYVMQKTPYVFPIVGGRTVDHLKQNIEALALDLSDEEIQEIEGAVPFDMGFPHNFLWGEKVPANPGEVWLLNMGGTFDYVPEPKAIAPKEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0E8</accession>
    <name>A0AAD9D0E8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lysosomal cystine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_716008</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cystine(out) + H(+)(out) = L-cystine(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:66172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:35491"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:66173"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cystinosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369887.1">
        <property type="nucleotide sequence ID" value="XM_060511809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0E8"/>
    <dbReference type="GeneID" id="85395707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000016">
        <property type="entry name" value="Cystinosin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0769">Symport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="30680" checksum="537848930D14EF6D" modified="2024-05-29" version="1">MAFEFLPFLSAVFGWIYFLCWSGSFYPQPLLNFHRKTTAGTTVDFPLINCLGFLAYFVSNAAFYYSPVVRAQYAARNHGLTPTVAFNDITFAAHALLLSCITTSQYVPKLWGFTPAPGTNPSRFISGIASGCIVGVAVVGLIVASAPGDGDPVTSWCALDVVYAVSYVKLVITLIKYTPQVITNYRNKSTKGWSIWQILLDFSGGLLSVAQQAIDSYLQRDWSGITGNPVKFALGNVSMVYDLVFMTQHYVLYRGSDGKADERDSLLRADDEEHQRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Y5</accession>
    <name>A0AAD9D0Y5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_605107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369501.1">
        <property type="nucleotide sequence ID" value="XM_060507315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Y5"/>
    <dbReference type="GeneID" id="85391214"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="12355" checksum="1574910780BECFD2" modified="2024-05-29" version="1">MEDEGFPQGERKWQTFFFGFLNDVKSTVRSLEFGVVGVEGLLLHPDEKGYWARYLLDGSPDEEATPERGRAAPPAWPSHWTTEVREWQVKRTDDRALSLSLSSFLPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D196</accession>
    <name>A0AAD9D196_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_788658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369696.1">
        <property type="nucleotide sequence ID" value="XM_060515683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D196"/>
    <dbReference type="GeneID" id="85399581"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF11">
        <property type="entry name" value="WSC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969203" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="43"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="524" mass="55145" checksum="3332C681429CA69D" modified="2024-05-29" version="1">MKFSAATTLATLLGAASAGSKSDDRTFAVLRFNNKQLVKTRVDPIINPGKPATHVHGVMGGSNFGMSATGETLSQSKCTNAMINGDNSAYWFPSLYFQDPKTKEFEAVDVFYVNVYYFFDGTDDEIKAFPKGLQIFSGNSSARVAPSSGGKQNLEPADGPIQPVQWTCPRSNYNPPSYPANSDGTTAGIVDPNNDGSGVGFPDQNCDGYASPLRADVHMPSCYNPNAALTDYESMAWPTNKGASNSRRKNCPAGWIHVPHMFFEVYWDTPKFASRWTPGQGSQPFVLSNGDATGYSLHADFIAAWDESVLQQIIDNCNAGSSGMDKCPGLLKGLNTNKDCTISSPVNEVVDGLMSALPGDNLLTSFGSIVGGGSSSGSGSGSVVKPSGSSASSAATAASAKPSAVQPSASKPATSGYVSQEEVPKTSAMVSSELPIQVAPEKASTKVAETSAAAAVPTTNAIAPKPSASGCSRKTRTVYKTVTVTSPAEESKAAATPAGSTDNYKARRHVHEHEHLHRHRSNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1G2</accession>
    <name>A0AAD9D1G2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747667</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370084.1">
        <property type="nucleotide sequence ID" value="XM_060513481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1G2"/>
    <dbReference type="GeneID" id="85397379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="57"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="31469" checksum="398DE6B490729843" modified="2024-05-29" version="1">MQTAQRPHARPRRTIPPPIEHRNTASHDPSSLDQFAIPILRFSDDTENDLIGDEIVVIYYHGGGLYVGEADSEELSCRRIAKDLEGAKVYSVGYRLMPSFPASTCVTDSLDAFHHIRSLHPSSATKLIIVGSSSGGQLAAAVSQAVPRGSLHGVLLRCPVTSDGGSSLDYVPSSLWHAYTSPTSPSFVTSLLGVFSRAVPRDGLERMPLEAGTETLAALPRTWVQVCSNDTLYSDGVCYAMALAGAGVEVRVEVVRGWPHTFWLKAPWLARAVEAEEEMVRGLRWVLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D266</accession>
    <name>A0AAD9D266_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_601539</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370609.1">
        <property type="nucleotide sequence ID" value="XM_060507109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D266"/>
    <dbReference type="GeneID" id="85391008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000175">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="306"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="620" mass="66875" checksum="7601DE25791BBDBC" modified="2024-05-29" version="1">MALRPAALALSATSPLLRRAAMQPATMQSIFRLATSSARPTATALTRTPGLGLALQLQQQQHQYRLFGTNNAISRNLLATRESAANRNPGSATAQNAFYQLLLKANMPAIVIERYNSGRFARNDAVDQAYAQAIGMQSTGAVGGMGGHDHLPSAFGNVGTLGGQELNQQSPGNLSQAQLQAVGQALAARSRDSNMATAKVQGNGLPTSPLHVVVDESFGGVIFRWVKFVLWFCLFTYLSLVVVTMLVEGLNLFKRPGGKVDSEAKAENQTTRFADVHGADEAKDELQELVDFLRNPDKFSTLGGKLPKGILMVGPPGTGKTLLARAVAGEAGVPFFYMSGSEFDEVYVGVGAKRVRDLFASAKSKSPAIIFIDELDAIGGRRNTRDAAYHKQTLNQLLTELDGFEQNSGVVIIAATNFPELLDKALTRPGRFDRHVTVPLPDVRGRIEILKYHAKKIKAAPEINFEAIASSTGGLSGAELENIVNQAAVRASRLKNAAVSMTDFEWAKDKVIMGAEKKSMVISQKEKEMTAYHEAGHALVSFYHESGPNKLYKVTILPRGQSLGHTAHLPEMDKYSYTTRDLKSLIETSLGGKLAEELVYGTDKVTTGVSSVSSPREINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2I6</accession>
    <name>A0AAD9D2I6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_736824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371478.1">
        <property type="nucleotide sequence ID" value="XM_060513007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2I6"/>
    <dbReference type="GeneID" id="85396905"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="805" mass="88989" checksum="E6BDC9161A3A6631" modified="2024-05-29" version="1">MVFEDDDEALSGRSGGEEDNQPRPKKRRTNSSAQANGVDTEGPACQSCRKKKARCSRRQPCSACVRYNVECVYDDRRSKPGLRTGAVENLSQRVATLENMFLGQGVLWQQVFNCLNSAASRNATSPSQDGSSNVSLNERTVALKNTLATLAEGGEPALTTLATIPTKDNATLEKTMEKPARPNLNFDLMTEADLLPELDLMDALVDIYFSNIHPWIPMLHVRQFRERMQDPAQRPHLSTIFHAIVSLCARFSQDPRLGLHEEKTRRARRCRQFVILNSMESFSVENLQALTIIAFDTIGSGRGPSAWSIVGSMTRTVEQLQLSVEDEDQPPAAKHLIKRMAFLPLCRSWSEREERRRVFWNIFLMDRFCSVATGWNFSLTSADVKRRLPCEGALWENGEPLQTPTPYFGVADQSSGSSGTLPTARLEEAAQDSLGGFAYCIEATESLSLVTSFFLQQAIDVSKPHEIQVWLMKFKQLDLRLVQWKIFLPEQWREACVLNVDGIMDPNLTLAHLTHNSSVVLLHQGVAYPLPEWQATGIRLPSASSAETCMAAATEVAIIAEKFLQDSQQVVSSQFAFCLFICGRMFLAHSTYYDVALPDGFDSLVNSLNVIAQRWNGLGDVSDNLASKFAGRLIQARHQGRGMLDIRQAVYSDDTRPDTISVSAGDNPKTPGLSRVRSNHRDIAFSPSQATGQEPAFLGGLGTSTMDFEQEASPDSISLAFPPLPIAFHAQSTSRGPTAMPSPVPGGAILPSHPNGYDHFDVGVVNNHGNTHHPVGDFEDLNAYLDYSFLPNQRISMFSGAAEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2P7</accession>
    <name>A0AAD9D2P7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein bS18m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_746802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370985.1">
        <property type="nucleotide sequence ID" value="XM_060513320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2P7"/>
    <dbReference type="GeneID" id="85397218"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.640.10:FF:000013">
        <property type="entry name" value="37S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="23715" checksum="6C2C85FD4EC1B86D" modified="2024-05-29" version="1">MPPRLPLISAIKAPGALMARVARPFSSTPAVAQSSSSDPIKNLLNLDEKPKVHSADRIRGLINNGSKARLEGAAARKRTMLESLREKKVSDDYVKQMPRRWRTGEVYAPHDLSPLEMEKWRRQKTVTVDVVDLLGINPLDHYRNFSMISEYMTNFGQIRHNKETGLKPTNQRKMAKAIRRAIGMGIHPSVHHHPELLKKRFRLNASWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3F1</accession>
    <name>A0AAD9D3F1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_598178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371690.1">
        <property type="nucleotide sequence ID" value="XM_060506938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3F1"/>
    <dbReference type="GeneID" id="85390837"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="117" mass="13455" checksum="5D545A4ADC86D514" modified="2024-05-29" version="1">MFLFSSRNANLLLVLLQYRVGRLPTPARLAWKLAEAWSLMGWDGALEQFSSKSGKLEPQRLCSTEGWRLAMLTHAVSQMLIIPETTCDSLQALRRRCRCRRATADDDMAFYHISYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6I1</accession>
    <name>A0AAD8U6I1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358381.1">
        <property type="nucleotide sequence ID" value="XM_060509584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6I1"/>
    <dbReference type="GeneID" id="85393483"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="82" mass="8922" checksum="FE7F8DFC77C0FDFD" modified="2024-05-29" version="1" fragment="single">MELQAVWRLPMVDLIATAAVSGLVACAWMCSGWFALWYRHPGRCCQMAVQIDALTIKVPSILTGTACSTAANPALAFFFPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8L6</accession>
    <name>A0AAD8U8L6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Family 2 glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_592458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358382.1">
        <property type="nucleotide sequence ID" value="XM_060506537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8L6"/>
    <dbReference type="GeneID" id="85390436"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06421">
        <property type="entry name" value="CESA_CelA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF2">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="504"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="9">
        <location>
            <begin position="256"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1708700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="660" mass="74472" checksum="CEF7D01967CAEF6F" modified="2024-05-29" version="1">MSRPLTPRGASPDSSLTPPTNPFGSNPFDTDNDSSAAPSLASDSTFTVNAVGQTHPYDTTDRSGQRSSWADSSHHRLSRPGIPSPLAREVPVYNEKVHHQSSSETDVEASHVPPVISDPEKAKETHTTALPPSSGESFPKRLYGRFRATYCPKEEPPLVLPVCPNDTEKLSYVHTNRLLLYIFGIFSFLSLGAGMWLFALSAPAFYWYGVFAGAMCIYLLISYAVGIIGRDWDYKAHLDLVERFPITEENAPTVDIYLPCCSEPIEILENTYKHIVNIDWPASKLQIHVMDDGNSEPVRLLAEKYGFNYSVRDDRPRLRKAGNLRWTFAQTSGDFFAIFDADFCPRPDFVKELMVEHLGDDKTALVQSPQYFRVTDDQTWVEQGAGATQELFYRVVQVNRNRWGASICVGSNALYRRESLVEVGGTAEIGFSEDVHTGFGAVDRGWKVKYIPLCLATGVCPNSPRAFFSQQMRWARGSTTLLTNGHFWVSNLTLMQKICYLSGFLYYAAVSLNIFLAPIAGTLLLAIRPEWFKFWNLAFAIPSILYGVILMRCWAKAKYGFNVQHAMTVQSYAYLTAIKDRLFNIELLWAASGDSKAHKSNKYRNMRLLCIIWTLIVTGAMVGVVTWRLVTGFTWYHPLPLIIINVYNLFINHYFMFCNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8S8</accession>
    <name>A0AAD8U8S8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_592219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000187">
        <property type="protein sequence ID" value="KAK1709133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358472.1">
        <property type="nucleotide sequence ID" value="XM_060506513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8S8"/>
    <dbReference type="GeneID" id="85390412"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF76">
        <property type="entry name" value="CHAIN OXIDOREDUCTASE_DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="28268" checksum="10AB9217C74F44FF" modified="2024-05-29" version="1">MKGKTTVVSGSLAGIGTAIAEKLSMGRANIVLNCPFPQLLAECEQVGAKMQTPWISVCADMSTVWGPAALVPAAVARFKQIDILVSNAGMIQLGPLGEANADTWDQALNLNSRGAFLLVKAALPFHSSKRGGFRIIIVSSFASRMPEVNQSIYAASKGTLDAMIRVWARELPPVYRCTVKAVAPGSISTETFFKIISSRFNIVKQEMDLRTSIKGAFGDVENVALTVAFLAEERSQSINGEYLLLTGSCYINWLLHQLIVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U971</accession>
    <name>A0AAD8U971_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_235182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000288">
        <property type="protein sequence ID" value="KAK1703228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357245.1">
        <property type="nucleotide sequence ID" value="XM_060501837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U971"/>
    <dbReference type="GeneID" id="85385736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="26592" checksum="2E8F4314034D701D" modified="2024-05-29" version="1">MQPITPQQPGKALPACRTEARDDGAGAKVERSGAVRAPFRPSSSPYVGSAQPLTQTERAAADRARPWPGIIASIRAFFRRPDEDQVNSNSTNGHGDITTVTPCAQRTVARCDLDARSARDNAAADVDSTVDDATAGATSPRSGATSTSGWLMENRGLRDTSTLARGDMPVIEAPGDQVNDSRSPPTETAGSRHVVDAGSEDVSIDAHGLLIFDKIVGHRRDPQTQTIFHMRVRWRNGALTWEPEASIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Y8</accession>
    <name>A0AAD8U9Y8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sterol uptake control protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_588145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360237.1">
        <property type="nucleotide sequence ID" value="XM_060506104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Y8"/>
    <dbReference type="GeneID" id="85390003"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="45509" checksum="B7471AD54C479BF6" modified="2024-05-29" version="1">MSWEPTSNSNAAGLSRVPSFQRRSSSRKGSSGSRKTQTPSISPIDHSLTPPSLLEATLNLPADFVSDRGSSIGNRRSSIAASSPDPFPYFVKFSTEPVEPVHLSKWITDLELMHHYSTATSLTMPRSSDVSSIWQFEVPKLGLTYMFLMHEILAIGALHLGYLHPEQRESYALHASQHQSDAIAGMRESLMNITTENCHALFAASSLLLLNAYSTFPYQRGAPHSQEAPTVDDVLDVFLLVRGMSHILSSFQPSIQTGPFRNFFTEVVTPASTPLLEAVTQHLENLQISLKTSSADEPTKAIVSKEIDVFLGWIMHAVETTAFPELRVALTWPINLTEEYLQLLRNRDPAALTLLAYYSVVVRSTEATTWFMQGWGINSARAIVSDLDPEWKEMVKWPLAFISDRSIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAC5</accession>
    <name>A0AAD8UAC5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1479-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_770014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357918.1">
        <property type="nucleotide sequence ID" value="XM_060515334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAC5"/>
    <dbReference type="GeneID" id="85399232"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010856">
        <property type="entry name" value="Gig2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613:SF1">
        <property type="entry name" value="DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30613">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBIU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07350">
        <property type="entry name" value="Gig2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="45172" checksum="E43A71568F62BA24" modified="2024-05-29" version="1">MPGGVRKWPAWPEYTDKDALEPKDPDFLDTKKTIISQYGAEALTESWLRVCEQLKAVTDEIVDKGRGIIPVFNARMLLDKGFTEAEMDEAKRVGTFVIREVVPKTETTQHYADLKHCVAENKQKIQGWPKETPSMLMLYDSPTQNAVRSHPNHLQLQRLLNQLWHDESGEDTSPDPLVYYDGVRDRPPRQKFLGLGPHIDAGSLARWADAAYREVYGNIFSGKPELHDPYDLSLRKIADQELYPGVAHSSVFRSFQGWTALTRTAPSEGTLLVYPNVATVITYMVLRPFFKPPVDSVDVMDATKWTLDESGLFPGTSQWLSRSSHPHLRLEECLIHVPKMEPGDTVWWHADVCHAVDPVHEGSENALVLYIAACPTTINNKAYVRRQLSETLYGRPPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAX9</accession>
    <name>A0AAD8UAX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000260">
        <property type="protein sequence ID" value="KAK1704655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357456.1">
        <property type="nucleotide sequence ID" value="XM_060511020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAX9"/>
    <dbReference type="GeneID" id="85394919"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117602" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="12143" checksum="875112C9A8587CAF" modified="2024-05-29" version="1">MKFTTILLAVLPLIAAGGGPKDPDSLPRIPLPLHELPECWQECLQLENIHYPPNINKVNVHDFCVDDGYHLRWWSFHTLATCTAGKCNREEGIQSQKWLFDLCKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAY2</accession>
    <name>A0AAD8UAY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_174459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000204">
        <property type="protein sequence ID" value="KAK1707766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358144.1">
        <property type="nucleotide sequence ID" value="XM_060501481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAY2"/>
    <dbReference type="GeneID" id="85385380"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="62708" checksum="3A0B76C38C220E31" modified="2024-05-29" version="1">MADDPFAINKVSTESDTFFEILRYRKNQQTRQVHRLEDLLSSNQKRGVRQIADHPQLRSAFEKLAGITGIRSGMSTGSLHKFMSVRCDEEIVNYLGLIYDIWLHIVGGVESNLVKIDTDTVQFLELKCPGFSARDERDLHSIVASGRAFRNFDQTERKFFWQNLCSLNVVVLSVSTFFKHFRYLEECASCMKSLVSLPRYGSLHDAFRASFKRPTIEDNRYPVQTSDSTLEVRVIEPELQFDAGWCQMWLFAMRHFQNMTTNPSVLPQFAILASRLYFETDKIMVLKSLCPEQNTVLHAESYPDMQRRTSWPVQDADPRSKRSTLQPFVTSDKGPKLNVRPWSTREAYERNKEFLFLDIMNQQPVLKGKSITSVFLLRTIYVAFFRKLSFTSDADSMLSAVSHHRSYDEVEAIATTLLDSHEDNMDDRQQDSRESRTQTTAAESTDAVADHEENQRRVTFKIMKEGILQKEEHLVFDTTVQGNKARVESFVRGLMLSHSRTIPFSPKKYPLLVDECYNEIIQKGSDCIFLVDSSHVDMRNIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBM8</accession>
    <name>A0AAD8UBM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359803.1">
        <property type="nucleotide sequence ID" value="XM_060506207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBM8"/>
    <dbReference type="GeneID" id="85390106"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="35873" checksum="E5B1FD4D4818B521" modified="2024-05-29" version="1">MAYQNSMRSLQECNDELQDQLRKLKANFDSYKVKKLRNQAIANSSKVPDDAIKSSWKQMAYNIRNIAATTPTASLTEKDILQHGHHYTDKSCAICEMPCEHLELLRDDELRASVIEGYIWRAVFRRIFEAGESYDGGKSWAGKPGMLFTALFRSLLGDAVKCADEIEFFQWKASSADMIDRLMGVDEDEMQQAIDEEYRGLLRFLPRDCVDRKAQRKQLHREIEKVFKGAVELHRVFMKSKANFYIDWAGVSSSSEDVTRYQPDMHDAEAWEKDLDATSIIRFVISPSLVKVGNADGGSYDKLNRLAKATVICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBX5</accession>
    <name>A0AAD8UBX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_632669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361332.1">
        <property type="nucleotide sequence ID" value="XM_060508985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBX5"/>
    <dbReference type="GeneID" id="85392884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001558">
        <property type="entry name" value="Ribosome biogenesis GTPase Lsg1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="141"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="540"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="589" mass="65924" checksum="6F9EDF8B91C91A19" modified="2024-05-29" version="1" fragment="single">MFSREILTICQYLTNERQEASWVKMRSVTEQGALDEFLATAELAGTDFTAEKMNNVKIIHTDQKNPYLLSGAEERAIIGKQKAHRGRLTVPRRPKWDASTTPEELDRRERESFLDWRRGLAELQENNDLLMTPFERNLEVWRQLWRVIERSDLIVQIVDARNPLLFRSEDLEHYVKDIDSKKENLLLINKADMLTLTQRKMWAKYLKENGIAYRFFSAHLAKELLEAMESDNESEEEEPEAGSSSKAATKDAASTEEESSEEDEEEEEKDDKEEGGAETAQPEVSQPEAEADVDDEDTRILTVEELEDIFLSHAPENAEPGHKLQIGLVGYPNVGKSSTINALIGAKKVSVSSTPGKTKHFQTIHLSDNVVLCDCPGLVYPNFANTKADLVCNGVLPIDQLREFQGPAGLVTRRIPKSFLEAVYGIKIKTRAIEEGGTGTPTAPELLRAYARARGFQTQGLGQPDESRASRYILKDYVAGKLLYCEPPPGTVEGPEFNAELYDETHLPEKRRRALSTSMDTMSIVDDDISIAPSDLAALPAGPKSKQIDKGFFGPNSSGGHTKMPFSHKYTEQGQKHLSGRKARAMIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC87</accession>
    <name>A0AAD8UC87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358911.1">
        <property type="nucleotide sequence ID" value="XM_060510927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC87"/>
    <dbReference type="GeneID" id="85394826"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="24859" checksum="DE2D3BE18D99853C" modified="2024-05-29" version="1">MSSTGSSSEAATAPKSALTDRELEILKNAWSSLKSAPEVDYAKLAAACGMTNPRSASNAWSGIKKKLFSDLPAQSSDTAGSSPAKRKIATPSKRKAAAAAAATTSSDDADELAAAAGANLNSDGEEKLVVETPAKKKRATPAKKKAAATPKAAAKTTESDENADEAAEPETPVKKKAPAAKRKTPAKTKKAAAAAAAAPPPEKAASENEEAADGEDAPAADVAKLEVKDEAANGDVEMSGGADTGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCV8</accession>
    <name>A0AAD8UCV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADPH-dependent methylglyoxal reductase-like protein GRE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_638355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359490.1">
        <property type="nucleotide sequence ID" value="XM_060509362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCV8"/>
    <dbReference type="GeneID" id="85393261"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000191">
        <property type="entry name" value="Methylglyoxal reductase (NADPH-dependent)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="37283" checksum="879AEC66EBB80017" modified="2024-05-29" version="1">MARVLLTGGSGFIAMHIIKVLLEQGHSVITTVRSQAKADIISQSFSGYSPDKLGFVFVPDVGQLGAFDEAVRSDPPFDAVIHTASPVTYEVKNIQADLISPAVDGTTNILQAIKAGAPTVKRVVITGSFVSMLDMSKGLWPGHTYDETDWNPITAEEALENPASGYAASKTFAEKAAWNFQSEESPGFTLSVILPPLVFGPVLQRLNNLDSLNESNQFIRSFFNGSMDTAIPTAEYPVFADVRDIALAHVRAMEEPEAGNKRFFVANGHYSNRDIIGIIRERSAKYRHSLPSEHLPGGELPEDVFAINTQRSVNILGMEYRTLEDCIADTVESFGAVESRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCX0</accession>
    <name>A0AAD8UCX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_754858</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361857.1">
        <property type="nucleotide sequence ID" value="XM_060514541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCX0"/>
    <dbReference type="GeneID" id="85398439"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000001">
        <property type="entry name" value="Uracil permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF1">
        <property type="entry name" value="URIDINE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1720346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="59952" checksum="D6DC268BBD3533C5" modified="2024-05-29" version="1">MGLLNRLRVPAAAGTSDIHGRDALLNNDDLRPLKLADRTWTQWTYFTFWFSATATVSNWYASSTAQALGLSMWESLACAFGGQCLIAAVITLNGRPGSCYHVGYPVVCRAAFGIYGAWWPTFNRAVMAIVWNGVNAVQGGQCIYVMLHAIIPGIANIPNTMGEGSALTTAGMIGFVIFWLITCAFLVIPVPKMRGLVYAKLCVFVVSAVAMLAWTATKAGGLGPVVRQGGTATGSKRAWLIIQFLMLGAANCATFASNAADFQRYAKKKNDVVVGNLFCFPVANFIVAAVGNLVCASSELIFGELIWNPVTLLDNLQTAEYTAANRAGCFFIAGCFAYCCIFSSIFENSLPAGNDIAALFPKYLTVRRGFFVCAVISFAINPWFLLGSASVFVSFLSSYQIFLSAITGVLLVNYYIIGRGRISIPDCFTSMKSGAYHYSYGWNIRAYAAYIVGIIPNFYGFLNNMGVSAPIGVTRFYFFAYWVGLFLSGFTFWVSCKIWPPPIMEEGWVEPKDYVRPEELEGDGQVIEAVEMPQSGEVVYHEKGLGRKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDY4</accession>
    <name>A0AAD8UDY4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_633002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361168.1">
        <property type="nucleotide sequence ID" value="XM_060509007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDY4"/>
    <dbReference type="GeneID" id="85392906"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="22885" checksum="074A9E2CEE98FC63" modified="2024-05-29" version="1">MGFLESRWSPVNVVFESHKSPGKGGKFLLSYDSERHCESQVRFLTGHKGVTAKAAEKLMGGRTVWQITVDGLLVQEIQSPTSTDGVTEQHLTVPNSDAALRAKQCLGLPDTRVERSEDSARWLVIVKSTFTEVELDRLAFSDVERAQVSVVMGPRKPRPVPKPDSRIEEESNRALPEASVPGPIVSVEESGKPKKTGAARAFLKRFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDZ7</accession>
    <name>A0AAD8UDZ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase II subunit RPB9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA-directed RNA polymerase II subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_721620</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362206.1">
        <property type="nucleotide sequence ID" value="XM_060512397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDZ7"/>
    <dbReference type="GeneID" id="85396295"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1721410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="24836" checksum="91FE3DD26DAF5E4E" modified="2024-05-29" version="1">MATPMSTNSQDDGANKKLEQITFRFCSECSNMLYPKEDEETHRLQFTCRTCQFTEEAQSTCVFRNVMNNAAGETAGVTQDVGSDPTVGDPQSVLAPVVCIGCGHAILCSGCGNPSDDFNVSAAPTHQHDGPQSKKTEITWDDLMDMAEDEALDEYDEEKESVTSDEINHGFAGIALNNEPDSANRNVSWPTFQLAGGEAVFFQSQQRSAETGMKLFYVCCDCGHIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDZ8</accession>
    <name>A0AAD8UDZ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein NO VEIN C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_765934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000164">
        <property type="protein sequence ID" value="KAK1710925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358985.1">
        <property type="nucleotide sequence ID" value="XM_060515260.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399158"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052957">
        <property type="entry name" value="Auxin_embryo_med"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387:SF0">
        <property type="entry name" value="PROTEIN NO VEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32387">
        <property type="entry name" value="WU:FJ29H11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1500"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1704" mass="192718" checksum="C329A574CCB02C51" modified="2024-05-29" version="1">MRTLTYDMAAAPGRTAHQPTARELVEGIAEEHGIISESDLTEIGAMNQRIRSVVEKALLQKDELIGSSILTLAKNLNTSHARFVFELLQNADDNKFVAAKCRGVEPYVKFSVYRDRIEIKCNEDGFTHHDLKAICAIGQSSKNRSHGYIGEKGIGFKSVFVAAYKVNILSKDFSFSFTHRKGDSGLGMVTPIWEPDFIPQNELAPSSITLHLHQYDDASLSEAKRQREEINREFENLPITVLLFLRNLRRIEIQFHDDDDKKTKRVEYSFSTSSPSTLIDIVWLFDQESSSGETFQRKHHVARQVIRDVPPNENREFSEGHGRADAETEIILVFPLADDHTPIVENQPVFAFLPMMPLGFKFIIQADFVTNSSREGIVISSARNLAIRDGIATCFIKAVDEMCQHPTLQFQWMRWLPQRHSYPWDNFWNGLLEDIKNRIKTSKTLRTRRSGRLGDIHSLRRLQSNWLDEIGSPLFDDLDTEMYVAEEYQVKDLSLLEPYGLKWLSADDRLARIEHDLGQPIDTSRMKNSSTSPQWHSQAAGMIQRLVATASPQSLARIRTLDIIPLRDGSWTSINRNRRPIYFPYSGNGLEIPTNLPLSLLFELLGVQTATVEEIQQLIFEAPIPNLKTDATLLASVSNLKFLYSSHHDTSHCGESSTAIANLFVFDHTMEVQLPHRQDVYLATNGPYEPRSLLQPRANHPDGCFVSFLHNQYFECPPETPAGLEQTWSEWLERVLRVRRRLRLTSSTSPESLSPELDYVRIFRPECFIEALQYHWILLNHDDSSTPKFLCNLRALNITCKDGRDYPLAETTLPLLELQAIVSSYLGDLTISFLQIDEAAHSASFHSKWGFLVNKLGVRSRDDVNLYLSILEKITEGQPQQESYSKILCLYEMIQLRLEESASKDQVAIIVKSTAAEDGTLTWRRPDTCVWAAPGVPYAYTALEGQIMSGCSEDLAHSLERFMKVTLGIGDWDGSCCIRELEHMRSVGCNDFDWVVEIYDFLHNCDMSQTRFQRNVPDALNSRALFSTTPLIFVPGGETSGWCTTAQCLWSSGARIQGRTTLSSIYEDMEEFFVETLGVQRLTLAMACDELLKKGNKQPIATIAEIKETIWAVNTLVQSATSYPDPEQLLESAVFPVQYPNGQVRLETSRTQFVIRDRKPLSEMFTSKVKFLDFSLDEIHKLSNLLSWLRLDSRYLSSSVKEISTVTSDLQVRVQRPDRDIKRRASGICRVASHFDSPRVDDVVGLYHTLRAAEVFETHGISSEVHLVQDGKAHIHVKPSSELHIRETAGRLQIYVPLNKERQDFCYHSSLPRRLLEWVMTEPETQLCGAIPHRAISAMSSALNAPIQSVSHILEAEGIIDLGGRTEVEQGQEFPRIPDVSPPPAEDPQQDGFAVEMPIRPFSLTGPRSVSGFAATHPMFTQQSSTPASPDNNRSYRLQPNSPVGVAAITPPSHIFHFGQTSTAPAATTSPRYDAFSTEYLRILNNVIFAARRRSFPEFGSTRTGQSAECASTPTSNPWIPPGSDKKIGAAGELFVYELLSHLSPSLPEFGMDAWQSTMRKHVAVHPEYSYVTHWEGQETADIVYNDKFGVLTKILIERGYLEPTKWVDKKPQYFIEVKTTPGDAARPFFVSKYQYNRMRSYTDASTSPGGSYTVYMLLRVFNLTTLDIDFNVYVDPYALQQKGTLVFTEHTWQVVPVQGNRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE99</accession>
    <name>A0AAD8UE99_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_58263</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360210.1">
        <property type="nucleotide sequence ID" value="XM_060505568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE99"/>
    <dbReference type="GeneID" id="85389467"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069799" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15779" checksum="472FC712735BC6E2" modified="2024-05-29" version="1">MCGRLLFFTLLTQSALRIPSLPLRIPCFSPRSGLHYEDGKQIQKLHNPPCRIDHRQKGSLQGPRQPWTIIDGSAQPFPRFSASHFHPYPVAGRSGRRTNPPAISSYPLPRHLQGPWNGVRRKITQVNQLSNERPNETAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UES4</accession>
    <name>A0AAD8UES4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_588170</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360243.1">
        <property type="nucleotide sequence ID" value="XM_060506109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UES4"/>
    <dbReference type="GeneID" id="85390008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042099815" description="Mannan endo-1,6-alpha-mannosidase" evidence="12">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1715444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="50976" checksum="439CA4B7F50B906D" modified="2024-05-29" version="1">MPSPLVSTLSGALLLLGHLLNVVAELDISSSDSIKESSRSLAKDLMTFYKGDEPGQTPGILPWSSEDINRYWWYLSGSFFATYLDYWHLTGDDSYAATVSKALQFQVGPDDDYMPPNQTASLGNEDQCFWGTAALMAAEYGFPEVDGKAKWIDLAKNVWTTQASPDRYDETCDGGLRWQIPLSNKGYEWKHTASNACFFNLGARLARFTGNTTYSEYSDKRWDWLTGVGFVDTSNWKVYDGALAENNCTKIGKAQWSYTPAMIIQGAAFMYNNTNGSEIWRDRAVGLSDTLLKDFFPDGVIFESACESAEGHCPTDALFYKGFVHRWLSSATQLAPFLANTWLPVLKTSAEAAVKQCKSGNSGVSNRCGFYWTSGKFVDPMTADNTTGIGEGLSVLAAVSNLLIKDAMAPIVEAAGSGGSSGSSSSGTSGGSPPISTTSTTATPGSGARQLGMDLKMSFSLGLTMLLAWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEZ2</accession>
    <name>A0AAD8UEZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_454966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361742.1">
        <property type="nucleotide sequence ID" value="XM_060503175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEZ2"/>
    <dbReference type="GeneID" id="85387074"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="211" mass="23635" checksum="161045FD30C5DA24" modified="2024-05-29" version="1">MRDIRTETLNFIPPQMNADEHNCLCIAALSRAFNNFGLQAWQSATVKKPAGDALETAVNGLTRLGSTRQAPWRDLSHKFRTATVPPTNLTLERMLYIDRRRLSLSLFHRQPHRIELSNTYLAPLQGECRPLPARHSAPSPLYTRRPYTNRDGATAQHLPVQQLGTRSRGLVLATAITPDSATGDAMNTLYPSARWLWGSSLARLPPLVFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEZ8</accession>
    <name>A0AAD8UEZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360321.1">
        <property type="nucleotide sequence ID" value="XM_060514718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEZ8"/>
    <dbReference type="GeneID" id="85398616"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024526">
        <property type="entry name" value="DUF3807"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40642:SF1">
        <property type="entry name" value="YALI0F31295P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12720">
        <property type="entry name" value="DUF3807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="164" mass="18252" checksum="50246B485BA02BC7" modified="2024-05-29" version="1">MIPSFAAPSVSNNDLVAFFEAHFSGAAVRNFQADFLNPNHQPDAATANASVEEDGDVFEEEDDLGYYHDGVKRTLTDDQIAMFRHSELETIKREQERRSTAVRQAGETGEDGTLRAAEPSRPPGKTAKNKKKKRGKGKGQEPKPDLRKRTWDVVESGLDTLDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF71</accession>
    <name>A0AAD8UF71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_584424</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361903.1">
        <property type="nucleotide sequence ID" value="XM_060505758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF71"/>
    <dbReference type="GeneID" id="85389657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF42">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="23"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="532" mass="58213" checksum="E1B7D30225CBEADC" modified="2024-05-29" version="1">MGFASAKGTNDPPEVRNWRIHFIALVASMAALSMGYDTAVIGGTMALDSFVRDFGIDKMTTQEKNNSLANIASMFQVGAFFGALLTFPVAEKYGRKKAIMMAALIFCVGGAMMSGAKGDLKLVIAGRAIGGLGIGMATMTVPVYIAETSPPSIRGRLVGIFEIFSQGGGMLGFWINYGTSRTIDVENEAQWIVPLALQLLPAILLFVGIMVCPESPRWLARGDNFEAAEKVLVYVRRLPADHPYIQNEMSEIRQQVEERSTVRLSKKQQLQKLLAPGTRNRVGTGTFLMFLQSYTGVNIMTYYSVSVFETLGITGTSNKLFSTGIYGIAKMLGMILFAVWVIEGLGRRSGLLWGAFIGSIPLWYVGGYVMVANPTAKAASGVIQQDAWGYLAMVCIYLNAFIICSTIQGITWTYASEIFPLDIRMLCVAMSTACTWLGSFVVARATPFMITDLGYGTFFMFGGFLIFIGVWSFFFVPETKGRSLEDMDILFSRPTHVVVWAQLRGRPILSTNTPMSPRGSMDKGEVKVVDMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF89</accession>
    <name>A0AAD8UF89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cutinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_656372</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359660.1">
        <property type="nucleotide sequence ID" value="XM_060510871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF89"/>
    <dbReference type="GeneID" id="85394770"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042278602" evidence="3">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="23978" checksum="DC1C476ECD3A9A1E" modified="2024-05-29" version="1">MFLTKLFTFSVLSLPVVNGQGTDDCPEIPETGVTIGDPVPIRPEDIPAGCSDFEILVARGTSEPNYVGGGGKFGIIVGDPVVSNATVALPGARGYPYPASSQIITGVRQGSRDVVNRLKSQAAACPNQNFSLVGYSQGASVMHAAAADIPAELYGRIKSLVMFGDGYLKLGASLSKFPAGLNEKVRQVCAAGDPICDAGGTCTFFHLTYIRPEFIDPAVDFIVQKFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFM3</accession>
    <name>A0AAD8UFM3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein ZIP4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360454.1">
        <property type="nucleotide sequence ID" value="XM_060514705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFM3"/>
    <dbReference type="GeneID" id="85398603"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090173">
        <property type="term" value="P:regulation of synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039057">
        <property type="entry name" value="Spo22/ZIP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013940">
        <property type="entry name" value="Spo22/ZIP4/TEX11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40375:SF2">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08631">
        <property type="entry name" value="SPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00031845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="930" mass="103916" checksum="B7A3D6E850B8B598" modified="2024-05-29" version="1">MPPKRHAKSPKSNNTVDKINSIATFSKTLSTRLPSANDALSIDALLAELNPQLETIIRFSGSPRAKSQRVELDKRGTELWNQCTRQRRDNADGTATAAAAPTARKKLLLRSRTYAFFMISIARGVSGGAEPQLADVAHVMKLALKAGKTCLDDGGTSSSALKLAETVFEKGAEYSAALELHWQAWKTDNFPVMEFMYRKGHLQPSALDPSSAEKMAEVLFEIGKGLSKKEDFGMAVRWLERGYDIINAQDLSILSRDAIELRLSVCQALIHALLGLGTPESSQKALDLISYIESEIGEKPVVLLLRLELLQKAPAEVFDIEAYADILRRMVRTFNFSEAHFKLLVHHARKLHDKSPTLATSVVDGMLRGTIVSSGREEWVERLVLLRIWMETTQRDGMRAIEELMGVLAGLQDNLSKPFGASTAVGALTLIWKKIEVNYNQGHFDFADGWCQVALQPLFQNGGPANMSRLGRKLILCALGRNDTERARQVFHSMSEAAQNEPMTRYLMYKAALRLSDQELAAQCLERVALSAPGDPNFLYACVLEAQQAGDKVCAMQAMKQLVEKFDFSEASPIHLPALLRCNIRLAVSVVESEKGARERHSAVEEVIVLLEVAVKAIQRDPRNKDGNRLFTVKELDWFCQNAYNLGLKHSESWDVKHLIRLYNSCLAIAKHYPEDLPAEAASDLVFRTMFCDFIAAAALVSLARTEDNVEEQLQHYLVMRRHVMAYNAAMEKQISDCLDTRLKIDLTAKLATLMVFDFEAAMALKKTDELGFIIRTAVTCRDVNTLKAMGDIALRGKLPGQALYSTLGVIVNEIWELEKMKGDRLAKYIRCMFHAVLPLDAALGQRLMKQAVDVARDSRKSQHPFPAEELEWLVTMGFNQAVDAYNARQDDECNTWADLALNLAHYGDDGGDLEKRVQENRMKLKFDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFP2</accession>
    <name>A0AAD8UFP2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoadenylyl-sulfate reductase (thioredoxin)</fullName>
            <ecNumber evidence="3">1.8.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">3'-phosphoadenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">PAPS reductase, thioredoxin dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">PAdoPS reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_756671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[thioredoxin]-disulfide + sulfite + adenosine 3',5'-bisphosphate + 2 H(+) = [thioredoxin]-dithiol + 3'-phosphoadenylyl sulfate</text>
            <dbReference type="Rhea" id="RHEA:11724"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="EC" id="1.8.4.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.8" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359870.1">
        <property type="nucleotide sequence ID" value="XM_060514781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFP2"/>
    <dbReference type="GeneID" id="85398679"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23945">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000151">
        <property type="entry name" value="Phosphoadenosine phosphosulfate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011800">
        <property type="entry name" value="PAPS_reductase_CysH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00434">
        <property type="entry name" value="cysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02057">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002537">
        <property type="entry name" value="PRK02090.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46509:SF1">
        <property type="entry name" value="PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="14">
        <location>
            <begin position="89"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00082553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1713817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="38740" checksum="B64C3C17D54C1701" modified="2024-05-29" version="1">MAAVVEPTTQTSSVESSPRLNAADAAKLDRVEVESGYGSATDTSSTSSSIPALPLISLTQPHLKHLNDQLENMHPLDILRFSKIMFPNLFQSTAFGLTGLVTLDMLSKIQKENPSAANVDLIFLDTLYHFKETHTLVDRIQERYPNVALHIFKPYGVSSTEEFEAMYGPKLWETEAEMYDWIAKVEPLQRAYQELGVAAILTGRRRSQGGARDKMPVIEVDDERGVIKINPMASWSFKQVQEYIKTHNVPYNDLLDQGYKSVGDWHSTVPVKEGEDERAGRWKGQQKTECGIHNKKSRYAQYLEEMERKAVEAKGAAPASSAEAAKQGEAAIAPIVKAEKEEQAIASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFX4</accession>
    <name>A0AAD8UFX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA dehydrogenase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_731854</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363552.1">
        <property type="nucleotide sequence ID" value="XM_060512879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFX4"/>
    <dbReference type="GeneID" id="85396777"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046359">
        <property type="term" value="P:butyrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="6">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="5">
        <location>
            <begin position="294"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="45135" checksum="CFDE06B798D57BAB" modified="2024-05-29" version="1">MVQFNLTEDQKALRAKGAEVAKEVLTHAYADYSKHSDQLTRFRATRPYYSKLIKEGLLKAFIPKAAGGDADTLLETAFLLEELYAVESSIVIHLVGSALGLLPLVLGGTAEQQERFLKPFLSGEGDPLASLAHSEPGGTANHLEQGGKGLGVTAKKEGDFYIVNGEKLWTTNSAGWDGKGAELTCLCARYSEDGSSEKSGVNPADNLMVLMVTREVVAQNTLEAFELLSEPELFGHIAVTGPHTRYINFKVPADHVLFAPGKAGPYIEQAFGISGALVGAMAVGTRIRKNDHRGGPMPIIQRQSPADLLISAKIKIDTSRMLVWKALDSLDNGPGEAKSRFESCLAAKIYSSDSAVTCVWDCMQVVGMTSYAQSAGFSRLLADAAVFPLFDGGNVGIRRRQFQKLMCEEEYKPWANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFZ9</accession>
    <name>A0AAD8UFZ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Serine/threonine-protein kinase SSN3</fullName>
            <ecNumber evidence="5">2.7.11.22</ecNumber>
            <ecNumber evidence="4">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Cyclin-dependent kinase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Serine/threonine-protein kinase ssn3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">BDZ83DRAFT_722626</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="5"/>
    <dbReference type="EC" id="2.7.11.23" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360831.1">
        <property type="nucleotide sequence ID" value="XM_060512488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFZ9"/>
    <dbReference type="GeneID" id="85396386"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000426">
        <property type="entry name" value="Serine/threonine-protein kinase ssn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0010">Activator</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 26" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="25">
        <location>
            <begin position="33"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="292"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="409"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="24">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00039418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00040708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAK1717344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="49562" checksum="E77F027A150DA7E0" modified="2024-05-29" version="1">MWRGIGYGGLHNPADRGLGHINYQPKVRVIERYKVVGFISSGTYGRVYKALGRQGQTGEFAIKKFKPDKEGEQISYTGISQSAIREMSLCSELKHANVIKLIEIILEDKCIFMVFEYAEHDLLQIIHHHTQNPRHPIPPQTVKSIMFQLLNGCQYLHANWVLHRDLKPANIMVTSAGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPSKERWPLLSAMPEYPQLATLQPPMTPHHHGHHGHHRGHGYGHHPPAPSGSNLEKCTISQGASSSATSAPQGGNGGGAPLASLGAEGYKLLASLLEYDPVERLTAAKALQHPFFSTGDRLNAHCFEGLKNEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLARPTKKLREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG77</accession>
    <name>A0AAD8UG77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_628879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362578.1">
        <property type="nucleotide sequence ID" value="XM_060508729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG77"/>
    <dbReference type="GeneID" id="85392628"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08589">
        <property type="entry name" value="PI-PLCc_SaPLC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032075">
        <property type="entry name" value="PI-PLC-C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16670">
        <property type="entry name" value="PI-PLC-C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042286410" evidence="1">
        <location>
            <begin position="21"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="43265" checksum="D1D2A1F87BC6486D" modified="2024-05-29" version="1">MSPISSLALKAALLLPLVSAASCSNETYTHNGLTWSRGIRMNQVQVVGTHNSYHREAPLEEHPTQAMMLPNVQNYYYSHPSLDIQLNYQSIRNLELDIFADPEGGHYATPLIRKLANLSTTPDPDLLAPGIKVLHVADADYHPTCKTFIGCLNIVKKWSQAHPDHVPIPFMIEFKTSEAAFAAIGGASPIPWNDTTLLKGLDDEIRSVFAPEDLVTPDDIRRSNLTLEQSVLQYGWPDLESARGRVLFLMDNGPVNPIRDSYTEGRPNLEGRVLFTNSAPGNSDCAFQKLNDPTGTEQANIQAQVKAGYWVRTRADIPLDTLLSNDTTGMREDAFSSGAQIVSTDFQAYGMSSRWNVDYAVRFEGGAAVRCNPINGPADCASEALEPISYVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGL6</accession>
    <name>A0AAD8UGL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_721123</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362818.1">
        <property type="nucleotide sequence ID" value="XM_060512348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGL6"/>
    <dbReference type="GeneID" id="85396246"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF62">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="54535" checksum="0D3DEB162B376A93" modified="2024-05-29" version="1">MGASEKRSPSVEREEHAIHTVDSVIMDEKPIPQDEENRDWTGSAKKTDPEEIKLVRKLDWRIMPTLCIMYFLNYVDRNAIAQARLNNLEKDLGMSGTEFNTTVSILFVGYVLMQIPSNMLITRIQPGMYMSAWMLIWAVVSGCTALVQNYGGLVACRFFLGITEAPFYPGATYMLSIFYTRKEVASRIALLYCAQILATGLSSLIAAGIFAGMDGLNGIAGWRWLFIVEGAATGLVALFGFWLLPNTPLTTRWLNDRERELAHSRMEKDKLSDSDDKKASAMDGLKQAVRDKRTWLFCLMQNFHLSACSFNSFFPTVVKTLGFNTTITLVMTCPPFIFAGAAGILFGWSSGRLHERTWHITVGLGVAILGFVVAASTLNTAARYVACFIFPMGAYAVNSVIIGWASSTLSQTKEKKAVVLAMTNVGGQIGYIYGAYLWPKSDEPRYAIGFGASAGFALLSILCAWWIRVLLVRENRRIRASTSENVNLYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH80</accession>
    <name>A0AAD8UH80_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_579005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364287.1">
        <property type="nucleotide sequence ID" value="XM_060505192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH80"/>
    <dbReference type="GeneID" id="85389091"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052479">
        <property type="entry name" value="GPI-anchor_Adhesion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185">
        <property type="entry name" value="SERINE/THREONINE-RICH PROTEIN ADG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185:SF1">
        <property type="entry name" value="UPF0619 GPI-ANCHORED MEMBRANE PROTEIN C1322.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041915959" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="182" mass="18261" checksum="5A824413AF1CF17D" modified="2024-05-29" version="1">MFSKTAVAITSFLAIAEAVKVTKPAKGDDWDLSKTNEITWETVSSDPKSFEIVIVNQSGYPEVSETIATVQAADGKYELKGAKVAAGDAYRINLVSVDPQNSGILAQSNEFSFTGSDVTTGSATASASGTAASNASGSGTASGTATGSAASGTSTSAPSSASAIKSTFAIFGSVAVAAYMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHB9</accession>
    <name>A0AAD8UHB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HpcH/HpaI aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_733228</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361623.1">
        <property type="nucleotide sequence ID" value="XM_060512913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHB9"/>
    <dbReference type="GeneID" id="85396811"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050251">
        <property type="entry name" value="HpcH-HpaI_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502">
        <property type="entry name" value="2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30502:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="28305" checksum="6A6781200C7F4AD9" modified="2024-05-29" version="1">MASLLSNSLTRLSASGKLCTAMGIRLVANTQIVHLAANGGFDALFIDLEHSTLSIHDASQHCIVGLQLGMTPFVRVPYQCGNGFVQKVLDGGAMGVVFPHIHGHIDAMAAVSICKYPPQGKRSITSQLPVFSLKAVPQSTIISETNANGSTAFLMIETKESIQNIDEIAAVEGADVLLVGSNDLAIELGVPSQFQSPVFREAMETISRACKKHGKIMGLAGIYNNHELHDWAINELGVRFLLGGQDSAILARGAAETMAEIAKVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIH8</accession>
    <name>A0AAD8UIH8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase MRP protein 1 RNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_629375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362369.1">
        <property type="nucleotide sequence ID" value="XM_060508756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIH8"/>
    <dbReference type="GeneID" id="85392655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000294">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22573">
        <property type="entry name" value="RMP1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047205">
        <property type="entry name" value="RMP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047204">
        <property type="entry name" value="RMP1_RBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37792">
        <property type="entry name" value="RIBONUCLEASE MRP PROTEIN SUBUNIT RMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37792:SF1">
        <property type="entry name" value="RIBONUCLEASE MRP PROTEIN SUBUNIT RMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20945">
        <property type="entry name" value="RMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase MRP protein 1 RNA binding" evidence="2">
        <location>
            <begin position="33"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="300" mass="32294" checksum="EC2746CE92C6CB1F" modified="2024-05-29" version="1">MKATTTTTAATAAKTTPNEETTPIATLVSVLAILDSFNHRNKNQHRVARWWSAFDLLRRVVRRLHDVLEAQARHRRALSFKSKSPSSSSSKKSAVAAGSKSVSSAERRQNALDEDFAARVRMLLDSTIPSSFSAFTQLAADNQHAALGLVLIGLLARINSVVTLLAPTPAPREKATPAGDVTTTSSSSSTNKGATAVAVADERHHQQQQQSDSKGLGVAISRDQLRLAAKTSDHHPLTSSSTPRNFDGASAAISPKKRKLASVPPLEIKSSRPAKEEKPVKKKKKAKKTDDFSDLFSSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UII4</accession>
    <name>A0AAD8UII4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypersensitive response-inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_579917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363913.1">
        <property type="nucleotide sequence ID" value="XM_060505294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UII4"/>
    <dbReference type="GeneID" id="85389193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042238753" evidence="1">
        <location>
            <begin position="16"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="14989" checksum="52AAF6871AD2EBDA" modified="2024-05-29" version="1">MQFATLLASASVAAAAAISKRDVTFKVTNFGADCIPHSTQCSYGFTVIQPGTMETTGVNCTALVPGNTDGTLPDVKEGTCTLSSRTFDVVRSAEGLTLTVSQPVTPSSNQTGSHLLPNSDFEISNQPNAVVQHYTGARSFDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIS5</accession>
    <name>A0AAD8UIS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_583514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362271.1">
        <property type="nucleotide sequence ID" value="XM_060505671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIS5"/>
    <dbReference type="GeneID" id="85389570"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="923"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1243" mass="133563" checksum="33D71DA6B2963CEF" modified="2024-05-29" version="1">MNFPKLTFNPPSGNLTPSPTARSSRDRTASPKRAPACFSNLEPTQDHTANVDMAFSNFDFTTPTKGGAAPVSAATTQPARFAPMSLASPVKKFSTAETPRLKAGATRLSTTMSLDAPTKTPSPKKVSFADASFQSLTASTPKLARNLSPKSSPSKPAVSDYSVMSITSPTASLVSNDRSPRSDSDPNQQQAESAAEEEGHEEEEEEEESHTSRRSGRSPSRDVEEAGGFESPSKLDITMADITMVSDFAPSPQKSKQPYTFATIELSETAKEFSGAFNPETYADFDITSALAPVPSFARQRARIPRKKQRKPRGMVFEKAIAREVAESLAMEELEAAASFRHIATKGGLAYALCPRKRQRVAEPTPEDDSEPYWLEDVDESGVINMIEARRVLRNDLKALPTGPSVHEQRRQYHEEVEKYGEPIVPTCGKRNYDGEKKRAYNNGLLTHTIMAPLLAFPMPELSFDWVLETAIRESNRVHGREQPKHRNVRQPIAIFGESDFSVIEEEEEPQSPTAKLPHFPSTATHHSSSSRKTRLARGAANLEAKLATLQSVVEERSPSPLSSPIRPGFTFTMPSFVSTLEVTETDHEATEVEHEDEPAAVEVASPMVFFKNRSETSPFKKRKSLPAARRLSFSAPLRRASLPAAGSAQLHAVQDLQDPASASLVGAPDSSVELHAVQNPLEVDSASAAAAQATPDRTPSPSPSPVVVDARENPDIFGSFQDHSGSPIQALASLARVFEEAKKTNMDGKVIVSREGGRLIVRFKVSDEHAALFAQEQEPVEELVNAVDSATGPATATALSPIRLNTEADDEKETAEDAKVEAEEEEVAHVPSRAPSPVEEDDDSMVLLREFVTKHNARKAAMATLAEPVEPAEPVVLSPTPVVEPVAAHSSPDPLASAPILMAATPERNQSIWADTPAFSITSSADRSRSARRASPAVSTGRQPLGSLDVNSPSPKKAKRKVDEVDEREASPEKPQPPKRQRRAKADIPDAKKATGKPSDKYADEDEVAPVTNVRTRRQLAVARGEAPAVTKIPVRNKGMSNIRAGEKDLAALTRQNTRNNKGDAISAEEMLEAIKTAPPKIETRAAAAAAKKNNKSVQWAAQLARSQSEDPSTAPIDSDEASSSSAELSPDEEKQVGKVRKARTSTSKIATTKASTAKASTSKAATTKVATTKAATSKTAPAKAAAAKATKASQSKLATAPKTEGAKVSKTVKKPTAAAKKELGLSANGTPAKRSARTVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJT1</accession>
    <name>A0AAD8UJT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_720930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363104.1">
        <property type="nucleotide sequence ID" value="XM_060512324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJT1"/>
    <dbReference type="GeneID" id="85396222"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="16"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="30907" checksum="5688337867E268B1" modified="2024-05-29" version="1">MNAGVRIHFYVTGQGPLMVLLHGFPDNSRTWTHQVAEFSKTHTIVCPTLRGYPPSDIPTVDQDAYSLQTVVGDILAILDHFNAAQAIVGGHDFGGAAIQLLALHHPERVSGLIIMNSPILPRFHELIQFDKEQQAQSAYTIRHIQYQKGDDKNLGAALEGIKDDEQRREMHDYLSESPMEGMYAYYRYNYPGPPYGQHVDTSGMIYQVPALIIWGFADTYFSTKFLDGIPKFFVNTVRLVTFPGAGHWVFREQPDRVNQEIRSWLRVLDNLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKC3</accession>
    <name>A0AAD8UKC3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Semialdehyde dehydrogenase NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_623069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364442.1">
        <property type="nucleotide sequence ID" value="XM_060508357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKC3"/>
    <dbReference type="GeneID" id="85392256"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="23320" checksum="E4BD5EE1AE8BDE47" modified="2024-05-29" version="1">MSSPIRNIAIIGATGQMGSQIAKTLLESGFNVTAIQRSDSTKTVSSGVKSIKLDLNDVSALTTAFRGQDAVISAAPDPIVLENQKPWIDAAVAAGVKRIVPSEYSTNVDSPLAEGLPIVVDKVRARRYLIEKIAENGNKSSWMSVNNGPFFELVLGFGGLGPNFRSKTAKYHNGGDNLIGTTKRRLPRSCVMTEDCTRRPRISPCISTRRRSVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKK0</accession>
    <name>A0AAD8UKK0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_578573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364562.1">
        <property type="nucleotide sequence ID" value="XM_060505142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKK0"/>
    <dbReference type="GeneID" id="85389041"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="26409" checksum="813884D8EA1421BE" modified="2024-05-29" version="1">MAEVLGVVLKKLWDQVHDTPSEIGQLVAQVELLNAVLAEADAMSDQVYSTNNNPSVISLNYCQHAVNHLETLVTDLQQQMTMANKPRRSIARLKFTLKKDLIQNCQNKLQVALQMVVLSQNTRILPHSILSGVQGRYFFCPIYRARVRPPMWMSERIWDIQTYRACAGWKFSLRTWTVRPFSAPVFGYVKSGSWSQVLQEFEGNRASVFDRDSEGWSLVHVCGPHMRRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULL2</accession>
    <name>A0AAD8ULL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dethiobiotin synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_617182</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366166.1">
        <property type="nucleotide sequence ID" value="XM_060508012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULL2"/>
    <dbReference type="GeneID" id="85391911"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000080">
        <property type="entry name" value="Bifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="801" mass="87054" checksum="88F282E40E5F59B2" modified="2024-05-29" version="1">MAPVGALLWRSLRTYQIYGANTDVGKTVFASALCNAARNFWPQDKTAFLKPVSTGPATEADDSHISRFAPGIAKKTLFQFEIPASPHLAAAASDQPTPSDNEVLKGIYNYSSSRAADGPGWLFIETAGGVHSPAPSGTPQADLYAPLRAPVIFIGDAKLGGISQTISAFESLKLRGYDVESILLFRDGYYQNDTYLTDYFRRGHGIPVTAVDQPPARAQDEQADAAAMSRYYTELSSSTAIKDTLDHLHARHLARIARLETMSRDAHEIIWYPFTQHKGLTPDKITAIDSAHGDNFQTLVPQSQQQPGDQALLQPSFDGSSSWWTQGLGHANPKLTLAASYAAGRYGHVMFASAVHEPALALAQTLLQGLRNPRLSRVFYSDNGSTGMEVAVKMGLRAARVRYGWEASDKLEILGLRGSYHGDTMGAMDSTEPSVFNEKVEWYDGKGFWFEYPSVMCKDGKWQVRVPGVLKEELGAGQEFGSLSTVFDVAGREKTGEAQVYEEYIVSVLRRLRDQGRKFGALVMEPVILGAGGMIMADPLFQSTLVKVVRQHPELFGTATQSSSAADENTWTGLPVVFDEVFTGLTRLGRFSAASFLGVDPDVVCNAKLLTGGLVPLCTTSASDSIFRAFESDEKSDALLHGHSYTAHAVGCQVALESLRELQRIDRDGEWNWAKTNGWGASATANSSTQVESGSSAEAWSVWSQSFVDWISKQAGRVDGVWALGSVLAIHLQDSEGAGYSSNAAANLQSALLQGEHGAEGGRWNVHSRVLGNVLYVMTSQTTTQEDIERLENLLRRSLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULY6</accession>
    <name>A0AAD8ULY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_574861</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366331.1">
        <property type="nucleotide sequence ID" value="XM_060504749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULY6"/>
    <dbReference type="GeneID" id="85388648"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041783033" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="20"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="55198" checksum="7AD4AF643ED9B4BD" modified="2024-05-29" version="1">MRAFAIAAGLLSLLSPIVASSDSTTAADKVSKVNLPANFKPPQVFKNANLVHIVSLEKNYVKESINVLIENIDKQPQDAYYLPFTPEQMSRIGGFEAKDRKNPEAGPFAVDAVEYDPLSETQYYKIQLPTPLKAGGQQTLSISYYLLQAYKPLPASIAQEEQQFLTYDFSVYAPSAYVTSKQKTELKSHSSNIPDYTKLPGSGDIKEFPQKQGAKLTYGPFDEKPAGAVSPAHVRFEFTKPVTHVAQLDRDVEVSHWGGNVAFEERYELYHRGANLSKLFNRVKWAQAAYYNPNTYALKEMKFPLKVGSADPYFVDAIGNVSTSRFRSNKREALLEIKPRYPIFGGWKYPFTIGWNSDAKNFVRTVEAGKYVVNVPFLEGPKQPEGIEYAKVNLQILLPEGATNVKFYTSIPESSIVDSAISVHKTYLDTVGRTSVTIKANNLVDEFRDREVIVSYEYSVSSALRKPLVIFVSFISLFAAAWLVGGLNPKISTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULZ0</accession>
    <name>A0AAD8ULZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_623428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364289.1">
        <property type="nucleotide sequence ID" value="XM_060508383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULZ0"/>
    <dbReference type="GeneID" id="85392282"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_bS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_bS16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="125" mass="13786" checksum="C3F0372E48933762" modified="2024-05-29" version="1">MVVRIRLARFGRVNQPFYNIVVTQARTARNSKPIEVIGTYDPVPRQDPYDATTKPHKDIRLDSLRARYWVGVGAQPTETVWRLLSMVGILQPKFRPNGTANTATAAKSLRTPASPAKAAAPAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMC1</accession>
    <name>A0AAD8UMC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxalate decarboxylase family bicupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_623801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364233.1">
        <property type="nucleotide sequence ID" value="XM_060508403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMC1"/>
    <dbReference type="GeneID" id="85392302"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033609">
        <property type="term" value="P:oxalate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20305">
        <property type="entry name" value="cupin_OxDC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20304">
        <property type="entry name" value="cupin_OxDC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017774">
        <property type="entry name" value="Bicupin_oxalate_deCO2ase/Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051610">
        <property type="entry name" value="GPI/OXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03404">
        <property type="entry name" value="bicupin_oxalic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848">
        <property type="entry name" value="OXALATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35848:SF9">
        <property type="entry name" value="SLL1358 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042297890" evidence="5">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="118"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="6">
        <location>
            <begin position="297"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="53329" checksum="B543CF850175DFBF" modified="2024-05-29" version="1">MHFTQPTAAKLLLLWASASELCSAAPHFDSPRERLLRGMDIPASYKKKSTSNPYVPGFRDPNDGAVDSVGDGLDPLPYRNGLGASVLGPWNSERSRQNPDMVRPPSTDKGNMPNMRWSFADSHIRIEEGGWTRQTTVRELSTSVELAGVNMRLGEGVIRELHWHKEAEWAYVVDGEVRVTALDYEGGNFIDDLKKGDLWYFPSGVPHSLQGLSPNGTEFLLIFDDGRFSEESTFILSDWLAHTPKSVIAENFHLEPEVFKHLPEGEKYIFQGTLPGPIDEERPKGKHAKKSRFNFTHRMLDQKPEQTSGGEVRITDSKNFPISKTVAAAHLTIQPGALREMHWHPNADEWSFFIKGRARITIFAAEGTARTFDYVPGDVGIVPKNMGHFVENIGDEPIEMLEIFRADEFRDFSLFQWMGETPKKLVIDHLFKDDKENGEKFWNQVKEAEKDPITKFQKDTGSSQSERVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNB0</accession>
    <name>A0AAD8UNB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major royal jelly protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_620556</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major royal jelly protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365190.1">
        <property type="nucleotide sequence ID" value="XM_060508199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNB0"/>
    <dbReference type="GeneID" id="85392098"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017996">
        <property type="entry name" value="MRJP/yellow-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10009:SF18">
        <property type="entry name" value="PROTEIN YELLOW-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10009">
        <property type="entry name" value="PROTEIN YELLOW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03022">
        <property type="entry name" value="MRJP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042049447" evidence="4">
        <location>
            <begin position="21"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="424" mass="45852" checksum="923BE4B4EE616638" modified="2024-05-29" version="1">MISLKLTLVAALAGLHPARAQNLIFDSGRSGPSLEVVHLYNDQWPTGVAVSSTGRKFSNYPGGLDPNNTNDGTNGKYTVAELFDNNIEKPYPSAEFNNPPGGAINFTTTPPAGANYKNYLIGVQSVVIDSADRLWILDTGRVLTPQGVLVPASVGGAKLVGVNLTTNSVIKTIVFPNTVAYPDTYLNDVRFDLDPSLTSSGEGVAYITDSSSEGRTGLIVVDLGSGESWRHLDGSPYVQGDRQFLAFIWGRELYANQAGNRAGHLTFGADGIALGKDGKTLYFGGVGNRYLYSIPTERLRDNSPTSEIQAQAAVVTESQRGLSDGFETDTNGFIYHGNFEQNAINFFNPENGTDQVFLRDPRINWADTFSVATDGFIYFTNNQLAFGPAVYPGTDSRQRPFSLLRARLPNNGTKVGSKMNMTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNI2</accession>
    <name>A0AAD8UNI2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial distribution and morphology protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial inheritance component MDM10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MDM10</name>
        <name evidence="7" type="ORF">BDZ83DRAFT_572274</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion outer membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MDM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNI2"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03102">
        <property type="entry name" value="Mdm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027539">
        <property type="entry name" value="Mdm10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12519">
        <property type="entry name" value="MDM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 6" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="431" mass="47396" checksum="12F5436916FA0CE3" modified="2024-05-29" version="1">MREFMSYVQSAFYDATGWNRDNSYSTLNATADALLNFPTPQGLRLTLSSLATPHFATSYQLGSVGVVDGSISYLYSSVPLRAHLTPQSDAIPLPALLRSYRPLADLPPRTSKPYPLLSPAAASLLYGRLYLPESMLEALVVKKISPALQLQLSAVSGKFLRNGGTVLGLAQYDVGRYAIEGLGSSDGGLLGFRGAYNFGGDTEDIQALRSGGKLGGHTDEAKERIYGRFSAGGEIYYGLLNKSGGVSFGGRFATLPEHRGTPLTATMTINPLMGNISASYAVVAGKHCSLATRMDFNVYSYESDWSVGMELWRKNLTRNLEPALSAESFVKKDRSFQAKLEWRLDEEHEAPQLQPRLVVEEPKQERQNKPRERSFQAKMDVIKARLDQNMKIGVLWEGRVKSLLFSLGSAIDLRKLDSPFRTVGVEIQFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPK1</accession>
    <name>A0AAD8UPK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_137451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368292.1">
        <property type="nucleotide sequence ID" value="XM_060501257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPK1"/>
    <dbReference type="GeneID" id="85385156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="24312" checksum="2622ED9DC7A3BCD3" modified="2024-05-29" version="1">MAAKQSKSGPPGPQIGMSRDGAGGQALPMSRIDSFLFSPHTTTAAFTKDQYVRYEVHVRLWPCRKHPSGFISKVKLLTHPVPGKATSTVTESCAHDAMLSSGSLSRFFFLYSILRTTSSYSSTPVYKRPRLYAVSVAKRQHRPRPRPRPIRIPTCRVPRYVPWTTIDYGPVFDTIRAKDYRRGFAASNQGSWCTLVCGPAVRHNDGRMLRRTGRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPQ5</accession>
    <name>A0AAD8UPQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_751499</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365714.1">
        <property type="nucleotide sequence ID" value="XM_060514058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPQ5"/>
    <dbReference type="GeneID" id="85397956"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="29883" checksum="8DC7EA2CF908595B" modified="2024-05-29" version="1">MPQNEYMERWRKLHGRRLDHEEKARKKEAREGHKASKDAQNLRGLRAKLHAKKRHNEKIQMRKQIKAHEERNVKTNDEKEPSEPMPAYLLDRNNPSNAKAISSQIKNKRAEKAARFQVPLPKVKGISEEEMFKVISTGKKTHQKSWKRMITKPTFVGPNFTRRDPKHERFIRPMGLRYKHAHVCHPELNVTVKLPILGVKKNPQNPLYTNLGVLTKGTVLEVNVSDMGLTTASGKVVWGRYAQVTNSPENDGCVNAVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ89</accession>
    <name>A0AAD8UQ89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adipose-regulatory protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_307422</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365284.1">
        <property type="nucleotide sequence ID" value="XM_060502291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ89"/>
    <dbReference type="GeneID" id="85386190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="289"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="380" mass="41325" checksum="A9965AD56C0D834E" modified="2024-05-29" version="1">MEVLSKASRVATSKTAQRTLVNVSLLVGTSLFLLPFAAIASILFFRDYLPEQVVTTPVHLQYGSGANPFGTASIPTSALRTQQEYDVSVTLSMPRSPANTQRGNFMIAIHLLDIGALSTGSDKIQPHIAPEPYAHFDGKTVLLSSRRPALVPYQDPMVSIASRILFLAYHVLFSDSETCVLTVPMAERVELAKGSSLPASAYLELQGGQDIETYSASITLTAQLRGLRWLMYNYRVMTLTAAVLLFWTSEIIFMAVAWLAWSGLSRSSQGSGIGNGGIVEKSYNKSMGQVKREDGSGIDELSDAPRTFPTYGNQAPLRYEPEVKDEQHAGPRMEDLLPLGGEADDEEEDDGRGFRGDSGIGTSYSEGGSSSVRRRSSHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQB6</accession>
    <name>A0AAD8UQB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_170728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368086.1">
        <property type="nucleotide sequence ID" value="XM_060501468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQB6"/>
    <dbReference type="GeneID" id="85385367"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="24137" checksum="531A9EB799E3566E" modified="2024-05-29" version="1">MLVSWCLLFPHRRRPISLLSASHFIVHSWVPQYYSLLQRKTSLSLSVSLSLFLSLFQPHSLNYTTLIHCAFSPRPALTNSAWPGGAACELESYQKKKETSTGLITTDDNASSAHPYSFPPHLSSYLRCLPYLTPHLSCSLPLSRPLSLSHLALPYITYLHFLTSPDLRTHAHAHYTYARPGPLGPRPPTWTWTGPGPLTCTGTCNLSCVPPPSSIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQC4</accession>
    <name>A0AAD8UQC4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione hydrolase</fullName>
            <ecNumber evidence="3">2.3.2.2</ecNumber>
            <ecNumber evidence="3">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_608914</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="3"/>
    <dbReference type="EC" id="3.4.19.13" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368742.1">
        <property type="nucleotide sequence ID" value="XM_060507500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQC4"/>
    <dbReference type="GeneID" id="85391399"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.130:FF:000001">
        <property type="entry name" value="Gamma-glutamyltransferase 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.40:FF:000008">
        <property type="entry name" value="Gamma-glutamyltranspeptidase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF62">
        <property type="entry name" value="GLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042218893" description="Glutathione hydrolase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="393"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="445"/>
            <end position="446"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="60198" checksum="266DA5A26DD12BE8" modified="2024-05-29" version="1">MKFSLTSAALAQLLLGITTQPALAAPSHSTIPKLGAVASESDICSKIGTELLKKGGNAADATVGTVLCVGVVGMYHSGIGGGGFMLVRSSNGTYEFIDFRETAPAAAYENMYTNNTRASLYGGLASGVPGELRGLEHLHKKYGKLPWSKVVEPAIKVARYGWRVNEDLVRYMKSVTPNGNFLTDDPSWAIDFAPHGTLLKLNETITRKRYADTLEVIAQEGADAFYTGAIANATIAALTKSNGTMTMADLKNYTVAIREPAQISYRGYKLTACNAPSGGIVALSALNIVSGYEGFGDPASRNNTVHRLDESMRFAYGQRTKLGDPSFVDGLSAYTKSMISPEVGAEIRSKIFDFRTENVSYYNPEGIESLETPGTSHIAVADASGMAISLTTTVNLLFGSQLMVPETGVIMNDEMDDFSTPGSSNAFGFIPSPANYIRPGKRPLSSISPVIVEHPDGKLYFVIGSAGGSRIITATIQNIHNVLDRNLTVTQALAEPRFHDQLEPNTAAFEYAYDNSTTSYLASLGTNVTWVAPGGSTAQGVRLLPNGTFEAAGEPRQKNSGGFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQU4</accession>
    <name>A0AAD8UQU4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_266754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366254.1">
        <property type="nucleotide sequence ID" value="XM_060502028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQU4"/>
    <dbReference type="GeneID" id="85385927"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042188056" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="45611" checksum="D19C9FB53644341D" modified="2024-05-29" version="1">MSRLRNCTRAAVLSILIASAHAASIPSVFGRQDNTCAASGFTSCGNGLPGNFCCGMGKKCITLAGNTTVLCCPEGESCDRISPITCNINLQDPVAHPDASIKTTVLNGKLATCGDSCCPFGYSCNSLSQCTKDSDQTKAPEEASTPVPKPTSTATAVPSVIPTTIAASTTPAGDNNNNTNDNGDSDNKNGTFPTAIVIGSLVGLLVGVGLGVALLLFCARRRRRGPPPLSEKERGGSGGPRPSTSTSSFGNIISEPIPITDHATVRTDFILKTPSTTHSRSRSDSGFVTSPAGSTPNKGHNRLSSTATTLAHHPIGLARSDSAPRTPPGRGAGTGAVAPIRGMRPNSGSRRLQPPNVPNPLAPPKPGYINNSNNQSHLQREPSSESISVFADPRTVGGRPGVKRNTTFTEMMEEAELGDVRRGKPYVPYTPQMPSQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQW9</accession>
    <name>A0AAD8UQW9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_749608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367858.1">
        <property type="nucleotide sequence ID" value="XM_060513782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQW9"/>
    <dbReference type="GeneID" id="85397680"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="61" mass="6506" checksum="C2ED5FD020766902" modified="2024-05-29" version="1">MPGKSHATPLNQPIAVPSVAAVGNLVGSSIKFPRTRHDGESVDYHTGDPFIGGWFNRSTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URC9</accession>
    <name>A0AAD8URC9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EC29 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_611024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368113.1">
        <property type="nucleotide sequence ID" value="XM_060507634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URC9"/>
    <dbReference type="GeneID" id="85391533"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042136203" description="EC29 protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10710" checksum="1FEB5A3C2FDA25B6" modified="2024-05-29" version="1">MFSHTLVFLAATLAALAQPALGLPTEQLDARQTVCSINEKTWTATMTGTCSIDGGPAMTCDQRTDLKTLVVKKNTMLSASGLGNNKFECKGYQSWQCCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URF3</accession>
    <name>A0AAD8URF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_751450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365869.1">
        <property type="nucleotide sequence ID" value="XM_060514050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URF3"/>
    <dbReference type="GeneID" id="85397948"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050917">
        <property type="entry name" value="SOX_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803:SF5">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="116"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="116"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="175"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="46966" checksum="94C8E01F1BA43136" modified="2024-05-29" version="1">MSGDLSHQPYSTPDTSPPTPSRPPDGLTTRSGLNIQKGSTTIKPLAVRASRVEKSTPKKKKERAKSAKKVDVVKSPLSELAKEQPHIPVADIGAYVQRSSEIRMKEVEESKTPGRIKRPMNAFMLYRKAYQNLAKSLCTQNNHQLVSQVCGAGWPLEPEHIRDQFNEWAKEERANHQLAHPGYKFTPSKPRPKAREEEDSDQGDMDDMEWNGSRASSRSRQVRKPGHGRNEAPASIFHNYPPLQTSPMGLGVQTQSMYHYSNPGKPLPAPYSQNGLGGGQYYQQSVHQRQDATGFVEDVLIRKTPSPAMGYAAPSMDHRYDGIDHYGPMSHPDGIDPIIDPGLMGHGGHPYGDMYGNHMLPRWTNPLNFGDGRQELIDGMGYEESLLTDPQIQILRGPESSWRVEELDSSHFTNSWIEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USB5</accession>
    <name>A0AAD8USB5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="3">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_113959</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368653.1">
        <property type="nucleotide sequence ID" value="XM_060501111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USB5"/>
    <dbReference type="GeneID" id="85385010"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006043">
        <property type="term" value="P:glucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000002">
        <property type="entry name" value="Glucosamine-6-phosphate deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="10">
        <location>
            <begin position="8"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="366"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="47377" checksum="DB40C176CBBC5ABA" modified="2024-05-29" version="1">MRLIIRDDAEAASAYVANYVVDRIKHFNPTPAHPFVLGLPTGSSPLGVYKILVQKYKAGEISFENVITFNMDEYVGIPRDHPESYHSFMWKHLFSHVNIHPQNVNILNGQNPNLEAECVAYESKIKAVGGIDLFLAGIGEDGHIAFNEPGSSLASRTRVKTLAYDTILANSRFFGNDVDQVPRLALTVGVQTVLEAREVVAIILGAKKALALQRCIEQGVNHMWTLSSLQLHPHPMIVVDEDATLELQVKTVKYFKSIEKVAREQGFEQILPSKIRTGPSPPPIPITRIDEVDTPTILHPQPTTSRLLRASPATEYPVRSRSTSPDIELVFESMASRTKTPSEQQLRAVTPDLVTDRMAERIPGVPAAVTGRLTPNPEKQQTSTSISRSATPELVPDRMASRIPEPALARRLTPNPEQQMMSRVNAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USP7</accession>
    <name>A0AAD8USP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maintenance of telomere capping protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_615841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366469.1">
        <property type="nucleotide sequence ID" value="XM_060507925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USP7"/>
    <dbReference type="GeneID" id="85391824"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018814">
        <property type="entry name" value="DUF5427"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28265:SF1">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10310">
        <property type="entry name" value="DUF5427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="55228" checksum="EA24887B92F2F596" modified="2024-05-29" version="1">MASKKTKPAAAGDDIDDLFDGIGDNVAPPKKSLEKKPKPTTAASKAMADNDILAELEKDLEQPSRPHTPRLKETAAKGIPKRSATPTTDDKSTAPRKSTDSARSLRASFTPSATSSDLQEPEKRPAEQLATASSSAASPEAAPAAAAGGGWWGGIFNTATAAMKQAEAAVKEIQKNEEAKKWAEQVRGNVGGLRALGDNLRQQALPTFTNILHTIAPPISSHERLLIHIAHDMVGYPSLDPLIYGTFSRVMSQVEGGELMVIQRGQETHSRRYSNDGGAGWRDGPWWRQSDSPRDLGLIKGLTEGTKLCRAGAEGYASEYFAAHGGVEQARLRATEPVSEDNPVRSSDLFLAIQAVGTTADSGLFARTSAVEKEKETSAVAEQDEADEMVCFAVFCLDPVHEIEYSAISQSIPAKWIRWLDAASPLTPASGEDGQEGSLGQSIPDEIREIVEGGGVDPREWVAEWIEELLSLAVGIVAQRYVARRMGVGEGGIGKGKRRMDELVQDGGGEAARAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT18</accession>
    <name>A0AAD8UT18_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_729042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367293.1">
        <property type="nucleotide sequence ID" value="XM_060512809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT18"/>
    <dbReference type="GeneID" id="85396707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="25742" checksum="4870833340F93B3A" modified="2024-05-29" version="1">MRYFEGLQRCSNWELGKLSSTKARMEISTVLWQLGIDGFALVHVACDDELAQGRNFAPEIDKLLSSPLGRHVGKIVVYLQSLAECCRYSISSSHLQAAVEISPKARARCSFATLTVKLHDLFNRYTVQTEGYSHDSWVFEVEVGNPEESAVGENREVRILVSFCLPLSNWRFPTFEIGPGSLSVKPSQFSFFEQNEPAVTSACRAPLNIQEVVGQFEQPKTRSQTTDSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTP5</accession>
    <name>A0AAD8UTP5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_570058</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368702.1">
        <property type="nucleotide sequence ID" value="XM_060504262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTP5"/>
    <dbReference type="GeneID" id="85388161"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="102"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="32711" checksum="3294C2D7ED26E5D4" modified="2024-05-29" version="1">MATKLYRSRALAGLRNCRPSEIRSFSTSIPQSAGFPTGFPKDAENMRKSPREHIGTLKAPLINPADKYGSKADNLHKYGSWIMGCLPKYVQQISVWKDELTIYVSPSGIIPVFSFLKYNTSAEYTQISDITAVDYPTRDQRFEVIYNLLSVRHNSRIRVKTYADEASPVPSVTSLFDGANWYEREVYDLFGVFFADHPDLRRIMTDYGFEGHPLRKDFPLTGYTEVRYDEEKKRIVTEPLELTQAFRNFEGGSSAWEGVGPGTDRRPDTFKLPTPKPEEKKEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUF9</accession>
    <name>A0AAD8UUF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368805.1">
        <property type="nucleotide sequence ID" value="XM_060513680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUF9"/>
    <dbReference type="GeneID" id="85397578"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="245"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="747" mass="83581" checksum="661849EC85C89C41" modified="2024-05-29" version="1">MAPPGQLPRVRSAEASIEKGRAAYAEQRFRVALEHFTLVAGNCPCSSPSGGGPTSSSAGSGSSSGGRTSRGVKGLGAAGSGGGGGAGLDGGDASGNGHSPAQQRRRRERCTCRDFAQAAARHRRERGSVYAEATKECKCGAEKTWGRCHREGHIQALDYRAACFEKMGKLDMARRDAEWLLEIAPRRLEGYMRLGKIYKLEKKHEMAWAAWSAGIEVGRNEGLTRTTKFEQLCRIREPLHKHFYRRDPMDLPIELIEKVFSYFDLHELCRISGVCKRWDQFLDTHPYIWRQVHFPSLNPQKPPRVSFLKTLRKRTGGGARSLVIPNAHAFQLNESKWLSLIQTTNPRMTTRLEIGAIKRNLEGGDWGYKLPPKPLFFEGLTHLGFSFRVDKPNYQSSGGAQPFVRQFVERARENIERISLFSMHLNDLGWPELPRLKILQLTGPLTSTLNQLTPERRIDPFALARSTPNLEQIHMDNFGVFTGLDSLAPPEDCWSLWPGLQVIKLGKACGALSMGDKRHFPPLHPSSFRVLDARAALQSNHGDWLPQQLPLDYSGYEAAESLVTYPNLERFWMPKLPLSVDLATVLLEPAVRSGRLRELGLCWRQEPGQFFPGALDWLRGSISVRTFGFFNFDFESHENLTRDPAQRGRGIDSVDLLFGFLQSFPNLEVLELHSDLCDPMRLGAVIERVAILGRLKKVYQRALTGVAMDQLRTFCGAHGVEVVYGSWEAEFPVPLESLAPVEAEIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVQ2</accession>
    <name>A0AAD8UVQ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_716896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368624.1">
        <property type="nucleotide sequence ID" value="XM_060511890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVQ2"/>
    <dbReference type="GeneID" id="85395788"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17303" checksum="74FF0BE7EB29AF01" modified="2024-05-29" version="1">MATTTSNFFPLATETYYPDSPGDASSSGNGVDTEAGASGDSPGAVNLSREAMIAIIVVVSVVGALGIGMAVLFYVAKKREWKIRETMRKSARKVVTALTPRRTEFPRSVKESSSPPRSHRGRARLDDVPPTPRLRPEDLEKGLKEAESKRKLMRWGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X810</accession>
    <name>A0AAD8X810_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Catabolic 3-dehydroquinase</fullName>
            <shortName evidence="3">cDHQase</shortName>
            <ecNumber evidence="3">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-dehydroquinate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">qutE</name>
        <name evidence="7" type="ORF">BDZ83DRAFT_644673</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis; 3,4-dihydroxybenzoate from 3-dehydroquinate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homododecamer. Adopts a ring-like structure, composed of an arrangement of two hexameric rings stacked on top of one another.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000268">
        <property type="protein sequence ID" value="KAK1704191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X810"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046279">
        <property type="term" value="P:3,4-dihydroxybenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019631">
        <property type="term" value="P:quinate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="entry name" value="Dehydroquinase, class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003804">
        <property type="entry name" value="PRK05395.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003805">
        <property type="entry name" value="PRK05395.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003806">
        <property type="entry name" value="PRK05395.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003807">
        <property type="entry name" value="PRK05395.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272:SF3">
        <property type="entry name" value="CATABOLIC 3-DEHYDROQUINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="Type II 3-dehydroquinate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3 4">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3 6">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1704191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="148" mass="16055" checksum="F78FD2C91706968D" modified="2024-05-29" version="1">MAKSILLINGPNLNLLGTREPHIYGSTTLSQLETQSKEHAKSLGADLQSFQSNTEGAIVERIHAARGNVDVIIINPAAYTHTSVAIRDALLGVDIPFIELHISNTHARESFRHHSYLSDKAVAVIMGLGIHGYGYAIDHAVKNIKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8S7</accession>
    <name>A0AAD8X8S7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_595440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000293">
        <property type="protein sequence ID" value="KAK1703026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357222.1">
        <property type="nucleotide sequence ID" value="XM_060506795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8S7"/>
    <dbReference type="GeneID" id="85390694"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF14">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel protein Msy1/2-like transmembrane" evidence="8">
        <location>
            <begin position="38"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="7">
        <location>
            <begin position="448"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="660"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="662"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1703026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="731" mass="83437" checksum="A20C628C7C13A5FC" modified="2024-05-29" version="1">MKASSAAEGHQTPENSEAPPLPLPPVIIAQYRKRLVWWAVRYCIIVIVIFVAFLIPLITLSNDADFADGSTPQSIQDKQYRNLVYYISLWLEVTWVAAVFFDLLGLGLPYLFRFLARYINSSHQRYWRILKFMRRPICFLGTTIVTFIFFAACINTNELLAVNVNKDPNTFGWDDVVADILEQATLWVAFYFVEKILISYISVHYHYRANHFKLTRTKDLQNALITLYDASTYLHPFHRGTFDEEDMIIRNANGGSHKQERMRVSSYLARLGLDGYKLVGLFGNFISDDPHAHWMRPASTYAIIERAWGNEDSATALARRIWFSCVTQDKFGLTLGDIKDILGPHRASEATKIFATLNDGQGHDIRLEEFTAIVREAGKTRQDIYHNINNMDHCINTFDWFCLFIIAAVMIFFIMIAYVPAMKEIQSVLSSLAIGLSFAVGRTFHHLLVGIVFVFFDHPYDIGDVINVCNAGATAGIACTVKRQSLLYTVFRRLDNNCDLQISNEQLTQKRVENYTRSGINRQGMSLFVDFRTSFTDIMRLRGILEEFLAQNSRDYVPETLGLNVASLHELNKMELRIAFTHRNNWSDDKLRSQRSNRFHCALVSACRSIPLYKPGGMSPSAGENGNPMYTVQLDTSNELQENIKKEQTRRHGLRWDHVEQDSNQVQNQPLSNNAEVGRTEDKTKTDKAKEQEAFLKLARLTMGNERIGASTGVDLPASRTGLRQSRRPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9X5</accession>
    <name>A0AAD8X9X5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_146015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358496.1">
        <property type="nucleotide sequence ID" value="XM_060501306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9X5"/>
    <dbReference type="GeneID" id="85385205"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="22433" checksum="1E6EE831A3062B54" modified="2024-05-29" version="1">MPFLKPAPRSANIRIEIMAKVKINVLKPVSSGVKKSGHVTESSPAAKGKSLPKAAAKTSAKVTKKTSDEIKAKSTEPKSSKAKNDLKPKSKGKGKDKNPASKASGDPAPIPSSTKTSNRVTKRTKKTKELPKGLVAIGFFGSAAATHRAQLGAGKSNVRLLPTALPVPLPPKKGGEAGEGVAKGSAEPKKTKKVTIATTGMTTPSPTPSRGSSVSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB66</accession>
    <name>A0AAD8XB66_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6590 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_539326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359876.1">
        <property type="nucleotide sequence ID" value="XM_060503388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB66"/>
    <dbReference type="GeneID" id="85387287"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046497">
        <property type="entry name" value="DUF6590"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20233">
        <property type="entry name" value="DUF6590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6590" evidence="2">
        <location>
            <begin position="56"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="193" mass="21819" checksum="BC08F4C956B2A26A" modified="2024-05-29" version="1" fragment="single">MVIGNRDFSTFRSKSTKSTKSDSGNGDDASIGTHESSYEHPLARKGYDIGPASRCEVGDVFEFLWADSHEFEWEWKCLGYTRFIVLRHSDTFPHYCHCVPISTPTKNDFQKPGIDSSQQGYVFDENDRTPPFDRLPFSPVGMQLRPGKFRVKENSRANYADVLEIDHDAQVMVVGDYRQGKLVGKKGAKLEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBJ7</accession>
    <name>A0AAD8XBJ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_641257</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358583.1">
        <property type="nucleotide sequence ID" value="XM_060509544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBJ7"/>
    <dbReference type="GeneID" id="85393443"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="240"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="952" mass="108150" checksum="18C9B0361FCD395B" modified="2024-05-29" version="1">MAEILGLTASIIATIQITESVIKICKGLIKDIRDAPSDFRAILIETTSVAAVLQTLEFVIDVEEPDSNLRKALEGSSTSGKGSGPIQECHCIIVQLAKLLPAGHNPEESQDSKGKRFQAVKRSLAWPLDASKAKKLLQDLGRCKDTVSFALTATSINDVKRIQQVLTGRFRLRLEDALSLIHIKLILLKLENQRNEVHKWLKHTDPSNIHRDACKNHEPGTCEWILRVPEWAQYEQGDIRCLWIHGMPGAGKTILASQLANKIEKSCAQSNLNGTVSIGINYYCHFGRNQDESAPFLQWVLDRMCKKVKQVPDILWDMFEDGGEPDPSDLLNAVEAVSHYFSSVFIMIDAVDESSPRDELLSVLRDLATDHRFAKIRLLVASREYLDIERVMREISTEVSMRNAELDADIRLYTKNRLTVNKSLRTWPEDLRAEALEALTIGAKGMFRWVDCQLDALRRIKEDKTAVRKELKNLPKDINKAYNRIFEMMPEEDRQVVASFLDWICFNYKVFKQEAIGCGVLLEATENYLDRQDSFTRDYRFDVELLQEMCGCLITVRTMESNDCPPGGEVEIKLPHYTVMEYLAVSNRFGPDYCFRLDKDATLGLRAGILLLEGFRSPVEEISIMRPKYHEQAPGQSWRLEFQTYCAISAIKLISANEEAILKHEELATLLTTPHQSRLHPVDVARRLDRKYYDLAEYLIEKYDVDMTFWLVQPSISSPQEVRILLDLLHMGAFNLVDFMLSRVHDAKTLFQTMIEIDYVFPDQERGPRHFHVSLISFIATISARDPSPLRHLLKTWSQTFDCRIALLNYVMWHHHEKKNGGKNAPCSDWCTLQELLSLGAEPDSLEFIITPLQIAVACLDLEGVKVLLKCGAQPNAAGNPGVMDRPEHFVLRQFDFLSGMTPLKICDSGFQDACLRKAWFEYGFDDGIMNTRLGQGSSGQIRAVLCEYGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBK7</accession>
    <name>A0AAD8XBK7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_757725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000180">
        <property type="protein sequence ID" value="KAK1709702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358613.1">
        <property type="nucleotide sequence ID" value="XM_060514933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBK7"/>
    <dbReference type="GeneID" id="85398831"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000153">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="174"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="47344" checksum="EE1EF0842B963D8A" modified="2024-05-29" version="1">MLPDKDLSLAIVGGGIGGLCLALYITTHTRIPVTVYENAPKFGEIGAGVAFGPNAVRAITKISEPLAAAVEARANRNIFADKENIWFDFRVGMDSANETARARGVVAGTYLCSVEHPQPGSWMVNRSHLVDEIAKLLPNGIAQFSKTLHDIDDLGDDGVVLKFGDGTSARHSAVIGCDGIKSQTRRIMLGEDHSATNPSYTGKYCYRGMVPMNKAVELLGEEKAKNCQAYLGYHGHMLTFPVAGGRMMNVVAFQSSKEWPHKTMVIPATKEQMLQSFSTWGPDVLNIVRLMGQSDIWALFDLSPMENYHKGRICLLGDAAHASTPFQGAGAGMAVEDAYVLGRLLYNVRQAQDLLGVFKSFSRARVERTQKLVATSREAGYLWHFEAEGDDLGKIKEIMRNRMSWVWEKDLDDDIAQVTTDPREQMLKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBR1</accession>
    <name>A0AAD8XBR1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Translin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_464716</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361432.1">
        <property type="nucleotide sequence ID" value="XM_060503251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBR1"/>
    <dbReference type="GeneID" id="85387150"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14819">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.200:FF:000002">
        <property type="entry name" value="Putative translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1719348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="256" mass="29008" checksum="BDA43D494C153C3A" modified="2024-05-29" version="1">MDSDTNMVEVPASRLLDPQIFEHLKNKIEEDQEVRDQMSQTVQKLDRAISYVQGLLSRIHATPRQQYGPFLADVQAGIQKEIEVIGELQEIASKHPYYKYNQKWNRQVQNAIFTVLLAGWLGGLTSDGKPGPIARLLTLEEVGEIFKVPVNLKDRDAFHLTIEEYLLALTDLTSELSRLATNAVTLADFSMPVEISSFVKDLFAGFQLLNLKNDILRKRVDAVKYDVKRVEDVVYDLSLRNLIPQKKEAAAVEPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC09</accession>
    <name>A0AAD8XC09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361717.1">
        <property type="nucleotide sequence ID" value="XM_060508902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC09"/>
    <dbReference type="GeneID" id="85392801"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018852">
        <property type="entry name" value="DUF2456"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28297">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28297:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10445">
        <property type="entry name" value="DUF2456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="19849" checksum="C92F301D363F0E80" modified="2024-05-29" version="1">MYSTQNIARNPIRLFQLPNTLAGDAVVTMIIQTTMTWFIELFLANRDMKNGSVRPIGFIEEPSSPFMRWFMMLNLEDTRHTKSRLSVFAEHLIRIGLIFVVSFFLLWPASVGILTVIGTRGSGNDWDWYFQSKWAPEAFKGILGGLLALLTTPAMASFWLVKEGWSLKRGGTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC20</accession>
    <name>A0AAD8XC20_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_757310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000159">
        <property type="protein sequence ID" value="KAK1711540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359093.1">
        <property type="nucleotide sequence ID" value="XM_060514876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC20"/>
    <dbReference type="GeneID" id="85398774"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10023" checksum="438180E66579AE1A" modified="2024-05-29" version="1">MSSEAPTGDVQDNEYVSRQGDREPIGVLGDDAKVEDPIDAETADSDAQLERDDKEAIDKSNIVEERTRGAKPTGEYREPGDTEGLEDKRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCG1</accession>
    <name>A0AAD8XCG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654962</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361256.1">
        <property type="nucleotide sequence ID" value="XM_060510766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCG1"/>
    <dbReference type="GeneID" id="85394665"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="15743" checksum="3D2D299793B8DF6D" modified="2024-05-29" version="1">MAQCTFALLRRIIIDASVKWHGPQIPFASSNAGDKVIKAEEKPELGLSDGLWHEAGAKDGSGLSADGGDEEVISKQERLAVRLVRPDDWGRTTGYAIVVNGTPWEEYSEAGSRFGTTTPSVGWESVSVPVSLLTILSEKAFEKLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCT6</accession>
    <name>A0AAD8XCT6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_583007</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362512.1">
        <property type="nucleotide sequence ID" value="XM_060505609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCT6"/>
    <dbReference type="GeneID" id="85389508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="15"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="252" mass="27418" checksum="6C1D2F8595A6F923" modified="2024-05-29" version="1">MPTEGVYYTPNGKKTVIPLENNPDVFTSLIHDLGISPELGFFDVYSLDEPSLLSLVPRPALALIFISPAPMYYAVRAADGTKLAKEDGVTYAGCGPEEPVIWFRQTIGNACGLYALIHAVGNGPAREFVQEGSLIDGLLKEAEPLKWEKRADVLYNSQPLEEAHMKAARRGDTAAPPAEEKPGYHFIAFVKGKDGHLWELEGGSDGPVDRGVLGEDEDMLSEGALERGVKRFIGFADGNLEFSIVALAKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD76</accession>
    <name>A0AAD8XD76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mannan endo-1,4-beta-mannosidase A</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Endo-beta-1,4-mannanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_630545</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362006.1">
        <property type="nucleotide sequence ID" value="XM_060508841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD76"/>
    <dbReference type="GeneID" id="85392740"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF21">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165813" description="Mannan endo-1,4-beta-mannosidase A" evidence="11">
        <location>
            <begin position="22"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="12">
        <location>
            <begin position="27"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1721210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="44722" checksum="7492F7A4BEC29C6F" modified="2024-05-29" version="1">MLPQLSGLLSIGLLASGAASAACIRKGFVTVKGTKFQLDGEDFNFAGSNAYYFPFDNNQADVEAGLTAAKDAGLKVFRTWGFNDKNVTYNAGGLPQYGGEGAGDTDIVFQRWENGTSVINIEAFDKVVNAADKVGIKLIVALTNNWADYGGMDVYTVNLGGKYHDDFYHVPAIKDAFKRYVKEMVTRYKDSPAIMAWELANEPRCGADGTRNLPRSDDCTPERLGAWITEMSAYVKSLDNKHLVTWGGEGGFNIESDDWAYNGADGSDFDHELALPNIDFGTFHSYPDWWSKTVEWTEQWIRDHAASGKKVGKPVVHEEYGWLTADKRLEYLGKVDDTPRTEVLGKWQAISLEEEMPDMYWQYGFSNYSYGRNHNDGFTIYLDDAEAQPLVYEHAAKVNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDE4</accession>
    <name>A0AAD8XDE4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_583708</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362216.1">
        <property type="nucleotide sequence ID" value="XM_060505689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDE4"/>
    <dbReference type="GeneID" id="85389588"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000021">
        <property type="entry name" value="SFC1p Mitochondrial succinate-fumarate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="115"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="219"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1721420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="34849" checksum="58BEA5CE167CDD92" modified="2024-05-29" version="1">MASKTKQDGKAPTSAAVNLIAGGGAGMMEALACHPLDTIKVRMQLSRRARQPGAPKRGFIKTGVEIVKKETPLGLYKGLGAVLTGIVPKMAIRFTSFEGYKNALADKSTGVVSGQATFLAGLAAGVTEAVAVVTPMEVIKIRLQAQHHSMADPLDIPKYRNAAHALYTVVKEEGFGALYRGVSLTALRQGSNQAVNFTAYSYFKEALKKYQPEFEKTTLPGYQTTLIGLISGAMGPLSNAPIDTIKTRLQKTPAEYGVSAWSRITKISADMFKQEGFHAFYKGITPRIMRVAPGQAVTFTVYEFLKEKLEKSNLAFSGAGYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDP2</accession>
    <name>A0AAD8XDP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein trafficking Pga2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_586418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360953.1">
        <property type="nucleotide sequence ID" value="XM_060505946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDP2"/>
    <dbReference type="GeneID" id="85389845"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011431">
        <property type="entry name" value="Trafficking_Pga2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28199:SF1">
        <property type="entry name" value="PROCESSING OF GAS1 AND ALP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07543">
        <property type="entry name" value="PGA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022909">
        <property type="entry name" value="UCP022909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="149" mass="16915" checksum="C971E0F06D18DDAA" modified="2024-05-29" version="1">MSAVVNLLNTIWTRFSTNLRGTLEGMSAEKWIRLVIIVGAYCLLRPYLMKLAGSSQMKQHETKPEDEFDGPKAKVQPNTLRGQVDIPEDSDDEGTSQATGATTSTDWGKKARKRQRDVLKKMIDAEEKRLAELQEDDEDKDIEEFLVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDW5</accession>
    <name>A0AAD8XDW5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_582480</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362771.1">
        <property type="nucleotide sequence ID" value="XM_060505557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDW5"/>
    <dbReference type="GeneID" id="85389456"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="57564" checksum="3FC2411D63613973" modified="2024-05-29" version="1">MGTQPLAHIALLTLSSWLLFYLARGIHQAYFSRLSHVPGPKLWTILPFIPKFKILFGTIDQDIREFHRKYGNVVRYSPDAVTFTTSQAWKTIYGHGHGQFPKYSASKQLDPDSNILDADDVNHARIRRGVAHAFSPRSLAEQEPIIHDYVDKLVRRLSDVAESRMPTEMGRWFHIASFDIIGDLTFGESLGGLDNNEFHHVVTSVLMFIERARKLFELNTLLGPLSWIVLPILARDVQNGFMDQFDYTRKAVNKRLDNDSEMTRKDFMQGLLRGRDEKTINSTEEIVTNSNTLFVAGSDTTATLMTACTFYLLSTPHAHRRAVEEVRAAFKSPGEINFTDATARLPYLLAVLNETFRLYPPVPTSLERIVPDTKEPTYIEGVFFPPGTRVGVHHSAAGLSASNFAEPESFAPERWLPSVVQDTTSPFHADKRDAIQPFSYGPRNCIGKHLAYNEMRVIIARLLWEFDMRLDASSSEWTQPYSKHKAWAIWKKPPLVVHIKRRPLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK3</accession>
    <name>A0AAD8XFK3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Pectinesterase</fullName>
            <ecNumber evidence="4 11">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_584841</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in maceration and soft-rotting of plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="4 11"/>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361735.1">
        <property type="nucleotide sequence ID" value="XM_060505801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK3"/>
    <dbReference type="GeneID" id="85389700"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000014">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF127">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041766078" description="Pectinesterase" evidence="11">
        <location>
            <begin position="17"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="12">
        <location>
            <begin position="30"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1720224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="34754" checksum="F84B0BB2AE3C0977" modified="2024-05-29" version="1">MKSFLTALTFVTAALAASRTSAPSGCLTVKKSGGQYSTIQKAVDALSTTDSAKQCIFIDQGTYSEQVLVPARTAQLTIYGYTADTSSYAGNKVTITAKKSQADGLNNDASATLRIKAKNFKLYNVNVANTYGKGSQAVALSAYSDSAFYASAFTGFQDTLLAQQGNQLYSKCLIQGATDFIFGQKAMAWFEKCDLRVVAASLGYVTANGRASSSDKSEYVFNSCSIAAASGNTVADGAYYLGRPWGQYAQVVFQKTSMTGVINSAGWKQWNDGDPRTANVLFGEYQNTGIGSQGTRASFSKKLSAAVTPASILGSSYTSAAYYDSAYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFS0</accession>
    <name>A0AAD8XFS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_288483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365767.1">
        <property type="nucleotide sequence ID" value="XM_060502174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFS0"/>
    <dbReference type="GeneID" id="85386073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057082">
        <property type="entry name" value="PH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057081">
        <property type="entry name" value="PH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23076">
        <property type="entry name" value="PH_FT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23074">
        <property type="entry name" value="PH_FT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="231"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="352"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="483" mass="56202" checksum="4A30A28F756B4BD4" modified="2024-05-29" version="1">MEQGIQRIDYRLLQGCCLEAERADIISVSLEGLRMALPEAYGGTITSLVDEIRRSARKLRDLADLSQMHFTRVPILLNYLDVILPCYCKTLRDITEFYEDRTVSKDMRWRRMYHKMTQEAGGLPLPQRFMLYNCFLESLRHLLMRSTLFDLNGLETLRTRIIKLREARGLPTPTTQVGPVLRPEIMLRPTPQDPTLHWAEQIFSLPLTSRTALKHIRPSTAYGPFQTWGQLNIPKQVKMLFRRPFDEDRLALMTYLNHVNQTPYFLLRTYHLGGQWFSLLGAHELCIRREGSALLLDRYSHSQMGLKLWASLYFKTWEELVLFHCTFVSLKARIILTSRMSPREFKLGSESRLFQAQILDDGFKHSLIVYRDLVTQGLRLQASVWDGELKNCPVWTAFVTHQSASPTWLVRKSDHRIWLKDVQLYVFCQQYHQQNQRKGSSAGAFEIDFVSEMGATRFIEEIQSQVDPSEASTDTMEAIEDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG41</accession>
    <name>A0AAD8XG41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_256865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366714.1">
        <property type="nucleotide sequence ID" value="XM_060501971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG41"/>
    <dbReference type="GeneID" id="85385870"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="29656" checksum="61E4A6CD66F9CF2D" modified="2024-05-29" version="1">MSLPSRILIFFNQQIVTLDVSLQRFRNQRDRIDREPPSVEHRSHPVEFAPGLTEHRRPPTGTSNYPPRTTESSGSAPVTLPPSAIKTPIGCKKRAGVFKVKRTVVPPNPVVQRRNEIRDVIEPLFSDAPFVLICEGKERDAVISTIRLTDALDPVDVWAKLSGVARQCTRRWKRLLGPVRLELVNLIIIGRHAQRPGAFRGQFQIVNIAERIEALQKLISNYNYDITEPSNPDERRHDSRGMGRRLQISQTQQLRRPNSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGR2</accession>
    <name>A0AAD8XGR2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_774107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366682.1">
        <property type="nucleotide sequence ID" value="XM_060515413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGR2"/>
    <dbReference type="GeneID" id="85399311"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="499" mass="56125" checksum="A16CD80B1C44068F" modified="2024-05-29" version="1">MAIISEVVAFVSAHLPFLIAAILAIHFVRNFTARGVSKIPGPFLAKISDIWRFVDVARGRAHETHIKLHAQYGQYVRLGPNLVSIQNLDALKTIYGVNKGYRKTEFYAVQQQLANGKPTQTLFTTLDEDFHAKIKRPISSLYSMSTLTEFEPFVDSTIEKLLEKLDEFAGAGRELDLATWLQYYAFDVIGELTFGKPLGFLDQGQDVGDVMLSLEKMVDYAGMIGQIPWLDHLFIKNPIKRKFGGGSTGAVAQFARQCLEERLHRAEGKIENPSHRDFLTRFLETKKTHPQVVDDRQVFSWTLSNVNAGSDTTAISLRAVLYYLLKNPWTLTKVMKEIVGARKNGKLSIPVTWKESQELPYLDAAIKEALRLHPAVGLLLERIVPKAGVQLPDGPFLPEGTVVGINPWVMHRHPAFGDHLESYVPDRWLQGEHEPLESYEIRKAEMQGATFTFGAGPRTCIGKNISLLEIYKAIPTLLYTYNVRNAPKLVKIRLTVAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH73</accession>
    <name>A0AAD8XH73_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367177.1">
        <property type="nucleotide sequence ID" value="XM_060513909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH73"/>
    <dbReference type="GeneID" id="85397807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042051549" evidence="1">
        <location>
            <begin position="20"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="122" mass="13008" checksum="9DB08FCF2BBCA88C" modified="2024-05-29" version="1">MQFPIIIATAAALFLGAEAGAVPRQDPHITDFRIWSEQGCGAAGNLGVWTITKSQTDVCQTTFNAPDNVVKAIRLSSLTEGCEMTAYPTADCGEGGRQVGVQTCEEWSDVADNFLSFKVTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHH0</accession>
    <name>A0AAD8XHH0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_542718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368229.1">
        <property type="nucleotide sequence ID" value="XM_060503411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHH0"/>
    <dbReference type="GeneID" id="85387310"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="44713" checksum="93AE7429CF1F585C" modified="2024-05-29" version="1" fragment="single">GKLDGLEGLPLEIIFDIYHQLDICSIFSLAQVNTLFHGLLKRNMAAILLPVLQREFSPLPELLQVFTASDQDMVQYGDTFQPRRVVFRRFPGDMTGVTLSRGGVQHNAGALNGDKPPRTTLPSPRSVTLVERDLRPLLKYCLVTRQWEELFPQLHWFATPEDCRQLDELEKFKLRRALYRWWLYAFYFHGELLRPRSSQPEPFVNDVRTSHMRLHSTHELIEMRDLFLSMKNLVRHYIYPNLEQNLDPVDESSPLETMIETSIRERIVDTYAKLDPEDLMFYFENLFNYPRKRLVMDVNLKHPAFSQDQESFVAAIQSAADERPWLFDIADLTTIGGIVTSDDDLNEHLGRDGSHDGSIPPPGAFRRPRGIWAPPGDDGRALAERSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHK5</accession>
    <name>A0AAD8XHK5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_139791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368364.1">
        <property type="nucleotide sequence ID" value="XM_060501277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHK5"/>
    <dbReference type="GeneID" id="85385176"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="22422" checksum="7EDCDFCE84A9C376" modified="2024-05-29" version="1">MPDQKSRDSEEFLPNDEIARFVNKDQVEKVLRFANLGTDTSLIDFVSDDANQLFLILVSMSSKDEEQVSFLEALKAHLFTNKSLPITFQGARNAVGDKVFWWQPYSPSGGDCPRLPLHIQRCGRIQKDLFQINQWRFIAPVFGTGQDFRFHFRKSVVLPYLEVKQRVESRGFFGEVLQVIVHAAHINAPNLIKTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHX1</accession>
    <name>A0AAD8XHX1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_579707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364000.1">
        <property type="nucleotide sequence ID" value="XM_060505273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHX1"/>
    <dbReference type="GeneID" id="85389172"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="54" mass="5988" checksum="89CD61A9DC5EA691" modified="2024-05-29" version="1">MCDFTKNYYIYTSCIDPGAHFFRTSVDGNRSRACGSGPHERYIVVPGHCPLCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHY2</accession>
    <name>A0AAD8XHY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_573334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367076.1">
        <property type="nucleotide sequence ID" value="XM_060504606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHY2"/>
    <dbReference type="GeneID" id="85388505"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056599">
        <property type="entry name" value="AAA_lid_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054289">
        <property type="entry name" value="DUF7025"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF3">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23232">
        <property type="entry name" value="AAA_lid_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22942">
        <property type="entry name" value="DUF7025"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="649"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="902"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="958"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="997" mass="113313" checksum="B3F9D33D12807179" modified="2024-05-29" version="1">MSESICGFESENVDPTSQKADTPSSEQGGHLPAEQEELPPEDTLKEEEGEVMRAVHRAAFPDAIEVRHVFEEEKESGRMRMRYHQASLHHTFTNLRIEDLERGLKELKAAFENRDDTWEAPKKTKFPIHRHELRRSYANQFRITRLTAILHCAQQPALEVQVTERTPSTLLTSENESQSLSHQTIENDEGVSLKSSSLKTPERLRIRSWSLLSHLEKITGRAIMGLAQSTMIDGIKVHSGVAFLRPFKFFAEHHDVIKKSQAEMEAWIHTGTPKHRRRSHEQANESIRESSTQHDFDDKNLVEDLKLLVRFLDNDLKSTFDLRQKVKDGTALEIEYDDLWHLFARGDIVITTSDPNQAYRVINMAGGREPLQYEARYPRSDVEKPVPVDGFVLDCLSFGSDGTAYIPKLQRLPIHRFHGKRLITSLPVYPLRFDPKHNVLRAEFEAMGTRFLDLTRETSCHKLARGKTLDEPSHDLDNQVIVDMRLAMTAKAEWRMKTSISSEELTRRDKRETIEGSWCYHREPGCCGGDVIFNDLVYDEENAAAFGQKLTRMLGPLQGKDLTQEDLMLMQPYVYAFVLRSRQWATIWTTDLKEVVFENNFNDLVISENHKETVRALVRTHENKRAAEASPGVARSVGTALDLVKGKGAGLVILFHGPPGVGKTSTAECVADDTHRPLFPITCGDIGETAAEVETNLQYSFKLAHKWGCVLLLDEADIFLAKRVRDNIRHNAVMSVFLRTLEYYAGILFLTSNRVGAIDPAFKSRIQMSLSYNDLDLLVTLKIYEKFIKRAKEEQHSTGTQNFKIKEKEIMSFAEKHYNRLELEGRYTWNGRQIRNAFQTAIALVEYQYISKEADEPKPSLGKKQFKKVAKGFKEFDNYLINVNGATEADDARRDGWRHDIRKTVSSPMPYKSTQAGRIQQGSKHPARNLESEDSSETGNESDEDSENDTKDGRASEKNATPSTVAGQSLAAAGASVDMEQYQQFLKFQKMMSGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR6</accession>
    <name>A0AAD8XIR6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Core protein II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_610587</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368246.1">
        <property type="nucleotide sequence ID" value="XM_060507599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIR6"/>
    <dbReference type="GeneID" id="85391498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000021">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="12">
        <location>
            <begin position="49"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="203"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1728191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="47307" checksum="1508E41E101F8B59" modified="2024-05-29" version="1">MISRPSLTRAAQQTLRNSSCARTISGRRFASAAAGSGAFETADVGGVKVAARDSQGPTTKLAIVAKAGTRYQPLPGLAAGLESFAFKNTTKRSGLRIVRESELLGSQLTAYHTREALVLEASFFRDDLPYFTELLAEVVSQTKYTTHEFHEEVQPVLRLKQSGTSAAALALDSAHSVAFHSGLGSPSNLTPSIPIQPYLSEYAVSDFAQAAFAKSNIALVADGASAANVSKWAEQFFKSFPSASSGKLALNTAATKYFGGEQRTYSPSGNAYVIAFPGATTGQASPELAVLAALLGGKSNIKWSTGFSLINKAVGVVPGLSTSTVNLSYSDAGLLTIQLAGSASAVRGAAQETAKALKSIAEGTVSKEDLTKAIAKAKFDALEASEKRSGSILLAGSSLVHSGKAVDATEAIKSIESVTAEKLKAATKTILEGKASVAAVGDLFALPYAEELGLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJM1</accession>
    <name>A0AAD8XJM1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_750418</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366970.1">
        <property type="nucleotide sequence ID" value="XM_060513912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJM1"/>
    <dbReference type="GeneID" id="85397810"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="150"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="61365" checksum="6FBC9A8DC36FC55E" modified="2024-05-29" version="1">MVRTTAARTYGKTSTKAKARRLFAELPQTPIRKPNATVTLDSEDDSIIKITEDLDALGINLDSYSSEDELSKDFSEVVVESPPTPQKPETPPRAVKQTPRTAKTTRRIAKGTLLTPVSRAETPKTKAPEVPVEPQPEYRILTWEDVCPPGDTIEKIAEASYAEVYRVRNDRGTSIIKCIRLESPIKAQTKAQERSGLVDEEPHSEDDMRGELSISEWLADIPGFVIYKERYLVKGKAPKCLLETHQSFHRKMKRKDPDRLQFYPSPSRYLDETTFLVVELGDAGIALEDFELTDSGQLWDIFFHVAIALARAEDLACFEHRDLHEGNLCIRRSEDPQTRNPKKAGPYFGYSGLDITILDYGLSRAEDLELEESEPIALDLEKDLSIFTSTHAPQCKVYRQMRSFLMRGERGHLPPSAHKSPYCKGVDGEPLSWDVFVPYTNVLWLAYLYQYMIKGFQGDKKDLAAFKKVTKELWKYLDPDAKAGTPAFGTSAEVVRFAVEAGWIDESQLMGDIEEDREESIILSREEVQELGLRRSPRKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJP0</accession>
    <name>A0AAD8XJP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_554074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368678.1">
        <property type="nucleotide sequence ID" value="XM_060503508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJP0"/>
    <dbReference type="GeneID" id="85387407"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="47823" checksum="5F81445239DEE1A8" modified="2024-05-29" version="1" fragment="single">DGDNNSVLEGTAIEYRTYKRRWFGLAQLTLLNIIVSWDWLTFAPVASNAATYYRVSESAINWLSTAFLFAFVAIFPLTIRILHMGPKPSFITAAALILVGNWIRFAGSHSRSPTGGNYGVVMFGQILTGLAQPFVLAAPTRYSDLWFTNRGRVAATALTSLANPLGAALGQLIVPFWVVDPQDMSPGVLYVAIISTVASLPAFFIPAAPPTPVAPSSRTLKLGIRDSLSIVSRSLELWLILLPYAFYVGFFNSISSLLNQMMGPYGFTDEEAGIAGALLIVVGLVASAITSPILDRTKKFIPAIKVAVPVIGLCYLVFIWMPETRNIAGPYVVLAVLGAASFSLVPVALELLIELSHPVSPEVTSTIAWAGGQLLGAIFIIISDALQADDKANPPKNMKNALIFQAVVALVIVPLPLCLGLFGRSDRVSLRRVRSDEASTRQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK00</accession>
    <name>A0AAD8XK00_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_608373</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368590.1">
        <property type="nucleotide sequence ID" value="XM_060507476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK00"/>
    <dbReference type="GeneID" id="85391375"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1170:FF:000001">
        <property type="entry name" value="Endo-1,3-beta-glucanase Engl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="9">
        <location>
            <begin position="236"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="10">
        <location>
            <begin position="564"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="922" mass="98949" checksum="81D349418C11D138" modified="2024-05-29" version="1">MLPHAELRNFSPCHALPNITPKARNRLEHPLQPHTNTIRSLHSPAMAGFHKKMGILRLTLIQVLLCENALALFHQQHVRLHDTHPDSVSLGQLNVRALLLDSRDIACLTETANVTVTVRATKGSQQTSAPVLDNSQVADVVTSAEASGTVVILPSLTNTAPQTSGYVATGLTASGKVTSCPLMSNPIPTPSSLIDTAAPATSVAPLPSAPMPSGDIFSEPIGTGAPPGTISARSDHPVPRKGITSTSPLQTNKFYSNFFLGDQTAPTYTYPYGIAWGAGRGAAASYGMTISHIEASQRVFGPTKADSGAASYFINPVGIQSMVISAQELGSDTAVGIDSVTAFSATIHLKPNAQAVPAVSFPLVQGMPFITAQYAGATPVIRTGVFFRTVTRVTQDPKAGVAKYTFQLEDGKIWRLYAYATTGSQLNLQVVNNGLAQSTQPFYGIIQVAKDPGNGEALLDQAAGVYPTTVALSGSVSGTTGSCTFKFAKDGHPDGKLVMYALPHHVSSFDSTTRNGVQPVQLMTPAKGIATAVLADQWTMQESNLPVGMGFAPWSPDKGSLTTLSDNAKVVIRGIAAQEVSQDMMAQSDLDSMYFSGKALAKFAILIIVINDILGDPALAQSGLNRLKAAFATFATNKQKYPLVYESAWGGVVSSATYVTGNDGADFGNTQYNDHHFHYGYHILAAAAIAHLDPSWLSANKDYVNALVRDVANPSTQDTYFPTWRAFDWYHGHSWAHGLYASYDGKDQESSSEDMMHAYALKMWGDASGDSMLSSRSNLQLSIIARALQDYYLYKSDNVVQPPQFIGNKVAGILFENKIDHTTYFGANIEFIQGIHMIPLLAPSPFVRTPAFVKEEWDVYFSNGRVDTIAGGWRGIIYGNLATIDGKTAWNFFNSSNFDPSWIDGGASLTWYLTYAALMGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK37</accession>
    <name>A0AAD8XK37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_608351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368891.1">
        <property type="nucleotide sequence ID" value="XM_060507474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK37"/>
    <dbReference type="GeneID" id="85391373"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041941028" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11716" checksum="866EC4C278926792" modified="2024-05-29" version="1">MLLLLLLQLELAGREVDLLLLRLLLRLVVGAEDGVEGEVVGVGGRKVHGPWCFCPLSRGGVWVGLHNWRAAVVSEMVALLSCSLRFSVLPGERSDSAGARRCQKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKQ3</accession>
    <name>A0AAD8XKQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_606992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369226.1">
        <property type="nucleotide sequence ID" value="XM_060507404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKQ3"/>
    <dbReference type="GeneID" id="85391303"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="137" mass="14326" checksum="23224411948CB3F3" modified="2024-05-29" version="1">MAQLNMFSRLSKTDSNKPLIDNDSASESQTSSSPKKSLYRKFQDSKRGEISDADVLKYTGMSKDTLNGWAADRPGVGGNRAAGSITTGSPSGLGGMMAETGYGGWGTDSNSTPKLPPTTKSENQESNDAVAGVVAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKR0</accession>
    <name>A0AAD8XKR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_68996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369193.1">
        <property type="nucleotide sequence ID" value="XM_060511300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKR0"/>
    <dbReference type="GeneID" id="85395199"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="220" mass="23609" checksum="E8F8AE6B0E64619E" modified="2024-05-29" version="1">MCRRSGELQETRVGASAKASRYHIHRVFQVRSSSSCHQCRFGPGGQSASQAEGGCASIGSTCIETLTVACFIIAAASVDVPGIVALWHSRGSVGIRIRTLQLAPASIYSAKKESSAEMSVLLIMLGRKFLKPGILDGARALGTHRRGTWLERWRGCWRGTCKGGSECGGGKCGMAPAKLSHLQMKVDSVSLFVKDARVKPRLDRPFRSDMGSMCPALVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH4</accession>
    <name>A0AAD8XLH4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369549.1">
        <property type="nucleotide sequence ID" value="XM_060504074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH4"/>
    <dbReference type="GeneID" id="85387973"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="428" mass="48389" checksum="F620BF64EC55F8DA" modified="2024-05-29" version="1" fragment="single">SAIKSKIEIAMPNKNKEQQSPTQKRRAELIAQANEIRQKQGAGKNARTSKLDQIKRLDEQMRSRINEQKTARSKVNFKSVEEVDRQIEKLDSEVNSGRMKIVDEKKALAEISSLRKLKKNFSQFDDSQKSIDDLKAKIKEIKDSMEDPEAKAMSEQYNKIQAELDAIKAEGDEAYKNLSSLRDERTRLHNLQNEKYAALKTIKDEYWQQRKAAQAHEREAREKARERRKNEAERYQKERKKADAEKFLADASDPAYLEEIRRANSLLQFLDPTHKVEKAPLQAASGLTAQASRTVDDSGIKGMKVVSKKDRDEDFFPAVKKGKKGKKGGAAEDKAGKFNCPPSVVEDCAFMGIDPPMAASDVPAVAEKVKAKLDHWKSDQEAQTQRNIEKAKKQLEKLEADEANGVSNGDSVEEVTKDLKETSVEEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLQ0</accession>
    <name>A0AAD8XLQ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_748107</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369773.1">
        <property type="nucleotide sequence ID" value="XM_060513564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLQ0"/>
    <dbReference type="GeneID" id="85397462"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1729718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="161" mass="17237" checksum="3025129EB708FBB9" modified="2024-05-29" version="1">MNSFRFARAALRARPAAFRAPLQRRTYADAIKLSLSLPHQSIYQSQDVVQVNIPADSGEMGVLANHVPAIEQLKPGLVEVVEESGPSKQFFLSGGFAVVQPNSVLSINATEGYPIEDFSAEAVKSQLAEAQKVASGSGSELEIAEAKIEVEVLESLQAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM54</accession>
    <name>A0AAD8XM54_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_448021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369946.1">
        <property type="nucleotide sequence ID" value="XM_060503151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM54"/>
    <dbReference type="GeneID" id="85387050"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="87" mass="9816" checksum="BB0FBC58C3070354" modified="2024-05-29" version="1">MKSALATVPCLRIMSCSWHQSPLYLVHYPRLTRAACLDASYEALGIHTISQGYLSLDVATHYAQLTPRPVVTRSDLHEIQRVVQPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMQ4</accession>
    <name>A0AAD8XMQ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_400792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370347.1">
        <property type="nucleotide sequence ID" value="XM_060502839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMQ4"/>
    <dbReference type="GeneID" id="85386738"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="213" mass="21828" checksum="1B26D50CD562DC98" modified="2024-05-29" version="1">MADRTSRAAPPPPGAPRRAVRRNLFQGLTRRATGTTTTGTTGQPMASTAGAGSVSTTAAAAAAAAAATMGGVGPGGSSSTGAAGHGNGNGHVGGGETLRLEVDVLSDGGPPSAMGPAEIVVRDEHGEIEIGDLPTLVFDEADEAAAMDDREESKKERQRLAEAVKQHQVNHTAVREQPEELLEAVKASLRAKVSALADDNWMFEAEPELPRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMQ8</accession>
    <name>A0AAD8XMQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_566694</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370313.1">
        <property type="nucleotide sequence ID" value="XM_060503877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMQ8"/>
    <dbReference type="GeneID" id="85387776"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="416"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="680" mass="75198" checksum="7B7A1C7238B39A50" modified="2024-05-29" version="1">MEKITDKIAALPADANYFSLEFFPPKTAMGLSNLRDRLDRMERALRPLFVNVTWGAGGSTSTKSLELAEICQRELGLTTCLHLTCTNMSRKLIDKALEDAKALGIRNILALRGDPPRKNEYRDTEDSETDDAEDFVWAVDLVKYIRKNYGDYFCIGVAAYPEGHADESHPQGQSFEHDLPYLVDKVQAGADFIMTQLFFDIKAYENFEKVLKEHPSGAFKNIILLPGLMPIQSYQMIKRTTKLSHAKIPDNLMARLDAAKGDDEKVKQVGVDILSELVEQVKEVKSRTPGPKGFHFYTLNLEKAVSFILERTGLIPDPKIEDEEAIIDDGPGIPVPVAVPAVQLNGLSPVPHPATRTLSNGRRPSSMGSDPHNRIIVSGSASNPAYETTTAGLMVSEPVNTRANTLAISEGVGAVGREATWDDFPNGRWGDARSPAYGEIDGYGVSLHMSVTQAMRLWGTPKTVQDINNLFIRHIKGQLAAIPWSEEELLPESNIIQQELLDLNTRGWWTVASQPAVNGIPSRDLTFGWGPQHGFVFQKAFVELFIPSSDWAGLVARLNEVTDNTICFYAANGAGDFVSSDASGGLVLEGTEASTNAVTWGVFPGKEIITPTIIEEVSFRAWAEEAFKIWGEWAKVYGKGSESEALLERIGSEYWLVNIIHHDYVERDALWKLLSGEKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMZ1</accession>
    <name>A0AAD8XMZ1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="4">2.6.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-aminobenzoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">p-aminobenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_602304</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11672"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58406"/>
            <dbReference type="EC" id="2.6.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370364.1">
        <property type="nucleotide sequence ID" value="XM_060507161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMZ1"/>
    <dbReference type="GeneID" id="85391060"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008153">
        <property type="term" value="P:4-aminobenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010117">
        <property type="entry name" value="PabB_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01823">
        <property type="entry name" value="PabB-fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF18">
        <property type="entry name" value="AMINODEOXYCHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="13">
        <location>
            <begin position="324"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="12">
        <location>
            <begin position="582"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="555"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1730309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="842" mass="93298" checksum="A5699319BFD97D65" modified="2024-05-29" version="1">MTRPQILFLDAYDSFTNNIVSLLTTLLDADVHVLPIDTPLLDQKSPTFSVDFHRELSRYHAVVCGPGPGSPENETDVGLMRCIWRLQDEHMLPVLGICLGFQSLVLSSGGKVRRLQRGLHGMVRTIQHEKPEATCAEDIFNGVSEFKATLYHSLCADIGQDSISNSIWAESRWRTQKTAPELLPLAWVDEERDIGRERILMAVKHQSKPFWGLQYHPESVCTQPAGHAVISNWLREAMAWNLKANRTVLTGERFLARNAVKPSLLCENRAAAQRGNAPILEWTEMPTPLATVGLDCEYRYKTISLPANVKVPDIVEILKSGRTEHIILDSSNSSNMATGAADVRGRFSVVALDVEESLRIEHHVGDDFATARIPSIQGLPVDLVETVPFGPQKNIWHLLSGFLEKRRIPALGELQTPFRGGFMGYLTYEMGLKGIDVALAANRGHQRPDLCFAWVTKSIVVDHVKGLLHVQHLQKRKLNADFWIDSVVASLQTSHFWQSPGKATVNGSDASTVSTRPVIRVPAADEYEAKVSRCQDFIAAGESYELCLTDQTTITLPGRPTRDHQNGLTNRHPSSPEQRQKKSSHVAPWRLYKTLRARQPAPFGSFIRLGGATLISSSPERFLEYDADGFCSMRPMKGTVRKSNQVATLAQAEAILHVPKEEAENLMIVDLVRHDLHGVCGSGNVTVPHLMKVEEYATVFQMITIVNGQLPKPKTMTTTGADRQHTGLDVLAASLPPGSMTGAPKKRSCELLQEIEERRERSLYSGVVGYMDVTGKGDWSVTIRTMFKWDDEAAPPEEGETEPREVWHIGAGGAVTILSTAEGEREEMFTKLAGPLGVFAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP80</accession>
    <name>A0AAD8XP80_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_601077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370963.1">
        <property type="nucleotide sequence ID" value="XM_060507076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP80"/>
    <dbReference type="GeneID" id="85390975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="69" mass="7557" checksum="83490EEEB64502B0" modified="2024-05-29" version="1">MHRPLRSEATVDQKSSQACTTHASLFPSEQKIRGGRSDPRVSRNIRRTLKIPSREASALPQSNAGPACN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPK7</accession>
    <name>A0AAD8XPK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_715178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371382.1">
        <property type="nucleotide sequence ID" value="XM_060511720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPK7"/>
    <dbReference type="GeneID" id="85395618"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="81"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="46053" checksum="A634E8D7269AF9BC" modified="2024-05-29" version="1">MDPRSEDGGNGPSNTAAQPPPLRRRLSMEEDYFYQEVMTSPFRRPSQPPPYERDARPKRLVAPRVNSQHGVGEDLPGYSCDIELEGVWVKKMEIENTTKRAEDRNWHTTIVQLRGTALNFYNVKKDWGWGRTRDGPTISPDNPPWVRKASLDRAYSLQHADIGIAADYKKRRYVIRVRAEEDQFLLSCIELSTMVRWLEALFAAIDVAAPIDDRDYPRDQSIPRIQRIRWFRGQTPAPTNNYPVPTPRPLSPELRRVASAEAPDPFPASSTIEGLVHQAVVNERGETNVLDSESIYGPGPGRNELISSRLSTTSYPNEAIDPDTGKWAPEHQWSAAHDLLYAKLCYSVLLFKSPRKSNYIISKGKRWFVDWATGRMVRVLPPAYGEIDFFGPWQVIHTENRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQD0</accession>
    <name>A0AAD8XQD0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_714701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371708.1">
        <property type="nucleotide sequence ID" value="XM_060511664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQD0"/>
    <dbReference type="GeneID" id="85395562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30572" checksum="182F17D702243E0A" modified="2024-05-29" version="1">MPGRLEGKNIIITGATGGIGLESSSFMFREGASVLMTDLNQELLDKALKRVRDVVANVPGHLETLVVDVSSESEVDRLWGGLDVIFSNAGIMHPHDGDAHECSAEIWNKTFDINVKGVWYGSKHAMRSLRKHGKTKRSVINTASMVAIVGSATPQLAYTASKGAVMALTRELAIVHAREGEKSNVLMESLLNPMLQDFLGDDHAKRFRREVHFPTDRFGEAIEQAQAVVFLASEESSFVNAHGIVVDGELIKAYVTLEGPATEAPRNLGVWFFTLSTPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D178</accession>
    <name>A0AAD9D178_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Beta-galactosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_568056</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369666.1">
        <property type="nucleotide sequence ID" value="XM_060504021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D178"/>
    <dbReference type="GeneID" id="85387920"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000065">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996050" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="11">
        <location>
            <begin position="380"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="986" mass="108677" checksum="CB86629D9EA1E9C9" modified="2024-05-29" version="1">MRFHRALTALIWLFTSGAWATDNGLTDVVSWDKYSLVINDTRTYILSAEFHYQRTPVPELWPDILQKFKANGFNTVSIYFFWSYHSAAEGVYDFETAGKNIQRLFDYCKEAGLYVIARAGPYCNAETNGGGLALWGSDGRFGKIRTSDERYQAGWLPFITQVGKIIAANQITNGGPVILNQVENEYQESVYSPDHTSVIYMEQLKKAFHDAGIVVPLTHNEKGMRSRSWSTDYNNVGGAVNVYGLDSYPGALSCTDPTVGFNVVRTYFQWFSNYSFTQPSYLAEFEGGWFSNWGSPTFYDQCASEHDPAFADVYYKNNIGQRVTLLSIYMSYGGTNWGHSAAPQVYTSYDYSAPLRETREQWTKLFQTKLIGLFTRVSSDLLKVEMIGNGTGYGLSSSSAFSWVLRNPDTQAGFTVLQQASTKSMTPIQFDVTLNTTAGPVTVPNVVLNGRQSKILVTDYVFGKHTLLYASADIATYGIFDTEVLVFYLQESQTGEFAFKDAGDLTFEVFGDTDLQETTNGNHSAFTWKQVAGSTVVKFSNGALVYLLEQKSAWRFWAPPTTSNPTVKPDEQLFIQGPYLVRSASISHGVLHVSGDSDKATTIEAYVGNKPIETIDWNGLRLAATKTTYGSFTAQIPGAEDRAVTLPELSNWRAAEALPEAAPNYDDSRWTVCNKTTTPSPYAPITLPVLYSSDYGFYSGAKIYRGYFDGANATSVNITASGGLAFGWSVWVNGQFLGGDVGSASATTTNKTLTFPRSALVEKNNVVTVVVDYHGHDQASTAQGINNPRGILGAQLQPGSTRTNTGFKLWKLAGAAGGEANIDPVRGPMNEGGLYPERLGWHLPGFAPTGSSWKPESPLVGLSGAGIRFYVTDFTLNIDSDLDAPLGIEFSAPAGTAARVMFWINGYQYGKYVPHIGPQTRFPVPPGVLNNRGRNTLAVSLWAQTDAGAKLDGLKLVRYGQYQTDFKFNRDWSYLQPGWEDRQEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1Q0</accession>
    <name>A0AAD9D1Q0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-sulfurylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Sulfate adenylate transferase</fullName>
            <shortName evidence="9">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MET3</name>
        <name evidence="13" type="ORF">BDZ83DRAFT_426706</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically inhibited by 3'-phosphoadenosine 5'-phosphosulfate (PAPS).</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Homohexamer. Dimer of trimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The adenylyl-sulfate kinase (APS kinase) is non-functional. It is involved in allosteric regulation by PAPS. PAPS binding induces a large rotational rearrangement of domains lowering the substrate affinity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the APS kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1Q0"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010134">
        <property type="term" value="P:sulfate assimilation via adenylyl sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000003">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000802">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000052">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03106">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059117">
        <property type="entry name" value="APS_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027535">
        <property type="entry name" value="Sulf_adenylyltr_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050512">
        <property type="entry name" value="Sulf_AdTrans/APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004040">
        <property type="entry name" value="PRK05537.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42700:SF1">
        <property type="entry name" value="SULFATE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01583">
        <property type="entry name" value="APS_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="12">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="11">
        <location>
            <begin position="175"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="APS kinase" evidence="10">
        <location>
            <begin position="396"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric regulation domain; adenylyl-sulfate kinase-like" evidence="9">
        <location>
            <begin position="396"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="292"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="435"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="516"/>
        </location>
        <ligand>
            <name>3'-phosphoadenylyl sulfate</name>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="site" description="Induces change in substrate recognition on ATP binding" evidence="9">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00062002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="574" mass="63938" checksum="FD914364CFB006A2" modified="2024-05-29" version="1">MANSPHGGVLKDLFARDAPRQSELIAEADKLPSLLLTERHLCDLELILNGGFSPLEGFMTEKDYNGVVKDNRLADGALFSMPITLDVSQQQIDTLSIKPGARITLRDLRDDRNLAILTVEDVYKPDRVKEAIEVFGSDDDTHPGVKHLFNNTNDFYVGGKLEAIQRLAHYDFLDLRFTPAELRQHFEKLGWNKVVAFQTRNPMHRAHRELTVRAARSQQANVLIHPVVGMTKPGDIDHFTRVRVYKALLPRYPNGMAALALLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNKNGKDHYGPYDAQVAVQKYSDELGITMVEFQEMIYIPDRDEYQPANEIAPGTHTANISGTELRNRLKTGKEIPAWFSYPEVVKVLREQNPLPAQKGFTIFLTGLLNSGKDQIAKALQVTLNQGGGRSVSLLLGETVRHELSSELGFSREDRDKNVGRIAFVASELTRAGAAVIAAPIAPFDEARQKARELVEKAGPFFLVHVATPLEYAEKTDKRGIYQKARNGDIKGFTGVDDPYEAPAKADLVVNLEQQTVRSIVHQIVLLLESQGLLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2G6</accession>
    <name>A0AAD9D2G6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D123-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_646333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371432.1">
        <property type="nucleotide sequence ID" value="XM_060509953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2G6"/>
    <dbReference type="GeneID" id="85393852"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="435" mass="49052" checksum="BC9AC2785DC8547B" modified="2024-05-29" version="1">MPSLEGLTEGQPTLDAINNATAQETEELTFPPVTKEHILNCSYDSWFPKYRTVSIRSRIIKLSPDFVQYIRDDGIILADDDEPQEDEAEEEWSASSNTAGAPRRNQHLEEDDSDDEPEADCRPPNERFPEIHQEIKERIKELGGSVAPKLNWSAPKDAAWISPHQNTLKCTTPNDIYLLLKSSSFVSHDLEHAFEDTVPSSANRPFQPVLVLRPFFAPNPALEFRCFVKHRTLIGLCQRDWNYYPFLGGLRPALVSKITDFFEDRLRFTFPDGSFTFDVYVPGDSDSRDELGKVRLIDINPWAPRTDSLLYSWVELLELKVPGPILGSVVNEEEIIRIGPGVNEEDLVDGSGVEETTDDEDVDELVPELRLVEKDNPAAFNFSTPQYSAHKLPKEVVEASMSGDGGLREFAQRWKEMTEAEGGGDVWENPPTAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5J9</accession>
    <name>A0AAD8U5J9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_201338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357717.1">
        <property type="nucleotide sequence ID" value="XM_060501656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5J9"/>
    <dbReference type="GeneID" id="85385555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042158231" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8148" checksum="0A4F7DBDBDE15552" modified="2024-05-29" version="1">MVRLVFFHPCLRVWGCIWGSGVCPRGLSSSPKPRLCEFLGHIDLLTWHQLGNMEGRPGSWMTSGPSNRLPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5K3</accession>
    <name>A0AAD8U5K3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_191793</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000226">
        <property type="protein sequence ID" value="KAK1706426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357826.1">
        <property type="nucleotide sequence ID" value="XM_060501601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5K3"/>
    <dbReference type="GeneID" id="85385500"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001530">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="738"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="812"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="840"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="920"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="953"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="51"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="376"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="697"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="1018"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1706426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1271" mass="138547" checksum="D352C4289FDACA5A" modified="2024-05-29" version="1">MEKREVSSERENHDPSDGNHSGSHSKPTNGLKGFFRIFRYGGPTDYVLETVAVVAAIGSGAGLAMVNLVLGQFMDIIANYTTGAISSDEFMAGVSKFCLYFVYIGIVRFVLTYIYATIFTYVAFNITRNVRCAYLRSTLRQEVSFFDHGTAGSISMQATSSGKLIQSGIAEKLGLVFQNLTTFLAAFIIAFVKQWKLALIISCIMPALLITMGSVAIPDAVIDSKIFPIYAQAGTYAESILGSIRAVKAFSVESRILEKYTTYLASARQLGNKKSPLYGVMFGGQYFVIYAGSGLAFWQGIAMVARKEVDGVGTVFTVLFSVIIASTTITAVAPHMVVFSRAATAASKLFALIDRESSIDPFSELGAKPEKVSGTIDIERVSFSYPTRPDTQVLKDFSLRVPAGKVTALVGTSGSGKSTIIGLLERWYDAQAGLIKLDGVDIRTLSLNWLRTNMRLVQQEPVLFNATVFDNIANGLVGTPWATATHEEQMVRVREAAKLAFADEFIVNLPDGYNTRIGERGGLLSGGQKQRIAIARSIVAQPKILLLDEATSALDPHAEGIVQKALDSASKDRTTIVIAHKLATIRNADNIVVMNKGRIVEQGRHSDLVAAGGTYAKLVQAQNLSVDHNNQSDDGSDNESTQAIEETQSLAKYNTADAQVLASFKDRENFALHTQTGLFHTVMKLVVSTPEIKSWYLLAMCTCLLGAAVDPGQTLLLAKVMSAFTAPDMVQRGNFISSMYFVMALGCMIVYFVMGWATNVISQTLGQKFRQDLFRDILKQDLRFFDRPENTVGSLTSRIESNAQAITELMGFNVALCLMALINVLASSILSIAISWKLGLVGVFAGMPPLLLSGYARIRIETKMDADIDSKFSASASIASETVSAIRTISSLAIERSMLQRYSSELDDAVSNSTLPLFQLMVWFALTQSVEYFILGLGFWWGSKLVANGELTFSQFIISFMGLFFSGQAGATFFSYSSSFTKAKTAANYCFWLSNLMPTIREKKETKGKGPAVECQMIDFREVQFSYPLAPDNRVLKGVSLKIDRGQFVAFVGASGCGKSTMIALLQRFYDPTSGSIVIDKIDSLTDLSPRLYRSKLALVQQEPTLFPDTIRENIKVGIDFDSHEGVVADDSVIEAACRAANAWDFVSSLPEGLNTPCGHGGSQLSGGQRQRIAIARALVRNPDVILLDEATSALDTESEKVVQKALQEAAGTGNRITIAVAHRLSTIRDADKICVFYRGRIVETGTHDELIELGGMYKKMCEAQSLDRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5Q8</accession>
    <name>A0AAD8U5Q8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000226">
        <property type="protein sequence ID" value="KAK1706422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357822.1">
        <property type="nucleotide sequence ID" value="XM_060515029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5Q8"/>
    <dbReference type="GeneID" id="85398927"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF13">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="27361" checksum="D9352E5EACB5A887" modified="2024-05-29" version="1">MAAVSHKARSLGIVFAHGGFHLPACFDLAKARLEKAGFSPVVAVRHPSVGTDPKITVDDDARNIQAEIAPYLEQGKEFLALAHSYGGSPLTIAAKGYSVKERAAQGLKGGIRAIVFVTANMPPKAGASALSVLPPGLDIVDIADGLVMANAKAKAAFYGPDMDDKLADECMATLLPQSQEALLGPASVGSEELTVPVYYILCEKDQTISPATQEQIISTIPTLKRVLRNPGGHSAFITEVEKFVEQINEIADEVERDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U711</accession>
    <name>A0AAD8U711_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000251">
        <property type="protein sequence ID" value="KAK1705026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357528.1">
        <property type="nucleotide sequence ID" value="XM_060509749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U711"/>
    <dbReference type="GeneID" id="85393648"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="31252" checksum="F41AB86F1DB085D1" modified="2024-05-29" version="1">MMPATEIGPPISGVTPSSNHLIWEDISLVINSINLSISTVRRDGPLDPVLFLHGFGSTKEDFTDVIHHAPLSDYPLLAYDAPGSGTSTSSDYSAISIPFLVAVAEAVLDAHKIKRFHLVGHSMGGLTGLLLAQRNPGAVLSFTNIKGNLAPEDCFLSRQILDFPANDTEMFIASFIERTRRSADYGNGMYAASLRSKVRPEVVRPTFESMVHYTDTGDLLKVFEGLPCPKNFMFGTSYKKLSYLSQISQAGVELAEIPNSGHFVIYTNPIAVWNSIAKFLSNAVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7A9</accession>
    <name>A0AAD8U7A9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000174">
        <property type="protein sequence ID" value="KAK1710056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358752.1">
        <property type="nucleotide sequence ID" value="XM_060506448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7A9"/>
    <dbReference type="GeneID" id="85390347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="11975" checksum="CBC97E25FEDF98F7" modified="2024-05-29" version="1">MPSVKNPNGPSKNRLANKALGAKIARRKKSEANKHKIARTDTMRGARPGLMATSGPNAPMSKKKAKKMEKKIAHAMRRKMEAEGEVVMQDVEETAEKSEEGDMETETIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U874</accession>
    <name>A0AAD8U874_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_191336</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357838.1">
        <property type="nucleotide sequence ID" value="XM_060501597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U874"/>
    <dbReference type="GeneID" id="85385496"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1706438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="276" mass="31377" checksum="476B0FB2AD578C66" modified="2024-05-29" version="1">MAQDMGFQRDPKHWVSHDASLATEEDLEIRRRIFWGCYTSDKLISLILGRSVYLFYDDAEVETTNRLPDFPEMKPWLPAGFSDYDGGFGAVNPLIPCFKEQIRLSKVIEKMLSKLFSTKSSLEGIGRQSCIDSLNFELCSWYEALPDCAKWNRWEPPSTLLIPSVAALHLLFHSVRIALNFEQAVSHNVAALKDNARKDCLSSAEDIAHIVRKYRSQYGLGHSPLMMIYGVMQAVRALSLFGTPEEAQYLLHVLDECSSAWTLAHQARDRLTRGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U911</accession>
    <name>A0AAD8U911_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_79233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359742.1">
        <property type="nucleotide sequence ID" value="XM_060515753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U911"/>
    <dbReference type="GeneID" id="85399651"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_bL36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052143">
        <property type="entry name" value="Mitoribosomal_bL36m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46909">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46909:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL36M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165797" description="Ribosomal protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="12685" checksum="6B2465A931BA10BC" modified="2024-05-29" version="1">MASTLAVSLRALTLSTARATIPRAASTTAAATATRALSTAILTKQPAQKSESMLTQVGKSASGVVNAVVQQTRGMKVHSSVKKRCEHCKIVRRKAGKRHNGYLYVICKANPRHKQRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Q5</accession>
    <name>A0AAD8U9Q5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_640103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000165">
        <property type="protein sequence ID" value="KAK1710892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358952.1">
        <property type="nucleotide sequence ID" value="XM_060509468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Q5"/>
    <dbReference type="GeneID" id="85393367"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="69" mass="7329" checksum="426DF3F4B97F2E8D" modified="2024-05-29" version="1">MAVRKLVGCLESSSDLTRHRLGSCDAGFSVLTVPTSSHARYWSSTQKKGAATPTTSTGSMQGLRCRIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAL4</accession>
    <name>A0AAD8UAL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_95871</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359462.1">
        <property type="nucleotide sequence ID" value="XM_060516028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAL4"/>
    <dbReference type="GeneID" id="85399926"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF140">
        <property type="entry name" value="FMN HYDROXY ACID DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146046" evidence="6">
        <location>
            <begin position="16"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="7">
        <location>
            <begin position="40"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="121"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="305"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="328"/>
            <end position="329"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1712605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="41662" checksum="B12210293D84AECF" modified="2024-05-29" version="1">MRAALISALAAGAAATRPFLNEPDTGIELALGDLAVGALSNLTQMVGLPDFEYAARNYLPIKNYTYYRNGAAGEWSYRNNLEVFGRYRLRPRTMVDITNIESTLNTTILGHNFSAPIFISPAARADYAHADAELNLMRAAAAENILYMPALYAAKTIEQIAEVKAEGQVAFQQVYLTTNDTATQVLFDRIKASGANGIVYTVDSAADGNRHRAARFAVGSADSDYSLITWDEYRKLSNMTDLPIIIKGIMTVEDAEAAIENKVPAIILSNHGGRQLDGSPSSLEVALEIYEKDPEIFQKIEVYADGGVRYGADVLKLLSLGVKAVGLGRPIMFSNIFGQEGVEKAIQILKHEIAIDAGNLGVPDLKKIDASYVKWTPNNWYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAP1</accession>
    <name>A0AAD8UAP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_685007</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000213">
        <property type="protein sequence ID" value="KAK1707321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358009.1">
        <property type="nucleotide sequence ID" value="XM_060511247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAP1"/>
    <dbReference type="GeneID" id="85395146"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932066" evidence="5">
        <location>
            <begin position="26"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1707321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="607" mass="64648" checksum="0074AB762F95CF0D" modified="2024-05-29" version="1">MLVKSSLALASAALVLGAASSSSSSQPYGDTYDYIVVGGGTAGVAVAARLSEGLPASKILLIEAGPAVWDEPKINVPGMKGSTLATKYDWNFTTVPQPNVNSRTFTVNRGKVLGGSSALNLMSYDRAAVAEYDSWEALGNPGWNWEAMIAAMKKSENFTGINTDTYGSEGVGDSGPVKAVINRIIPEHQKTWIPTMNALGIESNLESLGGDPLGVMYQPSSIDPTHYNRSYSANAYVPVAGSNLEILSDTTVIKVNVGKATGNLTLQAATGVTLSDGTIISAQKEVILSAGSIQSPGLLELSGIGQSSVLNASGIEQVIELPGVGENLQDHLRIQSSYQLKDNYTSFDILRSNATYAAEQLALWNAGQVSLYDYTGSGYTFTTWAQAIGNDSRLVSLAKEAAGEDPSVVDQKKLEFLTDPSIPQLEVIFSDGYTGVKGYPASTSPLFGEGFFTLIAAIMHPMSRGNIHISPANTTGKPVINPNYFAHEHDLEAAIQAIKYCRKIATTEPMRSIWENEYEPGLDVVETDEQWKQFALNTTLSIFHPVGTCSMLPKEDGGVVDSDLKVYGTSNLRIVDASIIPLLISAHVQTAVYGIAEIAAERIIADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAU8</accession>
    <name>A0AAD8UAU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitination network signaling protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_724531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000206">
        <property type="protein sequence ID" value="KAK1707721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358099.1">
        <property type="nucleotide sequence ID" value="XM_060512669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAU8"/>
    <dbReference type="GeneID" id="85396567"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="387"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="766" mass="85361" checksum="DF43BBB93F7CC3E7" modified="2024-05-29" version="1">MPSLVTVLCMDVFILLVWLFLWPPMQLAILDFAKPVIAATLGGGSNTREGASRSVTTCFFLVIGSHLLRGSRFHWTRATKFLPANWRFSPDSDDPLETFTRGFDKRGPHGWIKSVLAIHILTQGIVRYIREWYLRREKGSPSTHSITDPEAGKSYSNETTTDTGFATPDSDTTFQQNATVSSTKKKRKQSTQVRLQQPLWAALASTKIVMVKEYELSHATSESAGSNATDIHNLGNAPFDSQAEQIWISYIGHDEVCFNTSYFPDSPSAAANGHVSRPAGVDTSKPFYVRVNNAFWQPTRIFRIQDDDDQDEQSSQHRWCGDIYGLRPLSKYVCEFVDTRTNRVVFSTSIRTSFAPNKDQEGSVNPPVSTPQSLRPDSPATTLKSTINANNERLAEEKSRLKTLRKEWKNKIASLRKENERLDNVIQTAGGNDDKHRQKIIQQETNKAQSEKEIAQLEAELKEFEKAPEGFYERKKQTEKEWAAEKAVFDTASKEYKEYKAAIAKAVKAKEDEQAAAQTKRNKIAARIAKVDTELGRITDANNRGLDEAERRRQARIAWQAETSTIENNFRGSIADIKAANANKQEQVNALLQQLQAYHEHMNYATTAAMPYDLPERHSAQPQTTSSAYNPAAPAWTPPSAAASQYVMPAGPMWPTSTMTASGSVLPLPASSMQPVWGYPPTHQSTVSLKARGRSSSMLSDVSGFTQSSNGDDEFLSLHNTPAQQPMAQRTPVTFAFTRLKGSELICDLSSIGRFMGLSVKLGGWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB57</accession>
    <name>A0AAD8UB57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_757768</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358575.1">
        <property type="nucleotide sequence ID" value="XM_060514937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB57"/>
    <dbReference type="GeneID" id="85398835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000394">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF38">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="54"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="53272" checksum="E3A34CEB3173EA20" modified="2024-05-29" version="1">MSFENGRKQSLEMKEDKNAPVVSEADAELAEALRNYVPGTREEKQLVRKIDLYLMPMLWIMYILNYVDRTNIGNAKIAGMQKDLSLTDDGYAWVLSIFFFGYLICEVPSNMILSRSRPSIFLPGIMLVWGALSALMSISKTYSALLGFRFVLGCIEAGFFPGVLFLLSCWYTRAELGKRFAIFYTAAVLSGAFGGLLAGAITANLHDAHGIAGWRWLFIVEGVATVGVALIAFFVLLDYPATAKQLTPAQRQLASIRIIADGIASGGQNKARLSHWKAFVAAVSDPRTYMFIVLFMLDVGAGTISYFIPTITLTLGYDTVKAQYMTVPIYAVASVCLNIVAWSSDKHQERRWHVAAPLGLGFACAVVCAAVQTPIVRYVMVCFLAAGIWSALPLVLSWTSGVISLPAEKRAIVLAMVNAFGNFSSVYGSRIWPSKDSPAYHTGFGVTAGFLGAGMIIAILIPILVKMVNWQGTKAEREVLAENELEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBB3</accession>
    <name>A0AAD8UBB3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_155013</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="JAHMHS010000193">
        <property type="protein sequence ID" value="KAK1708657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358339.1">
        <property type="nucleotide sequence ID" value="XM_060501352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBB3"/>
    <dbReference type="GeneID" id="85385251"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1708657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="460" mass="52434" checksum="4CCA3B6D70E69B00" modified="2024-05-29" version="1">MMARTRRGVKFPHKANGHGEGRRSSFSDVSEDGSPTKQRSGAALENIVEQPQSPEEEKRAAYEKKKANFLTRTFWTFVMFAGFFTALFMGHIYIICIMTAIQIISFKEVIAIASVPSRARQLRSSKSLNWYWLATTMYFLYGESVIYYFKHIVLVDKVLLPLATHHRFISFILYIFGFVFFVTSLQNGHYKFQFTQFAWTHMALYLIVVQAHFIMNNVFEGMIWFFLPAAMVITNDIWAYLCGITFGRTQLIALSPKKTVEGFVGAWAFTILFGMLLTNVLMRSDFFLCPVNDLGANIFTGLECTRNPVFIPKTYSLPPLFFLPPNMHQTFSFTVAPMQLHTLVLATFASLIAPFGGFFASGLKRTFKIKDFGDSIPGHGGMTDRMDCQFIMGFFTYMYYHSFIALHKVNLGSVMEMAVTGLTVEEQLELVRGMGRYLSNQGVWGDEIIQCLDKALQAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBW7</accession>
    <name>A0AAD8UBW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C4-dicarboxylate transporter/malic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_636539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359968.1">
        <property type="nucleotide sequence ID" value="XM_060509259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBW7"/>
    <dbReference type="GeneID" id="85393158"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="462" mass="51446" checksum="E45740E966C2B1F4" modified="2024-05-29" version="1">MDRRDPQHSAWTESEVSTRKNSAEWQTSRPNSPKLAPLDLGFVDEKKGKETEKDGYNTSITPVVEKGTTPHAAAHSHLRDVPGLGMIDINDPNRPRMGWKARIHHFTWAWYTLTMSTGGLALLIFAQPHQFPGLRQIGTVVYVINIILFVLVCSAMLTRFFLYPGDMKKSLTHEREGFFFPTFFLSIATLITSTNRYAIPENDETLVWAIQVAFWGYLIVTLMLAIGQYSFVFARHNFGLQTMMPTWILPIFPIMLTGTIASVIADTQPEIAAVPIVVAGLTCQGLGLSVAVLMYAHMVGRLMSAGLPHREHRPGLFMNVGPPAFTALALIGMANGLPNNLDPDRDGIIIDAGIIRTIALMSAIFLWALAAWWFGIATIAVISSPPVYFHLGWWAMVFPNTGFTLATITIANQLGNEAVKWFATGMSVCLLGAYCFVLYHHIRAVVIQDIMYTMRDEDYNDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBZ8</accession>
    <name>A0AAD8UBZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_735949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000215">
        <property type="protein sequence ID" value="KAK1707147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357995.1">
        <property type="nucleotide sequence ID" value="XM_060512979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBZ8"/>
    <dbReference type="GeneID" id="85396877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="34269" checksum="5C1697EBD72BF676" modified="2024-05-29" version="1">MKQQHLVIRIHKGLTAYHLWDFIRDSEQQSTPHLKVAIDRALLPPHPSPAVTYPYLFRPSIFFPRSLPHYYFFRFPLNAQTKSFRATLSSNAGSNAEVGFTRRIASNRESESLRPEPCAHSWLIHDSSNMCSVHRYNVHPRTPASVTIVHSLLFGRPRHPVTGYTASHLDMRSPSWAQLDQPRATSAVPGHSITCRGCMVTHKCVPNRKRNGAKVATICNQSHPSTRRRFVQAVSLLAHGPLVYVQMPPSLYPKNRSPTLVPGKQGYSSMITWLGLVTKPTDVEVRLSAAELSQTTSRKGRQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCD4</accession>
    <name>A0AAD8UCD4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_640513</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358849.1">
        <property type="nucleotide sequence ID" value="XM_060509493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCD4"/>
    <dbReference type="GeneID" id="85393392"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121517" description="inorganic diphosphatase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="338" mass="38702" checksum="7261989761D36241" modified="2024-05-29" version="1">MSNRYFFALAALSVLSSAARTSSHSFNYSALRLREVGARNTEDWRIWLEKDGDPISFWHDVPVWPDESNKQVVNLVVEVPRWQDGKIELKRSEPLNPIVHDSLNGAPRYVENVWPHKSYPFIYGSIPQTWESPNYNHSFTHLLGDNDPVDLFDIGQDRGYVGQVKQVKILGGLALADGNETDWKILGIDIKDPMASVINSFEDVEKYRPGTIKTFRNWWTHYKVARGDPVINIIGDWYQNVTYMQSVVEESHKTWADLIRGEVDSNEINYNQTSRPDVENSFVNKATTTAKFNIPAESRIDPAAPRPEKADGWYYLDSDANLIVVPQTQQTFLNRQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCG2</accession>
    <name>A0AAD8UCG2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_757523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358864.1">
        <property type="nucleotide sequence ID" value="XM_060514909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCG2"/>
    <dbReference type="GeneID" id="85398807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF503">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="462"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1710585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="701" mass="78540" checksum="1591D09D22CF142D" modified="2024-05-29" version="1">MRRDTDSVPVWCAVLFAASGVFQVDRLYDDSTRLWAPYRWAWYLGLIRECIDIAQLVMARESSASSCLSLFLASWMLVLYAILHYSIRPGKGSSQTPPAQSKTQSTMPGKGNIENIHGIRFDLGRWTDSFRTFKRFIWPSDNAPMKVRLLFIVMLTLGRKGLEHWASQTFGRIIDALADSDVWSPGSMLLVTWAISRFCVLLVRVPKQWMWLLLRAYSEENLDKAIFAKIMSADATFHTLNNPARLHNAVDNAQGVRSSFDALVEASVDALFATCVTIPAAARKFGRHVMAVMAIRLIVLFINFRRGTARSHRANGQLLATQKFHKEHREDKIRGWRTAAVFGQLAHQIAENDKSVERLHRSVSQFQREALTCWAYRIMAEDAGHVISVLVVCAQVFLGTSTPGDLAVFNLHWEQITTPATLLLQGLEGIMKNLQDAAEVAGIMDMDSKRLVNRLRSIEGRIELRDVSVSLGGQVVLDCFNLEIPSKKKVALVGPSGVGKSTILGLIAGQIEPDSGKVLVDGQDLREIDRHSIPDHIGILEQRPHIYNTTVKENILIGKREATMGEIEDACKKAHIHDDISRREMGYETPCGVDGRNFSGGQGQRLSIARLLLRRPRIVLVDEGTSFQDAITESLIKKSFSEEFGEMTVFFTGHRFSSIMGAEEIIVLGKKGSILQRGSHDELLALKGGKYWEYWQNHLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCK4</accession>
    <name>A0AAD8UCK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polyamine transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_757443</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358924.1">
        <property type="nucleotide sequence ID" value="XM_060514898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCK4"/>
    <dbReference type="GeneID" id="85398796"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="46"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1710864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="53154" checksum="27052D948C61D8D8" modified="2024-05-29" version="1">MGPEEIPSEIPSGEISDGDDRNIVTWDGPDDPQNPMNWPDSRKWLNLALMSLLTIISPLGSSMFAPGIPRILAEFKTNNSLIATFITSIYFLGYAFGPLVVAPLSELYGRVYIYHISNVLFVSFCVGAALSTSIDMLMAFRFLMGVVGSVPTTIGVGSIVDVMPIEKRGRSISLWAMGPLLGPSIGPVAGGYLIQAAGWRWVYWLLAILGGVCSILALLIMRETYAPILLERKARHLRKETGNQALRTKADRDGKKLIQRAVIRPFKFLFMTPLVSIIAAYVGIAYGILYLLIATFSFVYTDQYHFSEGDAGLAFLPAGLGMMIGVLTFGNVQDYLVKKAKERMRPGEKYRPEVKITPWLTIPTGLTIPIGLFIYGWTTEYKIHWIVPMIGVVILSGGLTGVTMCVQNYQIDSYERYAASGSAAVTLSRSLIGALMPLGGLKMYDALGLGWGNSLLGFMSLALVPVPVGLFFYGGMIRKRFDPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDF5</accession>
    <name>A0AAD8UDF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Hypoxia induced protein conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_589259</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associates with the respiratory chain complex III/complex IV supercomplex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RCF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359744.1">
        <property type="nucleotide sequence ID" value="XM_060506216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDF5"/>
    <dbReference type="GeneID" id="85390115"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097250">
        <property type="term" value="P:mitochondrial respirasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050355">
        <property type="entry name" value="RCF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297:SF3">
        <property type="entry name" value="HIG1 DOMAIN FAMILY MEMBER 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12297">
        <property type="entry name" value="HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="12">
        <location>
            <begin position="15"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="150"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1713418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="25700" checksum="9503BB93B398D41C" modified="2024-05-29" version="1">MPGPDGKPSLLDQPMPSSFDENNEFYDERVLHKAFRKLKEEPLIPLGCGLTVFAFVNAWRATRRGDARQANKMFRARVAAQGFTVFAMLAGSMYYNKDRERTAELRKIKEAKDAEEQRQRWIRELEARDEEEKALKARMLQRRARLDAKNTGEDTLAEGEQGKTGGVLGALGLSAWKKPEEGDATATEKPAEEKAQKKENPKSSLGAIGEIYGRKPSPSSAEGSSEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEA1</accession>
    <name>A0AAD8UEA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_583193</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362371.1">
        <property type="nucleotide sequence ID" value="XM_060505628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEA1"/>
    <dbReference type="GeneID" id="85389527"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13993">
        <property type="entry name" value="STKc_Pat1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000693">
        <property type="entry name" value="Serine/threonine protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="436"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="594"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1722316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="656" mass="73566" checksum="CA2707DD7C131745" modified="2024-05-29" version="1">MACLRDNFQNGVLLGGRYETISPLNHGSFGMVFMARDTKTSETVAIKCLTKKEAADEYGFDFAIDEKSEELVLHSRLGSHPNIVNLLDTFETDAHLYLVLEFCPQGDLYEAIRKGHGPLETEHVRQFMLQLVDAVDYIHSKGIFHRDIKPENIFLTQSGDMKLGDFGLATTENWTLENTVGSDRYMSPEQYDSAGAGYSPAQADIWAIGICLLNILFSRNPFTTPTEADPLFLDFSRDKQSLFDVFPSMSLDTYEVIVQCMSLDPKKRSLAGARSALQRVISFTTSEEDDDDFCSAERHVMASANREPLRTPSIQSPQVDQGAFPWAKALHASPPQPIRQLSAIPDEDLFSKSGETQNSDWFSSAQAPSISSTLNSSLGISMQSLHIGRPMKAAPRPIPKVSPMAGSLPINMAKPRSNLSSMSLVFGRKDAVSKSWSDMWDEDEEEEEAEREREMQSLKDLNSRTWSQDGKSDDKEDDCETVDATPLATTPQRSFHDSHKLIHNDIDSDLAADGFFFQQPSPPKAKPMLPTYQSSPPKRDNVDKWAALGQRRRGLTGSSYSHMSPEVPRQRAIGLGYNSYAAGANSFATAAWEHSGHHHHHNNHNNIHHITQKQSPKDKVKDCPWNKGRDWNYWRKEKRNDLADVEWVGGWQEAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEB3</accession>
    <name>A0AAD8UEB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_654841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361427.1">
        <property type="nucleotide sequence ID" value="XM_060510758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEB3"/>
    <dbReference type="GeneID" id="85394657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="698" mass="75558" checksum="2BCC2A4CA5C35DEB" modified="2024-05-29" version="1">MSQPEPSTQLDQEQQASNVLKAMKNASETVRGAIASAIPVASNQVLTVSLPGSCPTDKRLPNLKQVGKTGKSVARSYLAALDLLVPVEASVAGVVSNETTDVTDPRLKTIQERYKYSMRYLTGPDDTPSGNGRTKVETYVMKQAAWAKEAAAYQHAQAQALERLSPPPGATTAQIKAAQDNSWLQVYGSHSRATEVCVDFHFGVVDISSGMKRIENSKEAFRNLTVIASDGSSEYNGVVLTPSSWATMVAKKTLNWTKNHSKPNPSEIRAEIRRLKSLLISHETLKLAITEDTFFPVLSSNTGDDQTNVKAAYAQVYSDMDTKNAASRGQDERGSVKTDWLKNRFGVTVPAENVLENLIKQQKTQATSSLDRNNRSVRENTEASKKTAGIWIDKRLEQINQDIEELNKQLASSEAAPSSTAPPMLPVVNSEGIIVTGDELLANPSLKNPSATSVIDLDNEESWRNIADGGADSWTKLTYNKISCKVKSNSSSAETSASQSASTVCARAGWGWWRTRTSTTHTQSSSEAMQSMSNLEVEVNMNCMVVEIERPWLHSELFVDAELDSGAFLISPGEDALRDAFDNGKNLIGEYQQFSSYPTAFVVAADIELSFSGDTSKLESAVSASSTSPNLSVGWGPFAISGSHSSSKSKSRTKMESTATGCRISVEAPQIVGWVQTLLPKLPKPKDGDSAMTSPFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UED6</accession>
    <name>A0AAD8UED6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_588747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360006.1">
        <property type="nucleotide sequence ID" value="XM_060506168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UED6"/>
    <dbReference type="GeneID" id="85390067"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="220"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="3">
        <location>
            <begin position="343"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1714544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="427" mass="46924" checksum="DB23D6ED4B854006" modified="2024-05-29" version="1">MSEYTAGAAGMTAVDNRDWETAITQLSKAIKVIKSPKWLIGRSKAYIGTKDFRRALRDAELAQVAAAGRNNRPFMADAQYRRAVAHFRLGELANADTCATWAQRMVEGKSMAELRAPEVDDKGFAQGTRKVLQDEITAVRQTEDPAQSKFGAIWNSICALRLQILGGLEKLAEDDEKRKVTVKFAPDVSLDAPDTDEVEEFTKEEIEVAKAEAVAKPQPKKDVRVDFFQSSTTLTVTVFAKNIPKDDFKVDYGEAFQQISMSHIPGHEPSYTIHLHGRIDPAGSKHTVTANKIEFQLKKAEAVKWPTLQRPADSVAPAANKSNPSPATTAIAQPKAAATSGPAYPTSSKSGPKNWDKLEGADDDDSSDINGFFKTLYKDATPEARRAMMKSFTESNGTSLSTDWEDVKNRKVETVPPEGVEAKNWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEE1</accession>
    <name>A0AAD8UEE1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_794192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362712.1">
        <property type="nucleotide sequence ID" value="XM_060515806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEE1"/>
    <dbReference type="GeneID" id="85399704"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27533" checksum="490B31985A0B5E73" modified="2024-05-29" version="1">MGSDEDQSLVGKHEEAEKQRPHYPDSDGAKHQTECSTTSALNGSQAARRLTLDGLLPEIQLQVLRNLSDLDDLHAAICASPTLHKCYLTARRGLLYYHLGKTFRSHRVLVDAFAAYKLGILRESTSEDKLKLLEEFMDTYIKLQSDPESFRAVYTVDDLASIARFYSLIVKSVLSWLLRQWGRQEAKDCSVSSASATERIRMIRGLYHFEMWCSYYGLGSITARLLPTTLNADMLRFLNKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFA5</accession>
    <name>A0AAD8UFA5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hemolysin III family channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_722744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360659.1">
        <property type="nucleotide sequence ID" value="XM_060512502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFA5"/>
    <dbReference type="GeneID" id="85396400"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="36708" checksum="BA20E4CA19FE88C9" modified="2024-05-29" version="1">MTAPETADDTTGLRNRRRSSSSSHDTTTLLSTVESSAAALERKVEKALLVLWDDLPAWRRDNQFIITGYRPDSNSYRASFRSLGYLHNESVNIWSHLLGAVAFVITGAVLYAVIAPRYESANDADMLVFGCFFAGAVACLGMSAAYHAMSNHSPEVAKWGNKLDYSGIVFLIVGSYVPAMYYGFYCHPALLKFYLTTICLLGLGCGAVSWIEFFRAPEWRTFRACMFTALGTSGVVPVLHGLTIYGRQEMEDRMSLNWVVLHGLMYIFGAFLYAFRWPERSFPRTFDIWGSSHQIFHFFVVMAAVTHLYGMTKAFDYHHTVTGGKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHJ4</accession>
    <name>A0AAD8UHJ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase-like protein family 88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361769.1">
        <property type="nucleotide sequence ID" value="XM_060512422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHJ4"/>
    <dbReference type="GeneID" id="85396320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF9">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042207439" evidence="2">
        <location>
            <begin position="20"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="42269" checksum="DD5B9848A2EC5E8E" modified="2024-05-29" version="1">MRASAPFLALAGTLALAQAPSRPYSTWLASSFVARKAPIDAGYGPAVLYEGIARVAAAASNATLLRAAETAVSSLVSDAGILDGWDPEWYSLDDIRIGNNLLWFYQRNTTAGAKYKIAADGLRQQLNRWPRTPSGGFWHRAPIYEDQMWLDGIYMADSFYATYVSLFEKGNTTAWGEIALQFDLIEEHTRNHTTNLLVHGYDEAKDAVWADPVTGASPLVWNRAVGWYFMALIDTLQVYPKNLPGYARLQKYFVTLADGLARSQDASGGWWLIMNEGYQTRKGNYLESSAAAMFAYGLLRGVRDGFLEAKYKDVGLKAYKALVRDFIRDDKNGLISFTGTVQVGSLNSNASFEYYTSIPIVENDHRGSGSFMFAAIEAELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP9</accession>
    <name>A0AAD8UHP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_350360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364542.1">
        <property type="nucleotide sequence ID" value="XM_060502519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHP9"/>
    <dbReference type="GeneID" id="85386418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="29395" checksum="34531FAABBF6E4A3" modified="2024-05-29" version="1">MELCQVKSRRKFVTRSGTVRLSVACLGLFACHDPFYLREKVVRGLFRHGEASQWKGPANQMLRWNFVATPCLLRFLPPPPPKKIEMQTSITTVVSSSIDRSPPSERRGNISKVGRPVVKGKPKHTCKRDLEHSKLPTPMFPYPRSPSVIMVSRMPCPQCVLVYPATEKEKKTSQSLPAQVRERASSKHPPRLTDNQGRLLQCGKKSERGHTERRERRWGRDSTPLALPLIILPLLDLAVLVIGLQLLCSSLVELPLDRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHQ4</accession>
    <name>A0AAD8UHQ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Malate synthase</fullName>
            <ecNumber evidence="3 10">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_579169</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="3 10"/>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364201.1">
        <property type="nucleotide sequence ID" value="XM_060505211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHQ4"/>
    <dbReference type="GeneID" id="85389110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="11">
        <location>
            <begin position="162"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="13">
        <location>
            <begin position="411"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="536" mass="60636" checksum="4E213CE73BE718EF" modified="2024-05-29" version="1">MVQSTLDSVAILGAGNEASRRILTKEAVNFLAILHRSFEPTRQHLLKLRQQRQIDTDNGHLPDFLPETKHVRDDKNWRGAQPAPGLVDRRVEITGPTDRKMVVNALNSDVWAYMADFEDSNGPTWDNMIQGQANLYDAIRRQVDFKLGEKEYKLRTDRTLPTLIARTRGWHLDEKHFTVDGQPMSGALFDFGLYFFHNAKELISRGAGPYFYLPKMESHLEARLWNDVFNMSQDYIGISRGTIRATVLIETISAVFEMDEIIYELRDHSSGLNCGRWDYIFTFVKRFRNRPGFVLPDRSDVSMTVPFMDAYVKLLISTCHARGVHAMGGMAALIPRKDDPAANAKAMDSVRADKLREVKAGHDGTWVAHPALASIASEIFNEHMPTANQIFKRPEAKVTRDDLINSVVPGKITDEGVRKNLHITLAYMEGWLRGVGCSAINYLMEDAATAEVSRSQLWYWVHHGISTAEGTKLDKTTMLNVLDEVTKELLKSAPANNKFELAAKYLRPQVTGEDYADFLTTLLYDEITSVGPSWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHU2</accession>
    <name>A0AAD8UHU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_654471</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361919.1">
        <property type="nucleotide sequence ID" value="XM_060510721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHU2"/>
    <dbReference type="GeneID" id="85394620"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="48"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="58283" checksum="A7E7C3519345D180" modified="2024-05-29" version="1">MSVKSVNVGRLNAVNSIASTNNSEPETNQHGHLTLWQSIKKWRRVVLYCIGMTSAILMYGYDYVIVGTVSAMPSFQHDFGQQLNGKWILPSLWLGLWNFVSPGCSMIGSLIGGVFQDRYGRRASLALGSFLSAIGVAVCFVSNLSPDIHTRRIIFLAGKGFQGGAIGMVMTTSQTYMSEILPPNLRGPLLAFFPIFTLLGQLTGAAVIFACLNLANGYTICFASQWPFSALPLLMAFLIPESPTYLIRRNHNSQAHRAQLKLDPPGADPEDTLDTIRRNIEHERRLTNATYVDSFRGVNLRRTLIIMFSNSLPNIFGLTLLSKSSYFVQVVGMKANLSVIVLILGLVCGLIANIMSVWVLSRVGRRRLILSTLSVLSIIWTAMGIAGCWSGPVIPWYTSMTLIAVVIVAGLGVWPASHVVGAETSALHLRSKAQAIGWFTAGANNSIFGFVLPYIFNPDKGNLKAKTGFVFAGLCALGLVIAFFLVPEMKGRTPAEIDRMFELRLPARQFRHWTNSASEGEKNGSARVENSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW4</accession>
    <name>A0AAD8UHW4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_388265</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363523.1">
        <property type="nucleotide sequence ID" value="XM_060502762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW4"/>
    <dbReference type="GeneID" id="85386661"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000012">
        <property type="entry name" value="Transketolase, variant 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF6">
        <property type="entry name" value="TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="15">
        <location>
            <begin position="390"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="568"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1723468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="732" mass="80663" checksum="B086F30FD16480DB" modified="2024-05-29" version="1">MAPSAVPSEPVAQGIVAAKSLNGPNSQFQLTESEKKEVDFVLRTFRCLIADLCEQFKGGHPGGAMGMAAIGTSLWKYAMKYSPKNPNYFNRDRFVLSNGHTCLFQYSFLHLTGYKNMTMEQLKSYHSARTDSICPGHPEIEHEGIEVTTGPLGQGIANAVGLAVATKHLAATYNRPNFPVVNNMTWCMIGDACLQEGVAMEAIQLAGHWKLNNLVVMYDNNQITCDGSVDLCNTEDVNTKMRACGWNVIEIEDGNWDLEAIVRAMDQARNSKDKPTFINIHTVIGVGSAVAGDAKAHGAAFGAADVANIKKTFGMDPEKHFVVSDQVYDYFRQAVSRGEKIEAEWNQLVEGYSREHPELAAEFKKRISGEWVDDWRKFIPAKEDFPTTPTPSRKSAGLVCNPIAAGVNNLMVGTADLSPSVNMIWKGKVDFQNPDLRTSCGINGDYSGRYIHYGIREHAMASISNGLAAFNKGTILPVTSSFFMFYIYAAPGVRMGALQRLQQIHIATHDSIGTGEDGPTHQPIALPALYRAMPNLLYIRPCDSEETAGAFILAMEAKDAPTIISLSRQNLEQYPKFSSRDGVQKGAYVFQEAQDADVTLIGVGAEMVFAVKTAKLLAEKHGIKARIVSFPCQRVFDQQPIEYKREVLQYRSKAPRVVIEAYAVNGWERYADAGYSMSTFGHSLPGPDAYKYFGFDEAVIAPEVAKLVEEVRANGVNSLRGEFRDLNPVHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW5</accession>
    <name>A0AAD8UHW5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_443120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361964.1">
        <property type="nucleotide sequence ID" value="XM_060503121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW5"/>
    <dbReference type="GeneID" id="85387020"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="557"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="892" mass="100146" checksum="35A7F67BD2F29D45" modified="2024-05-29" version="1">MEPDFTDPSHEWWARPSDGCLVPLVLQCGQEPDILPETSRWSRLGKLPSRVSPVLRVSYWAASSLFVPGTRKYNIGFYTLAVTALKLLVAWPVLCMLVCWAGNLGTSAQQLVDARNKKNSRYDNVCVLSTEASSRKRPSSNRHPVEQDAILPGPLQEERPPASEQQYTDNIRLSGSLPPSGPRVDSSPTSLRPRYLCFVKDFEQGIYETVKVSDYLQQHGDDVDLEFVFVSYTRLQFRVATEEELNKHDYPDEATRNANKEVARQDRDILAKWGMDAAKRVGKRAFWLDFECVRNDDGIARSTSSSQDVYRICDIVRAAHSMIIAIGPSANDKVASILANTEPPEYKRENVTPWLRQWGSRLWTLPELLLCPAEYRIRLYALGDQAEPKEVAKRNFAERAWDDAEAVKELVDHFEGSAILTDLRLIEAALACFSRRQTDQFNKGDIAYATMGLFPNRHRPPVNKEDSGFQAFAKLSIANDSGAFLSRLISLSPPDGAPWHRVEDTWGARLSEIFPSVSISGVVGADTVMLDKVYGATIHWDNLEPEPYFDRSFGMRYVVFAGFTYFACFSVPMAFSFFTGIASIVLSDFMRLSIWQVYIWLLPLAVVFALLFPIILISTRGRVKQPAKSRLIGIEGIVDSASIEKHLWGFNHGNLSTTNPQHYSDEHDLRDPQTSTQPSGSPIGSSSFAFTLVDTYLMTVTHFHCRLPPVAILECGSEGGLQRTFLCSYDARTNTFHRQAVLRVNRRGVEQLHRIDKIRLSLAPHPQPNEQTHDTIYDASSSLPSDEMGPMRVQNSIAKTPTLFNRSATWKVEFLFFALCLAGLSTLGPSNSAKPSAIFTFHEWFLVGQIPGFILLQYLPLNQVAICTFAANSIQKSSSLSLTSQKLIIEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI40</accession>
    <name>A0AAD8UI40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_732870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362114.1">
        <property type="nucleotide sequence ID" value="XM_060512905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI40"/>
    <dbReference type="GeneID" id="85396803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42057">
        <property type="entry name" value="F-BOX DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42057:SF2">
        <property type="entry name" value="F-BOX DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00200)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="55809" checksum="A9905620943FE14F" modified="2024-05-29" version="1">MRPTSSVPNISVPSSNPQLGMILLRHGPEYDSRFRKRGHAYGALSLLICILLLAENPVSRTFCRRKVAATCSFFVSNGLRVLFKADEEEISGIWGNDVTILSSVGRGLFSYSKKSRQFGDWEDWKNGEYHAFTSAIKRIKQLPNIRAIELHFSEKCKGRWSNLHDAWDDVEPSETRLNTLKAVFEAIRERAVQSNAEVSTIRSLTIRNLQNMPHQEFVNSGLFKDVAKDIDHYHLLITEEYNEHGPDRDTFMEERLEFESHLQRQFLPHFAANLTALTLNFHECWGTMPGYFDGAGLEFPRLKTLNLGNFVISNNRHFDWVLSQKSLETLRLDSCHIISHIQVDTEETKEWRIHTEDWQRLPKGSYGISYDNAELYRFDGTWESTFDKIRNNLPCLMDFRFDGQFYGLHFLRPSRIDTVLHPSRYINFDAGTCPSPWLTSNSETGEMEFGDYECSVNRSEETKEGDTRAFRDLLSACHERHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJN8</accession>
    <name>A0AAD8UJN8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_620559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365191.1">
        <property type="nucleotide sequence ID" value="XM_060508200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJN8"/>
    <dbReference type="GeneID" id="85392099"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39602:SF2">
        <property type="entry name" value="ACW-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042084388" evidence="1">
        <location>
            <begin position="18"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="29656" checksum="8D07FC8BA63AB607" modified="2024-05-29" version="1">MMNKIVFALAMASAAVAAPLNARQDACQDAYKACIAAGTPEVACSCTLTACVGEDNARNREYCASATANLPKPTSTGIPGGCNPAHPGSCPSSYFTYTTATATAAPAPTFTSISGIPGGCNPAHPGSCPSSYFTYPTLTATAVPTPAPTSGSGGSAPAYPNPKAVEGKTWTIKDMTRYCGEKNDGCDYNFAIEADGKTERCTVIRMPGSNAATESWSDQPCTSGSNFKVSWGYVANPAPAFAVVTVVNGKELAWFGVSDINGKPVTTAPSSPFGSGQFGNLGPEQVYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJS5</accession>
    <name>A0AAD8UJS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364127.1">
        <property type="nucleotide sequence ID" value="XM_060514270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJS5"/>
    <dbReference type="GeneID" id="85398168"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="25068" checksum="FC25793FEFF617C4" modified="2024-05-29" version="1">MESPAAPFSPSTHPPIIMDKLEVGSLYIMISIPFSIYFAKKKHIYATNLPDGPNFPFCTYELMVSQGLSTEEFHWDLYWHASDPATDELITTNVNQYASRSADDDGNGILYRLRPLETCPTIYTRDRLTITRVRSHAQLVGLIRVLTVPPAFILHLTRYLDWMTAESARVAERSYIKGARDHTFHQFDISRFTAELLSFAYAEVPSALSFGGMGMPRPVVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKK2</accession>
    <name>A0AAD8UKK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_742299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363126.1">
        <property type="nucleotide sequence ID" value="XM_060513107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKK2"/>
    <dbReference type="GeneID" id="85397005"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF134">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="541"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="496"/>
            <end position="497"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="542"/>
            <end position="543"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="61803" checksum="A06541A46C8A8831" modified="2024-05-29" version="1">MTQEFDFIVVGGGTAGCLLASRLANTASKPSVALLEGGGDISKPEYRRTAERFSTIAQPGLDYGYASTPQEHAKNREVPQARGKGLGGSSATNFQVWSLGARAEFDAWAAAAGDDAWGFESVIERVKKLENLHLNDLSKEWAEYVKPDPKYHGFSGPIDVSIGHVERETKAFIDAGVDLGHKRNLDPNDGDLIGFSLNSTTSLNGVRVTGASAFLEKNVPANLTYLTESRVVKIVFEKDRAVGVLKENGSLIRAKNEVILSAGALDSPRLLLLSGIGPQADLNALGIPVVKNLDGVGKSFTDHPMIVTCFQMKSGFTERMGLSDPGKYQEAVKQLAESGNGPLLGHFSSVPHAFLKNDRAYESPEFKKLPIDVKGYLLESGVPSYELVIGPLIPPDHAFEQSSDGFFSVFVANMNSVSRGTIRLASADPKDAPLIDPKYLSNPFDLVNLREALREGLNLLKTNTMKDHFVRPIFAPKSDSDKDIEDFIQENVAGLWHPSCSVKMGKTEQDGSCVNGDLRVHGLNGLRVADLSVTTILPSGHPQIVAYVIGQLAAEKIARDYGLDSKRKEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKP6</accession>
    <name>A0AAD8UKP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_408150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362959.1">
        <property type="nucleotide sequence ID" value="XM_060502893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKP6"/>
    <dbReference type="GeneID" id="85386792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="276" mass="31271" checksum="F3C67AF2DEDCE0BF" modified="2024-05-29" version="1">MGNQATQKSAWHSTRPVFHQVGTRCLHYPALNSYVTYVRLRHPGAGSQGLIVNLAPASPSRTCARLSGLTARNLFPIFELLNSSAELLQPTRKLARRYQKMNDSNPTPLTTVECQPTKEGVDDDVIYLGTYKVKDSHLTADHSQSKNGRNSRRPRDEITSNRSGRRKSHQKTTSPTSTLEIPAEMTYKHVKLGATKDSSQLRQAVYGFFDHTGRLRHRIESRRHTTIADLDPCLKPALISHDRIEYRSCFRGLSLRQVRKELRRHIARAHALDGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL03</accession>
    <name>A0AAD8UL03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitin synthesis regulation, resistance to congo red-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_751057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366282.1">
        <property type="nucleotide sequence ID" value="XM_060514001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL03"/>
    <dbReference type="GeneID" id="85397899"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020999">
        <property type="entry name" value="Chitin_synth_reg_RCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28187:SF1">
        <property type="entry name" value="PROTEIN RCR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12273">
        <property type="entry name" value="RCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="181" mass="20237" checksum="353952062EDFECC0" modified="2024-05-29" version="1">MADAVGNVHILPFPIDSLDKRQFYCSSGQVYRNGACYERGAWYWWGRWVLAAVVVGIALLILILLGCMNSRRRRKRGVQPFYGTGWMSNNNKHNQQGTYAYNQPYNGQQQGYAGYPQQGGAYQNPPPAYGPAQQQPQYTGTTFNPNDGYYGGHNEGIHLQQPQNAYQRDSYAPPAGPPPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL18</accession>
    <name>A0AAD8UL18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_277601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365896.1">
        <property type="nucleotide sequence ID" value="XM_060502110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL18"/>
    <dbReference type="GeneID" id="85386009"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.70">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89372">
        <property type="entry name" value="Fucose-specific lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="51017" checksum="B490CA828FEE8974" modified="2024-05-29" version="1">MADAQTYSTLEVDTRQTENGLELHHTESQYLQRTSDFHRKLDNHDHSQANSPQQDEHDSTAKAGRRTTICGLSRRVFIIILVVGLVMLIGAIAGGVAGGLLSRRDNTTKATTRCILSTSRLAAANRTIDENFQKTVFFQDGSGALMARYVLASSTGSTEWTTTNLTSYFKSTVGEIDLPNGAPMVAMSCADWSCGDTSLFYLGTDGIVHDVRDDSGKGGAAWYSDRGGIAKASLRADEGSQLAATLLQRFPTQNDQPVPNGTILVNRLVAYKGQDKSLYVANESVSWAPSELDQIPNLTTNLSLAMITQFGGVILDEISLVAQAVGSNTATTSDFSMVEDRWEGQGWNSQSKNEAILDDILKPQGSSSMATPQFAVTMRNNWLDSIYLALNPDGTIIGRVVGQRNETMDQITLEKSGGEVAKFSAIATTMEGHLYGIVNDTIREYSFDTSDASILHFDGVVYECLTKKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULS9</accession>
    <name>A0AAD8ULS9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_582368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362795.1">
        <property type="nucleotide sequence ID" value="XM_060505547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULS9"/>
    <dbReference type="GeneID" id="85389446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="303" mass="33429" checksum="C55E8532E966C289" modified="2024-05-29" version="1">MPAFTAGDIPDLRDQVIIVTGGNVGLGFETIRQLSKHNPARIYLAARSQDKAEKAIQELQQQNPKATNITFLKLDLASFDSVKAAAADFLRKESRLDILVNNAGIMMTPEGLSWEGYEIQFGTNVMGPALFTQLLLPVIRETAKTNRETRVVMLSSAAHARAPNDIYNFEEIRTTMPSRATTQRYTMSKLADLHYAKALAEREKQVKVIPVHPGMVATNLHHASTGMFLKPFLNAAIFFATPVEKGALSQIWAAVSPDAKSGQYYGPTAKAESGSKLSQDRKLQESIFGWIQKELKGHVDTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULU8</accession>
    <name>A0AAD8ULU8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_615108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366732.1">
        <property type="nucleotide sequence ID" value="XM_060507880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULU8"/>
    <dbReference type="GeneID" id="85391779"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="51" mass="5282" checksum="B53EA05C9959589C" modified="2024-05-29" version="1">MRPLATSLLAGGEWSAPAKGPGVRLGPSGVPSDHRIPPQYLGPEGRDEMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UME2</accession>
    <name>A0AAD8UME2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_360507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364263.1">
        <property type="nucleotide sequence ID" value="XM_060502576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UME2"/>
    <dbReference type="GeneID" id="85386475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14475">
        <property type="entry name" value="SPX_SYG1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="656" mass="74108" checksum="0900DB9214B6CEF6" modified="2024-05-29" version="1">MKFAKELEQDLVPEWRIKYLNYKAGKKYVKAVSRAINRANGSPQNNASKSENRIAANFFHSHSPFNNQKHGHSRGGNPDERTSLRHSPAPVGSARQKPATPARAIPTSANHERQGLNHGSSDLQYGSFVHTPPNHDTGAPLDRKATFELPGPAMRVPSHQSDASPQPASAQDDQPMRQALQRSASMIADAPRSSGPPPTEHENTPSSLRLPHSATIGSGYNASPRGGLRRLFSNASPLNRSGTNPEYGLQGLAIDLVRQKEKEFFDFLDSELEKVEAFYKLKEDQAGERLSLLKDQLHEMRNRRTQELHVQKQQAEIDFLNGGHGDSDGPQKGPLGWIDPVKSKIFRPGPNSKALSKMAQTPVMRPEGSDAGRDYIRRPHEHDVPYRTAKRKLKLALQEFYRGLELLKSYALLNRTAFRKLNKKYDKAVNARPQYRYMNEKVSKSWFVNSDAVDGHIKAVEDLYARYFERGNHKLAAGKLRSLSRRPGDESGSAFRCGILLGTGLVFAIQGVVFGGQLLFDEDPEVRSRTSYLLQIYGGYFLMLLLFCMFCLNCAIWTRNKINYPFIFEFDTRHNLDWRQLAEFPSLFTFIFGVFIWLNFSEYGTNEVYEYYPVVLIAISVFIIFLPAPIFMARSRRWFAYAHVSCLAPLAATDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPY3</accession>
    <name>A0AAD8UPY3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_611133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367861.1">
        <property type="nucleotide sequence ID" value="XM_060507644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPY3"/>
    <dbReference type="GeneID" id="85391543"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="165" mass="18999" checksum="92DA0446802BE24D" modified="2024-05-29" version="1">MFLKPPSFNLTANVLLLLLLIFSPMFTQRALRVERFRSLDFSLKFLLITPSKPVNAMRLPNLDHVRDAMSNYVSRCLFCFFSNSLSRSPVTPTTMVHHSMFSPGVSFWLFIQFYFITAVLIQISITGSQHVQHESLSLAGWFPPCHRGRSRPRTSWGEGRLQCCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQE7</accession>
    <name>A0AAD8UQE7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_572127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367633.1">
        <property type="nucleotide sequence ID" value="XM_060504471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQE7"/>
    <dbReference type="GeneID" id="85388370"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56392" checksum="BAB92F63CA66B572" modified="2024-05-29" version="1">MLDENLPTFHFRPSSDNPQNTILYFTHQGSDPVPNYVLKRADPANPVARNKYAAALTDIASQQIIYAEVLVEPEWTQPTLSAAEVRVQNGTPAPPQPILPDQVTLQLYNPDSQVVIKMKSGSWGKSDSWEFEMPEQSFRAPSASLLDRSSDDPPISDTVPKVVFRWKRDGRLSKDMTCYMVGKSVAGKKSKEPDITVAMFKDTKHESAVTIYEPNLQRVDVEDRKGLDIVLLLGAEVLRDLFLNPRQNVFNLTATPPPTTGRRKNSKPPPVSMAPAPPTTAMSGAIGNKPASPPAQTMNNGPPRPNARQQWEIDNETKRLQAMVAQEERQARERERRDAEEAKRIKKMLDKEEADRRRKEAEIEAETERLRRLYGVPPSQSNPNLPPRHQPPPGTTPGSWHVAPAQPPRPNSAGPYNGPPGTSAYRPQVRFAQPPPTMSGGASSQPQQQSQSQSQQAGRGKLPNLMSGLLQGPYANPAASVSNFFHRDRSEEEEKKRKVAKKRSVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USA7</accession>
    <name>A0AAD8USA7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_264210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366441.1">
        <property type="nucleotide sequence ID" value="XM_060502017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USA7"/>
    <dbReference type="GeneID" id="85385916"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000343">
        <property type="entry name" value="C2H2 transcription factor (AmdX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000576">
        <property type="entry name" value="C2H2 transcription factor (AmdX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF13">
        <property type="entry name" value="RESPIRATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042217651" evidence="9">
        <location>
            <begin position="19"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="909"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="930"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1145" mass="124918" checksum="D194F7B6F1091AB8" modified="2024-05-29" version="1">MILIVADNVLAIILVASTITVNTKTPANFPPPKTDKPRPHVCATCQRSFARLEHLKRHERSHTKEKPFECPECTRCFARRDLLLRHQQKLHQTTTPSSRPRNRRESASSAAPGARARKNSVAGPNAAAAANAAAASMRPRANTISHVDGNAMQMIAAANAQVARGMPPGTHSRHPSLAGLPVHNMDFAGMSAAMGHRGMSHGLPKLETHGINNMDFSGLRTAPPMAVFNPDFDFEGLLFGPGSTINPNALHYNDSPQSMAMDQASPFPHGLAGDMSTTQLDDSFDWLTGFEHQMSFQGADNAVDGSSPSAISTTSQSGISDVMVDGSNHHPAPAGTSSMWQPAVMGPPQVPNPFAMDLNGSVFPDLLNGAPVSPQPAAQKMNDAYFSTPPPSLSSLSPSMVSGLNTQNLNQALNFNGGPETPSSLNGGNHGVSPVSTITETTRGAIVGALSQCSPFGGRRYSFATPSSPMSPGFQNTANSVPDHVKNLPSTQDLQRYVGAYLRYFHPHLPFLHIPTLTFEMPPTAANRSNTVGGSGCLILSMSAIGALYEMDHVQSRELFEMAKKMIQLYLEERRKADVRKADLRRAPASDPTSHNQESSVHTPVWLVQAMLLNVVYGHNCGDKTASDIASTHCAALVSLAQAADLLRPIRVESTEAHDTHMHDDTWSGLRSDSEEHIEWLRWKVMEERKRTLYVVFILSSLLVAAYNHTPALTNSEILLDLPCDEDFFAAESATAFAAKGGVHAANHNRMTFHEALGDLLRSNEKQQKQLAFQNGQQVFGQGSMNDLKSDLKPSTFGCLILINALHNYIWETRQRHHNKVWTNEETEKMHRHIEPALKAWQAAWASNPNHSLERPNPFGLGPLSADAIPLLDLAYVRLFVNLARSKEKFWQRDWDAMADELSRGSEIVQHAEHSPASNPESTGTDHSDNSVSSSVFVESPATQSSSSPEFSAVKFPQAQAAPNRSTSRREKHLRKAAFYAADSLAMSDKLGVTFADFSSRELPLQSAMCAFDCAQVLAEWVATLQDRVGRYLGILGQDDVDLSQVPAIMLLEEEDVKLLGKVQEVLASAEMKMNFELVQGNIAGVDTRMQMDDHAGHAAKILRVTAYMLDKAAVWPVTHLMARCLETHATHMRARAEKSVIPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USN5</accession>
    <name>A0AAD8USN5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-tRNA hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_649313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367755.1">
        <property type="nucleotide sequence ID" value="XM_060510260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USN5"/>
    <dbReference type="GeneID" id="85394159"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221929" description="Peptidyl-tRNA hydrolase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="29581" checksum="5851A53028436647" modified="2024-05-29" version="1">MRVSATTLLALPLLATAAESPFEQYKAQFQNFLSSFGASAPSAEKAATPEAAVPDATAVDKKISVLTVDNWKDVLYEPVKADATTPEEWWVLITGRNKTCFGHCDKIETAFNESTIKFAKLPESPHLGLLDCDDQPVLCNAWSAGTASIWSIGLLPPGADVDVYRKRLNITTTTSDDIVDLWKAQSKEEWILTDNIFHPFNSWIAKNNLSVPVGYVFWAFNLVPNWLFMILVSFGSRTLMNRRMGNTFDNRAAAAAGGAPPAAAAPAGGVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTY6</accession>
    <name>A0AAD8UTY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_608150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368837.1">
        <property type="nucleotide sequence ID" value="XM_060507463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTY6"/>
    <dbReference type="GeneID" id="85391362"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47941">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="385"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="721"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="629"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="653"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="92203" checksum="E32741F9F46CC3B2" modified="2024-05-29" version="1">MSHSLAGRQCLRHIRQRGNLAANNYIQTSFQARPNTSSALGPSIERPFRIRKIKRLVESGSRSAPTPIGAPINAEASRRRTEFASKNIDTWSPQNGGERKKKYEFTSGNADTWISELVKERKRRYLEYGYLRHRLTKKELKDFENWKNDCKRLYGFASFGEGYKVPKVLSWIQDRQAVEDAIEQWPTWTEEQKKTKWRKLMFSALWSCPDRAAAILEITTRDIKPPGYAISDAIHFLAKWQSQLSKPEFTEQRRHLCNVVVTVFERLPAAYIPLRQNTIYMLTHEAELPILIALYDCWRGKDVQLHSNTLQNMARRLAVSPLHKNLALQMAIESIPDQGVDLDSGLWASLCTSILSLKRGQIKVDDGFSAADAFVTLIEHGFAPNMVHYTAVIRSLCLTDQNEVAEEVFQVMQRHNFEPDMIMWSTLLDGGKRALSPSSIESAVIGAVEGNEIDVPFFNDLLMCLLHFCKWTPGVMPAFGPMLHFYSKVFHLAPLQALLPVDLSMYLEGQEGLQMPADWELARQLFPALDRAMSAVYEKMEPTSATLSIMFLAYVRSMSQPINLISLYAYLRQEILKGSPSATKLVQEKGSFMYDVLIKALCKHPGMLRAALDIVGDMLKYTLEERSRAADAAKQSSKGRRDSRRTEVKETEVQQTGAQDSQAQESKVQESDAKETEVAPAPLHPAPSVFTWSILLHGFSKEKGSGERILAQMRQHGVEPNLVTWNTLIAGYARAQDVNKTVLSLQRLEASGHEADDFTLRAFSRLVNRELALRKMEDALTRRATRDEIKRLEEQRMAEMPLGPEVKGRLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV63</accession>
    <name>A0AAD8UV63_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-loop-helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_125676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368433.1">
        <property type="nucleotide sequence ID" value="XM_060501180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV63"/>
    <dbReference type="GeneID" id="85385079"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="366"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="433"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="52757" checksum="F6333147A4A196AB" modified="2024-05-29" version="1">MDPNFLKNLDYFAVPNNQTTNSAEQTAESSATGAARNAPDNSLWESLGGDPANSESTSNGPSGSLPSFAQASPASTNYGLGSMPAQMQFNHGGQQRNPGLPSRAAPNQDPRRRDGHARKRTKVDSEAAALESVDYWIQFDDDEEQKLGGSFEIDFSRRSNPTPNYRPRPAANRLNPMSTTPGLGAGLYTNPVFKPEDFMDDAALDNALSDDEDFLESMNLGDQLGKIDSQPPQEVPPREGLYSTPLSWEKPAPGLRMNPLFGMGGMGAMALNTGRSSTSLGSGMGFGVGADLGPEFASLENFDATMASGSMNDPANDPEQSAPHKGKQKEKAPIKEEPGTQRPQVSRSTTNATGVSEKSKDKVKAGDRTAHNDIERKYRTNLKDRISELRDAVPSLRSIPEEGGGEDAEVDSQSQRGPKVSKGTVLTKATEYIHYLERRNKAIMREHQELARRLQAFEQLLSAQARQPFPMPNYSRTLFDPRGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXQ9</accession>
    <name>A0AAD8UXQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_717097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368570.1">
        <property type="nucleotide sequence ID" value="XM_060511910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXQ9"/>
    <dbReference type="GeneID" id="85395808"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="27133" checksum="0609DC7579605924" modified="2024-05-29" version="1">MNELPIQPSGIFWQDDFITAEHEEKLIHIFRNELSWPDRSGRLSLHYGYTFDYKTFGVDPNIPFNPFPDWLEPLIPIREGRPPDQVCLQHYPPGAGIPPHVDTHSAYDQLYALSLGSPVMMQFALPPDEGEEGRIVEVDLTPRSMLQMSGDSRLHWKHGIRKRKTDTLPDGTVRKRGDRWSITYRWIREPANCGCGNAKLCDTAQRELGIEKEYRWKKGDEDIAAAEEEKTETKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7S6</accession>
    <name>A0AAD8X7S6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SEP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000246">
        <property type="protein sequence ID" value="KAK1705180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357564.1">
        <property type="nucleotide sequence ID" value="XM_060515064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7S6"/>
    <dbReference type="GeneID" id="85398962"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.210:FF:000002">
        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="3">
        <location>
            <begin position="224"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="340"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1705180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="421" mass="44503" checksum="6FAE114FC8D0D60F" modified="2024-05-29" version="1">MSGSSNSASRNNILRDFKSLTGMPEARCTEYLESANWDIGLAAQAYYADHDSGEEEIEPVAQAQASAPAPAEYTGPRTLDGRPAPESAGRASTVKKAAPKKKGLATLSSIGGGHTHDDDDDEDDEDDDDRGRGDLFAGGEKSGLAVQDPSQEGGGAKKIISDILAKAKANASRPETASPAGPSRSGAFRGSGTTLGGEGSESRSIPDPDAQEGASGSAGATGEAQERTLHLWQDGFSIDDGELHRFDDPENAMDLNMIRAGRAPLHLMNVRYDQPVDVKLHQHQENYHPLPKTYKPFGGEGRRLGSPVPGEGSSSSTTAAPAASVSASASSTGPQQAVDESQPTLTLRIQLPNGTRLPARFNTTNTVNDVYEFVQRASADTRTRSWVLATTFPNKDHTDRSLVLGEMSEFKKGGTAVVKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8B2</accession>
    <name>A0AAD8X8B2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_172720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358164.1">
        <property type="nucleotide sequence ID" value="XM_060501476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8B2"/>
    <dbReference type="GeneID" id="85385375"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000281">
        <property type="entry name" value="Uncharacterized oxidoreductase YIR035C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF8">
        <property type="entry name" value="BENZIL REDUCTASE ((S)-BENZOIN FORMING) IRC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1707948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="253" mass="26883" checksum="DBAEF89A9794F221" modified="2024-05-29" version="1">MASKVIIVTGASRGIGLAIAQHLIQGSHKVVLAARSKDQLEALKVAHPGQVEYVAGDLGDLKTIPKIAEAAVKAFGKIDGLVINHGVLEPVTRLADSSIEEWKKAYDINVFSGLALVQASLPELRKSKGCVLWVSSGAATGAYAAWGAYGTSKAAMNHLSAHLAVEEPDITSIALSPGRVDTAMQKVIRDTGAGHMADKDHTSFVSAFDKGELFKPEQPGSVMARFVVKPQHDLSGKYFKWQAGELSAYHDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8S5</accession>
    <name>A0AAD8X8S5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_156752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358252.1">
        <property type="nucleotide sequence ID" value="XM_060501368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8S5"/>
    <dbReference type="GeneID" id="85385267"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF52">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1708220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="335" mass="35115" checksum="D064857CE4C029AA" modified="2024-05-29" version="1">MSPSANGGPDSHNGNGTQHGARPALTPGLYVPTVAFFRSDDSVDVETTHSHAVRLAKAGVAGLVTHGSNGEAVHLDHDERQLINRTTRAALDSVGKTELPLIVGCGAQSTRETIQLCKEAGSSGGDYALVLPPAYYGGLLTTDLILQHFREVADASPVPLLIYNYPGACSGLDLNSDTIINLSSHPNIVGVKLTCGNTGKLARIAAATAPKKGDNNTTPFRTFGGSVDFTLQTLVVGGHGIIGGTGNIAPLACVKLMQLWDEGKLEEARALQAVVARGDWTAIQGGFVSVKAALQEYYSYGGLPRKPCTLLEGESLTKQIDGFSELVEAEKALQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Z1</accession>
    <name>A0AAD8X8Z1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_758778</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000266">
        <property type="protein sequence ID" value="KAK1704310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357417.1">
        <property type="nucleotide sequence ID" value="XM_060515089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Z1"/>
    <dbReference type="GeneID" id="85398987"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041766760" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="23"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="162"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1704310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="376" mass="41831" checksum="BA065C676A268017" modified="2024-05-29" version="1">MRLTPLLAALAACSAAGSFVEPRDPNKLFTLEIAPGETVTVTEEEKWEMMDKRVHFFDITEWSDVPAVASSADFKLLAALPFPTEMNQTCHVNALIPKLNKDNMRAHLERFSSFHNRYYLSKTGVESAEWLYGQISAVLDVAGHPTANIRYVRHTAWSQPSIIVTIPGRNQRTVVLGGHLDSVISGDRGAGRAPGADDNGSGSVMILEVLRVLLSDPKIASGDILNTLEFHWYGAEEAGLLGSQDIFTQYRASSRQVVSMLQQDMVGYVGRDGVERFGVVTDWVDLDQVAFMKRVIDTYTDIPYEETVCGYACSDHASANRNGYPSSFIFETPFGNHNPYIHSPNDTMEYVSFDHVLQHAKMATGYVYELAYWPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9G0</accession>
    <name>A0AAD8X9G0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_96138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359424.1">
        <property type="nucleotide sequence ID" value="XM_060516032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9G0"/>
    <dbReference type="GeneID" id="85399930"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042170563" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13439" checksum="E59B44DAF5320428" modified="2024-05-29" version="1">MFLICLLFFCTKRQLPGMTFFVVTVPKSHLEKRTQCPPVVGDDAMPPYSHSFPPHPHPPKKGQHMLGGLAMKKERRKQWTQWSRYSFFTWPRPVLFLFHDRRYPHYNRNKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA22</accession>
    <name>A0AAD8XA22_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="9">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_645577</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000345">
        <property type="protein sequence ID" value="KAK1701675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357039.1">
        <property type="nucleotide sequence ID" value="XM_060509861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA22"/>
    <dbReference type="GeneID" id="85393760"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000721">
        <property type="term" value="F:(R,R)-butanediol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019568">
        <property type="term" value="P:arabinose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034079">
        <property type="term" value="P:butanediol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08233">
        <property type="entry name" value="butanediol_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF23">
        <property type="entry name" value="(R,R)-BUTANEDIOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="13">
        <location>
            <begin position="8"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1701675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="357" mass="37590" checksum="75E50E3D10DF9657" modified="2024-05-29" version="1">MRAARYYGKEDIRIEQVPEPSCGPNQIKIAPAFVGICGTDLHEYLGGPNFCPSSKHPVTGDQIPVTLGHEFSGIIKEIGSDVKQEHLKIGLPCAVQPTIYCGKCAACKAGAENACHTGGFIGLSGGGGGLSEAVSVPADQVFPLPEGIPLELGALVEPLSVAWHAVSATTVTPESNVLVMGGGPIGLAAVLCLKAKGVTNIMVAEIATARQRFAKEFGAAHIIDPKSQDVMEEVMNITGGIGADVTLDCAGVPASVKAACMAVKTRGTVVNVAIWEKEIPFNPNWVTWRESSYKSVLGYQKKDYQAVIENLRTGALKPASMITRKIPLDDLVEHGIKALITDKDNQVKVLVDVGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAH3</accession>
    <name>A0AAD8XAH3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TAP-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_590692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359141.1">
        <property type="nucleotide sequence ID" value="XM_060506358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAH3"/>
    <dbReference type="GeneID" id="85390257"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="125"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="473"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1711588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="590" mass="65191" checksum="E469443517C1E1C9" modified="2024-05-29" version="1">MDSKFSSGFPWPKEATRPGSKCRTAVTAALSVLTVTALIRGNFFRGPWSLAGRGNTVKQAADSEWTWSSIKPSRTLEWHSCFENGEYDCARLDVPMDWQEPSDDHRVVLAITRIRATDKSDYRGPVIFNPGGPGGSGVWSLKNHGKMLQEIIGANHDLISFDPRGVGASIPRIQCWSTPQQRQNWGLQDPGVLDSHEGIVGELFARATAYSQACESAMKASGILEHSSTTPTARDMLEIVYQTGYSKLKYWGFSYGTILGGVFAAMYPDKVERLVSDGNVDYREWFNSEHVNFIRDTDKVLFAFYEFCYQAGPEKCAFHGPTSEAIMGRFVDLLNALKRHPVIVPADPEEGPEVPVLVTYSKVMRLLSTTLYQPLEQFGNFANIIAALEKKDGRPYYRRYNPSKPAPAPACAPQPVSPFEPPPGIVEGTGDAFPVIMCADHPAVSNMTLEEIQRETDGILELSPGTGATEVPYQMTCNQRTTRPRWRFGGPFEGKTSHPILFIANQADNITPLVSARNNSVGFPGSRLLIQNSFGHTTLAAPSECTRGYIRAYFQNGTLPEPDTKCEGDSHPFGPFAEAGVQFYQPTLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB09</accession>
    <name>A0AAD8XB09_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_80783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359711.1">
        <property type="nucleotide sequence ID" value="XM_060515935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB09"/>
    <dbReference type="GeneID" id="85399833"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35528" checksum="DC8C6F26DA3C9BBE" modified="2024-05-29" version="1">MFCLLFIKEECLACRVHNPDKALHNTAVSKTPCPFFLTPFSSNSSAPDFAMAVPSAIQQYPKNDTLAKAWDMLQHTLEIAFGPQSWHLVTEVKLVADFPTNSAIWLTRAAEMRALNGLANAQFIGNRDPQLHPRLDSLNDNICLEVDPNMMWKERKYDLIHSRVIEYIENWPEYLRNVQTCLAPAGMLNIEVVEMIPFTDEGSLPETSPLLQLSRILYEPSETSKIGRVSSNIGRDLNRIGIQSKLVQYRLPVEDCQDEGEIPVGDWLVSTMVKFIEAHVAIAREGPEQPQLDDRLVEAAKLEISNPAFRAYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBC6</accession>
    <name>A0AAD8XBC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361012.1">
        <property type="nucleotide sequence ID" value="XM_060514636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBC6"/>
    <dbReference type="GeneID" id="85398534"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF2">
        <property type="entry name" value="PHOSPHORIC MONOESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="29033" checksum="DEABF3641377FAF7" modified="2024-05-29" version="1">MGSHVSETPALATNPNFIFFTDFDGTITLEDSNDFLTDNVGYGYENRRAGNLLVLEGKKHFRDSFQEMMDSVKLPFDQCIEYLKKNVKLDPVFKEFYTWCRANNVPVVIISGGMRPIIRALLVQWLGEEEVDGHIQIVSNQVAPREGKASINEEGGWQIVYHDDSIHGHDKSIELRKYSSLPERPVMFYAGDGVSDLSAARETDLLFAKRDKDLVAYCEKEGISFVTFNDFSDILSTVKQIVEGKLSVKDAARGRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBR4</accession>
    <name>A0AAD8XBR4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_766623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358793.1">
        <property type="nucleotide sequence ID" value="XM_060515271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBR4"/>
    <dbReference type="GeneID" id="85399169"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF15">
        <property type="entry name" value="EXTRACELLULAR SERINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042260248" evidence="2">
        <location>
            <begin position="19"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="22758" checksum="BA1AC50ECBFBCD83" modified="2024-05-29" version="1">MHTSSLLATLLPAAGALAQYGYGAQESSTNTASAAAASSSSIAGVHVVKVGDGGLTFEPNSVTAAVGDVVEFHFYPRAHSVAQSAFDSPCQPLTNGSTTGFFSGPVQVASGVGSEVFTVEVKDTNPKWFYCATGQHCQGGMVGVINAPASGQRTIEQYAQAAAAAQSNVAPSATGGGTLGSAATGSPSSASSSPSASSSSQPSAGIEARGDVRWGLLSLGMAAAGVVGGLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCN7</accession>
    <name>A0AAD8XCN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_676089</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362437.1">
        <property type="nucleotide sequence ID" value="XM_060511157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCN7"/>
    <dbReference type="GeneID" id="85395056"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF4">
        <property type="entry name" value="CYTOCHROME P450 98A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="489" mass="55425" checksum="2D4B4180BB4E404D" modified="2024-05-29" version="1">MPPGPFPYPIVGNIGRVPAAKPYLIFEKWSKEYDSPLITIWTGNRPTVVVNDCWAASDLMDKRAQIYSSRPHSYLADAFDETENNQTSLVYGDKWRLHRRITHTMVGSQAVRGYQTFQANESKILVRDIMETQQFVSAIERYACSVAAIIGWGRRVRSMDDDLANLALSFVQTGAGFSTPAQYLVEAYPWISKLPKRIYPFPSMIWEEGQRLLKYFYALTVEGAQLEQDSFSKRLMQDQDKNNLSPKEIASLTGNLIGGGVDTTTTSIIVFIFAMCAFPRVQQKAQEEIDRVLAGEPPTWADEDSLPYCKALLTEIFRWRAAIALGGPPHSPVQDDTYKGMFIPRGTSIIGNLWAIHRNPRDYPSPDEVRPERFLDERQPNPSKRGIFTFGWGRRLCSGQPLAEQGIWFTIVGLLWSFRMRSTDEHGNSKELDIFAFNDSPAPRPLPFTVEFKPRTSTTKGIIQAAALKAEDELRKYEVNSNVAIENFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD48</accession>
    <name>A0AAD8XD48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_53937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360353.1">
        <property type="nucleotide sequence ID" value="XM_060503389.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="750"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1153"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="923"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="953"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1497" mass="163030" checksum="29EC3C0F5592A59A" modified="2024-05-29" version="1">MATRRTALGLPSRPDEQIRARRAAAAGYMEQSEDLPSTPRRIRREGENIRIAIQQPVQTKPAPMPPTASSRRPSIPMPSTRPPLTHQTQSWSSNSTAPERPSHAPTMSGSSTSGQSQSSVAKPKRNVLRRKQSSVTQKTPSLRHDSNTDSTRGSSSSSAPRSRSSLEPAPYHLDRGMTESPTEIRIAHVIDLPKTQAQPVTIYPELDRYREIYGRPSTSSEGSSVDFLHRLATHDLPPPTPVFSGTSSQLSAFSGSPSTRFSESTSPGPYSRDTTPTSMSSQSPGLGVPMRLPVPRVRQVSPAVTRPPVARRRAGSIPNEMEAFSADPQGLAAVRESLTSSSSNSTVREGDRKESKKKKRLSPLPPSLPPRKSSQKFTKDQDNEESPSKASREPAVPVMIAPSTIQSPPRRTPAASPRATPPARPSRDNTPDLQSQLFGPLPIIHSNLSSSSLLGDRRGPELQPLSRSTTPLSYPDNPQQTSRLPVGREATPAPRSANAVDTKKKNERTVTRTPSPGTSAFSRFPFFGRRSRTAPEVPQVEKKDKPVRKGPAAGTGHEGYGRLGGLRRRSGSSATNLARPSLGPGSSQDSLSSNQPTDPFLLERMNPVIISGGGLVDNRNNSVDLVRSESYQSLGYASEVSTTSSIGRSLAPSAIPRGGPHPSLSRRRPSDSSDSEAVTMKPTLAFRRSVQRLRSSPDQSPLKLPQPINTTGITSPSINSHDTSILTDDSQFEMHREVIRGRIAAATATPPKKLTKRTRSPRKWNLFSRSQSQPNTKKSEKDAVPVAATVKVVQHKPAAFYTLMDGSEQEDFGTPDVEEILREAEVFDLPSPPPVLKERRTSSASQTNRRESLSRLLQPTKSSQARRNSATAKSTSIPAIRSMKPTHTPQSSVSKPAEPRPSRLPQVGRIPKVVTSRPEHTSSRSFSRPFNRSSMQMPPQAASFNPDFVASGATPTPELSTPELSRGESTATSDKTNSDPRSSLVPIKTPEMIQIGREFLAFSPRKNSECTTSTDSSSLGMYTLADAMAYVPDPNAPLVEDEIWDEYNDLIGDVPPSATSSKGAPFHLETHGSRMSKRSLKPLESPTIAPLAKTLEKNVEVEAGATTSSVYSADMTERLKAAFALKPEGEILVPVGEIPARVIDRESTELARKATAASQRSSGSSRKSRQSDCSCKSSEDESPLSQVNLRVGSMTVSKWLSFGHVLFSPARDQLLDVVGSLKRHSILVVDGLGNDDWSFYAAETYPAATFFNLSPRAPLPEEHKNSSSFPLSPPNHHQIQYLSQMDKFPFGAESFTSVVFRFPAAAPESHYRNIVSEARRVLKPGGYLELSILDVDLNNMGNRGRRTVRRLKERIHVNNSEVSIGSSSDLILRLLGRKGFSDVKNCRVGVPVASVVTRSESGSKKPPVAGTQKAKEVRSLAEMMNEDGDSADENITKMVAKVGRWWYSRCYESAAGTISKSIWSDRALLSECEELRTSFKLMVCYARVPDRARTASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDK2</accession>
    <name>A0AAD8XDK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rhamnogalacturonan I lyase beta-sheet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_753740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363292.1">
        <property type="nucleotide sequence ID" value="XM_060514388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDK2"/>
    <dbReference type="GeneID" id="85398286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041624">
        <property type="entry name" value="RGI_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034641">
        <property type="entry name" value="RGL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049366">
        <property type="entry name" value="RGL11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43118">
        <property type="entry name" value="RHAMNOGALACTURONAN LYASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43118:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN LYASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18370">
        <property type="entry name" value="RGI_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21348">
        <property type="entry name" value="RGL11_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079565" description="Rhamnogalacturonan I lyase beta-sheet domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan I lyase beta-sheet" evidence="2">
        <location>
            <begin position="24"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase family 11 C-terminal" evidence="3">
        <location>
            <begin position="139"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase family 11 C-terminal" evidence="3">
        <location>
            <begin position="274"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="65813" checksum="2FF5E812DF264AED" modified="2024-05-29" version="1">MKFLNLLSASFALSSAFLAQAARPLESLGRGVVAVRASDEDILVTWRLLGLDPSGIGFNVYRDMGTSPTKLNDKVLTGGTNFLDSTANPEEVNTYFVRPVIGGKEQDASGSFSLPARKAVEPVVRVPIRSGGAVKFVWVGDLDGDGEWDYVLDRQTSPQTIEAYTGNGTFLWEINLGPNSENQNNIEPGSSTIDVGHWDGVTVFDFDSDGRAEVAIRIANGVVFGDGKTFDDGETDNHQSMAILDGRTGALRASAPVPTDYIDDGPLAARLGAGFLDGETPHLVAYMKNRIGSGDFNLMYVTWTFDGTSLKQKWKWNRGDKNFPDGHNTRIIDLDGDGKDEVLEIGFALNGDGTERYTLGDQGIIHGDRFHLAKIDPNREGLQGYGVQQRNPDLIYEYYYDGSSGKIIWKHVGDNVTDVARGMLGDIDPTHPGMEVWSFSGVYNAKKNELTELDTELAPWPHLGLWWDGDELLELFNDGKFEKWDWEKPSASSSLPRILRVSDFGGVTAGRYPNFIGDILGDWREEVIVTNAAADELLIFTTDKPSDTRLYTLAHNPAYRNAMTLKGYMQSHHVDYFLGNDMKMPPQPNIRYTVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDP5</accession>
    <name>A0AAD8XDP5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_417479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362546.1">
        <property type="nucleotide sequence ID" value="XM_060502961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDP5"/>
    <dbReference type="GeneID" id="85386860"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF219">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="600" mass="67298" checksum="04C2F825F261A3BC" modified="2024-05-29" version="1">MSWLFSRSYPERKAVDVDGKTFDYVIVGGGTAACALASRLSEDPSTSVLVICKGKVKDNWLDRIPIVGNASDGKGPQIETFWSEPDERWTGCKTRTFNTQALGGATRVNGLMLTRGAPGNYNQWAALGNDEWSWEKCEPYFKKIENAACHPNAPYRGHEGPLYLRQNPLNFPIDQYIQKAAGDMNLPVENDGNDPNAPAMGLFTTDIMIDKFGYRHSSLAAYLPKSTVDEREDRLTLCTGVVATKLQTSDDRTEVTGVYILDHLDKSPARQCFVRAKREVIICCGTHFSPQLLMLSGIGPKEHLQKHNIPLIRDMPGVGADLQDHITFGIAFRTRLIDSYLRLFSPLIGIWHFILFLLFKTGLLATSGTRLCAWFHTSTIDETTMTVRHHGNDIDEKHDNTDALNPENVPDIELLFTNASYDYEKGKGFCAFQTTLVQPFSRGRIELASSDPLAHPKVFHHYITDPRDWAAARKAARVSMNFVERFRQTEYPFNATWHLAPGVKAGTVEGGWRDVTDEQIDAYIRERLVNIYHATSTCRMGNVEDDGVVGQDLKVHGFRNLRVADASVFPKVTSAHTVAPTYMVAERCADFIKRDWAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEM4</accession>
    <name>A0AAD8XEM4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_651716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364989.1">
        <property type="nucleotide sequence ID" value="XM_060510475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEM4"/>
    <dbReference type="GeneID" id="85394374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="24015" checksum="68BA4A2408764697" modified="2024-05-29" version="1">MTFAIENAFALAILGEHNPETSTTKDLILRTDLAFWRVSSRLLEGNTSLPSAEADIFEGTFTLPMLGKRAISDLDWSTLVATVLEVYLSIRERLIRGECVLPSPQSTMRASRLDPSVTVLFGTGPTFPAAESDVGEFPDNILDGEYEEYDEDDREMGSADSGSTKKGKRNDEESKKGVRTSTPGPPMELHPRQDICARTSRNTRQGQPLETDNCGEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XET2</accession>
    <name>A0AAD8XET2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362138.1">
        <property type="nucleotide sequence ID" value="XM_060512906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XET2"/>
    <dbReference type="GeneID" id="85396804"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="20158" checksum="286989A96A3D1589" modified="2024-05-29" version="1">MGVEKRIKGSSMPPTNNGSIGCDIAILAAVKTMEQQDVRPANPSLPLFSETNDQVKDRNSEVIEELSTNLDDISNAQPNPYNPSIMAGTADEKDPQQPNQTEPLASTRKGKVNSKPGPLSEAERTAARLEIARVLEGVPIEETTFILVNWVLELFMDMGIDLSVGFKEFIAEKLTDNNQLFADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEZ7</accession>
    <name>A0AAD8XEZ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_793284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363956.1">
        <property type="nucleotide sequence ID" value="XM_060515777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEZ7"/>
    <dbReference type="GeneID" id="85399675"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="214" mass="25288" checksum="59A7CB5C7FFFAC94" modified="2024-05-29" version="1">MARLNGCYHYHVRNQQYHCHDIVFILDDDLSDNHRHVLDNVVTDVNLLGLLVIFVLLLDDLPNDIDLNNLNNKKHPNVPSQYPSSRSPRTSTANDHHDVKVSLHLQYPGAGSAGREPPQLYEFEFIFDHLLYFDHVFSFVEFGYVGYWHHNLKHFSIIVGVIFNIVPRIIKQYHDFELFYLDYTNVKRSQQRTFPHKSTAFPDIWHFVPRFNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF55</accession>
    <name>A0AAD8XF55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear pore complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_632558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361300.1">
        <property type="nucleotide sequence ID" value="XM_060508979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF55"/>
    <dbReference type="GeneID" id="85392878"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030474">
        <property type="term" value="P:spindle pole body duplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012578">
        <property type="entry name" value="Nucl_pore_cmplx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28003:SF1">
        <property type="entry name" value="NUCLEOPORIN POM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08058">
        <property type="entry name" value="NPCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="28885" checksum="90D3470507F2C69B" modified="2024-05-29" version="1">MSPSASRAAVSTPVKSTPQKPTPIVDSPGTWRHPRLNEITRRRNATTFSEKNVRRIALNIGFLLSLWLSQIFSRSYIPAQWFSSSLRSYLGWAYYLIQLIPLVNIGMAMLPLLRSADDLSDIPLTPAQRQLLGLPPSSAAATPDAVYSTPPRYSRTPSLAGSPASNRSFSGSPLSGRGSPALGGSFNGNGQSYSPSPLHNSPSKFSASLNSNRRSSFGSSTNLGASTASSLFPDPGTPSPSTGKRTSVGLNNKWLYERGRRSSGGTWMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFX0</accession>
    <name>A0AAD8XFX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ClpP/crotonase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_741097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364871.1">
        <property type="nucleotide sequence ID" value="XM_060513082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFX0"/>
    <dbReference type="GeneID" id="85396980"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43459:SF1">
        <property type="entry name" value="EG:BACN32G11.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43459">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042066359" evidence="1">
        <location>
            <begin position="23"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="28581" checksum="77BFE22F38FC7EC1" modified="2024-05-29" version="1">MMHSFIFSGLALAATLVRPVYSIDLPNYTGLKTTQNGSVLTVTFHNPSSPINLWNLDTQDDLTDLVSRLQGNNETKVVIFNSDLHQVTIGAVEGRARGAGNEFLVSLDMRFATKGESLFGQPEVGSGLFPGGGGSQFLPGLIGRGRAMEYVLSSNDINAEDAAQIGWINKAFDTSGEMYGYIDKLAQRFSWFPLSALSGGKKTINRASAPSLEQVIEDTKDFFQQQLDPEAQAIAKRSALLSRNVSAVDLELNLPETIARLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG02</accession>
    <name>A0AAD8XG02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucan 1,3-beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362170.1">
        <property type="nucleotide sequence ID" value="XM_060514494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG02"/>
    <dbReference type="GeneID" id="85398392"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23668">
        <property type="entry name" value="GH55_beta13glucanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000023">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000026">
        <property type="entry name" value="Exo-beta-1,3-glucanase Exg0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051801">
        <property type="entry name" value="GH28_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="RHGA/B-epi-like_pectate_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31339">
        <property type="entry name" value="PECTIN LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31339:SF9">
        <property type="entry name" value="PLASMIN AND FIBRONECTIN-BINDING PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pect-lyase_RHGA_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236887" evidence="1">
        <location>
            <begin position="24"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase A/B/Epimerase-like pectate lyase" evidence="2">
        <location>
            <begin position="417"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="786" mass="84003" checksum="F5718CA3C34FF04A" modified="2024-05-29" version="1">MGFSTVFTAAVLALRLFSADVLAAPAPAPVPQAATPDAAAGFWVASIERRGVSAFGDANYKIFRNVKDFGAKGDGSTDDTVAIQAAMDEGNRCGFGCDSQTTTPALVYFPAGTYVVSKPIVMKYYTHMVGDATQLPTIKAAASFTGMAVIDANPYDDQGNNAHTNQNNFWKLVRNFNIDLTGMPFTSGAGIHWQVAQATSLQNIVFNMRTDGGDANVQQGIFIDNGSGGFMTDLTFNGGKYGAFMGSQQFTTRNMTFNNCKTAVYMNWNWLWTFQDLKINNCGVGIDMSNGGASAQTVGSVLLLDSVISNTPVGVLTAYNPSSSSTNGSLILDNVDMTSNVPAAVQIVDTKATVLAGNQKIGSFVQGKTYTGTAGQGKAVQAAQDAIVKPAGLLASDGKVVTRSKPQYANVPASSFLSAKANGCKGDGKSDDTAAIQALFNKAGPNDIVYFDHGAYIISDTIEVPKDIKITGEVWPLLMANGAAFKDQANPKVMLRIGKTGDVGTFEMSDIIVQTQGPQAGAILMEYNIAGSTPGAAGLWDVHFRIGGSAGTQLQSDKCAKNPNVTTTANPECIGAYLLTHMTAESSGYFENTWWWVADHELDLPDRKAQINIYNGRGVLCEATKGTWFWGTASEHSVLYNYQFNNASNVYMAHIQTETAYFQGNPDAKTPFTVNNAILDPNFETFCTGQSDKCARTWGVRAINSKDILIYGAGLYSFFNNYDQVCVGENNCQDHMVSLENSEVKFFGLSTKAAINMVTVNGKGAALDTDNRNNFCATVAMFQAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG25</accession>
    <name>A0AAD8XG25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_618139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365992.1">
        <property type="nucleotide sequence ID" value="XM_060508060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG25"/>
    <dbReference type="GeneID" id="85391959"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="424" mass="47574" checksum="016161B4AD2FCC33" modified="2024-05-29" version="1">MDNASKDATSQPSPVSEVTQLAYMPDVVVLNMVDMLLNDDDISGYLESDEERSDVWTAASSEGRRSWGVQNAINLAKVSTRFYNIVSPAVFRHDIQHRFASSLLLSAKRNNLDGVSASLRHGANINQTDQSLMHIEEREIMEEHRFECLLLPVKTFLTALHWASLYGYKDLVHHLLKSGADVQHRADLGFYHYSARDPWEHESCLREYETDMEDPQRALFCATKAEYLNSMYRSSAQSQEPLPLPMGANPLFFALRGSFDSENRALWEVTSTTHLALGMKPFLADDTSGSRLEIVKALIKAGSSLVTREKDKVHALHQACAYRDVGVVRFLLKEVGVDSNTEDSKGDTPLHYMAANQHHPMYAPVESSHEPRRRTQEIVNLLIDRGADLVRQNIDGKTPTDCGLLLIHGNRVKGEVLGPLMLCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGH6</accession>
    <name>A0AAD8XGH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal L22e family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_719282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365456.1">
        <property type="nucleotide sequence ID" value="XM_060512162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGH6"/>
    <dbReference type="GeneID" id="85396060"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="128" mass="14547" checksum="1C98069A505BC763" modified="2024-05-29" version="1">MAPQAAIKRTGKGKNQKVTKKFIINASQPASDKIFDVAAFEKFLQDKIKVEGRVGNLGDQVQISQQGEGKIEIIAHNELSGRYLKYLTKKFLKKQQLRDWLRVVSTSKGVYELKFFNVVNDEADEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGY6</accession>
    <name>A0AAD8XGY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_279506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365966.1">
        <property type="nucleotide sequence ID" value="XM_060502122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGY6"/>
    <dbReference type="GeneID" id="85386021"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF5">
        <property type="entry name" value="DUF6590 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="45521" checksum="192FEF28C0B3FB55" modified="2024-05-29" version="1">MSSLRDEEAVDTNYLIRLFLDAPAEETPHVGASLIARLAEGTIAVFQDIQKTPIDEVKGNFETRSYLVSLGRSSDRLRLWSDGYGISSGGSDDLFEQSSRLRGARLEVLSSVELTLTERLVASTWGAGPLGKAQLPESFTTKVEQLRQLIQETEDIKAKSEPSTGSSSYYDDNIFQITADLETDTRSLMDLDALFPEPILDTGHMRQSLPSSLHKWEPHEHYYHIINNRFPKADDGLITSLGKANSERFLRGQEQRESSSREVLGPIPLHQIENSDAASSKFNDSGLGSSIPSSYAETIISYHGGEGTSIRLPSLPKSASNGSSFLCIACGLPTLAQTNSAWKRHLFNDLRPWQCLEPSCGHKGIFSTRGDWVSHLALDHFGPEWKGAECPLCRNDTGSGKITILKHFGGHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHB3</accession>
    <name>A0AAD8XHB3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580984</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363385.1">
        <property type="nucleotide sequence ID" value="XM_060505408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHB3"/>
    <dbReference type="GeneID" id="85389307"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF2">
        <property type="entry name" value="SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="41452" checksum="C25ADD671BA3B559" modified="2024-05-29" version="1">MATPFQTEAWTEYGLGVLIILLRIFARWKIVGFNWQGDDYFAILCLIFWTLELCMLELIGQNGTNIGITNDIGATLTSEEIAKFEFGSKCLLAGWNFYVTLIWCLKACILFFFSRITLATRQQKIVKWTAVATGIAYVGVISVIWGHCTPVQRNWQVVPYPGDECTLAVANYLSLVVLNISTDFLIVSIPLPLLWAVKLSIKRKLAIGLLLCSGIFVMIAALLRCILSLKDIEGINVSTIWAIRETFVGIIAVNAACIRPLFSSSRWLRSTKGSSGANQKYPSSGDRYGHQLVTIGGGGGQSADRSGLPAKKRYNKYSMTELDNNSSEEQIVKSSDSSNWPQNGGRDGSLNSTSSGQHGHGGIVVTTTYEVKPENKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHN4</accession>
    <name>A0AAD8XHN4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_609090</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368454.1">
        <property type="nucleotide sequence ID" value="XM_060507510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHN4"/>
    <dbReference type="GeneID" id="85391409"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1728399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="440" mass="47289" checksum="36D57362D934299D" modified="2024-05-29" version="1">MLDIYQINLAGLLLACGVLFASGSQDKSNTSKKDEKKSSQQKPKQTGSQWAFYVVYALVMGSDWLQGPFLYSLYKNEHQISADFVPTLFTTGFVSGAVAGYFIGSLADRHGRKASCLFFCAAYALSCILTTIPSVPLLFIGRVLGGLGTSLLFSVFESWMVTDFHARHLSEKGMDLSRTFGLMSTVNSIVAIVSGVVSEWLVSVTGTRKSPFLASVGLLVVAAGVIASQWDENYGSAGQASSSEKSNTNKPSLWATMTDKRVLTIGLASTMFEGSMYLFVVLWSPVLVSASSSPETLPYGIIFASFMASTLLASLLYPRLLALVSTPSRLLLSVLFAANAVFFALGTGAPRAEQVTFWLFCLFEACVGLYFPSMGYLKGKVVDDGVRAQVYGVLRIPLNVFVVVSLMFSSDGQAGKVFLVCGMLLQASCGALWLMGGQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHN6</accession>
    <name>A0AAD8XHN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar-sorting protein SNF8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_749928</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367687.1">
        <property type="nucleotide sequence ID" value="XM_060513844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHN6"/>
    <dbReference type="GeneID" id="85397742"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000397">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="27428" checksum="D2E54BB419C47CDD" modified="2024-05-29" version="1">MSRKGVGLAAFDRSRITSAQYASHGSNLRTTNSQALETQLSVFRSLLQQFAQTHAKDIRSNPSFRAQFARMCSAIGVDPLASSSSSSGGLLGRSVNDFYFELAVRVVEVCSATRDENGGLIGVREVRERIMKGRMEGASEVTEDDVLRAVGTLKPLGSSHSVIKVGSKSYIRSVPKELNTDQSAVLEAVQVLGYVSISMLMVNLRWPRARAQTALEDLLGEGMLWVDRQCPEWEYWSPGFMVDTGEATAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI35</accession>
    <name>A0AAD8XI35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_579127</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364210.1">
        <property type="nucleotide sequence ID" value="XM_060505204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI35"/>
    <dbReference type="GeneID" id="85389103"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF27">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="25"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="500" mass="53326" checksum="F9E05D98EA8C2C54" modified="2024-05-29" version="1">MTTDSEEEAATTAPVLLSKTRAGIVIAQICGQLFFSSFCNGIIVVALPAMQHNLDLDEGLLVWPSSSYFLTAGSCLLLAGSIADVVGNKRVNLTGSFFSAIFAMACGLAQTGGQIIAFRALQGVAYAVITPSSISIISTNMEEGRPRNMGFACMGFSQPLGFLFGLVLGGVFTDNVGWRPAFYLAAAASAALFLVAIWALPRDLQSRDDRSIWKRLSKDIDTVGVVLVSTGLATLSYVLASLSADIKNIRKPSSIALLAIAGCSIPSFIGWMHHRVKSNKTALIPNSLWGSYVFTSCCVMVLLTNALTNCMELYSSLFFQQVQGLSATVASVQVVPSLAAGALTSIATGIFVHRMPVLWMLLISSAMSTVAPLLMALIRTNQLYWENAFFAQILTPISCDILFTVGLLIVSDVFPKRMQALSGAVFNTCAQLGTALGLSVAQVIASSATNASSYADKSSPDALMAGYRVAFWAMFGWMMFVCLVCVFGMRRVGVIGVKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI82</accession>
    <name>A0AAD8XI82_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 15">Aurora kinase</fullName>
            <ecNumber evidence="1 15">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_649697</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1 15"/>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367406.1">
        <property type="nucleotide sequence ID" value="XM_060510303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI82"/>
    <dbReference type="GeneID" id="85394202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032133">
        <property type="term" value="C:chromosome passenger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045143">
        <property type="term" value="P:homologous chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044779">
        <property type="term" value="P:meiotic spindle checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032465">
        <property type="term" value="P:regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902115">
        <property type="term" value="P:regulation of organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072479">
        <property type="term" value="P:response to mitotic cell cycle spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="124"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 13">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="12">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1727351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="394" mass="44815" checksum="FBD62A642C45FF0F" modified="2024-05-29" version="1">MATRTLESRFERMSVNDENEPVDGGKLYSKTQTLVKTSQLSQSSSRPNLIKVALQSQSTNAVASVTLPSQNAQRQAKNPASPARKPLPSSSSRTSDEVVEIERKSGVSIVIEPSMPKVFHLGMFEIGRPLGKGKFGRVYLARERTSGFICALKVLHKNELQQGRVEKQVRREIEIQSNLRHPNILQLYGHFHDSKRVFLILEFAGKGELYKHLRKESRFPEWKSAQYIAQMASALRYLHRKHVIHRDIKPENILMGIHGEIKISDFGWSVHAPNNRRNTMCGTLDYLPPEMIKPGSSDNYYNEKVDLWSLGVLTYEFLVGEAPFEDTPVMTQRRIARADMTVPSFVSPEAKDLIKKLLVLDPEKRIPLEQVQTHPWIVKHCVKGERAANREKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR0</accession>
    <name>A0AAD8XIR0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAM-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_610449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368216.1">
        <property type="nucleotide sequence ID" value="XM_060507592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIR0"/>
    <dbReference type="GeneID" id="85391491"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="41903" checksum="58B9E3875386B417" modified="2024-05-29" version="1">MLNISDRSPAPIETITKPTQQQSSIAQSSIIFPSETCHQASINQLRSTRRGNKYKHVTTMSQFNHEPNSQSSSPSPLLLSLAKSYPHDPAHLHKVLLPQLTHRLRLASLWSITPGTRVLDIGCGQGDSALVLSHAIAPLSITADGDTNNVSPCPAPGSAPVGHITALDPAPGDYGSPYTLAQSQSHISSSPYGAAITFHQSDAPSYLASHPSESFDAATLCHSLWYFPSADAISSLFEALYGSNITMLCFAEYALQARNPAQKPHELAVAAQKRFYELRAGAEKGFSLDQGNVRGALAPEEIVKLAERAGWKVRERGVVDTPGLLDGQWEVGAAVDSSWAEEVVAEGLGKGAEEELLGYVREIRNAVEEVKESGGRIETMDAVWVVMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ48</accession>
    <name>A0AAD8XJ48_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane protein UsgS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_300083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365635.1">
        <property type="nucleotide sequence ID" value="XM_060502247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ48"/>
    <dbReference type="GeneID" id="85386146"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN USGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="395" mass="44971" checksum="40349FD3818F329A" modified="2024-05-29" version="1">MATSEKGQRRDKLEGQIDKQLDKLPIDKERLKREFDLSHFDLNQILRGIQLTLVGAQRALQNPALFTSDHYRQAGIAVLSGLAIRLVISIPIIGVRVFLWILSFFLSLDHVTWDDQLVGGLNFIEEYVLQVPFFLMALMRYVTPTLDNMFMDSLNWVDKTYVQKHKHEDPTKLRDMYYPNLKMYKVSDGSTHTTSTAEAISMFLYRFARKGAISLAVFALSYLPIVGRFVLPAASFYTFNNAVGLGPASVIFGTGIFLPKRYIVIFLQSYFASRSLMRELLEPYFSRVHFTKEQKRNWFRNREGLLFGFAIGFYTLIKIPLVGVLIYGIAEASTAYLITKITDPPPPPAEKAAFAASQQEWTNKHEFLNLSLGDIDAIHLKSRPANPTGDAQKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJE5</accession>
    <name>A0AAD8XJE5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_650532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366415.1">
        <property type="nucleotide sequence ID" value="XM_060510381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJE5"/>
    <dbReference type="GeneID" id="85394280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081:SF2">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42081">
        <property type="entry name" value="ZINC FINGER PROTEIN DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="413"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="685" mass="77108" checksum="0ACA2D732606471C" modified="2024-05-29" version="1">MSNGNSPPSLRAVDAFARVLYRRAKASGPDFDDVANVVRRLHTVLKHLKVESEDQDSLLNSDASSVYNRQLAPLVEDCDFALKQLETMIEKYGEGTQLEERERDMLAMVRTKLANQETAIDMFLDTVQLHNPSKAQRVVDEQGGNLDNIKDKVDAIAARLFARRDSGIGDDEEDLWQQFRAELEKEGFSKEVLRKNKEVLRAYIRELEHSTGNDATAPPSVRGLLAQERAYPHPAMAVTPASYQGRDSHGPGETYGSYDDKYAPAVRGDRRMADQRSAPNLPNEFSTLSTYEREHGAEDEHNDSLALISTRDLMAMDTINHGMENLRLTAAHNYSTSPSSTSPANRYLPPDVAAARAAADFSSSPSNLGVSPRFVPPIPHASGVPPSAYGASPRTSQSRLAPDRYGMDIPLEAKWTRIRRALISPEILERAGVRYEARPDYVAVLGVLSREEITNYARLSAEARAARSSRRHNGGPPPKVGPMQGSPRRRGDSHTSSSEEPLWDSSDNSSEASYPDEEKGNKTYYIVPPPSDKEKGTSPAATVQPKPILKNKNENHVRFDPQPHELDPHASSPRSYRDDRDRRRRPSRREHRDYESRDRDGHYRDRERERDRDRGDRERDRDRDRDSHRDRHRDRDHYPSRHHRERSDRDRRDKKKAWGETLGAVGIGGAAASLLSVLTEAASVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKX5</accession>
    <name>A0AAD8XKX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Complex III subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_605774</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the UQCR10/QCR9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369283.1">
        <property type="nucleotide sequence ID" value="XM_060507343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKX5"/>
    <dbReference type="GeneID" id="85391242"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.260:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.260">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008027">
        <property type="entry name" value="QCR9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036656">
        <property type="entry name" value="QCR9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05365">
        <property type="entry name" value="UCR_UQCRX_QCR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81514">
        <property type="entry name" value="Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="66" mass="7773" checksum="8E663277D57E5CA8" modified="2024-05-29" version="1">MAAARPFYTAIFKNNFSMLGFVFATGFAFEMGFNGAMNKYWDYLNRGRQWKDIRHKYVEAADDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN34</accession>
    <name>A0AAD8XN34_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_601357</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370557.1">
        <property type="nucleotide sequence ID" value="XM_060507094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN34"/>
    <dbReference type="GeneID" id="85390993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="369" mass="41965" checksum="62FB67D12EC45E24" modified="2024-05-29" version="1">MLYMGFDTPNRLPGFWVNFEDARNGTQLAGTHDPSASPGSLAMEFTRLSQLTGNPKYFDAVDRITRFLEGTQFKSKLPGMWPKMINFREERVDTDNSFTLGALADSLYEYLPKMFALLGGRDPSYEKMYIGAMAIAEQHILFRPMVADRDDILFAGDAFVYADRIEHVSDGQHLACFAGGMLGLGGRLFSVDNHVALGEKVARGCAWAYDAFPSGVMPENFNLIPCEARKTGDTQKDDECLWDESRWKSEGDPRLKKGFRNARDPRYILRPEAIESIFLLYRMTGRQDLQDIAWRMFESILKATETEHAHSAIADVTVPPDQTRKLDEMESFWLAETLKYFYLIFSPPDLVSLDDYVLNTEAHPFKIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN41</accession>
    <name>A0AAD8XN41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_747607</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370454.1">
        <property type="nucleotide sequence ID" value="XM_060513465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397363"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002040">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF464">
        <property type="entry name" value="ABC-TYPE TRANSPORTER CICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="888"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="923"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1000"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1025"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1112"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="185"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="605"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="888"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1199"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="827"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="596"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1469" mass="162067" checksum="BCCEA34D0A530637" modified="2024-05-29" version="1">MADKDEKTNITAPDPQAAAVEPVTPREPEDATFAIDIDKADEKDESSDFDEKNVRPELRATKSHATDTSVATTTAAQRLPESKPWYKTPNPLKWGGIPPVPDEKIISREYKAGFFSLLTFQWMAPLMSAGYKRQLEPNDIWTVNPDRATDVMTDKLKASFKKHIDKGSKYPLLWALHETYFFEFWLGGMLQLASTVFQVMSPFTLRYLIQFANDAYAASQQGLPPPAIGRGIGLVIGVTVMQILQSLGTNHFIYRGMMIGGQSRAVLISVIFEKAMSLSGRAKAGGIKDAAAAANAAPVDEKGKKKAKKDAKKGEAKGPGISGDGTGWGNGRIVNLMSVDTYRIDQASALFHLTWTAPISCVITLVVLLINLSYSALAGFALLVAGIPLLTRAIRSLFKRRKSINKVTDQRVSLTQEILQSVRFVKYFGWETAFLDRLKEIRKREIHAIQILLAIRNAINAVSLSLPIFASMLSFVTYAKTNNALNPAEVFSSLALFNGLRIPLNLLPLVLGQVVDAWSSLKRIQEFLLAEEQEEDVVFKPEGENALEMTNASFTWERTATQESEKTVGGAAKGGKKVATQAPAPAKSVSKPDEPLASSGDSTGDGASTLVEEEREPFKLQDINFEVKRDELVAVIGTVGSGKTSLLAALAGDMRKTSGEVVLGASRAFCPQYAWIQNATVRDNILFGKDMDRAWYQEVINACALRPDLAMLPNGDLTEIGERGITISGGQKQRLNIARAIYFDSDIVLMDDPLSAVDAHVGRHIFDNAILGLLKGKCRILATHQLWVLNRCDRVIWMEGGKIQAVDTFDNLMRDHRGFQQLLETTAQEEKEDETAPTNLAEAPQGDKKKNKKGAALMQQEERAVASVPWKVYGDFIRASGSILNAPFLIFLLILSQGANIMTSLWLSYWTSKRYPLSDGQYIGIYAGLGALQAILMFVFSLLLSILGTKSSKVMLRQAVTRVLRAPMSFFDTTPLGRITNRFSRDVDVMDNNLTDAMRMYFFTLAMILSVFALIIAFFHYFAIALGPLFVFFILASSYYRASAREVKRFESVLRSTVFAKFGEGLSGVASIRAYGLKTHFIADLRKSIDEMNAAYYLTFSNQRWLSTRLDLIGNLLVFTVGILVVTSRFSVPPSIGGLVLSYILGIVQMIQFTVRQLAEVENGMNAVERIQYYGTQLEEEAPLHTIEVRPEWPEKGEIVFDNVEMRYRANLPLVLSGLSMHVQGGERIGIVGRTGAGKSSIMSTLFRLVELSGGHITIDGVDISTIGLHDLRSRLAIIPQDPTLFRGTVRSNLDPFNEHTDLELWSALRQADLVPADANLEDPRSKESSSIHLDSVVEEDGLNFSLGQRQLMALARALVRGSRIIVCDEATSSVDMETDDKIQNTIATSFRGRTLLCIAHRLRTIIGYDRICVMDAGRIAELDTPLALWQREGGIFRSMCDRSGIRLEDIRGASDGTAPLEIQAGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNA5</accession>
    <name>A0AAD8XNA5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_566938</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370479.1">
        <property type="nucleotide sequence ID" value="XM_060503902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNA5"/>
    <dbReference type="GeneID" id="85387801"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05352">
        <property type="entry name" value="MDH-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF13">
        <property type="entry name" value="L-XYLULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="291" mass="31216" checksum="4CF087FF42933DDE" modified="2024-05-29" version="1">MADMKDGAFKHDATTAPQSTRVLPLFSLKGKTAIVSGAGAGIGLQIAHAYAEAGANVAIWYNSNKKALDRAAEIEKEYGVKCKAYPVNVTSHQAIQESIQQIVSEFNGRLDIFVANSGIAWEEGPLIDGPMDVADRVMAVNVNGTVYCAQVAGEHFRRQKKEGTTLDGKKLEGFTTGSFIATASMSAHVVNIPQAQAVYNASKAAVVHLCKSLAVEWVDFARVNTVSPGYIKTEITAFVDEESKKQWRNKTPMGREGEPSELKGAYLYLASDAASYTTGSDLVVDGGYCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNR7</accession>
    <name>A0AAD8XNR7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_688830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370920.1">
        <property type="nucleotide sequence ID" value="XM_060511289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNR7"/>
    <dbReference type="GeneID" id="85395188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF5">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE ABHD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="94"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="388" mass="42097" checksum="9432C1E1B7424441" modified="2024-05-29" version="1">MESLFSASIEPKTAAIVATTVVATLSFLSLARLGLYPNWGTAIPNPLKTKIPTLASDEVKKLPYHPDYFPGARDVDTPYGSIRVYEWGSTTGPKVVLIHGISTSCMTLGPIAHALAARGCRVMLFDLFGRGFSDGVGDLPHDTRLYTTQVLLALASSPLAWSGTDAVRVVGYSLGGAVAASFAASFPHVVKSLVLLAPAGLIRAENFGVLAQVTFQSGLVPERILAAVTRKRLQKPLASKRSNAVEEDEDPLEKVVDVAAAEVSGPHGGSGDDQKVERKVREYVPWMVAHHEGFVKAFMSCVRWAPLTGQHETWRVLEQRKKGTTAVFIGKTDEVIDVEHYAKDGLPLLGGDENVTWKVLPGGHDFVMTKTEYIMRELDVFWGMKVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNT9</accession>
    <name>A0AAD8XNT9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoporin Nup159/Nup146 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_688884</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370950.1">
        <property type="nucleotide sequence ID" value="XM_060511291.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85395190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000645">
        <property type="entry name" value="Putative nuclear pore complex subunit Nup159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026054">
        <property type="entry name" value="Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193:SF23">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup159/Nup146 N-terminal" evidence="6">
        <location>
            <begin position="54"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="445"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="570"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="674"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1495"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1314"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1370"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="523"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="611"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="679"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="713"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="837"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="847"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="948"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1038"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1066"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1116"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1158"/>
            <end position="1173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1553" mass="161365" checksum="A919141D64A322C7" modified="2024-05-29" version="1">MAFSFANQGNATAGGGGGLTQGPELEVIQTEALGFKSIAGDAKLRLTSAWSPPPADTASLISIASRRGLVAAAGPDGITITSTDSVRKGFEGEKEGDSDVRAFQPQGKLPMPMRVSQLAFSADENYLILSAESGGGLAVYEVESLLQGATKAAFELATNGETLRALFPNPTIEKAELCAIVTNNGNLHMANLKERSVSNALKAQVSCISWSTKGKQLVAGLADGTIFQMTPEGEAKGEIPRPPNVSDAHVSSLTWLENHLFLAIHTSTSESPPISVYHLITRKLPSDFTFQKLNDPVDPFGAEKPPHHSILRLKEFPPNLSDLLIVASTVSPDIGLLSRAKSPLTSDHPVDTTGVFTTTELADDSKRASLPMTDSFENTIPIGVALDLSAKDKVYKPLPADEEIEDSPGPVPGLWVLNNEGVLSSWWIIYEDSIRQGTTYPGMAALDTSAPPAGTSTSTPAAAPAPAPASNTSAFGAPSSTPAFGSASALGSGQKASPFGSSGSKIPTFGGSSALGSKASPWGAATTSSTAPATSGSTFGSGSPFGGSSATSGSPFAQASATKSAFGTGGSFGSPSATTPAANKSAFGSGPAFGQPSSVGFGQSSSLGQKSSPWASGGASGANTSASPAFGQPSSFGTSENKSVFGGGSAAKPAPASGGFSSFASSGGFGSLANKGNEGSSVFSSKPSSSPFGSGGQLGAASKDTAFPPPSSTGPATSNPFSQPFKLGTTFEADPSAKDDDEKPSTPGGSSLFGSNFGSALGSAVTKTPPKETTTESNEETPKPKSVFSLGQSTTPKETPAPSKFGFPPTSTSAPKSGLFGFPSQPATGGLFGSAKPVEKTPEVKAESSTPLPPDTTSKNSYPLGDSSSSSGTGNVPSDGGSKASPQVDNAPLPPDFLTTPKATSTKAANAAPLPPDFLKPSKPEGSTTPADEAPLPPDFLTPKPGKTAVSATPSAALPLPADDQSSPEELERPKSTAPAAAPDFLKMPKQSLSSATWSSTPQNTTPAVNDAPLPPDFLTKPKEPAFPSIPTVPDSEHDTDLEDEDDDDESEGSGVIVSKDQSPSMTAMTPTAGMTPQSSFGGVSSSTYSVPRTEEERPRASLFGDLSRNAPMFPRPSQTSPRSPSPVRGAVPGRIMRQESARSVSAPGMASQILAAQKQQPSQMGSSIVGNKSNDDHFIAQQRLARQRRQAEETRALEDEEDDEIQKILASKIEPTLKLDDFIAHSNVVPSAKETIPAQVEAVYRDINSMIDTLGLNARSLASFLMGHDIGFKAGGRRKQDLENPDSWVLCEIDELGEVVDRSLAQDLEDGRVHDVEEKLEACNELAREMSRLRSKQDDLKKIIMVKTDPDQADISRSLPLSTEQASQQNELRREYTNFTKLLAEAEEALTILKTRIAAANSASGKGNSNMPTVEAVMRTIGKMTSMVEKRSGDIDVLENQMRKLRFSSVNSREGSPLVTPQRNSRSILFSPERSAVMASPGTLRNSMVSSVASYGGRGGTGTPPRKKLSGFSGEEKSELMAKRAKRQAVLNKLKANVERAGVSAWAMEDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPM4</accession>
    <name>A0AAD8XPM4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucanase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_565198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371246.1">
        <property type="nucleotide sequence ID" value="XM_060503722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPM4"/>
    <dbReference type="GeneID" id="85387621"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09220">
        <property type="entry name" value="GH64-GluB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.50">
        <property type="entry name" value="Beta-1,3-glucanase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032477">
        <property type="entry name" value="Glyco_hydro_64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037398">
        <property type="entry name" value="Glyco_hydro_64_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042517">
        <property type="entry name" value="Glyco_hydro_64_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165:SF1">
        <property type="entry name" value="GLUCANASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16483">
        <property type="entry name" value="Glyco_hydro_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52006">
        <property type="entry name" value="GH64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH64" evidence="2">
        <location>
            <begin position="3"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="424" mass="44991" checksum="24ED31BF3FD6D295" modified="2024-05-29" version="1">MTRSTLDIVLKNNTGSANAYAYVTGLDLNRNNAVFLLQADGVTGYYPSSPSDILQDVGADTAIPLGAPGSTKKLTIPQIAGGRIWFSRDGPLKFFLNPGPAVVEPSATNPADPNYNLNWGFCEFTFNSFQVYVNISYVDFVSIPVSLTLENDAGTVTNVQGFPSNALDTICDKLKAQDAADGAGWSNLVVRTADGSANLRALSPNSGIVMNQNLFNGYYQPYVDAVWAKYRSADLTVNTQAEWGDVKGRVGSDNLLTFDDVGSFAQPAARDIFSCSTGPFGGYPKNQAEMGAIGARIAAAFNRSTLLINDRQPEGESVANYYKDVRTNHYSRICHEVSPDGRGYAFPYDDVSSSNGTDQSGSLFDSNPKLLTVGIGGGDGTTAAAAAAAAEAPTEAATKEAVTAPATSSEKQPQKEEAQSQKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ37</accession>
    <name>A0AAD8XQ37_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_597765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371573.1">
        <property type="nucleotide sequence ID" value="XM_060506913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ37"/>
    <dbReference type="GeneID" id="85390812"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="762" mass="83758" checksum="6762F5950E9CBA08" modified="2024-05-29" version="1">MDSTQTPPRLLLRKNGRPQACEPCRKRKVACDHAQPVCNRCRKSKRPGEVCEYILGDSPATSRETPRQTRPREQRRASKAPSIPLTSNFQPTVIPISQLSPRSTAVSRTASTATATTSPATSTIRHRPSIPASLPTSPDSAGTAATPAVTPAVLGIGYLGFTSFCGIYEETRSSLKQLQPSSAAPIGEIGTTAYCGLECSPPLTAQALETCLTILRHIPDRETGLNLFDSHLSPSDGWIRLAAKHMMISLYDTFPQYFAAGENDRRPDDAQLTSLARTICGNTAKCVSDEESDPAKWMAQFTGTNLRWESLGVMFAYWELAARYIGPYRPDVGSRFQCVDEGTKVVMQYRYCLGACIELTKAAGSGGNTLLLFMCSKRTIIESLFSGDASFACWQLHAETVALSTFLGFHDEVAAAPGVGYKPTVCSEIKRKLFSYVFYVDKVLASFAGRPPLISRRYARTPPPLDLKDDHLLSDEASLARHVAALDENGWNTEGGLYSATIVRARVMLAHIRDEIFEIALGQGSVTLVETLLEIKERQLRTVAGFPDIMTLKEEDVQNRKLDISILYTRLIMKLEHLQNMFFIERLLAKRGHDDGALLSVSYEMVSKTLMFWTNMDRLSCMNGDFEWLVMAYAAPGGGILCMELLKPTLHGGHHPQNPQVSRSSIIQKLSLLVGFLDWVSPTAPNGDLCADCKVIIQRVLDQALNSPAASASSAVDGGLPAGAMLDIPMDWDFSTQLDFNFDLLDTFDWLRPEVSSSQQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ51</accession>
    <name>A0AAD8XQ51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_598213</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371697.1">
        <property type="nucleotide sequence ID" value="XM_060506940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ51"/>
    <dbReference type="GeneID" id="85390839"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="101"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="211"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="32665" checksum="2D9B86D6857B2434" modified="2024-05-29" version="1">MSSAIGMEAVVAAAAGATLSVDFLIHPMDTLITRMQSPMYTTQYKSVNGAVSRTLFLGLYQGFGPTIITSIPSSAAFFTIYEGLKGYALRAKEEGRLAGVPLPVLYGASGAAASLVSCAITNPAEVLKQNAQVYRREPSHSGGGVGSGKVTSPTMNTLRRFAKQPTKLWAGYTALVASDLPNTTLTFCLYETLKERFLGGEGKSRERSASQQVLASGLCAAAAGSASSSLFVPIDVVKTRMRLAAGGEVTGENGPSKTSIGSPRAKIGPIAVAKGIVLKEGVRGLFRGATVTVLAAGFGGGLYIGCYEAIKIHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQG9</accession>
    <name>A0AAD8XQG9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPI-anchored wall transfer protein</fullName>
            <ecNumber evidence="9">2.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_564108</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">A acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Endoplasmic reticulum membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the PIGW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371753.1">
        <property type="nucleotide sequence ID" value="XM_060503609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQG9"/>
    <dbReference type="GeneID" id="85387508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032216">
        <property type="term" value="F:glucosaminyl-phosphatidylinositol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009447">
        <property type="entry name" value="PIGW/GWT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20661:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06423">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017321">
        <property type="entry name" value="GWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="499" mass="54351" checksum="42F6A04A4D515B0B" modified="2024-05-29" version="1">MSDATAASYKKLKEDFVSNLSGGSASEVNYVTAVAPIAILLWSVLQSRQSFFKPYTLLGAAADFLLNVTAILLSTTLYASSPLLLCALLLGPAVLIYTLPSNFGVSRKKPAIPPNAKPKAGSGAGPLSVLPVKPFLTHYRGSMLVITCIAILAVDFRLFPRRFAKVETWGTSLMDMGVGSFVFSAGVVAARPVLKERAEGRSIPLTTRLLQSMRHSLPLLVLGVIRLLSVKGLDYAEHVTEYGVHWNFFFTLGFLPPFVALFQSALKIVPSYAALAIILSVLYQVALESTDLKAYILTAPRTDLFSKNREGIFSFFGYLAIFLAGQDTGMYVLPRSLNTKSDSSPATQRKTLLMMMAIWSAVWTGLYFLTTSNSYGDGLNVSRRLANLPYVLWTAAFNSTQLLAYALVDTSFFPSFYNATDAKTEKEAYHTATSRVFRAYNRNGLFLFLIANVLTGLVNMTVPTLNVGPMATMGILVAYSGVITAIALGLDEYNISIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQH0</accession>
    <name>A0AAD8XQH0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_646038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371589.1">
        <property type="nucleotide sequence ID" value="XM_060509909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQH0"/>
    <dbReference type="GeneID" id="85393808"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="173" mass="19258" checksum="E10E25E848E1FFCA" modified="2024-05-29" version="1">MSCQLRSLEFSLADPPSRSLLYCLWSTSSDSGTIIVGLSVLSAGTKSYVELYQQVILTGEAFTRLRGIQIHDLEASFCRVTFSSVRRLHGWSAWLINLTGENFRRSREPVVCTNARATKVPRRQNKTRPPYYLPRTVWSILCITIVTTIVFGGCSAPKCALPSQPDDAAGNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQH3</accession>
    <name>A0AAD8XQH3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_725388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371865.1">
        <property type="nucleotide sequence ID" value="XM_060512734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQH3"/>
    <dbReference type="GeneID" id="85396632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="13543" checksum="8B1ACB227DDCF119" modified="2024-05-29" version="1">MAVSAMPLLPHSTSYVLATPSPSRTNRGTYRESDDIIDDSAYLTKCTKDLEVVPLALGCPYQPPPPPPPRRTDVSSSCFSLAPPSPFSNVTLPPRPRTLAAKPQPDPTTSSAVSPAGNWGKQQTTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQK3</accession>
    <name>A0AAD8XQK3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_564657</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371649.1">
        <property type="nucleotide sequence ID" value="XM_060503664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQK3"/>
    <dbReference type="GeneID" id="85387563"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000736">
        <property type="term" value="P:double-strand break repair via single-strand annealing, removal of nonhomologous ends"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006167">
        <property type="entry name" value="XPF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00596">
        <property type="entry name" value="rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="701"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="932" mass="105315" checksum="40FB41395F36191A" modified="2024-05-29" version="1">MSTNAQPVKLSLPLEYQQSLFQELRNEDELVVLACGLGLMRLVTNLLHSYDAAGNNLIILVGAEDRENNWIGEALAEHAAISQSPNARGLTVVNTDFTSVGAREKMYTRGGIFSITSRILVVDLLTNLLDTEKVTGLIVLHADRVVATSLEAFILRIYRQKNKAGFLKAFADNPDPFSTGFSPLTTMMRNLFLRKASLWPRFHVTVAESLEGKKTAEVIELNISMSEPMRDIQNAILECVEVSIHELKKGNTGLEMEDWNLDSALHKNFDVIIRRQLDPNWHRVSWKTRQIVNDLSVLRGMLSSVLSLDAVSFLQHLDTIHAAHSPPPGSTRQNQSPWLFLDAAQTIFETARRRVYSASAKAATADANIDSLRPVLEEQPKWAWLADVLTEIDNSMHFDPPARDDSNGTILIMCGDTNTCRQLRDYLQTMYFKPKVEKDPKKDDDDEDSASAAFMMRRKLRNYLRWKREFAQVNATLFSENQKALNGATDRNGQRLRGKAPSNKRRRMRGGGMAGTAQGRADNGSILQFFEKPTDVEDLMAEVQITEEEADQKPEIVTDPLENMEDFFQLYEMQDLVVIHAYDGDQDEHVLEEVKPRYIIMYEPDAAFIRRVEVYRSSHNDRNVRVYFMYYGESVEEQRYLSSVRREKDAFTKLIKERASMSLVMTVDPHGAEDPQEAFLRTINTRIAGGGRLAATAQPPRVVVDVREFRSSLPSLLHGRSMIIVPCMLTVGDYVLSPNICVERKSISDLISSFKDGRLYAQCETMFQHYKSAMLLIEFDQNKSFTLEPFADLSGSLNSIAPTNTSSDLQSKLVLLTLAFPKLRIIWSSSPYQTAEIFESLKAQEDEPDPIAAVRAGLDKDMQAEDQAFNLEPQEMLGAVPGINPKNIMRLVLATENLREVANLTERELEPMIGKESGRQVHGFFNRNVLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQP6</accession>
    <name>A0AAD8XQP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_598160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371686.1">
        <property type="nucleotide sequence ID" value="XM_060506937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQP6"/>
    <dbReference type="GeneID" id="85390836"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF272">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="39216" checksum="141F10AA14786F36" modified="2024-05-29" version="1">MIKTHFHNSFPGTIHQLIRPNISSLSPESHTITMADRYVAIHADPKGPGDARPTAEQIVRDENLVPSGLASKTALITGCSAGIGTETAKALYLAGATLYLTARNLAKARKALGDDLVNDTARVHLLELDLESFASVRACAAAFLASTDKLDILICNAGVMTPPEGRTKDGFETQFGTNHLAHFLLFNLLQPALLKAATPSHASRVVIVSSVAHRFGQPNFANINFDGCYDPMATYAQSKTANLWTANEIERRYGSQGIHALSLQPGGVITELMRHMPEEQQGGFAKHPYLSKIFKTAPQGASTSVWAATAAALEGKGGLYLEDCQIIGPWDPAGEPWGPGYGEHAYDVEKATLLWEKSLEWVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQQ3</accession>
    <name>A0AAD8XQQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_714827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371903.1">
        <property type="nucleotide sequence ID" value="XM_060511673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQQ3"/>
    <dbReference type="GeneID" id="85395571"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="335" mass="35913" checksum="6107FAA155290909" modified="2024-05-29" version="1">MRGIQIKEYVKSPKELRVTDLPDPIPKKDDEYLIQVHATAANFFDILQIQGKYQTQPPFPWTSGCEFAGIVLKAPSSNAKYPVGARVFGATQGAFASQCVAREKELLPIPDGWSYTEAAGLFITAPTSYGALVVRAGVKPGDIVLVHAAAGGVGLAAVQVAKAFGATVIATASTPRKLDVAKAFGADHVVDYREADWPAQVKALTPGGRGVDIVYDPVGMVDASTKCTAWNGRILIIGFAAGKIEKVAMNKVLLKNISLVGIFWGQYAVKEKETVVEVWKGIMKLVSEGKLRGTEFTDEEFVGLERIPDALIALGSRGTWGKVVVKIPQDGQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR71</accession>
    <name>A0AAD8XR71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Helix-loop-helix DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_746274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371926.1">
        <property type="nucleotide sequence ID" value="XM_060513242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR71"/>
    <dbReference type="GeneID" id="85397140"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF39">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="119" mass="13575" checksum="2AFA06F07998B6FB" modified="2024-05-29" version="1">MSSPNKSNSPSAAADAEQPEEKPRLTEAEKKQNHIASEQKRRQAIREGFDRLTELVPGLEGQGRSEGLVLKKTVEFMKEQLRQRQELVERIESSGGEVDEKYKRPLFHQQANSTSNRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZB8</accession>
    <name>A0AAD9CZB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial protein cyt-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_662969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369303.1">
        <property type="nucleotide sequence ID" value="XM_060511076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZB8"/>
    <dbReference type="GeneID" id="85394975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057912">
        <property type="entry name" value="OB_CYT4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056625">
        <property type="entry name" value="SH3_CYT4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056624">
        <property type="entry name" value="WH_CYT4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF65">
        <property type="entry name" value="EXORIBONUCLEASE CYT-4, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01550)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25522">
        <property type="entry name" value="OB_cyt-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23214">
        <property type="entry name" value="SH3_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23216">
        <property type="entry name" value="WHD_CYT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="557"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121400" checksum="BA472099ABB61A18" modified="2024-05-29" version="1">MLRNSGKPYVCWRCLSSRTSSSPVASGVTSALTLRQLGTGSSTESRRSYVGRRSYYSGNQGGNHRGNYDHQGGNARGGNHGNGRGGYRKPTTTATKEELKYIRQKSDIRMRLREWESANYSPSKRLLQDLPAQDTPLLNYLTRPDLLPGALGLMNGREGEVYEKTKTNRDLSKSDELQDLRGSTFALKPGDLVETRYNSGRLPILAVCIGRHNNSQYFYMSTGELVPERNIVTLFILKNFVDPYRLKPLADILPAEPETEERRNALFHNHTPAALKTAADLQRDLIKFYQDSVSFYQSQLTLDLASKHLATDERQYLSLEEIADKLLPQHVKVGDMFLPHQLYAVHTALNRDGWGFRPLNMKWHRRNYIYEVRSISDLKLLNKVENQVRELVEGAALRENPAQSLSLLRQNSLGSFILKARGVIQASRLRREWTPHGMIGPSNDEVENLATWSKQDLEYIRFMELWACHRIVPKPSQLESLGSTILKLTDCYKDSEWVAHWTAFTFLQEIGWIPPWDIPARYEYKLAGTTVQRGATMETPLVDVNESLRPDIADGHRRDWGKTTIFCVDSEQTADVDDGFSVEAAEKPGEYWIHIHIADPASRIDPKSALARQLEKAPSSLYMPGYNQKMLPRDLEQEFSLNPGRPSLTFSAKVNEVGNILDYKVEPGTVQNILHIPKNEVTGILPGLETQTVSKTFVVGKPPPPPKPVKRITTAADLSPEDRDDLLLLNRLCKALKHRRVEKGQLPPFETRFDSPKVSLDHIVVKGDADDLTRSMAWQGDPFIEFNTSTYSKADRLVETLMHTAGEVAAKWCQARAIPVPYSTQPDAVTNAKGLAAYRREHIDPLSAEGKPIPAEHIHRLLVYVGNSELSVSPAPFYAVGVDAYAKSTSPIRRFNDLVVHWQIHAALAYERETGGSLVGEELLSDDNAAAILPWTHRSLSDALPMLHALQRQIKQVDNKNAPTHWVAQALLRAWRFGEAPLPKTFKFVVDAVYAFGLRGRLSTFYNLGASVDLIRLEGYSRLADVQADDVIDVEIADINVVTMQIWCQPVGRRRVDKKKMAKKDATPARDAVAATPMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZV5</accession>
    <name>A0AAD9CZV5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DUF221 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_748293</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369602.1">
        <property type="nucleotide sequence ID" value="XM_060513591.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397489"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF20">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="779"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="825"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="871"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="926"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1000"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1038"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1072"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="80"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="286"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="666"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="780"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="10">
        <location>
            <begin position="1236"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="351"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1122"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="380"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1127"/>
            <end position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1316" mass="147188" checksum="0F43F768029EDDCB" modified="2024-05-29" version="1">MSTTPTATPSGSATLTGTLASSLASSLSTALSTTLSATLSSNGTITSTSSASATSDTAAATTSALNVAGSEKYQGITLVAFLTALLTGLVVFAIQILAFLLLRNKIARIFKPKTYLVPERERTESPPSAPWSLISTLVKYNDREIIKKCGLDAYFFLRYLRTLLTIFIPIAAIVIPILTPLNYSDGQGHDLVDEAKNDTANGTSSSPVRLMARANNDASTVPTGLDTLAWGNVGKNHTGRYWAHLILALLVIVWVCTVFFFELRVYVKVRQDYLTSAEHRLRASATTILVNSIPSKWLTEEALSGLFDVFPGQIRNIWLNRDLTPLLEKIQQREDVHLKLESAETDLVKAAKKKQLKRKKQEEKAARKASKSKGPSRQEQALRRQAEDAEAKKRAEAGQGVSSGEHDEVPHDISAVINENRDDAKSRRSSTSSSSSSEDGNRPQSKGFGLGLIGDGVTKVGKGLLGGLGKAQKEIKEFTEDVDDTVETTNGFAMLHPDNRPRKIQILADNDRPATPKSTKDTTEQVEPLANTETQKTHSRNVSAVSQETADPNYKRSYEPFGNGNTVRKVSNLDHMYDQETRKFWQFWKAPAGGYASPVPQGFDGGEYPFNQKSKDKTLWQNIKSYIPFMGDDEQIPVDYPEWNAVGGEYKNILDDDAEWRKWVKEKDRPTHRLPRWGFPNWLAWLTFGPKVDTIYWCRSELARLNVEIEDDQAHPERYPLMNSAFIQFNHQVSAHMACQSLMHHIPKHMSPRINEVSPRDVIWDNMAMKWWHESIRSGTVTIIIAAMAFFWAIPIAFTASIANIDGLVERFPWLDWIKKAPIDNVASAVAGVLPAILLALLLFIVPHILEQLALFRGVKTGSQKAEFVQRFYFVFLFIQVFLVVSIASFFTASAEKLAKNVEDLTNVTSILDLLADNLPRASNYFFSYMLLQALSVSSGTLLQIGAVLVWYILARILDSTARDKWKRNTTLSKIAWGQFFPVYTNFACIALVYCVIAPLISLFAVLTFGLLWFAQRYSMLYVTRFENDTGGVLYPRAINQTFTGLYVMEACLAGLFFIVQDEHNNNTAVPQGIIMLITIGFTAVYQISLNTSFSPLFRYLPITVEDEAVIRDEAFQRAQNKRLGLGDDDDDEDDEKTPMRNGDGAGSVNRDIEMQTMSNGAPKRKPSTMRKVKDVGHWAKREGKNLRSKTWKMGPAPVHTAAEYRRQQRNKDLEAQRALGEALYGGFHDEIEDLTPDERDALVKNAFKHYALRARAPAVWLPRDDIGVSDDEIRRTKEYSEHIWISNEGTALDSKVRVVYGANPPDFSEIDIINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1L1</accession>
    <name>A0AAD9D1L1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TCP-1/cpn60 chaperonin family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_559567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370728.1">
        <property type="nucleotide sequence ID" value="XM_060503550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1L1"/>
    <dbReference type="GeneID" id="85387449"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="402" mass="43036" checksum="F91A9DA36C62412B" modified="2024-05-29" version="1" fragment="single">MQRALSSRARASVLSAAPSKFRAGAGLGQQLRFAHKELKFGVEGRAALLAGADTLAKAVATTLGPKGRNVLIESSYGSPKITKDGVTVAKAITLKDKFENLGARLIQDVASKTNETAGDGTTTATVLARSIFSETVKNVAAGCNPMDLRRGIQAAVDEVVAFLQKNKRDISTSEEVAQVATISANGDQEVGNLIAKAMEKVGKEGVITVKEGKTLVDELEVTEGMRFDRGFVSPYFITDAKSQKVEFEKPLILLSEKKISAVQDIIPALEASTQLRRPLVIIAEDIEGEALAVCILNKLRGQLQVAAVKAPGFGDNRKSILGDLAVLTNGTVFSEELDIKLEKATPDMLGSTGSITITKEDTIFLNGEGAKDSISQRCEQIRGVMNDPTTSEYEKEKLQERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1S5</accession>
    <name>A0AAD9D1S5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin-conjugating enzyme E2 Z</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme Z</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin carrier protein Z</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin-protein ligase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_565841</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370742.1">
        <property type="nucleotide sequence ID" value="XM_060503805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1S5"/>
    <dbReference type="GeneID" id="85387704"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23809">
        <property type="entry name" value="UBCc_UBE2Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF26">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2 Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="15">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="15">
        <location>
            <begin position="293"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1730687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="446" mass="51545" checksum="A38A9A5813DB1FAA" modified="2024-05-29" version="1">MADQSIIRITKELGDIQRTSDLSIAVACRDVDVRNVKALIIGPHDTPYEFGFFEFAIRFNKDYPRKSPNVNGITTNGGRCRFNPNIYSSGKVCLSILGTWRGERGEEWSAAQGLESILISIQSLMSGNPYENEPGFEEANEASDKKNQKDYVQKIRHETLRVSVIQRMEEYLGLTPDGNAIAQQSAADGDQLDIDNDDIDDTNVPFEPFKDLCKRRFLWYYDNYLLAVQKAKAEVKDHQAFVRMPFEGASNTMDGKFNYTELERRLRNVKAALDNELVKWAKDGEVAIEKEMTLSVNLRHQYEQVVQAFKRQDIPHDVQLEDNNPFVWVVTYFGRPMTNLDGGLFRFKIHFSTKFPEEQPRVKFHTRIFHHRIAEDGTVCYFPNSLRKEDVRTHIEAVFTALEEEDPAYDPRTLVHPEAHTLYWGGAEARKNYNRRLRRSVQQSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2M6</accession>
    <name>A0AAD9D2M6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_290323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370999.1">
        <property type="nucleotide sequence ID" value="XM_060502182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2M6"/>
    <dbReference type="GeneID" id="85386081"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF14">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="367" mass="41805" checksum="15D5AA8AB615F79B" modified="2024-05-29" version="1">MSQTTVMSFLPPGVADGRLHGFEFTFEAIPDKSSLHDSHIEVDPDPHEGETESLPDDVECFPRHFGRTYHAYRAGSYVFPNDPAEQERLDLQSLALTELFSGRLHFAPIAVEGSPKRILDVGTGTGAWAMDMGDVYPEAKIVGIDLSPIQSNAVPPNVHFYIEDAAQSWQWEEPFDYVHTRVLLGSFGDFKNEVIRQAFDSLRPGGWLESQDFNLEATSDDHTLAPDSPLSRWVDDMNLASEMIARPLSRAHMLREWYEEVGFVDVHQRVFKIPINGWAKHPRHKHVGRLWEQNFLDGLSGFSMALFTQVLERQQEEVQVSLVDVRRDISNMQIHAYQHVWVVWGRKPYPDEAIPAQSPPENKEMTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2S5</accession>
    <name>A0AAD9D2S5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_565429</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371149.1">
        <property type="nucleotide sequence ID" value="XM_060503753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2S5"/>
    <dbReference type="GeneID" id="85387652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="633"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="816"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="882" mass="95985" checksum="9B8B35B2C77D739E" modified="2024-05-29" version="1">MNGLPPPGIHPVAMSRPQVGIERLPTRRLSNEPRESMNCKSCRKRKIKCNRLRPSCEACQVFQCPCVYDAVPKKRGPKTDVLEALLKRVDGLEAKLKEKNAGEQTPTTPTTAGIKDEETSRADDIPDDDPNPKRIALDTKVDADESAVYSPAPASEPSPPTVQPDALLDTYFSRFHSKPYHILDESSVRQRLQLNQLPNYLVHGIYAVAARYTPHPSGYQSAVHLSEDFASRARAEIDTDEPSVDALQALLLLVIAFTAAGKGKKAYMLMIGMAMALETHREMDNNARVTPVEREMRRRLFWTCYLLDRFLACGSKRPSLIGDKTILLRLPCWSPNPSVPPIDGEFFQSGSNLQFLQGSGKKSQGSTGMLIDISRILGITNRYLAAGGVKGDSHFPWHSLSNLSKIRQDLDIWASGTEDVFSSLDTLFGQPDSTILVLSKLIYHLIHCLIYRPFLPIDLAELAGTGQHQSWQIEATNMCFLHANAISELVELGKQTGTIEWPAFVGYCICTAGTVHIHGAHYNKNGNGDSTVFSMSADFLSREMQQLSELRYAWASVQHQRETLQGIYNAHSELVKSLANNPMRYSPAFHLEDFFDRYSNIGGPGGQTFNFDAANLSLSDVIVDFTTDTYTGHDLYAPRANSMNEPERPSLKRKNTAPSSRKRPDAKVLSPLSTSHMARPHGLPTPSHARHSFSHPTPTMASHPSPGMLATPTSLPPHPETMEHPSMSASHGQYDEAAANNAAVAAAAAAGFSLGPQSHQQANMPALSSNSFSPQFSFATPGANGNNEVGGNYNDPMFGGLPTNAFGSPAAWHGDDGGNKVAGVAAPSPGNKSNNGSTGTGPGEEKDPFLSLLEQLAENEHQFARGPGSELDFFFGGTGASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5H7</accession>
    <name>A0AAD8U5H7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_644037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000238">
        <property type="protein sequence ID" value="KAK1705648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357672.1">
        <property type="nucleotide sequence ID" value="XM_060509717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5H7"/>
    <dbReference type="GeneID" id="85393616"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF4">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1705648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="50666" checksum="F047056D8B732870" modified="2024-05-29" version="1">MSDNTAESILVPFLGAFQASLSVLLTISAGVIAAQYGLLDDRSSKKISTFCVRMALPALLITNVGSQLDLETGIRYVPIIIWAIFYTTVSIGIGFVLTKVFGMPDWVIPAIAFNNTTSLPLLLVQSLDATGILSSIDDSSGVVTKAKSYFLVNAMIGNSLTFALGPKLLNGQEEEAPDKVEGDQNNDDDNESDGEEDLESQEQDAIEHNEQTSLLPDRTVTRITRTKYRVYGKGSKYWSNLSPTSRSILEFLYSFVNAPVIGALIGALLGLVPALHRLFFNEPEEGGYFNAWLTSSVKNVGELFAVLQVIVVGVKLSKAILQYKNGEDSKESKVPVVPFLAVTFVRFILWPVISIGVIYLLASRTELLTKDALLWFCLMLMPTGPPAMKLSALADVDGSEDALKMLIAKFLTVSQRPLNSNPPMRGIFADNIPDVLYHITSDLLYGGWCSESKRGHCCQVDTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5I4</accession>
    <name>A0AAD8U5I4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease H-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_643973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000236">
        <property type="protein sequence ID" value="KAK1705783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357687.1">
        <property type="nucleotide sequence ID" value="XM_060509711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5I4"/>
    <dbReference type="GeneID" id="85393610"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43040:SF1">
        <property type="entry name" value="RIBONUCLEASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="40"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1705783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="34572" checksum="DC27F801F688E715" modified="2024-05-29" version="1">MERQHRHTMTESPPSESNPVGSFPGSASAYVSNSTTQLAYDLINTSEGISTLVDYLSGLPNDATPSHYVDLEGDNLSRHGIISILQLYVAPKQHTYLLDIHALGQRAFSTQGERTGKTIKDFLENPDIKKVFFDVRNDSDALFHHFRISLDGIQDLQLMEFASRYNKAGFLSGLAKCIERNAPLTPEEIFSWRAVKVIGHNLFNPQSGGSYTVFNQRPLSPEILRYCIQDVQYLPRLWHVYDQRLGESWKHAVVEETKNRVLQSQGSDYNGQGRHMTEPPADWVVRKPEIASTIHPEPSTITRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7Z2</accession>
    <name>A0AAD8U7Z2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_769510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000211">
        <property type="protein sequence ID" value="KAK1707349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358037.1">
        <property type="nucleotide sequence ID" value="XM_060515326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7Z2"/>
    <dbReference type="GeneID" id="85399224"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041772094" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="44"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1707349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="61636" checksum="BA8F8A9EBEEA595A" modified="2024-05-29" version="1">MFASHTEGGSRLRAGAIGALLFVAASGSPVVGNSSRVVHVPSYGSYVGKTLFNTTSGYPLASPVDAWYGIDYAEQPIGDLRFAPVGWPSSSNGTKNATSYGKVCIQEPGNSNLITYITTGLKYGEDCLNLNVYKPTGVGADEKLPVLVWIHGGLFRNGAGITFDGASLVASSPEPLIVVTFNYRLAALGFLANPVLSDLGNVNLGLQDQHQLLRFVHRYISAFGGDPKRVTLGGKSAGAHSVGFHYQNTFTPGEELFQQAIFQSGGPTGRSFPSASDPLTVRQFEQYVSGVGCQSNETAEILLSCLRDVDVEVLEETATALLAAYRYNGTHPFQPVSDAIIIPRLPSETWDSDTWNHLPALTSFIVDEGSLYAPTNLTTDDEAWSWLSNLYPGLNESDREGFSRLYPDPETDPASPFADSQGQSAQFTRLTAVYGDTSYISASQEIATRLSAADVPVWKLHWNTNNSVASYLGISHGSDVPYAWAEPDTQYPQAGTTLSRFYASFVVSGDPNEFKAAGAAEWKKYNDPGSDGLGWQVNVSKNETWLEKDDIRREAIEYWRSIPEKLDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8I0</accession>
    <name>A0AAD8U8I0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="6">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIF6</name>
        <name evidence="7" type="ORF">BDZ83DRAFT_710182</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <text evidence="6">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8I0"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1712574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="26580" checksum="79B7C3B16AB530E7" modified="2024-05-29" version="1">MAVRAQFENSNEIGCFATLTNSYALVAPGASENFYSVFEAELQGVIPICRASIAGVRIIGRLTAGNRKGLLVPNTTSDQELQHLRNSLPDEVRIQRIEERLSALGNVIVANDHIALIHPDLERETEEIIADVLGVEVFRQTIADNVLVGSYMSLTNQGGLVHPKTSIQDQDELSSLLQVPLVAGSVNRGSNVVGSGMVVNDWMAVTGLDTTATELSVIESVFRLGEGLGPDNVNTKLKDTMVESFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8W8</accession>
    <name>A0AAD8U8W8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_644660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000268">
        <property type="protein sequence ID" value="KAK1704183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357390.1">
        <property type="nucleotide sequence ID" value="XM_060509768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8W8"/>
    <dbReference type="GeneID" id="85393667"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="15"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="44"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1704183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="368" mass="40778" checksum="D2D4AE021DCD71B5" modified="2024-05-29" version="1">MAPNLPIGGSGLRASCEACRVKKIKCTGERPICSKCRSSDRECYYSPHKPMGRPTSRRARPQSSQPIRRERILPRRNASTRLLSPVHTDAASDSGNSNTREIDALLRSTSPQISSPLNPETHAIHPDLIDLEDNQGPSQDLASEGLAAFPPLTSDNQQTTDNCACLSVLYLLLEHLRVKEHLVAPDDFALLRNTFEPALQVLNCQRCPRRYFSIIQNAALLGVLCLCLTESYKRMLASISTEETRATEAGEKKRLGIHGALPGSSAYGAPSSTSAPSLFSVEVSPSEWGKIMRNIVRSEIFGAEGQKDNKYLTGFFDLMEQRQRRWHHTPPAPDCPPCYQSFCGSDDRQPSCLALLNNARQLIEHLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8X7</accession>
    <name>A0AAD8U8X7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358547.1">
        <property type="nucleotide sequence ID" value="XM_060509558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8X7"/>
    <dbReference type="GeneID" id="85393457"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="121" mass="14154" checksum="A6ECDBAF7AB9FFF7" modified="2024-05-29" version="1">MADEEGDLFNIAIDDSDEEEQKPRDWQSEEDFQNLRATYRVKVQDGDVWQTIELPLNTEKASKPVLQELLHAVEELYFLRRFGEAAAFARRVLDGSEAALDRDTKETLVRYEEKCRGRMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9K2</accession>
    <name>A0AAD8U9K2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_641270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358588.1">
        <property type="nucleotide sequence ID" value="XM_060509546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9K2"/>
    <dbReference type="GeneID" id="85393445"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1709454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="59908" checksum="A0CD02379036D66C" modified="2024-05-29" version="1">MAAQAHRRSRNGCGTCRTARIKCDEARPFCKQCERRGVECVGYQIHLKWVEISDISPDSQSASKSVIKPRSSLTICPSKKSAACRKKAIPPTSVTRSLSVGPKLHSSSDAFIFRHWADSLPDLVYPNPEEYATIRQPYLAFVWKENSILLPAVLAAGSAHLHALGKLKHAETLERKQRALSTMVACVKQPRAISNPQFQTSFPVYLSEEAIAASAALVGMEIMQGSHTPSIIPLLRGLKAQMQERQNLRQRVAANWPMEMDTPMMAVNIKMMAYIDTFCCVPCATHPVFDEHAWHDLILPKCQDFSLANGPDIVFGYSMHILPVIGAAASLVDDFFQTTIMPEDFVSSRCQLLDELESACRDLPPPQHQPDPNTDPSAPPTSLKIRDANACIAAAQAHSLATQIFLLRADEGDSSTLAAERPTKHPLALVEQLSDAVAAVPLDTHAATMMIWPVFVLGCESMAVSARRYEVEELFERIIDKQKLLNISVALKMLRENVWTGDVTNTASRASSLSPAEESCRYTQNQWVKMCWKERLQLCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9P6</accession>
    <name>A0AAD8U9P6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_724732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000226">
        <property type="protein sequence ID" value="KAK1706425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357825.1">
        <property type="nucleotide sequence ID" value="XM_060512693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9P6"/>
    <dbReference type="GeneID" id="85396591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="345"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="673"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="675"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1706425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="748" mass="83953" checksum="0168F2A5299D9D48" modified="2024-05-29" version="1">MNVTPRGEDGRGETHDEDSPHEDIGEVSVPRISVRCDRRLPCSHCTRSGAVCNYPTKQRPKEKRQRVFISELYERKIDLIAEKLEELSQALGDQGSNKPKTNTLHSFTHNDVSLPMPPQMTQDTLTAAFTPNQGKNKIVTPKAEYEGESSLSAQAAFANRFLHDAVNNRQSTNVMGEMVSVLESLSRTLGNQKNLQDPDYLYPNAIALTPGTCVRDLPMPPVESVFVCFRMAQEHPQVKFMWNLNTALSQSFTNFFLKVYSPGDVTQADLIIVNSGLYWLFLECMYVTKEHDKRNHFEAQAIISRNNLETVLSQLPFHLPSTIEITLAMSLAALYCLEVCQPSAAWNFITTAAHMSQTLGFHSHVAMTQDNPEVQKEKRRIFWLVYVLEKGLSLRMGRSSTIRDGDITIPRPRSDTVSNADMMSIFPGSTEFATIQGMVYDQIYSPAALMQPQSVRVERARRLGADLEMHMRSVMDHVSDTRCQIPQAKIIGEQLQEAFIRTDTVNQLSLCCLIHRAIPPEAGEISAFGGACIASARQALEEHQRCMILVAGMEEYYLEAYINWALLSSPFIPFIVLFCHVIETCNESDLRLLAALVDTLRSTVADSFTIGVKKEVRMFTTLYDVACSYVKLRSDEDSSQLAEVQFKNGWEFADENVNPPVLQPSICLASPGAASDQQTLGQTSNTSNMRPFGDVLNDHEPANQEWTSGSLSRPENYLGEVDDYGSQLGNWLYMNNQMIRALENNYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Y0</accession>
    <name>A0AAD8U9Y0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_644168</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000242">
        <property type="protein sequence ID" value="KAK1705463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357619.1">
        <property type="nucleotide sequence ID" value="XM_060509733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Y0"/>
    <dbReference type="GeneID" id="85393632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF120">
        <property type="entry name" value="HIGH-AFFINITY COPPER TRANSPORTER CTRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1705463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17209" checksum="B6143FFE6AE75FE0" modified="2024-05-29" version="1">MDMPSTTSHSHGTEPMPVVFHTKMATALFSESWTPRTPGQYAGTCLALIVFTIILRTLIAFKPVLEATVWAGEHGKSHLRIDEDFAPKEKSSAPTPCSIFHRVAQCAYEVVIALLGYLLMLAVMSMNLGYFLSILLGVFVGTLCLGGIARSTTFDHCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB98</accession>
    <name>A0AAD8UB98_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_208550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000242">
        <property type="protein sequence ID" value="KAK1705464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357620.1">
        <property type="nucleotide sequence ID" value="XM_060501699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB98"/>
    <dbReference type="GeneID" id="85385598"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="191"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="704" mass="77904" checksum="630A1ABC3D67DD2B" modified="2024-05-29" version="1">MLCKSCNDLADARIEEAERHTEQARGPSSSRVLIHHATWASFEDAVGAGCHLCTSIHEELAAEGLVPDSHSDTAQLYVQAHAPTAMPSGYLVFSPSIACRTGASFYMLKNQGQSPSSDEHAESLRLVEGDIGQEDKALTSTRTWLRDCISNHAGYCGKDTGGFVPTRLLDLEVRDTDDVRLSTAVPVHETYATLSHCWGKSEILTLRRANMESFQAGIRVETLSKTFRDTISLLRRLGLRYLWIDSLCIIQDSVDDWRKESVTMAEVYRNGTINIAATAASGGDEGLYFAPHPIHSRHLRVSFNQSIDGTLSEGPTSGERPLVVEAGDYFLLNSKIWQRGVEEAPLNTRGWVLQERLFSPRVIHFSRHQLFWQCGMDYRIGQFAYSNDRIGSFGKAYTNRDPRAFSQVLWRLKSMTKEEKDPLLLEEAYLPWEEVVTTYTAQHLTKGEDRLIAVQALAKTMEEAVDDCYVAGLWESRLVEDLLWACSAQGERARYSRQTTWRAPTWSWASMNGGSVKKATLTGRYAGRKVFEGEALVKSIKHCVEGYDGVTTGQLKSARLQLDGCLLKSAISWEGHAVLSDGNVKGISMRCPDPGFRTFIVCPDEWNWDGADKLNYQLPAGSILLAIGTHLAYKAAGTDPNPCIEGLVLHDAGQKGSLSFCRTGYFKLVAEGTISNACLAGEEGALFTRHQSVSGDGTCTLNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBN7</accession>
    <name>A0AAD8UBN7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_78015</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359818.1">
        <property type="nucleotide sequence ID" value="XM_060515528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBN7"/>
    <dbReference type="GeneID" id="85399426"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39469:SF1">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042265340" description="TM7S3/TM198-like domain-containing protein" evidence="8">
        <location>
            <begin position="23"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="9">
        <location>
            <begin position="121"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="528"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="658"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="779"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1072"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="330"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="661"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="681"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="779"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="806"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1074"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1126" mass="121365" checksum="9D2CF8F2CCAC9861" modified="2024-05-29" version="1">MARWNRLITWGLLLIFLQVAVAQALVPVRRQETGTTTAAVASSTLSRSARDAETTASPASSIRTTAVATTESPSVSATVSSPPIIPTGGSTSGNSSLENSTTSEGELPIEPKVTPGWAVAGVILLCTGVIYSFIGIKNTVLHTAFSVAYVVGLGITVLVVYVMVIPVSNGSQGAYVVAAVLPAVAVGVLASWFFKEITECLACALGGFCFSMWLLCLHEGGLLTGVGKVIFIIAFSLVGFALYFSRWTRDWALMCTIAFSGATATVLGIDCFSRAGLKEFWAYIWDLNDNLFPQDTTTYPLTKGIRVEIAAIIVITIIGVISQKRLWNVIKDKRTKREEELAEAQRARDDEEANIGRELEARTALERRAWERAHGDYTPDSDDHDSGFARDSESEKAIRYSQSTATPRSRAPPVAEMQGSDVPPTVPPKPESPGLMVSEKEKEVVVTVRVAPDETHTEAVAAIKAADQTEEVSKDNAVVQSVQEVAPVPEVVPLPFSFPDEEALARDREERSTIATFADDDEDIQAGVGSKRSSFAKRLSQSSVQLMRKVSQRTSMSHRKEEDGDEVLAVLQRPRDDDAVSLAATVDTQSDSGAGTVNDEHRRSIEINAQLSGEQRSSIKPETTTSASASRRSVTDRKSVRPVSAMTAVTDIPVQSLAKDATTPAAVEESAPESAVGDVAQENSSVKQSESGESRQPPVPSQQAKSTASLHSTPLNLTQERLPPSFSNVALHYRTNEWAKHLSQADAPEPEILKIGDDRPQTREAPAPVHVEELKQTALSATPAPAPAPLRSSPPVATPPPALTRPMSTQSPNRGHSRNSSYQSHRRASSKTQFEPIAEEEQQALSRAASTRSGASGIALSATAPAVFVPPPPPPGIMSYDSPQSLIAQRSVALRNKTYGILTGANNMPEISAASYRTPSETGSMYNHPVYPSQMPPASLDDLPLSQRKEIIRRQSSFGTMRSSLEGSRSASGSYVPSVSAENLAFDSHQPMRYSNVPSQDARDARLASFRDSVRADLRAGTASPAPAANGRDVALSMFRSPSASNLAASQAAAREAEVQRNIDLQRSFMMSQKEAEAKRKEKARIDKERSDQAFTRSMQSGEMFELHREAMRRMQDQARNASGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBS2</accession>
    <name>A0AAD8UBS2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydantoinase/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_757491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358875.1">
        <property type="nucleotide sequence ID" value="XM_060514905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBS2"/>
    <dbReference type="GeneID" id="85398803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1610.10:FF:000001">
        <property type="entry name" value="Hydantoinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="209"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="594"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="4">
        <location>
            <begin position="763"/>
            <end position="969"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1710596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="999" mass="105444" checksum="79337AA5324BF185" modified="2024-05-29" version="1">MSASDGTLVVGVDVGGTNTDSVLLDVSKSSTDAVVASHKAPTTSNVTHSVQATLKALLDKSTADPANITALAIGTTHFLNAIIERDTSRVEKIAVLRLASHNFSTGTPPFADWPSALKRIINGHSAIVPGGCNIDGTLIGSIDEDSIREQARRIKSKGLKNVAVIGIGCSTDKDYHQEDEVRKILLTELGENVNIILSRNIAGPGLLARENATILNASILNFAQRTIRAFIGAMRRIGLQCPLYLTSNAGHLLPFSEAMQAPIRIFSSGATNSIRGAAFLAKDSIDKSGSIVVDIGGTTSDVGYLLSNGYPRLSKSYTALAGVKVNLEMPSVESIGLGGGSIIHSADDGPVAVGPDSVGHDLITKALCFGGDVTTATDVAVASGAKIGTTAVSLASDVVEKGKARIRKMLEAVIDRAKLSPEPCTVILVGGGSILCPSELTGVSKVVVPVHAGVANAIGASIAKIYGSAETIIHGSDIQSGIAEVKARAIQNAVAKGGDESSVTVLHEEIAGVPYVENQTSIKIEVALPADHKRVYSEMVKTAAPDQLVNEEMFEETKKHEAEDAEDHPEDEVVDLKSYKPKVESNGLWTLSETDLRFLSIGCYILGCGGGGSPYAPYLQLKQLLAEGESMKIIRIEDLKDDEMMPPVASVGTPAVSIERPGGDGVWHAMQEMEKEMKTKFEKLIATEIGGANGVATLIWGSSRYYDIPTVDGDMMGRAYPQFEMVSQYIHAKSVNELLPVTLCSGTGHNVVIPATQTDETSAGIAIRDACVAMGSAAGAAGRPIPGKLMREVGIPNTYSLAWRLGRVVALAQQAGTVSTVTKDIIEAAGGPGSARVLFQGKIRSVESTLTATAHSLGKVTVERLSESEMETETDRIGEGLKEVVVPFMNENLGVLGKGESGIETVLATVPDLIFLLDTSTGEAIGVQEYRYGLKVAVMIMAGHPLWATERALEIAGPKVFGLEHDYVPTLQYVKPASVIEEFRHGCGGENCTSCQYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC81</accession>
    <name>A0AAD8UC81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_585610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361336.1">
        <property type="nucleotide sequence ID" value="XM_060505862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC81"/>
    <dbReference type="GeneID" id="85389761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018836">
        <property type="term" value="F:alkylmercury lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004927">
        <property type="entry name" value="MerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053717">
        <property type="entry name" value="MerB_lyase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03243">
        <property type="entry name" value="MerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160387">
        <property type="entry name" value="NosL/MerB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="225" mass="25428" checksum="D596117FA0444A92" modified="2024-05-29" version="1">MDHSSLHEFIILSFLRRSRPPTIGEIQIQFQVNGKSARQGLRALADYHGVVLHPKSDEIWICHPFSASPTTCVVSSDNRQWRGNCAWCSLGVMHLADGTTTLTTRNGGIGEAISITAKNGHLQAADFVVRFPVPMRKAWDIVIYTCSVQLHFRDETQVDEWCATRGIPKGDVRPLKQIWEFAKEWYGQHADANWTKWSLCDATKIFHRHGLDGPVWDVGETSGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD75</accession>
    <name>A0AAD8UD75_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b5-like heme/steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_630572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362022.1">
        <property type="nucleotide sequence ID" value="XM_060508844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD75"/>
    <dbReference type="GeneID" id="85392743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF72">
        <property type="entry name" value="NEUDESIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="8">
        <location>
            <begin position="63"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="19233" checksum="A091C210CF516E97" modified="2024-05-29" version="1">MDYVDKRLQEEAVKLHVDQGNAFFTPLNILFLLVNIYTIYVLLRPTPPPVLPKEPPATVFRVFNPRTLLPYTGENDTPIYLAVRGRVFDVTHGRNFYGPGGPYSNFAGRDASRGLALGSFDEDMLTEDLDGPLDLLEGLGPDEIEALQGWEENFDSKYLVVGRLTAVGDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDU4</accession>
    <name>A0AAD8UDU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_74158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359939.1">
        <property type="nucleotide sequence ID" value="XM_060513091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDU4"/>
    <dbReference type="GeneID" id="85396989"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="207" mass="23315" checksum="B97FA4AE230A7226" modified="2024-05-29" version="1">MVDGVQTLDSRERHCRVAKKKSNLQILGLCQSLGKFKGDHWSSVSLAQKVGRKSVLAPRELIALGEVVCRRCRLTSNLLRIDRVCDAASVTISVRWVGFLVGHVNFQVLKLKSRQGRLLTADVKVAAAKKRFSAQETKLQTHLTKKAESLRRCVFHILNTDIRLLDLVCVWTVFPVVSVRWGHGDFSAWVEEGKMVRCRCHDAGAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEK7</accession>
    <name>A0AAD8UEK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_636142</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360138.1">
        <property type="nucleotide sequence ID" value="XM_060509231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEK7"/>
    <dbReference type="GeneID" id="85393130"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="386"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1714995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117487" checksum="A37EC2B46A8F9FEB" modified="2024-05-29" version="1">MDKGNLVQLLQASQIPDTEKVKAVTAELQKNYYSKPESLLLLIEITVSHDDAAIRQLASVQALRLTPRHWTKIDASQREAAKKHILDSILSDQSAPSRHSKSRLLAGAIGLDLEDGDGQDFVRGLLSLNVADNVAHREVGSYILFALLDNDPTHFTEQAQQLLGLVQKTIVDPASADVRLNSVRSIGALLMIIDPEEDTQSVQLVQQLVQPMVEILKNAISEGNDDYYRDVFEVFQSFLAFDSAFLGPHLKDLIHFMLELAINNEVEEEARSQSLAFLSQCARYRRMKIQGMKDMGALLMVKSMQIVTEIETDDDDDENSPARTALALIDQLANDLPPRQVIVPLLEQFPQFAQNPNPGHRKSAMLSLGTASEGAPDFVATQIQPLLPIVLTLLNDQDVSVRHAALVGLIHLADEMADELAPKHRELIGALLTNLEAVVGSTDSQSVRVIRAVCGALDSLIGEGLEDDLIKEFGPKLIVPMGKLLHHEDFSVKGGAAGAIGAIAAALGREEFKPYFAEVMGALGQYVAIKDGEEALNLRSAVCDSMGRIADAVGAQEFQPYVMDLMKASEEALSLDNARLKETSFILWASLSKVYGNDFSHFLPGVFKGLFDCLELEEESLSIPGLTEEDIPEGLLISNGKKLNLKAAADDDEEDMDEDADWEDLEDFAGVTAVALEQEIALEVLGDVITHSCDGAAIEKYLADAMGKVSPLAQHPYEGARKAAISTLWRAYARVWQLYEESTGAKWEAGYPPKQNPGQVINDLGQSVVEATLSVWEEDSERSVITEINRNIAATLKSCGPAILTHNELLKSSLTILGCLITRSHPCQMDLGEEEEEEAAEGSSEFDWLVIDTALDVILGLATVLGSDFAEMWRVYQQPILKFASSQESLERSTAVGVIAEAVKYMGQAVTEFTDSLLPVLTHRLTDPDSLAKSNAAYAMGQLIFNSQATDKTISQYPTVLEKLEPLLQIKESRMVDNVSGCISRMIIRNPNPEFVARVLPALVDALPLQEDYEENAPIYQALYNLYDAQNPTVASLTPKILPVLQAVLSPPEEQLEPETRQLCQKLAQALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEY7</accession>
    <name>A0AAD8UEY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_581969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363027.1">
        <property type="nucleotide sequence ID" value="XM_060505508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEY7"/>
    <dbReference type="GeneID" id="85389407"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="38238" checksum="76F20C3351338A89" modified="2024-05-29" version="1">MAPPASLPARRLGTTGPEITALGVGLMGLSVAYGKPGPDEERLAFLDRAWELGATNWDTADAYGDNEDLIGKWFALHPERRADIFLATKFGLRGEIRNDGTFNIRIDSSPKFCREACERSLKRLGIESIDLYYIHRLDETTPIEKTIEEMVKLKNEGKVKAFGISECSSTTLRRAYAIHPISAVQVEYNPWSLEIEGPAGTNLLKTCRELGVTTFAYSPLGRGIMTGRYKSVDDFEEGDFRRQRPRFMGDNFKKNTQLVEEFAAVGRAKHDCSAGQLTLAWLLVQGEDVVPIPGTKKIQYLEENLGSLKVVLGKEEESELRALVAAADVQGDRGAAFGNYSDSPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC4</accession>
    <name>A0AAD8UFC4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_721758</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362008.1">
        <property type="nucleotide sequence ID" value="XM_060512409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC4"/>
    <dbReference type="GeneID" id="85396307"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF9">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160948" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="19"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="17">
        <location>
            <begin position="283"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1721212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="320" mass="32152" checksum="D77BF61C8DE5331A" modified="2024-05-29" version="1">MKSAILSLLAIAANQVSAHATFQALWVDGVDFGGQCARLPLSNSPVQDVTSNDVRCNANGGPVARKCVVKAGSSVVVEMHQQPNDRTCTQEAIGGAHYGPVLAYMTKVSDATTADGSTGWFKIYQDGWSAAAGSANGDGDNWGSKDMNTCCGKVQVKIPSDIPAGDYLLRAESIALHAAGSSGGAQLYMTCFQLTVTGGGSASPGTVSFPGAYKASDAGILVDIHRALTTYVVPGLTVYAGGSTKSAGAACVGCESTCTAGSGPTGTASSVPLPTASGGLPGCTVAKYAQCGGEGYTGCTTCVSGSTCQAVSAPYYYQCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFX5</accession>
    <name>A0AAD8UFX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Salicylate hydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_30806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360843.1">
        <property type="nucleotide sequence ID" value="XM_060502294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFX5"/>
    <dbReference type="GeneID" id="85386193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1717356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10610" checksum="716634CFE01E8842" modified="2024-05-29" version="1">MAIEDAAALGVLLSNVTSKDDISTRLDMFNQLRLKRVAATQTVSSMHQWDPTRVSEEQRQYFDGDVPQTIDDIEIFSYENSVIRDAFDLLERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG00</accession>
    <name>A0AAD8UG00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_634502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360649.1">
        <property type="nucleotide sequence ID" value="XM_060509106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG00"/>
    <dbReference type="GeneID" id="85393005"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163209" evidence="2">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="77" mass="7902" checksum="6207E135D57CF74A" modified="2024-05-29" version="1">MAPHAIILLGLLALSNAAPQFTIGDGSTILVPGGGVISPNPVGPILLPPINSPEVKPGKRDLNNPIHERELSSSGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGH2</accession>
    <name>A0AAD8UGH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gylcosyl hydrolase 115 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_673216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363897.1">
        <property type="nucleotide sequence ID" value="XM_060511134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGH2"/>
    <dbReference type="GeneID" id="85395033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.520">
        <property type="entry name" value="Glycosyl hydrolase family 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031924">
        <property type="entry name" value="GH115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042301">
        <property type="entry name" value="GH115_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842:SF2">
        <property type="entry name" value="GYLCOSYL HYDROLASE 115 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15979">
        <property type="entry name" value="Glyco_hydro_115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gylcosyl hydrolase 115 C-terminal" evidence="2">
        <location>
            <begin position="795"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="960" mass="108514" checksum="E0BCDFCBDE22D89A" modified="2024-05-29" version="1">MFEKAIVTFPSPKDAEAFDLVGSTILVDESDPIGIHIAAQNLAQDFDRVTQSEQSTVQVVQGTQVDVALGSAAAIIIGSIESSSILQRLERDEKLNFDEIRGKWESFSTHVIDQPLQGVQKALIIAGSDKRGAIFGAYTLSEQIGVSPWYYWADVPPKHHTAIYALPEPTYHGEPSIRFRGIFINDEAPALTGWVRANFGSYNSEFYKKVFELLLRLKANFLWPAMWPGYPNPGASFFTDNPLNPKLAEDYGIAVSTSHHEPMQRMSNEWFADNPDGSWNWLTNKEKITAFFDEGVKRAKGRESYFTLGMRGEYDRKMKTDDPAAVVRDVIKTQRALIKQVHGREDAVPQLLALYKEVQEQYEEGNLDVPDDVTLLFADDNFGSIRRLPSGAERDRKGGAGIYYHFEYVGVPRSYKWINSNSLGKTWHQLQEAHKRNAKQIWVFNVGDIKPMEVPLTFAMTLAWDINSIGANDFENFYQKMAESNFGNDQSEEIASVWHKYDRLSALRRHEHIEPTTFSLIHYNEAEDVIHRWGSLLRSAEEIFNQTPKDQKAAIFETVLHPVKASTIFTKLQVTLGRNRLYARQRRNVANKLAREVLDLFDADYALSEEFHALLDGKWDQIMSQTHYGYEETWHAPYRDMIGGLCYVQRRQRSNPVMGQMGIAVEGHEGVRPGRTNEESDRTHPSRRDLVPGVTLGLMSRYGPVKRWFDIYSRGPQVTHWKATVPYDWIKLSSSSGTLGPDGEDARIEVTIDWDQILDDFDQEVLIDVQSEEGDFEQIHLPITGRCIPGSFKEGFVEGDGYISIPAAHQALQGLRALPECGRTPEGAIVLVRGTKSAELAYKFYVFSQTASPSVLLYFNMTLDLDPADPMSYDVQVDGGPLQTHRLSPKTNDLPEGWFYAVQDCAWLRKHDLGENGLGAGEHSVTIRLKHSNLIFEKLVVDLGGVRESYLGPPLSVFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGJ8</accession>
    <name>A0AAD8UGJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_628315</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362788.1">
        <property type="nucleotide sequence ID" value="XM_060508694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGJ8"/>
    <dbReference type="GeneID" id="85392593"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF64">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="69"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="493" mass="53249" checksum="66E66A37BE361CEF" modified="2024-05-29" version="1">MSHDEVKQSEKPEPSSNGRPENPDLVPTTSNAEKSGSIVPAVDVDDAGLSRQDTEAIYNRFTPAKKRLVTAVVACGGIASTVSSLLLLAAIPEIAADLNTTGTTINVSNAIYVLFMGICTLFWGPISQVYGRKWPCIISACTFFAFNVGTALSPNLAAFFVFRMFSAFTGTAYLVLGSSCIGDIYKPTERGTALAFFLNGTLIGQSFGPFIGGVMVNFHSWRSLFWFQSALAGLTAILAVAFLPETSHRLRSDELKGLSTKAKVAQVLDWANPFRVLALLLIPKLFVAGMAASALVWNMQALLTPIRYVINPRFHLTSPLESGLFFLAPGCGFFFGTYAGGRWADRTVKHWIKIRGHRVPEDRLRSSFVAMGAVIPICIIVYGWSIEKAVGGIPLPVICMFIQGFAQVIAFPSINTYCLDVFKGRSAEVIAGNYFFRYAIAAVGTASCLPAIQSIGVGWFSTITALFVFFAAVAVYCVVIIASKKDAKVNEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGL4</accession>
    <name>A0AAD8UGL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_654817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361395.1">
        <property type="nucleotide sequence ID" value="XM_060510754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGL4"/>
    <dbReference type="GeneID" id="85394653"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032131">
        <property type="term" value="F:alkylated DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000004">
        <property type="entry name" value="DNA-3-methyladenine glycosylase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="5">
        <location>
            <begin position="210"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1719311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="43321" checksum="13E7AA656370EA5F" modified="2024-05-29" version="1">MTSRRSARLSAKTDIKIPPPPRIATPPVASPAPKGRKRKAPAEPALTDPAPSSDPVTPPRKRVSKTGPVTPAPPPPITPTPSAVGLIAERVNGTVKKPKTKAVSRLADPKLTNAPVISPETSRIIASRSAEAASPSKAPTGSVPARGEGTGGGSAKRTTTDNILEEACRHLIEVDERMKPLIEKNYCRVFSPEGLAEKVDPFESLCSGIISQQVSGAAARSIKNKFVALFTTDEEPEIKIEAAESTVSGSSSNKFPQPSGVAARSIENLRTAGLSQRKAEYIKGLAEKFASGELSAQMLADAPYEEVRDKLIAVRGLGLWSVEMFACFGLKRMDVFSLGDLGVQRGMAAFAGRDVAKLKAKGGGKWKYMSEKDMTEMASPFAPYRSVFMWYMWRVEETDISTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGM9</accession>
    <name>A0AAD8UGM9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_367827</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363972.1">
        <property type="nucleotide sequence ID" value="XM_060502620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGM9"/>
    <dbReference type="GeneID" id="85386519"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000457">
        <property type="entry name" value="rRNA processing protein Pwp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001345">
        <property type="entry name" value="WD40 repeat-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="271"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="407"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="501"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="501"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="60288" checksum="A7F91AD8DE2D8C1F" modified="2024-05-29" version="1">MSMITTSTWVPRGFAAPFPSKYTFDESEYERIAELAKLQLDDAEEDLREAQDEEEGADKPADEDATTGASGKKAEQLPCRVNINDDDLKEYDLEHYDDTDEEDEERVGQGEGMAMFGNIKSLAYYESNKDDPYITLPANGGPDDDDEDREDLQILATDNLLLAAKVEDEMAHLEVYVYEDAADNLYVHHDIMLPAIPLCVEWLDIPVQKAGVDKDSTANFVAIGTMDPDIEVWDLDTVDSLYPNAILGQAGEGSEEKKKQKKKKKAKKANDEYHVDAVLALAANRKHRNLLASASADKTVKLWDLHTAKCAKSYTYHTDKVCSLAWHSVESTVLLSGSYDRTVVAADMRAPEAKAPRWGVESDVENIRWDPHDPNYFYVSTENGIIHFNDIRNAPSTPEATKAVWTLQAHDESVSSFDINPIVPGFMATGSTDKTVKLWNIQASGPSMVVSRNLDVGKIFSTQFAPDSEVAFRLAVAGSRGTMHVWDTSTNAAVRHAFAERVPQKPEGVEEDRLVGVLDDDSSSSEDEGEEGEQDGDSMDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGT4</accession>
    <name>A0AAD8UGT4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair protein RAD14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_411868</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362938.1">
        <property type="nucleotide sequence ID" value="XM_060502916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGT4"/>
    <dbReference type="GeneID" id="85386815"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21077">
        <property type="entry name" value="DBD_Rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.530.10:FF:000003">
        <property type="entry name" value="Dna repair rad14 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022656">
        <property type="entry name" value="XPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022658">
        <property type="entry name" value="XPA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00598">
        <property type="entry name" value="rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05181">
        <property type="entry name" value="XPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00753">
        <property type="entry name" value="XPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="XPA C-terminal" evidence="13">
        <location>
            <begin position="240"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="75"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1722883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="396" mass="44073" checksum="B3EDD2910A6AE429" modified="2024-05-29" version="1">MVRPLTPPPNPATAPLPARTPPTPAAIRRMEESRLKAKAIRDRRDAELAASGAITTPKTASGFVATNDVHITNAGASQATDISRKRPHSSISTTNPSAATESHPSTNRDARDTNAAPRPARNFAKFVDYNMSAMTDTKGGFLTAEDDPHNTALVPKVKPGGPPQDEKPKGMSSQEWERLQLLKKLRRQKAGPFEPGLSVLADATMRKKCADCSSYEIDFVWDEIFGIQVCHACKEKLPDKYSLLTKTECKEDYLLTDEELKDADLLPHLSRPNPHKSHWHDMMLFLRMQVEEYAFTTKWGSAEKLDAEFAKREADKKRRKEAKFRDKLNDLKRKTRTEAIRRQQAITAAGAGPRKFGDSVGGGKHVHDWGRAVENEEGTTVKKCNGCGMEVEELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHX8</accession>
    <name>A0AAD8UHX8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_731246</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364306.1">
        <property type="nucleotide sequence ID" value="XM_060512866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHX8"/>
    <dbReference type="GeneID" id="85396764"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041897401" evidence="8">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="25"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="26413" checksum="809C48EAB34B3ECE" modified="2024-05-29" version="1">MHSRIVSCMSLFLLAAIASAQFEDPEHPYVPPAITDRRSPCPALNILANHGYINRDGAFISSESATVAQMQAFNFSRAVSAGPVPAALKYSTTGVNGTFHLDDLAQKPLDHDGSLSRGDLALGDNLRFNRTIWDSFVARLPDEFVTWKQAAEAGAARLEDARKENPEFTLDAAGVAATVEQMSGLLAAFGGSVEDGKARRDWINASFVEERLPWSLGWRTSETVLEGAAFGPMAKALREYAPGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI04</accession>
    <name>A0AAD8UI04_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_721816</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361866.1">
        <property type="nucleotide sequence ID" value="XM_060512414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI04"/>
    <dbReference type="GeneID" id="85396312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1720355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="50086" checksum="6A514D68B68EA59F" modified="2024-05-29" version="1">MHVPTQYPPNMLIDDDFTFLPYGFASTFAPELIDFNSLDVLSENILSNTRMSFLVPESLEPRSAEIISGLQELHHTLVATNQWYDGTFDLDTANSVFSAGNLCQFAATYFRVSHLDFPIVHRPDFGSDYTTKQLLLAVGLSGSLRSPPSDDALAARGYLTLAEEYIFRCLERLMPPGSAPEFTHELQETLQAALMIHSVQFFRNDVASRRKNRTQRLPQLVSAVRVLGLAQTKHAPIFQYEEFVRNESKIRLAIWTALGDWQQCGMFNTPPSMTPAELTCDLPSPLELWDAKDAAEYYEAANALGADGSRRICSVKQCTDALMAENWVGMGSFPFQDISGSDLQLLIFALNGMLASANLMGVLPACAPALLRAVSRWEVMWDMIRGRMEPAAFEKAGMIRYNSELCWIARKLVHVSISGDRSSAYMQKVGHDSLVQLHEFVRQYRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI29</accession>
    <name>A0AAD8UI29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain-fatty-acid-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_721734</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362100.1">
        <property type="nucleotide sequence ID" value="XM_060512408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI29"/>
    <dbReference type="GeneID" id="85396306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000008">
        <property type="entry name" value="2,3-dihydroxybenzoate-AMP ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF30">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="46"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="508"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="613" mass="65920" checksum="B698866EEBA455AB" modified="2024-05-29" version="1">MFPVRSGYSPARVLRISCEPLLLTQTIPQHFSQIVSQHGDLPAVTARSPTPNSSSAFPAATTTTLTYAALDALSNTLAHGLRSLGVRKGDRLAVSLGNGAEFAALTYAAFKLGAVLVPLNPGFNAKQVGAALRHLGVEVLVIGKVTDLPYKPCRGRSNLELLRTLVPDLDKGGGVVESEVVPSLRKVVVLDNAGFHPEVKFAGGFKALTPYEALLESGDAMRAVVPDAPLRPEDTINIQFTSGTTSQPKAAMLTHTSILNNGHLIAQRMGLVPGDRIVVPPPLFHCFGCVLGYMATATTGAGILFPSPAFDPSATLKMVADFDATGLYGVSTMFVAVLEALAGGGVVKKEDMPTDLRKGIAAGSSVPESLMRRLYEVLGLRDLVICYGMTETSPVSCMTAPDDGFDKRTGSVGRAMPHTAVKIVDPADRGRIVKRGERGELAAAGYLVMKGYWGDEERTAEVRREEEDGRVWMYSGDEARMDDDGYVEITGRIKDLIIRGGENIHPLEVENCLFQMEGVKEVSVVGVPDEKLGESVAAFVVLKKGWKGESGDDAAEGGKVITRDEARAWVREHLSSHLVPKHVFWVDDYPKTPSGKIQKFKLRDMAKELEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIF5</accession>
    <name>A0AAD8UIF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_754668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362121.1">
        <property type="nucleotide sequence ID" value="XM_060514505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIF5"/>
    <dbReference type="GeneID" id="85398403"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="17753" checksum="5DE0D32CE4BFD713" modified="2024-05-29" version="1">MYQQAKSNKSTSKGGSASMNQQTQLAREVLDPAHHQVKRHGLSRSEASIVDDPPQSNHLSSKKSKSRRNMVDVDRPWPRGKEAQEARLGTFSMPVDASVHDPSQRWYYDDMADQPYNAIGEVEMPARNSDEIPTSGEDDGVWPYEAVTSSGMVWYGSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ30</accession>
    <name>A0AAD8UJ30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_721395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362508.1">
        <property type="nucleotide sequence ID" value="XM_060512381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ30"/>
    <dbReference type="GeneID" id="85396279"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051178">
        <property type="entry name" value="TfdA_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779:SF3">
        <property type="entry name" value="(3R)-3-[(CARBOXYMETHYL)AMINO]FATTY ACID OXYGENASE_DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43779">
        <property type="entry name" value="DIOXYGENASE RV0097-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="6">
        <location>
            <begin position="136"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="30296" checksum="F2408467021CC09B" modified="2024-05-29" version="1">MPITELHTKELSPSFGIEAHNFPLQPDTLNQSARLIEDLIKKASFWGSLLGLIHISLARRLGELDDFKPYHRAGRINRLQYDELFDVGNIEANDSIVDPKFPRAPDWAGQCPLPPELTEKDYVACHSILHIKKFAAPEHFANIEPADYPMVRHKLVQKHKPSGRMNLYLAMHIPHIENLVPEGSKTLFEKLFDHATQEKYRVVVEWEDVGDMVVWDNTCTMHCAMCGQFAYRYRRDMRRVTVHDGSSQAWGLEERTDVRQGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJG9</accession>
    <name>A0AAD8UJG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_653578</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat striatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362939.1">
        <property type="nucleotide sequence ID" value="XM_060510629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJG9"/>
    <dbReference type="GeneID" id="85394528"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013258">
        <property type="entry name" value="Striatin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08232">
        <property type="entry name" value="Striatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Striatin N-terminal" evidence="9">
        <location>
            <begin position="27"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="791"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="588"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="718"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="248"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="589"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="870" mass="93485" checksum="6265E86BFAC5C680" modified="2024-05-29" version="1">MGGPGGNEMGGAMQGNGGNQPHATEYTLQGVMRFLQTEWHRHERDRNAWEIDRQEMKARIASLEGQARRADATQKALKKYVAILEKKVKDQAAQLKGGAKAGEDTAKAEKDRAALVQEKLRPSSKKPFDAHGGELDVEKADDESQRADLKSFLDQCQAEFTYLMITPANPLPPRDSPPLPILEDLREGEPFGVPGGKPFQEPPFPFASSSLVPQNHVREANRPPPAPNHAPPMQRSQPTSFQVKPVDQQQQLQQQQQQQQQQQQQQQHQPQQQHQQQMPPAAQEPAPPVMYAAGTEWPQPMSATGRMLDDNMQRPSHAVESISSVEPTEESQPSRPVPETDGWDFSDGSFADTNSSQSLQHITNRPDTDAFPTADNLPKSPNRGPSSHRRKGSMSRRRSADHELSLNSAAQKAETGNFKLRFGLRGHLDTVRTVIFSGGGSPGEPEICTAGDDGMIKRFHIPRADNHGQTNAASDLDVTANFSHRGHAGGVLCLTSWSPSPNFSTGGRAQGDGWIFSGGQDATIRVWERGRVDPKATLEGHTDAVWALCVLPTTLGSVFGQNSQYGSPDRILLVSGGADGSVRLWSVSAPPQLTSPQPGTNRAGPTGSRGRVRGNSMSSGSAFSSTPQPNMASSSPFNHTLVHNIKRPDGSDASPTCITSLSPSGDTFVVSYSDAAILVYDTRTGEQTGTMDSSETYDGSINTSVNAVVATTVGLEQPQGGLSEEDGSAGGGPTGGGGRSMAGSGVEGVIISGHEDRFVRFFDANSGKSQKLNTCEDDVLIKHPGQCTYNMLAHPASISGLSLSPDGRELVSAGHDASLRFWSLEKRSCTQEITSHRIMRGEGVCSVVWSQDGKWVVSGGGDGVVKVFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJQ6</accession>
    <name>A0AAD8UJQ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_620605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365221.1">
        <property type="nucleotide sequence ID" value="XM_060508205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJQ6"/>
    <dbReference type="GeneID" id="85392104"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000246">
        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050614">
        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF0">
        <property type="entry name" value="DELTA(24)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="9">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="55413" checksum="92C890E02C157881" modified="2024-05-29" version="1">MAGPIETEYRLIKHRRRVSIIAAKARRFARDGVKYRIYHKTTNSTRPSTRQADEIIDISGLDHVITVDHRGRRAAVEPNVSMATLVTATLKHGLIPAVVPEFPGITVGGAFSGTALESSSFRYGHFEKSVASLEVILGNGNIVTASTVENSDLFSGLAGSCGTLGICTIIEVKLVPARRFVELNYLPVHSAAEALNTIQSYTADTSPVDFVDGIMFGLNDGAIITGTMTDEKKQGMPVVRFSRAHDQWFALHVHGSVPHVRDTNCMVVPIKDYLFRYDRASFWMGVYGQNPDTFNGLTRFLLNPTVKAECLFAGIHHSRQNRTVFFQDITLPGNTVAAFLDWVNNNLGIYPLWICPVRVISDSRNRRRYHHMNVNVRLWGPKTIHGPDDNPRRDDPEAFERFIRDNKMIEQATRDLGGTKVVYGDNYYTEEEFWRIYNKEFYDELRDKWGAAGLPSLWDKLGNPNPTYKEQPSRSKAVMSVLLKRDYLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJU3</accession>
    <name>A0AAD8UJU3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prion-inhibition and propagation, helo domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_416379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362614.1">
        <property type="nucleotide sequence ID" value="XM_060502954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJU3"/>
    <dbReference type="GeneID" id="85386853"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1020">
        <property type="entry name" value="Prion-inhibition and propagation, HeLo domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029498">
        <property type="entry name" value="HeLo_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038305">
        <property type="entry name" value="HeLo_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14479">
        <property type="entry name" value="HeLo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0034">Amyloid</keyword>
    <keyword evidence="2" id="KW-0640">Prion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prion-inhibition and propagation HeLo" evidence="1">
        <location>
            <begin position="11"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="30303" checksum="EA6E7C3D059E254B" modified="2024-05-29" version="1">MELIPFSLAIAKIPSIFKECIECFHCVRLGPAFRQNFGLYIANLDGAYMQLNRWGKSMCFLDATFHGPKLYNKGKCKVKDKCMWKDDDIKKAEKWLNMIRAAFQNAKRISEQFKELHEDDDEASENLQFLDQDAEMQEADQIIKRLVLSIRKVTNHRRKKVPPSERQEGGAVAQAQWTIYRKSEFDGLVDSIRTLLDKLVILFPEFHHEQTTLCLEEAKKVGLGCFNKLAEVFGENDKFLYEAVMKITNEASRSRPPQHSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKH4</accession>
    <name>A0AAD8UKH4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_323035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364963.1">
        <property type="nucleotide sequence ID" value="XM_060502383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKH4"/>
    <dbReference type="GeneID" id="85386282"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF55">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="78"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="58300" checksum="7044A833552C5F47" modified="2024-05-29" version="1">MNPEKELLSATSAGPAPVSQTPGPGPDVEASHPAPGAVPDESHRRAGDDDALAMVGFHSQPYDPAVAARAVRKIDWFLIPAMIFGYGLVYYDKAILGSAVLFGMTTDLHLSVPLPSGPGVDTSRLSWATSLFYFGMLAGLYPMTYALQRYSLGRTLGTIVILWSSICMLTAAVTSYTGLYAQRFFLGFVESVIPTGFMCIVSGNYTQAEQSLRQSWWFSATGLFTIIGGALNYAFAQVRGGDLKPWQYIYLLAGCLTFLFGLACFLLPDSPVSAWFLTREERFAAVERLRHGQTGVRCTKFKPHQFREALLDAKTWLVALMMASAYTMNGAVSGFGPLIVSTFGYTSLQSILFQFPLGGLCFLVILATGYLGTRYTNVRIIMLVTCCLPVIAGCALIWRSDWTHHAAAPVVGYSITGFFGGVVSLVITLGMSNVAGHTKKSFMAGTIFAAYCVGNIVGPQLVKSQSKASHYPELWLGLIICYVICILASGALYYVLRKENKRRDALPVDEEERAKLAFQDLTDKENPYFRYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULB9</accession>
    <name>A0AAD8ULB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="17">Cytochrome P450</fullName>
                <ecNumber evidence="17">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="17">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="17">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_580325</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17 18">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="17"/>
    <dbReference type="EC" id="1.6.2.4" evidence="17"/>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363708.1">
        <property type="nucleotide sequence ID" value="XM_060505338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULB9"/>
    <dbReference type="GeneID" id="85389237"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000011">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000198">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000031">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 17" id="KW-0274">FAD</keyword>
    <keyword evidence="5 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 17" id="KW-0288">FMN</keyword>
    <keyword evidence="4 17 18" id="KW-0349">Heme</keyword>
    <keyword evidence="12 17 18" id="KW-0408">Iron</keyword>
    <keyword evidence="7 17 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 17" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="11 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="19">
        <location>
            <begin position="498"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="677"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="18">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1723653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1067" mass="118328" checksum="98F957FD9801A88E" modified="2024-05-29" version="1">MSETVPIPEPGGLPFLGNLNEIDSEFPLGSMMSLADQYGEIYRLRFPGRSIVLVSTQQLVNETCDEKRFKKSVNSALNQVRAGVHDGLFTAKMGEENWGIAHRVLMPAFGPLSIRGMYDEMHDIASQLALKWARYGPESAIMVTDDFTRLTLDTLALCSMGYRFNSYYSPVLHPFIEAMGDFLTEAGNKSRRLPLPAMFYSAKDQKFQQDIDTLRTTAREVLESRKEGKSDRRDLLTAMLEGVDPKTGKKMTDESIMDNLITFLIAGHETTSGLLSFAFYQLLKHPEAYRKAQQEVDNVVGKGQIKVDHMSKLPYINGVLRETLRVNATIPVFSVEAFEDTVLGGKYPVGAGETIINLLAKSQVDPAVFGEDANEFKPERMMDENFNRITKEFPNCWKPFGNGMRGCIGRPFAWQEALLVMVMLLQNFNFVLDPNYHFGIKQTLTIKPKDMHMRAILRDNLTPTTLERRLAGLAEPEKPAEHAKANGAAAEGESGMPLTILYGSNSGTCEALAQRVASDAASHGFRASKIDCLDSANGSLPTDQPVVIITASYEGQPPDNAGHFVAWIEGQDKAQSPLKDVSYAVFGCGHKDWVQTFHRVPKLVDTTLEQLGATRLAEVGLTDVSSGEVFTNFESWEDDILWPSLTNKYKTTSSADDSKTKGLGVVISNPRTSTLRQDVKEATVTKTATLTKGKSIKKHVEIKLPEDMTYTAGDYLAVLPINPKETVYRAMRRFHIARDAHLSIKTDGPTSLPVDTSVPANDLLSSYVELSQPATKRNILALAEHAKDESTKTELNRLSGDAYADEVSGKRVSVLDLLERHPSIDLPIGVFLSMMPPMRVRQYSISSSPMAYPNNVTLTFSVLNEPSLSGQGPYIGVASSYLDSLAEGDSLHVSIRPSHAAFSLPTDAENTPMVCVAAGTGLAPFRGFIQERATMLAAGRTLAPALLFFGCRSPEEDDLYRDEFDKWEEMGAVSVRRAFSRDCDKSEGCKHVQDRMWQDREELVDLWKKGSKAYVCGSRGVAESAKETMLKIKVEMEKARGQETDEESVKEWFEALRNIRYVTDVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM71</accession>
    <name>A0AAD8UM71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_627699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362990.1">
        <property type="nucleotide sequence ID" value="XM_060508651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM71"/>
    <dbReference type="GeneID" id="85392550"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="164" mass="18294" checksum="BEAB269EF81CA669" modified="2024-05-29" version="1">MVDFYVSFLGCIVAFENEALSILRFDDEDDHHRVAIVELPGLKTAEPQATGLEHVAFCYSTLADLLSTYQTHKANGIIPYWCVNHGPTTSLYYKDPDGNGVELLVDNFDTIREANDFMASSLFVENPIGTEFDPDDLIRRSAQGESESALKRRVEIGPRKAFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMB5</accession>
    <name>A0AAD8UMB5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA polymerase</fullName>
            <ecNumber evidence="13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_382166</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363754.1">
        <property type="nucleotide sequence ID" value="XM_060502713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMB5"/>
    <dbReference type="GeneID" id="85386612"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000005">
        <property type="entry name" value="DNA polymerase IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019843">
        <property type="entry name" value="DNA_pol-X_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF29">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY PROTEIN POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00522">
        <property type="entry name" value="DNA_POLYMERASE_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="15">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1723699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="600" mass="66840" checksum="BF93A841E61F012B" modified="2024-05-29" version="1">MTVLDFPSIYLLPTHLEADQLHELEGRIPSLTYDIREAEIIVGNIFKRERALFELRRKKVQTDPVDVAAVADAHLVTPRKRKRASSGSDSDSTVYTEDGQRFGLDTSQLAGTWPAPEKSSGNANTVKVVKLAWLQDSFAQGRVLPLHDYVLYVGIKKEEDRAPVTIRGSDILSRAVADSASQTQGSLLPQKKKAQSPTGMHRSVPSLVRQTTSENASTLKLPPVPQYLRTTYACQRSTPVDPPNAAFVDGLKTIRTIRRLGGDQIGVRAYSTSIATISAYPHEIASPQEVARLPGCGAKIAELWHEWKETGRLPEASEAQANPKFAVIQTFYDIWGVGDATARDFYGRGWRDLDDVVEHGWASLSRVQQIGVKYYDEFKLKIPRTEVESIADTILAHARSIHLDFQLVIVGGYRRGKQGSGDVDVVMSHPDESVTLNFVDKLVMSLEKTGHITHTLVLSKHNSERGQQPVSWKGNEFRGSGFDSLDKALVVWQEPEKGEKGPQEKPHRRVDIIISPWKTAGCAILGWSGETTFQRDLRRYCKKQKSYKFDSSGIRSRLDGSWVDLESSDLGRAPDMLTAERRVFQGLGLDWVPPEDRCTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMB8</accession>
    <name>A0AAD8UMB8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Histone deacetylase</fullName>
            <ecNumber evidence="2 9">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_622523</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 9"/>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364650.1">
        <property type="nucleotide sequence ID" value="XM_060508337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMB8"/>
    <dbReference type="GeneID" id="85392236"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000007">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="78"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1724595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="486" mass="54725" checksum="F9521DFDE43589D7" modified="2024-05-29" version="1">MDTDAYRFRPNYLPHRTDKDDIVEEYEPLGQASELDNAKYFAKCKRIAEESGITRPKGYNVSFHCNPEMEKHHFGQTHPMKPWRLTLSKSLIYSYGMSFAMDNYIARAATYEELNDFHSDDYLDFLGTVLPEPVPRDVENANPDLKFNLGGSDCPLFEGLYDYCSMSAGGSLDAARKICSNQSDIAVSWGGGLHHAKKAEASGFCYINDIVLAILQLLRCYPRVLYIDIDVHHGDGVEEAFYSTDRVMTVSFHKYDPLNFFPGTGGLDDNGPKNEHNPGAHHAINVPLNDGVTDDQYKWLFENVIGKCMEKFRPSAIALQCGADSLAGDRLGRFNLQVQGHGACVEFCKSFGVPMILFGGGGYTPRNVARAWAFETSIAIGCQDKIDPIIPTHAPWRDQFRYEELFPTLEQILGEPRVNRNTRKKLDEVLQHVTEQLRFVQAAPNYPPDLGGLRDDVEAALKEQREAENDAVRKQREEAVGQAMEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMI8</accession>
    <name>A0AAD8UMI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_617217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366178.1">
        <property type="nucleotide sequence ID" value="XM_060508016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMI8"/>
    <dbReference type="GeneID" id="85391915"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="71" mass="7738" checksum="6752DD84700E4230" modified="2024-05-29" version="1">MRVADGYLVYAVHTLSLGVSVAPITLSVSISLSLPCCRSLNVCFVGPVATQGARHTHTHYTAYVYALQRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMJ4</accession>
    <name>A0AAD8UMJ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_753195</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363874.1">
        <property type="nucleotide sequence ID" value="XM_060514323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMJ4"/>
    <dbReference type="GeneID" id="85398221"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000163">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000128">
        <property type="entry name" value="Serine/threonine-protein kinase ksg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="299"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="591"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="830"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="846"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="860"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="877" mass="95395" checksum="CA5145CB3705F797" modified="2024-05-29" version="1">MNGDLSLSRALGGLRIANPDDADASPSDSQDADAPSSTDRQPNHDIQRQQQYQLNAHTRLAPLDDPTTQPSPSPFGSTPTSDSLLPPISHTQSSEAPSPAYDGSPSHAEPRRTSPSAAMRADVYRQPVSPYSEIDRAPGNRSSVSPTARPVSALYSHQPVATEEGHPLHQPQGPSDRARHSAYGLLARQDSNNAQGYPGSSTPTREPSYRAPANPTRQSQLPPGSGSLPPRRSSKGMGGGYVSATAAPGGPQDPYGPEAPLPTSSEEWKDRGAAVGVRRETDSNGKTVIRHVKKGVRDFAFGRVLGEGSYSTVYLATDRQTLKEYAIKVLEKKHIIKEKKIKYVNIEKNTLNRLTEHPGIVRLYYTFQDEMSLYYVLDLCNGGELLGVLKKTGSFDLECTRFYSAQILDAIDYMHSRGVIHRDLKPENVLLDDHMHVKITDFGTAKLLKDPREAQNVGDSARGLPDSGRSEADDDNRAASFVGTAEYVSPELLTSKNACKASDLWAFGCIVYQLLAGRPPFKAATEYLTFQKIVNLEYDFPTAFPPAARDLVERCLVLDPARRLTVEHIKNHEFFDGQPFGKGLWRTKAPRLRPYNPTPQDPTVIQLNGVSNSPNSAAPPRSTQPQSLALNGSARPARIITELPPPTQLDIEWSPVLTKNNERILKLGDLMVVSSPLPSGHGKGGEHAEGHKKLSRFFGGSTTKKRQRLVMVTSSGRILLAPAGGEEKRAKQEISLLAPECTWRTQLDVKGQTVWCVDAGGVHYTFEEPKGSSSSSENGTAASDWIESLERAKELALSQNLSGSYAGDNGFDMPSTVSSPASTLGGRGVYPDSFSVSDRSGRNHLSKSQASLDDSASTTKRNRFSKRQSKNGLGQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMU8</accession>
    <name>A0AAD8UMU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_577769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364905.1">
        <property type="nucleotide sequence ID" value="XM_060505051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMU8"/>
    <dbReference type="GeneID" id="85388950"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="6">
        <location>
            <begin position="15"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="442" mass="48455" checksum="275640192B8428AC" modified="2024-05-29" version="1">MTAREEEDPSYIDYEAFLDPEFSPSSFANTLVLATNNPNDAPLDLSTPLSRVLFDTQEIDSHIDVLTTKSAAPLLQYTKEQTTSSKRIISELDAQIKNLNDSYKQLEKEVIDKHAEAEEVRQVATRLWETLKLGRSVGRCLQLGRQLEVQHAEIAGSSVSAAAAAAGKKEDHRALVRCSHTILSLREVLDNTAPGEEGHGLGKVDAIRTLRESIITPVERSVKETAEKIIRDFAIPNSATFAQGEEVKARTVSAMVTLFLLSPAPTQKTERWTPQLLLQSLETYFRSALQSSIASLSRSLGQLPSLERTLAEISARCQNIVALELVLESTKLPAHPLVSAPQKQTNMLQPLLAYLETGSLPSYFWRTMAGNLGTRVQEIVNRGGVSARTLRSNRASVGDAVRECVVRGCQMPSALKGKGRGEGNWDREVAVMVGSVVNNLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN38</accession>
    <name>A0AAD8UN38_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_699398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364874.1">
        <property type="nucleotide sequence ID" value="XM_060511410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN38"/>
    <dbReference type="GeneID" id="85395308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041779297" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="60562" checksum="DA8F7D703151AAA7" modified="2024-05-29" version="1">MRTSSLIAGLTAVLNLPLISAYVPPKSHRSPLRRVAPGHAEVQAPPRAIMRRSSTLQYFNNKTSAFYVDGTGIPDVDFDVGESYAGLIPVDASKPESEQQKNFFWFFPTENPAGKDDVIIWFNGGPGCSSMEGFLQENGPFLWQYGTIKPVANAWSWHKLANVIWVEYPIGTGFSSGNVTATDNAETADQFVSFWKNFVKTFDLQGKKIYIAGESYAGIYVPYVGAAMLDKNDTTYFDVKGAVYYDPVMPYDDAMNFDHAAFPSFYRYWKNVFALPSGADKQIEQDAKNCQLDAYFNKHLAYPPPARPWPAANVKEECDIIAHFDAISTIINPCFNGYHILDTCPVLWDVLGFPSIMYSPPNTTLYFNRPEVRKAIHVPVDYPTWSECQDPVFVDYNDNYNGTEHEEKFQTLVERTNNVHVGSGLADYVIKPNVTTLAIQYVKWNGQQGFQKQPSEDLLIPTVNNVDENVPSWAGANVQGSVHTERGFTHSTAKISGHMVPQYAPSVAFRHSEFMLRRVDSLSAGAPWSVNISTTFQWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN44</accession>
    <name>A0AAD8UN44_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Trichodiene synthase</fullName>
            <ecNumber evidence="3 7">4.2.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Sesquiterpene cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_702395</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2E,6E)-farnesyl diphosphate = trichodiene + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12052"/>
            <dbReference type="ChEBI" id="CHEBI:15861"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="4.2.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Sesquiterpene biosynthesis; trichothecene biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the trichodiene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.6" evidence="3 7"/>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363440.1">
        <property type="nucleotide sequence ID" value="XM_060511458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN44"/>
    <dbReference type="GeneID" id="85395356"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045482">
        <property type="term" value="F:trichodiene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016106">
        <property type="term" value="P:sesquiterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010458">
        <property type="entry name" value="TRI5_ascomyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024652">
        <property type="entry name" value="Trichodiene_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06330">
        <property type="entry name" value="TRI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001388">
        <property type="entry name" value="TRI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01021">
        <property type="entry name" value="Trichodiene_Synthase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="(4s)-7-azabisabolene; inhibitor" evidence="8">
        <location>
            <position position="297"/>
        </location>
        <ligand/>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="45909" checksum="CBFDC6F9B978B7C0" modified="2024-05-29" version="1">MDTASFPTDCYLDAVVSFLSIINYNDTNYTHQDRVRNLHYAYAKAAKHFAQPTQQRLIKASPRRLQASLQTIVAMVVYAWVRVDPEVMADLSIHYTYMLVLDDSQDDPDATMQSFYQDLLAGKPQRHPWWQMVNAQFPTVLSHYGPYCGLNLVRSTTDFFQGCWIEQHNFQGFPGSYDFPGFLRRMNGLGHCVGASIFPKAQFDEKELFTEITSVISQMENWMVFVNDLLSFYKEFDEPRDQTSLVNNYAKCDRITLAEALNKLTRDTIRCSEQIVEVFADKDPSIADTLQTFCQGYVTWHLSDPRYLSDPRYRLRELVTSAAGGDSATAKEFRRYQAAGDLVGAVDPKEWAYPPVADLVEDHSVGEVVQVATPLVPKTSINASNTVGAVSKWAKKFWPQEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNP0</accession>
    <name>A0AAD8UNP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_611962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367812.1">
        <property type="nucleotide sequence ID" value="XM_060507692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNP0"/>
    <dbReference type="GeneID" id="85391591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="53" mass="5733" checksum="E63CA8A023C95FA7" modified="2024-05-29" version="1" fragment="single">MGQGKGTGRTGPSEQAAGPSLCRNRRGKSYISNGTSTRTLLAWYIWTWEMVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP00</accession>
    <name>A0AAD8UP00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_751656</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365670.1">
        <property type="nucleotide sequence ID" value="XM_060514083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP00"/>
    <dbReference type="GeneID" id="85397981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="140" mass="15661" checksum="959C4BC832B49F63" modified="2024-05-29" version="1">MSAQTMAQARAVVRELNGVVVSAGLMQKTVKVRVGGQQWKQKVQKMFTKPTHYLVHDPNSSLRTGDVVSIVPGWRTSPHKRHVVKSIIAPHGTPISARPPVPTEEERIAAKVQKREAKVERRETRRQEKSSKSTPEPDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP01</accession>
    <name>A0AAD8UP01_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_751088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366317.1">
        <property type="nucleotide sequence ID" value="XM_060514006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP01"/>
    <dbReference type="GeneID" id="85397904"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006838">
        <property type="entry name" value="ADTRP_AIG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989">
        <property type="entry name" value="ANDROGEN-INDUCED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989:SF16">
        <property type="entry name" value="AT02829P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04750">
        <property type="entry name" value="Far-17a_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="234" mass="26258" checksum="7A8E62AAD73211B8" modified="2024-05-29" version="1">MAKHQLQRLQSPSRTASLLLHVTGIVSFIASFNFLNGLTHDISMGFGGNYQHLTNIGLILSFVTFVIGLLADITLSPSLFAVKNALSTTAAPLEVLISILYWGIRSIDKRLLIPEGFELHWLPDVGFHLVPAVVLSLDLILFSPPWTIRAYSAMAISMIFAFLYWGWVELCFSRNGWYPYPIFDVLNTVQRVGLFTFSAALMTASTSLLKWVYGRFNGYGKMEKEAYKPLKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPD4</accession>
    <name>A0AAD8UPD4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CBF/Mak21 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_624401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364070.1">
        <property type="nucleotide sequence ID" value="XM_060508442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPD4"/>
    <dbReference type="GeneID" id="85392341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="319"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="546" mass="62430" checksum="D6FC9F82DBEA7CD0" modified="2024-05-29" version="1">MPAKVSGDGLKRKRVPTKEKSKKRAKSESESESEAESDESNDPQAEILLLENEILESKKHYNNITKLIQIAGTQEDEPEAPTLACVALCRVFVRLLSAGAFAFRPGQAEKEKVVVQWLRERYLEYKGVLASLLEEEDLASTALTLAMRCLKAEAQYFTEKEEYTFPHAFIEQIVRALLASDSDDVRVEFVEKYLTEYDDIRFFTLKAVKSIAENPGSLPKEEVFDDAFELLSYIGDVPKELGNFYAEKPKKKSHNVNSVHQHKKQGQDAWLAVLKLAATREQRKQILDVMSKEIAPWFIRPELLADFLTDSYDAGGSISLLALSGVFYLIQERNLDYPSFYTKLYSLLDRDILHSKYRSKFFRLMDTFLNSTHLPAVLVASFIKRLARLSLNAPPSAIVFIVPWMYNILKRHPLCTFMLHRETRDPAIKALMETQGVEDPFLADEADPMETHAIDSCLWEIVQLQSHYHPNVATIAKIMSEQFTKQSYNIEDFLDHSYSSLLEAEMGKQVRKPPVIEFQIPKKVFLPNEPESGVQDSLVAKLWNFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPG4</accession>
    <name>A0AAD8UPG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_741612</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364115.1">
        <property type="nucleotide sequence ID" value="XM_060513092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPG4"/>
    <dbReference type="GeneID" id="85396990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="461" mass="52272" checksum="9A6E69CB0A5E8A42" modified="2024-05-29" version="1">MLGALLVSGVVLYLLTASIYNAYFHKLAAFPGPLLGRYSLIWRIYHSQTGRFHYAIQEQHRKHGPVVRVSPNELSFASVESWKAIYGHRAAGAAPVIKSEFYDIYGAGFKSLCIGSERDPHKHGKMRKMLSAAFSTKMLLDQEDIITKTVDAFVYRLGEDAFQSEGLNMTKWFEMPHSWSEIIVSHLYFITLVDNLRRLPFVARVARVLFPSTLAVQNQNSQYSRKKVEERLSKKSNRNDFLSTVVKSYEVGAISEEEMTAHVSTLTIAGGETTATFLAAATYYLLRNPACLLKLQAEITKKFSSFEEINATAARQLPYLQAVISEGLRLYAPGSQGFPRLSPGMSVGDIYVPAGAEVFAHAWTLTHSEEYFSDPKNFKPERWLDAESTDVREASQPFSMGPRGCLGQNFAYMEINLILAKMLWQYDLELVGKDLDWEQESQLHVMWWKPALMVRFTRRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ67</accession>
    <name>A0AAD8UQ67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WLM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_614958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366902.1">
        <property type="nucleotide sequence ID" value="XM_060507875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ67"/>
    <dbReference type="GeneID" id="85391774"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WLM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="255"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="343"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="48404" checksum="D4FE7768892D55A5" modified="2024-05-29" version="1">MPEHDALILSFSHLSDFPRAPDALQTLKKVASLVKPIMRVRGWKVRELAEFYPDQANLLGLNINRGQRILVRLRYPNDRSLFLPTEHVVDTMLHELSHIVFGPHDGNFHALWNQLRDEHESLIRKGYTGEGFLSDGHRLGGGRIPMHEARRLARASAEKRRTLTKGSGQRLGGSGPSIGSDIRRTIVGAIERRNTTLQGCGNTNHNDREIQQISETATKNGFRTQAEEDAANEAAIAQALWELVQEEERQRYGGYFIPPTAQNPTGNGGGSVMGDNQNRSSSVPPPIPGPGTRPPSVPRPETRPSVMSAPVPQPAPQRGWTCGVCTLHNPSSFLCCDACGTERGQDPQRQVWTPNAEKRERERQRASMAATAKSTTQTATIDLTSSPPRASSSRKPGSSSLHPEPVKPLTWQCSYCGTMMERQWWTCLTCGVMKDNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US97</accession>
    <name>A0AAD8US97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_616444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366426.1">
        <property type="nucleotide sequence ID" value="XM_060507978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US97"/>
    <dbReference type="GeneID" id="85391877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295634" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8980" checksum="BD9D0544290C7F92" modified="2024-05-29" version="1">MTLSSYSLLTILISTLVTASIPYSVTPDSRSLDREWTRRRSRYAQIDTNQRHYAITNIPLSCELRQCLPGPSPLTRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUD2</accession>
    <name>A0AAD8UUD2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-threonine rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_224211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367324.1">
        <property type="nucleotide sequence ID" value="XM_060501761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUD2"/>
    <dbReference type="GeneID" id="85385660"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF4">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042044304" description="Serine-threonine rich protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="32014" checksum="E7BE7BF1AFA452E0" modified="2024-05-29" version="1">MKFSAVLALSAAVMASAKSVRNHYPVRRDGHKKGEKGQAQAGQIAGLPAGMTGFGVSNSQVTEVIIIWANPGAGAPTININPPAGGAAAPPAAAPPAAPAAPPAAPPAAPPAAQQTHQVMVGGAAGLVFVPDQIKANVGDMVVFTFMSQNHTATQSAFATPCDPLAGGMNSGFMANPNNSVSPPPQVAMQVMVSEPLWFYCAQANHCGKGMTFSINPTAAKTQAMFQSMAIAQKGQGAGGAITGGTPPAAAPAAPAASAPAAAPPAAAPAAPAAPAAGGEIQQGTGQINGAGACVCSVTCSSGSFPAVGAQGVGSFGGMAGSLPMAMMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUS8</accession>
    <name>A0AAD8UUS8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginyltransferase</fullName>
            <ecNumber evidence="2">2.3.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_717238</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the R-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.8" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368144.1">
        <property type="nucleotide sequence ID" value="XM_060511924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUS8"/>
    <dbReference type="GeneID" id="85395822"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end aminoacyl transferase N-terminal" evidence="6">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="7">
        <location>
            <begin position="139"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="425" mass="48893" checksum="ADCDA4B704EFF092" modified="2024-05-29" version="1">MSSRVSRFSYYAKSTSLTPEYYQTLLDHYWRRSGTTLYRPDQLHACCVHYTLRLDSTQFKPTRDQRQTVNRFNKYLTGDAYIKEAARLHPRSREQAKKRDSEFGLIERVHEAEYDFLQLPPEPAHVFTVTLEDDVFTEEKYQVYENYQRVVHGEEPADITRRGFQRFLCESPVQRKTITAADGKEQKLGSFHQCYRLDGKLVAIGVLDLLPHCVSAVYFLYHESIHKFAPGKLGAIREIALAQEDGYRYWYPGFYIHSCPKMRYKMDYTPQYILDPETLAWDLMDKRVTNLLDNKPYLSLSKEKADGQAAEGAKNDSDQPAAGQEESTKDPRDKADDDDDDTFLFNTGMPGIMSLDEIRSLEEMDHIKLRIDGSGLLFETGDLVAWERQDVGVSGCLKAGIAELVAALGPELLEDMVVDFWNPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWK7</accession>
    <name>A0AAD8UWK7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_126453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368449.1">
        <property type="nucleotide sequence ID" value="XM_060501187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWK7"/>
    <dbReference type="GeneID" id="85385086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="21"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1728394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="38619" checksum="1ED1928305804022" modified="2024-05-29" version="1">MAATDYKFEGWVGLDEKSSEGNMVWQEYEPKPWEENDVDIQITHSGVCGSDIHVLRSGWGPAPYPVCVGHEIVGVAVRVGSKAVGGIKVGDRVGVGAQSDSCLGRQGPCEPCETKNEQYCPKSVHTYGHFHYNGGKAMGGHSKYHRCPSHFVVKIPDGLESAYAAPMLCGGVTVFSPLKQHGAGPGKTVAINGVGGLGHMAIMLAKAMGADKVVGISRKGDKRDEVLKMGADGYIATSEEPDWAKTYANSFDIVISTVSSAKVPMQDFLNLVKLDGSLVQVGLPDDGAYTISPVPMVMRRVKFTGSLIGSPHEIREMWELAAEKGVKPWIQVRPMSEANQAIVDLEEGKARYRYVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXW7</accession>
    <name>A0AAD8UXW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_749078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368735.1">
        <property type="nucleotide sequence ID" value="XM_060513716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXW7"/>
    <dbReference type="GeneID" id="85397614"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="115" mass="12357" checksum="44D1BD9719FAD403" modified="2024-05-29" version="1">MSAATGRIATRTLVLPAGLRGRPLQRAAFSTSPYRTAGGTAQSKNGNTNANINGNKAGGEDPLEIPAFNLRHISSSPRARFWLITGFCVIASVEMYGWYNFGPKILGWEGKGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8G2</accession>
    <name>A0AAD8X8G2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_657494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358314.1">
        <property type="nucleotide sequence ID" value="XM_060510966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8G2"/>
    <dbReference type="GeneID" id="85394865"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08734">
        <property type="entry name" value="RGS-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63195" checksum="FEEADF10C4A96FE8" modified="2024-05-29" version="1">MESSAEATPTPTAAAAAPAFNTAPVAVFWLAWGGFWTVLLLCGMAFLFVNRKMPFLRIRGLALSFGAVTMLHLYWLSVQIGLAIGQFVPDGAEFWVMGLYLPFGIALFHASNSRFLHIAKAQRKYADKPLTQSNSQLDTSNGPDKTLTGKFRKLDYTTKMLAVVCTGMLVQLLLTVVMYLVSRKYHPSFGVPGTEVTGTPAQQKVEMGRGWEWWPSVFWQFLWAWLVAPVILWKSRGIQDTQGWRLQTIACSIASLHATPMWLVALYVPAMAPVNAYFIPPQWTLRQETLESIAVWEAKNKARAGRDSVITGSTKVGSQASVTWKSLAQLEKDTSQAESVYTMGALEYVLDKNPEPLRKFSALRDFSGENIAFLSAVAEWKSSIPQSPGSSHRSVEISRERFNRALRIYTEFISPYHAEFQINIASQDLKRLEGVFEGAARILYGDRTERFSDPVVPFEDNSWGGPESTAGGSEMSCVSRDGSGDPIADRVQYWGEIPEAFNAAVFDDAESSIKYLVLTNTWPKFVKERRYSLDSEDSGETVETFQSSSTLSSRVKKYFRTMKIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8W4</accession>
    <name>A0AAD8X8W4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Myosin-like coiled-coil protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_591404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000171">
        <property type="protein sequence ID" value="KAK1710339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358809.1">
        <property type="nucleotide sequence ID" value="XM_060506431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8W4"/>
    <dbReference type="GeneID" id="85390330"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.950">
        <property type="entry name" value="Methyl-accepting chemotaxis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="355"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="50494" checksum="59BDC778591A36C6" modified="2024-05-29" version="1">MSNGQDGHAHPPAASLKKGKQKKAVDSNESAKLLAQRISQLEQESAGEKDQEAEIEREVKRANRDLAQQVAKMSDLQKIEHLTRRSSELLADMRRVERENQKNKKRGDALQKEKDANRTELSKTVGLKEKLEKLCRELQRDNNKYKNENKTLQDNLKHNSSAYDEKHAALLAKLEGIQEEKDHPRKQVVDMSVDTLFKNRFKSFIEQYELRELHFHSTMRTKELEVQYNMARYEREKKLAEAESTRARNLQAQVQTFTKTETELRNQLNVYVDKFKQVEDTLNNSNDLFLTFRKEMEDMSKKTKRLEKENETMKRKHEATNANIIRMAEEREDWRKKAAEAIKRAEKLRSIIEQMQQQGRKVPPGAAATLESCYSDSNGHMDGDGSDYSDEEEEGEEDPSEFDDDTEEEPQPGEPEPPRPYGPERPPVPQAATNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9Q7</accession>
    <name>A0AAD8X9Q7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLAC8 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359739.1">
        <property type="nucleotide sequence ID" value="XM_060506220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9Q7"/>
    <dbReference type="GeneID" id="85390119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="145" mass="16142" checksum="6075CC96D0665044" modified="2024-05-29" version="1">MQQEYVQGANVQTQEWQSSLMDCGPCDTCIVGTCLPCLLLGKTSERMRDPTMQTYEAINTDCLLMCGITWFTGCGWIYAMMKRGEIRERFGIKGSGGSDCCVSYWCGCCALIQQDKEVQARLSTGPIVQGYQPQKEGMHMPPQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA77</accession>
    <name>A0AAD8XA77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_724018</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358826.1">
        <property type="nucleotide sequence ID" value="XM_060512617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA77"/>
    <dbReference type="GeneID" id="85396515"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF37">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042004448" evidence="5">
        <location>
            <begin position="20"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="6">
        <location>
            <begin position="80"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1710547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="504" mass="54584" checksum="B87B659125E3B0D1" modified="2024-05-29" version="1">MPSISLAAAVAGFVTLANASSVLLRGGTIIGFDESSNSLNVIRNGSLLITDDRITSIYTSDQPLPQSSNDTEVIDVTNKIITPGFVDTHRHGWQTAFRTIASNTSLAEYFTRYGEYAAAGFLSADDVYIGQLAGLYEALNAGVTTTLDHAHHTWSDGTSEAGLKGSIDSGARVFWSYAFHNVTNYTVSEQLENFRNIATKAEFDGTPTTLGVACDFFGTDGVLADINAVVDLAKEFNVSVITTHSLQGPWGNTNSPEDVHAIGVLNTSIPVVFSHASFLTYKGASLLRSTNQYISITPESEMHYGHTHPHSHLIQDQGSLGVDTHFTFSTDILTQARLWLQSTRRLLYQQVLANWRVPTSTPMTVNQAFLLATRNGGLALRRPDLGVITEGAKADVVVWDGESPALLGWVDPVAAVILHASVADVEHVLVDGKFVKKDHKLVVPDYADVKTRFLESARKIQQTWRDIPFSALEGEFSSSEAPYEAPLSVDVLPGGESGYGTTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAK6</accession>
    <name>A0AAD8XAK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_655870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360217.1">
        <property type="nucleotide sequence ID" value="XM_060510825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAK6"/>
    <dbReference type="GeneID" id="85394724"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="27803" checksum="3CA4AECBD135E2F6" modified="2024-05-29" version="1">MAQEGRRRRRRAHRRRQQDDNSEGHPKRFLLCIPWPQSRRMRSQILRCFISGGFLTLLLAVYLALSLTQNIRSSEFTVLLILIILFVTIFFCHGLIRLCMLVIRPRVDDEARPPMPQLLAPGGYAVPREPIRVVLARDEEEQGEVSEAVLAKPPAYGLWRESVRVDPNRIYWQRNPNAAPNEGTSSRGDSSTGPRPPSYASEDGVSYVVEARPRSMAPAAMTDVLTPLPTHPSERGRMGEHRSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAM2</accession>
    <name>A0AAD8XAM2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_722705</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360684.1">
        <property type="nucleotide sequence ID" value="XM_060512497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAM2"/>
    <dbReference type="GeneID" id="85396395"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="87"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="462"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="483" mass="55303" checksum="CB304D8886F8894A" modified="2024-05-29" version="1">MATATATRKRSRDDFEIHQDPPHARTEDTEMMAESEQHTEEVEDEEEEVEVEEPSDESSDEDEVVDTGVQRDMDRLQDTFPGFPQRYRLIKRIGEGTFSTVYKAEDLQYEFYDNSWDLEEKDNLGAKWTSPPLKPNASNTSVTRERRRARYVAIKKIYVTSSPNRILNELELLHDLRNCAAVCPLITAFRSTDQVIAILPYFRHEDFRDYFRQMKVSDMAIYLRSLFTALKAVHEHKILHRDIKPTNFLYDPQSRRGVLVDFGLAEREGSDSKPCLCHESKDVRKQRITNSAASQNGPQQGYPKTDTRPSRRANRAGTRGFRAPEVLFKCTEQTTKIDIWSAGVILLTIMSKRFPFFNSADDVEAMIEIATIFGVKRMKQAGLLHGCMFETNIPTVGNAGFSLGKIILWSTCRTDGGKDGQPGIPLTDDEKLAVDFLERCMELDPARRISAKDALEHEFLREPKLKQSVETDHDDDEMDMLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAS8</accession>
    <name>A0AAD8XAS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_589945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359471.1">
        <property type="nucleotide sequence ID" value="XM_060506283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAS8"/>
    <dbReference type="GeneID" id="85390182"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF102">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="43135" checksum="3F0E688533CBA188" modified="2024-05-29" version="1">MEASTGIDGRHEAPAEERNEPNEEKSSIRTAQSTIDDDRSSRLTSSALDELNASHIDSSTSLSLSIDTDISDADSAMGIDVGRASSSASVASSVYRFVEEFGRTYHAYKEGKYFLPNDEQEQSRLDLQHAIALRIFNDKLGLAPVSNPHRVLDIGTGTGIWAIEFADRYPASDVLGTDLSPIQPEYVPANCHFEIDDAEDEWAFSQKFDYVHGRYMCTSIFDLPKLFGQIYENLNPGGWVEFQETVIDFKAVDGSLEGTALRRWNDHLLEGIRKAGRDALSAFEYARHMTDAGFQNVEQKRFAVPASPWAKGRNQKILGAMQMTNNLEGVQGITMKIFCQVLGWTREDAELLLMDVRKDMADKNIHAYITTMSVWGQKPQEAGRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBW5</accession>
    <name>A0AAD8XBW5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_743934</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360626.1">
        <property type="nucleotide sequence ID" value="XM_060513146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBW5"/>
    <dbReference type="GeneID" id="85397044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000001">
        <property type="entry name" value="Uracil permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="58241" checksum="584E8FA49B472F30" modified="2024-05-29" version="1">MGLRKRLELRSESADLGTEGGRLSNKDMDPIPMGSPERTWGWPSLLGFWIAEAFSISMYQVSSTSVTKGLNPGLAILAVFIGHVLVCIPAMLDGYVGCIFGINFPVFTRASFGLRGSYGAVFVRGVVACIWFGTQSFQGGQCLQVMISAIWPSFNNFPNHLAESAHVTSSELLCFFLFIIIQLPLLWLHVSSLRYMFMVKTVIMPIFGLTLFIWAIVAGKGFGPTFSKPTLIKDGTPAIVVFFQCVTSAIGPKATLALNMPDFTRYAKEPRQVFWTQAVGLCVLVTMCGVLGATVSSASEVIYGKVTWNPLEVARLWENRAAQFFAGLCWAFAVIGTNISANSVSFSNDLALWFPKYINNRRGAYICAVFGVCAVPWYIQYSAKSFSSFLGGYSLFLGAIAGIIITDFWICRKRIMAVSSLFDPRGIHYYTFGVNPRAVIAFILAIIPNMPGLAAACGAKGVPKGAIYLYSLSWLVSTLVASFTYWLSWKVKPFPVDDSREQLYVDGYPTVEDSVGSENGLEGKDRDVKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD57</accession>
    <name>A0AAD8XD57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine dehydratase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_93749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359500.1">
        <property type="nucleotide sequence ID" value="XM_060516017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD57"/>
    <dbReference type="GeneID" id="85399915"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="3">
        <location>
            <begin position="315"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="448" mass="47975" checksum="18F3846E1B5081A1" modified="2024-05-29" version="1">MALPQRIAPSTEALRKFYVGKDVNDVPKPAVVLDAAKVRTHCRSMLEAVDDLGVGFRFHVKTHKATKINCIVSTVAEIEHLLPTFKEYKHASRHVNVLYGVPLLGSQIERLAFLSEELGKDGLTVLVDHPSQLGSIRRLHDLSGLPVGVYLKVDTGYHRAGLPATALNKGGLLEQLTQLEAEGKATLVGLYSHSSLSYKDDTANQAMHNLAGEIEGCLEALHANESLLAANTSREITISVGASPQVTAIENLTGAAAVSGSGEARLRTAISKVQDGSPTVKSTLELHAGVYALLDMQQMSTRSRTALGSHEDEVAISVVAEVCSVYNDGEREKPEALVAVGVLGLGREPCPSYPGWGVVGRQPGFEAAGGRRLIVDRISQEHAILSWEADAGAKSDLPQIPLEVGQSVSIYPNHACVTGALYGWYLVVDSSKSNKTKIVDVWVRGSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDT2</accession>
    <name>A0AAD8XDT2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucans biosynthesis glucosyltransferase H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_720599</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family. OpgH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363517.1">
        <property type="nucleotide sequence ID" value="XM_060512290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDT2"/>
    <dbReference type="GeneID" id="85396188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050321">
        <property type="entry name" value="Glycosyltr_2/OpgH_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003962">
        <property type="entry name" value="PRK05454.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867">
        <property type="entry name" value="CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43867:SF5">
        <property type="entry name" value="GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="13">
        <location>
            <begin position="165"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="61997" checksum="8365DCCF722FDEB1" modified="2024-05-29" version="1">MASDLKHTLLDIVVVLCGTICIPWPIVCFWNSAIGLCIILFGNAERSVYPYFRPRGPLSKLRSTTALTIFMRNEDPGPVFDRLYAMYESLQQTNCLKHFRFVLLSDTGHVDVVRSEEEVFAQHAVSLSEGMAKSLLYRRRDRNTGYKAGNLKDYLDNHSKEDDFFVTLDSDSAMSGDLLVRLVSSMEENPLIGLLQTIVIGMPAFSAFTRLFQFGLRHGVRTYNMGFSWWAHDCALYWGHNAIIRTDAFHKHCMLPKAPWRAAAGCHDLLEAMFMRRGGYEVRVLPIETESYETNPPTFLDFLRRELRWCQGTMQYWFMLSEPGIHPISRFQMCQTLTTYIGQACCVLMTLACIAKEVIGEPSVTKMSLVFSWNPHLVLTAFGIFPKLVSVFEVVITSSRRYGGSFRCILSTLMELFLMTFIAPITALAVAIFLCGLLRGKVIKWDGQNRDRLGLSWRDSFRVLWPQTILGLAVLLAARGTAELAWAVLSAVGFLFAIPVAVLTASPRCGNAILSMRLFEIPGETELPLLLSKLIPSGYSYLNHITKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE32</accession>
    <name>A0AAD8XE32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor Opi1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361388.1">
        <property type="nucleotide sequence ID" value="XM_060514599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE32"/>
    <dbReference type="GeneID" id="85398497"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013927">
        <property type="entry name" value="TF_Opi1_Ccg-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08618">
        <property type="entry name" value="Opi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="687" mass="74693" checksum="4DC78D73966EDF67" modified="2024-05-29" version="1">MDLSQSMSQSQNHMLHGPAPGDRQLPPSSSSLAHTHHIRPPASASASASASASAATSTSASTSIPTASQPNKHVLSHARFDPTHLPSQLPSYAPPSYAHAQSHDPNLLRFPDAPTTELAPILPAAKHNDNVGHNLPSLSSVTGPPPPRFTSIAAQSQPIEKQQQHQHQHHQPQSQPQPTTSSLKRSSTTTVPLTHWPSLNPLTTYYTPSHAQPADSPARMDLDVVSNSAMSAASPDRFYEGRAASVSLDDPDVRMAAEALGDLRADFINSPPARHTPLPRASPAVSITSNPQLKSEEPLFSLLTTSHPLLATTIEGATSAYNNSKNFSPRFKSSAEYVEGYLTPIANTVGTVGRKTGVEGGVRWFLGAGRRHQSNDIEAADGGSHKRRKVDTGEDLARLMIDAQSNVMPDVDSPRDPYVFKHDRRLSRASTIDTLPAYDDYRSPAYSENEKAERPTSSNAAWQSRLIMSTSGLSVAMSDESLRSLKYCLRWLRWANEHIGGVINNLKTTLEQFEKPGQPQQEEQTAATNDGDHVMADSQPEPMSEQERTILAAKIASLKGDVLKTLQNVIVTVSKYAGGALPENARLLVRRHLTTLPQRFRYASMVEHQQGEKVGDQEAMREGAHRVLVLAKEGLDMMSQVSGVLDGTIVSAEEWCERLGKKKRDHQREAVLPQSQPQAGDVKIALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEP4</accession>
    <name>A0AAD8XEP4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_741076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365049.1">
        <property type="nucleotide sequence ID" value="XM_060513080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEP4"/>
    <dbReference type="GeneID" id="85396978"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="59934" checksum="B795AAF5D654A7CC" modified="2024-05-29" version="1">MASSSPVASGFSWLGNENSPDSTIQPYGYIATAFLVVVFSILLKVSRHDDVPLLQPPPKWFRPTFLAQIEFFKTGKDLIAKGRATLRDKPYRVLSESGEILVLPTRFANVIRNEEGLSFGAVVMRDLHGEIPGFQPFGSVDDDKKILQVVARKQLTKSLNIITEPLSLETAFAANLIFGESQEWHQLPLKDTILDLVARLSSRVFLGPELCRNEDWLRITKDYTVLSFTAAVKLRAVPLRLRPLLHWFSADCRRTRDSLAEAQKLIAPVIEKRRAEKRVAAAAAATEGQGAAAPVSNDAIEWAEAEAQGGAYDAAIFQLTLSFVAIHTTTDLLAQTLIYLAKEPELIEPLRAEIVEVLKAEGWKKSALYNMKLLDSAIKETQRMKPVSMLLMRRLATKDVTLPDSNITIRRGDTVSVDTYSSIDPTVYENPETYGIHRFRRMREQPGGANKAQLVTTSPEHLGFGHGLHACPGRFFASNEVKVALCHLLLKYDWKLAPGSPSEPVVTGASMNVNPKAVVMVKRRLEEFDIDNLGFGDLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XES2</accession>
    <name>A0AAD8XES2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_26907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361000.1">
        <property type="nucleotide sequence ID" value="XM_060502042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XES2"/>
    <dbReference type="GeneID" id="85385941"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32348" checksum="D99DCFA7847CA183" modified="2024-05-29" version="1">MRSAAGAFDPTPHMGARIPSFPLFSSCSPSKIYPTAYAHRTRKVTRILQPQLRKSTSGGVTATVTATGAALLLHKIRRKRNPRAPFPSFLVAPGPRPHPAAKVVLSFRTIYGRLLSRDPVLVRAPNSPSPGAQRLAWHLDNSRFRISSFPPRRTPLRGSWTLAARVRPTLKVKLIWSKLEISRRVAMDTGSSAGVGAGLSAAGGVGGANLPIKRACDACRARKVRCLILHWPMSSCHSTPSIGRRADYVLVRFAVIEKNHVLTASTPASSVRIHRGSSPKRREPASSSPLNMRRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEU8</accession>
    <name>A0AAD8XEU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364702.1">
        <property type="nucleotide sequence ID" value="XM_060514197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEU8"/>
    <dbReference type="GeneID" id="85398095"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041974954" description="Cell surface protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="29335" checksum="BF2184C108DB11F1" modified="2024-05-29" version="1">MKYGSALLLAAFAATNVFAHGVIDGVQGANGVNLPGLSLIDDTPRDCASPRCGSEADTSIIRDRELGTAKASALGRTQGGGPVDAAAMMQTFMNGAAGNTTATKAAREIHEANLARRYANIAARQAGKGTKTPKGTVETGVKAATGMAAQQGMPTTADDGTISMTFHQVNQDGAGPLKADIDGTSGGTDPAAFKTAEVTQNVPGIGIGGLSGASTMDFPVKVQMPAGMTCDANVGGASNVCVARLRNAALAGPFGGSVAFTQSTAARKRAVEFNLKKRSERRSARDFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEV7</accession>
    <name>A0AAD8XEV7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_577229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365259.1">
        <property type="nucleotide sequence ID" value="XM_060504998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEV7"/>
    <dbReference type="GeneID" id="85388897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07821">
        <property type="entry name" value="PYR_PYL_RCAR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="155" mass="16711" checksum="82584DD1D901F375" modified="2024-05-29" version="1">MSVEGLDGRTVLASVTETINAPANEIWPFLSAIGAERIQIPGCTRSAVLEGYGLGAVRRVYFGEVYFDERVLVCDHTAFKLQYEVLEPSSSPATGVLAAVQLHSSGPEKTIVTWTSGARRVEQQHEDSVKLQAVGFCQGQIASLRKLTQTAKASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF33</accession>
    <name>A0AAD8XF33_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_699526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364942.1">
        <property type="nucleotide sequence ID" value="XM_060511414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF33"/>
    <dbReference type="GeneID" id="85395312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="77"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="37737" checksum="221C7CCA180DD67D" modified="2024-05-29" version="1">MPEAYHAHPDYGYPRDFKGYGEKGLACPWPNDAKIAVSFVINYEEGGERSVLAGDGVSETNLRENPMGPAKYNERNYSVESEYEYGSRAGFWRLFRLFNSRKMKFTLYAVAQAVEEQPEVATRCVEEGHDVASHAYRWIDYHDVPIETEKEYIRKCITSLKSLTGYAPKGWYYGRNSPHSRTLVPQVYEEMGEDLVWASDTYADDVPYWIDLPTERDKADPKGCLMVPYSYDCNDFKFHVTGSGFRDPQGFYTHLKNAFDVLYEEGQEGMPKMMTIGLHCRIVGRPGRLAALRDFVDYIAKKEGVWVATRTEIAEAFKAKYPYKKGQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF42</accession>
    <name>A0AAD8XF42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_619666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365529.1">
        <property type="nucleotide sequence ID" value="XM_060508140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF42"/>
    <dbReference type="GeneID" id="85392039"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="158"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif I" evidence="4">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="4">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="28129" checksum="8C6D12A6B911B196" modified="2024-05-29" version="1">MAAAVDTSNTELSKQYDTPMGLAHSTMQALKDRIKLHYDLASDYYLSLWGEHIHHGYWEDGSETKEQAQVKLIQLLLQLSGVGENSNVLDVGCGIGGTSRYLASTLGCSVTGITISTKQVEIANRLTKAEAEKQASSESSDKAKEIEADADGFVSLGRGRIRFIELDAEKMGDFFAGQSASFDAVWISEALSHFPNKALFFENAFKVLKPGGKLALADWFKAENVTETEFANDLKPIEGMLGSTCDLLGRCGKKEIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFC8</accession>
    <name>A0AAD8XFC8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_620141</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365287.1">
        <property type="nucleotide sequence ID" value="XM_060508177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFC8"/>
    <dbReference type="GeneID" id="85392076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106006">
        <property type="term" value="F:cytoskeletal protein-membrane anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07651">
        <property type="entry name" value="F-BAR_PombeCdc15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000045">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000164">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="949"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="294"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="677"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="735"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="893"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="774"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="849"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109307" checksum="A458CD4E35A92F63" modified="2024-05-29" version="1">MPISTADGPSVALSFANNFWGKEDAGVGPLLDRMLAAKQTCDELKAFYSARASIEDEYSRKLLSLCRKSLGSHESGSLKISLDTVRGEVESMAKQHQNIAAQMKTELEEPLAAFAGGMKERRKIVQNGIEKILKTKIQQTQHVNKTRDRFEQECLKIKGYLAQGHMVMGQEERKNKAKLEKTQISVATSNTEYENAVKALEDTTVRWNREWKAAADKFQDLEEERLDFTKSSLWTFANISSTVCVSDDASCEKIRLSLETMDVETDIISFIKEQGTGQEIPDAPKYINFCRGDVNDTQSETSDDDSYSVAQFPRSINPAFRSSSPQPSTYESHHDPNSSLAQDLGHKDPPLATPRAVVAPDSRRQDASPSTSRHLAHDTAPKDVSSSPRGFGLNPGHKDASPTARNYLQDTGRREILPPNAREAPVATQRPLDQIRQAAPVAHPPAQQQQQASRPSLDMSQRGSFAPVPHDPYPLDGMTMLCRTGPPSERSSHPPSARPSSRDSLSDYSNPTSLSSQEPVSGKVSPVKQEPVSVAPVPDKQVLKKRSGFFQNHSPFRRKSTKESPGPPANRNTWHPVTSQGSPARRPQLQTQETSDLLGDRSTVSPEPIDANASLALNVGQNVFSVTNPDLEKRKGSNVPAAQPETDPIALALAELKGVGVGVGKQSSVRVSADRYHGIATPTPGSQPFSRSVPAVGSSNATAGGLRGTPPPYDQQVVQRLGVPPQAVTAKAMKETSAKFTDQTRSMFNPANRPGSSYGGTTSSRPMTRGSDVPRAASPAPLRSASPRTAPMEDMRSGYRSAPRTASPRAGPAEDTRGGYRSSSPNPQGSLGRGSSRMSNVPRRGSEQPYYQQKSPSTVSRAASPAPYLEKMRPGSSHVANELAVQLAPVGDESYGSVRGRGGSRPGTSSSNRAMGLYEGGGPPGQGESRQRSKSVADPSRQYTRDGRPILHFARALYVYQAAIPEELGFSKGDLLAVLRHQDDGWWEAEIHGSNGRMGLVPSNYLQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGH5</accession>
    <name>A0AAD8XGH5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_718060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367149.1">
        <property type="nucleotide sequence ID" value="XM_060512019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGH5"/>
    <dbReference type="GeneID" id="85395917"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF167">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="32"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="368" mass="39913" checksum="4CA00598999971F3" modified="2024-05-29" version="1">MEFVSNPQENEGPTVLAATIAVTSVALIVVAARLWVRLGMIHSFGFDDGFMTSAMVIAIAGQGVLIMQVLHGVGRHVGDIDFTKDYPIAMQMAFVSQPLFLAAICLVKLAVGSSLHRIASKKLYKNLITGVMVSMTAYTIACVFTIIFQCTDVRAFWDFNVKATCWDVDTIKGLSYANSSMNILTDLLFGIAIPAPMLWGLNVPQRVRISLMMVLGLGVFACAAACAKVYYIVTSYGKAFDPTWDSRDIQMWTVIEANVGIIAGSLPTLRPLFKDFLGSIYGKGSKAPTAEAYYGRSTMRSGSNWQTLSNTQWPAYATRPMGTTTVATGTGGEDSDMSEDKIELRDSLTDGRGIKKTTVTTVMYSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGT6</accession>
    <name>A0AAD8XGT6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_410570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362890.1">
        <property type="nucleotide sequence ID" value="XM_060502911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGT6"/>
    <dbReference type="GeneID" id="85386810"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF9">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="3">
        <location>
            <begin position="41"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="135"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="616" mass="67398" checksum="C42215F9EEC78D71" modified="2024-05-29" version="1">MDEYHIKHTPWYQASVEAFSAKAAKKDMTGALDPNTTSNPDMIVAARLRPILEDEVAAGLIRGVFPRTSGNGAVDIHQIRKHIKPLGPPTLTTTSVQLDKAYGPDDTSEQIYQDLVEPLVPWAWSGGVSTVFAYGQTGSGKTFTVSEIEKLVAKSLMSGAMEGERKVYACIIELAGNSSFDLLNSRKPISVLEDSFGITQLAGALEIEITEAATLLELIEKAATFRRTASTFKNDASSRSHAICRIRIESPIPTAEDGLLYLIDLAGSEAARDIANHTPDRMKEAREINTSLSVLKDCIRGRATVDVASLTGKTKSPTYIPFRQSSLTKILKHVFDPAGRRSCKTMVLACVNPSLPDAGAGKNTLKYAEMLRVLLPKAKAQSYDPETPATWDNKRIKTWINSNSGSPAISGELVAPTETGSLLLRLPTPEFLTRCLKTPGVDEDQARAFHAKFWRLHIDSQKSGGKKTEVKSEAEPAEEKGRKTAMNQEMLSSSVDPNPKANDAPFKERIRPGMAVRWTPPSTFRMGLPGLNMVVILCPQLAVGPTVRDLSGDLVNQSGFTSTRGSKYLCAMVLPGFMADSYELSMWRQVVVDVDQMEAEVLLEYDSGTRYYHITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH10</accession>
    <name>A0AAD8XH10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_614397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366982.1">
        <property type="nucleotide sequence ID" value="XM_060507831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH10"/>
    <dbReference type="GeneID" id="85391730"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="63" mass="6588" checksum="41EA74AF62990D96" modified="2024-05-29" version="1">MSTITQAVPGCCYCCVPACGMHTCVFVGMLNRGTPLACPNSTSPTHSKSETRKRQPNGKTGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH34</accession>
    <name>A0AAD8XH34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_581523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363175.1">
        <property type="nucleotide sequence ID" value="XM_060505467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH34"/>
    <dbReference type="GeneID" id="85389366"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8239" checksum="9E8602EAA9C30D4D" modified="2024-05-29" version="1" fragment="single">DWYPDVPLVIQANQLIIGRLGLGHTLPELVAESARNEAGCHPGTMAAYFHHAITLELACLMSNDTVQMAIVKGVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH69</accession>
    <name>A0AAD8XH69_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_581320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363280.1">
        <property type="nucleotide sequence ID" value="XM_060505445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH69"/>
    <dbReference type="GeneID" id="85389344"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000039">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.13, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209:SF874">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10209">
        <property type="entry name" value="OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="5">
        <location>
            <begin position="218"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="373" mass="41720" checksum="FD2BE89D205FF287" modified="2024-05-29" version="1">MDLPIIDLDVFLNEPRDSAAVRDECEKAATALITYGALVLHDSRVAESDNTTFLDLLEDYFAQPTEELKKDERPELSYQIGVTLEDTEKPKCAVDEPCLKVIQRLAETERPLDITAHDPDPKCRFFWRMAENPPYETEFPGLNAPNVVPEAPHIRERWPPAMDRWGTSMKQAVTGLAEMAAVGLGLPADAFSSAGKYGPHLLAPTASDLVKYGKQDTILAGFHTDLNFLTIHGRSRYPGLHIWARNTGKKIAVKIPEGNYLLVQAGKQLEHLTGGLIKAGFHEVVVNEKTLAVIERRKAELPDRPLVRISSTFFWHLSSDHDLTPIPQLSEQAQKVRAEQFNLGRDEGEEVTYAPMKVGQQVQEELKHIALMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI97</accession>
    <name>A0AAD8XI97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_718939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365828.1">
        <property type="nucleotide sequence ID" value="XM_060512129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI97"/>
    <dbReference type="GeneID" id="85396027"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="407" mass="43695" checksum="FE4A2A738FCDE1E8" modified="2024-05-29" version="1">MGGFIPAREAKVCPIGSYHYTCSGFEGCCEVNPCETTRCPDEYNPYLTATELQALKTIASVAAPVLVSPTSSSSKASSATTDKKVQSSTSSDNPTTTLSSPEPTATGGIWLTDNRGSPASTIAPDDSTGTPFFVSPHTYTPTVPVETQAIDTSAPALAVKSDQHDLPVAAQAGIAVSALVVICMVIAAYFLCTKQRKKLRASRESISSMSKDGRKHSSEDETSQPAMTTNPFCPEEVFSPYGRRYEEPQTRFNRINDMSASRMMNHPVSPDTRDSIAATASPDFLSRTATTTPDVGYRTANSTPDFTFRMTTPDHMSRLGTATPELHGPPQQAAIAELASPGLPKVVEIHSSRSGLQKYKPYRPDGGSLYPVAETTPSYLTGTLNATQHERSEGRYVTSWSKWDPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJV6</accession>
    <name>A0AAD8XJV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_571753</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367930.1">
        <property type="nucleotide sequence ID" value="XM_060504436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJV6"/>
    <dbReference type="GeneID" id="85388335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF123">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="307" mass="33565" checksum="C525992DA47A0191" modified="2024-05-29" version="1">MAIAEQGMVMIVVGAILMFLNTFFVGLRLYTRIFITKHVRPNDYLLLTALAAFAALYALLVLGVQGGIGGSILQATLPGIASSLKVLFFLEIIYVVLTSAMKGSIALTFIRLSRSRILTSLFWVSIGLDVAISLAFIIYLLVQCQPIDFAWRLLDANAKGHCLPLTGQLYMGYALSIVTATLDGLLMVSPWIMMRGRGLNSRLKMYIYGIFGLGILATIANIIRLVALVKLKGSSDQLLDAAPVFNWSAIEVSIGIIIAGLIELGPLAAKYNIKGFESYAGDDTVMLTKPITHESRVDDYEMETRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK43</accession>
    <name>A0AAD8XK43_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">DNA replication licensing factor mcm2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Minichromosome maintenance protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_103539</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368887.1">
        <property type="nucleotide sequence ID" value="XM_060501043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK43"/>
    <dbReference type="GeneID" id="85384943"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17753">
        <property type="entry name" value="MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="20">
        <location>
            <begin position="488"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="693"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="846"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="847"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00078186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1728832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="867" mass="96699" checksum="BE75A1996D891EB6" modified="2024-05-29" version="1">MSSPLRNNPSSANRGLATQSSRKRGRTNGDDGSSIGPASSPMPSSPPAPFMAHGGDDDEDIEDEAEIQDDLDELDEMAEDEVDLFREGFEVDYRARDDDGYEGIDIDDEGEYGDMDLAARRRLEATLNRRDREVARRQRVPAAFLPGEDDEGDIDLSAQPRRRRHRYDEDPDEDMDADIMDEELSLEALQDVKAASLTEWVSQPFVQRTIKREFKAFLTEYTDDHGSSVYGNRIRTLGEINAESLEVSYEELSTSKAILAYFLANAPSEMLKLFDEVAMDVVLLHYPDYERIHSEIHVRIFDLPVHYTLRQLRQSHLNCLVRVSGVVTKRTGVFPQLKYVKFDCTKCGVTLGPFQQEANTEVKVSYCQACQSRGPFTLNSEKTVYRNYQKLTLQESPGTVPAGRLPRHRDVILLWDLIDKAKPGEEIEVTGVYRNNYDAQLNNRNGFPVFATILEANNVVKSHDQLAGFRMTEEDENEIRKLSREPGIIEKIINSMAPSIYGHNDIKTAVALSLFGGVAKVGRGSHQVRGDINVLLLGDPGTAKSQVLKYVEKTAHRAVFATGQGASAVGLTASVRRDPLTSEWTLEGGALVLADKGTCLIDEFDKMNDQDRTSIHEAMEQQTISISKAGIVTTLQARCGIIAAANPIGGRYNSTIPFSANVELTEPILSRFDILCVVRDTVEPEEDERLARFIVGSHSRSHPSTSQPGEDSMEVEHESENQETQAESPKKEGEIPQELLRKYILYARDRVSPKLYNMDEDKVARLFADMRRESLATGAYPITVRHLEAIIRISEAFAKMRLSEYCKAEDIDRAIAVTVESFVGSQKVSCKKALARAFAKYTLNKPGSQRRAGAGSQASRRAGAVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKM5</accession>
    <name>A0AAD8XKM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_606809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369173.1">
        <property type="nucleotide sequence ID" value="XM_060507397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKM5"/>
    <dbReference type="GeneID" id="85391296"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06154">
        <property type="entry name" value="YjgF_YER057c_UK114_like_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857">
        <property type="entry name" value="BLR7761 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43857:SF1">
        <property type="entry name" value="YJGH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="130" mass="14195" checksum="46AD0C68C5BB4CE8" modified="2024-05-29" version="1">MSRRNISSGSAFEAQIGYSRAVVSGDLIFVSGTTGYNYATGVISPNIVEQAEQTMENIAAALAEAGAEIKDVVRVRYILPDRNDFQKTWPVLQKYFGEVRPAATMIQAALMEDVMKIEIEVTAKKETASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLC6</accession>
    <name>A0AAD8XLC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369532.1">
        <property type="nucleotide sequence ID" value="XM_060507327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLC6"/>
    <dbReference type="GeneID" id="85391226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="89" mass="9378" checksum="343ADC10DCC45DC1" modified="2024-05-29" version="1">MYKHQVPSNRAIGTTLPVSGPQSGAPNLTFPNVGSGCGMGLPAEASSPSKPILPVDATPVSEVEFKPKSQTSTYQSSLLDTIRYEDQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLI5</accession>
    <name>A0AAD8XLI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_12270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369668.1">
        <property type="nucleotide sequence ID" value="XM_060501162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLI5"/>
    <dbReference type="GeneID" id="85385061"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="30996" checksum="3FF9709CEE9C592D" modified="2024-05-29" version="1">MARWWPPPPARHRSQPSWTASTCLPAAGACDRAHALCFSRSATHRWPPQSVKFVVGVRISLGSRSRPKSHDGRRPTSSDFALAALHNSRTDMHVYGIFSGSRAASQGAAWQSWESGARQIDQMQQNGNSFGELILRFDEGDWPTRFHHRLERGLKCIPLPLHFPSHCISPTPVRRLRHDQPLLPRGKENVRGISHQVSALLPAKADKEAGARCTHPLRGSPKLWRYRFTSEVNQGREYAGLWLTGSSLPLQHAALQSKCGFATAKICLESVAGRPAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLL7</accession>
    <name>A0AAD8XLL7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369609.1">
        <property type="nucleotide sequence ID" value="XM_060513593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLL7"/>
    <dbReference type="GeneID" id="85397491"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="27578" checksum="12EC9253E3286405" modified="2024-05-29" version="1">MAKTDLGARKEAVTLPPLRPPKPNLKSSFRKGPQYFASNMCWHQHGHNLGILLKHLSCNIKEEYHRFNMADTKSINGSEAAPAAGRVGAWTDAERFQLVLRVLATVLPDGKGVDWKNVNMEGRTLKALQGQWTAIIAQMREINTGENGEAAAPKQKTPRKTATKKKAAAAAEDGEEANGDQEGSEETKAVTPKKRAAATNADGTPKKRRTPAKKAAQSKAQAQAEEAQETEAEAKVEAESETQVVTKDEKDGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLU6</accession>
    <name>A0AAD8XLU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_727062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369748.1">
        <property type="nucleotide sequence ID" value="XM_060512771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLU6"/>
    <dbReference type="GeneID" id="85396669"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="622" mass="68152" checksum="FAE969B8070262E9" modified="2024-05-29" version="1">MDHFAEEEKFADLHDYKKKIVDRIPATVSDTYRSTLIKTIDYFIDTPDPGNCTLFWKVNAEYVSNVEPPSHFVIALCLASPSLALEGQALEFQKDFYAKNPDVAHHLNEWTVQGLINHHNKKVLSGDITGDYVHNIDGSPWNPEAIIVSHPNHKRPASAVEDMVPGPSSKRGHLAQEATTSLPFFENKDTPRLNFLAQAQEVPKDLRPILPPMPEVPRSPSIGDIMELPLPDRPISPNIFLNPIPGMKRDEERLDNGSLFNNPARFPDAPIPGMTEDNEHLGNVSLYGNPANFPTADFHNPFSPAREPSTFLANDDYGYGSYGMASAGYNSSGPAGFSNTQATPLPVDPSGGPYDNDNNPIAYGASEAPMTIYSSPSAANLPTGTLILAPPAVAQDSAIFANGDQASAVQDSTTQASAGAPVPPVNPWIAAEQASASRIARITTLIAQKQAEAQDKMKHAEALRTEHAALVNPFPLITDAARGAYFTSAEGDALRKFVMEAHDFEARAQKFYSEAVSAMFEASRLEKERYEESVDAGSKRVERMQTLVHKMAGFARDAQGLALGARPGEAPQLPGGVKDVGDIVSRMAQLKQSSEYLVQQIHVVEKDFRQYREYRQFMRQMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLZ8</accession>
    <name>A0AAD8XLZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-AMP-activated protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_567719</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369923.1">
        <property type="nucleotide sequence ID" value="XM_060503978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLZ8"/>
    <dbReference type="GeneID" id="85387877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000562">
        <property type="entry name" value="Snf1 kinase complex beta-subunit Gal83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="344"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="307"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="49034" checksum="3A910D79BFB6CB7C" modified="2024-05-29" version="1">MGNNPSSSSKPATPVSSQDSPKHHHHKRESKHIIPPRSAERVAAPPEPSLTQAQGSTATKGPRPLQAIPISNFTTGSPSSNSSNSAPPPKPPESKNVVRDAPSKPVDVPAAAAATESSSLRSHYSAHMVEPPLVGNSSVNDMSYLTRPPRMPLPIEEEIHTPGSPIIAPTDANDAGVAEVETLEDGMTRKSSALSTNTVEEEDGEELIVDKTRPTVPTRLEWRKGGGKVYVTGTIFQWNRKHRLHPVDGQPGVFAATIHILPGTHHVRFLVDGIMQTSPDLPTTVDFGNNLVNFIEVSADDIPATAPVEPGKDGVATAATIDKGGPKTSASQTDEQPKAPRGKEVPSPSQYFHQIPKYLVDFDQPEDSPAYQYAVTAIEKLPTPPSLPGFLGKPILNAAVLMKDDNSVLNMPNHTVLNHLATSSIKNNILAVSATTRYKNKVRHLLRYSTWSRLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM44</accession>
    <name>A0AAD8XM44_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_604266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370020.1">
        <property type="nucleotide sequence ID" value="XM_060507262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM44"/>
    <dbReference type="GeneID" id="85391161"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135518" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="12540" checksum="1EAD430C03C7B808" modified="2024-05-29" version="1">MPGSGLLLGGLRSAYCWARGILVGVCARAVSCMHVRTRRKCRLAGKLVGGLGCVAEEAEEEGMRWNCWGRNVPDTMTGVRNGRSRRGDGGMYGDPSSWVGMTMIPPSHSLYGVPILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XML9</accession>
    <name>A0AAD8XML9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_422904</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370147.1">
        <property type="nucleotide sequence ID" value="XM_060502989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XML9"/>
    <dbReference type="GeneID" id="85386888"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="24245" checksum="FFE871B26861BFE1" modified="2024-05-29" version="1">MPAGGLSLAFVLRSTIQDSSPAASTLRRARLELTDPYSPNDIYNVRLRVAATKARIKRASWTSTGHDGRYSIVTVLAHRISRLQGQFPDNAQPRAPEDVENLLSKVPSELQKEPPGPSFPSPAGPVWGNIAVPARADGRGLAVISCLFGCRGARIQAILSAPDNGGGDFVRVPCRRAKQNAPTKLHAANDYHDHGEDAGVICSCSARLLSFGPSVGRIFRGPTNFGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN13</accession>
    <name>A0AAD8XN13_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Trimethyllysine dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Epsilon-trimethyllysine 2-oxoglutarate dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">TML hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">TML-alpha-ketoglutarate dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_404704</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:14181"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58100"/>
            <dbReference type="ChEBI" id="CHEBI:141499"/>
            <dbReference type="EC" id="1.14.11.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.8" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370478.1">
        <property type="nucleotide sequence ID" value="XM_060502864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN13"/>
    <dbReference type="GeneID" id="85386763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050353">
        <property type="term" value="F:trimethyllysine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2020.30:FF:000002">
        <property type="entry name" value="Putative gamma-butyrobetaine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000001">
        <property type="entry name" value="Trimethyllysine dioxygenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012776">
        <property type="entry name" value="Trimethyllysine_dOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02410">
        <property type="entry name" value="carnitine_TMLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="8 19" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="18">
        <location>
            <begin position="70"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="17">
        <location>
            <begin position="166"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00071191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1730423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="50767" checksum="1ECDAD5A1536AF8E" modified="2024-05-29" version="1">MLPWRTIAPRAARRSASAFGAPAPPRLITYGGTFGSASRHLSATAAARHLDAKVVTDGVQFDGLTGVPTRRSTLPHFWLRDNCRCSKCVNQDTTQRNFDTYAISQDIRPSEIKSEEKGIKVTWEQDGHESFYPWHFIKHYLQNDHRSPEQVNYNFWGSDVGERRPVVEYDHLMSDKDDSGVAKLTNLIREYGFAFVDGTPYDTPAPTQRVLERIAFIRETHYGGFYDFVPDLAMADTAYTNIALPAHTDTTYFTDPAGLQAFHMLSHEAPPGQQLPQDGKLGGESLLVDAFYAAQILHKEDPAAYEILSKVRLPWHASGNEGITISPDKRYPVLEVDPQTRILQRVRWNNDDRGVVPFTDDVSPTEWYAAARKWDAILRRSDVEFWWQLKPGQVLIFDNWRVMHGRSAFEGRRRIAGAYINRDDFVSRWRNTNFPHEQVLNQVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNI9</accession>
    <name>A0AAD8XNI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ELMO/CED-12 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_330910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370733.1">
        <property type="nucleotide sequence ID" value="XM_060502414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNI9"/>
    <dbReference type="GeneID" id="85386313"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017124">
        <property type="term" value="F:SH3 domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="2" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0729">SH3-binding</keyword>
    <feature type="domain" description="ELMO" evidence="5">
        <location>
            <begin position="255"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="715" mass="80670" checksum="C5B654D05618EF0F" modified="2024-05-29" version="1">MDQADIPALLSRLASDEDAARKMAVFKLQSSINDPAFADVFISSGGLVILRRLIMSAGGNTLAYSLQSLTRLLEVDMGWEIFEGSSSGDLVERIVELIVTNPLVNILRGAMSILVALVGHTQSSRPTTPRTPGSFGFRALKPAVAVYPQFFELVIAQLQSADHALCANALMLINAMIRDAVSGDTNITKANNPAMEEWSKFIKRLQDLGLIKAVYNLMQSSSLQDLAHPLLEFQSLTKVLLRKWREVRVDLERPEHRRGLKGLHLASNPEKQVNGIHRLDEINELGKKGSRRHNPEKWRRLGFETESPTQEFEVPGFLGMMDLTDYVRKNEDSFQKMLLEQSTKPRNERCPVARASLAVTMILYDHFEVEKSDVEDIKGYQGLDGIKNNEKLFRPLLLQWSRLHTAGLQAFFRVWKSTAAEHLDFEKVAELVRILIEQVVGQASRTKDVLEVEEELLEYDCTRLRELQMELLELSFEDQWGQHLYQVREELRQEALQFVKEQRIRCLLQGSWFSKPLPRRDTNPRDENLKRRLYTPRPWRFAKLSHNRRYLHYADFEAQTAQDPGLDILTEKVDLSTISSVVSNVSASNEESRSATSSSTLKNNVTVKSTTKITIFSYANPAEAAGGGDAKEQAILTLNPVTHSLASEWLDGLLMLLNQAPITAETNKLVNLVSDFGLKIRLLNVRIEAAYTGPPPGAGVIPSRDGLDEDYFYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNN9</accession>
    <name>A0AAD8XNN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_646710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370872.1">
        <property type="nucleotide sequence ID" value="XM_060509999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNN9"/>
    <dbReference type="GeneID" id="85393898"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="31613" checksum="C96384DA04F7D0B8" modified="2024-05-29" version="1">MSANEEDFTPFDPVRCEHYARFASHLDRWQFDVMYWLLFVFNLFILFLAAWNYTRTLDAVSELPETDAKRKKAIKNCIWFNLGCVCVSLATVIMEVFTLMALQFCDGEDLMSLYWSTFTMIQVGSLIAVCGVILALVHQLRQRKNPPWALALGTPVLVIAGLFHYFHTCMVRRVKKASARKRKMSDAGTLPMSQVNTIQAESSDEDDGIQGAEIIGLTMDGGPIIHFKDAVPYNLPNNSEIIGRCSNDKPIVICRRDGFQLIYNGTDERAPSPNPATKSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNR8</accession>
    <name>A0AAD8XNR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_747093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370825.1">
        <property type="nucleotide sequence ID" value="XM_060513375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNR8"/>
    <dbReference type="GeneID" id="85397273"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38849:SF1">
        <property type="entry name" value="SMALL SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060379" description="Small secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="18753" checksum="19B2CA54D409F0E6" modified="2024-05-29" version="1">MYFSKIAVLFTLAATGLSAPIEGTEKRQAKLLSVQDYSQFQVSDGTGGNALAEVAQKFPVAQIKADLAGVSKDDLAILQAARVAAEGAETDAGGFNDAIAKASGADADALKVGKIKNKVLKLQLEVLALQVQQAQGASNQAKIDAEQKKLDNNVKTDTASKGKTSQSVSFSATSAPKGKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNY5</accession>
    <name>A0AAD8XNY5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_342543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370904.1">
        <property type="nucleotide sequence ID" value="XM_060502467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNY5"/>
    <dbReference type="GeneID" id="85386366"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000201">
        <property type="entry name" value="C2H2 finger domain protein (Gli3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000031">
        <property type="entry name" value="GLI family zinc finger 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="340"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="42174" checksum="AD3737EF52090D60" modified="2024-05-29" version="1">MARGDSTPPDSPLTSDNNNTSEEEEVHDYEDESLLRPSKRQKLGAASTTSPAVVAEPEPEAVPEPDPLEGMSDVSSDTSGDIPSSPINAKLDEEDFQEQVTSCAWEGCDAGDFGNMDKLVEHIHSDHIESRQKKYTCEWTGCSRKSMGHASGYALKAHMRSHTREKPFYCYLPECDRSFTRSDALAKHMRTVHETEALRPSDPVPKSMQAGPTGKGKLKIIIKTPQSHAAGHDDAIDDGADDDELSADLFTPLTEDQGFTREELKIPLERLYKLCRFQVKWAQEESVKLAEEVKYWEKQYKDLWREKEVLFSQVVKSEVDWHERRQAVLSGAADVQLSGVLESQEGNQTAANGEGADSQETSKAEETLVNGAKSTEVAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNZ8</accession>
    <name>A0AAD8XNZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_600932</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370916.1">
        <property type="nucleotide sequence ID" value="XM_060507065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNZ8"/>
    <dbReference type="GeneID" id="85390964"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000698">
        <property type="entry name" value="Putative pre-mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="4">
        <location>
            <begin position="65"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="291"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="375"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="482"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="57213" checksum="DB8FBBA1D7A990AC" modified="2024-05-29" version="1">MMHPSRQAYVEEAMDEDRGIALEDVPVDHDYEIPSAFAGAAPEKTSAVLAQMERKKLAASIAVPTDDNRVRTRLREMGEPVTLFGEGKPERRDRLRNLLVTQLLANQQEMDGIENGDITMEDAEDEDEDEQDEEFYTPGGQALLQARIDIAKYSLPRARRRVQFQKAESTIPLRTHVKFRKQIKEKLDGFELQGSQTAGERHVSMTRLSPNGELVAVGNWGGALKLIEIPSMEAKMNLRGHTQKISGISWYPGSTLPEANVSPDTVNLASGGAEGLVHLWSLNKDTPLSTLTGHGGRVSRVEFHPSGRYLASASDDTTWRLWDVETTAELLLQEGHSRGVYAVSFNADGSLLASAGLDSIGRIWDLRSGRTVMILDEHIQPIYALDWGSDGHRVLSGSADGWVKCWDVRKVQRTANLGAHAKAVSDLRWFRGLDDPIDGYPPGADEKGAQQPKKAGTFFVSGGFDAKIKVFSADNWGLVQTLSGHSGPVASVDVSRDGKWIVSGGHDRTVKLWGRNDGEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPA5</accession>
    <name>A0AAD8XPA5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_746806</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="function">
        <text evidence="9">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370989.1">
        <property type="nucleotide sequence ID" value="XM_060513322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPA5"/>
    <dbReference type="GeneID" id="85397220"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1220:FF:000002">
        <property type="entry name" value="RNA polymerase II transcription factor B subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="71" mass="8132" checksum="291B4CA9D54E73C7" modified="2024-05-29" version="1">MPRAIRGVLIECDPSIKSIIVNIDSNNHDYIIEDLDDQHVVVKENMVGLLKRQLDERLKETQQPDESSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQP7</accession>
    <name>A0AAD8XQP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_564257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371815.1">
        <property type="nucleotide sequence ID" value="XM_060503619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQP7"/>
    <dbReference type="GeneID" id="85387518"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="534"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="750"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="761" mass="83673" checksum="291B3B994EDD86C5" modified="2024-05-29" version="1">MAQPQPSPATPGALAQSLFGGPAAQALSTPNQPSNTSTQPSPSPMDQTPGSAASSNNTYIMPNSPIKSRGTLDGYRPRVTRTLGQRPACLVNASVTYCGNNHIYAFGGFDQYTDEVYNHVLKLDLVSHQWSLVDNYGDIPGVRMGHTATLYQGDKLLVFGGENEHRTYLSDLIIFDLKTAHWTQPSVTGPVPKGRARHAAVLHEDKLFIVGGITGHDNYVLDDICYLDLKTFTWSRSWRFVGRFDHSAYIYGDRVWVFGGLSEDMDKIGDLWWLDLKGSPAFDSAPHVGIYDRQSGTSRAVGSPRQPYSMAHPPPAVGSSGYAANSRTQQVNPPSFQLKTFSPMAPGTISSLKFISGPNIPSQGSGIHFHVYSSGTLLDFVTPAATITSKECSLSALDLGTLRWQKLAEGREIFKSGYRWHYCTMNEDGTKAWLLGCPTDPVASDLGPNGFEEYLSDIMEIDLRRYGFLGNNFSSEPRIESRPTTRVVDQPSKGLGADLAKLFDHPPESGSGTDFIVTALEGDYEDDDMMSRVTDASAGQNWLAPDAPTSQPIHVHKLILQARWPHFARLYNSQMAEFHTKKMHIPEPYSVVKAFLYYLYTDSIHGTSVNESGATTDLSDVAGLLVMSNIYGIPHLRLLCVNRLSKELDVDHACVIWHCAGLANEEWLRKRAAQFCLTHWGRIVRTQGFLRLPRSALVELSQEIDMEGRVVGGDELEYVGGLAGSRFGDGCSVVSRKESVSSNHTQLLDSEADDEDGMEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQT2</accession>
    <name>A0AAD8XQT2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_597178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371963.1">
        <property type="nucleotide sequence ID" value="XM_060506889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQT2"/>
    <dbReference type="GeneID" id="85390788"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.200:FF:000003">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="8">
        <location>
            <begin position="19"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="7">
        <location>
            <begin position="142"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="26185" checksum="548E8A903D6DC4F2" modified="2024-05-29" version="1">MMPRQPYAPTPHSYIPNTTLSATINLDEEVKLADTRAERDLQDSLAEIFSIIVTLDELEKAFLKDAIPEADYTEICERSLKQYKSILADETVAKAFGGLEEFKAEWDLEVPRATERIRVGMPSTTVTASSSAAPAPAAAGNTSGTLILEATQEFITFLDAVKLGLLSKDQLHPLLSDVIQSVNKVTDRDFDSRGKIVQWLITLNQMKATDELSEQQARELEMDIQQAYQGFKSTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZG3</accession>
    <name>A0AAD9CZG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_50911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369392.1">
        <property type="nucleotide sequence ID" value="XM_060503300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZG3"/>
    <dbReference type="GeneID" id="85387199"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="416" mass="46619" checksum="BF90509592F6AF51" modified="2024-05-29" version="1">MISSLSEMEDLRSPLDRLPLVIQHPSFFENPTQHLSSSRSSSAAGHHTCIDGTQLSQPDYRPKYVVNDRRARNGVDADDAVERKDSVMTDIADADESLETKTTSLSVSPHSLWSVYSSESGGGEERTEVMMTVRKLVREFDEEGESSTAPSEEEKKKAEEMEMEKRKKEREVWQKEMDKPQKKMNKKRKKRESATLLSGSPWGGDARWVNGGRGGRNNEGYEAPGIFLQPEAPRPLPPTPTGPVSVFPPEPKKRKEEKKAKKEKKEAEKDELLVLPKVPWCHQSGGCRQKRGRRRRKMAGFAARSVDLLRRLFGGESREKKDKKGKGRARCRICGDELGFAVERAKWQEDRDAAAAAAGDKESSSGACGRTLEADTDRKDMDRAEADITAVAECESRSTLAAVRLTKIPEAWWTTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1J3</accession>
    <name>A0AAD9D1J3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-C homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_566588</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370683.1">
        <property type="nucleotide sequence ID" value="XM_060503863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1J3"/>
    <dbReference type="GeneID" id="85387762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019237">
        <property type="term" value="F:centromeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051455">
        <property type="term" value="P:spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06993">
        <property type="entry name" value="cupin_CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000033">
        <property type="entry name" value="Centromere protein C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025974">
        <property type="entry name" value="Mif2/CENP-C_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028929">
        <property type="entry name" value="Mif2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11699">
        <property type="entry name" value="CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15624">
        <property type="entry name" value="Mif2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mif2 N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Mif2/CENP-C cupin" evidence="8">
        <location>
            <begin position="548"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="455"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00057947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00075033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF15624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="650" mass="71693" checksum="9A4BE55E105D8A23" modified="2024-05-29" version="1">MAPPRQSNVRRRETSTGDFHELGVKGRKTGIELPDTGVRDEHGMQPIDGLFSSPEKDNGSASDDGEQDMELESESGPGPSTIMKNHPRLVPRGTSPRKTNLGSPAMRHPSFGPSSSPTRLSPQRRSSSPIEPQPTRGAPVSRKLDYGALEKNGPGLNGKRPNGFKSGRAVSSEDEEDEEAVLQAQNGRVENGEEESMQMVSMDDGEVPEPESEPAASETEEISEAEIPKQPAKRKGRPAKAKPVVQEEVEEQSNHESEPEQAPVKRRGRPAKGKGKEKTQSDEPEPEAEEVSAPKRRRSRNSDGDKAEQEEEDDRASKRQRKEPKKATGGARGRPKALPQEEEGESSKQMAKAASKAKPGPKGRPGRKPQAAAGEDSILGVVQKGPPMPKARGLVSQKQKQDPHSITHTRSGRQSYRPLAFWKNEHVTYDEDEAFEDGKKGNRFLLPSVKEVVRVEEEEREAARKGKPRGRKPTAKAGRRRQQVESEDEEPAEPWEQDPGSVDGEIVVWQPEHEFNPPAINEQVEIDEERIAVAAGAIQTRDIRDATFRFAKTLSLPFFGSGVVDLPPGAEKRPKNSRKMQMVFFVFQGKVLVTVHESQFRISAGGMWFVPRGNYYSIHNDYENPARIFFAQGCEMSSGEAGFSQDTTIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1T3</accession>
    <name>A0AAD9D1T3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DSC E3 ubiquitin ligase complex subunit A</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Defective for SREBP cleavage protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">RING-type E3 ubiquitin transferase dscA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_604281</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic component of the DSC E3 ubiquitin ligase complex which is required for the srbA transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. Required for growth during hypoxia and triazole drug susceptibility, as well as for virulence in a murine model of invasive pulmonary aspergillosis (IPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the DSC E3 ubiquitin ligase complex composed of dscA, dscB, dscC and dscD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370026.1">
        <property type="nucleotide sequence ID" value="XM_060507265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1T3"/>
    <dbReference type="GeneID" id="85391164"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000626">
        <property type="entry name" value="Transmembrane ubiquitin ligase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="695"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="22">
        <location>
            <begin position="789"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="510"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="756"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00056116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00071072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00077885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00082128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1729971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="856" mass="95729" checksum="266282505945FAB7" modified="2024-05-29" version="1">MPSPYRDPRLVFLALAFVGVFWILLSPGNGGASLFSASDLAIQRLRRHQHALDLLNTSTYGDFSPRENGTSKDLLPRSLNLTGFRPEDGFAWDDLERFRERCLEWSHNAIPPVGGVNLWDIGEGEPVWQNATGAVKGTWIRREATSMREWTNYNLSAITPSLHWSGAQSEWARNITGDEGKILMDLVDTGKHGRELDYRSDIEGDEGLSSGGKVRSAKASITIEDVKGSGVNWEMRLHGVQWPRQGTILLTTTSEKFDGIFGLPHLAPSLDFFQSSQRLLNLTLAEVLRRKEKEVFNDGVMPWTSDLSNPPDTLNPTPHCEYIMYAQVHPPDRNFLDMKGFHPTREGMARIISDIEQELRFPEGAPIRGVPELQLSAVIWSPDCAFFLETKGPPDFAPVDGQHLQGMKTEIIYHKIRVWILLFAMVILTQALLLKQQMKESATPSTMGRISYSTISMMVMVDGGIFAAASMWALDASITYLESLSLLFSAFLSMSLGGFFLAEIHKVQEPENRRRAEREQQNADNDSPRTPATPAQDLEADSLPRPVTAGPRRRAPSPPIIIPSDQDIDAEIADATSGAAAVPTAGTGAGGGHRIRPEVTFQSVIFRFAMTVSLILLVSIASTSWYPRVRNFFVNSVALVYFSFWVPQIHRNIIRNCRRALTWQFVIGQSVLRLLPFAYFYVYENNFLFAETDRRAFLVFCAWLWIQLWVLAFQYVLGPRFGIPKSWTPDAWDYHPVLREDGVEAGGLPIGLLSEPGSPSLERVRSGSGGEDVKDKKSSGGSNLRAIDCAICREVLEVPVMRAGEEDPTAGGVVGVFTRRNYMVTPCRHIFHSACLEGWMRFRLQCPICREELPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U594</accession>
    <name>A0AAD8U594_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_736274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000252">
        <property type="protein sequence ID" value="KAK1705021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357523.1">
        <property type="nucleotide sequence ID" value="XM_060512991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U594"/>
    <dbReference type="GeneID" id="85396889"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="177"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="187"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="680" mass="75281" checksum="E092D3FD33A888A7" modified="2024-05-29" version="1">MYMLCRPPGLTLRLRLRSHIHNPVLKKKKEHFTPSPSLPQSFVSAILTSLSSPIQTGHASTGRKCEGYAVVVPSNRAIARARSRTTRLRDALAQARAGWEFESDQATVEYFARDVAPNLPQNFENKFWSDLVPRLRATIKTATTTAATTTTADGGRGNPQADEHYGKALRLMANKVAPERGFEDVQTTLGTTTTTRTTSTTTTIRNDSSRSFGSPSNRSSPSLSSAGPSSAIQSPAAMTPGISSIPELAEPDRQDTLTPTNPFTSPPSQAGGDDPDDDMTQPNDVDVVLSCCILFIATEFLRKSFDAAMQHLASGINILNNVDYDELEQDTLDEIVPKFHRLSIIQLCYYDKPGFPSLNLQHGGGISSSSGVGTLGGLGSRYNLGPFDKSSSIYLPKRAVDPILLDAIRYIRSADPGSQTDSRLASKGPVMSEEQKHICASLDRWHAAFLAFVENPRKDDDGDRPLPKHQGLICAETEMKYQAAKICISVCRSHDESVYDCFKENFARIVVLARLILDSCPDVPPEAPDDFQFDFKPSFLSLVEFVIVKCRWLDIRYQAWLIAWELAMGRREPVTLGEGHELHYIGKRMIEREHNVSIEEVTRQNASLFSLPAEEMRVKDYLTDARFADLVQTDDKKDKSSSAAAVQVPYTQRLLLRCGSCELDQLAGWMEGYEFSGREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8M7</accession>
    <name>A0AAD8U8M7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_596015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000353">
        <property type="protein sequence ID" value="KAK1701607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357019.1">
        <property type="nucleotide sequence ID" value="XM_060506843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8M7"/>
    <dbReference type="GeneID" id="85390742"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046281">
        <property type="term" value="P:cinnamic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033494">
        <property type="term" value="P:ferulate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049383">
        <property type="entry name" value="UbiD-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108:SF17">
        <property type="entry name" value="FERULIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20695">
        <property type="entry name" value="UbiD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-octaprenyl-4-hydroxybenzoate carboxy-lyase-like N-terminal" evidence="1">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="101" mass="11377" checksum="1DA979E11DFB37DF" modified="2024-05-29" version="1">MTDKPNSSAASFRTFIEELVKENDLLSIMKEVDPHLELAAITRKVYETRDKASLFQCVKGRTEQASFVFLGHQSERASSLASVSSASQSRWGYRLHRVGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Q5</accession>
    <name>A0AAD8U8Q5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine carboxypeptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_589727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359551.1">
        <property type="nucleotide sequence ID" value="XM_060506260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Q5"/>
    <dbReference type="GeneID" id="85390159"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1712935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="54929" checksum="DEA96CB66C987758" modified="2024-05-29" version="1">MPTPQLSQFPKMGGLQRRAHSGTQVHNGTFDQYLDHTDLSKGTFKQRYWYNSEHWGGPGYPVFMLNGGEGDAEGLTGYLENGTLTYLYAETYKGAIVLMEHRYYGKSLPFKTFTADTLQYLNVPQAIYDNTHFAETVELPFDKKKGANADKSPWVLIGGSYPGALSAWTSVIAPGTFAAYHASSAVVQAIDDFWQFFTPIEQALPRACSADVKLVIKQVDSVLDKGSAKEIDAMKEEFGLETLEDNADFAWYLLRPIIEWASNETAVYEFCDYIETSTNNGNVIKGTEKSGVGLKAAWKGYTSYMHSRYSEVCEGEEACDLYGKAVGYNRPNDLSADRSWTWQLCNEPFGWWHVGPPKSDGTNIVSSHVRPADRQRQCDLRFPQTFGFKPASSEGFTAAMFNDWTGGWNATFENVLFCDGEHDGWRSASMNSDYRPGGLVKTTEQTATFVVKGANHVPDFLLNNGEDNAAIIEQEVKVIGKWIKAWKPNKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9R7</accession>
    <name>A0AAD8U9R7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_680754</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat rae1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360132.1">
        <property type="nucleotide sequence ID" value="XM_060511206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9R7"/>
    <dbReference type="GeneID" id="85395105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000190">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="116"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1714989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="39229" checksum="E74EB155389E3407" modified="2024-05-29" version="1">MSGLFGAASSASSSNTVGDLKQDVALNNPPEDSISDLAFSPAQNQTSDFLAVSSWDKKVRIYEIAPNGQSEGRHAYEHDGPVLGCDWSKDGTKVLSGGADKAVKLCDLGSQQTIKIGEHDQPVKSVRFFESSGTPMAVSGSWDKTVKYWDMRSPTPAASLACQERVYTIDVRNDLLVIGTADRYINVVDLKNPTKFYKTLQSPLKWQTRVVSCFADAAGFAIGSIEGRCAIQYVEDKDATSNFSFKCHRDPPANNVTNVYAVNDISFHPVHGTFSTAGSDGTFHFWDKDAKHRLKGYPQVGGSITATTFNKTGSIFAYGISYDWAKGFQHNTQAYPNKVMLHPVQADECKPRPTMKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T6</accession>
    <name>A0AAD8U9T6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EC7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1710012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358708.1">
        <property type="nucleotide sequence ID" value="XM_060506461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T6"/>
    <dbReference type="GeneID" id="85390360"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042053625" evidence="1">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="85" mass="8941" checksum="0FB516E4B1A660BD" modified="2024-05-29" version="1">MVNMRISLILLPLAAAMPPSDFAPNSLVRRHCVEPKNCGATIQGTMCNFCCAKDVKPDSTHCKSANAACQAGGKPDGVTFNCDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Y3</accession>
    <name>A0AAD8U9Y3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_657792</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000217">
        <property type="protein sequence ID" value="KAK1707126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357974.1">
        <property type="nucleotide sequence ID" value="XM_060510987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Y3"/>
    <dbReference type="GeneID" id="85394886"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1707126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="526" mass="59361" checksum="73615FF1BB53EB26" modified="2024-05-29" version="1">MSIFVVPVETARPLVVLAAAALIVFPIIYFLCLTVYRLFLSPISHFPGPKLAAWTYWYEFWYDVVAEPEYTFKIGRLHKQYVRINPDEIHIADPDFYNTIYAGSGRKRDKWDWITRSFGVDESLIGTLGHDEHRIRRAALSPYFSKQSVRALQPLVDRNMGILLGRFREFAQSGAPLKLDDAYAALTNDIVEDYAFGKSEDRLQAADFDPSFRDAMLQGGKAGHVLKHFPSLMDMLRKLPDSLLLKLSPAMGAYSQLQTSVKKQVADITQAHQMHAYDKTRRTIFHEILNSKLSDYDKSTDRLWQEGEVVVAAGTITTAWALGVSTYFVLATPDILSRLKAELEAAIPDPSQPLSLLVLERLPFLTGVVQEGVRLSHAISHRLHRICPDETLVYRAGDREWRIPPGTPLSMTSNLVHHDERVFPDSHTFKPERWVNDPLLDRYLVSFGKGGRACLGINLAYAELYLTLAALFRVYGTEEVQGKDDVGTLKLFETTAADLVITSDTVVPVMPEDSKGLRVTVHQRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAB9</accession>
    <name>A0AAD8UAB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_657624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358169.1">
        <property type="nucleotide sequence ID" value="XM_060510974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAB9"/>
    <dbReference type="GeneID" id="85394873"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45575" checksum="E7382285B7B93016" modified="2024-05-29" version="1">MACYDQRRYGSQATIGAFFASLRLVDGLVDGETESRSQIVVNVRMPSITDIPCELVASILRSLDDFETLTSALLTCRHIYSSFKQIPGTELAILRGRIGLDLLPYSVASLDASRLEPSPGDESSFCGLLDLLYDDPSQLVARTASMPPELLRNLSRKHDWVTTLALNCRKAVGLSSSEYSRFCRAFYRVDLFYVLFGAVGNFNTGFGEGNLLLHRHPPWENEQLGCVHDFIKAKYQEASSDVFAYNAPFDEYQTDYFTTGGNNIMIQIWLSHGLDFLRRLMSTDSHESKRVLLVSAINAGWTHLPEALVCIMDSHAYNSTNLEDMSTSELTTIIPAYENICNTDKGPYAGWYAANTSVQPLFWVYRLENRWLRRRAYVFWDWVYVREPDVLKLFATTSDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAU3</accession>
    <name>A0AAD8UAU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_641817</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358409.1">
        <property type="nucleotide sequence ID" value="XM_060509576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAU3"/>
    <dbReference type="GeneID" id="85393475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000009">
        <property type="entry name" value="T-complex protein 1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000070">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1708891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="61493" checksum="DA21612CDFA9AB20" modified="2024-05-29" version="1">MASMFEQSGSGTLFLGGQKISGADIRDQNVLATQAIANVVKSSFGPSGLDKMMVDDIGDVTVTNDGATILSLLDVEHPAGKILVDLAQQQDKEVGDGTTSVVLIAAELLRRGNELMKNRIHPTTIITGYRLALREAVKYMNENISIKVENLGRESLVNIGKTSMSSKIIGADSDFFANMVVDAMLAVKSTNGRNETKYPVKAVNILKAHGKGSLESQLIKGYALNCTVASQAMPTRIQDAKIAVLDMNLQKERMKLGVQITVDDPQQLEQIRQRESGMILERVEMILKAGANVILTTKGIDDMVLKTFVEKGAMGVRRCKKEDLRRIAKATGATMLSTLSDLNGDEKFDPSYLGHAEEVVQERISDDECILVKGTKSHSSASIILRGPNDFTLDEMERSIHDSLNAVKRTLESGSIVPGGGSVETALHIYLEEFAGTVGSREQLAIGEFAQSLLVIPKTLAVNAAKDASELVAQLRSRHALSQRIQEGEANDDEKTVARKKAYKNYGLDLVRGKVIDEIKAGVLEPTISKIRQLKSAVEACISIMRIDTLIKLDPEQQAEDDGHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBT1</accession>
    <name>A0AAD8UBT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_124639</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358890.1">
        <property type="nucleotide sequence ID" value="XM_060501173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBT1"/>
    <dbReference type="GeneID" id="85385072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF188">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1710611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="58066" checksum="B8B0BFC32499CDB1" modified="2024-05-29" version="1">MQTYVLVVIIALFVGVQLLAKIYRGFAAPLASVPGPFFARFTDLWYAWRIHQGRFEVDNIELHRKYGPIVRYGPNRFSINDPHAAKVIYGHGHAFSKSTWYDTWGDPNPHQWSLFSDRDEKRHSENRRLYQNMYSMSSLVHYESYVDKCADLFSRRLSEMSGRGKTAEPVDMGHWFQCYAFDVVGMITYSKRLGFLDRGLDVGAVIKNLENHLYYATMVGVYSYLHSYLAPIRSRLGKQGTGRQFIVEFTKGCLADHQAKPKAVDAEDTSHLSEQSGTMDFLSKFLGKHSEDSSKFSQYHVLAGCVSNMVAGSDTTAISLSAILYQLLRNPKEMSKLQKEIDEFYSQRAGDPRRINFQESLKLPYLQAVIKEALRLHPATGLPLERVVPEGGATIAGKFFPAGTIVGINTWVEHHHPSIFGEDAASFRPDRWLTTDTDRLSAMNRHWMPFGLGSRTCIGRHISILEISKLMPRLLHEFDFEICRDATWVTRNCWFVKPVNFQVRVNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC97</accession>
    <name>A0AAD8UC97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="14">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_683184</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21 14">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358926.1">
        <property type="nucleotide sequence ID" value="XM_060511227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC97"/>
    <dbReference type="GeneID" id="85395126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1040"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1074"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1103"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1147"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="124"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="18">
        <location>
            <begin position="928"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="572"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="11">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
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        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>ATP</name>
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        <location>
            <position position="532"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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    <feature type="binding site" evidence="12">
        <location>
            <position position="682"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="762"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="12">
        <location>
            <position position="763"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="860"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="866"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="904"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="905"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        </location>
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            <name>Mg(2+)</name>
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        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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            <dbReference type="PIRSR" id="PIRSR606539-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1710866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1227" mass="137395" checksum="C12DF74CAFB201BE" modified="2024-05-29" version="1">MPSSPAGRRIPIRLGQKSPLHDERRGKPYISNSIKTSKYNVFDFLPRQLLYQFSRLANAYMLVISILQMIPGFSTTGKFTTLIPLVIFLGLIISKEGYYDWKRHRQDVAENNRQAMALRRSNPTGHQWMRVSWKDLKVGDIVSLSRDEDVPADMVLLHADGQEGVAYVDTMALDGETSLKSKQRPAKLPDCGTIEQIASSNAELLAEDPNADLYRFDSKLAVDGYTIPLTINEVIYRGSTIRNTTKVIGVIINTGEECKIRLNSNKETRPKQPALERITNFIVVFLMFYVLISSAATSMGYLAWKGSEEDHAWYLSGASVPFADIFVGFIIMFNNVIPLSLYVGLEATKLGQMTLISNDLEMYHDETDTPAGVNTTNNLDDLGQISYVFSDKTGTLTENIMKLRRLSIAGTSWLHQMDVPESSTASAHSTSNLTTEHMLEYIRSKPNSFFASKAMKYILAMSLCHTCLPERTDDGEIDFQASSPDELALVRGAQDLGFLVTRRSSQSITVQIPHADGNSSCTVFEILDVIEFSSKRKRMTIVLRCPDGRLWLICKGADSIILPRLRMAPADMKSTRNSNAEPLKGVTSMPSRWSSRRSRLPAETVTEIREDDDRSIYSQMSGDVDEFGIRLQPQRPQNNLARGRQNDQSRFGFLEGSWIADETRTLRECFAHIDDYATEGLRTLVYADKFLDPGEYNNWKHLHHEAETSLVNRQERIEEVSELLEQSLDLVGASAVEDKLQTGVPETIEKLRQARIKIWMLTGDKRETAINIAHSTRIVGPDTSLFVLDVEKGDLELQLTGVADEVQYGLPQVYSDPTRSHTAIVIDGETLTAIEDPSAIRLRHLFVTMMTKVDSVICCRASPAQKALLVTEIGKGPQKKSRWYSWLSPTTNKPLTLAIGDGANDLAMISAANVGVGISGREGQQAGRVADFSISQFRYLSRLVLVHGRWNYYRTTRFILATFWKETFFYLPQALFQEQTGATGTSLYEPGSLTFVSFFTAACILVIGTWEQDLHSRTLTVVPELFKYGQNAEGLNMSVYFSWFSNAMISGLIVYAGAWAGYTDSEMIDDDGLYAQGLLTFALCGVWVNIKLLVIELHYKTRVALWSIVGSMAVLWAYLLIAGAISSPSAGPYSVRGGLISQFGRDPAWWSTLVMVLCALLLMEMATKALRQSHVLRAWLSRCWSSSERVDGKGGGVREGFNDWEPRLWQEMERDASVKRILHGLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCB9</accession>
    <name>A0AAD8UCB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360223.1">
        <property type="nucleotide sequence ID" value="XM_060509219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCB9"/>
    <dbReference type="GeneID" id="85393118"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="60" mass="6796" checksum="ABAE40BD93B2BE9E" modified="2024-05-29" version="1">MPAKRIVVQRDSQRSRQPKGYFRSTYDALTSSENAPIVRSVAIFGVSHHARPSHRSIELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCT3</accession>
    <name>A0AAD8UCT3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359414.1">
        <property type="nucleotide sequence ID" value="XM_060510883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCT3"/>
    <dbReference type="GeneID" id="85394782"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="16104" checksum="90528AA4CD056372" modified="2024-05-29" version="1">MYDVGLVLFVTLVTLVNFLGGFLAQLRGRPVADLMLLMNLANKRLSGCSYQQAYPSLNVRGRNSIFKLGWEAFTDGRSDLSRAKWVRMCVLDLGRGSSADRDVEIGPSVREPQTQDVQTLEADVKRSRLYEHRVEAKRRAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDV0</accession>
    <name>A0AAD8UDV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositolphosphorylceramide synthase subunit Kei1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_92297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359584.1">
        <property type="nucleotide sequence ID" value="XM_060516011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDV0"/>
    <dbReference type="GeneID" id="85399909"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070917">
        <property type="term" value="F:inositol phosphoceramide synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006673">
        <property type="term" value="P:inositol phosphoceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013862">
        <property type="entry name" value="Kei1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28077:SF1">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE REGULATORY SUBUNIT KEI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08552">
        <property type="entry name" value="Kei1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="30048" checksum="54FD101CFB95568C" modified="2024-05-29" version="1">MALSRFNMRLPLPKVLCVRQTFLGCIGLQTGAEVISLILLFNRLTGLYGLLAILTGYELSVTQLSMYLYSLGVVVLLAMFMPHIRKQSPFETLSLAWLYIVDTILNVAYTTFFAVNWYLNSSALDKHPAGSTTPAAAGPAAAAEIAETALANGAPVVPDVPGTTKHIGPQESWMSLGLICSVTLVRVYFALVVMSFAQQVLQRYNAADMGWEEEGRSSGAGKKGGVDGPFSQGEPGGEGSRGRIGRVMLALGRGYWLRERPQEEWASAVSAKFRHTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UET0</accession>
    <name>A0AAD8UET0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_588218</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360216.1">
        <property type="nucleotide sequence ID" value="XM_060506114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UET0"/>
    <dbReference type="GeneID" id="85390013"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000072">
        <property type="entry name" value="Cysteine proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="8">
        <location>
            <begin position="130"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="717"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="853"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="742"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="766"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="796"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="884"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1715073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="954" mass="108606" checksum="6CF54BC7ADD0FB18" modified="2024-05-29" version="1">MPVTVTKTRKTKQQPPQEIIDEFWTKFTTKTPGKATTVIPQNAYAERVAKRSSKATGIFTQTSYDEAATVCKAKVDKIVHECRRVNQRYRDPHYDIEFDLKFGRRDCLETLWNTKDAKPPQSSFQPKAVKRVVDIFDNPQFYIDGPTADDVRQGRDGDCWLMAALCNLSNKPGLIEKVCVAHNLEVGVYGFVFHRDGEWFSEIIDDKLYLTKPDYDEPYLERILWEDRERINSEEAYRRIYQSNSGALYFAQCENPNETWLPLLEKAYAKAHGDYASIEGGFTGEAIEDLTGGVTSEVYTTDILDKEYFWKEKLLKVNEDWLLGCSTGFASRGLGERKGIIEMHAYSVMKAVEMDGQRLVLLKNPWGKGEWKGAWSDGSKEWTPEWLRKLKHTFGDDGAFWISYHDLLKKYNIFDVTRLFGPEWKVTSIWTTLSVPWTLDYHETYFAFTISKSGPVVIVLAQLDDRYFRGLEGQYRFDLQFRLHKAGQEDYVVRSQASYRMNRSVNVELDLQAGSYEVLVKLDAVRNDGVLPIDQVIRNNAKNRREKLIRIGLAYDLAHSKGKLVESPAEKAAKEAYEKRQREKRRSEIKCKILEEREREHYLRIKAKEKAQKQQARRIAQHQAAKEKLRANKRLVNPLPPKQSEPIPNPPSPVAKVTIQEDEPETLEIAIKNLSLSNDSRGTGSRTNSGIAAAEDVPISPRHKDRAIPQIFNAAEMLEQDTERGSGFLTPPKPANKHSRGDRREVVKVRSEVQEVTLQDVEEAMSEAAPPSEYSAPYPCESDDDGIASVSSMSELSERELELEIDAVEKREPSTDRLPPQPPPGAPAEEQDEFERDPWNAVAVVGLRVYSKVSDEDQEEVISNLRVVRPSLYPQEEAVPKTSEPGDKKSKGLDVDDSAKDATLEGEIKQRKKSIRPTSEDLSDASKLSRSDASRKRRAIPGADSLGYMFDFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEU4</accession>
    <name>A0AAD8UEU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_58017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360273.1">
        <property type="nucleotide sequence ID" value="XM_060505320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEU4"/>
    <dbReference type="GeneID" id="85389219"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042257750" evidence="1">
        <location>
            <begin position="26"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="105" mass="12003" checksum="B1CA1373D22DC4C1" modified="2024-05-29" version="1">MSGVNRPLLVALGLFLLFLLGFNKGRSVCLSVQVVFHFHDCMRYSLRANLKRAYSPHSQQPYPVIIIRHLRPSNGSPISEISHWIGNNLNQVLQLARYSRKSEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEY9</accession>
    <name>A0AAD8UEY9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotrophy-associated secreted protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359510.1">
        <property type="nucleotide sequence ID" value="XM_060514826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEY9"/>
    <dbReference type="GeneID" id="85398724"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042203371" description="Biotrophy-associated secreted protein 2" evidence="2">
        <location>
            <begin position="18"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="24258" checksum="0C0FDEC70A20EE3C" modified="2024-05-29" version="1">MVRFSLAAAFFAASALAIPSPLTPDPSGDKNVGNGNGVQFIGGACLNSKDCASTCCATLNGAGICSGLGAQFQAGKTGCGFGDGGAAAAPAASQGAGQAAPSMEAAAGSGGGAGSGTSSNVGAGNGQQFITGQCLSDADCASGCCNGPKGACAARAVATENGKAGCGFTGTGAGAATGSTGGGAAAEAAAPPQAAPSAGAGAGSAAGAGTSGAPGSQNVGKGNGQQFITGQCLSNEDCASGCCAGPKGVCSATAVANESGKTGCGFTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC6</accession>
    <name>A0AAD8UFC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_547784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360334.1">
        <property type="nucleotide sequence ID" value="XM_060503462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC6"/>
    <dbReference type="GeneID" id="85387361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="371" mass="39522" checksum="31364BB1D06ECB2D" modified="2024-05-29" version="1" fragment="single">MEEEKHKFIIPIHERRQPGTVTVDPNSVPSQPQHQPPTPLPSHEAQSPIDSSPRIQQIESFTSYPPGAHLRGDDIPDASPPYPESRISSEAPVVTPAPVPARGQSHHHHRVPAPALAPADPERQQGGTLAAWRQRFDGIGGRGPQQHPRKTILGLTVLRFWAAVALGVIIVGVAIAVGLALGLANRPSDDENEPKAVIQQLGVPSPAPINPYCPLATAGVNTTVTPYDASGSPIRFNNDEVMSFDVLCNTYYPMRQGINPYLRDILVMTVPDMLTCMTLCAQYNQGYSDAVGDDVFLDGGGICVGVALVKGTAQFCHLQNATGINQTTASGGFDVDSAVLSGQWASLTSVEQIRTFGGNIDDVIGANATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFL4</accession>
    <name>A0AAD8UFL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_704636</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362188.1">
        <property type="nucleotide sequence ID" value="XM_060511494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFL4"/>
    <dbReference type="GeneID" id="85395392"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="46612" checksum="B6C346ABE9A74AB2" modified="2024-05-29" version="1">MSAAAQRGTLAPLPEYHRRGLILLAYRKTRPDPRQRSTRPQDADITDLPDLSLGLDAPCAGASGFARIEELDRLAASQEQAAEAASATGDGEEQGAERARNPFPILIYNLLLADMMEAVAYALSISWVSADGIFAPSSVCWAQGWLGSTSNLAASLFLAVISINTFLTVGLGYKPPPWTIYTSIGFLWIFDFGINGAGVIFSEIHPAVPQESFFMRANVCEASESGFEPGHSLEVRRPSGYHPAFLAYPFVYVACSTPLIIGRIASLLGIDLGILYFAFAGSILAANGLFNSILWITTIVFSEPQDAHNTGLDQFAFVRTPIRDYGHTVIISGPVSRRVPEPSIVPSSGRKEWWWWKHGGQRGWGRSYANMHETPRVSAVEVHDRTLPVIVEGPYIQMDIVTAVTIEQAEIQPIPLGRHQETYPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFW8</accession>
    <name>A0AAD8UFW8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359975.1">
        <property type="nucleotide sequence ID" value="XM_060510842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFW8"/>
    <dbReference type="GeneID" id="85394741"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974:SF2">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="43048" checksum="AFE60DF1971C6D5C" modified="2024-05-29" version="1">MATSDLESKIRQAAVRNRQLLAILADTDNAIPDLRQQRRLITDLDHQLKESDKNIRALDTRRKKELKDHEKFRDSVMRRFVHKAVGKRDKFDERAAREEREYFDVLQDEHREKELNKNVKEQLSDAREASKALEVEARRHDEAQCELDSLYDSIFAGPTPSYPEEDTLEQSAEQALHEYHDTRSKVEAEQHAIRLLTDAMKRMGDSLRHMDDALSHSRMDMFGGGTMTDMMERSALQRAESAAQEARMLVMQAQRMTPYIGDLPPININHGNLMGDVLFDNIFSDMAFHDEIKKSRMSIEKCAQVLSRYLHETRDRHMYLSREQKVRGERLESTRTALQKERERLFEQIAGGSSDMKFASASSSAMPVGLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGB3</accession>
    <name>A0AAD8UGB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_795309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361245.1">
        <property type="nucleotide sequence ID" value="XM_060515836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGB3"/>
    <dbReference type="GeneID" id="85399734"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="188" mass="20351" checksum="4B5B8B2DFDEB1337" modified="2024-05-29" version="1" fragment="single">MLTALVARSRTSTQSFTITILTRMETSKTAKWIVTLLALRSPLWETMRISSAGVQTLTARIIHRVLFSRRCQTPTPLFATLLVPTTILMLVEETMAAISSITSMGTTTTTTTSSSSTRSTTTSTTTTSSTRTSTSTSAGPTNTLQHRAPRFRYSYRGCGAISNFGTVGTNYIYAIGNATQCQQSCSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGG6</accession>
    <name>A0AAD8UGG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TodF product hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_795296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361229.1">
        <property type="nucleotide sequence ID" value="XM_060515835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGG6"/>
    <dbReference type="GeneID" id="85399733"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008684">
        <property type="term" value="F:2-oxopent-4-enoate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050772">
        <property type="entry name" value="Hydratase-Decarb/MhpD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30143:SF0">
        <property type="entry name" value="2-KETO-4-PENTENOATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30143">
        <property type="entry name" value="ACID HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="77"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="28405" checksum="3C19B288D707C815" modified="2024-05-29" version="1">MRDSELQEISSALRAARISKEPIEPPTKKWTSLDPDSAFEVQKVTVKNAVSQDGDRVVGYKLGNIAKVMQDAFGLDQPDYGFLLASTFIFEGTVLSLKDFIKPYVELEPAFVLKGPLRGPNVTVADVINAIDYAIPAIEIIDSRVRDWAIDLPDTLADNGSTGAVILGGSPRRLPDLTLSNTRGTLRFNDKEVMSGNTRNVLGNPLSAVAWLANKLAGYDVGFDAGQVILPGSCLQAVPMQEAGRWSCTFEGWGTVEFDVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGI2</accession>
    <name>A0AAD8UGI2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_628248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362758.1">
        <property type="nucleotide sequence ID" value="XM_060508683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGI2"/>
    <dbReference type="GeneID" id="85392582"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF29">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="37758" checksum="C1CFABD6D4119320" modified="2024-05-29" version="1">MSSHEKKILVVLGATGNQGGSVVRAFLNDTTLSSYWHVRGVARNPSSESAVKLSNVGAEMVSASLGSVSELKSAFEDATAIFAVTDFWSAIKTEEVRHRVQSEGIDLAIATQDLEETWGRNIATAAAGISTLERFIFSSLPPVSQLSQGKLKHVHHFDGKANVVQYIQQNHPTLWVKTSQILVGFYNSNILSDSYFGPNFNPLTGKTEFEGPVSDDNLIPFIDAPSSTGNFVKALILDVPAGTILAAYDEMKSLGECVEFLRRETGRDFVFVQRNVDEMAAESPLGREAPESWVWLAEYGLFGEKVEGWKEFLTLPGGLESQIEAVKMDEWLSAQDWSKAFRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGM3</accession>
    <name>A0AAD8UGM3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thiol-specific monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_586485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360979.1">
        <property type="nucleotide sequence ID" value="XM_060505955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGM3"/>
    <dbReference type="GeneID" id="85389854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000138">
        <property type="entry name" value="Flavin-containing monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1717492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="52785" checksum="9C3E3C5CAD1ADE13" modified="2024-05-29" version="1">MSTISFTVKKIAVIGAGPTGLAAARYLTAQGAFDSVVVFEQQAEVGGVWNYSPHPTTSRHVPQTDPFCPQDPPLRPGGSGAPPVFPTPMYGTLHANTVKTTMNYKDTPFPDDAWVFPSRQSIYNYLVEYAKNVRHLIKFSHQVTALELRQENGRDRWDLVAACTVTGRKFSDMYDAVVIANGHYDIPFIPDVKGIMAFHEAHPSAILHSKNYRVPEPYSGKKVIVVGNGPSGLDIARQLSPVSDRVYLSVRHATPPDKVEHVGVTEVPEIVEYLPEKRAVVYKDGAVAEDVDAVIYCTGFFFSFPFLPEFLKSNLLTTGKGVRGLYQHLFLIKHPTLAFAGLLVKTVPWPVAENQAAALGAVWSNGLKLPPVEEQEEWELDLFKRRGDKNIHVLLDDGDDGRHLNMLHDWVAESTQRGKEPPYWHDEQFWERGIYWPSKQEFEKRGGSATSLRELGFVYPGIGQWRHVAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH25</accession>
    <name>A0AAD8UH25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360530.1">
        <property type="nucleotide sequence ID" value="XM_060506055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH25"/>
    <dbReference type="GeneID" id="85389954"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039510">
        <property type="entry name" value="Vint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032838">
        <property type="entry name" value="Vwaint_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF156">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14623">
        <property type="entry name" value="Vint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14624">
        <property type="entry name" value="Vwaint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="43"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="711" mass="77320" checksum="BE27769090633ECE" modified="2024-05-29" version="1">MTEYDTSDGVALSLHAFAGRDGILAKITPPRQPVKPTVHVPCDIVLVIDVSGSMGANAPIPANPGEVAENYGLSVLDLVRHAALTIVETLDEGDRLGIVTFASQVKVVQELIPMNKKNKGLAKKNIKKMVPTDATNLWKGLMEAITLFNRKSDEKSERVPAMMVLTDGQPNLMCPGQGYVPKMREEVKLLKNERLPASIHTFGFGYNLKSGLLKSIAEEGGGNYAFIPDSGMIGTVFVHAVANLQATYAIRATLRLTCSSLLTIEEAMGESVNKQEVEILEGDMENGIPDQHELSILLGNLQYGQSRDIYLRVDAPAELTSDHAVVKASIEYSRMANNTYTQSTSQSLLNPTTLPESELVYHLSRSKICSFLSTIIPMAPDGEHKALPRISPEKIQELKALIKDIPAKRFPSDPNNKSLIEDLEGAQPKGQVSLALTNREYYKKWGVHYIPSYLNAHTRQICNTFKDPGPLRYGVDSPLFIACRNRLDHAFDSIPPPTPSNQHTATHRGRVHMSSYNSSSGVCFISSTPVRLASGQSVPIKALRRGVAVQTPSGPRRVVAVLKTPVQREIMCRVGELVVTPWHPLSLDGGKTWTFPANVADRPVRYTGCIYSVLLQPGRDSEAHAINVAGTWGVTLGHGIVTGQDARAHQFFGNYGKVVRSLRKIRASKKGVAVGGGVNRDSVTGLVSGFAPHREADVAVKRVANNAICVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH95</accession>
    <name>A0AAD8UH95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_467036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361294.1">
        <property type="nucleotide sequence ID" value="XM_060503265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH95"/>
    <dbReference type="GeneID" id="85387164"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="18769" checksum="738A6C57FC883A37" modified="2024-05-29" version="1">MGHSGHRRNTKKKHVGCHSVAFLSVCFLLGNLMMARSFHFPSLESLTLGRVASSRLTLPLPWLRLAPGPGGLCSRHRDSKPTATQPMGPSARERCCVWAGPTHGCVDRVVRSPGPVQFRRAEEWESISATAVRVRRALPYRNATRGLLSGTAARIAGEETTSPFDRSNRGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHA7</accession>
    <name>A0AAD8UHA7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA splicing factor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_543897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364332.1">
        <property type="nucleotide sequence ID" value="XM_060503429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHA7"/>
    <dbReference type="GeneID" id="85387328"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="23806" checksum="BB4FD201BB4AB1ED" modified="2024-05-29" version="1" fragment="single">MGGDLNLKKSFHPSLIKNQAKVWEEERKALDERKKTQQRINELKEEREREELQKKLEAAGHTKRVDRVEFLYSGPTDGQTGTTEERESYLLGKRRIDNLLKGTEHKNLEKQAGQESFMALQTANTARDTAAKVREDPLLAIKRQEQAAYEAMMNDPIKRRQLLASMGMADDKSKKGKEERHKRRHHRHRNDDDDRERHRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHD0</accession>
    <name>A0AAD8UHD0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription initiation factor TFIID subunit 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_755077</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361638.1">
        <property type="nucleotide sequence ID" value="XM_060514566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHD0"/>
    <dbReference type="GeneID" id="85398464"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000037">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="8">
        <location>
            <begin position="645"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="318"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="445"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="407"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="107"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="318"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="564"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="759" mass="80290" checksum="65DF6129BE53C91B" modified="2024-05-29" version="1">MNNQGQPGQAAAGQTVPSARQPPMYRPEMMRNLPILNDEEKQKYERGLRQLWNHYETHPEESAQHQDAKKKIQDFTKMLLNKLQQRRMQVQQQQQAQQQAAQQQQQGGQQTQQQQSQPAQSAAPAQQAQPAQQQAPAAAASQANVGGVTIKTEPKTENTATTTAEPAHAPTPAPAPAAAAPTPTAPQQAPQATQFADHILAHIRQMTFNPPQGILDKGQEAAARWSNDFKAKYLRALMQMDQQGIQIRRIDAHVKNQQEKGALGADEAKQLQIRRDHAQKMHTEAQTFVQNFRKSQEGINKARAAVAAAAAAGQTAASASAAAQQRPPSQQQQNSPAVAASQPPSTQPGGAQASPAPTAQGTPATQNAQNPTTAVNAAIEAAKNQQMTGAAAAGQGTPPQQQQQLPQQQVQQQQLQQQQQLQQQQQQLRQQQLQQQQAQAAAQAAASSAATPTTSQAPQAQQPMASAPQQTMNQGQHHPPPVNTAIASVSAGGGLPSAGTPTQRVATPQSAAPAGPGQALSHSAAVSRANQRNVQTSAPIQQATGTPGSAGAHAQGVMGSGAVPQQQHAHPTQPTQTLQSKLPIPKQLPEKATSVPQPVAMAGGAGAGRPTYTGGGGIAGGVMGQPAISKIPAYVHEAEGDHVLSKKKLDELVRQVCGGNAEGQEINMLTPEVEESVLAMADSFVDNVLETACRNAKERGSKVLEIRDIQLVLERTYNIRVPGYSSDELRTVRKIQPSTAWITKMSAIQAAKVTSGKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHS9</accession>
    <name>A0AAD8UHS9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_584592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361848.1">
        <property type="nucleotide sequence ID" value="XM_060505774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHS9"/>
    <dbReference type="GeneID" id="85389673"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04081">
        <property type="entry name" value="CBM35_galactosidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000197">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042206576" description="Alpha-galactosidase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="9">
        <location>
            <begin position="320"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1720337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="59184" checksum="5407E828512EC779" modified="2024-05-29" version="1">MASVAFTLLTALAARASAKTHKTPTPQMGWNSYNYYNCYPNETLIKENAHALINTGLADAGYTTVTTDCGWPAKERSADGELVWNPELFPSGGGKELGDYIHNLGLKFGVYSGGGYYQCGSTDQPASLDHELTDAKSFADWGADSLKYDNCYAVEPTVMVDYVSEEAVSPDRFVAMADALNTTDRDILYQVCQWGTGTDLGIWAPKIGNSWRISNDIYNGWRSIWRITNQVVPFYKYTGPGAFPDMDMLLIGLSALSIEEEKFHMGMWAINKSPLTLGAPAIPGLVPESAHEILVNKEVIALNQDPLAKQTELVRRYTEEEWDVWAGELSGSRLVVGLANWKNDSQAVSVDLAAVLGVASANARDVWAASDIGSISGTYETTLKGHELKLLVLSDLSTTAPAVDASAGYYTATAAALSGSASKVTCAEGQCLPSSTKVGNIGSGAAVKFEGVEAKSEGKKLLGVDFINYEIALDSAWQFGSNTRNLTISVNGGTEKRWAFPISGGNWFDTGRLLVEVDGFKGDSSNTVEFKSFGSAWAPDLVGIEVFEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIK8</accession>
    <name>A0AAD8UIK8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H3-like centromeric protein CSE4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">CENP-A homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">CENPA homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_583203</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of centromeric nucleosomes, where DNA is wrapped around a histone octamer core. The octamer contains two molecules each of H2A, H2B, CSE4/CENPA and H4 assembled in one CSE4-H4 heterotetramer and two H2A-H2B heterodimers. Interacts with the inner kinetochore.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362400.1">
        <property type="nucleotide sequence ID" value="XM_060505630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIK8"/>
    <dbReference type="GeneID" id="85389529"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000087">
        <property type="entry name" value="Probable histone 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="36"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1722345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="134" mass="15451" checksum="E39C9FD3A9AA07CE" modified="2024-05-29" version="1">MPPKKRQSDAVRRKSRQSDVQPGDPIPNRGKRRYRPGTVALREIRRYQNGTDLLLQRLPFSRLVREIAESVRPRGEAMRWQSQAIQALQEAAEAFLVHLFEDTNLCAIHAKRVTIMQKDIQLARRIRGVWGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIR8</accession>
    <name>A0AAD8UIR8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361325.1">
        <property type="nucleotide sequence ID" value="XM_060514604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIR8"/>
    <dbReference type="GeneID" id="85398502"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="20323" checksum="CDBFD42A7F395D6D" modified="2024-05-29" version="1">MSPSERPPTARGMSANHATPANRKRRPSANNTPSTSPGNAPADFEKIEAVLHPSCPVHGRHSTSGVRPPENAAAQETSESSDLALRRSLSTPATANGSAVQFGSIEGSISQNPRFSAIVNKQPSDVTSLSETVGTVSTISRSPSTPFFEPKTPTAMVIIRDLEDAAFGIASQEKETGLAELRCVDRNMGVSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIW5</accession>
    <name>A0AAD8UIW5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_418584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362595.1">
        <property type="nucleotide sequence ID" value="XM_060502966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIW5"/>
    <dbReference type="GeneID" id="85386865"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="189" mass="20714" checksum="8F196419E82D4E13" modified="2024-05-29" version="1">MGRPCFMLLCSNRHVPFWVFYSAHCFLFRLMSNILQALSCFVPFPPYVSVVYFVPPTFSIIPAPDAMSSVINECTLSRSLYIPPWCKAHTHVHPSPSLDVSPPTNAPITTLSLSPSAKDLPTCGPVCPGPGKAPRKCQAPKRREPPPTLPYSSAWVPLVASDTTMILAKTRDMPRCARVRKPSPPPGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK97</accession>
    <name>A0AAD8UK97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_581220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363360.1">
        <property type="nucleotide sequence ID" value="XM_060505436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK97"/>
    <dbReference type="GeneID" id="85389335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03046">
        <property type="entry name" value="GST_N_GTT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF9">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="98"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="27371" checksum="B27D940A3CFD65B6" modified="2024-05-29" version="1">MSIEVYHLGLSQSERIVWLLEELQVPYDLHVFQRDPITGLAPKEIKEINPAGTAPYFRDSTVSPPIELGESGATVEYILNVHGSKAGSGAPRLLRTPDDADYAAYLEWFHFANGTLQPTLGRAMTLLFAGASQSDFGKRMEEKSHQALKLIDNRLANNKWLAGENLSAADIMTVFTLTTMRGFYPLLDLSEHKNILRYLKDVAERPAYRKALEKGDKGMEPMNGPKVKAFKQFKGFGAIYESLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKI0</accession>
    <name>A0AAD8UKI0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-1,3-glucan synthase</fullName>
            <ecNumber evidence="2">2.4.1.183</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_575307</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19749"/>
            <dbReference type="Rhea" id="RHEA-COMP:11150"/>
            <dbReference type="Rhea" id="RHEA-COMP:11151"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28100"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.183" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366042.1">
        <property type="nucleotide sequence ID" value="XM_060504796.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388695"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047657">
        <property type="term" value="F:alpha-1,3-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070600">
        <property type="term" value="P:fungal-type cell wall (1-&gt;3)-alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11323">
        <property type="entry name" value="AmyAc_AGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000058">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000073">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000052">
        <property type="entry name" value="Alpha-1,3-glucan synthase Ags2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058659">
        <property type="entry name" value="Mok11-13/Ags1-like_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058656">
        <property type="entry name" value="Mok11-13/Ags1-like_GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058657">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058658">
        <property type="entry name" value="Mok11-13/Ags1-like_Ig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058655">
        <property type="entry name" value="Mok11-14/Ags1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058654">
        <property type="entry name" value="Mok11-14/Ags1-like_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182:SF2">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47182">
        <property type="entry name" value="CELL WALL ALPHA-1,3-GLUCAN SYNTHASE AGS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26127">
        <property type="entry name" value="12TM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26122">
        <property type="entry name" value="CBM_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26108">
        <property type="entry name" value="GH_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26114">
        <property type="entry name" value="Ig_2_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26111">
        <property type="entry name" value="Ig_Mok13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251907" description="alpha-1,3-glucan synthase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="2346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1055"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1922"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1954"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1980"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2015"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2047"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2087"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2133"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2170"/>
            <end position="2191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2198"/>
            <end position="2215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2272"/>
            <end position="2290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2318"/>
            <end position="2338"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="68"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1656"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1845"/>
            <end position="1890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1685"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1695"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1852"/>
            <end position="1865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2346" mass="261389" checksum="FDB9E5E2217750BC" modified="2024-05-29" version="1">MSNSVLAWALTLLTTSSTLVSGLKYTASEVDYNLNTNRLAKSPAEYSGKRDGHTFTKSPPNWRFPYYTLFIDRFVNGDPDNDNANGTLFEHDIMSNQLRHGGDLAGLVDTLDYIQGMGIKALYIAGSPFINDPWKADSYSPLDLTLLDKHYGNITAWQEAIDEIHKRGMYVVMDQTMATMGDLIGFEGYLNTSTPFSTSEHKVQWKTSRRYLDFDIGNEYNDSCTYPTFWFEDGNKVDVSSQLKGCYDSDFDQFGDIEAFGVFPDWQRQLAKFASVQDRLREWVPSVRQRLELFSCMTIQTLDIDGFRIDKAVQVTVDAQAEWSTAMRKCAKDLGKENFMVVGEITSGNTLGSIYLGRGRTPSMASALELSDATTLDSNSSSTSGSFIREQGKSALDAGAFHYSIYRFMTRFLGLSGHLEAGYDLPTDWVQTWNQMILTNDFYNANTGEFDPRHLYGVTNQDVFRWPAIEKGTERMLLAYFITTLLLPGAPLVYYGEEQNFYVLDNTAENYVFGRQAFSAAQAWKAHGCYAGNNSVYVGWPVTKGKKGCEDETVAYDHRDPSASVRNWMKRLFSFRDKYPVLEGGWLLEQLSNKTHGVLYSGSPTATETGIWSVARGYMSNQNKTDDPVWLVYHNSPNETTYEFDCSNEADAFLSPFDGNTKVRNLFSTDASITLESSTKENGFKGAGHKAGCLSSITMTPFEFRAYVADTEWMEIASSITGFEPGHDTPIDSTDANGKIPIAFKFSTEMTCADVTKAVSAYVNVDANTQTNITFDTPVCGAMDPIEKESWTGAIASVWKWSANLQNVPDGIVKITVDGVTNTTDHFLLRFGKPINPVVFPASANYSRSLMQQSGTEYFINHAAPGANKWRYSTNWGSSWSSWMPYTGARQRMVPQAWEGTDLQKWEGEHLMVQYFSKPLGSSSFIQHADNSVIPFSRRFPHIFLHGPFNKWGYDAGLPNLMTQVGDNMWELHFMYEWPAQIQLNLWGINPDNQPDASFIYGDPNGDGVLDRLPPSSLSDNVVNLTSPPPMPALSYKLVLNDANWNYVAVPQGNMWIQIVFFFLLGLMPIILAGLAGWIYMKGFYQVKINKSGFSKKGWLPLKLGNESNINFGEKGKSLEMSQIPPSPTVTPAAVAATGGAPRRKVLIATMEYNIDDWKISIKIGGLGVMAKLMSQALSHVDLIWVVPCVGDVDYPMDHEAEPMFVEVMGDSFEVKVNYHVYKNITYVLLDAPIFRQQTKADPYIARMDDLESAILYCAWNSCIAESIKRFNADIYHINDYHGAAAPLYLLPQTIPVCLSLHNAEFQGMWPMRTEEEQKEVYSVFNLPAKVVKDYVQYGSAFNLLHAAASYLRIHQRGFGAVGVSKKYGDRSLARYPIFWSLKNIGQLPNPDPSDTGEWNPEEDISNSTDEIKIDETFEANRATLRRQAQEWAGLDVNPNADLFVFVGRWSLQKGVDLIADLFPSILEKYPSVQLIAIGPVIDLYGKFAALKLAKLMEKYPGRVFSKPEFTQLPPYIFSGAEFALIPSRDEPFGLVAVEFGRKGALGVGARVGGLGQMPGFWFTVESMSPQHLLHQFKQAIASALACKPRKRALMRAWSAKQRFPVAQWIRQLDTLYNDSIKVHNKEAAKQKKAGGIRNLTDSSLRSSIAVSEYGAELTPTGSRAPSPLPPPSRIASPAGRLNSPDLQTPNMPWSTISSSRRSSFSSSIGGRDSMLAPRDSMFASGRESMVSVDSFAIRAQNDVSSPQTPGFGDALGLPQPSFYKQQRNSSQLSLPDVVGDRHDLKLQNVDQNFTDKNGEFYAEFEQMLNKLTAKNSGTDLCIENYLKKSEKKWFARYRDAKLGRRDHSRSRSPAPGSRPGSSKGLGAKFDVDERGRSRTPSGLTGASRYDDSPVDDEFLLGDNYNAPTGLKKILSIRIGDWPIYAFFLAFAQVISINSYQIVLLTGDTNQTPLKLYIVAATYLVTSALWWILVRFTKSVYALSLPWVFFGLAFALLGISPYLTPWQASAAMQDAATAIYAAGASAGALSFALNFGDEGGAPTKQWITRALAVAGVAQVYSLMLWYWGSLTHTPETSPLAFFDGTNISKGIVVCIPIAIMLWSIGLVLFFGLPDYYRQAPDNIPGFYISLARRKLVPVFFIMIIIQNYWLSAPYGRNWGFLFASQFIPGWGVVLLALGFFVVLWSIILYVFSFFSESHTWLLPIFAIGLCAPRWAQMLWGTSSMGMYLPWAGGPVGSAILSRCLWLWLGLLDNIQGVGLGMMLLATLTRQHVLAVLIGAQIVGSAFTMLARATSPNALSPNTTFPDFSQGLMPGVSSYWFWICLGFQLVIPILFFKFFRKEQVSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKN2</accession>
    <name>A0AAD8UKN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_775202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366132.1">
        <property type="nucleotide sequence ID" value="XM_060515438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKN2"/>
    <dbReference type="GeneID" id="85399336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="15456" checksum="2D5E3DFF6A36F55C" modified="2024-05-29" version="1">MASIHQGKPLISAETLMHDCDAIISATLDFLEGEKQKGYKNIHVESLEEKLLAQKIFFGFCKTTYKERRAGSRNSNEDNILKKLNPVKTNFKKVQDELEALLQADKEGALEDAKEKTEVAFAELAGSVERLKAIFLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKU4</accession>
    <name>A0AAD8UKU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase FSH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_330479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364742.1">
        <property type="nucleotide sequence ID" value="XM_060502412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKU4"/>
    <dbReference type="GeneID" id="85386311"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF4">
        <property type="entry name" value="ESTERASE ALNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="29143" checksum="5E09F9FE69BDC23A" modified="2024-05-29" version="1">MLRFLCLPGAYGSSDKFQVQLAPILKELTEDGTAQFHFIHGPCKAVPPPGFEDYFGAPPYYRFIEPDRDVEKSHSDDVLMRIRDFPDCETPEDTMRELMREGIATTHRSTDRAIKFLADIVAKRGPFDGIIGYSEGATVASTFMLYEQRRLKRSGIKPAFKYGIFFAGWPPVDPKTHALVLSDESEERIEARTLHIIGSLDPYVDGSMALYNMCDPDTAYLFDHAKGHTLPRDKDTIKELGDIIRETQADMQEEGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKV0</accession>
    <name>A0AAD8UKV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_625916</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363629.1">
        <property type="nucleotide sequence ID" value="XM_060508522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKV0"/>
    <dbReference type="GeneID" id="85392421"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="513" mass="58081" checksum="3AD47E272273DF03" modified="2024-05-29" version="1">MSFQEQISNMRGTNDALFPPSLHGSIALFALIPLSIWYLLSWYRLRHIPGPFLNSLSILPMQHMTRGGKLSFMLKDLGDKYGPLVRVGPNEVLFGDPDAYRKISAVRSDFTKGPWYALAKVVPDQDSLFSMRDDDLRKEYRAKLSPGYAGRENGGFEPGVDRIVAQFVNLVETKYISTSKEFRPIEFSHKSQYFALDVVSELSFGEALGFLANDEDLFGYVATNDLIFPYLAVMLNIPWVGIFMQQWPLNKLLPFSSDEFGFGKLMRMAKSLADKKLAAVTDENNMVQQHLRNGVTYKELLAEIFLELIAGSDSTATAVRMIMLCLLNTPSSLNALRREMDQGIAQGRISSPIRDSEARQLPYLQAVIREGIRMYPPSTGLNYKQVAKGGTELHGQFLPEGTQMGVNIQKLMRSKDTFGCDADVFRPERWLEVAAEDEDRFREMCGVVDLAFGHGRFQCLGKTIAAMELNKIFIELFRRFDFAVVTPQEPLKLYDAAFWVTTDFWLRVLPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULQ8</accession>
    <name>A0AAD8ULQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_624938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363918.1">
        <property type="nucleotide sequence ID" value="XM_060508474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULQ8"/>
    <dbReference type="GeneID" id="85392373"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="60" mass="6845" checksum="BB0DB552B144A8C9" modified="2024-05-29" version="1">MIPTADHFFFQSSKPTSLDSQPNSPHKFPKKVANWECESNEIPSPPVWPMAALRFSWDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMM3</accession>
    <name>A0AAD8UMM3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_781977</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363200.1">
        <property type="nucleotide sequence ID" value="XM_060515553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMM3"/>
    <dbReference type="GeneID" id="85399451"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="29"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="384" mass="43193" checksum="151EDDF15F5DBAF5" modified="2024-05-29" version="1">MMAPIESNGPLIAGITWFLCFFCGAFLALRVYAKLSRGQKLWWDDYIFLFSWTCLFIESIITQMGVNLGFGRHYYDITPQTNLLTIAMYTSVGASISCFASTGSKVGFGVTLLRLTTGWFRIFVWFAVVTLTVVMLPSATLTWLKCTPVQKNFNRQMPGTCWDESVTLNYGIFNAAWCAFMDFVLAIIPWKLIWGMRLRKHEKLGVCFAMSLGWLAGVCAIIKGIYLVQLEQGDFFFNGKDVTIWTAVETATAIIGSSIPVLRVFIKEKASTLGYDNKVNQDHSNENSNNMELNTYRSMVTSRTGKSTLSTTEETELYGARNLPRSGSCLLVDIPDFKLEGIVRARSVDEESQGGSDDDKIYNHDDRIDLNVHSQEQIRYVGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX2</accession>
    <name>A0AAD8UMX2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_752561</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364548.1">
        <property type="nucleotide sequence ID" value="XM_060514218.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398116"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="876"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="966"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1063"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1098"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="249"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="562"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="844"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1158"/>
            <end position="1415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1415" mass="154309" checksum="4A08B1BFD21C2C20" modified="2024-05-29" version="1">MLSTSLILSTTASALFLLLLPFRLSKLRKETIKVIPEHHGHGKVIVSIILVVVQSTILATTALSTPRLRLNLASAILSLVSYVGLCPLLLLEHTRSVRPSDLAIVYLLASSGCDLVDLGTGVFDNGSAISAAPTIASLCIKGVLLVVELRGKQTILQGPRDQWSPEELSNILDRTFFGWINPILARGNRYILTGDCLPMMDSKLSSQVRRERALRAWDQRDKPEKRMMLPKVLLRSILPQFLAPIIPRLVLIGFRYAQPVLIGTVIRSISKSSDESQDGGYSVVSMAVFVYVGLAIARTAYQHSINRLKIMIRGAVVGLINNKQLSQRSTGYGDAKAVTLMSTDADNVVQSASMFHETWAQIIEVAIGTVMLARRVGCVCAVPFLMIFFCSRVSRYLAKNLQSKQKNWSVATQNRIAMTTSMLCSVKSLKMLGIVDHTESLILSLRLRELEMAKKVRWLMVAYNASANALGIFAPILTLVLYVIVARLNGSALDVETAFTTTALLGLVTHPANMIMTIVPQAVGSLAAFERIQQYLAEPPREDQRLLFDKAEDSLVDVSPAMSLEDVTIQGLTTSKSPVLSNLNLVIEKGSIVMCSGPVGSGKTSLVRVLLGEVPPASGTISVSTKRIGYCEQSPWLPNGTFKQAVCGFLPEEPSWYQEVIQLCCLDEDLLALPGGDNTVIGSRGLNLSGGQRQRVALARAIYARSEIVILDDSFSALDGRTRSHVVENLLGSAGCFKKTGTTVLLVTHSTAHFKLADKLIILGGGAIAYQGTWDGLKQHPKYSSLAIDIEGSKSDTAVEQPQVDKTVQSQNLKMAEAVSDLSRATGDISLYGYYFRAVGFRHILLLLACTSTYSFFVTFPQYWLQKWTEAPVSQTTFYICGYLISSLLAWIATSGTMWSTQILIAPASGIKLHRRLLSTIVSAPLSYFSKTDAGVTLNRFSQDIQLVDKQLPPAIMSMSNQVFKLLVQVVLLFSAQKLLVLSLPLCAAVVYLVQRVYLRTSRQLRLLDLESQSAVYSSFLESVEGVTTIRAFGWEKQAEHANVVCLDKSQKPAYILFCLQQWLGIVLDLMVAAIATGLITLAIFVRGTTTAGQIGMALNIVLAANATLLSLVTSWTNMEISLGAISRLKALEADTPKEDQPHEDFVPTEVWPSSGSVEFDKVTVSYNTDAVALRDITLKASPGQQLIICGRTGSGKSTMLLTLLRLLDTDAGSIKIDGVDLRRVPRSLIRQKCFITVSQESFILGHASLRFNLDPSTSLPDEAIISALARVSLLSHFHLQDTSSEEEIRNTLDSPLSSLPQMSTGQSQLFALARALVQLYSIIQTSESPANGTGGRHIMPVLLLDEATSSLDTETESAIRNIIYQEFTDKGHTVIAIAHRLGGVTEGMRPGRDAVLLLSKGKIEKIGEAEDVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN96</accession>
    <name>A0AAD8UN96_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364476.1">
        <property type="nucleotide sequence ID" value="XM_060514232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN96"/>
    <dbReference type="GeneID" id="85398130"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="37683" checksum="04F91248AC3AE3AE" modified="2024-05-29" version="1">MFGIQHHPDLTRKRGRDDEEDMHNGTLSFGEHRNKRLQCLPLRTSPTSSKRWSTPVIPLNAAPCTLTPGDSDSEEQPRSHFSPWSSSPAPMSCQPSPFGPTEPDRDMDMMDTMSPPPIPQQHIQSDQPASVNGRMPTPIQPNFSSQFMNGGSSARDWRGPGPAVSHRTGVVNMGHMHAGFGSDESRSIPRTMEGTDDWHAVQNRRLPSPISEGEDSASHLGSGSLSPPGMVLDNGFPSNLTARLEQSSLNGHGHHDMGMMEVEDHSHMMSDDPVTTTIDAAPLETTSAPATPSPGRKGHIRSRHTVNSWTWQPGMKKSFSIGYRADCEKCRLKVPGHFNHIVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP12</accession>
    <name>A0AAD8UP12_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Surfeit locus protein 6-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_621937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364851.1">
        <property type="nucleotide sequence ID" value="XM_060508299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP12"/>
    <dbReference type="GeneID" id="85392198"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="5">
        <location>
            <begin position="361"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="344"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="515"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="589" mass="64953" checksum="2778710B6AF1A0D7" modified="2024-05-29" version="1">MAESTLQDRLREHSKAFDGLLSLIPAKMYYGEDNSEQWKRTKQTKAEAKAAKTAKLDPDSELNRNAKEVMDERAARNKRKLEAMQEEEDKEDEEPIPGVQRELPGQGLRMNKDYKKQKTADLPIDTIDDANPAEMSQNQLMRMAKKEAKLEKRATKKAKKAEKKAAKLEASGGDAAAAADADADAEAPEAKEFSKPAATKAAKSPAAAKKESSKKQQKKAESKDAKPVSNDHDRDVDKDEDEDEEYETVDESDDEAEPATKSKSKSADLNPLDLSGLAQQQKATESSGASASASPTFDTAAATASTTTSTSSTVPPSEKPKHIKLPADTSALRARLAARIEALRAARKADGPDGKPIRTRQELIEARRFKQAQRKEHKKELRTKAKLEEDARREETLASNSPSVMSPRVGLGGDDGDEPANFAFGRVAFEDGTKLSHDLSHALNTHKKRGPSDPKTALIKIQNQKKRLAALDKEKQADIAEKEQWLIARKRAEGERVRDDEQALKRAVKRKEQTKKKSEKAWKERSDGVAKSIREKQKKREDNLKKRKDDKLAHKLGRKSGKKVGGGGAKKTKARPGFEGSFGGGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPQ8</accession>
    <name>A0AAD8UPQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_619691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365538.1">
        <property type="nucleotide sequence ID" value="XM_060508144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPQ8"/>
    <dbReference type="GeneID" id="85392043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="26797" checksum="5CEFDDE9514F6D23" modified="2024-05-29" version="1">MGQFTSQPRDGASPSPNTVLGPSQGPDGPDQGIPVVTRIRTEGGKTATVTITLQETALTSALASTFTTSSLLPVMTTMMTTMRPSLTASTLSSTEQNTPLPNSTGSPDQEPHVTLPRNTLIIIISAAVGSVLFSLFLIGMIHAYVRRRHAIKEDAKKEAAAVGIQEREQDQSSHQHVNEVGYSMAMSQPAPRACSESDLYQHFHPSNEAANASFHTLPAAYPAYELHPTRVAAELPAEPHGSGLPHYGYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQE3</accession>
    <name>A0AAD8UQE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">6-phosphogluconate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_574606</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366450.1">
        <property type="nucleotide sequence ID" value="XM_060504726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQE3"/>
    <dbReference type="GeneID" id="85388625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015814">
        <property type="entry name" value="Pgluconate_DH_NAD-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF2">
        <property type="entry name" value="CYTOKINE-LIKE NUCLEAR FACTOR N-PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09130">
        <property type="entry name" value="DUF1932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphogluconate dehydrogenase NAD-binding putative C-terminal" evidence="3">
        <location>
            <begin position="207"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="34181" checksum="54D74AAD27E999C1" modified="2024-05-29" version="1">MTLSLPKIGILSIGDMGMGIAKLLVSKGFSVATNGHGRSRATIARARSASVEVLSSDVHLVESRRFILSVAPPRDALSIARRIIDAAASMKLEKPLYFTDLNAVSPATCKQMSQMFKEANSPVRFVDGCIIGGPPKLKSNSAADQWYVPSMPASGQYPISEASPELAEVLNMRHISPKVGAASGLKMCFATTTKGFMGLAIQAFTTASKLGVVDELRKEMSEAAPGLLDFAEKSVPLVPPKSYRWVREMEEISDTHRSEGGFEAENDVFLGMAELYQAMADDPVLGAEKVGERKRGTTIDDLAAALGDGLATRKQDKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR28</accession>
    <name>A0AAD8UR28_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366359.1">
        <property type="nucleotide sequence ID" value="XM_060504727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR28"/>
    <dbReference type="GeneID" id="85388626"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="467" mass="50566" checksum="D4A2A29B9AC5D551" modified="2024-05-29" version="1">MAPQQNTFAVIPDAPGRVGGPANRPPMTSKQAQKLYKQANKEPKRSKAEQRKWEKEKQEEIRKELEKERAAVKAKAARERKKAKEEEARENRRRAGQPLFDCRPSQDTIARFVRGNGTHKKRDSSGEPIPKPETASAALADIEPDTLASTAASKPPLQIESSEETKPSIASMAPPPRPTQITKSAMSPAQGATTSERQPSAEGVAPKPTDKDALTRQLLKPLFTAPEKAPALMASMGPPPRPAVKAKSRPFMMPKAALPTHQPPRHKIFKQKPSPQPSVQLKTEVSLPKELSYPKSALPKSSTAIPSPPVPSQKPRIEAVGDKAPTDISIPTIAPSPGVQSKQMLPPPRPSISQMPPPSTQAIVQDCFDDFFPTASQLAVELEEDFDGKHTMPRAVFGPKSNTHGAIAAAHSTPLDLMMSSQEVLDIESPAKAMTQLSSGGPVTNPASPLFEMDLGSIDWDDDLDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URD3</accession>
    <name>A0AAD8URD3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative glutathione-dependent formaldehyde-activating enzyme</fullName>
            <ecNumber evidence="5">4.4.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">S-(hydroxymethyl)glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_615969</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-(hydroxymethyl)glutathione = glutathione + formaldehyde</text>
            <dbReference type="Rhea" id="RHEA:22488"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="4.4.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">One-carbon metabolism; formaldehyde degradation; formate from formaldehyde (glutathione route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.22" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366524.1">
        <property type="nucleotide sequence ID" value="XM_060507939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URD3"/>
    <dbReference type="GeneID" id="85391838"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051907">
        <property type="term" value="F:S-(hydroxymethyl)glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00723">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014185">
        <property type="entry name" value="Formald_GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02820">
        <property type="entry name" value="formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003829">
        <property type="entry name" value="PRK05417.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF40">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033318">
        <property type="entry name" value="Formald_GSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="6">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>structural</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="191" mass="20699" checksum="A34515662C6FB36D" modified="2024-05-29" version="1">MAPSLHPLIDNGLTKGDPNFAGGKLRCHCKSNPVEVTLGGNVAHNHACGCSKCWKPAGALFSVVGVISRDQVKVTANESKLHVVDDSAVILRNACKECGVHLYGRIEKAHPFKGLDFVHAELSDEKGWQEPQFAAFVSSIIEQGFHPNGIDEVRNKFKSVGLETYDALSPPLMDLIATWTAQQSGRLPTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USJ5</accession>
    <name>A0AAD8USJ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_607847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368773.1">
        <property type="nucleotide sequence ID" value="XM_060507454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USJ5"/>
    <dbReference type="GeneID" id="85391353"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060870" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17111" checksum="0E8329621E1CA926" modified="2024-05-29" version="1">MMSRNPACSRPVGPLSGLLSALLVIIVQSTSISSPLGSSMRPDLALVENTTRVRYFLWSCDSASHRSRTQRKELAEERRLQREKNSQRRWTALAAHHLRLPATEDGEFLRQTRKVPNTSHSLPFCAHVHALEHSGLSTVYRPESCKDDHWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USV4</accession>
    <name>A0AAD8USV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_610607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368252.1">
        <property type="nucleotide sequence ID" value="XM_060507602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USV4"/>
    <dbReference type="GeneID" id="85391501"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="67" mass="7833" checksum="EA75DD9375F30D37" modified="2024-05-29" version="1">MHDPRTMLATYMLACTSIALSHLHSVRRTSCTNQHRTPIQTLELIPEVARIVQRFLHLGRVRRNRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTQ9</accession>
    <name>A0AAD8UTQ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline monooxygenase, chloroplastic</fullName>
            <ecNumber evidence="5">1.14.15.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_609916</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the first step of the osmoprotectant glycine betaine synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>choline + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = betaine aldehyde hydrate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:17769"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15870"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.14.15.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (monooxygenase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the choline monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.7" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368385.1">
        <property type="nucleotide sequence ID" value="XM_060507564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTQ9"/>
    <dbReference type="GeneID" id="85391463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019133">
        <property type="term" value="F:choline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00680">
        <property type="entry name" value="RHO_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03469">
        <property type="entry name" value="Rieske_RO_Alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756:SF5">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="47"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1728330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="409" mass="47100" checksum="1DEED1574AF28195" modified="2024-05-29" version="1">MSWFGLSKPSAAAEPDEPKAVRALPAIWYRSPAMYELERRAIFSKRWMLVSHKARFVEAGDFVQVTEAGFNFFLVKDRKGEIRGHHNICRHRAYPLVEKDSGHMSVLACNYHAWSYGFDGKLAKAPKYQELPSFDKSKNSLFKVHVHVDQLGFVWVNLDGAEKPSVPWEEFFAEVDTQPRLEGFNLDNYHFDHTWEMLGDYNWKTLADNYNECYHCQTGHPAVAATTDLTRYWVETQGNWIQHWNVDKETVPGLGIHSCYLYPNASMTVTPDFMYIQRCVPVSSTQSKMEYEVYRHNTATDEAFNFISDFFKQVLREDKDLCNGAQKNLNAGVFMNGELHPRVEKGPLFFQEITRNLVMRHKEREDKEGGEIWPATPKHDVSDKTGEDVSFCRSLDCGAGQGQIEGLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUE2</accession>
    <name>A0AAD8UUE2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_611362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367934.1">
        <property type="nucleotide sequence ID" value="XM_060507654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUE2"/>
    <dbReference type="GeneID" id="85391553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052961">
        <property type="entry name" value="Oxido-Kinase-like_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020:SF41">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23020">
        <property type="entry name" value="UNCHARACTERIZED NUCLEAR HORMONE RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="460" mass="51729" checksum="F3D6CD511A357829" modified="2024-05-29" version="1">MEVALTEPHQLSSNFTHLIAQAPFAGFSIANAQLVLATAAFSVTMASLKQPRHVAEIMLSWLGLELFSLTELQTLWAGYGHICALTAKLADTNGAANLDQKPLPIRPEEDGTYRLIIKLISPPRAKGTDEGHLRKMLSYEVEQYFYQEIAPRLSDDVAVAKCLASTLDMDNKPRKEELEGLTATIITDLRPDFPVAGEKRLVLNHEQVNAALDWLAKYHSSSWASLPDDLGQFVLPPLEEAKRREAGDGVTEPKMWLNGGYTYLATRRKEYGSLCRDDYSEWSSAFCDPVEGSSSSIAELVADFLTPSARPFETYIHGDVKSENLFTTKSGDKVAFFDFQYAGLGIGGCDLAKLFTCSVPVEMLTQHEDIPDELAMDKGERTILEKYRSTLMSQKPTGKGPDNYDWETFVRHWETALVDWCRFQASWGFWGNTEWLEARVRHILADQGWRDWLKKEATRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUL9</accession>
    <name>A0AAD8UUL9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_749370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368133.1">
        <property type="nucleotide sequence ID" value="XM_060513756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUL9"/>
    <dbReference type="GeneID" id="85397654"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088">
        <property type="entry name" value="YALI0F10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42088:SF1">
        <property type="entry name" value="YALI0F10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="685"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="757" mass="81743" checksum="197F0E1B4EBCD4A0" modified="2024-05-29" version="1">MASFNANGYVMASRIPIRDVQPVNNERSVAPLRIVSRIIGTRETCTGSASQCEKPVDPSTLTLPITLGVTIPIVGALCLLFYFHRRNVKRQKQEDATDPNRGLDFGLGETSSDKGGKGKRKSMMFREKGMGLDTKHRQLSMDMNLDSPYLLPPGLQSSRESLHSLARTLHSEADPYRPVAGYTGSDVGSIRSYKPDGASVYTKSTSRRGSAMTGRTTMTQNTLPPRQNSLPRPPPATADPFATPKSRSGSPALEIMTTNSPVVLSPTSPVIRSPLIAEPIIPKIETMPYPDDRNGGSLPQIPDVPEPAPVAQRGLPNNPRPSAKNPSIPEVQELDSTPAAAPVGLGLDDMNFPSQKNAAPSTLPTIVPEETNAYDRESYYDYDFEDRGRSQRRSVDMNDNRMSRALGVPGQDAKRLSVGFRPLPPDEVTESEDPEERANRIRSFYKEYFDPDNPHAGQAPPPMPQGPRGPPRGPPPGGPQYYEDYDPSYNGAPGGDAYFDPESNSFVMPYAQPVTRRAMTPPPSGSRFRGPPPPRAMHGSMGGRMASPGPGGRRPPPRAGSAMSSRLGPSRPGSDMSSQYTPRPGSSVSNRTAGGRPKPKVPPPADLTTMPNPSKLKDDSFSILNPLDFAPPETFSSRARGRSQSPAGERRPYAAPSIPVHSPLVSSFEEMPAMPSPHLLRKSGTFTGLDFAPPRKFKDGDNMSDAGSIRSNRSGISAVQQAALRSGAGRVSRLPGDTVFTATALDDQLKPQWGMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV37</accession>
    <name>A0AAD8UV37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Superoxide dismutase 1 copper chaperone</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Superoxide dismutase copper chaperone</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_717676</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CCS1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367654.1">
        <property type="nucleotide sequence ID" value="XM_060511972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV37"/>
    <dbReference type="GeneID" id="85395870"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000038">
        <property type="entry name" value="Superoxide dismutase 1 copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="6"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="27250" checksum="6443DAB70640AA67" modified="2024-05-29" version="1">MTVSYPFQTVFAVPMTCDSCVKDVSDSLYKLGGITKVEANLKDQLLSVEGTAAPSTIVDAIQATGRDAILRGSGGSNSAAVSILESFYHAEDASSKLNEQRDREVRGLARMVQVSPTTTLIDMTLRGVAPGSYRATIRQYGNLAEGASSTGPVWSEGSEDAAAAAAAKGFLGVFDVGKDGRGSAYLDKPFQIWEVIGHAMVVSRQDESAGALKNDPDTLVGVIARSAGVWDNDKTVCSCTGKTLWEERKDEVEKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVV6</accession>
    <name>A0AAD8UVV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable aspartic-type endopeptidase OPSB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Probable aspartic-type endopeptidase opsB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_169515</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368029.1">
        <property type="nucleotide sequence ID" value="XM_060501458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVV6"/>
    <dbReference type="GeneID" id="85385357"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000011">
        <property type="entry name" value="Aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000068">
        <property type="entry name" value="Aspartic-type endopeptidase (OpsB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 13 17" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042139765" description="Probable aspartic-type endopeptidase OPSB" evidence="15">
        <location>
            <begin position="19"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="16">
        <location>
            <begin position="68"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1727974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="467" mass="48931" checksum="E96EB62337BED089" modified="2024-05-29" version="1">MKSTTLIALAASLLPTEGLVLRKSESSAPRVVGLDLHRATIPYTRNKRDMLRKRGSVQATLDNLETLYFVNGSLGTPAQPMRLHLDTGSSDLWVNTASSALCKGQGTPCSVSGTYSANDSSTYNYVGSWFNISYVDGSGATGDYVTDKFTIGGSTLTDFQFGVGYTSSSAQGILGVGYKVNEVQVGRAGLASYDNLPAKMVSQGLIQSSAFSLWLNDLDASQGNILFGGVDTERFEGELKTVPIQKESGSYAEFLITLTKVTLGSKTLDENMALAVLLDSGSSLTYLPDDMTTTIYSMVGAVYQQEEGVAFIPCSTANSGSNMTFTFSGQPITVPIDELVLDLVAITGKRTSFSNGVEACLFGIAPAGDGTNVLGDTFLRSAYVVYDIDNNEVSLAQTKFNATSTNVLEIGKGSSAVPSAVAVASPVSATDGIVRGGKNAAPSLAPLAASIFAGSVAFATGFSLYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVZ2</accession>
    <name>A0AAD8UVZ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Polyadenylation factor subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_572801</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367340.1">
        <property type="nucleotide sequence ID" value="XM_060504552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVZ2"/>
    <dbReference type="GeneID" id="85388451"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001039">
        <property type="entry name" value="Polyadenylation factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:002008">
        <property type="entry name" value="Polyadenylation factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="133"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="175"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="446"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="516"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="520"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="600" mass="65122" checksum="D49D4E4C688439B3" modified="2024-05-29" version="1">MRHRSPLDGDAYTGEVERPSASFIVDFIPPAARRTDPGDTIPVKHLHSSLNKIKHPVNVVRWTPEGRRLLTASSSGEFTLWNGTGFNFETIMQAHDSAIRALAYSHNDDWLISADHDGSVKYWQPNFNNLQSIAAHNDPVRDLAFSPNDSKFVTACDDSTLKIFDFAGGVEESTLKGHGWDAKSCDWHPTKGLLVSGSKDHLVKLWDPRTGRCLTTLHGHKNTITKTLFEKVQGDCLATSARDQTARVFDLRMMRDICLLKGHEKDISTIAWHPVHSNLLSTGGHDGSLYHYILDEPNTPAGHANSVAPYDSSDPSTTPAQTIYPAHKVPFAHDFAIWSLDWHPLGHILASGSNDRITRFWSRKRPGDADVFQDRYHVGEAAAEANGTWDRRGGRRQRQEEEEMEMEDEMDGLVDQKMPLKQPMVPGFPGLPGLPGLPGLPGLSMPQNGGAGGPVPPPPMIPGVGGAGGAPPPPLPFPLPGLNGAPPPPMIPGLPGGIDPSNPADLAKIAEMIQKAGGTLPPPPPGGFAPPPGMVPPPNFVPPPGFPPMPMSMPPPPGANNNNHRDRDDHGGRGGRRAPLPSQEESLKQEQRRGNYTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA34</accession>
    <name>A0AAD8XA34_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">E3 ubiquitin-protein ligase HERC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_589312</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359752.1">
        <property type="nucleotide sequence ID" value="XM_060506223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA34"/>
    <dbReference type="GeneID" id="85390122"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF187">
        <property type="entry name" value="EF HAND DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="136"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="492"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="756"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="778"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="917" mass="104116" checksum="BB50BA6BF2D395BC" modified="2024-05-29" version="1">MWLPLPSTDTLTRPRIAVVLFSAVAAASLGYYTYQANRDQYDEIPGPGLHRSNAVRRNHRRSRRNSLSSEGSHGDENVDVDARPANDADTIVDGGTVDEWWNDPNSMQPQARAGHNIVSLLFRVSEDNARRNACVHRGCACNACGMVPIRGVRYRCANCADFDLCETCESQGVHIKTHIFYKIKVPAPPFGPRQMQPVWYTGDPDTQIRNLSKGLMARLSRETGFERPEIEAFWEQFTYMANTEWREDPDELALAMDKKTFERCLVPSGGSRHATPNLIHDRMFSFYDTNNDDLIGFTEFLHGLAYRKRKDKLRKIFEGYDIDGDGFVNRRDFLRMFRAYYVLYKQMHRDILDGLDDQLMGSTEAQQLVTSRQPLSSLFGREGRVPRADGNNRSEGKIFHPDGDVELEPGRRGVVSDNRVDTSGREDVLTRLFAPYIGSPWSLQMRSPDSEPSTPYWDALLNPPTTIDDLPALLTGQRRERNGIEFDFEIELGSSDGDEGGNNNSDAENRSQPGDDPAQVNGTTNHNQRVDPDQFTNAMPTESQLRAQVINHKRQMAPDIERKRRQAARKQLHDRWKRRQFYLDEEEGGFAPDGWQSDEDVLVNLNGVAESSKAAQQQTLPPRSRSSSKVRFAEDMDDYETRSNPSTSSRSVPERWGGMEIPNEERDAGREILYQVTQQAFNELLDAIFKDKENLAVKAAATKAKRDKNRPLFEHLTVAEPKRKVVEPRQPRKALDEDKPVAERTLEELLMTSGYRIGETGETENAPISEERQRVEEVIDSDEDDIEVNEDDEEDASTVEEVEYRDPTMPQFRPNSEADEPMSPGSTPPTSDDSSFSTKGLKSPVQGKTSKSSKESKTIPHFTLLEWKRLDLAEKEAADRGGWGKLSFDEFEEIYKSQENAGNRLDYLGSWVDFCIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAA0</accession>
    <name>A0AAD8XAA0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gelsolin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_591208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358901.1">
        <property type="nucleotide sequence ID" value="XM_060506410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAA0"/>
    <dbReference type="GeneID" id="85390309"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11290">
        <property type="entry name" value="gelsolin_S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF130">
        <property type="entry name" value="SEVERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00597">
        <property type="entry name" value="GELSOLIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="68"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="193"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="319"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="44350" checksum="DA2F77878E40BC63" modified="2024-05-29" version="1">MAPNQGLVHPTEYDIKDSNVELIGTDIDHQVKYNSASTEPAWNEGEVGRAAGLHVWRIEEFEVKPWPKEKYGQFMDGDSYIVLNSYKVGSKDDAEKLGHDIFFWLGAHTSQDEAGTAAYKTVELDEFLHGAATQHRELQSAPSDEFLELFPRIQIRSGGVKSGFRHVEDEERKEEILTLLRIFKNPSVGANGVVVHEVEPTWQSLDEDDVFVLDTGDKIWQWQGKSCSPMEKAKAAQVVNDMTLAKHIDVEVLAQEESRSRVIVTLLGGSDDTPQSGFHCPRPVRSASKAHAGERPQKLFRLSDASGELRFDLVKDGSKAALSDFEEQDVFLLDDAGRAVWVWEGQGASRGEKANWLRVAQAYVRQLQGGPEADEAHLTPVAKVTQGNESRAFLKAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAG1</accession>
    <name>A0AAD8XAG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_655648</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360489.1">
        <property type="nucleotide sequence ID" value="XM_060510814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAG1"/>
    <dbReference type="GeneID" id="85394713"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF8">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="56681" checksum="8349AFC30455E7DD" modified="2024-05-29" version="1">MIRSFGVEQNDVAKWAGITSAVFSLSQSVTAVPWGRASDRFGRKPTIIVGLLSTMFFFCVWGVSTSLPMAITVRAILGSGNGNVGIIRTMVAEMVPEKELQPRAFSIMPLIWSVGSIFGPAFGGFFARPADRFPAVFGDSWFFKAYPFALPNFIAAVFFFISVTTATLFLKETLESKRHKPDWGLLMGERITRSFRRSRHHHHHHARARRTSFVDGEATAPLVPHKTPPTHPVEDNKALEAPSMKEVFTAQTSINLLCYTFLALHSVAFDQVLPVFLNYPKQEHTPENTNLPFQFSGGFGLDSGRIGTIFTIYGITCGVIQFFVFPPLCNYFGVLRCFRACAVTFPIVYILAPYVVLFESTAGRYTALLIVMFVKACAVIIGFPCMTILLTNSASSLRILGTLNGFATMFSGFGRAFGPAVAGAAFSWGVARGYVITAYWFLALTAIIGAIPIYMLVDYDALTQTPDTSDDEDESVSDEGYASEGSAVASGSGQSASNETAPLLSAKNGAPGYDSVSPTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAG8</accession>
    <name>A0AAD8XAG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_682852</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359126.1">
        <property type="nucleotide sequence ID" value="XM_060511225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAG8"/>
    <dbReference type="GeneID" id="85395124"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF9">
        <property type="entry name" value="TAH-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="703" mass="77011" checksum="BAB919AE89960745" modified="2024-05-29" version="1">MPRPKVPESQRQRAAEACRFCREAKKKCSGTAPCNQCVRRGLEPDCRMTYLPRGSRTKRPSHGSITVSTTASGSSKPRPQRHNEIDTEPPPNPFPMSPSVSQQGSEKPCVDAHQSPMTPPRESHTGEHTRLESSLLANPSRLLRSAHGEQVFVGGAAAISFLQTVRKVVVRQIGPSPFSHNDGMETMLEAESPEARRSISSDQAVDLGNQQRLDYLKCYYTITEGLINILDSDDQRDLMCLNDSISIGGTSPFDENTSADKAAWPSKNSSHLSDAIRDMVMAIGAQCSSAPEAQDHSFTFFRKAQRQAFSGLLEDPDLDMVRLFLLMAFYMLGNCRRNTAYMYISIAVRAALALGLHSQTMYTCEPKSHQCGLLKVWISVRILDKLVSSLLGRPAATAGTDARPLIGDLAPDCNYGSKYLVATCEIVEIINNINNTLYHGKDITVPVVEQLLVNIDSWKRDLLMPLEGPEQPEVLADSVEANRMAVAKIHVSCLYYFAVTLATRPIFISSLNSQAGNKIHHPPLAAACIEAAVYLAQTCADALNTGLLERSMCILKALVFSAGLILGVECFAKVSIDLETDRAFQGAMEVLKFLAGQSPQAAHYLEILTSLATAITERRSKWNNAGGSRYVSRLFSLESLGSVSAGNQEGYTEDEPSWAPTRAVTEPGSFDVWPGADGGLLNWSEFQFDDGDLHIDWQSLSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC15</accession>
    <name>A0AAD8XC15_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_544138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358420.1">
        <property type="nucleotide sequence ID" value="XM_060503432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC15"/>
    <dbReference type="GeneID" id="85387331"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042178803" description="Cell wall protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21056" checksum="AA0DD9402D655F10" modified="2024-05-29" version="1" fragment="single">MVTMRLTLALFAQAAIITAAPLQPIRIIQIEERAAGDLDTIERALAPVSESLANVDAAVLSLDGGPVTANNLLIFSQQAQVATDQATVDIQSAGDLGAFRAARLRRTTDALIDQTTVTVNDLVSRKPVLDNLGVSGVALESLQRQKISSMALTAALEEKVPRVGQRIAAEGRAQIESVMDQAIAIYSEPAVAAVPAVAPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD35</accession>
    <name>A0AAD8XD35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_702510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363354.1">
        <property type="nucleotide sequence ID" value="XM_060511460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD35"/>
    <dbReference type="GeneID" id="85395358"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF60">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="146"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="586" mass="65122" checksum="92384535A68C5541" modified="2024-05-29" version="1">MSDSKPHAYYFVPRKPVSADSETGYSLQRTLTRSRSSLWRGWSPGLPSFTEYERTAYKFPWLQNPVEESGSRHPGIILETSAHDDRSHLLSHDDTQAGPSADVPLEEKPAQEIKPDDPEDPDLVTWSGPDDPMNPKNWARHKKWTATILVSCFTFISPVSSTMLAPALDTLADDFDVESDIETYLLMSIFLLAYAVGPFVLAPLSEMYGRVVVLQSANMFYLIFNTVCGFSASKEQMLAFRFLSGLGGSAPQALGGGVLSDCWRAEERGTATAIYSLAPFLGPAVGPIAAGYLTQYLSWRWIFWTVSIADAVVQILAFLFLFETYAPKILAAKAKILRKKTGNANLRTEFDHPDRTFAQTLRKNLIRPFRMLFTQPALQITAVYRAYLYGLMYLVLASFPYVWSEQYDMEPGPASLNYISLGVGFVIGLQISGPLIDKVYRKLKAQNNDTGRPEFRIPLMFPTAIITPVGLLLYGIAAHFEVHWIVPNIGAAILAAGLIVSFQCVQTYVIDSYERYTASAAGAAAFVRTMAGFSFPLFAPRLYDVLGIAWGNVLLAGIVFVMGLIVPFVMWRWGAWLRSKSQYCAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XER1</accession>
    <name>A0AAD8XER1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_655234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360970.1">
        <property type="nucleotide sequence ID" value="XM_060510788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XER1"/>
    <dbReference type="GeneID" id="85394687"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="30318" checksum="5A6FEB532F5368E5" modified="2024-05-29" version="1">MILGQVIKEYKGMDRDPTKIHKEVRKRLKDGGYAIPLFSEFMLRLEELRAPTSGSIISNNVNPWCTSPMHKSYTITRDTREHKNHPKRLEQIPYLKRSLIAVWRHEEKAKRRAQRLGTDRDQEHEGSNSDLAVGILRERLKAAEAMCTRLAQEKDSMVSKIDAAEARSSRDGMRIAELEAAEAQGASGGALARIAELEAEIQRLKDDSSTRGSTVHSRSFGDDGFGDGFDFSDTGFGGGDTGHSSEDETPGNPTSHIGRTSELKTTPSLKRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEY4</accession>
    <name>A0AAD8XEY4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">X-Pro dipeptidyl-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362303.1">
        <property type="nucleotide sequence ID" value="XM_060512901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEY4"/>
    <dbReference type="GeneID" id="85396799"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="600" mass="69006" checksum="4F00542A58A48C17" modified="2024-05-29" version="1">MATHRLATRSHQGGVSDGDWVDVSDSREQHAATTISESMPERIIRVTTDEKNLNKFYNIKFSATRSHRLERYYNEELDSLFKAPFDTYSQEDKVDFLLLRNYLRRNLRVLLLDRERDELVKPVLPFIQPLIEICEARQSMVPVDSKKTAMILNETAKEIIATTKAIKTNGIKANDSTFSRAMSTIDQIRGHVDETYGFYAPYDPLFPFWCDAPKKELDEALTGIKTAIDTKLVQKNGSGSIRAAVEPIGRSGLITELEAEMIPYTPEELLKLAQERYDWCEKEMKKASRSIKVGSVRPERSHGSVSGLEAPDAGFGDDWKAAQKYVKNSYVEPGQQPEMVRQLAYEGMAFVKKHDLVTVPEIAGETWRMFMIDAERQKESPFFLGGSSFWVSYPTAAMDHDLKMMVMRGNNPHFSRATAFHELIPGHRLQLFMGKRHHPYRELFSTPFFVEGWAMYWEFVFWNRGDFFVSPEDKIGTLFWRMHRCARIIFSLKYHLGEMTPQECVDLLVDWVGHERSNAEGEVTRSFGGDYSPLYQAGYMLGALQMHGLREEVLTKGLMGEKELHDKILRANTMPIELLRALLLDQPLSPDTEAQWRFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF04</accession>
    <name>A0AAD8XF04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_619941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365409.1">
        <property type="nucleotide sequence ID" value="XM_060508164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF04"/>
    <dbReference type="GeneID" id="85392063"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="11913" checksum="4D14BD91316EC5FF" modified="2024-05-29" version="1">MTWSPRHCIPRIFTPTFLLTSSQTAEEDSPLQAVAQPNPTTLLLVPLSLSLQSHPPLPPAVVRTSAAWIFTDEPQPGEPRCTSLTGGLMADEKQTALASNPHHEHANRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF13</accession>
    <name>A0AAD8XF13_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364867.1">
        <property type="nucleotide sequence ID" value="XM_060508261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF13"/>
    <dbReference type="GeneID" id="85392160"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="41"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16062" checksum="E8CA0F1ABC4D2D73" modified="2024-05-29" version="1">MSMSARILRSSFVPAVRRPFVTTRLVSSPFTRCRTMATKEFLCILPDKPDALARRLEVRPTHLENAQGHKSNGKVAVGGAMFEKEHPVEGQTPGFKGSVMIYTVKDAEEAWELIRGDIYAKNDVWDLEKAQVIPFKSAIRESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF68</accession>
    <name>A0AAD8XF68_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit NOP10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nucleolar protein 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Nucleolar protein family A member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">snoRNP protein NOP10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_755317</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361345.1">
        <property type="nucleotide sequence ID" value="XM_060514592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF68"/>
    <dbReference type="GeneID" id="85398490"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.300:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1718845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="61" mass="7147" checksum="D8BF6F005A6F01D2" modified="2024-05-29" version="1">MHLMYTLDEAGSRVYTLKKVVDGKVTKSAHPARFSPDDKWSRQRVTLKRRFNLLLTQQKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFZ8</accession>
    <name>A0AAD8XFZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_718498</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366579.1">
        <property type="nucleotide sequence ID" value="XM_060512079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFZ8"/>
    <dbReference type="GeneID" id="85395977"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="26016" checksum="7D2D9046185C8F4A" modified="2024-05-29" version="1">MSLQDKVILITGGSKGIGKAIALDAAAQGAKIVVNYSSDSSAADEVVKTIGSDRAIAVRADGSKTAELQKLVDATVDKFGKIDVLIPNAAIMHMRTVENTTEEDFDQMFNTNVKGPYFLVQKALPHMSDGGRIIFLSTTVLASSSLPPPYLLYASTKGSIEQMTKYMAKDLAKKGINVNAIAPGPTGTDLFYKGKTEEMLKHITASSPYNRIGTPEEIASVAIFLSGKESSWVTGQIIRVNGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGG8</accession>
    <name>A0AAD8XGG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PXA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_651397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365426.1">
        <property type="nucleotide sequence ID" value="XM_060510450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGG8"/>
    <dbReference type="GeneID" id="85394349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000065">
        <property type="entry name" value="PX domain protein (AFU_orthologue AFUA_2G07450)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="4">
        <location>
            <begin position="177"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="746"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="746"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="797"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="812"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1101" mass="120368" checksum="513F3A9BCBAA0C68" modified="2024-05-29" version="1">MDSTPAEVHPPGGASPVADEKLPATETTTATTTTTPSTILPAAEEKTAIASAPSTTAAATPEAQKPGGNSEEEDDLVTRVLKFLSTATPETLGAIAVGLAASTYFILGKVGLVLIGAFGGIVAFISYEARHPEVSRAVRGEKGIDVLQRLALVKIAEPPKNDEEEEDRLIHGFDDFQPETREALTGLVDAVIRDYVKWWYNPILPTDSSFPLSCRRLLNSFLLSVSNHLYRKRPADSFLDFMTNASSMFIVFLSELSSAFTDQNNEPNSTAPEVISKYLEENPNSNLANLLNRSQQAAKFHNVADDLLGFLERSAYNCDPARVFLLEILAGVILEMSLQSCSSPEWINAWIVYLLEAGEPDFSQAIDVGMQTGPEAATASAASAVNNANAFIDIDGNVGNIALTKGNRNSLDTERERRKGSLVSHKKQLSKADEEMEEAMEEMKRMNALIAEEEAKRVKTRQSVDSATKPTVQTAEGNIVSSPGELSPRSLSSAEKPSTNGSSGSNESDVSKRESMHSPVTDSSSQKSSPKQPSSKHASSGSASQFLNFDQIVPPAKEEPEVPEESSRKLPLTLHNATITLYEDGNDNNRIRSKPNWDYMVQIEPSSSHYPGWMIVRQYSDFETLHEILRRIANISGVTAFTEQHAELPNWKSHTRASLRGELERYVKDACWYKSLAESEGMKRFLEKDSGHGHSNSKSGLPWDTVGKNMLDVLTMGPKGAMEGGKAVFGGVTGMFNNIGLGPRKNTASSLSEIQTSNHRWSTGTPPRMDSTTSLNAALTSPTTGVGPRKGRDSLDSQRSSIVSTQPGKIAPMERRPSFDPRGDTEADSLKPRSDRWERNTPSATGSREHSRASSLAPLQSPALRSPSSTSLDVMNLQYLPPPPDEMPEDYQSPTQGDMQAKMDEVISPRNSMGALSPGLPQTQPKKKEAKPARQYSPLQEQETNVAVELVFAIINEMYTLSSAWNIRRTLLAAAKSFLLRPGNPSLIAIQKMMQESVIDANTKDEGLAYHLRKLRENTMPTDEERATWPAEMTEEEKEKLRIKARNLLIKRGVPAALTGVMGQAATTDALGRIFDCLQIQEVARGFMFGMMLQAVRVVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHW4</accession>
    <name>A0AAD8XHW4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flavin monooxygenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_620437</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365363.1">
        <property type="nucleotide sequence ID" value="XM_060508192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHW4"/>
    <dbReference type="GeneID" id="85392091"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="64975" checksum="0356E6F01929018E" modified="2024-05-29" version="1">MTEKRPSLVAVVSLYLYTSACQKSYREHASLLSQTNSISRNCLSSINSKKTMASPTVAVVGLGALGLVALKNLREEGFEAVGLERNDYVGGLWHFDEGEKLTVMRSTLSNGSKQRGCFTDFPFPKGSPDYIPAAGIDKYLQDYAKHFGLMEHTRLRTSFHGATFVEKTQQWRLSLSSPEEPEPHFEYFDKVVFAMGADQKPSRPKIEGMEKFKGFVEHSMTFKNPEVLAGKRVMVLGFGNTAADMATELAPLASQVYLSHRHGAVIVPRWVKGKPVDHVRTYRKYVILNLMNRYTPGLWEKTMNSVISKLEHEIFDLKPEWGFDPAPSITNQRPLVNDELIPCLENGSIISTPGIARVIDEKTVETTDGKRYEVDAILLCTGFTVDYSVVGPHADPCRATTTDWEKSDGYTGRPLPRLYQNIFSLDHPRSLAFIGHLSFMNPAFFMFDLATMAVAQLWKGASAFPSPAEMEKQVNDQHAWVLQLSKKGPVTPSIVKASEWMEWVDKVIGTGLPEHLGYNLNGWSFWIRDRQFCNMLMDGLLSPHAYRLFPGKRKAWPGAREAIMAMNVDREARFGPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHW9</accession>
    <name>A0AAD8XHW9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RAD52 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_719230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365378.1">
        <property type="nucleotide sequence ID" value="XM_060512156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHW9"/>
    <dbReference type="GeneID" id="85396054"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.80:FF:000001">
        <property type="entry name" value="DNA repair protein RAD52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004585">
        <property type="entry name" value="DNA_recomb/repair_Rad52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00607">
        <property type="entry name" value="rad52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="234"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="272"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00077224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="55423" checksum="E3D2A38CB6853914" modified="2024-05-29" version="1">MPAPGDQHSIVVNPFEEPQKRMSEYTAQEIATLQSRLEKQLGPEYLSSRSGPSGQKVHYITAEKCIALANEVFGFNGWSSSIQNIQVDFVDEHPQTMRISLGLSVIIRVTLRDGTFHEDIGYGHIENCKGKAAAFEKAKKEGTTDALKRALRNFGNVLGNCIYDKDYLARVIKMKVEPKKFHEDDLHRQRDFVVKRGEEKAPVATAAPPAPPVKLEATESLEDLMDEDFDDVDFAISEGDHPDEVTLPPTTNGNSNSRAASVAPAPVPQHIQAPSRQMGRSTSAGNLGNNGNQRPPQTPNQAQSRPGPPTGYGNRPQPPNQPRAPTNPSGPSAPLAPPANANLTTPGQAGNVAAEPVGFFSARAVQQIPESALQGNNADAPMLLPAGQQAFNPKAESPSIRKTPGIDHSSSKPLSRSGQHVPPTPSQQPSTSGFTPVRPGNAGPGGGAGMPHPQFSQTRRIGAPGGAGSPLANRNSYRPPTMKRPLQQDGAGRPALADVSNNGTSGNPPGAPGADPKRQKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIN4</accession>
    <name>A0AAD8XIN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_717380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368051.1">
        <property type="nucleotide sequence ID" value="XM_060511943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIN4"/>
    <dbReference type="GeneID" id="85395841"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042257767" evidence="1">
        <location>
            <begin position="21"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="209" mass="23104" checksum="91AF93523D430CBA" modified="2024-05-29" version="1">MQSYHFLLTALAATTIGATCLPSYPGCPAFPSSMITFSAGFEQPQPPLIKPEYQASFVQHKWNANLSHITTGYIDNSPSGAFVRVGEAYEGQISWSLFDYSNVSESGLVDNTMTTYGPNSTTPSVWRGYVNSNFPIFQSNILVEAGAVYEGLVQRNFIPSPVAAWSIMYQDAIPVTVYVNECDVVVGYDYFAPDLRTRVIMEFFNILAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR3</accession>
    <name>A0AAD8XIR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_152532</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368231.1">
        <property type="nucleotide sequence ID" value="XM_060501339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIR3"/>
    <dbReference type="GeneID" id="85385238"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000085">
        <property type="entry name" value="Putative ras-related protein rab-11a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="212" mass="23174" checksum="A4160B837AF41D25" modified="2024-05-29" version="1">MANDEYDFLFKVVLIGDSGVGKSNLLSRFTRNEFNLDSKSTIGVEFATRSIQVDSKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDISKHQTYENVTRWLKELRDHADANIVIMLVGNKSDLRHLRAVPTEEAKAFASENHLSFIETSALDASNVELAFQNILTEIYRIVSSKALDSGDGPQASIGAGAGISLSTPADNSAEKSGKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIV4</accession>
    <name>A0AAD8XIV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_621090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365140.1">
        <property type="nucleotide sequence ID" value="XM_060508233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIV4"/>
    <dbReference type="GeneID" id="85392132"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="30185" checksum="05016E7AD27C12B5" modified="2024-05-29" version="1">MPAKDGSIILDTTETINNLKIRFRISGPAGEFTTASKVPGGGKTTGAKGNLGLHVLLHGDSGSSFFEMPNQGVKNNLAGVTVLSPDRNLHWGGGSGFNRTDGVAHAQAVNDLVFQTLPKYMAFNSSNVFFSGISGGSLLLSGYFMPAHMGNFAGNGVMLGCGAMEPRVEVSQSSRDALMKTRLHYQSTQKELQHLQGSISATMKAYEKVVKDKGMKTEAINKLQTANNTPVGGHCQFDEKGFDSGIQLIADNYAAIMQGGNGEVPGIGNVLKGVSGQELKFSDGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJJ5</accession>
    <name>A0AAD8XJJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sucrose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_573991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366775.1">
        <property type="nucleotide sequence ID" value="XM_060504668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJJ5"/>
    <dbReference type="GeneID" id="85388567"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF76">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="60289" checksum="E19BBB4E98AAA1D2" modified="2024-05-29" version="1">MSSWAGQPSIRGSSEAMRMVLLTFNTLGITFTWGIEMTYCTPYLLNLGLTKSNTSLVWIAGPLSGLVVQPIVGAIADESKSKWGRRRPFIVIGSIIVAISLLTLGFTKEIVEMFVSDKETARIFTIILAVVAIYFVDFAINAVMSCARSLIVDTLPIEKQQTGAAWSSRMSAIGHMLGYGAGAIDLVGIFGKTMGDSQFKQLTLIATFLMLFSSGVTCWAVTERVLVSTRHDPRKATGRFKVFRQIWSTLLHLPPRIQAICWAQFWSWIGWFPFLFYSTTWVGETYFRYDAPVEGKDSKDALGDIGRIGSLALVIYSTITFIGAWLLPMVVKSPDDDNFTARPPQAIAPFLERFNKNKPDLMTAWICGHLMFAAAMFLAPFAQSFRFATFLVAFCGLSWTIAMWAPTTFLGVEVNKLSGAREGGSGTAAYRRLSNDSNIELPTLGQDQPLHLEHGPDEGGQQTTSSTGELSGIYFGILNIYTTLPQFIGTFISTIVFTILEPGKSPELSDAPEHEQHNTDGPNAIAVCLFIGAICAVVAAFATRKLKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJT3</accession>
    <name>A0AAD8XJT3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-xylanase</fullName>
            <ecNumber evidence="11">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_572157</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367585.1">
        <property type="nucleotide sequence ID" value="XM_060504477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJT3"/>
    <dbReference type="GeneID" id="85388376"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF35">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 11 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 12" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289418" description="Beta-xylanase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="14">
        <location>
            <begin position="17"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="372"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1727530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="408" mass="43072" checksum="B6011FC2756368A4" modified="2024-05-29" version="1">MRFSTITAAGLLASGVSANLHELAVAAGKKYFGTATDNSELTDTAYVEILKDAKMFGQVTPGNGQKWQFTEKSQGVFSYTSGDEIADFAKTNSKLLRCHTLVWHSQLPTWVSSGTWTKEQLTSIIDTHISNVAGHYKGQCYAWDVVNEALNEDGTYRDSVFYKVLGTDFIPIAFKAAAAADADAKLYYNDYNIELAGNKQKEVLNIIKNIKDSGARIDGLGLQAHLIVGSAGSRSALSAVLQSYVDAGVTEVAYTELDIRHKAIPADTAAQEQQATDYVSVVGACLDIAECVGVTIWDYTDKYSWIPSVFPGTGEALPWDKDLKPKPAYTSISSLLAAAGKGGAAPATSAPAVATSAAAAAVSSAPAAAATGGAARWAQCGGNGFTGSTTCQSGLTCQKQNDYYSQCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKJ2</accession>
    <name>A0AAD8XKJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="14">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_65181</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369113.1">
        <property type="nucleotide sequence ID" value="XM_060510481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKJ2"/>
    <dbReference type="GeneID" id="85394380"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000015">
        <property type="entry name" value="GPI ethanolamine phosphate transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017852">
        <property type="entry name" value="GPI_EtnP_transferase_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04987">
        <property type="entry name" value="PigN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="560"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="589"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="614"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="761"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="858"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="893"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="924"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 1 C-terminal" evidence="16">
        <location>
            <begin position="449"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="957"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="961"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1729058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="992" mass="109277" checksum="7B5B8617E354FCB7" modified="2024-05-29" version="1">MAVSSRAGFLAVAVVFHLVYIYSIFDIYFVSPIVSGMKLVQVERPENSKAPADRLVLFVGDGLRADKAFQSFPDPYPESEDDLTPRPLAPFLRSRVLEYGTFGVSHTRVPTESRPGHVALIAGLYEDVSAVATGWKLNPVNFDSVFNRSRHTWSWGSPDILPMFEQGAVPGRVDSYTYGHEFEDFSQDALQLDFWVFDHVKELFADAAKNETLDAALRQDKVVFFLHLLGLDTNGHSYRPYSKEYLHNIKVVDQGVKEITEMIENFYADDRTAFVFTADHGMSDWGSHGDGHPNNTRTPLITWGSGIAPPVLSSDSVAPGHDEYSSDWHLDEIKRHDVAQADIAALMAYLIGVEFPANSVGELPLSYVSSSIEEKAQAALINAREILEMYRVKEEQKKATELRYRPFQPLSDAGLAPERRVAAIQRLVDAGNYEEAIEESAALMKIALEGLRYLQTYDWLFLRTLITIGYLGWMAFALTIVVDLHVLRGSQLPSRTTLGTTAFSSVLAVLYASFIISKSPITYYAYGFFPVVFWEEVWARRSSLIEGRKVLFGHIKTGASVFSFLLNLVAYIGIIVSLALGYIHREVLTVIYVLAAFWPMTYGLRFLQLNSLLSVVWFFSCLVMSVFTLLPAMKSEDIPLIVAGGIVMTAIGLAYLIWEDRLLAKPALPISRALTGVQTLQIGLILLAIVVTRSSAISLQAKTGLPRGNQVVGWIVLVVSLLMPLAQRLQPNSHYKHSLMTMFLTCAPTFVILTISYEGVFYVAFSALLVAWVGLEHRVFVFSKGTDEDRRSSSKETASKPKEVSTSRFRALTLADARVCLFFFVLLQSAFFSTGNVASVSSFSLDSVYRLIPIFDPFSQGALLVVKLMIPFALISANLGILNVRLGVAPSSLFMVVMAISDVLTLYFFWVVKDEGSWLEIGSTISHFVIASLLCVFVALLEGVSALFISGIEVEGSEPKAGQNGTAAAASTSAGGTIANGNGKTSGAGTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKP7</accession>
    <name>A0AAD8XKP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369205.1">
        <property type="nucleotide sequence ID" value="XM_060510154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKP7"/>
    <dbReference type="GeneID" id="85394053"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="29174" checksum="8251F32656928752" modified="2024-05-29" version="1">MGDRDTFSAQTYGVGLGLPEGEQAEQGVAGRGMQTGTDVPKPTGGTAKDRPAGSSTRFSVFPLPHAWHLNHFHWAHTLVDPGQLKLSQIFTAHAKGKVQSLMGHAPGLNLFGTKVHVRASHPTTSWYRTLCKLNLHRVSIRQRESIRQGSASEKGILVPQYNRKISSSNQISFNPYRPMVRTCNGTPQGVLSGRSRIFCYHLRYGSKEKVLPSPLTFPFPPDPIGICTRMSSPATIQMTGTRTCFALLCLTLYPSTKVGATVDHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL06</accession>
    <name>A0AAD8XL06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase I-specific transcription initiation factor RRN3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369402.1">
        <property type="nucleotide sequence ID" value="XM_060504106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL06"/>
    <dbReference type="GeneID" id="85388005"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001042">
        <property type="term" value="F:RNA polymerase I core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007991">
        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="686" mass="78263" checksum="B0385DF78FEF3CC8" modified="2024-05-29" version="1">MRPFTPISRHRSGPPPRTATPIKSILRQTVLGRRKADEIEFDDPPPSPTKRRKVLINEMNNRVFEFGSRSMDEVNSEVRKALEEHLMGEDEDYDMLKEIFANDKQRYLPPVAGEDEDTLKPQELKGYVLALTSCVPLLKNKACNGLVKTVLQVSWLGRDEDFFKVYIQFLAALVSAQGSYLTHVLSMIVEKFSHSRQSEWGVADFPTVSRTTMRERLHTGLQYILQMFPAATPVLRGLLETKFPFDDDPKKMFVAYVNNLLRLKEYAGDLDLEIVDVLLSRLVKIDVQMQTDLDDLDDDLTASVAYALSKSLDTGSWEGDEDASDEDSDDESVDSDDSDFDDNEEKIRVVKGNVEKLDAILDTLFAHYTPLFENPDSDQAWERYALLVQSFGKIVLPTYKSRHTQFLLFHFGQMSARLRDTFVGSLMHIFGSQNRPSFVRQAAATYLAGFMARGAHVPSDLVRTVFALLLKQMQIYRLKHDADARGPDLRRHQIYYAQVQAALYMFCFRWRDLNVSTPEFVDPEDPASYLGHELEWMQGMREELSASVYCKMNPLKICAPAIVEEFATLSHKLGLMYIFPRVEENKRIRLSQFVSDTYGTGGALRDTGSGAQDEEAYQLDPYFPFDPYQLPVSKRWVQNDYVHYQAIPGLNMTADSDSEDDDDDENIPETDVEEDTATASEDEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL90</accession>
    <name>A0AAD8XL90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_32425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369506.1">
        <property type="nucleotide sequence ID" value="XM_060502388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL90"/>
    <dbReference type="GeneID" id="85386287"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="28282" checksum="AA430B12D60C3C63" modified="2024-05-29" version="1">MPCRSLHLQEEKRRQQLMFGVTVASAPAARFLLSLSASGALFFTLLHYGVSVPHATPYSILYTQAAFIHTFSVFQKLRVTWWTDFDMVHSLLYMVHGRVNHPGFKRRPRPRLANSERQPICLRQGLEAVSVSHDSCFAMYYCPVSRSTISGFLPRRSVQATGPKSLVRDKQRTPNAIKPTPCRRQRLSSLGRVRPNLDHAAHNHIRTLSHCTYERTVRHPSVSVQSSTHFMARTALTSALYGKDPRNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH9</accession>
    <name>A0AAD8XLH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_34740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369584.1">
        <property type="nucleotide sequence ID" value="XM_060502495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH9"/>
    <dbReference type="GeneID" id="85386394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14723">
        <property type="entry name" value="ZIP_Ppr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000006">
        <property type="entry name" value="Positive regulator of purine utilization"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="785"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="832"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="971"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="790"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="971"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="994"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1003" mass="109991" checksum="C8A2AE88960FCE53" modified="2024-05-29" version="1">MPAHSPPSPTIKPTKRPRQGSYDVDVSPPPSAGIDQSPSAAEQNDPMANAGAALTSAEKNGGGGGGKAGQSSNFRNVSACNRCRLRKNRCDQKLPSCASCAKAGVACVGYDPITKKEIPRSYVFYLETRVEQLEALLANQNIPFPPAENLELCSRPGAEIARSTTEVPPSARSESNDGPGPAKNNIHRPDLEKAKKAESGGTGMLDIVSPSKPRSLASASGVSFNRVVFAAVQYSVSDHNGTQDRIGGKGLPIGSGTSMRDSFFGLHTKPTIRPANFPDKDVGMRLVTLYFEHANPQIPILHRGEFMQMFDQAYADPSGPKGARELYMLNMVFAIGCGVIVGEPVKSEGSGAGPRNPADANKFGQAQPEEYHASAIVHLEACLGNSGGGLEVLQAVLLLANFALLRPVPPGLWYIIGVAVRLAVDLGLHYEDGSDVEPAMRDLVKDENGEVNEARNAQSRERGRRLYIRDMRRRLWWCTYSLDRLVSTCVGRPFGISDQVITTEFPSLLDDQYIASTGFLEIPADSSEPSYKHVAYHYFKLRLLQSEILQVLQYNQTQVVRASGQNLTNSDMHTHLPSPFLVKFDSFRSWRIDIDRRLYQWKNSAPTREETGVAFSTEFLELNYWQAIIMLYRQSLSVPAMFEGEYNTSTEVNSPTAFQAELREDEDRIYLKVAEAGQKILRIYRQLHLSGLVSYTYLSTHHLFMAGISYLYAIWHSPIVRSRLTMDEVDFTILAAKSVFTDLIDKCPPAETCRDAFDRTAKATIKMANSTGGFNSVPPRKMRERQFEWSSASGDGASTSTASVAPRRRHQQHQSSGQGNFQMDMALSDTLSSPSLSVAGDLPPRHSPRATDFNVMAPSQGSPSEIDPSFVASPPVPRRVATQRTSSGGSFLNQQQQQGPSTYGVADYPDIQTMDFFQSLQGGNPNGELGGSGDVTTPQLDLGFGINWDNMHHDFSEGQQMNIFDGFFFGGQQQSQAQQQQQQQQSPDQQQGPNGNTNGRNGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLN8</accession>
    <name>A0AAD8XLN8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_726996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369658.1">
        <property type="nucleotide sequence ID" value="XM_060512770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLN8"/>
    <dbReference type="GeneID" id="85396668"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042225364" evidence="2">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="37153" checksum="A965D807F5185CB8" modified="2024-05-29" version="1">MHMTKVTAILAFAASLAAAAPGAKLVPEKRQTTEFGPYPEDSYQGKENGKRQTTEFGPYPEDSYQGKASQRRQTTEFGPYPEDSYQGKENGKRQTTEFGPYPEDKYQGKENQRRQTTEFGPYPEDKYEGKTKRQTTEFGPYPEDSYQGKENSKRQNTEFGPYPEDKYEGKARRQTTEFGPYPEDSYQGKSSKRQTTEFGPYPEDKYEGNSMKEKRQTTEFGPYPEDKYDSNNMKEKRQTTEFGPYPEDKYESTNSKRQTTEFGPYPEDKYDSNNMKEKRQTTEFGPYPEDKYEAKNSRRQTTEFGPYPEDKYENSDKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLS5</accession>
    <name>A0AAD8XLS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_567858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369699.1">
        <property type="nucleotide sequence ID" value="XM_060503999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLS5"/>
    <dbReference type="GeneID" id="85387898"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="709"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="772" mass="84312" checksum="39B1E487E5D58A10" modified="2024-05-29" version="1">MSRQPLRYARRPIYILVTYLVLLVAPWLCVCIINRKTTSDPWGIIMRQDLDSYHRWIAAASFFSTVAAVIALPCVAALLAYGAVVFSQRRSKQQTLTVRQLLAISDLKWTAFVSSGQSSSYLLLATGLLLLTAVQPPLQSLLMPPSSRPVYSCDSLRPLSKWDRTCDGKGQPAQAIGKDAEPILLRESNASQIVTTVRTKMVNITSADIQENLWRAEDNHRSFVTGEDQTYNDSFWVSAIPAGVTTGPLRQHSIRLSSTAACQVADEYPANCDGYATSLQGFGISVRTCMPRNNTSPAPRGVPPRRRQDVDEVLYIDAQISPEAAKTQDFLSEPAQNVTIKCIAKTTRAFFEIGNLQTGLVPSDIIGEWPSDEDMAAHFHDYDWQGNLITNESENDWNRDRFSGWTSRQGPLRSTAEALFGNGSYPQAVLDLLSQTFPDGQVPDNTTSDSDAKRRACSLPTPLGAWQLPYNSHNDDYDSWYSSIYQGCSLAELPKTLFRIAQGLQYVKVAQSTLGVGMYLSNVAVLQDAASNDAARTIYNLAGTEFVAPRYTVGATVAISLLISMQAIALIILVCYIYSLPTWTDTLDAFAMMRLGAHLRDSVDFPLVGRASREEMGALDETDGLLGVVVRGAAGRSEEDLELAALASSSTAQRNETSAHQYASVSPLSPTSTVEQDPSAPATQTSHVVDATRPGMDTSELSEYLQGAPPASLTTTTTTTTTVSSPRSPSPPPPYLPARSSNRDQPVRGPFELGLGAPGLITRALWERYRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM96</accession>
    <name>A0AAD8XM96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Factor arrest protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370006.1">
        <property type="nucleotide sequence ID" value="XM_060513535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM96"/>
    <dbReference type="GeneID" id="85397433"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012486">
        <property type="entry name" value="Far11/STRP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07923">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01293">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01292">
        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP N-terminal" evidence="2">
        <location>
            <begin position="107"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="3">
        <location>
            <begin position="509"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1030" mass="114630" checksum="FE55B12272E75A8A" modified="2024-05-29" version="1">MNSLWPSRPANDGAAAEKEPPPTGDVADAVVANAVVADVGPDTSNPPPPPPPRPSLQRNSSAPSPAPLPVPIPPAPMPPAPEPQQPTDSLSLLQLRKIVAEFSRGEPVAYDFVYNDMGVHDEEVDEWFVYQFWQWVRLNAAQRAFEWQWQHDYDIQTTWEETDHQTKAKFTLDALDGLQVKDPTQRSAHIGKVLYLVLGRWGDTSTPDTVGDRRSAASATQLEAIRSSISFLTSLAGIHTVWSALQSCFDVFWSDDARLVQPGGAQEAQDELINLMTIMYVIIQEALSFPKELGATRSELLSLKPGLVDFMSLATSKLRWDDGNLMPSSQIFLLFWKTVLLVFGGTKEVDEAKKATNESPNAKSKDFITASPLDYHVFRQELTSKYPAYVPPRTLIPLEPENTTLLPPIPNQPTRTSAANGIFPGPPTSQSGGASILHQPVHIATPAPSPPPSPGVGGKGGKKQNYQTNQNFPFMYPPLDATSNSAGGKGGAGLQEQLVGRRWEGSDIPASILEAGELFAKRVRMTRATRQLWEERESFLRFERGWEADGDDSDVDNLDLEGLTLEEKQEIAAFKAETKAEERREAQLSMREPEIDCGPSADKVNDEIKRRLLAVESFYKESLPHLQSLVIVLLRPILMNVTAVLSQPPQGQQHPSMAGRGANGGMNGGAGPNRQQQPQDPSSAGGGPPELPEMSPEEVDAARSREITTKAITGILLLLLKWLRVSHVLKSEYMTQLLLDSNYLPLVLKLFAHQDVQQVVDSKTDRLENSFFHFCNLRSKFKEKSPAQAEPDEEESEDEAAPPPIKRRRSPPRVATAATRDGDDTSKLEGQAAMRPEVDELGYPIGDLPAEPITDFSRRNFFSLINYLRIMQKICKHKAHRNLLLVQYKSANILRKSLKIPQPELRLYTLKLFKNQVPYCGRKWRQSNMRVITAVYLHCRPELRDEWLAGSDVDAEVDSALPLEQALRSLTHWSNVRRYPDKIAAELRAALREEQDFFTRELEKLDMNWADVGADDGANSEWEHDAAGWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM3</accession>
    <name>A0AAD8XMM3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_647026</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370305.1">
        <property type="nucleotide sequence ID" value="XM_060510033.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85393932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000048">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000067">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1115"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1148"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1192"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1226"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1253"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1085"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="313"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="394"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="649"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="649"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="651"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="651"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="762"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="806"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="840"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="869"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="950"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="951"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="952"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1032"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1038"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1058"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1061"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1062"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1062"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1730250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1283" mass="141438" checksum="BFDEE8B52DCE5B7B" modified="2024-05-29" version="1">MPSSTSYRSADPPGSPGNDSDSDLDLDIQELDPATTTTDRTPGLLRHDRQTTEHRSPRIALRNLRMGGSRRAGQKARGYGQLGQDRDGTSEDAEALLGGPGSSSSRYRDGSAGAGSDDDSPLLPGGSPPRRRSFAGDRFERLTSSIRLPSFMSNSGAQEPDKDDAQDQDEDDPSSARLVAVGSSQATRFPPNLISNAKYTALTFLPVTLYNEFSFFFNMYFLLVALSQAIPQLRIGYLTTYVAPLAFVLFITMGKEAYDDIERRRRDNEANAEAYTVLSFDEPGRGMASAQRTHKRLKSDSMRKKGKNLAGLRDRLSDIQEEEERAEGEGSIAQPSASVREVSRKSRDLKVGDVLVLGKGQRVPADVVILKCITSETTTEAPVMEVIAEEESLLVDAEEDQSKAPQISDAKGKEPESNDASGGAAGETFIRTDQLDGETDWKLRLASPLTQNLTTEEFVRLRVTGGKPDRKVNEFIGTVELLPSKRDAQSQQGALNGDEGNSAPLSIDNTAWANTVIASNATTLAVIMYTGPQTRSALSTAPSRSKTGLLEYEINSLTKILCALTLALSIILVALEGFENTKQNVWYIKIMRFLILFSTIVPISLRVNLDMGKSAYSWFIQRDPGIAGAVVRTSTIPEDLGRIEYLLSDKTGTLTQNEMEMKKIHVGTVSYANEAMDEVTSYVKQGFHIQPTTDPSSHTMLITPSSTFANASNVGATRTRREIGTRVRDVVLALALCHNVTPTTEEEDGKTIVSYQASSPDEIAIVRWTESVGLRLAYRDRTSMILESTENGREIVRVRILDVFPFTSEGKRMGIIVQFFDQTQSTVPNLANSEIWFYQKGADTVMSPIVAENDWLDEETSNMAREGLRTLVVGRKRLSYEQYKEFTSSYQAASLAIAGRDAGMQRVVAQYLERDLELLGVTGVEDKLQKDVKPSLELLRNAGIKIWMLTGDKVETARCVAVSSKLVARGQYIYTVSKLKKKDNAQDHLDFLRGKTDSCLLIDGESLALFLTHFRIEFVSVAVQLPTVVACRCSPTQKAEVAKLIREYTKKRVCCIGDGGNDVSMIQAADVGVGIVGKEGRQASLAADFSIEQFYHLTKLLVWHGRNSYKRSAKLAQFVIHRGLIIAVCQTMYSIAIKFEPDGLYKDWLLVGYSTVYTAFPVLSLVLDKDVDENLANLYPELYKELTSGRSLSYRTFFVWVAVSIYQGCTIQGLSQLLTEVDGPKMVAVSYTVLVLNELLMVAIEITTWHPAMIISIVGTFLIFVGSVPFLGGYFDLQFIITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMR8</accession>
    <name>A0AAD8XMR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Phosphatidylinositol transfer protein SFH5</fullName>
            <shortName evidence="16">PITP SFH5</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_788434</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)</text>
            <dbReference type="Rhea" id="RHEA:38691"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:38692"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Endoplasmic reticulum membrane</location>
            <topology evidence="2 16">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Microsome membrane</location>
            <topology evidence="16">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the SFH5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370222.1">
        <property type="nucleotide sequence ID" value="XM_060515679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMR8"/>
    <dbReference type="GeneID" id="85399577"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017157">
        <property type="term" value="P:regulation of exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042938">
        <property type="entry name" value="Sfh5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47669:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SFH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0492">Microsome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="18">
        <location>
            <begin position="161"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="358"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="9"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="365"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1730167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="449" mass="47513" checksum="FB5C06D0223B81FA" modified="2024-05-29" version="1">MSAQTTDTPVAAPAPAVAAEAQPAAAAPAAEPTSVDAPAPAAVAAATPEVKQEQKTEQPAAAAAEKTEDKADEKAAAPAAEKPVEKAQTPLSSLFEKLPTILAEAKHNEMWGVQLSNDTHVPTTVVLQKFLRANDDDVSKAADQLQKALVWRRDTNPGKLLDEVSFDAKKFGDLGYVTTHKDAQGKEMIITWNIYGAVKDKKATFGNVDEFIKWRAALMELSVRKLNLDKVQTAIPDGGEDPYQMIQVHDYLNVSFLRMDPAVKAASSETIRIFAMAYPELLVHKYFVNIPALMGWVFKAMKVFLAPKTIAKFHPLGYGSELGGELPAYKDSLPKDYGGNVEGIKITGQTVKFAEAEAPVEKPAADATPAPAVAAPAATETQPTAEAPAAVTAETPAPAVAVSEPGVASEPVKAAPSSAEAEKTEVPTVADLSIKDKTEAKEEAKTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN76</accession>
    <name>A0AAD8XN76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_566603</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370438.1">
        <property type="nucleotide sequence ID" value="XM_060503864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN76"/>
    <dbReference type="GeneID" id="85387763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000006">
        <property type="entry name" value="3-isopropylmalate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979:SF1">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="5"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1730383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40428" checksum="3BE3817EB1838571" modified="2024-05-29" version="1">MAEHNIVVFAGDHCGPEVIAEAIKVIKTVEKLSPTAGKFNLQDHLLGGCSIDQTGSPLTDEALAAAKAADAVLLGAIGGPEWGTGAVRPEQGLLKLRSEMCAYGNLRPCFFASDALVESSPLKASVCRGTDMIIVRELTSGLYFGERKEYDGTNAFDTTVYTKPEIERIARLGGILARKRGDSRVISLDKANVLATSRLWRTVVDEVYKNEFPDLKVEHQLIDSAAMIMVKNPTHLNGVLLAPNLAGDILSDEASAITGSIGLLPSASLCGVGTAVPSICEPIHGKPSFFFKPSCGYQSLTQMTGSAPDISGKGIVNPIGTILSVAMMFRYSLNLGHEAKLIEDAVRVAIDAGLRTKDMGGNTSTAEAGDLIVAELSKILKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNY0</accession>
    <name>A0AAD8XNY0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monothiol glutaredoxin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_341971</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370886.1">
        <property type="nucleotide sequence ID" value="XM_060502461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNY0"/>
    <dbReference type="GeneID" id="85386360"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000092">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="27800" checksum="26C34D119585E875" modified="2024-05-29" version="1">MSTITEITSLADWEKHIASTPPSTLHIISFHAPWAAPCAQMATVLSTLASEYPVTSPPQTSWVSINAEELSDISETYNVTAVPFLVLLRNGQVLETVSGSSAVKVRNAIETHAKKPAGAAATVNGNQGVENGPGAMQVDEPVDPAKAKEELFKRLAELVKAAPVMLFMKGTPSSPQCGFSRQLVAILREHSVKYGFFNILADDEVRQGLKEYAEWPTYPQLWVDGELVGGLDIVKEELSNDPEFFGPYSIKASGEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPG4</accession>
    <name>A0AAD8XPG4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_646456</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371079.1">
        <property type="nucleotide sequence ID" value="XM_060509967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPG4"/>
    <dbReference type="GeneID" id="85393866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000611">
        <property type="entry name" value="Protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF196">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE SWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="817"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="597"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="767"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="617"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="670"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="699"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="773"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1206" mass="130782" checksum="7E43D9328ED9A64F" modified="2024-05-29" version="1">MSFSNSSGGTLTVPSPTHVHHVDVLASSVRSLRRSLSRSPSKFSLARTSSPSSESSHSGSHTPVQEQSPCRRYTPTPTPPSSSHNNINFGDFQSHTPAGLPPSMTSTTPFSSPPTLATPFRPSVRLSLRSAKSAKAIGSPSRPATRLRTSPKSPLKRALNATTDSGVNSTPSSSSSSEASGQENNQSSAQQSPRSRSSLQKSSRHSLHLDVSGHAQQSNIFKHLEGQGDSQGAPGSGALKRSDAIMNLDQASLGSPVAKRRSLHGISSFGQNASDFTIFDNTSNTPSKTNFDIHDEANREREYELFGSPSVPAPREPLPSPTPPQIPRRTGSLRRSTLQQRQHDRSSWGRKSGASHLAQMSGDFSTPNVKNRPRLSMDQFLPPQLPRDSPFNSNGPLPNPSAHPIERSSHQPHPLSKTLVTSTSGNSLEEQNNSMPPPYVFEKPRAPLNFAKSMPYGSSRPLFMQEENETVTPFKAAKPWAGAFMSTGLVSKVNRNPEEDNKLTMPDTPCKKPTNGFATFPPPPGSAIKKNNRYSFGGMPSTPFVAPGAPSRSTFGGNPGKGLGIFQRLGSRHARRGSVLSLDDDKKFSLDTNFNIGLGADIDAPPTPTKHGLTPSKGLTPSLSNLSEQSIESPSAKRSLPPPMSAVRPMISRESTGMYTAQERSDDKSTSCPLPSSPLGSTSSLADRLSPTQRLSLPSFGQSRSGRGFSAPSPLRTRLCTSTADCDHQMDMLAKITPHHIASPVEQRSPRTPSSHVLLPDASCLSISNPAESTRSTTTPVTPSGRESFQSTSTHLMTPVNAGRGGGDVEDSLYSRFDKVEMIGKGEFSSVYRVVKNGYSRASFLSVFSGTPTKNPRESPEPDRIYAVKKARRQFTGPKDRLAKLREVHALQALTHADHVIHYVDSWEYNQYLYIQTEYCDEGTLDKFLSNVGRKGRLDDFRIWKVIHDIGLGLQSIHEAGFIHLDLKPANILITFEGILKIGDFGLATEWPAAKGVDAEGDREYIGPEILRGDFNKPADIFSLGLILIEMAANVVLPDNGPTWIALRSGDLSEVPSLTFSATTTTSSYRDAAGVPTMQSLDDPLLGQTSAPDISLHSGIAPTRVNVVMDDESSPFITRKRTELRSPPDFMSDPFHPSSLDQIVRWMVRPEPSERPTIQQLLTTTAMSWVAERRRSAATVFEGVWGPSESTALPTLVDEDTEMMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPL3</accession>
    <name>A0AAD8XPL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsular associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_715349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371154.1">
        <property type="nucleotide sequence ID" value="XM_060511741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPL3"/>
    <dbReference type="GeneID" id="85395639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF22">
        <property type="entry name" value="CAPSULE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="1">
        <location>
            <begin position="323"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="645" mass="73465" checksum="F969D97133005B89" modified="2024-05-29" version="1">MAWRANRPPPSSAKPLLKGVLAVFILILFLTSTYMYRDTISSNASRIKFTDGAATDYFKYPFNASNADANPIDWLIHDARTKQAAVLQKRSRTLHNAAQRYRERRGRHPPPGFQEWFRSAMDTDAIVVEDFFDRIYDDLRPFWALDPKTITKQANAGDHIVRVRNGTATEQGNTEGKEPWLELWTALVAEFAQHLPDVDMPINYMQEPRILVPRKDMEKYVAKEEKKRTMPTKNKATSVFQSLVGVDATQGKSASSVKWTSGDRRKYWDLVREACPSDAPAKNVPAATDLSLPPTLPYSWTAPFARQGYVQNFTSSMDPCVQPHLRSLHGTFVEPLHVNTTRDLTPLFGGSKLRVNSDILIPGAMYLSDDRSYTGGNVRGPAWPEKRDCLVWRGVGSGGLAKSDNWMHFHRQRLVEMLNGTTVRGMEANDVRAMTFDMPPLDRYDTKRRRDKRLGAFLSRFADAGFTQLLCGPGAHDRRRGEEEECDWLAPHLSVVNGTPMAEQFASKFLPDADGYSFSGRFRAFMLSTSVPLKATVYAEWHDDRLTPWMHFVPLDNTFQDLYGVLDFFTDGNDDEPRGWGVHKVLGKKSKGDDAARWIAEQGKEWADKVLRREDMRLYVWRLLLEFARVCDEHRDTLGYVVDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPP4</accession>
    <name>A0AAD8XPP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_565254</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371276.1">
        <property type="nucleotide sequence ID" value="XM_060503731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPP4"/>
    <dbReference type="GeneID" id="85387630"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12614">
        <property type="entry name" value="RRM1_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12619">
        <property type="entry name" value="RRM2_PUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000117">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000224">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000134">
        <property type="entry name" value="Nuclear and cytoplasmic polyadenylated rna-binding pub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF5">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="87"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="177"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="303"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="52016" checksum="153FCC7D9BBE5B05" modified="2024-05-29" version="1">MADNGPASNAAQLPPPPQPNTGAPGYENGQNGQSNPAHMPPPPLHIPQNNNPIPTAITSPMSGVDKVMSPGSAGGFGRRAAPEPNKRALYVGGLDQRVTEDVLRQIFETTGHVQNVKIIPDKNAKGYNYGFVEYDDPGAAERAMQTLNGRRVHQSEIRVNWAYQSNTSSKEDTSNHFHIFVGDLSNEVNDEVLTQAFSAFGSVSEARVMWDMKTGRSRGYGFVAFRDRPDAEKALSSMDGEWLGSRAIRCNWANQKGQPSIAQQQAMQAMGLTPTTPFGHHQFPAHGVASYEVVLAQTPSWQTTCYVGNLTPYTTPNDVVPLFQNFGFVVESRFQADRGFAFIKMDSHESAAMAICQMNGYNVNGRPLKCSWGKDKTPNPQGGAAAGFDPSQQAYSPQSAASGPGGYPGTPTAYFPQYGGQYQGQHGNYGGPAAQSPAGYGAQPMGYGGPQSAGGYGRGQQPPNQQWPQGPQGQNFNNGFAGYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPU6</accession>
    <name>A0AAD8XPU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_773484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371395.1">
        <property type="nucleotide sequence ID" value="XM_060515406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPU6"/>
    <dbReference type="GeneID" id="85399304"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="310" mass="33261" checksum="B6DFEDACFC3A24DB" modified="2024-05-29" version="1">MGDVQRTFGGRVAARVSFASVNVRLDPYLSITGNVQSRGANCDETATTCVSPPGPKLEFLEAQRGQRHCALPARCNDQSLRTCFLAALSRNLVSPPVPGHGPSSRSPIKPFPPRVISLVPLADNVSTRIGTNLPGFPNSLPVLACSCHQVPPGLEATSQSRKYVPLIVSDLSCKCEQCLRLQADQAGFWEAISLFPAAASPTTHSSQFPVPFLIPPLALTFTIHRSPYRSGLRYLTGALSHVNLPSQFCAIHSQTKRGSPGTVPILAFPLPGSAQSSHPVSRSSHKMQIFPTGDIPSRTSLTTHLARPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPX0</accession>
    <name>A0AAD8XPX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_715195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371414.1">
        <property type="nucleotide sequence ID" value="XM_060511722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPX0"/>
    <dbReference type="GeneID" id="85395620"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039258">
        <property type="entry name" value="ZNF511"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21354:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="29040" checksum="DA36A58D245AB8F9" modified="2024-05-29" version="1">MKRSREAEEEHPSSGISADERSSPGTSTPDDRAAKITGLEPAVEGASEDFAMKCSLPPHKEALTFKTYDDYEAHYIATHTNRCLECGRNLPSSHLLNVHHEECHDSFAAVKRERGEHTYSCFVEGCERKCMTPQKRRMHLIDKHGFPKNYFFAVTREGIDGRRSLLVEAGHHRRKSSNALSATKDSKRRSSILDAARSQGGEDSQKAGDAAAKPEANSVPAQPAITERPDTEMEDLAGAMSALNFVPNSVRFGRGGGRAGFAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQD7</accession>
    <name>A0AAD8XQD7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_597733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371563.1">
        <property type="nucleotide sequence ID" value="XM_060506912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQD7"/>
    <dbReference type="GeneID" id="85390811"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042259426" evidence="1">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="64" mass="6918" checksum="D77D3446BB58EA69" modified="2024-05-29" version="1">MQLSTIFFALFAGVAFASPASLETRQNTACDLCRKDCFFGKGSNAVFEKCLNTCNKDLGCTLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQE6</accession>
    <name>A0AAD8XQE6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I phosphodiesterase/nucleotide pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_597774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371578.1">
        <property type="nucleotide sequence ID" value="XM_060506915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQE6"/>
    <dbReference type="GeneID" id="85390814"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.180:FF:000003">
        <property type="entry name" value="Type I phosphodiesterase/nucleotide pyrophosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="763" mass="85750" checksum="776F95D2503E4DF3" modified="2024-05-29" version="1">MSIRHPSARSRADRDNTSLLAPDTYDDDASSIHSTRSDQDSDSDDDQLQLRARNSRELRAADSLVFMEEEEIENLVEETRKKKELQRRGSGLAVPNPLKLFGRGPDGQRPGSRDGSSENLLDEKDRRQQRRMRRKQKKDRLLEKATHGEDGELMYEMEEGAMKEGSSTGESSERDDSDELDRQRLKIVTKAKSDKRRTWRRWLLIHSMIAVGFAILFLVAWKLSIGSRSAHKADFVSNGTALFAPTTIIISLDGFRADFLQRGITPRLNAFVKEGVSPKYMLPAFPSVTFPNHYTLATGLHPESHGIVGNTFWDPDMQAEFYYTDPARSLDAKWWSGEPFWVTAERQGIRSAIHMWPGSEAHILGVEPTFLDKFNGKEVLDNKVSRILEFLDKPGMEDKTAKVEDMRPQLIAAYVPNVDADGHRYGPNSTEIRVSIESADAMMDQLFLALEQRNLTNIVNVIVVSDHGMATTDTARLLQLEDLVDTSKIEHTDGWPLYGLRPKNPDDLQGLYDGLVEKSKTNPNFEVYLRDVNMPERYHFSKNKRIAPLWIVPKAGWAIVTKEEMDVEKALKDGTVYNPRGLHGYDHEHPLMRAIFIARGPAFPHPPNSQIDNFQNINVYNILCDSVGLIPEPNNGTLRLPLTTMGTHKSEDTPPEPEDPVPPYTTTQVPAPTSTPPAGQSATPDKSIQVDPVPQPTPSAPASNDNEKGDDEESEGADEDAMQKGKEAMIGVWDWLKDKFGKVWDKIKGSKGDQESEEKEGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQF8</accession>
    <name>A0AAD8XQF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain binding protein 11-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_646077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371632.1">
        <property type="nucleotide sequence ID" value="XM_060509918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQF8"/>
    <dbReference type="GeneID" id="85393817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="30396" checksum="F6993AA5E6DDB2B4" modified="2024-05-29" version="1">MPKEKSYNPVNAQRKADKAKAIKKGKAEVQGRRNEKLARRNPERLQKQIDDLKGITTNGGKLSRHEEQVLEGLEKELRAVNKAREALGDKAPTFSRGGGGYNRDGDSSGGVLGKRRRDNDELTSDEDVPDDVKRIPMPRDTPPPIPKELMDKWYAKRRARRQAEQAEREQPEEREKKEKEAKTPAPEPKTVYEAKPMVRNLTKEAVTAFVPTHVKMKLDKGKGQGGLMEPEEADRLEQEGYLQTTASHGDSENTKPHQVMVEEVEDEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQJ6</accession>
    <name>A0AAD8XQJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_597149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371952.1">
        <property type="nucleotide sequence ID" value="XM_060506886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQJ6"/>
    <dbReference type="GeneID" id="85390785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="67" mass="7361" checksum="3D0421772295175A" modified="2024-05-29" version="1">MDMEGGGGARSSHRIARCLSYTTLCREMRNCVLRMARVVCTQGASPGPAVWAEQACRETQTTDITLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQN4</accession>
    <name>A0AAD8XQN4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">fumarate reductase (NADH)</fullName>
            <ecNumber evidence="7">1.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NADH-dependent fumarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_645774</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371858.1">
        <property type="nucleotide sequence ID" value="XM_060509886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQN4"/>
    <dbReference type="GeneID" id="85393785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000007">
        <property type="entry name" value="NADH-dependent fumarate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="542"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="496"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00067004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="626" mass="67463" checksum="6C619339F1CBE0F2" modified="2024-05-29" version="1">MAPRVIVVGGGLSGLSAAHTIYLAGGNVVVLDKQGFFGGNSTKATSGINGALTRTQVDTGIADSVKQFYDDTLKSARDKARPDLIKVLTYKSAAAVEWLQDVFNLDLTLVSRLGGHSQPRTHRGHDAKFPGMAITYALMQRLEELAETEPERVEIIKKARVTGLNKDGNTITGVSYEFNGEEQKVDGPVILATGGYAADFGETSLLKKHRPDTFGLATTNGTHATGDGQKMVMAIGGNGIDMDKVQVHPTGLVDPKDPGSKWKFLAAEALRGEGGLLLNADGDRFCDELGHRDYVSGMMWKEKDKNKFPIRLILNSKASKVLDFHTRHYSGRGLMKKMTGAELAKEIGCSPDHLQKTFTTYNAIADGKQKDPWGKKFFHNLPVDINDDFHVALMEPVLHFTMGGIEINDKAQVLNSEQKPFDGLFACGELAGGVHGANRLGGSSLLGCVVYGRVAGDTASNYLFQQALNGAGGATSRLGQISLHLDPAQPGRVTIDWNNGGGSGGQGIPAQQTTSAAGPTPEKADGQKASKPNNPKEFSVPEKEFSMEEVAKHNTKEDLWVVVKGVVMDLSNWLEEHPGGPQAIMNFMGRDATEEFEMLHDDEVIPKYAPQQVIGRVKGQTPSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX9</accession>
    <name>A0AAD8XQX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Repair protein Rad1/Rec1/Rad17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_714873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371969.1">
        <property type="nucleotide sequence ID" value="XM_060511678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX9"/>
    <dbReference type="GeneID" id="85395576"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003011">
        <property type="entry name" value="Cell_cycle_checkpoint_Rad1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01245">
        <property type="entry name" value="RAD1REC1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01246">
        <property type="entry name" value="RAD1REPAIR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="35742" checksum="7DCCC2E25770692A" modified="2024-05-29" version="1">MSAALPQPSAVPQPLFRAVASSTRPLYQLLRTISFSNKVHVQLQEDGIRFAADLSRVMQGTAFLDKKLFTSYSLNLAEDEPLPNFQITLPALLETLQIFGAVDIATRTQKAEQDPYRSNLRNYRPDAFSNQTLGIGGTCSLVYTEEGGQFNIIIEESGVKTTASLTTYLPEIPEEIPFDRENLFFKIIMQARYLLDALAELAPTGPSRLTISASKSQPYLSLSGAGDLGSSSVDFAKGRELLETFSIQDRWTQTYKFDLIKSSSEAMRIASKISFRGDAQGVLSLQFMVEVEGGGVSFLDFRFVPFITHEDDEDEEGQDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D184</accession>
    <name>A0AAD9D184_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">30S ribosomal protein S13p/S18e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_448530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369964.1">
        <property type="nucleotide sequence ID" value="XM_060503154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D184"/>
    <dbReference type="GeneID" id="85387053"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="119" mass="13407" checksum="BAFF76CF96584CBD" modified="2024-05-29" version="1">MVFILGVNFSEQKLVKKALESFFALGPTTSSRILAKYSISPMSKVGALPPKTVTALTAELSTMTIESDARKIIQQNVMRLKDMGSYRGRRHAMNLPVRGQRTRTQIESARKHNSANRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2C2</accession>
    <name>A0AAD9D2C2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_715650</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370670.1">
        <property type="nucleotide sequence ID" value="XM_060511769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2C2"/>
    <dbReference type="GeneID" id="85395667"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000107">
        <property type="entry name" value="Mitochondrial dicarboxylate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="66"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="161"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="261"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="38935" checksum="F4473682CD9BAEA3" modified="2024-05-29" version="1">MQSAAANMVASKPADEPSGPSSSQPSPLKLGQLEGAQEKSQTQSQQTSAATTTTPAPQKQKKTAEPSLRYPFWFGGSASSMAACVTHPLDLVKVRLQVRRPDAPKNMVGTFTHIIRNHGVTGLYNGLSASLLRQMTYSTVRFGAYEEMKIRATRANDGKPPSFPVLVAMASAAGFVGGISGNAADVLNVRMQQDAALPAAERRNYSHALEGMLRMAREEGIMSWFRGVLPNSMRAAAMTASQLASYDTFKGMLIRHTPMGDNLTTHFTASFLAGVMAATVTSPIDVIKTRVMSASTQEGLAHTLAKIYKAEGLGWMFKGWVPSFLRLGPQTICTFVFLEMHRKVYRKVADIGNGEDASIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Z6</accession>
    <name>A0AAD9D2Z6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_787409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371344.1">
        <property type="nucleotide sequence ID" value="XM_060515665.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399563"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1272"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1298"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1311"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1324"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1371"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1434"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1458"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1483"/>
            <end position="1498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1731289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1508" mass="167472" checksum="20647BD574BEEDB0" modified="2024-05-29" version="1">MARRRARDEPQEEVEVEEEQGEELVSLQFDEELTWKPGKPIPTTELLNRLQALSEELGGLDQDTTEVESLNDVAYALGQRNLLAHKDKGVRAYAAVCIADILRLCAPDAPFTADQTKMFFNLVVTHVFPSLSDQTHPYHSQHKYVLTALTDVKSILLINDIDGADDMLLKLFSVFFDGVSGSSNSGPEEGVSKEVGNTMTEMLIALVDEASGMNPKVIEVIMAQFLRAAPPGGFQSRTERSEQNGNQSTLLPKDEPPAYIMAKEICNVCTEKMVHYVSQYFSDVILDASRFAAKTVGKSHEDEEDEDAPRGPTDAELKELRKAHYLIRELWRASPSVLQNVIPQVEAELSADNVDLRQLATETLGDMISGLGAAGPPPPPVLDPAQYPPLRLADEAPSQISDSVLTTPLSPQSFAQTHSSAYNHFLGRRNDKTATIRAAWTNAVGYILATSAGGIGLSREEQSELVKHLGEKLNDGDEKVRLAAVKVMELFSFRDFISKLAAPGGVDKDGSVLSSLADRCRDKRTAVRVDAMTLLAKLWAVGSGELAAGQESVVAALSGIPSRIFNAFYANDSELNILLDRVLFECLVPLSYPPIKAPKSTRGASQSSQNAGVADQDRIRAERILLLTQSLDQAAKRAFMAMQGRQPQFAQVLEAFVKQCESYNGGVIDDNRPKITANLERTVQYITQFFPDSFKVKTDLQKFANANDRRAYQLVKFSVSAESDYKTVRQAIKELVKRTNASQNATILDTLLPLLYRSACLLFNRSHLATILDYSRNDKDGLGSVSHEILNEISQRNPELFKTHVGGLCKGLVEQAPTETNENDSNVVDTLKACASYSKKYPEEIPQDRKFSQALVSYALYGRPVKSAKYAIKILLAKGDDKGLVSATSLLEKIMEDWTYGSAHFLNKLQSVAQLELQVPKITLDSDDDILNMTVQQILLKVRTDATDKDPEWVDDASVDEELQAKCLSLHILVNRLRSMDDVEEAKEKAVPVFKLLKTLVAKRGELCKTKDTPNHHKSRLRLLAAQLLLKLCTIKHFDDFLTPADFNRLAFTAQDTELTVRRGFIEKLQKYLVQNKLRARFYTIIFLTAFEPNNDLKQRVETWIRSRARALGANEQHPMEAIMGRLISLLSHHPDFNKPENVNDASEEELSSYASDLADHGRYILYYLTNVATEENLGLIYKYAERVKQTRDAISPEASENLYIVSDLAQAVVRKWQERKNWSFQAYPGKVGLPIGLYTALPSHQVAQEIAEKQYLPSEIDEKLDGLFKSIDRKKKRKSTDDRGDHHPAKKARSAPRVREPKAPKEPKPKKQKVKKPAKVKAPRRESDIPLENRRRSGRAATTAVSKYTERDSSDDDREMWDGVSKWTYENEDGEQTEVSDDDDDSSVLSEAPEEENGEGAKKPTAAADDSGDDSPLSEVEDVAAEEPGKEEVEADDEEEPEEATPPPKSNGRKGRSAAAASKAAAKTKLPARPAAKEKPAPRATRTSARSTRGRAAQESMDVDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3I7</accession>
    <name>A0AAD9D3I7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371749.1">
        <property type="nucleotide sequence ID" value="XM_060513210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3I7"/>
    <dbReference type="GeneID" id="85397108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF4">
        <property type="entry name" value="ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G01890)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="32302" checksum="1E514B41589598C8" modified="2024-05-29" version="1">MSTLPSSYNTLSLPQITLSHHPASSPTPTPVIILTLNRPSARNAFTDEMASSLAKAYTLLSTDPRVKAIVLTGSDPSNKTFCAGMDLHNRVRLPSHRDAHRDTGGLVALAMHNCSKPIIAAINGSAVGVGITMALPASIRIVSRDAKIGFVFGRRGFNMEACSSFYLPRLIGAGPALHLCTTGGVYPATSPLLRNLFSEVVAPDEVLPRALAIAEDVAANVSTVAVRVMRDMILRSPASPEEAHLLESKIFFDLFSGKDSKEGMESFMQKRAPRFEATMEKDAPTAYPWWKEVDIKAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U530</accession>
    <name>A0AAD8U530_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_209488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000249">
        <property type="protein sequence ID" value="KAK1705040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357541.1">
        <property type="nucleotide sequence ID" value="XM_060501703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U530"/>
    <dbReference type="GeneID" id="85385602"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="79" mass="8603" checksum="01354F8D8D850B53" modified="2024-05-29" version="1">MRWTLLFQPSIPSNPSIPVGLLGTLLDRRGSGPSSEGRTLGRCTFTPYLGPRHPPVGDSGVGGRERRKERCSGKLVWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U676</accession>
    <name>A0AAD8U676_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_758130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358152.1">
        <property type="nucleotide sequence ID" value="XM_060514990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U676"/>
    <dbReference type="GeneID" id="85398888"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="511"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1707936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="61638" checksum="30C6D767F32082F0" modified="2024-05-29" version="1">MDFEPTDVLIVGAGPVGLVTALSLAQQGIPTIITERRQLEVQESFGRAITLFPRTLELFEQVGVAEEIVQQGNIVRGIATFRGGKRVSAVGQQSMFTAMTGTFHDYIINIRQKSSQAIFAAKYKAVSGNEVQYQWELVDYQIDDKPHDGYNLTAVLQHPQHGTRSVRCKYLVGADGVSSQVRQLAKIEMIGDETAYEWVRFDGRVKTDIPETDLGFVTINSAEYGSAFLARVDKDACRLGYVFTPTLKAKYPQGLSKEQAMEEVVKSVQPFKLEIKQKVAATMQKDDFIFLAGDAAHTHSSGFGQGMNTGIHDAINLSWKLAGVLRGWYQTEVLDTYSEERRAVAQKVIDIDKTLAAVLSGDVPETWTGCSGKPEPSKVLGDILTSNASFNIGLGVSYGPSVLVDRATTGSLAVGHRCPDILLRAPGPSVPIRLQSIIHKNTGQWNMLIFAGRPGQQTAKVAALRDTLESLNAVNKYDQMVSFTTIVTGTITNTWDVYDGLPSSLVLCDVDGQGHNTFGISATSGGLVILRPDGILAGIYPIENVQEVGLLFKNFWSGSTKTLPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U861</accession>
    <name>A0AAD8U861_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_765097</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359251.1">
        <property type="nucleotide sequence ID" value="XM_060515241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U861"/>
    <dbReference type="GeneID" id="85399139"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43576:SF3">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43576">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="309"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1711927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56701" checksum="E5E0CD6957C3A450" modified="2024-05-29" version="1" fragment="single">MATFTKITEDARPSITLNPSHVISKIDDNVYGGFTEHMGRCIYGGIYDPGNPLSDENGFRKDVIEAFKELNCPVVRYPGGNFVATYHWIDGVGPKENRPKRPELAWIGVESNEFGTDEFMKWCEVVGAEPYLALNFGTGTLDEALAWVEYCNSDKDTYYANLRRKNGREKPYNVKYWALGNECWGPWQVMQMTKEDYAKQAYQWAKALKLLDPSLELILCGETGFSSWDTYVIKECITWSLHGLGGSTTASLIDMHSIHLYTASEDHLKNATAPRAAERAIEITGSLIDLARIENKVPPTCKRQKICFDEWNVWDPIRAPGEEGAEEAYTLSDALAVGVWLNVFVRQAKYVGMANIAQSVNVISPLMTTKEGITKQTTWWPLLLFSKYMRGSTIATHVRAPEYEGATEPVWIRGAIETPYLDVSATIDDNGFVNLAVVNVHETKGFSVDLEGVKEGADVQVYTVTGENVKVVNTGDKNPVGITESKWDGKGPYEFAKASVTLLRWKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8R8</accession>
    <name>A0AAD8U8R8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_798321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000329">
        <property type="protein sequence ID" value="KAK1701925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357079.1">
        <property type="nucleotide sequence ID" value="XM_060515926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8R8"/>
    <dbReference type="GeneID" id="85399824"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A2" evidence="2">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1701925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="630" mass="72131" checksum="7D743FD901F3A75A" modified="2024-05-29" version="1">MELGFYIACRMGHLQEVEVFIQDISPSHAIRQFGLQQASFGNQPAVAKFLLLNDTALHGYVFEGTEAASKTRGTAVGASLFETFPDDDDTLVPLLQTFMDAGWHPNQAWEPREGNYPKWALQDPLCVRNKPLAKFLLSYGADPNIGPGWYHIPTLKEQEPNVWYPVEVPFHRHGIWTFGLAIETWNPRFFELLRTYSDPVLRVSELMPLLRIVRDMAVLSAVGQHSGDAERWVSPFSLRREMAEHMLSFDDVDVDDVKWAGERGEQTALTLACATGDWDYVEWLLDKGADPSVLDGIAFAHDPKRLLELMSRAGASDTGQFEDVARPYQIKLKKQLDQFCVPYEIFLNIIEFLVREEVKNTDSLENVLEYDRRSEARIVVSTTGYDDDHYVRINRIRDLLHIDSRSRSMVSKYFPRMVMITRRHWRARFPFMGRVCLATDIFTLKENHEIDFLKASIILPNVKGNEIVRNITAIKESDTKFFRENFENFVDVLGSLPNLRKIVIDGGNYQPKQDDDRCACSLSESHPEFTTIDASHFPSLAKWAEDYGDVAREFGPQFKKRNISIIARVSTNNSKSNLELDITEDAIRVKSDCRNCDCCECWVHEICLDMARLLRQCRLADLRESSGSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8U4</accession>
    <name>A0AAD8U8U4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_541685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000333">
        <property type="protein sequence ID" value="KAK1701856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357065.1">
        <property type="nucleotide sequence ID" value="XM_060503403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8U4"/>
    <dbReference type="GeneID" id="85387302"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042040921" evidence="1">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="59" mass="5979" checksum="45677A1CF723CE98" modified="2024-05-29" version="1" fragment="single">ALGAISLLFSIAEAGCAEVGSGDGNNPLRCKSYSIPRDIGTSVTVGLQTLSIGRTNPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Y4</accession>
    <name>A0AAD8U8Y4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_745901</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000270">
        <property type="protein sequence ID" value="KAK1704083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357376.1">
        <property type="nucleotide sequence ID" value="XM_060513198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Y4"/>
    <dbReference type="GeneID" id="85397096"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF18">
        <property type="entry name" value="ENDOGLUCANASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221041" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="16"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="16"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1704083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="234" mass="24411" checksum="365BF97D8749EED9" modified="2024-05-29" version="1">MKLLSLLAAASLCQAHTIFVSLEADGVNSGVSQGVRTPEYDGPQTDVTSQYIACNGDPNPTKSTDKVITVTAGSTVTAVWRHTLTSGPEDVMDASHKGPTLAYMKKVTDAKTDAGTGAGWFKIQEDGLSSGVWGTERVIGNAGKQAITIPKCIANGQYLLRAEMIALHGASSYPGAQLYMECAQINVVGGTAAKSPSTVSFPGAYKGSDPGITINIYYPVVTNYTIPGPAKFAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9K6</accession>
    <name>A0AAD8U9K6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_588711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360001.1">
        <property type="nucleotide sequence ID" value="XM_060506164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9K6"/>
    <dbReference type="GeneID" id="85390063"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="29815" checksum="F999417F410ADA3A" modified="2024-05-29" version="1">MPRLFSKSELRRFEDCANENQTLADCWAGDQIVIVACELSDKYQYADKRNSRAIEINVMSSADKPVWRSLPLDTRQYDALKRHCSTRTIRMLGKSKVNKSLQPKPWSWYNAAAAHETFELYEEEARAKAQEAFDALSGEMYATVCVVSYDLRETMAALDLFKVKLPSSKVVFVDLIKVLEHQTRGEEVIPERLRKYTNDNIAMRNGRLDRRPGTPRGYLGMPSIRLLEVVGPAAEGHRADHKKLEKGNVALERIAKRIRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA97</accession>
    <name>A0AAD8UA97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metal homeostatis protein bsd2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_590406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359267.1">
        <property type="nucleotide sequence ID" value="XM_060506336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA97"/>
    <dbReference type="GeneID" id="85390235"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37157" checksum="5FCF67EDC539B76E" modified="2024-05-29" version="1">MAGRYERVNAQDEDDFNSPNSAPPSHAQTVPNSPPPSFHSRASSRDRAAHGVDSTLADAFDTDGDESDDDADDRQRLVRADSTLTSRDTSRTVSSESRPQPDRQVTQLPPTTASAAGGPTTPFRIYGSGIQNEGVFSNLTAKPERGGETKEEQPPTYEQAAADAAPPYWETTILAPGLGGPDEVYIDGMPVGSLFSFVWNGMISMSFQVVGFILTYLLHSTHAAKNGSRAGLGITLIQYGFYMKGTTEGDHPPKMNGQDGYAAPPDPNSHSFDPNAVTGEGGGGVSDITGQEWIAYILMVVGWFVLIRSVSDYLKARRHEQLVLQSPDRGLPVPIIADGESSERVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAB1</accession>
    <name>A0AAD8UAB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_757385</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358993.1">
        <property type="nucleotide sequence ID" value="XM_060514892.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002145">
        <property type="entry name" value="ABC transporter (MsbA subfamily)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF345">
        <property type="entry name" value="ABC MULTIDRUG TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="897"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="935"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1041"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1113"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="279"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="612"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="897"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1215"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="570"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="843"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1711190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1486" mass="163939" checksum="448D680FAC422FEE" modified="2024-05-29" version="1">MSSRCLNDDSLGPSVQGCRGDFDFTLRFERIFLAIIPAAVFIALSLPRVAYLARKPRIVGAKAFQTMKLAIITVFATLQFAILILQTTSSGSRIDGFAASASALGFLAALFMVGLSYAEHSRAPRPSLLLTGYVFLQILFDVAQTRTSWLVARTFSTQLFARLFTASLVTKLAILIIEAQRKSRWIHWTAEEHSPEETSGLFSLGVYWWLNRLFLHGYRNVLKIGDLYALDRGMIAETMQITLAQELEKGKNRGKNHGLAKDLAKALAVPLLLPVAPRIALIGFSFSQPFFIQTLLEYLQDDNASKNLSYGLIGAAVSIYTGIAVSTALYYYFQQRALYMSRGCLSAIIYKKTTEAALTDTGDAAAVTLMSTDTERIVRGFYSLHEIWANVIEIALGCWLLQGQLGTAFVAPLVVILVCTGVTAAVAKFTGERQSRWMAQIQKRVGLTANVISNMKYLRISGITQPVAEFVQKMRVEEMRIGNQFRWLIIVTALAALAPSMLSPAITFVFAQERLDTTTIFTSFSFLVLLNNPLGQLFQSVPTIIAAFTCLNRIQKYIEGESRIDFRQSAHPSAFQERPSDESPFRDNSDGISLETFPDRKDSESNSTRPAISLVNGSFGWTADKMVLRNITASIPAAQLTLVVGPVASGKSTLCKVLLGEVPFNTGLVSVPSRNAAIGYCEQNPFLSNGSIKDNIVGWSTFNQARYDEIIDACMLRTDLLLLPYGDDTKIGSNGIMLSGGQKQRVSLARALYLISDLLIFDDILSGLDNDTASEVFRRVFGLDGIIRRRKSTAVLCTHAIKYLPLADHIIALGTDGTLAEEGTFADLMRDKKYVASLGVKATDSDTDSDFGSETSNKPTAGQPPKAKRSPAVADEMMEKSRQTGDVRVYAHYFRSLSLTSTVIFVLFSASYSVWNQFPTIWMKYWAEDTLHKSSGYYVGLFGLFKALQLISLMVAGVALIIYMTTSSGTILHQQALKTVIHAPLTFFTTTDSGVITNLFSQDMTLIDNELPMALLNAVLAGFESIGMGAVVAVASPYMAVSYPLLIAFCWIIQKFYLRTSRQLRLLDLESKSPLYTHFLDTIKGVATIRAFGWAHKDIAHNQHMLDTSQRPAYLLAMIQQWLVVTMQLMVAGLAVVLVTLATQLRANSGFTGASLVTLMSWGETLSSLVRFYTQLETSIGAVSRIKTFSEKVSPEDLEGEDIEPPEEWPETGRIEITGVSASYNNEQQATSDGVTTPPHLALKDLNFSIQPGQKVALCGRTGSGKSSLILLLLRLLDPVSSSPKNIEMDGIPFHRIDRSSLRRRIISVPQDAVFLPDGSTIKANIDPFNAATDEECFSVLRAVQLGTFVEERGGLRESMSADSLSAGQKQLFSLGRAILRRRIKDAKFKRRGGGILLLDEVSSSVDHATDRLMQEIIKEEFRTYTIVMVSHRLDMVMDFFDAVIVMDQGRVIETGSPRELVQTEGSRFGELWAIENQGRSRSPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBM7</accession>
    <name>A0AAD8UBM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_132450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358799.1">
        <property type="nucleotide sequence ID" value="XM_060501222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBM7"/>
    <dbReference type="GeneID" id="85385121"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF5">
        <property type="entry name" value="CHLOROHYDROLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="61"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="500" mass="54250" checksum="876D296ED4159BC0" modified="2024-05-29" version="1">MTVSPTKILLKNGVLLIHGEDGRVNPERSNILIEGDTISEIGPNVRITGEDVKVFDCEGKIVSPGFISTHHHVWQTALKGRHVDHTLLEYLPRGNLIGSLFSTEDAFWGELGGALEAIDGGTTTIVDHSSLNVGPEFPPTLVQALIASGLRSVYCYCVPRATSWSPFSTADDYTSSHVLEEWKSLATKGPYGDGRVQIGFTVDNLYQSPDQLKFLYSELRAARAKVITSHGAGGLAFGDGPSVVQILNNHNLLGSDILISHANFPKDGDAELVKKHNVYISATPNTELQMGWPPVALQPEFEANCSLGVDCHSCGSSFMPSQMRLGLQYARTERQENLRRQGKWSRHVGPSAKQVFNLATIGGAKAIGMAGEVGQIRIGAKADLVVFSTDSPSMLPAAEEDPIAAVVLHSSERDVETVIVGGVIRKENGKLLPVSVTDQVEGASDLGLHGKSITWKDVAKNLIQSRKRLNKTAESIDMMAVEETIMDNFYVNRKDMLEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCA2</accession>
    <name>A0AAD8UCA2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_640641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358804.1">
        <property type="nucleotide sequence ID" value="XM_060509503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCA2"/>
    <dbReference type="GeneID" id="85393402"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042275643" description="Secreted peptide" evidence="2">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="8902" checksum="4EB02BCC7EA78E93" modified="2024-05-29" version="1">MGVIIVITLQLSSATALHGSFEPGPLPHMSSPATMITYLTALRTAVAVVIAHGYICLPTVAIVAITTGTRQLRLYPTATKNRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCU6</accession>
    <name>A0AAD8UCU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_641776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358430.1">
        <property type="nucleotide sequence ID" value="XM_060509571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCU6"/>
    <dbReference type="GeneID" id="85393470"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="34971" checksum="CC8E29A6333CB021" modified="2024-05-29" version="1" fragment="single">CVLSSCLSDEQARELCQCAAGDAGSDKSTELYPFDQNDRARHDPMCPLIRLKSQHCSSKLVEVWRLGMLQDREKGDIRNHIINAATKTVAKVTRVHKDLPYGNVHMSLMMGPLLIENGVPQFVPFLSLAPLFRSIEKISDLCYIRSMGGVLFTVRDRLQLHPVDIPTSSVTRCFALSEDRQLYRTERHIPRDRGVKVLMKQIVGSPFWSLREEDRIAETEIIKDVAKASLAYIDILGEESKRHRQNKSKARKEILRKLHKLLDERVEIYLHSIVNKLFDRSLPLGWFCSLSPLILKVYSPRMYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCV6</accession>
    <name>A0AAD8UCV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_118971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359074.1">
        <property type="nucleotide sequence ID" value="XM_060501140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCV6"/>
    <dbReference type="GeneID" id="85385039"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042024884" evidence="1">
        <location>
            <begin position="17"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="183" mass="18864" checksum="182DED654A6AC767" modified="2024-05-29" version="1">MRFFLPLALFIAAAQAQLILGAIALIEFTIEILEAAEVVATVEVSVDAALTGAEAAETAVVEGTITNVGTTVTRAGEAAIELEGDASLSGFGRVATEGPGFAQGTFTYRQQFPLGVGAGRRATANPQISLNFGARTNAVRSGGTTKINFSNPSLSNVRLTNPGGARTSVRIKGQPVTRLLQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD06</accession>
    <name>A0AAD8UD06_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF2961 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_707458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360767.1">
        <property type="nucleotide sequence ID" value="XM_060511546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD06"/>
    <dbReference type="GeneID" id="85395444"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021345">
        <property type="entry name" value="DUF2961"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11175">
        <property type="entry name" value="DUF2961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="63504" checksum="376A26BC23CDB4FE" modified="2024-05-29" version="1">MHLTYPDLVRRLYDLERLAESPLPGERGGCMSSYDRASRYDPKEDKYIDWDANDDGRGIIREEGEWIVAFERRGPGVIWRTWSAMPDVGRIQIFIDDEHNDKPVVDMPFRDLFDRFQGMPHNFPSITPTLSRGRNCFIPIPYNKYAKIRLGPGWGAYYHFTYTSFPKHTTLPHFDGNFDREACLALAAADRELSQRGWSALPRSKGDTMETLTVTIKPGKSHTVRELTGNRAITGMRVVPLDLVQDSHHVAQILRELAIQITWDHDKSPSVWAPLGDFFGSVPGIQTYRSLPQGSTDGGGFYSHWFMPFSDCAEIKLVNDGKKEQKLFFTICHRPLEKSAKHMLRFHAKWHRDVFLEKPKKEGREIDWPLLMLDNGPGRFCGVQMHVWNRWKDPKVPSKDWWYGVGGDKSIDWWWGEGDEKFFVDGEKFPSTFGTGSEDYVGYAWAAEPPFPTFDSAYACQPYIELDANGHTSVCRFHVCDDVPFHKSFEAYIEKYKPNDWGSGNKCLYAVVAYWYQKAGGHDAYESVSVKERYLQRKENSERVGDGGETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD70</accession>
    <name>A0AAD8UD70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_637908</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1713008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359624.1">
        <property type="nucleotide sequence ID" value="XM_060509335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD70"/>
    <dbReference type="GeneID" id="85393234"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000014">
        <property type="entry name" value="Probable acyl-CoA dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000027">
        <property type="entry name" value="Putative acyl-CoA dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="52"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="169"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="282"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="48671" checksum="EE395ABF79654138" modified="2024-05-29" version="1">MSASLSRNLWRIAQPATKTAGCLRRAPITLRHGLAAFSTSSSRRIMETTGFTENQLTVREAVSQVCSEFPNTYWQEHDQNEQDPKEFHAALAKDGWLGIALPESLGGSGLGISEATMMMQTITESGAGMAGAQSIHANVYATQPLAKFGTQEQLESTIPKIISGEWRTCFGVTEPNSGLDTLRLATTAKKQTDGSYLVTGQKIWITCAQVASKMILLARTKAYEDCKKPSEGLSLFCIDIDKSQPGLDMRKIKKMGGRAVDANEVFFDNYHIPANSLIGQEGQGFKIILHGMNAERCLLAGEALGLGYAALTKASEYARDRVVFKRPIGQNQAIAHPLADAYMKLEAAKLATYHAARLYDASKEDSSIRQDQVGVAANSAKYMAAEAAFTACERAVLTHGGMGYAAEYDVERYLREIFVPRIAPVSREMILSYISEKVLQLPRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD92</accession>
    <name>A0AAD8UD92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NADH-ubiquinone oxidoreductase B12 subunit family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_96427</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359433.1">
        <property type="nucleotide sequence ID" value="XM_060516034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD92"/>
    <dbReference type="GeneID" id="85399932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1712576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="89" mass="10214" checksum="8468A39711E0838C" modified="2024-05-29" version="1">MAATRGQKPNITGFDMRAFKEAAGQPRYDPWERAESWRYKGPFTRFNRFKGSFPGLGIATVAFAGYCAYEYFFLTDDHHHGDAHGKDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDS3</accession>
    <name>A0AAD8UDS3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_637462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359706.1">
        <property type="nucleotide sequence ID" value="XM_060509314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDS3"/>
    <dbReference type="GeneID" id="85393213"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="34173" checksum="A7D64BC9754DC615" modified="2024-05-29" version="1">MEEIIPRYISDEDFVKSFKKATTSTAYDQNVRDLVSQALSAFSDQNWDELHETAWKLRVAQRLNFALEAFTVVTRGKLNVFGKTNPTFKSTVNLADALRVTARNMDQESCQQRLNDAHSLFQEVLSGAQDESLLQQALMRLGSFFTDIGDYDEARRFLGRAEGYKNTSKYQLAELRMSWIDIQTNERQFDEASKAYENFLRDPPESGEDKVIRKTVLVRYANFLTNIKWEAAGKAEDSILEGADLQRAHNIYRELCDVFGGISDNADSKLAYLPIQVEGYRDRMRVAEERMEQLKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF16</accession>
    <name>A0AAD8UF16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_756378</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360184.1">
        <property type="nucleotide sequence ID" value="XM_060514734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF16"/>
    <dbReference type="GeneID" id="85398632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000058">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="15"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1715041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="748" mass="81977" checksum="049CD3FB8EAABF9E" modified="2024-05-29" version="1">MAVNRIRGAFAVPRKGETFELRAGLVSQYAYERKESIQKTIMAMTLGKDVSALFPDVLKNIATGDLDQKKLVYLYLMNYAKSHPDLCILAVNTFVQDSEDPNPLIRALAIRTMGCIRVDKMVDYMEEPLRKTLRDESPYVRKTAAICVAKLFDLNPSMCIENGFLESLQELIGDPNPMVVANSVQALSEITETAPETRALVVTPATLKKLLMALNECTEWGRVTILTTLADYPAADTKESEHICERVAPQFQHVNPSVVLAAVKVVFIHMKAVSPELVRSYLKKMAPPLVTLVASAPEVQYVALRNIDLLLQAKPDILSKELRVFFCKYNDPPYVKLQKLEIMVRIANEKNFDQLLAELKEYALEVDMDFVKRAVKAIGQVAIKLESASQKCVNALLDLIATKVNYVVQEVVVVIKDILRKYPGYEGVIPTLCKYIDELDEPTARGSLIWIVGEYAEKINNADDILESFVEGFMEEFTQTQLQILTAVVKLFLKKPGSNQGLVQKVLQQATTDNDNPDIRDRAYVYWRLLSGDLDVAKNIVLSQKPAITTTMTSLPPALLEQLLAELSTLASVYHKPPESFVGKGRYGADEIQRAAIREQRQEAAENPIAASVAAVANGNANSQNNIENLLDIDFDGAAPASAEQQSNINTPDRVASPAGGGNSSAMADMMGLFDAPPPQQQQAANPMSPGAGGGGMNDMMNGFAGLDFGNTGSGQPLPAGMQLHQPAQPQSGEGNGKKTNEDLLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFI5</accession>
    <name>A0AAD8UFI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_635321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360394.1">
        <property type="nucleotide sequence ID" value="XM_060509161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFI5"/>
    <dbReference type="GeneID" id="85393060"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="79" mass="8792" checksum="818515F4EE7D087D" modified="2024-05-29" version="1">MSGLQYFSYKGYGEKLLQEMHYSQAVRVGDNIEISGQDNMKKWAPSRAPILTGIGASKLGQPGMRLEVEVSAYDPKGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG25</accession>
    <name>A0AAD8UG25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_436446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362282.1">
        <property type="nucleotide sequence ID" value="XM_060503075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG25"/>
    <dbReference type="GeneID" id="85386974"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18138" checksum="6027DE619474F4A4" modified="2024-05-29" version="1">MNGETDTIENVSQAHVLIPSVSPLKRGMCVQCVLQRCKSKATQGRAGQKAGSVESFHLLRAPDASLPRSSVVAAKIRGIRSGLARVHDNGVAPHRGPWERRESRQGRRKGLAGQGPRLSRPSRASCHTYRYPKSIEIQSWAFSVLTRFFLQPESRYITLLYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGB9</accession>
    <name>A0AAD8UGB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_583143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362417.1">
        <property type="nucleotide sequence ID" value="XM_060505621.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389520"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053210">
        <property type="entry name" value="ANKRD12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056485">
        <property type="entry name" value="ARM_KRIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056015">
        <property type="entry name" value="DUF7593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149:SF14">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24521">
        <property type="entry name" value="Ank_KRIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24513">
        <property type="entry name" value="DUF7593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="394"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="KRIT1 ARM-repeats" evidence="4">
        <location>
            <begin position="533"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7593" evidence="3">
        <location>
            <begin position="1245"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1512"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="518"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="754"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="794"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="858"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="919"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="950"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1017"/>
            <end position="1233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1570" mass="178058" checksum="5B75BDBCF137C77E" modified="2024-05-29" version="1">MDAQNAAGSDKSKPVATAEKRPGNHQPDDSHESNSKPTKNVDDSIKSPPHLPKDVKPSVIVSRAPPVADDAPVDRDSDAETIVLPGKDGHSPSKARKVKHEDRSDGEPPVLPVPLVPRKNRDASASRDGDKEKTANPARLSETASSLGLKKKRLHDQSARSKDGSSGLSSAPASPPHHRRRSGGHSDSDTGADRRKSPKLSLKDRAKSIDRIPHKRKASRADSDDEAENRKVRRQRISDHNTIEARARLPKEPKSSSSSRREHDGHSGSRTRSVSPHHPRAHRRSVSTQLPANSSNGLSYKKKRLPPPLQSTDYHSDESSASGSPHPRSSKLRNLSTPATAESNMSPAKIAPHKKHLDAHGQTFLARACARGEYDLAKQRLGERPEDLNVADYAGNTPLQIAAINGYEDIVKLLIDAGCNLDCVNYDKDTPLLDAVDNGHLGVVKLLLNAGVNPRKANLSGEEPLDRVSDDLENADDFRAALNEAKSRQGERRRTSEDHHPTDQFDSRSSHGPDSPRRSPAPSASNASGRRAGTVRANKTSNHLLYMSLDDKTLRQAAGKGDEETVTRILQVKDGCDDSEAMVAAARGGHEVVIQLLLALGGANPDPAPVSSMPPEFATPMLAAIGQENIKVVRLLLDQGNFDPTRRFKGETYHEIARRRQGTNWKDEEHMLKESYDAYRKSHRDISKTKSPGRREREKEREKDRDREQDRETKRQGRNELKDEARAHKRNLSSPSRDPEKRKKLSSGRTITSPKEKRRADSFHEDQISPKRGPGRPRKEDRVPTIAVSDREASPALSQKQAAKAAKRAESDVAAMSSEGEAAKPRRKLVSKGELRGEREKNRRASMVSTTSSLKDPSSPRDPKLDDHPEKPKGEPLSEKYHDRTKALKRDESRDRLSVSGDNSSKRHRSSVTPPHSSTGDKEEGEAPVKRRRLDVEGKERRPKSTASPDDPHRTPRDGPPRSKSSLRDHDDSDRRPTKAKADADGHRRESGKSSNSDKSSIHVKSEDFDIEMPDASDVKDTVEAEPRIKKERDDEKRRLEEKERRREEKRQEERKRREAEAEETHKKEEARQREREAEEKKREAEQKKREAEQKQREREAEEKRLKEEEVARQREEQERKRKAELEKKRQEEEERQRREAEEKKQREREEEERRLREEEEKKRREEEESKRKEEEARKQREEKERLRKERIEREAAEEAKRVREEEERQERERKERLEREEMERKRAAKEAEQRRILEEQERLRLAKLPPLLRWLDACPNPKTAEYAAKFKHMQGVRFDTIQPQANGTASGREQWVLNIHAALLLGEKDLSLSRYTAWEHVPVSDLAKKVIWRLESDWYALLKENFYELGTGLSDYYGEGEDPFKMSFRLKEKLRGEAREKFLKMDMFFVKVSDLMSTAQDVPHLRDLKMSVEYRELPDNEGQLYGWQVPQKWKQDPDADRFLGFAPRNKYYINGVMVEEQMPGLSATSSTPFPEKRVPRKGLQQVFPGDPDYARVCKEQGLDFLLNGTKTPTMPNGGHLSPRSQSNAAEAMAETVNDTQPAASATAPVLPEPRHVPNGVNGVSAPSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGP4</accession>
    <name>A0AAD8UGP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3 14">2.4.1.258</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dol-P-Man-dependent alpha(1-3)-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_755610</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyltransferase ALG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3 14"/>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361009.1">
        <property type="nucleotide sequence ID" value="XM_060514635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGP4"/>
    <dbReference type="GeneID" id="85398533"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU364047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1718009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="48390" checksum="C5D6BEF24EB2709A" modified="2024-05-29" version="1">MAEPAPPIYVQASRFVLDVANGRHALSKAIPPVLLALDAVLCGLIIWKIPYTEIDWVAYMEQISQYVSGERDYTKIKGGTGPLVYPAAHVYTYTGLYYLTDEGKDIFLAQQLFAILYLATLAVVMACYWQAKVPPYIFPLLILSKRLHSVFVLRCFNDCFATLFLWLAIFFFQKRLWTPGAILYSWGLGIKMSLLLVLPAVGIVLFLGRGFGGSLRAAWLMAQVQIVIGIPFVSNNAKGYLGRAFELSRQFFFKWTVNWRFVGEETFLSKPFSIALLGLHATALLIFAFTRWLNPTQRPLSSLLPAMLRGKSPFSALEEAQVANRVTPRYILTTILSANVMGLLFARSLHYQFYAYLAWSTPYLLWRSDLPFYVVYILWAAQEWAWNVYPSTDLSSEVVVGVMAVTVAATWFGTADEGAPVEKPESKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH84</accession>
    <name>A0AAD8UH84_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UbiD family decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_42325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360635.1">
        <property type="nucleotide sequence ID" value="XM_060502992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH84"/>
    <dbReference type="GeneID" id="85386891"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50077" checksum="FCEA31E1AD81D593" modified="2024-05-29" version="1">MDPDVCRNCGHSGKHIDFADARCAITERDDAERDKLQADAALARARDICETSLSLMKRQMQELEDANEAIDALRAALAAAEDRRERVRRDLGTHGDVCLLARSNLEAAEEMAISAAGRYFEAGRAVTALEDREHLRKQSPSIHVEEAPPLPMTVPMEEDDDAEEEAREKEDRRWKRSNERFCKWLRQSEAQRQIMKSSWTKLRVAERLAGESVNVDVDVDVDVDAVDDEEDEETARRKRVQAWTAARRLTDQLPPEEDPTMETEYLESEPTDSAETTEESSEPLVLAPAPTSAPTSSAHKTGVSKRTPALRTRAKTGRAATTATAPAPQAPQTVPPSPVKGRNLRTARRVESQTRSEPTRPTTATTTATKRVKREPRTTSAVVMGKTGTTTAPSSDGAAAGRPAARTRARTGKTPAAPTVAATETPAATRPQRATRRRSVRAQPYPQPGAQPRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHY6</accession>
    <name>A0AAD8UHY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_631699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361669.1">
        <property type="nucleotide sequence ID" value="XM_060508918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHY6"/>
    <dbReference type="GeneID" id="85392817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="677"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="719" mass="80810" checksum="5E6AF9A5BE58878E" modified="2024-05-29" version="1">MPKPRTKRQAIRDERKKKRREVDEENYEANKEGRSSKRRRVEDEEQDGEQQPAFDDAANDQEQSFRGNGPEVEFFGMLADEEQEYFRRADELLALNQFPSSEERDVFLQNVYKEARGKELKLASSQSLSRLMERLIILSNTRQKKQIFNAFATHFLSLVQHRFASHCCEKLFLESAPVVTQELGGIVPEPKADDEMDTEENGEPAPENTMEDLFLMTLDEFEQHMGFLLTDRFGSHTLRVLLVVLSGRPLDDAATKSMLKSKKKEYISVQGATATADELTHQLRAVPESFTMATKKIIQDAVSGMDFTALRVLAKHPTGNPLLQLLLELDISLNHKSDKESAASTKDTLLYRLLPDAPQSLSDESSQAADFVNSMVYDQIGSRLLETLLTNCPGKIFKALSRNFFGERVATYVRNDIASYPALRVLNRASKDDLVEAVKKIIPAVPLLVTKARYNVLKTLFERCEARGAYEEKSALTRALTDALGSNPRDVVPKLCHLVEEEPAAEDKKFQQDGPQNKTAVANHGCQLVIAMLKTSGNPVKVAQKSLLATPPDLLVKLATTSMASMTVLTTALATPAAPQNEFFHKALVGALAPHAAELAQSQFGHNIVLAIIDVPSRGTDRSIPFHVKQTIIGALAEHERALRDSWMGRSVWRTWKGDMWKTRRSDWVKWAKEVDGPAEETKLKPWERRKLDQQKGLQPRPAAAPVREKVEVEEQQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI18</accession>
    <name>A0AAD8UI18_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_578076</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364722.1">
        <property type="nucleotide sequence ID" value="XM_060505083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI18"/>
    <dbReference type="GeneID" id="85388982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="377"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="529"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="709"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="709"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="788" mass="89039" checksum="7BC35E5E411D82CD" modified="2024-05-29" version="1">MATPTNHPVTNPREGVTYLTEDEITSFLDDLDHNGDGYIDYAEVEAKLDAAHDELAPGGQVKPHHVISRHTSPEKPNQSPSSSDENRLRHEFLRSIMGLTGSEPGNISNPTASADDTTRTHRIPRAAFAARVREWKIPSLKQDVDSETSQRNFIQHLRLSRRLRAYWAVHGPEIAFLALVASSLIAFGVWQCVKYATTPRYRAAFGWGVVLAKTCAGMLYPTFFFLILSMSRYFSTMLRRSYRVSRFVNWDLSQSFHIKISCLALALATLHAIGHLTGSFYHGSRPENQDAVAAVLGLDAVPRPYVEYVRSLPGFTGLTALGLFYLLALLSMPAVRRWNYEVFQLAHLLMYPIIGLMMAHGTAALLQWPMFGYFLAVPTLLILVERVVRVGTGFHRIRATLTVLDGETVEVAATIPSERMWKYRAGQYVFLQVPAISAFQWHPFTVSICKGREFRLHIKTYGNWTKRLRNLGGKGEGGADAATEIDVGINGPFGAPAQRFYDFNHTIIVGSGIGVTPFSGILADLQARDDEEHGGPTHSHQHRNHQHRHDSETTVVTEKKETNERKGSESTMAAAATEAPDGNDPTKPPNPSEAFTFAPDYRRVDFHWTVRDRNYLLWIADLLNSVSRSQDWHRRHEGPSQHLDIRIATHVTQKRRDIVTHVYRWLLEMHRTEEHPESPLTGLLNPTHFGRPDFDAILDRHYEDMRRFHGNHRSENRDARADDRGSTRGASGERRDVEEEDEELKVGVFYCGAPVVGEILADKCRQLTVRGRHDGSKIEYHFMIEVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIA8</accession>
    <name>A0AAD8UIA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_584051</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362046.1">
        <property type="nucleotide sequence ID" value="XM_060505721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIA8"/>
    <dbReference type="GeneID" id="85389620"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="23207" checksum="65C7FAC3A59F30FD" modified="2024-05-29" version="1">MSLINIQSAGQWQGILSGNNVVIADFYADWCGPCKQIAPHVERLAKEHSKPNKVAFCKINVDSQSTIARTHGVSAMPTFIIFHGGQAIETIKGANPPALTQAIQNALKLPDKGGRSAASFKTPGRTLGGDKPARASLQRPFAWHYRDILSNIITFIGLYLVSLFAIDPHKAAEMSQFNRVNPPPPTVKSTKSAGPGTRQPPRGPAFKTLADLGGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIN5</accession>
    <name>A0AAD8UIN5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_578425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364666.1">
        <property type="nucleotide sequence ID" value="XM_060505120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIN5"/>
    <dbReference type="GeneID" id="85389019"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="115"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="56982" checksum="F1B7A4DBF6758E74" modified="2024-05-29" version="1">MPPTTRAQAHRQSLSDITTSDYYDDDDDDGGYEDDDGGGPSSSEPESDSDSSLVDDDDHSVIRSPSKLVYKLDMLSHDARLRVREAFKDPPRLSLQYCRLRDDVYAFQMTELVPRSIRIGSPDSPFATPRCSCREQQQKAGSPCKHLLWLLDQLVKQTLYDHDPTSPLTMTADGYPEEIGDPFSDISAFHLDVLADGLRCDVVTPDSEEDSENTDSDEAEEEGQEQEKQQYPNSHRVDEAREMLSAVMSSSPPEDYRPDLFSDPPSTGKKPVKRRDLEGTIFRMLLANNEFFHYFLSQMRSTDPVNDRFRKLSQRVDRVLRELDSYATTTNTSSSEGGSAEGPRDVAWAARHINGVIGLVRTSIFKRDRPLEPQERTSAARTLVHILAAVVERNRDFVPPTSTTRPAAIARRDKNLFLRLVGDRDEDFVLGVLSLLPPDAAAPFLHSLEDILDQLGINGAPTTYVEKFRSLISRLRRPGGSGLAITSSSGAGSKRHGQSQGHDRGPKRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJN5</accession>
    <name>A0AAD8UJN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_698176</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365637.1">
        <property type="nucleotide sequence ID" value="XM_060511392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJN5"/>
    <dbReference type="GeneID" id="85395290"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF13">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="38606" checksum="79658A25B863E582" modified="2024-05-29" version="1">MEDGKYVDGSYYFYAPNKAAPTFFAVAFAASGILHFWQSYHYKFFKVTALFSFCCLLFTAGFAVRTYGAWHYDDLNIFIASVCLIYAAPPLLELANYNILGRVLYYAPYASPLHPGRVLTTFAFFSSIVEALNGWGASYSANQSLTQRELETGHALIKTSLLLQIFVLASFVALAIVFHRRCAAAGVASVRGVTGPMVTLYVSVGLISARTLFRVVEYFSLAQVRFDAQTKEGDIPPAIRYEWFFYVFEASLMLANVCMFNVRHPRRYLPERYTVYLAPDGVTEVEGPGWKDPRAFWVTVLDPFDVRGLIKGRDRGMERFWERERGGRGGGDGGVEEGVEGKGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJV7</accession>
    <name>A0AAD8UJV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_582399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362796.1">
        <property type="nucleotide sequence ID" value="XM_060505551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJV7"/>
    <dbReference type="GeneID" id="85389450"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34861" checksum="DD957DCD971526E3" modified="2024-05-29" version="1">MEPRQVEALDDEDDWTGVASAAERRRRQNRVHQRAYRRSIPQPSSSNVLSRQKRHLKRIALNSASTSASAEPQAETSLVPDASLNARRPMTLSRMQEMYGIYYLLRCAGIRENVVEFLQRASSNWNLRLPTPRDLPALTRLNAFDALARNALVLGIPVELIESDEGNSLFIHQGPARPGSSEVLPPHLSPTALQRTVKHHPWLDLFPIPKMRDNILRGIRAGEIDEDELCNALVCDLLDLDSPSKSSLVIWGDAWDLNGWELGPEFFRRWGGLVQGCPEVLVATNYWRQKRGVGKIREINSGSSPAFNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJZ8</accession>
    <name>A0AAD8UJZ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alcohol dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="9">1.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_753784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a primary alcohol + NADP(+) = an aldehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15937"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:15938"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:15939"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.2" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363209.1">
        <property type="nucleotide sequence ID" value="XM_060514394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJZ8"/>
    <dbReference type="GeneID" id="85398292"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008106">
        <property type="term" value="F:alcohol dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000158">
        <property type="entry name" value="Zinc-binding alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="16"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="362" mass="38904" checksum="13B38E0A62246F1F" modified="2024-05-29" version="1">MSDIKFEGWLGHSPDSVNGKMEWGAFEPKKWTEDDVDIEISHCGICGSDLHMLRSGWAETPYPCCVGHEIVGKAVRVGKNVKHVSVGDRVGVGAQARSCMKSDCPECSIGRENYCGRANISTYGSVYPDGEGKAMGGYADYNRTNGHFVIKIPDGIPSEDAAPMLCGGITVFSPLKENGCGPGKTVGVVGVGGLGHFAVLFAKALGADKVIGISRKATKKDEVLKLGADEYIATDDDKDWSKTNARSIDLIISTVSSEKMPLQQYLRLLKVYGTFIQVGAPDGGNLPPINAFTLLASGIKVGGSGIGSPSDIKEMLELAVEKKVKPWVQKRSLKDANKAIVDMEQGHARYRYVLVNEKHAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKG1</accession>
    <name>A0AAD8UKG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366012.1">
        <property type="nucleotide sequence ID" value="XM_060504802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKG1"/>
    <dbReference type="GeneID" id="85388701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="84"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="380" mass="42802" checksum="6D3F926D29FAB873" modified="2024-05-29" version="1">MESRSHLSLAELNAAALDHFVYQPVSKSMISYLAGAAYNVISCDSALMPPASAEAQRQQQLPPTPPRTPEPRAVRTEDADLPTLEAFITQLVVSSNVQVPTLMSTLVYLTRLKSRLQPMARGLRCTTHRIFLAALILTAKYLNDSSPKNKHWATYSHVNNDFSNFGFSRTEVNLMEKQLLFLLDWELRISEEDLYRELDPFLAPIRAEIEAKHARRIARRRKQEEEMRRRHEEMMYNTYPSPPSSRASSRSRLESPDHARTYSGSSITPPGLCYSSSYGSSVSSYAPSVASSRSQSRATTPLDNPADEPYMYVPNGSLYESPVEVHIEQPASTLPKRKPLLPYEISTEELRDMQDGTKAKRARMGRGMWGRVFGGAVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKJ5</accession>
    <name>A0AAD8UKJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_318743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365008.1">
        <property type="nucleotide sequence ID" value="XM_060502357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKJ5"/>
    <dbReference type="GeneID" id="85386256"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="25458" checksum="326E497EE17FF550" modified="2024-05-29" version="1">MVRAPVTGEYPQDVAGEVPVNMRCSYPMRALPHHRHHEDGKPRLPNAHSRYPIPRSRPSAASQCSKSEVPMRSRSNDETIQPHQVSTGRKQVQGIKPVFCEFLTMLTAGDRRPPPPQGNGRGTAAGPEGRYSCAQRMTRNDLDRWQRFCSIFLSRVPYRFSPPPRRTRGIDHIWAHYGGKAKLGGKSGRWVGAAPKGNTGKVDSVRTTSGKTTVPEHWDCVTGKSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKL5</accession>
    <name>A0AAD8UKL5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_720787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363333.1">
        <property type="nucleotide sequence ID" value="XM_060512303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKL5"/>
    <dbReference type="GeneID" id="85396201"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="373" mass="40556" checksum="0150D64526776B64" modified="2024-05-29" version="1">MSEEHPQPTGSAPTTKTLTARCYCKAVHFTLTLPTSSLPLKVHLCHCSICRYTHGTLCIFHAPLPSGVSPSFVAPSSLSSSLTAYRHATASSTRYFCSTCSCHIGDVGVDDDEWVISTSIFDANQNDVPAVWDIRSHVNTASAPGGGLYEWLPAVNGKEMNIWNPKKDESEAATTTHGREVGVDGEEVLRAQCHCGGVSFTISRPKAFMLEDKAYEAWLSPVDSRKWPACVDACDDCRLQTGVHAIAWVCIPETCIAPSVPEDLQLGGTAKTFKSSENVWRSFCGTCGASVMAYFGVNGRRQKNGERLVNLAAGILRAPEGCLAEEWVTWRTGRVAWAESGMRYDAGVTEELGEGMARWGRERHGEAWGFNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKS2</accession>
    <name>A0AAD8UKS2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_580219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363795.1">
        <property type="nucleotide sequence ID" value="XM_060505328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKS2"/>
    <dbReference type="GeneID" id="85389227"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF1">
        <property type="entry name" value="CONSERVED FUNGAL PROTEIN (AFU_ORTHOLOGUE AFUA_1G14230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042018570" evidence="1">
        <location>
            <begin position="18"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="27739" checksum="746C305C685FCDC4" modified="2024-05-29" version="1">MRCSTLLVPALASLALAAPTYPTLNLQAALPGSIEQISEYFNMLATKVQATKYLSTAPVCDLSTAKLPQAATETLGKPRDGLTLMHIAIGRGTQNYTCDTSNSTAVPIATGAVATLFNASCVGSLYPDLLDKLPVVAMDFNLTEEETNRRLGPSNLAISGHHLFTGKGVPLFMLENDGASVGDSYCAKNASMPAPLTAQSGQHGEAAVPWLRLRTVEPSTGDVQEVYRIHTVGGSAPASCQGQAATIEVQYATQYWFFSGPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL38</accession>
    <name>A0AAD8UL38_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_697502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365926.1">
        <property type="nucleotide sequence ID" value="XM_060511384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL38"/>
    <dbReference type="GeneID" id="85395282"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="508"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="539"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="611"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="164"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="772" mass="86732" checksum="D0EFB8665021D2B4" modified="2024-05-29" version="1">MRSHTPSGDPPGRRASVTNRFRNSTGGSALPRPHTSLRESRTFRATQPTYNLFTGGDANSRPGSRASLAAPDSVRASSHESSKENMAPPDAAEYESQRQVIEELKAELGTLRYTISTFEQEKQMADARHNAELEDQRRRAQADFTAKQAAESEKSQAARQLENTQKELSDLRENVAEEKTALEKRARDAEEEARLLQEQLEDLSSSKDEAARINERKTIDLEMQLQAAQKSTQELEQESQAREAALQQIQSQLVDKDNHVADLESEVLRLKAQTGDADTMAIIKRELSEQVAHIRSLEATNREQLSELKHLRQIHRAVEVVEEEKRSLQRKLEAARSLETELAEANIQRQRLEDERIAWTGYLASTDNGSGDLEFDSPEAVARALVEQRYENAAQLDKMGSLQAELAAQESSIKSCQEEITTLKSQLADAKSAASAPQNIDKTRLRTERQRVLAVKEVEYLRAQLKTFDAEDEAFQPEAVDETRARRIQELEDLVDKYRSEVQALHTEMSSMEAGKPPTAADPTPAAGTKRPRDENDDLSAAQEQLGLLTRKNRKLQDQLAAVQTQHALTQKELAVTQDQLKALKTQSKTRVLSLRSNPTSDYEAIKVAKLKALEQENTDLLAQLNDNENVDLVPRSQLDAADRLVEEARAETASAQKSAKRLKEVWSKKSLEFKEAIFSTLGWTVMFMPNGKMRVESTFYPSQTDEYENSIVFDGEKGTMKVGGGPRSAFARRIGDQIGFWVREKGCIPGFLAALTLEFYEEYSRNQMQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULS6</accession>
    <name>A0AAD8ULS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_386648</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363741.1">
        <property type="nucleotide sequence ID" value="XM_060502748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULS6"/>
    <dbReference type="GeneID" id="85386647"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="8"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="45479" checksum="DC0E252600E7689B" modified="2024-05-29" version="1">MLRLLPPHTIIKMPALSPTMTAGNIGSWQKKAGDSIAPGDVLVEIETDKAQMDFEFQEEGVIAKLLKESGEKDIPVGNPIAVLVEEGTDVSAFEGFSAADAGGESKPAPKEEPKKESESKPAPTPEPENSSDDFNKPAGKLENALEREPNASFTAVRLAKEKGINIRDVKGSGKGGKITEEDVKKAVSSPVVAAPGASYEDVPISGMRKTIASRLVESTQTNPHFFVSSSISVSKLLKLRQALNASSDGKYKLSVNDFLIKAIGVASKKVPQANSSWLGDVIRQHNTVDVSVAVSTPTGLITPIVTGVEARGLEGISSEVKKLAKLARDGKLKPEQYQGGSISISNMGMNDAVDSFTAIINPPQSTILAIGTTKKVAVPALSEDGTTGVEFDDQITITGSFDHKVVDGAVGAEFLKELKKVLENPLELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM14</accession>
    <name>A0AAD8UM14_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_652923</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363604.1">
        <property type="nucleotide sequence ID" value="XM_060510572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM14"/>
    <dbReference type="GeneID" id="85394471"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000024">
        <property type="entry name" value="Sulfate permease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="573"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="720"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="810" mass="88952" checksum="88BC745251EC3BB9" modified="2024-05-29" version="1">MSSKVGRTLAKGLGIDVDARYRNEPTEAVQSAAASFRSVEQYEEREPTVAEFLYEHRPTVHGAVNYIKSLFPFWSWIFHYNATWLLGDIIAADYSFKGVTVGFVVIPQGMAYALLAQLTPEYGLYTSFVGFILYWAFATSKDITIGTVAVMSQLVGNIVLRVKDSHPQYDGPQIAQALAVISGAVLLFIGLVRLGWIVEFIPLVAITSFMTGAAISIAAGQVPALLGLQGVNTRNPTYEVIIDFLKALPTARLDAAMGLTALFLLYSIRSFCNFMSNKQPHRKKFWFFMSTLRMAFVILLYVLISWLVNRHVNWDAKKAKFKILGKVPSGFQHTGAPKIDTELLGAVAPDLPVTIIVLIIEHIAISKSFGRVNNYVINPSQELVAVGFTNLFGPFLGAYPATGSFSRTAIKSKAGVRTPLAGIFTAVIVLLALYALTSVFFYIPMATLAGLIIHAVGDLITPPKVVYQFWEVSPLEVFIFFAGVLLTIFTNIENGIYLTMCASAALLLVRLAKAKGHFLGRVKVYRATKDTAGKGVPFNERGEAIDVPARESYIPLEKDDGSNPNIDVQTPYPGVFVYRFGEGFNYTNQAHYMDALVAYVQKHARRTILDRYEKLGDRPWNDPGPRRGAKIDLDDTRPIVRAVILDCSAVNNIDVTSIQGLIDVRNALDHYAEPEVVEWHFANVNNRWTRRALAAAGFGFPSVKDEGNFGRWKPIYSFAPVDSGSGHEPRVTSQRSRDEEEEDVISPTSKGHDGAARVVGRGDGKLAAVQGMNRPFFHIDVAAAVESAILNAESKSGGQRSSAESVLKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM49</accession>
    <name>A0AAD8UM49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_650133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366897.1">
        <property type="nucleotide sequence ID" value="XM_060510348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM49"/>
    <dbReference type="GeneID" id="85394247"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="140" mass="17130" checksum="D9CA25238381AC2E" modified="2024-05-29" version="1">MSAWLDVLTLNGTDLLDYGRKERRLHDEGLTTTRRKWHRTLAVNYRPPYLTLRLRLLGITYGKSKDDWMFWWVTEYEHYAGEFWAMVHRVDLDVNVPGGWVDERDRYYYEYQEEEVAREWLDEELMPMIWSEYCEIKAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMC4</accession>
    <name>A0AAD8UMC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_617653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366073.1">
        <property type="nucleotide sequence ID" value="XM_060508036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMC4"/>
    <dbReference type="GeneID" id="85391935"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="133" mass="15658" checksum="62CA94675DA2785F" modified="2024-05-29" version="1">MRKANNLGREKWWAGVFVLYYCRHDEMPGRGPARRLRTWWKGDWDTAKTEREMCRGRQLVWCLFPPRCEFWTLQAWLGRGGRRPYGAIDACLSSYVVLYGKRTLAKPGATTPRGQIVSQRRCTKNIGWVHYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMD6</accession>
    <name>A0AAD8UMD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_780886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363784.1">
        <property type="nucleotide sequence ID" value="XM_060515535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMD6"/>
    <dbReference type="GeneID" id="85399433"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="32257" checksum="D9C731FC2662928C" modified="2024-05-29" version="1">MATMTAGLMPIATPALLTSLRNQPHVPKNAWYFIAATTLTILNRPDEIPQVYNHVMKHGLGPDDVKPGPEEQLTILRKLREALVKASAVGGLPKTINSLMELKKVTPEHLLDEPQGANDTLSSSPTARHVDIHHTPSSKILQRGQGFWDNIYGKISRRVMSQMDRSGTEDLGLTARLMYGYILSNTNVLSPVETSYVLIAGLIPQDVNPQLKGHLKGALNGGASAEEVRAVRGIVMDICKASGMSQLGEGVPGGWGWRSEVATSLVPPQAYQLSAWGRDTWLLRSAYAVQPSPISKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMT0</accession>
    <name>A0AAD8UMT0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase A4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_621435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364875.1">
        <property type="nucleotide sequence ID" value="XM_060508264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMT0"/>
    <dbReference type="GeneID" id="85392163"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042131864" evidence="2">
        <location>
            <begin position="17"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="27430" checksum="AFF1FBE26B1A39D0" modified="2024-05-29" version="1">MKFSAFVLAAAGIVAAAPGTQLVQRNYSPLTPRSSRSRYNSSPIKRLSTEAVETLEKTSGVKNVDYSSNWAGAVKIGTGYNHVTGTITVPEVSGSSGAAASAWVGIDGDTCQTAILQTGISFYADGTFDAWYEWIPDYAYSFSGFSVSVGDQIKMTVDASSKTKGVATLQNLTTGKTVTHTFTSTPSTLCETNAEWIVEAFEENGSQVTLADFGTVVFTGAAASGSSGSTTPAGADIIDISPNSGRTIEASASVSGSTVTVKYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UND3</accession>
    <name>A0AAD8UND3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_695307</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367081.1">
        <property type="nucleotide sequence ID" value="XM_060511355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UND3"/>
    <dbReference type="GeneID" id="85395253"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF79">
        <property type="entry name" value="LACTOSE PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="61"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="60360" checksum="F1B64D87588674F9" modified="2024-05-29" version="1">MAPREDVDHTVIFHDDVAQANKIGVAVEEVAATRISEADMMRKSAEALTLKSKTGLYIFGYMLVMGCNQAGFGIDWGVISGINSNDRWHDFYGFGNAGVIISTINALMQIGGFLGAPFLSCADVLGRRGVNFLGNALVIIAAIMQAMAPNLACLFVGRLVLGFGTALCTAPQYVAELAPVHLRGRLVGVFGACFQVGSLMMIGIMMGLTNWDSDWQWRMAFFIQAIFPLFVCVTIYFLCPESPRFLYMRGKKEEARRVVARYMTTDNDINHEIVDLMILQIEESIETTKAGFRATWDFRVFFTKAVWFRTVVLAVYAVFQQWNGGGIIGYYLAPALDTIGITSQLDQLGISLGSTAIYFVFTLFGSYIIDYFRRRTLIFAGLISMICAQIAVTITSWQYNLSEQKTTAILTVVWIYLFQVCSATFIATMHNLYPVELLSLPLRAKGMGLFAMFQAIAAVVHNYGIGIGVGKVGYKIWAVYIVYNFIQIIISYYVFPETSKLNLEEIDTIFETPGGKPVKLSIKIADAKREKAKLDRQNGVSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNM5</accession>
    <name>A0AAD8UNM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_578695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364444.1">
        <property type="nucleotide sequence ID" value="XM_060505156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNM5"/>
    <dbReference type="GeneID" id="85389055"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="666" mass="74103" checksum="6DE70569C36998E1" modified="2024-05-29" version="1" fragment="single">RQRVVSQFNVVRTSLIDNNTTPLQVGNGNFAFNVDNTGMQTFLPFNTLSSWAWHNDSLPTNGFKLSDYTGVPMLTHGRNVSYDIPDSKLPQVSQWLIGNPNRINLGRIGLKYKGETLSAAAIADPRQELDLWSGIITSTFKVDGNAVKVVTQGDFATDAVTFQVDSDLVLSGDLNIELDLPYPPIHTTKYKYEVFAGVYDFPLNHTTRIINSCGRSDLAHIYHDLQETSYFVNLRWPHEAPLNLSRDEPEGSDKINAHRYTLALVGGTNQTSTSLTFTADFSPQKQDPRPPADVQEESIAEWHDYWNEGGFVDLTLSSNPNATELQRRIVLSQYHVRVNSAASGQSPQESGLMNNGWYGKFHMEMVIWHNAHWVTWGRKKYFDNIFPEIYETLLPSSLARAKLQGWEGARWPKMTELETGVSSPGGINGLLLWQQPHPMYLAELAYQSSPSDDTLKQWDAVLTATADYMASYAWKNESSGHYDLGPPLGHTIPEKWTEVAENLAPPPQVDGLYAVYEGLNSTWWQDPALNGDPRSLIMMQGILPDTPAVDPDVALKTADKVWEVWTDQKIRGWGRPVLAINSARIGNPERAIHHLTAYDYWKFDDAGYAIRGGDGGTPPPFMPGNAGFLYAVAYMAGGWQGSKGDAPGFPQGAGWVVKQEGLQKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNQ3</accession>
    <name>A0AAD8UNQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lin1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_613484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367201.1">
        <property type="nucleotide sequence ID" value="XM_060507763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNQ3"/>
    <dbReference type="GeneID" id="85391662"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="418"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="473" mass="52811" checksum="A657D58C500A117B" modified="2024-05-29" version="1">MASRHSAARPKRAGETFARTHHHDAEADDGHDSKKLKFDVRNPSALAPDAPEEDAILDADVIGGGGGATKRGAVNLDGYDSDSDNERNFKSRANEKHKGRKDGDADFFGQLDNYDAKDSGANGKGGKVNEDDDEDDDMFAADDDDGEKEGKAAQEGTKAAGKDKAVRFLDDAQIQGQELHSKSGGQIRLDDEESSDDEEDKELAMQEEGIDEEVGLGGLKRNAPKVEAFNMKDEQEEGRFDEDGNFIRKAVDPNAVHDKWLDGLSKKDLKKAADAHEKREAEARRLRMENDDILTTDLLKALIVRLERGETSLEALARLGKGQPKTRKIPKWKLKKQSKGGGEEAMDVDKEKDQLSPEQQKRKEAIEAITDAADKLLSRDHAEIYDEEREMLVREWQRETGEQWVEPAKDDADDDLSSRMWEFRWTDGRDNAEKQGPYDGPTMKAWQDAGYFGEGVEFRPVGDDSWTRVATFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNT5</accession>
    <name>A0AAD8UNT5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal STAND N-terminal Goodbye domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_719547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365028.1">
        <property type="nucleotide sequence ID" value="XM_060512190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNT5"/>
    <dbReference type="GeneID" id="85396088"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="506" mass="57430" checksum="398D11BBC8D9D245" modified="2024-05-29" version="1">MADYVGTFMKTHAGELDPSWQVSARDKVHERTKSFKTLISIFAQRTNRKDLARFDVEKDFQWEDVRVMASEAIEQDNAKTKMRHNPFRAAGRSFQRNASNLEMLVAFLPNGDFTGILCGALTFVFCIINCLDSLPDIVEETEEYVDIYDDDPRVWRAAEDLYLGILDGVESMLQWIDKSALERAFKVLTRPTTFGKNVEEETIKQNIEGSVAKFRNVVLMSQHKHINKSLKALKEQLNSQLKYADWVRDNPKAEKLVIKAFITLDELRASIGFDPKINQKDMVTSMIDAQKVCPPEMISHAMLALRDNKFTSWLQSNESQRLFIEGRMKLNSEQEAASPLTMLSCALAQLVARESERSIPLVYLCGQHNRQNDPHSGASGVLRCWNSLIAESLTPRDVDLSAINLSFIDGVRAQQLGVLCMLFRHLVMAATDKVVFVILDGALWLEVSRHVQGLGDVVLFLNNLVTVLNQQNYGVILKVLITHPSTSNHARRWLPKECVLEMDDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPA3</accession>
    <name>A0AAD8UPA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Fumarylacetoacetase</fullName>
            <ecNumber evidence="3 13">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_577827</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="3 13"/>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364956.1">
        <property type="nucleotide sequence ID" value="XM_060505058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPA3"/>
    <dbReference type="GeneID" id="85388957"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.230:FF:000001">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000009">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="15">
        <location>
            <begin position="19"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="14">
        <location>
            <begin position="136"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1724901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="432" mass="46924" checksum="751FE568B537611C" modified="2024-05-29" version="1">MSNTQSWVSVSPKSHFSLANIPFGIISTTSDQTHRPAIAIGDNALDLKAFAKAGGFHALPSIQDHVSVFSSTTLNDFAALGRKVHREVRTYLQSILAENTPHAGLLKDNADLRKTALIPFSEIQNHLPLAIGDYTDFYAGKNHAYNVGVLFRGPDNALQPNYVHLPVAYHGRASSVVVSGTPIRRPWGQILKDPKAEPKVPTLAPCQRLDIELEMGMFLCRENKLGEPVPVDQAEEHIFGYVLMNDWSARDIQAWEYVPLGPFTSKNLGTSISPWVVLADALDGAKTAGIENKTELQPYLRESKTNNVLGVDLEVDIITASGNKTTISRTNSKNLLWSWPQMIAHHTITGCNLRPGDLLGSGTISGTEPGTEGSILEQTQGGKQAVQLTGGEERKFLQDGDTLIIRGWSGQEGALVGFGEVSGKIEAALKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPC4</accession>
    <name>A0AAD8UPC4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Very long-chain fatty acid transport protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Very-long-chain acyl-CoA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_751711</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365519.1">
        <property type="nucleotide sequence ID" value="XM_060514091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPC4"/>
    <dbReference type="GeneID" id="85397989"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000019">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="13" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="21">
        <location>
            <begin position="62"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="22">
        <location>
            <begin position="504"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1725464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="631" mass="70496" checksum="28544C08F6E39E9B" modified="2024-05-29" version="1">MPVPLALALPAAAAAYSYINARISLWYDRKLLSCALPATLSALWRERTDRLNQFYILEQAAQNKSSANRTFIIFEGKTYTYRETYEQVLKYGTWLRERHGVKPKDIVAINFQNSDVFVFLWLGLWSIGAKPAFINYNLTGKPLAHCAKAAKTKLMLIDPNVAANVTEDVRSELSTVQFVVLDESLHREIDAVKPRRAPDSDRSESQYQNLAILIYTSGTTGMPKPAIVSWAKCIVGGVFTSRLTSNSPNDVFYTSMPLYHSSAALLGFGNTLEAGGTICIGRKFSTKVFWEEVRSSKATIIQYVGETCRYLLAATPQVDPVTGESLDKKHNVRVAFGNGLRPDVWNRFKERFGIDTIAEFYAATEGSFGTWNLSRNDFAKGAVGRNGTLYSLVMGLDVALAEMDENNEEPWRDRKTGLCRPAKAGEPGELMFRLSPDDLNRRFQGYYGNPDATKAKVLRNVFKKGDAWFRTGDVVRWDSEGRLYFTDRIGDTFRWKSENVSTQEVGEAVGSHPLVQEANVYGVELPNHDGRAGCAAVVLQGQPSEEVLRSIAQHVKQSLPKYALPIFLRVMPPEAMQTTGTNKQQKHGLRSQGVRPSGTDAAGEVYWLKNNTYEPFSGRDWDELNGGRVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQJ9</accession>
    <name>A0AAD8UQJ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_612613</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367708.1">
        <property type="nucleotide sequence ID" value="XM_060507718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQJ9"/>
    <dbReference type="GeneID" id="85391617"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF13">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN MOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="52484" checksum="5217E61AE77E1C60" modified="2024-05-29" version="1">MVLLAPLKRHSPATTNKVSNEDSNSDQLVSTVTRKRAKHTRTRLGCATCRFRHVRCGLERPSCHRCASTGRVCDFVVDSNNERRSSVLAKSAYISITPRPNPNDAIYQPAPQTGRWINFYQGHSAPEFAGYFDVEFWSTTILQLSYREQCVHQMLVAIGSLHESLKSGLVQNSDSNAVNLYKYAEAEYTIAVSLLNTHMTHRGWSALEITLVCSVLGIMFEWLRGGYQDAVRHLTSSFKILSTWLSHNAPSSTTSLGSPGGHLIRSQIKPIFHILVLQSRMLPIPPSVPPKVVQAPEQIIPEFSSVAHARNVQLDLLTYVLLVPPKVAGSKGRTHQVVAGPLRQWSDKFALFISQQPHLAADPCVKILKVWRIITEMITLSPFSPEPDSSHGLIMQLSTFLDNVESRKISVDIGAVAIFYHTAAYCRHPEMHRRAIALMKSAGGPWGHHVAIKAQQEYARLEDDDPKLGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URE0</accession>
    <name>A0AAD8URE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">C2H2 finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_650792</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366021.1">
        <property type="nucleotide sequence ID" value="XM_060510401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URE0"/>
    <dbReference type="GeneID" id="85394300"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="173"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="323"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="506"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="515"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="63027" checksum="9333C82BF8EC9C03" modified="2024-05-29" version="1">MASVDVAALGAVPANGGATAASHPYTCNTCSVAYRNIDLQRGHMKSDWHRYNLKRRVASLPPIASEVFNEKVLQARAVQTAEAEKALFERSCDACQKSYSSENAYQNHLTSQKHKVRVAAIARRKGGVADDASSVMSSTFSLGEPIAVDKESELDSEAEEEFTQVVEGLKKTNIHESHGERPSPVKRPSNPHLSAQGQRDDVNMNRDSESATPVQSKPEIAWTIKSCLFCNYESPSVSLNANHMERFHDMFIPEKQYLVDLDGLLQHLQERVHDGHQCLYCFKTKKTAFAVQTHMRDKGHCKIPYDTEEVQLDIGDFYDFRSTYSDGEDSDEEEEEADENGGAKLGLKRPTKLVGEDGEEVEEGGDDGWETDSSASSLDSDELTAFTADGKYEQFERLDKHPHHSTNDPRARHQADGWHSHAHKHTRAVFYDEYELHLPSGKAVGHRSHNRYFRQNLHNYPTEEERAERLAIEAGSGSGDEMDVDGREVATTGDRKTRNRAIARRDAAGMAGASDKQKRVVRQEEVRGRSTATRHQKRYDYGVSEKLNNQKNFYYRYQAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URY2</accession>
    <name>A0AAD8URY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_572591</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367365.1">
        <property type="nucleotide sequence ID" value="XM_060504530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URY2"/>
    <dbReference type="GeneID" id="85388429"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="291"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1727310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="385" mass="42058" checksum="3562E54C4A0F1897" modified="2024-05-29" version="1">MTEPVSPPSSPPADSVTPSTTNSHPPVTPENKRLSQVGGMSFAERRMSRRPSTAPTPIVEGDGLTRDVIHSLPGDTRNNNNRKSKTQADMAKRRSSYYEEAFQGDRESNVIKDRAYAEAIVMAELRTNVIINDEFSFITDFSYQLSVRYQRPVTSIVVNLQHGACMLFGGTFEPAYTMSIHALPLEVGVTKNKRNTALLQKHLHEALGVAPVRGFVKFVEVPAENMAVNSKTTASHIAEMTGEEEETIAERRGRNRKSISGKSMSALRHGSIVGGRKGSVFDFRRESVAPRKDLVMPPPHEITPPHSATDAPPIPPIPEAHANKTTAAVPDEKSDTPIKEVEKAPTNTSASLKKSKVAKRKSSFVTSLFSRSPRNTPAPMPTVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US11</accession>
    <name>A0AAD8US11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_617161</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366154.1">
        <property type="nucleotide sequence ID" value="XM_060508011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US11"/>
    <dbReference type="GeneID" id="85391910"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041898514" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="11">
        <location>
            <begin position="28"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1726099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="29425" checksum="67D029C0968739A1" modified="2024-05-29" version="1">MHASLKTFLALGLASVACAQHTKQDDEMGPAAFMWPADRVWSGDMDNQAPCGSKSGAANRTQFPLVGGKVALVAQDDYYNSKISISYQNEPTSNSDFTTIIEEQSVSDLNPGHTCVDVPNPPSSIAAGSNATLQIIYRADWDAPHNQTFYACADITYVEAANFNTRIPCFNATEPGEDDIAATASPSASSTNAASNSGSGSGSSGSKKLSGGAIAGIVIGAVAGVGLLIGAALFFYRKSQQKKRNSRLARMEENAKRSEHYNVGKDSTSQNSIKMNNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USD0</accession>
    <name>A0AAD8USD0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367064.1">
        <property type="nucleotide sequence ID" value="XM_060513903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USD0"/>
    <dbReference type="GeneID" id="85397801"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042001097" evidence="1">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="95" mass="10138" checksum="F15FC8DEE11EF9AC" modified="2024-05-29" version="1">MKATAILALLYLTPLGVSAWMCSCYKKSIPDLHAAYHFCQPGSGHKYCVNKATNVQACIMGAPITTANCASSYGSDWVAECEHYTGGCPPGMTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTH8</accession>
    <name>A0AAD8UTH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_767861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368250.1">
        <property type="nucleotide sequence ID" value="XM_060515293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTH8"/>
    <dbReference type="GeneID" id="85399191"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="67342" checksum="E284F76484B806BE" modified="2024-05-29" version="1">MTMDRSVRNKKEKSRSGCLVCKRRRVKCDEQEPSCQRCIRIGTECPGYKRPVRWSTKYEKTTVSGYNPTNLGSCKTTKSVQCIQGLSAVREHSTALSSEHLQDTPPHAETGDLDTIIVPGTLKSISTITPFQDCSGEVSALLHYYFSTICHVLSSFDSLHNPFRSEVPRLFSQSPLLLYCVLSMSAAHLYQNEESRVVVPLRLQTKAISYLSEQLPRPPHINESEVSVYSEPEVGRLVGADIGDDVLLGTILLGMTSAWHDVSSTGLMHLHGSRELFKTWMSSNHLDTTNQRRTMSVTQDFVVSSMVYWEAMSSFIVDQAPNALSYLDAFCYHHPPRSRQTRPCPWTGVGTITFIYLAKTATLFRKLRALSSLGLCGRGDGVQDTSYSDLLQHATILQEEISRLEDSAVLSVADSGDMFTPPGHLVAMEQCYRLAALLELYRAFPELVETSTAKDHARLDANGQINEKAEKVHRFAFRILQTMEEIPVTSGTVSTQLLPLIIAGSVLGLVSRENVAGEGTEFLGSAEQITRWREFVRMRTRWLYQLIRLKPVRHGLLILEEVWARLDGANATSRSNYLNPGRESCHWIDVMEEKGLETMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTK6</accession>
    <name>A0AAD8UTK6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EthD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_717632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367578.1">
        <property type="nucleotide sequence ID" value="XM_060511968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTK6"/>
    <dbReference type="GeneID" id="85395866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02118">
        <property type="entry name" value="EthD family reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40260">
        <property type="entry name" value="BLR8190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40260:SF2">
        <property type="entry name" value="BLR8190 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="2">
        <location>
            <begin position="20"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="11950" checksum="F29D8A1B7109EA97" modified="2024-05-29" version="1">MPATVSVLYPNEADAKYNIDYYVESHMPMAAATWKSAGVKSWKVTKYSASPDGKQPKYAFAGILTFDSIESIHKALASPDTAKVMQDVPNYSNKEPVFLIGEDAKEATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU08</accession>
    <name>A0AAD8UU08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_664776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368550.1">
        <property type="nucleotide sequence ID" value="XM_060511082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU08"/>
    <dbReference type="GeneID" id="85394981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="14"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="38879" checksum="E63651D34F072EEF" modified="2024-05-29" version="1">MSYPEKFTGFCTAGPSSWNKFTKETLTPKPFEDHDIDVQIECCGVCGSDVHTITGGWGEYEGPLCVGHEVVGKAVAVGKNVKEIKVGDRVGVGAQVWACLKCEQCKNQNENYCPHLVDTYNAKYEDGSQAHGGFASHIRAHEYFTFKIPDAIKSENAGPLMCAGLTTYSPLVRGGVGPGSVVAIVGIGGLGHLGLQWAKALGAEVYAVTHSPDKAEDCKKLGAKEVIDTNKKDWAKPYAFKFDFMLNCSDMTNEFDLQTYLSTLKVGGHFHMVGLPDKPLPQFPAGLFASNSAKMSGSHIGNNQEMNALLKLAAEKGIAPWVETIDISEAGCKEAVERVKANKVHYRFTLVGHQKAFGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUS0</accession>
    <name>A0AAD8UUS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_667851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366725.1">
        <property type="nucleotide sequence ID" value="XM_060511102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUS0"/>
    <dbReference type="GeneID" id="85395001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF1">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE STHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="22"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="38655" checksum="22176C0C90A20B90" modified="2024-05-29" version="1">MGSLSHQNFVPPTTQKAIVVNGKDEVVIWDEAPCPKIPADQVMVRVEAVGLNPSDTKMRGAFATKFGILGADFAGTVVAVGDDVDNITVGDRVFGAQNEMYGTTPERGAFCEYAVTRGKMWTKVPEFWSTEAAASLPVGVSTAGIAMKLLGLPLPGRGAAKPAHVLVYGASTATATIAMQMLKLSGLDPIAICSPKNFDLARRNQAVEVFDRNDRDLAGKIKTYTKGNLKYALDCITTVESTAFCYAAIGRGGGKYVSLDPWQQHAATRKVVTADFTVGPRIFGEGCTWPEPYKSDPSEELRVFGVSVWETVEKLINEGNLQHHPLRVLDGGFEAILAGMEMVRNKVLSGEKVVVRMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUU8</accession>
    <name>A0AAD8UUU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_649043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368253.1">
        <property type="nucleotide sequence ID" value="XM_060510239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUU8"/>
    <dbReference type="GeneID" id="85394138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="192"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="473" mass="54350" checksum="6B72A9D9791090B2" modified="2024-05-29" version="1">MALLALAKSECSTQNSKKIQDAFEQFEQALYPSDAKLFRGLSLEDVQNAARAVEREQSERRALRNTRRLEPFFEALKTLGVVLEPLCQGIPFLCFAWAPIKLSIVMFIRLHADLAILSRLATNRDLVDREAASFEIVEAMDERERLMREAAKRENERLDEYARQVFEWLQLGVCDREQEDLLNDFQEARVPETCEWLMRHSEVMTWLDEEDKRQVLWLKGKPGSGKSTLVSYLMQMAPTSSRSVLMCCMSSELLRKGEQNPACTILKVFCAKMLRLNRRLLPYIYEEHVRFNSTLPLTKVRQITKLLVDSLGHVFLVVDGIDEYLDGDQVRIFDELSRLLKPPSDTADGLGAPEPADGTRMSSVKLFISSRETRPILREIKKRWKQPAVINLTKDKEHALVSEDISRFAKVKLRALHDEFDEDVLQSILESLMSKADGMFLWVHLIMGFLQDQASVEDLRSTIDRLPRGLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXC7</accession>
    <name>A0AAD8UXC7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_610324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368180.1">
        <property type="nucleotide sequence ID" value="XM_060507582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXC7"/>
    <dbReference type="GeneID" id="85391481"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041955485" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8223" checksum="AC6FDEE0F72E7E17" modified="2024-05-29" version="1">MKCGLVLFLVSLGWQLPDAVDCITNPRHLLILFDHSPHLTQLPKLWSWTRWTKRTPLPTAYPPLPPILPSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXF9</accession>
    <name>A0AAD8UXF9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_570951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368270.1">
        <property type="nucleotide sequence ID" value="XM_060504358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXF9"/>
    <dbReference type="GeneID" id="85388257"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF30">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="219"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="409" mass="43841" checksum="8B4D441B1CA1E1A2" modified="2024-05-29" version="1">MTLSSVLSFAAASRIQQPIGVEFSPPTLHSPSSAAPSWRDDLISLHRSLIEIPSISGNESAAGKFLVDYLTGRGYVSSLQFLPPRNNNTEETPRFNVLAWKTNQRQPTPRIVVTSHYDVVPPHIPYGISDDKITPDTRISGRGSVDAKASVAAQIIALEDLFEAGKVNPEDAMLLFVIGEEDTGDGMRFFSDSLQAADPPIQFESVIFGEPTENKLACGHKGGVFCDISAKGVAGHSGYPWLGKSANEVMIKALARIITTDLGSTDKWGNTTVNVGQFNGGVAQNVIPASALARIAVRVAIGPERDGGNIVKERIRKILDETDAESLELTCTHGYGVVEANCDVDGFDTLVANYGTDIPNLKGSHTRYLYGPGTILAAHGRNENITVGELEESVGGYQKLILHALKDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXU4</accession>
    <name>A0AAD8UXU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_114712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368675.1">
        <property type="nucleotide sequence ID" value="XM_060501117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXU4"/>
    <dbReference type="GeneID" id="85385016"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="28695" checksum="E3BC4EC119176AA5" modified="2024-05-29" version="1">MSEANKWNPTAASTEQRTKQDTANRQTLDDLRELAAERELGTEYTEKSPGNPQRRRTQLNGLESVGDFLETPGGGPGSNQYSHTLTHTHTLEYWAYRHSRLSGHTFIQLRGAPVSLIGSPPLPQAEEEEEEEGEGEEEPRTNSCGYLTLVAKVPFGYGEPGEARKYLGFLHLTLSRRPPYPHYTKYVTDYLTPFTTHPSHLRLMRENPLFPPPPSPPHTLAILIPSRLITPLLVLSQNPSPTSTTYASELPQPPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Q4</accession>
    <name>A0AAD8X8Q4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sir2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_592966</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358177.1">
        <property type="nucleotide sequence ID" value="XM_060506587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Q4"/>
    <dbReference type="GeneID" id="85390486"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="375"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="446"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1707961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="55181" checksum="B76F846C337AE482" modified="2024-05-29" version="1">MGNEESTMLDDSVQPKTLESRSLEAIADYIKSGDVKKIAVMTGAGISTAAGIPDFRSPGTGLYANLARLNLPYAEAVFDISYFRKHPEPFYYLAKELYPGKFHPTVSHAFIALLAKKGLLQMNFTQNIDCLERRAGVPDDKIIEAHGSFATQRCIECKDTFPADRMEKHVQDENVPKCDSCGGLVKPDIVFFGEALPEAFRDNTHLPAMADLIVVMGTSLSVYPFAGLAEASKSGVPRLLLNRERVGQMGRRADDVVELGTCDAGVRKLAALLGWGDELEALWRGIVGEKEAERQLASAAGEGEDDLEEEIRRVAEGVDTALKLDDNKDDVKDKDAAEATKKTEEVGFPLRQDGGSDIEDAQKSIPEGVVQRMSKAIQGQGGEIGTDIKDDRGREGRTVNGSEGAPQDAKDFRIEAKKKIQLAAQGAATPLDEVAIVFDASAPVAEMKHEDPKSADLLSGVSRYEETSAPATSVNKESAVAKAESASASTTAQETSRSVEKEEKPSSGDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8X8</accession>
    <name>A0AAD8X8X8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Steroid monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_591304</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358854.1">
        <property type="nucleotide sequence ID" value="XM_060506422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8X8"/>
    <dbReference type="GeneID" id="85390321"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="12"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1710575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="61468" checksum="78FF09BDB73EBCD2" modified="2024-05-29" version="1">MEGQSANTLEADVIIIGAGFSGCYALFEIREAGFSAKVLERGDDFGGVWHFNRYPGARVDSDTPAYQFSLPRVWADFHFTERFPGSEEIRRYFRHVDATLDLRQDTIFDAQVDEAKYDTEAGRWRFRTSNGLRATSKYAIFACGSMNKPYMPPVPNQDLFDGPIIHPSAWPDNLSLTGKKIGIIGQGASGLQIVQELAQLDCELTVFVRNPCIAVPMHQRQLSYRESEEMKHYYDAIFAKAKFGSSSALPYNQNSDSLRCATETERNDLLERLWNRGGLGLTQSNYRDIVLDEKANACLYDFWVRKTRSRMTDPNKMDIVAPLQQFEWFGSTRVNLEINYYETLDQPNVKVVNLKETPIQSFDRQGILAGSSDVATHHDLDVVIMATGYDGVTGSLLDMNIHGKNGVRLKDAWKSGINTHLGMMIPDMPNAFVLYGPQGPTTQTNAPPFIELQVDWVVRLLRRMSQDHLHSIEPSKESCVFWKDLVTEAFESTLFRDSTAWWTGANVPHKRVEPLVYLGGIQPWRRLCERSLRDWTDFIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9U2</accession>
    <name>A0AAD8X9U2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_77125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359844.1">
        <property type="nucleotide sequence ID" value="XM_060515362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9U2"/>
    <dbReference type="GeneID" id="85399260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="16561" checksum="1C3AEEDD07271C7A" modified="2024-05-29" version="1">MRPLSRLHVSCTPLEGRRGASLPRVWPYIKGQQARPASNQPQSATDQHTTASKDNADPSTQTSVAGHDRQGATSPSSEKNKRKDGDHRSSHPKRSRARQQPQASGASHAEDSDFQRDPAHKAGRLWTPEEGASTPRRIDGGRSKEKDGDAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAD3</accession>
    <name>A0AAD8XAD3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_562284</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360007.1">
        <property type="nucleotide sequence ID" value="XM_060503575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAD3"/>
    <dbReference type="GeneID" id="85387474"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="129"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1714545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="40835" checksum="AF558C1D9F8D9FC6" modified="2024-05-29" version="1" fragment="single">IDVAWLRDRCGCPHCVSPSSGNKSFSTAEIPSGIAFESAKEMPDGSHEIRWTNDIPRAADVGHVSVFPATGPQSLAGLLIERPVLFFHHASVKKAERYMWKRETLLDKLERIDYKDYMEGGPAFRSTALSLAKIGLVFLTNVPQTEKAVAEIALKFGAVKETFYGHTWDVISKPDAENVAYTSSYLGLHSDMLYLESPPRIQLLHCLENSCSGGESIFSDALHAATWLERFHPESYDALTKYLVPYHYAKNGFFYRQARPVIADEHGRDREVWWSPPFQAPLPGTPDKSSSEAWQAWIKGARMFQETLEREDNMYQHRLQPGECVLFDNRRVLHGRRAFDTASGRRWLKGTYVADEDFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAN4</accession>
    <name>A0AAD8XAN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_638888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359321.1">
        <property type="nucleotide sequence ID" value="XM_060509389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAN4"/>
    <dbReference type="GeneID" id="85393288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="59" mass="6746" checksum="23FAFAB6C2B4FBCF" modified="2024-05-29" version="1">MEGTMPGALYCLLAFSTITPTRFLPHRPRYCRRKEQRGKGGTLNISSVKLITRKHRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAQ6</accession>
    <name>A0AAD8XAQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Brf1-like TBP-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_590115</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359396.1">
        <property type="nucleotide sequence ID" value="XM_060506305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAQ6"/>
    <dbReference type="GeneID" id="85390204"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="249"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="368"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="448"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="584"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="639"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="670"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="694"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="706"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="720"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1712278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="735" mass="82051" checksum="E776CC7CDE30F0A1" modified="2024-05-29" version="1">MSSFLTPTKKSQKPATKSKPFQPPNRIRAIREQAERQQASAAAAAAASAAAQAQQNRARPPTVAISNRPQCPNKACVKPNVVDGICQTCGRVADDSNIVAEVQFGETSSGAAMVQGSYIAADQAGVRSMGPAFRRVGGSDDREKTIREARALMQGYAQRLNLSDNTVNTAVQCFKLASQSGFTQGRKIITVAAVCLYAACRMERPCRVMLIDIGDIIQVNVFVLGRTFKALTKTLCLFPSGESPVFPEDIIYRFASKLEFKHMTNRVAEDAVRLVRRMKQDWIVMGRRPSGICGACLLMAARMHNFRRTVREVVYIVKVTNHTIQERLEEFNVTETSKMTVEDFLSQDFGSSSHDPPSFYRNTEAWQAQQEELGKKRKRTITDDGGNNRTTPAPSLPPPDLSAAPTIEYRRDKDGYIIPPLPSKIAVNEPALRDANSTQHLEGLAQEFGDAEKENEESSQTDTGSEKTRQSKPSLPINEEWEEDEAEMEDQISEIMNDPETYEHAKAFSNAEQRARIHSIWALQQQPDKAVSMAPEVGEDEFADDPEVANCMLTPDEIKIKELLWVNENKDWLRASQERLFRKKLEEKKPKKDRKRKKRPRIGEGQTTPASTPGEAAVNVMKERGFSKRINYEAIRQMFDVAGQGDPGSRPESEAASRPTSKAPSVVDDHYDEEEEEEIEPIDGNGGHEHQDDEYGGGDDYDDMGDESHMYDEDDHGMGEDDDDDDDFGLNDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAU2</accession>
    <name>A0AAD8XAU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_714361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000296">
        <property type="protein sequence ID" value="KAK1702944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357206.1">
        <property type="nucleotide sequence ID" value="XM_060511653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAU2"/>
    <dbReference type="GeneID" id="85395551"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF31">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1702944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="34498" checksum="D3F7ABE6EF11EED6" modified="2024-05-29" version="1">MTPTILIAGATGNTGRSVVETLSSFLSNSDGSPNIRILALTRSIDSSTAQHLASLPSVTMIEKNWVDINASWLREQNVIKAFIASHNSPSQFAEESTFHQAALKAGVQYVVRISTTGANVRPDFEAYYPRTHWAIETMLSSPEFKELKWTSLQPNIFFSAHLYSAVEFVKEYRQTKQQGILKLIADKDAPVGAIDPDDIGTFAAHLLWNQDPSRHNGAKYVLNGPTDVTGRDIVQWVEEAIGEPVDNVEFRDVSLVDAMVLATKESKNVISSIKAAPVTLWEGKCPASTTSKEVIEIAAPSRSIVDAWKALLSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCE9</accession>
    <name>A0AAD8XCE9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">18S rRNA factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_583792</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362152.1">
        <property type="nucleotide sequence ID" value="XM_060505697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCE9"/>
    <dbReference type="GeneID" id="85389596"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001147">
        <property type="entry name" value="Pre-rRNA-processing protein esf-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="116"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="267"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1721356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="335" mass="36981" checksum="BFC9A6466A63D0D5" modified="2024-05-29" version="1">MAPEKRNKFLDADESDDDLDQGYDSEAEELRKGGRSAKRRKVDSEDEDDFSGEEQNVTKGAEDAASDDEGVDEEEEDAGASTSTKKKSTKLDLPDVSKPLTKKNLVATEEAIKKSGVVYISRIPPFMKPQKLRSLLEPYGKINRIFLAPEDPTAHARRVKAGGNKKKSYTEGWVEFMRKKDAKAVCELLNARTIGGKKGSYYHDDIWTLKYLKGFKWRHLTEQITAENAERTSRMRAEISKASKENKEFVRNVERARVLDGIAATREKRGKAAASTTEGGASVDGGATAAPAAEAEKLDKRRTVFKQIPLADRKSEPGSAAKPAGDVARVLGKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDL3</accession>
    <name>A0AAD8XDL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_653182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363322.1">
        <property type="nucleotide sequence ID" value="XM_060510600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDL3"/>
    <dbReference type="GeneID" id="85394499"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039198">
        <property type="entry name" value="Srl3/Whi5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246:SF1">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="448"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="382"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="520"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="593" mass="63046" checksum="3F7F807828276D8F" modified="2024-05-29" version="1">MDSASIPPRLSHIQESDRQHFKMHSPATLQDTGLLPDKAARRALQPLTRPQAVAFPDALPIDKAASSLGDATANHHHNLNSHVHAPALAQGQQPQPSYQQPSQSFATSNHVPRIADHQPLKTTSIAASSVPSQVTPSTHQRPLPSSDSQTSSLSAEPANVFTPPASQGDMPGGSLNGHDSSQESQLLQLSHIAAAQDKLAEDNVMATARKRMADGALKENTSPVRMGHSRNTSTVSMASTTASSIGDWSSDLKTRLSYAMLKVNHGWQSHSIDEVESMASQAASPTSSHSTLHGRQELSASPRANMARYQPVSAATTASSGPSPATYESFWKEGQRSTHTSASPPAPVQNPNVPTLAPPAPIQPSRPMGGHNPRRNSNPRYTPTLLSHSHSASPHTPSQPNNNATPNQRLGRTPLIDPILFSPHQNVREQDAIESLLFMSSPGNSANMKHNYSSSAASNLPGRHALPSSQPRKSLPSQRPLPQKRVGFEKSPGGMTAVSDMDIDMDSPQSRGPMRRRINGSASFSGGTIGSTLRPQLSLPAALGSTSRPRPRLADADIERMIDQAAQAGDSSDDDDGEIQIPGRSRPEGAVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDP8</accession>
    <name>A0AAD8XDP8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364014.1">
        <property type="nucleotide sequence ID" value="XM_060510545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDP8"/>
    <dbReference type="GeneID" id="85394444"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="104" mass="11497" checksum="C05A24B20556EF17" modified="2024-05-29" version="1">MSIKHEMRVDSQMQTSSNTGTTYSCRQLANVPMSRGWARELDPSSFPPNKQSGFQAPQEDADALHSYLLRRLAYSSVSEHSNIQSTLVHPSASLCKAGTCIPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE30</accession>
    <name>A0AAD8XE30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_409305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362981.1">
        <property type="nucleotide sequence ID" value="XM_060502899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE30"/>
    <dbReference type="GeneID" id="85386798"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18834" checksum="6272C104EEEB7159" modified="2024-05-29" version="1">MGHDTTSTVYAGELQGIVLALEMAQADKQNGNHRSKVFIHNHRPFKVSRILLLAQPRHSGGDRSHLNYASRYDRPDWLDFPFDESSHRMTSRRGKRRCGINSQIPVRSLRDPYFHRRHVPVCLGRTDQLCRCNMIVAYTSMSCFSVGSERLCLTAPIEHQYRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE35</accession>
    <name>A0AAD8XE35_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_753950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362996.1">
        <property type="nucleotide sequence ID" value="XM_060514418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE35"/>
    <dbReference type="GeneID" id="85398316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="18"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="332" mass="35717" checksum="16711EDFF035FC30" modified="2024-05-29" version="1">MASSLPQTMNGIQIPRTGGTEVLTHHTDLPLPALAENQVLVRNEYAGINYIDTYFRTGLYKAPLPITPGREGAGTVVKTHPSVANQFKEGDRVVYMGPFGSYSGYSAVNAAQLLHIPDALPTDKAAAALLQGLTAWTFIREAGEVKEGEWVLVHAAAGGVGLQLVQMLRAMGAKVIGTTSTDEKCALAKKNGAEFIVNSRSQDLVEEVKKITGGHGVDVIFDGVGKATFDSDIEMAARKGRLVVFGNASGAVPPFDILKLGPKNLKVMRPIVNGYTATREELEKYSTELFDMITSGKVEVAIHKAYPLKDVKQAHEDLESRNTTGKLILKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEE0</accession>
    <name>A0AAD8XEE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_743911</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360595.1">
        <property type="nucleotide sequence ID" value="XM_060513145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEE0"/>
    <dbReference type="GeneID" id="85397043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="44"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="526" mass="57745" checksum="CAB59605E1B00BF1" modified="2024-05-29" version="1">MSQNAAAPTESAGGIPVTVDAAIANKRGALAWFSNAGIVKLNCVIALSLVSSYATGYDGSMMNGLQSLDTWQESFNNPGAQELGLLNAIQNVGQLLALPFCAWFCDRFGRKPALLVSASILLIGVALQGAAQNVAMFIVARGVLGFGLALNITAAPLMIMELAYPSQRAPLVSIYNSLWGLGALSAAWITFGTFRIGNTWAWRIPSILQGLSSIVQLGLCFFIEESPRWDAEAEKLLVKYHANGDASDLIVPLEMEEIRTALRLEAEASRTTSYMAFFQTPGNRRRFFIILAVGFFSQWSGNGLISYYLTLILNSIGYTSQDAQTLINALITLWGLFWGLLASVLVNRFRRRTMFLASTIGSLLCYVIWTALQATYEKQTDLTGAGSPGLAKGVLAMIFLYNVTFTVGWGALQVTYVVEILPFNLRAKGLVLYNLFVALALIFNQYANPVGVTNSKWKYYITYDVWLAFEAVVVYFLFVETGKMSLEETAVILDGNEDRLTEEVARKTEKLALETHAHVVEDNNHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF58</accession>
    <name>A0AAD8XF58_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_576173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365589.1">
        <property type="nucleotide sequence ID" value="XM_060504898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF58"/>
    <dbReference type="GeneID" id="85388797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF6">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="55"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="501" mass="55387" checksum="A1B070FB1ABD48C5" modified="2024-05-29" version="1">MDSTQNDKITQGADFKGADVDNVENNYTDPNAPRAMSPERRAAVEKSMKRKLDMRCSLFVLIYIMNYLDRNNIAAARLRGLQDDLQLDNNEYATCLSILYVGYILMQIPSNMVINKISRPSWYIAAAMLIWGMISTLSGVTTNFGGMVATRFCLGFIEAAFLPGALMILSKWYTRRELTTRNAILFCGNLISNAFSALIGAGVLSNMQGVLGHAAWRWLFWIEGAVTMGVAISAAFILPDLPTNSRGFTEEELYVAQLRMTEDVGEADADSDDMGPLDGLIMAVKDVKIYIMMLTFTAYVVGLSFNAFFPTLTQTLGFGYVPTLLMSSPPWAFSCLISLINAWHADRTQERFWHIVGPICVGLVGFVISMSTLNVAARYVALFLQASSYAGFIVFYSWISSSFPRPPAKRAVAIAMINAFSQLGNVAGSYVWNLKENGFRKSYGIVTAMFGITIVGCYIFKVILDKLNKELEQSEAADTANTSAEEAEASHRLGKGFRYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFI5</accession>
    <name>A0AAD8XFI5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase 2</fullName>
            <shortName evidence="6">MAP 2</shortName>
            <shortName evidence="6">MetAP 2</shortName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_631297</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361675.1">
        <property type="nucleotide sequence ID" value="XM_060508897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFI5"/>
    <dbReference type="GeneID" id="85392796"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF1">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="8">
        <location>
            <begin position="169"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="8">
        <location>
            <begin position="324"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="513" mass="55707" checksum="586ABC3C3E3528B8" modified="2024-05-29" version="1">MGSKTPEDQIPGGNGGPTSSGISSGGEPRGVHLTRDGDGSLGGGGDDDGDDDDEDEVVAGSRSLKNAAAADDDNDDDGPRKKKRKPRKKKKKKASAGATAMEQSDPPRVPLSDLFPSGSYPAGEAQAYTKARDAEKGAGLDMNTARTTAAELRYQSRPHLEDPSLLNDYRKAAEVHRQVRQWVQDTVKPGKQTLLEIATGIEDGVRSLLGNQGLVAGDALKAGMGFPTGLCLNHEVAHYTPNPGQKDVVLKYEDVMKVDFGVHVNGWIVDSAFTMSFDPAWDSLLAGVRDATESGIKVCLFLFTSFTVLFFGEDKNADSSMVQTAGIDVRICDVSAAIQETMESYEVEVGGKMYPVKPVRNICAHDIARYQIHAGKSIPFIKNNDQTKMEEGEIFAIETFGTTGRGKLYDDVGIYGYKLDYDAPAQVKLPFASANRLYKSIKEQFGSIVFCRRYLDRLGLDRYLAGLKSLESHGILDSYAPLADIKGSQSAQFEHTILLRENNKEIISRGSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK7</accession>
    <name>A0AAD8XFK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uracil-xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_619763</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365557.1">
        <property type="nucleotide sequence ID" value="XM_060508150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK7"/>
    <dbReference type="GeneID" id="85392049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="562"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="64038" checksum="6F26647A4674F132" modified="2024-05-29" version="1">MDEDQGPSQIVPGTAPKRTMGDRLRSTKNRFFTKEGLIGDYDYAFLFTPNLPFMRKSRKAAPFFGLNDRMPTLLALLLGFQHALAMLAGIITPPILLSGAAGANLTGEMQQYLVSTALIVSGLLSMIQITRFHILKTPYYIGTGLISVVGISFAIIPVAQGALSQMYANGFCPMDGEGNKLPCPDGYGAIIGSSALCALIEIAISFMPPKVMLRIFPPIVTGPTVMLIGIHLIETGFQNWMGGSGPCANPTSDFFARCPNISAPHALPWGSAEYLGLGFSVFVTIILCERFGAPIMKSTSVVIGLLVGCIIAAATGYFDRSGIDSAPAASFIWVHTFKLTLYGPLILPLLAVYIICATEAIGDITATCDVSRLEVEGRLFESRIQGGVLADGINGVLAALMTITPMTTFAQNNGVIALTRCANRSAGYCCCFFLIIMGIFAKFAASLVAIPSSVLGGMTSFLFTAVAVSGMAIITKGVPFNRRNRFILTAGLTLGYGATLVPTYFDNVFTYAGDNRGLRGFLDAIVLIMETGFAITAFVCMFLNFVLDEEIEDTEGHDVIPTTGIVTPKDVNGGESARGADSEDIQPVGHNTTGKRDEKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGK7</accession>
    <name>A0AAD8XGK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_653822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362650.1">
        <property type="nucleotide sequence ID" value="XM_060510656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGK7"/>
    <dbReference type="GeneID" id="85394555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="191" mass="21209" checksum="4D9195EFD672ED0A" modified="2024-05-29" version="1">MGMSLPGLQGTEISSLYEWHILNRGSHVRRVLEVIGGLGAAGPLLRFFGSASLISGDAALVDTSSAASRQNGYLLEVRNRHEARPEIEGNHFAKYNLRNIGPSFVKKAGKDSANAGETIGLLRLEGTYHLRKDCVQQRKRDGRKLTRVENIELGYRNSVTSLYKLSPVVYTSVGWTSDENTKERPHMEGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHA5</accession>
    <name>A0AAD8XHA5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Actin-like protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_223342</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367282.1">
        <property type="nucleotide sequence ID" value="XM_060501756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHA5"/>
    <dbReference type="GeneID" id="85385655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000029">
        <property type="entry name" value="Actin-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000006">
        <property type="entry name" value="Actin-related protein 3 (ARP3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="439" mass="47815" checksum="B1EDB81AD977C196" modified="2024-05-29" version="1">MANQTPAVVMDNGTGFSKLGFAGNDSPSFVFPTAIATKGAAGSAGGTGSGRPAVANKPSFLTGGAGSGGHLNSKRGTEDLDFFIGDEAIAASGGPGYGLHYPIRHGQIENWDHMERFWSNSIFKYLRVEPEDHFFLLTEPPLNPPENRENTAEIFFESFNCAGLYIAVQAVLALAASWTSSKVHDRSLTGTVIDSGDGVTHVIPVAEGYVIGSSIKSIPIAGRDLTYFVQSLLRDRGEPDSSLKTAQEIKEQHCYVCPDIVKEFSRYDRDPTRFIKHPVLHPGGRQVSVDVGYERFLAPEIFFNPEIYSSDFLTPLPTVVDNVIQASPIDVRRGLYKNIVLSGGSTLYKDFGRRLQRDIKQLVDARIRASEVRSGGAKSGGLEVQVITHKRQRHGPWFGGSLLGQTPEFRSYCHTKAEYEEYGPSIVRRFALLGGPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHH8</accession>
    <name>A0AAD8XHH8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIF35</name>
        <name evidence="9" type="ORF">BDZ83DRAFT_717757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHH8"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000328">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="213"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32042" checksum="D4A56ACCDA6540F7" modified="2024-05-29" version="1">MATPKTKHDWADDEDVEETSTELPAPQTISNKDGTKTIITFRYNDQGKKVKMTRRIRYTTHTEKVNPRVADRKTWSKFGLSAKDPAGPAPDTTSVGENIIFRPSTNWRKDEKEAGEDPGAQALKDKLKDKQVKCRICNGEHFTARCPYKDTMAPVGADGADVAAGLPDDPAPRLAAPEKGSYVPPALRAGATGGAGAGDRMGGSKYGERDDLATLRVTNVSEMAEEQELRDMFERFGRVTRVFLAKDRETGLAKGFAFISFADRGDAVKAAAKMDGFGFKHLILRVEFAKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHI5</accession>
    <name>A0AAD8XHI5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_750032</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367537.1">
        <property type="nucleotide sequence ID" value="XM_060513863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHI5"/>
    <dbReference type="GeneID" id="85397761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF11">
        <property type="entry name" value="GLYCOSYLHYDROLASE FAMILY 61-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042058759" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="12">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1727482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="24672" checksum="F022A0ADB267C243" modified="2024-05-29" version="1">MKFLTAAAVLSAAVSEVSGHYIFQQLSVGSTKYDVFQHIRKNTNYNSPVTDLASNDLRCNVGGASGAQTTVVNVKPGDAFTFTLDTAVYHQGPISLFLSKAPSHVQDYDGSGKWAKFKDFLPTFSNGQATWPMRQTYEYKIPTCLPNGEYLLRVHQLGIHNPYPAGIPQFYISCAQINVTGSTASASSFAPTLSIPGAFKDTDPGYTVNIYQPGFTSYVAPGGAEWTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJW8</accession>
    <name>A0AAD8XJW8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_611015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368110.1">
        <property type="nucleotide sequence ID" value="XM_060507633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJW8"/>
    <dbReference type="GeneID" id="85391532"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="33182" checksum="F8DB165743196AE2" modified="2024-05-29" version="1">MGLLNVSILTTPFFFYSASALHPLSEPRSPTNMTPLCGLAFASPFLPHTFLTLLHVSGIILFAQSWTLEPAAKPSFTDLSPDRRYTPDDSRRCACIQVVVASQGHPWSIFGLAGGASPRTRAEKVCCASEKGHHTINLVPVAAVPLHRLASLQGPCIASAQSLMNLRPLGGFGIRSAEAIFFSNNMEYGVRMVLLITLSLRDMVHVRIFSSVYAIRSPRLWRYTKEPLLRLCLNSRNESKAINPYPGAATSNRFVHRVPPLVSRPDYRLAFGDFWRSPLSHGCLQATGSGFSVLILTSLRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKF5</accession>
    <name>A0AAD8XKF5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_716737</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369055.1">
        <property type="nucleotide sequence ID" value="XM_060511875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKF5"/>
    <dbReference type="GeneID" id="85395773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1729000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="52895" checksum="39D0B74DD9E7EC5D" modified="2024-05-29" version="1">MASSSTSSPTLTRTETLSLGALSFAAVAVLLNAFQGEGEPLIASLALSVLAFALAYSMIRWLGPVFKQAGFKGRDLSKHHRPELPECMGAVCAAVYLLVVIVFIPFPFYKDIVAATSGGGNRDVVFQVEHVQQGRFLHRFPHSKLASYLSAIISLQTTALLGIGDDLFDIRWRHKWWIPGLASVPILVIYFVDFGVTSIVIPIPLQPYLGELFDLGVLYYIYMSCIAMFCPQSINMLAGINGIEVSQCIVVSLLLVLNDCLYLFTPYPHPATDSHLFSLYLLLPWLGVSFALVLHNWYPAKVFVGDTYCYFSGMVFATVGILGHFSKTLGLLLVPQLFNFLYSTPQIFGLIPCPRHRLPRFNARTGLLETSKTPWSPERQPRPLVAQGLHLLAKLRLLEVTVDEKGRFVETSNFTLLNLWLVWRGPLREDRLAWEVTFLQLFIGLFGLFVRHRLALLIFKEDNWGMTTKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL48</accession>
    <name>A0AAD8XL48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_606108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369354.1">
        <property type="nucleotide sequence ID" value="XM_060507357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL48"/>
    <dbReference type="GeneID" id="85391256"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="104" mass="11231" checksum="E5031FD20DC1C5B6" modified="2024-05-29" version="1">MRRRSSTQAASVSVSPTAIRRAASKTPDEITGLSSTAAVRSSIASRACDACRARRRKCHFDGSSPHAEGPSPTQCRDCCRLGIPCSFLVPTRPRGPKRRYEDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLD4</accession>
    <name>A0AAD8XLD4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_32532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369508.1">
        <property type="nucleotide sequence ID" value="XM_060502390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLD4"/>
    <dbReference type="GeneID" id="85386289"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041962912" evidence="1">
        <location>
            <begin position="28"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="78" mass="8736" checksum="8D79A000FBC98E6A" modified="2024-05-29" version="1">MMARNTFGFWFYCISAWHLLGLSCVMAGVEEAPWFFKPGQAQPIDLLDQPDAIPFWPGSIKVICETEAQGVRCDAKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMC7</accession>
    <name>A0AAD8XMC7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED19</name>
        <name evidence="11" type="ORF">BDZ83DRAFT_647550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMC7"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08633">
        <property type="entry name" value="Rox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="257"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="38516" checksum="AA6182F49E0AAF60" modified="2024-05-29" version="1">MSFHPRTPQSPSQFSPATSDLTSSMNSSAPSTATTLPTPAHSVNGSASQPSDMSQDIAMGDDSPHKRKRPLEDLGDRDQKKAHIEDSKTGIEALHLDVGEKYLLCQTPHHERLPRITEDLFEMFNLSGIAAEVAREKPNGEKNALRKTYKGQIKKLGILGRFDSVAQDWDAPREKDGESGDKKREVYHGFRELLEIPDAEYWGTRNDPITSGLSATVKSMLNRATTMAKGPLPVKDWDSSVLGDLTPGSMEALRQGLGGKVTAPGTPSATTPNPFARKQQQGPQGAVRPQRTTKKRGYGDNSFEGYGEGFPDDGYSTGDGDDRGGQKRRKKDNGNGQTFPNTMRPQGYGSSAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMI7</accession>
    <name>A0AAD8XMI7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-rhamnosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_689854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370124.1">
        <property type="nucleotide sequence ID" value="XM_060511295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMI7"/>
    <dbReference type="GeneID" id="85395194"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF5">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148368" evidence="1">
        <location>
            <begin position="24"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="256"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="3">
        <location>
            <begin position="582"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="663" mass="72139" checksum="AA9581C8C1CFDD24" modified="2024-05-29" version="1">MFISRPSIRALAATSLLASHCSAECWRNSTCDGPSSASFPGAWDKYNYAPTSRNIAPKYILSSLSGANISDFKAPVNLSSQIDGLVFDFGVEVGGIVTIDYKLSESPNATLGLAFTEAKDYIGRKSDNSNGGTGQDGALAYNITSSAAGTYVMPDSKLRGGFRYLTLFLTPADSSSTVSLEIRNISLEISFQPTWSDLRAYQGYFHSSDELLNKIWYSGAYTIQTNSVPGRTGRVSGTSGRTSWQNDAYIGPGETVLLDGAKRDRWVWIGDMGTAVPSAFVSTGDMESTKNALLAIYNYQSADGTLPKAGPPYLSSDTYHLWTLVGTYNYFLYTGDTDFMTSIWPKYLKAINLSRSKVTSKGIMNVTGAADWGRWTYSTERSSASMLLYRALRTGADIASWSPTLTNASSYQKEWTSAASKLQTSIMTEIWDDSKGAFKESPNNTSLYPQDANSMTVAFGVVSADSAEAQRVSDYLESNWTPIGPHCPELKNNVSPFISSIEIASHFRTGRPDRALQLIRDAWGWYLNNPNGTQSTVVEGYLIDGTWGYRGDRGYRNDPSYISHAHGWSSGPTSTMTEYLVGLRVIKPGGSEWQLKPVLSELLEAEAGFTTSLGKFSAKFTVGDDGTAVVEWDTPASTRGYLVLPGQKSVWVNGGKGNTTVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMK8</accession>
    <name>A0AAD8XMK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_567230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370238.1">
        <property type="nucleotide sequence ID" value="XM_060503936.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1351"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="942"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="965"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1441"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1463"/>
            <end position="1488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1536" mass="166140" checksum="54240552848C62DA" modified="2024-05-29" version="1">MPTHGRTRDPCQAQLHRPSRNIRHLRLHRLNYPRPHSAGPPGDSDSEPVSPVSDTHSISTTPRFHAKDTPGDDYSVGGDLQVPRPISKTQPSWDPFTGTPLVEEEGFEMGQSTDPSPPASHAGQGQAAALPPPPPPQATQAATAVRPRANTTDDPYDDWVVVSPQSPPSGQIHVVSPQSPPQAPRSFEPTESSREVDEDDHDATHGSSSTGLFIVQPTQQLQPVQQQPVQQQPIQQPQQQQQQTINHLPSQQTSPQRQSSFVGLPPIRRSSTFGINLTKRAKKRFPLDEDDENNFVSSPVNTTTDQYGNDGGSSSRFQQGESSWSAQSAQPMRVDTGPPRFRKDSNMSHNVLSATSTQAATLATESSGMTGQDLRIDDEKRPLGPGVAMKGAGRVPGPIDTRAAMQQNEGGTSGRPYGPGMPPHQGIMSPTFGGNPIHHLPPQGPWKLEESHLSEPLATSRNRQSGGSLSPHQQTSFGIDKETGVPSTAAQRPETQLPPRQKFSEVPPSSAQRYPGLFTPQAGYQNPSSPTGPRGSEDLGQHFYNRDSASLYRTQTGDSEVSGFDPSTDEDRGRRRSSGFFKEIGGRISRHTSRERPASKAESGAPSYMAGPDVRGDAVSEASVATGELQDRQRRRSSFFLNLRGSKPSDVGGPHGRDGIEGITPSPKASPNPGGPSQVQQPSLGGPAERKRSFFGPGADQSANLPMPNLSRSSTSTAGYEVASGAMGPPKKRFSGFTSKVFPRSSSQQDLQVPQKPSTSHSTATSTMFGRPPSTQGNQQRSTALEEVRVRPVSDLQSERREAPVAPGHEAHDEHVSRRKSSQILNMESHPSQSFDAPAPPSQREQPSPGRRHLTEQRQPSLSFLQAEEQLSRPEQPDDQTETHWVPPGFSAEPTPEPSIRHSYGRENSPGPQTPPLGQGQVANHQQALGVQKSGHTRRISEQSASLLSPSSNFRAQSPNGVAGQSDNSQRSSVSNSPKPSSAAQIPAPRAPLASESRAPPPDPRQPSPFSVRLNDHPSSQNLGLSSRCHIQARFKTCSRSRSCSSLTRARASKGCRQLFRYHREVIYHSKDLITYVPFEPVMTRAIPNGPEPSGSVRSNPQPYVEPQYDQVPIPQGYAAVHGEGGVAPSPYALSRTSPPVQYPAYHSPQVPQWGQPPVAQRHPSEMSMYSHPSPPIQQGQQLLHSHPHGGAWPEGDRRVSMASHQSNISHVSHSTQAAQVGPQGDVPIPNQQHQPQQDTRGIRLVNQNDSRIAGPDSQFGQQTMPPTQQPQQQRYSLVDAPVPVAASPQIQQSNSREPQGKQQTKSAEVQTYVSNTVRNAHDKPSSPRPQEHAQQTQGLAIDAGSMMVNNSRSVSDDKQGPAENIVSSEPTAPAPAPTAPRLSVNVQQANQEPKDNNDLYESTPRLPSNPSQPPAAQPIVAANTGHSMVSDSSADEAPRNASHANGSAGTAATTTLARGKSTRAELEDTEDERQRTMRREAQEEKILVDPYEELSSGGVKYRKEEEPADVPQMSATSYPGQEWNPYGAGGFEEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN75</accession>
    <name>A0AAD8XN75_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Origin recognition complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_566557</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370620.1">
        <property type="nucleotide sequence ID" value="XM_060503860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN75"/>
    <dbReference type="GeneID" id="85387759"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008721">
        <property type="entry name" value="ORC6_cyclin_first"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05460">
        <property type="entry name" value="ORC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC6 first cyclin-like" evidence="7">
        <location>
            <begin position="10"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="42932" checksum="ADEC9504CE35DC1F" modified="2024-05-29" version="1">MNRSIEQTLLSLMPTHGSALPPSLVELAGSLLAQSRHRASTLKADEEIGRLYACAHIACDRLKITLDLPPIEPRPPIPPRIYKRLYSHLDNILPNTALNRTPGKNGTPRNRQRHGVDSPVRTPHRPTPTKDRSLSQFRTGGNPAANGSVPNTPTKSTGKVAYPSDKSGLHFWIQPTIRLMCRETNQKHLAPTMLAGMEYVVVPGGLRTRDAWVRENLAALCGAVYFFVVQQVRKLATGEDVDRENYVPARKQVLELLAKAREEVDKRGLDEDEAWEGWAPVKSKEFDAAVKEVSERGWLDADWYRSLGDVIEAGHVIADSHGRGGENAGAYKAPVRGADTMFLERYDFLSEKKRRDYRIWKESILRRIDLMEKEDGDAMEVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XND4</accession>
    <name>A0AAD8XND4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_374044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370589.1">
        <property type="nucleotide sequence ID" value="XM_060502664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XND4"/>
    <dbReference type="GeneID" id="85386563"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="311" mass="35676" checksum="05BB8B73D467371B" modified="2024-05-29" version="1">MSTANKKEARVTFQTTKGHRHQSSDSSISVISSSPSAQDYFDLELKYNKLLDDMSRLKSETKARYAALENNIEVLKIDKKAWEREKDNLRTENQVLREDLRKAQRHSPSRESTKMSGALPSQPPSPREHKEREHREPREYKEPREHKEPKESKALRRSDSKHRTRGESKVRKPTEDKELAKRCQEDKVRLGRRFEHKDDKSTSSGSSRGSKQGSYIEPMGPSAPRPASIVEPTRPRTKRSESTSYAIRPTVLTTTTVTDSPYDQHTPGYPDHESPFSYEGSAYGHGHSPYVEDGSYYAHPLPETTRGRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNE3</accession>
    <name>A0AAD8XNE3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_601352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370552.1">
        <property type="nucleotide sequence ID" value="XM_060507093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNE3"/>
    <dbReference type="GeneID" id="85390992"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042103183" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7828" checksum="4F015C09B5F85975" modified="2024-05-29" version="1">MGRHLLVILLPSFAGTAVGRVTAQTNTRTRVLYTLSSGYHQPGRIAFRVRVRLLPRHEKRRLAGGVLECC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNR3</accession>
    <name>A0AAD8XNR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370741.1">
        <property type="nucleotide sequence ID" value="XM_060513361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNR3"/>
    <dbReference type="GeneID" id="85397259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037830">
        <property type="entry name" value="ZZZ3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705">
        <property type="entry name" value="ZINC FINGER, ZZ DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705:SF0">
        <property type="entry name" value="ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="30281" checksum="F649D9864D989300" modified="2024-05-29" version="1">MPGLTIQTDAISPRTSNAPAPAPSTSAAAAPTAATISSAGGTNPPHAQQTPPRSSRSSSPARPPISPITPTLPPARLPDPPAPFAADRPVLTHSSQLSAASAIPPPRPEPVDFDSNPDVLALKSAISILQMQSKKATADIQGLNAAKNAAVENPSAFLADLGAGKVHTQGDKLFAESDSDSDDETEGRADGSTAQGKAKEPQQPWESLPKPQNVVRCPPINWSQYAVVGESLDKIHADQLARPSQGAPATLGPSGTYEFKGEPGGNQRPFIGVAAPYTPGKDRIEKKAKGSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPG3</accession>
    <name>A0AAD8XPG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_294625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371083.1">
        <property type="nucleotide sequence ID" value="XM_060502208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPG3"/>
    <dbReference type="GeneID" id="85386107"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="21368" checksum="A85D04129999847E" modified="2024-05-29" version="1">MFPQSVALSSASRWSEREEASGRSGDVDSYGAPCVHKCLTTPLSSSFSSNKPYGVRIQRAVPVRLLRLALSCVPLYPCGNANLNSTSITSPHIAFPYLALAGSGPFYSASASAPRNLLLPPSTSPKLQAPSLTLTLPVSLIRGCVGKRLDRRHSPLFFVSSSALTIGSGWGAESRYSQPATRALEGWYGQAKLTVAVRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPQ8</accession>
    <name>A0AAD8XPQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371227.1">
        <property type="nucleotide sequence ID" value="XM_060513295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPQ8"/>
    <dbReference type="GeneID" id="85397193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="40375" checksum="FCC8BDBC507E1029" modified="2024-05-29" version="1">MAMISQDFGNTASGASVSQRSRTQRVVIHILHQALRLVRSRVGSKEAAYPLLLALFLSLSPRAAHEATRLRLKAAIDGFGHGQGLGKAPTTGNDGSQLLDTTVDITCSIAHCCGRATGQPSNSYFAKVCELIDTIQTPRFARLRGNGAFVLAQKTDDLRDLVFAETLKKDLAERDGMVVAKGNFTGFRWEEGISEWIAVSPLARRQGDFSRETLPRRRSGRHNSGKDDVRVLADRSEPDPTTEGADKTGPLVTASPGLTGQSIGDQVGRRLAGKRKSPDTQNEDHGSRKRNSGAGIAGMDGVDGVDELGMGLENWPRVLGKSRLGSHVAGARRRDGCRRVIRSSETWSRKVLADLGEQAILIDCGLNDEDELGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ52</accession>
    <name>A0AAD8XQ52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_167690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371700.1">
        <property type="nucleotide sequence ID" value="XM_060501433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ52"/>
    <dbReference type="GeneID" id="85385332"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="167" mass="18745" checksum="25832453E10106C0" modified="2024-05-29" version="1">MPVWVLLMTISLSNLKSPFGLRGLPHLAASAVRHSSTRQTMKACKGVTGKRRFWPQRAIMVARSLACTLDSRRLGRMDSGPGRWSCLPVSTRYEVRIASFRWVSDTDRSVDTLDSSELSVVGPQKTYDRAQMVPVPGDSRILTRYLFRRNVVGECVCLMLVHCQSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQL5</accession>
    <name>A0AAD8XQL5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_167639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371698.1">
        <property type="nucleotide sequence ID" value="XM_060501432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQL5"/>
    <dbReference type="GeneID" id="85385331"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042220745" evidence="2">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="238" mass="21273" checksum="E4A34A88710F66E4" modified="2024-05-29" version="1">MRYTTITLLVIGLLTGNALTAPAPQFGGGGGGFGGGRGGGGGGGGRGAVGGAGGGGGGRGGFGGGGAGAGAGAGAGAAGAGGAGGAGRGGGGGGGGGNRGQNAGQNGGGNNAGNNNANAGNANAGQNNNNNNQDDAAADDAAADANNGNANNNNQNNGNNNNNNNNQDNANDNANADDNANADDNADQAADADAAADFVGLACTDGTGAGACLADGQCDVNGDVKVVAGQCGQAAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D145</accession>
    <name>A0AAD9D145_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tricarboxylate carrier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_567873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369785.1">
        <property type="nucleotide sequence ID" value="XM_060504000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D145"/>
    <dbReference type="GeneID" id="85387899"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="347" mass="37107" checksum="59ADE340C5752838" modified="2024-05-29" version="1">MSASLPGSRELPASQYDLSTYMGRVRHNLGLTDPSTLLVGSTGLEQAKSLLTDYKQGKIPTMTPELWQAKKVVDSTLHPDTAEPVFLPFRMSAFVLTNLVVTAGMLQPGLGTAGTIAWQVVNQSLNVAINSANANKSSPLSWRKLGESYAMAVSVSCGVAVGLNKLVPRLKNLTPATRTTLTRLVPFAAVASAGFLNVLLMRGEEMRKGIDVFPVVAEKTQAAETKEQQAVEGAAASSQQPQSLGRSKKAAQIAVGETACSRVFNSTPIMVIPPLVLVRLQAQQWLKQRPRLTVPVNLGLILVTSYAVLPLALAVFPQRQSISADKLEPEFHGRGGEGGLVVFNRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1A6</accession>
    <name>A0AAD9D1A6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_603712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369890.1">
        <property type="nucleotide sequence ID" value="XM_060507237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1A6"/>
    <dbReference type="GeneID" id="85391136"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00976">
        <property type="entry name" value="CocE_NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF10">
        <property type="entry name" value="COCE_NOND FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="334"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="607" mass="67894" checksum="B4EF76B65ECC66A5" modified="2024-05-29" version="1">MSVKTPPIKDLLEVTEDQENGLTFMKNVSIPLKESPLPIRANVYLPLTSDKAARYPVLVTYGPYGKDIPYAKFYPKSFSEVAPDQRSKYSAWETPDPVFWTSQGYAIVRADERGLGQSPGLLDTMSRGTSECFFDVVEWAADQPWSNGKVGLLGISYYAGSQWRVAARRPKGLAAIIPWEGMSDYYRDRCRHGGIHSNKFIGFWWNRQVLVNQYGRKDRSKLDFPPDGPGARGQEDTIEGDLPEDVLVANRQDQTKDNEANRFRDDDYYSSKEYKLEDIEVPVLSVANWGGILLHLRGNVQGYLGAGSQLKYLRFITGRHDLPFYYPEEVELQKSFLDAFLKGEDRVGWSTPGKVPPVTLTLRKGNVGFNDAEKEKAYPKREETAWPIPRTEYTNFYLTPDLGLTTSGSGQDSKTVSYKALGSLENPQVVSFTSASFEQETEITGHVTAHLNVSVTPDNSGNETDIDLFVTLRHIDPSGQEVFYTGTAGDPVPLVKGWLRVSNRKVHDESPKHKSWLPHREYLSTDVLPVKAGEVYGVDVEVWPTNVVVDKGGKIVFEISSGDTQGSGIFQHCSEVDRPASKFAGLNNIHFGQGLENYVTLPVIPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1P0</accession>
    <name>A0AAD9D1P0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_603356</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370219.1">
        <property type="nucleotide sequence ID" value="XM_060507220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1P0"/>
    <dbReference type="GeneID" id="85391119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="109"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="381"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="61989" checksum="5D078C2E946B68F5" modified="2024-05-29" version="1">MASIPVTVSHQGTKYQVEIDTSSNGETFKYQLYSLTGVEPERQKILVKGKQVKDDDDMAKFGLKAGATLMMMGKPSGENADLARPKEAVKFVEDMTEAEAAQQEGATPAGLTNLGNTCYLNSTLQTLRSIPELQTALTTHKSGSGGAGSSFGLTSTDIATQLTDLYKNMSETQGAIPPLTFLSTLRMVYPQFAEKSKTGAGYAQQDAEEAWSQIISQLKQKLSESEGSSFIDRYMAGELQSTLEADEQAARDGGEEPVKSSESFLKLNCHIDASINHLRDGIMAALTEKLEKKSSVLDRDTTYTKKSQISRLPKYLTVHFVRFFWKREVQKKAKIMRKVTFPHELDVVEFCTDELKKALIPVRDKVREIRKDEEDIERARKRRKINPVDRGDVAGASGGPEGKTALEKANDKKAERAGKPVASTSDGDTGMTETFKTDAEVEAEKDAALTAAKKELYALVNQDLAKDEGANQSGIYELRGVVTHQGASADSGHYTAYVKKTAPVDPKTGKKGEEDGNWWWFNDDKVSEVTPDKIDALAGGGESHSALICLYRAIPLPTIDNEGKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1P9</accession>
    <name>A0AAD9D1P9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">RHD3/Sey1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEY1</name>
        <name evidence="12" type="ORF">BDZ83DRAFT_747396</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1P9"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="756"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="780"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="11">
        <location>
            <begin position="47"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="663"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="818"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="831"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="847" mass="95002" checksum="C1528325ED8AE2FD" modified="2024-05-29" version="1">MNGHFAAVGEEPDAQNYEHGIQVIDDQKDFNSHVATYLQKVRVAEAGFNYHLISVFGSQSTGKSTLLNNLFGTDFSVMSETMRQQTTKGIWMSKNKKESGMAENIIVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNLWETQVGLYNGANMGLLKTVFEVNLQLFLKDKQSSLRSLLFFVIRDHLGTTPLANLRNTLVQDLTKIWSSISKPQGLENSRIEDYFDFAFAALPHKILQADKFTTEIQNLGRRFTAGHRTSGASTQEFDGGVFLPEYHRRIPADGFSLYAEGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVLIGFDTAVVPLEEKQTESARAGKPAVLADLGVTGRESREKCLKAFEIQASRYHKGVYSRKRQDLEAKIDGRLKTLYNAQLSAAHKTAIASFSEHVSGAVKAGQKSGAAYEFAEIVTEEKKKTLEFFKTEAESLAIPGVAWSNFKSQYVLFEKELDDVSGKLRKEEMRRLATRVERWVKSRLGDAIGLEFNKLGSGRAGSGAPESGEKPAEKDLWDRIWTVFVDIVKDAQGRFTDRAKSFEATQDEVEVGLWRLRRKSWVALREKIEEEVMEGNILLKLRENFEDKFRYDEAGVPRIWRPTDDIEGIYTKARESTLTLIPLLSKFKLSESYGPPELPAWIGNQPRGVEPSDEEDLTPIGGVDEEDGKSLEEEMTVLSESKRQDLVIRFKKTADGVYVEAKRSAIGGVAQVPLYFYALLVALGWNEIVAVLRNPFLFVFLIMLAGGTYVAYTLNMLGPMYQMANAAANQGVEIGKAKLREFIENSDTARQALAMPARDSDSISMDTLDSRGKKKSAEDDIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D334</accession>
    <name>A0AAD9D334_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_726042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371136.1">
        <property type="nucleotide sequence ID" value="XM_060512750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D334"/>
    <dbReference type="GeneID" id="85396648"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="16879" checksum="AFA090C3A6F14440" modified="2024-05-29" version="1">MVRRALVLVSGKKGGGGAQVVTMGLGWKYGGGLRSPCIGTCVSAFPLMRRQRETLGRFSAWYWIASNCPWLRDPRKEAQEPMHGSPASFDFGLGRGREQPDDDMLCSTWGPRLRYPYQPVCSCPSRPVHHRHSMDIGLPRSGMSILSGVWTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7Y3</accession>
    <name>A0AAD8U7Y3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_110348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359112.1">
        <property type="nucleotide sequence ID" value="XM_060501085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7Y3"/>
    <dbReference type="GeneID" id="85384984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="559"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1711559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="760" mass="85097" checksum="92ED74A1EA729175" modified="2024-05-29" version="1">MSDEQSFTVEIPIRPREPRHRDSTFASHAKIEEVVHSPPFEHHFRLSQPVHHQPKCPEGLKIISGVYGKTFRDRSPTSSTMSSTHVPDSATTCSMPMSPTSSTFTRATTPDIDGPERLPTPFLASRSGTSGHRYRESCDSGSTFVDSIIGERFPAYPESIGAGHKEDPLPRMDIIEPDEDEQTDLPHTAGTPRPPSPDETPESPREERVPPRPLNERMSFDSGSDRLSRAWEPITPTPIDFSNEEADAVLDYVLQVTYGVELEEVTMPPAFLRHFVFRFIQDIGRFAFNGFPAGTQLTHTQSTSSNGSLPLARRSGSGRGSQNGKRKKGDTSRADGDDDGDDLTDDDGDSSVPFKRARQTPREAEGDLRLSCPFRKRNPHRFNVREHHSCAMTYFPKFAELRQHIVKQHKRNDPSSFMCDRCNRDFPSKKDLRDHQRLPKEQMCDVSDHDPESGIDGPTMTKLLSRKRASGMSTEVQWKEIWNLLFPDDDDYRVQPFDFCPVIEHFELQNQFMNSLKDVEDSLRNKGMTPQALETIGNIYRNQFIQVIEQCIANAQNMPYSNRSNRKNEPSPSRLLAPRHLTRTVPRPDSGVDVDEGSEDSQSVAIFPGGGFDGQGMLAHSDSVRTVRRASSTPEEFRGSVPPRTLQPLIEQLPASDFGLGGSPPVQKQSPSQQQLSQQPPMFDQQAELMPMANGMTPEMAAQLWGYHDGTMVPASGPSPSNMSMYAPVIDANGQPQFLDWNSGLQDHNGMYDFSGYVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8C6</accession>
    <name>A0AAD8U8C6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reticulocyte-binding protein 2-like protein a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000322">
        <property type="protein sequence ID" value="KAK1702071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357091.1">
        <property type="nucleotide sequence ID" value="XM_060506823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8C6"/>
    <dbReference type="GeneID" id="85390722"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205:SF2">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11885">
        <property type="entry name" value="DUF3405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="782" mass="89827" checksum="26ED1FC47E33EF42" modified="2024-05-29" version="1">MAKQTFPRGFVAPRVRPRTLLFLAFAGIVIHFCFKLRNESSVQLVSWHDVTHEPSPEGLVDQPPVSSIEQPMPPIDLSKNKDEELQQEKAEASKQEAESLKQEAEALQQEAEALKKEEEALKKEEEALKHEAEAVKQTEKKQKQEEEVRKHQEEEHEQKLRDQFAREYEAAKKLPGSGAIYGNTLNSLIDTDNRTDIHAARLRESSEEEKPYSNHRPVHFNPYPHYNGENWKKEEHRPYVPCVGATGELVEDLLVFKGRPAKFPKPSFGSFDIFNMDGNLCYERESRLGPYGHTLQIKANSLPVDWDSVDWGSLQDNCAKRNAARFGTGKLNAYVDTVYGNSGTAQRREARADGEEVSNKLSTISIGTESRTAVLLRTFTGKRYTENDKQAIRSLISELSLRSGGEYQVFLLLHVHDRSVNLKGDKTAYQHVLDEHVPREFHGITKLWNDQVVWDIYTALTEDDEKSVHHAQWLSVQKFSMDHPEFDYIWNWEMDVRVVGHNYDFLESLRGFAKKQPRRGLWERNERYYIPDHHGTWTEFRDYVEKQTAGTQVWGPPSVPFINPVGPKPPTGDPRDDQYDWGVNEEADLITLGPIFNPVNSSWIFADHIWGYKDQQHPATSLPRRCTIVTQSRISKRLLDIMHVENLRGNHIASEMTPQTVALLHGLKAVFAPHPTWFDRPWSGKFLDHWFNPGPKGESGGRGSAMGYGRERRYQGITWYYRAEPPSRLYNNWMGYIDTDVGGRDWEITNGRPCLPPMILHPIKDVNPTSPGFATKFELFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Y3</accession>
    <name>A0AAD8U8Y3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_589427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359697.1">
        <property type="nucleotide sequence ID" value="XM_060506231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Y3"/>
    <dbReference type="GeneID" id="85390130"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF234">
        <property type="entry name" value="MFS-TYPE TRANSPORTER DBAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="258"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1713371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="450" mass="47478" checksum="69D3D5899C3CE443" modified="2024-05-29" version="1">MTEKSGSVPDLRSTTPSETTLTPAAPADPEPQATPAAGAEPLTTSTPGPVPDGGLEAWIQVLGSWVILADTWGLVNTFGVYQTYYERTLPGVTPSAISWIGSLQGALLMMVGPISGPLYDAGYFRELLWAGITLIILGMFMTSLCTTYWQVLLAQGVCVGLGCGLVFLPSTAILSQYFHRRRALVIGLAATGSPIAGMCFPILFGHLEPRIGFGWATRIMAFILLGLSVIPAVSMHTRLPPSGHKRSLVDRTALRDPAFMLVMAGSFVGFLAMYVPYFYIQLFAVSHDIGPANFSSYFVTLLSAGSIPGRVIPNYLADKVGALYMQISVAAGSAVLMFAWLGIRNMAGLVVFAILYGLFSGGMVSISPTVIVSLSPDLGRVGTRMGMINFVAGIAILIGTPIAGAILGDYSGVAWQSMIGYGAAALTIGSMVLTAAKIFQLKGEGRDVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U998</accession>
    <name>A0AAD8U998_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amine oxidase</fullName>
            <ecNumber evidence="6">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_713656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2</text>
            <dbReference type="Rhea" id="RHEA:26414"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:58855"/>
            <dbReference type="ChEBI" id="CHEBI:65296"/>
            <dbReference type="EC" id="1.4.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000243">
        <property type="protein sequence ID" value="KAK1705331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357599.1">
        <property type="nucleotide sequence ID" value="XM_060511640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U998"/>
    <dbReference type="GeneID" id="85395538"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097621">
        <property type="term" value="F:monoamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050703">
        <property type="entry name" value="Flavin_MAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43563:SF14">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="7">
        <location>
            <begin position="154"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="174"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="66021" checksum="2475EF5DBA8BB3AF" modified="2024-05-29" version="1">MTKLIETVDLSNTSTAYYAPATITRADCLVHVSGLPGNTKDGQVPLDYDSQIHLALLNLRKVIIAAGSTVSNIASLTLYIVDYDASKRQHARHVQRFLGAHRPAMTLVPVQKLAVPGWLIEINAVVARPDVPSVPRSLPPVQEGVDVVIIGAGLAGLSAAHEARRAGLSCVVLEARDRVGGKTWSQPMEVGKDNGVFDLGAAWINDTNQSRMYELAKRYGAELIEQNTNGNCVLQDFDGKCSPFPYGELPKLSEPTRDHLAQIRDMAEADCQALDVFRPRDTSLDSLTFEAYLKSRGADSVALATATVWTRAMLGQEPKDISALYFLNYCKSGGGLLQMRSDRKDGGQYLRVRQGTQLFSKGLSSSLPEGVIRLSSPVQAVVQNENRSVKVEAGGKVYSAQKVITTVPGPVLKTISFQPTLPHTKLAWIESQTYGYYTKAMMEFSTPFWVEKGYCGLAQSFVGPASVIRDTSSPADKKFVLTCFMAGEPGKAWAATTTAERESSLLEQLSQLYGVENIRQLFKQMVFYEWVNDEFSGWGCPCTSLTPGVLDTLGGDGLREPYRDIHFAGTETAGEWKGYMEGAVRSGERAAAEVVKSLQGGLVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9A1</accession>
    <name>A0AAD8U9A1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_758839</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000274">
        <property type="protein sequence ID" value="KAK1703787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357352.1">
        <property type="nucleotide sequence ID" value="XM_060515098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9A1"/>
    <dbReference type="GeneID" id="85398996"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015233">
        <property type="term" value="F:pantothenate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098717">
        <property type="term" value="P:pantothenate import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF4">
        <property type="entry name" value="PANTOTHENATE TRANSPORTER FEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1703787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="484" mass="54320" checksum="C0BBC23B230714AE" modified="2024-05-29" version="1">MPGAISGEAAPLLPGSTISHRKREQPVSEMVSKIKEALWGPPSVERSLLIKLDFTVLIYFSVVWFLFGVNRASYNTAYISGMKEDLNFQGKDFNYMHTIYLVTYAVFQIPSTSLLTIVKPRYVFVAANTVWSVLTLVTFRATHVYQVFVLNGFEGAFSAIAYVGAHFIYGSWYKQSELATRAAVFCAFGNLGNMAGGWIQAGLLASLSNGPIEPWRLIFIVVSCITIPFAVFGWFAIPDLPEHRAARFLTPEERDLAVTRLGRTQTKAWDRSVFQRVLLSWQFWLLPTVFMLYSLSVQAIGNNVIPLWMASRGYSVIQQNNYPTATYATGIVATFVYCAVSDKLRSRWQASLCIGFTFIVSSAILISDPPDAGYFFAFYLMGTTYAPQALWYSWMADLTAHDLQLRAITTGFMNSFDFAFVTWWPLIFYPVTDAPNYRKGYIASLVTGALTVPVILLIAYLERRGRKLGKVGSAHDEHVESPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9V8</accession>
    <name>A0AAD8U9V8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_744213</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360192.1">
        <property type="nucleotide sequence ID" value="XM_060513154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9V8"/>
    <dbReference type="GeneID" id="85397052"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF4">
        <property type="entry name" value="SYMPORT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="122"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="650"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1715049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="676" mass="74628" checksum="84BB190E4A18E21F" modified="2024-05-29" version="1">MSDIDTLGQAESHSGHDVVSKQQARHRHINDRAVIENPLSHYTDEQLEADVTSFAERYLNVDKGALIRAARVAKDIKLYDEVARNPSDAAGKELPVQLTTEEKRALVRERDVPFSEKGMWTIIITVSLAAFLQGHVQASFNGSSLYDTEFGLNTTAKKDDNSATGSHAELGIDDWKLGAANASPFLFAAVLGCPLALPVNHYLGRKGGMVVAAFLILVSSIASAFATNWVHLFGIRLVNGIGMGLKAVSTPILASETAVGFWRGTSILAWQLWVAAGLMVGFAFNLVFDTASNKRLTFQLMVGAPMVPALALLVLVICFCEESPRYLMRVSSPRYDPQRAYEILKKLRNTELQALRDIYLVHKSIEQEEVPGANLKYIPGFVSTVVGFLRQWRQLFLERRLRNALISSSTVALAQQLCGINVLAFYSGTLFSRAGAEKRDAMFFSLGYGAVNFIFGLPAIRTIDTLGRRKWLILTLPVMALFMLLAGVSFNIHNLNAKVPVVALFILLFAAAYSPGLGPIPFTYASESFPLSHREAGAAVAIAVNLGFAGLLSVFFPRINSGLGDAGSLYLFAGLNVLALVMVFLLLEETKRRSLEDLDLVFAVSKRQFVKHQAVEYLPWLFRRYILRKHEYKPSLYIDLIWGSGGDEEERTRVRDAGRMDGRRDSSESDRDSAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA72</accession>
    <name>A0AAD8UA72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase/adducin N-terminal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000306">
        <property type="protein sequence ID" value="KAK1702567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357156.1">
        <property type="nucleotide sequence ID" value="XM_060515122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA72"/>
    <dbReference type="GeneID" id="85399020"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF25">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 14 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="240" mass="26241" checksum="AA0B51F3BD954A5F" modified="2024-05-29" version="1">MPSNVFARRGYSEGMAGHISLRDPEFPDRFWLNPLGVHFALRTPDDMALVNEKGEVIGGNTSRPVNAAGFLIHSAIHRARPDVVAACHCHSRFGKAWSAFGRPFEMLNGDTAMFYGDAQAVLTSYGGLVFEESLSDPVASALGLNGRGLIMQNHGLLTVGQSVDEAAYLFTLMERCCEIQLLVEAAAKDGLEKKCIDDATAKHTFETSSDSDSLYCEFQPEVQHEILLRGLKLGLGSYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAX5</accession>
    <name>A0AAD8UAX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_638791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359353.1">
        <property type="nucleotide sequence ID" value="XM_060509381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAX5"/>
    <dbReference type="GeneID" id="85393280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="455" mass="51278" checksum="F212E38F8AA97FB5" modified="2024-05-29" version="1">MSARRPMQADAVLHWQRFPSMADPLSITTSVLALLTTAAQSVKLLVETVNRYKGRDRTLSRLQAELEAFLRILDALHKVVETESAMMVLLKDPILRCSQLCNDFEKAMRVFSGKSKVGFRDWAKMEFMRGDINDFLDALSGYKETISIGLGTITMQTSKASQKVLEEYNEMIMDTIYRLNVRLQRIDEKMDGLTTEVAGSVDASGMTTDLEDERVITERCLRICEDAQHYLETLASDGDLLKQQLPPTNSGNNQVRFEAQLMIRRTLDENRDNFSETIGRLHERLASLPRNGTSQDESEKSRLEEDLKASKKCLEVCKAASETVAQQRIYRVGELIADVESDQVVITTLADLFDVKKASSTNGSAQWIGSFTDETARQISTDRYRSRFGALSSTEMGTTTQVPRDSWTAKDHTARRTNTDRQPSAREATERRPIPNEVRRRASGADGKRPANDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAY4</accession>
    <name>A0AAD8UAY4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_638853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359368.1">
        <property type="nucleotide sequence ID" value="XM_060509386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAY4"/>
    <dbReference type="GeneID" id="85393285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="28191" checksum="F209993B25E12AE0" modified="2024-05-29" version="1">MGTGSSSSSPSGGWWDCFLFRLARAFRNRDKNDWQRVVAQKKVGRFGEFFRFDVEFDGSEPPLDSLSSFDDEEDDGCTFEGLPALRRLRLCARAELFVFELHASRPYLFSDGGYDCRGQICCRLRARSESLTALMRQLASGKAYFRVGGHKVACDFASYPAAFLDGHFRLDVKFRVASLQESLAICLWETADEGRDISGSPFTVQQLVRSQKLEQCFGTSDHRKKRRRDDDDDEDEGASRKQPRFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBA9</accession>
    <name>A0AAD8UBA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_591778</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358650.1">
        <property type="nucleotide sequence ID" value="XM_060506473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBA9"/>
    <dbReference type="GeneID" id="85390372"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1709739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="530" mass="59967" checksum="E01D177B06635E90" modified="2024-05-29" version="1">MEIFSLSVGFVGLLLISFAIERVLNKLKNGRRPPLPPGPKGLPIVGNVNDLPKAGELDYVHWLKHKELYGPISSITTMGQTVVILSDPQLAFDLLDKRSLKHSSRPSQTFIGEMVGLEHITGMAVYDERFRAQRKAMGRILGSRIAAAKYNQWQEAEVGHLLLHLLDDPQNFVEHIKREAGSLILKITYGYTAEQFKEDPFLDMITETMDNFSTGATPGAFIVDVFPFLRYLPSWVPGTGFKQLAKQWRAQMEETRDKPYAFVQHQIAQGKDNSSYLANLLDSSEQSPFDQHNNKYSALAVFGGGADTTVSTVASFFLAMMVYPDAQKKAQEEIDRVIGNGRLPTTKDRESLPYIEALVKEIMRWHPIGPMGLPHSSTEDDVFEGYFIPKGAMVLPNIWWFTHDPERYPDPMNFKPERFLQTDGHEPEADPHKFVFGFGRRICPGRILADNSIFLNIAQSLAVYDFTKPIVDGKVVEPVVNFTTGVISHPQPFEVCIKPRSAEHERLIRSIEEIYPWEESDSKILERMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBU1</accession>
    <name>A0AAD8UBU1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_124159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358905.1">
        <property type="nucleotide sequence ID" value="XM_060501170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBU1"/>
    <dbReference type="GeneID" id="85385069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="25512" checksum="9FA16B16BCAABEB8" modified="2024-05-29" version="1">MSLFAAVFRRSCFLVFDYRLSCWVLRCCWWCCCLVIGVGWISGVLFSNHKVIYKVQRMFSPGDYATKRREKGVPSRGKVIPLSQLRCAPMAAISMFVKETLGNEKKATFAGRLARCPEGGPGEQFFRQVGGFCSELRGACAANLASGRDLPTPLGIGIASESQCSKLNHQVEKNPDQQNARTLHAINDGVGLRLVGKTGGPASDLSEASKVEIDPDSDPESLGPRLHILFWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCE4</accession>
    <name>A0AAD8UCE4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_639359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000156">
        <property type="protein sequence ID" value="KAK1711636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359189.1">
        <property type="nucleotide sequence ID" value="XM_060509420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCE4"/>
    <dbReference type="GeneID" id="85393319"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="64813" checksum="BBBD2DD5E345616F" modified="2024-05-29" version="1">MALDQYTYVFAIGTFFAMLDAYNNGANDVANAWATSVSSRSITYRQAMIFGTIFEMLGAITVGARTADTIKNGIIPNSVFNGNPGVQMLAFTCALAAASSWVMWCTRHSAHVSSTYSLVSAVAGVGVAVAGADKVQWGWNGGKGLGAIFAGLGMAPAISGCFGAIIFSLIKFVVHVRKNPVPWAVWTSPFFFLIAGTICTLSIVYKGSPNLGLSKKPAWYIAAVTMGTGGGLCLLAALFFVPFVHAKVIKKDYTIKWYHFVYGPLLFKRPAPADAEKAKVPNYAVVQEDEHEQTLPSHESVKSSESGDEPLKETHEKETHVPQERSLAAAEIGQGPTYKQLQAEGEAKLHAKMMKKRGPLGWAMRTLRDNPMGAGQIYEFHNMKIALKRIPAMITVGALYGLHYDIHAAQTGVAGTPEGERMKRVYASAKKYPNEVEHTYSFVQIITACTASFAHGANDIGNSVGPWAVIYSAWSTGDAAAAKAPVPVWQLAVLSATISLGLITYGYNIMKVMGNKITYHSPSRGSSMEMGAAITVLVFSQYSLPVSTSMCITGATVGVGLCNGTLKAVNFQRVGLLVFSWIMTIPVAGTLGGVLMGLFLNAPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCF8</accession>
    <name>A0AAD8UCF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_592806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000199">
        <property type="protein sequence ID" value="KAK1708203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358235.1">
        <property type="nucleotide sequence ID" value="XM_060506567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCF8"/>
    <dbReference type="GeneID" id="85390466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF1">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE STHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="17"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1708203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="38369" checksum="5FF057C9495C5D66" modified="2024-05-29" version="1">MAKGTTITALVQSPNGGGPPLVSRDRPMPQIREPHDVIVKVSAVALNPTDYKMPDYHPVPNAIMGCDFMGTIVAAGPEVDSTCVGMRVCGPMHGSNPGNPDSGAFAEYLIQDRRLLVRVPDSWSDLEGAALGGVGWATVALAMEDSLLLTGTPSKPAPLRSDGTRVPVLVYGGATATGTMACQLLSSAGYDPIATCSPASSALVKKYGAASTTPYSSPTCGETIRDATKGSIRAAIDCITTPESVKCCFTALGRAGARYASLEHAPDEWRTRKAVKMDMPMTYVVMGREVKLDGVYHRDADQSKFDLGARWALEVQTLVDEGRLKCHPAREVPGGWQGVIHGLEMLKSGQVRGQKLVVKVGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCG1</accession>
    <name>A0AAD8UCG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_639993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358998.1">
        <property type="nucleotide sequence ID" value="XM_060509461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCG1"/>
    <dbReference type="GeneID" id="85393360"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="296" mass="33423" checksum="2501A12FDAFBB208" modified="2024-05-29" version="1">MTPLADGWLSPKLPWGSGYCKHHNSICLRATNINIVSSSEFFYVILNIISLAFGSTYAYDSTLAKFISYTSSILSWFFDVSQALTFLALFYLARAFTLLRVDETSKRFRIGKTFSLGAVILISVLSFTAMCLWMSTRDGYYSWSYDSSDYERVMTRRLVAQIFDLICGIFNLLCAIGAITYIALVRKNALKDPLHKASNLALAISIIWLIRAVWSLFAQLSSRYGYSYYNYDTYTWFNIVSLVVGILGSFAVFIMLYFLATQDKYGLNTRGELVQPAKLNDEEASGAHITTANSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCK9</accession>
    <name>A0AAD8UCK9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_118863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359073.1">
        <property type="nucleotide sequence ID" value="XM_060501139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCK9"/>
    <dbReference type="GeneID" id="85385038"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251059" evidence="1">
        <location>
            <begin position="20"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="11849" checksum="FCE5540DCB7D9E21" modified="2024-05-29" version="1">MHFASVAVNFLAFLAPAWAYEVATDKCCQSQLEACHKQGANACMWTNAAICVDNPKNRVPVDDTCLKACPDATVKNPNGFLYKFQKHGAPAGDCVCGNLNPNLSKYCYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEM2</accession>
    <name>A0AAD8UEM2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361577.1">
        <property type="nucleotide sequence ID" value="XM_060508920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEM2"/>
    <dbReference type="GeneID" id="85392819"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052988">
        <property type="entry name" value="Oryzine_lactonohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47064:SF2">
        <property type="entry name" value="SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="365" mass="39477" checksum="F90F0274B85A138F" modified="2024-05-29" version="1">MSLINVDLHALATGGAGYLASINAGATLPTPAISLLAYQPAFADVLGPNATARKIVEVDWQAFHEGGIYNKKDNSLYISSNYNPTDNINITVLNLNDFSIRSTQFDGLTEANGGSSYYPPGADQSATPPMQVWCDQGDLTRKSQLLAVDPNTNKSEPLIVGFNGRNFTSLNDVRQHPVTGDLWFTDPQYGFFQKFRPESVLPTHVYRFEPSTGTVQVVADGFQQPNGVEFSPDGKTLYVSDTGAITTAPNLSGPATIYAFDIIDNKKLANKRVFAYADNGFPDGVHADTDGNVWGGCGDGIHVWNPEGALLGKIHLGETSNNFAFAPGKVFVFSNQRLWVVENLKALGREVCKDFGADSDPRCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF54</accession>
    <name>A0AAD8UF54_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_756051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360584.1">
        <property type="nucleotide sequence ID" value="XM_060514695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF54"/>
    <dbReference type="GeneID" id="85398593"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF236">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="10"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="48326" checksum="076D85D234B59671" modified="2024-05-29" version="1">MERLSDTGISILVVGAGIAGLAFAIESHRQGHSVKVLEKRIDPGDYGEIFFIQSPGLHTPSKWPGFMERLNKSAISAEFQFFKFSGEKLFGTKLGNPHLPTISVSRREFYLLLLTYATELGIPIETGQEVEDFFENEELGGVVLTDGSKLTADIVVAADGVGSKSWGIVTGTKEKPISSGFAEFFKDKREWTSLHIGPGAHFFTGLSPTEFCWGLTHRDEDAAVEDWNRIADSTGAFKYVEGWTPIVHEVIKSTPNNQATDWKLRFRDPQPKWVSDGGRVVQCGDSAHSFLPSSGFGATTALEDAFSLAACLKMSGRESAAVATKVHNKLRFERTACVQKIGFKSREAFHHTNWDEAAKNPRSIAKFTGSWLLKHNPEQYAYDNYEACAAHLLHGSEFKNTNTVPGFPFKLWTVQELLNKSDKGESIDDDEGDWYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF62</accession>
    <name>A0AAD8UF62_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MGT family glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_635325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360396.1">
        <property type="nucleotide sequence ID" value="XM_060509163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF62"/>
    <dbReference type="GeneID" id="85393062"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000072">
        <property type="entry name" value="Glycosyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="3">
        <location>
            <begin position="307"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="47263" checksum="86AA3747DC76EFE9" modified="2024-05-29" version="1">MNTMHLSTPDETATATATTTKTRQPLKFLLHCFSATGHVLPMQAVARELVERGHEVVWTTIAPQEQRVLASGANFVAAEEVVKVDANLDGANPKDMAETAEVMFRGRVTAQVADIRRVLNTFKPDFVLNDALPQGVAALHELGEIPHYATLGVVPLYLPDIGPEPIEHAAQSALGLLISQPQLVLPTINPEREKLGLPALKVTDTYSYSPFLHIQASCPSLEFQEGSEPILPQAQYVGPLVTRLAGASIGVPTWWQDVLDAQSIIGITQGTFAMDPTSLIIPAIKALQGDKNHLLVVPSKLVDEIRDKVEIEDNVRIADWVPYDLLLPRCRLLVTNGGYGSVTQALSHGVPLVCAGTSEDKKDTAARVTWVGAGIDLKTDTPSVDQVRDAVHKVLNETSYKENATRIGEELNAQGGAKRACDLLEKAAIELAAPTGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC5</accession>
    <name>A0AAD8UFC5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_39630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360689.1">
        <property type="nucleotide sequence ID" value="XM_060502822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC5"/>
    <dbReference type="GeneID" id="85386721"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000142">
        <property type="entry name" value="Similar to FCP1-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="158"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="510"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="335"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="609"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="651"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="727"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1716759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="836" mass="92380" checksum="693E16A9855664AB" modified="2024-05-29" version="1">MGKLLSLGARLRYPITITKLLKRPGDAVQKQESVLEYSFKWMREVGDPIAGNTWQEEETTVVGWDSPAEGTLKEWRLKEGMTFTRDAPCMMVEEACSHEIQFQGLCAICGKDMTEVNWATAERDTQRATINMTHDQTGLMVSGDLAARAESDTQKRLLRQRKLSLVVDLDQTIIHACIEPTVGEWMEDPSNPNYNAVKDVKKFQLNDEGPRGMVTSGCWYYIKMRPGLAEFLEKVAELYELHVYTMGTRAYALNIAKIVDPQQKLFGNRVISRDENGSMISKSLQRLFPVNTNMVVIIDDRADVWPSNRPNLIKVVPYDFFKGIGDINSSFLPKRQDILPAPPEPEAKPTPVAATTAAQTSEASTADQPNGKVSAIDELVKMSSGDDKVLQEAQSGEQERLLEQQIKERPLLHMQEALDKEDEQNEKATQETENGAHIMTVQHRSQVLRDDDAELHYLQQHLAQLHHKFYTEYDEKRAAAPAQSAPRKKTGDDGIDLDAVPDVGEVLDTMKAATLEGTTIVLSGLVPLGVDVLQSEIGIQAMSFGAQISTRVSKQVTHLVISTSRPRTQKVRQAAKMPSIKIVSQNWLSDCLSQWQRVDEAPYLVEVHPADRRQPAMSESTDAETISDADGDDSRPHLTIIDETGEQRVLEEDDDASDEDEGDQDGDEENMMLEFEDGQVSPIDGLKSFDWEGVDDEMKEFLGSDDDSSDADTESRSGDTDAGEDLPSSQESSNAVTGGTKRKAMEDDTASDEGGSALSKKQRIAKSRGASKLSSVRTPNVEDNNESSSLPTPQVTGDEEDVALIPDNVAANGLDDFDEDDLEADLEAELAAAGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFM7</accession>
    <name>A0AAD8UFM7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5 12">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_586855</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5 12"/>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360839.1">
        <property type="nucleotide sequence ID" value="XM_060505985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFM7"/>
    <dbReference type="GeneID" id="85389884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046456">
        <property type="entry name" value="PMI_typeI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="16">
        <location>
            <begin position="7"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="17">
        <location>
            <begin position="169"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I C-terminal" evidence="15">
        <location>
            <begin position="359"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1717352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="454" mass="49562" checksum="D76A743E6018D090" modified="2024-05-29" version="1">MVLQVPLFKLQCGVNSYEWGKKGGDSAAARFAATTPAEGFSIESEKPYAELWMGTHPSNPSKDLQSGRTLLELVQDNQQLLSAPISSKYGSKLPFLFKVLSINKALSIQAHPNKKLAEQLHARDPKNYPDDNHKPEMAIAITPFEGLCGFRPLSEISHFLATVPPLKSLVVEDKADEFINTVKGEEESENPEIKDRNKKALQHAFAALLSATPEEIEKQTEKLVALAKSEGSNFAGGGVATTDGETLSELILRNHAEFGADIGLFVLFFLNYVKMEPGEAMFLVADDIHAYLSGDIIECMAASDNVVRAGFTPKFKDVPTLVDMLTYNYAPIDEQKMSPSEYPYATLNRAAYSSGSAVILYDPPIEEFSVVRSLLNGDGSKVTFEPIEGPSIVICTSGKGTISVGPTVQKISEGNVFFVGSTAELVLQSEGDDDDEFVTFKAFCEIEEKPEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGE0</accession>
    <name>A0AAD8UGE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-NAD kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_582633</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362683.1">
        <property type="nucleotide sequence ID" value="XM_060505569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGE0"/>
    <dbReference type="GeneID" id="85389468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000009">
        <property type="entry name" value="Poly(P)/ATP NAD kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF26">
        <property type="entry name" value="NADH KINASE POS5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="50490" checksum="A7653312A63FB606" modified="2024-05-29" version="1">MSRSGAFRLCARPGAAAQIRAFRPLNFSTTAPVRAAEIRDVSSLPPRVVPKYRDPPNSTSGLLSLHWPTPPRNILLMPKLRSPQVLRATIDFAKHLQSTYSGLNLIFEPRVAQMVHESFNFPIYTCDPSAFPDRIDMITTLGGDGTILRAASHFSMYQAVPPILAFNFGTIGFLAEWKFEEYKRAWREAYMSGSGVAADDLLTPHTRVASGEKEHDVKDGAQSGWHASPGKSMGQSRAAKILLRHRLRVGVYDNNGQNISSQLLPTTKSQAHLPAEHPEDTILSKRDIPQPIHALNELLIHRGPKPHLAHIDIYLNNRFLTEAVADGILLSTPTGSTAYSLSAGGSIIHPLVKSLLITPICPRSLSFRPLVLPLNTKVTLKVSSKNRDGELEVSIDGKRSAGAGIGTEIRVEGEMVGESSNGDWKGGVPCVICGPGKGDASDYDDDGWVGGLNGLLMFNYPIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGK7</accession>
    <name>A0AAD8UGK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_783077</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362803.1">
        <property type="nucleotide sequence ID" value="XM_060515578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGK7"/>
    <dbReference type="GeneID" id="85399476"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="488"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="589"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="873" mass="98566" checksum="F607690676F1607F" modified="2024-05-29" version="1">MRLKSHNSEGRPHTTYEKMQDKTANLDKEACEIQEFEFSPQATSSSSIPAKAPYPRHPSNQRRTNIMIDPFSVALAFAGMLVIFMALSYLGSLIYQLFRDNGLFDPKSIGCLTFVIFILASIHPLTGDRAHSVLFSVSAVVLEAVWGLKIAVIRLRDTLRRAFASRQPASNTDLQQVALRQLPEQTVEQPNPTPAQEDPDRCYRQREVCDNAEQRLTKTLRQSNSYASEVSELDAKVLELQHAINVQQSRAQQAENRVREANARLLAHETDGATIARLEAELEYQKAQAHDADVCREASNSQAKYLQKKIDTQKEKFQEYARRKEDQIGVLRTDIKALQRQKDSPPRVELLATGPQSEAVETAPETAQQYLEEQLAITQARLTVNQALATSATFERFISKTQMDDLKADSQNTEQNLLIIIVELRKELAKAQAQATTATQWQVTQQNIEASTSGDILALQTDLANIKAEAKATIESQGAQIQEAAGFKAEAERVVADLRSEAEQLRRENDNYKQKVEQMAALRPQIALLQQEAEQIRVERNALQQQVEQLMDQATQIAPLQQERDVATRKVQLVEQQAVELLQAKAVQVTKLEVDLRTVRKEKKKAEEEIKGYFQELEEEQERLRKSLESEKAAIKTMSDLKVANDDFCAETERLNVEVQRLLNENTNLTARMKKFANEELLKANMAKKNKTQELNNKDGILVFTKKTHEDELEKKEAELAEKNEKIAKLESQYSMSCAGRLTLRDKTKKGREDLTLLASRVRDLEGQIRNPKSGPRLTALQTGSVSTVLQQIEEGKHLLSLTSTPEKKPERAQSSSDAKPMRPMKPLPNRRRSEQLSKSEAGPSSAMEGMVTIKDTVYGYGYGDDYEILLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHF0</accession>
    <name>A0AAD8UHF0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_395369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363283.1">
        <property type="nucleotide sequence ID" value="XM_060502815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHF0"/>
    <dbReference type="GeneID" id="85386714"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="7970" checksum="0F03DE653A3BE5EB" modified="2024-05-29" version="1">MSVSMSQWHKDECTRDLQGSQPSHNGIDIDPCTPVGGSKRGSDAQSSAALDSISLPTAQLKASVSSPSQEPKRGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHR3</accession>
    <name>A0AAD8UHR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_731307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364216.1">
        <property type="nucleotide sequence ID" value="XM_060512867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHR3"/>
    <dbReference type="GeneID" id="85396765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041973335" evidence="2">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="173" mass="19938" checksum="FA09EF9735853D2B" modified="2024-05-29" version="1">MKLSTTLAILLAPLAVFAKPPKRTSARHVRIDRLPTCIQYCIGETQWRLKGAKLPNLAGEWCAKAAPPHTPDWISFGKALDECKKHQCDNSIQWIDLAVWHWDMCEFSDVREEGMNFFNGYRKAYWLPNDRQPIRPPHSRNWISDETFEAPDEWNENNGIGDDIVDDQPPLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIC9</accession>
    <name>A0AAD8UIC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_653135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363407.1">
        <property type="nucleotide sequence ID" value="XM_060510595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIC9"/>
    <dbReference type="GeneID" id="85394494"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="214" mass="23696" checksum="CBE6DB8149B8EAE0" modified="2024-05-29" version="1">MRLPEVSRLQMVSSFTHPRDPDLLTSSNSCLKVGIRKVPEVRGHSTTLTLSSNSLYDAHYHQRQMREEDTHLEPKQRGHMGIAFPRFDLLSCSVRHGSDADGVLATICRCNASLPPRPAHGTGDFGAPEPLSFGLAMIGQVGIPYDYSGVWTDDLCQSTDIPSFELDSALLSRPLQLETWFACLPRHSKASHTSAHVLFLSIRMLLRSPSCLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIR2</accession>
    <name>A0AAD8UIR2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_653925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362505.1">
        <property type="nucleotide sequence ID" value="XM_060510670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIR2"/>
    <dbReference type="GeneID" id="85394569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="170" mass="19848" checksum="C94A7F3323800452" modified="2024-05-29" version="1">MAEHATHEETHDSVPDGFFCTFCSSPYLEARNWRLCEQSHAEQRIQDLNGIYWVCSLQDRDNDSGLCNTSFEVTQRFEFAEHLIMMHGVGTSWNEVLSVQRENCFPIYADGFWCGYCQKALKYDDPQIQEGLALRGLDQPLRLDHIQQHIIDGIRPRSWRWPRQGVTEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIZ1</accession>
    <name>A0AAD8UIZ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_363886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364183.1">
        <property type="nucleotide sequence ID" value="XM_060502594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIZ1"/>
    <dbReference type="GeneID" id="85386493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="291" mass="31661" checksum="01416B1ACAE6BD52" modified="2024-05-29" version="1">MSFPAPTKTYRTQPYAAISPSRPELSSKGKSAFISGGGAGIGASIAKSLSKSGITSLGLLGRTIKSLEETKTAIEALNAETKVFLYTVDVTEAKATTDAVTSFASSVDGGKIDILVANAAYMSDLKTITDSDPEDWWRAFEISIRGNFNLLRAFQPVATPNAAVIHISTAAIHLPYMFGYSSYRASKSGATKMFEYFRDENPGFFVLQVHPGLIGGTVMSEKFAPSVEKFGLTYDDIALPGDFVVWAVSEEAKFLNGRFVHANWDVEELVMLKESLEKDQSRFTIGLQGWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL25</accession>
    <name>A0AAD8UL25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dihydroorotate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_753456</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363558.1">
        <property type="nucleotide sequence ID" value="XM_060514350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL25"/>
    <dbReference type="GeneID" id="85398248"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009220">
        <property type="term" value="P:pyrimidine ribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000242">
        <property type="entry name" value="Dihydroorotate reductase PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="8">
        <location>
            <begin position="129"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="8">
        <location>
            <begin position="448"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="53147" checksum="6577926397529D6B" modified="2024-05-29" version="1">MASICMRSCRVQSALRSTKNSTTLRPRLPGNIPRRHASTGTGSSTESQAGSGLKTGLYSIALAGSLYVSYLYVTDTRASIHALSPMLMRFAWSDAEDAHHAGTGMMKTLYDLGLHIRERDRTLAEHPALATEVYGMKLSNPIGISAGLDKHADIPDALFALGAGIVEVGGCTPRPQDGNPRPRVFRVPSLDGMINRYGLNSRGADSMAITLRERVRKFARKVGATEQEVLDGEAGVPAGSLLPGRLLAVQIAKNKETDQKDVNAVAQDYVYCVQRLARYADILVVNVSSPNTPGLRDLQATEPLTRLLSAVVQEARKVDRKVAPKVMVKVSPDEEEDAQIEGIVQAVCSSGVDGVIVGNTTNRRTGIVPQGVKLTVKEQKALQETGGYSGPAMYNRTLDLVGKYRKKLDAQTLQTGSAEEAAAIPDIDGSLSGKLHDLIEGKDTPRKVIFATGGITNGEQALKILNAGASVAMVYTGLTYGGPGTITKIKREIKDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULI6</accession>
    <name>A0AAD8ULI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_793724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363349.1">
        <property type="nucleotide sequence ID" value="XM_060515789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULI6"/>
    <dbReference type="GeneID" id="85399687"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="40223" checksum="14F3866738FAE236" modified="2024-05-29" version="1">MSSEGQDTNTAESESGPAGSPVPGPAATTEVPDVVIEAEDGNGSLRGESVASSSTSVTDSILQYRIENGRTYHKYKDGKYYVPNDARENDRLDIQHNMFLLTFDGRLGTAPPNLEGAKVNRVLDLGTGTGIWAIEFGDEHPEAEVLGIDLSAAQPEFTPPNVKFEIDDLEEEWTYSRSFDYIHSRMMTSSVGDWKVYLKKCFDHLTPGGYVELNEIDLNPGCDDDTLKPNSVLYKFVRLWGEAAAVFGRPFQDIKGLKDVLVEVGFVEVHIQRFKWPSNPWAKDKKHRELGYWNYDNFAAGLEGFVMAPFTRAHSWTPQEVTVLCMEVRTEMNNPNIHSYSSIWSIYGRKPEEAATPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULY1</accession>
    <name>A0AAD8ULY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364274.1">
        <property type="nucleotide sequence ID" value="XM_060514264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULY1"/>
    <dbReference type="GeneID" id="85398162"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="198" mass="22614" checksum="7EA0C3A6A17A6355" modified="2024-05-29" version="1">MAETSLLDKLPGEIRNKIWKLLCTPLPCRPNRERAGPTTGILNCNKHLCQEFSSFLFHQNSNGEIPDLTIVITTTCRKGARLLLAIEPKCAMSETCFHFDERIDKAGCFDVNDMENPVFDVLREAKQINMVHVRFDGPWFVNEAPLYSLPGTRRARFGEDPIYDAEAFWRKWDVPFLCHLAKARDVARLLGSFRASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM76</accession>
    <name>A0AAD8UM76_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_229838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366942.1">
        <property type="nucleotide sequence ID" value="XM_060501802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM76"/>
    <dbReference type="GeneID" id="85385701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053203">
        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022024">
        <property type="entry name" value="DUF3602"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34693:SF1">
        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12223">
        <property type="entry name" value="DUF3602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="154" mass="15932" checksum="3487559DA71E1EAF" modified="2024-05-29" version="1">MSDVFRKVGRGGSGNFFSKKDVDDAEKANTESTDVAASSTSPTSTGYVRAGRGGSGNYVDPTSLPGTKQQEELASKTQAAVNASIARSAARGASGRGGAGNYTGGVVPGAEATEEEEVKRKEALEKKIIEDVEAGLPMPPKAFHHTTKKEEEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM97</accession>
    <name>A0AAD8UM97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YkoF-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_650002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366972.1">
        <property type="nucleotide sequence ID" value="XM_060510335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM97"/>
    <dbReference type="GeneID" id="85394234"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051614">
        <property type="entry name" value="UPF0045_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00106">
        <property type="entry name" value="MTH1187 family thiamine-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33777:SF1">
        <property type="entry name" value="UPF0045 PROTEIN ECM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="MTH1187/YkoF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine-binding protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="115" mass="12278" checksum="529134A0439D1A85" modified="2024-05-29" version="1">MTSEDYSNIPTPKAAYADFCLIPVGTGSVSVANEVAQVQRLLKASGLKYAMHSAGTTVEGSWDDVFRVIGQAHSLVHQSGVVRIQSSMRVGSRTDKKQSAADKVARVEGILAQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMG7</accession>
    <name>A0AAD8UMG7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="1">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_622164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364725.1">
        <property type="nucleotide sequence ID" value="XM_060508315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMG7"/>
    <dbReference type="GeneID" id="85392214"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="2">
        <location>
            <begin position="42"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="427" mass="46864" checksum="1B3F7ABBF8FAAA17" modified="2024-05-29" version="1">MTWLALRSAAFARVPATTTCLPGARLYSGATTGAGRASDPLRILFCGSDNFSCAALTALTAESKRNPALIESLEVVVRPSKPSGRGMKNVREVPLRTLAQQLKLPIHVRDTFTKWQPPSDFNLIIAVSFGLFVPPRLLKMAKYGGLNVHPSLLPEFRGPAPLQHTLLQGRTHTGITLQTLDHKAFDHGDILAQTPLPGIPIPENCTTQQLLDVVTPPAAEMLVDGLRRGVHVPPHVNVGWAYSSSNFEEDSNKAPPHAPKITNHDRWIAWSEWTAAEVATRQRVLGGVWSSAVNQTTDTEKRIKLGRVEAVPLEDMPEHIKQFTRLLRVDKKDRTIASDATPEDGTNVKLVNWIQGTQDGHRKVLQCPFFEHEDGKSILIPFVEGDKVLKVSTMIVEGSAERAAVSAIKSFAVVGDGRHWELTPSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMS8</accession>
    <name>A0AAD8UMS8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Involucrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_219776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367257.1">
        <property type="nucleotide sequence ID" value="XM_060501749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMS8"/>
    <dbReference type="GeneID" id="85385648"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="56394" checksum="41548B6D852893E8" modified="2024-05-29" version="1">MTKDKKLGRMSTTPAEKRRSFIPGGSSSSNNKEHNSSGGSSSASNSNAAGGPSSSSAKPSSSSSQHGGGGSSDAHHVLHTSNPRTSAANIIAPPPRAHHGPANSSSASPNPEDGVTAATASSSSKDAKDKESRHKEASGGASSNSNAAGTAAHGHSGGTSSSSSSSQIKDARIAHLERELEIMEREFTKELDKLSQNESETAVFWQAKHSDVNQQFLRADADLRLLRQESEARDADRDALRREVSELRVQVRGLKEFVSTSTRTSGQTSDEVFCDGMARLSNGLQNWVIVNFRRSKLDFAAASDDVLEELGQLVPMYADLESSAKVHMLQSVVSRVLVDTIFNSYFFGLPKEQAEQLKAVEQTLSGYVDSAEAINNWRSTTLALLQREADSKMQAETLAATDRVIARVNRILDAVTDATPAPPATGETTNPRDAGLRALVGSAADLARQLAVQKAVFRVHMPDIVPHQQTSFDAATMEDIGGEDEEALSQRDIACVTFPGIIKRGDENGGHMQYQNVIAKARVLCSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNF5</accession>
    <name>A0AAD8UNF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_320063</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365054.1">
        <property type="nucleotide sequence ID" value="XM_060502368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNF5"/>
    <dbReference type="GeneID" id="85386267"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF35">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="56492" checksum="FEF74B6E6EC421B7" modified="2024-05-29" version="1">MSGVLGTGAYKRYFGNPTSYRQGGITASMPAGSLVGSLVSSFIADKYSRKVALQFSCILWTIGAILQCASVNVGMLCVGRVIAGMCVGIASSIVPVYQSEIAPKEIRGRVVSLQQWAITWGILIQYFIQYGAAEGIGKGSTDPDQPTAAFRIPWGVQIVPAAVLFVGLFFFPYSPRWLASKDRWDEAIKVLAHLHGSGDVNHPKVLAQYQEIEEALRFEREENISSFKGLIAPRMYKRVLLGMSIQMWSQLCGMNIMMYYIVYIMQGAGIGNPLLTASIQYIINVVMTLPAIVFIDKLGRRPLLVGGSFMMMTWLFISGALQQYYGQPNTAETRNPDNESVTWLVLNQRPVSSAIVSCSYLFVATFATTWGPVSWTYPAEIFPSKIRAKAVSLSTSTNWFWNMILAFAVPPLLWNINYKMYYIFATFNALAFLHTAFFAPETKGFTLEEMDDVFNSGLPAWKTHQKKSRLDDIEREIAAGNLKVTRHGAVADEDNHEVVAETEKKGTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNG3</accession>
    <name>A0AAD8UNG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_621930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364848.1">
        <property type="nucleotide sequence ID" value="XM_060508298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNG3"/>
    <dbReference type="GeneID" id="85392197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000254">
        <property type="entry name" value="MAL31p Maltose permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="63"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="555" mass="61084" checksum="407D52697322235D" modified="2024-05-29" version="1">MATTPVNVETANALTDPSAAEKDSKHEPVLLDHVAHDAQAATEGQKNMSVMESFRAYPKSVAFSMVLSLCIVMEAYDTSLIGNFYGLPQFRRRFGVRLENGDYQLTSTWQSGLQNATQVGQMIGLFIGGIVAERYGYKKTFLGALVLNIAFIFLFFFAQNIGYLLAGGLLCGLPWGAFQALTTTYAADVTPMALRPIMTTYTNMCWVIGQFIGTGVLRGLLSRPDDWAWRIPYAIQWVFPLPIMVGVVLAPESPTWLVRKGRLTDARNALRRLASSSTTDAELDVSISMIAHTNEMERLNSEGTSYIDCFRGTNLRRTMIACFVWVGQVACGIWFGGNVIYFLQQAGFDSDNSFSFGLGTSAMAIVGTFLSWFLLPHVGRRTLYVVGLCIMFTVLVTVGGMGIPAPRPDLGWASGALLMVFVITYDMTVGPTCYCLVAEIPSTRLRIKTVAIARNAYLLASIGANFLNPPIINPSAWNLRGKGGFIWAGICFCELVWAYFCLPEPKGRSPAELEMLFENRVSARNFAQAKVEVFADNVESDEKHDGPMAVNVEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNL3</accession>
    <name>A0AAD8UNL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferric reductase NAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_621120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365159.1">
        <property type="nucleotide sequence ID" value="XM_060508240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNL3"/>
    <dbReference type="GeneID" id="85392139"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="10">
        <location>
            <begin position="116"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding 8" evidence="11">
        <location>
            <begin position="282"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="12">
        <location>
            <begin position="367"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1725104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="556" mass="62504" checksum="3AA0D5BF5DF07E10" modified="2024-05-29" version="1">MVQAFKSPKQKANEDTLHFYVAFLFGLVFLTFVAYWLREASNKNPCSKSAQGLKGPGRQACVDFFRQLERRVDWGWFGRPSFGFIAMVGVYIVVNVTLCSTNIVMRRLLNHWASRFGWMCAANMTLCIFFGMKNTPLTPMVGVSHAQLNILHRIVGYTAVLLLALHAIFYTMHFHRYGKLASLLKPEDLAGIGAAIGMIILFLGILRHRNYELFYISHIAGFAAAVILTGLHRPNWAKRIPALMSFSFGLWLLDRTIRASRMLYNLINNSVTFYPLPDGGTRLLLKKPGLQAASPGTHIFLWIPRVHIYENHPFTIVNNGPSGLEVVMKSHQGFTKAVSNFITCHPRSTAWASIDGPYGVCPNMDNYDKLIFIAGGSGAAFTFGLMNRILGQSERPKLQSVEFVWTVRRIEHLKWFSEHLNNLMKIGPAVRVSLFVTNEEATSSSIATPYDIAHDVESQLLSGTRAPGYGAVSSADDTSSLLARTNGHEVEQAYNLHFKRMDIESVISDAMQFVESRQRVLMATCGPESLMEAVRDSAESWRKRRDLRIDVHSEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNZ2</accession>
    <name>A0AAD8UNZ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cx9C motif-containing protein 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_622355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364609.1">
        <property type="nucleotide sequence ID" value="XM_060508327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNZ2"/>
    <dbReference type="GeneID" id="85392226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027179">
        <property type="entry name" value="CMC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15590:SF0">
        <property type="entry name" value="CX9C MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08991">
        <property type="entry name" value="CMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627179-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="85" mass="9495" checksum="71ED09C66EE344ED" modified="2024-05-29" version="1">MGQNEDLKANPPCHPRACAIQDCLTKNGYKEEKCQSVILALYECCDAFYQSKGDNATSASCPKPDLLRLKLSILREESRETVSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP18</accession>
    <name>A0AAD8UP18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_717865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367396.1">
        <property type="nucleotide sequence ID" value="XM_060511995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP18"/>
    <dbReference type="GeneID" id="85395893"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="40897" checksum="AA27F10CD90FEE23" modified="2024-05-29" version="1">MTMSPASPRRRHILSSVNPGEGHENTPEPTKRKPSPGPTDAEAQAQAEPGDGENLRPRSSRIRLKSKHSKSSRSHRHRDRDRGHDPDTVDNEDSRSEHRHSRRHHHSSRRQRRRSRSPTPPNPYEPQALDPDAAFRESLFDAMADDEGAAYWQGVYGQPIHVYSNERPGPEGELERMTDEEYSQHVRQKMWEKTHQGLLEERARREEARKRKKEEDTVNRKLQEDMERSLRRGEERRKKRAWAQLWADYTRGWTEWANNVDKIPWPVESSRRRDINEKEVRRFIVNGLGLEDIGEKEFAAKLRDERVRWHPDKMQQKLGGQVDDEAMKDITAIFQIIDKLWADTRSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPM9</accession>
    <name>A0AAD8UPM9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mannan endo-1,4-beta-mannosidase A</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Endo-beta-1,4-mannanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_670199</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365493.1">
        <property type="nucleotide sequence ID" value="XM_060511118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPM9"/>
    <dbReference type="GeneID" id="85395017"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041953327" description="Mannan endo-1,4-beta-mannosidase A" evidence="12">
        <location>
            <begin position="18"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="13">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="433" mass="46406" checksum="8344431F8EEE5110" modified="2024-05-29" version="1">MKSAVAGALALAAAVSAQAPLYGQCGGQGWTGATTCVSGSVCTYSNQWYSQCLPGSAATTTSRSSTLATSTRAATTSSVAATSRTSSATTPPSTGFPKAVGTKFSIDGVAKYYPGTNCYWCSFLTNAADVDLVLGHLKTSGLRILRIWGFNDVNTIPQYDNWFQYLSASGSQINTGENGLGRLDTVVASAEKNGIKLIINFVNNWNDYGGINAYVNAFGGDHNGWYTNTAAQTQYLKYVQTVVNRYKASPAIFAWELANEPRCQGCATSVIYNWAKSTSAYVKSLDPNHMVTLGDEGMGLPGDTSYPYQYGEGTDWVGLLNITTLDFGTFHFYPNSWSVGYDTGAKWVADHAKACVAANKPCFFEEYGAPSDHCTIERPWQIASVATAGMAGDAFWQLGDTISTGQSHNDGNTIYYGTDEWTCLVTNHVAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ74</accession>
    <name>A0AAD8UQ74_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_113967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368652.1">
        <property type="nucleotide sequence ID" value="XM_060501112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ74"/>
    <dbReference type="GeneID" id="85385011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="92" mass="10749" checksum="A1674837A3D6B98F" modified="2024-05-29" version="1">MCVQYILFPPRRPGWWWDSIPQTPPIAVTFHPPPPHKRGLRWESHQHTLGLLPQKVCDVRLLATRRVPGRGEPPRRRGVGEPQRLFCLSTWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQH1</accession>
    <name>A0AAD8UQH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_731042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364655.1">
        <property type="nucleotide sequence ID" value="XM_060512860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQH1"/>
    <dbReference type="GeneID" id="85396758"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="176" mass="19515" checksum="1C61A1FF93F75D46" modified="2024-05-29" version="1">MYALSSFTRGTGRSPSLKDPNRMAIYEEIHITSPAGCCTKDPPPHRLESAVGYPYLGLATINSSESHSIGARTRVSGKLPTKPRTLEFVILNVSEVLIRNIKEICHGASFQDERFLAGVRSIPAERRDSDQNNSNSPTRLIRLLCTCITKTRYLTMHSRLDVGLVIHPMVKCCSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR98</accession>
    <name>A0AAD8UR98_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Structure-specific endonuclease subunit SLX4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLX4</name>
        <name evidence="11" type="ORF">BDZ83DRAFT_615826</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a heterodimer with SLX1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9">Phosphorylated in response to DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SLX4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR98"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03110">
        <property type="entry name" value="Endonuc_su_Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000637">
        <property type="entry name" value="HMGI/Y_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027784">
        <property type="entry name" value="Slx4_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018574">
        <property type="entry name" value="Structure-sp_endonuc_su_Slx4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09494">
        <property type="entry name" value="Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00354">
        <property type="entry name" value="HMGI_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="411"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="533"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="668"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="240"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="805"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="937" mass="101463" checksum="09E6ED5F2DF829E6" modified="2024-05-29" version="1">MGSPFRSTRHDAYKLSSSPSLPSLDQIKSQFPKQPPLRSPMAATSTPTHASHHFANPSSFLRQEQPAIDLTTPCRDEPVTTRPQEEEEEVTVISIANVPRPKRKRGVKVFEKKAFQPPSPSKPIQDASASPPWKKYAKPKKPAAKSEKKPKTAKPKAAAKKSGVQSRHFAKPKVEGKEDSPLPPPEPEKDANEPLELEAALRRRVDWTPPPADNGMASGSKSSQAIDLLSSTVESPGHAASKETFDNLFEKFGRPDEELKKPSVEPSDGDRRVLKKRKLTETLPINESSKMGPPQKGPLKVKAPRKKPRTITELATAAYVVPDATEQEQPSAPPVEIVEDGPETTKTKGKKRASKAKKPKKVPPPEPILLSPTAALRQAAKQDYVFGTSSQLAREHSPTFLRDLQSALQASNSKREDRFVTPINSDEVEPEPKQKLWDVGARDEDGRLLDLEVINLADTPQAAPGVADGLNPFGYAGTEQRVAALPAHLPSDVSFPDIEDLLAKDMAIDLPPHPVVSTQEKINAPLPAHMLSDMSFPDIDDLLGKETDQDGKPQTQKQALPSSPPPRSAEITVPSVEVLLVSSGSGPNPEEVASTLPPLESPPAQASKASKSVATEDTAPEMAKPDFGLYTDNQLAREISSYGFKPVKRRQAMLALLDQCWVGKQRTALSSLPTNRPISTTSQAQAAAKSQKLAATASPKRPRGRPRKTSLVEAEAEVEMPSSEPPPSAQQPSPSPKRGRGRPRKNPESTTATPSTASKKGKSKATPGASKEPKASRKAASPVASPPRKKTKVTKVIEIPDSESEGPLSLSPSPCSSPEPTFSPAPEEASVSIGDDTEMSLAASQSQRSEVLFVRITEAVTSAPPTTDSKNPSFHEMMLMYDPIVLEDLAGWLNTGQLSRVGYDGEVSPSEVKQWCESKSVCCLWRESLRGKERKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URE5</accession>
    <name>A0AAD8URE5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_577264</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365105.1">
        <property type="nucleotide sequence ID" value="XM_060505004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URE5"/>
    <dbReference type="GeneID" id="85388903"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="210"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="403"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="419"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="51702" checksum="DB2C85132621348D" modified="2024-05-29" version="1">MIGTVLFGSTYFFMVMFQCRPIQTFWEESPRTDGKCFNNRVVIIMTFTASIINCLADWAFGILPLFIVWSLSLPKRTRLLAFGILSFAAIGSAATVARSVYIPTLLDGDDFLWATTDVALWSTVEPGIGITAASLATLRPLWQLVWYRAGMRSQAPRAIAWRERFKGQPSYVRSDGSDPRHPRHPVPDDAPLEEIEADIRAEFEAEVPRIARSQDGYSSSAPTRRSGLSKDFNLAYERERQDDDAESLVVPRDDGDGGQWLCPSPREGDNSFELEDGLHLTPKVRSPAPTVNWCSPRMSAISMGFGSFNRDNRDSTHSALTLGVNNYDGANPMSNRASRLSRLSNVSHLHDNNNISNSNRASRLSTLNSPGNHYRNSRMTVETYTNTTNPRHSSRFDNRYSRTTRASSHYARGSQFLAPPSPGDFPMPSPPPSAWQINVPGGMDSAQWLSSRMAEHPGHPGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URV3</accession>
    <name>A0AAD8URV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_576954</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365330.1">
        <property type="nucleotide sequence ID" value="XM_060504968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URV3"/>
    <dbReference type="GeneID" id="85388867"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001278">
        <property type="entry name" value="Iron-sulfur cluster carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="32283" checksum="D4BCC1A02DEC76CB" modified="2024-05-29" version="1">MRPTLFRPFQSTLRVLGHENPLGLPKSGTPPNWPRKPVKRKITGVQKIIAVSSAKGGVGKSTVAANLSLAFARLGYRAGILDTDIFGPSIPTLFNLSGEPRLSENNQLIPMTNYGVKTMSMGYLVPEDNAVVWRGPMVMKAIQQLLHEVDWGGLDVLVLDLPPGTGDTQLTITQQIILDGSIIVTTPHTLAVKDAVKGVNMFNKVNTNILGLVQNMSLFNCPHCNGDTHVFGSNERVERMCREHKIDFLGDIPLHPSIGDDADLGKPTVVSEPSSARAEIFLKIAKDIAPKIDLRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US20</accession>
    <name>A0AAD8US20_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_269271</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366321.1">
        <property type="nucleotide sequence ID" value="XM_060502043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US20"/>
    <dbReference type="GeneID" id="85385942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="214"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1726266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="439" mass="48979" checksum="DA66981D81459E20" modified="2024-05-29" version="1">MPSATGQNWEKYQKTYADDEVEEKKITPLTDEDIQVLKTYGAAPYGAAIKKLEQQIKEKQTSVDEKIGVKESDTGLAPPHLWDVAADRQRMSEEQPLQVARCTKIIPDEKDDSKSKYVINVKQIAKFVVQLGERVSPTDIEEGMRVGVDRNKYQILLPLPPKIDASVTMMTVEEKPDVTYGDVGGSKEQVEKLREVVEMPLLSPERFVNLGIDPPKGALLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARFDDGAGGDNEVQRTMLELITQLDGFDARGNIKVMFATNRPSTLDPALMRPGRIDRKIEFSLPDLEGRANILRIHAKSMSVERDIRWELISRLCPNATGAELRSVCTEAGMFAIRARRKVATEKDFLSAVDKVIKANLKFNSTASYMQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USM1</accession>
    <name>A0AAD8USM1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_651092</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365720.1">
        <property type="nucleotide sequence ID" value="XM_060510429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USM1"/>
    <dbReference type="GeneID" id="85394328"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000043">
        <property type="entry name" value="Cystathionine gamma-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000008">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="416" mass="44218" checksum="638D6088AF7AD0EB" modified="2024-05-29" version="1">MTVPVAEHPIETPPRAPSPVHNFGTLAVHAGSPHDPVTGAVIEPISLSTTFAQTSVGKPVGVYEYSRSSNPNRDNFEQAVAALEHAKYALAFSSGSATTAVVLQSLAAGSHVISVSDVYGGTHRYFTQVAKAHGVKVTFTPEIEVDISAHITPATKLVWIESPSNPTLRLVDVRAVVTQAHQHGIMVVVDNTFLSPYVQNPLDLGADIVVHSVTKYINGHSDVVMGVAAFNSPDLKQRLGFLQNAIGAVPSAFDCWLAHRGLKTLHLRAREASTNATAVATALEASDNVIAVNYPGLDSHPHRAIAKKQHRNGMGGGMLSFRIKGGHAAAERFCQLTRIFTLAESLGGVESLVEVPSSMTHAGIPKDQREAVGVFDDLVRISCGVEDAEDLRRDVLQALDKAVAEQKNGSNGVNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USN0</accession>
    <name>A0AAD8USN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_718574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366439.1">
        <property type="nucleotide sequence ID" value="XM_060512093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USN0"/>
    <dbReference type="GeneID" id="85395991"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF52">
        <property type="entry name" value="SINGLE-STRANDED DNA-DEPENDENT ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="433"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="759"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="875"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1726384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1033" mass="116002" checksum="5620BF49423CCE7D" modified="2024-05-29" version="1">MSLKRLLNEEDEDLHYPDPSSVSSYGSITPTYQGGVQDYSYPEYHPRHTPFQSSDSTIQGGQDDFPVIDNHPPIEDVQIYDLLLDQGVDSQLGSLNISNETELASFDFGDLETWGRSTIAQAPELGMYSSPQSSESSQDSLTVTQSSSLFPDSSITGSDSCSSTAGDDDADKVCYGMLYNVDIKLIGDMGVIDTKLRESSRASAPGRIAYQRFTLTDSQEHICLSFKDDNTEFGYLRSGPGKALARLLTPDSRVEFEPIAPTNALRETIGRAKKPVEAMVKVDINVYGPRAAAKVVGDKLTEGKLWLQKSDHARRELCYENPHFLKIQGGETMPENVINDVNSGQPSGRQPREEKLRRMMIEVYDSIKNKREFNRELGDKRLKNGLLGHQQEALAFMLERESGDINLGYKLWRPVTVEGQEWYRHKITNVKQKIQPDERGGGILADEMGMGKSLSILSLIVKTLDDARNWAVEEEKNNEKSKDLHYSGSTLVVVSSALLIYNWTNEIKKHVDGSLTHVKYHGPNREKDIDKIKGSDIVVTTYNTLSAEFEKKSSILHKIGWYRVVLDEAHIIRRPATTFYQACRSLHANSRWCLTGTPIQNKLADIGALFAFIRATPFDNPAAFRRYIEVPFEQHSDNLEKVKERLVALMESLCLRRTKEVLDLPPLEERVVPLEFSPEERDQYDKTKKILMRTIKQKVGEVEKSSKFGLFQANLQMRILCNHGTFQKPFSWHRRSYRLDLDEREAAVSALGQNAELTCNGCHQPMPILGFNRLRNASEKQCPHVFCSECLDDSDLSSMATPVSGPRERHCPVCDNWKKSAKIPSTGLGTIPHVRVEGPVVDARGLPDASVQTTSGADDADYFNTVGYSTKMEALIRDVQVDVSTTKSIIFSCWTRTLRLVAKHLEKVGVKYHKIDGDCPLSQRQEILAQFAEDEEKRVLIMTTGTGAFGLNLTCANRVFIVELQWNPSVENQAIARAIRFGQGKKVLVTRYVIKNTVEEEMRSQQNVKKNLAAIGFDESGAADVDDMDIDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USW3</accession>
    <name>A0AAD8USW3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_750068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367334.1">
        <property type="nucleotide sequence ID" value="XM_060513871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USW3"/>
    <dbReference type="GeneID" id="85397769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="11993" checksum="EA257DE4CA139026" modified="2024-05-29" version="1">MKTKRANTAQGPSEILSDAPAITRQERIVITRLLGGRPSFHVNPLTEKEMAVLKTVVPRLIKASKDPLMPDADSFFDRNFETHFFIFDDALRVVMQLKACNVTYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU16</accession>
    <name>A0AAD8UU16_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_211527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367371.1">
        <property type="nucleotide sequence ID" value="XM_060501712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU16"/>
    <dbReference type="GeneID" id="85385611"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018822">
        <property type="entry name" value="UPF0646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10336">
        <property type="entry name" value="DUF2420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="815" mass="88545" checksum="7D94573114CFF7C5" modified="2024-05-29" version="1">MTTEAAPALGLEGQLHEEYIDYSEDDSAAPAVPVEGSNITSFPANAHLVTGEVEYTGTSALEPDNQTIDQRIDAEIDAISVAADASLQPGDLDPTDGPQVDGVDSISAIEAEDSYMHEDEPLAYADVAEPDDGLAAEPEISWEDGPANEEDAAQNEENEHEDNEVEDVQDENSQDESHITFEKDEWQLVEEKEGLPQGGLSPANSAGEQETEAHEVDQELADSSNDANNLDANLDVFDVADVDAGLDEQQVAEADNTEVNDLHEIDFNNGGNIATVNAVVGISDTRSEHIPDYQKTDSDFPTEQDAEDHPMGVDTGSQPEDELESIMGVATADQTNDEETHDDVVNAEDHDAVAEDSSVPEHVEFDDEVLADARSSVSVETPTHEEMEIPVITVSYKGIDYPFFYGSPDSQGKECFFNDLTLLHCKMEGVLAGFRRELANELGPFDELVFQIDELGLEFTESSQAEVFSDITLGQIISVFDSLVKNQNADASKPLYAYLTTRPNCKKRWLSLVDDAYNGKGLDEISYYFASRAQSEVPEIMDDEPDLIGEEDNADAASWPQSPAESGHGEHNLDEAEGENEEINDDDDVGDGITGEDDTQSQNAFEENPLQQDESAISMPDAEATMVDTEASLMDETTAVVDLSVVEDGGDVEDALEDQQPQENGEAAPEIDESDPLASETQDAAVLGTAIDARNTFDDEDAAVIADQIIENANESFAEKVTPDTSATSTLNGDEEVTYENELDLNADLPETEVVEAEVADEDDRLAEIDWREFSGQGDDEIAVESPSTSGKRQRSDVDDLLDAEAQQDVKRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU22</accession>
    <name>A0AAD8UU22_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">26S proteasome regulatory subunit 8 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_749781</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367784.1">
        <property type="nucleotide sequence ID" value="XM_060513817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU22"/>
    <dbReference type="GeneID" id="85397715"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000068">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="165"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="389" mass="43521" checksum="0564FBA6951891C4" modified="2024-05-29" version="1">MALDSYYQNKIEAMKLEILKGQAVLRRLEAQRNDYNSRVRLLREELGLLQQPGSYVGEVVKVMSTKKVLVKVHPEGKYVVDISDNVDITKLTVGKRVTLLSDSYKLEKMLPSSVDPLVSLMMVEKVPDSTYDMIGGLDQQIKEIKEVIELGLKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCKFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRVEGSSGGDSEVQRTMLELLNQLDGFEPTKNIKVIMATNRLDILDPALLRPGRIDRKIEFPPPSVEARADILRIHSRKMNLTRGINLTKIAEKMNGCSGAELKGVCTEAGMYALRERRVHVTQEDFELATAKILNKHDDKEVSLGKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV82</accession>
    <name>A0AAD8UV82_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase SRPK3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_665036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368369.1">
        <property type="nucleotide sequence ID" value="XM_060511085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV82"/>
    <dbReference type="GeneID" id="85394984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="52"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="463" mass="51902" checksum="8A4EF046348510A5" modified="2024-05-29" version="1">MSSPAATPPPKDPNSERNFRFHQSGTPCEWAESYRPGGFHPVHFGDIFEGRYEIIRKLGNGSFGTVWLAFDSSRNRYVALKIEVAKRKEPTEVKIYRILANKVSNDQGSKFVVGLLDYFYHDGPNGNHLCLVLEPMGPSLSSVLNAPLEMYDPRNPPVRRFESDQTKRILRHVLSGLNFLHSNGIVHGDLQSGNILFALQDLHLLDRQILKQDENDASKIDMLRRLDDKPDRWAPKYLAVSDPLSNYMLEGQNQVTKLSDLGGAFCIDDPPLSVLTPVSLRAPEALLNEAIGIGIDIWSFGCIVYELVTGAALFQLPPFGLSDSEKKDEHLIQLTDIIGPLPQTLVAKWSNAAKYYDRSGERLDTVPTDIIDEVTEDSNPDCRLEDDSSDELEDMDRSGLDLAERGPPQVQKSLEKLVKTLKAPDLGDEEEEQLILLLRATFHYDPLQRPSAAALLDFPWLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWX4</accession>
    <name>A0AAD8UWX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_649205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367895.1">
        <property type="nucleotide sequence ID" value="XM_060510249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWX4"/>
    <dbReference type="GeneID" id="85394148"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000021">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000015">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="286"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1119" mass="124157" checksum="1A1C326758B40EE4" modified="2024-05-29" version="1">MFTLSSLVQKAQQLVDPTQGLNLTNSDKNPSKSSLFQNQFRLPSTQTPLYEINAELTIPPANATYGGKDHDRGYHYAGKLHLSEGYMCFSTTPSSFVQGASTSTSSAFTGQTHGGGPSGNGFTFPLCAIRRVERLNSQTFQFALAITTWNGINQQEKKDKDKEPVPDKDKKDVREQRITIHLAGTRQGCERFCDGLKKGLRAGVGNVGKYKKVTGECYSEYLLRSDDKKNASPPDAGLGMLFRYPGDPKKLRDRAKMRLWAEYLRDNGRNMTLIRQPTFHKLIRVGLPNRLRGETWELTSGSIYLRLEHPTLYAETLAKYEGQESLAIDEIEKDLNRSLPEYPGFQSEEGIGRLRRVLTAYSWVNPDVGYCQAMNIVVAALLIYMSETQAFFLLSSMCDRLVPGYYSTTMYGTLLDQKVFESLVEKTMPILWEHLVKSDVQLSVVSLPWFLSLYINSMPLVFAFRVLDVFFVEGPKVLFQIGLAILRINGEELLDATDDGAFISILKGYFARLDESAHPKSENPKLRAVTKFQELMVVAFKEFSGITHSSITDLRLKNKDAVLSNIESFAKRTALRNLGPDSKLLAAEELGALYDRFYTILYERQQRESIIQQEKQRRAKNARPRARDVFEPSDEHVEKGRVALGASTSLMDYDAFREFLANMAKWAMSDSPTTPRRDTFADKDRNAYTSRRQNNGLLSPWGSGPEPADHEFMQQLFKKWDVSGAGVLTLADVVSGFARIKGKKDIMGTITYFFELYDDDGDGKVDREGILRISEALLFLSRRGLEGTLSPSASTLTLSTPTGQGSEPSLPGISTNERFLGSVSAFIRRCFEYADPDHPNNKIHEEEKEEAKSTENSEAFAIGDDDDEEDLLAMDSPPGSPSKAKKSFSDSLSSPTEEKGTAAGQSQRRVSKAESEAANAALDPANPLHMTLPTFRMVVLADELLEQFFESSFPTSFHLIEGLPTVSTPTSTLTTFSSLNFGRAPVVALNPAAQGATRGLRGVLDNIVTDGMRVAAEVRRRMEEAQKELEKNAVPGQQRDVEDEEDDADIGVEIGIRKGTASGSADIERRSVRSEDRDLLDGADAEAGANGSGKEGQLVDIEPTNRSETNAKGVVEFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8E3</accession>
    <name>A0AAD8X8E3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_593779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000226">
        <property type="protein sequence ID" value="KAK1706432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357832.1">
        <property type="nucleotide sequence ID" value="XM_060506663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8E3"/>
    <dbReference type="GeneID" id="85390562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="6">
        <location>
            <begin position="61"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1706432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="35943" checksum="493E7C88958839A3" modified="2024-05-29" version="1">MPRLNPLFLLSLTVALTAYMLSPTLRAFLTSVTTTLITSTSSKHTDSPKMKKPRMPVYFFSHGGPDVMYNKAHPVYPTLQHIGAEITSLAPTTILVFSAHWQSPSPTTISINAAPGPAPLIYDFSGFPLHYYSATYPNTGSPQLASRVCSLLFASYGSNISCVPTTDRGLDHGVWAGFHVAFNPSTNPLKVPLVQASLFRSEDPDAHYRLGAALSALRDEGVVIIGAGMSVHNLYDMSSDPRPMPYAVSFDDALKEAVEVSNVAERQDKMAQVCRRPDAKQAHPYMDHLMPIHVAAGAAGADRGKQLWTMKEGSFAWAQYRFGDVPKSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X903</accession>
    <name>A0AAD8X903_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_724235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358552.1">
        <property type="nucleotide sequence ID" value="XM_060512634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X903"/>
    <dbReference type="GeneID" id="85396532"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042082271" evidence="1">
        <location>
            <begin position="18"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="17785" checksum="D052095F315D4F42" modified="2024-05-29" version="1">MQLTSILITALAGLATARSTPSERRQTSTPGCRLVAPTDLNFGVADLRSGTVVTKALTFPVGPTTAGPCQLVGAFRQGFPIDQGGDAFARLDVRALDGPAAGSLVGSFGPLEVANDAVVKDTVQVVNSFSCRESLSFEFAIANDADVDVDINVAFTASELGGFFVQVGDQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAB2</accession>
    <name>A0AAD8XAB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_714266</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000284">
        <property type="protein sequence ID" value="KAK1703423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357279.1">
        <property type="nucleotide sequence ID" value="XM_060511651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAB2"/>
    <dbReference type="GeneID" id="85395549"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="269"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1703423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="60330" checksum="106D83A774DEF526" modified="2024-05-29" version="1">MRQPICGLCRRTGGSCTFPTKRKAPEVRKRPAKQTESNVIDSQRLEHLVSLLESRLDETPKSKSSTGESPGREQGSAQSSATSPSYSGSVWTCREDAEQDVIITLASTPANSTSHCLGSRAEQKVETKPRTTDKSTRETLYRPQIPEKVVTELVNLYFDKIQAWLPLLHRPNFFAKYMVDGSFQEDRLLEMSLEEGLLLHGIFALAARHSNNEYFKGLSSPNRGESFAERAIQYYGKLRSSDSETTLEYLQGCILLAFYLYTAGPSHQAWILTGVCARLAYDLDLCYMDEEDGGNEMAYTEWSAEEERRRAFWLVWEIDTFASTLSMRPRGLNSQRIVSPVIPLDPSQAWKVLLDSPNKDERAWFLVANHLMALAYEAASGPQKSQREHSNLASSITYFSLAVSQRFGLETNPPVFTAKTFANANWIVGMHLMLANTRACLHALTVAPASGDETFGDDYSRIFNRWHPEYIALSHPFLAGTLLSARTFPSTFSSRSLSSSCNQELSTLILSHFATFWKLGSVLLGECLIFHTETIYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB72</accession>
    <name>A0AAD8XB72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial import protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000246">
        <property type="protein sequence ID" value="KAK1705181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357565.1">
        <property type="nucleotide sequence ID" value="XM_060511009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB72"/>
    <dbReference type="GeneID" id="85394908"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013262">
        <property type="entry name" value="OMP_MIM1/TOM13_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28241:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08219">
        <property type="entry name" value="TOM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="13740" checksum="E65D1413C7A3E97E" modified="2024-05-29" version="1">MASDDSLHPLAESGVTIRSDSEQYSQGEDLTESPPSSNSPIILYKPPTFWGLVRGAAINLFLPFINGMMLGFGELFAHEAAFRLGWGGTKVFPLSRRTAHAIGPGLEIRDKHRRPSTGLDDLTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBZ5</accession>
    <name>A0AAD8XBZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_657455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358375.1">
        <property type="nucleotide sequence ID" value="XM_060510961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBZ5"/>
    <dbReference type="GeneID" id="85394860"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="21262" checksum="4BEB5EA193F5C0E7" modified="2024-05-29" version="1">MDPFNKLPAELRVKVGGLHYLRRSFESRREVKASEAEGNAVEEGEVKKNSEDGPGMYQMLHSRIIPNYDTLTTMYEQRAWVFLDDTGFYPSPSPNAKPHFPTGDQALDECFETIQKDEDYWDHPWQARARRRSQKWHNEMSPRKTKPEDYQDSELEENCQISLPDIVDGMYWDNLRPFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC51</accession>
    <name>A0AAD8XC51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LMBR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_108657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000155">
        <property type="protein sequence ID" value="KAK1711874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359198.1">
        <property type="nucleotide sequence ID" value="XM_060501069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC51"/>
    <dbReference type="GeneID" id="85384969"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024391">
        <property type="entry name" value="LDB19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF76">
        <property type="entry name" value="PROTEIN LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13002">
        <property type="entry name" value="LDB19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LDB19 N-terminal" evidence="2">
        <location>
            <begin position="157"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="57358" checksum="C30323BCAC4A488E" modified="2024-05-29" version="1">MPHRVANFLRNSTENFSVSAIANLKTKTKQHQQHNQPRHNNVQDEGLLRRVPLDRHSSYSSDDGEHIPYHNMFAADPADHLKEKKHHHHRLSLPFGRSNKDSHDNSHAGLDLKIESPPIVFFGDAESSTGALVSGQMQLEVKDEQLQIETFGAKLNIHVQQKRPFTNHCGECTNQYTELKRWTFLTHPTTLKKGIHQFPFSILLEGHLPASMDTPITSIAYEFKAEAILVKGTPGSQTPIKFEQNFDVKRSLPQPEFPHHSVRVFPPTNIKASAHYNQVIHPAGTHNVSFRLDGLTSANATNKTVEFWKLKKVTWKLEETIKTVAPACEKHAPVPGNANNNTQPQQKGVARTETRVLGEKYMHDGWKSDYTSTDGHVEFEFDYGVVASKHSHGPRYACDMKSSDGTEVSHALMIEMVVSKEWAPVGKPHLATQTGTGRILRMHYHVMLTECPGLGVSWDNEAPPVYQDVPPSPPAYPDEAAPVDYMSLEHLDGQAHNGLAHSREGSVTGGSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCG8</accession>
    <name>A0AAD8XCG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">XPG domain containing-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_589629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asteroid family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359558.1">
        <property type="nucleotide sequence ID" value="XM_060506252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCG8"/>
    <dbReference type="GeneID" id="85390151"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026832">
        <property type="entry name" value="Asteroid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039436">
        <property type="entry name" value="Asteroid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665">
        <property type="entry name" value="ASTEROID PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15665:SF1">
        <property type="entry name" value="PROTEIN ASTEROID HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12813">
        <property type="entry name" value="XPG_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asteroid" evidence="3">
        <location>
            <begin position="140"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="553"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="589" mass="64185" checksum="472C14696608620C" modified="2024-05-29" version="1">MGIPHLLNHLSPYGVFGPLDGHRVVIDGPALAYHIYHLCTRSTSGLPSYDILGRTAIGWLEEITSHDISIAAIYFDGFLPASKAEVRLERILKVSSSLKIFRSGFPNGCPAKQIASTRLALPPLFPSDAPKRDQPLIPPPAFLVAAIVDKLESIEKYASLVRLVPGEADAYCAEDVLRNGGTILTSDSDLTVHDLKTGSVAFFRDLHIGTIKDDKPALLGPKFSPSKIAKRLQLPEDQGMRRFAYELSKSTRPKFAQVLENCKGDVADPEEFRAFCAPYETLETTDWSAVPILGSLDKPYLDARLSEVVLQCVGYSGVAKPPAGDSGAAGCMMCLPPLLDCPARASAWDTSSSVRQLAYSLTCLLRPGGVSHVREYRRMSSGVNQGKYMAMLPRPWIKDSMDALLKALTKAKNSFSQKGSTWQAVSLQLLLAHAQEEDKLDAYLNSIKLGQSVSADSNLVPWDVVHLSAQIHATLYSLRILAQVLDLMYEVGAKDPIQGSKQLRELLSTLPSLTEYPSVDGTMRLLASMKTSGALGKVAAALGISDNLLLPSKEAKNQKKKRKKMADAEPRMRPEKKVSSNPFDILGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCK2</accession>
    <name>A0AAD8XCK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_433001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362332.1">
        <property type="nucleotide sequence ID" value="XM_060503061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCK2"/>
    <dbReference type="GeneID" id="85386960"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="113" mass="11442" checksum="E204D48B70911058" modified="2024-05-29" version="1">MDFQGSAGAPQARTCFTCGAAGHQARECPNRGAAKCATTAARTATSPAIALRSLLAARRSATSASSPDTSSPSAPTTKSAMTIGDELSASVADSVSKRFEGFEATVAHFCDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCM2</accession>
    <name>A0AAD8XCM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362392.1">
        <property type="nucleotide sequence ID" value="XM_060512900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCM2"/>
    <dbReference type="GeneID" id="85396798"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="149" mass="16322" checksum="5553B166C404207D" modified="2024-05-29" version="1">MGGKEGKEGRKAQRDDNSCSPKRKWAGPGCEKGGRGRSLRRMDNGDFCTSYGMLLQIDSGSGRMSGKVGPRHLTPSNASRPGLISRLETRHSTLDTRARSGAWKLGQTFARQWLMAAMLQHPSPSKRDMGIVRTDYCVAYPGPNVKGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCS5</accession>
    <name>A0AAD8XCS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_73562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359993.1">
        <property type="nucleotide sequence ID" value="XM_060512971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCS5"/>
    <dbReference type="GeneID" id="85396869"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="316" mass="36035" checksum="C27C819F6C44901F" modified="2024-05-29" version="1">MSSNDRNMWPTGPAGPIPGTAEYLNCLVDSTGKCKCLSSRPKAGDDLKLPRFLSFFTEMAVQEAREISLVPEHPMFEREINAPETGPFRPPMSRLDTRNICTDCYKKADPEGFTTWSLSYEKRTFQYGTFPPQITAGSPIDADSYLRERLINLPSFDARVIFRKMAHDGRPIYIDRLHGETKWIPSLTDKIERERQNAAINRENGAAYMSATRIYRADGDFGAGQNTTAEHRVGYGRLAVVRPDWRLAMPRSDSPPEDLSNPATKMEEPSEDEKEASREITGFRLIRRDIPREWLPPGPYAVYTYYMENSHGQWPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD43</accession>
    <name>A0AAD8XD43_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_635589</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360338.1">
        <property type="nucleotide sequence ID" value="XM_060509191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD43"/>
    <dbReference type="GeneID" id="85393090"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07628">
        <property type="entry name" value="BAR_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06863">
        <property type="entry name" value="PX_Atg24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000035">
        <property type="entry name" value="Sorting nexin-4 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000042">
        <property type="entry name" value="Vacuolar targeting protein Atg24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="14">
        <location>
            <begin position="60"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1715539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="480" mass="54811" checksum="0AF44E36AFFC8B7F" modified="2024-05-29" version="1">MAVMDQHQDDFSNVSWNTDEHTAAESSSSVTATEYDEDADRNGHHAYESDAPGNDDDREVLDCTVSEPLKENEGSKDTFVSYLITTNTTFPSFQRSHTTARRRFTDFVFLYKALSRDYPTAAVPPLPDKQRMEYVSGNRFGPDFTNRRAHSLQRFLNRLSLHPVLRRADILHIFLESPDWNATMRSRSLRGSQSSDAGSSGVFDNLTDSFLNAFSKAHKHDKRFLEVRERSDKLDEDLAHIEKVVARVARRENDLELDFKDLAEQFQKLITLEPGVESEVRHFANSIEDTAMGLRKLKDVTDGDYLGSLRDMQAYSTALKSLLKAREQKQVDYEQLTEYLNKNTVDRDQLQSGHGSGGLSGASGRLMRKLEDVRGVDHEQARRDRQRKLEMNIDKLTTEAERAKKTSEMFDDEVVKEVADFERIKRVEFKKQLGGLADSHIEFYDEVTEIWESYVKAMEDEGVSGTRSTGVEPPGRRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD96</accession>
    <name>A0AAD8XD96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_656384</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1712989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359605.1">
        <property type="nucleotide sequence ID" value="XM_060510872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD96"/>
    <dbReference type="GeneID" id="85394771"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041767017" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1712989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="519" mass="57056" checksum="2D684D03BB4836FD" modified="2024-05-29" version="1">MRGSRSSVFQLLLAVGSARAVTPEDCASFGSRLSLPNTTIHETTFITAGTNISLPDNHPSCAIPFQISSVDICRVVFVTTTGPRSNISLEAWLPSEWSGRFLGTGNGGMNGCIKYGDLNYGATHQFATIGTNNGHDGTSGAPFLNNPGVIEDYVYRAVHLEAQLGKEIAQQYYGKEHTKSYYLGCSTGGRQGFKEAQSFPEDYDGIVAGAPAFDLIALMYWTGQLFLKTGTNETSRFLSPAEWELVYADILKQCDGLDGLEDGILEDPSLCQYRPEGLICAEGSTDRCLSGAQAATVRAIFSPVYGLDGQYIFPRLQPGSNATARLLNGQPHQYPLDWWRYVVYNDTKWDLATMTPEDYAVASKQDPWKVSTWEGDLSAAKDRGVKVLHYHGMQDNAISSDNSERYYNHVSRTMNLPSKELDDFYRYFRISGMAHCRDGTGASMIGGNPETFASYDPDANVLAAIVRWVEEGVAPNFILGSRLTASGEVDLQRKHCKYPTRNVFKGQGDPTKPDGWECV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE64</accession>
    <name>A0AAD8XE64_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_635436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360370.1">
        <property type="nucleotide sequence ID" value="XM_060509177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE64"/>
    <dbReference type="GeneID" id="85393076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040746">
        <property type="entry name" value="THO1_MOS11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18592">
        <property type="entry name" value="Tho1_MOS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="33"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1715571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="271" mass="28732" checksum="EB8574CD663F644F" modified="2024-05-29" version="1">MATDYSSLKVPELKKLLQERSLPATGNKLDLVNRLKENDAQSAPVAAEEDEIDYSDDEPTVPTKAAEAPKPAAEAAPAAEEPKPAAAPAVAEPAAPATEAAPAPAAETTAEEDKKTEETAEAAEAAPKEDFALNLDATDAAAEAKKRADRAKRFGIDEDEEAKKKAERAKKFGVEVGSVAGLDSALPERRPKRGRPERSDEQPGRDAKRQSTDGRGPRGRGGRNNRDGGRPGGRRQGGGREGGGERDTRRSAAIDPAEKARQEARAKRFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEG6</accession>
    <name>A0AAD8XEG6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_39449</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360685.1">
        <property type="nucleotide sequence ID" value="XM_060502812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEG6"/>
    <dbReference type="GeneID" id="85386711"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000272">
        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000920">
        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="85"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1019"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="823"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="904"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="823"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="904"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="926"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1716755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1203" mass="134442" checksum="155A61ACD4C3B569" modified="2024-05-29" version="1">MDSVAFDINDALKHYMSDPASIPTPEADGSLFDYENDPEGLTAAVINPVLNPIVDAVAENPEAITRSAHLDSLQFLLKYTAFLPPQVLSKIFDLIMSGLAAEGDAINHDLESPDEQETLAHHKQLLEIYGFLLQWTIAAVETKAAEKSSTAPVARGRGKPKKNAPRDKDGVWDSATQLQSALDIMSKVLKLKLTKIFLTTSERDTFIGLLTRPVYMVLESEQRVKSTSIRMHAFKVLCIAVKHHGHAYAAQISIVQNLTYFEHLSEPMAEFLHILAETYDYPQLADEILRELSNKEFNSNDTKGPKSVSQFIVKLSELAPRLVIKQMTMLAKQLDSESYTLRCSLIEVCGNMVAHLVKQDERGENHKSQLNAFFDVLEERFLDINPYCRCRAIQVYVKLCDLEQKFPKRRQRAAEMACRSLEDKSSHVRRNAIKLLGALIKTHPFTVMHGAQLSRKEWQARLDKVDEELNALQPPEGAPGLGEGADTTVDQQLLDDATQIEQSPQKPAPMSDEQKFEAVRKAREEAATSEAIEKLTLTKRYYSEALKFIDVLHEATGTVCQLLGSRNKSEVIEAMDYFEVGDAYNIEQNKVGIRRMLRLIWTKGNSDEGKGVQSHLIDVYKRLFFEAPDSFTSNDAANFIARNMISLTFGATPAELTSLEQLLSTMMKQGLVPEIVIAKLWQVYGVQKREISRTQRRGAIIVLGMLATANPEIVVGEMETMLRTGLGSHGRADLQLAKYTCIALRRINPTGRQAKESTVKFSRLPNDHAVLSKLASITEVPSESKEWYGVAEQAINAIYAISKHPDTLCSDIIRHKTKQVFAAPRSRSASQASSQPSSRPVSRDEADSVSVDEDGNETIVAPAPQPKKRDAAVGLSQLLFIVGHVAIKQIVHLELCELDFKRRKQEQEKEKTADKSTAQAGKKDEPDDLDLIGGTTEDDFTEAMAHIRERELLFGPESLLAQFGPLVSEICANNTTYADKGLQAAATLCLAKLMCVSSEYCEANLPLLITIMERSADATVRSNAVIALGDMAVCFNHLIDENTDFLYRRLADKDQSVKRTCLMTLTFLILAGQVKVKGQLGEMAKCLEDEDRRIADLARMFFTELSTKDNAVYNHFVDMFSLLSAEKGLEEESFRRIIRFLLGFVEKDKHAKQLAEKLAARLTRCETERQWNDVAFALGLLQHKNEDITKTVSEGFRVVQLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEZ2</accession>
    <name>A0AAD8XEZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_741782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363941.1">
        <property type="nucleotide sequence ID" value="XM_060513094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEZ2"/>
    <dbReference type="GeneID" id="85396992"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050829">
        <property type="entry name" value="CorA_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47685:SF1">
        <property type="entry name" value="MAGNESIUM TRANSPORT PROTEIN CORA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="924"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="986" mass="114924" checksum="EC6CCC04D6ACDC5E" modified="2024-05-29" version="1">MGDHGSSPTCLSAEPHGPAERSHGTIRDHAAHYFGCIEIADRVNYLSREKNWELWDHEIQIEAERLQQRKPTTSEEERLKTATEKVEARIKSLAVSIEAQYKRTDILRKALSEVRCPQCEDQPRDKHGGNEGNPHPPCDLVHLVSHSHEEWKKSRSYKKGIEIIRNWKRHKTSSAQSSDVEDEHLTNSPDLSSNGRARMAPEREEARKIIRNGHIDVDYAFEEDENTPSYELERDMNGYLIQWKILRPGESRKKLDSNTPTKISPTSPNPPQLPSLPPSPLQSPRTRTARAQSEATVQFEATDHKPKRRPTGPSRLRSGTMQSASYLEPYTEQEKYLEPLSESLSDYRFKGKFPDQRLTLQNLLDPTPKRPEFRDVILSRDRPNKDGSPNKDERVRYFHIPHNNMQLKTHSRMVLRPEYWRGQQHGGRRTLVHARHMRAICERISSRIWEVEDNPDNLVLFMPYLHWEEDRKRDNMAKIIDKASEKNREEHEKQRNDARAQRVRERTYKPTTTNNKQVRNLLEPDLCRIKHHDKVSPIHKESILSAWKKNAGGNPNGKTMADVASGFASEGPVEHEHGSDDHNLWSVPKLKCSDHGRLQIENKLGQFLLDSARLYEAMSMYRDQCLSYYWTLKTTKARDRDQVVYRGTTMDERNIHRFRERRGDPAQSCQDKKPFWPSAAPSSPEQNPDFDVTDPSESNFGRYKWDGHWTKTDEDGCDHCRDEIRKVSRIVMVDQLWMWILDKQTIITSFPKRYGANKSDPSGVHKSIRTRIKHARKNQIRSVFDVALIILDECSNTFFDRTKTPQNKQTVSFQHLWHWTEQASKVYHSKSAFEDTSHLHVPLLNINPEGKLQREIKDIIDELDIMIHVNGKQREVIKRFVKHVENIYDPSGKWRDETLSPDGNRDYFRSRSISQSGEEIGSTEEARKQEEREKDEFTWFRKQAYDLISDVDDRMNELESLRKSAETTSQGVGSFTNTFVYPHADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFC4</accession>
    <name>A0AAD8XFC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycolipid 2-alpha-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_732433</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362798.1">
        <property type="nucleotide sequence ID" value="XM_060512897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFC4"/>
    <dbReference type="GeneID" id="85396795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF7">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042162786" evidence="4">
        <location>
            <begin position="32"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="55669" checksum="C8F7C3144FC44A45" modified="2024-05-29" version="1">MAAHSQLSLRSCASLVFWIALALVQVPLALCGPAHIHDTSPRAAFVSLVSEQQKEQMVASVAQLEQRFNHKYRYDWVFFSHEELSEEFKDATSNATASTVTYNLIPQQHWTIPSSVDPGRFEAGLGVNADKTLIKTAHHRRRWSAGLFAREKRLQAYEWFWMVEPGTKFLCDITVDVFRLMRDRGIAYGVNEVSFEGAADSELLWKSTKSFMDTHPDMVRPTADITWILGNSTKANKPTRSSDYYVDGTEDMESSYLGLEDEGCRAIRQGDMPPGVFLEADPQQCEPNTVADAFTTRLAASYDQCDMDTPIEIGNLNHFRGPEHSSYFDYLDNAGEFYYGNTSNVPVHSLSASMFLPRDKFWLLGDMVCKMHGLHSCPPMPHPTFNSNLQTGSNPNDLAEVVEASWFSACKDNQVLLIHRVWERIASDMARQRGIPAAQLGHTALDERNFKLYKPERYPVDVTLTWYSLEDSWRSWSCDRLKWFLGVLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFH3</accession>
    <name>A0AAD8XFH3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_356164</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364391.1">
        <property type="nucleotide sequence ID" value="XM_060502551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFH3"/>
    <dbReference type="GeneID" id="85386450"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000069">
        <property type="entry name" value="Seryl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="246"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="346"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="362"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="439"/>
            <end position="442"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="518" mass="57187" checksum="E0C4BEC908E3E7EB" modified="2024-05-29" version="1">MGRDPTSLLRSSLGAAGRRLLLISPPTPRIISRVNCVASQQSRAFADVKRPSTAPKPIIDIRHIRENPELHEQNCLERNYVQQSKSPTRINEIFAQWQALQKDSRAVRERSNLLRRQIANPASTSGDDNAEFNEIRAKTRDELLEEARVLKQKLAAVEQDEAKLVEEMEALALAIPNLTSDVTPVGDEPRLLSYINEHPHETPSASDKVWRSHVHIGSELGLLDFAGAGTVSGWGWYYLLDEAAQLEQALVQYALAVATRHGWRQVAPPSVVYSHVAAACGFQPRDQNGEQQIYSLAQSAADAERGKPELSLAGTSEIPLAGMKAETTLDATELPAKRVAVSRCYRAEAGARGASTKGLYRVHEFTKVEMFAWTAPDADETVDVFEEMLDIQTEILGSLGLHCRVLEMPTADLGASAVRKCDIETFFPSRQEQNDGWGEVTSASICTDYQTRRLATRAKIDGKLTFPWTVNGTALAVPRVLAALLEAGWNEQEMSVSIPACLQPWMDGKEKIVRKTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG16</accession>
    <name>A0AAD8XG16_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_322336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364946.1">
        <property type="nucleotide sequence ID" value="XM_060502380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG16"/>
    <dbReference type="GeneID" id="85386279"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="94"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="640" mass="72638" checksum="567C166830EAF189" modified="2024-05-29" version="1">MSLTTMARPNEIDETFSNLALDPSSPPLPLFTKPAKSPLRTLFTRKSPLPLQTTVLPYIPLKQHEVRLVNLHAGSPSSPITLTTEITALPSAKYTAFSYVWGDPFDTLPLHVDNHLFHATRNLHSALQYIRLFLKPSQIVPLWIDAISINQSDIAERSQQVSQMREIYTSADLVLTWLGPDLAPGLTYLRELGDHALAVSQNRKEPPKLLPSHVKDRYTTIREIVRVFQSTYWNRVWTVQEYTAPTDLGVFLSGTAWIDRTAFLPATILYTQALHWLRDGLRRRGADASFVDATLARVKKVVHDLKMSYARMAESNDLIRMSAETKVSSKAEGVGQVKSRHRETSTARRFNLISLLLRFRDLQATDPRDRIYAPLNLLDHGARKDPIIPVNYSLTVKQLYISVAKSLLENKDYWPLSILEICRFGSSDLPSWVPDWQVLPRKVLSRDVTTGEQVLCASRGYHTNTKPWEMLDEARLQITAMQVDVVTEAWEAFDALSVPRTKSYPTYTLRNPSEKYAIGEQTVLEAFHGLAGIEPRSEDDEEVESYYQEDWHRNTGMMSRFNRRRLIRTKHGLVGLAPAEAVQGDKIWLVPGANMFYIFRPVADDGSHTLIGEIYFQGLMNGEARGFLGDARKRTVITLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGI3</accession>
    <name>A0AAD8XGI3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_718077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367179.1">
        <property type="nucleotide sequence ID" value="XM_060512023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGI3"/>
    <dbReference type="GeneID" id="85395921"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="24484" checksum="10A3F99FBA5E8F4C" modified="2024-05-29" version="1">MPIEIRTALESDLRRCAEVGHVAFGKSPFTKIMFPGHVPKDGFLGLRTTDLIRQLRDDPTVRMFVAVDTERRGDCAIVGFAKWHVYEHGMPLSSGKLHSWGKSCNEEACSLVFGGVGLMRDRLMAYKPCVYLHILVTEPQYQHRGVGQHLLAFGIQESLRLEVPIYLEATEAGHSLYQKVGFDDIEVHRADLTKFGENRPHMIWGMIREPYSWFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG4</accession>
    <name>A0AAD8XHG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_203199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367462.1">
        <property type="nucleotide sequence ID" value="XM_060501663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG4"/>
    <dbReference type="GeneID" id="85385562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="201" mass="22818" checksum="EB017856A1A9D059" modified="2024-05-29" version="1">MWLISRGHNGIGLAFGSSLVVDIRTSVLSLVELMISLPARTRYAVMPRFGRTRSTKRSSSTSSLSRVGEERYIKTGRESPKTMPKKRKKLQKSNRPRAKSGNNGDMVGGRWLQAAAQRSVQWWRQCRGRRHSLEARRQKKPRLVVSSPMHMGSSRTALVYSALPVLPELGSGPQDTRKLGLQWEALESHPIWWTGERQDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHH2</accession>
    <name>A0AAD8XHH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_626123</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363565.1">
        <property type="nucleotide sequence ID" value="XM_060508541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHH2"/>
    <dbReference type="GeneID" id="85392440"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="8">
        <location>
            <begin position="37"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="658"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="719"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="735"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="778" mass="85962" checksum="677C52B55FEBE090" modified="2024-05-29" version="1">MESIARISSLLESARELTLDAASATRSSRSTGRPLDRTQIKKLLDSRNEREVLDGLRRVLSMMYRGQKTLPFFSSVVKNVASPNIEIKKLVYIYLIHHAEQEPDLALLSINTIQKSLSDTNPQVRALALKTMSGIRVPVISQIVSLAIKKGVADMSPYVRRAAALSIPKCYRLDPTQLPQLLEYLTALLGDKQYFVAGAAVSAFLEICPDRIDLIHPQYRALVKKVVDMDEWSQLATLRMMTYYARKCFPRRTRSVKIQEKTANLGDFYGETSQTGGEEQEVAVVDPDLALLLNGIKPLLQSRNSAVVIAVTRCYVDIGTPEYVKTAIGPLVALLRGPQDIQQVALYNIVSVCLTRPTDFVKYASHFLVRATDPAQVWELKLEILTLIFPHAPPHIKSLILNELEHFSGSTNKALVREAVRAIGRCAQTDSSAAPRCLRLLLGQITSLDGTLAAESLTVIRHLIQQDPQGHVGTVVRLAKNLDSATDPQARATIIWLVGEFSGLEGEDNIAADVMRILLKDFASEAEVAKGQILLLAAKVYLHHVNRLNESKGEDDAPVPVQDDHPVAKLWDYALLLVRYDTSYDLRDRARMYRALLSVPQLATLMLLAPKPAPQAPSPSETRKGFMLGSSTLVLAGGGGIHGLRGYDALPEWVVEGSEPDRRLRETEATSSYGEDKNVPASQMLDSAVRAAPTRTNGLGAVVGAGAASGVGVKTLDDWLAEEEKEEQQSAFHMDEEEDDEDDEEEEEETDDEEEEEEDDDDEEEDDEEEESSDDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI32</accession>
    <name>A0AAD8XI32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_619821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365573.1">
        <property type="nucleotide sequence ID" value="XM_060508154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI32"/>
    <dbReference type="GeneID" id="85392053"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="13028" checksum="F3F8607A423225D8" modified="2024-05-29" version="1">MYLALPVHTWPCLPWLGAGHTDTALTEPSYYAVLALVLRPVRRRLQCCKLEGRSRFGLINHLACPGAAMHSTCSQNAMFIRDLGGICVVPSPTQQLSCPHLTKASLSQCRVQPGNRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR7</accession>
    <name>A0AAD8XIR7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_615433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366593.1">
        <property type="nucleotide sequence ID" value="XM_060507894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIR7"/>
    <dbReference type="GeneID" id="85391793"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="22792" checksum="07DF04BFC277DD7E" modified="2024-05-29" version="1">MVLGLLVRAESEEGACGSRRGGWMKQILRRCGEGPAGWDVCAMARSSASDARYRDVVSQPQLLLARREMSFTRKVNSLRRWTRRRMRRCGDEEGALIWLGECRNRGDLPPPRVENGRKEDAYLRIDRVGMLTGSGDQRSKAEYEILFEGLRCAARREQPRKYMHGTRIEYATRHRGFPLGFLSMTLGTRGGRERKVNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIY1</accession>
    <name>A0AAD8XIY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AP-2 complex subunit MU-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_577233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365275.1">
        <property type="nucleotide sequence ID" value="XM_060504999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIY1"/>
    <dbReference type="GeneID" id="85388898"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="49192" checksum="DE84DE67B3E78D7C" modified="2024-05-29" version="1">MLSGILIFNQKGENLIFRAFRNDCRPRLADVFRIQVISNSQVRSPILTLGSTTFSHVKHENIYLVAITKSNANAALVFEFLYRLIALGRGYFGKFDEEAVKNNFVLVYELLDEIIDFGYPQNTETDTLKMYITTEGVKSERAAEDSAKITMQATGALSWRKADVKYRKNEAFVDVIEDVNLLMSATGAVLRADVTGQIVMRAYLSGTPECKFGLNDRLLLDNDGLLSLPSGNRMGTKATKAAAGSVTLEDCQFHQCVKLGKFDSDRIISFVPPDGEFELMRYRATENVNLPFKIHAIVNEVGRTKVEYSIGIKANFGAKLFATNVVVRIPTPLNTAKITERCTQGKAKYEPSENNIVWKIGRFTGQSEFVLSAEAILTSMTNQRAWSRPPLSLNFSLLMFTSSGLLVRYLKVFEKSNYSSVKWVRYMTRAGSYEIRQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ7</accession>
    <name>A0AAD8XIZ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_570176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368651.1">
        <property type="nucleotide sequence ID" value="XM_060504273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ7"/>
    <dbReference type="GeneID" id="85388172"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24000">
        <property type="entry name" value="ASKHA_NBD_HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF24">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041973724" description="Phosphotransferase" evidence="7">
        <location>
            <begin position="39"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase N-terminal" evidence="8">
        <location>
            <begin position="77"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="9">
        <location>
            <begin position="272"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="58060" checksum="E692EB45880F63BB" modified="2024-05-29" version="1">MATFPKSFLAAVVKQLLRGKSLIQALLAFWLTPQAVSGKPTTSKVDCCSTSGTTTPSGQSIEEYLKEAEHLLLGPLLDNDGLLELSNALKAQFRDKLQTSMACMLPSYNHQLPGGHEVGQYLAVDVGGSTLRIALVELRGRDAVGRESEIVRMSSFKIDNDVRNLEGMAFFDWMAERIWDMVSQDGQDPSRPMPMALAWSFPIEQTSLKGGRIHGMGKGFLAAEGLMGQDLGEVIETACAARGLTGTRLRVILNDGGATLLSQAYVHPATRFGLILGTGVNIAAYLPVSLIGRAKFGDRPREWWSEARDVIVNTELGMFGGGGVLGVTRWDRLLKQGHPRPDFQPLEQMVSGYYLGEVVRFALIEAIRTTGVFGGVVPKSLDEPYSLKSETISAIEGDTSPSLSSSIDLFTAQHPSSHTPTPSDLAALRSLASFVSRRSAAIIAACLHAVWSLRLESLAEEKETNTKQTAIQKETSLSRTMVAYNGSVIECYPGYLAMCQSYVDALVNRGDRSVELVPAKESSLLGAGVALARACDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJB0</accession>
    <name>A0AAD8XJB0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_197576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367673.1">
        <property type="nucleotide sequence ID" value="XM_060501640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJB0"/>
    <dbReference type="GeneID" id="85385539"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000273">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="537"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="640" mass="71343" checksum="2163176E3689259E" modified="2024-05-29" version="1">MSDQQQGAGWLSFANPHDPGATDPTLLKDNSETRSYTTGRYTYSGVRTFYKRHLQADQLPNPPLPLLVCIHGLGGSVAQFHPLLTSLVHISSCLAIDLPGCGRSEFTQQAWDAYTPEALCELLEVIIDEYRQKETDRSVVLIGHSMGTTMCAQLASRNAPHKTDLRKHVVGLVAICPVAGPPTEDKTTLFRRLLWVPGWIFDLWRAYDRWGGPQSASVSRFVGPGADLELRKLQDRFNNQSRTPVWRRMAWGSLQNYENGVAKGGVPGKDVWAGVDVPVYLVGGKEDKLTKPEEVDKIKDYLSGKAPLSPETGSDDGHETIVDAAAPVNTSKNPTDHGPESIDDIRDEDFHRDRKLNEDADNALEDPSTPQESPANVPPQPRHPTKVVRSIIMPAPANHALLFMPATVRILAGLISDFLANHVTGRLSLGWQLQYLSREGKWDVKNLAKWKGVVPVSHPIGPAGSPPVFRAMKTLREADDTHCPAEFVKNWGGIIKDVIDISHDKPVYDPRSMEKGGVRYHKFATVSKIPPKDSEVAHFIALVDKLREQQKARAEEEKWAEVDGQTQVIGVHCHYGFNRTGYFIVCYLVDRCGMSVKDAIETFKEARPNGIRHQHFRDRLYLRYSGLQEEEAVEQQQNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJC3</accession>
    <name>A0AAD8XJC3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_616746</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366265.1">
        <property type="nucleotide sequence ID" value="XM_060507993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJC3"/>
    <dbReference type="GeneID" id="85391892"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="1"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="53912" checksum="2C22514DEECB489B" modified="2024-05-29" version="1">MRYAAPPIGNLRWRAPQDPEPKEGTTDAIDFGPICLGTDVTYPTSGQDEDCLYANVWSPTNTTADAKLPVWLFIQGGGYTSNANPNWNGSQVVDVSGKNVVFVNFNYRVGLWGFLASDRVRKDGELNVGLLDQRLMMKWVQTHISKFGGDPNHVVIHGLSAGAGSVALHLAAYGGRDDKLFKGAMSESVFFPAQPRVPELEYQFNQTLAKVGCTDDKDQMGCLRGKDIKAIQDANIASPFPGRAANPHFYWTPCIDGDILQDYPYRLYDKGSFIKVPVLFGTGSNEGSVFAANVATQDQFVSFMTDNYPKLTKNETDPMLQKYPLLPPLPNHNVWFPSTSQAYGETTFICPANTIMNAYAAANRSGTSWSYRFNVQDNDNTASGLGVPHVFEAPAIFGIDACPTPDSFRTYNKPIVSLMMKYVISFVRDLNPNTYKLAGAPDWGDWGRNQSRFVFELNKNRMENVDDGQRDRCNFWKGIVEVMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJK5</accession>
    <name>A0AAD8XJK5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_614737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366850.1">
        <property type="nucleotide sequence ID" value="XM_060507862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJK5"/>
    <dbReference type="GeneID" id="85391761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="198" mass="22153" checksum="34DA76E9982D04F0" modified="2024-05-29" version="1">MCTETIALCESCGLHRHMHYHRCTAWLWSYRQIKWTFTTPLSSTPKPKNCPFLDGEVKTEIHPGRCPNAACPGHKLRDALDLQAAADGTLDRRTDEQKIDAQRIKMGLKRRPGPVQAFREPLEVGRPHQNRVPVVITDGRPDEGLGVVRGRGKRVEGMGLAEMETEDEGAMAVPSPGPAARVPVRRQRAFHGPMMRPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK94</accession>
    <name>A0AAD8XK94_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_569395</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368965.1">
        <property type="nucleotide sequence ID" value="XM_060504189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK94"/>
    <dbReference type="GeneID" id="85388088"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041767916" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="171"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1728910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="44761" checksum="48A0E4600AA42695" modified="2024-05-29" version="1">MKVAKALPLAVLAHSVTARFVAEEEINRVQLYPAGSEPEKYLIELAPGNTRWVTEEEKWELRRNGNRFFDITDHKEFGANRLHTKTKKSVFPEKCRLQDKVKPLIKDLDKKEIQTNLEKFTSFHTRYFKSDYGRQSSEWLLAKLNTIIKDAGADKHVYAEAFPHTWQQSSIIVTIPGKSNSTVVIGAHQDSINLWLPSILAAPGADDDGSGSMTILEAFRTLLKSKDVVSGKADNTIEFHWYSAEEGGLLGSQAIFSSYEQDGRDIKAMLQQDMTGFVQGTLDAGKPESVGVITDFVDPGLTGFIKKVIVEYCKVPYVETKCGYACSDHASASKAGYPSAFVIESAFEDSDKHIHSTDDNIKYLSFDHMLEHAKMTLGLVYELGFTDFAALEKQGQVSEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKK8</accession>
    <name>A0AAD8XKK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_606787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369162.1">
        <property type="nucleotide sequence ID" value="XM_060507395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKK8"/>
    <dbReference type="GeneID" id="85391294"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="85" mass="9336" checksum="1BFFF5B3951C36D1" modified="2024-05-29" version="1">MGIQPWRNRHAGNYLSIYLFLFCIQHATLFSRSPSVPPIPSVSRGTVWSVSVKVPIRTSRTHGSCGPSSRSPPGWGWSGEETPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKR8</accession>
    <name>A0AAD8XKR8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_569097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369232.1">
        <property type="nucleotide sequence ID" value="XM_060504150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKR8"/>
    <dbReference type="GeneID" id="85388049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF56">
        <property type="entry name" value="GALACTOSE OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="50"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="142"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="2">
        <location>
            <begin position="614"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="715" mass="77413" checksum="FC7DD37686D40B9A" modified="2024-05-29" version="1">MVRSTAYKAIAAASLFSRFSSAAITACPNDEAEWESPIGVKYTVCPGSDYQYGGGSLQYVQNVQTTVECVQICDKDARCNRAVYDKELKVCHVKDTKNEMNWAADDRFDSIRMTNDFVDGTFLATCPFKEEGYRVPKGSADYRVCRGTDYTGNSAKIVQDVTTIQACSELCSITQNCKKAVFDNINNVCHIKAAEPETSLFWVQNKQFDTIHVPENINPAVQGKWGDLIRLPVIPVAAYIVPSYPEPSRLLFFSSWGVDAFGGASGMTQYGDYNFATGEISERAVTNTHHDMFCPAISQLQDGRIVIQGGSDAEAVSIYDPATNNFTRGPDLKVARGYQTSTLLSSGKIFTIGGAYSGKREGKNGEVYDPEANEWTYLPGADVTPILTNDHEGIWREDNHAWLFGWKNNSIFQAGPGKDQHWFGIEGTGSVTKAATRDDDDAMCGTWVMYDAVAGKILSAGGSPDYTDSDATVHAHITTIGEPGTPSEVERVADMAFPRGFANAVVLPDGQVLVTGGQRKSLVFTNTDGILIAELFNPETKEWKQMAPMAVPRNYHSVSILMPDATVFTGGGGLCYVQQILGSTAGCDKTVDHADGEIFEPPYLYNADGTKAARPVVSGVTEEAVKAGATITFSVEGVEAGGKGAKVTLIRTGSVTHSSNTDQRRIPLDDVQVDGQSFSAKLPEDYGILLPGFYFLFVSNAQGTPSIAKTLHVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM90</accession>
    <name>A0AAD8XM90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_783621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370058.1">
        <property type="nucleotide sequence ID" value="XM_060515594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM90"/>
    <dbReference type="GeneID" id="85399492"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="254"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="46716" checksum="8F399A99AF18C60A" modified="2024-05-29" version="1">MGSIPEKTLLDTSIATQANDAKGVAHLANTIGTLGTSFLPNDEQGRLALLKQARSLLQALETPRETMIKHCWAQLLLPSACWTFVIATGIESGLFEYLVQNPGPKTVDHLGKALRFDIDVLSRTLRHLCSTGYLKEVGPDEYEGTNFTRSLSIPIIAGGYPCLVENCWPTFSNFPLYLKKHDWSISPDPREGPMQDVIGKDNNFFKHMMTNHPAGEFQNHMAGYRQGRPSWMDDGFFPVSERLVKGADSSPEAAFLVDIGGSIGHDLDEFCRKHPTAPGRHVLQDLEYVLSQTQKVDRKIEPMSYDFHTEQPVKGARAYYMHSVLHDWTDDVCGSILSRVTEAMKPGYSKLLINENVIPSIGADWQATALDMMMMTLFSSRERTEEQWRKLLEPAGLKIVKIWSAGEGVESLIECELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XND5</accession>
    <name>A0AAD8XND5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_601255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370528.1">
        <property type="nucleotide sequence ID" value="XM_060507087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XND5"/>
    <dbReference type="GeneID" id="85390986"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="15710" checksum="B0ED9C319E688F12" modified="2024-05-29" version="1">MLSSRKNLLQWTAMSIILKLSNPQALTSTTPSISASIAPLVTRLLRLCPILSRHSWVPLVMYALNTYLDRKVIQLPLPIRTMFAVPGRPGICLRIPVTEWLFYTPEPLYLPPFCFLDVCVGRNGITGDTTSSTYASRSAGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNI5</accession>
    <name>A0AAD8XNI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_646887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370599.1">
        <property type="nucleotide sequence ID" value="XM_060510024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNI5"/>
    <dbReference type="GeneID" id="85393923"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05227">
        <property type="entry name" value="AR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000191">
        <property type="entry name" value="Methylglyoxal reductase (NADPH-dependent)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="341" mass="37299" checksum="A6743A5722B21251" modified="2024-05-29" version="1">MAKILLTGGSGFIAAHILEQLLARGHSVVTTVRSEDKAQRIRDAHKDLDASRLHVAIVPDIARPDAFDEVVKTPGLEAVLHTASPFHFKWTDAQKELIDPAVVGTTAILKALKRDAPGVKRVVVTSSFASVIDEAKTEDPNTIFTEEFWNPVTVEDIGRSPATAYRASKKLAEKAAWDFVKDEKPGFDLVTLTPPLVLGPVVHHFADLNSINTSNERVVDLVKGKWKDAVAPTGAAYLWIDVRDLALSHILALEKPEAGGKRLFTTAGWFSNAEIATVVRKNFPELKDRLPVEGTKGGELPPKDKVYGYDNSATEKILGIKWKSLEESITDLVKDIKGFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNW6</accession>
    <name>A0AAD8XNW6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_747140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370874.1">
        <property type="nucleotide sequence ID" value="XM_060513387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNW6"/>
    <dbReference type="GeneID" id="85397285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000043">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="78"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="171" mass="19237" checksum="687FAF723030F9F6" modified="2024-05-29" version="1">MFFLYNMERRVTLHPSYFGRNMHELVTSKLLKDVEGTCAGSYYIISIMDTFDISEGRILPGSGLAEFTVGYRAVVWRPFKGETVDAVVYSVNHQGFFAQAGPLRLFVSAHLIPSEIKWDPNATPPQFTNNEDTIIEPGTHVRVKVIGTRTEVGEMWAIGSIKEDYLGCLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNY8</accession>
    <name>A0AAD8XNY8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_747163</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370901.1">
        <property type="nucleotide sequence ID" value="XM_060513391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNY8"/>
    <dbReference type="GeneID" id="85397289"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000075">
        <property type="entry name" value="Sporulation-specific chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF384">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042007745" description="chitinase" evidence="14">
        <location>
            <begin position="21"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="15">
        <location>
            <begin position="139"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1730846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="523" mass="54784" checksum="C5862CD87D074DA8" modified="2024-05-29" version="1">MVGSSLLLPLLAALASIAGAVPVNERRSVRPTCGKPGTVVSTTQVTIPTSQAATAAPTSPPAVSLPSPITVSSSFVTSSRLASSTSAGGNPVVSSSSVRTSAAASSASAAPSSLSTVRASSTGTASPPATGTGTPASGYRNVLYFTNWGVYGANYQPADIPADKVTHLLYSFADIQTDGTVVSSDPYSDTQRQYSGDDNQAGNAYGCVKQLYALKKQNRQLKLVLSIGGWTWSSKFPAVAASDTARKQFASSAIKLMIDWGFDGLDIDWEYPASDTEATNFVALLKEVRSQLDAYAAANAPGYHFALTIACPAGPSHYKQMNLAGMDPYVDAWHLMAYDYAGSWDTTTGHQANLYQNPSNPTATKFDTQTALAYYLSQGIASNKVVLGLPLYGRSFENTANGVGLPYSGVGTGSIEPGVWHYKVLPKAGAVEVYDSTAGALYSYDSSTKELISYDNPASAGVKAQYLLDNRLGGAVFWEAAGDRKGEGSLVGVLASKMGKLDSNQNLLSYPNSQYANIKSNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP01</accession>
    <name>A0AAD8XP01_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_565804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370861.1">
        <property type="nucleotide sequence ID" value="XM_060503796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP01"/>
    <dbReference type="GeneID" id="85387695"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046921">
        <property type="term" value="F:alpha-(1-&gt;6)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="617" mass="69051" checksum="7F7B469BEC091EA9" modified="2024-05-29" version="1">MPAPLDLSKSKLSISDPRMNLRRSASHTGNTNYEKIPLSATSSRFSFNHLLFSSPPPSPSLPALIPPPRKSPIHPRPSRVFRFTFWFAFGALFLYFATFPFRSIFGVPKLNLPHLGKNDDFEMVGQDDLPDFPTPIVITDKSGKSKWTVSIPPSYDFPLSVKEYGDMCSKCREVAARVRDMRHRSQVTDQNLLSNDAPADPYFIDVTEAQESGLLPDFATSQWPSKGQGRDGDLVGENKDSLVEKPVCERSMTFVLETEDAGIGHSIMQLWTFYGLAQRQGRAFFIDDSRWAYGKYTDIFQPPPIPNCRPPPRHEMIPCPPRARHLVVTSETAKSLWAGSLSKPYADFRAQDEEGLRELFDLAHDGYRALFDLNKDDTQYVINRVKEVKTKSLTGDANPNDGLVVGVHIRHGDCHPLEYKYRGTYIPMEIIANRAQEIIEANYNNTGRDGADDKLAKKQSLIVLASDDPTVYDSEDFKGSVRAQEQIRLASKQETHKPATDKHVMHRFEDESFGWEGGFFAAMFWNLGLSSMSASNAATAKNMQLAPSAETLRLRGYIGRAYMMDLAVLASASDAIVCTVSAMGCRLLAVMMGWESAMEAHNWVNVDGPYGWTGMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPB1</accession>
    <name>A0AAD8XPB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Leukotriene A(4) hydrolase</fullName>
            <shortName evidence="14">LTA-4 hydrolase</shortName>
            <ecNumber evidence="14">3.3.2.10</ecNumber>
            <ecNumber evidence="14">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_599290</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an epoxide + H2O = an ethanediol</text>
            <dbReference type="Rhea" id="RHEA:19037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32955"/>
            <dbReference type="ChEBI" id="CHEBI:140594"/>
            <dbReference type="EC" id="3.3.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13 14">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.10" evidence="14"/>
    <dbReference type="EC" id="3.4.11.-" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371008.1">
        <property type="nucleotide sequence ID" value="XM_060506985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPB1"/>
    <dbReference type="GeneID" id="85390884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000009">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.320:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012777">
        <property type="entry name" value="LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02411">
        <property type="entry name" value="leuko_A4_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="15">
        <location>
            <begin position="506"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="306"/>
            <end position="311"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="603"/>
            <end position="605"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1730953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="648" mass="72343" checksum="ACF3992F9B382169" modified="2024-05-29" version="1">MWRSLLAKGSTPLRTSFTRLTSPQSRAAAFGTTAKMASTTSANRDPNTLSNYGAWLTKHTTANLTIDFEDKSLKGSVTLELESLTHSQSKEIILDSSFLSISGVKVNAATSTWELKDRVEPYGAPLHVFVPQGAAKGEVVKVDVDLATTDKCTALQWLTPAQTSNKKHPYMFSQCQAIHARSLFPCQDTPDVKSTYSFVLASPLPVVASGVLVEGSGKDEKKGDDTVYRFEQKVPIPSYLFALASGDIATAPIGPRSIVATGPDELKESQWELQNDMEKFMEVAEKLVFPYRWGQYNVLVLPPSFPYGGMENPIYTFATPTIISGDKQNVDVIAHELSHSWSGNLVTSCSWEHFWLNEGWTTYLERRIGMAVHGDAERDFSAIIGWKALEDAVALNGADSEFTKLIINHKGIDPDDAFSTVPYEKGFHFLYYLERLVGMDAFDKFIPHYFTKWSRKSLDSFEFKDTFLTFFNGSGDEDIKNKVASIDWDTWFYQPGLPPKPVFDTTLADVCYKLAENWKDESFKPSAEDVASFSGNQKLVLLETIEKFPSPLSADRAKLLGTVYDLVSSRNAELKTAYYKIALAAEDSSAYQGAAELLGHVGRMKFVRPLFRSLNKVDRELALKTFEKNRDFYHPICRGMVEKDLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ71</accession>
    <name>A0AAD8XQ71_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_714918</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371467.1">
        <property type="nucleotide sequence ID" value="XM_060511682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ71"/>
    <dbReference type="GeneID" id="85395580"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001156">
        <property type="entry name" value="Zinc finger protein 407"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050688">
        <property type="entry name" value="Zinc_finger/UBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24403:SF107">
        <property type="entry name" value="ZINC FINGER PROTEIN 521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="125"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="416"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1731412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="46872" checksum="6286E1A0C0544789" modified="2024-05-29" version="1">MAMETSSSFTARRQATQALPPFHLPSTNQDIPSMSRHSHQYPFSFHNQPLQSPSSWQAPAMATPSAPSSSSAASNTQHSPVTASSGLTSPSGVPGEGLSPLSSGVNTTSSQSSYYPGGNGHGSWPTPSSSYQLSSGTPQGLVQTSQYASRGSTYDQQSPMSYSRTSQSPATGEGLPPPPYGQTHQSFQAYPHGGAGSTPVSLPSQGPPTPQGGILGSHGAVSTQPPTPGGLHSHLDSYTQSRPPATPGYYSTSSAPQQSFNSYQQSHTSPTAPSPTTSAGPGRGLAALQHPSAMAPPGSYRYPGYHVPSMGGPIMSNLTSPGHQMSLVTGMGVPGGYGAHHLAPSMYGHTHGGQPNPQAERPFKCDQCPQSFNRNHDLKRHKRIHLAVKPFPCNFCDKSFSRKDALKRHRLVKGCGSKEGDRQDENGRRSSQDHSDDGTPPLKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQL9</accession>
    <name>A0AAD8XQL9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin-like f-box protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_564549</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371641.1">
        <property type="nucleotide sequence ID" value="XM_060503653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQL9"/>
    <dbReference type="GeneID" id="85387552"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042108550" description="Cyclin-like f-box protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="36335" checksum="C02E0534CCE72AA4" modified="2024-05-29" version="1">MLTVRSPVAALAVVLSLLSVVHGAPQPQNRKGNGNRGGNGNGRANRQTAQQQAAAVPQGISQATDGSMILDMTANVNGLDLRFKISGPAEQFTAASGVPGAAAQPGAQGTLGLNVLLHGDGGQSFFDMPNQGVQQNLAGVAVLAPDPNLFWGGGQGLQRTDGVAHSQAVNDLVQKTLPQMMAFNQSNVFFTGVSGGSLMLSGFFMPAHMQNFAGNGVLLNCGGLPPQVDVVDAKAVAGTRIHFQSTLQELSNLQEAIPASVKAYEKIATDAGLSTDQVNAKQTVNNSPNGGHCAFDEQGFVSGIQLVANNYAAIMQGGNGEVQGIGNVLTGVTGNENLQFTGSSRMRRNMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYV0</accession>
    <name>A0AAD9CYV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_716713</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369018.1">
        <property type="nucleotide sequence ID" value="XM_060511873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYV0"/>
    <dbReference type="GeneID" id="85395771"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="41"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="341"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="48871" checksum="4985D70FABAD03F6" modified="2024-05-29" version="1">MSTDAPVAASNGIPEVVTPDAKQEPTEEQEMPFSWLQPHSTFAIVLVGTEQKPFGLQKDFLCAKSKYYREYFKGQNAASEAIENVVKLPQYTPEVFGLAQLFLFTGEVSEDAESFTSYESLVGVWKLGHELGIDGLCDTSLDAMKECRRLTQNIPATPLLVQVWKDTPEGSTIRKLLLSWAAEYMRSSDKKAEFAKSLPQEVLSELVVTMSSLENLPTPPAAADTASAEPTPRKSVHYLEEDSEEEQEHMSKKNRRASAPLPASQNRDKAFSRAPPPPVRKAAAVAAAASAPRQKPVIQKRRSIVTGPSGEITTSQKVEFCSDLLDRMLSGPGFWTRLVGPFKEPVDPAEDGVPDYFEKVKKPMDLNTVKLKMSQHQYQTEDEFAADVRQIFENCYTYWKKGDPMWAACEKFQRTFEDKYAQMHKNISKMLREPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ42</accession>
    <name>A0AAD9CZ42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_607664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369034.1">
        <property type="nucleotide sequence ID" value="XM_060507442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ42"/>
    <dbReference type="GeneID" id="85391341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF9">
        <property type="entry name" value="L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="29914" checksum="E68396B91B8A3D15" modified="2024-05-29" version="1">MSSKISFKPKVSITHIGTATAILDIDGVRFLTDPFFSPAGTTWDVGVTILQNTEDPALKLDQLPPIDAVLLSHEDHPDNLDELGRRLLDGRHVFTTVDGAKNLAPRPAVVGMEPWTTVERRIGGKVFRITATPCQHLPGGECIGFLLSSDDFGIGPNKLPNAIYFTGDTVYMDELTTITDKFHVPIAMMNLGSAHVQFPDRDAPLQITMDGKQAARLFREIKADHLVPMHYDKSWGHFTQFEEGLAKDFRDEGVDDKVRWLKPGVAVEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2K1</accession>
    <name>A0AAD9D2K1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TAFII55 protein conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_646703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370865.1">
        <property type="nucleotide sequence ID" value="XM_060509997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2K1"/>
    <dbReference type="GeneID" id="85393896"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08047">
        <property type="entry name" value="TAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037817">
        <property type="entry name" value="TAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006751">
        <property type="entry name" value="TAFII55_prot_cons_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228:SF0">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04658">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01370">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII55 protein conserved region" evidence="7">
        <location>
            <begin position="145"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="494" mass="54676" checksum="573005D0C1C0A2D9" modified="2024-05-29" version="1">MPDTSAPPPPRPKLKLSVNSRQTSFSEQNGATPTASTPSGMKIKLKSSQPPTPAGPAAPTPIKTKAGRQSKPTSKLIESKKREQDEDDDGANQPSSKKIKLLKTPNVSTPRSGHIVVKSKGKPPVHPPGDGYDSEASDQEKDPTIEEHFILRMMPGEHCEYVRKCVEEGKVGLPRKDGGADIMMKFFDDESRRAVVVVKNQPYAAVMVELPTITEGMKSWDRKTLMKSADICHMLLVFQPVKSDEEAKKAPLPAMIQPGFKWPHGLTPPMHDATNQRFAKIISRSEIELKENEVKKLLQADAAAMSSKYEFIDDRKMQSGDEYSDDEQDADGEADDSGYFPSEGYANGELFDDDDHDLEAELEAAFEEELNQATTEVGTPATQVEGATPMTMNAGTPAANTRDGDESVASEEDEDDDDDDDDDDDDEDKPPQDEIKAVREDIVNLKAEIAKKEQEKALQQNKILRKRVEDRLKQLRAELALKQTSINEEEEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D343</accession>
    <name>A0AAD9D343_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_746301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371958.1">
        <property type="nucleotide sequence ID" value="XM_060513246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D343"/>
    <dbReference type="GeneID" id="85397144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF28">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="278"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="499"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="596" mass="64580" checksum="48314ABE36C7118B" modified="2024-05-29" version="1">MASTTTSLPRIPLFEAISQHDPESTAVIHSLSGRRFKYGELLGDVRRTRNKLLDSAGKSDLNGERIAFLVENSYDYVVTLLAAFAARSIAVPLSPAFPAAELQYILNQSEASLLVSSAKFAAKTREVLATELLSSPTQVELQKHLGGSVHEQVELDNSDADGAGMMLYTSGTTNRPKGVLLPQSVLTAQSKSLIEAWNYTPADHLLHVLPLHHIHGTVNAVLTPLLSGSTIEFMFPFNADAVWKRLAAPYITSNGTNGVNGTNGTNGVNGTNGTNGTHKNIAKEKITFFTVVPTVYSRLLATHKLLPLDPAEPTREAVSPRNMRLAISGSAALPTPIKEAWKTLSKGNVLLERYGMTEVGMALSCGLDFADRVDGSVGWPLPGVEARLVDMDTGLVIPPGEDVDPKTGRERSGEIQLRGPTIFKEYWRNPEATAKEFVEGEDGKGKWFKTGDVAVRRPVPNAGLNAAQASWAKGDMYFIQGRKSADIIKTGGEKVSALEVERELLSLPEVAEAAVVSVPSGKWGSKVGAVVILNTDVVPHWSPMAMRRALRDRLVNYKIPQVLKVVNHIPRNAMGKINKKQLVQAVFEDQFSGDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3A5</accession>
    <name>A0AAD9D3A5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED17</name>
        <name evidence="10" type="ORF">BDZ83DRAFT_564744</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3A5"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="572"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="73287" checksum="E2167E0C8CD91C6B" modified="2024-05-29" version="1">MASGSSMPFSSLHPVPTGDRKPKSLGEFIARVQAERGFRNVTEESLKEEVENKKNGVGEVKEEDTTMAEGDDEDEEPLDAGAARMEVLRNIDTAHNAALMTLDFISLLLSKESPAQAGVTLSQQLRDWTGIGTLGIAKREDNEEQKQRDAEKAKDNRDVSLGWALLDIEKTKESADKAATHLSKEVEREAKYWDEVLSVHQAGWSMCRLPAERHTLGVRFGFSEASPEFRNSSLAPLRRGDDGSALLQHGRVGSGCQRLAITVSRSGEPSGRLAVGASVPDSALLPDRVLEARNTIFAQELWHELHREAHSLASYGVRADNNSINFHPSSGPSLTLELETLEDSAATVGASPDNVLAEATHLGLHILLSHAHRLNELQRLRPTPPHQRRNQTQNQYHLLRPIIAKILYDRSVEQVTSFAGDLTRVLRQAGVDAASFTLNTPPFPTAELKNTSGGASNRPNASQALTNMLTSPADFQIELTLTPTSRLQIRGRTFLLPLTTTQFQLQLLPNVGAAAAAGSEPSNGEQPPAPPPNTLQSSYPPSRDPYPDIASVQLYITNAAAHALTDHAMSLIPPPQQPSDPSTPPSEPAPAEWIKSVRGTAIRDIDTETREIRFDILNSGPENRLTLQIGAAWRAGDKPLLQRWSWAAGGDPSSSPSQPHVSDIVAAVVQSREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3R2</accession>
    <name>A0AAD9D3R2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_11142</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372020.1">
        <property type="nucleotide sequence ID" value="XM_060501091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3R2"/>
    <dbReference type="GeneID" id="85384990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="21430" checksum="6144F705C969D711" modified="2024-05-29" version="1">MPSQESRSSEDISDTISQEPMQCHEKRNDDDANQDRPETARNVSEKDKDNTEASSAESSAQNPPSSSEEWLIKRFWGKQVSVVVEFETCRDHLAIERTFLGYLRTSLATAVLGTMVAQLFALQALDTGFGYTAVGKPLATLCYSFSICIVLLGAFRAWRLQHAMFAGKALAGGFELTTLALGFLIVCCSDTITQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3U4</accession>
    <name>A0AAD9D3U4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371886.1">
        <property type="nucleotide sequence ID" value="XM_060513236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3U4"/>
    <dbReference type="GeneID" id="85397134"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046591">
        <property type="entry name" value="DUF6649"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20354">
        <property type="entry name" value="DUF6649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="250" mass="28258" checksum="6432B71A341C120B" modified="2024-05-29" version="1">MLLHGTQSPSHALEADQHQHQHQHPQARQLRRKRKAESQDNERLSKRLSLLNLEKNGQKLYVPVEEPTPSSSIPIPADSSSASTSPPTTRRRRRDRKPSVDEEVMQLDDSKHKVYIYNIDDELSSSESEPDEGKLVFLPDIEKHLRQTRIPPSIFANDEGQLAGMQVVLYNEPASLTVPREQDSVRKAIVESRARMRERQRLEREGRGAPVQMPPPFVSQQPVDAIIPGPLTPTGMSAPVDYDPDAMDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5L3</accession>
    <name>A0AAD8U5L3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_191620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357841.1">
        <property type="nucleotide sequence ID" value="XM_060501599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5L3"/>
    <dbReference type="GeneID" id="85385498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="24654" checksum="1269A8AEBEED9CF1" modified="2024-05-29" version="1">MTSSQTFFRPSRYRIAQVRIPGDTTATMKWTIIYWLLPLACVAQIPVDPLPFTPLKPNPTQKVFPTTTWCATVTPTEIPGVKPNATLSCTTYAPEPTVFARFNRIPRARGQARCWYDSYVDRIEIEKRTLNTQAEILKGVYECQDRCQQPLSNGKECKYAVYVKAGPRSKDLCLLDNLVYDPYAVNYRGPFDSWLCIGSEKMLPEIEDAPDTNEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6A9</accession>
    <name>A0AAD8U6A9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000309">
        <property type="protein sequence ID" value="KAK1702483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357138.1">
        <property type="nucleotide sequence ID" value="XM_060509835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6A9"/>
    <dbReference type="GeneID" id="85393734"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="580" mass="64575" checksum="4219DF41F0AA375D" modified="2024-05-29" version="1">MNDHEIFRRLATYPFTSATLKMLQCALQVIQKRYPLASLQDGGDAILEYPSQEAFEQTEVPLHVTGEWISLMKIVGDSIDAPEQRVPLPLRLFARGEQADVDMIAEYLRLLRPAYPSFHFSDPVIFTSDNTETAARLYGTFDATTLIPCSYDGAWFAAVAYADCVQLYGAQVESSSKLEQQAQTLFPGRTICFSEPLVTTPVKDPGALMLLSLRMLAGGGVPTMCADAAFLQNLRARICVELLAQNLDVRDSDVSERLQQVQLENSTFFDEAFIREDNSPSPVGSTFTADMGSNIGPSTFGASPSPSRLFSPVGEGPPSAGRGSSETTSASPKDLYRPSLFSRAVGPSPKWHVFGTRIHGVSHSVSPPMPPPMPEECRVILGMLSEAVAFYRSSRLSGSTELAVMWSAIKSGSKSEFYRRYIGLLFYEEMARLSSDQEVALRLKTSITKRELGEMRRHQSDFQIWHDICDLRRDWGPGRFVLLCALPESFQVGRGSRTEKQVQLRRVCKRLQDDRDPLSGYLDVAKELCAALVQVNLPCERLMIDDYHLKAYSEMSEPEFAAYMSLSPRPVIPISRWGTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U701</accession>
    <name>A0AAD8U701_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_724151</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358651.1">
        <property type="nucleotide sequence ID" value="XM_060512627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U701"/>
    <dbReference type="GeneID" id="85396525"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF41">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990814" description="Mannan endo-1,6-alpha-mannosidase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1709740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="458" mass="49126" checksum="9C5BCE6E8BE8D0BE" modified="2024-05-29" version="1">MRPTLGLPALAVGLKLASVSAIDVTWTDEDSIKSAAGTVAYGLVKYYTGNNTGDTPGNLPDPYYWWEAGAMFGTLIDYWWLTGDDSYNTITTQAMLHQVGDDNDYMPQNQTLTEGNDDQGFWAMAAMSAAEHKYPNPPEGSPQWLALVQAVFNEYVSRWDTENCNGGVRWQIFTWNAGFDYKNSISNGCFFNVAARLARYTGNTTYSDWAEKVWTWQTDVGLLTSDHEVLDGVHFEGKCPSSTDSTKWSYNAGIFLYGAAVMYNITGSDTWKTRLDGMLTDVQTAFVQNDIIYEAYCEPTAQCSQDAQSFKGYLARWLAATSQVAAHTADTITALLLSSGKKAAITCSGSPASGFKGHAGTACGFSWLNETFDGIVGVGPQMTSLQMIMYNLVGSAEAPVTATTGGNSTGDVNGGKTDDGSGSSNSLKAITTADKAGAAILTIMVSASVVAGSAFLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7P9</accession>
    <name>A0AAD8U7P9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000244">
        <property type="protein sequence ID" value="KAK1705315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357583.1">
        <property type="nucleotide sequence ID" value="XM_060515060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7P9"/>
    <dbReference type="GeneID" id="85398958"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1705315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="36796" checksum="8A78E4411FE62241" modified="2024-05-29" version="1">MASVNLENVFDAGAKVSLNVPLVIPEEDHIVWPLVMAGNLGQLRDLLSRDRNLMHVRNQWGQSIMHVAAKIHQPAVFNFLKDEGMDENLPDENQKSAAITVLTRRGSQEYNLPVDTDDLADRLGWTNLHKVAALGARNDQEITETLLRESEYSDIDTEDVLGRTPLHWLAENGKSGAIRLITQDPWSANVQARDLCGFTALHCACWADDFDSIVALLDAGIDVNALDKHMRTPMMHMSSPEILKYLLRKGADVQISDDEAANIMHHACVSDQEDLVEILLREYGHSLLTRNHTGDTPLGQAIANNSLEVLKIMAPYLRGFPVSLPLFNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8K6</accession>
    <name>A0AAD8U8K6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450 2D18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_758920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000287">
        <property type="protein sequence ID" value="KAK1703238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357255.1">
        <property type="nucleotide sequence ID" value="XM_060515110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8K6"/>
    <dbReference type="GeneID" id="85399008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1703238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="60964" checksum="DA409AD681360559" modified="2024-05-29" version="1">MTVTTIDLPVLGSYPSLIWIIPAAFLAFKILTFGSREKYLPPGPPTLPILGNAHLIPSRGMYTKLKEWADQYGSIYSLKVGQSTMVVLNDRHAVHELLTSKGAYYNDRPVDQQYDLAMRQENTSLMHDGPVWRAERKIAATYFSPKNLDGALRGVQESEISFLMYDLLKKPDEFMKSVKRTTASIATITIFGQRAPSWESFWAYAVYIAMDGVSTILEPGSYLPVDQFPILKWIPDRLAKSRQRGKELYHTITNIWTKAREDVELRRSQGTKRESLIDKLLDEEIKCDVPLSYTAFNNFLGGLQMAAADTTATATLTNILLLAKHPDVQEKARVELDRVCGTERFPNWSDFKSLPYINCIVKEGLRVKPVVPTGVPHASKQDRWYGDMFIPAGSSIFIPAYALNHNSDLSPDPFTYDPDRYIPVADKLAPELAASPKYEERDHYSYGAGRRMCVGLHLAERSQWRMVAQILWAFKIEPAIGSDGEEVELDSSPEGYIEGLLHTPKKYKVKFVPRSEKHVEVIRQNFDEAVEFLKQWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8P8</accession>
    <name>A0AAD8U8P8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_772806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000285">
        <property type="protein sequence ID" value="KAK1703344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357271.1">
        <property type="nucleotide sequence ID" value="XM_060515396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8P8"/>
    <dbReference type="GeneID" id="85399294"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40616:SF1">
        <property type="entry name" value="LINALOOL DEHYDRATASE_ISOMERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042078130" evidence="1">
        <location>
            <begin position="26"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="60697" checksum="3F6E4A8C3725BD7B" modified="2024-05-29" version="1">MAVSVKRLVAVGFLSALGLKQQATAVELSGFTKDLFTESMDFLDKIYDPAAGYLYFFYYPLAAGKHETRSSVWYATGLLQRNIGDDVAQATKIIKNVIRDQKKILEEQWYGDYTVYPEEPTVGTAAYPKSIYNTWDPNWRGFIGTTLIVIYEEFRHLLSSDVQDLILESMYNNTIGDSYRVGGVDDDNLYPSYSNPAIMRAIATGWTGHTLNNSNMTAAGELYAQEILDLFDRNSTLSEFNSPTYAGVSIYSLTLWAKYMPSDSSLMGQHGARMIKAIWESIGSMYNANLRNVAGPWDRTYGFDMNQYVAIINIYIWSLVGKDRAPGISQTWSMAHADDFEYAPLISVLAPFHDALVPSDVVEKLTVFPGEHMYETAAFSPPHDSVPRNITTWLSANLTIGAESYDEDTLGGPREDPSQWSTAVVQWARNDGSVGYAVLHGTEEALNVDVSPGHLSLSYPRGNSTSIFTFLVSSNPLSGKRDISGFNDLEGIQVSVSGSVNPQPEIGFCGLVGGTCSIIHGFEFWNITFVMLGNSSTVPSIELDIKSVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9W2</accession>
    <name>A0AAD8U9W2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pectate lyase Pel-34K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_771136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000244">
        <property type="protein sequence ID" value="KAK1705321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357589.1">
        <property type="nucleotide sequence ID" value="XM_060515359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9W2"/>
    <dbReference type="GeneID" id="85399257"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041948447" evidence="5">
        <location>
            <begin position="19"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="6">
        <location>
            <begin position="46"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1705321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="33801" checksum="2F86187BCBB173FA" modified="2024-05-29" version="1">MKISSIVVLIQGIVAAQGAVTERQSSGCLAAATGFASLNGGTTGGAGGTEVTVTTQADLEKYASASGKYVIKISGRITISPLGKEIKIASDKTVIGLGISGELYQGGLGLNGARNIIIRNLKIGHTNLNDGVENDRDGVQADTVSNIWIDHCLFEDGGDGLVDLRKDTTYFTVSNNIFRNHDKTFGIGWTENVTARGTINHNWFDNTNQRNPSADNLAQAHLYNNYLYSVTSYGHYARGSTNARVENVFFENTKNPLTKDSGAVLNATGNTYKSCTGTMAANSGTSFDPKSLYSYTLTATADVPAYVKANAGPRASVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA30</accession>
    <name>A0AAD8UA30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_110219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359162.1">
        <property type="nucleotide sequence ID" value="XM_060501084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA30"/>
    <dbReference type="GeneID" id="85384983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041915894" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10497" checksum="20991409FDC8DCEC" modified="2024-05-29" version="1">MPFLFAMLATVVVIVRPCLAPWSPTSEAGCVIHPSDVEIGNGPLANVYQITTQARRHRERMKTAMCPNLFGWQKSKCKDKTLREEREALGLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA74</accession>
    <name>A0AAD8UA74_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_593152</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000207">
        <property type="protein sequence ID" value="KAK1707558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358095.1">
        <property type="nucleotide sequence ID" value="XM_060506600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA74"/>
    <dbReference type="GeneID" id="85390499"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041997290" evidence="2">
        <location>
            <begin position="18"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="168"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1707558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="39432" checksum="84733AA12F59748B" modified="2024-05-29" version="1">MQVKNILPLALASTVLAQSQQSLTAALASQNSSLSSLTALLGTQPALVEALSQAQNITILAPSNAALEAFLASPGAQGAATNPGLVAAILQYHVLNGTYYASQFTEEPQFIPTLLSNETYTNITGGQRVQAQTVDGNVTFYSALRENSTVTAGNVNFTAGTIHIIDKVLSVPQPIPDTLRAANLTAALGAVQAANVGPTLAAAKDLTIFIPNNEAFRSIGNLTANLTAALPSILQYHVVAGAVLYSPDITNTSLTTLNGGNVTVRVINETVYVNEAEVLIPNVLVANGVVHVIDNVLNPNNTSVEPDTTASTRAPAYTGAGTATDGSNPFTSGITGPTSTAPLATETGANNGGGVRTTSSSTQAGPMRTAAVGAAALFGGMAAYMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAY7</accession>
    <name>A0AAD8UAY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_725004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000259">
        <property type="protein sequence ID" value="KAK1704670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357471.1">
        <property type="nucleotide sequence ID" value="XM_060512711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAY7"/>
    <dbReference type="GeneID" id="85396609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF7">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="185" mass="20588" checksum="5403352912235565" modified="2024-05-29" version="1">MGLYLQATTSTAEDLSIERIREFEASLRPVYAPLTVADADGQSPSEVSDCSTSTTEAEAVHAFTLVRIFQHTALLYLYRAICGLPTRHPLVQQHVKSCLACIFEIPREANNLNCIVFPLFIAGAHVSLAEEQKAVLDMADVIYDDMRFASIDAVKSFFKTIWPSKSGEKTWLEIFSHLSPHVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCB4</accession>
    <name>A0AAD8UCB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lactase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_585569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361381.1">
        <property type="nucleotide sequence ID" value="XM_060505856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCB4"/>
    <dbReference type="GeneID" id="85389755"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000018">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF1">
        <property type="entry name" value="LACTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="6">
        <location>
            <begin position="750"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1041" mass="117074" checksum="53156BA1137947F0" modified="2024-05-29" version="1">MASPSLSLQAKEGVHDYENPSVFRRNTLPPRAYFIPETSILLNGVWDFHMAGTPEEAPLPEDKEDEWGTINVPGHWQLQGHGFPWYTNTQFPIPVNPPYVPSENPTGTYRRTFHVPSTWDEKSQLRLRFDGVDSGYHIWVNGTLIGFAQGSRNASEFDVTSILKRDGPNELFVRVYQWSDATYIEDQDQWWLSGIFRDVTLLAVPEQTRIEDWFLRTDLDEKYEDATFLATVDVKTVEKGTVKLTLSELGKNGGAVIATQEVEVTADNTKVDISIPVTNPKKWTAETPYLYRVDITLGSHAVYQNIGFRKVELKNGLISVNGTPIRIRGVNRHEHHNKFGRAVPIEYAKRDLLIMKNHNINSLRCSHYPPDPRVFQLADELGLWVMDEADLECHGFYDAVARPQDVDEASDYEARKAITFPLAGKYTSENPEWREAYLDRMVQLVQRDKNHTSIIMWSLGNEAFYGENHKAMYEYAKNFDSGRPVHYEGDVKAETADMYSYMYPPIDRLTKLVETEGVKEDGSFEKPVVLCEYGHAMGNGPGGLDDYIEVFEKFPRLQGGYIWEWANHGIWKEDADGKGYYAYGGDFGERPHDGTFVMDGLLHSTHDPTPGLIELKKAYQPLHLSVEGNQLVIKNKYDFVGVDHLSSTYKVEELGEISALIAAGNLEIPKIAAGETVKVDLPSSLANIKSDKEVYITVTFGLKDSTNWAEPSHEIAWIQHKLSGVAAAPKLLNSTLTSKLQVQKARAKTTVSGSDFAITFDTARGYITSWTAAGVPLLEKDEATGAAIIPNFWRAPTDNDNPNDAPYWVRFGVDAFDSFLRSFKINESADKVEVITTTYLSPRVLDWGWETTTTYTIDATGRLTVAVDLKPRGIKPTHIPRVGLNLRLPKSLNNVKYLALGPGESYPDKKSSQHLGVFSATVPELHQHYEVPQEGGNHLETRYVKLTEDHGRGIRATPADVAVWSEEEWRQFSFQVSRYTSETVHKAAHPCDLVEEDATLLRLDARVAGVGTAACGPNVREDLKVHVGEFKFGFVLERVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD40</accession>
    <name>A0AAD8UD40_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_755790</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFB7 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360812.1">
        <property type="nucleotide sequence ID" value="XM_060514666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD40"/>
    <dbReference type="GeneID" id="85398564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008698">
        <property type="entry name" value="NDUB7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20900">
        <property type="entry name" value="NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05676">
        <property type="entry name" value="NDUF_B7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1717325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9824" checksum="0F06D3BC9E6E6C8E" modified="2024-05-29" version="1">MAGDSAPREATREEMREAKLPLPYRDSCAGLLIPLNRCRVDTWYLPWKCNDERHSYEKCQYDEFKKRVAKMNELRAEKGTRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDE3</accession>
    <name>A0AAD8UDE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_656303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359729.1">
        <property type="nucleotide sequence ID" value="XM_060510867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDE3"/>
    <dbReference type="GeneID" id="85394766"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="23889" checksum="07380965DE27D70A" modified="2024-05-29" version="1">MSTYAAKGQWDYPPQVELCWLYAAANDNVHAEALLACQGFGCTVATEGIPILWGIDVSMANSNDTTTTFAVMSSTPDGRRFLNLAAALTAFLSIEDGAKALALLMAASVSNPQQRVPSSEHLTMILEALVRYLPQERNKNLASRYSAAARRHSDPEAVGLASWIQDWIARNHDNTHDFIEDDIFALRRQIKAFLDWCQRPERKLLNDSECKGGSGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDM0</accession>
    <name>A0AAD8UDM0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_636922</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359880.1">
        <property type="nucleotide sequence ID" value="XM_060509282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDM0"/>
    <dbReference type="GeneID" id="85393181"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="700" mass="79356" checksum="98809C98A010F890" modified="2024-05-29" version="1">MMETHGKKPERLHRAAFSSRMKACSSCQKQKVRCLPSGRDGACQHCRKKNIECVFKRPAREIETGSNDASPNRSEMVDDLRMLHTAINSLLRQGSQPLLGPLKTSLTGRLNVESLPLDDTGTFIEDEDQEMEEQSGSFCAQSEELVEPLSQAPISSLHEITRLRSANANGAVSSAPLAVQPPAQEPQDLITEGNLQRVDAERLVKRFLERTDYYLYGITSRFEDLDSVRRASPLLFVAICTVSALHEHRGEQIYRVCSARLRKLVSDFMFKKHVNLYDFQGLCIASFWLSDLSWSVSGLAIRRAIEFQLDKSYEIVIGTSQLDDRFSNSLGLKDREDVLSCLRVWYLFYICDHHLSILYGRPSSFGNPSSVEGWRKYLRSVPSSSTDVRLSSQLELLSILEKVTYMFGSNDDSRISGRFRKELDEFDLEVDRWHNLWAARYRTQRDIERQIGAFPRKNLRLHYHFAKLFIGSHVFRGLSSNPVDDPIPIEFHALALGTVESARSTIQLISNDPDLKAGLVGLPHYNHTMIAYACTFLLKVATKYHRHLDIDQNDVFDHVSKAAEICQSIQCTRYHLVSWMGAGLAKFVENCRKLAGRQSETFADGRERETTVSPTLPTRKVRAMSRTMPSNDAWDSARRVAEAFPTSLQGFMDGNYNFPDDAVGMDSMETLDLDILDGSDPAWDSFLPSFNFEHMGFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDN6</accession>
    <name>A0AAD8UDN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U1 snRNP splicing complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362292.1">
        <property type="nucleotide sequence ID" value="XM_060512389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDN6"/>
    <dbReference type="GeneID" id="85396287"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30635" checksum="B705ABD6A776AA82" modified="2024-05-29" version="1">MAAEQRKLLEQLMGGSASTRAASLSMTDPKVCRSFLVGTCPHDLFTNTKQDLGPCPKQHSEALKAEYEGLSDKEKQKYGFEYDYMRDLQKYIDDCNRRIDSAQRRLEKTPDEIRQTNALLKSIAELSSTIHNGTLEVEILGEMAEVSRAIDEFYRVRQAQQTKSDREKELKALSDTSGPSGHQKLQVCDVCGAYLSRLDNDRRLADHFYGKMHLGYAQMRKTFDAFPKEMRHRQRAPMDDDNMGPGGPRGPRSGGGYRGRGGRGYRGGGGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDR7</accession>
    <name>A0AAD8UDR7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_630391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362086.1">
        <property type="nucleotide sequence ID" value="XM_060508823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDR7"/>
    <dbReference type="GeneID" id="85392722"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="62" mass="6878" checksum="4578171D5419CFDD" modified="2024-05-29" version="1">MVVLLTKYQAIDVSAIGRRGNIDGHCEPKLEDVGFARKDERGNVGTGFPVLENCSVMEWLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDY9</accession>
    <name>A0AAD8UDY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_588590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360060.1">
        <property type="nucleotide sequence ID" value="XM_060506150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDY9"/>
    <dbReference type="GeneID" id="85390049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF39">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="49"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1714917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="61490" checksum="F7A529F53D9B52C5" modified="2024-05-29" version="1">MASGTEEKTVGLSRADSTNSNKLGTVMSGTNAAVAQQYGETQRGLSPRHVQLMAIGGSIGTGLWVGIGGVLSKAGPLSLVLGYTFWGLLFIWPLNLSVAEMCAYLPIRGTIFELASRFVDPALGFAMGWTYFFAGLMLVCTEYSAVATVIQYWNADINPAAWIAVAMVSCVAVNLVAVKYYGESEFIMASTKVILLIGLCLITLITMSGGNPMNDAYGFRNWGDGNYIHAYFTDGSTGRFLGFWKVVIYAAFTIAGPDMIALAAGEIQNPRRTIPRVAKLIFYRLVGFYVVGVLCVGIICSSRDPGLLGAIESGEPGAGASPWVVGIKNLHIKALPDIINAFILLSGWSCGNAYLYSTSRTLYGLARDGQAPKFLLKCTKAGVPIYSVLVVTVISCITFLVSSNGAVDVFFWFVDLTTTALIMTYTFMLITYMGFYRARMAQNFPPETLPYLSPWTPYFPGLALLLGILALIFVGFDNFYPFSVRGFITSYFGLIFGVVTFLIWKVLKRTRFVHPKEADLISGKAEVDAECRHWEEGGIEEVERARLAEMSFVRRTWEKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE96</accession>
    <name>A0AAD8UE96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferric-chelate reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.16.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_721298</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH</text>
            <dbReference type="Rhea" id="RHEA:28795"/>
            <dbReference type="Rhea" id="RHEA-COMP:11342"/>
            <dbReference type="Rhea" id="RHEA-COMP:11344"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.16.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362637.1">
        <property type="nucleotide sequence ID" value="XM_060512376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE96"/>
    <dbReference type="GeneID" id="85396274"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF28">
        <property type="entry name" value="FRP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="250"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="445"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1722582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="61990" checksum="CA7A0E3473980AB8" modified="2024-05-29" version="1">MIEPRAAKQPKPPNARQLLNEWNVKVYAGVVAGVIAALIIYHWAQWIKRRTSKSPRTGSSSPFAKASRKIRSLLVRKAPGFPTGGHALLTIAFVGVNVVMSFHHVDKVKMSNFAARFGWMSTANMALCVFFGLKNTPLGVLTGHSYERLNFFHRLAGYVAVLQMLLHAIFYMVYYGMQDRWSTLLEVQNWEGIGAGSAMLLLLMGLARNLGYEWFYVSHLAGFLLAVIFTGLHRPYWIWKIPVAMIFIAAIWGLDRLIRGSRMLYNLVNNSATIYRLPDNGVRLVIKKPLSGATPGSHCFVWIPGVRPLQTHPFTIVSNTPHGGLELVLSSYDGFTKALHDLANTEAGTTVWASVDGPYGAFPNPKNYDKVVLIAGGSGATFTFGLATSLLQHLESESHKRVDFIWAVRKRENLEWFTDHLQSLSQHGAGVNVLLHVTREGSTASLSESSENVSSPTSLKSPNEKVKALFPESGTEQNKEALPSTAAVPRGDRSAGLEGLCDIKFDKLRAGEAITQTLQSAAPGQRVLIAACGPQSLTEIVQNAAAHCIATGEISIEVHCENFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEA9</accession>
    <name>A0AAD8UEA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_588309</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360164.1">
        <property type="nucleotide sequence ID" value="XM_060506124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEA9"/>
    <dbReference type="GeneID" id="85390023"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="60"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1715021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="498" mass="54259" checksum="17432A2C964A8270" modified="2024-05-29" version="1">MIRPDTPEPQAQILASKPPIQNHDPEAVHAVDGEALIVDWDGQGDPEHPLNWSNGKKGLNIAILSLLSVVTPLGSSMFAPGIPLIMEEFHDESSVTATFLLSIYVLGFALGPLLVAPISELYGRRYLYIFGNILFTGFTIGTALSNSIGMLLTFRLFMGLSGVVPLTIGSGSIADMMPPEKRGRAVSIWALGPLLGACVGPVAGGYLIRATGWRWVFWLISILAGIFIPVSILVLRETYPPAILEYKAGRLRKKTGNQEIRSRLEQKTRMSEKLRLAAMRPIKLLVATPVVTLNALYIAISYGILYLLVATFTFVYTEHYGFDESSSGLSFLPAGIGMVVGVIGFGQLTDLIVKRTKARGLEYKPEDRLKPIMTVPCALALPFGLSLYGWTVQNEVHWIVPMLGVMIICIGLMGTMTCIQNYLIDAYPQYAASVTAALIILRSLLGALLPLSGLEMYDALGLGWGNSLLGFIALSLVPILVSFFVFGERIRGRFNPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEJ0</accession>
    <name>A0AAD8UEJ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sterol 24-C-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Delta(24)-sterol C-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_635872</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of methyl groups from S-adenosyl-methionine to the C-24 of sterols.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Steroid metabolism; ergosterol biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10 11">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360269.1">
        <property type="nucleotide sequence ID" value="XM_060509212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEJ0"/>
    <dbReference type="GeneID" id="85393111"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003838">
        <property type="term" value="F:sterol 24-C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF1">
        <property type="entry name" value="HYPOTHETICAL LOC100005854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="12">
        <location>
            <begin position="82"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1715470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="43111" checksum="836400E31EA68F37" modified="2024-05-29" version="1">MVGTIPEEGQMLLAKDTTFEKILHKGTFKDVGMSAMLKKDYEAQKAATDEYFSHWDNKSAQKETKEDREARTADYASLTRQYYNLATDFYEYGFGQSFHFSRPSAGESFKQSIARHEHYLAHAIGIKKDMKVLDVGCGVGGPAREIAKFTGAYITGLNINEYQVERATKYAVQSKLDKQVQFVQGDFMKIPFEDNTFDAVYAIEATVHAPSLQDVYSEIFRVLKPGGVFGVYEWVMTEKYDNEDLRLRKIRIDIEQGDGIANMVKASEAVRAFQAAGFEMIQNEDMAERPDPSPWYWPLDAGSWRHAQTVGDLLYTFRMTGLGRAFTHGFLGLMETLRLAPPGMMKMSDSLCVAADALVLGGKEKIFTPMYLMVGRKPAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFD7</accession>
    <name>A0AAD8UFD7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl hydrolase family 43 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360516.1">
        <property type="nucleotide sequence ID" value="XM_060506052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFD7"/>
    <dbReference type="GeneID" id="85389951"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1124"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1249"/>
            <end position="1261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1267" mass="137326" checksum="36E2572F37B0A91E" modified="2024-05-29" version="1">MNRFRTKKRAKDDAASSTPRASHESESPAPFRLFGKGKKSQEEEPKKELDLENALPHSDDFRTSLLMTGLSARFSMLREQDDPNTKIGKASDDSVLFPKRQSRMLDFGFGPGTNGLSDIAEVESIRKEVPFNRMDSYHSADGNSISGSVMDRAKPGEGNNLFGGRQKVYKLGSGAVSTKNLDGGGMSGRVLYDDDVAKSAFQKWRQTEKSKQSFDDEQDQKPSSIDLPRAESPPPLGYDRKRETNSTTSSTPSLGRNSTAATSVMSQPTSAAKDWQSNPTAPSSATGTPNLDRSVTRARRLYETGLNHDLQEQQSSALSRMDTLSRQRTLGSRTPDLQNGPSPTSSLFSDRFGNERRILAKGSAPNLRSASPPTMGSPIVPMDLGINVPTNSEPKSSFGGAPPLSPPISEGEESSVLPSDRGKATAMGLFQKPLHSYDESRYAQRQLQLQQGRETPTNRFRTESNASQTTGRSRSSSSAQRLPVEKPEPIIRTEPTVKEEEAGLSFYDDSLSPQDDATNPAAVFHGAARRPADRDHPALRDFAVPTPLSLSTGASVEPSPVSDLPFTAVSAESTSSPQDSPTLPSSAGLSGMVRQHLRTDSATSSIYGSAPQTSNFASRFPLDPYDPKSMADMGVMANPWEVQSPDWRNSTFNEKEQPSNDQKESAIPELTSQPRQTLPSENQPASERNTGSSTEMEKEHDEFANQLADRARRVRERLTSYVESDRDSRSLSPHPVDRTREPSLPRPNPLGILRQKTSRGSLIDRNRENRVDSQHSKAIKMLGLATSTISSAPSPNKSSFEEKEPQSPVQEEREKPAFPRAETAPVLPTHEPEKDKEDDSMHAGLQAFRQARRRLMEAQKSPSSVPINPGQMPGSASVPMVGPPASRTAPSRERTPGPRSPSRERRPPPVTYQQRAPSEEAQPNNGPGRGPSRPPSRTERDRSGSEASSGDRPHRPARLRTGTISSPHEEQRGMVPPPTRPQMLNSPGLPGTNIRRSPIMPPQPYPVGAAQGKSLDRSASQGNLAVQYRRRGPDSGQPSPISPMAPIPSPSIPVSQSSPAFVPSRRPSAPPVPSPNMEAAPVSRLDESMKRVVRKKDISEPTFVSSTSRVPTVALPETSESRSRSGSRSRSGSILGAAASTPNLHGSVHANINAPPLPPINPKRRNMIGSMMGRRGDEDMGASSPHLPFSPPPIPTEHGGDSHSAFSVSDEEDGPGSQRRRLRKTISEANGMNMRARLTRGNSPPNMPAPMAMTGGLNNGNMPGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG13</accession>
    <name>A0AAD8UG13_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_756504</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360035.1">
        <property type="nucleotide sequence ID" value="XM_060514762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG13"/>
    <dbReference type="GeneID" id="85398660"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018045">
        <property type="entry name" value="S04_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01130">
        <property type="entry name" value="SLC26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="584"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="523"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1714573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="818" mass="89636" checksum="5A43273D3AC3A244" modified="2024-05-29" version="1">MAASKAGAVLAKILGIDLEASTRHQTQELHDHVVNAISPYDPYYEEDPTVKEWLLEQVPTKEGSARYVKSLFPFTKWILRYNTRWLISDAIAGVTLGLVVIPQAMAYALLARLSPEYGLYTSFTGAALYWIFGTSKDIAIGATAVVSLLVGKVSAKVLEEHPGEFQPEEISKSLAFLAGAVLLVFGLLRLDWIIEFIPHVAISAFVTGAAITITLSQTPSLLGIDGVNSKEAAYRVFINTARGLPRVKLDAAIGLTALVLLAAIKWYTERMARSQPKRKRMWEMLCSLRMTFTILLYTLISFLVNRGLENGEHKFRITGTLPKGFTHAGPPSLNTKLISALLPDLPATVIILVIEHIAIGKSFGRINNYTVQPSQELISIGCTNLFGPFLGAYSSTGSFGGTAILSKAGVRTPMAGVFNGAILLLALYALTSVLYYIPMASLAALIIHAVINLITSPEHIFKSWLMSPPDVFIYFIGVFVSIFTSLEDGIYVTVALSAALLLLRLARSKGRFLGAARVYQHPDHHASATPDHKDSDHHSISSSQTLSHNKAPPSPRLPASHDVFLPLDRRDGTNPAVQVNELYPGVFIYRFTEGFNYLNQAQYVDRLIEHVTHSTRRTTTPHYDHPGDRPWNEAVPHPSTVETDTESPSLLKPILRAVIFDCAAVNNMDSGAVEGLIDLRNQLDRWAAPEPVEWHFAGVHNRWARRALSVSGFGCPRTGYLEGWEPVFSLADLAGRPPMMCEQQVATTRSESACVANDSEQSSSSSALEQGVLGSKEGGVRHLAAVGAINRPFFHLDLPLAVESAIKSARRRDHRPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGR9</accession>
    <name>A0AAD8UGR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_585297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361470.1">
        <property type="nucleotide sequence ID" value="XM_060505834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGR9"/>
    <dbReference type="GeneID" id="85389733"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="76"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="28579" checksum="527E9D5D31C7B178" modified="2024-05-29" version="1">MGSIPTPDPIRLAILVTDEPLPSVSAKLGRFDTIFTTLLRNACESLDPPQTLESQLALTSYNVVAKDGVDATYPEPEDVDAVLITGSRHSAYAHDGWILRLTAFTRRLLDEGRVRVIGVCFGHQIVARALGAQVARSPGGWELSVTKLKLTEEGQDVFGSESLSIYQTHRDAVIDLPSGVKLLAHTKQCPIQAMYVPRRFITVQGHPEFSPFMMSEMLQIRHQAGIIPEEPFKDAMTRYSDAHDGVLIGRSFLHFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGT9</accession>
    <name>A0AAD8UGT9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_722217</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361353.1">
        <property type="nucleotide sequence ID" value="XM_060512452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGT9"/>
    <dbReference type="GeneID" id="85396350"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="132"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="49095" checksum="A1A7504769EF5406" modified="2024-05-29" version="1">MKVQKLLLLPTVSTAKSTGFPTVTISSGPIQGISTSRPNAVSPVNKFLGIPYASIPQRFCLPQAPKPWTDTFDAMAFGPACLQNFGINGKIPEVLEDLFNTPAPPGSEDCLSINVFAPAIRFLDAGLAVVVFFGFPNSPEIPQSEQNLVLHDQRLALPCVQENIASFGSNPSKVTTWGQSAGSFSVDHHLKAYANDALVPFPAAIMSSGQMSFGHLAHASSAIDAWTGLSSSVGCGNVTDEIRCMRAVPAENLISAMRKYRITFGPHFDNVTVLSKPIPLLMGTVEEEGRGLVNDKVNMTVFFNAYLPPPLISSEDLETIVSLYRSDTRVKNDFDLASAIYTDLLWSCPQSILASIAASSNISTWRYHFNTSILNLLPKEYEWLGKGVIGKFINSPSAGPGWPAVGSSYAPLEVATLGDVGDTSSVMKVSNSTSLDERCKLFDSIWPKLEVIEQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH11</accession>
    <name>A0AAD8UH11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquinol-cytochrome-c reductase cytochrome c1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_706012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361458.1">
        <property type="nucleotide sequence ID" value="XM_060511520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH11"/>
    <dbReference type="GeneID" id="85395418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="51268" checksum="5ACD578A212AC58D" modified="2024-05-29" version="1">MAYKNADLERVYCTCRAIFSGNDALLRRKKKVKEVLIKNTTTVKPLFISFGEQKTILMSQHLLECRVFESDLRAKVMFPSLFQSTPQQDADREASEVDAVRSVANALDEMSQSEGEDDDDELDHIPESYPEEAVLGPIAEEVPGDAPLADEPLALVEAITPPQDLANMCDIDSGVTLTSPPPHPGLPSLYPACLPYKTQHDILTTTQRVLEECCFDFATKWIPGVLQSQGWDCPSAVELTKWTKVFNRAGLNLPAHATTPAGTTIKDVLFRTRQLRHTAVHRQPTTAREISQHLRTALRVAKTLQDVSRAAQLEDLMSEVDEKIKAMVLTKNVLENRTLFSLDDIRRQREELDRQEKEMIENMVREDRDHKALIGRLLEAAVDDIFEKKVTRGQMLEEAENDAADIYYEASEDTVNGAVEDSDMSEGNKTPREDGKDIPELFEWDEALGFVKPVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH53</accession>
    <name>A0AAD8UH53_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_585404</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="4 10"/>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361446.1">
        <property type="nucleotide sequence ID" value="XM_060505845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH53"/>
    <dbReference type="GeneID" id="85389744"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000006">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF36">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042086925" description="Mannan endo-1,6-alpha-mannosidase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1719362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="457" mass="49313" checksum="7F93853B77E15754" modified="2024-05-29" version="1">MKFSSVARAATALLVSSGFASAAYSIASDDDIKATTKGLAYDLMSFYDGNLTGHTPGILPGPPPAGDYYWWEAGAMWGTMIDYWHLTGDSTYNDVVMQAMLHQVGPDRDYMPPNYTASLGNDDQGFWGMSAMTAAEDGFPNPPEDEAQWLALAQAVFNTMASPDRHDNTCGGGLRWQIPLSNNGYNYKNSIANGCFFNIGARLARYTKNQTYADWAEKTWDWMTSVGFIDADYNIYDGGHVEQNCTDINKAQFSYNNGVFILGAAMMYNYTDGADAWKTRLDGLIEGTLKIFFPNNIAFEIACEEHNTCTTDMLSFKGYVARWMSVTTQIAPYTADKILPVLKTSADAAIKQCTGQDNQRTCGFKWSSGVYDGTKGAGQQMNVLGAVSSLLIGNVKAPVTNTTGGISKGDPNAGSHSDNLLGTETPVTTADKAGAGILTFLVLGCAAGTFGWMSFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH77</accession>
    <name>A0AAD8UH77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_406297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363163.1">
        <property type="nucleotide sequence ID" value="XM_060502881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH77"/>
    <dbReference type="GeneID" id="85386780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="37604" checksum="E38BDCA55122AE2C" modified="2024-05-29" version="1">MSSTKGLALVTGANGFIGARTVEAYLLAGYSVRAAVRTQRSADELTAALPSQVASGQLSAAIVPDITVPGAFDEALKGVTSVAHLATPVSFINTNVEEVLGTAVQGTLGILESAIKETGLKSFVYMSSIVAIRGSSPKFQGRVVSEADWNDEAEEILEKAGSEATGHQIYGASKVKGERAFWDFKEKNKDRINFSMTAVNPVWVAGPPLILPEDPKRLSDTAIIAYRVMSGEEVPPVGPGNGTHVDARDVGRLIVFAADRPDVADGQRFIAGGNGNFANIQAYCDLLRKAYPERRDIIQEGEPGKGYLEDYGEPPESRRVDASKASKATGQGWITFDQMILDAAKAYERYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHE6</accession>
    <name>A0AAD8UHE6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_733199</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361694.1">
        <property type="nucleotide sequence ID" value="XM_060512911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHE6"/>
    <dbReference type="GeneID" id="85396809"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="58"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="376" mass="40882" checksum="63A45AA2350A7B9C" modified="2024-05-29" version="1">MAASMTGEQIQAFAYQLDPLAPKGLAPAVEFVAIILGIISVIVVSLRIYVRAGLSGASSRLWGVEDYLAVIGTLPFIPAVVFAVLASRYGVGFHDADLPSQLYLIRASEYQTYWEVLYFISSTIIKCAIGFTCIRLDRRKRVVICMILNMSVMVVVAILALIFVFANCTPLAATWNPALGSCQKKISLQTVSYIVSAIQMLTDWTCAIVPFFIVAGLQMSRRKKVSVIAILGLGIFASIATCIRMPYLKYYDTAKYPTEIAYHLGVISITSNLECSLGIIGSSLPPLRKLFKFYYGSSHDGNYKITGESGDALGSAGPGIKLGSLSGNDRTYHASAKRGTSRAGVREHETDDDDSSSRKGIIRKTDIHVSTSTFHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHH6</accession>
    <name>A0AAD8UHH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_719950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364437.1">
        <property type="nucleotide sequence ID" value="XM_060512232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHH6"/>
    <dbReference type="GeneID" id="85396130"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="110"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="362" mass="40889" checksum="ADDC84A7E942045F" modified="2024-05-29" version="1">MTVPRKVKDSQHAPGPVAGRLAFSATEYPGIDPQWVRLWNEHGGSMVRADEVELEHYRKDAVRYSFTYPSCRGPEVFHVEDRKIPVTTPGGKVSVRIYSPEGSGPFPVHLNFHGGGWVLGGLQSEAAWCRHMCNKSNIKVIDVDYRMGPEHKFPTAIYDCWDAVKWAIKNADALKIDPKSVSFGGLSAGGQMSAVLAHLARDEAIAIKLHLMIVPATDMRYCHRSIKQLDKSNCPYESARLYRDLPWGPLGREQWFLKYWLGEDDDEQARLLNNWILTPVLAPNFADLPPAHIITAEFDLERDEGEYYGKLLRDAGNEVSMKRYTGVPHAFAHYNHPERGLSKSFEFIADTAELLRAAHYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW0</accession>
    <name>A0AAD8UHW0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_627071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363182.1">
        <property type="nucleotide sequence ID" value="XM_060508607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW0"/>
    <dbReference type="GeneID" id="85392506"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="448" mass="45192" checksum="C8B0F13142222B41" modified="2024-05-29" version="1">MRPSAPLPLLLSVSTAANAIPLIDRLLHLRGTKPTKTYSVVNVEGSPSADPPVVTITRSPVQTTVTERITDTITQISSAVQTTSTSLIIVNVDGTTDSGPATVTVYPSVKPTPESTPLTVIPTTAATTPPVAPPASSADPAPSSAAPSTQVFESVQPAPSSTTTPGIPSSIASPSSTPSLSAPVVVPPPSSETLASPSQSSPVPSSPSTSAIELPPSTETPVAPSSAPVGSSTAIVMPPPSTETQGVPSTSPSASASVSTGAIEPPPSTWTSIAAPPASSSAAAFSSSSETNVVPPQSSATWAAPSEPVSTPVESSAVVVQPPPPTETPVAPTSYIAPPVEPSSTLPPNTTSSSSTSTTTTSTSTSTSVTEAYTPPTSTQVYETTYQTSWVQTPSSLPQPSTFVTSIISVTTSSSIPESTTSFDDGDWSTTKYPEWNGTASATPRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI33</accession>
    <name>A0AAD8UI33_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_753389</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363643.1">
        <property type="nucleotide sequence ID" value="XM_060514344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI33"/>
    <dbReference type="GeneID" id="85398242"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="10">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1723588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="91" mass="10246" checksum="8B73E7FDF76F321C" modified="2024-05-29" version="1">MSDDNISIYDEIEIEDMTFDEDMQIYHYPCPCGDKFQIALADLRDDEDIAVCPSCSLMIRVIFDKDDLPEDPEDEAEPAVEEASAQIPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UID2</accession>
    <name>A0AAD8UID2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_700156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364516.1">
        <property type="nucleotide sequence ID" value="XM_060511426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UID2"/>
    <dbReference type="GeneID" id="85395324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF2">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G04300)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="861"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1124" mass="125909" checksum="5A29F8CBF401A754" modified="2024-05-29" version="1">MFASPKGKSSATTIDLTAAPKKKTDIIDLTLDDDHETSSRPAEAGPPRKRQRTYYGPDFSVGPTGGFSEKLMQCLNAQVRPYITEALLNVPHDTFKIADIARRVLGEVYRSAIEDDVIDIDQGFLSQNAVKELAALARYRIADLCDNYEEYKKKPLSFGGITVPLHSDGYHGSRLASEQGPSTAPARPVPRPAPRPAKKQPRTKPPPQPRREPQPAPEVEHQPEPEHEYQLEPEREPEPALQPPATEPPIVAVSSTNYRTRAQARSFKSWKAHDSQAKAAFTPGHKAKVAWMTMPRRPYTTTEERETILRGTSKLVRNLPAAAALGSLPFHVDFTPDEMDDVRRIVRAMCDKKVKHKRRDNTDRELGKMLRKRPDLLTTIPPMIELKGTLAQRDHVAIRNFLDELANRHKRPARHPKVLTLEVDESDKQGEAQRTSQISALLLAREVNGNRGFGRMRRHINFTNEFRKAHEDDMEMRAEWVGCAGDIMTIAWTSDTNFICGATAHSDSHNQQYNKAGNLLLCSTTLGQLKAYPDHRIPRPIVEKGENSTEAMRESQSPWLYSSVVSSDYDRINNRAYTSSFDKTVKVWKVDDRGANMEALGTWTHAGNVNFVAVSKHESGMVATAADVSTQAVRVYRVDNDNVSQSPYQVYTGSRAWDEGNEETTATQKWAYFPATMQWGLAEGVRHLLLVGYSPRSLTGDDNDIPDDKLNTGEICLWNCLTGEKIKVLTASTQNVFEVVWHPTLPSFIVATSPAGLMVDDETLTQIRIFRPSLTPEGDTAFGEMQCLDCPAKDINELTIKPNTVLCSYVTAACTDGKVYVWDTSRGDKPIHALRHKKPIDEFDENLGKREDLDVGVKFTAWGTTADRFYTGGSDGVVKVWNVRNFRQPLVRDLLEAPGAIACGAFSPCYSRLAIGDASGRVMLLSLNKEDEPPAKFVLPPMPAGMRPRRPVRRPIPVIEHADPPAPHQNNQAQEPKTGVERGRRMLSSGQLIRHPDATVGVIQGPAYPTLGLHCPKSHFEGDASQPLLAKVEEIQQENQKMFRRKSLRVIRLRPLTDVGSVALERRHAHNVSRDLDLQELCEMTKLDLLMDQVNIDDPIYDEGWDYEYEEVNLEESIWATVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIZ7</accession>
    <name>A0AAD8UIZ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_583329</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362376.1">
        <property type="nucleotide sequence ID" value="XM_060505646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIZ7"/>
    <dbReference type="GeneID" id="85389545"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="94" mass="10690" checksum="1123AA86918F0DB9" modified="2024-05-29" version="1">MDSSRSALENSDLDKLNDKDKLELRQFLANEQQRSQIQSQTHALTEICWKKCVSGSIRGSKLDKGEEGCLANCVDRFLDVNFLTMKHLNNMRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ93</accession>
    <name>A0AAD8UJ93_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_322620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364951.1">
        <property type="nucleotide sequence ID" value="XM_060502381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ93"/>
    <dbReference type="GeneID" id="85386280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="56"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="64237" checksum="49CE712FF3FB9A2F" modified="2024-05-29" version="1">MSLKSSKHQPQLHAPYAMADFDDDCAWPRRLLHVPSMTSMQWSPGNYYGNDLAPRYIAISYTWGRWRLKSATQHPDVKGLPVKGVTWEMPRVDPDHFTMGEMENLLISALKLSTEVRAFDNPGEPVPQIHHVWLDVACIDQTRGSTEMALEVGRQAKIFKGATHTFAWLTTLSRQGYLSQTERLQQQAKLLRAEAKSGIERVQRGLEGTRQEIELLSLDPWFSSLWTLQEAYLCPQSVFISRQGELMSPSEIDNPAERPMLLSDFIDYCDHMMTIVTSHEKKPQTIDPNDKYLLALKHAIERSGMIGLRSSLPVTLLGAARHRTTTRATDRVYGIMQIFGFQLGKSRPGCDPHVEFSLPELEDELGRELLIREPIMSQMHIFEVPPQAGKRWRISPDSQPTRRLNYGEGKAVFDDMSVKAELSTVALKEVNWGHFSGKLCKFSTLVEIWNSKVGWTGGNIDLDGPEQWTAVHGPELARKEAIAFSQQHPNAVLLLLGLREIKAPPPDWSMPVGLLLVPFSGQPGISETSNVWLRAGICQWWTSTDPDHSPEVVGTLQGESEEWILSAGAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJB5</accession>
    <name>A0AAD8UJB5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Concanavalin A-like lectin/glucanase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362643.1">
        <property type="nucleotide sequence ID" value="XM_060514457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJB5"/>
    <dbReference type="GeneID" id="85398355"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF2">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041933731" evidence="1">
        <location>
            <begin position="19"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="255" mass="27856" checksum="DDD7003CBA3DD41B" modified="2024-05-29" version="1">MRSSLIASALVAVNPVLALTRSPAPTVTNGQYVVDGYAYAKRQIFNFASATTLPSGLYKSTWNISDPPTHRFDAANVVVGSGYMNLKVPGGQTAKPYSSAEVSTTFNVKYASVRTVAIFSEPAGVCNGAFFYQSDSQETDIEWLSDPASLSNQGTRKLWLTNQDADGDGVKTYNAISPPADPTTTEHEYRLDWTPGRVTWYVDGVQVWTTTDDVPSATGPWVFNNWSNGDKGWSAGPPATQADFKIKDIYMYYNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF3</accession>
    <name>A0AAD8UJF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_675910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362586.1">
        <property type="nucleotide sequence ID" value="XM_060511155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF3"/>
    <dbReference type="GeneID" id="85395054"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="44"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="473" mass="52741" checksum="CFCB2D656D1CFA8B" modified="2024-05-29" version="1">MSHETQSSTLATLHLLTQTLSQGSVITPDDPSYKLHSEPFAIQKQLYPSVVLVPSTIEELSSIVRFLYSSSLEFAIRGHGFKSPSAKDVIISMLNFKSLEYDSIRKIATVGASATWEEVVGFMEQVDPEYSVPAARTPSIGVTGSILNGGLSWVSSEYGGISDPINFLDAEVVKYDGKVVMASQEPGLLWSLRGGGGGFGIVTKVLLRAHPYPTDIWSGIVLLPRHLLAQMIDEVLKFNHSTPHPKVNYFMYLMPQQLLHTVLETPEPDIGDMVIFHVYDALGEEHGRATFRWVLEKPGAIDRTRVTNMKGVLNMQRNANVMRGTMKTLYAPMAVSDLDRVTITRAIEVYDNIAKLDQTIHDMSSVIFEFLLLRPPIGGTAEVAWPRSNNLNHLLLFIISCPGSGTDEQERLIRQISNDAPGQVLGPETRAEVNPAGLEPSYHDVKGVYREHYEKLVELRRLYDPKKRFQSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJG3</accession>
    <name>A0AAD8UJG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polyprenal reductase</fullName>
            <ecNumber evidence="5">1.3.1.94</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_427829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a di-trans,poly-cis-dolichal + NADP(+) = a di-trans,poly-cis-polyprenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:80727"/>
            <dbReference type="Rhea" id="RHEA-COMP:19536"/>
            <dbReference type="Rhea" id="RHEA-COMP:19537"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:231623"/>
            <dbReference type="ChEBI" id="CHEBI:231637"/>
            <dbReference type="EC" id="1.3.1.94"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:80729"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the steroid 5-alpha reductase family. Polyprenal reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.94" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362419.1">
        <property type="nucleotide sequence ID" value="XM_060503025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJG3"/>
    <dbReference type="GeneID" id="85386924"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160198">
        <property type="term" value="F:polyprenal reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102389">
        <property type="term" value="F:polyprenol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="218"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36425" checksum="65F5F7CCF9DBAE27" modified="2024-05-29" version="1">MDALSALPPAQWCQIFFGLSTAVVLAIQVVPKTTQRLLLDYGARSPANTTDTDDRTEEATGANGLDLFTQAAKAVTSFGQIPHAWFMHFYVASVAGSAFWAWQYIQSGSFMAIISARQAASGGPYVSFEQAVLVWTLMALQGTRRLYECLFVMRPGSSKMWFVHWLLGLGFYLCMSVSVWVDGSGEDCHHPLPDTHSPFPAALRQEARPNLEGLLSPGVVAGTVAYLCGWSNQHKCHKHLASLKKYSLPERGLFRYLICPHYTCECLIYLGLAMIAAPKGHIVNRTLMGALWFIVANLGTTADGTKQWYVQKFGAEKVASKWRMIPFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJP5</accession>
    <name>A0AAD8UJP5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAM1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Outer kinetochore protein DAM1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_576232</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365652.1">
        <property type="nucleotide sequence ID" value="XM_060504902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJP5"/>
    <dbReference type="GeneID" id="85388801"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990537">
        <property type="term" value="C:mitotic spindle polar microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013962">
        <property type="entry name" value="DASH_Dam1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28113:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08653">
        <property type="entry name" value="DASH_Dam1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="159"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1725597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="224" mass="24367" checksum="B5A14DF695321678" modified="2024-05-29" version="1">MADYDAHEKRSASRTRNSRPTTPMRPTTPLRPSSRSSFRESARDSVHGGGESFPLNTFEPAFAELSDAMADLEANMMHFQLMHESLARFSESFASFMYGLNMNAFCVDFQEGPVPESFKRAKLQEEMNAAAGSGIPRAFEKPSNDFDGETTFMTTDVSFVENPPASSKPTPKYKTPGTATRGSRVPAPSTRGGTTRGRAGGRGGSETTRGRGTGIVRPRGRGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK87</accession>
    <name>A0AAD8UK87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AhpC/TSA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_619637</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365521.1">
        <property type="nucleotide sequence ID" value="XM_060508139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK87"/>
    <dbReference type="GeneID" id="85392038"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1020.10:FF:000001">
        <property type="entry name" value="1-Cys peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000011">
        <property type="entry name" value="Peroxiredoxin PRX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1020.10">
        <property type="entry name" value="Antioxidant, Horf6, Chain A, domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF4">
        <property type="entry name" value="PEROXIREDOXIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="9"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="25320" checksum="D100A5F53EAD623F" modified="2024-05-29" version="1">MADQRPAPLRLGTVAPNFKADTTNGPIDFHDFIGDSWVVLFSHPEDYTPVCTTELGAFAKLEPDFSKRGVKLIGLSANTLGSHEGWIKDIDEVTGSKVAFPIIADKERKVALLYDMLDYQDTTNVDEKGIAFTIRSVFIIDPKKTIRTILSYPASTGRNSAEVLRIVDSLQTGDKHKITTPINWVPGDDVIVHPSIKTEQAKELFPEVRIVKPYLRFTPLPKEKATVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKZ3</accession>
    <name>A0AAD8UKZ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_629167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362435.1">
        <property type="nucleotide sequence ID" value="XM_060508751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKZ3"/>
    <dbReference type="GeneID" id="85392650"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="33332" checksum="0DFC04ED9823D383" modified="2024-05-29" version="1">MCYGCRRLGFAEPSPPPDPVHDREDEEPLPQPIDFDRPAPRKKLQPNPKTIVHSAPSHDGIPAFVAYSVPADTPEDADLTPLRPPYAYVFYDTSPGALIPGRAEDLARSIFDGTEDDRSSCGLPDRVEVFAMPLPPLPETGSPYSAEDVGLDLVLSRESPWYARLAARVSRDPQDAHCLQHAAACINHHEREVQNRLAIADRAEAVSWYLPEGLSDAEFTRHIVVVDRLEDKPKNPPGPTRWQETLAWTHSLPSEQRNPDKNRAERAESSPYGRGLLVDWRPRHQNEDDEDNEAHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL06</accession>
    <name>A0AAD8UL06_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="7">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_624994</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363930.1">
        <property type="nucleotide sequence ID" value="XM_060508476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL06"/>
    <dbReference type="GeneID" id="85392375"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="28940" checksum="A1A2BE49AA4458A0" modified="2024-05-29" version="1">MNCQRTLFRALRTVPRRHARAFSNFPVPGFPPVAGGGSSSSPPVGNIPLPYITEVSSNGWRTYDIFSKLLQERIVCLNGAIDDTVSASIVAQLLWLESDSPDKAITMYINSPGGSVSSGLAIYDTMTYIKSPVSTVCLGAASSMAALLLTGGEAGKRYALPHSSVMIHQPLGGTQGQASDILIYANQIQRIRKQVNEIMKRHINKSFGHDKYSLEEIHDLMERDNYLSAEEAKSMGVIDEILTRREEKDLKEKDSTEEHKTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL24</accession>
    <name>A0AAD8UL24_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hyphal anastamosis-8 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_268888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366312.1">
        <property type="nucleotide sequence ID" value="XM_060502039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL24"/>
    <dbReference type="GeneID" id="85385938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42069:SF1">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="58296" checksum="61F79D854D97E627" modified="2024-05-29" version="1">MASQEDRRRPAALNLAPARSASTDSSSSDSSLKPPRTPRFAEATSVHSPVDGVRSPFADPVRSEVPQSRPGDIGFGYINNSGGNRESVAVPMTPRSPLKSAMRVPGTPARKIVENPLSPTFREEDILEKREAATDKEQARDLKIKTRVRMAKFALRGVSFSCSLIIISMLAASFQIFNATKRLPAQSGLPSWAEGTAIWPQVLVITSKSRLQILNLRHFLTTFTVSSISLAVCIGVLLAYCRGGHQRAEKVATYYTLFAIGWFILSMVMWAIAAGLFQSSRSNGGGKDMWGWSCKENKRAEVFGEKVDYALICRLQNWALICMVIEIVIDVICVLLYSIVFYRYYTKRRLHKSMDMRDRARSDLYLAQLRSQSAPNTPGLKSPGLYSQYALSPRHPDKTFESLSRIEEAGASPFTPGTRFVEPESSFGKPKPAFQLQAPPTKARAATKPGQEAYTPTSPEGPGPAFPFQQQQQQQQQPSFHQEQPQAQQHAPMAADEPVYDAVPIPGAYADAPVKSPPPHQYSFGQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULH8</accession>
    <name>A0AAD8ULH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_741942</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363591.1">
        <property type="nucleotide sequence ID" value="XM_060513098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULH8"/>
    <dbReference type="GeneID" id="85396996"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="55"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="500" mass="56098" checksum="0765E35B796D6056" modified="2024-05-29" version="1">MGEPTSVTLSTPRPGTEEPINYGPPQEGIFKHISKIIPYFRDPRNVLVFKLDVMLLAWMFLAGIMKEMDQSATTQAYVSGMRESLSLYGNELVKFNTFFSIGYALGLVPGQLIQTRFRPSMFLPFCEMSWGLLVLFTYKAPNAQTIFGLRFFLGLFSSAFWPSVVALIFNWYTPAELAVRVACFTVCDVAGAMFLGALQAALFRDMNGVHGLAGWQWLFIIAGSVTVGQGLIAFITVPDSPANTRAIYLTENEKRLARERMGNSGVNTSKRIPASVLRQKLRKLIVHPVTYFYLFSFAFGAWAHRANSYFVLYLESIKDSAGNRVYDTYQVNILPLGGYALQIVTNIGLNWLSDWKRWRWQISIFSAAAHGICLAVLCGWPSDHKVILAFYFLTYGTNAGSPSLMAWMAEILRKEPEARSIIVALTVTVVYIGHATIPLGAFRVADAPRYPIGFPLTTAFTVATILTQLGMLWWDRRHPQMAEYGYEPAISAQGLQWRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULR8</accession>
    <name>A0AAD8ULR8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_672881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364169.1">
        <property type="nucleotide sequence ID" value="XM_060511132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULR8"/>
    <dbReference type="GeneID" id="85395031"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041969729" evidence="1">
        <location>
            <begin position="17"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="455" mass="48760" checksum="17FABEEAE6987CC9" modified="2024-05-29" version="1">MKTSATLLAFVAASNASPLGLSVKRDAFDSKDAMCKGWDLTTPEGADKLWEDTYAGASLDLFIKSQWEHENSWVKNLEDLVSGGTSGKSGAAGCSALGNECKPLNDMTCDAQYDAYGKTPIGKNSYWIFQAVKGMHAKFNELNRQLTKETLISGLQIGQMVTDFQGNQDDPGDVLGWLSAAASMGGAIGGLVPGAGTAIAGGFGMLSGIFSGLAASNSADEIDQGSISAALADAFKQATGALENTLRIATGGGTSQAEYDSLPAPKWDTFQSKITKFYNGGWFLVDDDEQAVTVALQSISNNIKPKVANDVMSAAKLYLVADRRDEVKSRETCGYATGRQWMALRDGEEYCFYIMRNNPNPGPDNDWVEVETDIYDKMASYGLGNRDPYYRAIIDCALNGGDDKDKVDLSNLAWGKVPTCYFNLPAMFIDKDTKTGCGSPFDSADCNYIAATPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM18</accession>
    <name>A0AAD8UM18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_718524</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="16"/>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366361.1">
        <property type="nucleotide sequence ID" value="XM_060512084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM18"/>
    <dbReference type="GeneID" id="85395982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12 16" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 16" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 15" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="18">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="272"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1726306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="477" mass="50602" checksum="FCF39FEA81687DA0" modified="2024-05-29" version="1">MLCAISGEAPQEPVASKKSGTVFEKRLIEKYIEENGTEPVTGEALTIEDLLPLTQSHVVRPRPPTLTSIPALLATFQNEWDALALETFNLKEQLARTREELATALYQHDAAVRVIARLSKERDEAREALSKVSVSAGATNGDAMAIDSAEGLPEEWIDKVNAKHQELSKSRKKRPVPEGWATSEEVALLTTVASTSTPVSNASSLATEGSYAAISGRSGDAAIYSIEADQVERQVAVNEPVVDSVWTGSKLIFATSKGSVKVFESGSEVASISEHAGPATSLSLHPTGDLLASVGSDKSIVLYDLNTLKKISRAYADSALTSSAFHPDGHLFAAGSVTGEIKLFMTTTLEVAAAFELGAPVEALTFSENGFWLAATAKGQSSVTIFDLRKEGDAAKVKTLETGGPVQSLAWDYTGQFLATAGAGGITVQQYTKSSKKWSEPLRTSVAALSVQWGVGAKQLVSVNEEGVVSVFGLKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMQ3</accession>
    <name>A0AAD8UMQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone H1-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_752387</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364694.1">
        <property type="nucleotide sequence ID" value="XM_060514196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMQ3"/>
    <dbReference type="GeneID" id="85398094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="7">
        <location>
            <begin position="275"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="437"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="54905" checksum="14F55C985372CA48" modified="2024-05-29" version="1">MADAPEQPTIAAEIPVAVAPIAEAPAVEAVANPEIKQDALAPTQQDTPATVGEEPEEDVNSKKVTLADLTAKGTALYAKKQYEEATDCFTKAAELQDEINGEMQPANAEILFLYGRSVFKVGQSKSDVLGGKAAGEKKAAKPKSKAPKKTTAEPASTDAPAETEAQRITEEGVAIVASETSGAKPEETVEEKKPLFQFTGDENFEDDSDDEEAEGDEEEEEEDDDLAVAFGVLDMARILYSRQLEELEKVEPNGKAQEQVDGEKLSIRHVKERLADTHDLLAEISLENERYPDAIEDSRKSLKYKKELYSEDSEVIAEAHFKLSLALEFSSVTTTQEEGEQGESKPFDEKLREEAANELEAAINSTKLKLQNKEVELATMASPEDNEVTRATITDVKDMIADMEQRLVELRKPPIDVNAALGGEGLGGILGAAIGESAAQTQARVEEAKKTATDLTGLVRKKAKEEPKPEETQANGAESNGTKRKAEEPAEADDSSKKTKVEEVTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN37</accession>
    <name>A0AAD8UN37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-ketoacyl synthase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_775788</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365912.1">
        <property type="nucleotide sequence ID" value="XM_060515454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN37"/>
    <dbReference type="GeneID" id="85399352"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-ketoacyl synthase C-terminal" evidence="3">
        <location>
            <begin position="11"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="30703" checksum="3CA109980259DFD7" modified="2024-05-29" version="1">MRSAAAWPGAVSITYPSTAMQQDPYHDLLAQTGIAAAQLGYVGMHGTASQAGDAANMSIVAAGFGSARSPGYLTHCTWALSRPTPATRGAAVAMASLIKSTMILKHRLIPVQTVPSSGRLELIRHLPPIHDLGIHGAGKSHVFRAARVGYDHKIMINNSDIAGVKVSLLLEEGSNLQQQQYEHGGDGRKYRVVVVSEHIPQVLRHERAGVPEHLRAHPQTSLVNVAYTATARRVQHACRTAYLSDSIKNLVPQLECNDNDDIPPVARSDAGADEHGSVVFVFPARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UND7</accession>
    <name>A0AAD8UND7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_792937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364309.1">
        <property type="nucleotide sequence ID" value="XM_060515769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UND7"/>
    <dbReference type="GeneID" id="85399667"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF5">
        <property type="entry name" value="DEPENDENT EPIMERASE_DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00180)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="33266" checksum="DF35374A4BC09788" modified="2024-05-29" version="1">MTSQTPRKRIFLTGASGYVGSVITELAVKDGFEIHGLSRNEASDSKLRNLGAIPTRGDLTSLDVFRHESKAADIIIHLATAYVFGGEPYETFRPIDTAAVDAIADALAGTDKPLVVTSGTLCVAADPTGAETTEASPADPEPINTRILTELHSLGLAKRGIRVMSIRLAPYVYGRGGSGVAQFMGIAAQTGGVTIVDGGKNRTTNAHVDDAARLFLLAAERGRTGEVYNASSSTDVTSFQISEAISAAVKVPLRDINLDVAKEQLGQTISFFLSAENRASGAKAKEELGWEPRGLGILEDISKGSYMEVAKALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNQ2</accession>
    <name>A0AAD8UNQ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_778276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364953.1">
        <property type="nucleotide sequence ID" value="XM_060515502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNQ2"/>
    <dbReference type="GeneID" id="85399400"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042113161" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="120"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="62569" checksum="114E05AE72110177" modified="2024-05-29" version="1">MTPPRIAIVLITLIVGSVQAESCKCSPQDPCWPPASNWGTLNRTLDGRLIQFNPPGSVCYTSQPDYNQEACDSLIVQYSTWAFNSANPASMGTKDACDPIYPNGTSIFGDTHAGATGCSLGTLSPYVVNATEAGHVKAALQFAEDHNLRLNIKNTGHGGKLSIWTHHMKYFVFHETFQPVGCLNTSKRDAPMAATIGAGLQDGELFEALAGHNAFGTGGTNTDVGVVGWSTGEGHGFMTGAYGQGADNIIEASVVTPSGDVVVTNECQHEDLFWAIRGGGGGTFGVILNLTLKAYPMPNVTLFGINAVAKNGTSPKSWWEFVARFHTIIPALQDQGLHGYWSMDAASRALGGSFFLWNADNATVARVTAPLQEFFKNSSDSITYTAAPIKLTTFYDLVKQLPTLGDMSRNSATSASRLVSRDLLTQNQTAFAETLEKLAENNTQDSISFSGTMTISSKPVNNSLNPVWRRASIHLIASQSYPATLSSIETEKVVSDMTFNKLNLLRELDPSSGAYLNEANDLEPGWQWSFFGENYGRLFTLKNRYDPNGLLWCNKCVGSEQWVTVKNGSLCPAYAFHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP13</accession>
    <name>A0AAD8UP13_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_651073</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365700.1">
        <property type="nucleotide sequence ID" value="XM_060510425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP13"/>
    <dbReference type="GeneID" id="85394324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="13">
        <location>
            <begin position="22"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="14">
        <location>
            <begin position="135"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="15">
        <location>
            <begin position="257"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1725645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="43974" checksum="BA76CA868ED84AD0" modified="2024-05-29" version="1">MSATNGVNGNGIASRKHYNEGNFLFTSESVGEGHPDKIADQVSDAILDACLREDPLSKVACETATKTGMIMVFGEITTKAKLDYQKVVRDAVKDIGYDDSAKGFDYKTLNLLVAIEQQSPDIAQGLHYEKALEQLGAGDQGIMFGYATDETPELFPLTLLFAHKLNAAMSAARRDGTLPWLRPDTKTQVTIEYKHDNGAVVPLRVDTIVVSAQHAEDITTEQLRKEIKEKIIKKVIPEKYLDDKTVYHIQPSGLFIIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFSKVDRSAAYVGRWIAKSLVNAGLARRALVQLSYAIGVAEPLSIYVDTYGTSDKTSDDLVKIIRDNFDLRPGVIVRELSLDRPIYLQTAKNGHFGTNQTFTWEQPKTLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPN4</accession>
    <name>A0AAD8UPN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinase A anchor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367258.1">
        <property type="nucleotide sequence ID" value="XM_060510313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPN4"/>
    <dbReference type="GeneID" id="85394212"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019510">
        <property type="entry name" value="AKAP7-like_phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009210">
        <property type="entry name" value="ASCC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13360:SF1">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10469">
        <property type="entry name" value="AKAP7_NLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="A-kinase anchor protein 7-like phosphoesterase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="27267" checksum="C6B3E90154707A6A" modified="2024-05-29" version="1">MPPRPNARPSPTHFLCIPLVTPASRPQLSKSLASFRADVTSPDSFAIPTDAVRPLGTLHLTLGIMSLTKDEGISKATEVLKNLKPRDILADITPLSTETPLAGKAQSSTSAPGTDSPLQITLRGLHCMKSGPRADPSKASVLYAPPAYGEGGFQTFCERIRATFEEAGVMEKDARGLLLHATIVNTIYVKGGWSKKGPKLTIDARDILDRYDDYVWMEDVPLEKIAICRMGAKKIEGTDDEAYEVEAEIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQV9</accession>
    <name>A0AAD8UQV9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RhoGEF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366735.1">
        <property type="nucleotide sequence ID" value="XM_060504674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQV9"/>
    <dbReference type="GeneID" id="85388573"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45818:SF3">
        <property type="entry name" value="PROTEIN VAV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="250"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="917"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="969" mass="107377" checksum="0EE2DBE91D818333" modified="2024-05-29" version="1">MALPPPPPPPPPDSASLGSCSRSSSVRITRKTVCAISNPPSPGSQQDSIKSDEVFENVDLSSGLDGLHISGVEAWNTLSSMAGLGLESNNGDSHDDLIPFPRISVDGSNDDDHELSDSDTSSRRGPFHKWMKTLHRRAKQRTQPMNGDGALPWKLLDSADRSALSRRTRHRRSSSGSSFGFVAAVKSASVSLASGSAITRPRGSSRRSLVYSKTERSSRGSFTAARFSEDSCNVEWPAQVDPSATERALQRRRILEELISTEEGYIADVRFLMNVYITILASLPTLPPGLRSSINRNLTDIVELHEELLGELHRAVPDSEYTQVEIPSLPRKPPSRGHQRMRSLDSVPEDDDRAISWLREVPGMISEAQVAGDVAKVFSRKAIAGMNRFFIYEEYGAKYEMMIKDVASAHRTMPQWDTYQRGIETLASSLGSANSHADQAKKSLTIGDLLVKPIQRICKYPLLFAELLKHTPVADCPNSHMEVESALLRLREATAEINRATNDRRMKSTLERTWVLQDRLVFPEQKLDAASKNRIRSFGHVELCGALHVCWQTKDGAKGQYMICLLYHSVLCLASASKVDQIYTIQACINLANIKIEETDNGRGLQCHTAPFSWKLGFECDSQLYEILMTACSPREQEEWRSRLSVARTGEQEQIDPSLYSSMSLNMKSTVARRISIHRATTVGPKSPLCQVILKNTSVMRDNSDAASTTSINRSQSLLTTNPRIPILAPPRGERARLEALMSDIWSRDILPFPGMTGRSRSEHLVRSSASTMMRKLSVASIASSFAKRSNSVASMGKLVPDENVGEKQENARHGQASKLCREESSNVEHGLDDEAGETTKTRLPKIDDDVEVISTVSAPATPMLNPARILVHADPVEQLRLQHIYSGDTYTSRPSILRTASGNNLPRVRRDQITARKSPCPSEKGVYREHQSRAPKGPKLSHKASMRWGKVGTLNRDDLVQGIRSFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQX3</accession>
    <name>A0AAD8UQX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_651208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365629.1">
        <property type="nucleotide sequence ID" value="XM_060510435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQX3"/>
    <dbReference type="GeneID" id="85394334"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="255" mass="29123" checksum="ACB880881553A4D8" modified="2024-05-29" version="1">MPHFNSGNYNLSPGQLPWSAEMSEWFVSHHRVILQPPRHSVSYGGSEARLAKNIFVVRSWDAQDPPREPLAIREDLAGNIAWHTISQQPLSEPRIESISLHVDVLERWQRGWIKWHEQHASPDDDDCIYGELPGDDDVYHSEGSSSKGEEQDDENDDGELSYCCDTDRSKRGLPLVIEAFNKEYTTIHDYVSTLHPWLMGSRQDISRTNNLMGDRTSGECESLVVDVANLDYLSTMDQKRFPRSGYTGTRFCLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR10</accession>
    <name>A0AAD8UR10_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endo-chitosanase</fullName>
            <ecNumber evidence="10">3.2.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_577667</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin. Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endohydrolysis of beta-(1-&gt;4)-linkages between D-glucosamine residues in a partly acetylated chitosan.</text>
            <dbReference type="EC" id="3.2.1.132"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 75 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.132" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364895.1">
        <property type="nucleotide sequence ID" value="XM_060505042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR10"/>
    <dbReference type="GeneID" id="85388941"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42061:SF6">
        <property type="entry name" value="ENDO-CHITOSANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041771413" description="Endo-chitosanase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="28341" checksum="DBED0B8139AD6EE8" modified="2024-05-29" version="1">MFHNFAYACAFATLLAVPATARDVPANVEAFYDQFRGRQQCSNTLKTGFHSKEGGKGDYSYCGDYLSNYNVVYIQGSGGRLTNMDIDCDGTQTHGDGRCGSSTDTQSQTSFKSEIQDYQAGIKDLNAYVHPYVVFGNDGSKPGWPTFDPKKHGIEPLSIMAVVCNNQVVSLSPIPFIYGVWGDTNGDDGSQAMVGEASISLATACFGTGMNGNAGHDQTDVLYIAFPGKDAVPGAQGAKWAAGSYDEFEGSISALGNRLLKRIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USL0</accession>
    <name>A0AAD8USL0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365705.1">
        <property type="nucleotide sequence ID" value="XM_060504869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USL0"/>
    <dbReference type="GeneID" id="85388768"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="2">
        <location>
            <begin position="65"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1226" mass="137469" checksum="84BCBBC9C327B867" modified="2024-05-29" version="1">MADFRKLALEFVLSDDTERQTAITKEAASEIQSAPRPSNPVARWVESIRPWMPSANEDQDDGDGDVIARSKALSFLAGTLEHLDSAFLKADQTNLLVAFFGSMFKVDHKAGIMPAAEALNRTAGMKTFQPQKGNDIIQSVCSLGDDFKSQVAETRATVYELLDHLITNPDVANDLQYQHGTTSGFITDLLQLCRNERDPKCLMTWFKILKVFLSDYSPAPEVVDEIFSIFSAYFPISLRTSQHPSGITADDLKLALRACFSAHHRVADKAIPYLLSRLDQPDSVSVNVKVDILKTMTACLSGYEHVQQGVTPFTNKIWDSLKYEVRNGEIEDTINATLEVIRTVAKRLTGDELRDFALTVQRDCLEDLSNPIYTAASGKLLISIHSAKPAAFALMISPSVTHIKENLRHTKSPDHTKNLLILLNSLLELRLALIGGDVELSVEDAEAFKSTEPLLAPIYKQTYLPLFQKALQDTAQPEDITIGQQATKGLGLMVCQRAAQTGQSNQPMLPEETLNEICDNLATLALQAPGELAKDRNQLKTSDEAAIALQKATMAHPPAQPVLIDTCFRVCDAYSASPSANNLDSMRNVLKHNLARLTYIFCSESPRSEKLRLYTYFMQALLVNLYKMQDAKADPKIWSVIATYIFSAMIQFKEGAKELIYLPVKNNFSDTRFDYNWVSYVANRFPNLPCLPDDQIISMQAMDESNEVDNLQGDFALINLYVTRQLYRRATKIISYADNSELSLALSDDFGKKDPEEKNEEDAYLQRLSDIAVFTIQHMSEYQQTNLLLNEEVVTLFRGTDQYHHPNPNETHSWNNSELRAAMLRTMGLPQTPYNMRDPPQFPISGFSHGRTVILSLGIIQAFHPTTVERLVERGTAHQILIAGLLTRDHSDSPKCRHVVSAILSVIANKYKVENLNDIVQIMEYQMNFVVSEERLSDQLEQITGYLDHEENVVAGNSPNDLRASLTRPVYAIVVGILRRYTGNALKNVLTAITQGPGNKKIGHTLARNMDFIFSDLDFAKPQFYGQLKKLWVQRAYYELVKPMLPKAWPAGSNSKDDMLVAANYSIAVLRAVRHITYAHYEDDTEDLIRIILCAIRNLPASADVAAGLQILVAVTENSPRRMQPFLKSVIDASLSIFRKNTTQAGEDNTWMPENYMPFDRSGFQEAQCRALVVRLIGQLPPNFEHRHLLDSASQAKRLLAQASGDESRMVREAALKSRKAWDEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUY3</accession>
    <name>A0AAD8UUY3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Non-ribosomal peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_570963</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368219.1">
        <property type="nucleotide sequence ID" value="XM_060504363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388262"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000003">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056896">
        <property type="entry name" value="SIDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF3">
        <property type="entry name" value="SIDEROPHORE SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24895">
        <property type="entry name" value="SIDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="780"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1427"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1949" mass="213389" checksum="B0E339D6968125F9" modified="2024-05-29" version="1">MHLRDSEGGGTAYQETSLIDGATNGLTNGNSTVNPSSTRTVVVTSRAESTTTAGVSDFRHELLLAWLLVLHRNNDDGLSKVNWGFRTRDGQEPSSATHNSLSLSEAPFKNSDSIAEALEVIKELGESGLGSETRTIPVIYFNNGAPKSQGNSEKAPSKRSQDWTYQIEATLNENQLVIKAQWDRAVLSYRHAIFQLDSFIEILTTILEKPYRQVSDTIGPTAKDLEQLWTWNAELPENMQKCMQDIISEVAAKGPERPAVESWDGNFSYGDVDRLSTRLARHLVARGVTVGSTVPMCFEKSRWTTVALLAVMKAGAAFALTDPSQPEARLRTIVEQTGATIIVTSQNQSDLGRRIAPEQTLVIASDDTLNNDTLELAAELPVVPPSSPLYIQFTSGSTGKPKGVMISHENFTSGAVPRGWEVGYRAHSRCFDFASYAFDVSIDCMLCTLAAGGCLCIASDEDRMNDLSGAIRNSKCNMAHMTPSVARVLDADVIPSLEVLGLGGEAVSAGDASTWSKTTSVIIAYGPSECTVGCTINGNVSSTSTNIGKGTGGLTWIVDPDDHERLMPVGAVGELLIEGPVVGMGYLNDKAKTDEVFIEDPAWLLAGGGPARGRHGRLYKTGDLVRYDPDGTGSIAFVGRKDQQVKLRGQRIELAEVEHHLRGKMPSGVKIVAEVIKPGGSEPTLVAFVVEQNPVNGPADAEAGDVTTFSPEFSQAIAEIDIALGAEIPRYMVPSAYIPLRKMPSLVSGKIDRKRLRELGGSMSREQVARLRVAPTEKSEPETEMEKALQQVWIKILGSESAAAIGLHDSFFALGGDSLRAMKLVAAAREDGIALTVATIFNFPTLKAMAENATKVSKEDDAAVAPFSLLEEGWTPEEARAESAKLCGIDESAIEDIYPCTPLQEGLMALSAKVTSAYVAQRVVDLADAATADKLRNAFNVAAADCAILRTRIVQVPGRGLAQVVVKEDIAWHIGDDLQGYLVKDREEGMDLGRPLVRYALVKDNASGKVQFVLTMHHALYDGWCMPLIVDKVNKAFDGQKVQRPAEFKDFIKYLGSMDRSAAETYWREQLQGAAATTQFPALPYEGYQTQADSLLEVYVPLNGRPASNTTVATVIRGAWAYVASHYASSNDVVFGETLTGRNAPIRGSDEIEGPMITTVPFRTQVNAETLVSDYLQDIQDQTIQQIPYEHTGLQHIRRLSPDALEACELRTGLVLHPSADDFDQEEFNKYPANRLVPAGDAEAAEEALKFNTYALMLVCSTDPKGFLVMASFDSKTVQKPLMEKALAQFSQVAQKLCQLTDTPLGDIAYLTEEDKTEVARLSTESAKSVQQEYPEAEAVYIVNPTDSALLAPLGVVGELVVVSKSDLSLSTLENPSWAETKEAGKFYKTERLAKFNADGPVEITGKTSDLVQKASTATKAPTKRISATSAKQRRLRTLWSRVLRLPESDIGLNDSFFRLGGDSIGAMKLVSEARLAGLTLTVNQVFTKRTLYDMASVLQDSEPTQDSQESLKPLVPFELVENLGDAPAETLCPLLADPTWKIVDAFPARPLQEVAVKGTIEIPRFSARYEAMYFESDVDRPRLFQSCQELVSLNEVLRSVFVKHNGACLSVILEDVKTPVVEYEIDSDVETFVKDLCNMDVQTRMPLGSIFVKWFFVHSSNGQSALVFRVSHAQYDEICLPIMLHQLSALHEGKPVPKALPFSSFVGHVVKSNIPQSVDYWKELLQGSSVNVLKPDTPVTERQHYAIDRTFDISTRSKDVTIATLPTAAWALTLARLQSTRDVTFGEVVSGRNIDFLNADMVVGPCWQYVPVRVKFEDDWTVLDLLNLVQNQHIASSAHEGIGLPEIAKLCTDWPASVDWFDTVVHQDVEHVESLGFETASSRMETIYPQQEPLREWKIQAFPQGDKLTIEIVTFESWKGHAAELLDKIEETFKILLGNPRSLLFEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVL7</accession>
    <name>A0AAD8UVL7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DlpA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_716937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368673.1">
        <property type="nucleotide sequence ID" value="XM_060511895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVL7"/>
    <dbReference type="GeneID" id="85395793"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="105"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="24282" checksum="CE5F30DA88A42D06" modified="2024-05-29" version="1">MTNTHDERIAALQKFTACDISDALVKLKVPGAGFLPDLQLLSQPNPADAPITIAPASTILFVRKGETWDSPAANIPKNTHWADITQPGTIVIIRQPDGQKNAVCGGIMAVRMKVRQAKAIVVVGRARDLDELTSTGLPVWSRGLSTVGAGAESTPWAVEVPVNVDGTVVNPGDLVFADPVNGVVVIPKDKVDQVLELLPKLTAADDKVKADVLNGTSVFDAFKAHRSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWV7</accession>
    <name>A0AAD8UWV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_113635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368644.1">
        <property type="nucleotide sequence ID" value="XM_060501110.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85385009"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057948">
        <property type="entry name" value="TPR_TRIP12_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1352"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="556"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="904"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1042"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1146"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="587"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="939"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="965"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1073"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1156"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="1714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1747" mass="190985" checksum="0E1AA7533D929579" modified="2024-05-29" version="1">MTGTDDAEKESLPLPPPPPPPEHHDDDDSDDNDDDDEGQRYDDDVDDDPFGGFGGPGGPGGLSSTLRALTGMMTGISSRLRDLLNSLRQKDDPSVQLIALQELSEILLVSNEDNLSGHFSPDAFVKELVTLMQPNEMTGEENPELMLLACRCLANLMEALPASVANVVYGGAVPVLCQKLLEISFIDLAEQALSTLEKISAEYPSSIVREGGLTACLSYLDFFATSTQRTAVTTAANCCRNIPEDSFPVIRDVMPTLLNVLGSSDQRVVEKASICVSGIVESFKYQSAKLEELVSVDLLKAVLRLLVPGTTNLIGADIHTQFLRVLAFTARASPQLSADLFKLNIVETLYQILTGVSPPSGTEDVASKLDSVVIMQALIHRPKEQIIETLNVICELLPSLPRNADPSYGDFVEMNATEPITPSSTAAGKTRKSPNDKRIELLDSCKAEVRRFALILFPTLTDAFSSTVNLNVRQKVLTAQLKMLSNLDEEILSEALKTVSYASFLASILSQQDHPSLVMLALQATELLLSRLEDVYRYQLYREGVISEITKLAIEEHTPPPAPEPAGSQESHNTEQQAAADSGDQSSDNEESEDDEEHEESDDEENDEDNENEPHPDDISGSPVSSRGSTMSLDGPPQHFLSDVPSMRSRIREVAKKFLESHETEKHGKAMKKKATKILTNLSDLAEEIEAFYLNRSAGNLSPENGVELFKKLASSFDADVLESVTSAELLASGLVRVLLEVFSNPDEDLARTAQADFLQVFMGYSVKSKPKTATADSPATPFSVMVHKLQDLLSRSEHFEVITVHQNTFDGNRSSAASMLAKQIRLRLVADDESIPKSYRNIMVSIHAIATFKSLDDYLRPRISLSERPRGSSRRADNLSRALASLAGSAGLPLSHAAARLAERASAASGSSPIPPPPSVPTPSGSRSLRKTKSKSTPQSETAATPDTSSSTRDKGVLRRSTRRSAASAADSPVPSRPPPEEDDLENALECADEKHLSDDEEIGGSSALDAIVGDLDEDMSESPGPEPGAVNMEIAAGGKVTARKDDGTRVPTPSQSSLPTRSSALPPPPAAQSTPTPATSSRPMSYAAAIQAVPQDWHIQFTLDDKVITSETTIYRAVHTSAANSDEHFSRSVWSAVHPIKFRRAPGPPPAETLSFSSNAQASTEENGEGNVPASLAKHPSTASILRLLNILHDLNANIEDVMVENSEKDAVRLNVEPLSQFVNTKLTAKLNRQLEEPLIVASNCLPSWVEDLARLYPFLFPFETRHLFLQSTSFGYARSMTRWQNAHSADDSRRDRRDDRPFLGRLQRQKVRISRSKILESALKVMELYGASQSILEVEYFEEVGTGLGPTLEFYSTVSREFSKKKLKLWREMDSNDSEEYISGASGLFPRPLSDDEAIAPNGERILQLFKTLGKFVARSMIDSRIIDLNFNPTFFRIGDGSSAPGVKPSLGAVKVVDPGLARSLKTIKKFAVAKKEIDEDPSRTPAQKVADTEDIVIDGVKLDDLCLDFTLPGFPEIELMPNGGQIRVTIDNVDSYLERVIDMTLGTGVRRQVDAFRTGFSQVFPYSALSAFTPDELVTLFGRVDEDWSLESKYFPVCTPNDILTFSLALMDSIKADHGYNMDSKTVKNLLQTMSELSAPERRDFLQFTTGSPKLPIGGTFLSTSSTCFKQTRLTQATGFKSLTPMFTVVCKPSEHPYTSDDYLPSVMTCVNYLKLPDYTNIEAMRKQLSTAIKEGQGAFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7E4</accession>
    <name>A0AAD8X7E4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chondroitin AC/alginate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_725183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000303">
        <property type="protein sequence ID" value="KAK1702685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357175.1">
        <property type="nucleotide sequence ID" value="XM_060512724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7E4"/>
    <dbReference type="GeneID" id="85396622"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alginate lyase" evidence="3">
        <location>
            <begin position="90"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1702685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="43747" checksum="6290AD9DE67CA171" modified="2024-05-29" version="1">MKFTSISRASLWAPEADALCSNSSQPTFKHPGLLHTAKDFDRITGLVNAQKEPWTTGWSKLKTRANTAYTPNPKETVCRGGAGRECNPENYPSLYRDAHAAYTNAIAWKITGDEAHANASARILDAWSDSLIYINGSSDKFLASGIYGFQLANAAEILRGWNGWDGLSAMTEMLQRVFYPMNHNFLVNHNGASIDHYWANWDLANLCTMQAIGILTDNKTMYNEAVGYFKNGAGNGAIKIAIWELHKEEGSGKILGQGQEAGRDQGHALLDFAFLGVFAQQSYNQGDDLFSYLDNRILAGSEYAAKYNLGFDVPFTNFTNSHGTAVNISESGRGGLRPIWELLYNHYGVIKGLNASWTEQMRDHVVEEAGGAEGGGGDYGTTSGGYDQLGFGTLLYRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7N5</accession>
    <name>A0AAD8X7N5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_550936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000340">
        <property type="protein sequence ID" value="KAK1701744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357053.1">
        <property type="nucleotide sequence ID" value="XM_060503489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7N5"/>
    <dbReference type="GeneID" id="85387388"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="120" mass="13129" checksum="BFE1C0722AE21627" modified="2024-05-29" version="1" fragment="single">GPPPDGGVKAWTQALMAHFVVINTWGTINSFGIFQTFYRDHISRSDSEISWIGSMQVFFLFVVGVFTGRLTDAGYFRAVFASGSTLVVLGSLTASFSTQYWQLFLSQGLCMGLGINFPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8F2</accession>
    <name>A0AAD8X8F2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase/isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_156128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000196">
        <property type="protein sequence ID" value="KAK1708406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358284.1">
        <property type="nucleotide sequence ID" value="XM_060501364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8F2"/>
    <dbReference type="GeneID" id="85385263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000009">
        <property type="entry name" value="Carnitinyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="27955" checksum="EE578FA0E28048D1" modified="2024-05-29" version="1">MENLTTLKLTVDSEKGVALVRFDRPAKRNAFSQVMIGELVSTLAHLDALDTIRAVVVTGGPEGPFCAGMDLNELVQISTAAAHQRAFLKDLTDAFANFSKPIIAAVVGFALGGGCEIALACDMIYAAEDASFGLPEIKIGTIPGAGGTQRLARALGKHKAMEFVLTGDSASGAEFERLGVVNKVFPRQEVVPAAMKLAERIAVMSGPVTQTAKQAVLTVENSHLDAGMTMEKSLYYSTFSLGDFNEGMTAFLQKRRPDFKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9I1</accession>
    <name>A0AAD8X9I1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_639591</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000159">
        <property type="protein sequence ID" value="KAK1711539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359092.1">
        <property type="nucleotide sequence ID" value="XM_060509438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9I1"/>
    <dbReference type="GeneID" id="85393337"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000025">
        <property type="entry name" value="High-affinity methionine permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF382">
        <property type="entry name" value="LOW-AFFINITY METHIONINE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1711539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="58564" checksum="C6362238CA57692D" modified="2024-05-29" version="1">MSSPLKHDHHVGEDRHVVRDDASGEEVGVVKQQEVYAFDESRKIGVTGAVFLILNKMIGTGIFSTPSGIFQSTGSVGVALMLWVIGGVLTFCGMSVFLEFGLAIPRSGGEKNYLERAYKHPKYLATCVLASQMILLGFSSGNSLAFGRYILFASGSESPDGWTARGIGIAGATFAVGIHAITPKWGIRLFNVLGVFKVIVLLFIVFSGFAALAGRRRVPNPHNFDNAFRIEEGEGYGNGGVYGYATALLRIIYSYKGWENANYVVGELKNPRKTLAIAAPLAIGGVTILYVLANVAYFAAIPKTELATSEVIVAGVFFRNVFGNSAGARALPAFVAISNLGNVLAVSFAHARLNQELAKEGLLPFSTFWASNKPFNAPAAALFLHWIVTVIVLVAPPAGPAYNFITDLYTYPGAWINAFVGIGLLYLQWNKRENWTSPWHTYFPITILYVLANVFLCIVPFIPPTGSWTAEGYPYYVFPIVGVGVLLLGGVYWGFWTKIFPAIGGYKVVAERTYDEEGHEVIRYRKVSTKHSHSGPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAF4</accession>
    <name>A0AAD8XAF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360067.1">
        <property type="nucleotide sequence ID" value="XM_060514754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAF4"/>
    <dbReference type="GeneID" id="85398652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="11146" checksum="EAA73F87EAFBA087" modified="2024-05-29" version="1">MAREGTRSQTGNSKPRLFPVVDTAPVRKQNTATTTTAKKPKTTSTAAKAAKPVGVTKKKATTAKKGPSVATKAKSVAKKAETKVAAATKAGKKETKPKTTKAKATPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBH0</accession>
    <name>A0AAD8XBH0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YDG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_631815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361599.1">
        <property type="nucleotide sequence ID" value="XM_060508923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBH0"/>
    <dbReference type="GeneID" id="85392822"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YDG" evidence="3">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1719515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="13556" checksum="81DB1A61CD0FAE59" modified="2024-05-29" version="1">MTPRASPSLIPAFESPCPPKNPSQLSAAWYGGHGDSNAGISYMRGSTGEPGPAISIIMADKYSDIDVDRGDDIVYCGANSLDNTSRNTLADRRPPLRRNAETCSKMLQETSTDNSRSCSKDTLNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD99</accession>
    <name>A0AAD8XD99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_756104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360488.1">
        <property type="nucleotide sequence ID" value="XM_060514701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD99"/>
    <dbReference type="GeneID" id="85398599"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000008">
        <property type="entry name" value="Glutamate carboxypeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="197"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="6">
        <location>
            <begin position="390"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="5">
        <location>
            <begin position="670"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="796" mass="88001" checksum="C469DB600CDAC7AE" modified="2024-05-29" version="1">MSDERTPLITNVYIGAPRRRYPNHVLRRFCTVALSSILIFWSIFFVVALFVDEPPRHHGHHHHGWSWTNSVNSAPITHEEVQKILFEVPSSEKAEEWSRYYTAGPHLAGQNYSQAAWTKEKWESWGVQSEIVSYDVYLNYPIDHSLSLLSKTKEEESSWTVEFKAALEEDVLEEDPSSGLEDRVPTFHGYSASGNVTGSFVFVNYGTYQDYEDLVKANVSLEGKIVIAKYGGIFRGLKIKRAQELGAIGALLYSDPGDDGKVTEENGYEAYPNGPARHPSAVQRGSAQFLSQRPGDPSTPGYPSKPGAPRAPVDDATPSIPSIPISYADALPILKALNGHGPSVKDFNKYWNRNLGLKYKGVEYNIGPTPDNVVLNLYNEQNYTTTPLWNVIGIVNGTIPNEVVVVGNHRDAWIAGGAGDPNSGSAVLNEVIRGVGVALASGWKPTRTIVFASWDGEEYSLIGSTEWVEEYLPWLTEASVAYVNVDVGVRGPNFNPSAAPLLHRVLREVTQLVPSPNQTVPGQTVADVWDGRISTMGSGSDFTAFQDFAGIPSLDFGFGGENGDVVYQYHSNYDSFHWMKEFGDPGFVYHRTMAQILGLVVAELANVPVIRFNATDYADALTGYVDQVESKLAATIDDADSDEDALFRMRATVAVADADAKGSLSQFRTSLQILRTSIAALREKTVRLDTKAGEVDWELKYGSIPWWNLYRKIKLALAFVWVNRSYKGFERNFLYPGGLDGRTWFKHVVFAPGLWTGYSGAVFPGLQESIDAKDFNNALKWTGIINECIASATKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDZ1</accession>
    <name>A0AAD8XDZ1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase lambda</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_632701</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361268.1">
        <property type="nucleotide sequence ID" value="XM_060508990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDZ1"/>
    <dbReference type="GeneID" id="85392889"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000001">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="19">
        <location>
            <begin position="197"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="292"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="381"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="428"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity" evidence="17">
        <location>
            <position position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR622312-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1718768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="831" mass="94130" checksum="8BC8228D779EF7FA" modified="2024-05-29" version="1">MADANTSFRDKARFFRQLESIGRQGEDGEDDDDDFHEAEQRIRQQLRAFQAAAQLRHPLRERPQPELQSPLLPPPRQQEQQQQPQRRVSPRRTSSAPVSAPLTELKRKEVIERTPLAEIKGLGRKEAPTEDLSFVEDTPIPETLARPPLQPLVTLTRSATTPLSLTRHVLPHRVDNSPSIAAMKKRKREPPIKLLPEAQQIFRGLRFHFIPNDDIAPARKIRIRKSQEFGALWTRSLDNATHVIVDRRLDWKSIENVLSSASEGSSYIVLNEDFPLDCIRFKTLLNAKQKQYQVSGCPEPPHSPTSPEPKTSPHTVQPSIGPTARDLPLKKRQTNPKKWDYAPPPSTPSRSQESSGRTSGIATVTAEPSVLRDITEAVQSTATSEAAFPQDAGSYEDVPATAEKPTSTSEDELEHVISQLQQFRDLPLEHDDDDEDDASATSPQSYEQGSGSEGSDDELQRKRRAVARSRGRKEMTWEDKFTCHKGGTLGSDQHNPNFRTIEILQQMCSYYERINDTWRPIAYRKAITQLKRQPAKISTAEEAIRLPGVGQRLADKIEEIVTTNRLKRLENAESDPMDEVLQKFLKIYGVGSIQASHFIAQGFRTLDDLKQKAKLTVNQRIGIDHYDDLNTRIPRPEMKWLSAVVRSEAAKLDPTVQIIVGGSYRRGAQSSGDIDFIVTKKGTRASSELITFLRDLIEALEAQRFLVARLAGSRDDDGSKWHGCCVLPKIEGFNDQEYRKVWRRVDFLVVPEAEIGAALIYFTGNDIFNRSMRLLASKKGMRLNQRGLYKNVMRGPGRAKLTEGELVEGQDEKKIFDILEVKWREPHERWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE19</accession>
    <name>A0AAD8XE19_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PIN domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_356022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364389.1">
        <property type="nucleotide sequence ID" value="XM_060502549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE19"/>
    <dbReference type="GeneID" id="85386448"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09906">
        <property type="entry name" value="H3TH_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09870">
        <property type="entry name" value="PIN_YEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000037">
        <property type="entry name" value="Rad2-like endonuclease, putative (AFU_orthologue AFUA_3G13260)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000051">
        <property type="entry name" value="Rad2-like endonuclease, putative (AFU_orthologue AFUA_3G13260)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041177">
        <property type="entry name" value="GEN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037316">
        <property type="entry name" value="Yen1_H3TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF75">
        <property type="entry name" value="ENDONUCLEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18380">
        <property type="entry name" value="GEN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="108"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="474"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="519"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="609" mass="67306" checksum="1EF6B412536C6FDD" modified="2024-05-29" version="1">MGIKGIYRELGPGKRVSLAKLATEKLENTSRPLRIAIDIAIWQFQAQAARGGTNPAIRTLFYRLVRLLSLGIHPIFVFDGPHKPAFKRNKRSGKGDGLAIAMAKRVIRLFGFLVHDAPGEAEAECALLQQRNIVDAVLSEDVDTIMFGCTRSLRNWSAEGTRGAKTPTHVSMYEVDSLLSAETGLDREGMVLVALMSGGDYIPEGVPGCGPKVACEAAKAGFGKSLCRLKIEDDDQFDEWRRTLRHELRTNESGFFRVRHKALSIPDEFPDRQVLRYYTHPVVSSAATIDRLKADLDWSRPIDVQGLRYFADETLDWVNKIGAIKLTRVLSPALLAHKLLQRHLSDQASYQTAVEMEKEESKLVNRIAGIRSHHSTDGISELRVAHIPTDIVGLDLSQELDEADEVPFDRQGLGLNSDEEFEAVIDGEGVPTSSQAVPKSTFDPYAAQMIWLPESLVKLGAPLAVEDWEEKQRAKATKVSTKPKNTSSKGFGKRKPAKAVPAEAGALDRWMQITKGTTTRQSAKTGGATSQHQVEDEDVLSPHIPRPTTLRPDPTKITAAFPASSFSSQRPSPLLRPINRKPPSLGSPQSRFCCHLAPSPLRLRLLFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEI5</accession>
    <name>A0AAD8XEI5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_581042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363431.1">
        <property type="nucleotide sequence ID" value="XM_060505416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEI5"/>
    <dbReference type="GeneID" id="85389315"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="37"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="640" mass="72722" checksum="6FD2265867427193" modified="2024-05-29" version="1">MQTYLRDPSRNSRHQPNIGGQCANGTCRGGPHGGGRRKLILCFDGTGNKFRGDDSDSNILKIFRMLDSNANDQSGIGTYVVSENLTHNGVRAKCKSWYQMAKDSAVGSSFDQHVVGGYRFLMRYYSPGDDIYMFGFSRGAYVARFLAEMLDFVGLLAHGNEEMVAFAWSSFSQWQCRRTNSTPEGKEDREKMYQFLKGFRETFSRPIRRIRFLGLFDTVNSVPRFETAWMQRSKFPYTARSSAKVIRHAVSIDERRAKFRQDLIYQEPKKSRRKTAAKRLMEHHHPLNEKVQEFQEKYRPGRRSTLAPDDAVAKEDRGRRRVHPQEEDADHPAPFRSRSRSRSRATERTGNAYTDHDASSINSKPPIEDLTYDSDDDEADQDVDEVWFSGGHGDIGGGWDAVSGQKNASHIPLVWMVREAMRAGLTFDLDQLEYLGCVESVAGADTRTARQSSATMPNEAIAVPEIHVDAPSPTIDFQPASPTASATENVVNSDTSTHTCTALPFNVMMQSAHEAKIHDSLDFTCGMHRASVFMWRVMEYLPFRRLDLRPDGSWKPIRWPLPRGEVRDVPDKVRIHGSVLRRMERDEKYRPGNLIVGGGGRGCRVAPKEYGIGHWKCVKGSGDIIDEIWEREWETEQKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEN9</accession>
    <name>A0AAD8XEN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_440959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362003.1">
        <property type="nucleotide sequence ID" value="XM_060503105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEN9"/>
    <dbReference type="GeneID" id="85387004"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="25177" checksum="57E125038E828AA7" modified="2024-05-29" version="1">MGFQGEMESGADLSGIRAASRTILSPFFHGHSPSSPRVSTGRHVDGISQHSGCVILFCHLYFLPSHFCRVAYIILMSDISLALLILNPERLFTRLYVRCPWCCWNAGMIMAIAFRATQARIQSKRQFRSCYNLQRLAGLRMKRTLITAEKKHPLVSSQQRPNCLQLLDSSVMMVLSALFVFGSPKTRALHTIDILTLAPHRVWQQNRLNSYPITLENGTKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF47</accession>
    <name>A0AAD8XF47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_777980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364987.1">
        <property type="nucleotide sequence ID" value="XM_060515494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF47"/>
    <dbReference type="GeneID" id="85399392"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="168" mass="17820" checksum="613B10A58E48650B" modified="2024-05-29" version="1">MAPSLEQRVIEALEKCSTDADTPFDDVLRVALEVTQKMLEQVDPPEIVTPVASAASSVPLIAQIAPPASALAPNSTPAQAIASPAAPGNTNTPAARGVLRAALPLAMASARKRAAREIVSPTPTVGDETDNKNEFVCEFAGCRRSYEHKGSRTRHYKVNHGGQRPRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG83</accession>
    <name>A0AAD8XG83_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NAT10</name>
        <name evidence="15" type="ORF">BDZ83DRAFT_614736</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with TAN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG83"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11040:FF:000002">
        <property type="entry name" value="RNA cytidine acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="12">
        <location>
            <begin position="10"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="11">
        <location>
            <begin position="281"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="537"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="14">
        <location>
            <begin position="774"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1016"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1048"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="636"/>
            <end position="638"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="643"/>
            <end position="649"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="738"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1726794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1061" mass="117850" checksum="99539F54D555AAE7" modified="2024-05-29" version="1">MSRKAVDQRIPSLISNGYQEKKRSFFVVVGDHSKDVIVNLHYLMARNIKQNKSVLWAYKTKLLGFTSHRKKRENKIKKEIKRGTREANESDPFELFVSLHNIRYVYYKETEKVLGQTFGMCILQDFEAMTPNILARTIETVEGGGLVVLLLKGMSSLKQLYTMSMDIHSRYRTEAHDDVVARFNERFILSLGGCDSCLVIDDEMNVLPISGGKGVVKLPPTDKDLNKTEAEQELEEMKESLQDTQPVGSLVTLAKTTDQAKALLTFVDAIAEKTLRSTVTLTAARGRGKSAAMGVAVAAAVAHGYSNIFITSPSPENLKTLFEFVFKGFDALGYADHADYSIIQSTNPDFNKAIVRVNIHRAHRQTIQYIRPQDAHVLGQAELVVIDEAAAIPLPLVRKLMGPYLVFMASTINGYEGTGRSLSLKLIKQLREQSRPGAKTGEDTEVADRTTGRASKDQGSSQSSRSLREITLSEPIRYAQGDSVEKWLNKLLCLDATLPKAKASAQGCPDPSQCELLKVNRDTLFSFHPIPEKFLQQMVALYVASHYKNSPDDLQLMSDAPAHELYVLIAPTSDGKLPEPLCVIQVALEGKISRQSVINQLSRGQRPSGDLIPWLVSQQYQDDEFASLSGARVVRIATNPEYVSMGYGTKALQLLTDFYDQKFTNLSEDADLAMEETLPRVTDAELSNTSLLADDVHIRDIKKLPPLFARFSEIRPAALDYVGVSYGLTQPLHKFWKRASFAPVYLRQTANDLTGEHTCVMIRPLENTGADRSWLGAFSRDFQRRFQSLLSYQFREFQSVVALSIDESASIGAKLDGTEPTALTKVELDRFLTPFDLKRLESYANNMLDYHVILDLVPTLAGLYFTGKLKGDIKLTGVQQAILLAIGLQRKDMDVISTELSLPSSQLLAMFIKILRKITTHFGSLVNAAVEAELPSNNTIGVSRENASGVHDDEVVDKKFVPLETSLEDELEEGGDEALAKLRRKQRELIDSLPLDQYEVDGDAPAWAEAEQAVKDGKTGVVSVKSAKSKRKAGPTAAGIYDEALGEKKHKKAKKSKKDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGB5</accession>
    <name>A0AAD8XGB5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_620704</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365246.1">
        <property type="nucleotide sequence ID" value="XM_060508209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGB5"/>
    <dbReference type="GeneID" id="85392108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="193"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="38741" checksum="C0DABEC168E1F8E2" modified="2024-05-29" version="1">MRTFYVTIVFYNAALAGIKMTFLFQYYRVLAVQKMKKVFIAAMVIVGAWSISQILVEIFICTPIPAFWDKTIDGKCIPNYPQWYINAAGNIITDIIVFVLPLPVIHRLNLARGQKYVLLGIFCLGFFTCTISFIRIRFLKLEEDFTWQNVETAGWSIGELCCGLVCACLPTFRPLVSRFIPALSSRIAKSSKYHKNGDYSENTESTSRHRDPELGGTLGNPNHYSARYSKRRTGSADSKADLYGIASYDLSHSDASREAGLPIRASRDSPDFTSQTDKMPSPLRQQESIELGGYRPNHHAIVETRIEAGRRVSDDEIELQPGAPIEVKCDIVQVSSQKVEARGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGG0</accession>
    <name>A0AAD8XGG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Maltose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_695323</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367089.1">
        <property type="nucleotide sequence ID" value="XM_060511356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGG0"/>
    <dbReference type="GeneID" id="85395254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="23"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="54962" checksum="4152685A20C3D095" modified="2024-05-29" version="1">MAVVSEKPAGFAELSKNKRVLAWCLLIFILPINFGYELALVGNILAIPAFLDRFGTTTTSGIKEIPAHDQQILNASTTVGIVLAAYCTGFISDIIGRRMVVICGCILCIAGIIVQGFSNSILMLFGGKLISTVGYGLGHALGPVYVAEIAPNSLRGVCLILINTMIVIGQWSCALVGYGGSFIRSDWGWRLPVLAQLAPPFLMLVLGGILLPESPSWLLMKGKREEAGKSLRKFNGPRHNVEESLAIMEATLGKEKALSQGGASYLDCFRGTNLRRTTIVCVVYLTQQFAGAQLVVGYLSYFFTIAGVGNPIGIAQVCYSIQLLGNICSWFLVERVGRRPLIVWGTVAMTALLLVIGGLGVPKSNQSALTAMVALMALWGFISQLSIGAVGYAVGGETASPRLRQKTYSINVMSNTAAACLVTQLMPFLINPSNANLGGKVAFVFFGPSLLCSIYLYFCFPEMKGRSYLELENMFQKRLPTREFKNYRSEIETIEVDDGEKVAVVLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHE3</accession>
    <name>A0AAD8XHE3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_717234</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368139.1">
        <property type="nucleotide sequence ID" value="XM_060511923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHE3"/>
    <dbReference type="GeneID" id="85395821"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000004">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.810:FF:000001">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="349" mass="37935" checksum="5F66A1B078FEE103" modified="2024-05-29" version="1">MAPRLPSSCLQLLRSTTTTISNTCSAAANASAVIAPRLQLLPFTAKRGVKYGWSTAPKRSKPTRFNQPTAGLPVLTTGPAAALARREKTTPLRTGVLAVKKGMTAIYYGKKRVPCTVLQLDQVQVVANKTRPDNGYWAVQIGSGSKEPRNVERPMLGYYEAKGIAPKRHLAEFKVRTKEGLLPVGAQLFPDWFQTGQYVDVRSNSRGMGFAGGMKRHGFAGQEASHGNSLNHRTIGTTGPSQGSGSRVMPGKKMPGRMGNERVTVQNLTVLKVDNELGVVLVKGAVAGPKNCIVKLQDAVKRKAPALPYRQDKLKELLEANVDGEARLQEARERHLVLKKERKELPALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIW0</accession>
    <name>A0AAD8XIW0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365170.1">
        <property type="nucleotide sequence ID" value="XM_060514146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIW0"/>
    <dbReference type="GeneID" id="85398044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="22577" checksum="911B5216F205B225" modified="2024-05-29" version="1">MLDVDADLMFLYLGLAHRQFNKTPEFGRMFGIISLAHFPHVADWTRLIKLCQLFNFLQNNELLRSAWSVLSFNTLTALIYLLAPETDGAEVDRCFDAFARAFDTLDVDHPAQAKFRDEMVARFCEHCHCDLLVRHHQALESHPDFVAKVSLKQAEYAASMMQYLSGSPRARGKRSGLWRSKARCWDHLMRQRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIX4</accession>
    <name>A0AAD8XIX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_614856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366878.1">
        <property type="nucleotide sequence ID" value="XM_060507870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIX4"/>
    <dbReference type="GeneID" id="85391769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042266451" evidence="1">
        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="109" mass="12582" checksum="D4DF8FD5D76999AA" modified="2024-05-29" version="1">MGHGAWFSWLLMSVRLLLNVEWRTLGLFGIEVEIKGEVGDLGYVGFELGLSGFCFGRCRWWWCFSLSCNGVGAYVSGRTFFFWSVSVFSSLRGWLRLKIEQSPRKRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ3</accession>
    <name>A0AAD8XIZ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_309877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365335.1">
        <property type="nucleotide sequence ID" value="XM_060502303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ3"/>
    <dbReference type="GeneID" id="85386202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="141" mass="15588" checksum="529A1C5823078FA9" modified="2024-05-29" version="1">MMLPPIMQPAKLPFLFHIAIETAAACSFILRPGSQLTNPPAAAQLVLQQFGGLLLTTNLICLIFVSRPFDEMSRQVAAALAFWHVWPCWRAYVRLTKPEVDGLGKERGEEAKATQRTLGGPAVHLAVHVGMFLLFARTVFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJN2</accession>
    <name>A0AAD8XJN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome subunit RPN7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_648522</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368618.1">
        <property type="nucleotide sequence ID" value="XM_060510187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJN2"/>
    <dbReference type="GeneID" id="85394086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000013">
        <property type="entry name" value="Proteasome regulatory particle subunit (RpnG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000021">
        <property type="entry name" value="Putative proteasome regulatory particle subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="229"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="54007" checksum="A4A4A26149E285CE" modified="2024-05-29" version="1">MGSEPQYAKYPLLPLAQHVFALTNAYASRPSQQSAAKALNDAITEHKMAPLYRYLAHPLEGILNQVGEGGSQTPGKPLSRKSSLAGMIATKTTPTAVNLPWDEARYQELKADNDKELEEFQKEEDEAVEKAGETEIQAARGKRAEFWARVGDKDRAIAAYEDVFEKTGILGTKIDLVLAIIRMGLFYGDKLLVKKHVERAKTLVESGGDWDRRNRLKAYEGIYLLTVRSYNLAAPLLLDSLSTFTSYELCTYSSLVVYSVLAGSVSLKRVDFKSKVVDAPEIKAILGDGEDKLLALSGALSAGPGADDAMHDAPPAAAKTAVNLTTLGTSTDQPEAEMAIDFSPLAQLVSSLYNGQYKYFFQALAQVEESFLTQDRYLHEHKNWFIREMRLRAYQQLLQSYRVVGLETMATDFGVTVDFLDRDLAKFIAAGRIPCTIDRVSGKGVIETNRPDDKNKQYQDVVRQGDQLITKLQKYGQAVRLRGSERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK45</accession>
    <name>A0AAD8XK45_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_103013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368873.1">
        <property type="nucleotide sequence ID" value="XM_060501042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK45"/>
    <dbReference type="GeneID" id="85384942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="94" mass="10271" checksum="DDED893C40D3035D" modified="2024-05-29" version="1">MNIRYGVVANMMPSHLSERLGIAPSSILGFGILLPFSRTMLLLSVILTYFSSSCCQLDIILLLFARMSVFFFVGAALPLCDALALSYNAGYVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK47</accession>
    <name>A0AAD8XK47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_569294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368906.1">
        <property type="nucleotide sequence ID" value="XM_060504176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK47"/>
    <dbReference type="GeneID" id="85388075"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024645">
        <property type="entry name" value="Mitochondr_Som1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11093">
        <property type="entry name" value="Mitochondr_Som1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="128" mass="14405" checksum="6DBBFDDC7829F4AE" modified="2024-05-29" version="1">MSPPCAAFPPSKLGVHVQADVKGKKRKLPIGADVDLTKCALKEMTQYRCFVENSQSRNSPVRCWPIHRLFRQCQDKKGTFMVETTAWEGSKSDPTTRHNSQATGNGKSQDGHSSEPAYHQWSQAWEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKJ7</accession>
    <name>A0AAD8XKJ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_716512</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369099.1">
        <property type="nucleotide sequence ID" value="XM_060511854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKJ7"/>
    <dbReference type="GeneID" id="85395752"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.330:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.70:FF:000008">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013992">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018106">
        <property type="entry name" value="CAP_CS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01213">
        <property type="entry name" value="CAP_N-CM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01088">
        <property type="entry name" value="CAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="369"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="528" mass="56515" checksum="D5DA0687C30201BB" modified="2024-05-29" version="1">MATNNMHNLTTLIKRLEAATARLEDIATSTIELPQAVPALNQSVASPPAASNASAPPPPPKAPATPQAPPEPVPESIEEFDQFIATSVDKYVKTSQQLGGLVADQAAKVLQGFQAQRNFLLITTKAKKPDLNGAEMAVYQDLLKPINEALVAVNNIKESNRGSPVFTQLSAVAEGIMVLAWVTVDNRPYKHVEDSLGSAQFFGNRVLKEQKDKDAQQTEWVNAFYQVFRDLADYVKQNFASGIPWNPKGQPAQEVAKSLSASAPSAAAPPPPPPAGGLPPPPPPPGPPPVLDIKEETPGAKGGLGAVFSELNKGEAVTKGLRKVDRSEMTHKNPSLRTSSKVDGEASARGKSPAPGKKPKPESMRVKKPPKKVLEGNKWTIENFEKEPQPIEIEASISHSILISKCSNTTIIVKGKANAVTIENSTRLSLIVESLISTVDVIKSQNFALQVMGAVPAVLMDSIDGAQVYFSKESTDTKIFSSKSSGINLNVISGEDEDYVEVPLPSQICSYYDESKGELVNEIVSHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKP2</accession>
    <name>A0AAD8XKP2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein smt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369203.1">
        <property type="nucleotide sequence ID" value="XM_060513639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKP2"/>
    <dbReference type="GeneID" id="85397537"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19417" checksum="8865816DF903E603" modified="2024-05-29" version="1">MPSSSQKPDVTSSLSKLSINSNKKTPSTKKTKAPVADSWEDEDVDEDDDEEEEEEAVRPQSDGAKAPPPTPISPTYNAADRSFPNPYGSVDSVAGAGASSGGGGQDAASSRPRPEKTDAVARRMIASALGVKVPRMTEEQRAYDKAVKEKERKRREDEKAAEKRRLEDAEKAKVAIWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB9</accession>
    <name>A0AAD8XLB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_34683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369582.1">
        <property type="nucleotide sequence ID" value="XM_060502492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB9"/>
    <dbReference type="GeneID" id="85386391"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="186" mass="20633" checksum="579461C80F0889E1" modified="2024-05-29" version="1">MPLLPRQTTTNGVVVVPATYGGWSSLGAGAIVGITLGAVAGFLLVLWMVYTCLNFGRPVEASSSSVYTGTASVVSVRRQRSKSRHRHRKHRSPRARVIATEEVRVRESVSRPPAPGGPIIVEAAPPPPMQERRHSRAPPPRIVTDDEEDEVVVIEEHSPSDRRRRRHSSSRRHSHRGESRRGSRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLW0</accession>
    <name>A0AAD8XLW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_16778</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369835.1">
        <property type="nucleotide sequence ID" value="XM_060501435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLW0"/>
    <dbReference type="GeneID" id="85385334"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35179">
        <property type="entry name" value="PROTEIN CBG02620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43835" checksum="BB241CCF58785933" modified="2024-05-29" version="1">MAGTLIPPWYVGSTPTNDEQNIASMFWGFTLGVGLWSGVKGYRQSRASWNRTHRVNVYIWLIWAEWIASIVIGIISWCYLTSIIDPSFEYFFFLLVLWTIQVQCLMQIIVNRIAILMPIPAQATRLKWGVFGILLAVNISVFCIWIPARLQINETYIHINEIWDRIEKGIFLLVDAGLNLTFIYLVKSRLIASGLTKYTALFRFNLAMIAVSMSLDVILIGLMSLPNTLIYAQFHPLAYLLKLHIEMGMADLIAKVVKASNPMRPHAETRRDSNEGAPDANKNSLSKSRSRRFSVPYVAGRWMLSFENVQPKRNTTGPELELGIQANTFSGRATEPEITPRPRSLSRHITEPHGIPGLDMTPQSRTSRQDSSSTVREQDQDVAWYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLZ7</accession>
    <name>A0AAD8XLZ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_603875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369945.1">
        <property type="nucleotide sequence ID" value="XM_060507248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLZ7"/>
    <dbReference type="GeneID" id="85391147"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918580" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7556" checksum="86C40F3E161CDABD" modified="2024-05-29" version="1">MLALRSFLAAALSCFSSLLAAARLSRWLCLRSIFFSVRVRGGQLCRVQSLVGTGAQSGLGSRIVFLPLPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM80</accession>
    <name>A0AAD8XM80_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_452642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370043.1">
        <property type="nucleotide sequence ID" value="XM_060503165.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387064"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700">
        <property type="entry name" value="YALI0E22418P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1278"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1285"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1365" mass="146974" checksum="CC2DFCF2055C235B" modified="2024-05-29" version="1">MEGFPRINRTMSAGPGPPKSPAPHPPRRGQSVTAGRLTRYRSVREHKSVLDFGRNWRDWEVDIFQDDETVSNATTETGTATSIALGLGIGIAVDEEEGATGGVDDGQATVSSPHPHDQYGQQQQQQQQQQTPASSLRRRRTAPLLSTPVPQTPSGAPQLTMQWQWPDLMAGTGISDASSPFDFENSPVSSGRCAATGEGEGQGGGRSASYYCRGGGGIGTDIGSTGAGDGAVGGGKRMVVPAPPESPVRFSYPNRRRPTKTAPKADLDDSWSPLHGSSSPPFFSSSPPSLSPKSPTTTTTDARSSPPAGGGRASGVLTGATTDACGPYGPRPPSEPGSLFSLAPSYSGSTSPAPGVPGVSSTQAAPLYALGPCPPAPSAGSVLLPPASASAADASASTSASSASWSAAPKPNLVGLVPQPPTPLTTVPPTPPRLPTIPAVPVVRAFALAPAFAPAPVEGSQGTAPLEPATPPPPVPHHPPPPPPPPHSLLHPTQPSPPGIGLGLLPLPIPVQGQAKVQAQAHHTRARDLVPPPGPHLRPRSHNPILVSSHSSCADLKLAARAEHARSQIITKLALQPDSNNNTEYTSTNKEGLIRSNNPHWDQQLARQEEDRQRRRHQQHQQLLAQQEQQEEEHRRRKEQEEEDAARWAEEVARLEAETDRILADQKAKDLARLQAQLAAVPDAPASRVRTPIVDKFAFFLRKGRKTEPANTLTKPPSQYFQPLTLDHRPVSVMDPSRFIQAGGGGIVPQTDAPTSASNAGERRVTIRCMQSSISLPVTPDTTPSEILYSAANLMTHNINPQTSVVLECYFAFGLERRLRRYEPVALVMNSWDRDTQHCLLIVPGESTDKNPDLNLEGVPRTIDPPSGLINFALYHSQRPGKWNKRYITLLETGQMFSAKKKDAKLSDKDAVSLCHLSDFDLYTVTEKDMLKQIRAPKKNCFAVKSQQKSTVFQNTENFIHFFATDDAKLAEDFQKVIQGWRSWYIANKIVDLNKKKSSSHSSSARSGTKTGGGGGLTRSGTLHRPRASADETPYTIGTFSPLLDMNSFEKPIDDFGKDLDNKPTARHADHHSTPRHTQSHKVVSRSRTTPNLSQPHTRRLIDPFAKDEFKSGGLLGQAYEGRKQQAEKAALTADHQQYAVESPFTGGHSLLGQFPEHENSGMPQRRGTVRSSRPTAADPMPQPRSRSRPPAARPTTSSRPKTSDGGSSSGKREMPQPLVDLTPKVPDLPAAWRDGQGRGVRVPTGKPLIEMATGLELPDGHLGPQLPTVTRMGTAKAYPPQRMASQSAASRPRSRSTAGGGAVRRVVSNEQQPPMPSMPRRSSRRDDEDVPLINFVERERGRDTRPRMSQGMSQGLGRSGTVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMH4</accession>
    <name>A0AAD8XMH4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_715861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370087.1">
        <property type="nucleotide sequence ID" value="XM_060511791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMH4"/>
    <dbReference type="GeneID" id="85395689"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000396">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF4">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="607"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="137"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="713" mass="78529" checksum="3D4EF0B006BDA1C6" modified="2024-05-29" version="1">MAGVLTWKSRFGGVFGNKNKSDSAEATDDENTNIPKWSMGVLNDPKTIEVPGSVLLLAAHRNEPLGLRNAPARTSHSSIPTGFPEPVDTPTGRQSPANAAPPEPDAKTTKDGIILNPQPEESANDPLNWPSWRRDCALLSLGFYCMVGGGMTPLLAAGFTNVAEDYHIETETVSLTTGLYMMGMGLGSVIFSPTAILYGKRPVYLFSSVIFILSSVWAALSPNFTSLILARIFQGIAVSPVECLPSATIAEIFFLHERAFRIGIYTLLLLGGKNLIPLVSALIIQGLGWRWTFWIVAMIVAFCGVLLFLFVPETFWDRTPLPKSRKPSRRPSFTRRFSSRHHVPQVHNAHEDAVVAPTSPTPQSPHVASHPHKDLHVGFAPDPNEKQDDSIDKQVKDAKNDTPDSSNPVPVSRTSGASGTPTSGSDYFHNAPAVESEKFKMQASDVNSPPKALAYTHTLRHQPAKSFTEQLKPWNGRLNHDSWFKVMLRPFVLFAYPAVLWSAAVYSLSVGWLIVVSESVALIYRNRASYNFDALQTGLVYLSPFIGGILGTAVAGKVSDIIVKAMARRNGGLYEPEFRLVMAAPVLVTTVIGLMGFGWSAQERDHWIVPTIFFGLISFGCTLGSTTSITFCVDSYRQYAGEALVTLNFSKNIFHGLVFSLFVTHWLTSDGPKMVFIWLGVIQLIFLIATVPMFIYGKRARMWTVRKNFMEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN58</accession>
    <name>A0AAD8XN58_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_726339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370538.1">
        <property type="nucleotide sequence ID" value="XM_060512757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN58"/>
    <dbReference type="GeneID" id="85396655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="1">
        <location>
            <begin position="155"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="57515" checksum="33D61BEDA1F18FFE" modified="2024-05-29" version="1">MSGIEVVGVVLGTIPLLISALEHYRHGASAIRIWRSLITDLENERIRLQDVSEKLLTGIVPDSKVDDMVNDPFGPSWHEDAVRKMIEARLWDLRPYQILLEKVGEIKLAIEVIAKSINPPLNGKNNITDIESLIDRSIGMAPRRESRARGRTMQLVHELAGSLHQALLSSFPGNCSHEVYMQVMPQTLGRVARRSDEEILQNIDVHMSMNFGIADQAGGFHQGSMWEEIVIRYHQPKKPRRSVDTNKPVGNDVLQAAPDSDTKVTIAAPNPIVNLCEKIRKRQIQGGTGSYREITDKTSEKPREYRVYPGKCLPGRDAWSAVALREVLEDPSKYSGLHGQYVAKRKSAASISVGFLQLHQTHWLPDMVTSHDVLFLKKDALLRYGDTFVMATLPSLDGRLGKQAAPLFGCRNPALVSLGTLLAELGCGETAESMRNTDEKAMLGVSRLLCDRLAAYRVLRHELGGITYANAVRCCIEEEFNREHLDLTDQDFWQEVYERLVRPMEDEQYGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNT2</accession>
    <name>A0AAD8XNT2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_331796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370762.1">
        <property type="nucleotide sequence ID" value="XM_060502421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNT2"/>
    <dbReference type="GeneID" id="85386320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="28985" checksum="8C3FDCE6490C916F" modified="2024-05-29" version="1">MAAHLPTINFNPLAPVTPPPEHLSFRKPALPLSAQLKRKAAEANITNDHVTMKKEQSPFNNPSMAPPKPTSIPSANADPNQPPMDPRYVAMVSRIAAYYQQRCQAISNAQQQRCQAWANMHRQKCQEMMQAAMLVVAWYIRDRIQRRRRRQKKQFRTGLRAQSTRSRVTKGEGVRRWVMNVPEGMSSPHIPGLDDLADQEEAHFSMDKEVPPDKDAKLFEMADNMIRSQYRKDGSELVHRGTGTGTGSRGKDSGLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP25</accession>
    <name>A0AAD8XP25_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_725941</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371018.1">
        <property type="nucleotide sequence ID" value="XM_060512747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP25"/>
    <dbReference type="GeneID" id="85396645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000544">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000069">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000236">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="78"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="475"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="584"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1730963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="729" mass="80893" checksum="0487436EAE33AD99" modified="2024-05-29" version="1">MASGFDEEELHISLSPSQIRRRSQQHGAASDAAASAAGRHELQPPVPGAVNIANMGPPVDTTAPLRDKIKTEQRIGAYKIIKTLGEGSFGKVKLAIHNGTGQQVALKIIARKKLISRDMAGRVEREIEYLQLLRHPHIIKLYTVIKTPNEIIMVLEYAGGELFDYIVQNGRMKEPEARRFFQQMLCAVEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVIGGKLYAGPEVDVWSCGVILYVLLVGRLPFDDEHIPSLFAKIARGTYSIPQWMNSGAAGLIKKMLVVNPVQRATIDDIRQDPWFMTDLPPYLAPPVEEFFNTGVDPNKAIQKSDIAPNAPPRVQEKLHNEVTEKISKTMGYGKKDVEEALQAAEPSAIKDAYMIVRENKLMQVNEAMSSLSVDQDGSSSPLPSASSARSGVSTVGGQRPYISKIGILPSSLPNYHKEYMEREKAGPEDHPAPTIVVNEPGSSARTDAEREETARHLKPHSRNSQVRLDDSSKRPQGMTPVVQAKKTKPVRWQFGIRSRNAPWEALLCIHKALNKLGATYVPDEDYEKVHGTEADQPSNDGSFVEEYAPQGANDSTSSIDPLKRYKLPADPWHIKVRWETSKTTALHQASGTPTDGTKTPDSFHVVGDDEGKRDFVALHVDIQIYEMEHGVYLVDFKCSGYETADKRLLEEKDVTSPFPFLDMAARLIMQLAEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP93</accession>
    <name>A0AAD8XP93_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_746804</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370987.1">
        <property type="nucleotide sequence ID" value="XM_060513321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP93"/>
    <dbReference type="GeneID" id="85397219"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042218913" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="12">
        <location>
            <begin position="20"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="13">
        <location>
            <begin position="20"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1730932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="28400" checksum="6F7EB4AAADC2295F" modified="2024-05-29" version="1">MSALKYAFLASAALHTVSAHGTVNGLMADGVFYEGYSPQMQYKKPPPQVIGWSIPKDLSNGFVAVDKYADADIICHVSAEPAPIAAKVTAGSNVTVFWTDWPESHHGPMMDYLAPCNGDCAKVNKADLQFFKIDAVGVVDGAKAPGKWGSDDMLSNNKSWTMTIPANIAPGQYVLRHETIALHEAGREGGAQNYPQCLNIDVQGGGSEKPPGVKATELYKANDEGIKFNIYKDNLDYPIPGPPMMGAEQKPTRRRKRVTVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPJ0</accession>
    <name>A0AAD8XPJ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PALB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_746580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family. PalB/RIM13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371219.1">
        <property type="nucleotide sequence ID" value="XM_060513290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPJ0"/>
    <dbReference type="GeneID" id="85397188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25435">
        <property type="entry name" value="PalB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="109"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="857" mass="95248" checksum="F727E6EFA1CF7FB5" modified="2024-05-29" version="1">MEAKAIREEALVARSTGREALNHAITAADLYMKAAHEAASPADRSRFRRKCAGLISLAEKLKSSPKTAIPSLTQPTVATITSASNPNCHVRHVPSNERTILLRSSRLHGNIFPPWQAEPDVDNFSLSQGQNIFSDPAEYTMSARQESILEAWQRPVDQAREDTIDEDFMASERDCDLVQDVTTDCSVVASLCAAMKILQGGKQSILSSIVYPYNHQKGRPMISKSGKYIFRMHFNGCFRQVVVDDRLPVSRSNRTLFVVDRKNPNLLWPALLEKAYLKVRGGYDFPGSNSGTDLWVITGWIPEQLFLQSEDVDVEGEWDSIKEAYHAGNLIMTLGTGRLTQSEEDALGLVGEHDYAVLEIDSSPGARRLLVKNPWCDGLVWKGVGSSGIVEQTAAVSLSDTLVSIEPRSSEHTRPVGSFWISVEDVAQNFESMYLNWNPDLFTHRQDHHFTWRVPTKNMTSSLAHNPQYSVLSHTEQTVWILLSRHFADEELEIARNKSASLAAVSRQLGFTSIFIFESEGKKVQVREGFVYQGPYVDSPQTLAKFKLRSGTPYTIVMAHQDLPLDQYSCTFTLFSKAPLEIKPAEEAMSYYQELSSAWTRRTAGGNASSITYSQNPQFSISVPRATPLSILLSSGDREVAIHVDLVWAHGRRVTSIGVKDVVASSGDYRRGNALVQVPLVEPGTYTIVCSTWEPGQLADFGMRVGSQVECQIKPVLSDRAGLLRTLAPAFIFNEGEENRRALVTVSRLSRAQVVARCPLQTGRSSQPISTTAVRVSLVYGRGPEELVLAMSGGGEFRELTMAIRTPEFDLEPDRLRQDKLWLIVERLGSQQGRQSIEVEVLSDNPVHVGDWQVTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPV8</accession>
    <name>A0AAD8XPV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_787368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371289.1">
        <property type="nucleotide sequence ID" value="XM_060515664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPV8"/>
    <dbReference type="GeneID" id="85399562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="821" mass="86947" checksum="E908C571F91C1463" modified="2024-05-29" version="1">MTRNTRSSTICEWALGVSVEEYCNSIERRRRKKSSSRQRICVEISTDDESEEDTVKITYPRADRRKDSPGSGSKKVRFEKASKKPALQAVDAEAESKGDTEIQGDKNKSDKADDTSASESEAKAKKKRGVKAAKKKVVDSSSESETDETEDDTPAPSKKKTQEKTKDSVKKSSKTKGSATPADAEPNNVGPTVKKVRKNGGAKTNETKKVDKPQKVMPEAALSPHLRRPNLIMPIRAEVVQVEHTIEGVEDPRPNAFHDPQNGVVRVYHGPAYGNPYGLLYPSRDPNNAPLPMGVPHPLQNPYFYGFANPSNPGDNHFKGQSPWSSMPVTCMPGGPPVMAAVDPMQMGMQMPPWWGPMSPKALSPKGSPKPVMSGAIPGDAASTTGTKNQEQGWDTNVGPQQTKATSPLTKVASPNNVVPASPININLTVNPNTPWAAFASDLSKKSTPNKNGSQNGSKNSWGSKKSTDWQPLASGQHPDLAWGNTATKSQGSNNWSNKGSNKGSNSGWTKIGDANNDSWGATGGSGSNSGWNTTNTAQANDAWGTSGNTQSNDAQTTSGGDGWTATNGTTWDNTDNTDKDGWGTSNDQSADPWANSRGDYSNNWGTGSNHSNSKKSNKSQNDNGSNGGTSGQAKAATDWDGQGNNVGYSESERKVSNNSNKSSKSKKTSPPPPSTNAGWDNNAGPSTNSPVGNSSGKGNGNKKSSKHASKGDTWATASNSAWTTYNNAGPTTNNSPRNSQSSKKSSASKREKTDQWVSAGGGAGWGPETTSGEVNYGPTATEMSKTSSSSKSMPGAWDTNVPPWGDPTLAQSTSGAADQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D029</accession>
    <name>A0AAD9D029_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_748796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369066.1">
        <property type="nucleotide sequence ID" value="XM_060513666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D029"/>
    <dbReference type="GeneID" id="85397564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="114" mass="12658" checksum="1472590C8715B196" modified="2024-05-29" version="1">MSCGHTILSHPTDCDSASCQPQLQPQPAFLNDSCAACHRPASYAQNRARHEAEHAVLMGEYMRADAAGDEDGMRRARRAMLEHTRLLRRRNFAVSLVREEPGGDVEWPGLPACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0A3</accession>
    <name>A0AAD9D0A3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369305.1">
        <property type="nucleotide sequence ID" value="XM_060507350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0A3"/>
    <dbReference type="GeneID" id="85391249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042267724" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11551" checksum="73644BAC8ED5A549" modified="2024-05-29" version="1">MLLLTLLLLLLVVLEQTQIGRAVPVESVMQIVPEAVRPVHAILAGPSTGRRLRCCYCCLLAIALSGVVVTSPNAGEAVGNGRWRHCRRCRGGCRYRCRCKGQICCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0P0</accession>
    <name>A0AAD9D0P0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Guanine nucleotide-exchange factor SEC12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_568083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the WD repeat SEC12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369754.1">
        <property type="nucleotide sequence ID" value="XM_060504023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0P0"/>
    <dbReference type="GeneID" id="85387922"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003400">
        <property type="term" value="P:regulation of COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <keyword evidence="2 10" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="590" mass="63901" checksum="4DEA9CA24CA6341F" modified="2024-05-29" version="1">MASPFETAKLTLDYLPYACEFDPQDPNRLLIGGGGGANRSGVANKITVIDTSAKEELQISGEADLSRNEDSVMTLASGPKKGRTSYLYAGINSSPEEVEKGKNEHFRAFGIEQSKARVSAGANAPSVSLAELSRTSIFAHNEVDKDAYQRVLRLSAPYGEKQLGVVATGLAKQSQIAIFEIAAGNATKPKILGQLDVSKEPVDVDVIQTGEDSYQVAYCDERELFIINVVKSEIDGPHHAYEIKEDGSGTWPNFRSIRYLSKDFVLAGTNIPKRAGAILLGIRLPLKEDEPGRLAATVKLPKAVNQITTIAARNLTPPSAPGAKIGNAQFLVAAVGQDRSISLFTLEHKAHSSIDLLVDFDLLTTLKEVHPLQITNVALSHYVPPKTTARPQYIKLASISMKNTVIVHSILLKKFTDRDAPIRKGGPPRPQRYAVALQPRKWSKTWLAATTVLVLVLAILFQLGLETMGAVQPRILPGGGSVANMPNEFLTSLIGDVHALQGDPIVIREDVVSPTHIEEDPVPRFQAAVHDEEVYGPAVSWEDLAPQQKKLWKEKLSKAGHWTQNMGESVFKGILFGEIAGAVGRAVGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Q3</accession>
    <name>A0AAD9D0Q3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369515.1">
        <property type="nucleotide sequence ID" value="XM_060507322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Q3"/>
    <dbReference type="GeneID" id="85391221"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="277" mass="31152" checksum="06A6F2EBE8C7EC57" modified="2024-05-29" version="1">MSQSIQDIPVGDILPLDHVLQLADRSKLLAARVQEFERNDGLKTPEELRVLTSTMDEVEQTLRPYTMAVLDCILGDIYENILLEQDGTRAGFDEAMTRITRTLRPALLEMDSEPNDSTHTFSLDETPEIVERFQRLILGFEDLDRLVHQPVHNTLVLSEQKVETCVEAGRVKVLMGCVFDAIVSYTRKHLPPRASTHTVVVTVVRCESLRRHEGGGPPLLRRQDATVGQERFEPPSLRRQDATVGQGRVASSGHSSRNIPRLRRRDAIIGQNTEATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1I1</accession>
    <name>A0AAD9D1I1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tim44-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_567321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370114.1">
        <property type="nucleotide sequence ID" value="XM_060503943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1I1"/>
    <dbReference type="GeneID" id="85387842"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024621">
        <property type="entry name" value="Mba1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051975">
        <property type="entry name" value="mtLSU_mL45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28554:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07961">
        <property type="entry name" value="MBA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35793" checksum="76DB9880BD17DDE9" modified="2024-05-29" version="1">MYRSARPLLGLGSAAMRPRQPFTRVLPVAKRIAASPAMTVTARRCYASKFAADMRMSSRQNKKASQADGGYSASEIEKSMTMAHIMLPGTFVTVPFSQLDKSPKALWAYTYARLKQRVLDFFAVFGAKVHSMPNWTTKPRFQLSYTKIVPEAKALHRRLGEALAAGDKDTLREICTPALYQTLSAVISRRKATEKLTWELLRYDGKPRIVSHKIAMMPPLGKAPVIQQVVVAISSSQKLDKIEKSTNKPVKGGLRVQNQTEYFVMTRQFNPKTWAPKKWIAWGNTQATTMEDWKMMQKGIKDMERKDYAKRRGENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2C8</accession>
    <name>A0AAD9D2C8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_726338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370536.1">
        <property type="nucleotide sequence ID" value="XM_060512756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2C8"/>
    <dbReference type="GeneID" id="85396654"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35186:SF4">
        <property type="entry name" value="PRION-INHIBITION AND PROPAGATION HELO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="2">
        <location>
            <begin position="341"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="581" mass="65855" checksum="086EB6DF30EDE2B9" modified="2024-05-29" version="1">MSGIEVAGLALGAMPLAILALSDYKKILAPMKVWRHFELEMDSLIENLQCEYLRLQRFCGNHLESLVSTEQWKLMISDPFGSLWKEEVVQRRIKARLQTAFSRFKLAMKELEKAILYIKENLGLDDQWIRRWTEGSAIERELKRASFVLHKPAYDDAIESLKKNLSTLDSMMRDDVESEPLQQKRYQGRLVGLIRHTSGYVYYALRDSMSCRTGCRHQVHMDLKPDSEDATHDLDDAEMIEKLGFKLAMTYRTDMTETVPEKPDQQTLWEEVVVRASAPQVTSSLEPKSTPPPQPPARPQRKGVSFASLRKPPVAITGAEQPSITTSLTSTMSTLKLSDGAMNLSRQIKVCEELRRSHKEGISGTISHQNAGKSWSFTIYPQKSTGPRHNRSVMSLKEFLENPKHPKMPFMAKLHLAKMISSSFLQLHQTPWLPNTLTSQNVYFITDGSQSFPNFRQAFIKKGLPEKIPQNHSPNLGGSDVINSPLLSLGILLLELSLGSTIGDLRRPDDSSDYFTAERLLQESPVDRMSCGGYMLAASWCVAADWSLPKQDFNDEGFRKDVYEGVIAQLENEFKVKPRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3N9</accession>
    <name>A0AAD9D3N9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sodium/calcium exchanger protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_935</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371751.1">
        <property type="nucleotide sequence ID" value="XM_060516016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3N9"/>
    <dbReference type="GeneID" id="85399914"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF18">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="361"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="103"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="55741" checksum="EA16DEAB3837AE88" modified="2024-05-29" version="1">MCFFLGGLRFREQIYNSTVTQMSACLLSLSVISLVLPTAFHASFQNTFKAEDETLKISRGTSVVLLLVYILYLLFQLKSHAYMYESTPQHIVDAESAPGPAIGFFDSSSSEDSSDSDSDSDGSDSSGGTVRKTMRKVMRAGRRRKSSVVSVNTDGLPRTRNSSIGTAHGSEGSASRPAIPRFNSVGSDEAVEEDRSRKHRKHRRRHHKHQKKSKKSSRNNLVDVEGHEPLTSNTQAGEPRRLDFADQPAGPSEPIDTTQAPKTRPVSGLRGLSIKNFAPAVFTTPDETPSAGPAAPAGPVPRVRFGIRRTNSLPDRLNQYGNVRAPGGVFPAQIPGVATVNSGLSAKDETADNDHLSRTAAVLLLLFSTALVAVCAEFLVDSINEVVKTSPLGEIFIGLIILPIVGNAAEHVTAVTVAMKNKMDLAIGVAVGSSIQIALFITPIVVIIGWAMDRDMSLYFTLFETVCLFVSAFIVNFLVLDGRSNYLEGALLCATYIIIAVVAFFYPNSDEASSFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6T7</accession>
    <name>A0AAD8U6T7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358546.1">
        <property type="nucleotide sequence ID" value="XM_060509557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6T7"/>
    <dbReference type="GeneID" id="85393456"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="27322" checksum="71D13A374CEA834E" modified="2024-05-29" version="1">MEQQVARLVEKAWNKFQETPEEKRLLIGISGIPGSGKTTLSQIVTTHLNARAKTLDPSNPIRTAHSPAAFVPMDGYHLTHVQLSAMPDPQTAHARRGAAFTFDGPAFHKLVTSLREPLRADSSPIYAPSFDHAVKDPKENDIAIQPYHRIVVFEGNYLTLDKPPWSDAAKLMDELWFVDVDFEVARKRLIGRHVKAGIAKNEEEADKRARENDLVNGKEIVDFRLKVDEVVTSREDDEWIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U888</accession>
    <name>A0AAD8U888_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_645506</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000330">
        <property type="protein sequence ID" value="KAK1701893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357075.1">
        <property type="nucleotide sequence ID" value="XM_060509850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U888"/>
    <dbReference type="GeneID" id="85393749"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877:SF2">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1701893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="171" mass="19594" checksum="7345197D5BAF09B6" modified="2024-05-29" version="1">MDIQISPATIDDTPEILELAQKARADMFPHLDEQWRAMKAEQDLATFQKTFFNHPDGAFMVARSENQIIATVGYQHYDYRFPQLTLLPDGVVEVVRLFVVPAWRRGGLASRLVSALEKAAREAGLKQLYLHTHPFLPGAIKFWERQGFVVLSVDQDDAVWQTTHMSRNLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8R2</accession>
    <name>A0AAD8U8R2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000320">
        <property type="protein sequence ID" value="KAK1702149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357097.1">
        <property type="nucleotide sequence ID" value="XM_060509845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8R2"/>
    <dbReference type="GeneID" id="85393744"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041954586" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14001" checksum="B57FD04FEE69C16A" modified="2024-05-29" version="1">MMTLGLSLVTVGFVVRFIGVAAEVALHDDSKGCTFDTFMAISGFVTSSHNRSSVSMSTVSSTETTSRMMSNRNKTLDSLAKVSGETAKGPVECGSCIASPKTSPPFTAPPRTVAHRATGSSLSAARRLMAPLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Y0</accession>
    <name>A0AAD8U8Y0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 46A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_756791</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359671.1">
        <property type="nucleotide sequence ID" value="XM_060514797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Y0"/>
    <dbReference type="GeneID" id="85398695"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="57783" checksum="E84040A3D30D49A9" modified="2024-05-29" version="1">MKTDMARTAGLLGSGLVSAPVTFILLLLLWRAWIIVYRLFFHPLRKYPGPILYAASRLPQLSHFSLGSSHSMGVRLHKKYGPIVRIGPNQLSYIDPRAWKDIQGHRVGGRGGFPKDRALMGHQEHYDILHADDATHTRQRRIFSHAFSEKALREQESLIRGYTDLLVSKLGDKASRRDGQTKDNVITVDIVRMYNFTTFDIMADLTFGEPLGMLQDGDYVPWVSNVFSSVKYMVMGTFLRVYPIFGRLFAPLLSSSLKAGMEKHTKYSNDRVDRRLQYDKDRGDIWSLVQRNADLDNISRGEMYANAQIFMIAGTETTATLLSGLTFLLCRNADKLKILSEEIRSLHLQDLNIINLQRLPYLNACLEEGLRMYPPAPGVVPRVAPQGGSTVCGQFVPEGTATSVAQYAAYTSTYNFTDPLDFVPERWLAEPPEKYANDNKEVVQPFSYGPRNCIGKNLAYHEMRLILATVLWKFNVELADQNSNWIEQKSFGIWEKPPLYIHLHSREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Z9</accession>
    <name>A0AAD8U8Z9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359701.1">
        <property type="nucleotide sequence ID" value="XM_060514801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Z9"/>
    <dbReference type="GeneID" id="85398699"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042057945" evidence="1">
        <location>
            <begin position="26"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="335" mass="37669" checksum="F0A3D4F7F4690700" modified="2024-05-29" version="1">MALAAGSKRMVQMLWLAAGLLFTLALLHSLGSPDKAKEWASNKVGALVNNDGGRNTMKEFMATAESIWAKTVKQRHDMIAEDYGDASLMPLFPATDPAAYGKHPYSVWDFAPASYSCPHEMERVGRMGDGGKWVCGMSRYVNFPRDRECVIYSFGVRDESSFENEMLSRTNCVVWAYDFSVVDFGEQLEPGNRARAHFLQAGISGKTDKTKTPPFYSIADLMKMNGHEYIDILKMDIEFAEFEAMDGFGEDFPIRAGEELPVGQLMIEIHFFNGMTASNFLDWWERLESRGLRPTWTEPNLLAVTLNLGNKDPLLAEYTMINVHDSKNVVFGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U934</accession>
    <name>A0AAD8U934_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Necrosis inducing protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_758936</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000289">
        <property type="protein sequence ID" value="KAK1703164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357244.1">
        <property type="nucleotide sequence ID" value="XM_060515113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U934"/>
    <dbReference type="GeneID" id="85399011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135497" evidence="4">
        <location>
            <begin position="18"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1703164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="304" mass="32823" checksum="FD02FF1A7FB08EBB" modified="2024-05-29" version="1">MLKSLGLLLGCTASTYGSLLPRGGDNANGHQWINHDAVVPFTQNAADGLGGSLELRFNPYLWVSGGCDPYPAVDENGNLGAGLKPTGGGRSGCGAGGSGQVYARRGQSQGRNGIMYSYYTPKVRWADGKNNGHRHYWASVVVWVNRWGCEEEDITGIWPVGVSYTADHLNWGTPSTISEISFRGASVGLDMATHPKMQIHDNVISAFKGADDENIIERTLISWESLPNLAKDALTDVQYEKTQVPFNDANFQAQMDAAYQERFFTGIPKVADCDPVEDRPPKVDTPDDAPVTSTSVPKTEPTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9E7</accession>
    <name>A0AAD8U9E7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_644062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000239">
        <property type="protein sequence ID" value="KAK1705636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357660.1">
        <property type="nucleotide sequence ID" value="XM_060509723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9E7"/>
    <dbReference type="GeneID" id="85393622"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="56" mass="5784" checksum="C0199E09D363EBC5" modified="2024-05-29" version="1">MTTGSGSMPSSLSCTACSFITRLGVALGHELNLSKGAQRLGSVTFPDKCPALEWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9F7</accession>
    <name>A0AAD8U9F7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_643958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000235">
        <property type="protein sequence ID" value="KAK1705925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357704.1">
        <property type="nucleotide sequence ID" value="XM_060509708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9F7"/>
    <dbReference type="GeneID" id="85393607"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="65" mass="7047" checksum="71F411718F09A1BD" modified="2024-05-29" version="1">MCRAEAEVREGKQGDAEARDESMFRDPSRTTMKLVDASADTCSFVLVEDKMVRSILYGEAGGGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T5</accession>
    <name>A0AAD8U9T5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAPE-hydrolyzing phospholipase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_636255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360106.1">
        <property type="nucleotide sequence ID" value="XM_060509244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T5"/>
    <dbReference type="GeneID" id="85393143"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070290">
        <property type="term" value="F:N-acylphosphatidylethanolamine-specific phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070291">
        <property type="term" value="P:N-acylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070292">
        <property type="term" value="P:N-acylphosphatidylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000048">
        <property type="entry name" value="Zn-dependent hydrolase/oxidoreductase family protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="147"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="423" mass="47381" checksum="71025E6DE6E806F7" modified="2024-05-29" version="1">MSKFRQFFRIFFQQPPIRPGTKKASATPASVLALSMASYSTTVTKIPDLGPSPEDASSKPHHVTKNGNRVGFKNVHPSFGDGIGFSKMVRHVLWPQVTGELKWPDTTPPTVTVKKPEFLPNRTASDKLRATWLGHACYYVEFPSGLRVLFDPVFEDRCSPFSFMGPKRFTPKPCDLADIPFVDAVFISHSHYDHLSHESVLTIQKHNPKAHFFVGLGLESWFKNAGLKNVTELDWWEDAEITLNIDKGVDEAPESITAQVSCLPCQHTSARTPFDKDTTLWASWGVKSAGKSVWFGGDTGYRAVPWTPLDVDDYGPKYAHLPMCPQFKQIGEFRGPFDLGLIPIGAYYPRVAFSGMHANPFDSVEIFQDTRCQRAMGIHWGTWALTMEEVLEPPKLLQEAMKKKGLPPTGVFDVCEIGESRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T9</accession>
    <name>A0AAD8U9T9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_644138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000241">
        <property type="protein sequence ID" value="KAK1705480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357636.1">
        <property type="nucleotide sequence ID" value="XM_060509729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T9"/>
    <dbReference type="GeneID" id="85393628"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF315">
        <property type="entry name" value="TRANSPORTER MCH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="240"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1705480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="459" mass="49014" checksum="17B08DAD2282CA42" modified="2024-05-29" version="1">MTTSNEPRRETKSSPPLCQEPPQASIAREVASDGGYGWIVTTSIAIIYAHSWGISAAYSVFLAHYIRSDTFPGTSALVYAAIGSLSIGITLVISPLATIMARELGTRPTMLLGAVLQSASLVCASFASRIWHLFLSQGLLFGVGMGLLFLPSYGIVAQWFTARRALANGVAIAGAGLGGLTYSLAVGAMMNRMGLLWAYRVLAIVSGVANGVSVLLIRTRYGETRAKRLALDTSLFKRVDYLLILGFGALSMLGYFILVFTLANYANVIGLDPSQASQVSAVFMLGQAVGRPVIGWLSDRFGRINITYLMTLVTGILSLVFWVNAKSFAALIAFALIVGLPAGVFWVNAAPVIAEVLGTENLASSLSLLWLMMVVPSTVSSPIALVIYMRTGTYLGAQLFTGFTFVAAAGCVFVLRRHQIRLRRKASGFTLDSFGEDGIGPMGSRMQQGFIGLSSWVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Z0</accession>
    <name>A0AAD8U9Z0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microtubule associated protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_758576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000241">
        <property type="protein sequence ID" value="KAK1705478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357634.1">
        <property type="nucleotide sequence ID" value="XM_060515056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Z0"/>
    <dbReference type="GeneID" id="85398954"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990023">
        <property type="term" value="C:mitotic spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051256">
        <property type="term" value="P:mitotic spindle midzone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007145">
        <property type="entry name" value="MAP65_Ase1_PRC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321:SF41">
        <property type="entry name" value="FASCETTO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19321">
        <property type="entry name" value="PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="661"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="511"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="664"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="719"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1705478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="816" mass="92200" checksum="D8D01FC02E585432" modified="2024-05-29" version="1">MDTSYLSQQVNTIIGQLHGLFDEIGVPNHDREKREEDLFEALSKALTDQVNLVTNEKEEMIEEAERIITTIQQMEASLDDNRARRDRSDEIQITYPLTRCLQGLKEKHKQVSRLHKERFEQVKKLVEALESYSSHLEPTFVKIPLPPTGPNQSVPPNFDLSPSYVDKLDHEFTRVYEEYTRRVATVKALCEHTIQLWAELGTPQAQTDGAIVKYYRESPEQLGLHEEDIERLKAKRDKLSDEKKNREKRLKDLRAAVEALWEKLEVDMAERKAFLNSNRGCGVRQINEFEDELVRLNELKRQNLHLFVEDARFKLQELWDSLYLSEDEMLEFTPAFSDVYSDALLEAHEREIARLEVLKEQRLPTLELVERHRSLTSERDELAASSQDASRLMMRGQKGEKRDPGKLLREEKMRKRIAKELPKIAVDLRRILERFEDEYGRPFTVHGERYLDVLEAEDRPAPGPRSKTPGVGAAPQSAARPRGHSRAQSTTSIARPPTRNGVRTPAPAPTTKRSANNMNSAAPSTRPVSAHAKAQEIARPASSMGSLRERAQTLNRPPGSPSRIPARPPLTNLKYGNFGNTSPVQPERPASRIDAYATIRGGNHQMRAPPPKMRDLSTIELETPVNPYKSVGLGASIVRQVELEDPYDEDCQQPRLMRANSTLSHTSHASHNSHASYASQSSHHSQGSSQHDYPSSHSSTIRQYPPSSYPQAPPPRQISNSSNGSSNVTGSENWETYDDASEPEQDASDTYYAKVRAARNGTKRFEPEAGYRPPASDPKRQRPFPMTAPGGHAGHGYGDGEGRIISGSEWTDEDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAD6</accession>
    <name>A0AAD8UAD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Sec23/Sec24 trunk domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_757355</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359038.1">
        <property type="nucleotide sequence ID" value="XM_060514887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAD6"/>
    <dbReference type="GeneID" id="85398785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="12">
        <location>
            <begin position="299"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="13">
        <location>
            <begin position="377"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="15">
        <location>
            <begin position="630"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="14">
        <location>
            <begin position="726"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="11">
        <location>
            <begin position="856"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1711235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1016" mass="111173" checksum="003D71382D3B79BC" modified="2024-05-29" version="1">MSDFSMYHQLGQGEQDPSNPNRSTQPAPPQFSPPVAGQQYQQGTPYGAPAPPGQQYYGGQPGSAPTQAQPYGAPPGQEYAQSPGFQSQENLAAQMGGMSLGDGHGTARRKKKDRHAYHQVEATGSSQPFNGIPAAGTNATAFLNDPSQAQYAQMNQFPVAAGQTFTPANPASPAEFATRNGADAGGPPAVVQTSGHQKLSLDDLPSVPVSRDSLQQHYFSNVYPTFEKHLPPPSTVSYVAYDQGNASPKFARLTLNSIPSNAEGLALTGLPMGLLLQPMAPLQPGELEIPVLDFGDSGPPRCRRCRAYVNPFMMFRSGGNKFVCNLCTYPNDTPSEYFSALTPQGVRVDRDQRPELTRGTVEFVVPKEYWTKEPTGLRWLFVIDVTQESFNKGFIESFCEGIVAALYGGEDAERDENGEPKKSIPPGAKVGFVTYDKDIHFYNVNPALDQAQMMIMPDLEDPFVPLSDGLFVDPYESKDVITSLLTMLPTMFSNIKNPEPALLATLNSAVAALEKTGGKIVCSLAALPTWGPGRLFLRDDGKHPGGEIDKKLFSTEHPAWKKVAEKMVATGIGADFFLASPSGGYLDIATVGHVAASTGGETFYYPNFIGARDNTKLSMEIKHAVTRETGFQALMKVRCSNGLQINGYHGNFIHHTFGADLEIGVIDADKAMGVTFSYDGKLDSKLDAHFQSALLYTTASGQRRVRCSNIIASVCDNPRDSVKFIDQDAVFTILAKEASTKLASTSATLKDVRNHLTERTIDILSAYRKNFLTSAQPDGQLVMPERLKEFSMYMLGLLKCRAFKGGNESSDRRVHEMRMIRSMGAKELSLYLYPRMIPIHNLTPEEGFPDESGHLKVPPAIRTSFSRVEPGGVYLVDNGQQCLLWLHSQTSPNLIADLFGEDKTTLQSLDAYTSSLPMLQTHLNAQVRNIVEFLKTMRGSKGLGIQLARQGIDGAEYEFARMLVEDRNNEAQSYVDWLVHLHRSVQLELSGQRKRDDPLTDANALAGFAGLRPNYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBV8</accession>
    <name>A0AAD8UBV8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA ligase</fullName>
            <ecNumber evidence="7">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_680694</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360182.1">
        <property type="nucleotide sequence ID" value="XM_060511204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBV8"/>
    <dbReference type="GeneID" id="85395103"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3260.10:FF:000004">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000018">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF9">
        <property type="entry name" value="DNA LIGASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="10">
        <location>
            <begin position="544"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="639"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="853"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="853"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1715039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="873" mass="97198" checksum="83C6D6814F5ED982" modified="2024-05-29" version="1">MPSPSKKRKLNDQSSTGVPSRGLEYFFSKQKQNGTSSPKPTTEPAPEAIPNGTGSADQQPELTDEELARKLQAEWDAEVQNERAESTPCPEPAKDPSPRLNETNGEEATGTKPGPHRSLTSSVLPIVTPKTKTLSLSSVANAEDTVSATIPLDQSPLTFDPSEYVPQLKESWAAEGGHASYAFLTRCFILVSATQSRIKIVDTLVNCIRVLIEADPESLLPAVWLATNSISPPYISLELGLGGSAISKALKQVCGLDGRSLKTLYDKHGDAGDVAFEAKKKQSFTLRKPKPLTIKAVYQSLVKIANSQGQGSGEAKQRIVDRLLQDARGGEESRFIVRTLCQHLRIGAVKTTMLIALSRAFLLSRPPGAEFPLRSVKDLQKLKKEELAEVWSRPEEVLKACFARRPNYNDLVPVLLEIGVCDELLLRCDLTLHIPLRPMLGSITRDLSEMLTKLQGRDFACEFKYDGQRAQIHCDESGKISIFSRHLELMTDKYPDLVALMPKVRGEGVNSFIMEGEVVAVDSETGDLKNFQTLSNRARKDVAIGSVQVNVCMFAFDLMFLNGQPLLNRPFRERRELLRSMFIEVPRQFTWVKSLDATSQDSDAVLDFFKAATDIKCEGIMVKILDNLTDVPYQGDGAVDADGEVAEEPRTPSKSKSRSKGTKDEEGAPKKKGRRKPLLATYEPDKRLDSWLKVKKDYNASFETLDMIPVAAWHGQGRKSKWWSPILMAVRNEDSGALEVVCKCMSGFTDAFYKANREHYDDGELAERQNTRTRKPAFVEYSGPEPDVWFEPQEVWEMAFADITLSPTYTAAIGLVSDERGLSLRFPRFLKKREDKSMDEASTNEFLAGLWRKQEAKAPTKEGQADVMDEFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBX9</accession>
    <name>A0AAD8UBX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit B</shortName>
            <ecNumber evidence="7">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_657237</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000179">
        <property type="protein sequence ID" value="KAK1709728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358639.1">
        <property type="nucleotide sequence ID" value="XM_060510948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBX9"/>
    <dbReference type="GeneID" id="85394847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295878" description="Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial" evidence="9">
        <location>
            <begin position="19"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Asn/Gln amidotransferase" evidence="10">
        <location>
            <begin position="579"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1709728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="771" mass="85896" checksum="4C2CCC2D9A80B073" modified="2024-05-29" version="1">MAALLACVALTPLISSACAPFLPCLRGCNACTIMSAPEPENLALPLRDGSEEARKPLRPEKMAIPKINLEDTYNPTTNQATRYPNKRVYNIQAKQTGLYDSNRFESSTDQFKESAKLAAPDPARKRLSLPPIIPRAKSSLPEMARIPTRELARYLFNGQLSRQGCLSSTRRPYIRLPARSALAQPSAPQFGESRATYATAQTAAAASQEPPPVPLRKKLKEEKKQLKKETRGQKPKGSTQTVEGWELTVGIEIHAQLNTARKLFSPAATSFNDDPNSHVALFDVAMPGSQPRFQEETLIPALRAACALNCDIQPVSRFDRKHYFWWDQPSGYQITQYYEPFARNGEIELTARDGIAAEDGESVTIGIQQIQMEQDTAKTLAQPNDVSWLDFNRVGMPLIEIITKPELHYPRTAAVFVRKIQMLLNAVDACVSGMETGGLRADVNVSVRRTGDPNTPLGTRTEIKNLSTIKAVEDAIIAERDRQIKALDAGETIASETRGWTLGSKHTRRLRGKEGEVDYRYMPDPDLGPLVIGQDLVDHIRASVKELPDIELTELIEKYGLTAKDAVSLMSLDDGGRLEFFYKVVDELRGQLESAGLETNLHDYASLAGNWILHELGRLTTDKADPDAAQRTLAISPDGSCEAVPHSALAGILFHLQKRDITGKVAKELLVAQYLSNLDEFDSVTDAIKTHELWFKEMTEAEYRQLAEEVVEGEDKVLREFMDKKKKYPQGKLMYLVGKMMRIGETERIDPSGAEKVMRQLIKERTDAHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC30</accession>
    <name>A0AAD8UC30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_640469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358836.1">
        <property type="nucleotide sequence ID" value="XM_060509490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC30"/>
    <dbReference type="GeneID" id="85393389"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000002">
        <property type="entry name" value="putative tyrosine-protein phosphatase auxilin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000354">
        <property type="entry name" value="UBA domain-containing protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="276"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="764"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="903" mass="96140" checksum="EF036129C0CDC1CD" modified="2024-05-29" version="1">MDDLSGLNWSSSTNKTNNKPPPMNPSGANYFGSTRPTNSTPSPFPSGRNTPLSAQGSGAVAAKPPPAKPPADSFSNLMNFGGAGAAKPTSKLTLLEQQQRLEAEKRKKEEERRKQAQAQFGGGFLDTLGSGSVSRTTSPGILSPGSSTGKKASDDDDLFAAFNSETKVDNASHYPPPPQKSPSPAIAPGLDLSNPSAWNQAPPPANGGFGDDDDPFGLNQLKPKAASPAPPPTNDDDDDFLGDLGRPVEEIRRKQPTPQPKGPEPGKPIEASDSSSEDERQQAPRGEMAEFDSAVAQLVDYGFTPENARRGLTESGAGLNVQAAANWLLDDAHRQAKAKAQGKDPEAASRRGRDDGGRQDSQRRADTRSPAGEADFSKTAAAMGNSLFKTANSLWKTSKKQVAAAVADFNQPEGDPSQPKWMRSAQADRAQPERRVAEATDEAMMLESGGRPQRKAGQSSQSSRPEAPRRTASPRDQSPTVSAPSSGRGTPVPRWQQQSGPAVPDSRTRASKLAMADDSAASYVSPARRKKATAQPEAPPPQREEPDLLFGSQAPKPSQSLPQRPAQPSQPSRPTQPAQASRPARPPSPKPAPRPARQIPPITPAAVQQSTKHRLDGTAHFKRGDYGAAHSSYTSSLSAVPSSHPLAIVILTNRALTSLKNGEPKRAVEDADAALKIIGPGGGQGEQVSVVGDTGGQENRDMRDLYGKALSRKAEALEQMERWGDAHAVWSACVKNGVGGPTAISGRQRCQSALAPKPKPKPRPAAATPARSRPVAASAKNMEAVERLRKQNQAAAQEDDEKFALSEKVDAKIAAWRDGKRDNLRALIGSLDSVLWENSGWKKVGLHELVMANKVKIHYMKAIAKCHPDKLPQDASTEVRLIAATVFATLNESWDKFKSENGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCS2</accession>
    <name>A0AAD8UCS2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_756154</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360463.1">
        <property type="nucleotide sequence ID" value="XM_060514707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCS2"/>
    <dbReference type="GeneID" id="85398605"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="466"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="57513" checksum="BA1D082989BB818A" modified="2024-05-29" version="1">MGSFTQKVKGNKIGAVILSVFDWYPSHYPAEERKLLRKLDLAILVFGSLSFFCRFLGQQNVTNAYVSGMREDLDSHGNELNYYVVAYNTAYVIGQIPLMTLQTKAKIAPFLLPSLQIIWAVIAFSQSTIKHSWHLYILRAITGFLEASSFGGTHLILGSWFKNEELFKRAGVWFMGNSLGSMFSGYLQAAAYRNLNGVFGRAGWRWLFIVQGIITLPISFLGFAFWPGLPTSPKRWYFSAEEHALAVKRMPTVEQEGITWKTFKYTLSRPMWWICVPCYIFLCQAHYWTGYMALWLKAAGYSVELVNILPTFIDLLRALSSWLGTTLAGCLSLRGLWSFQASFVLFSCIVLSIWNVPDILKFLAFYFGGFSGMASPILYSWLNSTLKENYGERGLIISSMMTLGFCGQIWIPLFTFPTVEAPRYPHGYPAATVFEVAMWAFLMFGTWYMKRWKHKHPDLEMRLATEEAAAEGSSGIGSDSDRPDGDSPAPQYTGKGEEIVATQPVSQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD03</accession>
    <name>A0AAD8UD03_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_41443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360598.1">
        <property type="nucleotide sequence ID" value="XM_060502936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD03"/>
    <dbReference type="GeneID" id="85386835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="98"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="26783" checksum="06ADAC4EFE9043C6" modified="2024-05-29" version="1">MSRAKVELIPWDPISPDHVTRMIDQRIACGWASDLVPQWQENQQTGFKCIYWIVFADDDTEREARLAKHIAEYPKEKVFILDTADSISATPRTPTGASFHPVGHISLDIDNPAAAPLNLPIPKENVYWIKSLYVSFALQSCGIARAAMDMVESMAISEPLCAKTLMLDTVSKEDQLRKESMVVAQGKLPPTPTHAWYERRGYKLIHTINNFYGFPEKDPDGNLLIRRTVFLRRDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEL3</accession>
    <name>A0AAD8UEL3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">linoleate 8R-lipoxygenase</fullName>
            <ecNumber evidence="3">1.13.11.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_755114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate</text>
            <dbReference type="Rhea" id="RHEA:25395"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:58659"/>
            <dbReference type="EC" id="1.13.11.60"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.60" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361562.1">
        <property type="nucleotide sequence ID" value="XM_060514569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEL3"/>
    <dbReference type="GeneID" id="85398467"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052878">
        <property type="term" value="F:linoleate 8R-lipoxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF13">
        <property type="entry name" value="LINOLEATE 10R-LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1719478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1172" mass="130670" checksum="7C0826AE9A422B45" modified="2024-05-29" version="1">MTTNFTQKFQAGESYGDARQDSANFFNDPAKIAADILKDYVSVRGQTSPAELVGLIKELLSKGEPLDDKKGTTEILIGILTSLPATSKARTMLTNKLIDTLWGNLQHPPLSYVGGDIKYDALNEEGVVLDSNGQPQTKEPQATDSIEFTAPGTNIRLREQVPQAPDGLHHYRSPDGSFNNILEPNLGKAGTPYAKSVRTSKRLHGVKPDPGLLFDLLMARDEGSFKENPAGISSMLFYHASIIIHDIFRTNRTDMNKSDTSSYLDLAPLYGSSLKDQLEIRTMKEGKLKPDTFHEKRLLGQPAGVNVMLVMYSRFHNYVADILLKINENGRFTLQTKPNATDIEKAKAVAKQDHDLFNVARLIVGGLYINISLHDYLRAITNTHHSKSDWTLDPRVEINKQFDSDGVPRGVGNQVSVEFNLLYRFHSCISKKDEKWIDGFFGKIFKGKQPADLQNISIEELGKAFVDYEQSIPKDPSVRTFDDLKRQEDGTFKDEDLARILKEAMNDPAGCFGARMVPKALKIIEVLGINQARRWQVASLNEFREFFGLKKYDKFTDINSNPDIASLLEKLYTDPDMVELYPGLMIEDIKPVRNTGSGICPTYSVGRAVLSDAVTLVRSDRFNTIDYTVSNLTAWGFNEVQQDYKTLGGSMLYKLIQRGLPNWFPYNSVAVMQPMYTKKMNETIAKEIGTFHLYTLEDPTPPRKAIITQTSGAIKYVLSNPKQFVLPWLRPLQAMFTDSKRDISWFMLAGDEQKNYQHRINIKKALSKIPTLHNAIHEFIDRVGAELVKKETFKMKEGLHQMDIIRDVAIPLNAQLLADLFYFDLRTDENPGGTLGHAELYNHLLNVRIWGVNDNDPAQSWNRRRRAIESVNVIIESTAGPVKEVHAGRGLGFGIANAISSAVGRRANFKKDSLRSCGYKFVEELLAQGNSVDQVVDNMWLTAFGGIGVPVTTFYEVLSFFLRPENASIWAEVQNLAQNKDDAGLHAYVREAQRLTSGQRNVCVATAPAEIDGKPVQPGTAVVMLLGGAGRNPGEIANPDKFDANRKAEEVSAFSYGQHECLAKDIATTFVVGLVKLAADLKQLRPAPGQMGIVKTIQVGSEKAYLNDSWSYLGFDASTWKVHFDGHGKGTYKGDAAAPNNQIDLGQYYYLLKQRKENLLSSLGGPATIRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF22</accession>
    <name>A0AAD8UF22_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_638143</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359555.1">
        <property type="nucleotide sequence ID" value="XM_060509350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF22"/>
    <dbReference type="GeneID" id="85393249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="192" mass="21443" checksum="2112F89B4A726B17" modified="2024-05-29" version="1">MLPPKRFPFPLQLGTDLCQISRIYRILASDKESRFLRRILTKDERLAIPADLKSADASATPSEYSKDDDFQTLKKRNPLLWKNASFLAGRFAAKEATFKAHPTRNLTWHDITIVRKRFEQLKNIGELNEAKEPKKLEAKETEPPSANGSGPPVAIVRSIHEGTPGQEVLLSISHDGDYATAVCLAFEAQSDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFP6</accession>
    <name>A0AAD8UFP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenazine biosynthesis-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_391328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363417.1">
        <property type="nucleotide sequence ID" value="XM_060502789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFP6"/>
    <dbReference type="GeneID" id="85386688"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF32">
        <property type="entry name" value="ANTISENSE-ENHANCING SEQUENCE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="33549" checksum="0BCA0C6884FB7094" modified="2024-05-29" version="1">MELPYTTVDVFTDKPFEGNPLAIVTIPASTDLTQEQKQAIAREFNYSETTFVHEVDDPASTERRFDIFTPTAELPFAGHPTVGTAIFLKSRGVKKLIAKAGPIEIEETGAESVRAAIPHNTHLHQKRLKDLGPGPYSNATAELAAAEAEAPVFSIVNGMTFALIELPSLASLAWAKIGPMEFRQQELLDEGWRKTFISRYYFVRLGAETIDGRVVHKIRTRLIEPDLEDPATGSAACALSSYLSLHELSEDSLSFEITQGVEMGRKSNIYVDAKLGRGENGARKLETLHLGGKATKVMSGTIFLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFS3</accession>
    <name>A0AAD8UFS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_655383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360768.1">
        <property type="nucleotide sequence ID" value="XM_060510795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFS3"/>
    <dbReference type="GeneID" id="85394694"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="243" mass="28381" checksum="8B861BFE5F920467" modified="2024-05-29" version="1">MLSSLPSLKHLALRDCIRLEGDSFPHLPSLVEAHFYHCELPENEIFERRPSLKVLVIDNDYCLEDEDTEVCDVNPLADTVETCGWLVEEPAPFYYPLRQFRRVKHLKVDLIHDLFGALPYEIIPSYDGLPNLAATVETIEFTSRITSRVTGGDPNAHALYYRNWQKSMEELRYTINMMEECCRKEWRKVRLIDISMLALSYRRERSGYDVRPTRDSIKAEGLQLLECAKRRFQQELGIELLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH17</accession>
    <name>A0AAD8UH17_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">BDZ83DRAFT_581756</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="28">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 22">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1723018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363073.1">
        <property type="nucleotide sequence ID" value="XM_060505485.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389384"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2490:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 24" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 24" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 22 25" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="26">
        <location>
            <begin position="141"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="27">
        <location>
            <begin position="1088"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="23">
        <location>
            <position position="1271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1742"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1743"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1744"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1842"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1843"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="25">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="KAK1723018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1856" mass="203620" checksum="04E4D1405FC2FEEF" modified="2024-05-29" version="1">MRPEVEQELAHTLLVELLAYQFASPVRWIETQDVFLAEKTAERVVEIGPADTLGVMAKRTLASKYEAYDAAKSVQRQILCYNKDAKEIYYEADPIEEEPEPAAASSSAPAAASSSAPAAAAAPAAAAPPPPSAGPAAQVADAPVQAIDILRALIAQKLKKPLAEVPLSKAIKDLVGGKSTLQNEILGDLGKEFGSTPEKPEDVPLDELGSSMQATFDGQLGKQSQALIARLISSKMPGGFNITAARKYLETRWGLASGRQDGTLLLALTMEPPARLGSEADAKAFLDDVTQKYAVTAGISLSTPQAGAAAGGSGGGMMMDPAAIDALTKDQRALFKQQLELLARYLKLDLRAGDKAYLNSQESEKVLQSQLDLWTAEHGDFYAAGIQPVFSSLKARSYDSSWNWARQDALHMYYDIIFGRLKAVDREIVSQCIRIMNRSNPTLVEFMQYHIDNCPAERGETYKLAKELGEQLIENCKEVLNANPVYKDVAVPTGPQTTVDARGNLNYEEVPRASCRKLEHYVQQMAEGGKISEYGNRTKVQNDLRRIYKLIKEQHKMSKTSQLEIKNLYGDVLRSLAMNENQIIPNEDSPSKKAKPGKVETIPFLHLKRKSLHGWDYSKKLTGYYLQSLEEAAKDGVTFAGKHALMTGAGAGSIGAEVLQGLISGGAKVVVTTSRFSREVTEYYQSMYTRFGARGSQLVVVPFNQGSKQDCEALIDYIYDPKNGLGWDLDFIVPFAAIPENGRQIDQIDSRSELAHRIMLTNLLRILGSVKTQKAERGFETRPAQVVLPLSPNHGTFGNDGLYSESKLALETLFNRWHSEDWGQYLTICGAVIGWTRGTGLMSGNNVVAEGVEAFGVRTFSQQEMAFNLLGLMSPAVVDLCQSEPVFADLNGGLQFIPDLNQTMTKLRKDIMETSEVRRAVTKETAIENKVVNGPNSEALYKKTLVEPRANLKFDFPTLPDWEEEIAPLNDRLKGMVDLEKVVVVTGFAEVGPWGNSRTRWEMEAHGEFSLEGCVEMAWIMGLIKNHNGPIKGKPAPYSGWVDAKTGEPVDDKDIKQKYEKYILEHSGIRLIEPELFGGYDPEQKQLLHEVVIEEDLEPFEASKETAEEFKREHGDKVEIFEIPESGEYIVRMKKGAALLIPKALRFDRLVAGQIPTGWDAKRYGVPEDIVSQVDPVTLFVLVSVAETLLSAGITDPYEFYKYVHVSEVGNCIGSGMGGAGALRGMHRDRYLDKPVQNDILQESFINTMAAWVNMLLISSSGPIKTPVGACATAVESVDIGYETIMEGKARIVFVGGFDDFGEEGSYEFANMKATSNAVDELAHGRTPAEMSRPTTTTRNGFMESQGCGVQLIMTAKLALDMGMPIHGILALTTTATDKIGRSVPAPGQGVLTTAREHAGKFPSPLLDINYRRRQIELRKKQIKQWQESELEYLYDEVEAIKAQGQEVNEKEYAHDRAEHIKREAERQEKDVLRSLGNNFWKNNPEIAPLRGALATWGLTIDDLEVASFHGTSTKANDKNESSVICQQLRHLGRKKGNAVMGIFQKYLTGHPKGAAGAWMMNGCLQVLNTGLVPGNRNADNVDPIMEQFDMIVYPSRTIQTDGIKAFSVTSFGFGQKGAQAIGVHPKYLFATLDEKTYEEYSAKVNARQKKAYSFFHKGLVNNTLFVPKSNAPYTDEQLSKVLLNPDARVTEDKKTSTISYPSNFMKASEKTVTSTAAKATQDMMEGLAKKVANKNSNVGVDVEDISAINIENETFIERNFTAGEIKYCQSAPSPQSSFAGRWSAKEAVFKSLGVSSKGAGAPLKDIEIAKDESGAPTVKLHGEAAAAAKKVGLSDISVSISHSETQAIAVAVANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHB1</accession>
    <name>A0AAD8UHB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_755971</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360680.1">
        <property type="nucleotide sequence ID" value="XM_060514687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHB1"/>
    <dbReference type="GeneID" id="85398585"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="290" mass="30002" checksum="2439F25C69E6DE12" modified="2024-05-29" version="1">MSDRVAQIASHLNYPKGMLAGQVAIITGSGQGIGAEAARLFANEGAKVVVSDIDGKKAQQVADSITAAGGQAISVPGDMLSADYITTLVAEAAEFGGGKIHHIVNNAGYTWDGVIHKMTDKQWDTIIALHSTAPFRLVRAAAPYFRVKDGENRCVVNISSTSGVHGNAGQANYAMAKAGVTGLTKTIAKEWGPAFGVRANTVAFGFIKTRLTDAKEKGAFITGPDGEKIALGIPQAQKAAGAAEQDAHADIPLRRPGSPTEAASAVLAVVSPLFSYVSGQTIMVTGGRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHI5</accession>
    <name>A0AAD8UHI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cutinase transcription factor 1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_584845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361713.1">
        <property type="nucleotide sequence ID" value="XM_060505802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHI5"/>
    <dbReference type="GeneID" id="85389701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="702" mass="78663" checksum="CEBAB03375F607EC" modified="2024-05-29" version="1">MTNLRRRARQACRACNARRVKCNVTEQRPCRNCTTADTPCELRESRRGKHPRPSRRSAKPGDQGGLDQAGSSPSFIDTSLLDESLATGNDEHFAASQALADLARYREAEGSGDQESITVQPQSPSLAPNNRQEDDSSVFLGESSSIRYVTNSNPTPPTAGTSPPENLKFLHAVPHAVRAENLLPEWEVERRKSRIRSLKAEGVFSFPPVPAVETLLKTYFKWFHPCFPVVDETDVWTSFRDGTLSPLLLHAILFIAVIHCKEDDLPAIGLGGRHVAKWVFYNRAKDIYDVEFEPKKFTVTQALFLMSFWRAGLLLEKDARHWLGAAISLAQTKALHRSSRSAVIEKRTERLSRRLWWAIYIRERQCAAALGLPNRIRDEDCDIEPLEELDFERAFDPILPSPKAQEYISYFISIAQLSRVLGRIVHSGYLPSKSLSPSDRSQMRDDLVKWRKQLPAVMSLANNDFGDAAGFHASMLHLAYNNLLILLYRSGCIGSAEESKEVDGQIALQAAARNSRIIEDMLLEGNLRHGQIHVITNLFNTLCIHTVHLRSLNGTGRSIIEHRAKICLLGLQELQKTWEVRMWVLQLFFQYLDRSTAARLRMQDDLSFAYGLDGVQDVNAGPVVMSGLNHGPAEHDGEDGLDTLLASEPPWSWSTEEANQFLFTQIENDFAFGEGGILNWNTGTPATDSPSIDSNSQTTVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHJ7</accession>
    <name>A0AAD8UHJ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aflatoxin regulatory protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_755057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361728.1">
        <property type="nucleotide sequence ID" value="XM_060514563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHJ7"/>
    <dbReference type="GeneID" id="85398461"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42044" checksum="3C2C6CF0CD9BF6FF" modified="2024-05-29" version="1">MDFLPCTPSPSDASFGSISGSSISSRIGSIDCMADTSVTDFSDSRTSTPSTGENMEAKLLDYFDGVPSNWDNRPGCLPAPQDLDWLLPYSINITNPLCDTNFPIEDLLALDMPSPTFTSSCFSMEQSSPSQSMQQYMGISTPDSLPDFGMSYPNHTPGTEQTKLNPVSTPDVSQGSEIHQRLPIPMSVPEHTSHSTSTKDCNCFSLICQLQESVYHHTQLSSEIDSQVPLGILLDIESSIHHTEETIRHCQDCKPRSSHFMMMLCPVIDWVVDSLGKVLLRGVAPGSASPPHEQPTKSVPQVGELGISDGNGGIPNLCIYELLKGRLRRLGRILNGMGGETQKGSVEEPAYLDSKCLVKAMGTMEQDIRTKLEYHLRLVELWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP2</accession>
    <name>A0AAD8UHP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diaminopropionate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_626485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363418.1">
        <property type="nucleotide sequence ID" value="XM_060508565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHP2"/>
    <dbReference type="GeneID" id="85392464"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006058">
        <property type="entry name" value="PRK08206.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42937">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42937:SF1">
        <property type="entry name" value="DIAMINOPROPIONATE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="3">
        <location>
            <begin position="35"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="550"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="757" mass="80351" checksum="1A4C4FFD7E225FAD" modified="2024-05-29" version="1">MTTTRRNVYINHKTGPIKPVSDASLAQAFHQQLPAFARTPLVSLEEIAQELGVKAVYIKDESNRLGLPSFKILGASWGTYRAITTELHLPADTPLNEVAKAAQTNNLSLYAATEGNHGRAVAAMAKILGIPAHIYVPSSVDNEAVTNIASEGAKVIVSNSHYDDAVLEAWQASKSVKGGLLIQDNAFAGYEQIPAWIVEGYSTLVREAEQQVADHGLTPSLMVTPVGVGSLAHAVVSHCKSDGRDCAVLSVEPDTAPCLWTSLTAGKPVTVHTSRTIMEGLNCGTVSLTAFDDLRAGIDASATVSDFEAHEAVKYLQTKGVKSGPCGGATIAALRRLAQVSPRSDCLSKDAVVVLLNTEGPRNYKIPLDVSTDDPVTLTQILTSIDSSNPDLSKASGAGEGEIAHYISAWLQHRNFEAHWLEERQGRPSVVGVLRGTGGGKSIMLNGHVDTVSLSSYSPDLDPLSGELKGEGGGRIYGRGSADMKAGLAAAMASMARCSSTSHSPLRGDVILAAVADEENFSIGTEEVIRAGWRADAAIIPEPTNQEMAIAHKGFIWVEIDILGVAAHGSRPEDGVDAILLAGAVQTALLEYSKALPSDSRLGKASLHAGLIQGGEEPSSYPERCTLTVEFRTIPAQTTQSILEDIEHILSSIAESNQDFKYAAPRMTFSRPPLGQSPDDEFIKTFVSATSKCLGEAQEPVACSFWCDAALLNEVGISSVVYGPKSFGIHGKEEWVSVASIREVTSVMETAIQDFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI70</accession>
    <name>A0AAD8UI70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_754910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361789.1">
        <property type="nucleotide sequence ID" value="XM_060514547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI70"/>
    <dbReference type="GeneID" id="85398445"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="466" mass="51256" checksum="416D49206E8AEBD2" modified="2024-05-29" version="1">MGSLAVVDDLVPAENSLFYQSVYPSSAPTVESADGLYFTLKNGQRILDSTGGAAVSAIGHGNERVKSAIIKQLNKFTYAHPGYFQNDPSHELADILVKSTNGQMSRACLLGSGSEAVEGAMKLARQYFLEKDPKAPRTKFIARESSWHGCTLGTLAVGDLKARKEPFMDVLADNVSHVSPCHLYRELESGESVEEYVERLALELEGEFQRLGPDNVCAFIIEPMVGTALGCVTALPGYLQAMKDVCHRHGALIIFDEVMCGLGRTGYMHAWQHDNVVPDIQAVGKGLAAGYGTISAILIHERVIEGLKQGSASFQHGQTYQCHPLNVVAAVEVQRIIKEKHLVRNARLMGILFGHLLRQAFKNHPYVGDVRGRGMFWCIEFVADKTTKAPLDPSLNLARRMRLRGLEKGYDVCLFSSTGCADGWNGDHFLLAPPFTVTPTDVEEIVYRAKRVVDSVFDEMREKGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI77</accession>
    <name>A0AAD8UI77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_742169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363347.1">
        <property type="nucleotide sequence ID" value="XM_060513103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI77"/>
    <dbReference type="GeneID" id="85397001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="40721" checksum="B88A02BC676A2249" modified="2024-05-29" version="1">MCATDNAASSPPRAVGEVQGNIAVEDRDVITVEEQSVASSSTSLSSSILDYRLENGRTYHKYKDGKYYVPNDERENDRLGTRQARNLDLQHNLFIRTFGNRLGTAPPNEPGSKVGRVLDVGTGTGIWAIDFGDEHPEAEVLGIDLSPAQPEFVPPNVRFEIDDLEEPWTYSRPFDYIHSRMITSCVKDWKAYFQQSFDHLNPGGYLEIHEIDVEPNSDDGTLKSDSALMKSLRLWQEAAAIFERPFEDIQSLAGIMADVGFEDVHLERYKWPTNTWPKDRNYKELGAWTYENLAVNWEGFIMAPLTRAHNWTKEEVMLLAMEARKDLSDRSIHAYFTIWAIHGRKPFKTKPTEEATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIG9</accession>
    <name>A0AAD8UIG9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_652774</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363883.1">
        <property type="nucleotide sequence ID" value="XM_060510552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIG9"/>
    <dbReference type="GeneID" id="85394451"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000016">
        <property type="entry name" value="Protein arginine methyltransferase RmtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000034">
        <property type="entry name" value="Protein arginine N-methyltransferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049482">
        <property type="entry name" value="ANM3-like_C2H2_Zf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF116">
        <property type="entry name" value="PROTEIN METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21137">
        <property type="entry name" value="ANM3_C2H2_Zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 21" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase 3-like C2H2 zinc finger" evidence="19">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="18">
        <location>
            <begin position="243"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="20">
        <location>
            <begin position="347"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1723828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="61525" checksum="9D6D62D7ABDC7527" modified="2024-05-29" version="1">MTQDDLKNGARAGSDVSSDESDWDDAEPEEEEAQSFISLLDDTVFPDVDAMLCHCRTKHNFDFLAIRRRLGLDFFGTVKLVNFIRQRIHDGAGLPETISVDDIADERYMKPVIEDDALIMALTELDLDNETPEHPQQAPQRGAYREAQLEEELAQLQSQFAKYRNAVEQTLDQRWGEDTLVAARGEKPRGPDDKGVRKDESQYYWESYASNDIHETMLKDKVRTDSYRDFVYNNKSLFKDKIVLDIGCGTGILSMFCAKAGAKQVFAVDKSDIIDKARENVFNNGLTDKVTCIRGRVEDISLPVDQVDIIISEWMGYCLLYEAMMNSVLVARDRFLKPDGLIAPSISTIWVAPVSDPEYITDFVTFWDDVYGFDMKSMKEGIYDEARIEIMPKDCICGTPSQISYIDLHTVKIEDLDFETQWKSNVTKDIPSLDGFLTWFDIFFTTSRNDSIPADLQVKAGETSVTRPGEVAFTTGPAGPDTHWKQGFLMNKYLEENASVTAGTEISGRIVFKAPENNPRALTISNTWTVPGQDSRKQLWKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIK5</accession>
    <name>A0AAD8UIK5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_654969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361265.1">
        <property type="nucleotide sequence ID" value="XM_060510768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIK5"/>
    <dbReference type="GeneID" id="85394667"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056023">
        <property type="entry name" value="DUF7603"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24554">
        <property type="entry name" value="DUF7603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7603" evidence="3">
        <location>
            <begin position="840"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="955"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="655"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="617"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="957"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1101" mass="122114" checksum="189CC256508189F3" modified="2024-05-29" version="1">MAARDPRPPHLNLHLERPPRATGDPSNPETLNASSDDLRGRPPYRDPNRPATSPSPSPGRTRSQTLPVQVITPTFNPAKAIKRKPLSSTASQLAASYGTGSGSSTPSILSPSAFAAPETRFSRSYSVDSPTLYEFSDNNVRPLFAPPAAHQKLDIQPPPTDPADDAAYFASRNNPSTNLASPQTKPSDGLSEPAFLTSDVTPTFSPRLPKATPPQPIIEEEEDTDEDSESIYSHNTNDNSIMSIPATKPTPLHLNLSTDRDNSSQTVTTVLELRQSLTPTTSTPTPSINKPLPKSPGSSKLANFFGWGSSPSPSTTEFSSLSSPLNSPRRATLTDDTPLTTGVPSLLPEPRKGNATPTNALGYCESNLYTPPPSSLAPSLQIEEMEDELKAISAELASSIRREMDLEDLVDRLQSEINNPQAPGRRTSDYFSDSGYSSAKFSEYDQSKEEVEKIQRRAEQERASMRLELTNKLQDERSRRNELDQQIKELAEKASQVDVAQINNEDTNNRLRDLEHTCEDLRRRLGDEVQVKSNFEDLLSVLKVELQSTTNERDNLRDEIVPQLKSKLDGLEAEASEYANLTYESSKMQQELEVLRQENKALKSSGPPPSQPETRARSATSSSTRLARSSSVTAMPFILQKAPSGLGLTRSNTVKSGVTESREQLSERLKDVEAQRDALHNALKSLLERQEFQNRENEKKIKTLEVERERLMVTSPRQAGFAKDISNLRVEVNVLRRRADEAAEQKWQVEKGLAGLKMDLDRAEGEVAALRGLLKEKDILIPPSMARGSTYESASVPVTSESLEAAFQDLQLAYKDSLLRIKDLESSGSMVVGDEATRLALERLEQSLTSAVFERDAAKEEASAYKDQLESLAGSEVAHLESERALSDELRTSAQRVEELASQVQNQLSVNSELRQRLAEAVARGDADRKANADRITRLQSRLKNLEEQLQAAQISSEERVARHEEQLKELKDAQSVQLRRMSPSPGANGMRSPRKASLSPMPSPMFPRSPRLMPKQSVEDETQIERLRVKVVELETALTVADSEMQDVIARMSTAQIEVLTLQEEREAARRETRRIQQELEKERMKAFEDRFKTLGSSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIP6</accession>
    <name>A0AAD8UIP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ThiJ/PfpI family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_779066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364681.1">
        <property type="nucleotide sequence ID" value="XM_060515508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIP6"/>
    <dbReference type="GeneID" id="85399406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26393" checksum="A44CC1EC4FB08D08" modified="2024-05-29" version="1" fragment="single">MIPRHIPNLAPSVEICYISVKASPKVDHLPLLPMTAGVRIQPTHDVSSPEVQPGMLDILLVPGPDPGASWNEETLAFLRGHADEEKKEEEEEEEEEEEEEEEEEEEEEEGNRKKTDVLSVCTGAFLCGAAGILEGRKVCGPRGLQDVLKKKFPGAKFVGDEFRWCRDGNLWSCGGITNGNDLVAAYARSSERRLFPGPIVEIACKMAEVGERGQVYEQGQTRFALGFVWQLVKAWSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIQ0</accession>
    <name>A0AAD8UIQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_620929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365097.1">
        <property type="nucleotide sequence ID" value="XM_060508222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIQ0"/>
    <dbReference type="GeneID" id="85392121"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="60" mass="7200" checksum="F65BBA324B389DC4" modified="2024-05-29" version="1" fragment="single">MLARPVHYRSTRRCSVVRHTLDRGQLSRAIRQLTAHFQVRDGYWRWYWWSSAALSAVLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ36</accession>
    <name>A0AAD8UJ36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_415694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362729.1">
        <property type="nucleotide sequence ID" value="XM_060502944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ36"/>
    <dbReference type="GeneID" id="85386843"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="169" mass="18482" checksum="F8A8A386E2E20D00" modified="2024-05-29" version="1">MLRARGAKLARGEQNIRRAARPLSDDPGLTMGSFPVVVDFGTNRADGNLRPKPVSAALPAEYRDMITDYLPRLPDRLTESISPLLTRGGNEETASSGRISNLNGILASSWHRLDLPIDPIMELLGSRKPQKITVFYPPVAAADPVLPCVPVSICLKGEVPTEKKCQERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJZ6</accession>
    <name>A0AAD8UJZ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EC65 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_311293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365371.1">
        <property type="nucleotide sequence ID" value="XM_060502309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJZ6"/>
    <dbReference type="GeneID" id="85386208"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041255" description="EC65 protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12290" checksum="5FB5C8D38CE1B46E" modified="2024-05-29" version="1">MKLSLLATITAVAITSTEACAKYKTCWCERSNFMYEGRLQDNIPWDEDTVKACVDPGTVGYYGQNFKECHRYKKSFFAFIPSKAINNCDWTKKCQSVGATTGYCREKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKY9</accession>
    <name>A0AAD8UKY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363498.1">
        <property type="nucleotide sequence ID" value="XM_060510588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKY9"/>
    <dbReference type="GeneID" id="85394487"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="28098" checksum="D92584F9EB30665E" modified="2024-05-29" version="1">MYSGVGTPASGTSASRLRCSQWGGGAPSGDLHDDTAGKLDRSVCEPVSIPSWPPSQGRCMDPVIEPFVNETVTDTVTATATKSLKDGQVFHRFPGSDGAWDAKNSPAGCVKAAHESCSYDAFPDRVHRRYFPCERRASICIGPIHSGALLPVRFEQYCNGSKKSRWGTKSDKATALVICLTRVNGGQPQRRYLQDSRIAGGDAISDLLHQVGLKFATQVAVCLEHRQLQSSQKPPPRLLVIGERDSGQHLVRLSSPNVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL01</accession>
    <name>A0AAD8UL01_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_583186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362450.1">
        <property type="nucleotide sequence ID" value="XM_060505627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL01"/>
    <dbReference type="GeneID" id="85389526"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="408"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="553"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="626" mass="70358" checksum="47367F315284FB08" modified="2024-05-29" version="1">MNGNDMPIKQEGVGAPAGVWTTPTSQGMRPRPATIHEGFSYSMGDDYGTLPSWDSSPLPMQQTPSDAMSRPVSVHQQDFYPVTTMENNWQQKPCEDTFEFHGLDTEMIGQAYTTDEAIPVLDLRYQQQDNEPFNFDCGPNPRRMSGSSFTMSTSGALSDMPSYEDFSAALSEAPSFSSDYPPPSNRNSLMSSTQLSPVASPRMTPQSRSELVRTQSRGRASPSPRPGMRSAPYSVERGTTKRWSTGSYGTQQNRRQTPFVFHQGHDAFGAHQRMSSRHSSPTIQHQQVPLNFTNLQAAQQHPFMMAAPPQYQRNSMNSMLLPSQLPSNGFHPDAHHFEAPPPLLSHGLFRMLQSNADPHSLHSHYTDLSDPPDLYASLHEEQIPPPPEDMNPSDPDLVPHEQELRFEGDLYTPRWVRGHGNKREGWCGICKPGRWLVLKNSAFWYDKSFTHGISAATGNPFQEPQETRRMDGNPDVWEGLCGSCNDWIALVSSKKKGTTWFRHAYKCHTHPKIKDAPKRRRESNHNRNLAASQMAKPKVEPQQPQQAPPMPQQTPITPQTSSASVTSTPTPAQMQQQHQHQHQVQQHQHLQQVPPPMPQMNQGQMVQNQVQQRNVINPMEGMPGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULF4</accession>
    <name>A0AAD8ULF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_794162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362675.1">
        <property type="nucleotide sequence ID" value="XM_060515800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULF4"/>
    <dbReference type="GeneID" id="85399698"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="20106" checksum="7BBE001FEA3C6A3F" modified="2024-05-29" version="1">MSTIVPEWSIVDSGQSFRAWEPSSACGNTPTEARASSCIYDDVLLHWMPTQCSSPELIDEFEHVWPWEFFEDQNATKAITLPQVMEGTQDIKWVSMDLHRWHCVATWKILSSAARWKTTVPAYAINWNHSTHCADHVLINMHVEDPFAINSHLDIEYTPCVTLAEDRSLEKATEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULM9</accession>
    <name>A0AAD8ULM9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Cutinase</fullName>
            <ecNumber evidence="3 13">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_581065</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 13"/>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363394.1">
        <property type="nucleotide sequence ID" value="XM_060505419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULM9"/>
    <dbReference type="GeneID" id="85389318"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000235">
        <property type="entry name" value="Cutinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF3">
        <property type="entry name" value="CUTINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041779671" description="Cutinase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="49"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="190"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="23470" checksum="120E7F15AFA0D766" modified="2024-05-29" version="1">MKFFSILSLAVTLAAAAPVEVADTAVADLQVRQTGATSNELESGSSSACPKVIFIFARASTEPGNMGISAGPIVGDALKSRYGSSQVWVQGVGGPYSADLASNFLPEGTSTVAINEAKRLFTLANTKCPNSAVVAGGYSQGTAVMASSISTLSSTIQNQIKGVVLFGYTKNLQNLGRIPNFPSSKLSVYCDVADAVCYGTLFILPAHFLYQTDAAIAAPIFLAGRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM04</accession>
    <name>A0AAD8UM04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_721078</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362900.1">
        <property type="nucleotide sequence ID" value="XM_060512345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM04"/>
    <dbReference type="GeneID" id="85396243"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF5">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="160" mass="19089" checksum="1FB06665E272F2D5" modified="2024-05-29" version="1">MPEKEERILGFNVHSICEDEFISPYNLQGPDLPCYSRQELSWPPYLRPTEAQKKITHHPFLDVFPFPSLREAGIRAEELGFFDEDDFCLDIFHLDDKKDGVERPRMIVWGESWDPRGWEVNVAFLRKWGWMVRGCPELLEGTNYWREKRGEKKLNFNLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMB7</accession>
    <name>A0AAD8UMB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium/proton exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_653435</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1722995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363050.1">
        <property type="nucleotide sequence ID" value="XM_060510614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMB7"/>
    <dbReference type="GeneID" id="85394513"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="191"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="425"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1722995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="62645" checksum="08B03AEEBD1DC718" modified="2024-05-29" version="1">MPSLIGSVNHFDIKRKAHGLSRRSQEQTWNPFRHVSWENQPHKRSTWDGANLEAQREVPAEERETDEAIHHVQSEPAPRDSETVRNSLGKETRSGTGSGSGDTMFENKPEDGGVRNRKTENSQGEDLPQEEEERPKAKKQKSGMIRHVQPKTPFTVANQLQRTLLSSYINILILAAPAGIAISYVSSVNKIAVFVVNFIAIIPLAAMLGFATEEIALRTGETLGGLLNATFGNAVELIVAILALAEGKVLIVQTSLIGSILSNLLLVMGFCFFFGGINRPEQYFNTTVAQTAASLLALAVASVIVPTVFDKNDGTDNTVHVAALSRGTAVILLIIYASYLFFQLKTHNAVFNEESQKVAAKPWSRGGLKEGALARGLAGTGARMAQTGVRGESENERQELSRMMMQRHEEEEDEEEEPQLHFLVAVGTLTGATVLIAFCAEAMVSSIDYVTKEGGISEEFVGLILLPIVGNAAEHATAVTVAIKDKMDLAIGVAVGSSMQVALFLIPLLIIIGWGMGNDAMTLSFDLFQVAVLFVAVLLVNYLIADGKSHWLEGLQLICLYAIIATCSWWYPATGVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UML3</accession>
    <name>A0AAD8UML3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_652680</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363904.1">
        <property type="nucleotide sequence ID" value="XM_060510546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UML3"/>
    <dbReference type="GeneID" id="85394445"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.80:FF:000003">
        <property type="entry name" value="DNA primase large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="304"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR009449-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1723849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="58814" checksum="B97C1D14E569A75D" modified="2024-05-29" version="1">MLRHDFNRIDPKRRNVVDHRKKQFASPVYKELEYPHRLNFYTDAPTADITLEQFEQWAIDRLRDPQPVLAELEACAFRNKSPQEVANHMKPILDKYLPLESNTSHSPKLFAQRQKDHYSHFILRLAFARTEDLRRRFTRVETMLFRLRFNSDDMSERAAFVGSLDLDWWEAVTDDEKREYSSELAAMSRGWGKTAATEDDTWFKVDWARVPELVEQRKVFLKAGKAFVPGREQASMVNGEFVSRLERQLELTARALPRLDEDDRLTPILDHLSKNFITPDSSYSSNTGAPPGAEITARNIDNLSQHFPACMSHLHRSLRRDAHLKHFGRLQYSLFLKGIGLNLEECLVFWRQSFRNITDDTFNKEYRYNVRHVYGDVGGDTNRRGGGYSPFSCQKILTEHPPGSGEAHGCPYRHFNLENLTTLMQGMGVSDRATLQGVKEDKENQKFHMACNRVFEHLHKQELKKAKDEGVFTSAQLETIVHPNEYFKRSYLLKNLDKATDVKMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMN9</accession>
    <name>A0AAD8UMN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_780284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363949.1">
        <property type="nucleotide sequence ID" value="XM_060515531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMN9"/>
    <dbReference type="GeneID" id="85399429"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF14">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34671" checksum="DF72A19FC19A7AF0" modified="2024-05-29" version="1">MKEIYQSVPEQDSTDDLSNSSTWHKSRQIRGQWSLQSKVIAAINVIFFFTSCGILFISWRWLNDPVRLMKRVSPYSPILDDVPIQLESVEVKGTLFNDYTPPRIWREQPSEKVDKAWEDMARIEYFGVSGDALRKMGKDPKISVSIPEEWGVGSDKYLVEIDMQHQLHCLNAVRKYAYFDYYYGTNYKNISMAPQRHQAHLAHCIDILLQALTCNPSLDLISHNWMRTQENPYPDFNIKRQCMAHDPILKWQHENGISEQILKYKNLPRPEGFPEVEPEPSILKIGEDLGHHEGHLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMQ0</accession>
    <name>A0AAD8UMQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RAM signaling pathway protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_394036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363245.1">
        <property type="nucleotide sequence ID" value="XM_060502808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMQ0"/>
    <dbReference type="GeneID" id="85386707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019487">
        <property type="entry name" value="RAM_signalling_pathway_SOG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF54">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10428">
        <property type="entry name" value="SOG2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="151"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="981" mass="107492" checksum="C5D588E9CF2C5676" modified="2024-05-29" version="1">MVERMERPDRPSGPPMPRGLPENPAQGRRQLQKDAALGNIPPPPPLPPMPKDLRNLSTGASLSASSPMTSAQVIALARDAMQSALHENESQAAEASAVSNELKPGVTIDLSRKGIQKLPDEVVDIIKNELERLALSHNQVNSFPARFSECTSLRYLNVRNNQIREFPLPLCDLRSLEILDLSKNKLRALPPDIVKLASLKVFSVQKNRIEELPVALSDMVSLQVLKFDGNPITFPPREVLQVQASSPPNEGYLKESEVTEVAVTAHIKRFLRQHAMNGRAESDTAGEESSEGVETPRMPPIKRVVSGRFPIKVNGTDVPDIRSPNLIRPPPIPNRSHYRGLSQQNTAIRRPGVMPLTIGNVNERLRSNSETLLQATRGERPESRARRMGVVSQKATQLGTLDETQANNRFSHYRGLSHGSAMQPPPPSMSVKSPNSPAEPFLQRPIYVRRLSVLPERRRESKFYDPILEAAKGILYAVFQIHPMIQMLMSLTSDGSSKRSSLEIVFYNTNSHVEELEQEIQKHDPMVVGDEMAGRENENVHRACQTLVGAYTHVCTLLAGNIDSFIDNGDPRYIRTLLMLIYNSIMEIRCTLAALTPEGGLTKPPTRAMNMSDTIKPHSRDNSITPTADRLGLAQRPRPGPIMHNPSNLRVATDVPLPYLNGISGMNGMNGMNGNAASRTATLTSATPRSGESFASASSGGRGVSDFTEDDRHFERIFLSLRKSSKVVSHILPGFQTHMSVLAKRAMGRRAPEHEMMWWKALISRCGTAVQQTEMLQSRLSLIKLKEPGLMYQPAFRNLISNFMDSWCEFVGQIRKAFNEVSLPPDTRSRLRPIQQAMKEVTDTIVQSPWSYLLRESSNSNMFSPNGGPGLAPMQLPMTPQSAALGPAVQATVPSTPQSASFASAFNGGVFERADALISMGGLSMSRNGTMTNSSAASFTMSSMSSLSSDGGAMTPASVISPNGFGPGPVPLRLNGSKVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNJ8</accession>
    <name>A0AAD8UNJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase family M28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_750781</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366718.1">
        <property type="nucleotide sequence ID" value="XM_060513962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNJ8"/>
    <dbReference type="GeneID" id="85397860"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08022">
        <property type="entry name" value="M28_PSMA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02121">
        <property type="entry name" value="PA_GCPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000008">
        <property type="entry name" value="Glutamate carboxypeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146047" evidence="2">
        <location>
            <begin position="18"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="3">
        <location>
            <begin position="174"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="354"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="4">
        <location>
            <begin position="605"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="719" mass="78547" checksum="67EBA761C17EBAB9" modified="2024-05-29" version="1">MRQTLLSLALTATSIYACQRDWAALNRRIERHTHHDQGHKKRDTAVEYPPSLTEFESILVNSFDSKSLDEWSHYYTSGDHLGGHNRTLAEWTQQKWIDAGWDASIEEYWIWYTAPLETTLTLNRPDGSVHNVSLIEDMLEEDPTTSYPNRIPAYHAMSGSGNISAEYVYVGRGQRGDFQALKDAGIELEGKIALSMYGAIYRGTKVKNAQDNGMIGAVLFTDPLDDGEITVANGYLAYPDGPARNPSMIQRGSVRFSSLYSGDPSTVGYASEKDGPRNDVTAYNPTIPSVPISMKDAVPLLAALDGSGLSAEQINRSSWIGALPNITYSSGPTPGATLDMVHFMNQTIAPSWDVIGVINGTHPDEVLIIGNHRDAWVIGGAADPNSGSAVLIELSKAFGKLLDKGWKPRRTIILGSWDAEEFGLQGSTEWVESHLPWLVTNAVAYLNLDVAVSGPRTALSGSGEIQTVAIEMMKKVLFPEDWGVGPTLYDMWFNTTEGEIPPLGSGSDYASFYHNGISAIDIGSDGGKTDPVYHYHGHYDSYTWMAKFGDPGFKIHRAMGQWLTLIAYHIADDVIIPWDLPNAGRVLRTYYEDLNETIVEDYPGLSLSPIDEAITEFEAAAERIATVAKQALAFNDTVLIDVINGKYRDFSRGFASAGGLPGRPTFHNVISAPGLDNGYGADVFPAVQDSLSSGNETQAEEWVDKSASAISRAAEILSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPY0</accession>
    <name>A0AAD8UPY0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_650755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366195.1">
        <property type="nucleotide sequence ID" value="XM_060510399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPY0"/>
    <dbReference type="GeneID" id="85394298"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF2">
        <property type="entry name" value="ARYL-ALCOHOL DEHYDROGENASE AAD10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="389" mass="43016" checksum="4D2A4B40906AC167" modified="2024-05-29" version="1">MATESARTLFFPAPDPPTPLARYRVLSPNAAIRVSPLQMGTMSLGTAWSDGMGPVEKNAAFSLLDAYLDAGGNFFDCSNGYQHEQSESWLGEWMEVRGVRDRCVVATKFSADYRMHALGKGRCPNAGGNSRASMHMSLRDSLAKLRTDWIDVFYVQWWDYTASIEEVMDALHNLVQQGKVHYLGIANCPAWVVSAANTYARAHGKTPFSIYQGYYSVIMRDMERDIIPMARQFGMAIAPYGAAGMGKFKTRDMIEARRRSGDGQAAFRHLADQTETEIRVSKALAEVAEEVGVTSITAVALAYVVAKVPYVFPVVGGRKVEQMLDNIDALTIQLSEAQIAYLESVEKWEPGWPYDVMGWDPHVSGTPAPIIAASAKMDFVRRPKAIGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ52</accession>
    <name>A0AAD8UQ52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_611574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367981.1">
        <property type="nucleotide sequence ID" value="XM_060507665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ52"/>
    <dbReference type="GeneID" id="85391564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="19094" checksum="BDAE7ECA3B478F0D" modified="2024-05-29" version="1">MNWADQFDGHGRSFIYEEDGQPITQHTRPVLPRSNPQPRRPPPPPPKRSQDPHENIHAWLSGVTIDEEHVPLASDIFHALGQIQSQTTGGHQAPPVDKQQQQQTQTETQTAGPTVTVHTMGPGFIGRAPAFGTSEFFANMVVVGILLLFAPGFTILAAGVFFTSRVAERWAGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQG4</accession>
    <name>A0AAD8UQG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">VTC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_610230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368161.1">
        <property type="nucleotide sequence ID" value="XM_060507579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQG4"/>
    <dbReference type="GeneID" id="85391478"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000002">
        <property type="entry name" value="Vacuolar transporter chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="727"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="570"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="754" mass="86525" checksum="3113F2DACC75A0BF" modified="2024-05-29" version="1">MRFGKTLRLAVYAPWKDKYIDYAKLKSLLREDKYDDEDVAWTEDDENRFCDEIFNGQLEKVAAFQEQTFEALKDRVEAAFEKLKELAPPTSEEDEGAENDQIKKPDAATAQKLKDIETELDKITTEISELKKYSNINYTGFLKIVKKHDRKRGDRYKVRPMMQLSLAKRPFNSEQGYSPLLNKLSIMYYAIRQQLDEGSGDAQPLDLESQGETRHGERYTAHKFWVHPDNLLEVKTYIMRRLPALVYSEQSAKELDGSNDPTITSLYFDNSKFDLYGKKVERKAEASSVRVRWYGQLSAKPELFLEQKIVGEQGSSEERRFPIKDKYIKPFIDGTYKMEKTVEKMERQSQQAEVVESFKSTVESLQGFMQENKLQPVLRANYVRTAFQKPADDRVRISIDTEVAFIREDTLDRDRPCRDPAEWHRLDIDGRNLTYPFKDINQSEVSRFPYAILEIKLREDPNRKRPAWITDLMASHLVHPTPRFSKFVHGIASLFEDFVNNLPFWLSDLEADIRKDPQVAFEAEEQRKAQRAEDEQAVGSFLGNKVSSYKISKSSPAAQSYLANRMAAESSRSQSRPVNDESQQSSSRQNGEGSNGQQRSYGTLSSVLPGFSLSKYSQARRAQKNQQQLPEGVVEPTEWIKNSGELKIEPKVWLANERTFLKWQHICILLGALAVSLYTAAGENFLAEVMGIVYICIAVFAGVWGYGMMRLRRKMIIGRSGKDFDNLVGPLIISIALMAALVINFVLAVSFPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US85</accession>
    <name>A0AAD8US85_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_790932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366843.1">
        <property type="nucleotide sequence ID" value="XM_060515725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US85"/>
    <dbReference type="GeneID" id="85399623"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="76649" checksum="6824CC48636BFB0E" modified="2024-05-29" version="1">MAEAIGLATSVIAVAEVMGKAIGLTLKIKSLWREVKNVPTVLLEKAEELQDLDDYLKDAEAQTAGSPISKSIINDEIMQKSLRRARAALADIQNTIDGLGLQMSDPRKHRRKLTAAIFILQKDTIEDMERKLDRALELFKVAQGIYCTNLTMLSTSIIMDQLPKCLSSSKVTKSSSHKVKVTEFVEQHKPFVANIAGKDNLGISQGTTAIGRLRLGFGDNNFQISLRSPSWLGNKVYSAMCHKSMIGWQIHLTAYVVIKSFRGIEDSVKSDNPQALMKHLRSTSLTPLVEDANGQNLLYLCAENRWLNIAKWLLSFGLFAGSYSSEENNCLEDSRSRTLIFEADNKLWHPPNSHIPPDFIILFALQAPDGDTGVSVESMGFIAGLTDFDNFTRLLQSKSPASNPKWYYLASRLRFAYSGIRGSVWTLSQLTAVLPELKSLTRELVVSWRLAGRKYLIPSLVASGIGARASRAPRGDPAYSHSVNEYARLAGQIIALDPESLTQAATTRHRASSALHMLMRTLLSNFQPCSTDQADYIIQSTLQVWVKMLHGNKVNLLHHGRQSRTTYTVPRRHVPPGWSFRLLQNTNEPRKRNKKRDREYRIEYIGITYGSLPEHWKVWWGVDFEGYAGEFWRMLEDSGIKIPGSWVDDAVFDDGSAKLVPSWVHEGTGSLIWSEHRKIRPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USK1</accession>
    <name>A0AAD8USK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_616342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366394.1">
        <property type="nucleotide sequence ID" value="XM_060507968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USK1"/>
    <dbReference type="GeneID" id="85391867"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF35">
        <property type="entry name" value="ACYL-COA THIOESTERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="3">
        <location>
            <begin position="31"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="4">
        <location>
            <begin position="209"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="36503" checksum="C0650B64AFE682E8" modified="2024-05-29" version="1">MSHGSMASTMREQVAVDDLGSDHFTSRVDPARMGNKANIAYGGCTISIGVQAACSTVSPKYLLYSATGNYLGPALTDRKLKCTVRRVRDTRTFATRLVEISQDQDDGKPRLCMIMLADFQVKEEASLLVYSAPPSMSYSPPEKCLTTQEATEDKVQRGVVTKKLGVLYLATFGFNSRFFETRGCPETIAPNNLYGMAKTVKTPQESLDLTSKTSADWFRCRHPLERLQDRFSALGFILDAALSFIPLTHSSKFLDDAGPCSSLDFALRFFTAEINLDNWHLREMKTIAGNDGRTYTEARLWDQQGNMVATMNQQSIMRPLKKDIQAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTT1</accession>
    <name>A0AAD8UTT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_612449</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367664.1">
        <property type="nucleotide sequence ID" value="XM_060507713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTT1"/>
    <dbReference type="GeneID" id="85391612"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="284" mass="31368" checksum="BA77E1E53EF82F31" modified="2024-05-29" version="1">MLSVAKGIAQVLTLLEIMAKTMSKPWNLPSGGSATHPEVQEQVVQHPARHVVVFWRLAVPYRGQHVLGVRADVVSASQMACHALHRPHAPLSPPQLFDSHPLGISTVKIPKVEQGTRALEDHGWGPARWLPRSRGSPSLCFLNCGGRRSATASNAALLAGQACTSTTATLTINQPFVCRKILHSNYGCGRSMEYSRPRRDWDQARMRFYPRHQGAIRHHPSCSLLSKHLMWRRERGGAVSTTIPPLRTGNPNTSEIHTDRCNAEQVIVAPSDSIHNTASWTFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV88</accession>
    <name>A0AAD8UV88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_614372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366980.1">
        <property type="nucleotide sequence ID" value="XM_060507830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV88"/>
    <dbReference type="GeneID" id="85391729"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="275" mass="30209" checksum="C25033A15B5702D2" modified="2024-05-29" version="1">MDSASSAEEKDPDDINVDYTTMFVMEKPQIYRSMLAPKWLNMRWTVSVNNLSFNATSFILYPSPPKFTSGDPQNVFTCVYQQSQSINARTGSNEFGIAMQGVGSHPIFVVTGSPHHQLEPGLQVYATDTCETYLAENPQTSCNMVLPKDAAASFTPGSGRVDKNSTSEKASIRISCDSFAGNDKARPFVGLGAPAPFGVGIVPTVVWKAVPNQSFHLAPMSNKWRIAKSTAKTKIILDLSSQMPSDWIEVEFTEDNREIQIDHNTDGTFSFSSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWD8</accession>
    <name>A0AAD8UWD8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_138567</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368329.1">
        <property type="nucleotide sequence ID" value="XM_060501264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWD8"/>
    <dbReference type="GeneID" id="85385163"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000489">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="98"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="620" mass="66896" checksum="C543FFABEBEFA82B" modified="2024-05-29" version="1">MFDAQKAAVPSFMAPPTFLQSRASTLTPSDSSSNYDEMEKDIASSAASFQDIRIDPILLPPVPYSELSRIPSIKSEQAEIVNNEDDLEYPKGMKLALIVMALCFSVFLMALGKEHPPPNSTPIQQGRATADHSHHLDNSIIATAIPRITDEFKSLNDVGWYGSAYLLTTASLQLLFGKFYSFFSIKWVYLITIAIFELGSLICGVAPNSIALIIGRAIAGVGSAGIFAGALIILAYSVPLEKRPIYTGAVGSMWGISSVAGPLLGGVFTDSLTWRWCFYINLPIGAVTIFVILFFFPDPVRSIPQETWRTRFIQMDPLGNMLFMPAIICLLLALHWGGVTYPWASARVIVLFLIFGFGMAGFLYLQYLGQENATVPPRIFKQRSVWSSSFFAFNTGAAFLLSVYFLPIWFQSVQGVSAVNSGVRNLPMLVSNIIASLVAGAAVTIWGLYTPWMILGSILMGIGYGLISTFNPNTSSAMWIGYQILAGAGVGAAMQQPLMAVQVVLDMADVPTGTAIIIFTQTVGGAIFVAIGQTVFTNKLVESLVEYIPTIDPHSVIAAGVTAIRKTIDPSLLPAVEHAYSDALAQAFLVSAVTASATIIGSVFVEWKSVKGKDVHVGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7K2</accession>
    <name>A0AAD8X7K2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_758842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000275">
        <property type="protein sequence ID" value="KAK1703775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357340.1">
        <property type="nucleotide sequence ID" value="XM_060515099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7K2"/>
    <dbReference type="GeneID" id="85398997"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1703775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="13900" checksum="4293D8616E0C45A3" modified="2024-05-29" version="1">MDPEQYTPEDGPFVTVLDTKFGTLYYKISADNPRDSPSTPQVVELAVAIMEQRLTNFPLRPNGFNVDPDTELKVRFGNVIEQVGDKIPREKLFVTVKVQDPKKEISSFLPDTLSLMKLKSVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X879</accession>
    <name>A0AAD8X879_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine rich repeat domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000209">
        <property type="protein sequence ID" value="KAK1707522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358059.1">
        <property type="nucleotide sequence ID" value="XM_060514999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X879"/>
    <dbReference type="GeneID" id="85398897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="89285" checksum="91A407F69D10223B" modified="2024-05-29" version="1">MATLPSYQDAVSKLDWLELVAPYVADKDFTSLCSVNKRFNAVFAPRLWNDPLVAARRLGLDPSDDLEWYLTFVFDRMQRLRPKTLALIMTLDFREFAKDTAHFLSDSSSRTIPHTLRQLSKTLPNLRCILLDGHAEADPAFLTTIPVSEANTTPPDPRQGLLVLSVAHCQNQLPNGFYASDKLQQLVLLDVSGLPGSLQALIAAAHGRCNLRRLKVLKVRRREINDFLALMLFQAFKSSLWSLDISENRITDGILGQFAALCFNSPSLRSQSRFKTEGKLVFDGQGNDTFGPFMFIQESDSSATFSDTERHFVDAPIYSAVAGRDLQEDEAVRANGRTPLRRDTVDYVKAATAGGMDHLAPNWSDVSYLDVCSAPTGITHLHISDTQITSSGVGRLLRSSQGQLEELSCDGPLFLPVQGSALKQQHLLPWPKNVTLRGALGCVHVFRPVFSSNLRVLRIHHSLVTQIPTLETDGLSTMARLWLAETVVRERSEMAFPQTFEPDMNPRLTSLTLTKIPRRSNGPLIDTLVQFLTLAGLQERAIRKTASQSSSRRGSMLLHGLRHLRLEFEADPVEDPAGFSAADDLDAKELLNMGEDEGFSFFGDERRPQPRPEPTRKKQATAGGQVATHHSQPATVRLSAFPYSDFQGVSMPYHDTWGGSQFDRIIWVGDGILGPNHLAVNEYMKLVTNPLLRSRVGPAATVHVKAGVPEGVLIFHAAWDAIVMPPELKPPRAAELHGMRDVLEAIKAFRIETRAAYEPAKKAAVEGVAELDTTSGPRHYFWSGRLEVSAQQSMAHYRAPGYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Y1</accession>
    <name>A0AAD8X8Y1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline monooxygenase, chloroplastic</fullName>
            <ecNumber evidence="5">1.14.15.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_757829</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the first step of the osmoprotectant glycine betaine synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>choline + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = betaine aldehyde hydrate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:17769"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15870"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="EC" id="1.14.15.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (monooxygenase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the choline monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.7" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358477.1">
        <property type="nucleotide sequence ID" value="XM_060514948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Y1"/>
    <dbReference type="GeneID" id="85398846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019133">
        <property type="term" value="F:choline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00680">
        <property type="entry name" value="RHO_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03469">
        <property type="entry name" value="Rieske_RO_Alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015879">
        <property type="entry name" value="Ring_hydroxy_dOase_asu_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001663">
        <property type="entry name" value="Rng_hydr_dOase-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43756:SF5">
        <property type="entry name" value="CHOLINE MONOOXYGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00848">
        <property type="entry name" value="Ring_hydroxyl_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00090">
        <property type="entry name" value="RNGDIOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="45"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1709138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="413" mass="47354" checksum="8031553848CAEC73" modified="2024-05-29" version="1">MLRFLGLSSATSDAKPEPSRSLPASWYRSPELHQLERRAIISRKWILVTHSLRFKQAGEFVSFVYADFPFFLVQDRDGNINGFHNVCRHRAYPVVEKKSGKASILSCKYHGWSYGFKGNLAKAPRFDTVTGFDKSQNGLLPIHVRVDTAGFIWVNLQAGEPDVKWEDEFGGVYQKPRMQNFDFSGGYKYDHVWDMELEANWKAVIENYNECYHCPTSHPLIAGVSDLTKYQVKPSGGCLEHEIINKKAQDEEDEFRRSITFFYPSTSVTITQNFFYIQRMIPISATKTRIENEVYRSHNSSDAEFAAINAFYKQVLEEDRDLCIGAQENLSAGVFISGELHPEKERGPIHFQNTVREEVMKHRQRELEQGGREIWPATPNLLGQTRAGKLNEDEAFCSELEKANCGGREELAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA50</accession>
    <name>A0AAD8XA50_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alcohol acetyltransferase FCK4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_757627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358721.1">
        <property type="nucleotide sequence ID" value="XM_060514921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA50"/>
    <dbReference type="GeneID" id="85398819"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="59694" checksum="C46ECCDA38B66F32" modified="2024-05-29" version="1">MATTTSVIATKGASDGMPDSGHYTIVRKTTNLDRMFYVYHRLGIQSNVLVAARYASAQQSRQRLILSDDAVFSALHAVVTKFPELGLVGVVGPAAEEGKHLLSLATLNEINLERCVEFINDETTQVDAGFLQKLHGTWHWADGAVEAGVPWWKIIVVGRRDVVFVYHHLVCDGAFGMTFHRELLDALNASAVSDTGSAPSRIIKLDPDRVRLSMALENTIHKKPAVLGVIYNLLVFLFYRFFYAKKLFFVNFPKPKELLKDPMAVAGPADRTVTKVTTHRIPSDKMDAIIKSCRAHDTTFTPFLAVVVAGTLAADFYPHAEVGFTRYAVDMRATGCFDTASPDEGKLLNLAASLPEPEKLRKYRQAFSASSSVGDKQKGLTATVDSKAAWDLVRDYGRRMVESRSGGDESHLYKAWISGNALGPSLEEFAEKLPSMGLFMQNSFSVSNVGCLKTAPPSSNVEEPVVKIEDVQFSAGPVQGAVGYHGIVFNVAGVAGGDTVINACTEGGMAPEGMVEAVLDGVMARVNALLQEEGAPKDSTGRKGFWHAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA63</accession>
    <name>A0AAD8XA63_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000306">
        <property type="protein sequence ID" value="KAK1702570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357159.1">
        <property type="nucleotide sequence ID" value="XM_060509828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA63"/>
    <dbReference type="GeneID" id="85393727"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="11"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="58353" checksum="4021092A6835A61E" modified="2024-05-29" version="1">MVQGIMALSTFPCFLSLPFEIRREIYWLATLPRIVNVEEKTDIGFDEFREIVNTHPVQLQVHSDIEFFSVNWAAEIQRRIRDGRSHRQTTLEEHGFTGSKPIPQPWIPSAQCPEIPLAWLANEPKVAWELIREGYLYSKAPIPPLLHTCAESRGVLIRDGYRLAFATRTAEPRTWFHFDRDTLFLPQAAYEEEDRPELLSGGPWDVGQFTAADLRQVHRLALEGSAAVLYGADRAAPWQSVPATASVAVSLLLRLLGSVEELWFVEWTRRDVEHWGVFEPCLTPLRRSWEVPPMVEGSAVDVARRSGDFVAVNVELVDMTGPSCLCDGALGGQFLRSGFGALHFVRFMEDRRESGAGAGTESEAASYSGYLRRLRQVFLERQMAGILAKEHHREEVQMMDDGIDTGCWKIPETKLVHVLPRNMVQYIYEERQSVVAGLKALQTEWAYLTKQEVCSVGMGGEALRVNSSVSERQAFEDKHWPPNGCPHEDCQGTCYFRSVEDRIKKWWVQHGPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAR0</accession>
    <name>A0AAD8XAR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_724805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357713.1">
        <property type="nucleotide sequence ID" value="XM_060512695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAR0"/>
    <dbReference type="GeneID" id="85396593"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="318" mass="35815" checksum="5E771608AC77E187" modified="2024-05-29" version="1">MGGQPSWIHTQYCRDLYARSLQAGGDLEDAGGVFPDVAIWDDNGNRLGRYRTKLGDKIAQSSERTVKIPNNENKGQISDPQYVMLSHDTDATCIAMGDTGYKCGQACQRKFKGDNLMNQCVWLDSDHSHPNFNARAMSFHLRDMLPSPDKLKFYNSELSYMHLVPDGIVPFFYPVLKYNKDSINPKLEGTNESPIAALDRFKYNKDVYTQQGESEKDKRQGSNMDPDHLVLTEIPGQTAREICEHPNSVGYDIVSFVDRKYCDLTKRKLYDLCAGSITINCFDVNNTTVIGAQVLTGRSRSSTKGQIAKLYKTRAHCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB74</accession>
    <name>A0AAD8XB74_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HSP40/DnaJ peptide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_632613</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361314.1">
        <property type="nucleotide sequence ID" value="XM_060508982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB74"/>
    <dbReference type="GeneID" id="85392881"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chaperone DnaJ C-terminal" evidence="3">
        <location>
            <begin position="47"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="24119" checksum="85EBA012A6BCB8E2" modified="2024-05-29" version="1">MDDFSDIFSTFGGAGGPRGSRSSRMRSSGFGDSRGAREATPEVTTVERPLPLTLEELFRGVTKKMKIKRKTFDDTGKRTTTDTVLEVPIKPGLKKGSKIKFKGVGDQEEGGQQDLHFILEEKAHPLFVREDNDLVHTVELDLKEALTGWKRTVTTIDGKQLNLDKNGPTQPGSSDRYPGLGMPISKKPGTRGDFVIKYNVKFPTSLTPAQKQQLKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB76</accession>
    <name>A0AAD8XB76_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">LamB/YcsF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_756595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359906.1">
        <property type="nucleotide sequence ID" value="XM_060514770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB76"/>
    <dbReference type="GeneID" id="85398668"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11665">
        <property type="entry name" value="LamB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003814">
        <property type="entry name" value="PRK05406.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003816">
        <property type="entry name" value="PRK05406.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292:SF0">
        <property type="entry name" value="5-OXOPROLINASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YBGL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="28694" checksum="330E07B04C651CA0" modified="2024-05-29" version="1">MASGLARKYEINADMGEGFGRWKMGPDEELMPYIDAANIACGYHAGDPSIMLKTVRLCKKHGVKAGAHPGLQDMFGFGRRKIEIDPKDMYAMVLYQVGALKAILNSEGVELSHIKPHGELFFYMQRDETIMRAVLEACATFGDNIPVYASQNATQEAMCRELGIPFQGEVYVDIDYSPEGKLIPVAQSKVATPESCYERALSASLKDEGKDNSGGIFSFGFEGKPFSICVHSDHPTVLQNVTGVRNAVDEANKQRFPNVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBD1</accession>
    <name>A0AAD8XBD1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_755626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361027.1">
        <property type="nucleotide sequence ID" value="XM_060514639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBD1"/>
    <dbReference type="GeneID" id="85398537"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000028">
        <property type="entry name" value="S9 family peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="477"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="695" mass="77144" checksum="A037AA5D5AAD5AF4" modified="2024-05-29" version="1">MRVAKEFTPEVLLSAPRRGAAVPSPDGKLILYTQSTHSFEDNKTLKEVRLMHVESGASDQLTDDDKVHDALWLPGTASDIVYLKSGEKGTTQIWIANGAEPAKEHYVAAEYDAPISALKVKALGDGSVGFVVAGLVGPDGSLFNDKTEEKRSTGRIFDDYHMRRWNELIKPHKYALWYSTLVNAHGKWGVAGELQNAIKGSRLEAPSGMYDVSDPTDAFDVSDKGIAFIAEDTGLKPQDAGASHVYYVPLASFTAAATTKPRPLVMGISEAKAYYSNVRFSPDGSKIAFLHEPLDNPADARLYMGHTASFGAYDVHKMIFGRGPSLPPKGFEFAGSSDAIFLQTEDCGRVKLSHVELRHGAEATTLTSSGVVSAFYPLKEGSYDKVLVTSNSFLDSSLWQIIDVSLNTAPKIVSSATKHGAKYGLSHSMVSEFWYEGEDDNIVHSFIIKPANFDKTKKYPWILLPHGGPESSWTDSWSTRWNMALWAQQGYVLIAPNIAGSTGYGVDFTARIYRSWGGAPFQDLVRLMDHLQQVPYLDQDRAVVAGASYGGYMISWMNGHDLIRRFACSIWHDGIFSLPVFMLQSDIVDGGPDFGGPPFLWDNAEEMERWNPARPELLRNWRHAPPTLIIHSEKDYRCPITEGIAAYNTLMCQGVKTRFLTFDNECHWVLNPENSIVWHKTVFDWMARFTGESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCL3</accession>
    <name>A0AAD8XCL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_754052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362829.1">
        <property type="nucleotide sequence ID" value="XM_060514431.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398329"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1638" mass="184668" checksum="E94C276D4F405C54" modified="2024-05-29" version="1">MMADSTSIKHTILRNGTPKEVAKYLKGIRANAADPTSVTHNLHEAVVRGSIPHSIFSIWIPISDDAKSIVAALNQSGSTSGRRAAMRAFLKAMRSEDTMIPVWNAAGGAQGVATIMSNLSVKEVKMLCNGLARTASLPHGRSQRRAKLTELIAILGAGTPVPKENPDARPLLAHYRRILPACTTDRVAEHEGTSPKWTTRQRSNLLRTHPTFYEAKFLDSILSKGESPTAEFDVDTCTQLINNNFAFAKEMLLKFLDAGAELPITPDVFINQIALPIVKRLRRRRTAAQQHLPFEILELLVRLINRHPDLQRMLDDSLVGVMFYVIKFWEHTRSTRPRVEQHLVELLKLTPETRWQSAKQIVPHLRAVNPAVSYRLFRLMLRHLPAFKFDVDEAIGNEDISLEKIKGPWPARFFVTTLGRDDRLASLRLVQRLMAAFPDGRFLEYSYPRGSSIFEHEQDYDSVQGDAFALEVFLLRSSPASSPLNTSYDSKVDADLERRRKEASSSRDWESRALWAQSVLDLSIAAGSLDLYAENLLWARRFNKDVFTVRDLYDERSMKTAEGLDLLSGIEIASFAGQPDFDAAKSVRSANKIMMQLLETASMATREPSFQAYDWQTVIKLPAAVIERRFQLVNEFQDARKLTDTEISEIVWQPTVDFLVELETFLLRPSHQELNSLGSRGLGFPRDCLGAREKRSHTFKFADGLAKARDELWQKHRPQRFPSVLTLGEPWPKGLPLQSLLPTGFFGLKNIDAMPYIRERIEKVVFGAPEVLLKEPLRDKESQQAIGRFVDEYSFALKAYIDGGEESCQQEERTRKAWRHAVDSLSGVRMTKAEALRFWEQQFNCADVPLPADIKAEFPRRVEISIPEVGNPETPTEWNPDSCHTKFEELGSKKIPVTILDVMMSCNAFGLGRDAVWAALSWSDTVQIPPKEIPNFWDASQFSQPLSGKVVDAYFASLLLSLNTIHGSDSSVLKHPFPSEADFRYPALYLDEDFLETIDEAFFHDNQAQIEHIIKSGPPALLVPAVNSILQNVAANEDSESLTHARFQVAMKLVKVLAGSDQPSLAFPFIRDIVLNRPSDSAWHRELLTKGFFNAIPPKQAKKLLCMISIGIQEKLEEQQFRYEKAKKEGGELAARSPPVVKVTTVKMLAKLLSNAPFLDVTSAVDILSGLLSKAQHIDIRLAIIQTMFDTLEAETASPDVKNRILSVIEDLAVPLAASLDELHPMTEDDWTQAEADDTLSEVANVKDRSAAPIRSLFYNLEMKLCNDPVAKAKLVGITDRLILRSAENNRRWLELFLKKNDFSLPSGESLPLSPVDPAMLKIFQRTTVYFSRPMLGMLSRYVLANVRPSPGMAAVTKKIESNATLANSNAGRHWLQLFSGNEGTMVVSDWTYCLEQMHLPHMSKEVANPKDRITVAMLQRFAEDFADGLISHGDPSHVEALLEHKSEAMMREKNPETLKSWQLTTQPVLRSVIARVEELRTPSWQHDPMREPKALPNPFRLRVAMLAVPPGGADMDALFAKEISALIDELANGHAMYHNNWIHLKHQLARNYSVWTPRLVYIATILGDLSNVNVESPTLADYLRVETARDLIKQADYPKVRNDINKLKEILRTWKESPVEKFRSDQRDIARLPLFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCP2</accession>
    <name>A0AAD8XCP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361496.1">
        <property type="nucleotide sequence ID" value="XM_060512443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCP2"/>
    <dbReference type="GeneID" id="85396341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="185"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="61214" checksum="7B7F7902B15E468B" modified="2024-05-29" version="1">MDAGGLAQMNSTNFSSGNSLAMPGGGLASRRGGPVKPLSLSSATPGSNAADNGAPTPRTSRSHLLAGLRTAPKSATAANFSATNNANVASPTSQSFAARSNNLSSNMYAQAQGNQYNGPKTALPRYAGQQQQQQQQQQQQVYQSVPSSQHYSAEQVLAPPEIHFDEQEQMDPSLYAQLVATNMYLAQQQQRLQQQLLSVQAAAQQFQGLNLQGAQQQIQQQQLAMYQQQQQLQSIQQSMMGQMQQPQQQVYTYYDPVTRQQGYYIDQGQTDQQAQLTQIYAALAQQQQQQQQQQQAPRVQVSPPPENHATPYRTTTPPKRYESPSEVAPLPPPSANAFRRGHKKVMSLALNGNNQASLSPSQEPPKSAGPKTASFPLTPLSGGYGPGQGRAGEHPIRQPRGPPSIEELKAKPIAKMEGSKNFATRARRSAVHNLVRAGRERRKGPGSSNGSMSPVSESAEEESGTPITDNESDSGRSGSGSLAGDIDCSLPSSRTSTNGSWGAIGSDRPSSRQRTRKSVDSIGSNESGENSFASVFKNSAQRAGVEVADGQRKAPMLVLTSAEKRKSGILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDY2</accession>
    <name>A0AAD8XDY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_19153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361238.1">
        <property type="nucleotide sequence ID" value="XM_060501598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDY2"/>
    <dbReference type="GeneID" id="85385497"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="234" mass="26362" checksum="272EC4645C941F00" modified="2024-05-29" version="1">MIMLRPRVIIHSGAAVPWPSLYRTAGGRLRLPVMLRPLASTTDDMLSENSDRVICSRPSVEIKITNHVIGTLTVCHRTRQAPSLSQEFGSCVSKYEISKGHPKSGIIFSGDFLMPESSYWRRFGKQSLRRNAVPRRPALPTGTLDAALPWSSQAHGYLVRGWKKNPVQRSLMCLTRRTTTTEWVSDCAKSKREIPDLCARDEELFKSTTRTCGGIFQKESIIESHLIEIIHSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE34</accession>
    <name>A0AAD8XE34_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_756293</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360310.1">
        <property type="nucleotide sequence ID" value="XM_060514727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE34"/>
    <dbReference type="GeneID" id="85398625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase its3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="13">
        <location>
            <begin position="366"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="798"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="804"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="819"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="838"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="902"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="967"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="996"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1715511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111844" checksum="29A7C5C01F062E67" modified="2024-05-29" version="1">MPTYLTRENAPVYSPNSDFLDLDPNNTLDLSDRKHPIDGLSHTLPLRPSRSNNLHDSFDESSTSSTHASDASDSIPNQMNGTRPTSMSSLPNGSAGAGGGADFDYHDHDSHHHDQYNDYKNQKHPLQNGHTVTMPDRTAPPPPITIIKKPSSDTEQSSPTDNYLTPPSIASPAAGSIDHTIKTNGTSSPNYAPPAIPSQGKLANGHTTPAPAPSNASLSPDPTANNQPTSPQRFSSPPLYQSGGATPNGSTSTGLQPPNGGLKHRHTLEVPGTQSNRASKDGSDTGFSSGRFSPTSTTQRVRRASLNLVRRDTRSMQSDVPRDEVVPDEEALRWAEHYRQKRASKRKRKEEEDDDRVLVGTKVDEHHTNWVTAYNMLTGIRVSVSRTNAKLDRPLTDADFEAKQKSTFDIAGNELVPSAKYDFKFKDYAPWVFRHLRGLFRLDPADYLMSLTGKYILSELGSPGKSGSFFYFSRDYKYIIKTIHHAEHKFLRKVLKDYYHHVTENPNTLLSQFYGLHRVKMPYGKKIHFVVMNNLFPPHRDIHTTFDLKGSTIGRDYKEEDLDKNPRATLKDLNWMRRQRNLELGIQKKKLFLEQLQKDVVLMKKLKIMDYSLLIGIHDLQRGNEENLRGKTLQVFNPGGEQEDGEPPSVLLRTPSKLENARKARELRNMIRHERPVPMGQTAAQMPDELDEGHSRSGYIFNQDDGGFQATHEDNSPADEIYYLGVIDCLTHYGMIKKIEHFWKGLTSDKTKISALPPEQYGDRFYNFVEGITMSPEEAIREKQRKDQEQIEAAAAAERQRVASWSSSMRRRSGTNNIPPMPDYRPPPTPPSAPISPEARETVERAQQDARRSERHGASELNVPDVVLSTTKMNERRESGGQGAPILPVVEEAGEASSLGGRSRDGAASRDGDDHRPATPAKPSMEGRFAGLRDYAPPTPPKGHHLKPESQDSGYGALPNGNGSTMSREDSLNIKPRLSKDSLDKALPPLPKEAGGQSSFRMGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEI7</accession>
    <name>A0AAD8XEI7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tubby C-terminal-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_577698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364869.1">
        <property type="nucleotide sequence ID" value="XM_060505047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEI7"/>
    <dbReference type="GeneID" id="85388946"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087:SF161">
        <property type="entry name" value="TUBBY C 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="21858" checksum="BC14BF2FAE4880B9" modified="2024-05-29" version="1">MAAPAVHNLPQAGNSVGIFPQLTARQSETLVLKEKILSITGDSFDIKLANGQPILRVQGKALSISGRKAVYDMSGNHLFDIVKEHLHLHTTFAAQDPKGNKIMEVKNSFALIGSKATATFVSPQTGKTESLEMKGNWLSTQADIVDTNTGQVLGRIDRNMLRARDFFGGKQTYALTVAPGVDMALMCALCICLDEKKNDNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEN6</accession>
    <name>A0AAD8XEN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_760684</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360895.1">
        <property type="nucleotide sequence ID" value="XM_060515167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEN6"/>
    <dbReference type="GeneID" id="85399065"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06922">
        <property type="entry name" value="ChtBD1_GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 12" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922208" description="chitinase" evidence="14">
        <location>
            <begin position="23"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="15">
        <location>
            <begin position="64"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="16">
        <location>
            <begin position="118"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1717408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1148" mass="124157" checksum="DE09CD345B2A3561" modified="2024-05-29" version="1">MKLFKTAVPVFCLLLVASGVIAQQDYSCSSTRPCKLGCCGKNNVCGLGPSYCAPANCTSSCSAKSECDPGWGSAWSQREKCPLNVCCSKFGFCGTTKEFCGDKKVKAPSCPGGSSAGKRVIGYYEGWSTTKACNGLNPEDLLYTAYTHLNYAFAFIDPTSYKIANMQDSDSKFMPRLTALKNYNPGMEVWIAIGGWSMNDPDQPTKRTFSELAASKAKQDVFFSSLLSFINKYGFDGVDIDWEYPVAEERSGTPADYKNLVTFLKNLRAALGTKGLTITLPASYWYLQHFDLKNIQPYLDWFNMMSYDLHGTWDGTNPYLGPYVNSHTNLTEIDRALELLWRNDIDPKKVVMGMGFYGRSFTLSNPSCKSAGCGFSAGGIPGRCSASAGTLMFSEIQEIIDKGGAQVTTDKTAAVKIVTWGGNQWVSYDDEETLKLKMDYANGKCLGGVMVWAASTDDAKGTAIKALAKASGRTDLSKSLFAKAVSSDPSQCVWGECGASCPSGLVPVESSGSNASPLGIELGCNQGKRNFCCPSKNPPTCKWKGSPKFCGALAKNRCSGKEIEIAASTDGCWTGHKSLCCTKTDSTSTLDSCEWLGAAPFCSAGATFGSILGLGTTPVAGAFSFLSYGCPNKDKPKELTTGKQGEGGQQTCAYNGGFKSYCCKDPVPWKECKWRYGNTAWVQWKQILSGPLANLFFDFSTDCKTGCESGEVTVATDGFGCRSGTYSYFCCGNPNTPVEPKLPEISLCPSPANLPDLSTVPEGGSSPKNVFKEGDVFDDNCILPPTNKRRHMIRAARPHQKGFDSNGTSSEEAEHPVLAGMDTSDLFGRSLEKRGARDVAMKLCAPGKQSSSIYTQNYPGATSIIRTTGKAFTVAKQGVCAAVGITALTNLDPNTNWVTEHVFEKQEFRDAVEWMMDGNTPKGVALTAGKAPFTGVFDLNGLFQDTWPSKTYTTLTIVRDWAGNINDAFTGLLGRTSDAGLNNANVVNLQVCDADFNRYKEFIVAGSDFMSQATWKNYSPTGRIAILSDVIDTFAYRGEVSVITSYQKTYASLATLWGDFGRYALSKGVSYDFASAWKQIVPANLESQVSSARTLFESYVKSELTFWKSTAAATTYSPVVVKEMTDKLTDWQGKVTTLIALPISKMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFD1</accession>
    <name>A0AAD8XFD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_360417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364256.1">
        <property type="nucleotide sequence ID" value="XM_060502575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFD1"/>
    <dbReference type="GeneID" id="85386474"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="132" mass="13734" checksum="C2FDE0278795C4B6" modified="2024-05-29" version="1">MAPQQKQPERLKHVAAKANSSNPSQLGDPVSLKAEVSKLSPTEGDLGAAADSKSKSSSTAGTQSDGPAGAKNSDGSPVQDYDKRRLKDVAREDLESGNPSQLGDPVSLKAEVTKKDPAPGRADGQRVEKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFS3</accession>
    <name>A0AAD8XFS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_578183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364736.1">
        <property type="nucleotide sequence ID" value="XM_060505096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFS3"/>
    <dbReference type="GeneID" id="85388995"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF152">
        <property type="entry name" value="OXIDASE (CODA), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="61068" checksum="E4825EF49E5ED9DE" modified="2024-05-29" version="1">MSTTQLPVSDVDRYDYVIVGGGTAGCVIASRLAESLPQKRILLIEAGPSDFMDDRVLDLRKWLNLLGGELDYDYGTTEQPMGNSHIRHSRAKVLGGCSSHNTLISFRPFEYDLKIWQSMGAKGWTFHDFMRLMDKLRNTVQPVHARHQNELCLDWVNSCSSALNIPVLHNFNKHIAQDGALQQGVGFFSISYNPDDGRRSSASVAYIHPFLRGDEKRPNLTVLTNAWVSKLNIKGDTVTGVNLTLQDGSKRTITSKKETILAAGAVDTPRLMMLSGVGPKQQLSDLGIPVIHDLPGVGENLQDHPESIIMWELKKPVPPNKTTMDSDAGIFLRREAPNAGAKKTFFNPDGIPDGNIADVMMHCYQIPFTLNTGRLGYDEPKEGYAFCMTPNIPRPRSRGRLYLTSADPNVKPALDFRYFTDEEGYDAATLVYGMRAARKVAEQAPFKDWIAREVAPGPKVQTDEELSLYARRAAHTVYHPVGTTKMGDVRKDPLAVVDERLNIKGLKRVRICDAGIFPTIPTINPMLTVLGCAEKCAEMIIEEAQETARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFS4</accession>
    <name>A0AAD8XFS4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_753766</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363188.1">
        <property type="nucleotide sequence ID" value="XM_060514392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFS4"/>
    <dbReference type="GeneID" id="85398290"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="342"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="56947" checksum="0BD1B05A0171FECF" modified="2024-05-29" version="1">MSILDNYYLVVEPYLGHGNKTGDKQYLAHILESWSPDIDPDNDIGWALHWAIFQADDAAVQMMIDAGVDPNTRDKQDPGFTPLLAASQHGRLEMARLFWERVGPDGRFIPKKRGRSGPDCLQVAARNNHADLTAYFLGAWDGWDDQEMRRALLDAASAWCDDTVPLLLAHPGATYGPEVIQDALARAVGKRMILPERGTEPAPTTADATRQHQLVGCLIDAGGDPDGEDSRSHQPLIHATVHLHECIGGLSGLLEKGANPNRPDARQRTALHYVFSPLSRQPPNTTALQFLLLHGALPDLVDEAGETPLHAAAKAGTFPQLQLCLSHCRAPELESIQLRNSHGESLLHYAASGGQRTAVEYLLNSGLDANVASSNGWTPLLCVLSPTAGKTTHDMCFTAKFLLQNGASAGVVTDEGWTALHGLASWPAVQDPDLRAEVANLAKGLIESGSPIDVKSRVIRSPYTTSSTLYDVWGFRMRDFIQRAIPSAQDLGQADSTTPLAWARRCKSMDVVNVLSAHLASAGGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG28</accession>
    <name>A0AAD8XG28_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_583672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362230.1">
        <property type="nucleotide sequence ID" value="XM_060505683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG28"/>
    <dbReference type="GeneID" id="85389582"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="120"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="591" mass="67156" checksum="A30577921169500B" modified="2024-05-29" version="1" fragment="single">TIDQRHGFQSAYFGLSEESDPYLLRHYLYDDADEFPFLRVIYRRAQPWTPAHRDHSSVLGHHSSTHDENNVPVQFLLTSNELSDELRRLGPTNHSYDHGLVRKELNNLVSEDVGQRLVLLFVQYVYPALPVISRSQIVTALGGHFKSSSSGHASLPTYLLAAIYASALPFTAYDDILCVSSVYKKPPVQRLWQMAYDGVQTTLHTPQLATISGALLYLHKPRVGVQHVSADTSFAWSMITSVVGLATSLALHLDCSSWSIPPWEKRLRRRLWWMTFSEATWRSLLLGRPAVIAPDQWNVSELTFLDFEVEEPLLQLGDDMETNHFAEKLRHAINESDKSMVSQRLATLTIIADNIYRCLYTIRATERLADDLIGSIRAIKPLREELKLWYAGLPLYLKTPRLDPESAAPAAPSSAACLKFAYLTLEILLYRALLRPLGNIDLEDISNAVPQTEHVRSDSDANITEREPGEGLQNEIELIICAAENCARIVSTFTVELMSWDFAGFWYAWSRIGWAITSSFLALLVVQSPSVMHAKTCKNLIDKWRQILRHQSQSFEDMSLGILRLDAMYWSNMNKIFRINRHVAQVIREST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH77</accession>
    <name>A0AAD8XH77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_574984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366236.1">
        <property type="nucleotide sequence ID" value="XM_060504762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH77"/>
    <dbReference type="GeneID" id="85388661"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF4">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="55"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="443"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="675" mass="74850" checksum="BE436CD5F4CFC921" modified="2024-05-29" version="1">MAPGVLNSDGSMEDQNGQTAPTNGLAGTAAGRLHAIDPTVDTLTLLRSLPEPPIEAQVCVVGAGPAGLMLAANLGRFGIKVEVIDDRADQTPVGRADGLQPKTIETFRQMRLADPLLLRGVRVYDISFWRSTADEPLHRLGREVHYPPVIDVLDPYILLVHQGMVEGLFIDDLKKRGVEVRRNTAFESYSVPENKAGPLQVNCRTNVTQDRRTILTQYLVGCDGAHSKVRKSIPDARAIGLSQPAIWGVLDGELITDFPDIWSKTLVYSQEYGSILIIPRERNMTRFYIELKANPKADKRELGQEFVMARAKKIMAPFEVDWKYIEWFGRYQIGQRVASRFTDPHLRAFLAGDASHTHSPKSAQGMNTSMHDSWNIAWKLNLSIRGLAKQCLLESYEEERRKIAVDLVNFDYEHANQIAGGDAVALSENFKTNVRFISGIGAEYSESPLNRPDSQGLIMGDARPGCLLPPAKVTRYIDSNPVDIQLDIPMLGQFRIYLLMWDIQASSPFLETFCQSIASANSFISKLSASASASYAAQPRLPSSEDIYYRPERYTAVSHLFTFALITTMPKDDVEISDLPALLQDSRWTFYLDDIPEQDTRGQLCTNKWLGSLGPGEVSIVNVRPDGYVGSVGRWDSSMDDAGEEAARWLDEYYGGFLQLPGGASPTPTATPMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHC1</accession>
    <name>A0AAD8XHC1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division cycle protein 123</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364883.1">
        <property type="nucleotide sequence ID" value="XM_060514165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHC1"/>
    <dbReference type="GeneID" id="85398063"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27773" checksum="40025E17822AE4DE" modified="2024-05-29" version="1">MGRWMTPRIQECMLNPPTAIHHLTKDEVRQLLEISAELNYDIAKAEKSQTLSGLAAVMGQKTKSLETGTSAGYFIRTSHCSPKDADGGNLQPVNNMCEAVVKLASSKRTVQALLSLFYQLRQDADSPDNQLYFFPYYNDLDRLSEWRCYVKEGYIVAISQSRFYQPNHAGMTDEMLGRLAFQARRLWSRIAPDLNFKSCILDVYAEMLDPKFELKLIEINPWGAHSGSGSLLFHWLDDAGILDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG6</accession>
    <name>A0AAD8XHG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_570977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lysine N-acyltransferase MbtK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368214.1">
        <property type="nucleotide sequence ID" value="XM_060504365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG6"/>
    <dbReference type="GeneID" id="85388264"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000080">
        <property type="entry name" value="Siderophore biosynthesis acetylase AceI, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438:SF7">
        <property type="entry name" value="ACYLTRANSFERASE MBTK_IUCB-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31438">
        <property type="entry name" value="LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13523">
        <property type="entry name" value="Acetyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyltransferase MbtK/IucB-like conserved" evidence="2">
        <location>
            <begin position="277"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="466" mass="53002" checksum="0D40C725459CF40B" modified="2024-05-29" version="1">MSAPISLSAVSSSESIIKLPHPYHAEYAVQRAFNHDTFAGKTSEGGLHFYRLAPLAGQDNNTKKQTTPLPERLHSENLYFSEPADLKSSELPADSNNSAWARARRSPSTVFSWDGKTKPTLAQAWLLVYVIFILRPNEELVRLELRGASADVLGQQLRDVLLAIEHPTQTDAQKPAASAEQSTVVLLRSAFWQGAGSPFGPRPVWLPQESPAALDNPLSSYPLTPLQHTMTAVPASDPSNPNLYQQAWHPIRPAKPAPGATVYSRWIPHLKETFSMVALDYRNAEHLRLFHEWQNDPRVSQGWNETGTLDQHREYLRKIDEDPHQFAILAAWEDTFFAYFEVYWAKEDKLGGYYDAQDWDRGRHSLVGDVRFRGPHRVTAWWSSLMHFLYLDDPRTTWVVGEPKKTNDTVLMYDFMHGFGLDKFVDLPHKRSAFVRCSRERFFQLCPLGDNEKVVGGMRIQLVPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHP4</accession>
    <name>A0AAD8XHP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_720438</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363775.1">
        <property type="nucleotide sequence ID" value="XM_060512272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHP4"/>
    <dbReference type="GeneID" id="85396170"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="26126" checksum="286C427E657D30AB" modified="2024-05-29" version="1">MADRFPSLEDFDSGAQTDIKDTGAEPSTDDFLAREKALLGDDADQFATGDDAIAFGAGDDDLLGGGGSGNVISEESTFESQFPDLAQNEAVTGDIPGAGITAAPSVNYNSGYNAFVEEEEEPAVIREWREKRDAQNEKRAQQFAQQREETIKEARENIDDFYNNYNAKKEKGIAQTQKDAEKFLASREDTVSGGTSWERIAKLVDVSGKGSKGGASGSGKERFRELLISLKKDEKAPGASGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHP6</accession>
    <name>A0AAD8XHP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_790209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367717.1">
        <property type="nucleotide sequence ID" value="XM_060515707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHP6"/>
    <dbReference type="GeneID" id="85399605"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="79"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="182" mass="20378" checksum="049C9029A73BFD58" modified="2024-05-29" version="1" fragment="single">MSFQFPESHHRSQHSDPGPQRSNAKNSRSLSSAFFYRRTSRSTMTSTKEHPDYVEEPPHLEVPRVTWYKHAGLRSLYIRMPILMLCATINGYDGSLLNGLQTIENWRAYFNHPSGSTLGLFTAIVNIGGFSALFFSPYIADFYGRRIATAIGIIILVVGVIIQSVPSVNEGMFIGGRFLVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHZ0</accession>
    <name>A0AAD8XHZ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_624373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364060.1">
        <property type="nucleotide sequence ID" value="XM_060508438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHZ0"/>
    <dbReference type="GeneID" id="85392337"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="773" mass="84367" checksum="5196D9E1E6A9984A" modified="2024-05-29" version="1">MVVNVSTSVSPWRCDASPADDVHPQSAAPAFQQQHMSDPRYSREIFETCSIPVKIGNPHLAPKPSFATTMSKKKLPGKQIASSDSAGRKKSRRGRLSALFGHSPEQVGDAADDKNAPQDEATPTKATASNRRENRNHLQNSAATLKDDRKDNGTRDSVVSIVTTRSVTTEDKDAHESGAAASADKIDTIDFANKTQIRAISNPSPSRITKLPIHRHKRASSSFKIVDRDSADAVLLSASSYSPSPEKKNSAVAKPGTQASSSTQLPQYNQRYDQQAPLLPSSTYSGPTIHNSGPRNKHSQSKLKGNSHANHACALSSYTEPGPAIKITDTDEEIARKLEAMDFTPAVVSPPATPLLSALKTYVSDKSPGEKKVRFAAASSIKSGDSDIESGVSDDSDKTIKPGIGGMKAAPNSILSPTVWDKSAEPKIWVKNGKPTLFQPQKDPGYYTNPLWSRQYPEILSDDPRVNPYAASIAGSTTSTGGSQYSDTPTARAVTDFEVGNKLHSNGEPSTNVNFGTDAAPARTPFTRTTRGTMPSPPGANRNFVGRDFPEIPSVPAGFGMPPLYRGQIKLEIGGRRFVSSMDVLERSPWFKFIFSINFRDWYRDGVFHFDNDGDLFAHILRFLRTGMYPLFWDARNGFDYAMYATIQQQARYYMLYDLEAWIAQQKYHDVVETQVIHQKFIISNSQGWIHEQSLTGLDTSEISGVAEHPNVAFGGQSESEAPVADMFFSENGVNSKGKAKAIAPQQDGPEGAVALFTTEKVVKVHMDQLRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI16</accession>
    <name>A0AAD8XI16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">MICOS complex subunit MIC12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Altered inheritance of mitochondria protein 5, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Found in mitochondrial proteome protein 51</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_748902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MICOS complex subunit Mic12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368844.1">
        <property type="nucleotide sequence ID" value="XM_060513691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI16"/>
    <dbReference type="GeneID" id="85397589"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031463">
        <property type="entry name" value="Mic12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17050">
        <property type="entry name" value="AIM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="31128" checksum="E22F5C8E23545185" modified="2024-05-29" version="1">MGFTTGFTGGVTVTLGVAYLTVLAHQRNRESQSHTLRTQHHVLSSLLEPQIRIPPPLTRAEQAVKDRETLLTSAKDRWNREVENAVRWAQRTDWGEVREGLESGAARFWGGSIEKAGEVEQAVEKRAVPLVKEASAKGAAAAEASGAEVKKEARSAWERAREKSLAAEEAARARAAEAKKVLDAKAAEAKKIVDSKAAEVKAVVGDVVDKGRQQGEAVLVAAKQAVGVAEDKVSVKADGAVAPATTPVQKALHQRYEKPSGLTKSVKEVLAERYRKMDEQDNTQLRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIG8</accession>
    <name>A0AAD8XIG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_578348</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364675.1">
        <property type="nucleotide sequence ID" value="XM_060505114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIG8"/>
    <dbReference type="GeneID" id="85389013"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000220">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="39540" checksum="94CB13AA908166B7" modified="2024-05-29" version="1">MAAPQVHHLFHAPIADHSFSADRQTLAIARDSTIELYGPTGNSFKLKDELKGHDKTVTSVDIAPNSGRIVSCSQDRNALVWEPSPTGYKPTLVLLRISRAATFVRWSPSETKFAVGSGDRVIAVCYFEEENDWWVSKHLKKPIRSTITSVAWHPNSVLLAAGSTDAHARVLSSFIKGVDARPEPTAWGERLPFNTVCGEYLNNSAGWVHSVSFSPSGNALAFAAHDSSITVVYPSAPEQPPRAVVTITTQLLPFMSLLWSSEDEIIAAGYDCEAFRFKGGEGGWGLAGTLESKGRPGLSDAREESALNMFRQMDLKGKATDDTKLKTVHQNTVTTLRSYEESGGNLTKFTSSGVDGRIVIWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR1</accession>
    <name>A0AAD8XIR1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_752256</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364930.1">
        <property type="nucleotide sequence ID" value="XM_060514173.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398071"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="2"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="1004"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2504"/>
            <end position="2581"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1004"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1155"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1036"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2589" mass="282430" checksum="B4F2C14F827CFFF5" modified="2024-05-29" version="1">MGDPIAIVGLSARLPGDGDTPEQFYESLLAGRSARTEVPRERYNAEAFWHPDADRSGATRVRHGHFLQGSISAFDAPFFSITPTEARSIDPQQRGMLESVYKALENAGIPLDTVAGTQTGVYVGCFTADYNDHIAKDLDIPNKYSALGTVASMLSNRVSWFFDFRGPSVTVDTACSSSLVAVHEACMSLKLREVNMAVVGGCNLILTPEMTLKLDAAGVLGPDGKSYSFDHRANGYSRGEGFGALVLKRVSDAIRDGDVIRAVIRNSSTNQDGRSPGITQPTKRGQVALIKHVYERANLDPSLTRFAEAHGTGTPVGDPIEASALAEIFAPHRSADEPLYVGALKSNVGHLEGAAGVAAVIKGVLTLESGVIPGNIWFEKRNPKIQDAWNLRFPTKPTAWPQRGLRRMSVNSFGVGGSNAHVVMDDALHFLKSFRLVGNHRTETIPKIPRQLDAPLANGTGRVNGFHRPSDSGIHLDDFDTEDAPRLFVLSANDQDAVSRLRDGYRDYLATKAAQIVGESAQLRFLRDLSYTLACRRTRHSWRTFSIASSPAQLEKSLEGNAATPIRAKTNPRLAFVFTGQGAQWATMGMDLLAYRAFQESLLAADRYLNDLGCNWSLTFELSKSKTSSRINDPEFCQPICTALQVAMVDLLSTWEVYPHAITGHSSGEVAAAYAAGAISRQAAWKIAYFRGKLSAKLARSASRPSTGMAAVGLSKAATQDAIDRVNHQLGGEGTLEIACMNSADSHTVSGDAEKIDALVQLLSAEKVFARKLNVEIAYHSQYMRAMADEYLVAMGDLQQGTLRSSVKPRFYSSTMGVPILPSQLRRPEYWVKNLVSPVRFTESVTEMLKGSKTPKINGHINGHINGLVNGNVNGHVNGGVNGDCDEELPFEPITDFLEIGPHSALKGPLFSTVKQVRGNAKVDYHSLLVRQKPGVETALESVGTLFCHGYNVNLAQVNDADEPHGPKPLMLTNLPAYPFDHSKEYWVNSTLSDDFRKRPVSRHELLGAPMAGFNENNAVWRNYIRLSENPWIEDHKVSGDVLYPAAGMLVMAIEASRQIADKSKALKGFRLRDVSFKLALRVPNDANGVGSQFYLRQHRENSHSTVSTWREFQLWTLQDGAWREHCHGFVQTEYEADDQLALRRSEESVHDGCATEVSVDKLYRSFAESGLNFGPTFQTLSDVRLGRDLNMVATLHPPLEKIKKLMPHQYVQPHLVHPATLDGVVHANLVALISSSEYAGATRVPTYLTDGWISAQSSLSHNSYSVSAESRVKGRSEVVSDVKASHLEQGDEMVRMSGLVFKTISSGPSKETSQGVLHPAFNISWKPDPSFLTKQQASQLFQLPLTQEDDPSTWMLDCEALCLAYMRRCVESLTQGSIGKMTWYHQRYVKWFQHVARQHSDGPASESIEDLEAKVLAGNASEGKLIIAVGQALSGILTGDRDPLDVIFKDKLAEDVYSNGLGSKRCYTQLCSYLDIMAHKNPNMEILEIGAGTGGATRPAIATLTRDSGRRYGHYDFTDISPSFFEQAKETFKDEVGRMGFRVLNVENDPVSQGFEAGKYDLIIAANVLHATKKIDDTLVNARKLLKPGGKLLLFEITNTEILLGSFCFGTLHGWWLSEDKDRIWGPLMSPNSWDTHLRASGFSGLDAVFDDFASSPHQMSSILVSSNPPSEAVACSPTSYYILTKESPAQIALAAKISQSIGQGGDCQIATLTSLADKSLADVTCVVLSELGHSTLKDMDDETFNGFKRVLTQSKNILWATRGGTSTAPDPDSELVTGLARVVRSERPDVNFVTLSFEQDATEEFAAAKCAQVLGAARDSVENSFRVIDDVVYVSRLVQADYMTDHIQNQTGVVSVENKLLKDEAYRSLCLQVGDVGQLDSLRFEEDALTETLLGDHDVELKTMACGVSIGDVSSVLGKAEELPLGLEASGIVTKSGPASRFQVGDRVFGLAVSGTMKTHVRSTDGLLAKLPDGVSFTDGAVLPVDYTTAYAVLCEVGSIREGDSVMVHGGCSSIGKAFGQVAQLQGAEVYTTVTNQSERDELVKQCNIPEDHIFSSRDLSMRSTQQKLVKGRGINVLVTVTDDLVDGVIDCIAPFGRIVYIGSGAGISNTRVPRGRNIRLESFDLTSCLAFDLSRTETMFQHMVDIVFANWNNISRPSPTTIYSFSQVGDAFRRMQSEDQDTAKVVLEPRGDDMIPVVPSRKSLSRFDPQASYVIAGGLGGLGRSVARWMASRGAKNLILLSRRGAVEKAAIELVAELKPVCDNVVTPACDVTDAKALQTVMAELAESLPPIKGCIQGSMVLQDNLLKNMSLDNWKAAVQPKVQASWNLYNALGDKMDFFVFLSSTVGVTGSPEQANYAAGGTFQDAFAHHLVSKGVNAVSIDLPIIHGVGFVAEKPELWDYLSSAGWTHITADELYAVLDYHCHPASASASQETARAQVIPRLWLPQETAAEGYQTQTWGEDPLFSHLRLTETDDAGKGDDANKDINHKAHLQCASSLEEAEKIVLDALLLKIARMLSIDALNLETSKPLHAYGIDSLTAVELRSWLMKELGAEVSVFDITNNSSIAQLAMLATKKSSLRQRFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ46</accession>
    <name>A0AAD8XJ46_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_299819</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365620.1">
        <property type="nucleotide sequence ID" value="XM_060502245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ46"/>
    <dbReference type="GeneID" id="85386144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000022">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="12">
        <location>
            <begin position="349"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="14">
        <location>
            <begin position="622"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="13">
        <location>
            <begin position="850"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR003354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1725565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1214" mass="135504" checksum="6D9BDCF04A69C0B8" modified="2024-05-29" version="1">MQASSGMLTKFESKSSRAKGIAFHPKRPWILVALHSSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHKTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFHHELPWILSASDDQTIRIWNWQNRSLICTMTGHNHYAMCAQFHPKEDLVVSASLDQSVRVWDISGLRKKHSAPTSMTFEDQVARANQNQTDMFGNTDAVVKFVLEGHDRGVNWVAFHPTMPLIVSAGDDRLVKLWRMSETKAWEVDTCRGHFQNASGCLFHPHQDLILSVGEDKTIRVWDLNKRTAVQSFKRENDRFWVIAAHPEINLFAAGHDNGVMVFKLERERPASSVYQNNLFYITKEKHVRSYDFQKSTESPTLLSLKKLGSPWTPPRTLSYNPAERSVLVTSPSDSGSYELINLPRDGSGAIEPTESKRGQGNSAIFVARNRFAVLNTSSQTIDIKDLSNNTTRSFKPPVGTSDIYFGGTGNLLIITPTAVHLYDIGQKKSVAELAVNGVKYVVWSNDGLYAALLSKHNVTIVTKTLEQVSTLHETIRIKSATWDDAGVLLYSTLNHIKYTLLNGDNGIVRTLDQTVYLVRVKGRNVYCLDRAAKPKVLHVDPTEYRFKLALVKRNYEEMLHIIQNSSLVGQSIISYLQKKGYPEIALQFVQDPATRFELAIECGNLDVAVETAKELDRPKLWQRLSAEALAHGNHQVVEMAYQKLKQFDKLSFLYLSTGDHSKLARMAKIAEHRGDFTARFQNALYLGEVEDRIQMFKEIDLYPLAYMTAKSHGLEEECQAILEATGLTEDQLETPTIGEALTPPKPVVPTFKANWPTKATSQSVFEKALLGQVEGLSLEDTPAAANGFDDDVEEDAAAKKNGNLIDVDDDEDAAGWDLGDDVVPEIEGDFVNVDSADAGGAGSSEADLWARNSPLAVDHVAGGSFESAMQLLNRQVGAVNFAPLKPRFLEVYQASKTYLPASANLPPLVNYVRRTIDETDPRKVLPIVPRDLEFLATNDLQQGYNSMKTNKLEDGLQIFKGILHAILINAVSSESEVAEAKKLITSASEYAVAMEIELSRRKLGTTGEQLKRNLELSAYFTIPKIEVPHRQLALHNAMQLAIRNKNYGSALSFANRIIANGGSSKLTENAKKAKAQCERNPSDAIEIEFDQFAEFDICAASHSPIYSGTSYEECAFDGSKYHSKYKGTVCKVCGVCEVGKHGSGLKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL20</accession>
    <name>A0AAD8XL20_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_568732</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369406.1">
        <property type="nucleotide sequence ID" value="XM_060504113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL20"/>
    <dbReference type="GeneID" id="85388012"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF9">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102440" evidence="2">
        <location>
            <begin position="20"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="3">
        <location>
            <begin position="130"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40514" checksum="D95A394520161CB9" modified="2024-05-29" version="1">MHPAVLLVLTSALLGTAHPGHHEETHPSLLASRHAHHGLARRGLEACSSSKVYRDLQARALVRRADAIAYHRAVRKRATDSAGVGHNLTSSHVGIDTSAASADLFGSNHTCILDPEGEIGPFWVKGEHLRSDLRDDQEGVDVVLDGQFIDVETCEPITDLYWDLWNCNATGVYSGVQSSMNGDVNDASNLDKAFLRGIQKTDADGVVQFTTKFPGHYDGRATHHHMVAFLDATVLPNNTLSSSHAAHIGQLFWDQDLITEVESLYPYTLNTVDVTLNADDHVVTSQLGSNADSDPFFDYAYLGDDVADGLFGWITIGVNRSASYETSYDFELTEAGGVAVEGESDGGLSGDMPSGGMPSGTGAFSGGAPAASATAAATAACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL82</accession>
    <name>A0AAD8XL82_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_605037</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369472.1">
        <property type="nucleotide sequence ID" value="XM_060507310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL82"/>
    <dbReference type="GeneID" id="85391209"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="122"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="15">
        <location>
            <begin position="453"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="304"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="771"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1729417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="787" mass="88435" checksum="65EC53061E486398" modified="2024-05-29" version="1">MASILEPVGFKSMLNNVHDVWQQVRIPVILFTAFGLLILRFYLHSTEEKSELKALPKAYNREKPETKPVEEEKKDVKPSPPNPTVESKAPKPNGPKRIKGGIVKRTSSNDAKGEALVRKVRPLVFFSSITANTPKIAKEYAEGLEKELQKVAAETDCSFMTPEVLDLAEVDFDDYFITPPKSEEDPADLFYLFLLPSYNIDTINDTFLEHLQETHHDFRIDTAPLSSLLGYSVFGFGDREGWPTEEDGFCFQAKQVDKWMAKLTGRKRAFPVGMGDTKRDYTERLSEWSEGVVDVLGMLAKTGSLGEGLPGSGAPEESDDESAAEDDDEVLIEDSEAKPEKLKSRKNIDDVEDLGRIMKSSNPDAATNGSAAKSATAGSAAPIAVDFTTYGKTVAKKTPLNAAKEMVPKNSPTYASLTKQGYSIVGSHSGVKICRWTKSALRGRGSCYKYSFYGINSHQCMETTPSLSCSNKCVFCWRHGTNPVGTTWRWVVDPPELIFDGVKANHYNKIKMLRGVPGVRAERFAEAMRIRHCALSLVGEPIFYPYINEFLGMLHAERISSFLVCNAQHPDQLAALKAVTQLYVSIDASNKESLRKIDRPLHRDFWERFQRCLDILREKRFKHRTVFRLTLVKGFNVDDEVEGYAQLVEKGLPCFVEIKGVTYCGTSTASNAGLSMSNVPFYWEVQEFVTALEKRLNEKGLKYGIAAEHAHSCCVLLASDRFYKDGKWHPRIDYQRFFELLEERGADGDWKPEDYMGEATPEWATWGKGGFDPRDDRVDRKGRKIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLM9</accession>
    <name>A0AAD8XLM9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">von Willebrand factor type A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_12139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369659.1">
        <property type="nucleotide sequence ID" value="XM_060501151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLM9"/>
    <dbReference type="GeneID" id="85385050"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000014">
        <property type="entry name" value="von Willebrand and RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="312"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="503"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="876"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="918"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1040" mass="113869" checksum="516C49637E30172A" modified="2024-05-29" version="1">MASGAGRNRRERTFVGSECAVCEEPLEHTLRGERILQFSCSHVSHEACFYEFIREFESQYCPSCDAPLHLDTSRGGNVLDIEKISNLVRSVSSTETRSNHTPTPTATPWDNPTPTPRPTSIESNQRNMASTHTRESAPRSTGRDRESSQPPASERYGPSRHARSDSEATGVASSGGYPETTQSGPPRRHDYDVQAMETTPGSPRAITRNPIPAPTVTVRSEFPTINRSRQQQTLTCLITVEVPDNKWRPDPEDLGSAPPGPPAVNARIDEAFARPPSPARSAPRFYPYESREVLEEQTENLRNRVDNWHGLDFSRFGKLRLYGTLRVGKDKASWQELECFLFAEMLICVKEKKVALAGQWDENGMPKKTTRCTLKGSILIKKHLNEVSETGNIDENILTLNLSVAELPQFHLRFENRNQLKLWHQALLDLNAVETSPVRSPEYDRGEFSETDEDDWQRGSRQQRVSSIASSWGGPKSTTTAPTEYTNFQRSPTMPASIHVPIDVVVVVPISSSMQGVKINLVRDALKFMVNTLGERDRMGLVTFGSGGGGVPIVGMTTKAWPGWGNVLGSIKPVGQKSHRADVVEGANVAMDLLMQRKYNNPIATIMLISDASTSDADSVDFVVSRAEAAKITIHSFGLGMTHKPDTMIELSTRTKASYTYVKDWMMLRECLAGCLGAMQTLSHQNVKLKLKLPEGSPAKFHKISGALQITKRATGRDAEASLGDLRFGDKRDVLVQLVIVPDNTSQEQLPQDPWDNIVSGLEALGGAGDGDDQRVTSVEEVPLIQADLTWGDILRDGTLSHLPRPSLLAITMLPAQAKNKNSWAGSPPIPPHPHIVQRRMELLTSDMLTRALTLVSRGQHDRAHTLLNETRSILKGLGKGGLPPIPPPTAPPTRSLPSTPHPGNDASPSITPDRKQTPSPTQSANSSAVNGYQATGIGRSRSNDGLGLGAGIDANTVAALDHELESSLEWISHPAVFGRDSRKAVLQAIGVISSQRAFTFRTPIESLWSGRVAGVKKLTSKSREWREEGGGEGGIMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLS7</accession>
    <name>A0AAD8XLS7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_738039</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369825.1">
        <property type="nucleotide sequence ID" value="XM_060513019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLS7"/>
    <dbReference type="GeneID" id="85396917"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1170">
        <property type="entry name" value="glycoside hydrolase family 81 endo-[beta] glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="9">
        <location>
            <begin position="44"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="10">
        <location>
            <begin position="369"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="748" mass="81456" checksum="B7AD4F7865D2CCCC" modified="2024-05-29" version="1">MDMNSDLSSPGSEIDGEVARGGSDNVFVKISHDRPILVPSRADHPQKPVGVDNIDNPIQTNKFYANFFANNQDNATWTHPYSVWWSNDTVEQGHGLSISHTDRRNFIYGPGEPVQSFEDPFFDQSLALSARELQNGTVLTTDTLTAFSANVNLATRKGAKPIVSFPVVQGMAFVTGIYNDATILIQSQKHFSNITDLRLSSNGLGATLYGWDARLGDGSSWLIYLNPTSTFERPTLRMTDKGTILGPRQFTGTVQVAKNPAGKAGIDIFSKAAGAYPVGATLSGSVSGKTGTYTLAWEKKGLKERSLLMFALPHHTARGLTNITLASTTKGIATAMLADEFTMLPTDMGFDPWSPRLGSVGSAGSAATVSEDAKAAIISAAKVELARDITTLTNLTSKYYAGIAFSVYARAIYAVNNIAGDTSFTASSLTKLEAAFDKYVNNQEPNPLFYDDVWKGLVSSGSYGNNDSSIDFGNTYYNDHNFHYGYYVYAAAIIAHFNPSWLTKNDGLNKIWVNNLIRDWSNPSTEDPFFPFSRNFDWFHGHSWARGVLEAPDGKDQESSAEDAFSTYAIKMWGKVIGDAKLEGRGNLQLAVTARSLQSYFLMASDNDVQPPNFIGNRATGILWDRKINHTTYFGDEIAYIQGIHMLPIVPSSAYIRKASFVREEWDQYFAGNKSGSLTSGGFAGHVYANLAIADKAGAVESYEFMKKQTPDSPYLSGVSLTWNLAYTAALGGSLGSNSTLNSTSRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM15</accession>
    <name>A0AAD8XM15_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_567459</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369862.1">
        <property type="nucleotide sequence ID" value="XM_060503959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM15"/>
    <dbReference type="GeneID" id="85387858"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="46"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27596" checksum="55012E85739C74B6" modified="2024-05-29" version="1">MASQESKSASGSGPTQCVGPLYRSESQKPTATVSTEIKLDNVVVLSQTPQLIALLTIIRDKNTERGDFIFYSNRIIRLLVEEGLNHLPTVEHDVTTPIGRTYSGLMFQGKICGVSIMRAGEAMEQGLRDCCRSVRIGKILIQRDEETAQPKLFYDKLPEDIAQRWVLLLDPMFATGGSAIMAVQVLKARGVPEDRILFLNLIASPEGIQNFTAKFPKLRVVTAFVDQGLDEKNYIIPGLGDFGDRFYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMF2</accession>
    <name>A0AAD8XMF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370182.1">
        <property type="nucleotide sequence ID" value="XM_060513499.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397397"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1624"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="641"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="684"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="781"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1441"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1561"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1758"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1882"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1373"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1441"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1780"/>
            <end position="1793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1888"/>
            <end position="1906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1907"/>
            <end position="1917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1926" mass="209217" checksum="2EC91C1BF5A95502" modified="2024-05-29" version="1">MATSLAADKPHLPPVEADMNDPFVSPPGPAHNRYSTYDSQSFSSSPGQAKRALQAHIADTERRLDEAGKLGTALVHQRKELAERLKEVEEQETEGELAPELRAKLADIEKEYNDVARETARAFLPKQRVPSNEAAGGSPYVPDGRIGRRSVSPSKFEKLEIQATGSPSKLSVPNRKVRNQPANRIHDIEFAAEISTSLIAQVRNLQSLLSEKDEELRDIKVDKSKLEIENENFQQRVKTLDESENRYKDENWNLETQIHDLIASQKDAADREKKLTQSLNVLQAEKNSAQKELDDAKVSLAKLAEEHERAVKHLDLDLTTAKRNAATAETERNALRRKVDDLMSQNTELAKAISVQRGRMSDRDFVRGVSDEDFETATDGFTPEHSPPPSPIKGTPRHAMLESETLKSSLLHAQRTIQSQKTVIHREKTEKLELKRLLQDTRDELEKLRTDAAPAPARRTRKVESREFKKPSRGLLGGHRSSRNEVYQDDNEWEEATEIGSPRTSPTIRSNSTVRRPGSRPGSSYRPQFTDVSDAFETANETSDAAFETANERGTETEDFQTGVEDFSGGDDTETETESPSKGRELRPQTLVMGGGRNSYDSTASTSADEDEEYIEYRTPTSQYNNQRMRVRLGRGLMNRRSRQVSEEPNFQSSPASAATGSATGTPQPTEGQSLFAELGELENSDAESIEETPSRARSATADSTSTPAVPTLSHDSVNTGSMTDPIKRAAAASRPLMVDSGMMTEPMIESPPLSPVSVVHDEKAESLGSMMAAGQVARHLSQDDATDGVRSRPLSTLSYSDSGAQYDRDMEAKLAQFPMPPSSPQHFVLPPPPELSLSFIDAQDIEPIVEPVTPPPAPAPLTMTSLVSEIVEPVAEPEVPAPVLAFTPLVSEIVEPKAELPILPPTLSISTYLSEAVEPVAEPEVPPPALSLSALHAHNLEPVAEPEIPPPTLSLSALHAHNLEPVAEPETPLPALSLSALHAHNLEPVAEPEVPPPALSLSALHAHNLEPVAEPEVVIPVPDLTLSALLSEHIEPKEEPETSRSLAAIPAPIPVPISAPAPTLTLSSIASENVEPREEPEVPVVVPTLSLSAIATEHVEPKAEPEVVPLAPTLSLSALYSHNLEPRAEPEALPPALSLSSIVAEDVEPKAEPEIIPEVPALSFSSIAAENIEPKAEPEVVVPAPVLGLTSISSENIEPKAEPAPALTMSSISFANIEPIAEPAVLPPLPPALTLSSISSENIEPKAEPEIPAPPPALLAYSTISSEHVEPRAAPQPVLDFSSVLSQHVEPAMAPETVAPKPNFGFSTIESIETQPISPRSPKRDAFILPRDMDSPFDEKDAPRTPSKNALMSSVFGRGKNKASDSLIIAEDDTRQSPTDERLSETPESQRPFKEISTNATGRPAPKVIVPMSDSGAQTSLTADAIDEMLLAKTKATSDKSLSSFGTPSTPGTVRIRRPSHDSLSSFSTENKMDTAFRRPGSANSNLAPTQPLPPLPPNHKEAIEAARTGSSHSAVMGPPLWPASAMRNQRPQTPNGAARPQSPLSISTSMKATPVARGTRAGSAYGTAEVHSPTKLSTMSRHSSVSSFVSEIDHRFNPQAELAAATGFGPNTDPRMIQAITQTMIGEYLWKYTRKAGRGEMSDNRHRRYFWVHPYTRTLYWSDRDPATAGRSELRGKSVPIEAVRVVTDDNPMPPGLHRKSLIVISPGRTIKFTCTTGQRHETWFNALSYLLLRTTDEGQSDVEEMAGAITQADVDEFNPQFGRRTNSTARPRPPPSLSSYNSRTTRNQSPAVDMSMNVPTLTPNKHSIAQAQRPTMAGRISGYFGTFSSLRSRSAAAPTPSIYEASEVHDSAEDLREIIERQDRDADRLENVRACCDGKHDVGTLHHHPKRGRPSGAHSHSHSHSQSGPSTSATPMSTVRARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM0</accession>
    <name>A0AAD8XMM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_783786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370134.1">
        <property type="nucleotide sequence ID" value="XM_060515596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMM0"/>
    <dbReference type="GeneID" id="85399494"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042029560" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="115" mass="12507" checksum="A76171B657617951" modified="2024-05-29" version="1">MKMQLSSMLILGLGLASTTSGYVLTLYKGENCGGASQRRNVYDNTCATTDFAPKSVRVEVYGGYNQKAYFYSTKGCIAGQELRGPWYADNENNSWKRGACISMGGMTVNAFGSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM5</accession>
    <name>A0AAD8XMM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_602071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370302.1">
        <property type="nucleotide sequence ID" value="XM_060507144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMM5"/>
    <dbReference type="GeneID" id="85391043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="560" mass="63800" checksum="ABAF236F0CBE2E67" modified="2024-05-29" version="1">MRLINVNTLQLEEFFDDETSHYTILSHTWERDEVTFQDLCWLHEYEENIEAFASVEALMASATMNSAKKAKDLRQRSGFHKIVQSARLTKEHLLQYVWVDTCCIDKSSSAELSEAINSMFRWYQEARICFVFLSDFQPSDVTNAPLDFAQCRWFTRGWTLQELLAPRHMYFYNQEWKLVGDKDSLRYEMSEITGIPRAILAHDHSFQDVCLAQRMSWASRRQTSRKEDMAYCLLGLFDINIPLLYGEGDMAFVRLQQEIIKETTDQSLLASWGLGNSLSTRGHFFATSPAAMTRAASFYTDNITEMSSSEFRMTNRGFRINLSLLLLSEFESGSHNAPNCYYALLNALDDQDRRICLPLFLNNSPSGDEFVRSPSGPVALSETSLNSLGEATYEELVIVREPSWERPLAAGAWQISITNPPVSDYLFAPPINIVETFPPMMSSKHEKGTFTTVIAMPPPANVPGSPHDKPWQFFLRCSYPDPAGERDFALVFDLPSRQGAPRGPLQPYVIDWRKFHSVLRKDDEGMSQEGPYTSLADAILSGARFHGLEYAEKQARSKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMZ8</accession>
    <name>A0AAD8XMZ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_601186</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370500.1">
        <property type="nucleotide sequence ID" value="XM_060507080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMZ8"/>
    <dbReference type="GeneID" id="85390979"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="578"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="644"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="789"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="863" mass="98747" checksum="0149337E50B304CE" modified="2024-05-29" version="1">MAPAQDTMFRSANMSMVQLYISNEIGREVVTALGELGLLQFRDLNGDVSAFQRTFTQEIRRLDNVERQLRYFYAQMEKAGIPLRKFDVDAERLANPSTSEIDELAERSQSLEQRVFQLNDSYETLKKREVELTEWRWVLREAGGFFDRAHGSVEEIRASTDNDDAPLLQDVEQHNSAPEVERSFSGMNIGFVAGVINRDRVASFERILWRTLRGNLYMNQSEIPEPLVDPTNNEEINKNVFVIFAHGKEILAKIRKISESMGAEVYNVDENSDLRRDQIHEVNARLNDVQNVLRNTQQTLNAELTQISQALSAWMVLVTKEKAVYNTLNNFSYDRARRTLIAEGWCPTNDLPLIRSTLQNVTNQAGLSVPSIINEIRTNKTPPTYIKTNKFTEAFQTIVNAYGTPTYQEVNPALPVIVTFPFLFAVMFGDFGHAVIMVSAALAMIYWEKPLKKVTFELFAMLYYGRYIALVMGLFSLFTGLIYNDVFSKSLTLFDSAWKWDVPDDYKPPQTLTGKLNDHGYRYPFGLDWRWHETDNDLLFSNSYKMKMSIVLGWAHMTYSLIFAYVNAKHFKKPVDIWGNFVPGMIFFQSIFGYLVMCILYKWSVNWSDPQNPRNPPGLLNMLIYMFLQPGKLEEGAQLYPGQATVQVFLLLLAVIQVPILLFLKPFWLRWEHNHARAKGYRGIGESSRVSALDGDDDEDHGLNGRPSFESDGEGVAMITQDLHGDGEHEEFEFSEVMIHQIIHTIEFCLNCVSHTASYLRLWALSLAHQQLSSVLWSMTLGPALGFSGIFGSIAIVVVFYMWFFLTIAILVMMEGTSAMLHSLRLAWVESFSKFAEFAGWAFQPFSFTTTLEESEELKEYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP81</accession>
    <name>A0AAD8XP81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aft1 HRA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_295313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371108.1">
        <property type="nucleotide sequence ID" value="XM_060502215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP81"/>
    <dbReference type="GeneID" id="85386114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000053">
        <property type="entry name" value="BZIP transcription factor AtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021755">
        <property type="entry name" value="TF_Aft1_HRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021756">
        <property type="entry name" value="TF_Aft1_HRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020956">
        <property type="entry name" value="TF_Aft1_OSM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11786">
        <property type="entry name" value="Aft1_HRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11787">
        <property type="entry name" value="Aft1_HRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11785">
        <property type="entry name" value="Aft1_OSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="424"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="449"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="56362" checksum="238647785CB228F8" modified="2024-05-29" version="1">MGTSPNDASTGGDTKSPKQSNNATPPRQNTIPEVKQPDPSLKPDADGAKPLGPPPRPGQTTGNTPDYFGAGAASLSLEPNPFEQSFGGGAPETPGGTKLPSVAALTSPSSLLPGSGATPFNWGGGSLRTGPLSPAMLSGPTSDYFSDTHHLRGGFPTPNESSLRTGLTPGGSGSMFPAPSPNSQQLFAQLASGGATPSTIDFHRTALSAAAKRDTQAQNQNQNQNQTQPQNQTQNHNQQQTAVTSQPQEMPNGASAVKTEAKQFDPHDNDAANGLFMLAQGAQGRNGAPNGGFAATQAQAQAHPPPPPAQGVNTSPQMSANGAGSVGAGSSVRGVSEGGSAMSDESEQARPAARGKGKRNSTGGASTNGRRKAEEPPAKAPPAKKSKPNNNIPPPDMMGDDSQSDDDDMKHENGEGGKSKMTDEEKRKNFLERNRVAALKCRQRKKQWLANLQSKVELFSSENDALTAQITQLREEVVNLKTLLLAHKDCPVTQQQGLHGAFMQQAMEPFNPQMNPYGMAAPIPNQQVLAAGQGVQRRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPE6</accession>
    <name>A0AAD8XPE6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_646439</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8 9">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371062.1">
        <property type="nucleotide sequence ID" value="XM_060509964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPE6"/>
    <dbReference type="GeneID" id="85393863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 9 10" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="135"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="267"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="395" mass="42726" checksum="F69FBE7A5C0BF529" modified="2024-05-29" version="1">MSGMFKSPFGANANPFGGPTDGPPAGGNAIHRVIEEEENDTITSPTSPNFGLNTGMTFNGPFGGDAADDAPPSALRSPPNPESYPAQYNFGRRTSVSAESLKPSADTYDNWSPPYHEKTKEQLGRLQTAIEGNFLFSHLDEEQSGQILGALNEKPIPAKDIKVISQGDAGDFFYVVEKGSFDVYVNNSGTLQPGPEGMGQKVGTIQAGGSFGELALMYNAPRAATVISAESGCTLWALDRLTFRRILMESTFARRRMYESFLEEVPLLQSLTPYERSKIADALETQKYAPGEIIIKEGDPGHAFFLLESGEADAYKDGVKESVKHYSKGDFFGELALLNDAPRAASIVATTDVKVASLGKNAFQRLLGPVEGIMRRTKYEEVKTGVEEMDPLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ08</accession>
    <name>A0AAD8XQ08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371441.1">
        <property type="nucleotide sequence ID" value="XM_060513317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ08"/>
    <dbReference type="GeneID" id="85397215"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="13420" checksum="FED600F7CC14E3C2" modified="2024-05-29" version="1">MVETGSVAGSPPEGQTDLSSHDHSIGRRMNNYPALSWLTEAFLQTQDRSARIAVGSPRSGVGILGLGLLEHHINLLPTMRHADAVPIFDHAAYGGARYLGWRQKVATWPLSQQEAMNNRSFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQL0</accession>
    <name>A0AAD8XQL0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_715008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371626.1">
        <property type="nucleotide sequence ID" value="XM_060511701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQL0"/>
    <dbReference type="GeneID" id="85395599"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000289">
        <property type="entry name" value="Acetyl-coenzyme A transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="573" mass="63758" checksum="D0378ACBBDDF6778" modified="2024-05-29" version="1">MSVRTRRNKSVKRKALADLAVDTDGTNGHANGAMNQNNVEFRRKATTPGSDTVTANLMSRESFTLDDPVPKTPIANNHGFFELPLQDQRNFLLLVLLYFLQGVPMGLAGGSVPFLMKDHMSYSEIGIFSLASYPYSLKLLWSPIVDAVWSPKVGRRKSWILPIQLLSGLGMLWLGSTVENMMANTGKPGGPTVWNFTGWWFFLVFMCATQDIAVDGWALTLLTPGNVSYASTAQTVGLTAGHFLSYTVFLAFNSKDFANRYFRSSPLDHGLMSLGGYLTFWGWAYIAITIGLSLFKREERTKNEDGIWDVYKIMWGVLKLKNIQTIIIVHLIAKIGFQANDAVTNLKLIDKGFGQENMALTVLIDFPFEIALGYYAGKWSQEYTPMRLWCWGFMGRLVAALIAQFTVTIFPAGGVTPWYMLVVIGEHVFSTFTNTVMFVAVSAFHARIADPVIGGTYMTLLATVCNLGGTFPRFFVLRLVDYFTVATCKPGNPADLNALKGPVITDPFSCSLQPDKEKCVNGGGTCEMVRDGYYFVNIICVVFGVVTFMLYIRPRVLHLQSLPMRAWRLAPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQM2</accession>
    <name>A0AAD8XQM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_746141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371770.1">
        <property type="nucleotide sequence ID" value="XM_060513214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQM2"/>
    <dbReference type="GeneID" id="85397112"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="530"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="554" mass="57149" checksum="E695506DC72E6D68" modified="2024-05-29" version="1">MEIEVDEDLLRTVATGGEMDYGLWPALSQGIISRLDKIAHNEFPIPNLPTPPQPINAPGQQPRLLSPLPSSSIDPASSQPSSQDADKENSQPKDASPSKATVESATDADATPATTSGSLPAQIEAMLNEINTVLASFPKYPPHTIQRLAELVLEPRRHYRHLASYLHAVDRVVHVTSGANTYPLPPAIPDMSTMTLLSNGSANGQEVNNPAASVAWSNSTNSVASTVGTDEALGGALLTPIPWLTRRPSPGSSSPASSNGGGPAEIRTESTETIDGPNGVGSIETVSVSVNGIPSMGASSSRAITQGELLRQEQEQGVVPVNQLVRQAEEAQHAAALRSGDGGRASSPEKQQQDDEQQDAAGAAAAAEDENEAPHARGPEEIGVGDLGPQSETTSFVGGGPGLDMQGIDVEAAVGRKAATPPPEDVKEGDAATEDGTTADAVVDDAASDTSVTSHPKRDADEELDGLASKKVKEHEGDVAGEATDATVPTSPKVDDTKEDDAKKDEPDVAKTEEGKDEETETKKDDATDEAAAVAAAAAAKAKDAEMAAKAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX3</accession>
    <name>A0AAD8XQX3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <ecNumber evidence="5">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_597015</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371920.1">
        <property type="nucleotide sequence ID" value="XM_060506881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX3"/>
    <dbReference type="GeneID" id="85390780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004754">
        <property type="term" value="F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000217">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000627">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9 15" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="18">
        <location>
            <begin position="50"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="17">
        <location>
            <begin position="216"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="357"/>
            <end position="360"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1731865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="415" mass="45829" checksum="148AA9D254B57FE3" modified="2024-05-29" version="1">MFLESLPHTQLSSSSTFPHRTFIASSPTTAINCGRKSSIQVANMAHTILHLRSETKPLEHRSALTPTTTRKLIEAGYEVRVERSPVRIFDDAEFEAAGATLVPEYSWESAPSDVIIVGLKELEEKEFPLKHVHVTFLHVYKNQGGWEKTLSRFPRGGGTLLDLEFLANESGRRVAAFGFHAGFSGAALALENWAWQLTHPGEPFPAVEAYPNEDALIVDVKKALDEGIAKAGRKPRVIVIGALGRCGSGAVEMAKRAGVEDIVRWDMEETKNPGPYKEITDADIFVNCIYLSQPIPPFLNRESLQVPGRNLSVICDVSADTTNPHNPIPVYTVATTFDKPTVPVEGLENPPLSVISIDHLPSLLPRESSEAFSNDLLPTLLNLKDWRNDSVWARAEKLFQDKVALLPAELQKREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR17</accession>
    <name>A0AAD8XR17_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_564090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371995.1">
        <property type="nucleotide sequence ID" value="XM_060503608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR17"/>
    <dbReference type="GeneID" id="85387507"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1033" mass="113109" checksum="E5633CC6CC83C779" modified="2024-05-29" version="1">MTATGAQRESTKPQRGRSDSLQKMLELEHIRKLERLQGHQSMPAATHPSHLAFQQVLQQQLNHGRPAQSPPKLKPFPTVHPAPPVKPIAPLQSRRRESSAQLPTQKPELPPSAMKAVRRATALPSLSISVPPPSNVKSEIDRGSERKESVEHKHKTVTFLDVDMVDEPTADDASSICHSPSWESFGQNKKKEKKIEAKMRKKEKEQAEKQAEKEAKSVKKKLAAKLSKAGPNTKASPPRPPNASRSISSPTVFVNEHLRSASAQAFYEPPPSIRPQHARQRSDSVAMQLKAALTGHKTHNQSHSNDDQGFIGGLKLEQKRQNDAGMPFRKPNPPAFLTGQRSHSFGPEVRVTPPAMTPSALPRSFSFDPQGERPDEYDEDSYRPKTPRSASTNTPSWSQPLVSPTAPPVPDVSNFQQWMNRTKQSQAPVDDQELEIHNGLSEFVVEQERGRRRESYVHQSRQQSRERSINGYREEVRVLSAKSHYPPASNRPLQSRAYSSSSESSPMGSNFPPRNGSLSSLGGYKDQPTPGEDFTLTFRLPYTPPAGSPGQQSFDRSTSQGPPMSKMMSKEIPLPPERSASRERHPATPGAAIRSFKDAAKAAFQKVSTPGSSKPPVSNYFTRTARDTTMTPDSTSSSRYSTDEPSPFTAPPRPFAESTESTSRDSSARPTHRSSMSSCDESLPSPSPATTPDSSRPQSEKGLPPLDGELGRVDIETVVVTNDTRSYRLSHKAAMQTASPIATNQRISLPPQIPVQNHEAHLNELEALVTEKFGRKASVADAEDSDSSQNYPTPTHTDSSKTSAMATPLTSASLTIPFDYGKNGHAQEVGNNIEPVQEEVHSVVQRHPSLTKSRSSPDLALDTSFLPKLKHQPLVPRSLVPPPPPRSSKRGSVTNLHAKAASQSSFPADVASRKSIVSTKGPSNPSSYLEEARKSMPPPRSSRVSRASIVPANGIPEPVAKMLVECCSCKFLHDMPSKVYECMAKPDSMVEDRKLGVSGLISTTVKCPWCAHGMTTNCCAGYAAVIYLKEKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZG9</accession>
    <name>A0AAD9CZG9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_647982</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">In complex with CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The MON1-CCZ1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endosome</location>
            <location evidence="4">Multivesicular body membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 4">Prevacuolar compartment membrane</location>
            <topology evidence="1 4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Vacuole membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369393.1">
        <property type="nucleotide sequence ID" value="XM_060510136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZG9"/>
    <dbReference type="GeneID" id="85394035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="6">
        <location>
            <begin position="179"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="7">
        <location>
            <begin position="341"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="8">
        <location>
            <begin position="487"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="597" mass="65534" checksum="65040C694070CF8A" modified="2024-05-29" version="1">MGEDHENGPSEEQPPPLPPRPSMESNDSIDSRMAMAAATTAVTPLDIQTLSFPDGSRGTFSTTGSRAVSTPVQSSSGQATPTRTLGEGEDSMSIASFSPTLRPPNDIASLLMGEFNKRSPAWNLLRSQSATVPPFETLRMDNTTRNLAGFEHEFDDLPDEADTSFKDEDRVTMWKAKLKHYMILSSAGKPIYSRHGDLRLINSSMGVIQTLISFYEGAKNPLSGFTAGTTRFVVATQGPLYFVAISRLGESDSQLRAQLEALYMQILSTLTLPTLKNIFVHRPSSDLRKPLEGTEPLISSLADNFTKGSPSALLGALECLKLRKSQRHAINNAFLKQRTDKLLYGLIVAGGKLVSVIRPRRHSLHPSDLQLIFNMLFESGGIKAGGGENWIPLCLPAFNNRGYLYMYVSFFDGVDGEQATGHEAPVHKDEELAIILISPDKESFFELKQMRDNVAASLAKSGHLSLIQTAARAGRPKTTDIAPGGQISHFLYKSRANVQFSMSALDPVFSSLMARRRLMGLYHQLHAAVHAKHSHMRVLHSVSEDATSLAWITPIFEFYCVAGPNVSRAVLTQGANKVIQWARREEERVFIIGGGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0G2</accession>
    <name>A0AAD9D0G2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S24/S26A/S26B/S26C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_607134</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369261.1">
        <property type="nucleotide sequence ID" value="XM_060507410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0G2"/>
    <dbReference type="GeneID" id="85391309"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037730">
        <property type="entry name" value="IMP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46041:SF2">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peptidase S26" evidence="7">
        <location>
            <begin position="31"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="179" mass="20655" checksum="32A73ABC5D200C49" modified="2024-05-29" version="1">MASRSLWARARGSFLGDTTLRLLGLATWIPVVITFNDHVATITSISGGSMYPYYNEDRNMTTANDMVLNWRWKPSYGLQRGMIVTFRSPFHPETVAIKRVVALEGEYVTTRAPYPERVVRVPQGHIWVEGDGPQDQTLDSNTYGPISMALVTGKCIWNIWPWRKFGRVKWEEHKFKDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2D5</accession>
    <name>A0AAD9D2D5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_245074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371357.1">
        <property type="nucleotide sequence ID" value="XM_060501894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2D5"/>
    <dbReference type="GeneID" id="85385793"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="40991" checksum="C95833833DBE00E8" modified="2024-05-29" version="1">MRRPRDGTRFIIRCLEHREIECVDCPQPRDAHAAEYLRSLRPIPRPPREGPSDTDLARARRPVYFFYSGRRPDLGDPYVSNNNDDALSDIEGELDYPMSDDDSSDWSLSSCPGLPDGSSADHERSPKMQISPILDCPSIQYPEFEYPERPYQSANGRLATRFINTHDHTDFLMYIQGLCRPETRTGSWAYLFKPYHLGGAVAGRLERLGPYGDLRTPVRHRAELRAALAALTIPADFRHGFRSLTIATTRAWLAEDGELLVEQAWDEINEAGSNPLPEWAEARHTPEFAHVSDGDLWFAMKRQIQNLYSIDDPQNAVTVQFRLIDFEFNRDCQGEALGALDNPRRPYRFREPKPKQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6Z7</accession>
    <name>A0AAD8U6Z7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_798214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000289">
        <property type="protein sequence ID" value="KAK1703159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357239.1">
        <property type="nucleotide sequence ID" value="XM_060515922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6Z7"/>
    <dbReference type="GeneID" id="85399820"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="20782" checksum="9AE55FA8DCF65169" modified="2024-05-29" version="1">MFNEYSQFVLRNTAQMPITRFTMPRVPKMIEAICPGCFKGFTKIGSMHRHVYEDRCPHPIPQFVAKVKAEHRARVAATAARSKARKAARASRVDPLPAAPTPAVRDHPSRARENSMGRSPGFLQNDCSSHFAQQRDLEMLSQQQQNDFCPVIKTEPDFSAFNFPSLIASWDTYDVGINIKTESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U734</accession>
    <name>A0AAD8U734_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000283">
        <property type="protein sequence ID" value="KAK1703428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357284.1">
        <property type="nucleotide sequence ID" value="XM_060506782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U734"/>
    <dbReference type="GeneID" id="85390681"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="1">
        <location>
            <begin position="10"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="11706" checksum="FFDF04FAD894D5A3" modified="2024-05-29" version="1">MAALEVAAGDFSATCSGTSYFSTTVKSSCQDNYQEDSYSTDLDMTKCLANVGGRVVCRPSNPSFKFCDCGLGGDKKQILNCRCTDSTGTKRPSSLNLDTCLSNINGDLKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7K0</accession>
    <name>A0AAD8U7K0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl hydrolase family 36 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000257">
        <property type="protein sequence ID" value="KAK1704795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357494.1">
        <property type="nucleotide sequence ID" value="XM_060515075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7K0"/>
    <dbReference type="GeneID" id="85398973"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.60">
        <property type="entry name" value="alpha-galactosidase from lactobacil brevis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038417">
        <property type="entry name" value="Alpga-gal_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031704">
        <property type="entry name" value="Glyco_hydro_36_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16875">
        <property type="entry name" value="Glyco_hydro_36N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 36 N-terminal" evidence="1">
        <location>
            <begin position="55"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="57299" checksum="36E492B0E913BD4A" modified="2024-05-29" version="1">MGEKQIQTIRWHTDALKIDFLINKDGVICVDRILPTTVEPSPRSSPNFESSELPLVSIRVSAEGSGDIKTAKTLVDTTLSDRLRYQSHRIIKSDDGSKETLTVDCSDNATNIHVVASFTIYGSIPVVRAQTTITNQSTNNQDIVLSNISTLMIGNMTSTSDRWFEDYSLFHANSTWFREGQWEERSLPSVGLDNNGVLELGDGLLASLAHFELSSRGSFSTGGHLPMGALKQRNNEDTWMWQVENNASWRWDLGDFKDSIYLAAFGPMLSSHGWKKRLSPGQSFTTVPVACCRVKGDEQATFAALTDYRRQIRRPHDDMERMPIIFNDYMNCLMGDTDENKAYPQPGWTDELNALSVVNSIMGRVYLSGRIDLLSDNQLAIVKEGLEVYKSMRGDLHYAHPTWPLGLPKWHDDWVALALTSADGKTTYLAVWRRDGPTEVNISLEDKLRTHKDSKVSVLYPNRFTTKAELDGAEYVLHLKLPAEPCARILKIESQNTMSYLITGYHPAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8T2</accession>
    <name>A0AAD8U8T2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Long-chain specific acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_759033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000311">
        <property type="protein sequence ID" value="KAK1702422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357127.1">
        <property type="nucleotide sequence ID" value="XM_060515126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8T2"/>
    <dbReference type="GeneID" id="85399024"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF15">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE APDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="22"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="155"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="263"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1702422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="437" mass="48149" checksum="3A99C6DD3ED8059D" modified="2024-05-29" version="1">MSQVPFADPPWLRGLPSPYFNDSHRRFQVACRKFLDENLHKDAMDWETAEDVPSDLFAKFAKGNFLIPALPAPLPVEWLHKLGVTHMPGEVPVEEWDALHTMIYSDEMSRSGLAGPPGSLTTGMAFGVPPLLHYANADVQNRFLPDLLLGRKRTCIAITEPDAGSDVANITTTAELKGNEYTINGAKKWITNGVMADFATIAVRTGGEDSGGKGISLLVVPLANQPGVSRRRLKVAGQIVAGTSYLEFDDVRVPRENLIGKENEGMKYIMHNFNHERMFISVGVTRQARVALSAAFAYCMQRRAFDKTLIEQPVVRHRLAKCGAILESQYAWVESFAFQLSKMPKKTADEELGGLTALCKANAGIVLDECARCAVLLFGGNGYTRTGKGEIAEKIYREVPGARIPGGSEDVLLDLAIRQLTKRFRAETVKDKTRSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9D5</accession>
    <name>A0AAD8U9D5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_772565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000276">
        <property type="protein sequence ID" value="KAK1703672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357335.1">
        <property type="nucleotide sequence ID" value="XM_060515388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9D5"/>
    <dbReference type="GeneID" id="85399286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF15">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="104"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1703672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="48035" checksum="F092CBD2097AC0ED" modified="2024-05-29" version="1">MRDHGHHLRFGGKVCCLYIFSEILFTTSSVFAECSYRSRFLFETRPRTVSSIPTQLLRNRRRGSVMSNVAGDDTWQAVEPQGLALGLLVTTVTLAILTTIVMAMRMFIRFKTNKIGSDDWAMLTGFASRRCSGQSAVAIYGSFTGIASKDEIMNRATSIEGYKTLLIWQAFYAGSLCFIKSSICITLMRITNQKVYLWILRGLIGLSFLMSGSGLIVILNQCHPLDRYWDKSIPGTCWPPIVATALSYGASVANVITDFSVAAIPFFLLRHVQMRSRLKFYVRLILGLGLLAGIASIIRVPFTNAYMKASDVLYHAGNIVLWTIVECGLGIIAGSLPMLRAFFKRLAKDTSTQEPYNRSGDTNLVTFGQGKGRQGPIYETDLGVTVIGGAGDNDSNNSNHDDDAESTRRIIKVTREVRHSVTEENGTMPAKRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9R6</accession>
    <name>A0AAD8U9R6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_656961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000165">
        <property type="protein sequence ID" value="KAK1710907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358967.1">
        <property type="nucleotide sequence ID" value="XM_060510923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9R6"/>
    <dbReference type="GeneID" id="85394822"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="19654" checksum="579221F4968BE6F7" modified="2024-05-29" version="1">MASNASFSDLDAPRGEMGSENNNINNDDNNQPGRSTGTSSAGASLGNTAATAHQGISQGDHAGVMDEQKVKEMQRLHAAIEEERKAHIKEKQRLEAEFQAEKQEKERLEEAVQEQKNREQKARIQRAIQATPEELAAYHQAIEATEDMRRSERRRANTLGRMNGYLEAWGKKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9W8</accession>
    <name>A0AAD8U9W8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_655862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360207.1">
        <property type="nucleotide sequence ID" value="XM_060510824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9W8"/>
    <dbReference type="GeneID" id="85394723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="648" mass="71399" checksum="8566E7AF49752003" modified="2024-05-29" version="1">MCQVTSLHRYSQPFLSSKHSGPVVPTAPWVLSTRRDLSALPSFPFLPYTYGVHTPTYHLTYDLITPRCAPLDLLDLIPALTTRTTTTTTRRQTRLSLPTFSLLPQSMAHTAVANTRSRPVTITVVAHHDDKYAADNMTRSASAEPTKPTKRKGTRSVSTLTPSQLARKRANDREAQRAIRARTKEHIERLERELEELKSERGRDQSQTVQELLRKNKALEEELFKLRESMGVPNGQSYPNSGTAASIASSSAWLPLVRADSAPVYDDNLSSISGAVPSPRSSPFPSNGDYNVMQELGPSYVPMPDASESWGPGIPVSVPSTVSSPSSSANTDEYGAGYIPTSVPAPMMDARSIPGKMSEYDDVDSVAGSHLSSSSVVSSSPAVVEFVSNSGVLPTTVSSLIRQPGTTLWEIPTLIVPPTCRIDQLIVGFIQDCRRLSQLKSLDNLLRPARVNVKNFLEYHPTSPTTEPPRCQLADLDRAASTTVTGPGAKHPMAELITALVNKAGVTNVIERLAVFAVIQRAIAWLVHPTREAYQAIVPELTPKPCQTRIPHPQWVDLILWAPLRTAIIERQELYANEEFQGVYSASLRLINWPCRPIDALVVDPQSGEMWLSDTFTAHAMRLENWRLNENFVRRYPELRGCVAVEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAD9</accession>
    <name>A0AAD8UAD9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_593698</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357859.1">
        <property type="nucleotide sequence ID" value="XM_060506653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAD9"/>
    <dbReference type="GeneID" id="85390552"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042129243" description="CFEM domain-containing protein" evidence="16">
        <location>
            <begin position="17"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1706604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="183" mass="17558" checksum="2161A341EDEAF767" modified="2024-05-29" version="1">MKYSYVLLATASLAAAQQKFTDVVPKCSIECLTKAVKDGTKCSSIDDSACICEADNYRSIYTVGVNCVLQACGSDVAIGQLLPAAGKFCREVTGGASAPPVDSASASASAVVSSAIASLSSAAASASTAASNATASVSITATPTAGASSTAAAATTASQAGAAPALASMGALGMLALGGLAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBE9</accession>
    <name>A0AAD8UBE9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358491.1">
        <property type="nucleotide sequence ID" value="XM_060509566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBE9"/>
    <dbReference type="GeneID" id="85393465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="253" mass="28949" checksum="0B4EB6122C2D813A" modified="2024-05-29" version="1">MSTINYYERITEVYRLDNTPILIASAVSFIIGYLQYTYVVRLTLREGKGPMPFWMHSFYLAHDSTWSYTLGKAASQYGEHWYLRGNSIALFLWTMLEVWTIHRSITKERDASFGNILGKQPSMYAAITYALALQMGMYSVVLLAIEFMGEGSVMQWFCFTNVLIVLGPTHHYLRAGSRHGLSLGFCVVNIIGTIWTFAPFGFFVLTIPEIFDQQLYYIIGVILTVYSVGCFHVVSQYPSKTRVMDKGGKQPIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCP9</accession>
    <name>A0AAD8UCP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_590131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359400.1">
        <property type="nucleotide sequence ID" value="XM_060506308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCP9"/>
    <dbReference type="GeneID" id="85390207"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="39305" checksum="54FF71C9721BB8E2" modified="2024-05-29" version="1">MDASVTTPLLHGQSEFHDGHGLPTPASYGQVQDHPAFLRACHSPWRSFSQNHLCWVRGGIVAYLTGVGATVLDYKLRKEESPYSDWRVVFDFSVVTYSLLLAYHAVVLGWTYTHLYHPHIEEISTGWEYWALRTLSLPYDMASLRKQFYFTLFYTITTVFTFMNTVIYWFVTLEHDDNNTGEPPKPQPSGGSAMANMIGDSFASEWSSLADSHKNGPHEPFTEIFGKGWYKAFVIINLFGITSVVSLIEIFWLNSIKRPFGVGAHTLGVIFFAGLYLGWAAIGKVETGADAFYWLNEKNVGSREAVVASSIGFVILAPIMYAFMYGLVGMRENMARAAHTRRVAAAAAVAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCS0</accession>
    <name>A0AAD8UCS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_590171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359384.1">
        <property type="nucleotide sequence ID" value="XM_060506312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCS0"/>
    <dbReference type="GeneID" id="85390211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="35733" checksum="FDB28411D74606D6" modified="2024-05-29" version="1">MSSTTATKSIVGKSIGPTGYGLMGLTRPWDQIDFSVSTKLMKTALEQGANVWNGGIHYGTPDRNSLHLLKHYFEQNPQDADKVVLSIKGAYDGKTHIPDCSPEGIRASVEEAVRVLGGSKKIDVFECARVDPNVPIETSVQALAELIKEGKIGGIGLSEVSAATIRRAHAVHAIAAVEIELSIFTPDAVTNGVAEACHELGIALVAYSPVSRGLLTGEFRRPEDLPANDMRRMLPRFKSDAFVQNFKLVEAVEKIAERKGATVAQVAITWVRRQGAIPIPGSTKAERVVQNCVDVELSDDDLKEIWALIESLPITGQRYGGKFEQYLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDQ3</accession>
    <name>A0AAD8UDQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_589834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359509.1">
        <property type="nucleotide sequence ID" value="XM_060506272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDQ3"/>
    <dbReference type="GeneID" id="85390171"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="122"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="553" mass="63107" checksum="56F568F782263D81" modified="2024-05-29" version="1">MRFTNPFSHPPRDTYERHSLIAEQDGRASPSTESLDEIIDIEKREYPFLVSVRSARNSVSSFLNEHLHLGGDLTWTDRLLTLLTTLKPFVFLFLPTFFISPFNYFTTPLGQRPKPRKLGPTAYLDGLRGVAAFVVYIFHFSYLWFPDLRWGYGFAGHQMFWQMPIVRALHSGRASVTVFFVISGFVLTLKTVSMIHKRKMDQALSALAGSAFRRPFRLYLPIFASTFIIALLVYGGEYVRDPSGAPVPPRGPSLDQQLQHWFWSTVNLMNPFRAIVNRENMKGSEYDGHLWTIPVEFKGSLLVFFLLLIFARAKRWVHMVGVTGITLWLVHIGDWDQALFCAGLLLAELSIIMPNTAPTTETTEDQLPSYRLRTVKRYGSQSIHIFRHAGTVALFFLGLYLFSYPEYYGASTPGFITISQWVPDYYKAMGDRTQLYWNSIGAIIFIFALMYSPPAEPLLQRPFTTSFAQYLGQISYSLYLWHGAINHMVGVRWLSPAHAALSLAGAQAKLAFFWGSLVNTLALLWASDVFNRIVDVNAVKLTRWLGEKAWRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDR8</accession>
    <name>A0AAD8UDR8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_125341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358865.1">
        <property type="nucleotide sequence ID" value="XM_060501177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDR8"/>
    <dbReference type="GeneID" id="85385076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="21826" checksum="F0FF712D00393704" modified="2024-05-29" version="1">MQLSTGAATCQHLVIGVVSAAIAFVGRCSENGLGFAVGHYYARVSFRWCSAAYVDPGLKSCTYIECVLWRIETRLRSPGESGDDTRQSKATGPAPSQFLVMQTSLDSIGQVFAFVQAAGLLHQPDQLFVFRRSLWWFDCPFVERFVSGTLNQVTGGLLYAHLRHNALDWLVCQTMATARRHRRFLLCAGLNFPCQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEA6</accession>
    <name>A0AAD8UEA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_721308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362652.1">
        <property type="nucleotide sequence ID" value="XM_060512377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEA6"/>
    <dbReference type="GeneID" id="85396275"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF1">
        <property type="entry name" value="CIRCUMSPOROZOITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="50758" checksum="00D6300319F56D1A" modified="2024-05-29" version="1">MKYQTIAFATSTLVGLVAASPYHRHHHLRRVSKREVPQEHSHEIFLNITREFLNKENPKAIADPVFGLLGDAAAKTGAGQVTNLACLQQETADQAFTNAKAAKDIRGMSAALVYQTLERNTAGVGVNSAACTDKPVNAEIAALSKKHQDPAADGAAANNKEVALALAKQLAAVGGDPMLALESGTFAPGDKSDTTFKGLSCDTDTDPTGCIFTEKKLVLDATPDEITAAAKGVTQTVTGGTGELKATHIDITGLAVAGQTGAQTQANNGTAGGNNGNNSNNNGNANSGNANTGSGNNVQTFTGSLGGAPPPVIQSSGDRPFSVNGDTFVGKGAALGRSCDVQHNACARAVNSGQLDGEVSQCDEQNTQCRAQANLRKRFFKRQATDFGSCSDPSVVFKDGLPDRQAAAFIANNQGDFNHGSAQKIGIIAGFICQRLSDSCKAPAATIESCNKAQTAAVAATQDETAANVFNSMLIGGSASGNVTARGELRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEB9</accession>
    <name>A0AAD8UEB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T-complex protein 1 subunit zeta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CCT-zeta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_588310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360179.1">
        <property type="nucleotide sequence ID" value="XM_060506125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEB9"/>
    <dbReference type="GeneID" id="85390024"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1715036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="58979" checksum="9C080E104BE85805" modified="2024-05-29" version="1">MSAAQLLNPKAESRRRGEALKVNISAGEGLQDVLKSNLGPLGTIKMLVDGSGQIKLTKDGNVLLREMQIQNPTAVMIARAATAQDDICGDGTTSAVLLIGELLKQADRYISEGLHPRIITDGFEIAKNEALKFLDGFKLEKEVDRELLLSVARTSLSTKLNSNLAAKLTPDIVDAVLAIYQAPAKPDLHMVEIMKMQHRTASDTQLIKGLALDHGARHPDMPKRLENAYILTMNVSLEYEKSEINSGFFYSSAEQRDKLVESERRFVDAKLKKIVELKKEVCGNDPTKNFVIINQKGIDPLSLDVLAKNGILALRRAKRRNMERLQLICGGVAQNSVDDLSPESLGWAGLVYEQTLGEEKYTFIEEVKEPKSVTLLIKGPNAHTITQVTDAVRDGLRSVYNMIVDKSVVPGAGAFQVACAAHLKSDAFSKTVKGKAKWGVEAFADALLIIPKTLAANAGLDIQDALAAMQDEHADGNIVGLDLATGEPMDAELEGIFDSFRVLRNCIASSSSIASNLLLCDELLKARQMGRAGGPGPGMDGPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UED8</accession>
    <name>A0AAD8UED8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Transketolase</fullName>
            <ecNumber evidence="4 15">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_722188</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4 15"/>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361438.1">
        <property type="nucleotide sequence ID" value="XM_060512448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UED8"/>
    <dbReference type="GeneID" id="85396346"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="16">
        <location>
            <begin position="356"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1719354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="685" mass="74971" checksum="7A9503B3C6861971" modified="2024-05-29" version="1">MGYTEQDWKAINTIRLLAVDATFNSNSGHPGAPMGMAPVAHVLFNKFMKFNPKNPNWLNRDRFVLSNGHGCMLQYALLHLFGYGVSIDDLKKFRTVDSITPGHPEAHDTPGIEVTTGPLGQGISNAVGLAIAQAHTAAVYNKDGFSLSDNYTYTFLGDGCLMEGVSGEASSLAGHLQLGNLIAIYDDNHISIDGDTNVAFTEDVVKRYESFGWEVLIVDDGDNDLDSIEKAIAKAQQSKDKPTLIKLRTTIGFGSLQQGTHGVHGSPLKADDIKQLKEKFGFSPEQSFAVPQEVYDLYNKHAAEGAAAEEEWNKLFAKYGEKYPNEAKDLSRRLKGDLPEGWEKSLPVYTPADPAIASRKLSETVLQKIHQIVPELVGGSADLTGSNLTRWKEAVDFQAPATGLGDYAGRYIRYGVREHGMGAIMNGLAAYGTIIPYGGTFLNFVSYAAGSVRLSALSQIRAIWVATHDSIGLGEDGPTHQPIETLAHFRALPNNMVWRPADGNETSAAYYVSLTSKHTPSIIALSRQNLPQLEGSVIEKGIKGGYVLHEDPNADITLVSTGSEVCICVDAVKYLKEKHNIAARVVSMPCTEVFDSQSKEYKLSVLPDGKPIMSVEVMSTLGWERYSHEQFGINRFGASGPYKDVYKKFEFTPEGIAKRAVATVEFWKDVPNVRSPLNRAFQQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEI9</accession>
    <name>A0AAD8UEI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C4-dicarboxylate transporter/malic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_723184</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360081.1">
        <property type="nucleotide sequence ID" value="XM_060512531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEI9"/>
    <dbReference type="GeneID" id="85396429"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09317">
        <property type="entry name" value="TDT_Mae1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030185">
        <property type="entry name" value="Mae1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162:SF0">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31162">
        <property type="entry name" value="MALIC ACID TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="47160" checksum="7BCF4F472EC08AC6" modified="2024-05-29" version="1">MAAADEPSNVVSKASTRTRDEGQISDEPPQNALMATLSRTKSRTNTLLEKVSLRERIHHFTFAWYTLTMSTGGIALLLAETPHRFPGLDTIGLVVFLLDIVLIFLITLALCLRFTFFRKTPAKAITHPSESLFIPTFFLSIAAALSNIQHYAVPKCGPWLIVTLRVCFWIYLVVTFFASVGMYHLLFTGRRRLSLDSMTPAWILPIFPVMLSGTLAGFMASSQPPNQAAAMLGAGLAAQGLGFLVSAFMYATYLSRLMTIGLPVQRPGMFIAVGPPSFTAAALVAMGANVPRLIASEGSIISDSLREAAYLYGMENPGTVAFAVRAVALFTAVFLWGLSFWFFSSACLSTMFGMPDHSFHLSWWSFVFPNVGFTIATIRIGEAFGNEGLLWLATVFTLALVAVWLFVGFCCARAVIRRKLVWPGRDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEN5</accession>
    <name>A0AAD8UEN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_628887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362581.1">
        <property type="nucleotide sequence ID" value="XM_060508730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEN5"/>
    <dbReference type="GeneID" id="85392629"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="13270" checksum="A175775CF574A41F" modified="2024-05-29" version="1">MLPHSRHYLPGRGRDVSLQMWFWISFTCIGAALAPICEPQISPTLVPFYGVREENKAHQKPSQFLLAPVPRSNHAALGRLIPCFAGFFIVLSLRQALAFQWQSNTLNLPHPQGWPGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEX1</accession>
    <name>A0AAD8UEX1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_457152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361712.1">
        <property type="nucleotide sequence ID" value="XM_060503202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEX1"/>
    <dbReference type="GeneID" id="85387101"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="555" mass="62809" checksum="E2AA95AAA383B554" modified="2024-05-29" version="1">MGALEKSESTTRIIAAMLCPRQDRGKVFRHFAVKQLHLETHEEYAREVELFERLGMGSRGPDPDHLIQLQLTYKYGQSYYLVFPWADGNLKEFWSQNIANPESKAESVWFLSQCSGLVRALRRIHNLRTMSKEDNCVPVPNEPNSLLDNKHWGRHGDIKPENILWFKKYEESRRNFLVISDFGLTRFNSVDSRSKVAHEALRGFSGSYRPPDVDLKRTISQRYDIWSLGCVFLEFVSWFLVGDDRTQNDFTDARIQEDGLHTGSRILVEDKFFNFNPSKDDTPSTAEVKTSVTDWIDYLHRQESCAEPVHEMLNLIQHTMLVPDAKERWACSRIQPVINDLIRKSKCDTAYATIGTHGVSDPLRFPCISVESPAVCDQPDNICHVLNDIGEQEGKIPSLPGTPEKAVRRDRSLSLSPAAAISSRGRKPSQTNDRVKRPPVKPVVSPIQSSYFSRSVTEPSSILASEGESIARLVRLLSFSTEDSTQLIMSLSEAASSFASTPDMSPFPSQSGEDCFDVLEQNLVLRQKEACEGVKVPNEKQPTQRREEAIALTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF53</accession>
    <name>A0AAD8UF53_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_630833</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361873.1">
        <property type="nucleotide sequence ID" value="XM_060508858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF53"/>
    <dbReference type="GeneID" id="85392757"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="50594" checksum="2A80918CBFA2485F" modified="2024-05-29" version="1">MHLRESNFTKKAMVGIAKLPPEVIQHIFDQLSTAPSYSHLYWVDASFKSKLSDLEALSRTCRAFRQLVGRNLFSYVWLVKPGHNHLISLIRGWDSRPDYTQHVRRACIPIHAPEQSPRQQEMRLSGDEVPFIEEKLSKMGLAVYPKGWNGGGHVNILAIMVPLMAKSLRELEIQYILSEDHRGHGVSNKLLLMENDVFPNLETLHIKCTPRVGQFPMELVKAISKNAPKLRSLKIQCFDGAWFDGSQTWEKLTNIYIWSSLNVQPFIMEIISTPKHLSHFGLDRCVSSVSQMVNMIDALAEHKGTLKALSVRFPDRSTGETASLLLHKLCNLEIFTTQLQDAGTQDENILRQLPKSLRKLRIVRARGHHHNHFAHHYWLEEHLRRLKKTGKHCSLQVFVCDTWEEREGEEKLDFDGRDEDSIEKGYLAEAVDWLYLIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF58</accession>
    <name>A0AAD8UF58_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cofilin/tropomyosin-type actin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_587676</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360438.1">
        <property type="nucleotide sequence ID" value="XM_060506066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF58"/>
    <dbReference type="GeneID" id="85389965"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="16008" checksum="B3710EC40B431B67" modified="2024-05-29" version="1">MSGLDAPEIAAAYDAVRSDKDETSWLLISYASAVGNKMTLTKTGTGGLSELASELDDSQVQYAYVRVEYANDVESKRVKFAFVIWIGQNTKIMRKARVSIESSEVKRVLPHHSITVNADHKGDLDEDDIVKRLRKAGGADYNGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFI8</accession>
    <name>A0AAD8UFI8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquinol-cytochrome-c reductase cytochrome c1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_438364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362143.1">
        <property type="nucleotide sequence ID" value="XM_060503091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFI8"/>
    <dbReference type="GeneID" id="85386990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="46733" checksum="FC21421BD2EB1516" modified="2024-05-29" version="1">MASTMEEEIYLAMQDVFSKEYAEIRHQKAIKRRIHACLGPEIKALDLKYTRPVVVSTCQELLGKEVFGIRWKAEQRFPQLFQHPPSPQAVATSENAPESPEPRRQEMDWKEKIVALIAERKAERFSRLQATTASDTTSDAAGSIATTSSDTAIAESTATVTERQPPIETATFSGLRNAFLSYEAQHALFIRIQNLLETACFDYARQAHPKILEAGQWESPECVELQKWMWIFENEAFHTFRAETAPLPHTDWHAFFKSIKQIRHKAVHREVLCVADVKAYFANAESLAKLLRQDECLAKLGTLREETEMVLAISERKKDGLAVKYQFKFDEIEARRKELDELERRTREEMVQEHRRMQSDLGYGFKLAVAEIKEAEILRKRGQAGGDKEEGAGSWRLVDGFWNLVSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFJ5</accession>
    <name>A0AAD8UFJ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_587762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360409.1">
        <property type="nucleotide sequence ID" value="XM_060506073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFJ5"/>
    <dbReference type="GeneID" id="85389972"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="34"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="11916" checksum="2E49079207E29C49" modified="2024-05-29" version="1">MAIKVNSKDKDEGEEPGEQGNSSRLGPKKGYGVKNRAAANRSREKAKQYEQHLAAKEYEVTKERIYLGARLTALKGEVLNLRNQILQHGDCDCEVIQRYIARTAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFK4</accession>
    <name>A0AAD8UFK4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_756681</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359825.1">
        <property type="nucleotide sequence ID" value="XM_060514783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFK4"/>
    <dbReference type="GeneID" id="85398681"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1760:FF:000001">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="14">
        <location>
            <begin position="229"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="162"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="238"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="303"/>
            <end position="306"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="449"/>
            <end position="452"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="513"/>
            <end position="514"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1713772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="526" mass="57892" checksum="E0E95E9FCF919252" modified="2024-05-29" version="1">MANPTLTREQYPPRLSQSEQDALVQTVKDWAIGNGLSVRPPPTVVTPESDPKGILAVNVPVTLFPSPFPKGCFEQARSVQKTYNELYAAISRDEEFLSAMVDEVKGGDDFIGKLWDTHVRVKKEGYTQSLSLGLFRSDYLVHQDTSSGQPKRQVKQVEFNTIASSFGGLSSRTSLLHKFLSVAEYPLLDQPIESGSLDLPENKSVQGLSGGIRAAYDAYGPSELGHKKCVIFVVQGGERNIFDQRHLEYALVNDAADPVTVFRVPFSELLQHTTIADTPKRQLLYKLPRDPNKVFEVAVAYLRCWYDPSDYPDESAWEARYHLERSSAVKCPTVLTQLAGSKKIQQVLATPRPAATAAAGGASPSILGRFIPDDAPSTAAVFETFTNIFPMDTSEAGLKARKIAQDPELCKSYVLKPQREGGGNNHYREDIPEFLKKTPETHWGSYILMELITPPKQDNIILRNGNLEEGGVICELGIYGTTVWDQDTGKVVHNEEAGYLLRTKGDTSNEGGVAAGFGCMDSCTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGZ5</accession>
    <name>A0AAD8UGZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_675645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362732.1">
        <property type="nucleotide sequence ID" value="XM_060511154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGZ5"/>
    <dbReference type="GeneID" id="85395053"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:protein-N-terminal-alanine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000047">
        <property type="entry name" value="Acetyltransferase, GNAT family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF2">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="26714" checksum="E206BA6E01694315" modified="2024-05-29" version="1">MDFPVDPLVASADPATAPSHTPLHGRYTSVVPLQPSHAQAIFKHLGREENAWRWTYLLTEPFLEFEECEAAFKEWSVCKDPLYFTVLSGPASDPSSEPVGVMAYLSIVPAHRRIEIGSIIFSEQLKQTRTATEAQYLLMKHAFEGLGNYRLEWKANHLNKPSLAAAARLGYTYEGTFRKHIVTKGRRRDTAWFSITDDEWPLVKSGLEMWLSEENFDENGKQRKGLKQCREAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHF7</accession>
    <name>A0AAD8UHF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_623409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364407.1">
        <property type="nucleotide sequence ID" value="XM_060508381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHF7"/>
    <dbReference type="GeneID" id="85392280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="113" mass="12228" checksum="E4F6D5DD38DA5819" modified="2024-05-29" version="1">MPRLEAPFGFPRTDGRSWTPAAWVHWVRKAEACSPHVLHALGHPLPTPKSSFQLLRPTRSHSSLTHTASCVAATLAVPNYSLVRLCSNPTVAGAVRYVACGMWHANSDTGADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ95</accession>
    <name>A0AAD8UJ95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_412212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362819.1">
        <property type="nucleotide sequence ID" value="XM_060502919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ95"/>
    <dbReference type="GeneID" id="85386818"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="334"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="367"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="400"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="688" mass="76541" checksum="0897F8583E002F3C" modified="2024-05-29" version="1">MQMVPNVQRLESSTGTGDAPESPTYKDERSPLLGEDSAALQDDKTLQAVAVRQTQQALSNPQASATAGVSTHQATNVVSSIFNQTSGLLQDRCPIPCCCRCHASKPVSYTPTRWARSLVGSLNLSFNRQLTFQNNTKCTEDSCKNRAGTSIIVEYQFPLWLCSRAVQMQTLVGVTTGLRVSLRPARVLPFSSSFWRLIDSDCSESSKVTVQQWMLHHGNVFPGDASPNGVTALEWVIGQGTTDVFLYLFQIWEDQILNGNYDDSWFYEAHDKIANTASLPEQKMQVLTRILSAGKWTVNASQTPLHDALCRGDFDAAFRAAKDFSWALNQRNYEGNTPLHIAATQGHLNSVKNLVQLGCDINEANWTGRTALMLASKGGHILTVQYLIDAGSWVNATDRGGDTAMMVAATAGHNNLAAIIQSLIRAGASVNITDQQGFHAIHHLTSSYNKGRVIRESLRVLMEAGADIESRNRPGRTPLLVSIQSGDRRGTQCLIEAGAKTTYVTRDGWGLLHEAALYGTTKTLRYLSTLNLQTINTGLRTGDGETPWDYLVFSIHAQDWQRAGTLTLTSKRQEAFVSLFRSIRDRNLTLDIERLDWLLQYLKDRDRRGAIAALSPLIKQKEDWKRWEILGTYKAIGLQVREEMWEAAVESVEEVIDCLRERMATSPCDSESYYDPITHTIYRARELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJV4</accession>
    <name>A0AAD8UJV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_287590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365742.1">
        <property type="nucleotide sequence ID" value="XM_060502170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJV4"/>
    <dbReference type="GeneID" id="85386069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="33295" checksum="81ECBE511E2A4E5C" modified="2024-05-29" version="1">MEIIQCKCASCQARLATFFNLWTQVGKSYFSPTIEAQGITQMIAKEPTRIGEAGYLVAGCELQDVACATCGNIIGLKCLSSPVNHVLHDSQILLRQASIVSLKKNGTPVELYVRRKLKLRDDSRPGSYSANNHLNSDSRQGFGSGHGSPNSEHIDFSRLRVDVDAQRESIERIDAAGFQVVSQLNSAVSRIEKEMAKLNSTMDQLQSDLDLHKADLKSVKTEVFSREYSTQNSPELSRLESQVRTANTAISEIKKLFEEVKRENYELRNDLQTSRKDHKWLKSFTLGLQSHPVYKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKJ7</accession>
    <name>A0AAD8UKJ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_276374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366072.1">
        <property type="nucleotide sequence ID" value="XM_060502098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKJ7"/>
    <dbReference type="GeneID" id="85385997"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="35708" checksum="E02C94D334C2814D" modified="2024-05-29" version="1">MSLDINSLLNPEKAVNRETEALMMFTGIFDEFRKTFPRHRQREGELAYMADVTMHVFDAFKKFTDDYLTKERLESTGHNLVDQAYRANGFNDMGILEFAKTQHKMLNNMKEEINSSAGNLKTIRDRAAPPHQNRYLPEYRQHPMASDSSSRSSFSVLGSSSTTGFSAVGSQASFSDSSRTYHPSDGDRRSTSPPSPHDEDEEEDDDVLDVDDSDERSPNRVDMDSLRHRGKGEYRCPYWRTCQKGGQNTNGGPKIFHRNCMYRQHLQKHSKPHKCQLPGCPNKDGFARKDQLVRHQQNVKHDQPLPLPGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKT5</accession>
    <name>A0AAD8UKT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_654087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362330.1">
        <property type="nucleotide sequence ID" value="XM_060510692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKT5"/>
    <dbReference type="GeneID" id="85394591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042110924" evidence="2">
        <location>
            <begin position="23"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="416" mass="45913" checksum="1A0639E5B4FACE48" modified="2024-05-29" version="1">MPPPSSLVLIFLLLVHIGAGQSQDDSQPIQPPPSADASENHLSWQSAFWALLALVLNTATQPCGKICGFPSEWGFCLRWSPVVCVINSLEALSCLRLHHHSKRTLVVAPHKYNTEIDISHSDVANLQRNTLIRIVAFILGPLLQATKLYACQGTFWVQFLASIYLTSFLCDELVLGLIWIAGPAEGRNRVIGLVEAVAGSRLRPPVHFPLLRLESDAAMDEDDQLRDSRTTLRQALAIIASHLLLGWFLVETITGAYMTHFHAVIFSMLGTAFLGSIVSGIFCGLRSYKKHQKMPQVFLDVLYGVGNVIWPTGLVLAIGEKCQGLAVIQANGIIDFNAKGSGSQWAWKIGMVLWTLEISRWARLHLTTSNRYGIPKPVDVILPLWASAHIVVALAMFNFAYDPSRTYKPAWTDVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULI7</accession>
    <name>A0AAD8ULI7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydantoinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_753353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363606.1">
        <property type="nucleotide sequence ID" value="XM_060514342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULI7"/>
    <dbReference type="GeneID" id="85398240"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.390.10:FF:000002">
        <property type="entry name" value="ACR027Cp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1610.10:FF:000001">
        <property type="entry name" value="Hydantoinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="1">
        <location>
            <begin position="209"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="3">
        <location>
            <begin position="568"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="4">
        <location>
            <begin position="732"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="975" mass="104015" checksum="A3F42224B52BE5F1" modified="2024-05-29" version="1">MASQTRHLRIGVDVGVTNTDGVVLDPSRASEPGKGIIAWHKSPTTTNPSEGINNAIVTMFESTKIDPSEIASVTIGTTHFVNALFERDAARLAPVAVIRLTSQFSKHDPPCLDWPEDLRDLILGYYALCKGGLQVDGTLISDIDTEEIKAQCAPHRHERQEERAADIIRSEISSCTVTCSRDVANLGFQERENAAILNATEPMKRLGLNCPVFISQNGSTILSGEMAANLPFRTFSSGPTNSMRGAAFLVQDHELSNSAVMVVDIGGTTTDVGLLQANGFPRQQAVYSEFAGVRLNLSCPDVKSIGLGGGSLVRKGAEKLTVGPDSVGYRIKTEAIVCGGCTLTATDCAVLASSSSPAAPIGDATLVQGALDAQGVAQLPAIVKQKLEKVIDTMKTSPEDIPVLLVGGGAVIAPYELRGASEVLKPEWAGVANAIGAAIARVSAIVDTVKSTESKSVQEILGGVEEEARKKAVAAGAVPSPVQIVDVDTIPLAYIANKSRFIVRAAGDFDFSRTDLSSVLQSSEEGSQGDEVSTNRVVKTTAIRTKEEIDVLTYKPLVKDRVWYINETDLDWIRIGCYILGTGGGGSPYSQQLILREKLRKGAVVRVVNPHHIPDDALVGCGGHAGSPTVAIEKKSAGEMQKAQEEMYKHLGTPATHMISVEIGSANGLQSMMIGSSTNMNIPTVDGDWMGRAYPTKWQTTPVVFNERRPIWTPVTMSDGNGSIVTMSRASSDKQVERVMRAALAEMGSQVAVADPPVTGAETKRWVVEHTISQSWRIGRAVAEARKLNSVDNVAETITEECGGHGSAKVIFKGKIVGVDRVLRKGHVYGELVIEGADISTSRETGQEPKKEKFTGFVKIPFKNENIAAIRATSAKSGPQEVGTEKQEDVLAIVPDLIAVIDAQNGEAIGTPEYRYGLLIIVLGIAASDRWTSSTRGLEIGGPGAFGFSHLKYHPLGIIVKPRSVVDEFNVEVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMZ8</accession>
    <name>A0AAD8UMZ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364995.1">
        <property type="nucleotide sequence ID" value="XM_060508247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMZ8"/>
    <dbReference type="GeneID" id="85392146"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996010" description="Cell wall protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="14082" checksum="DA37D57C79E29E93" modified="2024-05-29" version="1">MYAQQVLVTFLMATGATLASARSIERRQLLGNLGSLSCNVARLQILGALGNTEDAVSQITDTTVQDAANAGLQQARGGIAQIAKSIVSGDAPPAASRDEVAAGLAAAGTALSGGDASDQAIADAQAGLDKSVKAGQDVVANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN01</accession>
    <name>A0AAD8UN01_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RlpA-like double-psi beta-barrel-protein domain-containing protein-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_578498</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364593.1">
        <property type="nucleotide sequence ID" value="XM_060505128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN01"/>
    <dbReference type="GeneID" id="85389027"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="4">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="28447" checksum="EA697308F41D68C3" modified="2024-05-29" version="1">MADEEQGIQRPAQTYQTPDWETPTANKRRSFFDRFAPATTGHQRDNGTTAAPTATNEGGFAKEDTQRSDDHAHLTAPATGAAATTGATAAPKARPSLAARFDALLPPHKTYFGISRKRFLLFIVLPLAVLFLLILPLALGLGLSKRGGGKQDLPLPNNQDVHTGDLTYYAPGLGACGKTSSDSDMIVSVSHYLWDNVQSGGNPNNNPLCGKKIRVRRDGEGSVDVTVVDRCTGCAPTDLDLSPAVFDKLANRDEGRVTGTWSWLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN22</accession>
    <name>A0AAD8UN22_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_581047</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4 7"/>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363410.1">
        <property type="nucleotide sequence ID" value="XM_060505417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN22"/>
    <dbReference type="GeneID" id="85389316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08998">
        <property type="entry name" value="GH43_Arb43a-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163671" description="Arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate recognition" evidence="8">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR026534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR026534-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1723355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="318" mass="34002" checksum="E730EB8B05922C1D" modified="2024-05-29" version="1">MAPTWKGLLGGLLAVLSAIPNVSAAYPNPGAVSGSVNVHDPSVLKTSSGTYLMAHTGTNIALKTSTDRTVWRDAGAAFPNGASWTTAYTGGDTNLWAPDISYRNGQYYMYYSASTFGSQKSAIFLATSSTGASGSWTNQGLVIESSSSVDYNAIDPNLIVDASGNWWLSFGSFWTGIKMISINPSTGKRSGTNLVSLARRTVNDGAIEAPFITRRGSYYYLWVSFDFCCKGASSTYRTMVGRSTSVTGPFTDRNGVSMLNGGGTEVMATHGSIYGPGHPSVFTDADADVFVYHYYNSANAALLGINLIRWESDWPVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNI8</accession>
    <name>A0AAD8UNI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_625868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363605.1">
        <property type="nucleotide sequence ID" value="XM_060508517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNI8"/>
    <dbReference type="GeneID" id="85392416"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042024888" evidence="1">
        <location>
            <begin position="27"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="17360" checksum="FF1767E0EFB0C359" modified="2024-05-29" version="1">MRRVTQVHIQWLACIHAGLHWTDVLARAFSLFSIFPAYRVDAPLIKLKCQTGLSITAVRFVHDAVYSIVDVVCDPDVLPNTRDGKIDNPMPLLGELCPPLPPPFLPPFLLPFLSPPVRTTRRLDQPPEDNRKAGPCSICSLVFSPGLKVKGVIWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP77</accession>
    <name>A0AAD8UP77_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_575702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365805.1">
        <property type="nucleotide sequence ID" value="XM_060504841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP77"/>
    <dbReference type="GeneID" id="85388740"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000326">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.150:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="359"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="53099" checksum="1ED7767152537DE9" modified="2024-05-29" version="1">MSLEPPTYLASLQNNIRQRPIPWDGAVRAGTITEDHLARIRAVDKAKKPEARKEIVEGDLDGYRSLFVGESGKPSVLESAGKQANVVQYILVLLADLLPSVPSLSKAIFKNTDPYKHFLPLLAHSNNTEDPIPLLTSTALTKLMSLSLNESQATRNAIPVLLSYLSGLAKSSDAGLQDIAVQEYSSILYGHAARQQFWNQRSETIAPLIDILRTAAGIGSNGSSSASIWSGTAPTRNAGFEGSLGGGVGLQLLYHVLLVIWQMSFEAEDIGDELNDEYDIVLLYTQLLRLSPKEKTTRLVVSTLYNLLNKNQKSLLPTAVLARLPALLDNLSGRHLTDPDLLEDAQSLKELLEEYTKTKTTFDEYVAEVESGHLRWSPPHRSQVFWAENARKILEHENGAIARQLAEIMKKPWENDKAVLAIACNDVGALVKEVPEMRYKLEKLGLKTRVMELMGESDENVRWESLKALGGWLKYSFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPC1</accession>
    <name>A0AAD8UPC1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_285128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365880.1">
        <property type="nucleotide sequence ID" value="XM_060502159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPC1"/>
    <dbReference type="GeneID" id="85386058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="48748" checksum="C405910AC7C2CF06" modified="2024-05-29" version="1">MADVLLDLLDARQSTSPDADVNTLFNPTTRATKLAYLSHLADQSPEALASTEPQSLAQTSHSLLLSLQGVSKRSHKSIIDSASNHTGLTHALPTLVADTADLRNAIPKLESEALRFSTTYSKSRDNEDLAERKRALLLLRNVERLVDVLELPTLLSSAINTVPANYASALDLNAHIRRLHGLYSSSPLVDLVSHQADEAIVKMTADLIAALKSPGLKLAASLRTISWLRRVVPDMSSMSSTNRGSQEHTLSLLFLCCRVATLDATLGALQPLRELADDERQRQQSANHQSWSGGQQTEKYLKRYVEIFREQSFSVVSMFKSIFPGTGYQTGTTNDDENPFKPMPSTLSTFPLHLVEMLLETLTKYLPVVKDQAARDSILTQVLYCSGSLGRLGGDFGMLLATLGGEHEETKQTEWVDIVKRHRLLSGRLESVIGDFKATGAKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPF0</accession>
    <name>A0AAD8UPF0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_621897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364834.1">
        <property type="nucleotide sequence ID" value="XM_060508295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPF0"/>
    <dbReference type="GeneID" id="85392194"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="494" mass="55916" checksum="6A1033F93C6A34A5" modified="2024-05-29" version="1">MSSAHVDKGGSRRLRLFMPADGPNINLCKTVMSAVALGYPMPTLLNWDGEFNRPDWHFAGSHIAKLESLLAVIDALYEKNDGDDVNENDLILLVDAYDIWFQLPPSVLIERFHQLNRKANIRVQKEWEESGLKSGFPISPPTQNIIVTTAKDCQPDWESGSDPRYDYWPDSPLPRDFYGEKTDQVLPYVFDSARKYKKIRPRCVNSGMIMGTIGSLRGALRKSKEKIEKAAVSGRQLWSDQALFAEVIGDQEVHRHWVRGLSSTWNGFVSQENLGSMPKEVRRIANAALAGEKFEFGIGLDYEFATIPPTCSSEDDGYFVNLDDAEAIKRESEKAGVPGEVRVQDIPEELRDASRPLPGYSWGNVSLYTDFFFGTAPVGIHHNAYIFGLKKWRLENWWSLTWFYPHLRDLVVQALDANRKLMPLARLLTRSDSGNEMVYWAAEEEVNGKKSLRVYDGSKKPGDFSFIGWEGICQKGDEKWHNVLFGDGKGPLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ87</accession>
    <name>A0AAD8UQ87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_618268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365808.1">
        <property type="nucleotide sequence ID" value="XM_060508068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ87"/>
    <dbReference type="GeneID" id="85391967"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000010">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="37216" checksum="7BACF65D177416CB" modified="2024-05-29" version="1">MSYFFSTPVDIDIVLEDADERSMVDVKLDKNRREKAPLYMDGESVKGAVTIRPKDGKRLEHTGIKVQFIGTIEMFFDRGNHYEFLSLVQELAAPGELQHPQTFDFNFKNVEKQYESYNGINVKLRYFVRVTVSRRMADVIREKDIWVYSYRIPPEMNSSIKMDVGIEDCLHIEFEYSKSKYHLKDVIVGRIYFLLVRLKIKHMELSIIRRETTGAAPNQYNESETLVRFEIMDGSPSRGETIPIRLFLGGFDLTPTFRDVNKKFSTRYYLSLVLIDEDARRYFKQSEIILYRQAPDAAAGPNMIMAAAPENPKLMGQSVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQF4</accession>
    <name>A0AAD8UQF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_749382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368146.1">
        <property type="nucleotide sequence ID" value="XM_060513760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQF4"/>
    <dbReference type="GeneID" id="85397658"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034431">
        <property type="term" value="F:bis(5'-adenosyl)-hexaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034432">
        <property type="term" value="F:bis(5'-adenosyl)-pentaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008486">
        <property type="term" value="F:diphosphoinositol-polyphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901911">
        <property type="term" value="P:adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901909">
        <property type="term" value="P:diadenosine hexaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901907">
        <property type="term" value="P:diadenosine pentaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071543">
        <property type="term" value="P:diphosphoinositol polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04666">
        <property type="entry name" value="NUDIX_DIPP2_like_Nudt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047198">
        <property type="entry name" value="DDP-like_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="161" mass="18438" checksum="75154861CBD0A527" modified="2024-05-29" version="1">MASSHKERTMESRTGRSKQRYNSKGERLVAGVVPLTKDKRYVLLIQSTRRKGWVLPKGGWETDEECTEAAAREAWEEAGITIEIDYDLGDIVETRAPKHSSKDSAKALYRFYEATVTAQEEAWPESHKRERQWMTYAQAKDALAARPELLEALTRCTMKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URG4</accession>
    <name>A0AAD8URG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor PAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_718779</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the bZIP family. YAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366051.1">
        <property type="nucleotide sequence ID" value="XM_060512110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URG4"/>
    <dbReference type="GeneID" id="85396008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000067">
        <property type="entry name" value="BZIP transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="157"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="574" mass="61801" checksum="669DD3EF3B5B0849" modified="2024-05-29" version="1">MASTTNSGFPTNFILTPQQQSLLYAALNSNKQQLANQSPTTKDNSMSPSSYQTSPAQGAAATGFQESPYLDNYDYDFGDSSFDFDVSTVSQAKMIGDIPGGAQSAKSTKSDSTENDGNDKRSHPDDDEDEDSPGNDAKRREGSEKAPKKPGRKPLTSEPTSKRKAQNRAAQRAFRERKEKHLKDLETKVEELEKASKDVNSENSQLKAKIDRMTSELNEYKTKIAAMSTRSVSHSKSPMGFGNSAIGNLSDVNFQFEFPKFGVLPGSQMPTKPAQPARSSSSPLQMNGSNPVSPLNHTKDNSPGIIAGLDFGTKDDLANFTSLFSPSLANGSLGTNTSRASVDSGSYTMNNGTSTSSPSASSQSNGGPSSSCGTSPEPFTQSPMGFKPVDTMTTIGEESTAQQSLFAGIDTNNFDWLAQQNGGQFDPQLFGGYREPQENILAATTFDESFFNDALDADFITPYNMAPSPNVPKKNLIDQIDAAKNADDDVVKEAVKAENYNCNKIWEKLQTCPSVQAGEFDLDGLCSELQKKAKCSGQGPVVSETDFQTVVNKWMGKDAAACFSNQEKNTQAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USC0</accession>
    <name>A0AAD8USC0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_614635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367049.1">
        <property type="nucleotide sequence ID" value="XM_060507847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USC0"/>
    <dbReference type="GeneID" id="85391746"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="286"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="57406" checksum="55E509533BEE2594" modified="2024-05-29" version="1">MDQTTTTTASASATENTPLLPTTELRPKSSRTVTFNPNPVSKTIEPEPNFQRSKSSHGNSLATSPGQSSALSSINSKLRRRNSHGAVQSLPPQMVPKIGPQRSTKNAQKLKLLPNPELNEESPDEESGRDVYSQYTRIKDPTARRDAARLGKADRDRLPRVTAYCTANKYQMEGLMRFLKGRGKSRGANPKLIDECIYTAYDYSKTVENRHDRRVGAQPDPVQAYERRHSTGDVSDNGFARDNLIDLQSEGRHDSGFADGFEGANNEHAMVETNPDFDTQIHTPEVFLFDYGVVVIWGMTLAQEQRFLKELAKFETEKLSPDDVETEHFNFYYTKEYQARIYNDFITLRDKRNYMTKLAISHALAQSVKTSLFEELIASTVDTCKDIPTQIALTGKIALSRTQINMQIGELFILRINIHLNGSVLDTPELFWVEPQLEPVYQAVRTYLEMDQRVGLLNERLDVIADLLAVLKDQLSHGHGEKLEWIVIVLIAAEIVVAAINIVVDLYASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTD3</accession>
    <name>A0AAD8UTD3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_612713</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367473.1">
        <property type="nucleotide sequence ID" value="XM_060507727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTD3"/>
    <dbReference type="GeneID" id="85391626"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058758">
        <property type="entry name" value="UBA_RNF216"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26112">
        <property type="entry name" value="UBA_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="297"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="683" mass="76316" checksum="FFA990CDD1F66C5E" modified="2024-05-29" version="1">MGLTTFLGSSTDKLVSSRSKTSSSSSLQKASENASSQTTDAGYTSASASSSHHGYIYDEEQLPALSPDCPDLRELNNSLEALAAIFPDIQIQVFREMLINFDEESRLAVVIDALLKNRVAWVKGRWRTVENQPARPLVANEQAGEQDDEALIPRVEAFRSPEYKHAVQALAWHEFKGLSRSTINAVLAESNYSYLEARNTLVSLSSKSWRFTISSLFLRRKPVATGEAENHPLIIWKSTGQGAIVPSLKATGNAELDSELYRDLVRPLKDRARQTQEDKDRGLAFLMNNEEAEEAGAMHECACCFTESTFEEFTTCSTDGHMLCFRCIQHSIMEAVFGQGWHSSIDTNHGTLKCLAVEGNGCPGHIPYEHIHRAMLEEKKGAEILRKLDQRLAENSLLASNMPLIRCPFCDYAEVDDIYLPAQETQLRIRLDSLLSLALLLVCIATVPFLLPVVLLSSFLCLLVSTKQTVGDRLVSHWHLALGRHRRRRRGLKFACQNPECGKSSCLSCAKAWKDIHVCNESSLVALRTQVEQAMSMAIKRVCPRCHTSFVKNSGCNKLTCPCGYKMCYVCRKDIGGTNGDGEGYRHFCDHFRPDGDPRPCTECLRCNLWESEDTDSVLRQAKEDAEAKWRETEKRELNGAEKAFLETGFARNGVSPVENRLKNGQLPTLPELCDFVVETVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTM3</accession>
    <name>A0AAD8UTM3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_770338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367589.1">
        <property type="nucleotide sequence ID" value="XM_060515343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTM3"/>
    <dbReference type="GeneID" id="85399241"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF174">
        <property type="entry name" value="ARRESTIN-RELATED TRAFFICKING ADAPTER 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="469"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="848"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="918" mass="101419" checksum="8B09071100E64A05" modified="2024-05-29" version="1">MPATMTDSERSRRTENWIPTSTRGGVYYCPRYLLDPPATQQSRLPTPPIRARQVRPRSIHITSWPSGFVPHELRPQPERPVKRRKPSKAVSPTTTALGKTSLKFSIKQFFSLSQKQVPSRSTSRASTLSRPTLSRPPSRAASILNRLSTYREVDLVVPDEDTMALRSAAMSEALRPPLMSSTYNTPGQRNSLMSVRSAKSNVTSMVTEIPKPVAHGSGVSCSILMAEPNIFLTGFDHDGHRQHSQGGTALLRGKLQLKVTKNIKIKGVSLKLVGKARTEWPEGIPPLKVDLYEEESLRTQVLTFFNAVNDGWETEYGNQCVYTLKNSSTNSSSTNLASSSPRNSMSPSLLSIPPNRQGLTAKELKRLSLQSNQSRSFGKGDNPSGNQAKGYKVFYPGTYEYTFELPIDHHQLETTKLQYGSVKWELQATVERAGAFKPNLHGSKEVAIVRVPDQLSLEMTEPISISRQWEDQLHYDIIISGKSFPLGTKIPIAFKLTPLAKVQVHKLKVFVTESIEYWTNDRRVTRKDPGRKILLLEKTAGKPLDPAYASSDVRVLNGGELTPRQRREARESAAMRRAADASRHGVMPEPLPEPVDNILGDLDLGLESYWGSTEIEMNVQLPTCETMAKSKEMRLHPDCSWKNVNVYHWIKIVMRISRLDPEDPTGTKRRHFEISIDSPFTVLNCRATQANTSLPEYSGPDVGLNQSRHTSCGCPDAVTISGPSEGSPNNLSTGALTVMEAPGNLPAPPQAAHLPSSPQPTTGGTGRSSPPNSQTSVDPLADVHPRPIHLLRVPSYNPPAFDAETPPPPAENDQLPLQTPPPQYDVIVGTPSVDGMADYFARLADYGYDEPEEDSDSDEGPARITERGGRVNVAHPRTPGGRRAPSRSMEIQRPPVELRMDALPNLNLRRDGVHPQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTN1</accession>
    <name>A0AAD8UTN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_617195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366170.1">
        <property type="nucleotide sequence ID" value="XM_060508015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTN1"/>
    <dbReference type="GeneID" id="85391914"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="64" mass="7292" checksum="FBD8B9DB2535640B" modified="2024-05-29" version="1">MPRPNEQASRSLSNERDTRRSGPDSATDSQPWDRVPTFAFHTPMSLRALRRRKADITARPSIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU94</accession>
    <name>A0AAD8UU94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_749665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367923.1">
        <property type="nucleotide sequence ID" value="XM_060513794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU94"/>
    <dbReference type="GeneID" id="85397692"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="134" mass="15007" checksum="55986DCE45D0B5B8" modified="2024-05-29" version="1">MSFYEGDSRTGPQPAPPPRALTAGEIGAIVGTVIVFIGVVGALFFYRAHKAKRRRAEHGERVDDDDDDDDEHRLHETRHHKGDDGLFQGGGRVVTKPLPARKKTWDPYEGAKTDESDAERGESHEMRTQERVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUA1</accession>
    <name>A0AAD8UUA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_179511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367938.1">
        <property type="nucleotide sequence ID" value="XM_060501516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUA1"/>
    <dbReference type="GeneID" id="85385415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="69626" checksum="24986D7D51BC9257" modified="2024-05-29" version="1">MLLASGQGALGHGLSDHAKRSIDQTMHMSSKRALDGFYVIDQQAGSEWGCSEEKIAALEGAVRDTQALAFMASTVLAEKDSEFSDAYIFWFGEDNTKAAVKNSIKTLNYDPVQDFLKAPGARNRVDDMRIDNLSPTGLTYMCAAADDSMCAGGMAAAAHQHGAGGLSGHSIVLCDRFFGANSQQDMLRTWKDTRRLSASSGFWLLHEVQHLGAIVSDGRRCVDVPDPNETDGSGCYDANCCSRLKGADKIRNAQNMAFFALEVMADPQSGAAPGQSCTIMKRDTGSVLLGGPEDLMARADYSPDAKYEAMLRRQAKPSSTWITTHRNSTSSRVLTAHSSKVPVPSSKKPTGSASASRSKPPVPPASSGPQSINPTQPSSSGPRASNPVRPSSSALQSSKSAPPPSSGPRSSSRGPVFTTRPPVPVSSFSGASFSYSYSTAPPTTEEGGVPVDPIVPIPIPIAPVAPVPPVVPPVGGGGNGGDNGNNGENSKPAESNPPKTSEPSTPPTSLPPTSSSKPSPTSSTPVTRCSSRPPLSVPTGGDASPDRDGFPQAVYDGLAAEARSTSRASSSSSTSSPLMVITDVPEPETTAEVVPTATPTAAPVNPVACYNFDINAYGYCCPGPGNPCERDIGKCYFNGEGVSGGASGIVPDGARCPPPPGAEYCRGPCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVN3</accession>
    <name>A0AAD8UVN3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_228151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367190.1">
        <property type="nucleotide sequence ID" value="XM_060501789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVN3"/>
    <dbReference type="GeneID" id="85385688"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000001">
        <property type="entry name" value="Fungal specific transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374:SF1">
        <property type="entry name" value="FLAVIN PRENYLTRANSFERASE PAD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="779" mass="86254" checksum="9D81B7CFB0559873" modified="2024-05-29" version="1">MTESQTTPTPDQASIDDLTPEEANRIIHSHRKVRYGTACWPCRQRKVKCDNKQPCENCVKREHPQLCSYKPNRTASHGTNHKAAGSVTTEGGNSNAGGNGATTTTAPTTAGNGTASSVLNRKRPHSPEDPAADAAAGQPPLKQEPGSATWPRAAIGVVDETEAPEAVTRYLGQNSIPSLLREQSGANELQEGVDIRQDMRSILGLDTSAPFPLMSSKHLDSLTREISAELPSDREVMKLFRTYKETPQQFWGFVVDIDDLESKLMVYLEDRARNASNAARTPKPVSASWLAILFALLAVGSQYHDSPYHIRTRDSQKYIQISFHFLRLGNFLLRPTFDSIQALLLTSFVLLNDMKAEASWALLGLTCRLAQSLGLHRPNPSDGRDSARNDGQSKEMIRRKLWWTCVWHDTLTSLSFDRPPMTNIPCCPIPTVATTIAGEYGYLDTMYHLCEIISRRLNPDVATTVSYEQMVENCEAVENLRNNVAPNIRIKEQCKRAIDRLQHYAVRLHTSFVISVCCRPALRRDCTKLTPEQKRHLSDKCQHNLAETVRMFLAMHQLSVIPTRSWAFTYHGLSSALLLGILGETKNSPEVRQLQGDLIAALSATAAKEATSPTAHIPKTDKDIELSGPLWRALTALRNIYEHGTIMGTSQMKGTDSSGTGSGARTPLPPMLMGPMGNNVNGNNDGKPFGMDPHQDAALAMAEMQNGTAMTEYTPNMGYPPVSMDNIANLDPSTYMSPMDLYESIWWESPDPWNSGVDTMNFDFVAQPPPGQPQQQFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXH1</accession>
    <name>A0AAD8UXH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_664919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368300.1">
        <property type="nucleotide sequence ID" value="XM_060511084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXH1"/>
    <dbReference type="GeneID" id="85394983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="61373" checksum="4BE468D75AAE7421" modified="2024-05-29" version="1">MLVVKDIAFGIMAWTRTPRTTAYRKLNEIDAEAFRSPGPYDKPSFSHRLQRTSPKALVKLIVPVFLFSGLLYGISRTDITQYIPDSNRNALSSLPPLEKGGQRRLRIIVPADGPSPDLCKMLMSSIASGYPSSVIVNWGRDFQKSPGWFGGSHLGKIDGTLEFLDSITSEEAPDDERLGPDDLVLLVDAYDVWFQLPPSVLIRRYMAQNYAADERTRKDWVGSRSWFSLNSKNSLVPRQSIIISTQKKCWPDASLGSDPHCDDLPESSAREDMYGPHTDEDPKQRHDLRPRYVNSGSLMGPVGDMKQIWRTSKRQNHDEWVKLQADHPTKAAQELQQNDFSVGLDYIQDLFTPTVFEEDDGLYIVSLDGPGLRQAAADRGIDPPRVTGIPEDILGLRSPIQETAIDKNMAWQDLPLYTDFWSTSVPVVVHHNAHRNGLKGQRLRDWWKNNWFFPYLRSLLELHSKPREALEPLFRAPGRNGVEDLVYTAPASDAQKRKPRIFKKQDLKEQGLAEADWDTLCKSEGHDEWWNEVLQDGNGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9K9</accession>
    <name>A0AAD8X9K9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_712605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358151.1">
        <property type="nucleotide sequence ID" value="XM_060511617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9K9"/>
    <dbReference type="GeneID" id="85395515"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1707935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="646" mass="72532" checksum="5D64F13FB8643F13" modified="2024-05-29" version="1">MATAADIGVGVARLSKACTECHSRKVKCDAPVVGIPCGRCASKGYYESCKLVSRQIRKRESLSNHAVVDSPGLSTRRVQRSSTRHTHGPHGLGELGKTSSIGSGRTPENIRDVYALPQAQAEYNGRSHYLNILKTAMNGSQTSESPGLGSTANSSTDNTPHYPENTQVGMSGLDPVDLEFLMKKGAFVLPHRDTLMVFLTAYFRFVHPYSPVLDPSHFLQSYELGSYSPFLIQTVLTSATLYVPTDLLTSCGYSNVTEAQTAFFNKALLLHDFQCEKSQLCLLQGSLILGTTAFFYPIDRDVQYWFFNAVRLATKLELQKLDQLRIADAQLRGLYRRIWWVIYCRDVLLSFLGMQSMPLVSYKKKLPALPTAEDWEVQSDEMHALFSLALTREQELHFIDYCNLSVLGRKWLVGISDPDQVNAETMAHEFHDWRSQLRGATYADHHLTDGPYLTALIAASYRFECILYRTLKLHWKSVDVSRHDWARGRLRCSMFELDTLFGRALANGELGSLPMSFNSNIPIALALHIETALDAVESNATKSMSLIYIRQGLLILEQLQDLPVMKRILSIFEWALNRLDLIPEASRDKQLSDGIHAGMVQDGSVDQMGASTDHEFGEMLDQMEPWFGDFLVLDFIDNLRSSGDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAI1</accession>
    <name>A0AAD8XAI1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_655932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360142.1">
        <property type="nucleotide sequence ID" value="XM_060510832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAI1"/>
    <dbReference type="GeneID" id="85394731"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="284" mass="31372" checksum="8A6A4B766FAF6567" modified="2024-05-29" version="1">MDFVQNPTYLLAPQWTFRPGGPIAIGNIIADPFKPHIVCSYADASSNAYATDMAGERNWRMSQETARRFDVSMWSVFLEKIQLKIGASRSNVRHGEYTMDVLETTYLLRHPSHEEIHERCNSPAVKPLMNMERIKAKPVYMITGLKIAKGFAVKQNSSSDKAAHAQAGAEVSPGVSVGAEVSGSKSQREHHGFEAMQDIIFGYQLLKIEPKGWGKRKQLHYGEFMKRKKSGIKDPESVDGEASLPAAGEFQEMGTDIQSVTLDDGDAGHGAIVFQAPDEEEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBC2</accession>
    <name>A0AAD8XBC2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_585524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361449.1">
        <property type="nucleotide sequence ID" value="XM_060505854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBC2"/>
    <dbReference type="GeneID" id="85389753"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1719365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="149" mass="16851" checksum="A3D8A3FF2DCB7BD5" modified="2024-05-29" version="1">MINLTRASLLEKEHWDNLLPLSPTIHVSKISTDGTHRDPLGAVKERREDQPCVSVHLCTEKDWKGDCWWACFRDGLETYPNCDWGGKVKSARPGEGAMCKFFFDPDCSMRTKRQDMKWPGGNFEGLGDFGVGCFYCVMEGSKKSYSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBE0</accession>
    <name>A0AAD8XBE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_198856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000230">
        <property type="protein sequence ID" value="KAK1706127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357775.1">
        <property type="nucleotide sequence ID" value="XM_060501647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBE0"/>
    <dbReference type="GeneID" id="85385546"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="61" mass="6575" checksum="FCBD96C68485D181" modified="2024-05-29" version="1">MRASHYLEVPLSAVSMAYWTHLKQELLPLGRRGMAWIITSVTALSVIESAGVCDASIASGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBZ2</accession>
    <name>A0AAD8XBZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_765893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359003.1">
        <property type="nucleotide sequence ID" value="XM_060515258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBZ2"/>
    <dbReference type="GeneID" id="85399156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF35">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1711200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="32137" checksum="FD6B9DD6E8FDA618" modified="2024-05-29" version="1">MDGPPSKYPYDPSLAAAVTFAVLFGISGVIHSFQLKRAKTWYWIAFFIGVNFESIGYGARAMNASETPNWSQVPFIIQTLLPLLAPALYAASIYMLLGRTIDSLEAGHLSIIPVRWLTKIFVFGDVFSFAFQCIGGGILSGASDKDGLDRGQNVILVGLGIQILFFAAFIVTISVFHSRIINYPTTMSMNGRRPWRQFIMVLYATSFLILVRSIFRVAEFAEGRDGVLQTTEVYLYCLDTSLMFLCAAAFNVWFPGRIVSPITFKDEERFPLGAVSNQDDDGVFRIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDR5</accession>
    <name>A0AAD8XDR5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2406 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_579630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364074.1">
        <property type="nucleotide sequence ID" value="XM_060505264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDR5"/>
    <dbReference type="GeneID" id="85389163"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018809">
        <property type="entry name" value="DUF2406"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28186">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28186:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10295">
        <property type="entry name" value="DUF2406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="47531" checksum="7400D1D46E026D7E" modified="2024-05-29" version="1">MAEHHPLPALPPQHQQPNHHYHQQGPDSYDNEQSQFPPYQQHYDQPQPVQPPPNAQAQSQSQNQPPHRRSKSRPRTFSFQSNKSHKSSGSHPKIDLHETPEEKEAKRLHSKADPTVAMSEAEPSAVQAMTKTSLAPLRAIQHKDTTGAPIAEPDRSNPTRSRWERPLDTIRSFEAAIDGGYRDRDRRQSYIRSDTESVQTWNRRSSYYATSGGRHPHDSYYNGRPGSFRPESGQIEMGSNRQSYYDQYQNGGGHYNGGNNIPYRQRVPRTQTDPHMNGYARGDQNIYPLPNKDRSYETVTSAAASGSSGEHAGYHTDPTSSDNSSIERGGQGRRPEPTNDYGIGFSQDQGYQASALKFDNGAPNGKGHAYQAVNNGAQVSQQQSANVLRRPVGASAPQQQQQAQPRPAEPAKRKSWFSKRFSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDV2</accession>
    <name>A0AAD8XDV2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Na/H antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_586009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361148.1">
        <property type="nucleotide sequence ID" value="XM_060505904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDV2"/>
    <dbReference type="GeneID" id="85389803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="6">
        <location>
            <begin position="70"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="50207" checksum="04695B70743C0350" modified="2024-05-29" version="1">MDLSITNFNVVISVLGGWLVLFGTFSYLIKENLYLSEALVSLLGGVTFTHVAKLLKPGEYAVSEDAVASVTLDFSRLVLGVQLVLAGVQLPSRYLRTEWKSLCLLLGPGMIGMWTCTSAVVWLIVPGLPLVHALAIAACITPTDPVLSTTIVKGRFAEENVPEDLQQIIVAESGANDGLGYPFLFLALYLIKYTESDGNPASSEGGFGAALSLFFGQTCVYVVLMSVFYGWVVGLLAQRLLHWAERRKYVERECFLLFPIGMAIFILGTCGMVGSDDVLACFIAGNVFTWNDWFRLETVEDPVQPAVDMMLNMAIFMWLGAVCPWESFWNSELISPGRLVALGVLVLLLRRLPVILGLHRYIRQIRGPRQALFVGYFGPIGVSAIFYLYVGLEFLETLTDDDGQRADAKQLGETMLVTIWFLIICSIVVHGVSVPIAKLGKSTYERFFPRSVSLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE39</accession>
    <name>A0AAD8XE39_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_581923</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363011.1">
        <property type="nucleotide sequence ID" value="XM_060505502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE39"/>
    <dbReference type="GeneID" id="85389401"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="48"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56228" checksum="84512349CB707717" modified="2024-05-29" version="1">MYESEPQSNSTKTRSLEEIEHVDQSLEVGDNPPSVYLAIRVYPKIVGYTLGLCIAVLLFGYDNVIVSSVSAMPGFQIAFGDYHNDELIIPSSWLGVWTAASPIGLVFGAAAGGWFQNRYGRRMSLLFGNLVVALGIAICFVSNRIDDKGGRRGVYLVGKLMEGFGVGTLVCATQTWISEVAPVTIRAFLLCLIPTFTLFGQLIGSGVVFALLAAPADLSYTIAFASQWPFSIVLFPVALLLPESPVHLIRKGQEDAARKAYERLYSARDAADAIETFKYTIQHERASNGGRSGELRDCFTGHNRRRTWLVLFSYNVPQFFGITLLANASYFMQTVGMEASQSLMFLVIGIGIGIVANLLSIWTLARFRRRTLLVTTLFVTVLLWVSVGIAGCFVDSSAAVWYIAACMMVIIFVCGCGAWPASVVVASETSSLQLRGFSQSLGWLSQGVVSGVFSIVLPYIYNTDEGDLRGRTGFILAVLAAAACVISWLCVPEMKGLTTEDIDLKFEQLMPARQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE54</accession>
    <name>A0AAD8XE54_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363937.1">
        <property type="nucleotide sequence ID" value="XM_060510548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE54"/>
    <dbReference type="GeneID" id="85394447"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="30313" checksum="90E6671272AE87BE" modified="2024-05-29" version="1">MANIFRQAISWLYTTLAVSILGSWTLLILGGVGLTAVDSNPGLLQLIAFPSLLTFLVAKLIVAATPSTALQQQPQANARNTLAAPAPTGGAGGNLATWLATADYGSPHGALVLFLFSVTWLLQLARVVFALFLVVLMGAFFLFASSLDAADKEDKEAGGEGLFSDDDGARKNFTTALAEFEEKAGIGLGDYLVDNPWVVFQVFVALWGMMNLLLMYLFMYAFGALKKVLTTPLEAWARGGQEAAPAPAVISGRSPPAAAVASAAETRAPVVVVEKERVVVPAEAQPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE87</accession>
    <name>A0AAD8XE87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_345489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364599.1">
        <property type="nucleotide sequence ID" value="XM_060502484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE87"/>
    <dbReference type="GeneID" id="85386383"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="145" mass="16452" checksum="D4BA0A9D7C688AE0" modified="2024-05-29" version="1">MATAETVDLGAVHAPKEESIKVFQEIAHDLKRELLHIRREHQKHEPEYFQAVEHLDDHQLAAFGPDNFVAVRVASSAYGIHLFGKVRIPALPESGPAYIHFRAFVPGAESPKLHSIHTEETDHSDGDKTYRAIFTKDDDLEWFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEA2</accession>
    <name>A0AAD8XEA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Intradiol ring-cleavage dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_631847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361613.1">
        <property type="nucleotide sequence ID" value="XM_060508927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEA2"/>
    <dbReference type="GeneID" id="85392826"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042051548" evidence="2">
        <location>
            <begin position="19"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="3">
        <location>
            <begin position="130"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1719529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="386" mass="40529" checksum="130E802DE0140FFC" modified="2024-05-29" version="1">MRFSTVASGLALLSGAVAHPGHDLTEEIAERRAFLSTIKRSNLAHCADKLAARGVTARNVARRSAQLNQARQKRNIKRDADTVLAESHNSTDLGYTLNTDAATLFSGNNSCVLTPEVTQGPYYVSGEYVRRNIIEEQEGVDIVLDYQVIDVDTCEPVPNVYLEMWHCNSTGVYSGIVASGNGDSSDETNIDKTWLRGIQETDSDGVAQFESIFPGHYTSRATHIHLMVHQNATLYSNNTLGNVITASHVGQTFFDQDLISAVEAFAPYNTNTQELTTNADDSILSEEAATDGVDPVMEYTLLGDSITDGLFAWMAFGINTTQAQTITPAASLYAEGGVANSNSGGGAGGAGGSPPNGTAPGGAPGASSSSVATTSAAASTDAASSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFH8</accession>
    <name>A0AAD8XFH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_751348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365964.1">
        <property type="nucleotide sequence ID" value="XM_060514040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFH8"/>
    <dbReference type="GeneID" id="85397938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="55203" checksum="839568D622E2DBCD" modified="2024-05-29" version="1">MTEAPENLSASLLGNRLSSRSVSTSSNRRQPVDSLVISLDELSHHSQDPVDAVPNNPDDTGSGASRLSRETFAQSQTVATDERPVSQIRCPKRKFEFFVFLTDCAALLSTLGLLVFGLIVWRSDGTQITEKDRGTRVNTINVLATVFPILFASVVDRLVSEAARWKLENGATVRSLEQLLGSRTVGAAALTLVQFRSFNILSIMLVFLWAFSPLGTQSLLRMNTSRLEPSMKSTSLIYFDSGARSQLADWGNSEVSGSSVVYTYSKFRSLATLYTSLVAAPQQIKDDNMDIWGNVKIPFFNGVDENWKNITSDTAQHPYSALAGIPLMHLNEDNATFSLESDYIHLECKNLTKIVRSVTPEDIREDLISDEGLKDFGTTYRAATNRSRLLNGTWHGYSPTRSSSTATTWSLALDRFIDPIWFAIRKDENGNESERYPVIRPDEAMRPILFQGESGIEVGKPTLLFQAASASSMHSPEGFIRAYYGVTQRYVESRVNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGC0</accession>
    <name>A0AAD8XGC0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_580204</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363818.1">
        <property type="nucleotide sequence ID" value="XM_060505327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGC0"/>
    <dbReference type="GeneID" id="85389226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="439" mass="49121" checksum="251DE29D62F57022" modified="2024-05-29" version="1">MTDQPFKVIVVGGGPSGITAAHVLQQAGIDFVILERRDSIVDDVGASLVLSPGSLRVFHQLGILENLMEIGNMLSSGTGFTSDGHKFKQNLIGDYMIKNHGAGLTTFHRAHLIQVLYDTLPESARARYFTGKKLADIESTEKGVTVTCEDGSTYSGNMIIGADGVHSATRRHMRKLALAEDPNRDWDPINPYKIQYQCLWASFPRPTDAGQGCETQSKDKSIMYLTGKERGWIFLYEKLTVPIPERISFTPEQLEEYAERFADWPVAENITVKDVFKERYSAGGAGLEEGICKNWSWGGRIVLVGDAVHKFTPNAGLGFNNGLQDVVAVCNRLQKLTANGNSPSPDDLQKLFDSYREERHVLLEKDLDASARLTRSQAWESTFDWIMARYIMAFSFVQKIFFTLNMSPSIQKAKVLDFVPAKEVFNGRYKWLTPFPSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGZ3</accession>
    <name>A0AAD8XGZ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_578611</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364508.1">
        <property type="nucleotide sequence ID" value="XM_060505145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGZ3"/>
    <dbReference type="GeneID" id="85389044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23284">
        <property type="entry name" value="beta-trefoil_MIR_PMT2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000012">
        <property type="entry name" value="Protein O-mannosyl-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="640"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="332"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="398"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="462"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1724453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="738" mass="83883" checksum="3919780190441EA3" modified="2024-05-29" version="1">MATEKPIVASGADVGDGVRRRAVPQGQSVPITAAPEIDDKKKLVKKQSSFLDQWEAIIAPVIFTTVAIFTRLWRIGISDIVTWDEAHFGKFGSHYIKHEYYFDVHPPLGKMLVGLSGVLAGYNGSFEFKSGEKYPEDVDYTFMRAFNALFGILCIPMAYYTARELNLRRPAVWLVTLMVLCENSYTTISRFILLDSMLLFGTVATVLCWAKFHNQRNDAFEPEWFFWLFMTGLSIGCVCSVKLVGLFVTSLVGLYTIEDLWTKFGNTKMPVTTLGAHVVTRVVGLIIVPFLVYMLSFALHFAILDHTGPGDAQMSSLFQANLKGTEVGKNSPLEIAYGSRATIKNMGYGGGLLHSHVQTYPEGSTQQQVTCYHHKDANNDWFFYPNRADADYDAEAPPRFIGDGETIRLIHAQTGRNLHSHEIAAPMTKSDKEVSSYGNLTIGDDKDHWTVEVVRDVASRDRSRIRTLTTAFRLRHPVLGCYLRAGNVNLPQWGFKQIEVTCTKTNNPRDSYTHWNVEAHWNEKLPPGDPGSYKSPFLHDFIHLNVAMMTSNNALVPDPDKQDDLASQWWQWPILNVGLRMCGWDDNIVKYFLLGNPLVYWGSTAGLGVFGLVVVWYLIRWQRGYNDLNSKEIDQIHYAGLYPVAGWFLHYLPFVVMARVTYVHHYYPALYFAILTFGFLADWFLRNKNQVFQYGVYGVLYATIIGLYILFSPICFGMTGNNKQYSYLKWFDSWRISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH24</accession>
    <name>A0AAD8XH24_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_405993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363145.1">
        <property type="nucleotide sequence ID" value="XM_060502875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH24"/>
    <dbReference type="GeneID" id="85386774"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="133"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="43227" checksum="D804F18DDCAAA8CE" modified="2024-05-29" version="1">MLQSKLTRTISNISNVSKESRASRKERKAESKVASKANSVASSIAGASDDEYDNPLENIARWRLTANAVALRSGAAFAFGLQNLSAPVPPAADRVIWLDSTLSEWAGKEKIRVDVYLPPTTSSSKPTGKIPAVINFHGGGFILGQGTDDARWAGAVATALNAVVFSVSYRLAPGYPFPTPVEDSADSILQIVARAEDFRIDTNKVILSGFSAGGTLALASWNILQDPNRWGYRFKLPVPDISGIVLFYPLLDWTMTRPQKRKTCGKPEMTLPKGMTDLFDASYIYPPRPRSERGDPRLSPGLMTDEMIDRLPPVHLCMCEHDMLLLEGQAFAERVRSRGRRVSTRVVEAEKHAWDKPPPFAPKETVMVEYNEAITAIEEWFDNTGMTWKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHB7</accession>
    <name>A0AAD8XHB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364868.1">
        <property type="nucleotide sequence ID" value="XM_060514162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHB7"/>
    <dbReference type="GeneID" id="85398060"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF4">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042005539" evidence="1">
        <location>
            <begin position="20"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="2">
        <location>
            <begin position="409"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="853" mass="91107" checksum="D5E2B7C939996659" modified="2024-05-29" version="1">MAVSRLLLALAASATGVVAGMSSRNSTTSFTAKGIATGTAAQLQTFPFTPFTLSPEIPMATLDYGAERAGYPIFEVSALSAPAQIEVKYTEHFDGLDHPFGDGPYTFSNQLSNSFRVETFNITSIGRVKSLLIQGGQKWQSIKLLTNGTVSFSSVGFEATIDTTEPEELPGQFESDDEVLNDIWKLGARAATAACFDKGTQKTIWEVSEENGVFARSTRPSVTYKGTAWSNYTLEFDTKIERGGSWWVTGGVIAGNGYTMLLTGELPESSTFANVNKTLTPPNTISLAYGPDFVNQTTLTSYLLDVFKVPFTVKEDEWYHIKASMAPTGHLAVSINETQILNISRSDYPWALSSGTVSYSGSPDFSGSFGFGAYQDQAAYFKNVHVYDTANGSTLYSNTLTGSAEDILAEYGTQANSEAACLDGPKRDRLIWLGDFYHTARIIAASTSKTEQARGTLQLLLDSQIANGQMNISPNLGYNLSSVADALAPAGSFGLQDYQLLGLMAFNDHVRLTNDLDWARSTWPRWQRVLNWLLPQINSTTGLLTFDGGFAFTGPADGGSAIGCEAVQTLNGAADVADALNDTASATQYRGAAMSLANAINERLWNEEAGAYGLSLTDLDGISVAATAFCITSGVANATRASRSLAAVSRLKLGPGYKDTSVVSSNDSSVNISPNTNGFLLEALFVGNETQAARELMESLWGAMLPGDTTAAQNRSAVGASWEYVNAATRQPGLGLFTSLSHPWGGAATYVLTEWAAGLRAAAGVDGFGYRNWMVSPATGVEMGLKRASAKVVTAFGGELSVEWRVREGDIGVSIWAPVGTQGRFVYGNKSIALHGRSEYQFTVDASLDNGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHS2</accession>
    <name>A0AAD8XHS2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_187625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367792.1">
        <property type="nucleotide sequence ID" value="XM_060501569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHS2"/>
    <dbReference type="GeneID" id="85385468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="611" mass="68899" checksum="24E26783A3A0139D" modified="2024-05-29" version="1">MRDTIGTIEISPTIWAQSTGSQHNQPQPGTQNASSQPIPIRLTNPVKYSSEYSTSPDSATPFIQSMTSSYEAQPPWPPREHTPPSGSEDGPPKGTQLPSTAGQPLKEQDQPLDEQPQPQLQPEPQPQLSDQLPTDTEPAPPSQSVPFIDDDNLSKDFEQYEKGSKLVLTYQAPRRPYGRSEYPNPPGIDSDDKVLSEAERRLSRTGLVYHDRQISNPIADQYKATVHLTVMKIISGGPVAGTQVILCKVDEASYDDGMSKKQKGTLLRGVSLLRTKSTRVKKRFARSSIANLFGQENAGGFSLSQGTGSKKEPDVAGNAPVVVPFDGERLAVGQLAVLKVYDAMFYPFQYGMYQGPWKVTSRADQEHSREAGAYKHLWTHKKTGYPHLTPQYYGSWAIELTTTNSGVKDKQRFARAIIMEYIEGTSIEELCFRTAKEYLLVPRNMMKPKMADGTTWYFDRKVRLEVFEELLIGYVNMLHHGVNMRLDPQNILLTGKRGDEVLKTTHLRVVAIDYVDAMIDDERKEPLRIYQIWDKPPHPWGETSLPKMQYFHGWFPHHWTPAHFDSWLIRTFGQLDNPKYMDPNISKDPNLSKTQASKQSELDKDSQPSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHT4</accession>
    <name>A0AAD8XHT4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sfi1 spindle body protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_579937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363880.1">
        <property type="nucleotide sequence ID" value="XM_060505297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHT4"/>
    <dbReference type="GeneID" id="85389196"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013665">
        <property type="entry name" value="Sfi1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08457">
        <property type="entry name" value="Sfi1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sfi1 spindle body" evidence="2">
        <location>
            <begin position="399"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Sfi1 spindle body" evidence="2">
        <location>
            <begin position="660"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="900"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1039" mass="116000" checksum="CDB93F8FA7C3EAA3" modified="2024-05-29" version="1">MPSLPHRPVLAPRDGISSFVSVQSSDSYYSDHEIAILHRVVTAAQENLELLPEGERLATNALFQAYDAVLPLFGIDPEEENHISRLVFRVGGERGEGSLQEKLDAVLSRMGIGLEFGSEGSRALSNNGDDENEDEDGAGAGYEDAAPPQSALTDTDRDSDTSGDESSKDVELAPREPYAPLPPSQAQASHHLYDAESPPRLTRVGLVSNHLDLKPVNHKKPPSQSYTPSTAGNTEQSRQSRQSVSGTSVQRGASDTTVQPIEASNIYPANETEAAALPIRTKPVRTVNWVLPPDITSISTGTSVGATAPESVRNGTLGSEIAEDHVVHDVETRNSRGYELGTQKPSVHALVVHESTAQEITTHQAAKQMQPVEEPSDGGIEGDKAEPVIDDEINADPDDEARYALLEWKSTKVKGYLLLLRGLSHWKQHALDKLERMAVARRHILRMRHFDPWELVTAETRIRGRRVFTSRLMASWLRRAGEDLDTEYASLAHAQRNTAQNALRHWSTSCPTPMEPRYPPRVVSIYLQQWHSACSVSQRLESHMENLYEEYGRFRILKTWSHQAASHLRDVAAFRKYHVVQGALHQWHLDSRIEVFKSKLEIKLVRSCLSRWQNGCRAPPTLGQTNAFSRGIVVDSASGRALPGPRRGVSSHMAISYRLLKTKVLGNWQRQASMVAKSSTRSRRFASHQGAHKALEMWHIDVGEKRNLQNWVQRGCFYISATHALKTWRSRSAWRSGTRKSYARCRQHVKATFTKGYLNLWKIANRAHGNLGWKAGQHHIVAEHDRLIDMLKLWRDESSRDWGTGKLLTAAWVDEWNGMSQDLAVKEDRVKQTWSVNLKSRWWSQWQSSLLQLKSREYVALDVRERNSKKAVRRLLLHWKGDRNLSTSYQSTTLRASLGSSRRGAGFMTSRTSLPLSRAVHERPSGPSLRGSRIQEVEPTADDDDHDGTGSGPDTDGVVADTPTRWTGMASSVRLPSMTPFAPLPTPFERELRERYNRSVPTAATGQMSSLSFAQAQRLSVAGTRRAATEKTADVGRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHT5</accession>
    <name>A0AAD8XHT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_239485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366926.1">
        <property type="nucleotide sequence ID" value="XM_060501865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHT5"/>
    <dbReference type="GeneID" id="85385764"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="206" mass="23261" checksum="65A7B4B334F0CD4F" modified="2024-05-29" version="1">MRLSNPRVSRNCHPLKQPPSRSFTVFCCRWLDNLFIIHDGSARPTEHPPMQTQSEGKGDRDRESDSCTSSSRACLLHPDNTPWLRRAALRCGAMLCDVFAMHQGFRQNVVDASSNKTATIQETRVQLIDSGICWCIRDTRGRNNAFRPVFVRDVSRLLNSVPIFAISAGIFQDLACSPLHVLQAKVQVQPKDDVISQCWLMRPPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHY0</accession>
    <name>A0AAD8XHY0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_364184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364030.1">
        <property type="nucleotide sequence ID" value="XM_060502600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHY0"/>
    <dbReference type="GeneID" id="85386499"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042285136" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11622" checksum="BAE07EE98EC9BB75" modified="2024-05-29" version="1">MGMTNSTAASCASSCRLDFVLILLIQTLSATSHAVAPIGNVCTELSPWSGFAPSGLWNPTLQQRVARLARYLARLGLACLCVMQEVAPLLQVQTTGTSSASRNRAIRSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI11</accession>
    <name>A0AAD8XI11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368829.1">
        <property type="nucleotide sequence ID" value="XM_060510180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI11"/>
    <dbReference type="GeneID" id="85394079"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="16669" checksum="B9C8F680AEDFEC73" modified="2024-05-29" version="1">MDKGCNIKTKQRGGEDDDDDDTRGAPAFFPSTPEQVIHGTHGDQSIVRKSRQQTGLGGFGSRGSHSQLELVPRSCLRNEKTESTFTPSLNPPRCCWMTSREILVQQRLLASTRRVETKRDNDHRSGNAVGSNVYSNGNFGVCECVCPVTVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIL4</accession>
    <name>A0AAD8XIL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_611291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367916.1">
        <property type="nucleotide sequence ID" value="XM_060507652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIL4"/>
    <dbReference type="GeneID" id="85391551"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF12">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="232"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="583" mass="66854" checksum="880FC05FD0BCB3FB" modified="2024-05-29" version="1">MWLINTSSHNLEEFIGRDIPPYAILSHTWGEDEVTFQDMKDPRFLVREQTIRKAGFVKIAKTCGLAHQQELQYAWVDTCCIDKSSSAELTEAINSMFKWYQRAAICYAWLSDLDPSADIDSDFDGSGDLGQCRWFTRGWTLQELIAPKEIEFYDRDWNLVGCKSGLVDQLHAITAIAKDVLVNRYGALLHTCVAEKMSWAAGRETTRVEDAAYCLMGIFGTNMPLFYGEEERAFQRLQNEILRESDDVTIFAWERVSYRPPPDQCFSDGGRILGGVLAESADDFAVHRHQRKIYPPPIRRPALEVTKNCIKIYTELVWEEAPEISGRRYYIHCGSRGEKHVAIRLVKIEGGSFVRGDLNQCVSTCIFHIDAQRRREFSLLVNTSSYPIRLLSHGGWDLVKMKFRCPKNMKVAEAWPWSKWHDEESEFVAYPTRLCGSILFHVYHTVPSTDHMVTPREGHRTDIVFIFNPHEIHSDIQEVKGTLLERYGEYQAKVDHIHSFLDSEEPDNLGFHDLLAQIGLPTSNKVVFDLGTSKRSAVLSFTSKKLTVPMTRSTSAAWEITFGMNESKRFIGPVKHKKWQADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIP8</accession>
    <name>A0AAD8XIP8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366503.1">
        <property type="nucleotide sequence ID" value="XM_060513969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIP8"/>
    <dbReference type="GeneID" id="85397867"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042025300" evidence="1">
        <location>
            <begin position="20"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="54565" checksum="84170A7D933A3303" modified="2024-05-29" version="1">MRFSFVAVWLSSATALAAAAVDWKTVKCQGTVIDAKALPDKRWAAAGATEALNEVLKAWKEYDSGPNEVKFEFSQFASWYLGGPEMWRCTQLLDVPCSTSLTCEDTKYPAGHLILNSFSKMHQFHRRYFEALDQAQMDIQSEMGLFAEKFSVPLAESDSSARMQRIMLNVIYGVVGIAQAYTNNIFVYSTLFQSFLTQTMRSQITTTSSYTIFTSWAIGKDFLLPGASPKPAYGTLSAMMGDVFDSWKAAEVEYLKRIFTPRDDATIKFLTAALDNGLMSATPDDIDFREMSKVIKKLFYPNLMLAAWETVPSARRPFVLQTGLPCKMGKTERDDSLWPFLPADSHERAAACYNGALFYLLDIRNEGVELSIGHPSIRPSENNPFSALFGTDTMDGKQWGGVTKEDIVAAVYGGWVEGGRMNNNFNMNYTNIQPSEGSSLWFGNGIRVPGYVKMPLCNNIYTIVGNVEFGKPETNPSWPCASLPVIKPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIT7</accession>
    <name>A0AAD8XIT7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_749303</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Positive regulator of amino acid starvation-induced autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
            <location evidence="4">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SCOC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368351.1">
        <property type="nucleotide sequence ID" value="XM_060513746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIT7"/>
    <dbReference type="GeneID" id="85397644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019357">
        <property type="entry name" value="SCOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614:SF0">
        <property type="entry name" value="GEO08385P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21614">
        <property type="entry name" value="SHORT COILED COIL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10224">
        <property type="entry name" value="DUF2205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17999" checksum="DE90024CD0F63254" modified="2024-05-29" version="1">MDNEHQAQFSEQSHLPPHIERSQSSSSSSSVDHEHDEHHIHQPTPIRPRLPSRKSSGPLVVPRDSSAVGPVDAEFGPDDVRAMSPRRTSEDIEALGREAREELKRHAKALQDSLLTIFNRIEAVREEHDKLDNNNKFLQKYIGDLMTTSKITAAPTKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJL5</accession>
    <name>A0AAD8XJL5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_729342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366925.1">
        <property type="nucleotide sequence ID" value="XM_060512818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJL5"/>
    <dbReference type="GeneID" id="85396716"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="552"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="719" mass="79244" checksum="D052D621E7237238" modified="2024-05-29" version="1">MSDNQGIKERPSKRSLTPNKALYASFNEAHRHIAPPTPRIPIEFDGQLGDGGQLTEQQVEDILSASNESSGQSQDSKVQKEPKRLELFAEPDASGHQSKVDKQASPPIVESQTQTTEHGPQRSSSPYLSDDENAFIDCSILSIHEFKEQHDRQDSIDDPFDSQHAATEYPDASSFYPEDGDDYSLASIDDGPMNKIKVEPRSSPVLASSPILSPPVAASPSWHTEEGDQSSHIDDIVKKETPSGYFNTTHLSGLNGTQYPIFIDHEALQPGNESNHLPIFIDRGVLPPPSIPTDQPVPTIEQTSQSESDYDGDASGYSEDEVTNQDKGKAPVKLLNPFHAFSNASSHASDHNVEQSEPGKEKVFLRPHAEKEVSRALHHVTGLSQPSSGLISRVRHSHLQNSRLSPYHSSSDQQKNDFYHAPAIQPDWQITQSGIKVPVPVPASLTGDEFGIQATEPYDAIDHTRMATVASEDAEERTGLEGDEDWRTVTDDREFPIGFVGRVMTGSSIANVSDALLVQHQQQHPVAQHTASHKGREPSTTRARAWWEKSTPLPSIPSRSASPSYPSPPARALQNRQRRQDGWEEIELDPMPAPYPDFSWDRVRNDRAQCNKETAQPSRNEYANLPFPLVPREDAAKLQAFRRASGLEDHTLSGHIISPGLPSPSNSGSHVYPRPALRKNSARSFFSRTENPGVDRRTIFIGKSPVSAFLCSTDLSSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJN6</accession>
    <name>A0AAD8XJN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_738673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368648.1">
        <property type="nucleotide sequence ID" value="XM_060513028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJN6"/>
    <dbReference type="GeneID" id="85396926"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18657">
        <property type="entry name" value="CSD_Swi6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="105"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="300" mass="33076" checksum="EE25D758FEC33859" modified="2024-05-29" version="1">MARRKANKGKKPMKLTAPIAISDDEMSDAGGEIAIPLKEKRAKSRSAEYRDDVSEAKSEEDIPIISGDLNGNATKPAKAAKAASVVADEEDEEGDEDDDLEADEYVVEKILDHLASEDGTVNFRVKWEGYSKKSDQTWEPEDSLKEGASEILEEYLQKLGGREALFEEKTKAKATKKRGRPSASSSTPPASSKRGKRNGHPAESTPPASAKEAKAKAWTLPSGSWEDDVESIDACEDEESGSIIIYLNWRNGQKTKHPKEVVYKRCPQKMLQFYEKHIRIIKAGPDADLPDLDTAPEAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJW2</accession>
    <name>A0AAD8XJW2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glycine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_610781</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 ATP + H(+) = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34935"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368020.1">
        <property type="nucleotide sequence ID" value="XM_060507609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJW2"/>
    <dbReference type="GeneID" id="85391508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00858">
        <property type="entry name" value="GlyRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.230:FF:000002">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000010">
        <property type="entry name" value="Glycyl-tRNA synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="16">
        <location>
            <begin position="286"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1727965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="749" mass="84142" checksum="F81D1C08DFC26A70" modified="2024-05-29" version="1">MKPFRFVAHQSPSIRSTASFCAVRPAAFFHSHQRYPSPSSHYSNPYYSSHQRTLTTSRHLSRAQVLVPSKKNKPPSAAAGSSSKMTTTATTLKGQPLDRQTLDAMLRRRLFFTPAFEIYGGVAGLFDYGPPGCALQANIVETWRKHFILEEDMLEIDTTVLTPHEVLKTSGHVDKFADWMCKDPKNGDILRADHFVEDVLEARLKGDKEARGQKVEEEDDPKKKKKRKTKAEAVKLEDAVVQEYEEILAKIDNYNGEELGELIKKYDLRNPNTGLQPSPPVAFNLMFQTAIGPSSNLPGYLRPETAQGQFLNFAKLLDFNMQQMPFASASIGKSYRNEISPRAGLLRVREFLMAEIEHFVDPEGGKKHIRFPEVNTVELTLLDRHTQLAGKTEVKKMTIGNAVSNKVVDNETLGYFLARIHLFLQKIGVDMTKVRFRQHMENEMAHYAADCWDAELLTSSGWIECVGCADRSAYDLSVHAKKTGAPLVVRERLDEPLVFEEWQVEIDKKKFGPQFKKDGKTVEAALEETTQEQREKLAKQLTDNGELELEVAGVGSGTVKVSKDLVKIEFRKRIENTREFTPNVIEPSFGIGRILYSLIEHVYWNRATEDGAGDEARGVLSFPPTVAPTKVLIVPLSANKQFQPFVSKISQKLRKYGISARVDSSSATIGKRYSRNDELGTPLGITIDFQTVQDSTITLRDRDSTKQVRADEDTIIAAIQSLVTGAKEWKDVAAELPTFESQEVDVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL93</accession>
    <name>A0AAD8XL93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP synthase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_568499</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369487.1">
        <property type="nucleotide sequence ID" value="XM_060504076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL93"/>
    <dbReference type="GeneID" id="85387975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="48"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="131"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="20443" checksum="E63AC314D435F5EF" modified="2024-05-29" version="1">MSLTYGLGGIGSTLLVVGAYMLFTGSGEAFNVGEFLESISPYAWADTGIALCIGLSVVGAAWGIFITGSSILGAGVKAPRVRTKNLISIIFCEVVAIYGVIMAIVFSAQLENVQGEVLHDGNSYYTGFALFWAGITVGMCNLICGVAVGINGSGAALADAADPTLFVKILVVEIFSSVLGLFGLIVGLLVSGKANAFGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLK7</accession>
    <name>A0AAD8XLK7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribokinase</fullName>
            <shortName evidence="9">RK</shortName>
            <ecNumber evidence="9">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_568369</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369594.1">
        <property type="nucleotide sequence ID" value="XM_060504061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLK7"/>
    <dbReference type="GeneID" id="85387960"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584:SF166">
        <property type="entry name" value="RIBOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10584">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="10">
        <location>
            <begin position="8"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="44"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="243"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
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        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
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        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="34218" checksum="FE322D3E17BBB8B7" modified="2024-05-29" version="1">MAATKTPQITVLGSLNIDLTSYVPHHPLPGETLTSNSVVISPGGKGANQAVACAKLSRSREAPNDAASETASVSMIGAVGSDSYGDLLLKNLGEHGVRTDRIAVGSDLKTGMAIIVVDEPTGQNRIILAPEANHAVTSEKFGTLPETLNPKPDLLVMQLEVPLETVLAALRSAKAASVPVVLNPAPAQRLPDEAYDGLAHLVVNETEAAILSGCDESELDTPEGLNRVGEWFMAKKVSNVIITLGGRGVYYANKEGAAELIAAQKVKVVDTTAAGDTFVGSYCVAAVTAQAKGVAFDISSAIKSANNAAAKTVERKGAQTSIPWRDELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLS3</accession>
    <name>A0AAD8XLS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_15764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369775.1">
        <property type="nucleotide sequence ID" value="XM_060501372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLS3"/>
    <dbReference type="GeneID" id="85385271"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="41253" checksum="7DB43A0A760BC82D" modified="2024-05-29" version="1">MQLRQTASTGRLRARPSRTRSRPPKMPTASISASSSTQKPRHFSNNSVSSIQSYGTDMTTSTIRKRHARDIFAEFGIPRPSGWLSDDEEEDFSRHRDGTNSIPRHVLNTCHSCGAEVTSRTFCSSCGHAVCPQCASEIPDDGSIDFEHTGSSHRNAVTSQHHTSRVTEEHIRSSSSLETTETSKKNQRAPATSVNLNENPFILADRMTKITTVEPQITDMTVGAGQASRLSDCVPRQTDLNTAETHGDYGNPRCNATHAGHHPGRHSIACIDNQQSSANMDESEPLRPHLPLEDPVQNKIDQMYHHAEDLRRAQHIMEHLATGSAGISASKQQSQHTTPPQQKTQPGTEDHDTNREKLISFDAAMAENSERARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLT6</accession>
    <name>A0AAD8XLT6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_567855</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369733.1">
        <property type="nucleotide sequence ID" value="XM_060503998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLT6"/>
    <dbReference type="GeneID" id="85387897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="363"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="56"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="627"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="667"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="808" mass="87674" checksum="1CE75B05BF6725BB" modified="2024-05-29" version="1">MAAEVRRSNGTRLDASLGITERIAPSMVAWTGDMRKRYTDFQVYEISKDGTVLHLTETRLPPPPKETTPPPPAPPAPAAPVVEEKKEEEPKPEEPSQDGEAAEKPAAVIPEVPAEDIALLASLTNDDFANQLVTIYKTISADKTAKTEPVTSPVMDDKDKRSQIHQNVRRIFNSTIDTTTDPTGAIVARVPPPRGKGKGMRGGRDNNNNNNNNNNNNRENNKQKKKQPKAVAPGEGEYLHFTLYKENRDTMDALHQISKALRVKPQAIGTAGTKDRRAATTQRCSVRGQRADALLRARLFGVTVGDYRYAHSPIHLGAHRGNEFVIALKDCLVAGNHNLPPADRSSQIRASVEAAMASMHNPGWINYFGHQRFGTHAIGTHEVGRLLLQGDFEAAVNAILYYDEAIAQRALAGEVPDQGHARDELNRHRACKVFRDGGSAEEALSHLPRRFSAEASLIRHLGRTTAPSRRDFNGALTSITRGLRNMYLHAYQSYVWNHAASHRWRLYGKNVVEGDLVLDTSSADADADNEGGDDDADASSAPARALTAEEAASGTYTIHDIVLPSPGHAVAYPTNAIGEFYTTFMRDNGGLDPHDMLRRHREFSLPGAYRKVVVRFLSEPSFEVRTYEDDEEQMHPTDMDRIRAAAGRGGNGKKRGRQEDENAEDQDAVKKVKTETATGTEEKADEPMQDAPTQASEPKQEQEPEQQAETTASDSNGSPKPSPEKTKTAVVVTFQLPKSAYATVALRELMGVDEAEVAAAPTGASAPAAVPAAAAAAAAAAAVITDTTAAATEAVEVPEISETTTTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLZ9</accession>
    <name>A0AAD8XLZ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">EB1-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_716217</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369804.1">
        <property type="nucleotide sequence ID" value="XM_060511829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLZ9"/>
    <dbReference type="GeneID" id="85395727"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035372">
        <property type="term" value="P:protein localization to microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1430:FF:000005">
        <property type="entry name" value="Eb1, isoform E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="11">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="EB1 C-terminal" evidence="12">
        <location>
            <begin position="154"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="27135" checksum="518A3FC451DF14C3" modified="2024-05-29" version="1">MGESRQELIQWLNQLLSLNITKVEQCGTGAALCQVFDSIFMDIPMSRVKFNVNSEYAYIQNFKVLQNCFHKHQVDKPIPVEALVKCKMQDNLEFLQWTKKFWDLNFPDHEYDAVSRRKGAPVPSGGGPAPRAASGTGAAAARRGGTTPLGGARVPKAAGPGTAALQQENATLKETVVGLERERDFYFSKLRDIELLVQQAVEEDPELEKQEDGLVKQIQTILYSTEEGFEIPAEGEAVDDQETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMF1</accession>
    <name>A0AAD8XMF1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_715848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370064.1">
        <property type="nucleotide sequence ID" value="XM_060511789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMF1"/>
    <dbReference type="GeneID" id="85395687"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11399">
        <property type="entry name" value="bHLHzip_scHMS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="225"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="38005" checksum="A455FFE9BF78BD8E" modified="2024-05-29" version="1">MAQQQSFDYYQVPPMPQSMSPPELSPLSFYDTQADFSADSAPSRGSPVSPVFPTSSFQLPTGGDWPAYFEKPALSPDLDVFYGESFGSPMSFLSPQNLTLSPSANPSDLMSDAVAFGREGINDTQPLFQTLDAPARPQPQPQTQQPAKSPRLARTTSAPSSRPQQQPQRQQQQQQQQQQQQPQPQTQQRTSPRTNDLKRKSSASSASSRSASPEPPARRTKHSEPSKNPHNMIEKRYRVNINEKIIALRDAVPSLRCVVQHTENPQAAAAESDEAIDVVEELGGLMPARKLNKATILSKATEYIAHLEKKNSQLWKENEALEKRLAEAQQWQRAQAEGPFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMF9</accession>
    <name>A0AAD8XMF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Farnesyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_453128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370044.1">
        <property type="nucleotide sequence ID" value="XM_060503166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMF9"/>
    <dbReference type="GeneID" id="85387065"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000006">
        <property type="entry name" value="Farnesyl pyrophosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="347" mass="40175" checksum="ABFC83755E289BA1" modified="2024-05-29" version="1">MAKKTTLAEFESVFPKLEEVLLEHAQKYKLPKEELAWYKKSLEINTLGGKCNRGMSVPDSVSLLLDKPLSEEEYFQAATLGWMTELLQAFFLVSDDIMDSSITRRGKPCWYRHEGVGMVAINDAFMLEAAIYTLLKKFFREHASYVDLLELFHEVTFQTELGQLCDLLTAPEEKVNLDNFSMEKYRFIVVYKTAYYSFYLPVALALHCLNIATPKNLKQAEDILIPLGEYFQIQDDYLDNFGLPEHIGKIGTDIMDNKCSWLVNQALAIATPEQRKILEDNYGQKDKAKEAIIKELFDDMELKRRFEEFEEKRAGEIKDMINNIDESEGLKKGIFEIFLAKIYKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMZ5</accession>
    <name>A0AAD8XMZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_788211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370391.1">
        <property type="nucleotide sequence ID" value="XM_060515675.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399573"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000030">
        <property type="entry name" value="Histone acetylase complex subunit Paf400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="6">
        <location>
            <begin position="2673"/>
            <end position="3230"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="3496"/>
            <end position="3822"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="7">
        <location>
            <begin position="3819"/>
            <end position="3851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2027"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3239"/>
            <end position="3323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2049"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3247"/>
            <end position="3265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3298"/>
            <end position="3320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="3851" mass="439279" checksum="0623C2FFCC6BFDB9" modified="2024-05-29" version="1">MSGTTIDDVVKRLSSPDTDSRVRLEAATTLRDSLDHYTNGTIYPPFLKRMVPIFLTILRGPCIFQSNSPEQKLRTCILEVLNRLPATPSPTEPFEPYAEEVVDLLMQLVRTDNEENATLCVKIISDVMRHQHKVLQGKVQAFLNLIQELFEQMEKVVREQLDNTSLSTASNSGAPSTPGSSQTNFQSPRPGSPVASVTDLGPDPQQQNRLLLKGMQSFKVLSECPIIVVSVFQVYRNTVASNVKAFVPLIKGFLCLQASAQKQAHADAKARGQIFTGVSPLIKNRAAFGEFITAQVKTMSFLAYLLRQYSQQLTDFLPTLPEIVVRLLQDCPREKSSARKELLVAIRHIINFNFRKIFLPKIDELLDEKTLIGDGLTVYETMRPLAYSMLADLIHHVRDSLTPEQIRKTVEVYTKNLQDNFPGTSFQTMSAKLLLNMAECIAKMPNKVDARHYLIMILNAIGDKFVAMNRQYPNAVKLSKLYAQQAADGTQDSYLADKDHPPDWDETDIFTAMPIKTSNPRDRGADPVVDNKFLFKNLMNGLKNTFYQLRTCNVNNVIDVQNAPQHWQDVAYGFTAEEVNVIVKLFREGAYVFRYYEIEKPATESQYMSPVEYMANFYMVSSSKEEKELLETFATVFHCIDPATFHEVFQQEIPHLYDMIFEHTGLLHIPQFFLASEATSPSFCGMLLRFLMERIDQVGSADVKKSSILLRLFKLAFMAVTLFANQNEQVLLPHVVDIVTKSIELSTKAEEPMNYFLLLRSLFRSIGGGKFEHLYKQILPLLEMLLDVLNNLLMAARKPAERDLYVELCLTVPARLSNLLPHLSFLMRPLVVALRANTDLVGQGLRTLELCVDNLTADYLDPIMAPVIDELMTALFDHLKPHPYSHFHAHTTMRILGKLGGRNRKFMTDAQPLNYKDYADDPTSFDLRLIGSKKDRAFPAETGVDFAIRKLMEQPKAGKGNQARQYDGYYKKQSFHFIKSQLKMRIGFENLPDDMPRLLRLQAQDLAARRIDFDFSVFTTHDRERSIPKKDEQDDLLKRLLKAVMFAESLPDFKEEAQTFLMNLCKHFTIIEVGRALVDVKRTYSPFDPNAGEGQLFIDTRVLSDAIVESLASDHPEVRESAQRAIREVYDSATTILGNEQSVARLPLFNNLSTTFCHGCYEEEWFTKTGGSLGINFLLNELDLGDQWVAGKQIEFIRSLMYVIKDMPQDLPEKTRRSAQVTLETLLHKITKNIKKEDAMPQQNPGQPPQQRSRLAQICMQFNTELAHMNRHVRETAKRSLELIAKAANCAVWELIEPYKERFLQPIYSKPLRALPFPIQIGYIDAMTYHMTLRKEWVTFDDNLTRLLMESLALADASDESLANKPGEFRTHEYIVNLRVACINILSTATSFEEFAPLKQGSHPTRSKIVSVFFKCLYSDSKATIDAANSALKNTLEAHQKLPKDLLQGGLRPVLASLQDPKKLSTHGLDNLGRLLKLLTTYFKVEIGARLLDHVKVLAEPSTLQQLSFTFFEQNGPMKVIAAVFNIFHLLPPQAEGFKQRLIDLALELEEKLRRTHESPFRAPLYKFINRYPNEVWNFILPKLEDLKYGRFISQVIRNPESGPLRDTVSSNVQALIDFCNNAISQNKDSKLVTVVNAVHILYSLTLSPGTDTWLEKKEHLTWLKQVGKELEKQMRAHTLAPNLRLPACQASDQLMSIFIKSLERNPKDLESLFSLVDSVTTDDLRASQPLIAYIYKNIVSSDSPEFWKSTVLRCLDAYPQKNITQKMKCFLLHYIVNPIVAMDVQRNWSLPPQTKGRFMDKTIIDAVNAKIWKLHQDASQHDNDDLLQPGIDHTKFEVLQLSAMLVKYHSTIFQEARKDIIKSCWTLIRLDDVINKHAAYVVIAYFIALYETPVKIVTQVYLSLLRANQNEGRALVTQALELIAPVLPKRLGTQAHDRNAGWALAPRKILADEGQNVQQMTSIFHFLVRHPDLFYESRDKYAMLIISSLRKVAAPPNPSNESKKLALNMMWLIWLWEQRRVEGKGDAVSRSISESPTSKKRKLDSADQPMSSPPTVRQSLGGNDYQIAHVARQKMIKYLVEFIAQLNERYQLPSTKARDNASTTGPAMPPTSTELCKKAMSLFYNLVQPQYWGDLDIDLYPNVTDVVLASDKTQNFLAADPSDEKFDEKFITNIINTLQVVRIILNSKPDEWIAKNMPSVQKVLDKVLKSENPELQDCLHLADKKYDDDRDLKSIIQRVLDAVPEDVPMEDADAEGETESQNSEIINSLSSIAGEAMAAGHYGSGVNILWSLGNRKPSVIDQHIPVLMKALQSKLAREHVQHYTAVANHQAGQPRTQDANTPTGEMSTYDLEVSTALMTKAIQVVALRMEVLGDNRRPFLSVLATLVEKSMHIPLCEEILNMVEGWVFRSEGTWPTLKEKTAVLHKMLSFEHRQDSTMLTKFLELVIRIYEDPKITRTELTVRMEHAFLIGTRAQDVDMRNRFMAIFDKSLSKTASARLAYVLTSQNWDTLADSYWLAQASHLLLGAVELNSPIQLHQEDFKTMPLTQLFSIHAKDNREPTSMSDDKLDNLVTAHRRFMSELGEVKVRDLIEPLVQLQHVDNTLAHQLWIALFPIYWSATMKEERTDLERGMVALLTKDYHSRQIDKRPNVVQSLLEGAAKAWPDCKIPPHVLKYEAKTYDAWYTALVQLENAAIKPEIESATVRESNLDALVELYASLQEDDLFYGTWRRRCQFVETNAALSYEQNGMWDKAQKMYEAAQIKARTGVIPFSQGEYVLWEDHWVLCAQKLQQWEILQDFAKHENFQDLLLECAWRNNTEMWQTQEHREALDNLIKGVMDAPTPRRAFFQAFMSLLKFYNKQETPQDFAKSCDEAIQLSIRKWHQLPKQLTKAHIPLLQNFQQLVELHDASVICNSLASTNQSNLDVKSGELKLLLGAWRDRLPNVWDDITAWQDLVTWRQHIFGLINQTYLQLLPQGGGQNASGASFAYRGYHETAWIINRFAHVARKHSLPEVCITQLSRIYTLPNIEIQEAFLKLREQAKCHYENPDELTSGLDVINNTNLNYFNPPQKAEFYTLKGMFLEKLKQKEEADSAYGTALYFDITAAKAWAEWGYFNERKYKEDPTDINSARQALTSYLQAAGSYKNAKSRKLIARILWLLSLDDANGSIAAGFDDFKGETPVWYWITYIPQLLTGLGHKEAPRVHQVLSKIARSYPQALYFQLRTNREDMLVIKKNQEAKEKARQRAQSTVSNGKPSASPQQPKQDGVPKPDASGSRPGTASGGEANASVKTEGNDANGTPAAQANGAAAGGDQSAAGQKKPPWELTEEIMSALKTAFPLLALSMETMVDQIQKHFKCPPDEDAYRLIVALLNDALAYVSRMPSSFAKDVKLPSATETNITRFAETILPAHIKKSFEADFVTVKPTMYEYIHKLRRWRNKFEEKLDRRTTRVSLEAFSPHLSEFRYQRFDDVEIPGQYLQHKDKNQDFIRIERFLPNVDLVRSISASYRRLQMRGHDGSIHSWAVQHPAARHCRREERILQLFRQLNQTLGRRKESRRRDLQFTLPLMVPLAPHIRIVQEDTSYITLQSVYEDHCRRHGMSKDDPVLFTMEKLRGVLDTKNSKHAEQSATARLEVFHAIQEKWVPQNLALDYFQKAFPDFTEFWLFRRQFSYQLASLTFMTYILYMHNRYPQKINIARGSGNIWGSELMAYMSAAKPFFHNPEPVPFRLTPNLQTLMGPLATEGIFSCALMAIARCLTEPEYELEHALTLFVRDEMIFWFTSSHRTVQMTENQLRESVQVNSDSVVKRAVSLAQSPVGNLPANQTVIDLVAKAVNPMNLAQCDALWMPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNB9</accession>
    <name>A0AAD8XNB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370531.1">
        <property type="nucleotide sequence ID" value="XM_060513407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNB9"/>
    <dbReference type="GeneID" id="85397305"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="21261" checksum="C591062800B18613" modified="2024-05-29" version="1">MSIHRELNAASLSDAWRTINIDALQEDSACNFDTNTLRPPQPEIGEDEVRQLAGQVRQLLRGGDAEGALRGCLEFPVYNGPDGAKDAHLQTITEVLQSIKASEMTPLLKSIYGGAGGPELLDVLMKYIYKGMAGSAASGGLRSPPPQAAPSGFSQMGGRPGATNENVGSAMSVLLSWHEKVVDVAGLGTIGRVMTDWRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNE2</accession>
    <name>A0AAD8XNE2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Necrosis inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_715565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370539.1">
        <property type="nucleotide sequence ID" value="XM_060511757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNE2"/>
    <dbReference type="GeneID" id="85395655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041997306" evidence="3">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="238" mass="24633" checksum="512F2ACF0986F476" modified="2024-05-29" version="1">MAPSLLRLGAWLAAAAGSVTAAPLERRAVIAHDAVVGFPETVPSGTVGSLYLKYKPYLKVVNGCVPFPAVNAAGDTGGGLATSGSSNGGCSSSTGQVYARGASYNGAYAIMYSYYMPKDSPSSGLGHRHDWENAVVWLSAASTSATVLGVAVSAHGEYDTKTSGIDYTGTSPRIGYQSVWPVNHQMIFTSDVGGQQPLIAWESLTDAARTALTNTDFGSANVPMKDANFNTNLGKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNU2</accession>
    <name>A0AAD8XNU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_600375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370777.1">
        <property type="nucleotide sequence ID" value="XM_060507029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNU2"/>
    <dbReference type="GeneID" id="85390928"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18026">
        <property type="entry name" value="DEXHc_POLQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.20:FF:000005">
        <property type="entry name" value="DNA-directed DNA polymerase theta, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057220">
        <property type="entry name" value="DUF7898"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046931">
        <property type="entry name" value="HTH_61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048960">
        <property type="entry name" value="POLQ-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25453">
        <property type="entry name" value="DUF7898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20470">
        <property type="entry name" value="HTH_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21099">
        <property type="entry name" value="POLQ_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="144"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="393"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="879" mass="97160" checksum="D0AEB9ED2DD09CDE" modified="2024-05-29" version="1">MATNNGIWHKTSVEVAEEQGRAYHTVTTTIAGQKRPRAESAHPTAPKPTILPRHTSVVQRASSLPPGPPKLTASPIISLSPAATQGPSEYTQRREFQSTPSSSSDPLLALAHPYYGLPRSLVRNFYSLGIKIMYPWQKACLRGPGLLAGEGNLVYGAPTGGGKSLVADVLMLKRVLEEKNAKALLVLPYVALVQEKVRWLRNIVQGVMKPKDEIDDEKRIWRRRADEDTIRVIGFFGGSKIKPTWSDFDIGVCTIEKANALVNTAIDDCTIKHLKSVVLDELHMIDDDHRGYLMELMGTKLLSLPQPVQIIGMSATMSNISLLATWLGAHSYETRYRPVPIEEHLVYEGNVYPATTTSELLKTAKNLNTATQKTGSRATRRIEPSGHKEFQDPVLNAVVSLASETAKAGYGALVFASSRYGCEADARWIAKVMPTLDELDPGLVEKRGELMAELRSLGTGIDPVLEETVPMGVAFHHAGLTTEERDIIANAYDAGTLKVCVATCSLAAGINLPARRVILHNARMGRDFVGPSMLRQMRGRAGRKGKDEVGETYLCCRKDDLEQVVDLMHAEMPQITSGLMTDRKRIQRALLEVIAIRLATSRDALNEYITKTLLSHSGPLDSLQDCVEVSLGNLTNMGFVSVDDCENYQPTKLGRAIVASALDPDDGVFIHKELERALQAFVMDGEMHILYTFTPVQDSGISINWQVFRNEMDNMDESGHRVLGFLGLKRAVINRLAQGSALKETTAEEKEILRVHRRFYMAFQLRDLCNEMPIHVVARKYDVPRGAVQTLSQSCNGFAAGMIKFCEYMDWGVMSAALDHFSDRLRAGAKADLLALAKITFVKSRTARVFWENGFRSIAAIANADPNELLPILMQVSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP83</accession>
    <name>A0AAD8XP83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_747225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370972.1">
        <property type="nucleotide sequence ID" value="XM_060513401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP83"/>
    <dbReference type="GeneID" id="85397299"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="489"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="522"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="555"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="621"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="687" mass="74909" checksum="64561BEF6CC41601" modified="2024-05-29" version="1">MDPITALTSAVELFGVARQIQSLVEKYKNAPKAVHEIIVECNLTKDVCLNLKKQVSQTDVLKNPVKNSTEDGLRNLLDTCMDKLTKTLKDLERELSKVQSKSDSRMGKWDKAKFLWKEEIFSDAAQSIQDQKARLGIVIQLLQVRTGQEVKEGVNNVQKGVDTLREEVREILTEFLKRQNPPHLGLQPPQELKKSRSDTQINTTGKRFADDLFVAVRGGRLEDLEPILAQGVSVNIALGDRGDRAIHVAAREGFLLVLDRLIASGADVNVQNALQDTALHQALNRGQIPTSLALLSSGASWKIRNANGTTPLHTAVRSSAYLVVQYLLDKGADANARDKWGQTPLYKACIPPEKDKKNDFVINLKIIRLLVERGADPTLGAWKTGRTPIHGLASSGHAKELEILTKEAKTLELPLTGDSQGETPLLVAVKNKHSGAVDVLLKRGANVNARETSKDGTAPTALWYAACNPDLGTAIKLLEASADPNAKSNGMTLLHLAATKHWLELAKLLIKYKADLDAKSSSNDTPLHTAVWAKDFPIVRLMLDNRANVEAKGSSKATPIMAAAQTGSLPMVRLLLKNGAQWSYLTPQGTNAFVWSLSGGSAVCASFFLGCGQNLHHKAEGNYTALHYAARTGKMECVKLLLELGIDKQVMPTKSRVPFKVKGTAAEVARAHGAVDVAEFIESYRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP88</accession>
    <name>A0AAD8XP88_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_715333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371123.1">
        <property type="nucleotide sequence ID" value="XM_060511737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP88"/>
    <dbReference type="GeneID" id="85395635"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00266">
        <property type="entry name" value="TIGR00266 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657">
        <property type="entry name" value="TRYPTOPHAN RNA-BINDING ATTENUATOR PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="49482" checksum="521AF02643D73269" modified="2024-05-29" version="1">MSSQYYPPPPSGAQQNYPPPPQSPPANQTKFSYPAPPSQPQRSHSGSYPPPPQPSQGQSQNYPPPPQAAGQHSSSNSYPPPPQSSTSQNYPPPPQSPGHGASYPPPPQASPSQGRTYPPPPQGTTTPSQNQAQYPPPPGLSQQQQQQQQYQSPPQQSPQPSPQHQQHQQTQLPLRQPGTPDSQPQFSPPPPAFDGPPEASSLPEKQYVEEAPVDTSNPSNLVGGAPPPQHFIGATATVDDVGTFNGGSYRISHRDSNTILTVQLAMGCPLQAKPGVMVAMSHSITLRGQIKFSMKKLVAGAELASSTYVGPGELLLAPPMLGDVTSLRLTGKETWSVGQDAWLASTQGVIKDYKRQGLSKAIFSGEGLYVYKISGTGLLWLTSFGAIIRKDLMEGEKYVVDNGHLVAWNVKYIMERVASGGIISGLSSGEGLVCKFTGPGTVFMQTRNAKHFSAYLSGQANQGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPB6</accession>
    <name>A0AAD8XPB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_746830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371017.1">
        <property type="nucleotide sequence ID" value="XM_060513327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPB6"/>
    <dbReference type="GeneID" id="85397225"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056948">
        <property type="entry name" value="PNGaseA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041931375" evidence="2">
        <location>
            <begin position="27"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="3">
        <location>
            <begin position="104"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="664" mass="72603" checksum="20809E515CA31A1F" modified="2024-05-29" version="1">MLRRPVTRALALSLFVLVLNTGYVASRNLIPAAALSDYVTRQQGMIADTPAPMSTLLDAEGGQQQKPLDCFQVAQPVLGPKGPVYQALTGSFDDGKGKSPTTDPKDCKVQLMDHSFGNSFDKPFVGDYKPPGCDFNRVIVNFTATSAGRQLDRLALLYLGDTEVWRTSTAEPRAAPGIIWTYWKDMTPYLSLWKTPQKIIFDLPNLIDDRFTGPFNCTLTATFFKSDVETDSAPPADLIIPISSRNASSNTGSAWQVPEREAVSTVKFPRNANRAVFSVSANGQGSEEFWWSNVLQSDAAAFNATVGMAPDGSPWREVQVIIDDQLAGVQWPFPVIFTGGVVPSFHRPLVGLDAYDLREHEIDISPWLPVLSDGKEHTFKIKVAGLADDGQKTIVNTTVGNFWVVSGKVFLWLDEEGSITTGKPPTVSISQPDIKITGRALGKNSTGANETLAFNLDVTRMISVKGEVVSKKGTKNPEWTQKLSYTNNATLGQFGRNGFNNFIITGTDELTGMGTYKSTYSYPLIVNQTANMSASGDLSLDATLFQELRLEVEGVSVYPTGLEAYNNPTRNRQGQSSQYKTSKLSTFRNGTAVFNMPADMKSSSAFGTTRQVFRFSGGRDEARDVELYTRRVRASNNTVLSDEEKSADGREKVLTVSNPLGEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPR3</accession>
    <name>A0AAD8XPR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fork head domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_241344</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371229.1">
        <property type="nucleotide sequence ID" value="XM_060501871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPR3"/>
    <dbReference type="GeneID" id="85385770"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000030">
        <property type="entry name" value="Forkhead box protein K2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="124"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="321"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="321"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="409"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="547"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="667" mass="72740" checksum="C97C46C7FAE66044" modified="2024-05-29" version="1">MPASAKRSQRTRRDTRRDTSPARLEDSSPTRPAKRRKKVDDPPPTEPADDDESNLTADQSAQPVSDDDQLLAQVVQHFQIPKEGAPQASKDHANSIHEANGSGVQAYAKIAAQDWTFYITKLIVNIGRPSEGVTEDDEDFIHIDLGPSKMISRQHARIYFSSKEEIWFLEVKGRNGVKVNNVPMKQKSLRRLEGGEVLEAGGTEMIFVLPTEISPLHIDPLYLKRAGLSRQQMTSPQPRTDLPDEPSSALGSTIRSSRGSQFRQPIAPAPADYKRPGTPPSAIRGKPTPSQHKSPHYSSSGTLLLNSNDIDLSLDENKHIKPQYSYAQMITQAIINTPERKLNLNGIYNFIMNNYAYYKHQQAAGWQNSIRHNLSLNKAFDKVARSTDEPGKGMKWQIVPEAREEMTRSAYKGGRGGHRGSSAPSSPNNQLNYITHGPRDVNAREPASARKRKVSVTGSPPSSSLAAVQSTPDRSTRRLAPPSTAMTIDGSPLPRPRKGGASASNSFPSTSYHDQSPTLTSSYLPDEGASFVTPAPHRVHPRLAPPSTAQRPSQHMPTSSPAPFWKYADIGSTPLKPAAHFDMSPSKPSLGGIPQSSSPPPAKSPNLSPTRSQHKESSREAPSEPSNPPEIEEDQGFDLAKGFQSIGSYHAPVGRGLSVASAMNGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ07</accession>
    <name>A0AAD8XQ07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_245191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371368.1">
        <property type="nucleotide sequence ID" value="XM_060501896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ07"/>
    <dbReference type="GeneID" id="85385795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="12588" checksum="6089B974E12E0B96" modified="2024-05-29" version="1">MQGYRVHGLFSGLRNIYAGIMLPPLLLVHLSISLGSSGFLFYPSLQRLRRAKRFRRDILLLASWRRMFGEHSCCRRGKNVGKGRCVPGFKWKPRKGLVGFFCSQSETVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQB7</accession>
    <name>A0AAD8XQB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NCS1 nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_564062</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371805.1">
        <property type="nucleotide sequence ID" value="XM_060503605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQB7"/>
    <dbReference type="GeneID" id="85387504"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11484">
        <property type="entry name" value="SLC-NCS1sbd_CobB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="519" mass="56428" checksum="9F06D67F8C879393" modified="2024-05-29" version="1">MAIFETKSDISSTGGEKKSATDVERGFLGDDHAVHQADFATGTSTYARLQRLAGKLGVEQRGIERVPEDERINDAVANVGTLWCSANMVVSSFAIGVLAIPVFSLGFVDTALTIIFINFLGVLPVCFFSTFGPTFGLRQMVLSRYWFGFYAVKLIAIFNILACLGWSAVNTIVGAQLFHAVNNNMPGWAGILVIAISTLMICTFGYRIVHTYERFSWIPCAIIFLIVLGVFAHSGKFNSMLPMSTGPSEAGSVLSFSASVYGFATGWTSYAADYTCYYPASTSRMKVFLVTFCGLFFTLCFTELLGAAVMTASVTDPTFSDAYANSGIGGLLAAVLVTKLGGFGQFCLVILALSIIANNCPNIYSVSLSLQVLSRKTERIPRFIWVFVGTGIYIAISIPGYDHFESWLENFMLIIAYWLAIYEGVSLTDHVVFRRGIRGYDISDWDTPLRLPPGFAAIVAFLMGVMGAVLGMSQSWFTGPIGKLAGGSFGGDIGFELAFSFAAVSYVVLRTVEKNFFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D035</accession>
    <name>A0AAD9D035_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_69133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369200.1">
        <property type="nucleotide sequence ID" value="XM_060511315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D035"/>
    <dbReference type="GeneID" id="85395214"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="21916" checksum="C4B5C1BF05DA8EAF" modified="2024-05-29" version="1">MFPTRAPFNDGSLSSPPSFPVVRLPHRQGLALSLFHSLSPRRSHRPTQDYANCLTHFPPWSLSRTFSVSGKRTPMTPTSQLLFGVPKVSSATPAPRSICDTPSPALDFAFPGDLVKEKDDIRSSHSGIPAHPQQKQDPAPQSSAPVLQDTTGMKVIFASLSSRGCLPVIIWRTIFWPCTFSMLPLQRWQGSRGFSPSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D107</accession>
    <name>A0AAD9D107_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">COP9 signalosome complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_716157</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369710.1">
        <property type="nucleotide sequence ID" value="XM_060511824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D107"/>
    <dbReference type="GeneID" id="85395722"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000022">
        <property type="entry name" value="COP9 signalosome complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="232"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00067814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="476" mass="52786" checksum="E7B7DF8C345ECE2D" modified="2024-05-29" version="1">MAAASANASLDSNALLTFFTQMDDQGGVIVRDTPKLDLDLYIQNYTGRTRFERLFLIGRTCVPLCVDALKAAVAEAKKGQDTQRYRDVVELIQVAAPLEPEATFDQSWVELTDRANNAKTHALEGELKGYKMNLIKESIRMGNEDLGRHFESIGDLNSAGEAYSRMRPDVSTSKHIIDVGKHLVNVTLQRREWPMVIANLSKITGVQNGDEEKGLQPYVKIVQGIALMGLEKFDEAAKSFLQTDAGKEGVDYSNIASPNDVAVYGGLLALATMDRKELQARVLDNQNFRTFLELEPHIRKAISLFVNGRYSACLAILEAYRADYLLDIYLQKHVPTLYSQIRSKCIVQYFIPFSCVTLSSLEDAFAVPGKPLIDELVAMIRGGVLQARINTIDKTLVAVSPNPRATLQRMVLDTIDAYERDATERIRRMSIIAADMEVKTMRKGNTHAGAQGIDELWFEQSNRPTVAGGAGGDNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2J6</accession>
    <name>A0AAD9D2J6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_343452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370924.1">
        <property type="nucleotide sequence ID" value="XM_060502472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2J6"/>
    <dbReference type="GeneID" id="85386371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF13">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="28133" checksum="72A89B7685004EE7" modified="2024-05-29" version="1">MSPIPTALITAGSAGLGAATAKLFARNGYSVVINYANNSDRAEALVKELESLSSASTSSSSTEGSQRQHFHAIKADLSSRTETSALVKSAADALGGRLDVLFSNGGWTRLRNIADLDDNVDEDDWDRCFNMNVKSHLFLMHAARPYLDEAEGAFITTASLAGVKVSGSSLAYAVTKAAQIHLVKGLALAAGPRIRVNSVSPGLMLTRVIQEWGLQFPQEKQQAARDRTPLKRLATVDDVADQVLCFARSRSVTGANAVIDGGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2M8</accession>
    <name>A0AAD9D2M8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_597796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371582.1">
        <property type="nucleotide sequence ID" value="XM_060506918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2M8"/>
    <dbReference type="GeneID" id="85390817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="84" mass="9727" checksum="2E1E683319D7A14E" modified="2024-05-29" version="1">MADKLRNQQELERLQAKYVGTGHPDTTSWEWKTNIYRDTYSSIAGHPPMLSYMALAENEPTQLLRARLIRKMMQPAGPPPQRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2S2</accession>
    <name>A0AAD9D2S2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_786864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371717.1">
        <property type="nucleotide sequence ID" value="XM_060515652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2S2"/>
    <dbReference type="GeneID" id="85399550"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052032">
        <property type="entry name" value="ATP-dep_AA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041472">
        <property type="entry name" value="BL00235/CARNS1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585:SF2">
        <property type="entry name" value="ATP-GRASP ENZYME FSQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585">
        <property type="entry name" value="FUMIPYRROLE BIOSYNTHESIS PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13535">
        <property type="entry name" value="ATP-grasp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18130">
        <property type="entry name" value="ATPgrasp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="328"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="678" mass="74895" checksum="45773C6FAB19C8FB" modified="2024-05-29" version="1">MGDIIDLPDQTKSARNHFQVLSPTNEAVYEFSWKAYTNPIRGNDWQTIDVVFDITPTDASNNTRLSHAWDDDWRFSISSSKLATDFLSECLRASLKNGLGCGPRVAKLIVPLVEGQIVRSDIIPLRFIDCEFVDARSSLSEPLRFFSGLPVQVSQLDDLAELLEVSAGGLILQALPPGIGSLEARSFSQFVEAETENRLSFPWITTPTAPKTLVIVEGSRQHPSDGGTGPNIYLAAMALGIKMVVLDVPGHWLEGLEYEHWREAFIPIEMSQPPDEGFADRIAQAVATYQGKVDGIITFCDSFQHQVALAAQKLGLPSSKPEALMTATNKYATSVFEGRKSHLVSSTQEILQVAATHGSSLFPCIIKPCNGWSSEGVFLINNNTELIEAMGPLDALSKSRHGSEFVIERYCAGPEVDANFVLLDGEILFFEVCDDFPKSADTNGSSFGGAKTFIELDSVFPSKLPESEINLLRICFHNTLLRLGLRNGVMHLEGRVDNSTVEYRTEGGVLDLRPRAADTQSRGAIKSPEAWLIEINPRPPGMKGTQVIESTHGVDYWGLGMLIALRDVERTKALCHAYRNGPQYTCVMVFIPADYDFSSAEGIFDSGDICDDLFNRRPDLAKNVSRYGCLVKKGQKVAHPSHGVNSFLAYFNVFSRKGREDALRLAKIVREEVRFSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D359</accession>
    <name>A0AAD9D359_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_646308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371404.1">
        <property type="nucleotide sequence ID" value="XM_060509951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D359"/>
    <dbReference type="GeneID" id="85393850"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="17833" checksum="9310D789E55FAE77" modified="2024-05-29" version="1">MRRTARLEASSGIHRLRLVRARLGKVICSWHQYQGIFLVLPRAASTRSPAPEMGRLSWSADFRLSVELKLVSCGYLPRFPVSPNGRCQAFSRKDCKAKPSKPSRVGGGAWGRGPQLRGRQLQLSHAYCSSCRVVQTPQLNLTCRQLGENQGDTRRVWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D367</accession>
    <name>A0AAD9D367_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_246818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371405.1">
        <property type="nucleotide sequence ID" value="XM_060501908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D367"/>
    <dbReference type="GeneID" id="85385807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="17243" checksum="637090DC643E28B0" modified="2024-05-29" version="1">MAERFITLAFVSLVYWYPPCGQYLAWLAMARRPRIQVHSRPSPEYDCGCTSTRLRYSVLRTEIGRSPTAPASCWELAAADGVGLWRWSSCHYVERHRSFLQAGPSPGSRTALPARRLINFQSKREQVQRCRASWHDCPWHACMPWCGLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8L5</accession>
    <name>A0AAD8U8L5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_798362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000383">
        <property type="protein sequence ID" value="KAK1700801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357004.1">
        <property type="nucleotide sequence ID" value="XM_060515929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8L5"/>
    <dbReference type="GeneID" id="85399827"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1700801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="50" mass="5703" checksum="F64EF07B06F3D86A" modified="2024-05-29" version="1">MRYFGACYYIKISRYSIILIATLEPNPVPFLIAALRATTLPRLQFRSPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8P6</accession>
    <name>A0AAD8U8P6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359547.1">
        <property type="nucleotide sequence ID" value="XM_060506266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8P6"/>
    <dbReference type="GeneID" id="85390165"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="347" mass="38731" checksum="44C765A18E3455DA" modified="2024-05-29" version="1" fragment="single">LSLPLTMDQHVEAPVFVPSNIKNQDSTTSSDDSASTNYPNLSCLRGSGMLDTPAVLSPLRPALRLGCPTPRPSVNTTTNPNSRWSAVASPLSFEHLYTENAYLTASLSKQGERENDLMRRLSTLQENVDSGLPPEERRKARKKIALLKSKILDATAQKKAILLRLGDIYVELQSREIWMQIQNELYERRSAWWSVDSPSTSAYATTPSDVTSMMPTPLDVASPVFFPAGCHPVYNTWDVAAPRFEEHWYEVYDTIPAESWAHLGQPPEVLAKDLGNHGLQFVYWLRAGDLRQDVIEGQDQESSQEIELPTSGRRSSLPSLKSLWSGAEGLRRPGEKANEPVSHIYQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U907</accession>
    <name>A0AAD8U907_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000261">
        <property type="protein sequence ID" value="KAK1704536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357450.1">
        <property type="nucleotide sequence ID" value="XM_060511024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U907"/>
    <dbReference type="GeneID" id="85394923"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14913" checksum="A5FB08DCB1FF5A12" modified="2024-05-29" version="1">MGAFVFNSTPGKPRFSSNVVAFKPPLLANKFIYTIGFPFGAIVSGMVYGAYAVSVGREKNVISKTRNALNDEMLWHVTGSPRMYVFFEADDLIAWKDVEDHAWESDELFGLDDVVARFRNSGHYSHARGNKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9F3</accession>
    <name>A0AAD8U9F3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_758800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000268">
        <property type="protein sequence ID" value="KAK1704187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357394.1">
        <property type="nucleotide sequence ID" value="XM_060515094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9F3"/>
    <dbReference type="GeneID" id="85398992"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="2">
        <location>
            <begin position="177"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="643" mass="71154" checksum="52EC5C3DE0216132" modified="2024-05-29" version="1">MIVNTIDDVDDWLAAVLDGEDRRPKFGLLDLNQLISSNTDITDILAESWRTSTTSKTVERLLSVDEPSESLEDGEAFKKFELGIREAIKVAAKVSADQISIVDDGLDMITPTYTNVSQPDCSPAGTITLAKQDVDSTLSLYSFQPTFPGNALAMSQAPTPQRHTCPPQVPPNWAQLLDVYFANTHSWLPMVQKHDLLRLVYLKANSDKDANPSNAIHNGDLCFLWTVMAYSLRQSGSLELSKVFLESATDILAKDNGKYKIGHIRALLIVALIRLEEKDNGAAWLAIGQATYSAVMSFLAATVDGSLHKDEGTGRTLMCVFVLDTLIASLAKSRPYLDSSDAQRFGLLATESMEEWEPWHSKDLDDQAQPPSHVPGLVLSMFNSFFLLVGILNDVMRLEMGSDNIGRCYHIIRDFEEWRKHHLPDCGNQHDVVTSPQDTHLRLACASISETLRTKVQRLKGTPYGVPSKGSSEILVQEQSLLKLLDTTKTFRMPPTSVVFLTSLETACDYRMSNTQGLGRPPGDLQPLKTALSDAQKRISRRHSLSTMSRSEIAESEPATMEAIADYIPVHQTDLRQFQPEAQVSFSQLMDTATENIGGELFMSLADLDSADWSANPPEFMRHLGVVGDIATDIQSFFDQEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAW9</accession>
    <name>A0AAD8UAW9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_174991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000205">
        <property type="protein sequence ID" value="KAK1707751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358129.1">
        <property type="nucleotide sequence ID" value="XM_060501485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAW9"/>
    <dbReference type="GeneID" id="85385384"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="21041" checksum="21E11962FE81EDE8" modified="2024-05-29" version="1">MIIASYTYQPCIKELINGAKPPSRIHPSPMAASPSCTPNTTLHCPQDSLCPCKTTCIFVNPSPPHHPSMFLPDVLFSYPPFSEVESCSRNRQVLVDVRVLTSFLAWLLAWLLAWLLIRRRATEDHVVHIRAVPEDGVRIEATFFGPAGLIIVRFLFECQALQINGVQNSGPRILQPSVRVAPARDSSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB38</accession>
    <name>A0AAD8UB38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358545.1">
        <property type="nucleotide sequence ID" value="XM_060509556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB38"/>
    <dbReference type="GeneID" id="85393455"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="766" mass="81963" checksum="9DBF9B50860A61EB" modified="2024-05-29" version="1">MKMIALAETGMDDAEAMAARQLPDLGGSNVYRPTLAAGPARHLPETRRPNATNFQGMQTNQSGILMPPGSQLHRYPSTRAADEPRANVQGSRVTLTTPSTARPAAAGSSTARAGSTEATNMPLPPHLRAKSTQNLPVAAPNTAISAPTPTSNASPSVKGKEKEKSEDTTKQPQLADENSEVHWAGRCKAQARGKEHDIVIKLKTIESDEHPNGHVVCIIVCPGVFDQAHSMNDYTLDFHKNHMCIVSFGASASRPSMRYSLKFDDSETAADFVQRADMLQKVMKYLREMAASQDEVDTGAVAPVESAAPEAARPTQTAVQATEVAPMKKDHGEEDLTDAFSNLKLTNVKGSPMYTTDRPPRVQYSPEQLLERRSSAEAPAGIKDVKIPLEKDSRSEFSKLPPHLQQNQKLRASQPNNEAAKLMDWISGTMQTQTGTGDVSQVSMPGLSEAVNHHKAVATTPQFSTGTQIPRKESTESNLDKNTDSKAENKENSAIKLEVTDAPKNKIDIDAETQVQVQSSIAKTSSDSTQAYGENTAKEHVPNGTAMESTNPFDAGASTEIEHAHVQKASQDVLPKEPLIPSKTAESDKGDAMSDASHDSAVEFEAPVKAEPDVTAPAPTPVKSPETAPAVPFNPTSYIMPAGIPMPQMTPGQVHYATQMQPQMHPQAMIPGMYPSGVIHAVTVTYHISYPDSEVGMGMNGPVHQNGGTFSPNAEPFQPIGLGHGQVPRQQGSDQPRTRRGLGGSMFATGYSAAKFPGSFTGAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB65</accession>
    <name>A0AAD8UB65_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_27487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360912.1">
        <property type="nucleotide sequence ID" value="XM_060502087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB65"/>
    <dbReference type="GeneID" id="85385986"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042037523" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="15308" checksum="11637F47C21AC6CD" modified="2024-05-29" version="1">MARSILAVLAVAGLASAGSLLTPRQDNETKPAVDITALNKNVSATAGSGAVSAAGTLAPFGGIGVGCGINWAEGQSFGGGLQSGSEAFGLGGGFTITKDTMNIGLGIGINPINFNSSVSYEASTNGTVSLVFTSTSAIKCEETTVDGVKGVKCTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB91</accession>
    <name>A0AAD8UB91_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_797498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000195">
        <property type="protein sequence ID" value="KAK1708431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358309.1">
        <property type="nucleotide sequence ID" value="XM_060515897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB91"/>
    <dbReference type="GeneID" id="85399795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="91"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="41873" checksum="4427684A75988174" modified="2024-05-29" version="1">MAEDQNTTDDSHRVPELPLLSKVRYGATAFAIQNFLVKPALFVRDVKAHVIPPENRPEIVKTYECRPYLPVRVFFPKCFDKTSKDKLPVLFTIHGGGFVLGTPNDNDDWNQTYASQHHSIVIGLNYAKAPGNPFPKPIHDCEELFLAALNDDSLPLDRTRVSLAGWSAGGNLTLAVAQLETVRKHLTCIVPLYPAADLSITGEEKAPTRQYKPELGGFRAKEKDFLQGIAPVFDWAYKIPGEDSRNPLLSPTFAPKEALPKQVFMIGCELDMLAHEGQRLIHKLAGRPPPPAKVGKPEVVGDGELVLDDEVYHFEVSGADGSRYRWLLVPDTVHGFDQHLDGIVRDPVLLEDAKIKTQKTIKIIGEWILQAPPISEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBI1</accession>
    <name>A0AAD8UBI1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">KR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_797178</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000174">
        <property type="protein sequence ID" value="KAK1710059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358755.1">
        <property type="nucleotide sequence ID" value="XM_060515885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399783"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="8"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="987"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2541"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="450"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="987"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1150"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1019"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1710059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2624" mass="287823" checksum="702FCA2BF46ABC5A" modified="2024-05-29" version="1">MDTMKDQIQPIAIVGLNLKFPGDATSAESFWEMLENARNASSKVPSTRFNIDTFYHPDPARLDSMRVQKAHFMKEDPRAFDAAFFNMSPAEASILDPQQRGLLEGTYHTFENAGLAMERVAGSRTSVFCASFGRDSDAIVARDPEFQSRYQATSSGSSMLSNRISHFFDLRGPSLTVDTACSSGLYALHLACQSILNGESDMSLVCGSNTYLTPECMSFPLSNAGFLSPDGRSYSFDHKANGYARGEGYAFVLLKPLSKALADGDIIRSVIRATGANQDGRTPSITQPSATAQVELIRRTYSAGGLDLSETEYVEAHGTGTPVGDPIEVSAIGEVFRPHRSSPLWIGSVKSNIGHLEGASGLAGLLKTVFSLERAIIPPIADFEKVNPAIDVDALGVQFPTRPTAWPATPSGIRRASVSSFGYGGSNAHVVLDDAYNYLRIRGLTGNHLSVAKSNNSHKPRVANSSTSVRTAEDQAPDAGTPDSISDVSDDSGVIINYESEAEHSSFSLLTFSAADEDGPRRQASALQDHVATQQISRKRAQRVFLADLAYTLSQKSILNWRAFAVVKSEANIGNNLTEILSPVTSVLSSKRPELNFVFTGQGAQYPRMGLKLMRYEVFRQSLMDCDEYLRSLGCEWSVFTELRKAPGSSRIQKPEISQPLCTALQIATVDLLRTWDVTPQSVCGHSSGEIAAAYCAGALDRQSSWKVAYFRGVLAGRLASDGSRSQTTMMSVGLGEAAVRPYLSNRLSVACINSPANVTISGPTKEIQVLFERLEKEEIFVKRLPVDVGYHSPAMEVVAAEYQDRIRDIGAPTGLAAERLRKESLVSLYSSTEGKLTSFEAVTSPSYWVKNLVSPVLFSCALEAMTGSKHGGPHFLVEIGPQSALRRPVQDTLTPHLGNKATKKWQYVSVLKSNVDDDQSLMEALGSLWAAGIPVSLCKPNQESTQISRKPKILVDLPSYPFNRSREFWEESRLSRNYAKRPYRRHALLGIRDRDWNPEEGSWRHLIRFQENPWILDHALNGSPLYPGSGMLVMAIEAARQLATPVESRIRGYQLDNVRFLRAIDVDDSERGTEAKIVMRRRRQATNTSGQQLCYDWRVFGTSGDDWNECAYGSIKVELEPEQALGSEQAAASEARRYRFETSIKEQLQVDVDKCRLVVHPSQLYKNMSKRSGFDYGPYFQLLKNISYDREGHATATLSARDYTSSMPYAGEDPCVVHPSTLDAVCHLQMVALSQGGWNAVPTMMFSHLRKLWVSQKLFVAPGNPQLRAATQETMRAFREAECRTLVTFADSNEPVLVLDGQRGTAITSLKSADAAAASQGDSGQKFYGLDYKPDLSLLTVDAKSRYFAAAFKEDTRCRAPPRELIDRADAIALHFIETALEQIDQEDKPLQFDNHLARYVKWMRRVHLNRDTWTLESRGLSHLRIQEILDEADGEPTQKLTKKVGEHLHSILRGEANALQVIFEGNLANEFYHSDIFATNNSNMGAYINVLAHANPNFVCWKSELEPGARPVGFSLTWLHKGLKVVLQRLHMTFKKLDLEKHPNTQGFAEGTYDVVVAGNVLHATSDLIQTLRYVRGLLRPGGVLVLGETVNLDNVRDGLIFGLLPGWWLREGQWWSTNKEYQDQGPLLTEEQWTTVLKEAGFPGIQMAFRDHEQKPHHRVSIIITTRPENESLSSQPSRVESPYRIIMDPTSAIQTSVAESLRSHLVSGSQPREADISSIVDISSGDTKLTGDVVVISLLELDTSVLSSVAAKEFEAIKKICLDTRFTLWLTYGGAPKATNPAAEVAIGFGRSVCSERGDQGFVTLNLSSRPETPTAVTSAVDSIMRVVERLHNVSCPGTDNESEFSEDNGLICIPRLMPTPHMDQALSIKQSGGRLKSFTFNGADPKPHISITIETPGLLDTIFYAEGTEADNELQSGDIEIEVKATSMNFKDFMIALGQIPGRSFGFDGAGIVSRVSRESNLRPGDSVLFCSSTGGGFGTFVRCPELQTEKLPTGMSFQVAAAIPVVWSTVVYSLDHIARLSRGETVLIHAAAGGVGQAAVQLAQLRGAKIFATVGSQAKRELVKQLFGLSDDQIFNSRDETFAHDVFHATEGRGVDVVLNSLGGELLRQSWECIAPFGRFIDIGKADIIANNTLPMGPFNRNVTFSAVDLVVVHEEAKPLMKKILQDVTRLFKENPHLHEPKPLHVFSPTRLEDAMRFLQGGKNTGKVIVDYASATDTVEYRPSQLQHGYNFEANATYVISGGLGGLGREIARWMVSRGARNLLLLSSRGAAGRPDALKLIRELEATDGVTVLAPACDIVDRKVVEDTLLKASRELPPIKGCIQAAMVLRDDMLAKMSHSMFHETLGPKRAGSWNLHQLLPNDMDFFVLLSSFCGIMGNRGQSNYAAGNAFEDALARHRVAQGLKGVSVDLVLVAEAGWANVNYESVTQSLRAGHDNLTQAQLMELLDLLCDPGYDCAKPGAAQVVNMVDSAADLARMTQQGLLDWMQKPVFSNLLRMGETEASGNGRGAGGGNGDGSDDVNRLALVKAAPDLSTASEIVTQGLVQKLAKSLSVPIETLDVGKPAYVVGVDSLIAVEVRYWFMKQLLVEVPVFEILKNQSITDLCQQVASKVLQSSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBZ0</accession>
    <name>A0AAD8UBZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_640722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000174">
        <property type="protein sequence ID" value="KAK1710047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358743.1">
        <property type="nucleotide sequence ID" value="XM_060509513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBZ0"/>
    <dbReference type="GeneID" id="85393412"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="125" mass="13690" checksum="F6D1A002136C1784" modified="2024-05-29" version="1">MMSTGCDATPTPSGSRCEVLRQVERLGGAQTMIDRDDLATGTTTPLYVLHSNKENKTVTVLHTDPRAQVSGQALSTAKYHSLSSKMDVILRGVPIKMKTNTMGNSHRFVHQGLSYSWSVPIRACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC29</accession>
    <name>A0AAD8UC29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_642935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000211">
        <property type="protein sequence ID" value="KAK1707352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358040.1">
        <property type="nucleotide sequence ID" value="XM_060509648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC29"/>
    <dbReference type="GeneID" id="85393547"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF190">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1707352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="57895" checksum="B5366C5379E9CECD" modified="2024-05-29" version="1">MNTQLLLAFAGFALLAQTLVSFVQWLRSPLRSVPGPLLARYTDFWYFHRLKQGRFEKVNQELHKQYGPIVRYGPNRYSINDAEALKTVYGHGTQFQKSEWYIPFQPNEDQWNVFSDRSIQRHAHSRRFYTNAYSMTSLVNYEPYVDECGALFSQRLSEFAKAGSTVDIGHWFQCFAFDAVAMMTYGKRLGFLDRGEDIAQVIDNINKSLVYSSLTGIFPSVHMCIAPLVTSITKRLGMGAKMMYVIDFTAQTIAEERASPKTVIEVKGAEDGAAVGETFLTKFLAKHSSDPIEFTNWHLLIGCASNIFAGSDTTGISISAIVYSLLKNPDALAKLREEIEDFTCRGELSQAPTFKESQKMPYLQAVIKEALRVHPAVGLPLERIVPEGGATIGELFFPAGSVVGINSWVHHRNTALFGDDAEKFNPDRWLIEDEEKISVMNRNWMPFGLGSRTCLGKNVSILEMSKLIPRLIRDFDFKLEGAAATPGGAWKTRNAWFVKPQNFHVKVKSRTTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC57</accession>
    <name>A0AAD8UC57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_591570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000174">
        <property type="protein sequence ID" value="KAK1710048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358744.1">
        <property type="nucleotide sequence ID" value="XM_060506447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC57"/>
    <dbReference type="GeneID" id="85390346"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18833">
        <property type="entry name" value="GH43_PcXyl-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF17">
        <property type="entry name" value="BETA-XYLOSIDASE C-TERMINAL CONCANAVALIN A-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="7">
        <location>
            <begin position="337"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="557" mass="61866" checksum="F818E9EE557A0FDC" modified="2024-05-29" version="1">MVLAQNSTFTNPVLPGFYPDPSCIFVQELNHTLFCASSSFLAFPGLPITASQNLQDWSLISNAFSRQDQLPDFAGPLTETGGIWAPTLRFRNGTFFLTSTLVLDYLPVNDSSRWRNFILTTTDPYNSLSWSQPLFFEANGYDSSLFWDSDGQTYVTWAGYPDVLPGIFQAVIDLKTGEIGQALNIWNGTGGEAPEGPHIYRKDGFYYLMIAEGGTFLGHMETIARSRNVNGPYEPNPGNPILTNANTTEYFQAVGHADLFQDVIKNWWGVGHAIRINFDNKAIPMGRETVLFPVTWDTGEWPVMSPVRGRMSGWASPSPVNNLVHSYTTVVVDDNIDFVKKERPKHLVHWRYPNDTLYNFTPTEEHCGLQLLPSAGNLSSTKYNDGASDAVTLLLRRQSHSFFTFSVDFDISHMSDVDEVGATVFISEATHFSLGITQPASAETNGTARKAAQLRFRGNYNDVSTERVVPTMLLPVLEEQRMTLEIKACNTTHYAFSASPTAHQSAMKIVDYAPAALLRPIFTGALVGIYATSNGENSRGHICIPGWRYQGDGQLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCL3</accession>
    <name>A0AAD8UCL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360358.1">
        <property type="nucleotide sequence ID" value="XM_060509173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCL3"/>
    <dbReference type="GeneID" id="85393072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042246447" evidence="1">
        <location>
            <begin position="21"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="103" mass="10967" checksum="C46A5A4CEB182728" modified="2024-05-29" version="1">MKFSSVIISIISLTVGTAIANPARLENRQKAPGVGDPNAQCDGKHDCCFSSEAACFRQYGTLSGNIYCPLHKYCATDYNIPRTKCNADCCSISNGLGRGCPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD05</accession>
    <name>A0AAD8UD05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_639421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359149.1">
        <property type="nucleotide sequence ID" value="XM_060509423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD05"/>
    <dbReference type="GeneID" id="85393322"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="58" mass="6709" checksum="432B538FE1255832" modified="2024-05-29" version="1">MVFQYFVLRDYGSLFGPPLTMTFFCDSEEAAYRELDRMLVIRAAQVGRGTPTTKEERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEE9</accession>
    <name>A0AAD8UEE9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_784044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362446.1">
        <property type="nucleotide sequence ID" value="XM_060515602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEE9"/>
    <dbReference type="GeneID" id="85399500"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF29">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="1">
        <location>
            <begin position="28"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="48997" checksum="6F5BC41973637741" modified="2024-05-29" version="1">MSQALPLQNKGIFRNLPTFPSDVTDLTALITGANGISGFHTLRVLLDAPQRWKKVWIVSRSPLSEKMMSFFSAEQQKRIEHISLDFLADANVIAQGLEERQVTADYVFFYSYLQPKPEPGAAAWSNAEALVKVNSALLQNFLDGLEKSSIRPKRIVLQTGAKNYGGHIGQAISPFVESAQRVTSEPNFYYPQEDALFDHCARTGAKWNVFRPSWIIGAVENAQMNAFYGLGVYAAVQAHLGRPLEFPGTMAAWLKDHAHSHAHLTGYLSEWAVLNEHCGNEAFNSSDQGSFSYALFWPELAKWFGISEVGRPELDESKMQKISMPGEPPIGFGPRASLKFSWSFVAWAKEPENHEAWKEIMKKHNLLNDPFEDPEGQFMFTDVAVLPDAYGRLSPNKARMMGWNGFVDTAEGIFATYREFGKLGMLPPMAVDEARPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEK2</accession>
    <name>A0AAD8UEK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_461148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361547.1">
        <property type="nucleotide sequence ID" value="XM_060503237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEK2"/>
    <dbReference type="GeneID" id="85387136"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF236">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1719463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="34724" checksum="65008B0C58801B30" modified="2024-05-29" version="1">MGSALSNMFPPKASFTEANLPDQSDKVFIVTGSSGGLGKELTKILYQKNAKIYMACRSEAKTAAVIKELKELYPNSQGHAEYLHLDLNDLTTIKQSAQEFLSKETRLDVLWNNAGVMTPPPGSKTAQGYELQLGTNNLAPFLFTHFLHPVLSGTAKVAPKDSVRVVWVSSSTAAMAPKPPIDFNNMDYAKDEGQVQKYARSKAGNVLHGTEFARRVSGEGIISVSLDPGIFMTDLQRTMPLWQRIIVKFLAHKPINGAYTELFAGLSPTITEKNNGGWVVPFGRLAAGREDLRDKELGKKYWEWTEKQLKPYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG44</accession>
    <name>A0AAD8UG44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_754512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362312.1">
        <property type="nucleotide sequence ID" value="XM_060514483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG44"/>
    <dbReference type="GeneID" id="85398381"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="21096" checksum="088D8CF95522685D" modified="2024-05-29" version="1">MEVIADVSRLATAFVTGHGLEDYSRPALPKSSGTSHGENARIGHPDSQGNLTVIDNTLSSAALEFICEELCSPLCDHIPSVMRIVDSILKGNADLQELTNAFQYYLARITPTDVQTLTEGAEDIYDIFVATPSKLEDLIDAIKIDLGTLGVNGTWRLLRAGLSIYFRLSPSDEHNLFRTLGDIITHFDASNASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH69</accession>
    <name>A0AAD8UH69_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_705981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361548.1">
        <property type="nucleotide sequence ID" value="XM_060511519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH69"/>
    <dbReference type="GeneID" id="85395417"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF5">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="370" mass="41487" checksum="BB287CC6EABD5A5A" modified="2024-05-29" version="1">MPRRKMPDAKDRRKRQNADAQRAYRARQKTKVRHLEQMVAAAWVTQEPAAQDCVKEVSICPPTRYAVAESSNNKVEAYTASCNLTASDIYQALLSLSAHENKKGWGIMVRENFTLRDVVKYGLIAIGYSMDPVLYESALSLSSREWIAAVKARCGNVDMRQVVVAGLTILAHLTAPNEQPALEWLQPTYPRPSRDVIHLNSMSYASAMRAIAAQLSITTEYLMDENAQSLFYSVDHSRLSEHDNDPSDDDTALQKITPDLRPTFIQRSRAHHPCFDLIPWPSFRSSAIVLASGASPQIDEDDLCIDMLGGGVRCWGSAMGSMHGRGNGVPWDGRSWEAMPWFLEKWKGVIRDDKDGMVQTSAWWRGLRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHH2</accession>
    <name>A0AAD8UHH2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_742365</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362987.1">
        <property type="nucleotide sequence ID" value="XM_060513109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHH2"/>
    <dbReference type="GeneID" id="85397007"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="12">
        <location>
            <begin position="245"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="898"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1722932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="954" mass="106736" checksum="363D1D660D238529" modified="2024-05-29" version="1">MLIKSYPGGAAVTGSLLITFLVTFLLITLSLPPSKSFIRLTGVFALATLTYALQLASSEWIANPHWRSAIVPLLWIQFMSASELVLVRKWDGIWESDARTKSMAGFTPSSASLVARTYESLMLLWKLRRIGTRWQVKHVPGLQQRSPHPPESRVAFVLKRSLKILVAFQVLSLMTQAPPPDPNFVGRDKQALAFQGLVRLSQADITFRIIGTLSFWACTALINLLMFEVTCLGFVVVFLCKVEDCPPLYGDFSSASTIRGFWGTSWHQCLRSGLTGHADVIEHHIFPFRQRLVSRYLRIFISFFISGLIHHTSDIAMGMTAKNAGAFMFFLLQPIGIIAEDAIQAISKQAPVCHSASRVRVFVGYLWSPIPALIFLTFTLVYYIYLKGFPRPLTGIPYNESALKSFLGDLPAFQHARTHGKGFTVWMRDLAQKHGSPMVQVFLGPFAPPCVVLFDYRESYDIVARRTKEFDRCRRDAETMSTILPEHHLSMVSADARFKGNKDLVKDLMAPGFLNEVSAPEIYSKALSLIELWSVKSKWAAGRPFEAHHDLQNAALDIIMSAAFGETSNGGVLRQHILRETGHRPFLVPTDPKEPACFKSLGLPTEYQATVDITHFMGRVVTSPFPKQFAWLLKTFTRVSSVFVKKDQFIRSQIQKAVSSLSDESLQGGKAAKSALDFIVLREVTAAKKSGRKPSFTSKRLEDELLGYIVAGHETSASILSWAVKFLADNQKQQHTLRKHLQAIYPDAVEERRQPSVTELTTVTAPYLDAFLEEILRLSRTASILTREAVNDTIVMGKFVPKGTTIFIFTQGASYVQPSLGVDEQVRSRTSQEAKRVPDWLSDDVGKFCAGRWLVPKTGASGFSEEFVGKEDSWTLSDFDFDPQAGPILTFGGGPRGCFGRRLAYLELRMVLALLVWNFVFKPCADNLSTYELRESITVEPKDCYVNLQTSENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP7</accession>
    <name>A0AAD8UHP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361716.1">
        <property type="nucleotide sequence ID" value="XM_060514562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHP7"/>
    <dbReference type="GeneID" id="85398460"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="11675" checksum="A169397497C196E9" modified="2024-05-29" version="1">MPFRKHECIADKSFEDNTASTYAGGNSNERVSNERVSNESDIEAGVQVKPAGPRQKHPTDSISGHQIFYIFGLDGVGAAVLSGGINFAIAYGKAPQHSAELKLLANQAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIN9</accession>
    <name>A0AAD8UIN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial distribution and morphology protein 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_579742</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MDM31/MDM32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364018.1">
        <property type="nucleotide sequence ID" value="XM_060505279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIN9"/>
    <dbReference type="GeneID" id="85389178"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000001">
        <property type="term" value="P:mitochondrion inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012571">
        <property type="entry name" value="Mdm31/Mdm32"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31068:SF0">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08118">
        <property type="entry name" value="MDM31_MDM32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="746"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="135"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="620"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1723963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="767" mass="85030" checksum="54A2C9104935B81E" modified="2024-05-29" version="1">MSNASSTLLGRRFWSCACGSAQTLGLRGTTITTATTRNTCLKASQSTVSPSLPRSSTFRRSIHSGSQHSFPRPNIHNARRSYTGSGLLLVGFTTELTPTQASAACAVAAESATSTSLTKKSNIYQLARQAWRRGIHTDSRGTVSPAERRHHSSKSGKHEEKSPTTQTKQDTPKAGEQGKPEAPDPDAESIASTVSKYLHIPKMPHRPTRDELLAAANGFLGRMKVRFKWASIRSMRPWNIDEWGAFVSWFLFGHLVWILVGTTTFFSLIILSINTVFAQETLAKWVGDSLTESAGVTVVFESAIVPKWGDGVISFKNVFVSRRPGQVKSSVSKGSSESAAAMAATGNQPDQDGQVLEEDDGNYTQYDVSIATVNVTLSFLKWWNGKGFLKDVEVKGVRGVVDRTSVQWSDEVVDPLSYRHTHEPGDFEIDSFKLEDLLVTVHQPKGFRPFSVSIFSCELPQLRKQWLFYDFLSATHMSGSFDGSLFTIHPRQVHGTIASENGDMAEDVGEPAAWKKFSRLRIDGLKIDHLNRGVEGPFGWIYEGNVDIVADVMFPADVDDGITKAMSDLYDQLEDVVISNRMRLLQKDLLDIKIVGSSASDLWGSTPSKGHLSQAIPELTEEVPEKPTESEFTDPSSSSESSEEDRRYLIMDLRIHMNDVKAAVPLFTKDISYINQALVRPIVAYINAKKTYIPINCRIVKRHTDFDGSWSIFDCGLMDDMSAETYEAFARDIEDQQSRVRRLKKVGFWTLSLAVHALFMGMAGNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ13</accession>
    <name>A0AAD8UJ13_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin NUP49/NSP49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_652895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363737.1">
        <property type="nucleotide sequence ID" value="XM_060510565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ13"/>
    <dbReference type="GeneID" id="85394464"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024882">
        <property type="entry name" value="NUP58/p45/49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437">
        <property type="entry name" value="NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13437:SF2">
        <property type="entry name" value="NUCLEOPORIN P58_P45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="47668" checksum="017E776B58A16391" modified="2024-05-29" version="1">MFGRSAGGLSINTGAANAGTTSTATTSAPSGGGGLFGNSTAATTQPATGGLFGGTSTAGGLFGNKPSTPQQPATGGLFGAAPTQQPQQQQSGGGLFGGAQTQQQQPAQQTGGLFGGATTQQQPQQQQSGGLFGATPAKPATGGLFGASTAQPQQQQQSTGGGLFGGGNNAQQTQQNQGTGGGLFGQSQAQNQPKPGGLFGQTQPAGSSAPGLTMGQSTTQQSVPGVRVDMSNIKGTTRFNDLEQSIQSEMENCDLMIQRFMAHASEIRGFMAAHGGDLAQLTNDVNWLQRKYEGVKTTLDEDIVTLGHLKDLVKSDADIAKMAFAGADQLKLPAHYHQTWLTRGGSGGNTTNGNQDRNLEDVLTLFSNEADRLKELSQFQVQKIKEMEQHMPGVEHGLYERVRSLRDQTQVPAFNMVLDLLETIKMMGDKIYEAAGSIVDVREKLTQLQRQYPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF1</accession>
    <name>A0AAD8UJF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_719940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364423.1">
        <property type="nucleotide sequence ID" value="XM_060512229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF1"/>
    <dbReference type="GeneID" id="85396127"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="481" mass="51798" checksum="D9FD56D6CCB2AEAE" modified="2024-05-29" version="1">MPVSGSLSNVDWEPSFSTLAVHGGQEPDPVNGSRAVPLYQTAAYNFTDAADGASKFAWSKDGYVYTRMGNPTNSVFETRMAMLEGGVGAVAAASGHAAQFMALTNCCEPGQNFVSTSWLYGGTYNQFRVYMKKFKIDVKWVVGNEPADIDAAIDENTRCVYIETISNPKHSVPDIKAIADVAHKHGIPLIVDNTFGMGGYLCQPIKQGADIVTHSATKWIGGHGTSMGGIVIDGGHFDWSASGKFPGFTEPADGYHGLKFWETYGYKALSAKLRMDSMRDLGPCLSPFNAWLLLQGLETLALRGERHAENTQKLAEWLEAHPSVNWVLYPGLKSHPDYEYTKRVFTNGAGGVLTFGVAGNIEQVRSVVDNLKLCSHLANVGDAKTLIIHPWVTTHQQLPDEEKIKGGVTPDLIRVSVGIEGFEDIKRDFEQAFDKAGLPAATKAGGDPFSKALNLVSGGFMGKSSTGAPRPGTDGTISVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJS7</accession>
    <name>A0AAD8UJS7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha beta hydrolase fold protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_576114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365697.1">
        <property type="nucleotide sequence ID" value="XM_060504893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJS7"/>
    <dbReference type="GeneID" id="85388792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30329" checksum="46ABBB251F58145D" modified="2024-05-29" version="1">MRTLDQVEYSEEATVAAVTDFYAFLTKMYLPESAVVHPPPGGWPTLASDLQGLGKSEEVLSLLSHLPYIRQDLDDSEIPEIAPGGRWIDWRISGTWVREGGSDIDELRTITEGPAITEHVPESVVGLTMSEHHTFLIDTELGVIYWPECPGRLRDGPRCIEDDPYDYCDDEEDAEWRADGAAWSVADFFKVLKAEYRFLRWVPWNEYEVLDSESTMTRNPVPALQDAYQRHGWPNSQEYRKEECLKETKAIMVAIEQGEVEDEGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK59</accession>
    <name>A0AAD8UK59_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endoplasmic reticulum protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_277488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365892.1">
        <property type="nucleotide sequence ID" value="XM_060502109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK59"/>
    <dbReference type="GeneID" id="85386008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="31786" checksum="A75ACC757CDDB4B8" modified="2024-05-29" version="1">MAPPPPANVPLTQRLLLLAQTLQFAWFAGHLSLIFAVIRYGFSYISFNYYSRIARFSYRLTFLSAALTYGIVVYKTLRARSKAGAKAPQSPLALIADENVQYLVMSLVWLLSPQYPLAMLPYAIYSIFHVATYTRANVIPTITPPKPITPAAGASPSGKAQYANNPIADKIGAFVKEYYDASMSVVSSLEILLWVRLLLSAITFQRRSWILIAIYTAFLRARFTQSTHVQNSLALLESRVDSAVGNQGTPPAARQAWETVKGGARQFYAYTDPNRYLSGTAVPKKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKC5</accession>
    <name>A0AAD8UKC5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363183.1">
        <property type="nucleotide sequence ID" value="XM_060510604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKC5"/>
    <dbReference type="GeneID" id="85394503"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="11462" checksum="F9594E965BCEEE97" modified="2024-05-29" version="1">MHFVEPRSGTRLFSAAWFLEPPWSNLQPPATSHERHEPPKAGKTEICQQVAVQSEPQLAGGSCIRALACGLPLRRPLPPPDEPFPSTLRSAPTAAPQTLLSARSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKF5</accession>
    <name>A0AAD8UKF5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DUF221 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_752674</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364487.1">
        <property type="nucleotide sequence ID" value="XM_060514235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKF5"/>
    <dbReference type="GeneID" id="85398133"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF53">
        <property type="entry name" value="DUF221 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="660"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="698"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="12">
        <location>
            <begin position="45"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="13">
        <location>
            <begin position="216"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="10">
        <location>
            <begin position="446"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="11">
        <location>
            <begin position="868"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="968" mass="108545" checksum="D5B4356504136232" modified="2024-05-29" version="1">MVEISLNGDGSDGDGRVGSARDNSTGGGTVSKLNVGSDSSSLMSLVSTLIPVLIYTVVCLLIFWALRRRSLRVYSPRTILRDFFSHEQSVQLPKGWLNWVKPFWTVPDTEILNRSSLDAFLFLRYLRILTMICFVGICITWPTLMTIHATGTGGLSQLDRITIGNVQNSKMLFAHAIIAWVFFGFILFTIYRECIYYINLRHAYLLSPYYSKRLSSRTVMFGCVPPKYQDAARMRKLFGDTVKNVWIPRDTSDLERLVKERDETAMRLEKAEIRLIKMANKRRNKQLKAIAAALPALPETVSSPPSSGSSERSDDPEKGYPHQENTALPDVNGSVAAQWIGASERPYHRPLANFFRRVDTIKWTRLRIKALTHQINKLRRGFLKGEGRRLPTAFVEFSSQADAERAYQTLAHNRPLHMSPRYIGIRPDEVVWSSLRMRWFERIARDFLTRAFITAAIVFWSIPSAIVGTISNIKFLSETFPFLAWITKLPDPVTGIISGLLPALALSFLMAIVPWMLRGCARLAGVPSLSLIELFVQHAYFAFQVVQVFLITTLTSAASAALTQVLKDPLSAKDLLADNLPKSSNFYISYILIQCLAVGAASLLRAFDIFRHHIMAKGFDNPRGLFRIWHRERPVHWGAVFPVFTNMGVIAISYSCIAPVVLGFAAAGLYCIYLVYKYNLLYVSDASIDTRGLVYPRALMHLLVGLYLATICLVGLFALRAAYIPMVLMIGFLIFTALVHISLREAIFPLLYNIPRALALEMEELDGGFVAPDYPQDDFLTDADITAAYPDFFDPGEENEGPTHEVNGTRGVEGASGLMASVQDWSAGAVAKKMQATAEQYGLAGPIGYIMHWIDPAPDPNPNFVLRWLHPGVFDDFSTLRRTIPIDLPDPTETYPADYARRAYWPPEMASPTPVIWIPRDAAGVSKQEVEHCSKVVGCSDEGAELNAKNRIEVELEKAPFWVPRVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKL6</accession>
    <name>A0AAD8UKL6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_731817</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363660.1">
        <property type="nucleotide sequence ID" value="XM_060512877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKL6"/>
    <dbReference type="GeneID" id="85396775"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="12">
        <location>
            <begin position="300"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="792" mass="87911" checksum="0CE422F9F01F7A75" modified="2024-05-29" version="1">MNRRCHDLRQHGNRQLRDCRLGMWGRRDRVRDRCRYPVRERKRPEDGDGVSDEERRRRGSGKLAWGRHHCCLSHLGSGAGGGTKDLCEAEVLPHPEGYVDEERGGKGSCARCGSCTIEPLGHGGGGVGCDDCDCWRDEDCGDGASREVTRQVSPDGTWFVVVVYQTLLSLETSHSYECFGFITDNHLLKDQDEIFVYYFLSLSFIPIKSIRMQIRSVIRSARPVGSLRSGLRPTTAPVALTQRRTKATAPFRLPDPRNEPNPTYTKNSPERAKLEEALKKLRTQLPAKSDLFFDGQTQAAAKSFDTVLPSEHKTKFSNFPLASKEQVSSAIESALEAKESWQNTPFVDRAAIFQKAAELAVTKYRYELIAATMLGQGKNMWQGEIDAAAELADFFRLNCNFAAEILEKQPTRGSDGMWSRLEWRPLEGFVYAISPFNFTAIGGNLISGPALMGNVVVWKPSPSNIYASQILYNILLEAGLPPNVIQFVPGDAEEVTDVVLNHREFAGLNFVGSSDVFRSLYARIGEGIGKKTYREFPRVVGETSGKNFHLIHPTADIEHAVNHTIRGAFEYQGQKCSATSRVYLPESKAEEFISSLKSKVEEITIGSPDGKLDAFMGPVIHERSFNKIKNIIDESNKDSSLKLVVGGTYDGSDGYYVNPTVYVANSPDHRLFNEEIFGPVLAISIYPDAEWSSTLKKVDQSGGGFALTGAVFANDRRAIREAEDALRYSAGNFYINCKTTAALIGQQSFGGARASGTNDKAGSADVMRRFVSPRLIKEEFFPQTEFLYPSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKT7</accession>
    <name>A0AAD8UKT7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363408.1">
        <property type="nucleotide sequence ID" value="XM_060505404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKT7"/>
    <dbReference type="GeneID" id="85389303"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05674">
        <property type="entry name" value="M20_yscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000027">
        <property type="entry name" value="N-fatty-acyl-amino acid synthase/hydrolase PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017141">
        <property type="entry name" value="Pept_M20_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047177">
        <property type="entry name" value="Pept_M20A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45962:SF1">
        <property type="entry name" value="N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037217">
        <property type="entry name" value="Carboxypeptidase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="8">
        <location>
            <begin position="287"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037217-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="573" mass="62912" checksum="EED26CAF9D3F94FA" modified="2024-05-29" version="1">MSEKLPLAHPAPELTAPEPRRRRTAWWSLIPAALLLAYLHKPSASVVPFLGHHRNASPAANACRQVDPLFPTQNSSGLTQLDSYLDSPKFRNETVARLSGAVQIPTESFDNYGPVGADDRWDKLLPFSAYLAKTFPKVHDTLRLERVNTHGLLYTWKGSDDSLKPTVLMAHQDTVPVAPTTIDSWTHPPWSGAYDGTYVWGRGAMDCKNSLIGILESVELLIDAGFSPKRTVVLSFGFDEEVSGERGAGHLAPFLLERYGKDGAAIIVDEGSGFDSQWGQTFAIPGTAEKGYIDVEVIVRTPGGHSSIPPEHTGIGILSELITHIEANLYAPELISGNPYLEKLQCGASYAPDFPDNLRRLLRSKQMCKKKTDRLAKEAAKAGPQVKYLFTTSVATDIIEGGVKINALPERVRAVVNHRVNVGDKTSSVQEKLAAIVRPVAEKYNLTLHAFDDEAETPSSITLKGNDKVLEPAPVTPTSVEGVTPYGILSGTTRALYGEEIVVSPGIMTGNTDTRYYWDLTQHIFRFLPGYDPESDEWAGVHTVDEKTSVKGHVNLVKWYTIFLRNIDEADFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM13</accession>
    <name>A0AAD8UM13_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_782793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362915.1">
        <property type="nucleotide sequence ID" value="XM_060515569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM13"/>
    <dbReference type="GeneID" id="85399467"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF1">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="1">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="600" mass="66542" checksum="9DBA8E161300ACDE" modified="2024-05-29" version="1">MDSLGSRGLSRVLRRTCQDGTTKSSSQTVQSKKFTGGLFGAIREVYNFICTNYVDGDDIIPIGFSRGAFTARSVADMIATVGLLTPMSLDHFYAIFEDYKNMGDSDHDPSLFSDPEVLSYNGEKGAARAKWEGDRKSRYEKWLSKNGLSRHTYGDANGVHEINVKAVGVWDTVGALGIPPAPFSNTQVSDRVENAFHDLSLDEPRFAFRPALWGKLEGNKTNLRQVWFPGNHAGVGGEWHEQQIASITLAFIVGVEFNPGRMADTFTEGLRFSAGQSFSYVPSSWSSWFRPKQQLPWANPKICPVKASSIYRDEAECDGKDRHPAGSAEELWKTARPWGLGQIRYPTSRLQTWSGTTIRHPGTFMRTDPETNQDTGQPLLNTNERIHSLAMDDDGVWDCRALTTADDGSGLWKLERGSGLNASEADSVKDGETRELDLDAEGYVLKPYAVQKEDSQWKWVLASKQPNAFPLAGVLPEEPLTGYWERKLLALTAGNPDVWRWAEENPPLGLIYVLSVSLTGTTGGLAKRGLRRVSDRAETSADLGLSYLTSNGLVQPGETFSRLKPFLRMFLNPTSWEYVSLMAQRFVVSQLKPGNRGDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMA8</accession>
    <name>A0AAD8UMA8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_752483</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364635.1">
        <property type="nucleotide sequence ID" value="XM_060514209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMA8"/>
    <dbReference type="GeneID" id="85398107"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13 20" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="17">
        <location>
            <begin position="39"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="200"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="488"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="19">
        <location>
            <begin position="593"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="14">
        <location>
            <begin position="700"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="1078"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1724580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1225" mass="136659" checksum="B96CEEF071DE2FFD" modified="2024-05-29" version="1">MAPSATSTEWDHQYNTVRRENLFRNPPKDHTAYPALQEAVSPHIDSFNALFTSDDKSLLARGIEDIGTKTYLDGDDRAGLEGKNRLSVRIKSVALQKSQLPPSNKFARNREILPSECRERHSTYRGRLSATFEYRVNGGDPKEFVRELGQVPIMVKSNRCHLEGNSPAQLVQRKEESEELGGYFIVNGIEKIIRLLQVNRRNFPMAINRPSFQNRGQGYTPYGIIVRSVRPDETSQTNVLHYLSDGNMTFRFSWKKNEYLVPVMMVLKALVDTNDRDIFEGLIGLSNTKSAKNSFLTDRVELLLRTYKSYGLYSKTETRAYLGEKFRVVMGVPDTMSNYDVGTEFLRKVVLVHLGNINVTEKQDNDKFKMLLFMIRKLYALVAGDCAVDNPDAVQNQEVLLGGFLYGMIIKERLEEFLSTAVRLSLREWTRKHPATPFTSQDFAKEFPANIFRHANENLGNGLEYFLSTGNLTSPSGLDLQQTAGFTVVAEKLNFLRFISHFRMIHRGAFFAELKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHLAHKCKIMTESVDASKIPGLVAELGAVETSSAATDESVVIMLDGKLIGFCTPRESLRIADTLRFWKVEGTHGVPLQLEIGYVPPSNGGSYPGIYLSSAPARMVRPVKYLPLDKVDFVGPYEQPYMSIAVIENEIVSGESTHVEETPTNMLSILANMTPFSDFNQSPRNMYQCQMGKQTMGTPATALRHRTDNKMYRIQSGQTPVVRSPLHNAYGFDNFPNGFNAVVAVISYTGYDMDDAMILNKSAHERGFGHGTIYKTKKVTLKEEQRTRATKNITKLFGFAPGGFVKGFYRGLLDEDGLPYVGRMVQEGDVLCAWHTVSADYSGKLINLDGQTHYEKYKESETAFVEEVRVLGSESGNEPAQTISIKLRVPRSPVIGDKFSSRHGQKGVASQKWPAVDMPFSESGIQPDIIINPHAFPSRMTIGMFVESLAGKAGALHGLAQDCTPFKFNEENTAGDYFGHQLMKAGYNYHGNEPMYSGITGEELAADIYVGVVYYQRLRHMVNDKYQVRTTGPVVPTTGQPIKGRKRGGGIRVGEMERDALLAHGTAFLLQDRLLNCSDYTRSWICRSCGSFLSVQPTVSPFVGKKKQVTTVRCRNCATRLDAGDAESAAKVEGEIWEDGQGNQWVGGENTTVVVVPGALKFLDVELAAMGVKLKYRIDSKDAPRKGPLKPMKSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMF6</accession>
    <name>A0AAD8UMF6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_652161</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364559.1">
        <property type="nucleotide sequence ID" value="XM_060510506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMF6"/>
    <dbReference type="GeneID" id="85394405"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="232"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="442" mass="51023" checksum="E501BFE1E7149F19" modified="2024-05-29" version="1">MPAKTNGIGIQVEDTKICVVMVGLPARGKSFIAQKAQRYLGWLSIKAKTFNVGSYRRQEDAHPSADFFDFYNTEGERRRRAAAEKAIEDMLAWFRQGGVIGILDATNSTKERRKWVLDICTKEGIEVLFVESKCDNENLIMANIRDVKTTSPDYQGQDPEEAALDFRNRIRNYEKVYKTLDEDGDENEYTYLKIMDVGKQVIINRIQDYLQSRVVYYLMNLHIRPRSIWLSRHGESMYNLDGRIGGDTTLSPRGEQYARKLPELVRDSVGDDRPLTVWTSTLKRTIATARFLPPNYNQLQWKALDELDSGVCDGLTYQEIKDRFPEDFAARDEDKYNYRYRGGESYRDVVIRLEPIIMELERSEDILIVTHQAVLRCIYAYFMNKSQADSPWMNVPLHTLIKLTPRAYGTEEVRYEANIPAVSTWRGKGSTAKHENPIAECT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMM1</accession>
    <name>A0AAD8UMM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_750733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366661.1">
        <property type="nucleotide sequence ID" value="XM_060513954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMM1"/>
    <dbReference type="GeneID" id="85397852"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929678" evidence="2">
        <location>
            <begin position="19"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="457" mass="53232" checksum="78E207A2E458BDFD" modified="2024-05-29" version="1">MPSVKALLVSALVSSTLAAPLITRFENKENAASVFDENPRTSLETRDIETSEDYADLEARDEDEYEYVEATTAAGISARGLEDAEESGDLEARDLKEVSEVYSTFQSRDLEADDDQHGTLESRDNKKSSSSRTSSSRTSSSRGNNNNNRVDKGRVQKEKNEIKDIQADQRKQHDSGRAKEAKERAEIQEARERQKGATNSREKDAARRKKLEEQASLDRVKGQNQRDKNRLQAQKDKEKQELADAKRGGRGGRFVETPETTTNFNPKSYDGKSGTYNDYKNPNYQNKDSNYYSNQRNKDDERIRQLERDRAREDSRINKAEYNKNKSGDKIKNGEYNKDKEDEAIRKAQYEKQRSGERIQDAERAKDRYGNNGYNKNNYDREIRAEEARRQRADQQIRESQYDKNKQDQLIKAEEDRRTRYDEQIRKAQNDKNKYGDRIQDYEQQRREDERRRNGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMT3</accession>
    <name>A0AAD8UMT3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_615235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366766.1">
        <property type="nucleotide sequence ID" value="XM_060507885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMT3"/>
    <dbReference type="GeneID" id="85391784"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="226"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="303" mass="33506" checksum="42B1E5272CEA5A89" modified="2024-05-29" version="1">MLMPSAFSCDTSQPPLTRLQASLFASPPSSPPTLSTTSGFGHILDSCRSLQALLSSPQHQNIPSAALSYDAPQQYLPTPSQLPTPPLAHAPAPHKLRLRSRAKQDGAINNEHLPRKRIAKRAPPRGLNKRRRAADEEMGREDGLLTDEDVESDLDISSQRQSFEANNDTLIPSNPSTPKRARIAPEVIPLGLERSDYHTLHLLNGDGVNMNHGSMEAAGTQDSNVEVEADGERWSAEDDRILVELVLEKLKLSKTEWQDCARSLGKDRNCLSRRWKSLMVQGDVGLKGPRRSSRRANLHGTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMV5</accession>
    <name>A0AAD8UMV5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_752535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the methylcitrate cycle that catalyzes the synthesis of (2S,3S)-2-methylcitrate from propionyl-CoA and oxaloacetate. Plays an important role in detoxification of propionyl-CoA, an inhibitor of both primary and secondary metabolism. Also has citrate synthase activity using as substrates acetyl-CoA and oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364518.1">
        <property type="nucleotide sequence ID" value="XM_060514215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMV5"/>
    <dbReference type="GeneID" id="85398113"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050440">
        <property type="term" value="F:2-methylcitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="469" mass="51804" checksum="D0A89D3DB4AB69E5" modified="2024-05-29" version="1">MSVARLSTSALRTSLRASPFKVSAFNAARCYSSKNQTLKERFAELLPEKIEEVKALRKEHGSKVIDKVTLDQVYGGARGIKCLVWEGSVLDAEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPTEQQVRDLSAEWAARSDIPKFVEELIDHCPTDLHPMAQFSLAVTALEHTSSFAKAYAKGVNKKDYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGKVAAVEKDKDYSFNFANQLGFGSNTDFVELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSVAAGLNGLAGPLHGLANQEVLNWLTEMKKSVGDDLSDKAITDYLWSTLNAGRVVPGYGHAVLRKTDPRYSAQRKFAQEKMPNDPMFQLVSQVYKIAPEVLTQHGKTKNPYPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIGVLPQLIIDRALGAPIERPKSFSTAKWAELVKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN88</accession>
    <name>A0AAD8UN88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_280388</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365987.1">
        <property type="nucleotide sequence ID" value="XM_060502128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN88"/>
    <dbReference type="GeneID" id="85386027"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore-iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000197">
        <property type="entry name" value="Siderophore iron transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="611" mass="66381" checksum="95E5B8B0E5FEDFAF" modified="2024-05-29" version="1">MGLFGRKKETESPSDIVSPTADVTPTEKNAPLSQNTPPPPGYESNNIFGEKSPGVARIEALSAAITTTDRYFIFFGVFLVAYAYGLDGTLRYAYQPTATSSYATHSLLATVNVLRSVIAAAAQPTSAKIADVFGRVELICVSVVFYVVGTIVEACATEVKAFAAGAVVYQVGYTMIMLLVEVIIADITSTRARLLFSYIPALPFIINTWVSGNISALVLGESTWQWGIGMWCIIYPVCALPLIISLSIVGRRARKQGLLDSYSSPFRMLGPKKFLIELFWQLDVIGIILVIAIFALILVPLTIAGGFSTTWREAHVIAPLVVGILCIPVFAVWEMKAKHPLVPFMLMRDRGILAPLGIALGLNWAWYMQGDYLYTVCIVAFDFSIASATRITSLYSFCSVITGFILGFIVFKVRRLKYFIIAGTMLFMVAFGLLIHYRGSPTSAGQSGVIGAQVLLGIAGGMFPYPAQASLQTTLKHEHLAIMTGLYLSTYNIGSAFGNTVSGAIWTQVLPSVLQENLAPFGNDSLATVTYAQPFVAIAEYPVGTPERAAIIDSYQHVQRLLTITGICLTVPLIAFAFLLRNPKLNDQQTLAVDDVQIRPAENNDNLPSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNS5</accession>
    <name>A0AAD8UNS5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lea domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_577582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365013.1">
        <property type="nucleotide sequence ID" value="XM_060505033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNS5"/>
    <dbReference type="GeneID" id="85388932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022124">
        <property type="entry name" value="DUF3659"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12396">
        <property type="entry name" value="DUF3659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="364" mass="38751" checksum="1623DEE4A230D67A" modified="2024-05-29" version="1">MHHTEPRPAAGAGDHDPTSRHDEYEVVEVEDGQAGAEEAPKATFSRPPLPRLNSQSRAASSPAPFHETNPPQYPHRQVSYTTTPQPEQGGPVHLQGSREIPIPMRPSSTQYQTGPEASTPPTTETTDNGTDEGSQDAKSSSQGTTPKPREKNAPIAIPKVTPLSSDLRLPPNLAELAQGLDGKYVDEFGNILDWNGQVLGRVEGDLPSMIGRPVSVTGEIFSEDGEVVGYVAENDTIPPTPPSPKPIEGMGDGLKVDHMGNILDKNNNVVGHFDGAPLAKSVQQTGQPSSSGQSSNPRPGYMPDTHTSCPQCTAHRQSKPSADTPSPSEIFMDVKSTNDGIQLIIKIPTVFQGGGNPNIHIGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP79</accession>
    <name>A0AAD8UP79_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_620768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365268.1">
        <property type="nucleotide sequence ID" value="XM_060508214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP79"/>
    <dbReference type="GeneID" id="85392113"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="89" mass="9613" checksum="38C1CF154662ADE1" modified="2024-05-29" version="1">MLSLRQQLNMLFPSSLIGSSRAYPAGDPSRANKHTYGASHSSLSFLARTAFLDCMLQVVTVRNAGPGWAEKATALPLTSILIVPPQQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPT5</accession>
    <name>A0AAD8UPT5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7871 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365044.1">
        <property type="nucleotide sequence ID" value="XM_060514156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPT5"/>
    <dbReference type="GeneID" id="85398054"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057193">
        <property type="entry name" value="DUF7871"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40620:SF1">
        <property type="entry name" value="RESISTANCE PROTEIN CRD2, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04318)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25277">
        <property type="entry name" value="DUF7871"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7871" evidence="1">
        <location>
            <begin position="5"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="11432" checksum="AAD3E5CDA205294B" modified="2024-05-29" version="1">MTVTKASTCCGKSAECVCAQQATCSCGKQSALHCTCSKAASENAVAGPRCSCRARPVGECTCDRAATENTKPSGETCSCGSRPADACTCDKAATTTYDRSEHEIDFTTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPV8</accession>
    <name>A0AAD8UPV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_615195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366752.1">
        <property type="nucleotide sequence ID" value="XM_060507883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPV8"/>
    <dbReference type="GeneID" id="85391782"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="11689" checksum="48971406484EA6E9" modified="2024-05-29" version="1">MRMPCLDAFNGTSEIERDTREEPDPVMLVRNSLSFSVQGSACRVYESHLLSKLSFSSPLRTVVRIGLSHNSDSWISTTAGSSVAFPQGKARKASTAISPLGLFGLQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ23</accession>
    <name>A0AAD8UQ23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_575785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365879.1">
        <property type="nucleotide sequence ID" value="XM_060504853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ23"/>
    <dbReference type="GeneID" id="85388752"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="8">
        <location>
            <begin position="69"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="333" mass="37677" checksum="9885CADD7E10D8E2" modified="2024-05-29" version="1">MKDPFFLEPLPWLVKATQPFADYFSLPTLPIHVHEVLASALLYSVIYYPVSPLLSRLIVGRKYLDLPRKRRINWDAHVVSLVQSLLINGLALWVMFVDEERSTMDWQARMWGYTGAAGMIQGLAAGYFLWDLVVTSLNMDVFGLGTLAHAISALFVFSLGFRPFLNYYGCIFILWELSTPFLNIHWFFDKLGMTGSRAQLYNGLMLLFTFFSCRLIYGTYQSVKVFSDIYAAINAHPVLPKEISPETGAVLAPTGVMRFATASSTVPTWLAVTYLMSNITLNSLNFYWFIMMIRAVRKRFQPAKSTDKQATIEPSTAKATAASPTTQARRRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ26</accession>
    <name>A0AAD8UQ26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_791422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366270.1">
        <property type="nucleotide sequence ID" value="XM_060515733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ26"/>
    <dbReference type="GeneID" id="85399631"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="39591" checksum="5D01829B3890DCB9" modified="2024-05-29" version="1">MASIVNNEVQLVAEDHVNVTDREADIESIQSETTSIKASMLEWRQENGRTYHKYKDGKYLVPNDETELDRLDMQHEIFYLTWDGKLGVTPPCEPGAKVGRVLDLGTGTGLWVIDFADLHPEAEVLGMDLSPVQPSDVPPNVRFEINDIEEEWLYSRPFDYIHSRIITGGISDWKKMIKKAYDHLTPGGWYEIQESDMSPAADDGTLPPEKALSKFGALIREAYVVMGVPLVHVPDLKDVLTEVGFEEVELTVFKWPTNPWAKDPKYKKIGAWNYHNFGGAVETVSLAPLTRVHGWTKKEVLVFADEVRKDLRDPKVHSYFPIYTLVGRKPLEAATKPTATEAAPAEASTSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ85</accession>
    <name>A0AAD8UQ85_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_615063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366932.1">
        <property type="nucleotide sequence ID" value="XM_060507879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ85"/>
    <dbReference type="GeneID" id="85391778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="28792" checksum="B1E20D1ADAE40640" modified="2024-05-29" version="1">MEAQRPRPPNPSELCSCILHWHELGPDPPGQYGTYRLPDLVANTIENGQALGPYTNLEHHDELKHALIEGFHELYNNQDPSHYAQIIRVASLLDHYFFRGWLTARRRRTGIVQSHLKVCIRENNEVCQDQGSASHVEVVKEQVGSLPSVDIDIDSAGTWTIAQIVELLIHEMTHGYLILFTCRGGFDYMAGCSFHHSAARGHHGLYLRKLLRHVYQTIQEWDDMLSNFGTDCVLSCPCNDSDSAFERSRSSTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQC3</accession>
    <name>A0AAD8UQC3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Squalene/phytoene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_616435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366420.1">
        <property type="nucleotide sequence ID" value="XM_060507975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQC3"/>
    <dbReference type="GeneID" id="85391874"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="366" mass="40939" checksum="1C3D27BD17D6EA89" modified="2024-05-29" version="1">MNRTTRIAGHGLRRPVQTPPRSTRGIVTDADVVKARKYCQSQLQHSDYDAHIISRLVPARATDTYLALRSLNLELVRLPELVSNPTIGQMRMQFWRDSIDKTFAGAPPAEPICVLLHQALQDLRARSPGNATASSIKFWVQRLVKTRAKHMDNRPYASLAALEEYAENTYSTLMYATLASMPLRSMQVDHLASHIGKACGIVAVLRGIPVLAAPQQQPAKSHAGPGGGRQDPALLLPLDVMAEVNLREEDVFRYGPQAEGFQDAVFKVATRANDHLITAREMLKNLKAGQDAGHEFEHQGEAEHVYEPEEDDTQRDLRRGFGVLLEAVPAQEYLTNLEGTNFDPWTVKPSWKLPWRLWRATSKSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URT5</accession>
    <name>A0AAD8URT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BSD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366049.1">
        <property type="nucleotide sequence ID" value="XM_060504789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URT5"/>
    <dbReference type="GeneID" id="85388688"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="241"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="46498" checksum="2D694A36ED7B0347" modified="2024-05-29" version="1">MDLAYDHIQENSLPKDADKKNGDAKETKSDQPQSSLNDDLQEAYKAISSSPWGMRIGGFLGSAVKQGQEVYKEASKEVTELGQDASKGFSSIINRTRSLTVNTTQDESSGDKSKETDSQTTPTKTRDLAASDDAMSSSENYLTRLRSEAAKRLKDLQKAEDAADEALLRFGTNISNFLKEAVSIAPPTDANNQGGAVMFESKDAQGKRVIHTSRQDAQLHVIHTSTESFAKDPATEEFATWAKTFDAEKKTAEISDDLNKYPELRTTMEKLVPDQVPYAEFWKRYYFLRHGLEAAETRRRDLLKAASAEDEVGWDDDSDDEATTTTAPAPASATAATAATPASAAGAAPKTEKTQARPPSAESSTTIQPPAQTSSTLKPAESRKSNDEKSQADSDTSYDVVGATSGVPSQAPNSPKDSRKADDSDDDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US93</accession>
    <name>A0AAD8US93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_179102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367922.1">
        <property type="nucleotide sequence ID" value="XM_060501514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US93"/>
    <dbReference type="GeneID" id="85385413"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="113" mass="12604" checksum="804BDC6AF7B6909F" modified="2024-05-29" version="1">MDETRLPHPPPFLPKKGARSRSGFPRRMSTKAGVAERHGRIVQLNMIILHKELVVCHFSLDSTISTAVGRRRSALSSPRTIPRSYKIPGVLVLLHRTHALPVYAKSSRTPAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USG5</accession>
    <name>A0AAD8USG5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_608844</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368728.1">
        <property type="nucleotide sequence ID" value="XM_060507498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USG5"/>
    <dbReference type="GeneID" id="85391397"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="459"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="521"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="560" mass="59703" checksum="FBA3836D3E8F5FCF" modified="2024-05-29" version="1">MCAYRVELQAIVHSHSQKNLIQPHPTQHLDPFRPNPREYTHQQITMDPPKPSPSASSTTPLEKPSFPAITPLPKAPRTFQTPTKRINTGTDLATFLTTTAYRDILLFLLQLNRSLCPRRNPTRPTGPSTTYTLSSVPSTPERGLPPSIARLQALLAEAEALIDLAPPDPGPRRFGNVSFRKWHELLAERAPALLSKHIPNSVLAFPATPSSEPPAAELLAYLLGSFGSAQRLDYGTGHELAFLAFLGSLYKLSYFADDTTTAAASENGKPNPAAAAPDTSALDRTIVLGVIEPYLRVIRRLILTYTLEPAGSHGVWGLDDHSFLPYIFGSAQLAAPVSADSDPMPTEGSVRGAPKTGDIVKPAVVEDQRSENMYFSAVGFINDVKKGPFWEHSPILFDVSGVKDGWGKINKGMLKMFNAEVLQKFPVVQHFTFGSLFSWDQDPNAAPVSQSVHAANQPSYNYPATTAPPPPQAGAGTAAPWATAGGAGAGAGAVPMGRMPPPPPGGAGISYSRQPPPPPSSAASARGPPPGMMAMPPGAQQARQGTADAQIALTKAPWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT69</accession>
    <name>A0AAD8UT69_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_773087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366936.1">
        <property type="nucleotide sequence ID" value="XM_060515400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT69"/>
    <dbReference type="GeneID" id="85399298"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="31329" checksum="276F1AEC2DDF32BC" modified="2024-05-29" version="1">MEHSMPVDQGTRNLVSEETQNTSHQCQEVEKCHHPPFPKPSPQILLLTTSRDLPPYLPLFVGMYAATPLLNLTCRNFYRCKLRPQQEVAQREFVQLVLNALAVSKAWYDLDPEELEAFEKSRYSRTEVESLALQLEGSLHEMMVRLDDFFFFGALTRYPHNPTDTNVPRYSHVELLTGFGDLKGKGEGNSLADSTPVFEVGRWFAKIRLFPKTTVNKNLISKVERISFEEIVASLIHEMQIDPDAEFVDDEDDGDYDDDEEYENDGDDDMSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT81</accession>
    <name>A0AAD8UT81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_749566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368085.1">
        <property type="nucleotide sequence ID" value="XM_060513779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT81"/>
    <dbReference type="GeneID" id="85397677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04396">
        <property type="entry name" value="RhoGAP_fSAC7_BAG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051025">
        <property type="entry name" value="RhoGAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228:SF25">
        <property type="entry name" value="F-BAR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228">
        <property type="entry name" value="SPERMATHECAL PHYSIOLOGY VARIANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="183"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="652"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="668"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="790"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="813"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="832"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="869"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="898"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="913"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="955" mass="101985" checksum="4E973AE0104BE52C" modified="2024-05-29" version="1">MTSAAPPPNQAFQPTSNSTAPAAPSTPNKRDLKSWWKGFKLPSKHQEHHGRAPSTFASQQPPPTPTQPLFSEDVDEAIDTSAVPLSLVLLLQDAHSVGSCDPILPQVCASSDATASNTLNPTARLNRLSLSITMPVRQCAKHIRAAVKTSSTSCAKGSTADNRPHGIFGVPLRQSITYANVAISLVDENGKSYIYGYVPIVVAKCGVFLKEKATTVEGIFRLSGSEKRIKELKQIFDSPDRYGKGLVWDNYTVHDAANVLRRYLNDLPEPVVPLDLYEKFREPLRGATRQAVGDAEGPQFVENFDDQAAIVKYQKLITELPPLNRQLLLYILDLLAVFAAKSEENRMNSQNLAAIFQPGMLSHPQHAMAPEEYRLNQCVLIFLIENQDHFLIGMQGTATDEKTKQLIEKGTPPAASGPVTPNPNRKSGLGRSASNASAGADSVRRDGMLRRNRSTSSRHSHHEGSTTPNSPALAPTPNSGLGRSNTVPSKKSPALQTGRFRRDASPIPGSSTREPMIPTTTEELVEAPDQSPAASSISPAPAAIGTSSLAPTAAGNAGRSQERLLDPNEATTPIKERVLPGIFQRSPTGEGEKRQPNKLKKKRIPGSLNPSAQSSAASLSGTHSAAVSPSFEAPNPMDLVADTIPEHDSLAVGQQPGAVDTPSEPTPRASQVPSSNTLHPEQTLKAKKSPPTSLHSSFNEGSDVDQTEESIVTTSADASEPDKEKKRRWRLSRQRGHEHHPSITSPRLAFGSNDNADVSVTSIGSGGYRPRKSFTGESSDTGMYTAEAQTSHESRDKDGKDESKGPIGWIRNKYREAKENAERRNKSPPADRQSSLGGSSIMSGRGKSLDIRREPEERAPNPPVPPLPQQAAPIQTAAAQPAATQTATSQPPPPQPTSAPAQQASSPTVTSPVSPPPASTVANPPAPAQPAKSQLAAASQPEIAPPTQPAPEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTF8</accession>
    <name>A0AAD8UTF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_152344</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368220.1">
        <property type="nucleotide sequence ID" value="XM_060501335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTF8"/>
    <dbReference type="GeneID" id="85385234"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="38055" checksum="2421B2CF2FE5AD64" modified="2024-05-29" version="1">MHHCRPDDDNDFTLSLASASFQTGSESLEITSFGLVKQIVAAQRQTCAECSEYCSSESALEYHAVNERHKAYACLQPGCGQRFVYRILYDQHHREHIDGHKRVDEEHPLVCVECLVEFKSMAKLQEHGYDAQHSPFACSCGRNFARLDVLNRHLDSLGTDLPKFPCQFCKNHRGKNGFRRRDHLLQHVRGYHKFEAEEKIDGIMPNHRGKYQTPPVCHFVDCLHHRDDIFETLSREEQNRSKPFESQSEYTKHMKNAHDFTQYPCTVRGCSKTGAKGYAREKDLIKHRKKDHPEAGTYVPASRDTKITCLMCTRRVPNNGYWHRCRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTH1</accession>
    <name>A0AAD8UTH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_613987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367086.1">
        <property type="nucleotide sequence ID" value="XM_060507794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTH1"/>
    <dbReference type="GeneID" id="85391693"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="47"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="410" mass="45375" checksum="CB8475C018E3EB2E" modified="2024-05-29" version="1">MMDPAQLPAWDLPRGVASRYVDTSPVGLKFHILESFPVDDPSGSPPPLIILLHGFPNLSFDWCAVMPKLAAAGYYAVAPDMRGFGRTHNANLRPIGEETVRPLTALRDVVTLVHALGYETIHTLVGHDLGAFVASMCAITRPDMIKSLVLMAHPFKGSPQLPFGTGVAPRLASVLRPKQEDSGKTAKVDNDIQSSLLKLEPPRKHYKYYNASSGAVDEWTHPTGQPMHDFLRGYFHLKSADYSLNKPRPLESWTAQEISVMPHYYVMKADLSMRENIELDMAQESADVRAKLSETPWLTDAELQVYVDEYSRNTFRLSLLWYRVLIDPALSADLLCFAGTKLAIPTKYVSGTHDWGTYQVPGALEAMESGESVRSDCWRGSVIIPGAGHWVNIEKSEETAQEILALAGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTP1</accession>
    <name>A0AAD8UTP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_272341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366185.1">
        <property type="nucleotide sequence ID" value="XM_060502067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTP1"/>
    <dbReference type="GeneID" id="85385966"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="30581" checksum="4510B39F06346CC7" modified="2024-05-29" version="1">MAAAACHGPSTSTSHVKVGCYQETHHLDPEYPTPYCPRVFCEYHAILPRILKPLVVNTRVSRGNSRQVFEYAKPQSATNYTINRPCLKRSCTRKVSKTSLERAFTTPNTQLSADTTGNVQSRRIPIGLVLHTLGRLGMSLAARNTPHPTNRVHREKSIPQGETKPRNLTSYSSQSPPPLSLDRSYDHCLTHRTTTPLHKTSTSMHPKTGIPIFNRPQKFCFFSTATASSLSTHIYNPDFAVESYFSSPKRWFPIRSPKRSGICIRSQMRQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTY7</accession>
    <name>A0AAD8UTY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_611805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367773.1">
        <property type="nucleotide sequence ID" value="XM_060507683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTY7"/>
    <dbReference type="GeneID" id="85391582"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="55" mass="6011" checksum="F8530D3A1C19DC28" modified="2024-05-29" version="1">MVPAGRRHLDDHPVSHPPKGPRIHDQTLIRCHPATIRAFIYPLSPIPLTSTAGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU34</accession>
    <name>A0AAD8UU34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_717591</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367799.1">
        <property type="nucleotide sequence ID" value="XM_060511964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU34"/>
    <dbReference type="GeneID" id="85395862"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF12">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="42321" checksum="63B530A98CE79D57" modified="2024-05-29" version="1">MPPIRLATASPATAATTSQTLSDISTLASRASTSGADLLLLPEAYLGAGYPRGASFGSKIGSRAPEGRDEFLAYFNAAVDLGDTVGDAGAGGGDKWVKKQLPAQHAGAKVERGDGSREELEKIAAQTGVFLVVGCIERAGGSLYCSVVYVCPKLGMIGKRRKVMPTATERLIWAQGSPSTLRAVSTTIKGVRINLAAAICWESYMPLLRQSLYAQNINLYLAPTADGRDTWLPLMRTVACEGRCFVVSSNMAARPLTVASSSAATTTAAAVDNDSGIEDAPDAQIYPTRARRNSCLTEDGNEIAPPGTSNGTNKTTKVTTSSKPALESKDWVSRGGSSIVGPFGDVLAGPQWEDDEGIIYADVDFEDCIRGRLDIDVGGSYSRNDSFKFSVEGLDLDPLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU83</accession>
    <name>A0AAD8UU83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_115213</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368685.1">
        <property type="nucleotide sequence ID" value="XM_060501121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU83"/>
    <dbReference type="GeneID" id="85385020"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF187">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="552" mass="62632" checksum="AF14878AF16658C9" modified="2024-05-29" version="1">MSVLLDPSYQAVLVYGLGLLCGVAVHLGIFIHGEWHVQAPQIALGHFWLFSCFAALSRYYKGSVVGDLCHSLLILSAGYLPGLFTSIILYRFYFHRLSSAGFKGPWYARVTKLWHVWACRDCKNHLLLENLHEQYGDFVRTGPSEITVFHPGVFMAVDGPRSECIKSEWYDILHPDRALVTTRIKPIHAARRREWNRGFSAQALVQHESKILKYIEQLDVCIEADAKAHVASEVRNLFFWFGFDVMGDFVFSKSFDMLHQQQWHHIIVRLQRALSLLGPFSPAPWLIQVGFKLGPRISVLKDWFDMVAWCERQMRVRLDDGTPKPAVPDLAYYLMELNDGQTELKDRLPWLYGDSLLAIVAGSEPTAAALIGIFCELAKHPEHAEKVYEELLDVDTTNIKTLTSLPHLNAVINEGLRLYPALLTGGARKTTENGATIGGTFIPPDTTIIAPRHVISRREDCFERANEFIPERWSTRPEMIHNVAAFAPFGTGHHSCLGRFLATDTMRFVVARLVKKYHFRLAPGETGNRVFDDVRDQFTSNPGPLSLCFELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUD1</accession>
    <name>A0AAD8UUD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_607805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368760.1">
        <property type="nucleotide sequence ID" value="XM_060507452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUD1"/>
    <dbReference type="GeneID" id="85391351"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="12144" checksum="75BCA5277A2A5EE8" modified="2024-05-29" version="1">MVNIPKTRMTYCKGKECRKHTQHKVTQYKAGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECIKCKTKLQLALKRCKHFELGGDKKTKGAALVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV99</accession>
    <name>A0AAD8UV99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxymethylenebutenolidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_749482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367986.1">
        <property type="nucleotide sequence ID" value="XM_060513772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV99"/>
    <dbReference type="GeneID" id="85397670"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="384" mass="41985" checksum="FA4A10956E47DA32" modified="2024-05-29" version="1">MSAVTIQPPLSRRGHGPGLIIVVEEGINLSKHDKILDPPPSQKWAEEGYAVAQIIVAPGAADVAGQITSAIQSLRELDSCSGKDKFGVISLINAPSPQLVDALESHSEIKAAVFYNFGQALSIPTLSHLPKTQTDGPKPTPAAKTHAYPGASDFFVVPSHPNFNANAAGLAHTRTLTFLKPLLGGPYFDLEAVWEEHTLFEFGERNVEKTMATMVDQPYVNHVPTLTGGVGRQYLTSFYRDHFIFNNPDDTELELVSRTVGIDRVIDEFVFKCTHNRVIDWLLPGVPPTGKHLSIPFTSVVNVRGDHLHHEHIAWDQATALRQLGLLPEFLPFPYQINGSGPTSGKKFEFKLPVAGVESAHKLVDESAVESNAMFEYGTREVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UX59</accession>
    <name>A0AAD8UX59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_717376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368045.1">
        <property type="nucleotide sequence ID" value="XM_060511942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UX59"/>
    <dbReference type="GeneID" id="85395840"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="30"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="3">
        <location>
            <begin position="239"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="41810" checksum="059A1A076B3A6D41" modified="2024-05-29" version="1">MKHIADNKDTKECLKAWAGTRKLLVCTPIQRSLEGLFRSLLFGVLAKKPALIPKIIPDGWGTSPTAPRQSEFETFLRLLGVHLDELSCKIIFFIDGLDEFEGDHIDVCETLKELSRSPSMKICVSSRPWNVFEDALGEKSDSKLYMHELTYNDILDYIANRLQAHPRWKVLLEEVNFVSSMSLIEEVAYKSNGVFLWVTLVVRLLREGLTNDDSLSDLQRRLETFPEDLQVFFRHIIKSVDPFYNEKMAGTLSLAMQARGPLRTEIFSLHDFEYGNENYAFKDIADTKLMPTNPKVLEKIYRSVSRRINGRCKGLLGRNGNRMEFLHRTVYDFLRTGEMDDFLREHTKNSHCFSLSLVKAFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7Y4</accession>
    <name>A0AAD8X7Y4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vegetative cell wall protein gp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_199456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000231">
        <property type="protein sequence ID" value="KAK1706111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357759.1">
        <property type="nucleotide sequence ID" value="XM_060501648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7Y4"/>
    <dbReference type="GeneID" id="85385547"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37242" checksum="F2432C9B12117113" modified="2024-05-29" version="1">MAYSSPYTGSTPEEYYYARERFQSATPTPSPRGSSSYYYPPGSTPQRPATRSHFRTPSSGFSEYSPRPPTASPRYTSDGYYATANSGFAYIERDIPAYEPRPSRTPANSHSRRSSTSVPQRPSTVRPGSSSQASKKAQPQTETKKPQPPPVSRAATEQDAKRHKIPSGYSLKNWDPTEEPILLLGSVFDSNSLGKWIYDWTVYHHGPATPIADMAGELWLLLIQLAGKLKRGEETIERVRSTEKKEILDDFIDAGERLTDKLRKLLKTCEAPMLKASKKSSSLGKNAGVQFVETLFGIERELDKTERFMQGVRLFILRFDANCDDILKNPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X909</accession>
    <name>A0AAD8X909_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_767331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358567.1">
        <property type="nucleotide sequence ID" value="XM_060515281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X909"/>
    <dbReference type="GeneID" id="85399179"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="457" mass="51779" checksum="9A8E7306379ACE14" modified="2024-05-29" version="1">MARKGSRKTRTGCITCKIRKVKCDETKPTCNRCAATGRQCDGYSPAPSPTNKSQLRRYRPHHVFPGADGVGEGRALQFFCEVAGPYMSGAVDPHFWPKLVMQFTSFEPAARHSVIAISTLCERLQFQEDMDEEILLKDDLYALQHYNTAIHDLRTMTSPERSPVILLVCLLFITVEFLQVNRDETVKHLKHGFQLLKSTIRDYAWTKEHLLPLFRRLSIYAFLHATDPRDFPDLEGLEHQIPSSFSTFYDAQRMVDDIFSRTMRLVRNGDPYRIYPEEHQFVPPDLLVEQASLASSLDQWKILFDAFEARPASPPSESVPGQETLTTALRYVIVSRYECCRIWLNTAFGDKEYDYDSHLAVFKAMSTEAGIVDPEVLATFEGSPYFTFDTGYLPSISLIATRCAHLEATLKSLRLKPLPGLPRENMCLLAQAGDCLCEALPASSRNLSRLEIAESTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X958</accession>
    <name>A0AAD8X958_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_591635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358717.1">
        <property type="nucleotide sequence ID" value="XM_060506456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X958"/>
    <dbReference type="GeneID" id="85390355"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019180">
        <property type="entry name" value="Oxidoreductase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039251">
        <property type="entry name" value="OXLD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21193:SF3">
        <property type="entry name" value="OXIDOREDUCTASE-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09791">
        <property type="entry name" value="Oxidored-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase-like" evidence="2">
        <location>
            <begin position="150"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="28860" checksum="704AFBE29851E923" modified="2024-05-29" version="1">MSAPARFLPRLRPLVPRIARVPRGAFITSQSQTGPAPIEPSQTQAHPLGAYYDAILNDPQPIPDVKPEEPPNSSVHKQEQGRKTSPPSPSPSPNPTQTTEPVAEALSAQPVPTPPPQTAAEKAAIVFGSALAGPAARQKRLEELRSKSTTIAGVTIPPRPEEPDNCCMSGCVNCVWERYREEMEDWSAANAEAQLKLKEQQGAVDSNTMDDDGGGSDTNWVPQDPKIAKNMWDEKLYDDVPVGIREFMKTEKKLKAVHEKEGTTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9L2</accession>
    <name>A0AAD8X9L2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_108934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000155">
        <property type="protein sequence ID" value="KAK1711888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359212.1">
        <property type="nucleotide sequence ID" value="XM_060501075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9L2"/>
    <dbReference type="GeneID" id="85384974"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="77490" checksum="E09101A388AAFC7A" modified="2024-05-29" version="1">MRPNKAPRWGAVSRTSDKASILTLLGISELLKLRGKWRMALRLGTFALRQSQGLGTLTEGLALLSVGHAYRNQTPEDWISAQHHLRMAKLLLEGLPTSEDQIFYLMRAVLLLGDTLVRREDLGDIAEAEELAHLAERLLRQSREGRSSDSGSSSKGRSFRWTLFTGSWRDFCLHSMVELGEIYYYTSRWAEGEKLLRELVPTLVRRRGKRHVTTIEAQRDLASMLVNQDKYEEAEIAYRIARDWNEEVPVFGHEEKAAIDYNIAMCLSERGRDEEARVEIGNMDLAADLLHYANGEWTLKLARLTSLRLKKYDEVIGLCRRFQRVLDEHRARFGVCSTVTLRNMEDHVTALKALRRWDEAIVILRDMCRREASDVARVVEQTLETRLNLAHTLRCAGLHEEAAYEYRKCLEIERAASNDFQDEAQIRNILKYLAYLYELAGDKTNALIAYSQLQREYWGRPSHHRNFIKYEWCRGKMFMLQGRWEHALKLLLGALAVKRGIETAVSIITGLPIEAVHAMQPGRRVPEPTQQDISEVDDETDEEEQDLKGLEKVDTRGQVQVQELDGPDTSDDEAEQQSWDEIDWWEEVIKDAVDAVRREEPFQACTPLDEADSEVDDDDVEETVDAVLTLKSGYPAVPAGDEWSQPQWPRLPDTYEELVIQQRSVVEESRPWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAH7</accession>
    <name>A0AAD8XAH7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000260">
        <property type="protein sequence ID" value="KAK1704658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357459.1">
        <property type="nucleotide sequence ID" value="XM_060511022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAH7"/>
    <dbReference type="GeneID" id="85394921"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="308" mass="33862" checksum="6E224328FC13B6E5" modified="2024-05-29" version="1">MAYLPSLSLNARVVIVVPLCLTNLLALEKEEDRFLLRRLGRGREHCPRRRRILLDLVVDPGFVGIRHLRDLLAGLPYFGFVRYPSHHPIPSSHSIIPPHLPFFTNLSQSSTTSSPPPARSPSGPSARPRSSSPPVPSWVFTSSSSFTQPAAWCPFGGIPTVYSDEDIGSPEAPLPAERWLCRPCPTPTIPGTGSTWGSDPTSAFAAPVTPIWKVGRALGRCWTGCTTARRTRGWTWGASRSLTTIVGGCGVRSPWRLRSHTCSLWVGLWSSTFTLWGFSASHWRPLEPGGRCPQLSWLPEPFPSFFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAL6</accession>
    <name>A0AAD8XAL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360247.1">
        <property type="nucleotide sequence ID" value="XM_060509206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAL6"/>
    <dbReference type="GeneID" id="85393105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="54"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="252" mass="28501" checksum="14AC4714FFDF37DE" modified="2024-05-29" version="1">MGPFSTLKDAEPEGSGPQEFAYALRCVQLLAGHGSQPISCKLKPSTLGRIPYQYEALSYAWGDTTKRVEILLEGQPFKITQNLETALHRLRSAKEDRLLWIDAVCINQQDRSEVNLQVKRMWAVYRYASKVIVFLGEGTANTHHAIDLIQTLAKEKKGLSHRYVTSLLFTKDAQPTKQALRTLMSSPWWSRTWVIQEFSVATEVAFVCGNLEWSGESFSEALRTLVDVRFNASLPRGQELKVVPCEVDKRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAX9</accession>
    <name>A0AAD8XAX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_798173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000279">
        <property type="protein sequence ID" value="KAK1703560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357311.1">
        <property type="nucleotide sequence ID" value="XM_060515919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAX9"/>
    <dbReference type="GeneID" id="85399817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1703560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="481" mass="52478" checksum="763D97472241E9BB" modified="2024-05-29" version="1">MTTNGTSKLDWTKFYNIIDGKLESTSKTRNSPNPSTLEANPEVPLSTPEDVDRAVQAAKKAQDAWSETPYEERQQALFKLGEALEAHADEFALMLTKEQGKPLPFAQFEIGEAVKHFKGMTNLPFPEEVVDNNPDRRVLTRYVPLGVAVGIVPWNFPILLACGKIAPALVTGNAFILKPSPFTPYCDLKLVELAQQFFPPGIFQALSGDDNLGPWLTSHPGVDKVSFTGSTATGKRVMESCSKTLKRVTLELGGNDAAIVLPDVDVKAVAPKIAMLALYNSGQVCIAIKRIYIHEAIYDELVAEIATAIKNLPVGDGQQEGTMLGPVQNQMQFERVKELLKDIEETKLKVAAGSTAPASNGKGYFITPTMIDNPPDNSRIVVEEPFGPVFPVLKWSDEKEVIHRANDTLMGLGASVWSKDVEKAQSVAKKLKAGNVWINTHLELQYDAPFGGHKQSGIGYEYGAGGLKAYCNVQSMFITKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD06</accession>
    <name>A0AAD8XD06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADP-dependent dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_581362</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363264.1">
        <property type="nucleotide sequence ID" value="XM_060505449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD06"/>
    <dbReference type="GeneID" id="85389348"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="27127" checksum="BBDD3C0E703EFC1E" modified="2024-05-29" version="1">MPTYVVTGARAGIGLEYINQLSRSPSNTVIALVRSTAPSTDLSALEAIRSSNTATTHILECDVSSEASITTLPGRLSAALNKGRRTPAKVDFLINNAATLQFAHQTSLTLDKTGLDVHMETNVLGPARLVQVLLPFLTARDEGEKDGVDAAYEGGGRIAAVVANITSGAGSLGWTSDGRVGMLAGYSISKAALNMLTVHQARELRGRGIVAVAVDPGHVKTASGGPGATVEVEDSAGGILSLLAGLKSADSGGFFLCNGTSVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDT7</accession>
    <name>A0AAD8XDT7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362681.1">
        <property type="nucleotide sequence ID" value="XM_060512365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDT7"/>
    <dbReference type="GeneID" id="85396263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF4">
        <property type="entry name" value="CYCLOCHLOROTINE BIOSYNTHESIS PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="170" mass="19203" checksum="5CD33594E920350C" modified="2024-05-29" version="1">MMAKRLKSLHNSSNVLVNGNFADWKKPDGTVAKLPAYYSTVSYRQTYIIRSFHQMHCLISIAEEYGHRANNVSSQWAPKHIAHCLNAIREAIMCLADATPMTYVNGFAVGHVTDDQQFMCRDWSALRKWANDPVRGIRYKNIAPEGAGYDNNTEIIPFPELSELEKVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDX9</accession>
    <name>A0AAD8XDX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_636071</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360190.1">
        <property type="nucleotide sequence ID" value="XM_060509227.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85393126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000196">
        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000182">
        <property type="entry name" value="MAP kinase kinase kinase mkh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1438"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="437"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="639"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="834"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1044"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1279"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="838"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="867"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="886"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="937"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1067"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1087"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1141"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1174"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1233"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1467"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1715047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1729" mass="187620" checksum="26CD75BB3853D59D" modified="2024-05-29" version="1">MSTSSRQRSATRSDTHDRNSSPFPSVPRSRDEIHNLDGFVFNVNDLPTHTSTTTSTTPKVLSPNLNGNGALSPYPQPRNSNLLSAGGLRPRASTASSVPTTPLLGLDPARPATRAGPPPPPAMYQNTQRHASSADPSRPFQVPPPPPPMSPPVQGQMSNMMSIPPPPPRFPSAPGATGGSGMMLPPPPGPPPGSAMAGQAPWHGAFGRMYDGRGGFNMPPPPPGQHQAYNPKLHAQVATGTTLSIPPPPPPNEHVMSATYIPQGDTYGEGVGIPGLGGFDENATFSATSQSSWPTNSQTSGDTAMTTPQDDVSGGRDRMYAQAMHSRGMSTTSNATSISTSSIHPELAAQWPLEKVLLWLATNQFSKDWQETFKGLNLHGAHFLELGSMHGGRGNFGMMHQQVYPRLAVECTNSGTGWDQPREREEGKRMRRLIRSIVTGRPADPSKVSSHGRKESVNHGNNLPSAGTDMAESPNVSMITRVGEHPKTDGRQTPIKAPGPGFGGRRFSQTRSTTMPTLNSTMSSDSSHRNIMKQIDGDGIRRQSPNASESGEGTFRPPPLRTDSPNGSPNPQSASLFPSSAGNMSASPHSTKFGHRSRNSTDSVSSNAAIYGSGIPPEATQMLRSGMNIADIIQATRNGEPRRLGQDGGRPSPQDSTGDRSAGTEPPSSAKDSKSFLSLSFLSRKNKQKKEDGFPSPDDMESPTSPALSFKPHSFGSRFGNNSETSLDIRPGSSFDVHEKDSAKSRRPGPNRVFALATMDGYNYRMCDITEAESAMDLRLVICSNLGLMDATTSQFYLTELGRFNHENPLDDQKLLNNRKHRADATGTLKFFIRQGGNAPQGSSHANGNPTHTSLDEEAYNRLNGLSRTRSSSSPPTSRQNTMTGERVDDKMLAQEASEYRAEMERKQREYLEKRRKAAGSGNTPESATTPYGIHGRTVDFDQPRQSPYEDKKPEVLFPVRKPPAPPSDPSATLLKANSLSRKTEHAMRSSADGAPTPRRPSTLFEDMELPGQNGDRKKKTSSQPVAGIGAALVGMGRGLGAVGVHANRRSKSPNRVSSQPALGNEYSDRVHRVASREISPSSMNPPQFPQSAPPQPHRRKSHGPDFDFLESEVSFEKPAPPPAPERGDDSGDDSDDGLFAIPIAAAKPKPTKITRIFDGDDSPDESTDKRPNLTVNTSRSKGKQLSVSFSSPKSLGSASNRTPEGEEDDALMSARSGKSSRRTPNTPQSESEDSKLGRRKSFVEKDVWANRPTTDALINNLDDFFPNLDLDQPVLEEGEAEANPPSPIAEGEEKEASKRPAPPQSPPSLRAAISNNRSFYNDNDTLGSDESTLKALERPASVASVAQRSVRRSGGLGRMKSIREVARGAHEANKRFTTTATTQPGQATQNTSVLMRRKSTKMFNANIVQIRPDQRGSMVMPQIPQDTIPKRQTTFRWFKGQLIGKGTYGRVYLGMNATTGEFLAVKEVEVNPKAAQGDKAKMRELVAALDQEIETMQHLDHVNIVQYLGCERKETSISIFLEYISGGSIGSCLRKHGKFEESVVSSLTRQMLSGLAYLHREGILHRDLKADNILLDLDGTCKISDFGISKKTDNIYGNDKSNSMQGSVFWMAPEVIRSEGKGYSAKVDIWSLGCVVLEMFAGRRPWSKEEAVGAIYKIANGETPPIPDEVRETISPLAIAFMLDCFTVNPLERPTADVLLSQHPFCELDPNYNFFDTVLYSKIRGKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEU3</accession>
    <name>A0AAD8XEU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_578085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364687.1">
        <property type="nucleotide sequence ID" value="XM_060505085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEU3"/>
    <dbReference type="GeneID" id="85388984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="45827" checksum="8E713FB0B5A0E510" modified="2024-05-29" version="1">MATAALISPSSHYGHPSSFSSGYQHHPAPGPSIAGMISPIEPRRPSDESETPHRQSLPSLSEVISGAKPSPYPPSQGSSMSGSQSFPSPFAPGPPRSYAESTDKNSPRPPVPASTFPPRQDALPAISDPPRPPPFAGRPPAPLGGFSGPQPSPPLKHEHMRDMRESDARAAENTGPYAQHSIPPPPTIYPHPQHPGQLPPGQVPLPAYPVSPRHAGPPPPFPYEAQRPTAHREDPEYGPARVRTHLDAWGYQDCFSRIGSATRTIYNFAEAYGKIAAEQQGAHHPLHDRLPTEQELNEMIDNVEYIRNSLDSVRQVVKESNERVRAAGKQKGYDDEDTPMYDGMNKAYGITEVKKRRGRAAPPGRCHSCNRIDTPEWRRGPDGARTLCNACGLHYAKLERKRQLEARQIRPKPSDERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF16</accession>
    <name>A0AAD8XF16_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_585875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361210.1">
        <property type="nucleotide sequence ID" value="XM_060505883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF16"/>
    <dbReference type="GeneID" id="85389782"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.20">
        <property type="entry name" value="Ub domain-containing protein, DC-UbP/UBTD2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032752">
        <property type="entry name" value="DC-UbP/UBTD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038169">
        <property type="entry name" value="DC-UbP/UBTD2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039869">
        <property type="entry name" value="UBTD1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13609">
        <property type="entry name" value="UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16455">
        <property type="entry name" value="UBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="173"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="248" mass="27516" checksum="1270EC7224BA98C6" modified="2024-05-29" version="1">MPLDKHINKPLRRHVWTSKGRAWTRVAIDRERRDFFDTRVTGRPEVWQSLRAALEIIWDPVSQGAADDGTDGLATAQGILNAAEITLPTGDLAQGAYDQLGNYYPLSEWLVADPTNLVEDDATIDGADEALSTRDLKDDLAGGEETTEELDEDDNVRRREEKGKAVVDARDQLSVLARLSETARDVTVSFVKSDSVRTVARKIQEQSGLASTKKIRIAYMGKILKDNLSLAEQGWAEGHVVNALVFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG54</accession>
    <name>A0AAD8XG54_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Unsaturated glucuronyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_742782</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362305.1">
        <property type="nucleotide sequence ID" value="XM_060513118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG54"/>
    <dbReference type="GeneID" id="85397016"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000048">
        <property type="entry name" value="Unsaturated chondroitin disaccharide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="526" mass="58619" checksum="0E9F74099270E5D1" modified="2024-05-29" version="1">MSSEPPLSISTLPPEELFVDRISETSWSDAAIEANEWPTFQPSMPLSTHLTELFEENVTAKVCRTATTSLQEQISPISGEIRKTPIAFPEIIPQDGPNAGQYEFRDPDFWTCGFFPGTLYALLERTVKHPQMMRLTDVGSGLSVASLRQHLRGLCKIWADPLHDMAGRTDTHDIGFIIMPALQRDWELNGNEKSLASIVRAAHSLATRYVPAAGAIRSWDCLLKKDITVTDMTTNLLAIVDSLCNLDLLFYAAAHTGDSTHADIATTHARTLLHTHLRPESDGYRGQLYSTCHVANIDPATGDLKWRWTAQGYANDSTWARGQAWAILGYAQTYQWTRDRAFLEAALGAAEYFLYRLDTAPSCVDMPVVDGDTTYCCSRDGLRKKTKGRRVPLWDFDAPIQNAAEPLRDSSAGLIAANGMLVLTQALRGIEENILARRFFDAAVEIVRDTLDYSLADEKAQFTRASSEAGLEVEDSIADRCFDGIIKHGTANNNENARRRYWNHGLVYGDYYLVEFGNRLLNMGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGM3</accession>
    <name>A0AAD8XGM3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367299.1">
        <property type="nucleotide sequence ID" value="XM_060513897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGM3"/>
    <dbReference type="GeneID" id="85397795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="46"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="641" mass="72967" checksum="47A1A1EF77172891" modified="2024-05-29" version="1">MLEEALPLYEPLDAGKSEIRLLEYVSFSGQPSLRLRSVSLDVKPVYTALSYVWGDASITEPIFLNGQEFQATKNLFHALQYLQDHWIDTFPGRHPQGFRVWVDALCINQKDVAERNQQVQLMRRIYARAELVFSWLGTETKEIGAAFETINLVAHEMGKVVGQRHIGSVEPHELISWMQDWPQLILADIEPENDWHSNQSWKSMRSLFNLPYWFRVWVVQEIVLAENLVLLSGKSSIDWIALFLTCSWIERLKEVRTYLQKPLWMVESAWLSITSSDRVPWHNPMRLMKAKHLHKRPETLSADDWESWGWQLMSWNHTLAATDPKDSIYGLLGLTKLPLIPDYSPDVSVASVYIEYFAQYLAFWKRTGQGKELELLPMAGLHMTTGATPPLVKAGLPTWVPNYPYAWREPNRSFEPITGDADNGVFGSDVPDANISGNRHLLVSGIRIGEVLRNLPTPTLFDTEHKLVKLIEQLITSNTQFPNGMTAQEAVFRAVFESGGRGEAVLFRYPEARAEMALGFLFHLMYIDREFAGEPLGQGLFELLGLDDSNSEAFNNSISKAFISSHGIDGPWLERLVEWDPEDDLSPEVHDQVKSGVTAWDWRDRRMLQIGGGGDNYIGVSRQNMAEAGDVILGWLRAVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHF3</accession>
    <name>A0AAD8XHF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CAP-Gly domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571144</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368169.1">
        <property type="nucleotide sequence ID" value="XM_060504382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHF3"/>
    <dbReference type="GeneID" id="85388281"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="5">
        <location>
            <begin position="175"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="240" mass="26439" checksum="304138E282289B8F" modified="2024-05-29" version="1">MADVPLHVISENSSSERRITPSWTITQLRSKLEPITGIPPSSQRISLKTASATVSIEASDEDSAYLTGFPLAPYAELHVTDTRPAGARPNFTDTSGVEKYVMPEEEYAKKSDSVLAWKKAQKLGRFDPDAPSHEQAKIDALQQEIEQKGIQVGKRCRVGGEDSRRGTVRYVGDVKEIPGGLGPWIGVHLDEPVGKNDGSIAGTRYWGEESTLKHGVFVRPERVEVGDWPVLDDLEDMEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG1</accession>
    <name>A0AAD8XHG1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_774324</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366491.1">
        <property type="nucleotide sequence ID" value="XM_060515418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG1"/>
    <dbReference type="GeneID" id="85399316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF131">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="85"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="46647" checksum="C4AB4C73A14C6618" modified="2024-05-29" version="1">MISRDNRNLTAECMISAWAIIICHDDPNVKSFPDQCPTAQRCLYPTCRDCRDNTSRRSGPVRSLVTVVWAVNLTAFVLVGIIVPLRVIVRCTVTRNFFSDDVLVIIAALFTFAVCALLPIATDLGLGQHSWNLDAEFLPDNTKSLLQLIFIANTLYPCAIAFTRLSAISSFLRLMTHKSARWIMYGATVVTGGFGLASVFAVIFQCKPITAAWDLSTSSATCYPFIDFLHASAALNIAIDMLLCTLPLPYIWNMKMTTGIKVLLTILFSFSGLSCAAAILKLVNLEPLSDSDVTYNWVSWVLCSIAECTIGIACMSIPPITPLFTKCSRNKPPTPRKERSKSLRYTLFAEKPTFSRAVAPRVIRPMATPWKDRPLERTVNPDFKPEFHWLRLEQQEYGQCWDRTPQSTKADQVLGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI95</accession>
    <name>A0AAD8XI95_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_779223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364435.1">
        <property type="nucleotide sequence ID" value="XM_060515510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI95"/>
    <dbReference type="GeneID" id="85399408"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="560" mass="58265" checksum="8D472B7F6760052D" modified="2024-05-29" version="1">MVDQGTQGRWYRIAGKLLNRGLIGDILGTPGAIVSQVLSSPATTTQENVQAEGTPAAAATTQAAAAPAVTTAAAAPVAATTTPAAQQPAASPAATTKQEQQQAATTPVAQASAAAATTSQQAAQASSTIVAAANPPAASSSSSSAAAAVSSTPAAAATTVPVAAENAASSPVLSQAVPPEATGTSVTGVGAGSASSTRSGVTNATQTSSPNYENTSSSSSQGPLVATGVVLGIVVLMGLSLLIFWCYRRRRRAARHVHEPVALESPSNEYGPASPFRDHVDQSYTEMTENRTVSSEDEFTIQHPEPGYQPPSQPPMSPQMQDTPRTNPYAASPFSYAQAQQYVQSLAGTGTFGFPPPPPIPEPSPIRIFRWPTRSSRSGNSTPSVFSGFRTPKTPTRALSRASRSTVSSMLWHGRRDVARRTIIRTPGSQKSAKSAKSRTNISSHSPESTMPEGLHTPILDWLHWIRGHQQVEPDPEMNHRKSFASTTESSVSETSVASTASSGVFSPTLLSYHPPANTPSVTTETIQYLPLPLFKKRASDSNSEVTVEASGTVRIPSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ97</accession>
    <name>A0AAD8XJ97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">4-dimethylallyltryptophan N-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.261</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_697378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:34435"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58209"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:67248"/>
            <dbReference type="EC" id="2.1.1.261"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis; ergot alkaloid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.261" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366070.1">
        <property type="nucleotide sequence ID" value="XM_060511381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ97"/>
    <dbReference type="GeneID" id="85395279"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="10">
        <location>
            <begin position="45"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="40103" checksum="DF35363353800D72" modified="2024-05-29" version="1">MASQSKMSNMPAHGSVLDIGGGSMSSTILEDLQRHNDAGVGSSGEAPTMPDELLYNDEGLAIWAEVIFTPEFYQTRDEMVLFEKNSEEMATVYIPNDATMIDLGAGDMRKVNFLLKELAKHGRNATYLALDISNHSLTCNLEALAPEHAAGSVRMAGLWGDFKAGLAFCDDIPSPRVFLSLGSVLFNDPWKKAVASLREWAALMRPDDLILAGMDGHDVTSTKVWAAYHTHPILFERFFHNGFKHANVLLGEDVFKPEDWDICGEIEEDEKRHRFFLKAKRDVVAEKEGKTLKQGLEIDWFDAHKRNEEDVHNMCAEAGLEVVKSWAIEGSDMRQYLMRTAAIENSIDETDSAIYVRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK09</accession>
    <name>A0AAD8XK09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal ion transporter metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_117263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368725.1">
        <property type="nucleotide sequence ID" value="XM_060501130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK09"/>
    <dbReference type="GeneID" id="85385029"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF101">
        <property type="entry name" value="MANGANESE TRANSPORTER SMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="561"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="591" mass="63855" checksum="97E1FC11B2C11141" modified="2024-05-29" version="1">MKPTWLDEPVAQQGGSSRRSSVSPFTADYTISQTLHGQSHSESRRLSDVPPDFINLNAIVSSQGTSASTEDFAPNTLKKQTRIDDEGPFSLLEGPTLPLPGHTVHKREKNWINRRWSDLITFGKFVGPGFMIAVAYIDPGNYATDIAAGASYHFDLLFIVLLSNVVAIFLQALSIKLGTITGLDLATACRVFLPKWMNIIVYALAEIAIVATDMAVVIGTATAIHLLIPKLPLIACVVLTIVDVVFIVVFYRPDGSMRGLRLFEIGVCFLVLGVVVCFCIQLSLIENTTVGQVFRGYLPSSSIIQTQGLYQSCGILGATVMPHSLHLGSGVVQSRLKDFDMKEGNLQELPRFDTMTTVDSYNKVFYFPSMAAIKHCMKFSIAEIVFSLFIFALFVNSAILIVAGSALYQGQTSLASDIFGMHDLLANSISSAAGIIFAFALLLSGVSAGLVCTIAGQLVSEGALNWRMRPWLRRLATRLISVTPTVIVVAVAGQSGLSNALTGTQVVLSTVLPVITAPLIYFTSFDKYMTVVPGAASYGSDTGVVPARRFSAVGVKMANSWWVTVLAVLLWLMITVMVVANLVLLVLNAHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK52</accession>
    <name>A0AAD8XK52_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_84700</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368909.1">
        <property type="nucleotide sequence ID" value="XM_060515953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK52"/>
    <dbReference type="GeneID" id="85399851"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF1">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 18" id="KW-0732">Signal</keyword>
    <keyword evidence="17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042149344" description="CFEM domain-containing protein" evidence="18">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="19">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="92"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="259"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1728854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="308" mass="31838" checksum="6DF583021DA32BE0" modified="2024-05-29" version="1">MRRRFWVRAFAITALLGNVCAQLDSLPPCGITCVNNVIAKGFGCASGDNTCLCKQQDFVFGVRDCASQSCTADVAPKVNEYVAGLCATATQVPPASTPPASNPPPSTPAVQQTTPPAVLPSTSQPPPSPSSSSEPPKPSAAETPASSEVAKTAPWETSGNPVTDTAQAFQPSSAVSTTLATSTRSLSSTSSWSTSTSTGARPSQSGSASETGAGNLESDAAGLSSSAKIGIGVGAGVGVLAIALALWLLIRRPKNRTKSMQISGPMPGSGRDYTGGFIGMKDKNHSELEMKSRRYEDMLPRQSPRRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL47</accession>
    <name>A0AAD8XL47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_568629</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369445.1">
        <property type="nucleotide sequence ID" value="XM_060504095.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387994"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000001">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000015">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000207">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="192"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="287"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="379"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="471"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="563"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="655"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="729"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1103"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="68"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1234"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1238"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1729390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1304" mass="143073" checksum="E48147EACE690B35" modified="2024-05-29" version="1">MVDDSALAAAAAIVQSLAADGTTPMSLPFKVDARIELPGRDTPAKRSLENELAKLAQRIEKLESRAHASVAFPETPNEVHGSLFGDDSDGASPSSSNSRTVAAGPTKFQREGTATADPSLADSPLTDEALESLQEKVLDQEKGISSARQEISSVSAQLLEQKELQEQAFFKIEQERVATLERELWKHQKANEAFQKALREIGEIVTAVARGDLSKKVRMNTVEMDPEITTFKRTINTMMDQLQVFSSEVSRVAREVGTEGLLGGQARIEGVDGTWKELTDNVNVMAQNLTDQVREIASVTTAVAHGDLTKKIERPARGEILQLQQTINTMVDQLRTFASEVTRVARDVGTEGILGGQADVEGVKGMWNELTVNVNAMANNLTTQVRDIIKVTTAVAKGDLTQNVQADCRGEIFDLKSTINSMVKQLQQFAREVTKIAREVGTEGRLGGQATVHDVEGTWRDLTENVNGMAMNLTTQVRAIAKVTTAVANGDLTEKIRVPVRGEILDLKNTINTMVDRLGTFAFEVSKVAREVGTDGTLGGQAQVDNVEGKWKDLTENVNTMASNLTIQVRSISTVTQAIANGDMSQKIEVEAQGEILVLKETINNMVDRLSNFCNEVQRVARDVGVDGKMGAQADPAGLKGRWREITTDVNTMASNLTTQVRAFSDITNLATDGDFTKLVEVEASGEMDELKRKINQMVSNLRDSIQRNTQAREAAELANKTKSEFLANMSHEIRTPMNGIIGMTQLTLDTDLTQYQREMLNIVNSLANSLLTIIDDILDLSKIEARRMVIEEIPYTLRGTVFNALKTLAVKANEKFLDLTYRVDSSVPDHVIGDSFRLRQIILNLVGNAIKFTEHGEVSLTIKKADPVVWACGPDQYAIEFIVTDTGIGIAADKLDLIFDTFQQADGSMTRKFGGTGLGLSISKRLVKLMGGDLWVKSQHGQGSEFHFTCRVRLSDLGVEIIEKQIKPYKGHEVLFVDKSQSGYGEQIETMLSLIGLKPVVVESEKNPILTSVRDAQAMPYDVIIVDSIDTARRLRSVDDFKYLPIVLLAPVVHVNLKSCLDLGITSYMTTPCTAVDLGNGMIPALENRATPSLADNTKSFEILLAEDNRVNQRLAVKILEKYHHVVTVVGNGLEAVEAIKAKKFDVILMDVQMPIMGGFEATGKIREYERSLGSHRTPIIALTAHAMMGDREKCIQAQMDEYLSKPLQQNHLIQTILKCATLGGQLLEKNRERDMAQQSRVKASSNEHPQSHLRPPLETRSFTSKEPIMGPSPASPAVATADQEDPISRARNGLSDSRSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL59</accession>
    <name>A0AAD8XL59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL11m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_716258</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369461.1">
        <property type="nucleotide sequence ID" value="XM_060511834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL59"/>
    <dbReference type="GeneID" id="85395732"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000005">
        <property type="entry name" value="Mitochondrial 54S ribosomal protein YmL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000004">
        <property type="entry name" value="Mitochondrial 54S ribosomal protein YmL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_uL11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 11" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="10">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="9">
        <location>
            <begin position="76"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="155" mass="16596" checksum="C9495DDE39D0CF44" modified="2024-05-29" version="1">MSKRGATIADQVVKLIVGAGQASPSPPVGPALGSKGVKSMDFCKEFNARTAHIITGTPMPCRVTVRGDRSFHFDIRTPHTSWLLLNAAEVPVGKKGKRKGATNPGKETVGTVSLKHVYEIAKIKQTEMRLSGLSLEAICRSVIYQCKSIGINVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLQ6</accession>
    <name>A0AAD8XLQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_604479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369688.1">
        <property type="nucleotide sequence ID" value="XM_060507276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLQ6"/>
    <dbReference type="GeneID" id="85391175"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16485" checksum="259401EE7A929743" modified="2024-05-29" version="1">MTSERQDLQYANAEIGSVRRDLDKMTRQADEDRRKFENDSATLNDELRAAYELADQRKMMLIRHDFGLEWYKERSADADSRADGLESEFKSARTIIEQFRKELAARTIKRDEAMEKSDEIGKQLNERSAQLAACTTTSLSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMG3</accession>
    <name>A0AAD8XMG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370063.1">
        <property type="nucleotide sequence ID" value="XM_060513474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMG3"/>
    <dbReference type="GeneID" id="85397372"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042062593" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8811" checksum="BA62DE6C0B1AC5DA" modified="2024-05-29" version="1">MQLNNLLVTAALSFSMASAYGVGNPGSTCTPGGFHCNPYEEPNGVTYQNAWCPSQCDPRDGRKDPKGCNWATCDKQTPNPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNC5</accession>
    <name>A0AAD8XNC5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_566243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370509.1">
        <property type="nucleotide sequence ID" value="XM_060503838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNC5"/>
    <dbReference type="GeneID" id="85387737"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="51633" checksum="2ED572E4127FDC15" modified="2024-05-29" version="1">MATQTGTASRRPKLSLSIKTSPAPHTRINKSFSVIDPKDPTTFNTLSNVYVTAIERSTPTASEPLTAINTSQTQPSRLQNGSKTPQLRIQTPYAVSYPETPLTAHPLSPGVAMEITFPSTMTATPPLSAGPVEPNQGPQMFGFSPIDTKTPLTAIGLIPNQPEARSQRRRNNNLTLAGSKLPYTHPRSLHSILRNSPLPPPSAKTPISPRRQSLRLQEKAARRVAYNSPIEQTITTETYTKSHIDLLVEDVVSPASPAAAAATAAAAETAPAPTQEEANAVLDLAMAFTSDETRDGGMTPGPFEEMRRRMAGLAANSPPVSPSGGIRKRTKRKEKKRRWVWTIGNQEEDEENLGGAVAALRAAEAAAAQTPVLSVPQRKTVVAPPLMVEVQTCGDLPTPSVETFEEAAGEMEDVEMSDTSSVSYSCSDRGLTPGDMEMDLTTPTVPKRLVSQCDRLGSVDLINPDTGSRRDTPIPPDMAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNX9</accession>
    <name>A0AAD8XNX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_333999</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370809.1">
        <property type="nucleotide sequence ID" value="XM_060502432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNX9"/>
    <dbReference type="GeneID" id="85386331"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="375" mass="40459" checksum="D7D41F6D84DCD220" modified="2024-05-29" version="1">MASFSFGFGGDDIEDDSVPVPAAEASAPAAPEPETPQSAAAASAFPVPGKPQLPPTAHDLQDMLSKLPSKVAFGNLDVTLDDGSLIKIPRRELWDVRVQLMAEDEAAGDGADAEGLGSHDVKTGVYEGGFKSWESSVDLVKVLASGQYLDLLKQRPLRVIELGCGTGLPSLALLQWTMRNPAPRSPLVLTLADYNPTVLQLVTLPNFILAWALERREQNAALEEAFAMGDELELTPEVLQQFKEFLTSSQISLNFISGGWSVELVDLLYETQSKLDGSSSFDTLLIGAETIYSPFALDAFNEMVLAILNREQSQRSSCQSQALVGAKRLYFGVGGSLDDFVDKARGRGATVTQVREEAEGVRRGVVRCTLGSHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ00</accession>
    <name>A0AAD8XQ00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein of 70kDa MW N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_715237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371459.1">
        <property type="nucleotide sequence ID" value="XM_060511725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ00"/>
    <dbReference type="GeneID" id="85395623"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000298">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="102"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="412" mass="45494" checksum="474F5C8F9794DB4E" modified="2024-05-29" version="1">MTDKLPPNLLALFAPRPPLRWVAPPDHAPEARRTLPVSGLAEFLPALQQYKEEDDYKPTESWLQMRDRKKLEKQAAVEKLKTEGPKDFKPHEDPNIRGDAFKTLIVARLSYEANEQDLEREFGRFGPIERIRIITDTHAHERPKKKKKPHRGYAFVVFEREKDMRAALDACDGIRIKDRRIKVDVERGRTVKGWVPRRFGGGLGGRGYTKALPARPMGGGPGGNFGGGFRGGFRGGFEGGRGRGGFRGGGGGFGGRGGFRGGGDFGSRGGDRGPNGYGAPRDAPSGPGRSFGGDRGDRGDRSFSGGGYDRGGGRSYDDRSGGSGGGGYRDGGRFGDRDRDGGRRTGSNMEPIRPRGEGGYRDRGDRGDRGDREDRDRGRDRDRDYDRPRDDDSRKRGYEGGGYEDPRKLRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX1</accession>
    <name>A0AAD8XQX1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3752 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_645760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371844.1">
        <property type="nucleotide sequence ID" value="XM_060509884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX1"/>
    <dbReference type="GeneID" id="85393783"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="197"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="38014" checksum="EB962B15B289A5F9" modified="2024-05-29" version="1">MSSIGPQMPPHLTKRKRTPDDQGAGSPPPKHTRNNTDEIDLDDDDSDDDAYGPIAPSAVVAAASNNPTPSSKPSIGPTLPPSNPTNSSEIPLDDSASEDGYGLTAPRASAPAQEAPKTKPSIGPSLPPKQAIGPAMPPPDHRPSAADSDSDSDDDYGPALPSSTTSVQRAQAAAAAAAATASQGPAAPQRDDWMLAPPTQSGYQERDPTKLKNRKFASGKSSAAAAGGGGGGISSIWTETPEQKRKRLEDAVLGRGDPTAAGNEKNQQPRRTKEEVERERRISDNIASTRGKSMYEEHQANKKHGGKPGRDEEEEDDPSKRAFDKEKDMSLGGKIGTAQRRELLNKAKDFGGRFQKGSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR07</accession>
    <name>A0AAD8XR07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_596564</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371827.1">
        <property type="nucleotide sequence ID" value="XM_060506864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR07"/>
    <dbReference type="GeneID" id="85390763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23952">
        <property type="entry name" value="Utp17_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057644">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23769">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="WD repeat-containing protein 75 second beta-propeller" evidence="10">
        <location>
            <begin position="539"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="888"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="955" mass="104640" checksum="E0E80FF464B875E4" modified="2024-05-29" version="1">MAGASTPRSREDQKKRKREQNERDGQAKRLRQKTKTAGKANGQKNGNTDADDLRDGALNVLSQLQKNLTDDQIETELVKLGDTEAQEAGWQVSLPMGGRMADIDPIFAENEKYLIVTYNTSLQIYSVAESLLIRRIALPVVQNTYAEKSSAPTIVATRQSQLKPDFLWVACSDGRVWRVNWKKGTGVYDEFRTQSQTALDLSVASIEGQKKTTEVLYVSEGKKHAKGEVVAYSGPDFKQPTAEVLFATKQVDHAIHLLRSSPNGKTIVGATKDGLVVGTLTPESEWEFFTFDTTDIICALDIRITHSKDNSLVLDLIAGGARGAIYFYDDILRKLQNLNGPKSKREALTSRKFHWHRRAVHSVKWSKDGQYMISGGSENVLVLWQMDTGKKDFLPHLSGSIENIVVSPTGASYAIHLDDNSAIVLSTAEMKPSTYISGIQSAARFTSTPKDLLVKRVWSVSDEVRHPVPAALNPAEPSRLYVCTGTGQQSMLAGEIQSAPLLQSFDMESFRSVSKQALARTQPTDVNITSKGNPISEPRITHVAFSQDGRWLATVDDWQPPKRDLEKVAPEAREQFVRERREIYLKFWSATAGEEHFALSSRINSPHVTSRPETVLALAADHTTNRFATLGDDGTARIWQSKTRQQDGIASKDNAGEVLHSWSCTVAVGLGGNVGADALTTTGETTGERSGSLCFSEDGSTLFVAFGHSNDGGIYVIDTKTGEIRSTLENMWKGHIRRLQVLSPYIITLSDDLRVFDVVADELQYGLQLPSGRNATAVKEFSHLAVDRKSRTFAVVVPGGQASQLAVFKPEEPALLCVRRIPHRITSLVSTGSSSGFVAVDDAAQLWSVAEASDPAAVALSRPLEDMQLDVEPVAGDVILDDAIEDEEMASDNEQETEAANGEEMDLDDDDAQPAVINRQKLAELFDAAPAFAMPSVEDMFYKVTGLLATKPLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYT1</accession>
    <name>A0AAD9CYT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368869.1">
        <property type="nucleotide sequence ID" value="XM_060510182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYT1"/>
    <dbReference type="GeneID" id="85394081"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="161" mass="17399" checksum="56FF8BC0DC5CA29B" modified="2024-05-29" version="1">MASGRDADSDGVNGRTADCQSPMDTTYDDGVSQGPKGQRHLAFPNHAHLGCSSANEGQGQIRPVYGVSESSRASSDRQEKDFSNEPGTSPVEWQSLVRNLLAFSPPKAGIRKEKGATKQNIPAPKDHSQKPGRIGTSTWGKWEICHRERSLKPVPTFTAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZF9</accession>
    <name>A0AAD9CZF9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_50556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369378.1">
        <property type="nucleotide sequence ID" value="XM_060503298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZF9"/>
    <dbReference type="GeneID" id="85387197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="25622" checksum="0D362E0E799C074D" modified="2024-05-29" version="1">MDAAHRFTYFGALPPELRLQIWTEALSVPSVWAVNQEATETNNANTSHLPLIMNHVGPAPYLAGLACQESRRLMEQLYAKPIHRPTHSAASSATHWIDLQKTVVSLGDYRSAGALLDAFTFEDLARFRHAVLQSSRFSDMARLCQRLANSCPGLSTIIIHTNHAGCLFTDLPCEPLTQDMAALFVNILEDPTAGLNCNHYDTVHFRSLLLDYFGDSPPTLHLASPPGATRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0S4</accession>
    <name>A0AAD9D0S4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_567061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370067.1">
        <property type="nucleotide sequence ID" value="XM_060503919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0S4"/>
    <dbReference type="GeneID" id="85387818"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="7">
        <location>
            <begin position="221"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="111"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="32189" checksum="D4B08443F94C5AF2" modified="2024-05-29" version="1">MRDQTGELTIQLKEARSQSESLEEELAEIQKHLSERSREAERMRGLLADVDERADSKVREMRARMEAAIEERDRMEDESSTLARRKTRETEELKQKIRDLERDIKTLSTEKEELEGREREWRRRREELESVEEKAEAEVKEMRSAVSDLRTTLDASEQQVRDAERQKSDLRRLLEESKQRFDKVNKELKTVQTKLGASVTSGRSSMDSNRSGLNGGPAAGGAGGSADTLYLKTIMLQFLEQKDNKLREQLVPVLGRILKFDKSDEQKWKSAIQHITVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D109</accession>
    <name>A0AAD9D109_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_425853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370217.1">
        <property type="nucleotide sequence ID" value="XM_060503009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D109"/>
    <dbReference type="GeneID" id="85386908"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="24168" checksum="208E9F33931C0151" modified="2024-05-29" version="1">MSKFWFFVAGSAKVPHQYSLQTSLDFLLLLSSTPLNRRFTVVNSSVAGEKGFQREREDADEKDEEEESFEEVVVVESRELARLWPCGLSSGVDGECRRRVVVPKGSYSQSQQGEQQSVVVVVFNVGVDGCVAGAPGAVEYGQAMSSSAFASVVSVSSVVSVAVQPGVETPRRRRPRCRRWRRGRRGDDGSPSALSNRPVRAGVGVTSSLRVITDVERVIQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1A8</accession>
    <name>A0AAD9D1A8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_566563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370518.1">
        <property type="nucleotide sequence ID" value="XM_060503861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1A8"/>
    <dbReference type="GeneID" id="85387760"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3110.10">
        <property type="entry name" value="protoporphyrinogen ix oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.20">
        <property type="entry name" value="Protoporphyrinogen oxidase, mitochondrial, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF17">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="60323" checksum="2C8F27156E22C17A" modified="2024-05-29" version="1">MSRRPPSLESIGSRGSVGSPIDPRFRKKVAVVGSGSAGIAALWALNRSYHDVYMYEASSRLGGHTNTVTWKNGKYETRVDTGFIVLNTATYPNFINFLKRVKVDTVPTEMTFGVTRDHGLFEWAGKSLDSIFAQRKNIFSPRMWRMIFDIIRFNQFALDLLMAEDENDAAAMNGYSKGGKREETIGEYLEREGYSDAFRDDYLIPMTAAVWSTSPDKCTLNFPAVTLVRFMWNHHLLSTVATRPEWLTLKKCGKSYIDAVMSGFPSNHLFLNTQVTQVTSEEDGRVRVHTHNGKSDVYDHVILATHGDQALRIIEGSATPEEKEILSAFQTSENSVILHSDISHMPASEKAWSSWNYLTLTSPSTGKQNIDQVSLTYNMNIIQHIPRETFGDVLVTMNPLHQPNPDTIQGSFTYRHPLYTPAAVRAQKLLPRIQNKRGISYAGAWTKYGFHEDAFSSGLHAAQDHLYANLPFQFVDSTYSRGRKPSLGLADLLVRLVILLIQVFVIRVLERVAGAAETAIYGRRNGWRRSLKSGKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1N2</accession>
    <name>A0AAD9D1N2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_424802</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-methyl-UTP(out) + UTP(in) = 5-methyl-UTP(in) + UTP(out)</text>
            <dbReference type="Rhea" id="RHEA:73523"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:63527"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370204.1">
        <property type="nucleotide sequence ID" value="XM_060503005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1N2"/>
    <dbReference type="GeneID" id="85386904"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000088">
        <property type="entry name" value="Mitochondrial carrier protein RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="57"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="177"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="293"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00093195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="42603" checksum="A74C6629ED2D9395" modified="2024-05-29" version="1">MAHAPASAEFMSATGDRPAARRAPDTTSYPTSRETGDIIPDTKQNPAVGGEKESPFAKSWVHFVAGGVGGMTAATLTAPLDVLKTRLQSDFYQAQLRASHAARAQAVGTLSPYRAALFHLRETFQILGSVYKIEGPRALFKGLGPNLIGVIPARSINFYTYGNGKRLIAEYVNGGEEGAGVHLAAGVLAGVTTSTATNPIWLVKTRLQLDKNVAEKSGGVQQRQYRNSWDCIKQVLRTEGVRGMYKGMSASYLGVAESTLQWVLYENLKNRLAAREERIVASGREKTFWDRTVDWMGNAGAAGGAKLVAAILAYPHEVARTRLRQAPLANGQLKYTGLWQCFRVVWIEEGFMGLYGGLTPHLMRTVPSAAIMFGMYEGILRLFGASSKANASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1S1</accession>
    <name>A0AAD9D1S1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3074 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_747127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370863.1">
        <property type="nucleotide sequence ID" value="XM_060513384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1S1"/>
    <dbReference type="GeneID" id="85397282"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024500">
        <property type="entry name" value="DUF3074"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370:SF1">
        <property type="entry name" value="DUF3074 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40370">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11274">
        <property type="entry name" value="DUF3074"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3074" evidence="2">
        <location>
            <begin position="109"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="369" mass="39372" checksum="E43B78785F184206" modified="2024-05-29" version="1">MNTEDENLGPLVRLWGLRTEQLPAPSATTADLAPFLIAVLQEAVPFIDAVAPKDGTARPNEWKAKGTKTFPESTAPVELYERIVPAAELEKEAARNQLPNSSSVASETWACRRSIHKDRPGKGTAAWEEFVKCFKDDHVEAEKAFTPNVMEAREALAWDCSGIVVDEGGLSWEDFKVGVSEIKHKLGMPLKNRVFPVLIISARAKGAVDEFVVVSIPVSDLAASEHGKLVKEKAVVVGAYVSVERVRKLPTGAIEWIMATASDAKGVLPAWIQAKAVIGVVAKDVALFLGWIAEEREKGTSVGKWTAVKGNGGGSEVPNRKPSMTLEDAESSMQGGRTSRQGVSSRNGKEPVAGGTNGGGSGTNGQVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D247</accession>
    <name>A0AAD9D247_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_788156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370326.1">
        <property type="nucleotide sequence ID" value="XM_060515674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D247"/>
    <dbReference type="GeneID" id="85399572"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="3">
        <location>
            <begin position="59"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="54336" checksum="F2C22D8D9787BD2D" modified="2024-05-29" version="1">MASGRRVINPSSRALANLQSGGFIDLENEASKLPQYDPATCPDGVIDLSGAINGLMDDVLAEEMNQFSKNYDFVKATRYGDVMGPKELAKAMSGFINRYFGPARSITSDDILVTNGVTSLIDMMAFGMCDPGEGIVVITPTYMMFPHDLYAKAGVSLINVNPEPIESQFDEQYAPLLIEAMSRAYAVALEDGIIPKALLLCNPSNPCGRTYPRTTLVEIARFCGQRNMHLLSDEIYAMSTFTGTTDTHGQAIPPFTSVLSIRDDPPRGVLAENIHCMYGASKDFGCGGLRLGFLVTRNELLWRCLRRLVLFTWVSSFSAAFFTHFLLDGEAVGRYLKTYRERLEAQYGVTAQLLKENGIPFVPANSGVFIFIKLTSWLGHGQESAELDGSREMILCRYLLHEAGVFLSPGELSLSTDPGCFRLVYTDKWDYMPIAIQRLATALKELKQRPTSQSSSSSMNGQNIKGTMDAGEDLTRVSRRTSIARFLLCRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2A7</accession>
    <name>A0AAD9D2A7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_378546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370714.1">
        <property type="nucleotide sequence ID" value="XM_060502699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2A7"/>
    <dbReference type="GeneID" id="85386598"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="31856" checksum="D86F66496053BD98" modified="2024-05-29" version="1">MTIPYYLARSGTDAVNTRLHAPQVEALYPHLYFTTTTASHDTNINANKCREPRERNMETICASKSAVAASSTSSSIPPPRYLPSPGLMLMVLWAHRIALHPRPSRSSDGRERPPTESQLGTSVLILYPNFANLPSDGMETKRETKKQTKAASQNGHFRTPGLAHGRCLFLSTFLSITFHFPAVQLLLGRQAAAWGGPIHWPGSRSPVSEIPSTITIWHQIVSFPSLWKSFSFFSLHCLLGVLEVLGFLLISGPVPCRPVGLGVYYRDGSTPAFSSTLPACPASPVMTLGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2I7</accession>
    <name>A0AAD9D2I7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Unsaturated glucuronyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_714921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371477.1">
        <property type="nucleotide sequence ID" value="XM_060511684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2I7"/>
    <dbReference type="GeneID" id="85395582"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="462" mass="51929" checksum="58B561E0355D67F1" modified="2024-05-29" version="1">METVAGLTTPPFSSAEMIKQGAKSLAASLFSSKVTAKIWGVAQQSFSSSSPPTLFPEYTKPGGTKYVYRELDFWTSGFFPGCLYLLLERRRRHSHLLKQLGWSVEDEPNSLHLEFACKWWTETLHPNAELKTTHDLGFMIFPWARPAWELSSDRKSFETAITAARSLYSRYDATVGSIRSWDVCVTKRYKFLDPSQDFLVIIDNMMNLDVIFWAASQLGDDDMWSAAVKHAETTREHHIRPDSSTFHVVNFDQATGVPKEKITNQGYSDTSSWSRGQAWAIAGFVQTYGWTRDQSFLDTAISCADYFLEQLPSSGIPPWDFAAPKDMAQPPDVSAAMIAAYGMLLIHEALTALGRSSTYLRTAIGLTRAICDNHINRGGSYVKSQRSIETVEHGTVVEEVGWDVDMEAEPETILNGATINNYEFAPRRWANHGLVYADYFFLLVGNKLLEMGVGELFNDNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2R3</accession>
    <name>A0AAD9D2R3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_599697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371089.1">
        <property type="nucleotide sequence ID" value="XM_060506996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2R3"/>
    <dbReference type="GeneID" id="85390895"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="15"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="335" mass="36018" checksum="D0DC7727D6AA4106" modified="2024-05-29" version="1">MASTMRAVDIKDGKGPKENLFINADTPKPTAGEGEALVKIKAFGINRMDQIQRLGNYPLPPQAPKTLGVEFSGTVESFGSGDHGNFKTGDEVFGLAYGGAYAEYIAVNSKMLLHKPDFLSWEQAAGVPETWITATQALFLVGEFSKGKSVLWHAGASGVSIAGIQLAKDAGASAVYATAGSNEKCDFVVNEIGATAAFNYKEVDWAEKIKEATGGKGVDVIVDFVGGGYFQKNLDVAARDARIVLLGLLGGPNIEGANIGPLLYKRIRLEGSTLRSRDVEYQGKLRDRLEEYVPHFKTGKLKVVIDTVLPWEKIQEAHAHLEANKNSGKIICTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D383</accession>
    <name>A0AAD9D383_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371464.1">
        <property type="nucleotide sequence ID" value="XM_060503706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D383"/>
    <dbReference type="GeneID" id="85387605"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033768">
        <property type="term" value="C:SUMO-targeted ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032183">
        <property type="term" value="F:SUMO binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140082">
        <property type="term" value="F:SUMO-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049627">
        <property type="entry name" value="SLX8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47094">
        <property type="entry name" value="ELFLESS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47094:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="356"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="47122" checksum="C6B65355986AAB9A" modified="2024-05-29" version="1">MPGLIPFLPTPPLPQPTRTASGQSVNHLSDLDRVAARGGSSQAPIELDDDSEPAQATTSGPLNATTGTQQQQQQQRSHNHAVNNPWGILTPDNTQHPQALPSFSDFAANLDFSQFDATAPFPNGAPQTPGHDLNSDEFLSALVDGNFSSPSSYPQQAQTFPGTHQPNQSSNLQNPPRRCPPDTALRPNRLFTRNSSNNTPAALLVGQAPTGNLASFDENEVEESLFVSSDDEQPPVTMPVQTRRRASTILSSDHDPEPEDIAAPTSRKRAAPSSAPSRGSAAPKRRRTSQPQGTRTQTAANTLVIDDDPFAEEKQESKKGKQKDEDIIDLAGPNEVPEEVKVPKEDNRVKLSAFQCVICMDDVTALTVTHCAGHLFCSECLHSALNVDATKNKCPICRQKVETKDRNEYTSKTKGFWPLELKLMTASRKGKQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3P9</accession>
    <name>A0AAD9D3P9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371781.1">
        <property type="nucleotide sequence ID" value="XM_060509875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3P9"/>
    <dbReference type="GeneID" id="85393774"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="117" mass="12941" checksum="3FEF2086D58A5FB3" modified="2024-05-29" version="1">MGDDGMGGSLNQRDRLRSWYRSMKVAKQSALLSVSALPENVLAFTVVPRTSSILRNVLANEDGRQSRPWFLVENRRDTTTSSTTHKAQPDLPSRAISIRSTGTDTSNTFPNYQLGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8D8</accession>
    <name>A0AAD8U8D8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357928.1">
        <property type="nucleotide sequence ID" value="XM_060512980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8D8"/>
    <dbReference type="GeneID" id="85396878"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="23866" checksum="7D321443E9AE9E0E" modified="2024-05-29" version="1">MGNFGSSDGQLLKSGKFSDCKVQCEGKTWNCHESILCTRSDYFLKNLGEDWPSGKTGVSEITCFTAEQMDWTISYIYTGEFDFHSAEKNKTILNSAVQLWTLGDYLLVPNICSDVESKFDDLKNRTPKAFYPNPQDWLNAGRVFYVDYQDMDSTHPLKAKFLDLTLGKAWARTHNLQMPEFKILCQEHPNFGNDCMMKLIDDRTHTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8H2</accession>
    <name>A0AAD8U8H2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Membrane bound O-acyl transferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_643163</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000217">
        <property type="protein sequence ID" value="KAK1707125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357973.1">
        <property type="nucleotide sequence ID" value="XM_060509656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8H2"/>
    <dbReference type="GeneID" id="85393555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="226"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1707125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="390" mass="44279" checksum="B229636C9F4DC4AE" modified="2024-05-29" version="1">MPLERADFVGAIWLTTPILVLLGSKIPRHLRWILLIPFVGVCVLVAFAFPFGPDIAKNYTFGTVFYVALVNLNLLVLEDPYLEHRWTQPTSDGKKPQQPFHSLGAWERIRWCFDNAFSTRGIGWNWRTAPLPPAPAPGTSKPAFLRLSMQRILQQYMSHDIAAGLLLWLTHDGKMGVVELDFVPRCIATACWWASSIAVMDIGYHIACMIGVSSGLFWTRIEDVHPVNGPWVECYTLSRFWNRTWHQNFRRGLQIPSRFVARRVVRAPRGSMLSRQTQSSCAFALSGLYHWAAAKMAAPSESFTRTLTFFLLMPNILLLEDLIIQFAQEKLGWRGFWWRIVGLAWTFLALTILGTGFVNDLVAPGLVTAFPALPMSPTYYMLNTMVENRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8S7</accession>
    <name>A0AAD8U8S7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_92086</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359581.1">
        <property type="nucleotide sequence ID" value="XM_060516009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8S7"/>
    <dbReference type="GeneID" id="85399907"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000002">
        <property type="entry name" value="External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.100:FF:000005">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 64 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF50">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="546"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1712965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="700" mass="78008" checksum="3E066BCE83C7A12E" modified="2024-05-29" version="1">MPPTTSALRRIPRAVSHTSPISLLKPTPICRQQVAALAQRRAFISPPPQRSRTTPPTTPLANSFFYAHGLPKGTTVRSVSGAPTPTPTPKQRSRLLRFAYASAAWLGGGIIFVGLGVVGFFIYDASTYKEHPDQNEIEVSELALSPKRGGPKNLPIAEVLIDDLDNEHMKSAKEKPKLVILGGGWGGVALLKELNPDEYHVTVVSPTNYFLFTPMLPSATVGTLELRSLVEPVRRILARVHGHFIRAKAEDVEFSHKLIECSQPDAFGNETRFYVPYDKLVIAVGSTTNPHGVKGLENAHFLKDISDARKVRNQVMHNLEQACLPTTADEERKRLLSFVVSGGGPTGVEFAAELFDMLNEDLTLHFPKLLRNEISVHLIQSRSHILNTYDETLSKYAEEHFARDQVDILTNSRVKEVHPDKITFTQKQPDGSLLTKELPMGFCLWSTGVAQADLCKRLSSKLGPSQTNRHALETDTHLRLNGTPLGDVYAIGDCSTVQNNVADHIITFCRGLAFKHGKDPETLELHFSDWCEVANDVKRRFPQAVGHLKRLDKLFEQFDKDQSGTLGFGELRELLKQIDSKLTSLPATAQRAHQQGQYLAHKFNKMARTSDGLKANMVLDGDIDSVVYKAFEYRHLGSLAYIGNSAVFDWGQGWNFAGGLWAVYMWRSVYFAQSVSLRTRILLAMDWAKRGLFGRDLMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U963</accession>
    <name>A0AAD8U963_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_758652</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000249">
        <property type="protein sequence ID" value="KAK1705038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357539.1">
        <property type="nucleotide sequence ID" value="XM_060515068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U963"/>
    <dbReference type="GeneID" id="85398966"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000060">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23617">
        <property type="entry name" value="EF-hand_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="10">
        <location>
            <begin position="461"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="580"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="194"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="417"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="271"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1705038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="743" mass="80326" checksum="E069F18C00002764" modified="2024-05-29" version="1">MADTAAPTAPAAAPATAAAPLPQGTIVSATSDPSKPSLRYQAGGGASETERTVKTLGDSVIPHLTKIFNVHAGQDDKKWHKEQIASFVKNVQAEETPECLVANTSEAAAGGAAASSPPEELDFNGFLNYMTSSASAITRPVHEEDLSYPLSSYFISSSHNTYLTGNQLYSESSTDAYRNVLVRGCRCIEIDVWDGDDSDNEDGTSVSSSDEEAVAAAAASGQAKPKKEKRSKLAMLKDKMPGSLASRLEKTSLGKKMDERIEKSTSPPTETAITRSAVTAAAPAPATATASAAESITATTTPKETAPGTEQPPLQKTPSPRMFPIEPQVFHGYTLTKEVPFRHVCETIRDYGFHSADTPLIVSLEVHCSAEQQEIMVKIMEDTWAGLLVPTPDVDAPELPRPADLMGKILVKVKYAPPPGGSGVTGAQDEDSEEDGKTTPPVPPPKSKKAAAKPSKIIQALSRLGVYTRGVSFKSLTQPEASMPTHIFSLSEKGVMEVHEKQGDALFHHNRHYLMRAYPSGLRIGSSNLDAAVFWRRGIQIVALNWQNWDEGMMLNEGMFAGTKGYVLKPEGYRCLKTGSTPDPSSPTTPQIIYKTLDLQIDVLAAQNLPLPPGDTRISGFKPYVKVEIHVESPEERLPGAHIKDDGRERESEYKAKTKSNRGVDPDFKGETLQFAGVPGVVEALTFVRFTVRDDEIGRDDLAAWAAVRLDRLRAGYRFVHLMDCEGRLTDGVVLVRVTKQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9S3</accession>
    <name>A0AAD8U9S3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Transfer RNA methyltransferase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRM8</name>
        <name evidence="13" type="ORF">BDZ83DRAFT_588453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10 11">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a complex with TRM82.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9S3"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106143">
        <property type="term" value="C:tRNA (m7G46) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000060">
        <property type="entry name" value="tRNA (guanine-N(7)-)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="128"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="163"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="261"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00060552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1714948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="32776" checksum="6916B0B11380AFA6" modified="2024-05-29" version="1">MSRPEKKNKTTKREEYRNARNQDGVAELPKKKFYRQRAHANPFSDHQLVYPASPDSMNWTQYYPAFAANDETPSTDPTVTGSMTLDASKPKTRSLTKDVEVVDIGCGFGGLTVALSPILPETLILGLEIRTSVTEYVQERIKALRVQNQETGRYQNISCLRANSMKFLPNFFKKAQLSKIFICFPDPHFKARKHKARIVSTTLNSEYAFALRPGGIVYTITDVEPLHQWMVGHFNAHPAFERVPEEEQEADECVKVMASETEESKKVTRNQGQKHIALFRRLEDPPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAG8</accession>
    <name>A0AAD8UAG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_96651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359387.1">
        <property type="nucleotide sequence ID" value="XM_060516035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAG8"/>
    <dbReference type="GeneID" id="85399933"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000374">
        <property type="entry name" value="3-oxoacyl-(Acyl-carrier-protein) reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107">
        <property type="entry name" value="NADPH-DEPENDENT ALDEHYDE REDUCTASE-LIKE PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48107:SF7">
        <property type="entry name" value="RE15974P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1712269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="27365" checksum="C1F5A76C6A8095BC" modified="2024-05-29" version="1">MSDFRGVDLTGKTAIVTGASRGIGAAIAKQLGRRGANVVVNFVTDSSHQRAEDIVKDIQQHGSNAIAIQADVGKLSGVSKLVDATLKFSESGKIEILVHNAALGVDANLDEVTEDLYLTHFDTNVKGPIFLTKAVVPHIARGGRIVFVSSAAARLGVAGQTVYAATKAANEALARVWAKELGQEHGITVNCVNPGPVATDQWNESDDQFRKDMEPLIESTPAAARIGEVDDVAPLVAFLCSSDARWTTGSVLCANGGLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAV4</accession>
    <name>A0AAD8UAV4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_767598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358424.1">
        <property type="nucleotide sequence ID" value="XM_060515290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAV4"/>
    <dbReference type="GeneID" id="85399188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176397" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="132"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="48006" checksum="D0E88AC7C4B8619B" modified="2024-05-29" version="1">MSIRMLLAGLAFGQTLGLKTQVPLFESCAASPLLPDSQLACGKPTILPSGGPPVLDNVARNRTAKPPKKDIWRSDEGWQGPHSCAGAYCAYSRPSFANGRGIVLVSTAYNAEEASHLAALAKESIKGEGDSELFRVVEMPGKGLGVIANQHIRRGQQIMAHPPAVVVHRRFVDDIDLENQYRLLDVAAGKLPRDTRKTFMAQMGQSREHQSTGHKVHDIMHTNSFELGLGIRDGHHFGNYPEVSRYNHDCRPNVAFYIDDSDMRHYTHAIKDIQPGEELTISYVDSLSSRAVRQDRAQRNWGFGCTCQQCSLSEAFIRSSDQRLGKMWQIEQQMSHWNGAKVDEEMIEELISLYRQEQLDQSHGSDAFRLAALNYNSLGMEKEALEYAKLAEEQFMLEKGPRAKQVQDMRDLLRDPKEHYSWRQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB20</accession>
    <name>A0AAD8UB20_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Abscisic acid G-protein coupled receptor-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_644380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000252">
        <property type="protein sequence ID" value="KAK1705014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357516.1">
        <property type="nucleotide sequence ID" value="XM_060509750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB20"/>
    <dbReference type="GeneID" id="85393649"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="205"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="351"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="548" mass="59163" checksum="084E1A8691E61043" modified="2024-05-29" version="1">MPWFWSSASCDDSACAAVDPNAPSTVGLLFSLLPFLLTFAAVAAFANQTIFPKLARVHDAHDGEDHYLPSHAPPSLRQAHAEHGQKSARRRVAAAVFSVTIALATVLGELILSEISDLVSRRAREVGLRVTVPTLLVLLVGVIPFLEIQSVVSGAGWKFQRNNKGRIPRFAWGVQMLVFGGWVFAFWSLGGLVGLDKTATAGGGVLRACLERIGVIGISLMAMLSGFAAVSSPWHTLGAVSERRKRPVTEADVSRKEAGLDATNEMLLTKRHRLQALERKAAEAQSGGSSSSGAGSGGFMGKMLGAVRGMGGGDEAEMRALRLEITGLETMEANLHSSLGVMRSRRAADARAATTIGKVLAVPHYVFSLYCLYRILATTLATLRRAYYPSSSFSSSDPINRFLGLLARHWDPSLDQIAWARQISFLLSGVMLAASANSVLQTFHLFSKWMPGLLYQAQANLALMIGQITAVYVISAALLLRSNLPREMGSAVGDALAGALEPRFVDWWFEGWFLASCGVTGLGVWISRRIGREEWDEFGAEEMGAKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB68</accession>
    <name>A0AAD8UB68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_153980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358371.1">
        <property type="nucleotide sequence ID" value="XM_060501343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB68"/>
    <dbReference type="GeneID" id="85385242"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="27243" checksum="A0DA2790B0ECC4A5" modified="2024-05-29" version="1">MAHSSIFDYSSEGSPGPQSQASISSSYESSDWHEYEQDQAQAIASTSASASTSTFKCSCARKASRLLKKIPKEGIVSFDAVMQLHHSVVEQWRQTTRCRHCNNGNINNANVTCALTTASEKLLSLFEATTHAYTATDYFSQTSPDRLGSVHLFSPKLPTTTVTCTRTQMTLGGFLLQDDEANILAAQIIYKSLVTHHSLLQDFQSTQALNDSDQSFINDGGGLQRIIDRLLRLLGRLQWEQDTIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBC4</accession>
    <name>A0AAD8UBC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_27052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360901.1">
        <property type="nucleotide sequence ID" value="XM_060502050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBC4"/>
    <dbReference type="GeneID" id="85385949"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1717414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="398" mass="43465" checksum="B01930416756B87F" modified="2024-05-29" version="1">MIVRSIVSRHGSRALLAPAVARSCHRAGITTDALVGAMTPETFADLTTSAALGQIPHAAAASLQNDPDAAAKRAEAIEARSKTVPNAYNRFRRQQNLNARVGAAVGRPYVPSQLIENPPHPKDISLELLMASQTHMGHHTSRWNPANAKYIYGVRQGIHIISLETTAAYLRRAARVVEEVAYRGGLILFAGTRKGQMDIVTGAAKLAGGCHLFTKWTPGNITNRDVINQGKEVRIVDEKDITLQGFERLQRTGRPLVPDLIVCLNPRENYTMLYECGLANVPTIGIIDTDANPDWVTYAIPANDDSYRSVAVIAGVLGRAGEAGQKRRLAAAENGESEWTTPLETQRFMKAQGNAWEREIKKWQSTASHAAHNAEEGEEARLLEMLQVDRSKAVDGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC66</accession>
    <name>A0AAD8UC66_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_590863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359069.1">
        <property type="nucleotide sequence ID" value="XM_060506374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC66"/>
    <dbReference type="GeneID" id="85390273"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="101" mass="11752" checksum="1AEACF39D6B4F603" modified="2024-05-29" version="1" fragment="single">MAASPVCSSSPDKYRSQFLSHDEYIELRNSEDKHLHDELASIRCSIDNVKRELKADIKELRDNTQRLEDQTQRLEAEVRQSQAYMRNKGLKNPTLPIRPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH4</accession>
    <name>A0AAD8UCH4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_639148</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359234.1">
        <property type="nucleotide sequence ID" value="XM_060509406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH4"/>
    <dbReference type="GeneID" id="85393305"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF5">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02800)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221926" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="11">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1711910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="28585" checksum="A4B99CD2ECBB5D36" modified="2024-05-29" version="1">MVSAKSVTLFGSMLLGNVMGADNMGPAAFLWPPDREWSADADNTAPCGSTNGPGVRTEFPLVNGKLALVTQDVTRSVHLSVSYENDPKSVSDFETFLGPSEVGSLDLGHTCVTVPSAPSGTAAGSNATYRMLYVSNFDQDESKRETYYACADVTFVDVFATSIPCFNATVSDPDVDVDTTVNVTTTDSGGNTPHTAADFTAAGESKSSGLSKGAIAGAAVGSIAGVSLLALAGFFFWRKKAAKKEAVTEPMQQRWDAEKAVSDTSSVNSRPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCN7</accession>
    <name>A0AAD8UCN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spherulin-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_590740</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359118.1">
        <property type="nucleotide sequence ID" value="XM_060506363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCN7"/>
    <dbReference type="GeneID" id="85390262"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042037104" evidence="6">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="7">
        <location>
            <begin position="60"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1711565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="24955" checksum="3215D4AC6E292522" modified="2024-05-29" version="1">MAVSAPSPTRLSSLLLLCLFAAFIYATDNTLYPDLVRSLRTSPSELDKLDILPEDKDWTFNYFAHEYHTNSPGGVVNANAVTFPATVGNGLTMAWISLGPCAMLPPHYHARASNYVVSVEGTTETYMTLENGARVVKTTLAPGMMTIFPQGSLHTMQNTGCDNATLISALSSEDAGTHNVANGLFDLPPSVVAAAFGGNPLSAKFAQLRRDIPAVGTGAAVGTAECLERCEAIGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCU9</accession>
    <name>A0AAD8UCU9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_638321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359475.1">
        <property type="nucleotide sequence ID" value="XM_060509357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCU9"/>
    <dbReference type="GeneID" id="85393256"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="95" mass="10389" checksum="FD84FC891C409BDE" modified="2024-05-29" version="1">MFLCIAAGMLYAFAPPKEVGLCLVDSFPCCSGTHTSSKYSARGPAYPCPIEADNCTCLTMSGRHSYLQEPDAIDLNVVRNMLQVLFRVANHQRAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD00</accession>
    <name>A0AAD8UD00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359519.1">
        <property type="nucleotide sequence ID" value="XM_060514827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD00"/>
    <dbReference type="GeneID" id="85398725"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944614" evidence="2">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="303" mass="32703" checksum="070A4F221AFCB385" modified="2024-05-29" version="1">MTRHYRHSALGLAAVLALLSATTNLPDLMLVPGVVAVEDLEAEDVPPECAQVCAPIVQLTARCEAQVEAQFGTDKRDLSMRRYRDGLVRDREIREGRERRGDGKKRRRRNLQKMLGRRLSGRQELESEDSSDDEEEPPASLAPGSGLAAVPTLGVGRSASAEDAAKEAAKEAAEAAAKNASRVYQRDHWRMRLRCRTGRSGSGTAGTAGDDFYDYDFLSAGSAAAGVKPSRNNNVTGKLGPRAAFPVIIYLFNLVVNTLTASAGCTTRHPDIYLNNCIPADHSTGISDSFNIAHSAAAIRTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDA3</accession>
    <name>A0AAD8UDA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_590001</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359448.1">
        <property type="nucleotide sequence ID" value="XM_060506289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDA3"/>
    <dbReference type="GeneID" id="85390188"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="38"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="289"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1712591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="44633" checksum="8EC47E6BCB7EA8B6" modified="2024-05-29" version="1">MSSPEKGSEAWKAQDKGPGIITVCWIFTALSTIFVLGRVVVRWKIMRKFHSDDYFVIAGLQVCGYISTSLSTLAVYSGIGKHLELLTLEQQQDVMLWTTAAQCPGIMSFGLPKLAVVSLLTRLMNPEVYHKWFLWWMGIWCQLTLFVTVGLLIGRCTPASSLWDFSIEGTCFSTDVLINFSIYAGTFSAFVDVYLAVYPSIVLYRLQMPIKKKVALSCALGIGAISGVVAIYKTTRLPLLASEDYSYETPDLVVWTVIEGSTIIIASSIPVLHPLLELILKRNPFSSARASRPTAKSSDNNTGSAPSNYRPSRVYGNYEYELGQRKTRSKPRDDLGFTIVEGDSQENIVSREGRSRDQTAASIGSQSSQPDDGRIVRTDVVTVSYDEKGRAGETSASKRWRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDJ5</accession>
    <name>A0AAD8UDJ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_723475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1712982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359598.1">
        <property type="nucleotide sequence ID" value="XM_060512565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDJ5"/>
    <dbReference type="GeneID" id="85396463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041769737" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="46"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1712982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="603" mass="64381" checksum="9501D556880D491C" modified="2024-05-29" version="1">MRLFRTLPLVVAGLLAPCLSGAFPSYKGQDAATTFLDRLLPSLLVVDLGYAKYEGYNNATSGLNIWKGIRYAAPPTGSQRWQPPRLPSSNDTAGAGDGVTAANEFGPICPQNYPAVPGLPFIPGNEDCLFLNVYAPADAKDLPVLVYIHGGGYGYGDGRIDMSEIIGANEGGFVAVVIQYRLGALGFLSSADVKAQGVVNAGLLDQAFALGWVQRFIGLFGGDRGKVTIAGESAGAGSVMYHTLAADGGLGTTLFNNGIAASPYLPFHYTFDAPFPTARYQAFAEKAGCSSSDDVLTCLRGKDSMTLQVASANTTFEQPYGFWAFYPVTDSVYIKSLPTEQMKQKKVNGERLLVGHNANEGPLLTPPNIFSVADLTSWLKLEFPNLSPGQIDEILAANPTKTGSNDTRFETNGLTGLTALDVSQSGTGQQQRANNIYAEATFVCPSYWLSDAFTSPMSSWHYQYSVPFAWHTADIPGYFGPATPNQGPDIVLAFRKIWGNFITGNDPSISNELANGASSGADIGAENGASQWPVWTEEAPKQVNLNQTGGVPYEFTTSWGAQVTQFMAPGQVNDIRVVPADSWEGGRGARCEFWRGLAPSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDW3</accession>
    <name>A0AAD8UDW3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_756755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359766.1">
        <property type="nucleotide sequence ID" value="XM_060514792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDW3"/>
    <dbReference type="GeneID" id="85398690"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF53">
        <property type="entry name" value="BETA-1,4-GLUCOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996006" evidence="3">
        <location>
            <begin position="24"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="66001" checksum="C44B61861EAD768C" modified="2024-05-29" version="1">MRIQAYNLQRMPVLALCLVQVAAQDEFQWPSFRPLEYATPVSAAVETPTHARPYSELSTLLEPRSTKTWDAPGVVPTDQDVEYGNAALSSLWAPIPVLSPPFTTSVSPTPIPSAELIKPPPLPLQPPPGTTGNGTLKFPKAFEWGFAGAALQIEGAIQNEGRGPSIWENRSRGNYSSSGPGSGPPDIAAMNYYLYKQDIARLAAVGVQSYSFSISWSRIVPFGVRGSPINKQGIDHYNDVIDTVLAYGMKPVVTLHHFDTPAYFQSNTSSLSFDHPEFVDGFIYYAQTVLAHYSDRVGTWYTFNEPTIEAAITGAWQPSRFVLEAHAKVVRWYRDAIQGDALWSMKFDLSGTGFALPLDPGNASDVAAAIRRNEYTIGYFARPLFLCENVPQSMIDTVGDRVPSYTDEELELFNGTADFFAFDIYTASYHSEPGGGFAACAADSKHPLYPECTVTTTSRGGGWEANFHGNVDRPAVPAEHVRSILGFLQTTYPAKGGITIAEFGLPAFKASDMSVPHIRSDLAQSEFYVPILNEVLKAINIDGVHVKGLYGWSYLDNWEWGQYDDKYGVQGYNQTTQERFYKRAIFDYAGFVQKHMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE16</accession>
    <name>A0AAD8UE16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_77429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359853.1">
        <property type="nucleotide sequence ID" value="XM_060515417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE16"/>
    <dbReference type="GeneID" id="85399315"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042217283" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13074" checksum="4EF289767DA552A5" modified="2024-05-29" version="1">MPVFLLFRLVLFTYSHYQHFIAIRAWAVEAYFAGVSRRTIEACTSERRGTAGQAAKCQVLQGTMEPRDAEKYDLDRTNRQFPALEDLRMSHYKGQKQACLGCNMRRRVLVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE87</accession>
    <name>A0AAD8UE87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin fusion degradation protein UFD1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_757286</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359120.1">
        <property type="nucleotide sequence ID" value="XM_060514873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE87"/>
    <dbReference type="GeneID" id="85398771"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.10">
        <property type="entry name" value="Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain (AZUL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032353">
        <property type="entry name" value="AZUL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042556">
        <property type="entry name" value="AZUL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056012">
        <property type="entry name" value="DUF7590"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF15">
        <property type="entry name" value="FUSION DEGRADATION PROTEIN (UFD1), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16558">
        <property type="entry name" value="AZUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24503">
        <property type="entry name" value="DUF7590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23580">
        <property type="entry name" value="Znf_XAF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="3">
        <location>
            <begin position="78"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="6">
        <location>
            <begin position="163"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7590" evidence="5">
        <location>
            <begin position="263"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-protein ligase E3A N-terminal zinc-binding" evidence="4">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="720" mass="80672" checksum="D132B7C600DB9B85" modified="2024-05-29" version="1">MENEQPELKWSAPFAVVPPIKSASRDLRGDKILLPQSALEQLLAASPRPPAPSNSTFTSYDPFNPYARQQQQSLYHETSQQLPNPLMFRLVNQKNGNTVYAGIREFSAEEGEIALGPYLMDALGLLPTDFFDDSLPKEPSESTSGMVLNTEPRLMVHAKQLPKGTYVRLRPLEAGYDPDDWKSLLERQLRESYTTLTKETVLSVRGVKGEDFKFLVDKFLPEGDGICVVDTDLEVDIEALNEEQARETMRQIMAKVQPGTSNGSSIGGEIDVWKPINGQVLQGEYIDYELPSWDRIRPLTIELSKLPHPDRIDLFVSPRSARQRARPRDAEHVFGSFNPAEDGIKSITIQPTNVEMETAEQLLISIYYYPLVGNHQVPNPATFQLRARAEAAELSKDVPFDSEHRDSRSSDEDQCKNCLQWIPKRTLVLHQNFCLRNNVACPKCKRVFKKGSEEWESHWHCEHDDAFGDSPASKAKHDAFCHLEVPQEGDPFNPSAETILSGLTAHELADGARTTDCHLCNKIVRMRDMSAHMKHHELDKISRRKPEICRNINCGRTLHGVGSAGAVGAGTAMGQGPGNDLGLCSLCFGPLYVSMHDPEGKALRRRIERRYLSQLMTGCGKKWCGNEWCKSGRINRGLDAKGGSAQAALPLVKPLVQSIPEMKEPMHFCVDEASQRRRRLAEMLASEGVWDFEWCIAACEAGSGDLDKAREWLSNWAPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEX7</accession>
    <name>A0AAD8UEX7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide hydrolase</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_675085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363012.1">
        <property type="nucleotide sequence ID" value="XM_060511145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEX7"/>
    <dbReference type="GeneID" id="85395044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04816">
        <property type="entry name" value="PA_SaNapH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041773452" description="Peptide hydrolase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="126"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="9">
        <location>
            <begin position="245"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="53028" checksum="2B51FD45D5384EA1" modified="2024-05-29" version="1">MKTATALAAALFALRSFATDPLTADKAEADIKTEELERNLWNLNKIARDNGGNRAFGLPGYKASSDYILERVQGRFYKQLDTKVQYFNHTFSQTREISVTGPDGEDVYVVALQYNHPTTLPGGDTAPLIDTPVDDTRGSGCFADQWTGIDATGKLALVKRGVCAISDKLKLAKAAGAVGVILYNQTPGKDIGSATLSAENLGLLVPVGLIPLEDATAWKARLAAGETLEVNLLVDAIWDERETWNIISETKEGDPNNVIVLGAHLDSVQAGPGVNDDGSGTTALLEIAGSFKKYSGFKNKVRFIWWGAEESGLVGSLYYTAQLSEAEADAIRFYWNYDMIGSINPVYNVYLGDNEGDKFGAQPIHDYIAAQGKPAAFGGFGSSSDYVGFLQLGIPSSGIFTGAGAPTDPCYHLACDTLDNINWDALTINAKAAARVAADFANELPADLPRRATTTPARRSRDAIRREFQKWALASEQAEHAKSCSHGEHNVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF97</accession>
    <name>A0AAD8UF97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_443118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361963.1">
        <property type="nucleotide sequence ID" value="XM_060503120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF97"/>
    <dbReference type="GeneID" id="85387019"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="189"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="774" mass="87433" checksum="4CA476C515F93EFC" modified="2024-05-29" version="1">MTSTSKAWDHSVDQRIGHIAEGLHNNPKFSKKEVPGLQALLDDYINDDIDVDYVQFLRRLLQVFKDSETDGAFSKILHKHTDDEQKRIKRFLAGDDPKKIGNGFQMGPSLGCREELARLHEADCVIQVGAQGIKKLKEPIHKLAVMERALLQNTLTKMEDFIEDNKNELQGAGIVVYYKTEFQNWGLTVKNIPALTCVPKTSQEVQLIVKYAKAHNMGVRCSGFRHSWSPVFAENGYVLISLLGLHEVTKLPNITALPLPESAANDLQTISMVSEKPLKNGNYLVRVGTACTNERLRRWCIDNKTVTMPMNVIMVEITLGGSNAPICHGAGRRHQTLSDLVRRIEYVDCNGEPQEVTKPEHLRAASGCFGLMGVVTHITLEMSPMTYAHLKPEKVSVALAVPPPADLDLSKLPATLADPWRKLTEGEKRGYQEIFEDRATNDFYSEWFWFPYSDKVWVNCWNDTTNSAGVVNFPDDAHIFLSFVQTFTMNVLQNTTLLDKLVDQVCFTEAAVTLISRFAMLALPDKEVSTYVPDALHFQRAIQNVRVRDMEVEIPLVAKGGKTFGPGEPVEIDYAPIQRAWWDAILTAYTKENREKCPMRMPLEMRIMGGSNVVMAPQRGNELGTCSIEVLTLHAASDIWVPFAQQVLDKWMALKDPNTQKLLKTRPHWAKEWKEFTVNGRPWLEKMKNEDYKAEIQEFLGVMADIGKEAGWTLEDLKTRFSNKLFDDIFFSSPPQKKASVTNVLQSRSVNKLPQIRATTKEINLESGEDLISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFE3</accession>
    <name>A0AAD8UFE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_589354</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359735.1">
        <property type="nucleotide sequence ID" value="XM_060506229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFE3"/>
    <dbReference type="GeneID" id="85390128"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="26099" checksum="5DF829BF897CFA7E" modified="2024-05-29" version="1">MACAEGFYCIAQRLILDGADVNDQGGWYGNALQAACAEGHESIAQMLLGDGARVNAAGGHYNTALQAACAEGHGLLARKVLDKGADIDTTGGHYGSALQAASLTGRREIVQLLLDKNANPNAGGGSYGSPLAAASFGGHAEIVETLLKAGAEINVNSGSRSALQIACWEGYGDIAKILLEKGADINAHHEFYGDPLQAASYRGSLEIVRMLLDRGADVQSAAGWFGNATHAAMVGFHAEIRQILLSHAIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFV3</accession>
    <name>A0AAD8UFV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363211.1">
        <property type="nucleotide sequence ID" value="XM_060512887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFV3"/>
    <dbReference type="GeneID" id="85396785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="26214" checksum="319DA38C2DFB9AAF" modified="2024-05-29" version="1">MERAAPGSTINPHRRLRRRPGNLSLRVSIRGIPLDAASSVADGGTSESSESFATTGTVISLPGLECYLSQGSMSIECEVDGQFVITPLRPTRTNNNSATSSDAGSLVPSLISRPNHYPSNRSPQESMRGHPRFADSSTLGWELSRRRFGFHGEPSPASLRSRRMEMFHRDSVHVAAAPPIQVFPEVSSVSSSSQRLPVSPITPPPQYSGLIHVAGTGSWTSSPEEQQALEAAADDIVGMWNSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGQ2</accession>
    <name>A0AAD8UGQ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucan 1, 4-alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_632403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361349.1">
        <property type="nucleotide sequence ID" value="XM_060508969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGQ2"/>
    <dbReference type="GeneID" id="85392868"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="819" mass="87748" checksum="31613488D91A4DA0" modified="2024-05-29" version="1" fragment="single">MDDPWGSPWASTDNTNAPSTSPSKTIIEPPPPAFLSTPSNLNLPSSQSAWLDDDAFGNWASPDAGQATNASPWTWGNDATPIEGLTPSYEPRPRRKSSTPRWPRSRSPSPGLRPPITPNTAPHNASPGQPSPDPWANHVSTYTKDEPEPIADLPQIPDVPPLVLEQAQIGLGLTNAPNAFEKEFIAHTPITTQFAEPPAEPSHEYLQFSDTPIFDRFPTTPKHDHDVAHSSASASNSSDDDDEHDERSDARHADSPITSVEDNALQKPTQRKASGKVLELVEMYDGIAKRTTVSPERAPSLRRSVSRGLDIGPGDLPCQGTTKNDLTEEDQGQTESRDTPEPNADESLDKGSKVEEETIKIDKPTLPDHEPFKVDLQHLELLLPDVSLDESVLPEDVPDRVIHDSFVSISERKMWYRLSRHESLRKHNAGDDDNYVRINWTNSTLRQETLKTVRRWIEEDSFGGRAFRGGLARNAGGKSFGWDATTAASPVDLDRVFGRKAKRKASIHRPTHSISGLPSLSAAPILPGSTGSTPAMGQGNDNWEGLATFGWSSGAGDIKPASGTAMQKPQASGIPLPLAFTGFDNAPKSHASLPAFIKPIAPTPSPAPIATSLKEVEGADADADAEDDEWGDMVSPTTAEATDSTSLPKTSWDSFSTNPLAEATSIPPPDPFLTSSHPGADALRTGNNKENDSRNKSGLWDIGNVISSPAPASTISVAAGIPQSQGGPLSPSASANTYTFRPASTVKRPPNISIAATLNDPPDPLLAGITGVSAGGPVETPRTTGFQTPSTAQTPKTSTEGYGFVKQFVRELPDLSYML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH82</accession>
    <name>A0AAD8UH82_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MaoC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_654714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361604.1">
        <property type="nucleotide sequence ID" value="XM_060510742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH82"/>
    <dbReference type="GeneID" id="85394641"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056362">
        <property type="entry name" value="AtuA-like_ferredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010839">
        <property type="entry name" value="AtuA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47585:SF1">
        <property type="entry name" value="DUF1446 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07287">
        <property type="entry name" value="AtuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23544">
        <property type="entry name" value="AtuA_ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyclic terpene utilisation N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="AtuA-like ferredoxin-fold" evidence="4">
        <location>
            <begin position="493"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="3">
        <location>
            <begin position="646"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="800"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1719520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="920" mass="100999" checksum="BD05962F961B3EC3" modified="2024-05-29" version="1">MDPPRRPIRIGNCSGAINDGIDQIYRLAKYGNVDAITADYLAEFNIAWKAIELQTQPELGYEPNFLEQLAWHNGDAARLVAEKGIKIVHDGGALNPRGLADKTHAYFESLGIRDVKVAWVSGDNVTDAVKRGAFGRVMHLDQPGVEFDPHSQGEDLLAANAYTGMAGIVRALELGADIIICGRCTDASPVMGLAAWWHGWKATDCDVLAASLMAGHLIECGPYVTGGNYCGQREVPDLHHAGFPITEIGADGSIVITKPEGSNGLVSVDTCKAQLLYEIQGVYYLNPDVIADIEQATFIQLGKDRVRLLGVRGLLPPSTAKLSICLMGGYQAEISAYATGLDTDFKFEVLKSQVLGQITQSDFTMFSIERYGSSVTDPQSQKLCTTQFRMFAQSRTKEAFEQFKRAIFYNGLQGYCGLHLGMDWRTMEPRPYIRYFPALIPQSRIPLAVGFVGGETQHTIEARQDGGTPPRQPNYDATVPLSKVPLSRTVKRPLGDLVFARSGDKGGNANVGFWVRNASAWPWLQAFMTRRRLIELLGDDWQARYVVERCEFPGLWAVHFVIKGILQEGVSSSSVLDGFAKSLGEFLRARVVGLPVDLVRVEDDRRPRAFESRARSSRPVKNASGRYDNVDFRKAAGYEHPPIKCAYNRRDVLLFANAIGCQKEELHFLYELHPNFAAFPTFPINLAFKQTDQDVFDFIARTVTGHVPGCPPFDAQRSVDGERGIEILRPIPVSSDGLDLEEISKHNANSPIGGAMILEAEQLLVDKKTNKAYTKMTSTAFGIGQGGYNGPRGPTKSVVKAPERAPDAVHIIKTTPEAALLYRLCGDYNPLHADEAFGQRAGFQGSILQGLGTWNMAAHGLLQKLGGSDPSRFKAYGARFKSVVYPGDTLETRMWVVKSGGGVDDVVFETIVKDEGRVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHB7</accession>
    <name>A0AAD8UHB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_755386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361324.1">
        <property type="nucleotide sequence ID" value="XM_060514603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHB7"/>
    <dbReference type="GeneID" id="85398501"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008418">
        <property type="term" value="F:protein-N-terminal asparagine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070773">
        <property type="term" value="F:protein-N-terminal glutamine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07566">
        <property type="entry name" value="ScNTA1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039703">
        <property type="entry name" value="Nta1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11750:SF26">
        <property type="entry name" value="PROTEIN N-TERMINAL AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="682" mass="74747" checksum="C2BFBDB88E2FAB9E" modified="2024-05-29" version="1">MRIGCLQFAPQVGDVDNNLNRADSVLSKANPDDLDLLVLPELAFSGYNFKSLQHISPFLEHSGSGITSLWARTTALKYNCNVVVGYPEKVDVSDNWPTSPEYYNSAIVVNGDGETIANYRKTFLYYTDETWALEGQGFFDGFIPGLGNASMGICMDLNPYKFEAPWHEFEFAFHVLECESNVVIMSMAWMTREDARMFSRMPNEPDMDTLTYWVTRLEPLIRSENGEEVIVIFCNRTGIEDEAVYAGTSAVIGIQDGEVKIYGLLGRGEKELLVIDTNNAPYAKLVHRPEPNHPSVLHGELEKMNPSPASSTPTGSGGSQSSQTNNSQANDTANTPTDSKKNSPGKPPSVVSFKDSVATRRVRPSPQIQIPPLQSSAGALSLDSPSLPTPTAPSPTPLSMRPKLVIPQSPSSQIWQSFSPVPQSTQSTHSVRSVLSNHSVTSNGRAPADSTPYPDSAQPLSGYPRFPERMIYDGQVVIAQGPYSPMTSTGSQSPMSPRYFWRPSDTLLKTPMEPRGWTAAPESPIMKHAPSSTYQNLSLWAQFDPTGRSHSSNTVRTAVTAVTAKKDEPDSRKQKKADSSRRKESQPPKSRSASKSRDEEPAPATNGATQTSSTHDATPARPSSPKSRHASRSRMRDRSDSALAHREQAAAISQHLENISKRAESSQPPYEKTLLDPDRSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIB3</accession>
    <name>A0AAD8UIB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_629776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362249.1">
        <property type="nucleotide sequence ID" value="XM_060508783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIB3"/>
    <dbReference type="GeneID" id="85392682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="663" mass="74807" checksum="BAFE69226A056DFB" modified="2024-05-29" version="1">MPPPKSGQRSMTFTGCWTCKRRKVKCDERSSACGNCEKMKIPCEGYEIKLQWINVSNPFLEQEKPGSSSNGRGRIRIGRDTGPQYRMRDIDSFLASLEEAPTSKGIIQEGPFTLFQANDSTHESGQTHDLKSPDVAISDCSWVTSAHHSSESTRSQKDATASPIYTDCASSSPSFSTAREDGSPNQVGFDVELIRNSEDDQATPEFQLQEEFNSTLGDIAGLLEDSVELLPIQPQTDISYMRLPRRISTSISGDAVIDRLMHHYVENIASLLQPIPHPQNPYRKLYVPAALQAISEWLPKAKITTPTVSSVIFHSLIASSAFHLGNCGPEQTKYLTLGSQHRQLALHCLQSAINPAMATSEYKLLMVAMLSMVTISNFTTGSDADFVVHLQGTKQLRKTRRRWKVISRATRQLNEISDFLYLLTRTVSFSFTPGPWPSEGAEDIDEPIASQAEPDSCFGYMYGITPAIAVDIEETCRLAEYLLWYEGTEEPIPEGLLEACESLGDRLCNWSLDLEDVRQAMNQDAETLEIFQHHANAWHLAAVIYYHRRIQNCHSENHQQLLAEIADHMHAVEDIKTRSKSTKTNFMAPITWPAFVASCDASDRGPWEHWWERIKCYRVANSRTQWKVVQRLWERRDELEQAGVDTFDWIQAFKDFGVALFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIG3</accession>
    <name>A0AAD8UIG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Indole-diterpene biosynthesis protein PaxU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_578499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364561.1">
        <property type="nucleotide sequence ID" value="XM_060505129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIG3"/>
    <dbReference type="GeneID" id="85389028"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008547">
        <property type="entry name" value="DUF829_TMEM53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265:SF40">
        <property type="entry name" value="DUF829-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12265">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05705">
        <property type="entry name" value="DUF829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41863" checksum="BE0753CC8B0FBC09" modified="2024-05-29" version="1">MASNQPTGAAGPLPAMQELSPTTFLYDPPSSVPDPNSPKLVAIFSWMSAQDVHIAKYTSRYMAMYPSASILLVKCPFIHTLSNRISKRQIKPAVPVIRSLADSTPPPASSETGTGQRAPQLLFHVFSNGGATNLAKFLELYADADRAGRLELPPHVTLYDSCPGGFHWMRSYRALSASMPRILAPLAHVFIGWFWLFHVPLGRIGFFGKMWAALRQKALLGSESRRAYLYSKEDEMIYWGDVERHADESAEVGFKVRKERFDGSQHVAHAKLDSSRYWGLVKDVWDEDLVKKKVEPPTPTSKSADAPSEPTPENASENADKTAEPVKTALDSPRTAPEAPKAALEQETTKTAPEPPKPAPPPPGIAPARPKRQPTPPPTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJL0</accession>
    <name>A0AAD8UJL0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361730.1">
        <property type="nucleotide sequence ID" value="XM_060505798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJL0"/>
    <dbReference type="GeneID" id="85389697"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="55" mass="6164" checksum="88A06939EEAEA550" modified="2024-05-29" version="1" fragment="single">VTLNILIIGIIKISFGLGEEICALGIVKVNIRFGTIIFYILLINIPFLLYLKDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJP2</accession>
    <name>A0AAD8UJP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_794270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362539.1">
        <property type="nucleotide sequence ID" value="XM_060515808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJP2"/>
    <dbReference type="GeneID" id="85399706"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041914424" evidence="2">
        <location>
            <begin position="19"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="33842" checksum="7353031574AB67CE" modified="2024-05-29" version="1">MRALAVVTSALLATYVSAQQGAVCFDDLDCLLSGGQNAKCVRAQAGGITGNCAGGKAAGAAGAAAGAGAGAAQPAGQQAAAADPIGSLLGGLTGKKATGKTTGGAAAPAKAKTAGKAKAPVLGARQAAAAPAASAAPAADPIGAVLGTAAGLLKGKGGQPAGAAAPAGSQATDPIGQVLGTAAGVLKGKGAPAAGAAAPAGQQANPLNAVLGAAAGVLKGKGGAQPAAAAPAAGVAAPPPAAAPAAPVPSKPAAAAPALPAASKPAGSTPAAPPAAAPPAGGKPNAPAGGKPSSAPVPPAAAPAAPAAGKPAPPPAAAPAAPAASKPAPPPAAAPPKTPAEGKPAPPPAAAPPPAPAGGKPVPAAPAAPAAPAGKLIRRVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK09</accession>
    <name>A0AAD8UK09_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_578070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364723.1">
        <property type="nucleotide sequence ID" value="XM_060505082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK09"/>
    <dbReference type="GeneID" id="85388981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041947007" description="Cell wall protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="29320" checksum="57558B86DE00F36A" modified="2024-05-29" version="1">MQLSFLLVPLLSITALAKDHNGGGGKNSTEAQCKRFLKGEKLVKIAGNDTLLAEITNNNATKIDFIKKKAAEVQPKLDEAKKNSTLMTSCDQVRAVQQENGQCRFMKRMDKLEKLVANETALNAVTKNNATKADKLKAFAQKGQAKLTDLQKNTTLLSYCSMQTTKGECKQMNKLNKLVALSKNDTALNDKFKGNTTKIEKFKAKAAKQEAKLNAMMNNSTLMGVCQQLKAGKGSSNGGSNNSQNGIDSGAAGVRAAGALSLAAVVSVVVGLMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK41</accession>
    <name>A0AAD8UK41_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364292.1">
        <property type="nucleotide sequence ID" value="XM_060508384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK41"/>
    <dbReference type="GeneID" id="85392283"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042006080" description="Secreted protein" evidence="1">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10644" checksum="57AA661B11C27A9A" modified="2024-05-29" version="1">MGTSPRLACSPAACPRIVPEFRVWVLLLILLLPSSPPATGSLRLVHDHVLRLIDSGPTVQYPPSSLVVECSCLLPSLRIRILSQSTHQHQQTRKSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK47</accession>
    <name>A0AAD8UK47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_626931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363284.1">
        <property type="nucleotide sequence ID" value="XM_060508599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK47"/>
    <dbReference type="GeneID" id="85392498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="284" mass="29200" checksum="F302B2BB8FA3931D" modified="2024-05-29" version="1">MADNQPDAKTPPTSLGGQTGVGTGTPNTLSEATRAQTTPTPSIKATPSSSLPARASSSSSSAPIRQNTPTPSQTPSPTPSAPPPPPPPPPPPSSSARPLTTFIISTTTNATSTPTPSLSDPPPLPSPTSIPGVIPISTPGGGDLIPTPTPSFIPPPPAPVIPETTPLLSLIPTPTPTPTPSGNANSGSGGIASPSQAETSGGSNVKLMPALPIALGSVGGVLIFGLVIGMLYRKGRWPFRSKRNFAQIDELEVERQQELERQNKMKWDPRVTRTYRTQDAGVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKU9</accession>
    <name>A0AAD8UKU9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deoxycytidylate deaminase</fullName>
            <ecNumber evidence="7">3.5.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">dCMP deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_622259</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.12" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364757.1">
        <property type="nucleotide sequence ID" value="XM_060508323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKU9"/>
    <dbReference type="GeneID" id="85392222"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000035">
        <property type="entry name" value="dCMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086:SF18">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="DEOXYCYTIDYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="12">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="13">
        <location>
            <begin position="290"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="33"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="451" mass="49253" checksum="7EC5A019E94969AD" modified="2024-05-29" version="1">MLIGICGGICAGKKSVAQYLIEHHGFRLLRLTDPAATPPRDEAPVSKPVPAPESRPEPERADSQFTNGNNAPGSQLQPSSKNKKKKNKGGAPGSCFNCNEKGHTKAECPHPQWAPEGSIDTAVAISSNADREPKQQQQKPAFSPAPLTILSGQPRTNGVHSHYPNELVFSSADDLLEYVTTRWQSRFVTTDVHNEAILDVLSRRPFFMLISVDAPLTVRHARFRALHNPHCTLESFALASDTHLYDPKQGLQPLISRATVRLLNTSSSIAHLYATLGKLDLANPVRLRPTWDAYFMSLAELASLRSNCMKRRVGAVLVGREKRVISTGYNGTPRGLQNCSDGGCSRCNSGNSSGVGLATCLCIHAEENALLEAGRERIREGAVLYCDTCPCLTCSIKICQVGIDEVVYAHGYSMDTETAAVFRQAGVKLRQYIPPANGLIHLENLEKMELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKV1</accession>
    <name>A0AAD8UKV1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_740926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365203.1">
        <property type="nucleotide sequence ID" value="XM_060513076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKV1"/>
    <dbReference type="GeneID" id="85396974"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="35995" checksum="C3B69E6C44A37F24" modified="2024-05-29" version="1">MHSPPAQQSFLVYMFVANTQFVLSLFGSAVLLLMILLKYVHSRRNLTSWNVLYGNPDMNSSLPSSNNGGSSVKARSVWLGSGSSRGGRSRAYSGAGTNNTYDRWLVIRLSIAFAVLCVFEYTNVIPRIAAASHTIDTADNLEPDLSVRRARSSIRGYVAGVTPSLVAFLVFGTTKTFQCKIHDTFMPKGFSRRNRQKRNLSLSLRDSAAASPPHPPARRPQQVDEFSLTDMSPKFLQSDTYNPRFPSDGSVSPRLPYGNHASPGSSLGTSRGVLPPRAHINHAGQFLSQGVGAPYPRAPSASSSPSLQSKFSVYGRPEARVMAPPRTPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX7</accession>
    <name>A0AAD8UMX7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Family 88 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_357591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364311.1">
        <property type="nucleotide sequence ID" value="XM_060502555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMX7"/>
    <dbReference type="GeneID" id="85386454"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF8">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="375" mass="42911" checksum="AF4DA71866CB80F0" modified="2024-05-29" version="1">MPAGITELHGVKRADIHKQVKQLIHDMVNIKDTTGEFLMTLENGRVIDTKGWGDWEWTHGIGLYGIWKYYELNGDPADLKIIEDWFRDRFEEGHKGKNINTMAVFLTLAYVYEKTGNETYLPWLDSWAEWAYHDLPRTKYGGMQHITYLEVNDQQLWDDTLMMTVLPLAKIGLVLNRPHYVEEAKRQFLLHLQYLFDAPTGLFFHGWTFHEGGHNFARARWARGNSWLTIVIPEFIELLNLTGDDALRSHLINTLEAQCAALVPLQVENGLWRTLLDVPESEGSYVEASATAGFAYGILKAQRKKYIGKEYEAVAVKAINAILENISPEGELLNTSFGTGMGHDLQHYKDIPRTSMPYGQAMAMMALVEFLRVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNE1</accession>
    <name>A0AAD8UNE1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_575345</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366062.1">
        <property type="nucleotide sequence ID" value="XM_060504803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNE1"/>
    <dbReference type="GeneID" id="85388702"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000033">
        <property type="entry name" value="Glucan 1,3-beta-glucosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="18">
        <location>
            <begin position="349"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1726007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="713" mass="80668" checksum="134744E74C939A33" modified="2024-05-29" version="1">MAPGESSRPSSHRPRDSSGKKHHNKKRRSRAEGSRRPATDSGESRDERRSQSLSVDALAKLNQDNVKRQKRREKKERGTGAGRPSRDADADADAERRERRRARREAAYRDAPAERPKRVRREVDTEAVYEKPRREHKNKKKRVVSGAIMEEGRSRGHLRGGGWNSSDHSFEKEYLMEDPPKPVKKRKKLWICLSVSLVLLIIIIVVAVVVSKNNNKSSNTKTTLDDGNKDSVPMKWRGTYLDPWSWDDTTDFNVTFTDQMVGDLPVMGLYTDWDDSKKANDKVPALKDAWGSYGSRPARGVNVGGWLNLEPFITPSLFNYDSRLGIIDEYTLCKHLGTKQTAEVLEKHYSTFVTESTFKEIADAGLDHVRIPFNYWAVEVYDGDPYLFRTSWRYLLRGIEWARKYGLRVNLDVHGLPGSQNGWNHSGRQGAIGWLNGTDGATNAQRSLDMHDRLSKFFAQDRYKNIIAFYGLANEPRNVDLNNADVVSWTAQAYKLVKGNGIGGVVVFGDGFMGLANWQGKLTGYSDLALDVHQYVIFNTDQIVYTHKKKVEYACSGWTEQTEQSMDTSTGYGPTLFAEWSQADTDCAKHLTNVGWGNRWTGTYNTGNATTSILEPRCPTEDSKCDCDTANGDAGGFSSDYKKFLQMFAEAQMHSFEKGWGWWYWTWDTESAPLWSYKKGLAAGILPAKAYDRDFDCSGTVPDFGSLAETYRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNY1</accession>
    <name>A0AAD8UNY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_578533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364594.1">
        <property type="nucleotide sequence ID" value="XM_060505136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNY1"/>
    <dbReference type="GeneID" id="85389035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="57632" checksum="90DF8D1F762F7D96" modified="2024-05-29" version="1">MFFSCRAKQPTPPPPRPHCVSSGCVHKVLKCEAPTKAKRILSIFCKDHACRSRTGEKMCTNPKQPGLSKYCEDHGRCHCQGCSNQRIFADANQDWPYCQNRTFLVTFASLIPHSSLAIILISPSLGHTDTCSSYGCHNKRATNSQMCSFHTPICLIPACGHPRVGDGLYCSSHTCTDKECSSVIDGGSWCRDHRLCKTAGCSSPRVVSPGRTHEEVCWFHLPTSCNATACGAVVSGGVHFCPQHECTYPPCRERKDNGTDASRLYCASHTCHAQTCPQPAADLANPSKPPHRPSFCVAHKCAASPECPHPSKPASRRCALHACLHPSCPAPRADDPLLVSASQFCIGHECRATGCHGAARSNGSYCDAAHACVVPGCPSPRDIGSGGLGVGGPGSVCCASHTAMIARDTSGWSTTIERKSVPTPPSSPLPQTQKQKFPYLSQTEEALGMRFREERERHDQEARLAEETRAWHAVTTAAAARGGSDEVEVVGGVPVPGGFETRGKRHRARRRGSYDSGVAPSPTVSEGTSPSDFTFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNY3</accession>
    <name>A0AAD8UNY3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SDS23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein sds23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_300430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in DNA replication and cell separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SDS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365640.1">
        <property type="nucleotide sequence ID" value="XM_060502249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNY3"/>
    <dbReference type="GeneID" id="85386148"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030071">
        <property type="term" value="P:regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016711">
        <property type="entry name" value="Ssd23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018148">
        <property type="entry name" value="UCP018148_CBS_YBR214w"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="194"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="268"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="451"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR018148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1725585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="53037" checksum="10913215B2052240" modified="2024-05-29" version="1">MDATPTSGAHNDEAIITSPPAVPQRTPSQTSLHKTTHVHAHRQSFAENLRNAPGSPRAQRHPSFTQAAVQDLLNHPPAANKHSNPRFAGRDWRDISVNELVAQDDFRWVTLDTSVEEASMTLVKHSPSNVVLIREDASSKTAVSTFDYNDLNTYLLVVVGLARPDEEQVPLYDEIVNKAQTGDRIALRDIQPLCRKESLVTLPFDETLERAIEVFGSGIHRVLVTNPSGDVIGILTQLKVIEFFWNEGINFPAIDRLYPVLLRDLGIGTQQIVSVNSDSILGDALALMNAEGLTSVAVIDNGHNVVGNISTVDVKHLTNAADAPLLKQSCMHFISVILGERGVEHGRDSFPVFYVNPYSTLAHTVAKLVATQSHRMWVVESASPSPSAPATPLLAPTTSSVLVPGIGSAPQSPLPTQVSHVVPAAAMPGAHLSGRLTGVISLTDILNMFAKSSGLRPSDPGEQRARRRRSSSSSMRPSLDSSRPSLDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP95</accession>
    <name>A0AAD8UP95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_573593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367048.1">
        <property type="nucleotide sequence ID" value="XM_060504629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP95"/>
    <dbReference type="GeneID" id="85388528"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="13"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="422" mass="46626" checksum="41E1B81792BF4FCB" modified="2024-05-29" version="1">MPFKQHGRQYDLVVFGATGYTGTFVAEHITSHLPTNLKWAVAGRSETKLKGLVAECKKQSPDRLQPEIEICGLNHEDLEALAQKTYILITTVGPYAKYGEFAFRACAENGTHYLDVTGETPWTGTMIGKYENAAQETGAMMFPQIGIESAPPDLVTWSLAKQVREKLSAKTGAVTVSIHKLDSAPSGGTLATVLNLFESFTIQQVRDQHKPYALSPVPNNNKVQSQTSLLTKLVGLRNVPSLGLMTTSIAGMTDTPIIQRTWGLLASVPSREKQFYGPNFSFHEYMRAKGYLQGMAIHWGLAFFGLLLATAAPFRKLVKKFVYEPGQGPDKELSKKDKIEYRGIASPDKESKTEFPKAYCRAWYDGSMYYLTAVLLAQAASTLLEEDVDLPGGVFTPSCLGQPFIDRLQGVGFHFEEKILEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPE6</accession>
    <name>A0AAD8UPE6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_576484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365549.1">
        <property type="nucleotide sequence ID" value="XM_060504920.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388819"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="912"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1348"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1610"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="937"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1348"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1383"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1430"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1481"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1491"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1535"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1650"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1660"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1682"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1753"/>
            <end position="1762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1802" mass="202509" checksum="FCCE2F16C9148B33" modified="2024-05-29" version="1">MSEPNKKILEPQKRYNPLIRPTDEDWDTIHGHFKGLLSLPTTRMGQVLEDYFTSHERKLFMPATEPRSLRDCQEDSARRYQSLISNRFKKCHPSLAMKFTMLYFGLPVEPVLSELTRFMKPDFDVDDWDELCTAEVRPPLHFLTAHDQRNFGYDYMRGKEEQYSTIPVAASQMPDATGEGLSLRGGGDDDDAFMADVDYPPDNGVDKSFGPVQTGIVLENEDDDSLGGGPSSEQSAVASETGQPSPESDKAHGWVPLFGFQGRIMFDTDDMSTFQEAARKLLSLRQHEQSDIVLVEFDLKTAKVLRQFDDNIPLNPVSDLAEHLGQATKSASSSAWFVLRRGEEIPSEWEPPKLFFLTTLIKLTHVDDDGRENLSYLKVPDGKSFFGPKQPGYIYPANKPWGSNQYMPFITTAQEVLVGRPDQPGGSHCDLVISRDDEEPEGSSPPCYGGLEIHRELWDSMHPLISKGQAFRVKTRPLANDTVVFYLPGNSNDARTLKNRECLRRTGSGDPYPDALQKVGLMTKSVIMPMEASHYLIWRGVDYFNPLISHPVGAYSPVRWDHRDKDSSKQAQKALSKLIARSVDDKNEPCQFFVIQPVDGAEDPCTIEAVEGLTGQAKFSMEPLSMKVLKSTLEILYTGDEEIVYDAENDSVVMESLFDEDTIGRSWSPASFVLRPDATDSEAAMARRFILAQVVRADVLQDDELDFVKTLAKSTEPNNHWGPRYGEVAQFRKELSLPAIVPPGKLRPVVFHEPKTPPSTPRKSAHSMPREPDQTPRERSYVRQPSIFDMGVWSPAFPINAPPVEAVLRTGVGRVPMVTKNVLTPSEQWELQDKVWSLSKVNLARLAACPYQNCRFTYRQDEDETLLVHLEKTHAEEKCPWCDTQLFKHWSYRQKEEHYRKSHADQLRKVLQLPERPKSHPPQSQKANSERLRNGPSGATKSLPTFTITDQIRPPVGPLPQPGQPAKASDREKGYQYCDRCGRDHKELKSYEDREHHDRVCVPLAEGAGRCTFCKLCGDREWKIEIDATNFAPFDTYPHKCHGTLHENKPHCTKCGFSMKKLSDEKIDRHRKFCGGFYGTLGCFCPYCQRSFVSDGKQEPIDGIKNHITACPKQEGAKPTPWDIYSEVFWKDTDKSVDPLFVGAAETSAALFKQQHRPRASSRYLSHPLIWHDKPGPIPTSDPPSECPAAGCREPLFGLTPSEVLGHFEKKHFEEPLKQCPLCHLSFKRPKEDREKHPELGEWEDRKDQVSHMECHVFQLWDILTGSTRPPAMVNQEPFNPGHSLWDPENESALDRRDKRCPYFDQCGAMVGFMNQLQWNEHLTKAHAIEPLEAQVVRDMDAEIAAAREGRRQQRIREGKNPIPGLAAPKDIRDRELGPVATDETQTGTGPSVQPSGDQENDPESHNVQQEVPGPKNSTARGPESGNAVREGHRGGRPHDHEPVLSPPPTGSKPRTATALENGPHRGEKPPKGPKGPIKNPPKDPEKETTDPNSVKETPQTGGKTPTAKFVPADDMYCSRCLRPTPKSSPNGEPSKQEQIDAHSDPRRSCRIPARQGQVQIDREDKAILPSKVGWITQKEIVKAGGVTKLRKAFVKNNPGLKTTIYPTDNRFTDMRNLWTRDPNHPKNAENWGLRFRPRTDDDSDESEDDGLRNYHPENEEPGDDDEKEEEDEGGEKKVDGGGEDNGEEEEEEVEEEEEEEDNGEGGSGNRAKQKRKPYRGSLTYDPTYRDRGEEDDLSQTSDRELVSESGDDGAGTSGGSSGAKRKRETAGPSGQGSKGSKDKTQERHRKKAKMGASSQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPH2</accession>
    <name>A0AAD8UPH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_616091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366557.1">
        <property type="nucleotide sequence ID" value="XM_060507948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPH2"/>
    <dbReference type="GeneID" id="85391847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc_UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="635" mass="72007" checksum="CB8232E30624E2F8" modified="2024-05-29" version="1">MAVHLQRRLLQDFAELQRNPYPRVALHTRDNDIRRACLVLQPEGWMPMHTTVNFGDRYPLVAPTIKMNTRMVHPNVYDTYICASILNTFEGYTPAYTLRGIAIQMLSFFSSDSLEQEGGNYTEPLEWYRQESLECRQDFKCPHCNFDGTRSKSDLRRARRHALKALSPTPSSSSSNAATIAAASKNYQGCVLAALPDELLLQTLHSLDFADLLSFSRAWPRIADMLRGYDIIRLRELQCYITKTNFRDTKLGVGVMVPKRKRAIESEFDLISLPAFQDLGVRFSVHNVAFEHWLPLPLSRRHWSSVKDYVAPVMHSLAVAISLPSSNSSTVGVLAAFMNDIVVRLNQVDAHTASGGTAYSGTDNVRIPRMSTLRHASEKAIESYFHLFHLLLCLATANSQLVTDANNKIKRFMSGKTSKMSCPNLGHLLVYLLISDIDTTEAMRKAIITEAITRNVVWMLDRRGSNMPELSYLEPDHVSGYRLKRTFEANRTSYRLLMFSELFRRIARPSNDKTLEQIRDELFDRHGAPPPGAALQLSTEVRRLHDIDNFPHFFNEMGIVRHPSAGNFTSVLRDCVKDSMNRGYSVWGLPAPTALALRSRVEPNVGVRANLVVRNPPGPRYMSRITFFPDKARRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ09</accession>
    <name>A0AAD8UQ09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_651036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365864.1">
        <property type="nucleotide sequence ID" value="XM_060510421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ09"/>
    <dbReference type="GeneID" id="85394320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20568">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000005">
        <property type="entry name" value="G2/mitotic-specific cyclin B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="247"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="340"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="344"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="59"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="494" mass="55601" checksum="63F6DB89A11B783A" modified="2024-05-29" version="1">MPVTRPARATRLVSNENDENSGTTRMTRAKAAALSVDELAVPGKALATKKAATNAIPAAQRTKRAALGDVSNVNKPEAGAGKKPVGKVGLVSKAEKPTGITKKSTSTTRSVAPREKKDKAPGSGSGAISKRKVTTKVIKEEKEISLDDSEPMRKKPATESRTKPDQENVKSQTPIESEPVNANKPFVYPKNVTNLDEEDLDDPLMVAEYANEIFEYLKDLECNSIPNPNYMEHQDDLEWKTRGILVDWLIEVHTRFHLLPETLFLAINIIDRFLSEKVVQLDRLQLVGITAMFIASKYEEVLSPHVANFRHVADDGFSEAEILSAERFVLGTLNYDLSYPNPMNFLRRISKADNYDIQCRTIGKYLMEISLLDHRFMAYRPSHVAAGAMYLARLILDRGDWDDTIAFYAGYNEEEIEPVVRLMVDYLARPVVHEAFFKKYASKKFLKASILTRQWAKKSAPHFGIVDVHLSLDQISNKEDEHYPEEEEEEEANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQJ1</accession>
    <name>A0AAD8UQJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP-2 sterol transfer family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_719266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365434.1">
        <property type="nucleotide sequence ID" value="XM_060512160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQJ1"/>
    <dbReference type="SMR" id="A0AAD8UQJ1"/>
    <dbReference type="GeneID" id="85396058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1050.10:FF:000001">
        <property type="entry name" value="Putative Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF25">
        <property type="entry name" value="SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="13442" checksum="4E3BA7A9D22E4009" modified="2024-05-29" version="1">MGLTNDKFPSSAAFDAINDALGSSEPDRKDAIKQGNAIFAFTLKNSAGETDSWHIDLKEKGVVAKGTGEKPTVTLSLSDADFGNLVQGKANAQKLFMSGKLKIKGDVMKATRMEPILKKAQSKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQK4</accession>
    <name>A0AAD8UQK4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_570961</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368221.1">
        <property type="nucleotide sequence ID" value="XM_060504362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQK4"/>
    <dbReference type="GeneID" id="85388261"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053157">
        <property type="entry name" value="Sterol_Uptake_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47784:SF5">
        <property type="entry name" value="STEROL UPTAKE CONTROL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="60022" checksum="F4957153639C4F62" modified="2024-05-29" version="1">MTILSSSGQSDSADAAAGGSTNHIEDKPYHSKRPHKKSRTGCKNCKTRKVKCDEARPTCRNCVLRKANCNYPGPSHSHSDHRPPGSPSGSSAGPFSPARSRSHTPSHRRNSHYAAGGGDDDDDANALVIKEPLYIPAGDRDAIDMKLLWFYTTNTFTSFATQAGRVKRIDDILKVKIPGHAFESPFLMDCLLGTSALQLQHLKQDIAPSRALRYRARAFEGYRKAIEEGKPETFPALIATSLLLTALSSQMFREEGTKDLYIIDWMVVWRGIGLMIDMATPQTLWDSGLAELFMRPPINLDEAAKHIPNSLLFMVSSIQPGDLDYDDISTYYDTLKYLGSLYAELVNGFGPIMTLRVVTWFTFIPKGFVELGREKRPRALVILAHYLMFMKATQNLWWIEGIGDREIAGIVNYLGEGWYEQLATPRLALLLDDRTDIARLILGDPDWESPIDFYNAPTRDPRTELLTWVDDHGKRYKGMPQRVGDLHPADPAPRTLPWERDGFHHDPMMLSPAGRRYAERVLEAIDSGVQDMDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQT3</accession>
    <name>A0AAD8UQT3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_615675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366690.1">
        <property type="nucleotide sequence ID" value="XM_060507914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQT3"/>
    <dbReference type="GeneID" id="85391813"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146048" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="43"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="22978" checksum="5E7CEAC205DF02D4" modified="2024-05-29" version="1">MYLTKALTLALLHTLVSAQTVVTTVTEAPTSPTAEPQWTSDNTFTSAVLNSTNFYRGEHNASSVTWNETLADFATDYLDDMSGDSCDFEHSGGPYGENLAKGYPNTTASVEAWGEERDDYNFKKGEFDEETGHFTQLVWKDTTDVGCGRKLCGDGQWYLVCEYWPRGNVVGQFTEEVQSRESLGVRMSPSITPWLLAIVGSVTARILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR46</accession>
    <name>A0AAD8UR46_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_769427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367978.1">
        <property type="nucleotide sequence ID" value="XM_060515325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR46"/>
    <dbReference type="GeneID" id="85399223"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF210">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="570" mass="61479" checksum="7638E70AD99A24CF" modified="2024-05-29" version="1">MADTYDYIIVGGGTAGLTVAARLSENPQVTVLVLEAGADRSADLNVLAPGLFPAMYGNADYDWDYKTVAQTSANDKVVAQIRGKQLGGSSAMNFMFWTHPSQRDIDNWGALGNDGCQQTSNLLLDYVDPSVHGTTGPIANEFPQLYNPFLKAWPRTLEKLGLGVDGDPRNGVALGGYVNLLNIDKGTRSYAANAYLGPARQRTSLKVVTGALVTKIVLDKTRDEVLVKGVKWSQDGLEKEATVKKEVILAAGSIASPQLLEVSGVGDKELLGSHGIEVFVDNTNVGENLQDHIYVPLGFAVKPDLPTNEDYANTTYFQEQLDLYLHNKTGRLSSAGASSALLSLKQIASTLDLSLPSPKTNLPGLAEQHGITFRDLKSEAIAQELTIEGGISPQYSADTTKLFSAGSPGNFLSIIGVLEHPFSRGTIHIQSADAAVHPIIDPRYLSHPLDIQLLKVIALHLQTVARTQPLSDLLQGEGTVFQPGYHELTIANVEEWIRGSMQSEYHPCGTCAMLPRSKGGVVDERFRVYGVKGLRVADASIFPLIPRANIQSVVYAVAERAADFIKEDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URX3</accession>
    <name>A0AAD8URX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type I polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_698826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365360.1">
        <property type="nucleotide sequence ID" value="XM_060511401.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85395299"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000031">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF45">
        <property type="entry name" value="CONIDIAL PIGMENT POLYKETIDE SYNTHASE ALB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="390"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1304"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1689"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1304"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1486"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1636"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1770"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1770"/>
            <end position="1799"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2114" mass="230029" checksum="6AC174C11ADC509B" modified="2024-05-29" version="1">MGTTSSPECLCEIFLFGDQTARFAPALQELLLNKNSPYLTAFVGRVNFALKKEISSLPVTERQNFPSFVDVGDLVSKFQQDTKNPALESTLVCFYQLCAFIQFYDCQGRSYPRADGTHIVGLCVGSLAAAAVSCSQSLSDLLVAGVDTVRVAFRLGLRVLHTAELFDAASVKTKDFPSWSVAVAESVLPRTSAEDTLRRFIYDTGLASSSAPYISSISHHSLTISGPPLVLDKLAKTLLSSPKDAVSVPIHAPYHAPHLYAETDVDEILAASGPICPFPSRIPVISGASGKVFEALHLPQLLRSCVKDMLTLSLNITNVSNSVASVLSDTNAANKVLRPISSSIATSVLSSLEPSVSRGCRVDSSITKPTLFSLRTVEQPPRVISGRSHHSKIAIVAMSGRFPDAANLDEFWDVLYQGRDVHRQVPEDRFNAESHYDATGRRKNTSKVLNGCWIEKPGQFDAKFFNISPKEAEQSDPGQRLALETAYEALEMAGIVPDRTPSTQRDRVGVFYGMTSDDWREVNSGQNVDTYFIPGGNRAFTPGRLNYFFKFSGPSASIDTACSSSLTAIHMACNSLWRNDCDTAIAGGTNIMTNPDNFAGLDRGHFLSRTGNCNTFDDGADGYCRADGVGTIVLKRLEDAEEDSDPILGVIAGAYTNHSAEAVSITRPHAGAQEYIFSKLLRESGIDPYDISYVEMHGTGTQAGDATEMSSVLKTFAPTGGRGGRSPHQSLHLGSAKANVGHAESASGVVALIKTLLMLQNNTIPPHCGIKTKINHHFPTDLAERNVHIARAATPWNRPAGGSGIRRSFVNNFSAAGGNSALLLEDAPVSLADDRNLTDPRTTHVVAISARSVGSLKRNLDNLKAFVERAQVEGDFGFLTKLSYTTTARRTHHQFRIALSAQTPEQLLSKLAAASQREEVKRMPVTLPSVGFVFSGQGAQYGGMGKEYFTSFSLFRSAIQAYDRIGQSQGLPSILPLITGEADVESSSPVEIQLSLTCLQMALAKLWKSFGIEPSFVLGHSLGHYAALNVAGVLSASDTIYLTGTRAQLLLDKCEAGSHAMLAVRASVLQIRQFLNANIHEVACVNGPREVVISGKVTDINQLAEHLAADNIKATRVQVPFAFHSAQVDPILSDLDAAASRVTFHSPQIPMLCALEASIFLPGDHGSIGPLHMQRHCRETVNFEGALKTAEREGLISTSGSTLWIEIGPHAVCSTFLKASLGQNTMTIPSLRRAEDPWRVLSDGLSNLYNAGLAVDWNEYHRDFAACHQVLRLPSYSWDHKNYWIQYVHDWSLTKGDAPIATQHPITTSPISTPSTPSVQKIVQETLRGQELTLLAESDLASPLLAEIAHGHLVNGVKVCTSSLYADVGLTLGNYILSRHRPDLLGYAANVHHMQVYKPLILKEDASGTPLPTPFYIEVNYRVDTMTASMTIRSSGSHHDGPVAKHVDCELHFENPKDWESEWDRQAYLIKRSIEYLENRATQGLDSTLATGMIYKVFSSLVDYQQDGFKGLREVVLHSEDLEGTAKVRFRGPRGGFYCNPLWIDSCGQTTGFLMNCHQTTPRDYVYVNHGWKSMKLAREFQEDTTYRTYIHMRPVDGTKYAGDLYILDENSTIIGVYGDITFQGLPRRVLNTVLPPPGATPPEALRGHRERPQPSPMHHTSLEAPGDKTVPSRPAVGAMTMPPPPAADDTSPQLRPLLRILSEEIGLSLSDLNDDDLDFADHGVDSLLSLTLTGRMREDLGIDVDSSAFITCPTLGQLKTFLGFTVSETSSSSSGGASGAGSPPTESEPDTSTTLSSDGEQSKIDSDEEEDVRNAPRGHSLLHHFRATSTLLQGNPKRARSTLFLLPDGSGSATSYASLPPISPAGDIAVYGLNCPWLKDATHLVEFGLRGLSELYVSEILRRQPRGPYDLGGWSAGGICAYEVALMLTRAGHRVDRLILIDSPSPIGLEKLPPRLYDFLDAQNVFGSENPHGAAGGGGSKAPEWLLAHFLAFVEALDNYVAVPWEMALRSFKVGKGLENPLPSPPRAYLLWAEDGVCKNPEDPRPEYSDDDPREMRWLLENRTSFGPNGWEALLGGEENTFVDRISGANHFTMLKRGRNSGLVADFLARAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USJ8</accession>
    <name>A0AAD8USJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">L-asparaginase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_614163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367169.1">
        <property type="nucleotide sequence ID" value="XM_060507813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USJ8"/>
    <dbReference type="GeneID" id="85391712"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110:SF1">
        <property type="entry name" value="L-ASPARAGINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="38229" checksum="1116A2377EFC2B73" modified="2024-05-29" version="1">MTKTSLFEDYVVTDRGGVIENRHAVHAAVVDTSGKILYAVGNPSRMTLARSASKPAQALAVLETPGFDKYGFNRADIALMCASHNSEERHVSRAKSMLSKVGALETDLRCGGHPSICPVVDRSWIRSGFSPTEINNNCSGKHAGMLGGAKALGASFEGYHLPSHPIQDKVKQVVEDLSGLSGDEIEWATDGCNLPAPGQPLYSMGRMYAAFAAAADAIEEDGSAQPVRVKHMSDIYNAMATYPDMVGGEGRFCTVLMEAFEGGLIGKVGADGCYTIGIRASESTKELGVEGAVGIAVKIEDGSLEILYAAVPEILDQLQIGTLEMRRKLASFHHLKRTNTMGVETGQVSHAFSVRHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USL3</accession>
    <name>A0AAD8USL3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_611662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367725.1">
        <property type="nucleotide sequence ID" value="XM_060507669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USL3"/>
    <dbReference type="GeneID" id="85391568"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000003">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="365" mass="40818" checksum="4AE97E3EB95E0DE2" modified="2024-05-29" version="1">MEGLFFNVNSGYIEGIVRGYRNGLLTGSNYANLTQCETIDDLKLQLGPAYGDFLGNLPPNPSTSALAAKTTDKLVSEFRYVRANAVGSLAQFMDYLTYGYMIDNVALLITGTLHERDTRELLERCHPLGWFETMPVLCVATNIEELYNSVLIETPLAAYFKGSLSHQDLDELNIEIVRNTLYKNYLEDFHNFVNTHPDMAGSPTAEVMSEILEFEADRRAINITLNSFGTELNKNDRKKLYPSFGKLYPEGTLMLSRAEDFEGVRLAVDGVGDYKSFFEAAGLGGGPSGPGNQGGGSSSDGKSLEDMFYQKEMEISKSAFTQQFTFAIVYAWVRLREQEIRNITWIAECIAQNQKDRIGNYISVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTD1</accession>
    <name>A0AAD8UTD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YL1 nuclear protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_550666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367026.1">
        <property type="nucleotide sequence ID" value="XM_060503486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTD1"/>
    <dbReference type="GeneID" id="85387385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="275"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="36760" checksum="3A44FCDAAE6E4C98" modified="2024-05-29" version="1" fragment="single">PTTVEWLATGREKRSTAGNRMKSMLANEEPDSDLELLFAEDDNDEGFSDVDDAGSDVQMDSSSDDEDDQQQGDDLDGEKELEKQAREKKLASRKRKAQEAIPAKFRKKVRIEQAAAPAPRPKKKSERTSWLPSATDMPIRASLRQTTMLSKEQLHQQMKEREAKRLKQVAIMEKKAQKLEASKKPPMTQAERLAEAALVEKRNAKSLNRWEVAEKAREEERLAKLAALNNRTLKGPVVTYWSGIGEWEHHLKHVGRTQILFGRRMDRLAKPAPRPVCVITAHPARYRDPETGLPYFNAYAYREIQRLRRGEYKWSSLLGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTH9</accession>
    <name>A0AAD8UTH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_238209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366904.1">
        <property type="nucleotide sequence ID" value="XM_060501857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTH9"/>
    <dbReference type="GeneID" id="85385756"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042023658" evidence="2">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="119" mass="13058" checksum="D7A9AB70CCE10C19" modified="2024-05-29" version="1">MCVCVCVCVCVCVCVCACMDMCACLRERIFQCPRHFCPALSDPMQRQFYLALDLESTEGVDTVAVMAGSLRRFSQDPIILLDSSISLRSKVDRGGEGGADKKELAGQGNSSRYGCSVWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTU7</accession>
    <name>A0AAD8UTU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_649481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367679.1">
        <property type="nucleotide sequence ID" value="XM_060510284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTU7"/>
    <dbReference type="GeneID" id="85394183"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="100" mass="10617" checksum="2DC5DF24B2C924E0" modified="2024-05-29" version="1">MIGGAAFSAVGPLVLGHQRDSYSFAASRKTPRMRDAKVGWAKAVTPLAAVGGEVGRQMSACARDDVMKCTADGLCVFTGLAEDWEDMFMGLGDRVQSECK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTV4</accession>
    <name>A0AAD8UTV4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EKC/KEOPS complex subunit BUD32</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="25 26">Atypical Serine/threonine protein kinase BUD32</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">EKC/KEOPS complex subunit bud32</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">BDZ83DRAFT_716798</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="31" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="31">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Chromosome</location>
            <location evidence="4">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368792.1">
        <property type="nucleotide sequence ID" value="XM_060511880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTV4"/>
    <dbReference type="GeneID" id="85395778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000603">
        <property type="entry name" value="EKC/KEOPS complex subunit bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000845">
        <property type="entry name" value="Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06293">
        <property type="entry name" value="Kdo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="22" id="KW-0010">Activator</keyword>
    <keyword evidence="19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17 31" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="20" id="KW-0779">Telomere</keyword>
    <keyword evidence="23" id="KW-0804">Transcription</keyword>
    <keyword evidence="21" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="30">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00019973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00030980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00033194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="KAK1728737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="30366" checksum="BCA967FA245948F4" modified="2024-05-29" version="1">MTTIPPEGAFPLPPLLTHQTSTPPTLITQGAEARLYHTTHLSSDRPAALKYRPPKPYRHPTLDARLTRSRILAEARVLAKCRREGCPVPALYALDEVAGWLMLEWIPGAPVRVRINEWLGERRTTAAIPEGEGETPEGAPPKKDPTGIKNLMRRMGTAIGQMHKIGIVHGDLTTSNMMLRPPKSSDTNDHDDNPLDGQVFIIDFGLASQSTSDEDRAVDLYVLERAFGSTHPRAEAYFQDVLDAYRGSYKQAPVTLKKLEDVRMRGRKRSMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUB4</accession>
    <name>A0AAD8UUB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fasciclin domain family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_749637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367889.1">
        <property type="nucleotide sequence ID" value="XM_060513789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUB4"/>
    <dbReference type="GeneID" id="85397687"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="68866" checksum="B595F3AC3514BB3B" modified="2024-05-29" version="1">MAGANDDDGGEMVFPASQASSHFPLELVSAAVLCSRETKRRDAAVARGRVQVGSREVDEEVLGGGFERGSVVGLSSESEQMGILISMQALAKTLCGNESESDERGKEARVMVVTTQPPAAILPALRDAIRTELVVHGTAEADVMTRLRRCLGRVSVSRVFDLEGLWEALGDLDIPPESPEPRVVSSSPGVRAPYGERLKKDDDKHDAGGEKKDEGTANVAVDVEVSAEDAAISLGMHAASEPEMSQQPERIVLPELKPRPQTTKSTRTEIADSDEDDDEDAISLPSSSSSSLSPPPSTIRSPTPFMAADSPERGADEKEDTEGAADGQDLNDTLEKTPEQVTEELHDEEETESRPTAGDEIPHAILAVAGAAPPASRFPEDDNPKEPALPDIILITHFHSLMTSLFTRRDRQSAHDSLQRLSSHLRYLSRNLETSPLIILLNSTSSSKESTISKPANTQGGLQPPPRPPNGGENGTDSSGKAVDPTLRSIFNPPALNITGYGYGGNQAASRRNKPTFGLVFSQLLDLHLLCTKIPRDKEDAERLYTAAPGGGGGGEDDGTAVKFVWALEVLLDEIGVWEHETGAEAGGRRMALRIMALRKGREQRWGIVDIRGGRVVDAFESVERKKVGEIRVVGGFGGPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV25</accession>
    <name>A0AAD8UV25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_609882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368373.1">
        <property type="nucleotide sequence ID" value="XM_060507560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV25"/>
    <dbReference type="GeneID" id="85391459"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="25146" checksum="E1B287CFA2AA3EB2" modified="2024-05-29" version="1">MLSRELDPSTATQSFESFAIHAMQSKPDHSFKPLSQTTMWHASSAPAVPEGQTCQRPSCPVIGSLPSAKFARRTSPGCRAWKSSYCPQVPEVPRNPFSQWVLEASSRPESLEHEGRDFLRRPMVGAAQRRPVGLRQRIIDGSLPCPELRALLTASLTPGADCQARAPGPVTAGSGPDAAPTWISLRLRAVSGPTYVYSELQMAPNIEPLSTHLWMNIQHRLILDPRNGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X811</accession>
    <name>A0AAD8X811_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_643578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357849.1">
        <property type="nucleotide sequence ID" value="XM_060509685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X811"/>
    <dbReference type="GeneID" id="85393584"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF52">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="38350" checksum="2B34429FC5FC39ED" modified="2024-05-29" version="1">MCKNDFCELSRTMSNDSLAYSSQAEASQAAPKAKHLRLPNGVYAPTLAFFTYSEDIDTIVLEHHVTRLIKAGVAGIVIHSSIGESVHLTREERSIMIRCVADTIYRGYCDRLKNPRAPLIAACGAQSTRGTLQLCRDAAESGASHALITVPSYYASVISNEMIIQHFFDVTDRSPIPLVIDNFPAAASGLRLTLDDILRIAKHPNVVGVNFKYDHMKNLAREAYELFPKGFFVAGGNTNSIRQCQVLGWNGTIAGLADFATYACVGVRELSGRGKLREAEDLQAVIARGNSVVTGLGLVGIKAVVKFWNDYGGTPRKPCYLPPLIEVIKVLKELSELFRAEKEAEASVARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8N7</accession>
    <name>A0AAD8X8N7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_592006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000183">
        <property type="protein sequence ID" value="KAK1709405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358539.1">
        <property type="nucleotide sequence ID" value="XM_060506497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8N7"/>
    <dbReference type="GeneID" id="85390396"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08570">
        <property type="entry name" value="GDPD_YPL206cp_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43805">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43805:SF1">
        <property type="entry name" value="GP-PDE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="3">
        <location>
            <begin position="34"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1709405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="41429" checksum="658CC924C0CF4079" modified="2024-05-29" version="1">MANKSPDTTAHFTSALPLTTKPTRGGDRGGAQLPQAIAHRGFKAQYPENTLLAFRAALDEAGAHALETDLHLSRDGVVVLSHDGNLKRCFGIEDKKINECDWEYLKTLETVREPKQRMPRLEDLLGLLAEEGREGVWVLLDIKTDDPPAELLGRVADVLASTPGPVPWNERIVFGCWNQPYITHVRTILPNYPISLISWSPLYARNFLTPKQPNLSFNMFQKSLVGPVGKLFIRDVKKNRRQLFVWTVNDEEWMEWSIRAGADGVITDDPELFREVCRRWQGKGEGVSTSTSSTPGQQALGEREADADADEKARAARRTGRVRDGTWKRTARLYLEVAGIQVLVAVFTPILMLVARFGVVGPGPKAAKALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8X9</accession>
    <name>A0AAD8X8X9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_767493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000187">
        <property type="protein sequence ID" value="KAK1709123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358462.1">
        <property type="nucleotide sequence ID" value="XM_060515289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8X9"/>
    <dbReference type="GeneID" id="85399187"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1709123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="167" mass="18749" checksum="1320313103A51A1D" modified="2024-05-29" version="1">MPTPTSRSCRWIAVPRASRIPPELQHILSGRADLRRILAKSFPPVCKMPLLNTVESCILRHASWPREMRIRPSGIHNSDRKGVRRQRLHPWQDTDNAKNCSAETEERSHTAVAGEQFSDIPTLGGRSLVEALSVIFDGLLYDGLDFSECCMAKSISDTVTQESRPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X952</accession>
    <name>A0AAD8X952_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_724863</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000241">
        <property type="protein sequence ID" value="KAK1705470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357626.1">
        <property type="nucleotide sequence ID" value="XM_060512702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X952"/>
    <dbReference type="GeneID" id="85396600"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="43"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1705470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="311" mass="34584" checksum="4AD698BACC22BC3C" modified="2024-05-29" version="1">MIPFVIIPRVGSPPTPVNPGDPAALINGSIWPMAAISTVFLALRIYCKGFIVRWVMWLDDWLLIAGWVFLIASQSFLSEMMKLGFARTYGVTPTMSTVLYCADNCHKISLALTKTSFAVTLLRIASGWQKYIIWFLVTTMNIQFVVHIILTWRAVCPRRPGDTTPHLPGSCWSAEDAITLGIFGGLYSAVSDFVLALLPWKIVLGLQMKKHEKVGVGMAMSMGIFRPSEYPSGAYIRSNNLSKFQNRGISATCSLSNTDRDKRDNDSDQEILGGIMRTTEVSVNSIDYDVQGRRSGKKTPREEHGIELANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9U9</accession>
    <name>A0AAD8X9U9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate kinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_592363</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358421.1">
        <property type="nucleotide sequence ID" value="XM_060506528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9U9"/>
    <dbReference type="GeneID" id="85390427"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1708903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="191" mass="21321" checksum="327620865BF192CC" modified="2024-05-29" version="1">MPVVISILGRPGSEKGTQCRLLSQKFRLSHISIGDVLREEMERGEESPHADIIRANMLAGKIGPIEITMAILKNRITKLMEGGTQVFILDGFPRSIEQSTHFQTLMGPIKSLLVLQCSPETSFHRLLPRGRFDDQTQAIRNRLLTFETTTSLVVDDFRKHKKLTVVDAEPSVAKIHEGLVTIVSSVAELLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAK8</accession>
    <name>A0AAD8XAK8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000248">
        <property type="protein sequence ID" value="KAK1705164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357548.1">
        <property type="nucleotide sequence ID" value="XM_060509746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAK8"/>
    <dbReference type="GeneID" id="85393645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="221"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="427" mass="48948" checksum="CE471E837B4DEB32" modified="2024-05-29" version="1">MAWWHDLSNELKNQIWGHLLKCGSEENHSLAPYASISSEWQKIIEPFVFEEIYISLHSQKSTSSHRKVLQARSILTKPRQKVLKRLRVRIDYDATKTSKNYRRAFAEVIASLFDLLQTWKTEDAKIGLEIVEVRPCGPPLLTYGGELLRQRKWSIGCVWSLRIVKPQSYISRSTGPELADLILTGLAPGLDTLDYNYEIGCRPGHKHKLCLVTDWQIAPVEVKSLTIRESCDQSNLNTQHDWIEYIRTHQGIPEQLYQQSRGLENLCVSFAIDATDFFSHMMDQPKNEGPPPQHSVAGPDWPELQLISLTSHSIWDKAPEMTNKLLLSAARAACRMPKLKVMELWNAREQYIISAGCFRYSIKKDGTPTFVWESTWDFEVEEATKAAWIDAAKSHSSHDLIFEVRKIAAELPWPFSPAWAHAKAFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB00</accession>
    <name>A0AAD8XB00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">S-2-hydroxy-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_723434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359681.1">
        <property type="nucleotide sequence ID" value="XM_060512560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB00"/>
    <dbReference type="GeneID" id="85396458"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF140">
        <property type="entry name" value="FMN HYDROXY ACID DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042062234" evidence="6">
        <location>
            <begin position="17"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="7">
        <location>
            <begin position="43"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="313"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="336"/>
            <end position="337"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="43305" checksum="7D3F412692CE9E32" modified="2024-05-29" version="1">MKSFVIATQLLAIAMAGEPWLNEVDTGFETYLDSTNYTKGSLPLLKDIRAIPDFDWAARQHLDNQKYSFYRTGTAGEYSYRHNLDVWQKVQLRSKHLSDVTKLNETMATTILGYNFSAPLFIAPAARAVYGDPDAELNLVRAAGNENILYIPSMYASKSIEEIATGKVNGTLNGPQVIFQQIYTNANLSVTWENIRRAERTGAKAIVWTIDAPGDSVRHRAARYDTTNANSVSSALTWDIYDQMKNQTSLPIILKGITTAEEALLAVEKGAKAIYISNHGGRQLDHTPGPLEIAYEIYRNAPEVFKKVDVIADSGVRYGNDVLKLLALGVKAVGMGRPFMYANCYGLPGVTKAINIMKTEIVRDGAQMGATDVHNISTSFLEQNVYLFDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBJ6</accession>
    <name>A0AAD8XBJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361222.1">
        <property type="nucleotide sequence ID" value="XM_060512466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBJ6"/>
    <dbReference type="GeneID" id="85396364"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="35372" checksum="F83B49572D90D059" modified="2024-05-29" version="1">MPPRLPQQAARALRRLATTSTPITRSFTTTTSFLAAPAAASLRLPADYVPTTKPPSARPPETRKSQLIRTYTSLLRTTPLILFFQHSNLTADEWSAVRRELNSALVAATPAGTNSPLDGREVHLQVLRTRMFNVALKLAEFYDPEVAKAKAGTRTGPRGPLVHDLSMAAYEAMKDFEVPEDSAYAQISPLLCGPTAALVFPAVSPAHLAAALKILAPSPGKFAAPPRKKNPGYYEPLCQSALQKLLLVGGRVEGDVFDVDGVKWVGGIEGGLDGLRAQLVHMLQSAGLGLTTALEGGSKSLWLALEGRRTQLEDEGKPKESASAEESKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC34</accession>
    <name>A0AAD8XC34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_757250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359138.1">
        <property type="nucleotide sequence ID" value="XM_060514871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC34"/>
    <dbReference type="GeneID" id="85398769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051786">
        <property type="entry name" value="ASN_synthetase/amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43284:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43284">
        <property type="entry name" value="ASPARAGINE SYNTHETASE (GLUTAMINE-HYDROLYZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="722" mass="82029" checksum="9E2BFC44AF3234C1" modified="2024-05-29" version="1">MCGITATIKLRRTATLAKRNRNTIVHEHSHNGSPTRQALHNRLAQSLASIAHRGPDAEGIWISDDGAIGLGHRRLAINDLTSDGVQPLHSDDGKIHAVVNGEIYDHDAIRERCIQDHGYQFKGHCDSEVLIALYKIYGAPGFFEHLRGEFSFVIFDERDGRVITARDRFGIKPMYWTVVGNGSEQQLLLTSEVKGFLPLGWEPEWNVSGLITGLSLQAEHTVYKNVCKLNPGSWMEIAESGEIKHHQYWDPEYKDKREIESRNLDDIILEVRERIVEAVRLRLRADVPVGIYLSGGIDSSVVAGIVTKLVREEGVMLGNQDATKRISCFSIQFPENSGFNEADIAQRTADWLGVQILKKDMNEEELAKNFVECVYHTEHHHFDLNFVGKFCLSTLPRQYGVPVVLTGEGADEHFAGYPFLMPDFLLEPDYAWPDSALANNNQVREAMQREMADDLKKMFTRVGMFDHEWESTAPRSRHLGIGNNALKWQPHSDMFAPWVQDSYGRKNMRVSVAETMSPEVRKNMDEKWHTLHSSLYYYTRGALPNMILTCLGDRTEMAHSIEARPPFLDHHLAEYVNGLPPSLKIAYNQPEGDTDGTGSSLWWKNFSAARQALSEKWILKEAGKPFITQELYDRRKHPYSAPVKWPRKGPIHQLFRKLITESSVSNLGFLEWQDVKSWLEHGFGDDSDPNAFRKLVITGSWVVLSQRFGVKRADRVAEPSCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCH6</accession>
    <name>A0AAD8XCH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">G protein-coupled glucose receptor regulating Gpa2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_582581</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362709.1">
        <property type="nucleotide sequence ID" value="XM_060505566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCH6"/>
    <dbReference type="GeneID" id="85389465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="527"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="542" mass="59606" checksum="B0EF92A05FA00D11" modified="2024-05-29" version="1">MNESEDIVDHYDSDSSPYSVRPLPPVLRHGLAAVATMGFLSFFTSLGLLTFLTYKLIQWQNGPPTPKKEDLIIKVESPKPTDAAFIIPSNWMAATEEETTKKQKETWWQRAINEPPNQFLVLIFNLLLADIQQALAFLLNVEWLTRNAIEVGTGTCWTQGWFVSTGDLASSVFITGIAIHTYMSIVSTKKIPTWAFHTAIVMMWAFVYGTGILGVIITENGKSEGGLYVRAGAWCWINSKYQDVRLTLHYLWIFISLILTTFIYFIIFLHLQKLARQSGGVITCCGHPRTAPSLSNCSGSSSGTTSSCDNHSTMSSNFWRPMCFTTILRRLPDIPDYARQHTFLLYPLVYVVCTIPLAAGRLASMTGHDVSLGYFCFAGAMIACNGWMDVVLYSSTRRSIVFSCEGPPSQEVGLETFSFMCGTPPKFGNTTIVMGGPTSEQKRLRRYNKWCERAARKGPKSGGLKALKVDGIESTESMKGSMKGFGMGEGSVMGMAIQCETTTTVSVEVNTLAPPARPKLAARKLSDASNSSAGSSTTLGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD87</accession>
    <name>A0AAD8XD87_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Wac domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362977.1">
        <property type="nucleotide sequence ID" value="XM_060512890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD87"/>
    <dbReference type="GeneID" id="85396788"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="38261" checksum="2F2F9082EB454196" modified="2024-05-29" version="1">MVISTTTLTTVTMAASPVRSFSADKHRPQCVSHDEYIELRNAEDKHLNAELASIRCSVDDVKRELKADIKVLRDDVTTQIQYLEAEIRRSQAFTRNNALKNPTLPIRPVVVYRPGYGILEPEPSRFPRNANEFYSLRDPQTDRHRSMLAYLAVFYDVQLRSAGHLPEEESNSDDSDDDEIILEHPDLVVEKLEDILGLNEDKITKFKERALQMASRAPSKPIKRSQISWLEDGPIPDPRRQRLELRITAGEEPYFYDPERPKSVSSEGLTNAHVGWGTRSTPSSQRARLQWSPKLARLSEPSKPEPERPKSASKSTEAESTDTDNDTHVFTNSPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDD9</accession>
    <name>A0AAD8XDD9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_754624</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362201.1">
        <property type="nucleotide sequence ID" value="XM_060514501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDD9"/>
    <dbReference type="GeneID" id="85398399"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000474">
        <property type="entry name" value="Sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="119"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1721405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="627" mass="70902" checksum="DF64F700D4E1446A" modified="2024-05-29" version="1">MADKIHPDGEKVADVSGHHEERGTHQPDPVELSRNIEAKIKNPLEGIPYNQLMRDVEAFCTEYGLQEEIAVFRKGALVAQDPEGYETITGTEALDEAEITALREEVTHKWRLPKKLYLTIITCSIGAAVQGWDQTGTNGANIFFPEEYGIASSSTRDRLILGLVNAGPYIGSALCGCWLSDPLNHYFGRRGVIFFSAHFCIWPLIGSAFSHNWQQQLANRLLMGIGMGAKASTVPIYAAENSPPSIRGALVMSWQMWTAFGIALGTAFNLAVYYAKYNWRLMLGAPFLPAVPLLCLIYLCPESPRWLMKKGRYHDAWKSMIQLRHNNIQCARDMYAIHAQLQLESQVLGKSNYASRFMELFTIPRVRRANLVAFTVMIAQQMCGINIIAFYSTTIFKDANMGDFQALLGSFGFGMVNWLFAFPAFWTIDTFGRRSLLLFTFPQMTWTLLAAGLCTLIAPGVTRTALVSLFVYLFGAFYSPGEGPVPFTYSAEVYPLSHREMGMGFAVATCLFWAAILGMTFPFILDRLHVVGAFGLYAGFNVVAFFMILFWVPETKQRTLEELDWVFALPTARFAHYQVTKAIPYFFKRWVFFDRNAKLEPLYTFQQHQREQRAERVPSSDEEKKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDP6</accession>
    <name>A0AAD8XDP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ceramide glucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glucosylceramide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">UDP-glucose ceramide glucosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">UDP-glucose:N-acylsphingosine D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_73962</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.80" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360010.1">
        <property type="nucleotide sequence ID" value="XM_060513045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDP6"/>
    <dbReference type="GeneID" id="85396943"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008120">
        <property type="term" value="F:ceramide glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006679">
        <property type="term" value="P:glucosylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025993">
        <property type="entry name" value="Ceramide_glucosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12726:SF0">
        <property type="entry name" value="CERAMIDE GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13506">
        <property type="entry name" value="Glyco_transf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1714548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="534" mass="59120" checksum="686E5CBE4FB6717F" modified="2024-05-29" version="1">MADWSTVAQAIAIVCAGWSTFVYAVQSIGIVRIFLSYSSRLRPAVSPSLRQEDVPHITIIRPVKGLEHGLYDCIASSFRQDYPRDKLTIHLCVAEKSDPAYPVLVKLVQDFPGFDARVLVEEEDPLLHGTDGHIDNLGPNPKIRNISRAYQEAKGDIIWVMDCNIWVAKGVAGRMVDKLLGYGPGGIKVTPYKFVHLLPIVVDTVSRGDISAETQTLLSSTSDSSSSQNIIGKGQSVSFLEYAKSQGGGRLDEMFMATSHAKFYSAINTVGVAPCAVGKSNMFRKSHLDTVTDPAQNPILPNKNLPKGINYFSEYICEDHLIGDLLWKSSLPGMKNHGLVMGDLAVQPMAGMSVHAYFARRARWLRARKWTVLAATLVEPGVESLTCCGYFAFAVTTLPWFHNTFGTSQTWGAFVLYWTVFTTIWMACDWFTYNRLHAGYTVEVDKNTPKFARGTATPGGAPPRSFLEWLPAWLGREFLALPIWVWAVFCGSTVNWRGRTFNVRSDMSVVEVGSQSSAPSQEAGQRSRSKDRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDQ6</accession>
    <name>A0AAD8XDQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_779880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364044.1">
        <property type="nucleotide sequence ID" value="XM_060515524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDQ6"/>
    <dbReference type="GeneID" id="85399422"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="447" mass="50370" checksum="56CC3B3E5FB1405C" modified="2024-05-29" version="1" fragment="single">PHPIHLLHNSDNYFGIHSSLSQVNLYPSIQSRIPSVSKMAATRTYFARYPHVWHDRSTRPRLTTMSLETIEESLGEVSEAPAPNEVKNMLQSASRAEAITKALFEQVYAPNKPGEKEKGPSTTWTPTTAGCIDCNTSPSPSHNHNNNIGWTSFEDITLDARTLAKYGIRSPRVKSRRSRFHYAYHEEEPLTRNEPWVKRFSYLEDGIEASRRFQRREDMVVDLDNVDVNGLPVEGEIEELVLPPPVLPLPQTPAPVVAPRLEEEFKQWPMDVSTATNEGEDESEVECEITSEDHLCLFCPSVIESERDEDSEYSEADEQIRRELDAVNWNFEKWALGDSDSDADGEELRRELDAVNWDFEKWAFGDYSSDTDSEESPTSPAAAPDTPAERCRGVVAGVEMEGREQVEEEEEEEEESLLSEVLVANLVGISISLLLMSIVFGLLPGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDS8</accession>
    <name>A0AAD8XDS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhoD-like phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_416927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362651.1">
        <property type="nucleotide sequence ID" value="XM_060502958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDS8"/>
    <dbReference type="GeneID" id="85386857"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032093">
        <property type="entry name" value="PhoD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052900">
        <property type="entry name" value="Phospholipid_Metab_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43606:SF7">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16655">
        <property type="entry name" value="PhoD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042020861" evidence="1">
        <location>
            <begin position="18"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipase D N-terminal" evidence="3">
        <location>
            <begin position="61"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="192"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="627" mass="70036" checksum="4842FB975636E67C" modified="2024-05-29" version="1">MVQPIFAVLALATTASAAFTGNLNYLSPSKHHASLGVSINKVAKRTYANSQWDPAKLNFTHGVASGDPYEDSVILWTRAAPTADNDKSNLTVSGYVPLYDHSTEDYVKKSDSPVCVDWKISTSKTLDAVIDSGTAYTSSDVDYTVKVEAKRLAPFTVYYYQFGICNSNKTSPIGRTKTIPSKNSRVETPIKLAVYSCSNYPFGFFNAYGNPVRKDSVDYVIHLGDYIYEYGNGEYGWGNSIGRIPLPDRQIFTLYDYRKRIATYRTDLDLVASHQSFPWIPVWDDHEVSDNTWRDGASELNNTEDSFIADGGVSVDQRKMNAVRAYFEWMPIRQVDMDDNLRIWREFNFGNLFDLVMLDTRQYDRAITDVYTNTDYIHAISNDASRSLMGPRQEAWFYKTLRQSSTRGATWRVIGNQIIFSRMNESLALGAENPMNYDQWDGYQANRNRTFQVLYEQNVGNNIFLAGDSHASWVSDLVWLGEHEYDPKTGSGSVGVEFAGSAVSSPCPAGQNISLAAANAGSAWLTAANRELQWQDLFYRGYYELSIDYDAVNASFFGIPTTRIKQGYEISLANFTVLAGENKLHRLNGTAAIGGIAESGSLKNGRVVQTNLTHDTGSGAYLKYNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDX5</accession>
    <name>A0AAD8XDX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_623860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364254.1">
        <property type="nucleotide sequence ID" value="XM_060508413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDX5"/>
    <dbReference type="GeneID" id="85392312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="606"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="620"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="881" mass="97222" checksum="833513B05EA7EE2B" modified="2024-05-29" version="1">MDPLSVTASIITLIEASGILTKSLHGFIHGLKTVDARVTRLCEELKNLTNLLEAVEGALKDCRSYDLAKVEEDLLQQSDIALADCQATLNDLKMLIEKVKKAAGSRALGWKIKAMFDLSIHGNELVAFQEKIHKSNGALQTIFHTITVSLSLKSKMSHTLIMDELFRLRQSIDRAHEISAKPSEVFTHSFSRLSDARLSRNLKALAKAADGFYSTASSSAGTSRGDRSERTWKPSSSAGFSGPGHLSSFRRERIERFIIEGQTRNGSMTPQLLPQVNTSFHSQSPPETCFSAVKSNPPAPGDDDDLKSLEVVAGGDDKAEEEDDDADDEAAFSREYILCIRQIAIESIKARDFTKAGDLLEKALARCEKATADNGEYCQSSYISMRSLKVQLAICYFFQGNWKLAEPVVTGLASSKSSRDSVVCNLLHALALAYLSEYSFDIALDTCKQALRGHARLSKLRKTDVIMQDLNNSLGLLATTYDMTSDYLSAEVFRRRLSPGFKYQHPANVAEFLQNHSDFLTAALGPYTLDPACVVLPDSPIGQPSEQDATTSSPSEQEVSQVRWDGWGTINHLPSNLRLNMANHRRLEVDTSKIVVARSRSCTIEGHTVEESSPTETILTSPATTASSPNTSPESSPVRGRIARSFSAMGLNRSIARAEPGFGTVSELSLPCDSRRQSTRDTRQPLRSNQETWSVIETDHPTTLPVARHIERWKWIRGWRIPQSDGVLDERTRPAKLQRRSATRVPGRSLTVGEWFTPAKWFRTGQTVLRQASSYHRVVVAAEPRRMPAGPGFPELNGNAVSELGITSPTPELGHYLPSPVSATPQRVHFYVPQAQDRLDITAHMEVCELPSDISMSGALTSLEANTRQTRSQMSLDQFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XED5</accession>
    <name>A0AAD8XED5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_543483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363296.1">
        <property type="nucleotide sequence ID" value="XM_060503421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XED5"/>
    <dbReference type="GeneID" id="85387320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="66720" checksum="956A76C421648379" modified="2024-05-29" version="1" fragment="single">TRPAARGTAFYQRKRAVRACQVCRARRTKCDNLKPSCSFCLKVGATCIQSPVDLSSFDPASLKILERLDDLEEMMRSVTVDGLPSNKTRVVEAPVEHRVIEAPPVGPLIQMGMILPPRPEHVMSWAIFEEISNSVDAGDMALHVDHISIAANSPMSLIGALDLEPRRINDLLDSFFSYVHVKNPILDETATRKMVSHTVLEGINWSAESCLSLLICALGSLATPFGPSQETMLGSAAHSDAQAFFQAAQKRLGILLSSDDIIAAQCLFLSGVYMMCVFQPVKAWRYFVQALASCQQFSFLTPEAQQRYHRNVESGDESRNYSIDTLQQAVYWSSWKSEREMRGDLYLPDFSLSDQELAFYPPFFPTPPAPRAEVEAATDPRLARERTSWYFYLAEISLRRLASRISAEMVGLQKEHPTRQAYLAAMAAAVPQYEEQAQEWISSLPPSLSFAEPPEEDDVCRFVLRGHAVNLYEVIYWPFTAAFLDAFGANPEFAGEVLTPSVELFAQKGLENHAYRLAINHLGYRHRHHGTLPMMRSCSRSALVLVAAALLTQSSGSEGGHSLPNGWYGAVGEVVDLLAFWECETREMELVRRVLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEH3</accession>
    <name>A0AAD8XEH3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SUR7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_652353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364327.1">
        <property type="nucleotide sequence ID" value="XM_060510519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEH3"/>
    <dbReference type="GeneID" id="85394418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032185">
        <property type="term" value="P:septin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36414:SF1">
        <property type="entry name" value="PROTEIN SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="248" mass="26932" checksum="EC4394C5B4807EF8" modified="2024-05-29" version="1">MVKHAPLGTAAIVFLSGSIVLLLFVILSAVRDAAPLNNTYFLAADTTGITGARNGLTRWNYFYYCNDQNAECWGAWPAPAFGWAWGRDAANVPAGLSGSHGGGTTSTEYFYMWRFGWVMYLIALFFMALAWFASFLACCGRLGAAVAGLVSASALFFLTVAAALMTATFVKARNAFQAEGREAHIGTYAFGFTWGAWAALLIATLLFCIGIRGDKGYSGGSRFSRKRSTRSRQSFDVNSSRRVKEDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XER2</accession>
    <name>A0AAD8XER2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_721717</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362078.1">
        <property type="nucleotide sequence ID" value="XM_060512406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XER2"/>
    <dbReference type="GeneID" id="85396304"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="476" mass="49440" checksum="638047E96E4CD60C" modified="2024-05-29" version="1">MLEADEVGEEVNVDDEDMPMDSDDENEEINLQNDSVAYFDAHKDSVFAIAQHPVHPTLIATGGSEGDADDAPGKGYLLSTAAAASRPVLPASFSGDAAQNQSTELQFIYPIDGHTDSINALAFTLPKGDFLVSGGMDGKLRVHALRVNSPTAEAASVQIKFIAEAQEVPEINWIAACPSPKYPNTIAIGASDNSVWVYTIDIAAGGGNPANCLQLVQTYWLHQAPVTAGAWTPDGNFLCTVSEDASLYVWDVWGEAAAAGLVESNGQTTVSLTAEDQRFVVEGGLYSVAVDPKGTLVAVGGAGGAIRIVSLPRLASSAQAGKGGKSKSASDVVGGGQILAALQTASDSIEALSFTTAAGGPGQISTLLAAGSVDGSVTVFDAGRRFAVRRSLVGAHEEFSVVKVEFVKNSWLLTTCGMDGVVRRWDLRAQDGGLVKEWKGHRGDGEGGGVLGFVQGETGERIVTAGDDGVVLVFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGH9</accession>
    <name>A0AAD8XGH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2OG-Fe(II) oxygenase family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_614151</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367164.1">
        <property type="nucleotide sequence ID" value="XM_060507811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGH9"/>
    <dbReference type="GeneID" id="85391710"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF242">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="76"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="36506" checksum="70EBD773BFBC6D35" modified="2024-05-29" version="1">MSAITKVLGLSAYTALVAISIPYIQQHNIPSRLQTSLNRILSPPTDGASSEPEILTAEPYICRSQNYTTQIVSLDPLVIYIHNFLSEADITSLLEAGEPAFKPSYVVKNGRTQGTPDRTSWSAGLPADDVAVQCVLARAEGFLGTMMAPGRDEIGPPQLVRYTQGQRFNVHHDWYDDFQPDVRTGRKRKWNRVASFFAILEDECTGGETWFPKIEAVTPQHRREDGEGTMWRKHDDGGIAFKPVRGNAVFWVNLHGNGTGDGRVVHAGLPVGDGLKTAMNIWPRRYLGPEAWGKGEEPEDEGVRVLGAEKVKVEEKEEELVVDDAEADPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGM6</accession>
    <name>A0AAD8XGM6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TAP-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_414926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362710.1">
        <property type="nucleotide sequence ID" value="XM_060502940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGM6"/>
    <dbReference type="GeneID" id="85386839"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041904493" evidence="3">
        <location>
            <begin position="18"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="4">
        <location>
            <begin position="455"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="590" mass="64185" checksum="C0967BED20C8A416" modified="2024-05-29" version="1">MVSSLLLVGSLFGLTQAVSLPLTTRSTNSTKAFSWVDTKPTRDLQYHDCGDGFQCARLEVPLDWSNPTKNSTASIGILKLPATVPNDDPSFAGSILINPGGPSGSGTGFAYSFGPILQKVLGQDRNYEIIGFDPRGVNTSTPRADCFKGDQFARRLSQERDSVLPPIDDALGYHWADANAQSALCEENGVDSIWGHMNTASVARDMVGIIDRIDDLRWKESGKAKPKDAEAARLQYIGISYGTYLGNTFASMFPERIGRIWIDAVVDGDDWAAGTFRNNINDVEKIVDQFYAVCFESKEDCPLFQSSDKSGSDVKARVADFLNEMDTNPVYFAYNDRPAVLTSPIIRQAIFSAMYTPLVSFEPLALGLSALLNGNSSVLANFLTPESIKLVCDLENNELPQYNWDSDVLSGVLCTDIVDDVANRNISFYENLLNELKNQSETTGTAVTGAVPISCAGRKIRPPYAFTGPFTSPAANANDTKAPAAPLLITSSRYDPITPLRNALHVQKGHPGSAVVIQETSGHGATSNPSVCLVKIVRDYFYEGKLPESGTVCESVCKPTIPADKENCTSILSSRDVDYMLPPLGEFHWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGW5</accession>
    <name>A0AAD8XGW5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_614732</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366847.1">
        <property type="nucleotide sequence ID" value="XM_060507860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGW5"/>
    <dbReference type="GeneID" id="85391759"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40470:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G15850)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="33054" checksum="35E4DFD7E30BAFD2" modified="2024-05-29" version="1">MTDSSFLDHLNRDGFVVIPSILTESQLKELRSATHNATELARAGKWPNVRTLPKQFPPWPVATPESPPDGIWGVQGMMHPDMPNNAAFIKTYFSDAVIEPTKQLLQCTDDDLVMELFNLLIRPDEDFELRWHRDDIPATATAEEELDRLNKPAYSAQWNLALYDDNSLIVVPGSHTRARTDIERNADPYEKEIPEQLYVELKAGDIVFYNNNILHRGAYVANKERMTLHGSAGHVNGSTLRARNVLQHGLKGWVDKVDLGVLGEKERARAENMRRMLVKLGQEAGEVGYSLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGZ6</accession>
    <name>A0AAD8XGZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">S1/P1 nuclease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_650961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365996.1">
        <property type="nucleotide sequence ID" value="XM_060510415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGZ6"/>
    <dbReference type="GeneID" id="85394314"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957185" evidence="8">
        <location>
            <begin position="22"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="31150" checksum="470DBE439F316207" modified="2024-05-29" version="1">MARLTPLTLLAAAALPKAALAWGSMGHATIAYIATNFVAPETKTYFQQLLADTTDDYLANVASWADSYRYTTEGAFTSTFHYIDALDDPPHSCGIDLDRDCGPTGCIVSAHANYTNRLLQQPALSLEQRQIAAKMVIHFTGDIGQPLHCENLELGGNGIAVEFNGSSTNLHAAWDTNIPQSITGTGSSVLAVAKSWASKLSTEISSGDFKTASKCWIGGLSLEDPESQALAWATESNKFVCSVVLPDGREAVEGKDISGAYTTNAQPTVSMQVAKQGYRLAKWLDAIVAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG8</accession>
    <name>A0AAD8XHG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_615959</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366521.1">
        <property type="nucleotide sequence ID" value="XM_060507936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG8"/>
    <dbReference type="GeneID" id="85391835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="16291" checksum="31C3837B7BD7B21A" modified="2024-05-29" version="1">MCRSSFISHPRFRFLIAHKIQQFTTSYISRNSNLNIQQSPIYSGLVNMHLSAFFQLIAAALITPGMAFPADVKETGQAATSHTLPTAMTDSISAEEFNGAMTTVTTSAMCIHASLRALCPALCGITAIAGDEIFRECVRGCDCRSKKHGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI54</accession>
    <name>A0AAD8XI54_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HAUS augmin-like complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_651239</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365663.1">
        <property type="nucleotide sequence ID" value="XM_060510439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI54"/>
    <dbReference type="GeneID" id="85394338"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33774" checksum="063F18CEA8650006" modified="2024-05-29" version="1">MAHLPPSTAIFSPSIARIAASTAKDWSYVDSWLASKYQGRSVPSFERSPETLKALLALANTNEAADEERELVARAEAAALQELSIAQDRPETQSDLPTSATVRERILGTVQDHLTREGRTALNSLATLSCQLSVAHPDAESIGRSMIALHAEASELEQMRVRVHILQSHIEREAAMAREMLRTLKSDDYKPVADLARQNLDMQRRIKAMAARIPELKDRVATLKQSPAVSHPTIEKVAQDEADFLNLLAQKKGLDAEVGQFSALPDDVATARAELEHLRAEVRAVAQHRDAIFEGLVERESPRKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIV2</accession>
    <name>A0AAD8XIV2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368426.1">
        <property type="nucleotide sequence ID" value="XM_060510199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIV2"/>
    <dbReference type="GeneID" id="85394098"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="13436" checksum="7EFC695B5C043964" modified="2024-05-29" version="1">MTGHFGPDPGAMLTHRFLLLGRGRSLRALRMLCPMLASSRWLSLAQVYCDKVRLLCRVDNAQYCDPDSELHASLLSSMPSRPTMVVAVPRHFIILKRERRKPEMNCSDGPETRQQQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK39</accession>
    <name>A0AAD8XK39_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368892.1">
        <property type="nucleotide sequence ID" value="XM_060510184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK39"/>
    <dbReference type="GeneID" id="85394083"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="419" mass="45793" checksum="F6FA274A23DD876F" modified="2024-05-29" version="1">MASRVTDENEGPGDVRRIHSPATDPMAQDPFDDSDSDSDSELGELPSDEEEEDLFGFGSPSDELDGLPKDTEENRFGHPESADDEGELTQSPEDTEEDLSDYPEDDAEVQPIREYQEPLPARLAREHDRYRASKKIVQGPDDKPIMKSVQGFDGAYDMEPSGSSQDPAATPTKPAHHAVETPRTVKAPRISDEARDGKGTGAKKPGFGVAKAIDFNPSPKYYLGLSKTMKSDASPEADSAMAIDKHDVNRGPLTPPPGFRYDEESHGHPPPSRPRSAKTAPTVMFADTDVEDNSPSTRRHKNRVRIASVSKSASLERPSVQPAGPRPLGLEPDHYEPINAGVPATQTKAHRKRSRDHFEKTLTLAGKDTANMKEIMNNFALATNEKADNEVNEHGEDGEGDELTPKASILNSHMDVDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKA9</accession>
    <name>A0AAD8XKA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_691982</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368992.1">
        <property type="nucleotide sequence ID" value="XM_060511321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKA9"/>
    <dbReference type="GeneID" id="85395220"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="552"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="920"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="969"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="304"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="644"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="991" mass="108413" checksum="A47EF446FDCBC470" modified="2024-05-29" version="1">MANSTSDGCSLTADDAFGPTVQHCRDGFDFTLTFEQCLFTILPASLLILIAPLRFRYLGRLPYSVNGTTLRLTKQAAIALLAILQLVLIGLWSTHRGSSGSRLRTVSIAASCASFAATVMFAGLSYIEHAKSLKPSSILNIYILVSLVLDGAILRTMWLSHLSVAISAVFAASFACKAAIVILEAREKTRYLVPSSAGGRSYSPEETSGIYSRGLFWWLTPLLLTGFRRLLKPLDLFVLDASMSAAALNERFWLHWNKSTPSSFSTGDDDQPSEASRSPSRYRLIRTCIVTLKWQLLAVVLPRLFLLGFTICQPLILNRFLDFLQHPSESTNYGYGLVGAYGLVYLGISISSSFYWHAAFRCLTMLRGVLVAAIYTKTTELRVAPGDDSAAVTLMSTDVEAIVRAWREVHEFWANTIQIALATWILSTHLGYAASGPIIVSVFALGATVFLAPSAQKYQIIWVEKVQKRIGITSAMIGHIKSIKMSGLTQKLSQTLADLRLAEMRAATPFRVIGAVTSAVAQVPLMIAPVVAFAMYTTIASKNGDVLDATKLFAALSLIILLAQPLFWMFEVVLDMSAALGCFNRIEKYLSEPPRAEYRDLPPNSPASSCVLTGSFSQDVQLQNLESRGGQVSTDAKASGTIAIRVKEVTLAWKPETVPAVELMDFDILKGQLVMLVGPVASGKSTLLKGLLGELPHVTGTIALSSDRISWCEQSPWLINDTIRKNIICFSDFDQKLYHQVLQACDLEKDLAQLPDGDETLIGSKGIALSGGQKQRVALARAIYSRPQIALFDDIFSGLDNHTARAVFQRVFGAKNAILRAWGTTVVLATQSVSFLSQSDMIIALQNGKVVEKGGFDDCRKAGGYVSSLISANTEDQDESTPESEKLVDRTGSDALVEKNAKALKEQYDKRRQLGDWSVYGYYFGSVGASLVAVLMVLEVTWAFFSTFPTVWLKFWTDSQAESPVSHDAYYLGVYAAFQVSGVLCFAVLIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKG4</accession>
    <name>A0AAD8XKG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PHD-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_569588</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369054.1">
        <property type="nucleotide sequence ID" value="XM_060504211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKG4"/>
    <dbReference type="GeneID" id="85388110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="243"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="484"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="722"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="746"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="777"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="826"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="940" mass="103157" checksum="C4FB15D3BCF418EE" modified="2024-05-29" version="1">MTEKPQPLSTQTATPSQTLFAPSVPVSTHNVPRKAETVEEEEPYTIKCICNFTDDDGNTIYCETCDTWQHIDCFYPHSREEALREDFAHSCADCKPRPLDRQKAIERTRRLKNGPTTETIPDKKAKRPPSKSHKKKPKPTDLQLNGHPVGQENAKHGSPSDHPHPTKKVKSSHRPSHSISSQNAKRSPSYGNGGRSQPNGHPPSPATTPPDLPSDFQIHNYSDGFLSMSKEADIPITRINSFASLFVSNTLSVWLREPDRMRQETGEEFNDVFAKLPKDIDARKRQLHVESKKIPVSPETTLRWQYLATPAAIEKDVPLIELNGVIGFQKDYCADPENLWEELSSPLPFVFFHPMLPLYIDTRKEGSMARFVRRSCKPNALLDTYLSGQSEYHFWLMSDRYIAANEQITLPWDFRLPKKFQARLVHLLGLADDDTNTQNESEMDEAEYQTLSGWIHRILSEYGGCACDLGANCAFARFHRQHQAKVQSRPLAKKKQRKPKTHTISPTSTGHATNSRAASEGHQDDADNDGRSVSERSKPPSRDRTPVRQGSLDRPGILTEPTDRDKRKVQMVEDSFRRMEQQQPPRKKKRTSDGTASTSGSSKTKQRSSTSNASSGTTHYVDAGTSRSKSNSPSSGVSPTAQNPFKAPASRAESVGSQSGRTSSTPRPVYCDAGVQTDPVEGEWYSEPVQTPRPRRRIISLSQRLLNNRHRLRCDEVERRKSLSSLTAQEPTPMDVDQPAEIKPSAESSPPSKTIGNQARDTSPAAPPAGDVVMSDAATSSPSTVKSPLQADSVSDAPANGSSSPLKMRSPELRVTMPPVPAFNGPTSATPSATTPSTIQSPFSASSLPSPFAPTAVNGVAAHPSPVKKKLSLSDYTKSRMNKAKPAGALKTSLSGTEETKPTLDAIVDSPVVEKSADVLTPVTGNTINSNPAATAANTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL78</accession>
    <name>A0AAD8XL78_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_568371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369495.1">
        <property type="nucleotide sequence ID" value="XM_060504062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL78"/>
    <dbReference type="GeneID" id="85387961"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="186"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="523" mass="58588" checksum="130E0625C68431A4" modified="2024-05-29" version="1">MKAASADPFGQILKDLVLIVISIAFIPLTTIILALSYAWQRFLRPGQAFDPAAATDRQQQQRRTILVTGVGMTKGLTLARLFHQAGHRVVGADFSPHACGSRSAALAAYHILQKPGRAGGGADPYLDSVLRIVEREKVDLWVSCSGVGSAVEDGVVKEVVEARTRCRAVQPDVARTRILHEKDSFMDHTRETGLRVPESYLVTSRHEMLAALDEASGGLSYDAESETTAKNNRKPPPRFIAKSVGVNDRGRGDMTLLPLPTEKQTYDHVYHLEWLGLSDKEPWLLQEFIDGEEFCTHALVVRGEVRAFVACRSAELLMHYVALPASSPLSRAMLEFTRKQAASFGDAYTGHLSFDFMVSYEDVAAAEAGDGCKPEQLKLYPIECNPRAHTAVALFGETPDMVERYLSVLDEMGTSGGSSETDVVTPRRPAKYYWIGHDLFTLLLLPTVRVLLLRVSIAAYWRSIKTFVEHVLFWKDGTFELWDPLPAWWLYHVYWPMTFWDCVVNRRSWSRINVSTTKMFECD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM10</accession>
    <name>A0AAD8XM10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_748162</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369838.1">
        <property type="nucleotide sequence ID" value="XM_060513573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM10"/>
    <dbReference type="GeneID" id="85397471"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="160" mass="18635" checksum="470E24C359FF39BB" modified="2024-05-29" version="1">MSDVRGHLWRSHRVPYHCPICIQTFVSATGRDEHILKRECSLKEYPTFLGVTQDQEDLIQRTQDISGGKYQWFAIWRIMFPKQHRKPKSGLLNDTIGAEICNFRAWYKTRGLAWIRNSVEELKDSTGYIEEVEKCATELRSMVLSEAINTFVDDILRTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMQ7</accession>
    <name>A0AAD8XMQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Complex I intermediate-associated protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_603218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370194.1">
        <property type="nucleotide sequence ID" value="XM_060507215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMQ7"/>
    <dbReference type="GeneID" id="85391114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF18">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="6">
        <location>
            <begin position="44"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="31052" checksum="63E46900B5CF4C78" modified="2024-05-29" version="1">MRATPSLMAKGIFSRTMDEFKRRASIVAKAEGIKGPSGPYILQDFRAPGSTDDCKLLSDQEIGGFSHSALDWVSSSPSSTVTTTSPQSTPTTSAGHARFHGTISTDLPKNDPKIQRTGFAAWRTPDQKPTLFGKAVWDIDPYSYLAMRVKSDGRSYFINLQTDSVVPTDLHQHRLFAKRPGEWETVFVKWNEFVRTNHGFVIEPQTEMLRSKVTTVGVGLTDRVPGPFELCIERIWATNDVDEVDGGSGSDILAAQEAREARESELRNRQGESVRWKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMT3</accession>
    <name>A0AAD8XMT3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE affecting a late Golgi compartment protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_401603</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370380.1">
        <property type="nucleotide sequence ID" value="XM_060502848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMT3"/>
    <dbReference type="GeneID" id="85386747"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21444">
        <property type="entry name" value="SNARE_NTD_Tlg1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15851">
        <property type="entry name" value="SNARE_Syntaxin6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.90:FF:000012">
        <property type="entry name" value="SNARE domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000006">
        <property type="entry name" value="Syntaxin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015260">
        <property type="entry name" value="Syntaxin-6/10/61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048036">
        <property type="entry name" value="Tlg1p-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09177">
        <property type="entry name" value="STX6_10_61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="176"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1730325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="29125" checksum="E2221E6E0173BF0A" modified="2024-05-29" version="1">MMSSANEEDPFLQVQQTHYRDVLAQLDSTRPLFTSYLRIRSLSTSPTSPELASARADLESALASLAEDLADLVESVKAVESDPTAFGLSGPEITRRKRLVQDVGGEVEDMREELAKKLGAAAAAAGGGGGGKGKSSAANSDLPDPSSFAIGDGHHGDHDDNDNDDYAAEFEQQQQLEMMREQDGHLDGVFRTVGNLRRQADDMGRELEEQREMLEVVDGVADRVGGRLQTGVAKLQYVMRHNEDRLSSCCIAVLIFVLILLLILLLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMW6</accession>
    <name>A0AAD8XMW6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP dependent DNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_566994</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370440.1">
        <property type="nucleotide sequence ID" value="XM_060503910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMW6"/>
    <dbReference type="GeneID" id="85387809"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08039">
        <property type="entry name" value="Adenylation_DNA_ligase_Fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF2">
        <property type="entry name" value="ATP DEPENDENT DNA LIGASE DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G02430)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="7">
        <location>
            <begin position="378"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="688"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="773"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="860"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="944"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="860"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="948"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="964" mass="108694" checksum="A482572BA30667EA" modified="2024-05-29" version="1">MPVSFVLVCDLLEQAYKQCKAGDKNLKQRVSNWFTLNRHRIDDPETDASALLSTLLPDKRTDRVYCIQADTLANIIGRTFGLGTSRLQELRRYKEAGRGEDLADCVERVFKETPPPICVGKDAVTVEEIDSTLNNLAALCRFSSPVVRASQPHPSNINRQELLGHVYLRLQAREAKWLTRLILKNFQPVMLDPSHLYHCYDPLLPMILRVQDNFDAALSLLRKLRKEPSFLHGSGNQKRRDLMQHLTPVLGTKVGRPFWLTGRSIKHCMKLIQGRMSCEKKMDGEYCQIHIDLSKGFKCIQIFSKSGKDSTKDRAALHGAIRDSLNIGKSNCKLSKGCILEGELVVYSDLEKKIMPFHKIRKYVTRSGSYLNTEADSQRYDYEHLMIVYFDVLLIDGESLLGTGQNERFERLTELINRREGHADLVERQVVDLNDRLGVHYLRRAFAESITAREEGLVLKPDDPYFDFSESRRSFAGCPIKLKKEYIGGFGDVGDFAVVAARYDADKAKCYGIPNLKWTHFYLGCLENKEDVERCQAQPVFTVVHQVELNETLLKTVSTYGNPMPVSFDDNDALILHLAPGIAQQKMPAVVFTEPLVFEVRCFSFDKEGNTNFWQPRFPQVSKVHFDRSFIDTISFSELQAVAEEATTTPAMEDSQEMLDWIAKLERADPRGIPVDVVSQAAEMDFTAEDNTASEAANSPRASKRGLEGEDATPQKRPRVSSESGTAGRELPPPTRRPLGDISANQTSLSPQASQTRPATTKRIVMDQKAASPNVPVLHEPGKPMAGSAAETPEPRHQSAAYPSSTQVKPMCQHAGDNCLFTDTIVLLAPCIAQQPWVTENLLPLHGIHEWTADPQDWTASSDRIASSSSHSTTPASTSATNRPRRKRPRKICFVEHNRREGTKILMRRLDSNPVYTLNGRREYVEVYDWRLLEDVTALEKVLKGSKPSKEQPDPKRKWWVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNT4</accession>
    <name>A0AAD8XNT4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_341850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family. PalF/RIM8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370883.1">
        <property type="nucleotide sequence ID" value="XM_060502460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNT4"/>
    <dbReference type="GeneID" id="85386359"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF161">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALF_RIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="306"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="612"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="775" mass="84164" checksum="587DDADB17141F4E" modified="2024-05-29" version="1">MGAYSHSNGSVEETTSSARSFFSRFALPSRSRSRNLADFHVRPDDPHRQYSAGDHVYGAVVLTVVKPIRITHLTVALHGYVRVHKGPAVSEPPVAKPALSGRSSAQYHGNGYASLFQDEQVLSGEGRLEAGKYEFKFDLVFPEKGLPSSIDFERGTISYMITATLTRPTSISPTSSCDRKIQLVEQIDIGSLAPPRPRTIYLEPISKKSRRKRTAGNEKNPATVETTEQGSDVEPHDAERTVESPAPTEDHPHDPLEYPRSPTHTDIQSEVSGDSTVSSSTGISLARAEPQLASSSLTNSKMQAVDEKTITATIEMLKGGALPGDTVSVKVSVQHIKRIKSMHGVIVTMYRQGRVDTAPPASMFADIMSKEETRKLAKEDYYPRSRTGLGGLSLTSTSSLSVFRKDLSQSVAPLIIDPVTLETTVTASLKVPEDVFPTIKGVPGDMVSFKYQVEVLVDLGGRLASQLQGGGQSRVAQFAPGSGATDGNNAALNSWGGNVIDTDRLRREKGVISVVFEVILGSTDSSRLRGRSNTLRTYQMREGSLSREEVSSPWPIDDNHADDGESYWPQPPEMPAPLSRQPTITIHPTSPPEEMQAPAYVPPPQVPDEGSMTEKERARRQEERLLPSRPPQMSEAGPSGASAPEPNIYDAEDEPEPEPQSHHRGANGVEEEPSAPTLNDISTHQEARTEDKQELERQRLMVEASAPPEFPDDYDAGPSASASAPPADVAEPSAPVLADEDDYGQQYSYSTEAGTGQSSHQHHAAGSEPLPRYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPT2</accession>
    <name>A0AAD8XPT2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_159895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371502.1">
        <property type="nucleotide sequence ID" value="XM_060501389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPT2"/>
    <dbReference type="GeneID" id="85385288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="10">
        <location>
            <begin position="505"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="618"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="280"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="439"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="781" mass="88011" checksum="4023DAC8E818D365" modified="2024-05-29" version="1">MCLSFWRRKTVPSDEKTQKKRTLTMPLWSSSNKTSANTLKKMVGLTTLLAPTRDGFHFQPAPRPMPLINITNVDGATDPSSSSSAASDPKEAVVAPSPDEILLSQTIRDRFEKIFNDLRSRRSSLSREPFVTRDQLLVFLENTQGEIDVEAVLPESQQRYNYGEFLELWWRNYGWDATRPIKEEDKDLSRPITNYFISSSHNTYLEGNQLASRSSPEAYKTVLRRGCRCIEIDIWNGDTPITTQEGSRSPKPDHSRNLSGSSLPNVAASVKETVEDLLIERSTNGNGHHRNTSTASKSLNPRDSATLLGPSESTDSLGKTLRPSSPTPSMKNRLPYPKDEPIVTHGWTLTTPCGFREVCKAVRESAFETNELPLIVSLEVHADKDQQEVMVKIMKEEWEGMLIDKSWEGIDPRFRLPKLEELKRKILVKVKKAPNKIEVPPSTTALSQKFANDEDASGSDDEHTKEAPKQETPKPPMTPKFDAPAKVHSGNEPAKSTKVAICQALSSLAIYTHSEHFKSFETPAAKKPSHIFSISENRILELHTTKAREMFTHNKNFFMRAFPNGSRVDSSNPDPSLFWRKGVQMVALNWQYLDEGMMLNEGMFADELGWVLKPIGYRSTDKDTLTEVDAAPQGDLELTVTIIAGQHIFVDDDSASDSSRGKHLRPFVKCELHVEIGAQNGKAADEDDFKLKTGSRKTDHPEWENGARLKFPKISRVVEELSFLRFKIEDDPLLGGDELLSWACIRLDRLRPGFRFIRLMDTKNRPIEGGKLLVKIDKVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ59</accession>
    <name>A0AAD8XQ59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal recognition particle receptor subunit alpha homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Docking protein alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_160303</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371516.1">
        <property type="nucleotide sequence ID" value="XM_060501392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ59"/>
    <dbReference type="GeneID" id="85385291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005785">
        <property type="term" value="C:signal recognition particle receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14826">
        <property type="entry name" value="SR_alpha_SRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000566">
        <property type="entry name" value="Signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.140:FF:000009">
        <property type="entry name" value="Signal sequence receptor alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000023">
        <property type="entry name" value="Signal sequence receptor alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007222">
        <property type="entry name" value="Sig_recog_particle_rcpt_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04086">
        <property type="entry name" value="SRP-alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="12">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="152"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="271"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="683" mass="73434" checksum="269B43EC048A94D7" modified="2024-05-29" version="1">MLDTFEILTTSGVVLWSRTYAPVNPSVINNFIADVFIEEKGGAASSQSAASNPPYKRDQHTLRYTFVKELGVIFVAVYRSLLHLSWIDKLVDNIKTIFVDLYGEQLTKPHTTVVECHKFDEYFDQQVRELETTGAKGDSNVSEADFAKEEKTLSGNLGDDPPLPPGLHYRGRGLNSANETSNDSTPIATPTTSRPSTPGTGGVLVGKAGPVAKMSRRARKAGNSAPLSSGDESAGRRPKPATRSSTKKGRKWDADGMADEEDDVVLDYSAAPKSATSDSEAETTARSSAVEHVDHTTWGSKTSKGQFVLKDLDDEVHNILASAQAKNDSSNKTEASGGLIGSGLSTIGGLFRNVVGGKTLSKADLDKAMKGMEEHLLKKNVAREAAVRLCEGVEKELLGAKTASFESINAKIQAAMEASLTKMLTPTSSLDLLREIDAITAPPATSLRKARPYVISIVGVNGVGKSTNLSKICFFLLQNKYKVLIAAGDTFRSGAVEQLAVHVRNLKELTVREGGRVELYQKGYGKDAATVARDAVAHAAQDGFDVVLIDTAGRRHNDQRLMSSLEKFAKFAQPDKILMVGEVRLPPPSHIHNQTTTDLSPKALVGTDSVAQARNFNAAFGSVRTLDGFIISKCDTVGNMVGTLVSLVHATNVPVLFVGVGQHYSDLRNFSVKWAVEKLLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQH2</accession>
    <name>A0AAD8XQH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein YAE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein yae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_646069</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">May form a complex with LTO1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the YAE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371623.1">
        <property type="nucleotide sequence ID" value="XM_060509913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQH2"/>
    <dbReference type="GeneID" id="85393812"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="11">
        <location>
            <begin position="84"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="26600" checksum="1DAE80859F3B1085" modified="2024-05-29" version="1">MHLQPIDNTEIEPFTSAMDDPHITILPEGQQSQETFDDVWGSEPGSPNHHAGHNNFAQDAASAAPMGTHPGDMPRLQAEHTNAGYREGISAAKAHSIQAGFDEGFSLGAEVGSLAGQIVGLFEGIAAALDGHGHDEDASKKARQTLDEAKAELKIDSIFGPAYWNTDGTWKFDVEGGTNGGDDEILFADVARAHPLIRKWQKVADAEIEQWGILLEAIGDAQDHERQPSPERAPSSAVPQTKKPLDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0I4</accession>
    <name>A0AAD9D0I4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568764</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369410.1">
        <property type="nucleotide sequence ID" value="XM_060504117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0I4"/>
    <dbReference type="GeneID" id="85388016"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="108"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="35301" checksum="BD4DF98FED4C018D" modified="2024-05-29" version="1">MSSSNSASPSSNSYLEQTASMLSTVGAYMRLPAIASTGIAAVLTSLLYFKQKALIYPSHMPANSRTDVPRPSQYGIKDFEELVIPTNDGEKLSAFYIRGPRGGKNSNVTILMFHGNAGNIGHRLPIARMLINFIGCNVFMLEYRGYGLSTGEPDESGLFLDAQTALDYLRSRAETSNHKLIVYGQSLGGAVSIKLVSKNQKDGDIAGLILENTFLSMRKLIPSVLPPAKYLTLLCHQVWPSESIISSITTVPILFLSGLQDEIVPPRHMRQLYELSAAPSKIWKPLPAGDHNSSVLEEGYFEAISDFLGNVTGVTSKEEKQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D183</accession>
    <name>A0AAD9D183_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_400455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370337.1">
        <property type="nucleotide sequence ID" value="XM_060502838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D183"/>
    <dbReference type="GeneID" id="85386737"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="16402" checksum="5939E5AED4DF3E99" modified="2024-05-29" version="1">MTRGIPTNRKAPHSSPTLTRKTDSATPGVKRTICSTTLPSSVVSPACKWHSEALKWAPPQGLIENLPKSLRPSAGRPEQEGEPSTRKTSDDSRSWTGWARLPARISVPGPPTPTSDPWLPLESRACLGASAFSRYVDETLSYIQFGIYSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1Z4</accession>
    <name>A0AAD9D1Z4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_602316</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370370.1">
        <property type="nucleotide sequence ID" value="XM_060507163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1Z4"/>
    <dbReference type="GeneID" id="85391062"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="7">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="202"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="318" mass="37499" checksum="D4EC320032AE2F54" modified="2024-05-29" version="1">MASDEIIWQIINQQFCSFKLSTEKKQTFCRNENNVTGLCNRQSCPLANSRYATVRRAPNKDTLYLYMKTIERAHMPSKLWERIKLPNNYAKALEMLDDKLIYWPKFLIHKCKQRLTRLTQVNIRMRKIAAEEERMGEKLVPKMAPKIRRREEARERKAEAAAKLERTIERELVERLRSGAYGDQPLNVSESIWRKVLNSMEKEGAGKRDKDMDPGMESEQEGEEEDESEDDLEKEVEYVSDIEESDEELEDIEDWLQSDDDAEDDNEEEEDDDSEDSDEEAARKAGDKRKRGRAVKMNQKRLKQKQEERPKIAEELTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2N1</accession>
    <name>A0AAD9D2N1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_715426</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370791.1">
        <property type="nucleotide sequence ID" value="XM_060511745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2N1"/>
    <dbReference type="GeneID" id="85395643"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="55488" checksum="9B47D3BAFE36ED9E" modified="2024-05-29" version="1">MQLSVLWRAPEVNPINRKARSIPVFNIFNVYARAFHFSWLGFMIAFWAWYTFPPLLTVTIKKDLNLTTAQVANSNIVSLVATLFMRLIAGPACDRFGSRIVFGSLLLIGTIPIGLAPLVKDATGLYISRFFIGVLGATFVPCQVWCTGFFDKNVVGTANALAGGWGNAGGGITYFVMPAVYDSFVHARGYSPGQAWRLTFIVPVICLFCCGMGLLLLCEDTPTGKWADRHLHAQENLHSHGVDATVRSDVVDVPGGITDRNNNSMASDEEKNSTHGKNGVVSDHEASLSRTEMIETAQADTVVNPSFKEAMQVVFSAQTIFHVATYGCSFGGELAINAILSSYYLKNFPSLGQTGASNWAAMFGFLNVITRPAGGVVSDLLYRYGGQNLWLKKGWITTCGVLTGALLILIGQLNPHNESTMFGLVFLMAVFHEAGNGANFGLIPHVHSYANGIVSGVTGAGGNFGGVIFAIIFRFMDQGTNYAKGFWVIGCIHIAVNLLVSWIHPLPKAQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3F6</accession>
    <name>A0AAD9D3F6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_646141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371705.1">
        <property type="nucleotide sequence ID" value="XM_060509925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3F6"/>
    <dbReference type="GeneID" id="85393824"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="34803" checksum="35F7D1BF55FF8381" modified="2024-05-29" version="1">MPYQAIGYSENYCEMHTGLWGAGLRLSRIHKGVYFWRLLIGNNTTLSTNSGGRMCLDRPGIVCADIGVQSVPLGVLAVLLCRQHGSVNALPSSLNIDYLKESVWLIDFDTLILSNIRLLELSNVQPKMPINLDNISFYSAPAQAVRPLAARSTTRQTPSPSCSVMGRTAIPPSDDTTTTPDQIKSHRDKKPIVSSQSLPESNVEGKVNSNDKPYLRIERCPGSGDMGHSSAKKPVTVDFNTRENSPETAAWSANCLPVSALSLPSEAFTAAMLPSYPDPGPQAANNTADQALPQKSTKNASTVSSETLLQRALRLTPSILPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7U0</accession>
    <name>A0AAD8U7U0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_757354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359037.1">
        <property type="nucleotide sequence ID" value="XM_060514886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7U0"/>
    <dbReference type="GeneID" id="85398784"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF2">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="2">
        <location>
            <begin position="58"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="38544" checksum="A20A86BFE16B0C7C" modified="2024-05-29" version="1">MPSSKPLKIKPSEVAADTKKKLIPEVNRYFREEWPPYSVLYSQPLLQLPLSRPAFMSSDLPNFYVVHSDPVDCALGWAQSEGVRIPFICAANEKRPGGDWETGVVGYEERLCRRSNLSATLGSPHPDTCMPTNYPIPIEGAIYSPDVVRFRQFQDRIESLDMKDWRSLPVISMPPARWPKLTDMGRKYSFSEERELVRNKMRAALRICVFNGYNHVVIGDFGLGNGYRNPPKELAELWREVFLYDPELRGQFLAVMFAFEDDRQCTAKFILDDIAKKTKGSSSSSSSKSKSKSSSSSSSSGSSSSHKSDFKIFSEIFATSEIARVRSQPDPRYAFSAIMDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9I4</accession>
    <name>A0AAD8U9I4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_643851</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000232">
        <property type="protein sequence ID" value="KAK1706101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357749.1">
        <property type="nucleotide sequence ID" value="XM_060509700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9I4"/>
    <dbReference type="GeneID" id="85393599"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000095">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="54"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1706101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="49498" checksum="C72E703E78B64778" modified="2024-05-29" version="1">MQFARSTTLITSAIVLLTTIFLTHTYTNLFTRLPIPFFQSNTTVTMGGGPVQGFRSVAYFVNWAIYARKHRPQDLPVENLTHILYAFANVRSDTGEVHLTDGWADTDIHWEGDSWNDVGTNLYGCMKQLNLLKRRNRNLKILLSVGGWTYSSNFKAPASTPQGRDTFARSCVDLIKNLGFDGIDIDWEYPQTPSEASDFVALLQAVRSAMDNYASTLPEWYHFELTVACPAGAQNYQKLNLPAMDPLLDFWNLMAYDYAGSWDTTAGHQANLQPCRQNPRSTPFSTAAALAHYTSHGVSPDKIVLGMPLYGRAFENTDGPGTPYSGVGEGSWENGVFDYKVLPMPGAQEYHDEETGASYSYDAGKRKMVTYDTVHMARKKAEYVRGWGLGGAMWWESSADKPGHESLIGNVVHTFGGPHGLLRRDNCLTYPETKYDNLRNGFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9K9</accession>
    <name>A0AAD8U9K9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_796228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360042.1">
        <property type="nucleotide sequence ID" value="XM_060515861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9K9"/>
    <dbReference type="GeneID" id="85399759"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1714580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="574" mass="63688" checksum="262F4434C54A936B" modified="2024-05-29" version="1">MEGPFDAVVVGAGWFGLAAAKAYSQLHPTANLAVLEAAESCGGTWSQNRLYPGLKSNNMIGTYEYPDFPMSESVYGVKPNNHVPGAVLHRYLTDFAKHFGFFDRIQFNTAVNLVERNGEKGWRLSVASPSGERVIQTEKLILATGLTSTPNLPTYSGAETFSGPLFHAKDFCKRASELKGVKNAVVVGGAKSAFDVAYALVQDGAEVDLIVRPNGHGPVWIAPPFVTPFKKRMDQLLNIRWMSWFSPCPWGGEDGYSGVRQFLHGTTFGRFIVDSFWKVLSGDVLSANAYDSHPELQKLKPWHSAFWIGSGLSILNYDSSLFDLVKEGKIRVHIDNIDRLEGNKVYLSSGEQLETEAIVCSTGWKKESTIKFAGLNEEKLGLRYSATEKRALDQEADAKVLELFPRLGDQPKLRFTPKEANPLRYYRFMVPSTMVGSRDLAFAGMISTVSTSVCATIQGHWIAAFLGGQLDRLPTSDQEITDEIMLHTQWGKWRYPCGYGADLPDFVFEGLPYVNMLMKDLGVETHRKSSRLQELTSPYLPADFRGLVDEWKQGHGACEIEIATHKVITSGTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAA1</accession>
    <name>A0AAD8UAA1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_55783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360346.1">
        <property type="nucleotide sequence ID" value="XM_060503532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAA1"/>
    <dbReference type="GeneID" id="85387431"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053169">
        <property type="entry name" value="MUG_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791:SF2">
        <property type="entry name" value="ENDO MANNANASE, GH76 FAMILY (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47791">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 191 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042094197" evidence="2">
        <location>
            <begin position="28"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="647" mass="71268" checksum="634B16AD763EE014" modified="2024-05-29" version="1">MPRSIPRLPEACLSVLALSSCATALIATPPNAPETYCPIFYAETQPPTDCEPRQPASFLETPQVGREATAYTAKAKDEPLEATFEALTVMQHDFFVSDQGTWPEAIDWTAAVMETMLSGSLTSLSQALAVLDIGGSGDKGAKRNLIDTFFTQLVASYFGQDDVAIRHQAFDDILWVVLGWIDAIKFIDIHSKLFYPREGLNESATPGLGDALANGPWHGQYWIPSFAHRARIFWDLGSKGWDTRLCDGGMNWNPRLEPYKNAITNELWIAASISMYLWFPGDNNTTPWINRASGVEATREPKYLAAAIEGYRWLTGVNMTNHAGLYVDGYHVDRSKPGNTKCDQRSEAVFTYNQGVLLTGQRGLFAATGSASYLEDGHRLIQNVIKASGWDLRLNKPLDDLSKLPPGYLPPWRGLGRGGVMEETCDASATCSQDGQTFKGIFFHHFVTFCQPLDAAIVERGMTVNARAYDQVKTTHASACQAYLKWVEHNAKAALLTKDREGRFGTWWGAGIFLKSAPTMQTDGIPHDAPNVTDYRNYGLPHDGVWAHDNPDEVWAPNGEARKNEKKGYVLVGDDEHSGQQVLGGSDRQGSHKADEVGSERHVKSTAATGDPNDRGRGRTPETQNGGMALMRAWWELVAASNGTYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAN7</accession>
    <name>A0AAD8UAN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_772574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000276">
        <property type="protein sequence ID" value="KAK1703673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357336.1">
        <property type="nucleotide sequence ID" value="XM_060515389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAN7"/>
    <dbReference type="GeneID" id="85399287"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1703673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="34117" checksum="63A9BDE21B78980E" modified="2024-05-29" version="1">MAIEYEVKGKVALVTGAGSGIGLAITQRLLTEGCSVMIADLALRPEAETTIANFPHPSSSADKPSAAFHKTDTTNWAQLKSLWAATLERFGRVDIVVNNAGIFEPPWSSFWNPPGVSPESKDDADAEVGSYHIFNVNTIGPIRLAQIAIDYWLQNREVKGNLLWVSSMGGYIHSIQTPFYFASKAAVLSVVKSLQGLKKLVGIRNSVICPGPTRTPLFDQEFCRDRLPAEDLALSSEDLANAMFSLLTEEQYGNGNVLEIMMVGSKEEPKVHTKEVQLEALYPTASPMGAGTKAMEAELNFMGMIAEKGMRSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAP0</accession>
    <name>A0AAD8UAP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_93952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359507.1">
        <property type="nucleotide sequence ID" value="XM_060516020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAP0"/>
    <dbReference type="GeneID" id="85399918"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="635"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="741" mass="81647" checksum="DBD29C7D4FAC68C4" modified="2024-05-29" version="1">MSNYIKITDVELTDQPSGGAPKQAQKSARHGAVPRSLASGEQQFTHEVRTKRWWSRMGKKGWLILALGMVVILISCTALALLWNGAVIAASGEEPSELWKAVVFNDWAPTVITICSAAIRTSMMMQAGLITAAISALMLESSRVSLADAAVASIERAASTGPFAIFFPAARQGNNLPGLYHLLFVIAASGIMVTSTFFSTILLSDFQTLSISGPATNITVSVAFRNDGTELRGSGVSLFKSSPATYWRYGERNDDGALSGPDIVDTGNVYRALLPSINATARTTLEYYNGPVIIANSRTFCSAPDFETLEVYNTNSDGLFGVKVDASIPIGKHLKGDTYKDAIFQMSFDCRLARIGGHYKDESHKPIYDSNLWPLTFCPGRYWDGDGFKGLSEPVKGTEYMFHVILVINSSQTIYEKYVDVDNLSPVYDKSGVWTSIQDNSSFPLFNASLCFTNVAEPAVYNATMRGQPILQEPQFNWNSIKWNTSSIRRQLGIASPAARSSAAVFTERGIMQLISFTLSSEEKLWWTVSAHGVLMESLSATLETRGWNMLNGAYLGETWSTRSPEHEQEQWTPHSAHVTLFQDILQTTEDLSRAVQEMVARLHQMAYYESENGYNLEYPVTTVSSRSTYIPLRWTGFSIVQGVIALHLVLLLTTTVLFLTRTRASSLGNAWKTVAQVVSPHTKEIGDKADRLMDDEVRERTVSTGADVFGVGIRRSADTSRVEIRPAAVRARRLLGRDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC06</accession>
    <name>A0AAD8UC06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_654908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361377.1">
        <property type="nucleotide sequence ID" value="XM_060510761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC06"/>
    <dbReference type="GeneID" id="85394660"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042284360" evidence="2">
        <location>
            <begin position="21"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="35313" checksum="5560D3F9E48D2396" modified="2024-05-29" version="1">MIAPAALLLAFLSLTPSAIAGGDKRRCSPLNKDYENYAQNIGMRYKEECIRVGLHVSNTGACRVSCDHLPTYYEWANIYELEKTARKKARLQEREREKQRMADLAKKLGLPPLYNTTTPDPSMASVLPVAAANDKVETKPTSPEEPAVLLSPRGITAAPAPTAAALKMANAPIRPCKREEISAQDSLCTLGRGIPRYAKIQAALSSSLQAAASTINAKASSYRVLLNDAKATAVDKTATVTATVEKLVTKCLSSSSSAKASTTKTADSNTTPAPTARSTSAKKQTKATRTTSSVKPTRTIYVASEGSSTSIMWSMLVAWIGIQVLFLTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCC5</accession>
    <name>A0AAD8UCC5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anp1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_722156</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361396.1">
        <property type="nucleotide sequence ID" value="XM_060512444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCC5"/>
    <dbReference type="GeneID" id="85396342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF4">
        <property type="entry name" value="N-GLYCOSYL-TRANSFERASE (AFU_ORTHOLOGUE AFUA_4G06870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1719312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="46200" checksum="60B8A38DF6847B67" modified="2024-05-29" version="1">MLLPKGGINWKSAQARLPPTRAVWSFLTRTRFLLLVALTGTILLLWRGIRSSASEMQSFYCWGPAKPPMEMSLNEQASWAGHLQTPVIFNHHEPLEINHTSIIHVDLNPIKSTRKAVTNEERVLILTPLKDAAPYLSKYFELIAELTYPHHLIDLAFLVGDSKDDTLAVLASELDRIQRRPDKIPFNSAMVVEKDFGFELSQSVEERHSFKAQGPRRKAMGKARNYLLSAAMKPEHSWVYWRDVDIVDSPKKILEDFIAHDTDILVPNIWFHRYRDGRDIEGRFDYNSWVESDKGRRLSASLDKDVVLAEGYKEYDTGRRYMAKEGDWRNNKDDELDLDGIGGVNILVKGDVHRSGINFPCYAFENQAETEGFAKMAKRAGYRVVGLPNYVVWHIDTEEKPGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD27</accession>
    <name>A0AAD8UD27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_630731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361947.1">
        <property type="nucleotide sequence ID" value="XM_060508848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD27"/>
    <dbReference type="GeneID" id="85392747"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="77" mass="8660" checksum="E27639515B6076F9" modified="2024-05-29" version="1">MCKYITHLRVCNVCSHQDTVLISERPCFLAKKNGVFGSCDAGIGSDRSCTRYHCWKCKEKVLLIPQPSPVSLHLSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDA1</accession>
    <name>A0AAD8UDA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_586900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360763.1">
        <property type="nucleotide sequence ID" value="XM_060505987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDA1"/>
    <dbReference type="GeneID" id="85389886"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="39721" checksum="4563699D631ECC84" modified="2024-05-29" version="1">MAPPFRVTWARITDRTMLYNSLERVQPWLDDWLRVVEAYSGKSLSKPEDRLPAIAGVAAHFQQNIRRPDQFLSSYVAGMWFCDLKRGLSWKPSFDLGTPRPAKDKGWPPPLRNSATFNAIPETQSEPLSVWLPSWSWISVDDRVRYPYARGSSARPTVIGMGGMEYLNPKSQNFDDISVPDTPLEPFFGRTSLKTDFEFGELEWGVIGLTNYAVETVVSEKHLIKDSIIVTGIPKCYSIFKQSTNPFKITRRSEPSAGGVIVMDTSPAQLPKTKLYCLRLGNSKSLFNNENLVEIGLVLLETPYKSMTGLSSRWHSRSGPVVQRVGFFEIGMWDKQWVRNARQRNFYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDC8</accession>
    <name>A0AAD8UDC8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_679367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360808.1">
        <property type="nucleotide sequence ID" value="XM_060511188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDC8"/>
    <dbReference type="GeneID" id="85395087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000064">
        <property type="entry name" value="Probable acid phosphatase Pho610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF15">
        <property type="entry name" value="ACID PHOSPHATASE PHOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042297494" evidence="2">
        <location>
            <begin position="17"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="47168" checksum="D2202DE90E4CEBFD" modified="2024-05-29" version="1">MRCAVAAAFLAAGAHAAAVTPLAARVTSSSSSGGWETRYTATGSAAVAAAAATAKTSSPTSNVKGKAFDRFVIIWNENTDYDKAIGDPNFAWLAKKGITLSNNFAVTHPSEPNYFASVSGDYLGMNNDNFNRADRNVSTVFDLLDTRGISWSTYQEDLPFSGFEGMAWVNQTTGANDYVRKHNPPIFFDSVTSSEQRLSQIKNLSVIYPERSSFHKDLKANKLPQWIWVEPSMVNTGHDSSVTVSGAWNRKFLEPLLEDKNFMNNTLVLVTWDENETYTQKNRILGILLGDAIPQELVGTTDSNFYNHYSELATVEANWDLPTLGRWDVGANVYKFVAEKTKSVLRQWSNTSTVPDRYFNQSYAGFFNSKTAKQYPKPNLALDENAAGRKILESVKATWKDSKAPTYYEDTVQVLDGLNPPPGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDP3</accession>
    <name>A0AAD8UDP3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Cutinase</fullName>
            <ecNumber evidence="3 13">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_709718</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 13"/>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359661.1">
        <property type="nucleotide sequence ID" value="XM_060511575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDP3"/>
    <dbReference type="GeneID" id="85395473"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000235">
        <property type="entry name" value="Cutinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF3">
        <property type="entry name" value="CUTINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042244332" description="Cutinase" evidence="14">
        <location>
            <begin position="16"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="44"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1713335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="226" mass="23450" checksum="9782226DDC5E5371" modified="2024-05-29" version="1">MKFLSTLVLASTAFAYPTIPQEEAKRQLGGTVGSTANEFKTGGCNDIIFVWARGSTEIGNMGTVVGPPVANNLKAAFPGKVAVQGVDYAAGLDTNFLPGGADPVGINQMKSILSDINSKCPTAIVVTGGYSQGAAVNHRAIENAPDAQKNQIAGVVTFGDTQFRADNGQIPNFPKDKIKIICAANPRDTVCDGNLSAAVLAPHLSYGANAKEGADFLIAQIKKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDS6</accession>
    <name>A0AAD8UDS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_755483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361157.1">
        <property type="nucleotide sequence ID" value="XM_060514619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398517"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.790">
        <property type="entry name" value="RNA-dependent RNA polymerase, slab domain, helical subdomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF14">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="491"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1342"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1352"/>
            <end position="1365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1365" mass="155147" checksum="3D64BC6362A9CCBD" modified="2024-05-29" version="1">MAPHTKSALSAPRTPKKPTQTDRVRDVIDKLNREYNLAIEIPDVTLTPSSTRQRAEQDTAFARSEKIVRDIRFHCFQSNLLDRILNSFHMEARAASETWIRLFNDAEPIPGPGGAPKAESPGQLLELQVILSDILDKAHAQVKARKLTRNHTGPAVFASTESSKSKRRSEIDTKAESPKRVRGSPLRGEEREGVISNALDKIPSRSRSAIPEAMPAQFTRETWRPNKSFDTSLYTSTSVRQSVCGTISHTTSASTSRTSLFSKVDDRLPCTQETVPVPLEEEEMRREFLDQAPNSSQSQELFPASSGHLDALNISFTEHEVESAKKRSRTPADLRPEPLASPSKRSTIYSEISGLQDPCLCEPVSTPLKRSEPVDLRSRLDASWPRFPRWLNRAPFAVAWEMTRIAVHCEVDLGEVMMDYDESWINYNQLWKSLLAHPGFAGKSFPERPSTDAWAAAMSGFNTVRGQHVVFSARFDQVPRAKKKGPMFSLSMQPIALDQGCRLHRHFGSDRFLEILIPNPKGWHEPIKEPEVSQEVVHWFSSKRHYLAGRQWRAFFSRDAGYKTPQKNLTMGPEPKPVYQDKISLFAENGNNFHAALPLGKSSHDNPREFRAKLSTGEMLDWLLQFEHNKEQPLLKLFSRIQLGLSKTTPVIVLEPNQIRHQKKDILSPTGMVMNDGIGLMSRALARKVRDVLGLSDVPSAVQARFGPAKGMWMTDVFGDDDSLWIETWPSQRKWNCDYVDPQHRTLEIRAHSMEPRSASLNVQFLPVLEDRAKDRDAMKHTIGKILENELYRSLEEQKNAMKYPLEFRKWNVENSSTRKQRLTCGRVPFLAGLPDSQEETMNFLLDGGFEPLKQKFLQEIAWNLRRSKCENLLKKMSIQVPNSAYFFMVVDMWNILEENEVHLCFSSKFQTETFSDSMLHGCDVLVARSPAHFVSDIQRVKAVFKPELHALKDVVIFSAKGNVPLADKLSGGDYDGDKAWVCWEPAIVSNFENAEVPPSPNLSSYLRKDKTTFGDLVQQQGEKAISEMIDRSIAFSMKPSYLGIVTAYKERLCYYLNSVNNHYALWLSALLGNLVDQAKQGFDFTEEDWYRFCRERLDSHQFNGLPEPAYKSECWSHPRSPVHIIDILRFVVAKPAIEKELAKFHKSMVTRSNESGYELRSLRSTKASEEELTAELWDPDLTKLHEAFGKHATKDPALKKILRNLKTDLEGAEKSWSEKVGSSKDKDDMNRAILEVYEEWRLIEPRPDGALEPLTDALLRQTYASEDHTTWALLRASTTFKMFYNRKTKFVWRMAGIQLQFIKAMTTAGPDRVLVPVVPSMYAALKPDAKFITQATSRLKDEGSEYPGFDSDGENDWDGSGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDW6</accession>
    <name>A0AAD8UDW6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_583897</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362161.1">
        <property type="nucleotide sequence ID" value="XM_060505710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDW6"/>
    <dbReference type="GeneID" id="85389609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000014">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="28694" checksum="A2C084B0DBE3CA4D" modified="2024-05-29" version="1">MSLVEQAKKAAAYRAVDEHLAPGARYVGIGSGSTVVYVVDAIAAKGPSFYGNMTFFPTGSQSKGLIRAAGLRLCNLDDRPLGPDGKLVAIDVAFDGADEVDAELNCIKGGGACLFQEKLVAIAAQKFVVVADYRKLSARLLTNWKAIPIEVLPMSAPDVLDRLTALGAVKPAVRPGAPGKAGEVVTDNGMWLIDAPFPQLLLSSDVSDGSARNASGAWEVSALAKELLMIPGIVEIGIFHGLNGVQAAAAGKVGLAQKPVAAYFGMEDGSVKVTGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDX3</accession>
    <name>A0AAD8UDX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_709400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359781.1">
        <property type="nucleotide sequence ID" value="XM_060511570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDX3"/>
    <dbReference type="GeneID" id="85395468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09001">
        <property type="entry name" value="GH43_FsAxh1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF15">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042088163" evidence="5">
        <location>
            <begin position="21"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="6">
        <location>
            <begin position="317"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1713728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56808" checksum="EDAC8C68B4F5A3BB" modified="2024-05-29" version="1">MRSWLRSLVTIAALAAPIVAETFTNPVIWEDLADNEVHRVGDTYYLTASTMHYSPGAPILRSKDLVNWEYVSHSVPVLDWNSHYDLADGKNAYVEGIWASSLRHRASNGLWYFVACVEFSKTYVYTSPDPAGPWTKAGTIDTCYYDVGLLFDDDDIPYVAYGNTAISVAQLSADGLTETRRETVFQTPSDIGALEGARMYKRDGNYYIFLTRPPDGQFVLKSSSPWGPYEVKVLADRIALNSVPNAGSPHQGSLVDTQNGDWYYMGFTDIYPGGRSPVLAPITWGDDGFPSLVTVNGAWGDYEYPLPRADVPSALRTDEFAGTSLRPEWEWNHNPDVSGIEVNNGITLRTVTVTSDLYSARNTLTHRIRGPIGTGTVHLNVANMADGDRVGLAALRDKSSWIGIEREGDVYSIVTVGGLTMNTDWTTNSTGEVVERRPLGDARDVYLKMVADIRPGGPGNVVFSYSVDGQTFETVGASFTRYNNWEFFMGYRYGIFNYATKALGGSARVSSFTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE05</accession>
    <name>A0AAD8UE05_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_437602</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362221.1">
        <property type="nucleotide sequence ID" value="XM_060503083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE05"/>
    <dbReference type="GeneID" id="85386982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="58189" checksum="0F97B23B7010DE83" modified="2024-05-29" version="1">MVRKGSPKVRTGCITCKARKVKCDEAKPICNRCTSTGRRCDGYRPARQGTISLHQPNQVFPGVTKVSEGRALQYFCEIAGPVMSGAVDPYFWTHVVMQFSNFEPAVRHAVISISSLYEEAQENFEATATVRHSNQNLALHHYNAAIHELRVMDSQEKQPIILLVCVLFICVEIMGANRKAALQHSRHGVEILKSISPDYMFSWTMEHLLPIFRRLSEFALFFGEEESDFPDIRALEGPMPQFFLTFSDAQLMLDVLFNRTAEFMRSQRNSQRAASKSPGPDETGTPPSSLLSEHAAINALLEQWFKLYNDFMAIKPKEAPTQSIQNSRSDSDRPKMLQCFLLTRYECCCIWLNMAFDTSEAGYDRYITNFRRILKRLLWLEAEVPDPLRFNTSKHPHFIFEAGFGAMLFFLVSSCRELETRLEFLRLMPVLGLPRENLWEADVLVAAARKIIELEHDIKLDTKGRPMSSPSLQMDDQGVSHRTIQVVRRDSKGQTYLQSENLVVNGRMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFH9</accession>
    <name>A0AAD8UFH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_43001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360576.1">
        <property type="nucleotide sequence ID" value="XM_060503041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFH9"/>
    <dbReference type="GeneID" id="85386940"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295124" evidence="1">
        <location>
            <begin position="17"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17450" checksum="3012B20761A7B845" modified="2024-05-29" version="1">MVVVHFLLALLRLTERHHHSQKLGHAAASHTASFQQPRKQVSTKHIRNSSQASSSNIQALESNSILAVPLLYAGTSSCRVIIGGWSKVSGQLASMKDGIVRYTPYMGVRNFCSQTTHRSALSHPCPELHFHCIVIVWQGRYIGMISLNDPRLAIQGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFY0</accession>
    <name>A0AAD8UFY0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="11">ARD'</shortName>
            <shortName evidence="11">Fe-ARD</shortName>
            <ecNumber evidence="11">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="11">ARD</shortName>
            <shortName evidence="11">Ni-ARD</shortName>
            <ecNumber evidence="11">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADI1</name>
        <name evidence="12" type="ORF">BDZ83DRAFT_629492</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="11"/>
    <dbReference type="EC" id="1.13.11.53" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFY0"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000079">
        <property type="entry name" value="1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="3 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="177" mass="20880" checksum="BCE7CEA8A3B10DB8" modified="2024-05-29" version="1">MKAYWYDGLDGDQRLAHDSGKEVTVEDLKKLGVFYHQIPDLDGVNQLASDRGYRNRDEIVVSPEKMGEIYEEKVKSFFHEHLHEDEEIRYVRDGQGFFDVRSADDAWVRIRVEKDDLIILPPGIYHRFTTDESNYIKAMRLFKDEPKWTPLNRTKDLDVNPHRKEYVEQYLQSGVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG66</accession>
    <name>A0AAD8UG66_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_62132</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360110.1">
        <property type="nucleotide sequence ID" value="XM_060508255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG66"/>
    <dbReference type="GeneID" id="85392154"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917185" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="18"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="172"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1714967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="40865" checksum="85C869CC28C2CE1A" modified="2024-05-29" version="1">MHLFTYNTTAVLLASAAAQSLGDVLAKHGSTSMLHGLLTNLKLMGTFEKAQNSTLLAMTDDAIIYLAKWGLNLTSMDPDIARGILQYHFLEGSYLSSAPAIHTETQLARSSLKPSSGLTNISKGAVVKLTATCDGSNSLRVESGDQKIIHTVETDIPHANGVIHTINQGLVLPRSLSETSSLGELDGFWNTVTKSGMDGEFEKLRDVTVFLPSNKAVWRGHSKLKSLDTEALETLIKDHAVPNHVLFHTCFPREPRMVTTLSGKKISISGDSKGRIFVNHKMVVMQNVLINGGIAHVVDELLSLEIDPDHDSSPGTIGAPWGLREDIARAVVGLTVISGVFIIGVIKAVRWRAAKRKAFLHYEPLPTTPSVVWVVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGH5</accession>
    <name>A0AAD8UGH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C6 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_655154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361101.1">
        <property type="nucleotide sequence ID" value="XM_060510781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGH5"/>
    <dbReference type="GeneID" id="85394680"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="43134" checksum="F3E72E85267E1093" modified="2024-05-29" version="1">MTADLLARGPSADGNPFINYVLPLAASDSLVMDCVLAIGGAHMAVLEPDRPQLEVMTRRHYARLLEGLRKALCDDTVCPFGERDEDKKLYTLLILIMLCIFEGVQGDNSGAVYHHIRASRHYVMDLAADTYKPSASKKTEHIRGFLLEIYAMFALKLSVTPRGLQEEIPVTLDPFLGSLEFLSRYKSRGFMIGFGHGLFAMMPEISNLLEKRRKEELSGSTSDGLLKSYKSLLEKLDSLDPSADVLEGQDACPRYQQSTAVTIYRTALILILHSAFHEDLYKNADLLAKIDLRIDKILPLCWAVYASKSPLRRMMLWPGSILASCCKKAEHIHAFRLGLNSNPRSPGGVREAAKAVELLWQDDDPNAFGPRGLNMVMKKHGLSFSMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGT6</accession>
    <name>A0AAD8UGT6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_586255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361069.1">
        <property type="nucleotide sequence ID" value="XM_060505930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGT6"/>
    <dbReference type="GeneID" id="85389829"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF8">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="316" mass="36129" checksum="B61FDEAFCDAB8A2F" modified="2024-05-29" version="1">MHSPMSSLDHWWWRFLENHVYRIPPPPKRKRTQPMQVLCVGPPRSATESLQQALLALGYDHTYHGWDIVYDDPPIPATGWVKLARKKWYGGGESSSPKRKGGKEIDDPSSEGDCQITAEEFDELLGHCVAVTDAAASCFAAEMIRAYPEAKVVLNVRRDLDSWHKSAVKTLVHVNESWSFWLSSLLDREAFWAWHVYERFLWALFFRAPDGDMAKAIRRNGKWVYREHCDMIRGLVPPDRLLEWSADEGWEPLCKFLGKEVPDVPFPHANAVGPGGGWKAREEMAIKRWIEGVLTNLILLGIFFVGGCAVWIKYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHD5</accession>
    <name>A0AAD8UHD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_456154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361679.1">
        <property type="nucleotide sequence ID" value="XM_060503193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHD5"/>
    <dbReference type="GeneID" id="85387092"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042065193" evidence="1">
        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="101" mass="11339" checksum="0956B04EA5B57C08" modified="2024-05-29" version="1">MSWRTVLLMGTLIGQMLSLDNSPFLHCEYADYPQQIWAEDARASRKTLCRKSQTDSWKFCNCRVTATFKILCTESGSLLHPSSGDRAFCGLVNCLGPGCWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHS6</accession>
    <name>A0AAD8UHS6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_702180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363463.1">
        <property type="nucleotide sequence ID" value="XM_060511453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHS6"/>
    <dbReference type="GeneID" id="85395351"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF110">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="2">
        <location>
            <begin position="80"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="29228" checksum="73E0ED899BEE8BC7" modified="2024-05-29" version="1">MATATKPNTAAGAAVYMPVLLRYIYDPVVLGFYCPKAWRITSRRMREFFNGHISRASARSQSPSLRRTSDTNAFSACRILDIGVGTGYFLKHAPIPAGSEVYLADLNPAALKAARERTLDAHPKTTCETSVADFLDPLGKGLCCKDLGGGDFDAISVMMLLHCVPGPPSNKAEALTRLRHLLAPGGTIFGMTILGRGVKHNLMGKHLMFWHNLLGVFGNTEDDVEGFVGPLMEVFEDVRWEVCGTMLLFEASKPRAQTRDTATSIHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI42</accession>
    <name>A0AAD8UI42_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_586117</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000103">
        <property type="protein sequence ID" value="KAK1718115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361115.1">
        <property type="nucleotide sequence ID" value="XM_060505914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI42"/>
    <dbReference type="GeneID" id="85389813"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001301">
        <property type="entry name" value="Structural maintenance of chromosomes 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="12">
        <location>
            <begin position="75"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="421"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="683"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="819"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="909"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1718115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1117" mass="127820" checksum="7BD4FBF0B7010F47" modified="2024-05-29" version="1">MPSHPSSRRRRRDIEDDDSEPCSDGSEGTKRPRLSRHANNSEDDDEHALPNGSRTNGSKSTSSRGDEDGFSPGAIRRVKVENFVTYELAEFFPGPNLNMVIGPNGTGKSSLVCAICLGLGFSPKHLGRAGNVKEFVKHGKPSAVIEIELQRRPEDRSHHVIRVQIDRERNSQKWWLNGKDSSHKAIQGLMRDLKIQVDNLCQFLPQDRVVEFASATPIDLLHETLRAAAPQQMLDWQKSLQDLHKDRKELQRGTDSAGDHLKQLEDRQNYMQHDVDRLREREEALQKIVDLTDARAVADYLESKALYKEKRQQEKLAQKNLRKLEHEAAPSLQAVNQKQVYHERVSAVVRSRKEALRRTEAAADVALNKIEDVDEQVKTIEGNIESSKKGFEFKKQELGKIRSKIGLLENQKKNKPAEFNATEHNTQIREKEHQLRELEAESRQAEGKLRDIKEQGHAKTHMKQALNRELEGLHSQQGQMLSFIQKKWPDVAKGYAWLQENADKFEKEVFGPPALCCSVKDERYSDQIQALLHNDDFLCFTAQTREDHKKLSHYLYKVMSLSVNVRSILKPLHEFRPKMSRDEANALGLDAFALDMITGPEPVLAMLCNEKKIDASGIALKDINDAQYDRIVQGEVINNWSTGRQLYRVSRRKDLGPGAVSTMTRGIQQGMFWTDQPVDEAEKSEIKRKISEVEAEFDALKAQNTEVRGQMAGFNDRRNEIHDDLKTLKERKNELQRAHNAYQAIPVKLESEKRALDQKKAEVEEARSAIQQLGFDIDKAAILKAKTTLKHHAAIAGVRAAQEALLEAQIREIEAKSDVQGLKARNNELVQMLEDEKRNIAALTQDSQRTRQRAEDAQGKVIEIFAQDETRKDLLESLAKDKSVEDVENEIAAEQHTIEQIHVANPGALREFEMRAREIEKLRAKMESTTAKLDHLNRQITKIREKWEPQLDELISKINDAFSYNFEQINCAGEIRVHKDEDFDQWALDIMVKFRENETLQQLNQHRQSGGERAVSTIFYLMALQSMAQSPFRVVDEINQGMDPRNERMVHERMVEIACREHTSQYFLITPKLLTGLRYDPRMRVLCIASGTHMPKEGKKLDFARCLKRHKQLTAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIM9</accession>
    <name>A0AAD8UIM9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tyrosinase</fullName>
            <ecNumber evidence="2">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_784477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362211.1">
        <property type="nucleotide sequence ID" value="XM_060515609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIM9"/>
    <dbReference type="GeneID" id="85399507"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="8">
        <location>
            <begin position="56"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="410" mass="46516" checksum="B9B00AA175A35100" modified="2024-05-29" version="1">MSKPRVRKDLATLNQDELDTLVRAFQHVISLKPDDKISYFTIAGYHGLPAPTAPGCSNLALPYWNEWSNESMEKRLPDLFTRKDYRFKDGSFVPNPLFFYKVRDSAIPLLWTGQCRLQHKDLGSQCRKLQRRRGKCGNCAKFKECLDAPNYTVFSNANSAQDWNKTRVRRGFHSVVVSLEEPHNSMHLAVEGFDVPSKLDDNVDVYPFANGDMGENDTAAFDPIFFFHRCSMDYMFWKCWISYLASKAQRGLDTPLEPFTKEKITPGDTRPMISNDVTNTADLGYGYPRLRGHFILPSPGFRKGPKLTASEINRARSRGSFVISTWAKGKNGQPDKLLDTKSDDEASDTDVYALVHTRDNPEGIDTIEGNKIQAELATTQQDIRAEARDQVVKTHTWLRKAQAVVGSIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ85</accession>
    <name>A0AAD8UJ85_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_721214</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362804.1">
        <property type="nucleotide sequence ID" value="XM_060512362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ85"/>
    <dbReference type="GeneID" id="85396260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="26"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="42501" checksum="5C14949ABF380E2C" modified="2024-05-29" version="1">MVDDRGTRLLAVTWSLCVASATLLSLRIYCKLWRGRGLWWDDHFLIASMVSLVISISINSYIVSLGFGRHIDTISSDNLKLINLNTILVATFGIIATTTSKSSFALTLYRIVTNQWLKYFLIFIIVSINISMNLVWIFGFAKCTPLQRVWDSSVPGSCWDKKKLVKFQLFAAYYSAILDFVLAFLPWPILMGATMRRRERLGVAVAMSLGAIAGICGIVKAVLVVNMTSPDITYERVDLTIWTLTEPAASIMAVSIPVLYVVSPIIKRMLYRELKSTQRSYARNKSQSHALDTGTRKEVRSTKRYGPGSQYGRNSVVVMSTGGWQESQEALQEAEGGQASPLPGMNGIIKTEEVRVRHERLTGLSEGESSIELDSLKEGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJM5</accession>
    <name>A0AAD8UJM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DNA repair protein rhp54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_619248</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365622.1">
        <property type="nucleotide sequence ID" value="XM_060508110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJM5"/>
    <dbReference type="GeneID" id="85392009"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000010">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013967">
        <property type="entry name" value="Rad54_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08658">
        <property type="entry name" value="Rad54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="230"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="563"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1725567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="802" mass="90648" checksum="64FE995075FD0F6D" modified="2024-05-29" version="1">MTVNVTATPIANKENVPSKRWPTPQSVDKLSRPFKCPGSATRTVATDRPARKKRRVDYKGADGDTDADKPYTNADRLALANRDANRFPVFQAKDKSTVFRKAFSVPLINKNTSAYNPNRPPPTLGLRTGAQFIAKPLHDPSGEFAIVLYDPTIDDKPKEPEKKEDKKDVEAETKIDAPLVHKSLAEILGIKKKVEGEHPRVPVVIDPRLAKVLRPHQVEGVKFMYRCVTGMIEEKANGCIMADEMGLGKTLQCITLLWTLLKQSPDAGKSTIQKAIVACPSSLVRNWANELVKWLGADAVTPFAIDGKASKEELTRQLRQWAIASGRSVTRPVIIVSYETLRLNVEELKHTKIGLMLCDEGHRLKNGDSQTFSALNNLNVTRRVILSGTPIQNDLSEYFSLISFANPDLLGTRLEFRKRFELPILRGRDADALESERKKGDECLSELLGIVNKFIIRRTNDILSKYLPVKYEHVVFCNLAPFQLDLYNYFITSPDIQALLRGKGSQPLKAINILKKLCNHPDLLNISDDLPGSENCFPEDYVPKEARGRDRDIKPWYSGKMQVLDRMLARIRQDTNDKIVLISNYTQTLDLFEKLCRNRAYGCLRLDGTMNVNKRQKLVDKFNNPDGDEFVFLLSSKAGGCGLNLIGANRLVLFDPDWNPAADQQALARVWRDGQKKDCFVYRFIATGTIEEKIFQRQSHKQSLSSCVVDSAEDVERHFSLDSLRELFQYRPGTKSDTHDTFKCKRCKPDGRQYMKSSAMLYGDTSTWNHFVNEGLKPIQDLLLRQECGEPEVSAVFQYISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK04</accession>
    <name>A0AAD8UK04_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="18">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_721033</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>7-dehydrodesmosterol + NADPH + H(+) = desmosterol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17737"/>
            <dbReference type="ChEBI" id="CHEBI:27910"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:46741"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>cholesterol + NADP(+) = 7-dehydrocholesterol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23984"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.21"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="21">
            <dbReference type="Rhea" id="RHEA:23986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Steroid biosynthesis; cholesterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 23">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="18"/>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362988.1">
        <property type="nucleotide sequence ID" value="XM_060512341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK04"/>
    <dbReference type="GeneID" id="85396239"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1630:FF:000004">
        <property type="entry name" value="7-dehydrocholesterol reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="5" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 23" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 23" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="12 23" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 23" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="17 23" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 23" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="16 23" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="406"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00039984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1722933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="469" mass="53103" checksum="8521387E1118C181" modified="2024-05-29" version="1">MESLDVPSAPESTFVRMRKGYCRSRLQLEPAQRPTWGRSSRGSWMRSVGSLLLVMLAPTLVISTTVTIFAFQGSLSDFLKATLQDGLISVVWSNWPCFSLKSTGVFALWILFQGILFRYLPGPIHDGQRSPAGHLLTYRTNGLNAWFVTHAFAAALCYFGLLDPAFIPKNWGGLVLTMNAAGLLLSVLAFIKAHLRPTHADDRKFSGSIFYDFYMGIEHNPRLWGDFDLKLFTNGRPGIIAWTLIDLSNIAYQYEIHGRIDPNIVLVTILHAVYVLDFFVNESWYLRTIDIAHDHFGFYLAWGSFVWLPSMYTIQTQFLGLYPARTSTFHQVAIFSIGVAGYIIFRAVNSQKDRVRRSNGDCSIWGSPAKVLVASYKTSDGQSHQSLLICSGWWGWSRHANYFGDLLLSTAMCALVGSSKCLVWFYAMFMTILLVHRCIRDEARCSAKYGPVWEDYCRTVPWRIVPGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK45</accession>
    <name>A0AAD8UK45_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_618611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365877.1">
        <property type="nucleotide sequence ID" value="XM_060508082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK45"/>
    <dbReference type="GeneID" id="85391981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000214">
        <property type="entry name" value="AMP deaminase Amd1, putative (AFU_orthologue AFUA_8G02860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="276"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="945"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="985"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1024" mass="113728" checksum="8A5DEF2BCD941826" modified="2024-05-29" version="1">MNQKDPTSASTSPKRGPAFSLHDGDTDSDGELGALDSRGDNSSEGSGGQTPGDAPASDANPLSPHGQDHDGASLQDGMLPRDLPTRTAFYDPVADRQMSQTDAKLFYQRSQVGQLKTGSGVWSQGHATPHGSPVIVGSEHRDVPAGTRNLDHPMDSSPLGKAHGQVRGKAPAHEEMMLPEPTQLQQQQQAASAEHFSPPRNHPVHEDDPRFPNSEFNNLGLGHETGPSVSATNQPATLGVAAFSDTDPHITAELSAISKNIQSIMDLRERYVGLSLQRPDDNPRDDPTWSIYPPPPQPAWGAEHARAVASAEQTTSNANSLNGSMVLPSSATAASDHTSRRAQDSEAKPTSKKRKPGQDIGEDFDMQDLLPVPSADKMTFKLDDSGVYQVFDDAESEARGNPVIRVPTIREFYMDLDQILSISSDGPSKSFAFRRLQYLEGKFNLYALLNEYQETADSKKVPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKMKKCPDEVVLFRDDRHLTLAEVFQSINLTAYDLSIDTLDMHAHTDSFHRFDKFNLKYNPIGESRLRTIFLKTDNFINGRYLAEITKEVIADLESSKYQMVEWRISIYGKSLDEWDKLAAWVVDNKLFSHNVRWLIQIPRLYDVYKASGLMDTFEQVVKNVFEPLFEVSRDPSSHPKLHIFLQRVIGFDSVDDESKIERRLFKKFPVPKVWDSKQNPPYSYWLYYLFSNMSSLNALRQRRGFNTFVLRPHCGEAGDSEHLAVALLCCHSISHGLLLRKVPLLQYIFYLEQIGIAMSPLSNNALFLAYERNPFYQYFRRGLNVSLSTDDPLQFAFTKEPLMEEYAVAAQIYKLSPVDMCELAKNSVKQSGFESAIKEQWLGPNFKLPGKAGNAMVKTNVPDRREEFRYQTLREEHDMLHKYINYGANETPDSAVTADQQSVAQSIIGGHHPAVQREPASAGVDSAPGNGGGTQTAVVGGSNSAAVLEEDVVASPASLAPSGEASWSTDGHTSGRDPKLFPGVVSRGRTGSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKB9</accession>
    <name>A0AAD8UKB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_279104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365952.1">
        <property type="nucleotide sequence ID" value="XM_060502119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKB9"/>
    <dbReference type="GeneID" id="85386018"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF81">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="672" mass="73520" checksum="3A53EA3605A8DF45" modified="2024-05-29" version="1">MAPKNHLPHPQPQPFTPSSASTAYASPVPEHGRLPSLTHPQNGGAAATVAALSPTASAASGPSYSTPVARQQTATPKSYGNGNGNGTHHQHPDESVDGNSASPDDGGDKGPARKKQKRNKPTLSCFECVERKTKCDRGRPNCLACIKRQTECQYAAVATILEETTRSLANGRRMTKPPKPKGPGDISTIPNVADRGLIEGRGFTSRGSVGSVAFSSSTGLLSNVPYSLPTASNVFGIGSEHPFANYWTCEGGLPEVISVLPEKVQADILLAQYFECVDPVYPMIHRQTFYADYEHFWSLSAEEKNRVDAAFVGLIFVMLALGTQFVTSSSPNDAKQTAEFYASASNQALRMFSYLSAASLRSIQSMVLLTYFLINDNHASDGWAFAGILIRQAYAMGLHRDPNIVTPDAPIFEKQQRRKLWQAVLLQDTFLTVLLSLPPSATHTDVSVEDLVDDGSAIASSDPTDIAYIRGSWTLANLVQETICSPRSLDLPICATVRHKSKLIADFRCVYRSFPDVFRSWDAESLASLARTNKRVVRQTLFLTSNYHHNIMLVYASESAECPSNTRGTLEAAHEAITSFFLLFDIFELEARVWWVFNHRAFLEALCIGSVLREMGKDPVAAEEADRDPLFQRARSDIGELFDPLILSFSLFSTIILYFSILSLLGFTSGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKW4</accession>
    <name>A0AAD8UKW4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_720400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363870.1">
        <property type="nucleotide sequence ID" value="XM_060512268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKW4"/>
    <dbReference type="GeneID" id="85396166"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019433">
        <property type="entry name" value="GPI_ManTrfase_II_coact_Pga1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28022:SF1">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2 SUBUNIT PGA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042010912" evidence="2">
        <location>
            <begin position="21"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="26642" checksum="DDB68095B2381D6E" modified="2024-05-29" version="1">MRLAFAVSLALACCLNVVRANTEKVIFLGPETVNVPVTPPTIQDLRLDVLTPDDWSKRVQLPASFPTSESPLGTTSWLLLPNLTQGQRYELRVCWSATQPTAFTLDVFELPVVWDTPELISSLATYAFSRQSNQDDVGAHQALQSRGREHQSSLLFLRVSASADYFTDNDTLMAKVEPVSVDLILDPFLFNVLPRSLVPTVAYIVLVALSAWFLSKRILAWIQPVLANEGRSTEKKKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULA6</accession>
    <name>A0AAD8ULA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752113</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364982.1">
        <property type="nucleotide sequence ID" value="XM_060514149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULA6"/>
    <dbReference type="GeneID" id="85398047"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="39339" checksum="3D710EFAB5B725C5" modified="2024-05-29" version="1">MPPRGSSSRGRGRGRGVKATGGAGKRKRDPDDAAELDGIQKQRKTKNKDSMMEDREWTNQYYQGVSITDLHGRGYGHCHLITPRVPFSSPFACDGSIEVMSGSGAPGDGSVRLVGPRDYFGKSKEQVVLLANAAKPPSKKAAYEVVVIPTGATGASSIKREYPQIISFIWPEKKADKELSGILAKDEKGTYVDVLKKVFKEQLKAFDKSVIDTTEDPDANFAGVGCVLSPPMGSNIKSDIDGTVHFLDHGVLFISEIHRIFLPFKSLDRVMLVHAKDSKGKLVGLDVVCNVIEPFHEDKEEESSGTTMIKIGQVDDALFKDLKEYMEENDLQVMVCEQSFYDYKKGKSMTGFMPMMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULF9</accession>
    <name>A0AAD8ULF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_580669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363561.1">
        <property type="nucleotide sequence ID" value="XM_060505371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULF9"/>
    <dbReference type="GeneID" id="85389270"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="853" mass="95228" checksum="F570214182D6CF22" modified="2024-05-29" version="1">MALWPFRRRSGRKRSRSGANLSDVEAPPISSLQARGHMAGEVTAPRAAMPKKQRLEKQQRLEKQQPAPRRERTYSFSPGRNDSIRVAGQKGSVPLGPGRSTGLFPADRNDGEEKGDPAWQRAPTLHNARHGQPSRSSRRKTSKRRREETDREAEIKAMANFAPVRPAADPWTSGRPIRKQSKRLKTGLGFRRSFENPQSDVSLPISIHSSMSSDTELHSFRVSALEALSPRPTLRYAVYPRWGPGHGSVPSRTQQQKRKVSERVPESVVRAHKRVDSFADDLDAADLRELMERDNRRRERKRQRDQERIERRLARRSEKQREAVAEARHSGSPPPVNLERGVLGRELGLGIDAASAVVTSSRRRSWSSSRHSRKISTTKDSEPEQEQGQGQESEREPQSETMDIEPEPAAIQHFHRTTSIPPEAPPSPTLPAQPVPERKTSTKLTPKASMRLKRSFLRRISRSRSPNATESDQHAISQYSSRQDEGETPRKDSRARISFSALFRLGKRNRRNSGPSSFSNTSRETMQASAAAAQIYSQSATHVPQQQEEAAAAPVQVPTPAIPPPVNYIPRKVSNGVPKRTRSRFREDLPELPLSPPDSRVGSPEVEMPLPVVSESKSGEISQQDTPAVRHDTPTSDLRRVDEKMEKLEKMRQTPTSLRHSIQPSPEPVSLASIDSEGSWLSGRVGARRSSGMRGSMQRLPPQNMSHSASPNDTEEELADDEYLSNLATPSREMLADEERTPRKSTGDAFPSSDEDEVMEDADMKWGSVDRQRATVVQHQRVKSREGMLKSYGEDSTSSPDGSEEGETPQLQRATSVSLSRGNARHVSAGSTKMLEVSPRSSVDHRRSTDAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULU2</accession>
    <name>A0AAD8ULU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">CFEM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_718408</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366717.1">
        <property type="nucleotide sequence ID" value="XM_060512070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULU2"/>
    <dbReference type="GeneID" id="85395968"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009769" evidence="17">
        <location>
            <begin position="20"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="27"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1726662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="450" mass="50585" checksum="DDB78BC73D4EA459" modified="2024-05-29" version="1">MKPYLIFLSFLASLPLVYGLYDDVPDCALPCLFEPLDYTACQFSNSTCLCEDMNYNMAVIHCVRIQCSVQQALITKNRTWQDCGFAYHDEEVSIAWVPSFLFGMVTLFFAMRLATKWIGLATWGLDDTTITFAYVMMIAFLVATHLGRQEGFGKDIWTLTVDQITNFIRGFFAFEIVYSVTLAVIKASILFLYLRIFGALTETFRRILWATHAFNVVVCVTFVIVNLNQCKPLSYFWFGWDGRHPGYCIDLSAMALSHAAINIALDLWMLVLPATQIYKLNLQKRQKAGIMSMFGVGIFITIVSCVRLRSVAQFNKSWNPTYDFFGLALWSHIELCVGTIVACMPAARALVRRLFPELLYVTNISTNRTSTRASGNVKIVSQDIATIATDDIPESSTTNSTKKDSLATLIPDRVPLRRLTTSDSLLQVSHSDIDRSSNGGSQKGSKLSDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM79</accession>
    <name>A0AAD8UM79_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_385524</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. RimJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363694.1">
        <property type="nucleotide sequence ID" value="XM_060502738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM79"/>
    <dbReference type="GeneID" id="85386637"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF8">
        <property type="entry name" value="[RIBOSOMAL PROTEIN US5]-ALANINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="21916" checksum="47B01FA472D42C67" modified="2024-05-29" version="1">MSATKDLPPAILTLTKATIRPYHKTDAPALSTAANSPSVSRYLRDSFPRPYTLADAESWIAMNSSDGGAPVYNWIIACPETGRPMGSIGLVPGKDVYARGYELGYWLGEEDWGKGVMGCVVPAFVRWVFEGMGGGEEDEDRKTEVERVWAGVFEANEGSQKVLEKSGFVFEGRARRAVVRDGIVMDELLYSVIRDDLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM93</accession>
    <name>A0AAD8UM93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364454.1">
        <property type="nucleotide sequence ID" value="XM_060514225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM93"/>
    <dbReference type="GeneID" id="85398123"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042141743" evidence="2">
        <location>
            <begin position="20"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="20975" checksum="F97829871DFEA3A4" modified="2024-05-29" version="1">MRVQTFASLGAVLTTAVKAFTPLNITALSTRDGYSVIECWQLTSVPFEARAALNYAVGGDLTRAEWSIIQPRTTVGEAWAPAVQLTVILNGLIRITSPAPPRNASQATPSPLSPGGSSGDDASAAPPAQRTAYIQPGTVSSSLVIAADLKNASVHAGHFTEFPGDEPTVLVQVPFAGNAAPEHVVLGEGPCERGSWGAAMGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMA5</accession>
    <name>A0AAD8UMA5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_575447</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366043.1">
        <property type="nucleotide sequence ID" value="XM_060504816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMA5"/>
    <dbReference type="GeneID" id="85388715"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041931746" evidence="8">
        <location>
            <begin position="19"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="146"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="10">
        <location>
            <begin position="610"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="924" mass="98919" checksum="3ADF43D88121B3C4" modified="2024-05-29" version="1">MRVASALISVLALAGAGAARVSRRAVDKDARPSNDTAVAPKKFIVELEQGADKDAVVQQLQTNNPGSKILKVFDSFLFNGIAVESDSENTDSLEAIVPVVKAWHSTRIQLAPVVSGESFSDDARALNYSIHWMTGVDKLHEQGIFGKGVKVGVVDTGTEYTHPALGGCFGEGCKVAAGYDFVGDETNWPYPGAERQPDEDPMDQAGHGTHVAGIIAGKSSEFTGVAPEATIYSYKVFGPNEGTAEEVLIEAFLRAYDDGVDIITASVGSTGGWSDNAWALVASRIVEQGVVVTIAAGNSGDVGPFFPSSGAAGKDVLAIGSADASIVSARQFAGTFTLGGQSNRTILGYRPAEELFPAEINGWPIVPVTLNISVENDACSPLPEGLNFTNTIPLVRFDEGCQDHIRQRWVQERGARFMLFYLTDRPVVGFSGSGWAQSKWGLLSKDAGEAIVKTVIAGGNVTADFSLDQNSNYVAMYNAGGGKPSQFTSWGGTFDLELKPDVTAPGGRIFAPFIGHRYRDLSGTSMACPYVAGVAALYISARGGRSVHGAGFAKALHARIVASGRAIPWSDGTTKDFGFWAPPIQVGSGLIDAVSVLNATSQLSGETKFALNDTHHFSRYHQVDVTNTGPTELEYIFTVQDAAGFEAYWTAEAADAGISAVPRIKDLVEIEPVKIGAVVGLPTGGFKVGPGQTKTAKFSFDIPQGLNASRLPVFSGKILIGSSAGDVLSVPYYGVGGSIKHDIADLFYTSYGYPRVSSGVNRTLLSEKSSFTFDTSLAKQDFVRLQVALTWGSRQVRWDVYEPTYQEREWVYPPVVGENKYVGSVASFDVYNSVNYPVFDPATDSVNNTFSYPLQDQSRDSPYESWWLGKLADGSQIKPGKYKWRIAALKAFGNPKASDNWEIFETPVIEVLPLAGSNSTALRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMH9</accession>
    <name>A0AAD8UMH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_578997</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364323.1">
        <property type="nucleotide sequence ID" value="XM_060505190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMH9"/>
    <dbReference type="GeneID" id="85389089"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF2">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="567" mass="62799" checksum="EB3C5C8CA019A87E" modified="2024-05-29" version="1">MDQQYLTSPTSFRLADIAQNVYEMPLMAMKKPHDSHPSMGNLVLLVFEAVLEVVCVSLPGYIIARLGHFDAEKQKFLANLNVMLFTPCLIFTKLASQLNADKLLDLAVIPIIFIIQTLVSWLVATGVARGFGFNRRATNFVTAMGVFGNSNSLPISMILSLSQTIKGLHWDKIPGDNDDEVGARGILYLLIFQQLGQLVRWSWGYHVLLAPKDKYPEYQDERVEEGQYPGDRETAPLLNEYDDGTATSRSHSSDDLSNYEPAGRTPVASRSRASPADTEDEDDDYLPKKPMKTNGLAPLNGNHPVFDGSGDEISSFPRIRNTDEPEIPEGVKGYPSRIKNAFNNTVTSAKQSTSNFFARVYNSLPAPFKTILSALSRFASKFYNFLWEFMNPPLWAMLSAVVVASVPALQKIFFEEGSFIKNSFTDAVQSSGGVAVPLILVVLGANLARNTQKSEKMRDPEEDQIGTKLLVASLVCRMLLPTLIMTPILAVFAKYVPVSILDDPIFVIVCFLLTGAPSALQLAQICQINEVYESVMSRILFQSYVIWILPSTLVLVMCALEVVEWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMV8</accession>
    <name>A0AAD8UMV8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_699493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364920.1">
        <property type="nucleotide sequence ID" value="XM_060511413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMV8"/>
    <dbReference type="GeneID" id="85395311"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042013716" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="43855" checksum="C4D9455E0E8BA7B1" modified="2024-05-29" version="1">MKVSSVLSSAALASVALAAPSVKPRGDSTTDGAQFADLTASIQANVVKSLEEREARLKKRGESANCTTSNMVFRREYGSLSLTERLSYVNAVKCLQSLPPRTPANVSSGARSRFDDFVVTHIQQTMTIHYTGNFMPWHRWFVHLYEKALREECGYTGYQPYWDWPKYASAPELSPIFNGDPYSLGGNGEYTPHDGPVIEPPEGIGGSSIQLPAGVGGGFVTTGPFANMSVNLGPVGGLEGTAPGPDGGLGYNPRALKRDVGPAMNQRYANYTTVLNLLLKPNISEYRLLSEGVPYTPEIGPHGGMHYAISGDPGADLFTSPGDPAFWVHHGMMDRMWTFWQALDPAARQQELNGGDYGHITWANNPPSVKTQLTDVIDMGYTGPSIKIADVMDTLSGPFCYFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW9</accession>
    <name>A0AAD8UMW9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_739493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367332.1">
        <property type="nucleotide sequence ID" value="XM_060513044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW9"/>
    <dbReference type="GeneID" id="85396942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045030">
        <property type="entry name" value="LYSM1-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932">
        <property type="entry name" value="LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20932:SF31">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="277" mass="29758" checksum="8C3E8ACA1BE8BD24" modified="2024-05-29" version="1">MGPVRACCTCAKLLSSVPRYSAATEKPLPDDRRLGCCARVICGNCIHENTRFASYCPYCQTSTAPSVLPPNLKDPPSYTSFPPTHHLSSGAPAAPPPPYTYTSPDAGADEELNEKSSGSSSSTATPPEDTLHFLNHDTDTIASLSLRYGVPAAVLRRSNNITSDHLLHGRRTVLVPGAYYAAGVSLSPRPVEGEEEELRKSRIRRFMTGCKVSDYDVAVLYLEQVGYDLAAAMEAYADDEAWEKSHPVQDGGGGGGRGKNKAKAAPRNRGPFWRGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNH5</accession>
    <name>A0AAD8UNH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_751892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365340.1">
        <property type="nucleotide sequence ID" value="XM_060514117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNH5"/>
    <dbReference type="GeneID" id="85398015"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="57467" checksum="20ADE35F6F8258E6" modified="2024-05-29" version="1">MAASTTSAHFVNVYQSVDKTKRPVTTSLAVARSPRSPSGDTEEIKATLPEYYTAPPWRLLWDDLVLFIRCIGFIPFVISPLWYPRRDGVRYPKLDKSWMPRWLLWGPIDSAISAIQTWYQGKVDPYYPSGEMDELYPSVGNLWCLFIHGILIVTQLAFLISLPFLATLPFQLFVLYIGGFIFVNYIFCLQLNAGTENNLLKSQHALWPEAANWKSLDPNENYSEEWIFLNGVSVGSHWLQGNINRLSRTFQRPITGVHNRTSGIIFDLIQCLLERCFYFGTSDTRTCYALITAALDPAQKKDKTVLILHSQGGLEGSIILDWLLSNYRRETLHKLEIYTFGNAANHFNDPETSKNEHVIGHIEHYGNTGDFVSQWGVIHFKSLVAEQSNPQPMDGRHPFLPIVDDILRLDKRQNTFAGLLFENNVLGHLLNQHYLDRLFPLNETLTRVVESKGKPLMETFMARTMRAGNGSCDVEGHKVCQKSRLWEYINGKKPKEYELQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNZ1</accession>
    <name>A0AAD8UNZ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ran-interacting Mog1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_751643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365655.1">
        <property type="nucleotide sequence ID" value="XM_060514081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNZ1"/>
    <dbReference type="GeneID" id="85397979"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="21986" checksum="0DFC587B3ACAEB3A" modified="2024-05-29" version="1">MTRYKSTPLYGGALVSDLPDKFADVSKLREVPDNQEVWIDSDGFTSIIFDITERVGPAGSSPEIDGRALTTHLEELVGEDVDTVKVWNTTETSFSRLSSDIPAYTLIATQTPHASKSSRSSSSSAPDFTAIILTLVRLEKESTDILVTINVPHIKGEYDEADVDLELGKQGKLIGDAVEYAARIWETFKVKDWTLFQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP64</accession>
    <name>A0AAD8UP64_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7872 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_750939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366392.1">
        <property type="nucleotide sequence ID" value="XM_060513986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP64"/>
    <dbReference type="GeneID" id="85397884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057194">
        <property type="entry name" value="DUF7872"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33339">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33339:SF1">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25278">
        <property type="entry name" value="DUF7872"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167009" description="DUF7872 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7872" evidence="2">
        <location>
            <begin position="189"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="400" mass="43638" checksum="DADB50B49A726732" modified="2024-05-29" version="1">MRANSILLALAYTGAFATPVPQDTGSADCKTEALNQDTWKKLDIENFLADWTTFNVSKVEHNAVQNFANSFGAPNFFCGLDSFCNAGQPCSPVKLPGWYALVAVQNWNSYMNSLNTAITFASSILSLTLPGIVQDFYPNPKDDITDLKTMTRVFAGVLSIIPFTGPLSTVAGAVGSTSSFVSTNLKAPEPTNLFLSWSNVATSLGKVVQNWQSAVSSSFQTTIDAQVNVTGGIFQIIRDGKFLGTSRNITQGDMQKEMTRSLELYTIGLALQAQKVFVLRSQPFAEKCTEYTEAELCSQDADGRWRQYILIQRSDHKNSIGRKDLMKLLTEKYQLKKETVTKEVAECVDAAGGKQLTYPFGDILPVDSTAKCIFNLQVCTTPPGAREGIITTCEGLGLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPU9</accession>
    <name>A0AAD8UPU9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proteasome component PUP3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_750609</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366737.1">
        <property type="nucleotide sequence ID" value="XM_060513939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPU9"/>
    <dbReference type="GeneID" id="85397837"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000003">
        <property type="entry name" value="Proteasome subunit beta type-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="191" mass="21138" checksum="2FD6B81EAD87D070" modified="2024-05-29" version="1">MVGKDCVAIACDLRLGLQALTVSNNFPKIFQYGDVFLGLTGLATDVTTVGDLFRYKVNMYRLREERNIAPTTFANLVSSSLYERRFGPYFVSPVVAGLDPKTGKPFICGFDSIGCIDFAKDFIVSGTASEQLFGMCESLWEPDLGPDELFETISQSLLNAVDRDALSGWGAHVYIIEKDKVTKRLLKGRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ9</accession>
    <name>A0AAD8URJ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_577221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365180.1">
        <property type="nucleotide sequence ID" value="XM_060504997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ9"/>
    <dbReference type="GeneID" id="85388896"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF20">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="87"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="57824" checksum="5D17461884B15885" modified="2024-05-29" version="1">MDKDLRQPEPTSNDKGSSELAFARADAETGGSSGFSAWFGGRNTKVGPRIAPRKEGVGEGSDSEDSADAILTKQLAEENSHAIKYRTCSWQKTAGLLFSEYICLAIMSFPWSYSILGLVPGLILTAVIALVVLYTSLVLWQFCMRHPEVRDVCDIGQMLFWGKTWAWYATAVMFILNNTFIQALHVLVGAKYLNTMTESDPVVCRTVVFSIVVTIICWLCSLPRTFDALSKAGTASAAFTFISVLLATIFAGIQAHPAGYDPRSTYVDETTGTTKTGGAPIVTAIPIAATTFVSGMNAFLNISYTFIGQITLPSFIAEMKDPRDFPKALWAVTIGEIIVFSIVGAVVYAFVGNQYMTAPAFGSLEEVYKKVSFSFMIPTLVFLGVLYASVSARFLFFRLFKGTKHLHEHTIVGWGSWATILLALWLLAFLIAELIPFFSSLLSLMSSLFDSFFGFIFWGVAYFRMRGADNRAGVPKPGKLADLATMGLNIIIILTGLLFLTAGTYASVEGIIEEFRAGTVGKPFGCASNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USW2</accession>
    <name>A0AAD8USW2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_740118</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21. Interacts with preproteins in transit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion inner membrane</location>
            <topology evidence="1 15">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366574.1">
        <property type="nucleotide sequence ID" value="XM_060513057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USW2"/>
    <dbReference type="GeneID" id="85396955"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000019">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="17">
        <location>
            <begin position="255"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="20"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00063960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1726519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="547" mass="61209" checksum="3C0FFFC8FED10427" modified="2024-05-29" version="1">MLSRAARIARLQPTAAQLYRSVATPATRRPQFLASSWTRGFAQDNKPRGSSSDKPIDQQKSSQSTPEETSASSSPEYKAAYEEAAEASSKTSSTQTPKSDAENAADQTEAPEPAAPTGPLPDLTQGIPSTLAYEMSGAANKAALAALAEEEAVAQGGGRGRGELPDSAYVSSTDRKRQQFASRMFLAFVGFGAAGAVYLGRNWEDKADELRHAEDAPNGWGFGAWWNRVTARTGDFLNYYQEPAFEKLLPDPDPSFERPYTLCISLEDMLVHSEWTREHGWRVAKRPGVDYFLRYLSQYYELVLFTSVPFAIGEPLVRKLDPYRFIMWPLYREATKYKDGEVVKDLSYLNRDLSKVIIIDSSDKHVQNQPENAIVLPKWKGESKDKELVSLIPFLEYIHTMQYGDVRKVLKSFEGKHIPTEFARREAIARAEFNKQVEAKKKKAPSGMGLLGGMLGLKPSNMALMVSPDGEQNPHEALAQGKMLQDIARERGQRNYEMLEKEIRENGEKWLKEEAAMQEKAQQEAMQSMMGSFSGWFVKGDEANKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT12</accession>
    <name>A0AAD8UT12_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_574260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366649.1">
        <property type="nucleotide sequence ID" value="XM_060504696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT12"/>
    <dbReference type="GeneID" id="85388595"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000007">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="24613" checksum="2DD646AA8E22A7FE" modified="2024-05-29" version="1">MANLPTTKSIPGKETPGLRYPSNGKTIYHRPLNRTKTAELSQSSFAYLFSEMVSYAQRNVKDISELEQRLNIQGHSIGLKLLDLLLFREPPRTQTRPLTIITLLHFIKQSCWQHLFGRQADRLEKSADPAKPDEYMIIDNEPLVNAYISVPREMSQLNCAAYVAGIVEGICDGAGFPARVSAHNIAAKDEHEMWPGKTVFLVKFRPEVLEREGYLGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTP9</accession>
    <name>A0AAD8UTP9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Subtilase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_728193</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368370.1">
        <property type="nucleotide sequence ID" value="XM_060512799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTP9"/>
    <dbReference type="GeneID" id="85396697"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077515" description="Subtilase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="158"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="12">
        <location>
            <begin position="556"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="834"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1728315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1031" mass="109128" checksum="F133A31A51E69CF9" modified="2024-05-29" version="1">MEIKSLLALASFIFCGEVLAQTSSDDPEAILGPVSPISIESGRYIVKFSSSGSAKFRKRDGDLDTAGFFTTLQDAGKDASPAVSFNSQLFHGASFDLKNDTSETVADIQALPEVEKIWSAALFSLPITTEAVVQTEFPTWNPHNDTNVALAHANGHFGEGVVVAIVDSGIDYNHPALGGGFGSGFKVESGYDFVGDNYEPGDVYLPDEDPIDCNGHGTHVAGIVASSNEFVPGVAPSARLRAYKVFGCGGSTYEDVIVAGFLRAHEEGADVVSASLGSNRGFVDTPLAVVATAIQAAGTFVSIAAGNAGESNNGVQWSLNGTAPASWAPNPRDHADQCGIDFTIPDTNVLVLPGLMEKVDWVLIYNYNGSDWEIPGRVRYDADRQAKGYSLITYEDGDWLVSQHERNYTVTFEFVNDDKPAAIDRPSFAGGRIDQFTSWGPTLDARMVPQISAPGGSIFSTFPIGSGSWATLSGTSMATPYISGVAALFFSSRGGRAALGDGGAKLAHEVIVSSGKPIRHYDGTDNLASVIHQGAGLVDAFKVVGYSTLVSPAVLNLNDTEHFQGTQSVQITNSGDESVTYQFSHEAGITALTKSAGTAWVSVSPPYVSGDGNTATVEFSPAELTLGPGESGSVSIAFTQPSSPEAATLPVYGGSIVVAGSQGEAVRVSYMGIKGSLYSSDIWEMERGVPLLLSGYGGLIEEGHNYTFEEGGDVPQPYFNVLWSTQEISFDYVARDWNETDWAYPAVPGQAKYHGSFITVPQGLSDSITSFPLRNYPRNSGGVYAPPQNVFAHGGDIPAGEYRILCRALRTFGNPNNLNDWQYKVSPWFRTTREKPPVTATPTTAEATPAPTTSSVSLPEPCAATSTPVSIEATLASGEGPYNLYLYADFASIDLTGSQTPLNFSITNSTQVQTWFNSSWRFLSVHTNTNSLIYVYASSRVTGAFSFLGCTVTNDVLGCESNGKSALYVCDSTTGLLRHGTQPLDGCQTVTLKVGPRENPNCAATTTSVTATEITAAPTTLSTAVVSVSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUF7</accession>
    <name>A0AAD8UUF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_169433</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Vacuole membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368028.1">
        <property type="nucleotide sequence ID" value="XM_060501457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUF7"/>
    <dbReference type="GeneID" id="85385356"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000001">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="22"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1727973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="171" mass="17810" checksum="F4B06C023459797C" modified="2024-05-29" version="1">MDEIVFANLDRCPSYSSFFGAMGCISAIVFTVLGSSYGTAKSSAAIFSAGILRPDRLMQNTLCAIMAQILSIYGLVAAVIIANRLAEKQALHTSFLQFAAGISVGLCGLAAGFAIGIVGDAGVRATNQQPRLYTGMVLILIFAEVLGLYGLIVSILLLSTSQTQVTDCSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUN6</accession>
    <name>A0AAD8UUN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF2 family N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_610245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368163.1">
        <property type="nucleotide sequence ID" value="XM_060507580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUN6"/>
    <dbReference type="GeneID" id="85391479"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="230"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="602"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="532"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="769" mass="86956" checksum="81143ACBB4DCE95A" modified="2024-05-29" version="1">MLTSLSAQWMTDIERTPATNVHLILDNEWQLVSSTHPEFRAALDPRGRELLELFHREGISIDILGLTAEQKDVDDDRIQLWITLYGLREIAQGVGGALQEAELYLQDPAFSLTDVEYFNPQRFTNPDGSRTADFRTVLSDEDEVSAGMDETLMAIDVLKSVTSTTVRFETNGSYYLQTELQSHQKQGLTFMLERERGWRLQEPNGDVWSQHVDDFGRKTYINNVNSSFRCAPPAPFKGGILADFMGLGKTLSMISLIAHDKLWESGSQYVRQEPNSLGSGGTLIVVPLSLLDNWEKELTKHLLGDHFNWRRHHAKTQLKDVCHLSTSDIILTTYTTLSKEWKVHVQTNESPIFSHEWHRIILDEAHEIKDLRTAKAQAICELRGDCKWVVTGTPIQNRLSELHSFFHFLGLHPYDDKKAFDRDITNPWLRGEETGPEALKKILGYVMLRRSQDTITLPERRDHRRHLYLSPQEQRMYDAVKIKTIEFIDNALASPRSNDNYSNALEKINALRLVCELGCFQKLNLQQKPASYAGLLPGRPDRQSTPLTPGREREEDEDIQNGNIAEAIDNFCPPLPNLGFNWTQEPSGMLCGSMPTDQWPTKIKALVNDIKCCVPGTKSIVFSYRTSILDVAELALNDAGICCAKIDGKKSLTKRSRIIDDFSKADGSSVLLLSLGCGAVGLTLTAASRAYLLEPQWNPSIEEQALARIHRIGQTQEVTTIRFVISNSIEQYVLDIQNGKRDLMSLLSSKPATSQQLTAKLQQLRQLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X963</accession>
    <name>A0AAD8X963_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_735427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358732.1">
        <property type="nucleotide sequence ID" value="XM_060512966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X963"/>
    <dbReference type="GeneID" id="85396864"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="14"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="390" mass="42736" checksum="2503756300CAAEDD" modified="2024-05-29" version="1">MSTSFQSLAVAETRPDADGVTGLAVFATDSSGNQFIEEYFGRSSTIKSDKIGKDSVFWIYSITKTITAIAALQCVERGQIKLDDEVYDVLPELKDFQVLGHDQAGNVTLHPHKKKITLRHLLSHTNGIGVDVFDPRLQAWRMSRGEHPQAFSGDSKKAYTIPLLFEPGHGWAYGGGVEWAGILVERLNKMKLGEYMKANIFDRLGMASTTFHPDRDPTIKERLVETSTRISDGTLVPMEGPYPAVTEDDSGAMGLVSSVPDLTKLTTDLLQTEPTILSEESLKELFSPQFSADSSSAGMLAYGAMMYGRLTGEEYDPSKVGQAPGAYFIKKDTRILPGGTLVMTGIPNLVWFVNRKKGIGGFYASAIMPPDDAKSTKLIQEFLKEVFSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9L3</accession>
    <name>A0AAD8X9L3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_724483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358166.1">
        <property type="nucleotide sequence ID" value="XM_060512660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9L3"/>
    <dbReference type="GeneID" id="85396558"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="205" mass="23292" checksum="A03AB3F8769D339E" modified="2024-05-29" version="1">MVLLTSSQVSVLISSAIVVSCTAALFLSGYVIQQRTLNQLREAIKPESRPSPKASYYVPEHLKDAGAGNGQNVPLYGVANGKQEQIIIEVNPTVPEKQQQEQPQQQSKKQQAGKKAAGWTSDMWQKMMGPSEKEDQGGVSREDLEKMDERERNINGWNVKDQANPDPEASNQKPISRAERRRLIKEELRRLSESEERVYYQRRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9R2</accession>
    <name>A0AAD8X9R2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_637390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359754.1">
        <property type="nucleotide sequence ID" value="XM_060509307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9R2"/>
    <dbReference type="GeneID" id="85393206"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="125"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="840" mass="93852" checksum="A8FA6A886BF2C349" modified="2024-05-29" version="1">MNRVESSAGRGRGRHMSLSPRIPDDLPSRLRQLPKHLIPFLPYLNRPDTSHGLERRISAGKHALRLSTMAFWLRTCASSHGNHCAPPPRPGAARPLWLIDVRAYCLVAVKDDREEENSYVALYHYVALSYVWGQASSATATLANIAALQNPGALDGQDIPSTIREAMELTRLLGERYLWVDRLCIVQDDEDAKPAQLQGMADIYAGAFLTIVAAQGSGADEPLHHGLVDETEEEEAESGQGALPCLKEVSSKEWTQRLREFREEPSRSPRRLVSSEGDKNGSPLYYAYQSDQNQQTDADDGRMAVNEQYLPFTMGYGGSPHYIGCGSPYDSPSPMDIESPNFIPASPSYTEVESPVVNERDSPPSSVNEPPAIPQEDVDAPPDVPDTFSATEVPNISRQQEVDAHRAIMEGHSRDLVNTAWCQRGWTFQELMFSRRQLVFHNDTVNWQCHCASWHENQRNIVTGPCSGVEEDEQHSKDDSIENGNDNSVSAPLSSQFLPGVSPWPDFHRYARLVALYNKRVLRYDHDVHDAFAGVLSAFGQSFPRGFICGLPRIFFDAALLWQPYEPLVRRTSDLPSGLPSWSWMGWQGNLQSESWRSGYRYLRGGNSGGSDHFWRPDSWQTRRTVVWSCSLTVNGERSPVGNETAEFSDDPTSEGWCEKYCERAQKSYFTHPQAGTHQFWFPIPLATMASINGSPTSCQPAYLHGLTRRGFLQISKMFHDHRSSQCVCATLCDSNGRWAGVLRLNAASSDPDEYYGSAVGETCELVEISAGSAENQPGEDNGFDGWGEAECARHRGTHEFVNVLWVEWRDDVAYRKALGRVWETAWAQVASKDVQITLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAE2</accession>
    <name>A0AAD8XAE2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_63941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360037.1">
        <property type="nucleotide sequence ID" value="XM_060509422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAE2"/>
    <dbReference type="GeneID" id="85393321"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117271" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="21347" checksum="5522C16CA2CA6A48" modified="2024-05-29" version="1">MHLSLSIIAALAAASAAFRIPEGATDGTYLAYYDESGNEVHVKDPNPITVAGLASADTQVRAVKRPGHSRVRRSPAPSELFERAATVWCGCGNFLNNIDCDRVVQQIKNDINAAGGQSDVGPGLAWYKISGNVVAFLCGRGPGSGRISEGSFAAGLSTITSACGHYVAGTIENGNLDIGYMNNDPNVWFCERARWSTRHEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAX5</accession>
    <name>A0AAD8XAX5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_724680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357908.1">
        <property type="nucleotide sequence ID" value="XM_060512683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAX5"/>
    <dbReference type="GeneID" id="85396581"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171250" evidence="2">
        <location>
            <begin position="23"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="26597" checksum="F5F9D6FEDBEF58D4" modified="2024-05-29" version="1">MISSKFLCPLGVLLVGASRALAFDRISIPTTVKADTDVEVTIKNDIASGSKSFDAGFTNYNLYLSTTPPGWGTGPVCVLANGTKIDVTSVKVKIPADAIPEGSEFKITAMEWNSDPTKDGPSGFEYSNDFSFSGGTGEWGKTELGGSTLGDMDRIPCTAYACARNCNDKYFDERNTTSQDPSVYKNTYECVAACPGTTFPSWDSIINDNGDGSGSSAGPSGSASATATRSGASATASTSPTGSSTSTPTAAQSSSSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB13</accession>
    <name>A0AAD8XB13_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_81900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359726.1">
        <property type="nucleotide sequence ID" value="XM_060515942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB13"/>
    <dbReference type="GeneID" id="85399840"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="406" mass="45348" checksum="5B90392B0A4D6DFD" modified="2024-05-29" version="1">MIFCRQSYGAEKTSKLRDKRTKNMGYCEDLQDEDYSHRSPDSLGRRVEDCPTRIERGPFETIYVAATSTEATSHQPGQKDLIQKPMKRCAMTALDSACTARRHPRLTTHLGCGLFSDNRTNIDYEQESIVVNESSIRSSSAQMGGHDETASDARPTNTETRSPTNSTFVVEAGSSDNREYLPGLGAEEQTTQDQLPARDDSTNFVHTNEGLAETGSTRETAGTSLPESTVEEQAGTRHDPILPASHGSKLGVKGTPALSNVSNINQLVPEVEFSYGVALQYPVHLRIPWTPRGHLAFKTLSELEIELKTVLEEGWTRTTGKQDFAGLKEFRIESWHFDVRGHGAILEFEVKRGREKQFEHMKRKVDEHIRLAIQMSPELRPSFDIEIHIVTGRDSGIRQAGGRSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBE9</accession>
    <name>A0AAD8XBE9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_193214</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000228">
        <property type="protein sequence ID" value="KAK1706299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357805.1">
        <property type="nucleotide sequence ID" value="XM_060501608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBE9"/>
    <dbReference type="GeneID" id="85385507"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042008520" description="Chitin-binding type-1 domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="37"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="99"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="152"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="206"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="258"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="311"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="364"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="417"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="467"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="521"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1706299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="54845" checksum="100DD544ED344C2D" modified="2024-05-29" version="1">MKATIFCWLLPAFVTSQSVTATTATLSPWQTGEVTPDGTCGGTTGFVCSPVWGACCSKDGKCGRSAAFCGDGCQPAAGNCNAPAPAPAPPPGPGSISPDGSCGGANQYNCTTSPFGDCCSSSGYCGTTLGHCGSGCQDLFGTCGAPTNISSDGQCGSNGKTCLGSTFGDCCSSGGYCGTSSDHCDAGCNTAFGTCSNADSGSISTDGTCGKNGKTCQGSKFGDCCSSGGFCGTSKDHCQAGCQSQFGTCGTEDNVSTDGTCGTNGKTCKGSSFGDCCSSTGFCGKSTAHCDAGCNAAFGTCNEAASGISADGQCGKNGKTCKGSAFGDCCSSGGYCGKSSDHCDAGCNASFGTCSTAAGSISTDGTCGKNGKTCKGSTFGDCCSSGGFCGKSSDHCDAGCNPSFGTCNEGASSISTDGNCGPKNGKTCKGSTFGDCCSSNGYCGKSTDHCRNGCQLSYGLCTGISSDAICGTENGKTCAGSGLGNCCSSGGYCGSTGAHCGQGCQKDSSSGCLTANIPSVDGTCGSSKGGFTCAGGPFDGQCCSPSGFCGTSSSHCGTGCQPGSGRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBF6</accession>
    <name>A0AAD8XBF6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654761</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361554.1">
        <property type="nucleotide sequence ID" value="XM_060510746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBF6"/>
    <dbReference type="GeneID" id="85394645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1719470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="164" mass="17396" checksum="2FFAC196832FBBC7" modified="2024-05-29" version="1">MPPAPAPPSASVLLPLHLRPAPTRKSGGRHVPHVPMNKPLFPNELPTPSGNLTTAPAEARERNLNQVVSRQASAIVGWSCLCSSEFLSLNVGSSPGTTDGDIKSIEAITLAIAGSQDEIGPGCRVHSIEGNVVSWTTWYFIWVANINGVELLIPVSRGNAYTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC35</accession>
    <name>A0AAD8XC35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_760747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360851.1">
        <property type="nucleotide sequence ID" value="XM_060515169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC35"/>
    <dbReference type="GeneID" id="85399067"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="11512" checksum="4ED73140F2057128" modified="2024-05-29" version="1">MQIMFLVNREYKNPTKLPTISVTTVNRISNNSVCSDIKMQLNKLFIAAVLGFATTALAQEGKCTAKGECQENTSGVRLFCSSGSCDGKEGQSCTRNGPGSSNVANCPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC65</accession>
    <name>A0AAD8XC65_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_757201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359243.1">
        <property type="nucleotide sequence ID" value="XM_060514864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC65"/>
    <dbReference type="GeneID" id="85398762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF314">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="314"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="45483" checksum="01E6777D505EBCDF" modified="2024-05-29" version="1">MTSNKLRVIVIGGGIAGLSAAAVLRQKHDVIVYDRDDPTSSSSSSASASARERGAGIGLGPNGTKMLKKAFQFSPENVKATICAGSRTYDKQGNLLREMTGVSEPFGSEWLLMHRGDLRDELLRLATGDAAKLGISGPPARVLEGVQVIGVDVEEGKVKLKDGEEVTADVIVGADGIHSLVRQPVIGGPSHMVSPGASLYRFTFPLEKARDILEGYPAAMDPSNSNFLNMMTADDETHRNIIFYPCRDRTLLNVVARIPDAMLSVESIASWNAEGSAEEMLDHFFDFAPWMLEIMKNAQNIHLYKVKDADPLPTYTRGRAVLVGDAAHPMTPFQGQGATQAIEDAEGLRLLLHEGVSADNPENITSALRTWDSVRRPRASQVQQNSRYVTDMSAQAQLDRMRLNWTYNGIHAALRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD08</accession>
    <name>A0AAD8XD08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase/carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_630966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361796.1">
        <property type="nucleotide sequence ID" value="XM_060508871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD08"/>
    <dbReference type="GeneID" id="85392770"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF63">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="250" mass="27922" checksum="5A1C0EE08D21016A" modified="2024-05-29" version="1">MLSPLIYHQPSTTHTHTVVFLHGRGDNAKNFMESLNYSRDSQNRTLADAFPSFRWVFPQAKIGKAVALGDKVSQWFDIWNVNNFVDHEEHQAEGLRESVAAIREILATEAELLRGRWDRIILAEISQGAATGVHTLLNLRLPPGQSRLGAFVGFSCRMPFPGRNLTDTRAVLGLGDVPEGFALLEHTPILLEHCVDDPLVLVANGRILRDTLGKFGAQVEWKEYQEGGHWFNSPSGTDDVVQFLNSHLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD09</accession>
    <name>A0AAD8XD09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein lepa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_59539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360233.1">
        <property type="nucleotide sequence ID" value="XM_060506788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD09"/>
    <dbReference type="GeneID" id="85390687"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16260">
        <property type="entry name" value="EF4_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01890">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000078">
        <property type="entry name" value="Elongation factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="91"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="100"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="165"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="219"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1715090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="690" mass="76868" checksum="974260F25D4E41F9" modified="2024-05-29" version="1">MRGPSATSVRFTQDQLVGIPRQLPRFPLSSKTARISLQGNVPAQRSWQWKTLKRSGIDHKRSFHCGTPTFAKPAAPSRSSLEERILSIPIERYRNFCIVAHIDHGKSTLSDRLLEITGTISASDANKQILDKLDVERERGITVKAQTCTMIYNYKGDDYLLHLVDTPGHVDFRAEVTRSYASCGGALLLVDASQGIQAQTVSNFHLAFAQDLALIPVVNKIDMPSADVPRVLEQMHTSFELEPSTAVLVSAKTGKHVANILPAVVEKIPHPVGDVSKPLRILLVDSWYDNFRGVILLVRIFDGQVKAGDNLISFATGHKYTVGEVGIQYPNAVPQSVLRAGQVGYIYFNPGMKRIQDAKLGDTFTTVGSEDIVQAYPGFEEPKPMVFVAAFPTDQGDYTRLADSISQLVLNDRSVTLQKDYSEALGAGWRLGFLGSLHCSVFQDRLKQEHGASIIITDPTVPTKVEWADGTETIYQNPADFPSQDEHRMRGATVLEPFVTATMTLPEEYLGRVIELCESVRGEQKSFEFFHATQVILKYDIPAAQLVDDLFGKLKGATKGYATLDYEDSGWRASQLTKLQLLVNKQPVDAICRVIHTSQAERLGRQWVTKFKNHVDRQMFEVVIQAVAGRKIVARETIKPFRKDVLAKLHASDITRRKKLLEKQKAGRKRLRAVGNVVIDQSAFQSFLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD42</accession>
    <name>A0AAD8XD42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_784957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361886.1">
        <property type="nucleotide sequence ID" value="XM_060515621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD42"/>
    <dbReference type="GeneID" id="85399519"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF172">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="62009" checksum="7EE4B32CDD4D45EF" modified="2024-05-29" version="1">MADWTSRGENRLPLATKYLYLGVKNRGLQALLSLLFYFIVYPVVEYFRDPKRLRRFPAFKSLAGVTNLVFMREAALGFRSKTLYEKHKKHPVLRTGPNSLSYGTVDAIKDIYGHGTKCLKGEFYETLAGTHFHLADVVDKADHARKRKVLSAAYALKNLENWEHKVADKTERFIVGCDKACTQPLKEGLRPDPADLAFDYRAWTNYFTLDAIADIGLSEKLGFLDQGHDLVRAERMDGSIHEVNYRACLHSTAVAQSITVWAGDWYKFNHRLTSLLSPTFRRWWNLNKGWDGIVYHRATQRLKRYQVGEKLEDFFQALMEDKNGTPNGLDWGEIVAEVSIMMNAGSDTTAIAMNNVMYWLLKNPRCMEKLREEIDAVLEPEEMVAPYDKVKHLPYLRACLDESLRIVPPTTFGLPRRTPPEGAYVLGDFIPGGTTISISAYIVHRDPNIFPEPESYIPERWLGDKGKELQPYFVSFSAGARGCIGRNISYLEQTVLLASVLHRYNFALPFPEWEPERREAMNLMPSPMPLKVWRRNLKQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDA8</accession>
    <name>A0AAD8XDA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_655608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360518.1">
        <property type="nucleotide sequence ID" value="XM_060510810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDA8"/>
    <dbReference type="GeneID" id="85394709"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="129" mass="14402" checksum="58F5128A4B762D06" modified="2024-05-29" version="1">MPKDLILCATFSSVGPLFWCLNSQLNNGAGAALKISSTTFRGLLVQPQIVPGPLWCHFTKHNETSTRNHSRSSARSSAALILQFVSRALHSCLVSGQDWCLLIGARFNEVQELQWYRQCRQSASRVLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE47</accession>
    <name>A0AAD8XE47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_354305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364479.1">
        <property type="nucleotide sequence ID" value="XM_060502540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE47"/>
    <dbReference type="GeneID" id="85386439"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="395" mass="42714" checksum="195CB49E907E79A3" modified="2024-05-29" version="1">MRRVPRLRQPSLLAASPIQCTCAAPATFPISATASRALSTTPATPSRVRKFLWKGGDAPGPEDPYAAESSQALRQQRIAQELAEAEADNQETQRAEQKRRQKPQSRLAHQIKNKRVWAPTEKAVEGGDYVPAKTIEGLEEIGGLEGWWEQEGRWGKESEYVGFASAGEVVTDAVVCAARVRQAVVEALAVAGSSAEVQGRLTAAWTRGDGERFSRATALGLKIGEDGSVSLEGDAAAIEGVVAPLLEAQEAGISEGVVEAAEAKALVEAWGEAWKSISLEDVRFKFAVHKRVFQLTGHRVHDAKLAQINTVGDLIATIVKPPKPTKVAEAIAQQGALLDLPNVRVRDKRVTPIDKETEVGRWKVIEAELKKRGLPVTGHKHLAKPVQRAWIQGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEG8</accession>
    <name>A0AAD8XEG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Voltage-dependent anion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_537411</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361808.1">
        <property type="nucleotide sequence ID" value="XM_060503371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEG8"/>
    <dbReference type="GeneID" id="85387270"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000319">
        <property type="term" value="F:sulfite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09299">
        <property type="entry name" value="TDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.150">
        <property type="entry name" value="Voltage-dependent anion channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004695">
        <property type="entry name" value="SLAC1/Mae1/Ssu1/TehA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051629">
        <property type="entry name" value="Sulfite_efflux_TDT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038665">
        <property type="entry name" value="Voltage-dep_anion_channel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31686:SF3">
        <property type="entry name" value="ACID TRANSPORT PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03595">
        <property type="entry name" value="SLAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="41305" checksum="269EBF05BF91785B" modified="2024-05-29" version="1" fragment="single">QPLPQPQPINEPSRPIRTAIRDFSSQWFLIPQGTAIIATVLHQLDYRFPGLTIIAYVLWATSILLLLLMLTLYAARLTLHPKHTLRVLKHDDAELAGLSSISITFTSVTQTASLALAPSSHESPWTATVHVLWWISLALATTTILILPFIFIKVHPPGVAHLSPSTQLAVTAALTAAAAGGTLCTSSAHLPGAQQLPIIVVSYLLIGMGLPLAFALDVLFWARLLGGNNEPPKEKAFQDMILCGPWGQASYALQILGQAVVGGSFASYTGTGALLSADAAAAPVGYASIFAGLVAWGLGTYWWLFALLGVFRAFFEGGWKPSRIPYTLAGWAMVFPWGVYTNAALQLGKIFGSRAFKVWSTCLAVMLVLVWLWNVGLTVKMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XES7</accession>
    <name>A0AAD8XES7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_583865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362123.1">
        <property type="nucleotide sequence ID" value="XM_060505704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XES7"/>
    <dbReference type="GeneID" id="85389603"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000044">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="33"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1721327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="716" mass="80529" checksum="C89D64393A21F1BD" modified="2024-05-29" version="1">MFMAYVPPPTYVNKLITSKGKVAELRLELNSGGKKDKNYASKKIALKKIVANMTMSNNDMVALFPDIIGCMHIQSLEIKKMCFLFLVNYARMRPEIAVQAIPVLEQDMEDHNPLVRALALRTMSYIHVREFVEATVPLVKHMLKDADPYVRKTAAFCVAKLYDHDRRMIEGSDLIDRLNTLLRDDNPTVVASALASLMDIWERSDAIKLTIDYSNASKMVAILPDCSEWGQTYILEALMSYVPQESGEALLLAERISPRLSHSNSAVVLTCIRVVLYLMNYISDQRQIAILCKKLSPPLVTLLAKGPEVQYLALRNALLILQRRPEVLRNDIRVFFCKYNDPIYVKVTKLELIFMLANENNIDEVLTELREYATEIDVHFVRKAVRAIGKLAIKIEPAARQCINLLLELVATKITYIVQEATVVIRNIFRKYPNQYESIIGTLCEHLDSLDEPEAKAAMVWVIGQYADRIENSEALLEDFLYSFAEEPVEVQLALLTATVKLFIQRPTKGQELVPRVLKWATEETDNPDLRDRAYMYWRLLSTDMVAAKQIVMGEKPPITAESERLDPATLEEMCLNVGTLATVYLKPVQTVFRSARPKKLTDSPALQKHLLPTSIENQKSLSMLGMGGQAQDYNMHGQHIANDPAAANGEMAQAVNDADAYFNSIGPQQMAAMRIDQGDVFGETGGYETGYVVNQHAPQQVVQPAQGSNGDLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFF2</accession>
    <name>A0AAD8XFF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_654682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361570.1">
        <property type="nucleotide sequence ID" value="XM_060510737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFF2"/>
    <dbReference type="GeneID" id="85394636"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF1">
        <property type="entry name" value="OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="38808" checksum="B76050D29E972D8E" modified="2024-05-29" version="1">MSTDTQVQRWQTRQDGLDKLFLSTAPLPQPGPGEVLVKISAVSLNYRDTEVAMGLYNHHKTINPAETEPIVPASDMCGSVVSVGDDVSRWKAGDRVVSIFNQTHLKGQIKPVHMKSGLGFPLEGVLQTHRVFSAEGLVRAPKYLSDEEAATLPIAAVTAWMSINQFRPLGQPGGEGEVVVCQGTGGVAISGLQIAKASGATVIITSSSDEKLEKAKALGADYTVNYRTTPNWDDKVNEFTNGEGANLILETGGAKTLRQSFEAIGFGGQIACIGYLSGKVDDVDDRTNVNLLALKKTVTLKGLINGPRERFEEMINFYEDKGIKPVVDRVFEFKEADKAYNYLYSGGHFGKVVVKVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFU9</accession>
    <name>A0AAD8XFU9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_630512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361990.1">
        <property type="nucleotide sequence ID" value="XM_060508836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFU9"/>
    <dbReference type="GeneID" id="85392735"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="71" mass="7541" checksum="2D7A1D090B8C5446" modified="2024-05-29" version="1">MPSPIPRLLPPIFSIFDSGLAETANLPLFYLSHDAEPSEADNAIGINIHAGPFSTAPIIAHLTHRLVSLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFW9</accession>
    <name>A0AAD8XFW9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_439320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362065.1">
        <property type="nucleotide sequence ID" value="XM_060503094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFW9"/>
    <dbReference type="GeneID" id="85386993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000004">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000037">
        <property type="entry name" value="NIPSNAP family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="3">
        <location>
            <begin position="147"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="3">
        <location>
            <begin position="253"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1721269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="39912" checksum="FDBD4406B7477E41" modified="2024-05-29" version="1">MLSQRLVRAAGAVTPRSALRAFSSTSQQLKVPSMADVSAAPKSVASFNDKSKQFREQLVEQQKQREASAFTQSSSPASSSEPAQDSSVSATSGQKAEATQEPSRKAGPLTNLIYGTKEGRELDAQLEASFSQVLARGKYVHSIVQHEVKPDKVEEYTKLVGSWYPRMASMPENKVHLVGSWRTEVGDCDTFVHIWEYQRYQGYHESIHNIGSHPEFAEFDKKLKSLITSKKTSLMQEFSFWPTTPPRQLGGIFELRSYTLHPGNLLEWETHWRRGLKARREVMEGVGAWFVQIGDLNTVHHLWQFANLEERKIRREKSWSVEGWSETVHKTVPLIQSMKSRILIPMPWSPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG89</accession>
    <name>A0AAD8XG89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UNC-like C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_431656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362410.1">
        <property type="nucleotide sequence ID" value="XM_060503053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG89"/>
    <dbReference type="GeneID" id="85386952"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000082">
        <property type="entry name" value="Sad1/UNC domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045120">
        <property type="entry name" value="Suco/Slp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953">
        <property type="entry name" value="MEMBRANE PROTEIN CH1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953:SF0">
        <property type="entry name" value="SUN DOMAIN-CONTAINING OSSIFICATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069257" evidence="6">
        <location>
            <begin position="30"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="7">
        <location>
            <begin position="229"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="70"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="473"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="894"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="898"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="920" mass="100906" checksum="F9BE6D227A11D994" modified="2024-05-29" version="1">MWFHGQEPSARAFLIVASLLALVCTSTSSQASSSTDTSLTNTQIAFCQFKTINYITHTLPQQCLKTSWPGGRAFSDGPTPMNDNASLPPDDSTKTTHSAGDTVVAATHVSTPDRTSTDNTNSSPTETATDDEVTPRPFMSFEEWKEMMLRKAGQDPSELKSRKTVERATEHDRATRSSGLDSLGIDDGEIDLNFDVVSEKISNIASAPQAIPTELATSDQQQEPVLYDDGRTQYYRSKDAGKTCKERFSYSSFDAGATVLKTNKGAKNAKAILVENKDSYMLLECSAGNKFVIVELSDDILVDTVVLANFEFFSSMVRHFRVSVSDRYPVKVDKWKDLGTFEAKNSRDIQPFLVQNPLIWAKYVRIEFLTHYGNEFYCPVSLLRVHGTRMLESWKDQETQADEEEVVEEPVGELPSSAMNAEIGENTTFASPEGGSPEGGSPEVASDTSPDLLMPRHIFSRLELDNSTCPPLVPLPHSESIPSDPELQIGDRVKPGYQPSTHDRLRAGDSAKRTPEDRSAFIPANLTDQVDETSSSSAKSVPVGAHQSSTYTDPRPGGGESTTIGTSSTKTAQATVQSRNKHNSTAVPSSPTVQESFFKAVSKRLQYLESNVSLSLKYIEDQSRYLQEIQKMAERRQLSRIDIFLDSLNNTVLSELRTVRQQYDQIWQSTVIALESQREQSQRETVALSSRLNILADEVVFQKRMAIVQAILLLSCLILVIFSRAMTQPILAGSFDLGRTSNLDHSDPGIRSEQVAQNTYTSAYDSFGRPFDGEGRGERASLEGASEALQNLPGTPARLLTPASEDGYSCQALESNLCGPDRSTMSQTRPFDTFAENDSTENCHGSSMDFGGHRLVDEAAGTLDNAAQHGCGILPQNSLRSTRVLLDPLPLESKDEAQSANQSLGIVSSTVRKPLPALPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI86</accession>
    <name>A0AAD8XI86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_213519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367421.1">
        <property type="nucleotide sequence ID" value="XM_060501724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI86"/>
    <dbReference type="GeneID" id="85385623"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001167">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="6">
        <location>
            <begin position="563"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="5">
        <location>
            <begin position="962"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1049" mass="117679" checksum="80B9E6430969EF5B" modified="2024-05-29" version="1">MDRPEPGLIKWSQIPGYDSFIHINLQHRVVQLYEPNGLAQRNRFDYTRHSKHDDFPTLTTYDWSPTVPGLLAVGTQTGVVNLLRMDDNSNAYIELNLKMTRTCQAVAFNTEGLLAVGLDRVRMDQCLHIWDVNRLSTMNTTAKGFPKDLHAFSDPAYRLEHSVSVSSVKFFEDNPKTLVVGIKAQGLHIHDLREPGAVVTFQTKCNNNLAIDYADQNYFASSALDQPGIMIWDRRATSRPVASPSYLGAVDEDDLPWGGALRLDRVVEMDDDSSLSESKHSIVRSLRYCRDRRGLLAVLSRSGQLKVLETNKEITHRDMALEGSPELLEVHKSHDMDVQYGDSGRKNDRIVSFDWVTLDSSVLQPRLLVLRANGTFEILEQPSYTSDYLYKLTPWQPPHRGLEEGGPYHEIMEFEPSQSSDMLGPLFVEEALSDIPIFGPNKADVQSIVEKTLQSKFSAADLNSRLTGNDSNSRSPLDISKSTAEKMRALRTELKEKARKADTNGAEISIMEESVSSLAQLSLSTEGPVSCRHMHESLLSLPLKARDLSMEAQCLLDHVMLLRAKEKYLFDCNINRVVVADDPWLRYMWDWISDAEDAAADGGMKLSPLDLSYMGVCTIWCDDLGRKPSSRLPEASPIPETTLWEKCIGSICKKRRLPKYEGIHTKKPFHRQLCLDICEWGDTAAHEARGAATHDPSQDYPTTAHTMAAARALFKGNTQEAIGILKTASVTHPELLFVSLALQLIGKSNHHLNKEQLDFDEAVASKTDPYLRAISSLIATGDWFAIANQKSLPLSDRAYVAVRNFSDEQLTKWLNEQVSMAVGTGDIEGIVLTGITDRLVDIFAKYVEKFNDFQTATLVMSICAPRYIDDYRCLAWRNAYRTYLQRHKAFLQRTKFEVESTKKSKRGGRPTIKPPSRQIALRCVYCDAETTLAGQGGAGSGPPPGAPDSRNPLMATSINAGISCPNCGRHLPRCVVCLEVVGVPRSDRPEHNGEPERCMAANFPTFCLKCEHVLHLDHARQWFTRHVECPVPECRCRCNFRANPELNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK46</accession>
    <name>A0AAD8XK46_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_716640</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368911.1">
        <property type="nucleotide sequence ID" value="XM_060511865.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85395763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000819">
        <property type="entry name" value="ATP dependent RNA helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000500">
        <property type="entry name" value="ATP-dependent RNA helicase DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000002">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="689"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="936"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="232"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1728856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1488" mass="165851" checksum="6ADEE6C489CFE179" modified="2024-05-29" version="1">MAGAKKKKKPAANPARGFATTSVASSKPRTEPAEGTDAAAAARATTAAPDATSKSDAPSSDPQSSSNGAGDKATKAELSPEEFEKQLDESELQLMVEKYAQKTKRDAQRQRTRLETDRRLLRGQADTVNSRKWLPQELMDQVLDLIQAESRFASSSVSTETSVNGKLLPEEDMTIKLWTLQQTLASVGFPEERVQAVMRHILDIAPNIPSFTKDSLWGLEEALDWLARECPSDELPDYEGRGNKSMRQLDSSDTPAESPLPSGATTPVPDGRQKPGQASKNGNRKKAVVTCDIDIEPDELAPVYLETKIKLFELEKSQQGKRKQNSNTSETGDEADLQAELRAKIVRIEKDVLFDKFAAEQEWKTKKVVLEKEFAAAKKQQAQEEKEKEPPKAVAEAAASSDGDINDEAERIAAEILAQNDDDDDGGLGDLFANLPVTEVDATGKSSTVLNDTDGVKITIRDFGKWTGVSPMRALEEACRARDTSTRINYRLISEVPFANRHYLSITWAKPQEVPSASQDDTVDVVNIPSSFSFSMKSIATPDKKQSEAYVATWALFHIFGTSAKEEKVGMRLPHVWRELWDELAEARKSQLDSKDREAIRELRALVRQRQDQELEDGVILPNAFRGRAAARNQNDNKDEAAQEAAKRLSNGPEYYQNIWAQKINTPRYQTMLQSRMQLPMWNFKQQVTDAVDREQVVIICGETGCGKSTQVPAFLLEHQLAQGKPCKIFCTEPRRISAISLARRVSEELGESRNDLGTPRSLVGYSIRLEANTSRETRLVFATTGIVMRMLEGSNDLREVTHLVLDEVHERSIDSDFLLIILKKLMLRRKDLKVVLMSATVDAERFSNYLGGAPVLTVPGRTFPVQVKYLEDAIETTGYTVGQSPQEKMVDLDDDVVEVEAEGPKSTVGADLSAYSAKTRNSLAQMDEYRIDFDLIVQLIAKVASAPEYVPYSKAILIFLPGIAEIRTLNDLLSGDPSFARDWLIYPLHSTIATEDQEAAFLVPPPGVRKIVLATNIAETGITIPDVTCVIDTGKHREMRFDERRQLSRLIDTFISRANAKQRRGRAGRVQEGLCFHMFTKHRHDAVMSDQQTPEMLRLSLQDLAIRVKICKIGGIEETLSEALDPPSAKNIRRAVDALIDVRALTPAEDLTPLGNQLARLPLDVFLGKLILMGAIFKCLDMAITVAAILSSKSPFTAPFGQRAQADLVRKGFRRGDSDLLTVYNAYLAWKRVCQSNTASGGKDFQFCRKNFLSQQTLANIEDLKGQLLVSVADSGFLMLTDEERRALNRVRYGSNSRGGRRNQSFFDIPQRVSINSENDAITTAVITWSFYPKLLVRESPGARGLRNISNNQSISLHPSSVNKGHNELKWLSYYHIMQSKSVYHAHETTVADPFAIALLCGDVRADMFSGVLVLDGNRCRFALPDWKTMLVIKVLRTRLRELLTRSFKQPGKLPSAQHERWLAIWQKIFSQEANKDRDMTASVSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK92</accession>
    <name>A0AAD8XK92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368948.1">
        <property type="nucleotide sequence ID" value="XM_060513656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK92"/>
    <dbReference type="GeneID" id="85397554"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="66" mass="7145" checksum="D5162181D9BD0C1D" modified="2024-05-29" version="1">MQPKAAMPVPQIRPAIRHRGLIVVTAAVTAVAVSFRYTALSRRTNDQNQCSSNPYYVSVDRSGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKE5</accession>
    <name>A0AAD8XKE5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase-like superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_569522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369057.1">
        <property type="nucleotide sequence ID" value="XM_060504207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKE5"/>
    <dbReference type="GeneID" id="85388106"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF5">
        <property type="entry name" value="TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="2">
        <location>
            <begin position="369"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="677" mass="74577" checksum="3A4176CCBFC0FD7B" modified="2024-05-29" version="1">MADVEEPKFNSLAERIAALNQQKNFQAPEAKAKRPPPPPPPTNRPVPRSQTLPVTQTNGLPTPQKSPSIPPRPNKATAPAKPAPPPLPRRTTDSSQVETSTSPAPRDRIAPPPLPTRSSTQQISPALPPRRPSTQQLTVRRNSNASEISTLSSLSLNQTVSSATSVHSIDGPTRKLPPTLDQAKLPPLPPTKREREAAQAKEAAAQQPKFPLVSVKSSPAIRQIEPPQRPVLPPRLTSRSTTQQVHRQTLEEEEPAKPRRLPPPPAAYIKPPPPTTNQDQQANDRPPLPGRRPTPNDDAPPPVPLSSRPSAAQIEAVSARVVERANDCLICRDFSGPDGVAAQYPIHVLPRNDPVGYLAQVLCGPFASLTDKARAIFTWFHHNIAYDCAAFFGNNIRGRSGAETILMGKAVCSGYADTYREIATHAGLECITVVGHGKGYGYTALKKGERPPPKKADGHAWNAVRIDGGEWKLLDACWGAGNVSDVTKEYTKSFKPHEFTRRNDIFGLSHYPSDDRHFFRPDGRVPSWEEYYIGPVHGDKPIVYTHAYEEGVWDHTVEPKELQIPVHSGQVVRFQWSNKCEHWTSEKHGKGKPPLLFLSIKGRDGRKDDMVPIQTDGFWHWADVNAIDLGAPGQSVSIAMITTIDGQDARGMTADYYFSKKGRCGMAWTFLMKWELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKM1</accession>
    <name>A0AAD8XKM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369161.1">
        <property type="nucleotide sequence ID" value="XM_060510147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKM1"/>
    <dbReference type="GeneID" id="85394046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="23124" checksum="7F82D52F856B86E7" modified="2024-05-29" version="1">MLQMSQLPSRAGYSPLVPSPLNPDVHAIAPQRCQKLREKRRQQGRGDVSPTQRLLRHKAAMAWKSEALTRESTMYTRDEILDILAECDRQDEVAARGLVVMATSNQPPWPPSKKQQQKKQPKVHIRAAHWKEHEGEEYDFFCEADDDADESARQWGSLMPRLRSPFSKDTARRVALAFGLMCICGCLPALRAHGFHMYSATEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKZ4</accession>
    <name>A0AAD8XKZ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_50022</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369356.1">
        <property type="nucleotide sequence ID" value="XM_060503294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKZ4"/>
    <dbReference type="GeneID" id="85387193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="30"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="518" mass="57114" checksum="323F30E115AB07CA" modified="2024-05-29" version="1">MGKPVEDLAVIPGDDLPWWKHAHLRKLNFITLSMVLFSSANGYDGSIMGGLLALPRWNAFTHNPSGAYLGWITGIYWLGNGIAFPIAAMCSNRWGRKPGIYVGYLFLILGVVMQTAAQNEATFTYSRLFIGIAASWLGNSAPLLINEIAHPKQRSIANALFMVGWYFGGTLCGWVTFACRNIASDWCWRIPVVLQIVLPFVALPGFLLSPESPRWLISVGRVEEATEILATHHAGGNRNDPLVTYQVVEIQATITAEKEASSSASYMDMIKTPGNRHRLFISVTLGIYAQWAGNGVVSYYLLILNSIGVTSVTNQTLISACLNVWNLLWAIAAATSVDKLGRRFLFLTSASVMLVSFIIITGLSGSFATTQSSAIGSSVIPFLFIFFAGYDIAMTPFLTAYPCEIWQFSLRSRGLTVTWCSTVIAIFINTFVNPIALEAIHWKYYIVFIVMLALLWITVFFAYPETRGHTLEQMAVIFDGDDAAVPPAAAVSEKTEALVTHGDDEDKRQYQSDAEHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL63</accession>
    <name>A0AAD8XL63_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_52799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369442.1">
        <property type="nucleotide sequence ID" value="XM_060503309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL63"/>
    <dbReference type="GeneID" id="85387208"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8439" checksum="C6A49BB4A4CFC012" modified="2024-05-29" version="1">MRPSQHLKVTLPPPLLPSPFGHSVSKNRCASHRLLWLSMLRIPGVIHPPPNPHVSASPAANRLNYEFPSFPPFLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLJ3</accession>
    <name>A0AAD8XLJ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oxidase ustYa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_568131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Mycotoxin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369656.1">
        <property type="nucleotide sequence ID" value="XM_060504031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLJ3"/>
    <dbReference type="GeneID" id="85387930"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF11">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042037984" description="Oxidase ustYa" evidence="4">
        <location>
            <begin position="21"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="24716" checksum="679CA5602ABA193A" modified="2024-05-29" version="1">MLRCCLDIILILCLLGTTTAVLRQDAGRHEITAWPVGSDYNHFVPHGKPQVDVSSRGVPKPSGPDQYEVTAHAFHDQGVLNETLDSWQGLSHAFVRAFPYDGSGPQKLFSGDLFEIAAFHQIHCLTSILEDFGLLAAGVPKEELPGYHSGVTLTWEEHKAHCFNYVRQALMCFADSTAEGHIDGDTHRVADHGVMHVCNDFDALLAWSKEPERALPKSWRVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLX6</accession>
    <name>A0AAD8XLX6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Maltose permease MAL31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_604834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369793.1">
        <property type="nucleotide sequence ID" value="XM_060507298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLX6"/>
    <dbReference type="GeneID" id="85391197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="58646" checksum="F1940F586A23EEC0" modified="2024-05-29" version="1">MANYDDGYPAEKVDSQHDAKHLEVSADSQLALAADFEDHEMGIWKSFARYPWACAWCVYACWTIILLSFDVQAAGAVVGIPEFRKDFGYEFNGDYVLPAIWQSAFSGAPIATAVISSIASAELADYIGRKKVLALALIISFVAVAIEFIATTNPVFFAGKLLNGFMVGAVGTIMVSYIGEITPLALRGIFTCGVGVAYGIGPLVAFIVINYTGTVESRWAYRTVFCCQFGFAGVSAILWPFMPESPWWLVSKGKKDEALKSLGRLGHSGNEGRAKLALIERTLDEAKAETDGVTYLECFKKSNLRRTIISIMPLCIQSFSGIAFVASYFTYYLQLAGYSTSMSYQLQIAQPVLSIVGNLMAAAVIDKVGRRNLTFYGLAILTVFLLITGGLGTGTSQPMIKGTVAFILIYSWWYNVSIGSTAFSLLAEVSTSRLRAKTVAIGYASQNSINVMWQFVIPYMFNPDKANLGAKIAFIFGGLCLFSLAYLWLFQPETGGRSYEELDEMFAKGVPARKFKSYKTTVQLRNETAAQDENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM89</accession>
    <name>A0AAD8XM89_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Multifunctional methyltransferase subunit trm112</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eRF1 methyltransferase subunit trm112</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_603944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369967.1">
        <property type="nucleotide sequence ID" value="XM_060507254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM89"/>
    <dbReference type="GeneID" id="85391153"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000021">
        <property type="entry name" value="Multifunctional methyltransferase subunit trm112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041975895" description="Multifunctional methyltransferase subunit trm112" evidence="8">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00083044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="14078" checksum="960B725C340222DD" modified="2024-05-29" version="1">MKLLSLNFLTCAVKACKSSAASFPLHPKDAELAQDDIEVNPQLLFNVLPRLDWAALRTNATELGFPELPTEPPSAEQLEGDEKMLKELHHLLMETQIMEGKLVCGNCGHEYAIREGIANFLLPSHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMK2</accession>
    <name>A0AAD8XMK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cohesin loading factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_601953</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCC4/mau-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370275.1">
        <property type="nucleotide sequence ID" value="XM_060507138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMK2"/>
    <dbReference type="GeneID" id="85391037"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019440">
        <property type="entry name" value="MAU2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21394">
        <property type="entry name" value="MAU2 CHROMATID COHESION FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10345">
        <property type="entry name" value="Cohesin_load"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="937" mass="103646" checksum="061AE6D0FF4F6011" modified="2024-05-29" version="1">MTYRGSLPSGQAFNGQQHVPQPYHDPYGNSNGNGGGSGNGQNQNYANAAYGTHGQAQPIHGSYHQPPTQAPAPILPAPTPMNMQANGYGQFPAYGGTFPHHQQQQQQQQQQQQQQQQPPQYPHHHQLQQPFPHGNTMNVQFAPPHSPFVQTTHASRSPALAPAPTPTPTPPIYAEYQPTQQPQHQPQFQPHFQQQPQPPPQTPQQLQQLQQQRSPQVFPAVPQYAQFSQPPMGQTQAVPVLNQAFAEPSPVQRSPEPHFANSPTVQPARSPSIARKSPAISSINSPAISSRGSPALSTKARSYDTTTILVHVAEECFEKARRGVQRVAVSGSDEQVREYQKLITTGLACLEAAFQSNRLSPRQEAKARLRYASILCDETENLQEAETALSKGITICDKHRYADLKYCMQYLLLKVLFQRNQKAAFIAVDKNIADCLTFKHIHWVYAFRLLKATFHVHAGSPPDAAVLDNLRAIAVLASERGDNAMLVFASLLEGLSVLRNMRPDTIERVQTCLAQATKFQLDPSVQIPQLDVLTLLLDLACSMHQKTPDILIHKLRTLQAKLDANLGSQTWTDLNPEILIPVKKHNSTSATLSDDTSSILRSGPTDGQHDYIVMTFLNRLEIIVLTYTFSGLAGMYRPGSDPKRSHEFWKEGFDVLAKWNKEIAPSVPAASLRESMEQSKWRTEIFCYLQALTGLYFATHSQWPKVEQCVAQLQQAITPAVNEIFSVFSLYLSGVYHQGTGDLETALLLFEDERLSVDVGRGGPGGRKPAKLELCILAALNRIWILQDSSYRDEMTSTELLDQLRPMCTEHQDPDIRTAFNLVQATAQTMPPPSMHQIKTSITNSLNGSRVTGNTHCLAIALSIMRSRLFDNVVGEQALKSARAASTQAKRSGNLLWMSVADGMLADSFEVQALFADAEAARQTATDYASHAFTGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN21</accession>
    <name>A0AAD8XN21_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_404088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370450.1">
        <property type="nucleotide sequence ID" value="XM_060502859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN21"/>
    <dbReference type="GeneID" id="85386758"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="28195" checksum="DA8324DF58B53600" modified="2024-05-29" version="1">MPTLLAPHFPHYVQMEPSKRPRRPPCRHQANQLAFRTAHKPTFPLPLRSGHLRGGACKSPNLRPRSLLLRLRSGRLQRNSGFCVTHHKEPRERSSQLESELSSRDKRHWPPSCSSLQMLLLLMQTAPASLPSNLRVLRGSWPMPRRAPLCASSLVGNVTPLTEECMETKPTRRTHVGPKHALDGSRRRRRRHCWDCKRTSPPATSTGPPNLRYSIYQCVDRLENPSSSLQGPIPRRTAAHRTPSVQPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNF8</accession>
    <name>A0AAD8XNF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_377916</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370688.1">
        <property type="nucleotide sequence ID" value="XM_060502691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNF8"/>
    <dbReference type="GeneID" id="85386590"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000100">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="119"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="617"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="644" mass="71153" checksum="DB75AC64620BD29A" modified="2024-05-29" version="1">MADDKHLDGAAVSGDFSNMEKARRGSQATVDLNDNVDAKIRNPLLGITRAELLRDVEAFAHDKGLQEYIPVLKKGALVAQDPTGYEEIDGPEALDATEIQVLRDEIEHKWRIPKILYLTIITCSIGAAVQGWDQTGSNGANLSFPTVFGIGGTSHHDTLLVGLVNAAPYIGSALIGCWLSDPLNNFFGRRGAIFFAANFCLWPVIGSAFSQTWPQLLGCRILLGIGMGAKASTVPIFAAENSPAPIRGALVMTWQLWTAFGIAAGTAANLAVAKTGAIAWRLQLGSAFIPALPLVLLIYICPESPRWYIKKNRFPDAMKSLLRLRNHPIQAARDIYYIHTQLQVEAEIVGRSNYAKRFVELFTIPRIRRATLASFTVMIAQQMCGINIIAFYSSTIFKEAGTSEYNALLASFGFGMVNFLFAWPAIWTIDTFGRRSLLLFTFPQMAWTLLAAGLCTLIPGTGGAHLGLVALFVYLFAAFYSPGEGPVPFTYSAEVFPLSHREVGMSWAVATCLFWAAVLSISFPIMLADLGVVGSFSFYAGLNVVALVMIFFWLPETKQRTLEELDYVFAVPTRVFMRYQLTKALPYWFKRWVLFQRDATLEPLYKFDLTHEDHHGSETYEKTQVEQRDQKRSGSATGVDVTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNN8</accession>
    <name>A0AAD8XNN8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytosine deaminase</fullName>
            <ecNumber evidence="14">3.5.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Cytosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_747051</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>cytosine + H2O + H(+) = uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from cytosine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.1" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370780.1">
        <property type="nucleotide sequence ID" value="XM_060513369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNN8"/>
    <dbReference type="GeneID" id="85397267"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046087">
        <property type="term" value="P:cytidine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019858">
        <property type="term" value="P:cytosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000016">
        <property type="entry name" value="Cytosine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF190">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="17">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00060700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00066550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00074321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00084039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1730725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="149" mass="15833" checksum="271DA97460D45952" modified="2024-05-29" version="1">MNDAEGLAIAIEEAKTGASEGGVPIGAALISADGKLLGRGHNRRVQMGSAIHHGETDALFNSGRLPGKAYKGSTMYTTLSPCDMCTGACLLYGISRVVIGENKTFLGGEEYLKQRGVEVVVVDNAECKALMDKFIAEKPEVWNEDIGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ04</accession>
    <name>A0AAD8XQ04_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_245073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060501893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ04"/>
    <dbReference type="GeneID" id="85385792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032922">
        <property type="entry name" value="SON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46528:SF1">
        <property type="entry name" value="PROTEIN SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="687"/>
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        </location>
    </feature>
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        <location>
            <begin position="717"/>
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        </location>
    </feature>
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        <location>
            <begin position="750"/>
            <end position="788"/>
        </location>
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        <location>
            <begin position="789"/>
            <end position="804"/>
        </location>
    </feature>
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        <location>
            <begin position="843"/>
            <end position="856"/>
        </location>
    </feature>
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        <location>
            <begin position="857"/>
            <end position="867"/>
        </location>
    </feature>
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        <location>
            <begin position="871"/>
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        </location>
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        <location>
            <begin position="904"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="105564" checksum="39D1F80927FC6370" modified="2024-05-29" version="1">MAVHLTPAQVELINSLAPDDIPIKLRCASCSKPAVNAFRLPCCEQAICETCQSSLPSSCPVCEHSPVSADDCTPLKSLRTTIKVFIRTQEKKRDEARSKSAKDSAPPTPIDAKPNAQIAGPDETPAADTPSQPAAIPDEREESAVAQPAPIEDANTADVADADATAAQDQNDAPNHDEEPIISKGEDDDDETVIITGDETAADGSKLARPQEEDVAENDGAEGDDANANGNANFNGMNGGNFQNMNFTGNGDFNQMQMMMAMQNGMGSNSFGNFPMMGMPGMGMDPMAMQNMYMNGGYGAQGMGMGGFNGGFGSGSNNWNGQQSWNFGQDNFNSANAAGMGSGDYGNYNSGFQSGYNQGNYGHQFNDYRRNNYGNRGRGRGRGFYNGGYGRGGYQQYGGYGDQSHAQQQYGNNMYGQGSEDGTRAAGNVDEFGRERPNDQDATSNAGGGDNAENGDGSRPADDGGDEQGQADQENAMNTDMAQASGDYSTYNGNGMSGGYGPQGFAPAAPDVPINAPTGPKAMRQGLPNTSLHTLRARGYVVPDERGRQSSVDALAIQSPVVDQQQQQQQQRSRSSSSTRTKDKDRSRRRDASRDREREPDVRSERDHGVRERDYSRSPSRSRDQSRERKSERGGGDRDRDRDRGDRHRRRRRRSESRSVVDDRDDEYRRRKHKSRKHTSYNDEDDVKSRSRDDGHEERSRSASPSDSKRSSHRSRRDRDEKRRDREKDNKHRDDNYDDYHRKSSHRSHRERDRDRDRGDRDRDRERERDRDYDRDRDRKDRDREKDRKRDKHRDREHRHRSSRKQSAEPPTPVDRDFNPPTGPRSGGGSGLEIKGVGSKSGRSSDRQDGGERRDSQASVNSKSAPSVPTKDAHALEREARNRERLLKETQRMAGLAGLAGAKRSRDESSGGGDDGKRSRRKGRRSEAISIDEEEERMRRMEAEREGSRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ06</accession>
    <name>A0AAD8XQ06_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_646285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371377.1">
        <property type="nucleotide sequence ID" value="XM_060509947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ06"/>
    <dbReference type="GeneID" id="85393846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="31185" checksum="9B3CE5897ACAB581" modified="2024-05-29" version="1">MTAPTNTTTATSSPATSNPQYQNQQVYESGLEVAEPNAWNRTNNDIHLPEVSPYNHSEAKTTTFPEVADDPLSWHHYHKQNPNLEVSSSPSVASAAPYYYAGAAGQQHPPGYHKPPPGSPGYGSGSLDGDGSGKGKKATVCGMRRKVCYVVMGVAIVLVVAAIAVGLGVGLATKKSGNKSSSGNSTTTPATSTANATITCPAADNVTYSSPDAPKRTFRMICGHDFNSADGATDLTSENATTMAACIDLCASKGDDCVGAGWGDYYGNHVCWMKSKLGTMNVSGNWYFAVDVNKTSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ87</accession>
    <name>A0AAD8XQ87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Family 2 glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_1435</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371760.1">
        <property type="nucleotide sequence ID" value="XM_060501286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ87"/>
    <dbReference type="GeneID" id="85385185"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06434">
        <property type="entry name" value="GT2_HAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="57969" checksum="DC5957BC02B0F7D0" modified="2024-05-29" version="1">MADIMNLFLPNLGFGWSPTAWMYLFIALWLHRYTRLLVNCVSHWVYKSKPIPANPTFTADDVTVIIPTIHNVFEELRPSLLSIIACNPRVLMLVTTSEKHASLEKLARSLPHPNVQVYSTPIANKRLQVCEALPKVTTKLTIMADDDVTWPSTMMPWILAPFEDPKIGGVGTCQRVKRVWDGPLSTRIFNWLGAAYIERRNFEISATHNLDGGTSCMSGRTGAYRSEILSSHDFLEGFKTEKWGKYILNADDDNFVTRWLVSHQWKTWIQYEKECELETTLENSTKFLYQCSRWARSNWRSNWTSLVRERYVLTQQPWCTYALHIATFTSLAFLFDPLIIFALWKGTADWDVESRRQALWAQIIFVFGFTKVVKLVNLFRRNPSDILFLPVSILFGWAHGIIKLYALSTLKMTSWGSRADGDTNDDIRLTPRPKRAMSLTTPPGGQDLVRYRFERQMTEKVSDWHRPANEARRPQTVRMNTFPAKDIKAPHVTFSLLEHPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR01</accession>
    <name>A0AAD8XR01_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cellulase</fullName>
            <ecNumber evidence="3 9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_564153</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 45 (cellulase K) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3 9"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371893.1">
        <property type="nucleotide sequence ID" value="XM_060503612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR01"/>
    <dbReference type="GeneID" id="85387511"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052288">
        <property type="entry name" value="GH45_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000334">
        <property type="entry name" value="Glyco_hydro_45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39730:SF1">
        <property type="entry name" value="ENDOGLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02015">
        <property type="entry name" value="Glyco_hydro_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01140">
        <property type="entry name" value="GLYCOSYL_HYDROL_F45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922292" description="Cellulase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolases family 45 active site" evidence="11">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="24687" checksum="FA33CA72F0091142" modified="2024-05-29" version="1">MHLTSPLTLLLLPILLSRQTNAQSTSTGSTTRYWDCCKPSCAWPGKIPSSSLAAGPVTTCDRNDNPLSDGGATRSGCDSGGGAYMCSSQSPWAVSDDLAYGFAAVRISGGTEAQWCCACYELTFTSGAVAGKKMVVQATNTGGDLGQNHFDIAIPGGGVGQFNACTDQYGAPANGWGQRYGGVSARAECDGFPAKLKAGCYWRFDWFKGADNPSVSFRQVTCPAEITNKSGCRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZR9</accession>
    <name>A0AAD9CZR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isochorismatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_569383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369035.1">
        <property type="nucleotide sequence ID" value="XM_060504187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZR9"/>
    <dbReference type="GeneID" id="85388086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01014">
        <property type="entry name" value="nicotinamidase_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF15">
        <property type="entry name" value="BLR5631 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="24"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="20416" checksum="069812939BB05034" modified="2024-05-29" version="1">MASAAVSMRSMLGVPASTTSTSDSILVIIDAQNEYATGKLAVSDVEASRAKIASLLEKYRVAKAPVIHVVHEVPAGAPLFTPGTELAEEFSELKPLEEESVVTKNFPGSFTGTNLEDLLKATGRNKVVLTGYMAHVCISTTARQASEKGWDVIVVEDAVGDRDIPGANAQELTKVALAEIADAFGTVVKSQDIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0F5</accession>
    <name>A0AAD9D0F5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_568768</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369395.1">
        <property type="nucleotide sequence ID" value="XM_060504118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0F5"/>
    <dbReference type="GeneID" id="85388017"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000270">
        <property type="entry name" value="RNA methylase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="28338" checksum="AE212B59DD0A5CAC" modified="2024-05-29" version="1">MKAATRLPLTDECHHYKSKAEVPWDLQKYFSQRYSLFSWYDEGVYLTDSAWFGVTPEPVANQVANEMYHTDASKHVLVDIFGGAGGNTIAFALSARWDRVISIERDAATLACAQHNAELYEVAEYITWIHGDCFDYLRKLRESPEELSEELRVDMAETVVFASPPWGGPGYRTAEVFDLSKMEPYNLEQLHEACKPMDHALYLPRTSDLRQVAKLAPEGEKLEVVQYCMEGASKAMVAFIPGALSTKQSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0G9</accession>
    <name>A0AAD9D0G9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">40S ribosomal protein S29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747974</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370023.1">
        <property type="nucleotide sequence ID" value="XM_060513540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0G9"/>
    <dbReference type="GeneID" id="85397438"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="56" mass="6666" checksum="58932FD598D959AA" modified="2024-05-29" version="1">MSHESVWNSRPRNYGKGSRSCRVCKHTAGLIRKYDLNLCRQCFREKAKDIGFNKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0K9</accession>
    <name>A0AAD9D0K9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369709.1">
        <property type="nucleotide sequence ID" value="XM_060515152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0K9"/>
    <dbReference type="GeneID" id="85399050"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="24796" checksum="75935C168CACC802" modified="2024-05-29" version="1">MSSLTNSRTSTVGTEYGKTIRMGKAKVVGLSPLAVCRIRTNLLMEAAPAPCAPFAPEPAGALIRLMTELEKARSGFLPQQGPGTGRLHRGRDSEQNPNRNRSATCRRAASKAYHTTVTTPHLSHELGGVLGKANTSDALQAVVLHNAWLLGQPILRGQVLWSLVLKIDAVDLESSKLSFRSRDGLDLDWPALTGLELQMIPAWQSQIQLEFPVYDCIGDSPDLTKMSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1M8</accession>
    <name>A0AAD9D1M8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_647434</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369921.1">
        <property type="nucleotide sequence ID" value="XM_060510070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1M8"/>
    <dbReference type="GeneID" id="85393969"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07866">
        <property type="entry name" value="STKc_BUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000562">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="35"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="385"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="522"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="552" mass="62920" checksum="BD0F56E5C36FAA9A" modified="2024-05-29" version="1">MDSSAPNGGLSPRTFAMQHQRPRASFQGCSRISDYELLGKLGEGTFGEVHHARSRKTNAHVAVKKIIMHHEKDGFPITALREIKLLKLLSHKNVLQLVDMAVEHPQRASKSLMLNYPIRQQQFLTRIVTGDKRKRPIMYMATPYMDHDLSGLLDNPSVHFTEPQIKCYMQQLLEGLRYLHDQHILHRDMKAANLLINNKGILQIADFGLARHYEGPTPKPGHGAGEGKREYTGLVVTRWYRPPELLLHLKRYTTAIDVWGVGCVFGEMLVGKPILAGESDTHQLDIIWDLMGSPTPENMPLFNTLPGAEAVTPRPRPGSITNKFREYGTGAVSLLKELLRLDWRSRINAADALNHPYFKMAPMPADPGDLPTFEDSHELDRRKFHDRQAKLPPAPKGGTVGMGPEAHGANAGFNNSDAYSNRNGVNGRNANVPGGHRNGGDERRPAWQRDNRGLPPRPPPPEYANGGPMPPRDDYRDRDRDRRPRSRGGRGPDVDTYIPSYRDDVPPRHRDDRPPRDRRRNSRDERWHERDWDRRTRSRSRSPMRERDAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D219</accession>
    <name>A0AAD9D219_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Eukaryotic mitochondrial regulator protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_747817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370251.1">
        <property type="nucleotide sequence ID" value="XM_060513509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D219"/>
    <dbReference type="GeneID" id="85397407"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="320" mass="36758" checksum="CC2F7E227E0EF7FB" modified="2024-05-29" version="1">MSARAGSSLSPLVLGTKWCDASARTTASRCAFSTTPVQSRRSKLQHRMHDFFKNGRGAGLKESEHGVNYLGGSRDQPFPMNPFFRSEPVLSERLRHEVYRRVTVAKESLKLVSAELGIDVRRVAAVVRMMEIEKQWVKERKPLATPYAKAIMSMLPQTYLEEGGRNQRAHEPVNEIHVHKLTMQQLFVPVSESRQFNREDAAKAFHRNMLSIDDRSPHKELIDMRRAAANGGDRAELTRKFRAETRAQEDRLVERERKRLEKAEEETTRVDTGRFEFRFKEMNVETVGKNGRSRGGVGWRYGVPFYDRRKGETKIPTSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Q9</accession>
    <name>A0AAD9D2Q9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Helicase sen1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_564586</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371658.1">
        <property type="nucleotide sequence ID" value="XM_060503657.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387556"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001152">
        <property type="entry name" value="tRNA-splicing endonuclease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024481">
        <property type="entry name" value="Helicase_Sen1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12726">
        <property type="entry name" value="SEN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase Sen1 N-terminal" evidence="10">
        <location>
            <begin position="89"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase SEN1 beta-barrel" evidence="13">
        <location>
            <begin position="1187"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="11">
        <location>
            <begin position="1337"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="12">
        <location>
            <begin position="1632"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="921"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1039"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1899"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1470"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="931"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1055"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1922"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2007"/>
            <end position="2020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1731603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2071" mass="231422" checksum="9B83DFB88FF82960" modified="2024-05-29" version="1">MESQPVEDILEQSYRKFTQIPPDFHLLCPKVDEDDFEDYDDLNTDGEEITALEKQERVEKWKERLDIAYWTSLLLAYGKDKAGVWLDAWGSRMAINLHNCDKCVLNWHMYRKKYLQVFSEKWPEEAVAGIENCLHRFDFDRIDKGLQWAKDIILKVENEGRAFARSDLGEEQGAVLLTVYEALCCMAYVSVPEKRTLFQFVFVRLSGKKPLKLGENVLLPAMTQFLFGEDKVRLQFAEKSWERLRPKSLTQEQFNWAIHDNLVVAIQSVSALNPRDPASLPEIERFWKAVNWIIKTLDEKLLLHGIRGMEIKPSIYDLLFVHMQCESEAILLLIIQALTVLLETSPQAFWDTIGDARPFVVIEQLLSQPLFKQLLAQSLTFAIKYDDGTGKNDSVESITTSWINTWIASLKRQQKGDACEQLLHLLFEQVIHDARIGEQGKAACIRAGLDALDHVLRSFLDPTIDVISGTTSVYINTILNVTLKYKDIINDGADTRSTDQHTLGVPKAAMSVISAALSLDSRVTAEEHLELRKATPKPIQTAVTRKSADLWDGFLENLYEGKLVLAKTMLMAMAPLINVERFHPNRKEPEKLDPAKKSFNNRFHMVAEALGRVLQRMCEFTSPQLNELCLMAQSIRPIIAFTVHGEDEISSASAELIKLITEQPSKEDALTVLLERNLSTTLSSMIFAIRRIMEPAHAAWGPARNIINTAKVVLSGLSDLSSGILRSKTLDSNEQIAVTGWWVAHWRYIEVAFTSTGNWSHLADIKVMQDFCRDVIELADGMLAQDGLFASALQATTSQTDAKQAKPKEEELTKMQQLLKDPQRHLFGIVRMLRLRDTYLVEVTVKVVAKLLTRLRENSIDIPSDSKNYVQDSCIKLSTTGRYPVTTNMNDQQRAELLKALGEDDDIEIIQIQPVSKEKPKKQSFLDAWSKSGSSTPTSQAVRSNKDDVLELSSSVDKKRSILDQMAARQKASPAIPRMAVKPKLEPVVTQASKNALIESRKKAKLEKAKRDADEVARVRALRGAANVGEGSGLKGLSGVVGKEHTTQKSQILVDSDEEDNDDSGDEDLNNLINKGQQGQMAVDEAQRRRERALLEKTRGPVKKVKVQRSAKDMRARLIPPMDQLHQAILEWDIFHEGNDPPSTSSSMAITRVASSYAHPQEYKQTFLGLLISEAWRSFVTAKDESTSKPYGLKIASRMNVDKFLEVTASIPKIESKERLLSEGDIILVSTSTDPLTDKSEAHALARIWKTTYKKERLEVTYRLNSKNNPLLAINALGVGAELQAVKITNMTTIEREYAALESLQYYDLMLEVLKAEPSPILKYGDEAVKGVMQNYQLNPGQAKAILGAKDNDGFTLIQGPPGTGKTKTIVAMVGSLLTGNIQPPGTAIKPKLPTQGQAAMPKKLLVCAPSNAAVDELVLRLKQGVKTMTGSFHKINVLRLGRSDAINAAVRDVTLDELVKKKLEGDTTQNKAKEERDKMHNDAAKIRDELAELRPKLDEARKNGDRNLSLALQRAFDQLKRAQINIGAKIDDDKTSGNTVSREAEIRRRQIQQEILDGAQVLCATLSGSGHEMFKNLNVEFETVIIDEAAQCVELSALIPLKYGCTKCILVGDPKQLPPTVLSQSAARFGYDQSLFVRMQQNHPDYVHLLDRQYRMHPEISLFPSLEFYEGKLVDGEDMSALRRQPWHASALLGPYRFFDVEGTQSKGSKGRSLVNHSELKVAMQLYERFKTDFGRNYDVRGKIGIITPYKAQLQELKWQFSRRYGESITEDIEFNTTDAFQGRECEIIIFSCVRADPTGGIGFVKDIRRMNVGLTRAKSSLWILGDSRALVQGEFWNKLIDNAKQRSLYTKGDVMSMLQKPSVLQALPPPPKPEQKNDLDVEIVDQLQIKDVDMASVAPTAQPRKPSQPAQQPPTNYPVPERRPGSWEGNNRGEAHQSAARNSDRPPIIQSSTAKQESKKRPSDANEGQRGAKRVCDDTSSDISRHSSSAIPNTTIIDGDRTEPAAQQTATDGTQSYDPGQGAEGTKAGEGPFCHGSPRSDTSCTTAGDGDDGIVFEDVAYQLFTSSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Z5</accession>
    <name>A0AAD9D2Z5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Armadillo-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371210.1">
        <property type="nucleotide sequence ID" value="XM_060503781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2Z5"/>
    <dbReference type="GeneID" id="85387680"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="767" mass="82657" checksum="FCDB007398CEF31F" modified="2024-05-29" version="1">MNFLKSAVASAIAQGPPFPYSFGDKVDIDESIWTLSNGTKREDGSNCSIFSFDVAANKSRLPLAKNALRKLRTLRHPGVIKVLDTVETDTYIYIATERVVPLRWHVKRKSLTPETIKWGLSSVARTIKFINDEASSIHGNLRVGSVYTSESGEWKMSGFEVLSNVKDDEAVIYTYGSLVPDSGRYAPPELARGGWDAIKKSPHSAVDSFGFGCMIFEVFNGDFMGSDQAGQTKSIPPTMQQSYKRLVNPNPKARVSVGHFLEQGQRSGSFFDSPLIKLTEGIENLGVKTESEREAFLDDLDQLTDDFPEDFFKMKILPELIKSVEFGGGGPKAFSVVMKIATKLSNEDFDSKITPVVIRLFANPDRAIRVCLLDSLPLMIDRLTQKVVNDKIFPQLVTGFTDVAPVVREQTLKSVLVIIGKLSDRTINGELLKYLAKAANDEQPGIRTNTTICLGKIAKNLGTSSRAKVLIAAFTRSLRDPFVHARNASLMALGVTGDCFSDEDVALRIMPAVCPLLIDKEKVIRDQASKTMDVYLKQVRKAASNMPETALPPQAAEGAGGPRMSTPQPNEASAASWAGWAISSFTNKISTANGEMQTSNGSGAVSPKPSPSPGPDAKRTTTSSASALHRQAVKSPPPMSRTPSSVVADAFDPEPADDGGDAWGDLGDDDGWGEPSANSSSSAKKATTASATPFDDGAEPDFAGWLAAQSQKKTGGSKPLPKGLSKSSTTAAKKPLVSRPAAKPVVAKKIDMKPKDDDDDEGWGDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D322</accession>
    <name>A0AAD9D322_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_597312</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372017.1">
        <property type="nucleotide sequence ID" value="XM_060506898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D322"/>
    <dbReference type="GeneID" id="85390797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="593"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="597"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="706" mass="79378" checksum="1AF9AB58EBDD770A" modified="2024-05-29" version="1">MAPPYSNGNGYAYKGAKKPASASASLPFQHYYNDDSFRARLRPLLAALRRLLRTLWAFWQTRGRRLATGIMWQAGRRLRQNLTARRLLSFPHLLVCLWGIVLLWGEGWVFKSRVAECKWSNWENWPAGSSPHHLVFVADPQITDPKSYPGRPWPLEDLTVLITDNYIRRGYRQLQSQLRPDSLFFLGDLFDGGREWKTAHSDFKDPQWAVNRRPKNEKDHVKGWNDNYGQKYWLKEYERFGDIFFGSWGLGGSKAGDWQRGRKLVASLPGNHDLGFGDQVKGSVRDRFNTYFGDVNRVDVIGNHSIVSVDTLSLSAVSSKQGEVDLKAIHTPADVFLKDVQFTKRKAVERELRFWRGEVEVEPLDHIVEELETADAKVPTIAPGEEGPDFPTILLTHVPLYRDPGTPCGPQREHWPPTKPPKGEQAPMMDHRNAISVSGGYQYQNVLNEDESVKLVKSVGNIVGVFSGDDHDYCEVVHSAEKDNVREITVKSMSMAMGVPTPGFLMVSLYNPIDANGKPLPGAPEKTLQTHLCLLPNQLATYAKYAGLAFVTIVAISIRSFLVPVLNLTPFALHDEQPQGAILPTIKDKVEDDGTYSMHSTSASSGSRFLTGQSSRTRSGSIRSNGTTPVPPPRTKLKKQWGAPHRAPRIEIFADEYGTGMPRLTWKAASQRSRTTIGRVAREIGASTWRVVWMVVLFWAYLAYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D323</accession>
    <name>A0AAD9D323_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_6297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371883.1">
        <property type="nucleotide sequence ID" value="XM_060508775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D323"/>
    <dbReference type="GeneID" id="85392674"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="65522" checksum="858960E7DC9C83A9" modified="2024-05-29" version="1">MREMITRYTYHGGPNEHKGPSDFNGGNDEDEDEDPEGTPPQESHMIPPQFQGQAPFPHMRHHTPSASPPIPNGVPFPQHHGLPVQRGHTPQPGMGSRPGSRQDIRRMGPNMGPQPVGPPGSQQPPVNGFAYMPNPAIYNPQNQPNMPPNMPHGIPQQYQQHGPQYSSYAPNHHPPHMQQHMEDQRRSMPPNYPQQQGPQGPGPQVSRISPSPPQPPTQQLPPQPPQISPPPQPQQLEPQQQQQQPHPSPQPQQQQQPQPPQSQQQQQQPQQHQPSPPQSEEMPAPSEPRSELPQRPQPPLLNTDSAIKKLPQRKQHSIFTPIDENRSILSQHLASFASEQSIKAEPNRPPFPDQSTIKVEGNRSQSVDVGAVSRTNGSTTSPPMPPRASTQSLNKSRNISVSSIPETTFTPPSRTNSMKLGGGARPRLRVEIPDEPSDGGSATAESNSPRNSTDTTSQTTRRHASDSHSSGMVLPPPSPSAQTLLSAGATGPPNPFARPPPQQNSNMNIDTPVSALPSRFLNNEFLPSPSSFYPEWYARGGSDSNTLPSPLNFATPVVGSGPSFLRDDNPATKRKSPEISANGPHDGPEAGNEPKRIRVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3B6</accession>
    <name>A0AAD9D3B6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_245856</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371376.1">
        <property type="nucleotide sequence ID" value="XM_060501898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3B6"/>
    <dbReference type="GeneID" id="85385797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232114" description="Mannosyltransferase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="516" mass="59084" checksum="8B515C9F0F542F95" modified="2024-05-29" version="1">MWRRAYLFLVLVRLWFALSPSYLHPDENFQGPEVIAGQIFSYPVRHTWEFTNEHPIRSVFPLWPVYGLPMMLLRWLWIGNGKDGEIPPIAVFWTLRVLMFVTSFVLEDWAIHELISSPRHRRVAVLLVASSYVTWTYQTHTFSNSVECLVVAWCLVLIQRIVESPQQSSLLASTILGIVAVFGLFNRITFPAFLLIPGLRLIPHFLNRPMSFTVMVLAALTTTLVAITLDTAFYLPEPIKWADLISRPVITPLNNLLYNIDTDNLAQHGLHPWYQHLLVNIPMLIGPAAMLLFTQPYLSLRLYSAISGVFVLSIFQHQEARFLLPTVPLILSSVHVPKNRTVLRVWIGVWLAFNLVFGILMGVYHQGGIVPGQVFLSKQPDATQAVWWKTYTPPIWLLNGKNEVLTTRDVMGMKGDTLLEELTKLATCDTPADRRNSEYLKEKNGTYLIAPASATWIDPYLPNKGLKGLRFREVWRYRQHLNLDDLDFGDDGIWNTLTRVIGRRGLVAWRVTKSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U499</accession>
    <name>A0AAD8U499_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_595800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000322">
        <property type="protein sequence ID" value="KAK1702072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357092.1">
        <property type="nucleotide sequence ID" value="XM_060506824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U499"/>
    <dbReference type="GeneID" id="85390723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1702072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="162" mass="18134" checksum="C01B4CF13E1E3575" modified="2024-05-29" version="1" fragment="single">GHSAYDVTEDGNEYSVFTNGYERGRIAVTRVIIKKPKTLEIKTAYNGQDKTDSKLHLNQILMALWMEKGGLRASSLKRVKFLEVANDSVKSAIQAARQELELEDVDDFELDVEDADEDLLSNFRNCVFGKVVARLCQASGHTPESISVEHTAGWDDITWDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6C7</accession>
    <name>A0AAD8U6C7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_714448</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000304">
        <property type="protein sequence ID" value="KAK1702628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357168.1">
        <property type="nucleotide sequence ID" value="XM_060511655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6C7"/>
    <dbReference type="GeneID" id="85395553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF53">
        <property type="entry name" value="ALPHA-GLUCOSIDE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="63"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1702628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="62534" checksum="497A1EA2DDACBD6E" modified="2024-05-29" version="1">MADNEKGLPETLAKARSRSVDHAEYGTYTPDIALIQAAAAASEEETRLPRKELISRYLPAAIYSMLLSMALIMEGMDVGLVNNFFGQKAYLRRFGWPDANGKQHIPTSWQAAIGNGNNLGSIIGLLLNGWLQSRYGSRRVYMGAMALMGGTIFSLFFAVNVQMLFAANILCGIPWGIFQTLTTAYAAEICPAAMRGYLTAWVSMCWGCGSFLAGGVLRGSLGLQGDLAWKIPYALQWVWVVPLFTVGFLAPESPWYLVRRGRIEEAEKSLRRLARKNFYTEQTMAQTLALMRHTNEMEKIESAGASYRDCFHGTNLRRTGIVAMAWLIQILNGQAICAYATIFLQSAGMPEVRAFDFSMGIQSGNIVGTAIAISLMGRVGRRVFFFWGSSIIGLLMLVIGILGFIPGKTNVALAVAVVMIIVNLTFKLSLGPTTYTIVGEMSSSRVRAQTIVLGRAIYVVGQIVVQQLNPRMLNSSSDSWNWGAKTGLFYFGLCCLWAVLIFFFLPETKNRTFAELDYLFQKRTPARQFATTPVDLFELTGGDASANKLDDDDLNKNVSELHEKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7L8</accession>
    <name>A0AAD8U7L8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_683261</name>
        <name evidence="6" type="ORF">BDZ83DRAFT_711170</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358918.1">
        <property type="nucleotide sequence ID" value="XM_060511229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7L8"/>
    <dbReference type="GeneID" id="85395128"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1710857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1710858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="296" mass="33553" checksum="1E61E83AC910E87A" modified="2024-05-29" version="1">MMNFPLLYSIWVRVEDFLCHMEGSRTSSKNGLQQYDEWTYKAWVRNKDPDRKSQFPNLLNVMVSAGVPTQTALSEAKENLGPGTDTTSASLAHILYALSWNPTYQQKLYQDLASRGFPTDFNTLENIPRLKACVKEGIRWAGASVAMLPRVVPKGGVELCGNFIPEGTIVTSSPVWYLRDKYAYPNPELFNPYRWIDDSGLNATEDILRDKFYVAFSKGANTCIANHFSYLELYMSVAKMVANFEISPANGRQRPAQVTGLNNADWQPVQLPKRKEWVSAVVTEPLLIKIVPRRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7M6</accession>
    <name>A0AAD8U7M6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_757450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the tannase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358932.1">
        <property type="nucleotide sequence ID" value="XM_060514899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7M6"/>
    <dbReference type="GeneID" id="85398797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF8">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041770605" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1710872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="59317" checksum="F1F2F9534EE8ECBB" modified="2024-05-29" version="1">MASIRGWICGFLVPTTLAQWADPGLTQVAFGANNGCEEGSIQYPALEGINIISLTTTEQRNFTYKPHPRFRFGREIHGLNFCNITLVYTHPGWNDEIEVTTFLPMEKWNGRFQGNGGGGWVTGGIEVGGITMMPSLEAGFVVSTTDGGHSSKLDEASGNDMSWAFTSPGSINWPLFLDFSHVALHDMATIGKALTEAFYGAPPKYTYFYGGSTGGRQAYMLAQRYPNDFDGILGFCPAINWDKFQWSPLWAHRVMDKKGVYPRPCEFQAITAAAMKACDGLDGAEDGIISMPSRCFFNASTLVGRPFDCGGNDALFTLEAAEAANAAWNGPQSVTGEFQWYGYGRDAIMWQFGALHTSCDGKGEKCAPVRLSIAESYARYFVAKNANLDLQALSHSQWDDLFVASRNEYESITGTSDPDLSRFRKAGGKLLSWHGMADQIIPVNGTVDYTDRVLKKDPKAHDYFRMFLAPGADHSISNGLAPRNTLSALIDWVEKGIAPVTLRVEGLNAYGKHMTRDICMYPQVQHYVGGDPALPSSFACV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8R1</accession>
    <name>A0AAD8U8R1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_686302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000276">
        <property type="protein sequence ID" value="KAK1703667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357330.1">
        <property type="nucleotide sequence ID" value="XM_060511261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8R1"/>
    <dbReference type="GeneID" id="85395160"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF96">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE STCB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1703667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="34486" checksum="02C49A7DC411E38A" modified="2024-05-29" version="1" fragment="single">MLFTDPVVVSWALVTTCVLGFLRLYSLWLSNPLKHIPGPWYTRITHYKLKWQTTIGRRMYYVHSLHKKYGAVVRISPYQVAISDPDGFVAIHRIGSGFLKSPWYEEFVGDSGIGIGVFATVDPVKHSVMRRLFSRAFSTTSLRQNCEDVVREKVAKAIQRIKGEVTHGSCDILHWLILMTSDVIGQLAFGESFELLESGKKNEYIDTFQLVGIGSFLKYELPWLHALSHYIPLKSLRRMLNAGNSIHEYGGRAVENLKRHRDNKSNLFATALAECDAGDKAELTENYIQIEASNLIFAGADTTAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8X0</accession>
    <name>A0AAD8U8X0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_637852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359656.1">
        <property type="nucleotide sequence ID" value="XM_060509331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8X0"/>
    <dbReference type="GeneID" id="85393230"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042120753" evidence="1">
        <location>
            <begin position="21"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="333" mass="34896" checksum="5E0DCFA9CB020442" modified="2024-05-29" version="1">MKSSIITALVGGIIAQRAAATPADELFARQAGCNRDNCFRALLGSKPGPASASADCSSWMQVTETPCTSTATQTATVTSYTTTLANAYPGLKKMKREEIEARQALTTTAAAPVCTPKQNRPSSMPAYAETGCKSTIGTLVPTARYSSACSCDGITATTTTLATPVTTITVTTTVEAAFTPTATPTAFVLQGSGDRSLYVTVDGQGALRLVRDASVATPFYVDKAGQMRNLNSPDKVLVDYYQPDPATANDKVYSDLQGTGNYPITCSYTGRSDGAYYGNCQSSGSPTGNPVVYGFGYCPNQGGYVYMIPNNSNVRCAGGYAFLGFCLQAYTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T8</accession>
    <name>A0AAD8U9T8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MIF4G domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_644275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000247">
        <property type="protein sequence ID" value="KAK1705175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357559.1">
        <property type="nucleotide sequence ID" value="XM_060509745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T8"/>
    <dbReference type="GeneID" id="85393644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="624"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1705175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="846" mass="94620" checksum="D49414013B677CA9" modified="2024-05-29" version="1">MPPKPLALPTQLLKQIGAPDQSATSRSNPRWKSQGQNRKDRRKADRQSKKQRQTTTRTTSRDHLVQSHDPIDNHGKGNDGKRPFDEPEEPRSPAPKKRKREHVSKYQDENDDDDFQKPLLLNQPSRAVQERLAKDDAEIEQLERKLGLKKGRKSIPKAFKDDGLDDLLGDLNDNNASDEGSHRDKSEADAWLAAKRRKATQDQAKIRSTTGSDDDDDDDHLGFTDEEASGEEDDEDDEDGDGIFMEDQGDSDDQSSLGDFDSEDEETVQESKPIRENPYLPPVSAGTQLPKYIPPSLRARSGGDADLEAQIRRKLQGPVNRVTEANLVSIVGEIDRIYQDNPRGHTNNILTSLLMAQICDPTSKPDTLLVLSAGFVAALYKVIGIDFAAHFLTTAVERFQDERHRAIVAVKEDRIPTKETSNLLTVLAQMYMFRVVGSNLIFDFVRLLLDDLSELNAELLLRIVRVSGPQLRKDDPLALKDIVSLIRPAVAKIGESNLTVRTRFMVETISDLKNNKIKAGAQDLAILGEHVTRMRKVLGSLDTQKLKASEPLRIGLKDIENADKTGKWWLVGASWAGQDTRETNKDKERSATVGDSDDMVVADADDLATHDYTQLAREQGMNTDVRRAIFIALVAAADYQDAYMRILKLRLNKYNRREVPNVLLQCSGAQQHYNPFYTLVSKKFCTDSRIKHAFQDTLWTLFRRLGEPLFGEEAEEEDEEGVDDRRLINTAKMMGSLVADGSVSLGILKPLNLAYVREKTSLFVEVMLITVLQECSHVKGKSLEQALGVCFGSGLAPALARSVGYFLRKKVRSTDLVSGKKETRKVKEACKVAEALLEKPDMGEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAG0</accession>
    <name>A0AAD8UAG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000288">
        <property type="protein sequence ID" value="KAK1703229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357246.1">
        <property type="nucleotide sequence ID" value="XM_060515112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAG0"/>
    <dbReference type="GeneID" id="85399010"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="14120" checksum="416170A13B198D07" modified="2024-05-29" version="1">MAAVQGRDGVQGGSVRPQLPQGLSITRPRENPQNTSPMQEQNLELETYLSENFSTLQQILSDTTDRDEAFHKSFESTLTNLTERVEKLGVKVESFYKLIESAQAFPAPEVLDTDGVDLGDMTNLVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBD0</accession>
    <name>A0AAD8UBD0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_594167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000238">
        <property type="protein sequence ID" value="KAK1705641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357665.1">
        <property type="nucleotide sequence ID" value="XM_060506697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBD0"/>
    <dbReference type="GeneID" id="85390596"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092702" description="WSC domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="38"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1705641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="29500" checksum="A52EFC0418C4E9F8" modified="2024-05-29" version="1">MKYSVAVLAAVALGFSSAQTATTTSGYQKPSEAARPGAITNHGCYNASSTTWTKYPVENISTGSCTLECQTKQKKNVAAINGEDCYCGDSYPPKVDVVDDKKCNFPCPFYPEEACGGVDDMMYYSVFNTGLKLVVPDEDVATTTTAAATTKATTTTAANGVVSTVIETPVATTSAAATETPKKSTNVAGIAAGVVVGVVAIAAIVGAAFFFVRRKRNAEIEEEHRRNAAVNAFIGGSKPPSSSGVSMSDSRMDPTLAHRRMSDGSIADNQDYSRKILRVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBJ8</accession>
    <name>A0AAD8UBJ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_586318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361006.1">
        <property type="nucleotide sequence ID" value="XM_060505933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBJ8"/>
    <dbReference type="GeneID" id="85389832"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="75"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="437" mass="48851" checksum="053D4D72D751A4E3" modified="2024-05-29" version="1" fragment="single">MVKIESGEYVKAHAEKTSSLRLEDLSDSEKGEFQIPKTWLKEHDTDPTIDCLRSLHATSGDYESQRIGIEKPVPGTCQWFLRHPKFADWVQSTSSSLLWVTANPGCGKSVLSSFLVDALSQDKNQSIVCSFFFKAGVDSRRDSHQALCVLLHQLFVAAPELVNVAMEDYSSKDKSSFTKDLEALWAVFRTSASRLHGRKIICVVDALDECSDESRNRFISQLVGSFSTSNSEKPAGNLKFLVTSRPWPSIESRFRNLLSIRLRGENESSSLSKDVERVVEHRVRELKMSSALSEDASTMVTKALTEGADRTFLWVSLVFDAIERLQSRKLSSIAKSLDSLPDDLDQLYESAWAAFIDHEASHKLLGIILAANRPLKLEEINIALSLGVNITSLEGLEQELEPDAEYTIKQLGGFFIRIIDSTVFLVHQTAREFLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBR3</accession>
    <name>A0AAD8UBR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_591305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358860.1">
        <property type="nucleotide sequence ID" value="XM_060506423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBR3"/>
    <dbReference type="GeneID" id="85390322"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="61086" checksum="29D87593EC524BBF" modified="2024-05-29" version="1">MDLVRRDGAERSQPYSYSVVGFLDSSQEIEYVQCRGRCQHDEKRIGCHLDCYSSISIETFSQTYEVTAPDFEPSHIANCQRSRWLRSWLASIIRRATHSRLPLEVCSDIAVRALDQQTSRRMAVWYAERKCGEFARNVSQVALSKKIYVRYAYFEGTRYIARLTNAATNNRDILVFDPLSQTPAARLYVSSDHLGIRQLLFVNSSSKPAIIQEPDVWWKTICLGIAWGLPQAVYKHVRLEPLCNAELTYRMSVVPCNHPTTTAYSLCWNQSILTLHAHTAGENFDCYHELRTMDESALWFYMPLRVGEVVTEIWKCDGSLRSAIALLLVTNRERSSYLGVQPQQGWSRSKWTLLDRPTKSPSTIYLMKTALGSLLGFESPKPDDHNPSPRVGWPTSSYPKSRRHEYFAWTSAKLDDVVDIIPCRRYRQGSKTISGLLLRYIDGQQACVGQIRLDQLQNPICVDRDCKMWFEFSLTSDGPIVSGIEQSREAPSLSKGENWFRVDWRGDLEWWYSKRQCQLSHQGRLSPETMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBV7</accession>
    <name>A0AAD8UBV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LysR family regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_593513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000219">
        <property type="protein sequence ID" value="KAK1706935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357935.1">
        <property type="nucleotide sequence ID" value="XM_060506632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBV7"/>
    <dbReference type="GeneID" id="85390531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF69">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1706935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55704" checksum="4E1F01C874C51B3F" modified="2024-05-29" version="1">MGSIFSKTTPKAPATVATDTIIPLNANDDTAFNRGIVMGFMMRFDNVLNPERLHLSLTKLLGREGWRKLGARIRLNSQNKLEYHVPELYNSERPAIAYSHQRHDCSIKHHPLAARLPRATSGPAVIGTPPEKFQDLMRRPDGPKSMQDYIYRDEPQLSLHIVSFDDATLVSLTWLHTLWDGIGRQELLTAWTAILEGRDDDVKFFHGFDTDPLEKLGKNFTEPFVLADQRLSVWGLVRLVLRYVWDILRHPFEESRIACIPAAYIETLKKKVNQELSEQSTGPDKLFASEGDIVTAVIGRLWSQHLPANTNKPIVLGNVINIRPALAQDILPEKAAFISNATSLIITTITAEDLWTKPLSYTAAAVRRSIQEQGTKAQIEARKALEKKHSAAFFGDKKMHQILLSNWGKAKFFETDFSSAVVEPRLASVTEPHKLGSPSLILNANYVRGYPLRFAGPIIGKDLDGNIWWGGTLRTGLWDRIAQTLEDQGWYLVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC01</accession>
    <name>A0AAD8UC01_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_591433</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358791.1">
        <property type="nucleotide sequence ID" value="XM_060506436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC01"/>
    <dbReference type="GeneID" id="85390335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="225" mass="25111" checksum="2F948F2265151BC2" modified="2024-05-29" version="1">MYQPYAVNEAPRERPKILCLHGGGSSAGIFQIQLIRLSRVLEPRFEFVYLDGPIETEAGPGVLPVFEGCGPYRRWVSDDPSIPAEEFQQQKDTAMEMLKVYVQQTGPYVGVLGFSQGARAASSLLIEQQRQPFVPYNFFGVFLCGTYPPFVPDDVLIRLPTVHVVGLFDPWKPASEMLIEQCSERSTRKVVRYPGGHHLPNAPEAIQNIANMVIDLWKETTGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD76</accession>
    <name>A0AAD8UD76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_641242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000180">
        <property type="protein sequence ID" value="KAK1709699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358610.1">
        <property type="nucleotide sequence ID" value="XM_060509541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD76"/>
    <dbReference type="GeneID" id="85393440"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="91"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="554"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1709699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="580" mass="63122" checksum="A891DDF700C0EDDE" modified="2024-05-29" version="1">MRRWPAQRSDQRQEEIFELSANELTTATLTLDSPNHHNQHLGTPDCQSTVTVEPQTQTPTVSPAENSSLHPEPFAIMALLTPGPIISHVLMVLVAMLNICILSYDAGMINNLNSVKPYQDYFKLNSDMIGLNVAIISAGSIFGAPIVGPVVDRWGRKTGLAVGSICIILGVVLQASASKVPQLIVGRFIIGFASLINGSIAPMWVMEVAAPKYSSILSSTVLTSVPFTSFLVSCIVLGIYDKQSDWAWRGLMLGEAVPSIISLSLLPFVDESPRWLFSKGRHDEAIGVLARLHANGNREDALVLSETQEIISALNHEKESNGGWKDLIAPSPNLKRFTIAVLTNIFYQILGGNMILYFSSFLIGKLGVSERKSVIQINIGLLLWKAFCSVGGVLLIDKIGARKPLITGTSATVVLFGILAGLSYLTEVHPETNAYAIGAIVVVALFLLAVAASWSILAYTYPPEVLRYSQRAKGVVVAQAIGYAFSFLNLYTTPLAIERISWRYYAINGGWNLGILFVVTWLFVETKGRTLEEMDEIFDGVVYSNNVIIDGQNSKSDLGKDVGDSSSVAKRKLSKASTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDD0</accession>
    <name>A0AAD8UDD0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_633476</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360947.1">
        <property type="nucleotide sequence ID" value="XM_060509040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDD0"/>
    <dbReference type="GeneID" id="85392939"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02662">
        <property type="entry name" value="Peptidase_C19F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="152"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="669"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1717460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="699" mass="76694" checksum="FFCCB9AD1A9490A2" modified="2024-05-29" version="1">MNSPAFKHSYGGSDYHRRLHADETIWTRLTEPSVVVSLFALVLTALVSVFGASLPTTLLSHASRTLWDVIVWLIPHDALTLLEAWLHPPLVPRPMLQNQARTHAAKSALLKKILGMDRQGGIMGTVSQAGIRGLSSVSGAMMSLKGSSNYPPGLGNLDNSCYQNSILQGLASLKPFPKYLADPVQHPEIDRRKVEAVDTLRNLIEDLNSASNYGKTLWTPGSLKNMSTWQQQDAQEYFSKLLDEVDREIAKVAKATIKASGFETDCASDDTATSQHSDDSGYQSLSTASKISAASKSLRNPLEGLIAQRVACVECGHSDGLSMIPFNCLTLSLNVGGNDHDLYELLDAYAHIESIEGVECGKCTLLKAKRLLTLLVERAEASYTDEQKLKEPKSRLAAVEEALEEDDFEDKTLTEKCKFPSNFKVSSTKTKQAVIARPPQSLAVHMNRSVFDENTGMMYKNSSGIRFPLTLDLGPWCLGSASKTSSTDGLEEEEQWLLDPRSSMIAGDKRKSYITGPIYELRAVVTHYGRHENGHYVCYRKFPRHSPPSDGEEVVSPKSETLDDDPDAEMDWWRLSDDTLRKVDEEELLAQGNVFMLFYDCVDPNIIPSSEVAAVEAVQDADAMDGENEETPKVEKPAFTCTVKEVSADDDDNEMPVAGTMVAVAEGDVSQARSVPLPGGGDDELGENQTERGPQMIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDK6</accession>
    <name>A0AAD8UDK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_734769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1712997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359613.1">
        <property type="nucleotide sequence ID" value="XM_060512953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDK6"/>
    <dbReference type="GeneID" id="85396851"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF9">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1712997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="55744" checksum="E440AA794B1B27A0" modified="2024-05-29" version="1">MATESKVPIKSDEDLKRGSSDDVEAASSLHSAQNGSSVVVDPEGERSYVRKLDFYLLPYLSLMYFFNAVDRSNLGNAKTDGIEKDLNFKGNEYSLLILLFYIPFGTLDLPLNLLTKKFSARWVLPTLMVVWGGIATVQIASKNFAGILVLRLILGACEAGFFAGVVFYFTLFYKRSELGFRVAIFFGSALLAAAFSGLISYGVFQIEGTKLQGWQWLMLIEGVLTVLVGVVAFWWLPASPATAWFLNDREKAAALARTLRDGSNKVDTKFDWKECFTLWKDWKFVFWLSIAFNYPVAFATTSNFLPQIVQRLGYSVVKTNLWTVAPNAVGFVILLATAYSSDYFHERTFHIVGALATSLVGMVILIAIDVLENRELAYFACFLMAAGAYTPSCLVQSWHNNNNLNENSRAATTGLLVGLGNFAGILSAATFRTEYAPKYIPTLIVTCCCNVLAMASALILGGWMKLENRRRNKAQGVNLQAQDVDTSELHDGEKSPKFRFFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDR0</accession>
    <name>A0AAD8UDR0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_23322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361048.1">
        <property type="nucleotide sequence ID" value="XM_060501822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDR0"/>
    <dbReference type="GeneID" id="85385721"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF15">
        <property type="entry name" value="LIPID TRANSPORTER ATNI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="380" mass="41878" checksum="A3A2310141B21C4F" modified="2024-05-29" version="1">MATPTPTSASPASVSSSDSLPSCTTAVPGKYGHVPIDACNSYYAFDPSFGGNVAFAVLFGLSFIAHIAQAILYRKRFCWVLCVGASWELIAFILRSLGARDQQQIGYQIGGQLLFLLAPLWINAFAYMLSARLVYLVLPDQRVFRVKATALTKIFVTMDVVCFLVQGAGGAMMSNTETASDDPILRTGKQVYMIGCGLQLAFIVVFCGLMGRFYAKMRRAQRFDLDLKRIGAIVLVMFVVLVLIIIRIIFRLVEFGPGANMDNPILTNENYAFGLDALPMVLALMLLNAVHPGIVLRGENSEFPRLSRKEKKQVKLERKAAKRESKLAKKVAREQNKKDKATGLEVDSDEGNYVAMEERPLAADEYDSDDRTGGRGSHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEI0</accession>
    <name>A0AAD8UEI0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_756467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360066.1">
        <property type="nucleotide sequence ID" value="XM_060514753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEI0"/>
    <dbReference type="GeneID" id="85398651"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="545" mass="61915" checksum="37A3A2ADBC305EF2" modified="2024-05-29" version="1">MMPISVNVTVQKPLPGFKSDTTNTKAVQRRSTQQPTNRLRFDLNCRYYATRDDVPQCLTSLWRYLLLPKHQKQLAGWELLGRKLRRGQNIEDKTPKIVFLEMRFAHIWLTYDQMGVARRAFLDTMEALRDIMSGLARANADERGTLDWGKVFSFACHPRIAGECRRPWGIEPAGYYCHPLEQGGPSGSAQKATQELLLKYMEVTDPVCGMTLATTSSSVALREARRRVDRSDDNTQPLWNAILFSSVLRSDPLQLDVDLAVFTTKKVVKWYDELLSLCKVAVQSQGIESRVDKAVTLAKQLQVVSERETAASGRVSVTSESASEKTLCGEKDWGLGKVTVIEIEDVKDSARYENGEELAQPKKARWWRRVLASFVTKVQVSNRQRQQDEASKLVRRSLEISRIRTELSKSVVEFSAEVEQLRLAARGFILQLKLQTKWRQVQAVAQRPGVTMAEVSKVTTVNIDHLSCERRRTQAILEKVSKLNRADDAMMQGAREILGRSKRLNKELKSLHKDLKKHAYQYEPRASLGRRGTLSLAWGHVNVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF04</accession>
    <name>A0AAD8UF04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell wall glycosyl hydrolase YteR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_705497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361757.1">
        <property type="nucleotide sequence ID" value="XM_060511508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF04"/>
    <dbReference type="GeneID" id="85395406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF9">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202441" evidence="2">
        <location>
            <begin position="20"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="413" mass="46473" checksum="9BBE44428298CC5C" modified="2024-05-29" version="1">MKITTLAATALAGATLSSAAISLPNGWFAIAPDEKLKSGKLDGEPRYLTWMADSQIKHGVEPTYAYTISAFYSGVLRAFERTGDKRYYNYVKHATDILLYPSQDGEILLYNNSNSIDDIRFGHTFLDIYNATGDEIYKTAAQTLRHQIDRTGRSPDGGFYHRYPVYIDQMWLDGIYMLDVFYARWIAEFEPDNTTAWDDIALQFDLVTAGTILGNATNGLPLHGFDWSKKAIWADPETGASPNVWGRAVGWYVMALVDTLELFPLNHPARERLIGYLQHVSDAVVAAQDEKTKGWWLVMTPGTEGQWGNYIESSGSAMFVYGLLKSLRLGYIEGETYLKSALSGYKLMTDTFSDTRKSDNALVWGWTVQTGSLSSNGTFEYYASMPLFENDLKGVAPFLFSSYEYELYLEQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFA0</accession>
    <name>A0AAD8UFA0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360720.1">
        <property type="nucleotide sequence ID" value="XM_060506005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFA0"/>
    <dbReference type="GeneID" id="85389904"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="57"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="58242" checksum="EAA632555E170B11" modified="2024-05-29" version="1" fragment="single">EDRTLCARTWLNTCESTHGSYCQPRKGELPKRFIDTIPGQPLRLVHTSQQLSGSVRYATLSYCWGVSIPLRTTKVTDEHFSVSIPENLLPRTFRHAIKFVRSLGIRYLWIDSLCIIQDDQAEWESEASRMGDFYAGSLITIAASDAWDSEGGCFPGEDDSMEAVIDDKGSKNGYSQKFCTRMIRFQSLDPREISRQAHLSTRGWALQERILSPRIVHCLKSGVHWQCQYLYETQATQTYELHHFTASDSIYPISQISQWWPEWIEDYSKRNFTIASDRLQAFAGITKHYTNLTSKKPILGICPGNLARDLAWIRNGHIKGPGVCGAPSWTWFSCNAPIMVDDWGFKLQRRFKVSNDVELVAFGIEWKGIPMTSQIESCHLIIRGVVKSISVRIPPEAMIYNPPYMLLNHEETDFSKGPIPWTCSGRFDDPGHPTDSRLSYPCLLLRTRIIEEAKGGTLFKETFLILSRDNESPRAKSTEHIRFRRIGIASSRGKDRLFADDIDRETVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFE2</accession>
    <name>A0AAD8UFE2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_587390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360573.1">
        <property type="nucleotide sequence ID" value="XM_060506034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFE2"/>
    <dbReference type="GeneID" id="85389933"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015489">
        <property type="term" value="F:putrescine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="631"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1716179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="655" mass="70709" checksum="F236F283BC6628A3" modified="2024-05-29" version="1">MDSTPVLHQGWGYGLMIGLGVLFAVFMIIITWALKRYNYELQTSEMFTTAGRSLKSGLVASSVLSTWTWAATLLQSTAVAYKYGVSGPVWYASGATVQIILFATLAIELKRRAPNAHTFLEVVKARYGPVTHGVYIVFCCFCNILVTAMLLTGGSAVIQNLTGAPVAASVFLFPIGVVVYTLFGGIKATFITDYINGLVILIIIFIFAFTVYSTNQLLGSPGRVWEILTELAAERPLAGNAGGSYLTMRSQGGTIAASPIDALPGYVMGGISWFAVPWLTATTMGLAGLALERYDIWPTYPNRLAAADVDAGLVLPTAAVALLGKGGAVATLILAFMAIMSTYSSELISVSSICTYDIYKTYFNPNATGKQLMRINYIGMGVFALVMAGFATGLNYVGISMGYLYLMMGVIISSAVLPAALTLLWDGQSWAAATFSPIIGFALSMTAWLVTTKIKYGELSVTNTGANEPMLAGNLTSLLSPIVFIPLLTFIPPFKPQQYDWQSMLNIRQADDHELVDAAHVDVENSPEERARALQSDPDEQVKLEKAAKTARWLTVGVTLVLLILWPMPLYGTGYVFGKSFFTGWVVVGITWLFASVVMVVFLPIFESRSTIVRTTRMMFKDLFGLRGKGKPVSEGMSPGSSTPPELTEKATSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFG9</accession>
    <name>A0AAD8UFG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_547569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360618.1">
        <property type="nucleotide sequence ID" value="XM_060503461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFG9"/>
    <dbReference type="GeneID" id="85387360"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF8">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="37"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="136" mass="15095" checksum="4276E0869E6AA742" modified="2024-05-29" version="1" fragment="single">IPTRLIDVGSTDLDVPRLVASDALHKENEEKLHGVEYATLSYCWGSREDAAEQLKTTRENLSEHLEGISLDSMSPVVRDTAITCRALGLRYLWVDALCIIQGDIEDWNTESLTMGRVYYCSALTICPLTSTSCLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFJ6</accession>
    <name>A0AAD8UFJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_654257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362158.1">
        <property type="nucleotide sequence ID" value="XM_060510703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFJ6"/>
    <dbReference type="GeneID" id="85394602"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="75"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="572" mass="60301" checksum="1A36F04449DC8D5B" modified="2024-05-29" version="1">MTSTTSTLVTPREKVGEKTGGETDRENTPTPSMLDEEVVEKKEEAGTATDEEAGSSQPTEPKEPEYPTGIRLTFIVVALVLSIFLVALDMTIVATAIPKITDEFRGLDQVAWYGAAFFMCVAAFQSTWGKAYKYFPLKTSFLLSIFIFEVGSLICGVAPNSVALIVGRAIAGVGAAGIGSGAYTIIGFSAPPDKRPTFTGIIGASYGIASVIGPLIGGAFTDHVSWRWCFYINLPIGGLSAAIILFYFHTPPQAVPVKASMLEKFLQMDLIGTALIMAATISFLLALQWGGHQHPWNSSTVIGLFVGFGLMIVAFIALEWYQGERAMIAPRLISDRTVYISSAYAFFFAGAYFVLVYYLPIYFQSVDNASPTQSGVRNLPLIIAVTIATVASGISISATGLYTPILVVGAALATVGAGLLYTLDIGTGSDKWIGYQVLAGLAWGAAFQVPIIAVQGTVSESDLASATAVLLFFQTVGGAFYVAAAQSGFLITVLKKVAENVPNVDPNLVALTGATQIRTAFPADAVPGVIQAYMDGLKVAFALAVAGAGISFLISLGSRWSKLNTKNLAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFW5</accession>
    <name>A0AAD8UFW5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_630012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362192.1">
        <property type="nucleotide sequence ID" value="XM_060508794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFW5"/>
    <dbReference type="GeneID" id="85392693"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041920938" description="F-box domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="44508" checksum="5F0907D71232283B" modified="2024-05-29" version="1">MASLLTLPLEILQQILAELADNQPEPPSLEYTVPLFSSNTTSAILCQTCRSLREIAEPVLHRHIYMRSASVKRFISLFRCWKARPHCAQYTRRLTIEARSRRHEGFAWRATTRLIDLEDADFVSSIIRDVGLKIRSDWFEHDWNINVLVEVAMLLAQNAESVELLFQDQRGVYRQPFDMIPPDKATKPILFNNLRHLHLMQPGPSSMDEFKSILDCTPNLQRLRLDFCGNPMSVFTLPPNLTSLILRRTNLGARQFQSMTSNFTILRHLELDLDGSSREKSILEAIAKHCSTLTSLILISGKALPFAKLKNLHKLKSLTTSIETVQPEDLLGSVPFSLRDLCILEETNGGTMHRPEAWFKDFNADLDARSGTLPQNMVIHKRIMFFGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGN2</accession>
    <name>A0AAD8UGN2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_755514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361191.1">
        <property type="nucleotide sequence ID" value="XM_060514626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGN2"/>
    <dbReference type="GeneID" id="85398524"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="92" mass="10230" checksum="2FFEA4E47EA00267" modified="2024-05-29" version="1">MTRAQQTISLALLVSSLYLALFLQLIPIPAKIQNDVVPVLPFWALISFGSYLLAKLGYNVMTFNDVPEAHKELMAEIEEAVVDLRKLGVDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGY6</accession>
    <name>A0AAD8UGY6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Family 13 glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_579451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364152.1">
        <property type="nucleotide sequence ID" value="XM_060505240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGY6"/>
    <dbReference type="GeneID" id="85389139"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000004">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000087">
        <property type="entry name" value="Oligo-1,6-glucosidase IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF232">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 13 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="3">
        <location>
            <begin position="19"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="66840" checksum="A181D29592F85326" modified="2024-05-29" version="1">MATSGPPDRQWWKEAVVYQIYPASFLDSNNDGFGDVLGIISKLDYIKSVGATAIWLSPIFKSPQNDMGYDISDYRDIHRPYGTVADAENLIKGCHERGIKVLLDLVVNHTSDEHEWFIESRSSRSSPKRNWYFWRDPKIDSSGNRHPPNNWASIFGGSAWTWDEQTGQYYLSLFLPSQPDLNWTNEDMRRATYSDMEFWLDRGTDGFRIDSMNLMSKHPDLPDAPVTRPDSEFQPGDLYYASGPRMHEYIREMREKVFDKYNCMTVGELGFTKDENSVAEYVAKDRHELNMVFTGDIVDMDFGKNHKYEHGDFRLSKLKNITNLWQKAMLKCDGWNAVYFDNHDSGRSLSRYASDLPQYRHEAAKMLAIYLGTLSGTLFLLQGQEIGMANLPESWTIGDYADVEGKNYYNSVLQKRGKNADMSDVLAEMRIKARDNGRLPMQWSAEAHGGFTKSSKPWMRVNDDYGDWNVERQEKDKESVLAFWRRILSVRQQEKDIFVYGTFSEVKDFEESEQVFAFVMESYEGKRALVLLNFSDEGQKLRLQNFDGWKQLLGSNAERIEGGNLELKAYEGVIYSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH43</accession>
    <name>A0AAD8UH43_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_756029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360560.1">
        <property type="nucleotide sequence ID" value="XM_060514692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH43"/>
    <dbReference type="GeneID" id="85398590"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052138">
        <property type="entry name" value="GATA_ZnFinger_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47255">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47255:SF4">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="5">
        <location>
            <begin position="161"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="23846" checksum="4D77352A9A24111A" modified="2024-05-29" version="1">MARTPADLVTPVPAVTWRRRPSENECSNANEPLAAMSLNHLKASETIQRVHGDANNLLRNIQGLLRYSRAPTLDGGRLLTGVLLNNPKLLHAQKISQHITGDMAELVAISQKSRETAVRLKRPNHLRKIRRKQHGQLEHAAAAAVNHHSNELQSMPDPSVCHNCHTTCTPQWRSGPAGPRTLCNVCGLIHAMRQRKQRLRHSNRVSASSSMSFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHV5</accession>
    <name>A0AAD8UHV5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_457455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361624.1">
        <property type="nucleotide sequence ID" value="XM_060503206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHV5"/>
    <dbReference type="GeneID" id="85387105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000066">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF20">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="27"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="406" mass="44834" checksum="28D8D30B7CC40B7C" modified="2024-05-29" version="1">MFGHVQPGPPDPMFTLKRDADNDTCTEKVDLGVGIYRSEKGSYQELEVVKKAKLELDELDLGHDYELTIGDADFLRLAAEVMFGAHSDALQTGRVSSVQTISGTGANSLGALFISKVMEPKPRIYIGVPTWGNHIPIFQDTGLETTTYPYLDASKHTVSFTALLDTVRSAAQGSIFVLQGCCHNPTGVDLSLSQWEELACEMKCYGHLPFFDTAYQGLGDGLDEDAAGVRVFVDAGIEMLVCQSFSKNFALYGERCGALHFVGNSQEVAANVQDRLRSLIRHTYSSAPAYGSRLVKIVLNDADLRKEWTSETDGMRKRLKRNRQALYDELAIRLKTPGDWSYLMKEKGLFSCLALSQSQCRELVETYHVHLPGSGRINLAGLSEENVKRAAQAIDKVTRIHVNGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ15</accession>
    <name>A0AAD8UJ15_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonase, 7-bladed beta-propeller-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_703623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362685.1">
        <property type="nucleotide sequence ID" value="XM_060511481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ15"/>
    <dbReference type="GeneID" id="85395379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060359" evidence="2">
        <location>
            <begin position="20"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="40563" checksum="58BB4CB09FED4415" modified="2024-05-29" version="1">MGRISHFLLCLTFLQGAFAATLIASHYSGQLYTLNLSSTNQLTITNTVSAENRMPAWLDFDPASKTVYIPDEVQRGQPLLKSFSVAADGSLTSKAQVQTAGGELHSTFYGSGNGYIATAQYDASTISTYGLPLGGTSQPLQTLTFTMSQPGPVPSRQDKPHPHSVFTDPRGKYLLSADLGADLIRVFSIGSSGILTQCTSFSTGSGDGPRHGAFRTQGNTTFLFTVNELSNSLTSWSVTYPATGCLVLAKKQTLSTFPPGKAAPAGSKAAEVHVKDNFVYTSNRNDQSFGTQQDSITAFSIDPSTGLVTYLETTSAYSFFPRTFSINNAGTMVAIGGQTSANVAVVERNATSGRLGKLLATLKVGNPGTVNQEDGLSAVIWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK40</accession>
    <name>A0AAD8UK40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_677011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362000.1">
        <property type="nucleotide sequence ID" value="XM_060511165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK40"/>
    <dbReference type="GeneID" id="85395064"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF11">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="552" mass="61838" checksum="94D7C56D10F4209D" modified="2024-05-29" version="1" fragment="single">MPSLDASSCALLLSSQNAIPTTPFWDAPFVSSAWTVDGHSPTTSSSQAEDREVEHLFPSESPVVDVQENSTLPFFDNTQTRPCKQLLESSPRELSHLPTSLSEYFFREVITLYCAWDSKTNVMRNIVETMWQSSGALYHTIQSMAAACLSEDFPHLLPVARREHGNALKLIRDRPSALPLSTSMTTTHKRAMLLSSTLLGHTSSWLSPQNLATDMFRASCSMLKDVSAETRGSDADASLSFFSDTMDYWAMLLAYLTDSTQLGDYHHTTSIGPADPSKSIEPHPYSGISHATVRLLTDTGILIFQYRKHMAAVKFLTETDLDVFRAALRSARQLERAFLAHRPPDLSRVTDPGDPKTPLRHLELIDEAYRCTGLLQLYRVFPDLLNERYAPWDRERLLRPVPMSAAAGVGVDSNKVPSARERRTWLTKLAMYILGILRDIPFESRTRSAQPFIMVAISSELRREPQHLRQPDAGYGDSGADVLDIGPASIEVARARKFVRSRLAAYTHILPLRKSRVISELIDHTWAALDVGEEDVYWLDIAREKNLGTMMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK72</accession>
    <name>A0AAD8UK72_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_751300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365907.1">
        <property type="nucleotide sequence ID" value="XM_060514034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK72"/>
    <dbReference type="GeneID" id="85397932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="474"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="413"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="528"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="698" mass="71365" checksum="CEBEC145EFEBB12D" modified="2024-05-29" version="1">MAHHHHHLHARRHIAPRNPDFWSNVGDKFKDLNPFASNDEATTSNGGNLKIRQDDDDDDATTTRRANTKKGRSTVIKTIYQTVTGNDAVAAPTSTTSTKLIVAQSPLPTRSKSTTVDSTETTIAKAGAPIIKTADSSSTTIDAASTSSLPTVIEDPLTESIQTTLAIATDAPTFAKTTKTAATADNASIISSASPSATSTTDKSTSNETSGAAKAGIAIGVLAGVLVVFLLVFFLFNRRKKQMEQQRLADEDEKSHGFGAAAAVAGSQNPRAPRISLRPVTQFLPNLNLDKRASRGPAGGPAVNMNANLAPAAAALGLRNPGQGAWDRPATNQSSNPANPFGAQAERINGPIAEESVSSMSLNEKPLPSVGEPAPGTAVSDIPANAAPNGAAIAAGAAAVGAGAVAVGGLARKASTRKDGPKALDLTLPAPPAPLSTIPASPSGTTFSADSAGPGHQSNGSTGSAAIAAAGGPANTTVHRVQLDFKPTLEDEMELRAGQLVRLLHEYDDGWALCIRLDRSQQGVVPRTCLSTRPVKPRPPQAQGPNQGPPRGPHMGPGAPRGPGPNFPPGQRPMNPQGGPPYPRPESPAGRPMNGGGRPQSPAGNGAMGPGGRPQSPGPRYQGPPGQRPQSPNGMGGRKPSPPGPSRIPQPSRMNPNGPPNGPMNGPMNGPLNGTPAQGRPGPPMGPVGRKPVPGQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKK6</accession>
    <name>A0AAD8UKK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_389595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363479.1">
        <property type="nucleotide sequence ID" value="XM_060502779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKK6"/>
    <dbReference type="GeneID" id="85386678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="153" mass="16585" checksum="C3828529D18E4017" modified="2024-05-29" version="1">MTTEISQISTCSFNIPYQFRILKYPAVLGKSIPPILNAIKVIGGASPSIMSSSTAAPGMAHHTATAASTQPRHPLPLQSAWERHHVATAETAMVQQQQQHNSSIRHPVFFTEKLRRPPLTLAPGMGLSPVAHGYVYQDGRRRLAAEGNSAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL86</accession>
    <name>A0AAD8UL86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_628579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362600.1">
        <property type="nucleotide sequence ID" value="XM_060508713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL86"/>
    <dbReference type="GeneID" id="85392612"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23520:SF5">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G04000)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="3">
        <location>
            <begin position="24"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="454" mass="49024" checksum="85BAE3CAB623AA9F" modified="2024-05-29" version="1">MSRQLLHRGLAETGLLALGRSHPDIKLLCLQRFVRMFAYGATTLQLVAYFELLGFSATRIGLFMAFTLVGDVCISLVLTSIADGVGRKAVLAAGAALVAVSGVVFAMCSGFWVLLGAAVVGVISPSGAEIGPFRAVEESIVAHLTTAEDRSDVYAWYSLMGAAGTAFGAMTSGWTAHYLTTSAGWGLEHAYRIVFYGYAALGVFKFFLALLLSRDIEAERDEAGVSEEEIAPILGERPPEREVEVKTWRSRLVPRIERESMPVVATLCFFFALDSFASSLTTQSWIAFFFRWKFNVDDGTLGSLFFTTSLLAAATTLVASSIAKRIGNLNAMVFTHLPSTIFTALIPLPRDATTAIVFLIFRALTHSMDVAPRAAFLAGVILPKERTTVLGLINVLKTCTSSVGPVGVGILVDKNLFWVAFVGAGCLKVVYDLGMLVSFRKHERELRDGTAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULC1</accession>
    <name>A0AAD8ULC1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363501.1">
        <property type="nucleotide sequence ID" value="XM_060505385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULC1"/>
    <dbReference type="GeneID" id="85389284"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="32"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="512"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="631" mass="69547" checksum="57694641ABA7D219" modified="2024-05-29" version="1">MQAISSDCDTSSTSFGQRRGISDLARFALDLTWATPTRAESETPARPRAYPSPPMSGSPPLPPKPNPEAGDRGQLHGSYPSTSPQNAYRGGLPPTTIPQGDYRGPPPPPHSLPPPQPRSYYADPHDRMPYSYPRPDDHLRTTASGYAPVASQVMQQRPPPPYMQMSGPPPPQPAGPHQHGYATTMSQTSQDSGPYTSPKTQRKTKGHVASACVPCKRAHLRCDAQRPCSRCTSNGKEDACVDVQHKKRGRPRLRDDREARYGPSTYQHPQDAAAAAAAARRPPLSHYSAGTPISGYDDPIRGSHSYRVLKSQPSEPIAPRYLDRAPMGEANLYSQPPSIASGAPEPVIFLTTELEIARASPSFADAVGIPSVRGRSLFDIVMPSEREKLQSHQRQIQEERTRKDPVYLPPIFGRQEQERVFDSLRFEADEISRFQLDRQDFFVFAASDGQPRSYSVRLGLAKRESIYFIVLLINAAPRYPYPSPSPHAREVPYPYPPQQQAYTQHTPVSATFEQPRPRFGEGALAPRPSPGQPLHMASGLSPGISPGMPSYQASPSRPEYASGPSSYQIPRSELPPTTRPPQPSFQLPPIRAGPHQPPQPESSSWQRDERSGRVDIGGLLEKPDPQQRRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULW1</accession>
    <name>A0AAD8ULW1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase OMS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_576987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365282.1">
        <property type="nucleotide sequence ID" value="XM_060504972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULW1"/>
    <dbReference type="GeneID" id="85388871"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF83">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="33406" checksum="A684DA988A93E55E" modified="2024-05-29" version="1" fragment="single">ISLLASSSYSSTYHENPEPAPDAVPTGRPNVFTKDSAKKFDQSLEGSEWLMGITSLRKRLAAEAFGHVLEVAMGTGRNLPFYDWSYVISSPKPATQALAAPEADAQPSKPDAAPMISYTGIDISDKMLGVAVEKLAETVPELADVDPRTEKQTAEWNDISYLAGRLRMFRSDIHEYIPSPPRQSCPQARYDFICSTFSLCSVRDPEQMVRDLASKVKPNTGKIVLVEHGRGWWGFVNGLLDKSAASHFQKYGCWWNRDIAEIVENAAQSTPGLQVTKVDRPYFTQLGTTLWIELRVSDSGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN61</accession>
    <name>A0AAD8UN61_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364431.1">
        <property type="nucleotide sequence ID" value="XM_060514223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN61"/>
    <dbReference type="GeneID" id="85398121"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042216320" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="56" mass="6018" checksum="4C289144C1A6F546" modified="2024-05-29" version="1">MRFNVISVAVTALAFFSQQALAQEACQSTADCIQNCGGFADKLCRLPGNICECVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNF2</accession>
    <name>A0AAD8UNF2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_351063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364566.1">
        <property type="nucleotide sequence ID" value="XM_060502525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNF2"/>
    <dbReference type="GeneID" id="85386424"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="204"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="319"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="430"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="500"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="527"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="595" mass="62051" checksum="999BA4A8B9CB70F0" modified="2024-05-29" version="1">MAEPPRDISSILAALGAAQRGTSSTPTQGQPGMPPSYPPPPGGQPPPSYPPMPQQNAPPYGGGGGYPGLPQPSSSGSLDLSSIRPVNSGTVSIADAIAQAKAFAAEKGVTSYDRPLVYSNEAPRGQDPRAYGRSSRSRSPSNRRDQFRDNFNPYRDERRDDRPAPRDYGHRERSYSPGPRGRTFSPRNSNGRERSPLRGSGGGDDNAETIQIESSLVGLIIGRQGENLRRIESESNCRVQFLPSSDNGPFRQCKISGPRAQRSEVKEAINRIIDDSGMGAINRGAANPKGPPPRDHRGGPPGAGAAAAAGAGAAALREGEDCMQIMVPDRTVGLIIGRGGETIRDLQERSGCHINIVGESKSVNGLRPVNLIGSRESAAQAKDLIMEIVDSDSRNEGQPAAPAKKPQRHDGGGHQRDSGPMGGAGGGSGDKINDAIYVPSEAVGMIIGKGGETIRDMQNGTGCKINVAQSSGPGEVQREIALIGSRDSIARAKQAIEEKVDAVRQKNSGGGGGGRGRQNQDYDRSYSQQGSNPSASGSANPPAAQAPAGADGADPYAQYGGYQNYLALWYQSLVYQQQQGGGAAGQPGAAPPGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNJ4</accession>
    <name>A0AAD8UNJ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-GTPase-TBC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_623367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364399.1">
        <property type="nucleotide sequence ID" value="XM_060508378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNJ4"/>
    <dbReference type="GeneID" id="85392277"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000055">
        <property type="entry name" value="TBC domain-containing protein C1778.09"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000023">
        <property type="entry name" value="TBC domain-containing protein C1778.09"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="274"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="61761" checksum="4E212BF7691084ED" modified="2024-05-29" version="1">MESRKVRSLYESGEGLRWEDGARPSDVGERLNSTAETPTEEVENDPYGFLLPGLVPNQYANVCSLCSVAELQPPVWGTPRSGSSYSQRPETRSEYEVAGGLEDWEDLEGYDIDRYGFISPRKPEKSNGTPAEPRSSQSAPRRKHVFSKRDAFGLGLPSRGPSRKVSARSLNTQGSKASVASRRSTRSAIRQAGNLLPHNRDRRWMDEAGEMLSLSLGDEEKVEKISEAIKKKEWERSEKWRKMAKIVKKGKDGEGMEFDFDVKNQKLIDRTWKGIPDRWRASAWYSFMATSARAHKDSPSEDSIITDFHRLQCRGSPDDVQIDLDVPRTISRHVMFRKRYRGGQRLLFRVLHALSLYFPNTGYVQGMASLAATLLCYFDEEKCFVMLVRMWQLRGLEKLYSPGFDGLMAALNDFQTKWLDGKDVAKKLTELCIDPTAYGTRWYLTLFNLSIPFAAQLRVWDVFLLLGENPTDSPKVPESPVTMNGIDILHSTSAALIHALRDVLLDSDFENAMKALTSWIPVKDEDILMKVTRAEWKARQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPV6</accession>
    <name>A0AAD8UPV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H2 subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribonuclease HI subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_570390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368457.1">
        <property type="nucleotide sequence ID" value="XM_060504299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPV6"/>
    <dbReference type="GeneID" id="85388198"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09270">
        <property type="entry name" value="RNase_H2-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040456">
        <property type="entry name" value="RNase_H2_suB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019024">
        <property type="entry name" value="RNase_H2_suB_wHTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041195">
        <property type="entry name" value="Rnh202_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13383:SF11">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09468">
        <property type="entry name" value="RNase_H2-Ydr279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17745">
        <property type="entry name" value="Ydr279_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rnh202 triple barrel" evidence="8">
        <location>
            <begin position="40"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Ribonuclease H2 subunit B wHTH" evidence="7">
        <location>
            <begin position="129"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="431" mass="46969" checksum="5D25E0C351ACC3E4" modified="2024-05-29" version="1">MARTRATKAAPAAKTELSNASSTAKYTLPEESSSAPQLFIIPHKATREARIVSLPNPRYSKPTRYLLCPETGIYEFTKVAAPKTTPRSWMIEIPAGTLEESDVKDESRLEAQVTNGADLFVATAVDPLFLLVPGLFGTAKPIDTKRLFLSSDDHFDAVSTSSSHMSEALRCPKTRALLESRMEVVCDTVDAGDEKMYRLSEKKLVLEILAKARSMSSKGLPASMDEKFVKKVLEAPIQVQKSQAAKVEVAANEANTSTASNESGESQSSVSTVDSKASAASNASTAATSVDGQPSEETVVSAIQASAEVTSLQRLKVAFSFICSSYVAPSMSLILKKLLNDKETSGVDFSPLDEYLVQLTKLRAEAASSRSMADYSRKRMLDEEEEEARAEKKRKMEEEKKKKASQTRGVKALSKVNTTGMKKMSDFFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQA2</accession>
    <name>A0AAD8UQA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_262314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366375.1">
        <property type="nucleotide sequence ID" value="XM_060502003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQA2"/>
    <dbReference type="GeneID" id="85385902"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="20063" checksum="92B2DA465CB03F0D" modified="2024-05-29" version="1">MQPARPLLILLHIVTYRTDTQYAVKVLYCTPHRPHLTAPHVQYFVHARYTIRDRDEEKQPAQYPVSLLIGHMPRICRPQIVTPSSLLRATRPSVTVSTLSRSREGSMVCFLSQVTLLFKTAFGDAMPRHPKPHTMRRSATRATRVSILTFNSNTILRRKRKRTEFSKVPPPHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URN4</accession>
    <name>A0AAD8URN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin fusion degradation protein UFD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_572920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367200.1">
        <property type="nucleotide sequence ID" value="XM_060504566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URN4"/>
    <dbReference type="GeneID" id="85388465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="16"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="119"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="318"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="41611" checksum="D13E260EFECE8AB9" modified="2024-05-29" version="1">MYNFARGGRRPIVQRFDEYYRCYPMVMAPGPERPDLNYGSKIFLPPSALDKVSKLHVQWPLLMEIINGEKGKHSHAGVLEFVAEEGRAYLPHWVHQMMQTLSLDVGDMIQIKTTSLELAKLVKLQPQSTNFLDISDPKAVLEKAFRNFAALTKGDVFNFEYNDEIYHVAVLEVKPETDKMGVCLIETDVEVDFAPPVGYVEPERQQRGSGTSTPRSGRGGLPAGGLLHSQGSMAQSINYGAIAPGTATTNSKFSGEGQKLSKKGSKASTPKPATPVAGASANPPALPIPRRNNNGPMPLRLPPNKLFFGYEIKPVKTDDDKKRELEEQKRPHFAGQGQTLRAKRKGEAEEKEKAPEKKGPAEGRRVDSRGPKPRGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USM0</accession>
    <name>A0AAD8USM0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_616441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366424.1">
        <property type="nucleotide sequence ID" value="XM_060507976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USM0"/>
    <dbReference type="GeneID" id="85391875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61662" checksum="5E43A50F5C6D8084" modified="2024-05-29" version="1">MCILLTRNFRCFPGGTLSWHTFQYIVRCASPRYAECLDPKALTKQSEEYDIACHECTGKFLQPFTKPKRFTESIVDENCIEAQAATEQYVKSMVEFLNMALMDAGQRLQTRFEGNVDDQFVNRVSKIEIACRFNKDHVENGPYCECLETDDATKEFDTNRITELHNNAAAMRRIVSQSYFFPWRGFWPGANTGNRLADEFNHRLLAHTRRPANDGELDPDRPSVEQHTESHRQQPGFTFLINLGDRKPHESGQITAVPVLKNALDIMDRVSVLTAQLAEKIDSFGGRDEWERSLIGFFHVPLFADFVAANFDTRMQVSNLVAHLLAHDPGLTRARIASISRIFLEFWHVDIDVMQANLPQDLGTLFVRLFKWSMVSITQRGSIGFRSGAYAGGMLTGPGHYKHTEYILLRNASLRFKDELSRQSLLESVVAPLREAELQKLDDTDCFICMEPLGTGRDPHAAVRVKCPSKNHVVGKNCWMKSHRRRSKFDPRELKCPLCSDFVLGEWKMPFNNTELWAGDLVRKTVPQLLEEMGPSGYAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUP2</accession>
    <name>A0AAD8UUP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_615655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366680.1">
        <property type="nucleotide sequence ID" value="XM_060507909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUP2"/>
    <dbReference type="GeneID" id="85391808"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="64" mass="6639" checksum="C309B51F4A46101D" modified="2024-05-29" version="1">MDHGCAFSIRPGDSIDGREFANAGCRDEGPDALDTSISIGGVSCIQLVGVADPEQPCGFNIVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV10</accession>
    <name>A0AAD8UV10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_573665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366860.1">
        <property type="nucleotide sequence ID" value="XM_060504635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV10"/>
    <dbReference type="GeneID" id="85388534"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40636:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="91" mass="8589" checksum="3C990DD5CDC6B81B" modified="2024-05-29" version="1">MPVGNSDQNAGVTGGAKFVTSALGNTVGGVTRTVGNVTGAATQGVGDTISSATGSAGRPVGDGISNLGQGLSGALNSVGKGAEDAGQWKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVI4</accession>
    <name>A0AAD8UVI4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_648727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368519.1">
        <property type="nucleotide sequence ID" value="XM_060510213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVI4"/>
    <dbReference type="GeneID" id="85394112"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019594">
        <property type="term" value="P:mannitol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF13">
        <property type="entry name" value="L-XYLULOSE REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="29726" checksum="562CA84CA12F71E4" modified="2024-05-29" version="1">MATNGSINGTKKSIRAPNPPIEDSVFKQFRLDERTVIITGGAGGIGSEIARGLAEAGANIAIWYNSSKAAVSIASTIAKEFGVKTKAYQVDVTSYPAVEAAVAEAVKDFGRLDVMIANAGIPSKAGGLDDKVEDWDRVRAVDFDGAYYCMRAAGLVFREQKRGVGIITASMSGHAANVPQEQSCYNACKAGTIHLARSLAVEWAKWGGRINSVSPGYIDTVISGDCPFEMKEEWFSLTPLRRDADPRELKGVYLYLASDASSYTTGADFIVDGGYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW56</accession>
    <name>A0AAD8UW56_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_202639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTI2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367445.1">
        <property type="nucleotide sequence ID" value="XM_060501661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW56"/>
    <dbReference type="GeneID" id="85385560"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110078">
        <property type="term" value="C:TTT Hsp90 cochaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018870">
        <property type="entry name" value="Tti2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10521">
        <property type="entry name" value="Tti2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="240" mass="26552" checksum="0C47FE27A78BBB5A" modified="2024-05-29" version="1">MLSDVVEALQRATSSSLEFNVDTDLPKRYTLTDLAQDLPEVEHLPQIPTLSALSLCLRSVDRIDQVSQDHESIAQLSNHALGLLSNSSGSLSNTNPALAEQALDVLRSLVVRFSPSLDDQDLIVIAAYTDRKRTWTTVNAELYAREILKRSLDDVRKQAFITSVVLEGFIRPIFSRTSSSRITSTGRKAHFADDSQDRFTAGSIADTDDAKPWKTTQAHAITVFSWVVEHSNVGHTSDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWD0</accession>
    <name>A0AAD8UWD0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tyrosinase</fullName>
            <ecNumber evidence="2">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_613016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367565.1">
        <property type="nucleotide sequence ID" value="XM_060507739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWD0"/>
    <dbReference type="GeneID" id="85391638"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="9">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="10">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1727510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="516" mass="57510" checksum="B49307FD7D96266D" modified="2024-05-29" version="1">MGGTITRKNIRTLSTKELDDLVKAFHGIQKLPPHDPNSFFTIAGYHGEPFRGAGYANPAWWGGYCNHGNVLFPTWHRGYLLRLEKALQSQVAGVALPYWDETEKESLEHGIPPIFLQRKYKFSDTGKEICNPLFSYTFQARIRDRLDPIQGADYTKPVGYETVRYPFSGLVGPKDKKKTWVHNNSLHEMGEEATNKMLNDNITTWLTKSSFLNSDGKRQSAGVKDKYYHCLDAPNYTVFSNTTSAQQWNDDGLQEPGFKSVTPLESPHNLIHLAVGGFDLPGSNSDQIGDANGDMGENDTAAFDPIFYFHHCFIDLMFWRWQKKHNKEHSLEIIQGYPGTNSVDNQGPTPGVAGGTWLTLDSPLDPFRNPHGADKAMTSRDVVNIADLGYAYDFPDPPTRVGEPHGPSPVLTVSGINRAAIGGSFVVSAWATLKSGEKVLVGTEAVLSRWHVSGCKNCQNHLEVRTHIPVEGWTKKDTDKMEFEIGLHTRNLSGVPKDGRGEGVQKPRFSLETDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X872</accession>
    <name>A0AAD8X872_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-ribosomal peptide synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_594349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000243">
        <property type="protein sequence ID" value="KAK1705339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357607.1">
        <property type="nucleotide sequence ID" value="XM_060506710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X872"/>
    <dbReference type="GeneID" id="85390609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="29916" checksum="6434192D5579781F" modified="2024-05-29" version="1" fragment="single">EKTHRFVGWTMLGLFWVQVVLGANDSKVANMSLGAACIRTPGFWMLAVATMSIASSWLFLKKVPVEAEVLSDHAVRLHFDYTVPVNGSFVRLSQRPLLEWHSFATIPAPEKVEHREKGFSLVVSNAGDWTKNCIQKPPTHIWVRGVPTCGVMRIATCFNRVVVIATGSGIGPLLGHIQQPSCATQLIWSTPKPEQTFGKPLLDAIKRKIPNAVIHDTKVSGRPDLVKMGYNLFQSFNAEAVIIIANEKITKKVVYGLETRGVPAYGAIWDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9B3</accession>
    <name>A0AAD8X9B3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_638943</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000152">
        <property type="protein sequence ID" value="KAK1711965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359289.1">
        <property type="nucleotide sequence ID" value="XM_060509395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9B3"/>
    <dbReference type="GeneID" id="85393294"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="36"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="288"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="367" mass="38646" checksum="1C2D50FC917EA91C" modified="2024-05-29" version="1">MASAQQVLLSPAELAYLHSTLSLTPPIRPDGRKANQFRPLTAETGILPGTNGSARICFSDGTEAIVGVKAEIEKTASPLGADVDGEETPETRKDAGKKEEVKGNNDWLEITVEIPASREDDAATVFLANMLSEALLADGEFTKKLRINNRFHWKLYLDILLISPPLSYPLPLLSLTTHLALLATRLPRLKSEGDEDPMFDDDWQASTFLYPRDGSAPVDGGSRPPITLLVIAVGGNVIFDPAREELAVAESALAVSVAEGKTAASTGGMDMDGRQLKLLSVRTVDPPSRLTAPGVPNSVNPATGLAGTPSKAPTAPAAAQGQAAEGVWRPPIGGTKVHVIEGMISKVLEKGGVADEVLEAIAAVELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9D2</accession>
    <name>A0AAD8X9D2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000167">
        <property type="protein sequence ID" value="KAK1710852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358912.1">
        <property type="nucleotide sequence ID" value="XM_060506407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9D2"/>
    <dbReference type="GeneID" id="85390306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="24155" checksum="490C03B8D5CDAB65" modified="2024-05-29" version="1" fragment="single">FGRTEFDQLLGHCGAVCDMPANFFGPELVAAYPESKVVLVERDIGSWYKSFDESIVAVAFKPVWRFLSWLRAKYVAEIGDITFTWLKYTFGAETKKEVLEKARGGYRKHYATIRRETPPDRLLNYNLKHGWEPLCAFLGKPIPDFPFPPVNDHEAYHEKLQIIIRKGVVAFASKATWVVVLGLIGVAAYYLGSREGLLASASKHRRNQQVNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA95</accession>
    <name>A0AAD8XA95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity nicotinic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_797085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358886.1">
        <property type="nucleotide sequence ID" value="XM_060515883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA95"/>
    <dbReference type="GeneID" id="85399781"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="54"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="59465" checksum="B6EEA87898C30CE1" modified="2024-05-29" version="1">MITGSMMRASIQPDEVRIDHDATAASRKQQANAAVARANVDNLRDDPEARAAAFLVLIGVMFMIKQIDQTNAANVRVLQAGESRNIMKELDMTSDQYNWVGSIYGIAYIIFEAPSNLLLKRMSPHLWQSRIFLTWGIITACQAAAQNRHELYAMRFLLGMFEAGMFPGIMAHLSSWYRTDEIGKPVTWFFAMSNLAGIIGSLLCYGISYMNGIRGISAWRWVYLLEGLATIVFSGVVFWLLPDYPKSPRSSRFLTEREQEFVEARLPENAPLTNDPDFAGKEIWAVLRTPLIWSFMLSQTLINIGGYALTWYLPTIVTNLGFVGLPRNQLLNMPPAFAAIVGLIFSAWFMSRAYIVRPAYIMILMSGMVVCFVLFFTITNRYGIYISCILGTLFYQSYFIPFWAWRSATLSGSTGTAFTLGLQSGIAQLGGVIGPQLFQSKFAYNGYKTSFAIAAATTIASFVANLWTWWLTRNTEYDVMRVRRKILKARKLGKVNFDDDIRVFEERRFYDGFKRQGGDSGEESSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAY2</accession>
    <name>A0AAD8XAY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360577.1">
        <property type="nucleotide sequence ID" value="XM_060506046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAY2"/>
    <dbReference type="GeneID" id="85389945"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47285" checksum="FBFEA87B3EF2B2F1" modified="2024-05-29" version="1">MAGIAPGRTFTPGLDFSNQSYSKLSEKVQADITRAHNIIKEKLPLLTQLNALVSLTFGDRVPIFVDARSSEAKFLDSCSDEPDTKVTIKPEYISQFYEGKLEPRYGLFKDAFFHEASMPKGNIPVAIKFADLLTPNPPVPPKKVVPGAFARLPEPTEDIDQVKRDIKEFGYGLVKNALTPEQVSILRKGTQEQAAGERKAGVSAADGGPNAPNQRIWTLINKGEEFLDLLNHPLIDEIVPWFLGEHALIHSYSANIARPGNVPMQLHTDQVAIQPPMRELAFGLNIMWYLEDITEKNGGTRVFPASHLGQIAPDDLFTIDGTVAAEGPSGTALVFDSRLWHATGPNREESGERPVILIFFMRSFIRQQENNFLSLRKDVEAKLSDRHKRLLGFYTTGALGGIEGEVREGIFVTRKDDCVGTLRAAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB29</accession>
    <name>A0AAD8XB29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000264">
        <property type="protein sequence ID" value="KAK1704419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357431.1">
        <property type="nucleotide sequence ID" value="XM_060515085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB29"/>
    <dbReference type="GeneID" id="85398983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042228374" evidence="1">
        <location>
            <begin position="19"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="100" mass="10721" checksum="B212E8E9585BE1B4" modified="2024-05-29" version="1">MKPSLFLTVFALALASEACDTYKYCHCTNQDGSANDSATTSACASGDPIIYDRGFAECKHYDNYVYVVKAINNCDFRKACNAKGAVGDSSCRAKVGIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC48</accession>
    <name>A0AAD8XC48_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_109313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000156">
        <property type="protein sequence ID" value="KAK1711630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359183.1">
        <property type="nucleotide sequence ID" value="XM_060501078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC48"/>
    <dbReference type="GeneID" id="85384977"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="462" mass="51306" checksum="3CAE02A0E3885861" modified="2024-05-29" version="1">MHLPSSAPTASSMSSPEPIHATPPTSSPIPAMPSPAKRKRRLRVFRPDEGSLYDQMWDHAGLSLFVRPICWTELHVQLLDAKFVELPPCDTPVPPPSPRGAPVSPSKCHMKPSIAASTLSRELTAMLAPGSTRTFYTNSVRTIMSTLYPGKLSRSRTQLDLHLYFGGLVYRDACRVQVAWDAVPSRSGSIASFESASTRPADSFTVVPTGSNGSASNMSGEQTGYVQSQPVLAYVGKMQIAATRKNMYRVIQGPNRSYNGPVERLQQLRSKMFVPSNPTHDPLLVGIMLAMAQRRFHGEPRPSANKWVPSRPMPTGLGEPEFHDVAIQLLTNDNETSEFIVYKATVTADLLRKFHEPTKNPRKGVEKTFAERIGEVASEGGMRIEYTRVPVWPILGLKERLGKALGKDVVGEFDEDNIETWEEEAERNPDKLKRRRDREALVEVFNGSFEEEAPADAGRWAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCD0</accession>
    <name>A0AAD8XCD0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_590022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359453.1">
        <property type="nucleotide sequence ID" value="XM_060506291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCD0"/>
    <dbReference type="GeneID" id="85390190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="301" mass="33017" checksum="E34DCD0D4A84E3B2" modified="2024-05-29" version="1">MSSIKKVAVIGATSSIGRYALPALLEANFKVTVITYSDEGKSFPPQVKIATTDFSPQSLHEVLKGQDAVLCVLGHAVFDKQIDLINAAAKAGVKRFIPSDFGTPKGPNDVPEYRAILGKKAQAQALLEERAKENDSFTWTSFWNGPLLDRVSSMALFPDFGFDLKNHSATIYDSGNEPFTAMSIGKIGKPIAAVFKRPEETKNRYVRLSALTTSQRAILEALERLTNQRWDTATVSTDEARRQGSIKLQKGDYKGAYVGFLVAQLYEDGAGRSVLDGADNELLEVEPEELDEVVRKALAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCI0</accession>
    <name>A0AAD8XCI0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_757553</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000171">
        <property type="protein sequence ID" value="KAK1710340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358810.1">
        <property type="nucleotide sequence ID" value="XM_060514912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCI0"/>
    <dbReference type="GeneID" id="85398810"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000013">
        <property type="entry name" value="Mitochondrial presequence protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000011">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="16">
        <location>
            <begin position="481"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1710340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1004" mass="111649" checksum="EA2D45850726C045" modified="2024-05-29" version="1">MLRNAVNTAKKAVTELSQYPKPGDKLHGFTLLRTKHVPELELTALHLQHDKTGADYLHIARDDSNNVFSIGFKTNPPDDTGVPHILEHTTLCGSQRYPIRDPFFKMLPRTLSNFMNAFTASDHTFYPFATTNSQDFKNLMSVYMDATLHPLLKESDYTQEGWRIGPENPQAANGEESDLVFKGVVYNEMKGQMSDAGYLFYIRFQDHIFPDINNSGGDPQKITNLTYEQLRKFHAEHYHPSNAKLFTYGDMPLSDHLQEVNAQLSAFERIQEDRTIHQPINLASGPREVTVKGPLDPLVDPDRQYKTSVSWIMGDSSDVVESFSLALLSTLLMDGYGSPLYRGLIEAGLGTDFSPNAGYDSSAKLGIFSIGLTGVQEADVPKLKAEVQRILQEVRQKGFDRTKIDGSLHQLELALKHKTANFGMSMLHRLKPKWFTGVDPFDSLAWNDTISAFETALAKGGYLESLIDKYLLNDNTLSFTMSPSTTFSEDLAREEKERLASKIKQASEEAGGDEAARKKFEQRELDLLVEQGKSNTEDLSCLPTVHVKDIPRSKEPVVVRDETANGVKIQWREAPTNGLTYFRAINSLDNLPDELRELIPLFSDSIMRLGTKDMSTEQLEDLIKLKTGGVSVGYHSTPSPTDFHQASEGLMFTGMALDRNVPVMFDILRKLVQDTDFDSPEAALRIRQLLQASADGVVNDIASSGHQYARGFAEAGLTRNAWFRQQIGGLSQVKLVTSLANRPETDGLADVIDKLKQIQKIALAGGNFRTALTCGAESTGANLNALTSFMSTLPKDLPLPSTSQPATLQKNIKSFFPLPYQVYYGSLAVPTVSYTSADGAPLQILAQLLTHKHLHHEIREKGGAYGGGAYSRGLDGLFGFYSYRDPNPQNTLSIMRNAGRWAADKAWADRDLEEAKISVFQGVDAPQSVNSEGMGRFTSGITEEMKQTRREQLLDVSKDQVREVAQKYIVDALAKEEESVAFLGEKRAWVDGTWKIHEMDIGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCI6</accession>
    <name>A0AAD8XCI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358825.1">
        <property type="nucleotide sequence ID" value="XM_060506424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCI6"/>
    <dbReference type="GeneID" id="85390323"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="627" mass="69524" checksum="8FAD42D937F54B88" modified="2024-05-29" version="1" fragment="single">IVGGGPTALASAISLAEKGAGKIQVHVYERRWIVKDRPRGPYIDYPPTARRRDQVVTLQKSVTTLMSKATRQVLFEGRPERVWPGSANIQIRKVEDRLLRRCHAAEFQDVIHLHAEGVTHEDMAKLDDFHVLLGADGAASWIRKSYFHGYENERGRSYALGLAFDRPAGLPWSQPLNVFLTLGQTRYLLNASDYDGRGYLNMQLTEEEWHKMLARDGQPVTFGYPGCLRKSDGTIPKGFTENQVFAPSEDRESSLWRSISDGLKLFGFKESEVINVVRIPIVVQAVREGIQYLPPCDSEAIKRPHALVAVAGDAAMTVHFWPGRGLNSGVKSGIALGDEIVHALNGGKFVGLPLTAMNQYNEFIMKLQDREHDKRSIPILNQSGTPETLGWLLSKANTVPDNVAIEWLVGAMAQIAERLEQRGDWAFGPVANVEPQLRIVLRQMDSATLREMAVSFPWPTREMGGAEVLPLRSMKPEEKQRWLQGIWGLLRDEVSRDSQKRPPYRGDRGRPLSTSRFEAPRGAALLPPRAFSPSPQFLSPTPNDAAPSRSESTLRRSNANRGGMSPGPSERILAVPNEPDGNPSSRPRLPSMGGEIPLGRLLSVSQRPGRAVLADAMSLVLFRVDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDQ9</accession>
    <name>A0AAD8XDQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleotide-sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_628918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362591.1">
        <property type="nucleotide sequence ID" value="XM_060508735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDQ9"/>
    <dbReference type="GeneID" id="85392634"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="437" mass="47564" checksum="D85D1BD029DB76D1" modified="2024-05-29" version="1">MHYSRIMPPVGDHRYFTSTAVFLNEVIKLSICLTCSIAEVSRTLAPSTPATVIFEQIFNSVFSGDGWKLAIPATLYTLQNTLQYVAVGNLDAVHFQVLYQLKILTTAVFSVTMLRRALGMKRWISLIILTLGVSIVSLPQPSSASHAESTSASILLHDTTDHFFPRSVHELGQAAEGAAEVARELTKRAADGLAGVGGEIVKRSASYQGIQEDQDPSPLMNYSIGLTAVLIAAVASGLAGVYFEKMLKDSGTHASVWTRNIQLSFYSLFPALAGVILIDAEDIAKHGFFDGYNWVVWTAIVFQAVGGVLASLCINYADNIAKNFAASISIVISFLFSVWFFNFEVNFSFILGTTLVLAATYIYSIPDRKGRPPPITIASYEKAMVDPAYTPAVTDETKLNLDPLDAVRSMGLSTSRPSSPMLHHHRAPSARGKNRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEW5</accession>
    <name>A0AAD8XEW5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_754556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362243.1">
        <property type="nucleotide sequence ID" value="XM_060514486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEW5"/>
    <dbReference type="GeneID" id="85398384"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF30">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="7"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="193"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="35999" checksum="11D89F2295AE4B6E" modified="2024-05-29" version="1">MTQQAKILIVGCGSVGTMCAYALQISGDAEVTAILRSNYDLVQDHGYQIHSIDHGEIDGWRPHHMERSLKDALRHGPFDFVLVTMKNLPDVYSIPDIIRPAITAQTSIVLVQNGIDIEQPLLEVFPNNILLSGVPLIGCELNGREMLHNDPDILHIAYWPNPKFTPEDQSNACTAFAQIYNNGGAKCNIQTDISWFRWRKLIWNASFNTVCAITNLDSGVVQDAGGLDTLIRPAMKDIVAVARAAGHMFSDEILDDMVAFTPKEARLKPSMQVDAIRQKPMEIEVILGNPIKTAKKLDEPVPTLEFLYSVLHTKQWGFLNLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF35</accession>
    <name>A0AAD8XF35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_624446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364076.1">
        <property type="nucleotide sequence ID" value="XM_060508443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF35"/>
    <dbReference type="GeneID" id="85392342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="497"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="861"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1035" mass="116509" checksum="46508B6D4BE4A653" modified="2024-05-29" version="1">MVINYTLSSSPPPVGSSAMGTSPIRDIRRGNDADELADETIPESPYQTQATQIVNRTSLASQAKPQPDTSSSPSSRSVIEVPASSPFQNKSSYFSRLVPPGSRFQPPPKSQAPSNPRKRPSAEPVLIQGSSDDEDDRTSRGNISQTSFKKHVANFEYVSVDKLQKKIEEVSEALNGTIPVQYYKEALTACHNNVEDAINYLLDGRHLKPKVNSFVSSTKPSNTVGDERTKTVDRKSGRPGSPSKPKLLGRHAPTLPTPSRSTTPSPPKPKRRRLMQGRRPGRSPPASQQPHEDEPSLDELAADKVDEPIIIPDDNEDEDFDNEDELNEAVKDSLQDKALQAINTSSIADLSAMTNIKMDELKIIETKRPFDTISEVQAVSVAKKANARSRRPKVPIGETLVDAIMEFTRSVNAIDEVVAECEKKANKVKQEISRWDLDVKGQKRSTQSSSTNSDLPLTPTSFHAQKLSEPPISCQPKFMDGHCTMRPFQLFGLNWMSLLYNSGYGCILADEMGLGKTCQVISLICHLVENYEKTGKGERPWPNLVVVPPSTFSNWMGEFQRFAPDLSILAYQGPQAERREIAYEMLENPADYHVVLTTYTQVGSEEDLEALRELQPAAAIFDEGHKMKNPKTKIYKDLIRIKAGWRMLLTGTPVQNNLMEMLALLNFIDPLQFNGRMDQLQYMFSQKVTIRDVNNGAFLYGERVSRARTILEPFILQRRKQQVLSDMPAKICNVAYCDLAPGVQKELYEDYERLFKAGPVKKTTTGRQSDQNNSWMQLRKAALHPQLFRRYFDNKKVEKMANILMQEVPQSELQQPRIDHLIGELQNSSDFELHLWCRDYACIRHLDVPEGSWMDSGKVVKLLELIHQYRDNGDRVLVFSKFAKVIEILREVLHTDNIRHCVLYGQTNVAERQDLIDEFNNDTDITAFLLTTGAGGTGINLTSANKIIIFDQSDNPQDDIQAENRAHRLGQTRDVEVIRLLTSHTIEELIYKACQKKIELAEKVTGAVEDLDDKNAEENLEKEVRKMMADQLTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFE7</accession>
    <name>A0AAD8XFE7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_785867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361555.1">
        <property type="nucleotide sequence ID" value="XM_060515640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFE7"/>
    <dbReference type="GeneID" id="85399538"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="91"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="42869" checksum="05D59B90FDF33C2B" modified="2024-05-29" version="1">MGVAGNAESDKPVYQQAPSMLNRIVYGTKISTLQHWYFQKAGFEAWKSYFWPPAIRPDLIKQYDCRKALPVRIFFPSDYDQTSPQTLPTLFTIHGGGFSIGVPDDDDEWNRTFSDLNNCLVVALHYWKAPWAPWPHALHDLEALYLAIVDDESLPIDKSRIAMGGFSAGGNLTLCLSQMKSIKEHRTAAPKAIVPIYPPTDFVTPTASKRDRRPYKVGKLPGIRGQKKDFVLDFAEVFDWSYIPYGTNLCDTRISPLYAERGDFPDNVCVVAAELDYLAYEAWELACKLGGKGKPTSGMVGRNEVAKTQELVEDGDERFGWEARDGRGSVKWLLVPDVIHAFDFHEMGAAVSDPVSVRDGNAKAVKVMRVVGDWLRRTAWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFQ5</accession>
    <name>A0AAD8XFQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_617258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366189.1">
        <property type="nucleotide sequence ID" value="XM_060508019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFQ5"/>
    <dbReference type="GeneID" id="85391918"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF19">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="737" mass="82362" checksum="C1BDA4D3E7F8E877" modified="2024-05-29" version="1">MDELGQDHRDELGDHSHQGRRANQRRNRNAPVPESTSQHRTACFTCRAARQKCDRRTPCSRCVIQGHTCRYPLKSNRGRKEGSTNKPDTVQKLLDRINESPVRDQVIVAIINSSKAQSHSELSALDSFSSLRDSVPAQLDAAVVDETIFPALIEQSEESECDGPPDSTLSPCPCSKLKKESSVVSPLHIMAAAFTTKDTSFANQNVDTAMPYLPLDAVGRRGNEGSMRKRLIEYFTPRVTHDTDWYVLASQSINSTLKLETTACDPVTARLADQDDVSLYFQLFFQTRNPHLGLLDPDLHTPKYVRHASFTLFSVICALGCAISTRPRDRILYPTLLSLAEANLAWSIAVPVRSLETIQAILAMKYWAPMYQKQGDDPHWLHISHAVQLAKELGINKPTIIADLVKALAPDNTVEMRERFSRNLERTWLYVFIADKSFGIVMGRSPIVAWKELPPCPCQWWKKSMTTPLDRMISGIIEIRVQLLESLKQLERMKKTSVSISIWHAKNYDVLDRTCKIRCYENDASSTPTLPILAFYMKHSLMILNAQAARELRRLGGATASTIVAVNSKAFETARQLLDLALHDQTVLDIGLGWHNNQFVMVAHAITEIVQALSRGDISSVDHETAASQIRAISTWLEEKAQALPATSIASLYSAFSRLLVSGLGGEASNDTQRRQDHTSDETPDSLMTDWSRAVDVASLNPMDWLDMSFLGNEDSFGGLENVDFNDLNDNGALRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH32</accession>
    <name>A0AAD8XH32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase II transcription factor SIII subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_622432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364628.1">
        <property type="nucleotide sequence ID" value="XM_060508330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH32"/>
    <dbReference type="GeneID" id="85392229"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070449">
        <property type="term" value="C:elongin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051870">
        <property type="entry name" value="Elongin-A_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010684">
        <property type="entry name" value="RNA_pol_II_trans_fac_SIII_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141:SF76">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06881">
        <property type="entry name" value="Elongin_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="204"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="309"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="415" mass="46051" checksum="572F822BD6A351E6" modified="2024-05-29" version="1">MAPTKSLAELCIAMCQRHITELSSVGNGDALQYHHVREILLRVTNPAQLREIELNSPFIQGETSELWLRLIKKEFPSESHEKNYAPKNPSKWYKIYERYAEERREAQQQAEAELLARVQGLQQKKDNNVSRIVDPKFARFLPKPPKTGRTFSTQPRGKRELPSSLSWAAGSRMKMTTGASVMKKARREAKEIVGIRSTMAVPTGMIRAPRLKQAPPSMAAEHRISSQPVFRPTSTSSRPPTHSTYVTPQSKATYVSDSSDGEDDDLFSDEGTPKKNKGAASSSRHSRDTAASSRPTNPAQSSAFKDRNSSTSARPASSSQPSGLRRGGGILGNAARPKSNIRVERPPTKPEPSSSTSMDQFRTHKVLAQNNGPQSPPLPASLDEAQQARPILGNQELPRKRKAVDIFMPKKRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHI7</accession>
    <name>A0AAD8XHI7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_387230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363610.1">
        <property type="nucleotide sequence ID" value="XM_060502753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHI7"/>
    <dbReference type="GeneID" id="85386652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="25139" checksum="11FE4B631F4FE901" modified="2024-05-29" version="1">MVNKYSITVQNQSGSQQQYVLFNKPPMVSGRVQGQIWSNVFAHGNTPRGSRATFSVFSQYYAIVATSQGSPSTGVEIDVTSERDVILGSLKDDGTAVPGTTLQLIVAKDAPQFSDTPLPNSSFSNAFEIQTGNDFTVAQAKQGNYLIGLGGSRTGNSQDGPLATFVPEPRVRYQIQPSNTYYLTVGNYNKGEIIDVSRIGGSIATIDFTRLRSNNVVIVHDDHGRLNIQAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHJ9</accession>
    <name>A0AAD8XHJ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_544287</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366641.1">
        <property type="nucleotide sequence ID" value="XM_060503434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHJ9"/>
    <dbReference type="GeneID" id="85387333"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF153">
        <property type="entry name" value="AFLATOXIN EFFLUX PUMP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="54"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="57569" checksum="D33954CE15011710" modified="2024-05-29" version="1" fragment="single">GAIPATTPASEPPASSRTSKIHDEEEQQPAQHALTHTSTTRSIQYPKGVKLFLIMLSILVSMFLVALDRLIIATAIPQITDDFHSVTDIGWYGSAYLLTTCAFQLLFGKLYAFFPIKRVFLCSVVLFEVGSAVCGAAPDSAAFIVGRAIAGIGGAGIFAGTIVVMVHSVPLHRRPKYQGAFGAVFGIASVIGPLLGGAFTTKVTWRWCFYINLPLGGVALVVIAFVMRPPEQDLTESSLWDKLKQLDFAGTSVFIPGVVCLLLALQWGGVEYAWSNGRIIALLVLAVVLLLSFIAIQILLPNTATVPPRIIRQRSIAFAAWAAFSLGGQMMLMAYYLPIWLQAIKGFTAVESGVRTLPMVLSMTVFAAVSGGVITKIGYYTPVMLVGICIMSVGAGMMTTLEVDTSTAKWAAYQVIYGIGQGMTFQAPNLAAQTVLKLKDVPVGASIMFFSQTLGGAVFISVGQTVLNNELVKRIKGLPGLEGINLQTTGATSLTDLPDNVRGPVLEAYNGALKVVFVVALVMVCSVFIGAGGMEWKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHZ8</accession>
    <name>A0AAD8XHZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_749494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368002.1">
        <property type="nucleotide sequence ID" value="XM_060513774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHZ8"/>
    <dbReference type="GeneID" id="85397672"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042136219" evidence="2">
        <location>
            <begin position="20"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="431" mass="47514" checksum="DE188F31B86F3D9B" modified="2024-05-29" version="1">MVAPKALLAATGTLALASASSFTTITTSTTEPATAAATITAPVAPPMPHGSGPTEAMIARRRAWCKEFNAEKRRAPGWYESPDEYAGAIGYCVRFYLDEYKLNPSKAGWIEESMDRTLGRKKFLVADFEKKASPAPTATPTANAAAAASKKEDPVSEDEVRVNTAKMADILKESLGLTDEQLVELGFKLGESGFALVHAPEEDSEASSSLLWPPKFGRPARPLMPHPFRKHLGKEPTAKGPGATQPKGKEPAVEKPKVEQPKVEKPKVEYQKPKVEDEQPAAKEPKGKEIAVEQPAAKEPKGKEPAVEQPAAKEPKGKEPAGEQPKVEQPKVEQPKADQPKADEPKAKDTKSKKSKEEEEMPHHDHPHGGHHAHPHHDEHDKEKEEEEKKKKEKEMEMEKHPYHPDHPHFEEEPVEDHPTPNPPKILPDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI57</accession>
    <name>A0AAD8XI57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ABC multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_749443</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368212.1">
        <property type="nucleotide sequence ID" value="XM_060513764.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397662"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="341"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="786"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="832"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="903"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="933"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1009"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="70"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="403"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="790"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1142"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="688"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="732"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="695"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1100"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1114"/>
            <end position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1728157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1386" mass="148761" checksum="021859521215033B" modified="2024-05-29" version="1">MPDQDSRSAAAEKADTALSTSPEQQQVQTTSTETTEVAKPKGKRFETVFSFFKLLFYANPTWLDYTLVCVGTIAAIGSGVPFPLMGILFGQLIDDMNGATCADGIGDVGAYQDAVNDKVIKLVWITCVAFCLIYTHTTCWGIISQRLASRLREKYFQSLLRQDVGFFESRQAGEVSSRLNSDIQTIQSGTSEKVSHFIGTISFFVTAYVIGFIKYAPLAGMLVSLIPAYLLASMICGSYIQKWSGAMSEGMAKASSIASEALSHVAVVQAFGAGPRLENKFAGHVMVAQKEGIKKAIAAASNAGLLYFIAYAANALAYWQGSKAISRSVAGTGDGTSVGDIYTVVFLIVDACIMLGTIAPLLPLFGSAAAAFVKLREDIDKHSTIDSVTEDGDRLPTNVHGEVELRGVTFSYPSRPDTDVLKNISLVCPGGKYTAIVGLSGSGKSTIAGLATRIYDPKEGKVLIDGQDIRNLNVRNVRSYISLVQQEPSLLDRSVIENIALGLVNSPKEEHQRLKETLYGPQLAQLAEDLMAGEDLNTAAQKYGPEVVEIVKLVQNATDLADATSFIDRLKHGFGTAVGSGGKLVSGGQRQRVALARALIRDPKILILDEATAALDSASEARIQKAVENVSKGRTLISIAHRLSTIKNADNIIVMSAGDIMEQGTHADLIARNGAYANLVNLQNINGSEEEKAPSRASTAVESSAASVDAETPGVDPKDLARAIETEAGPEAVVTEKTKKQLKKEAKELKKKKKNAALETENSGLDNDRSTWWITKKAGVMVRPHILYLLLAMVSAFIVGCTFSASGTIFGFAIGVASPCNEPSYIQSRGAFFAGLFFMLACVELVANLCSWSAFGYIAEKLLYKIRVGSFRALFQQELEWHQSGARNPSSLLSLITKDAASIGGFSGSIMGTIFAVVVNLFVAIIYSHILNWRIAIVCLVIVPMLLGSGIMQIRVLSRFEEKHAVAYATAVGITVESVNSIKTVATLSLEHEVFGQYKRALKDPKKEIISAVTFANVWLAVANVTGNIIYAFAYWWGSKQIVAGNATQTQFLIINVAMLVGAQLWGQMFTLAPEVTRARMAASRIFSLLDLSKSDADPAGKAADAADAASESSKGKEKEKDVEALANPNPRPSPGRGGVAVSFKNVSFSYPARPEVQILDNMSFTIQPGQFCGLVGPSGAGKSTVMAIVQRMYSASTGTIEIDGMDISKFDGTDFRDDIAVVPQDSALFDGSVKFNVGLGARPGQDATDEEIEEACRLANIHETIVALPQGYDTECGPNGSQLSGGQRQRVAIARALVRKPRLLLLDESTSALDAESEKALQEGLERAARGITVIAIAHRLHTVRKADVIFVVEAGAVAAKGRHEELMEKSESYRLNAMQQMLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI89</accession>
    <name>A0AAD8XI89_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Aminomethyltransferase</fullName>
            <ecNumber evidence="4 12">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 12">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_751389</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="4 12"/>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365798.1">
        <property type="nucleotide sequence ID" value="XM_060514043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI89"/>
    <dbReference type="GeneID" id="85397941"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000001">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1250.10:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="14">
        <location>
            <begin position="80"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="15">
        <location>
            <begin position="389"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1725743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="51371" checksum="29D385C6566443BC" modified="2024-05-29" version="1">MTRSRLVAAARTARPFLASPARQGRSLASVAGLSSTGPAPRTAGASQLHNSNSRFYSSASSRANWKEKLAAFSKQDKTPLYDFHVAHGGKMVIFGGHHMPVQYAGQSLAESHHFTRTHASLFDVSHMVQHRFTGPKAAAFLETVTPSSVADMELNTSKLSTFLHPGTGGIVDDTMITRLGEHEYAVVSNAGTREKIFAYLTEHTAALQNPEGTDFWWEVLEGYGLVALQGPQSAEILQEVLDPADGLDLSSLYFGNTGFARLRYQDSQGQWQSTPEKAMISRGGYTGEDGFEISFKSTNGEAGPIAETLLKVAGPERLQLAGLGPRDSLRLEAGMCLYGHDIDDTTTPVEGSLSWIIPKERRSKGGFHGAEVINKQLVSKSKGGAGIERRRVGFVISGAPAREGAEIFTKDGEKVGVITSGSPSPTLGKNIAMGYVKEGLHKSGTELDVVVRGKKRGAVVSKMPLVPSKYFKGPMPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIA2</accession>
    <name>A0AAD8XIA2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_612737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367481.1">
        <property type="nucleotide sequence ID" value="XM_060507728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIA2"/>
    <dbReference type="GeneID" id="85391627"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="22030" checksum="9D0A4C3BD9F5CC2F" modified="2024-05-29" version="1">MGKSQSKLSQEQLAELQKSTHFDKKELQQWYKGFLKDCPSGMLTKEEFQKIYRQFFPFGDPSSFADYVFNVFDSDKSGSIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKISYDEMLKIVEAIYKMVGSMVKLPEDEDTPEKRVRKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIB3</accession>
    <name>A0AAD8XIB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_610008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368422.1">
        <property type="nucleotide sequence ID" value="XM_060507573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIB3"/>
    <dbReference type="GeneID" id="85391472"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="294" mass="32323" checksum="963DEFE18D76E532" modified="2024-05-29" version="1">MFKNSEILRAREQQEEDRKRLKEEVDLRGKQGQDTTKGEQVWYSRRVDDGCLLHWAIITHGQKHELRLPNGSVPKPRDKVPESEKTSSFEPARVYEARVVASSLKEEMNKLRALKLSTPAKGYHTRDYTVCQIGWTTLTKDEVNTEWAAARSSIAAEDLGYDDCRELLKKFGGIIKKPEGCALDYDWFTESLETPTHKLTEITPDKAVKGFQNSMQNGLWGVAASGVGAGIVYGAYEAGKQMDPLRSGANAGGSLGPDCCCAGCYCCTGMAGDGSCWEFCTHAPCMALSGGCTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ03</accession>
    <name>A0AAD8XJ03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_569979</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368681.1">
        <property type="nucleotide sequence ID" value="XM_060504254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ03"/>
    <dbReference type="GeneID" id="85388153"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="38820" checksum="1B316E13EAAB9674" modified="2024-05-29" version="1">MQHSGSLGENSPLTLKHASFEDEITSSSTKSSSSSWSSTFTEVLRIPRLIWDFTESNFATFVVPNTAFGLLGGLTGAPLTSGHASTLSIVQRFPLVVAFNWYSVLIFDLANQRGPESVAEDLANKPWRPIPAGKVTPEQTRKAMLVAIPAVLALNYVLDVWNEGVFILILTWLYNDLRGGDELVRDAIIAVAYFLFNTASLKIAISGGAATGTAAAGAADDVRVPITITHEGYAWAGIISAAILTTMQVQDLKDQAGDRGRGRATVPLYFGDRVSRTSLAVLVPFWSCVCVYVWHIRSSWAVLLPTLSGAMVVAAVLRTRTPETDARAWKLWCLWTVCLYSLPLVGDGFVSLASQHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ89</accession>
    <name>A0AAD8XJ89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fermentation associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_750018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367523.1">
        <property type="nucleotide sequence ID" value="XM_060513861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85397759"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006113">
        <property type="term" value="P:fermentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029636">
        <property type="entry name" value="Csf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056779">
        <property type="entry name" value="Csf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048636">
        <property type="entry name" value="Csf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32085:SF3">
        <property type="entry name" value="PROTEIN CSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25038">
        <property type="entry name" value="Csf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21678">
        <property type="entry name" value="Csf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="Csf1 C-terminal region" evidence="4">
        <location>
            <begin position="2495"/>
            <end position="3244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1160"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1762"/>
            <end position="1782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2464"/>
            <end position="2492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3143"/>
            <end position="3170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1766"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="3149"/>
            <end position="3163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="3245" mass="359074" checksum="F840251A05A94ECB" modified="2024-05-29" version="1">MPQEGEPNPTPTETPAFRWEFLVYLIICGALAVFFLLYFNRAFGSLLSWGIRTYTWHRYRLYIDIQALQVSLLGGRIFFTGLRYHGNNETFLIQHGYVTWRYWLRRVREVDIKASAQQQAEQASAGTNGRHSNLPCRVTMSLVGLEWFIYNRSPAYDSVLAGLKEPTATAENVSTAFESKDENASLRNRGQRTTEKPEPSPDSAEHEKETSGAALLSRIGNTFGRRGSSASQTSTHSDGPAGSSDDVQADSDLPFLLQLFPIFVTCQKAAVVMGNDNTKAILIVKADGLSGEIDASKTSTPDPYRQNFKIKFQHPIVEMRENDDFKEDQATRASREKQAAQEPSPTYKTSFFRRQKRRTLGTLRNLVPYWRKSVESFSLGSRSPLTTAVSQIPGSNQWQGLARYLDEDEQDSRLRWAGVEYAAESTVVDSPEATLTIYWDVVGKVTAEAASRRSKENAATYINGDEAPGWGMSLAINGGVVNYGPWADRHRADLQRVFVPSLSKDAVPATPLEEGAYRVPTQFKLFVELLDEVTLRIPIREDSKNWKWKGKEPPMKAPPQPMKRKQRNRAKKNMKTDAAPTRPGGWLDFIVPGNSTISFTMDMLASQTGYQMKLDVDLPSTELATSVNHELLWRSGLQRISCDLSTPLKWNTLRTWYFNIVTEQMELFILRDHVFLIIDLVDDWASGPPAEYLVFTPFRYYLNLELRDAMLYLNANDGNIINNPTDLEDNAYVVAKSPSLIVNSCIPIDKFRPSMNTIPFVLSAETFSLWLHVPPWNTQGTFLTSKEIGHGENFEVDGKYHYNATTSPANIDTLEINLSLQSPTATIYGFIIRYVLVLKDNYLGDYIHFKTLEEYQDLLRLKESNPDAELANRPPPKKSNDLDVILSVKIDDLRLLLPANLYSSQRNVQVETAGLSLDLRFTNYYMDLQVNLNPLNLSLGNAESGSETPISAVSSTQLFIDGLTIYGHRLFGLPPSEPTYMCNWDISVGTVSGECSADFLTALMGVGKGFAFEFDDDENALIPLSSVIVYDVTFLRVAVEAVRVWCHVDEAAFLFSTGTLDIKFNDWARTHYSRRADIRLPDLQVSCVNSESAMRHKWKSQHGVETDAFFQASIRVAIIGRKFHFSEERKLQQELIRREDQRAGRTEFLLLPGILEETLPDQLDPPAQGFPPVPHPTVLDGVEGDQRSFDSRSAFSRSRPLRHKSSFLSTSTASSTSSVVRPRSSVRSRAKSRQSDLLHPDGSEAKRGGQHQRDVSTSTGRHSAFYSAIGDVRDASHHSSVAFSSQFYTPPFPLESVRPDTSEAVMQSIEEDEEASAFGFSEFGLGDIDPESLTEDRAHNSIILEIPSGVTAFLNPSAVKNVSLLLAALQPSDPDDILDTLQTSSMTDIFDLQKKRKVAGEITDVLVRVPKASIRFLNSSTVDRMNPGGEEQDQYDVTVSKLSLCLRSTDAWKDPLKPVESNKRTSVLLKLGSAEVSASERLSGAEENQAAFMAQIESVMVSLGSKDVTYIDADIGSIKSSTASEKIEYLASLIHRTGVVAAELGEVLGQTMSRHEDRIKHFVYKLMTEGHPIGDPSFLTRPSAVLRSAEEHLRTFDSWKMAARLRQVWTHLPAAFKEDLHLSCLAASASPPADAAQRVIDAFQRWRSWDLSDVADSSLIKNVFGAVKADGRPASPDLPILAALRLKDVQLLLDPGPKENRVVFSDLTTRLEQKAVPSADGAANVPKNMTVLNVYCGEAAVILNWELCELAEDVLRLYNKSSRATKSQEPKSEPKVDDPAKPKTQNAFHVVLAVGRGSVEVDTINLSATSLGHNMKVSCLVDAYEKTGSSINFILSCDAVTSRLHHRSELLGMFQIKDPSIIVSHELLETDTTSCHTIKSTASSRTLTFAVKQDPLYLVEVADYLVKDELTQIHKLQKQLPESPAPPRRNSVKIAERLSSFRVNVAMFLDEYRISVPLLQSMTYNISGVVARAAVAANFGKELIFDFDVKENSHEVRMDVRDRQRSISLLRIPPTNGRIVSHMGQGEHSVSVFGSVELMQLDASAVYSLLTALNRPQISSAVSELQEGTKAIQGHISEIFGEKAIPKEKPSPPEPDSSFIYTIHLTLAGIEVFGNTPLVSERDPTACLSFKLDRVHLEVANRHGSHGPILAQPELHINLRQILIDVQKGRDNAMRSCGSLALGALISMNTRCTEDGTEERSFNFRSDGLEIELSPETVSTVVAALGYMGDKIKDLDTSRELEYLRKIRQTRPRIAINDQEEAEEPDIIDSFLSSIVYRFEVRDTQISWLVGDPSDELLPLAGSKEDLIMSVQLVSFGTRQTKSARLSIENFQLQMVPPGQDKSLRSLHSALLPEVVFNIAYVSNPNTRSLAFQAVGKSLDLRLTSGFIIPAAILKDSISLSMQNVQRASQNWTTGTAPPKVDKVDEIKEPAPPQRSILGTKRLESLLVDADFSGAVVYVSGKKPTDGLRGSSRTGRPSLAGKYGQFSTDDTGSSTVLRSPGLAWKFEYRDNGNEDPSLYGEIKIDASSNILYPSVVPLIMDMTTSVKEVVGKDKDMPASAAAQTPAAAAVKPKTGNEDNILTADPNAVIGRLKLNLGLRICRQEFSLSCQPIARVAATTCFDDIYFTVNTVRSQEQGNFFSISGAFSKLQASVQHVYSRESTGSFDVDSIVLSLMNSKHVSGTSGVSAILKVSPMTVSINAKQLQDFLLFREIWYPTELRNTTTAPVAKLNTETSQQGHLVQRYQQVAATAAFPWTATISITSLDVSVDMGQAIGKSVFAIKEFWVSSKKTSDWEQNLCLGFEKIGIDCTGRLSGFIALQKFQLRTSIQWPEREAALNETPLVQASIGFSQFRVKAAFDYQAFLVADITSLELLMYNVRRSLEGTGDRLVAIFDGDAVQIFGTTTSAAQAVSLYQAFQKLIQERRANFEMSLQEIEKFMRRRSYQSAALSPHLTSAPKLPAEDTLSKAPISLDTDVVVTLKALNLGVFPSTFSDHQVFKMEALGAEARFAASIEQRRVHSILALTLGQLRIGLAGVRNIEAPKTLSEISVEDVVERATGSRGGTILKVPKVGAVMQTWQTPNRNRIDYIFKSAFEGKVEVGWNYSRISYIRGMWASHAKSLEQTWGKELPLTAALTAIKVTGVPDADTEGGGGGGEGQAGGGASQQQQKITAEVNVPQSKYDYVALEPPIIETPQLRDMGEATPPLEWIGLHRDRLPNLTHQIVIVALLELAGEVEDAYSKILGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJS8</accession>
    <name>A0AAD8XJS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactonase, 7-bladed beta-propeller-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_717759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367510.1">
        <property type="nucleotide sequence ID" value="XM_060511985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJS8"/>
    <dbReference type="GeneID" id="85395883"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042220744" evidence="2">
        <location>
            <begin position="23"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="400" mass="41332" checksum="A80528FF89E85FE1" modified="2024-05-29" version="1">MLRDLFAPAGLVPLLLSSPAAATLLYASSYSGAITTLNLTLSGTNATQSTLRSLSSSNGCAPSPSWLQLDKANARLFCTDEGLTTNVGTVSSFKTDADGVLEQLAKTETISGPVSAVVFGEKGQGLAIAQYGGSSVSWFDISSPAALTAVKSETFNMSAPGPNPSRQDAPHPHEVFLDPKGQFVLVPDLGADLVRVFAVDGANNLAAVDPLVAAPGSGPRHVEFLVTPEGKTYLYLISELANTVTAYDVTYRENKTLGFTEVFSGSTYGAGASAPAGASAAEIWISSDGKFLTVSSRNDSAFSISNPDTPGEGAQIPSDSLNTFTIDAKTGGLTLLQKFPAGGRIPRQFSVSKAGDLVAVGLQSDSRVVVISRDAALGKLGEILTSAKVDGEVTAVIFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJS9</accession>
    <name>A0AAD8XJS9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Family 92 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_770882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367525.1">
        <property type="nucleotide sequence ID" value="XM_060515353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJS9"/>
    <dbReference type="GeneID" id="85399251"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.10:FF:000028">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein (AFU_orthologue AFUA_5G10520)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2080.10:FF:000001">
        <property type="entry name" value="Alpha-1,2-mannosidase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.60:FF:000002">
        <property type="entry name" value="Glycosyl hydrolase family 92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF44">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 92 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042123541" evidence="2">
        <location>
            <begin position="17"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="4">
        <location>
            <begin position="29"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="3">
        <location>
            <begin position="281"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="806" mass="88289" checksum="673030035A2DC975" modified="2024-05-29" version="1">MRQTTLFHLTFTVVAAQSADLASHVLTDTGSVEGGNTFPGVSRPLGMVKLGPDLENGVDAYSGYLPAGNFTGFSMLHESGTGGAPKYGVVNQMPVVGVLDNPLRVNQSTDTRARPDETELGYYRAFLGSGVVVELGASERAGMYVYTFPGNNGSGTSNNIIADVSHVLPSYRGQGLGQNYLGGGIEVFDTSDGFHYEGHGYYDNGWNRAAEWKVFFCGHFDQHPSSFKTFLGTDLTSDVLSAYGNETTSYESRTQRLGAVFTFADSAITSRVGVSFISTAQACRNVDAEIPAGTSLSTVRTATREAWTTEVLSKVTTTETNATKLDQLYTALYFMNLLPTNKTGENPLWESSEPYYDDIFTFWDTFRCTTSLLQILQPRAHEEFIRSTIDIWRFTGYASDARSSFFNGAVQGGSNADNVLADAYVKGVRGDVDWTDGLAAMLTNGETPPPPNNDPRDPSSSTKEGRGALPDWLDLGFISPNYARAVTRAVEYAVNDFAISQVARGLGQDDTADTYLRRSRNWRNHWNENMTAHGFNGFLGPRNADGSFPLPAQNPLDCGGCYWAEAYYQATPWEYTFNAHHDAAHLIDLAGGPELYAARLEKTFEPGGYAGNAAFGNTIFNPGNEPSFGTPYLFNFVNKQHLAVRHARFVAKSYYKPTPDGLPGNSDAGAMESWLLWNMIGLYPLTGQTTFLIGSPWFSDLTIALGGGRELKITSTGGSEDVYYVQSLRVNGQAWNKTWVTWDDIFAGGGTLEFELGPEPVEWATGELPPSPASVVDSRKEKVAALRQQRQRRRRQEERDEQEVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKI5</accession>
    <name>A0AAD8XKI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dak1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_764015</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369084.1">
        <property type="nucleotide sequence ID" value="XM_060515228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKI5"/>
    <dbReference type="GeneID" id="85399126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF1">
        <property type="entry name" value="YALI0F01606P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="15">
        <location>
            <begin position="11"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="14">
        <location>
            <begin position="390"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="11">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="56"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1729029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="593" mass="62498" checksum="ECEBB0974056FE6F" modified="2024-05-29" version="1">MATKHYFPDTAANTLVPRALRALVSANPHLTLSEAERVVADSHNDRSTVSIIGGGGSGHEPAWSGFVGEGLLSAVACGDIFASPSTKQVLEAMRLAPSNAGTILLITNYTGDRLHFGLAAERAKASGLSDKVVVLPATDDVSIGRSKSSRVGRRGMPGHIFTMKILGAAAAEKYSFDQCVEIGRAVNDQTVSLGSALDHCHVPGRQHQSVGEDVCVVGAGIHNEPGQQLITPFPSVTDLVDRMLKLLCDPNDTERAFVSFEKGDEATLLINNYGGLSVLELGALTNEVQTQLASTWSITPVRTQVGTFETSLNAPGFSISLCNISAAARQLKSTANELLQLLDRPTSAVHWPNTVRPVTGEEKTNGLTTDKASVTNGHEQRSDLIKVNPNLLENAIRSACERAIAAEPNLTKWDMVMGDGDCGEAVKGLCESLLRNLDNGSAASGSVFAFLESTIEAVDDMGGTLGAILGILLSAFSSSLRSEAQANPASTTSFSPMLYASSLASAVESLKSHTPAREGDRTVMDVLLPFSDAFVKSGDFGAAVKVAAEKAEATRYLKARFGRATYVGDAAGQELPDPGAWALYELLLGMAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL55</accession>
    <name>A0AAD8XL55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HIT zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_789021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369388.1">
        <property type="nucleotide sequence ID" value="XM_060515691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL55"/>
    <dbReference type="GeneID" id="85399589"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="291" mass="31895" checksum="6E71ED0AF52961CA" modified="2024-05-29" version="1">MNNFGVYELASSKVTNAPGWAYVPDTGLNPAAAALQPANRKRAARSKANPTASDLTVRQEAKIRKELEQLDRDGGRDASIPIPAKASRGQNKSTPAIRKILQSQKTFHNHCDDHLALLSHAGNTPAPHPNQHTAKPANKPPHPNQHTKRNAAKRSKTSTPKTPAEPEDVEMTPAPSAEAPEDSASAAGPVLTPYDKPGPAPHPGDDNPLLVSRVPAMPTDEELKWLLSRPMLSFWDARAEWGDDDTRYPERSFCEVCGYWGRVKCMKCGTRVCALDCLETHREECFTRYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLJ2</accession>
    <name>A0AAD8XLJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_748309</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit APL3 and beta-type subunit APL1), a medium chain (mu-type subunit APM4) and a small adaptin (sigma-type subunit APS2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369622.1">
        <property type="nucleotide sequence ID" value="XM_060513595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLJ2"/>
    <dbReference type="GeneID" id="85397493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14833">
        <property type="entry name" value="AP2_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000011">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027156">
        <property type="entry name" value="APS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0168">Coated pit</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00062168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16876" checksum="A03CD89D8518B6C4" modified="2024-05-29" version="1">MLSFILIQNRQGKTRLAKWYAPYSDDEKIKMKGEVHRLVAPRDQKYQSNFVEFRNNKIVYRRYAGLFFCACVDTNDNELAFLEAIHFFVEVLDAFFGNVCELDLVFNFYKVYAILDEVFLAGEIEETSKQVVLTRLEHLDKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM33</accession>
    <name>A0AAD8XM33_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">DNA polymerase</fullName>
            <ecNumber evidence="22">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">BDZ83DRAFT_446943</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21 22">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 22">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="22"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369916.1">
        <property type="nucleotide sequence ID" value="XM_060503144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM33"/>
    <dbReference type="GeneID" id="85387043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000009">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 22" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 22" id="KW-0235">DNA replication</keyword>
    <keyword evidence="18 22" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15 22" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="14" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16 22" id="KW-0408">Iron</keyword>
    <keyword evidence="17 22" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 22" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="20 22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 22" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 22" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="25">
        <location>
            <begin position="238"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="24">
        <location>
            <begin position="535"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="26">
        <location>
            <begin position="1004"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAK1729861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1103" mass="124643" checksum="7F7689CF89C14D7A" modified="2024-05-29" version="1">MATVLPQKRVLGETPSTRRNIPSTPSSLKKRKVEGFSSSPARHVGSQKNAKNIPGSSQPKSAFESEVLEKLSQDISELKQNNTEKDQAWERPPLVDFNPARDNLIFQQIEAEEGSLHGGRATVKLFGVTEQGHSVMLHVTDFKHYLYVAAPVAFRPEDCNAFKAYLESQVAQHQPCIHSVSFLMRENIYGFQGNVKSPYLKVTVMDPKFIARVRTTIESGNANWKGLWKGMDGGIMTFDNIQYVLRFMVDCKIFGMSWVEAPASKYQVLHQSQRQSNCQIEAEINYLDLIAHKPVGEWSKMAPLRIMSFDIECAGRKGIFPEATHDPVIQIANVVTRYGEKKPFVRNVFCLDTTSPIVATQILEFEKEEKMLSEWQKFLIKVDPDIIIGYNIANFDFPYLLDRAKALKVGGFEYWSRIPSIPSRAKETNFSSKQMGNRDSKATNTNGRLQLDLLQLVQRDHHLRSYTLNSVCSQFLGEQKEDVHYTMITELFNGTPESRRRLALYCLKDAYLPQRLMDKLSCLENYTEMARVTGIPFNFLLSRGQQVKFISQLFRKALEQKLVIPNMRSEGSDEQYEGATVIEPTRGYYDVPIATLDFASLYPSIMQAHNLCYTTLVNKKAIEKFDLKKDDDYIVTPNGDTFVTTKQRKGLLAQILEELLTARKQAKHELAGETDPFKKAVLNGRQLALKISANSVYGLTGATTGKLPCLEIASSTTAFGRQMIMKTKEEVEKKYCIANGYTHDAQVIYGDTDSVMVKFGTKDLPEAMKFGEEAASFVSSKFVKPIKLEFEKVYYPYLLINKKRYAGLYWTNPNKYDKMDTKGIETVRRDNCLLVQTVIEKVLRMMLIDQDVQGAQDYVKDTIADLLQNKVDMSKLVITKALTKDDYAAKQAHVELAQRMKKRDAGSAPGLGDRVAYVMIKGAAGAKNYEKSEDPIYVLENNVPIDTRYYLDNQLAKPLGRIFEPILGETKANSLLTGAHTRTIAVSAPAVGGLMKFAKKTQTCMGCKKPLRGKEESAGAVCSDCAPRVGELYKKTLDKTSDLEVRFGRLWTQCQRCQGSMHCEVICSSKDCPIFYMRMKAKKDLEDAGKELKRFDFDQAAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMA2</accession>
    <name>A0AAD8XMA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_567366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370110.1">
        <property type="nucleotide sequence ID" value="XM_060503948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMA2"/>
    <dbReference type="GeneID" id="85387847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18747" checksum="373485652C8C56BD" modified="2024-05-29" version="1">MQLHPRTSTPSASTVLRDFLNQAKCTCCTVRVVELTKQRAVVEWGSVPYFTARGKRAEFVYYTAERVADVRPDLLRTWAAGRPGAGAGETAEWIRDRLRDSWLVEQLAYWVEFLEEWKSYREWYVYKPELFEGKEPDVLSPGCEGCVKPHWPGGLRRRASSCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM6</accession>
    <name>A0AAD8XMM6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40-repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_603049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370153.1">
        <property type="nucleotide sequence ID" value="XM_060507205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMM6"/>
    <dbReference type="GeneID" id="85391104"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000733">
        <property type="entry name" value="WD40 repeat-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051859">
        <property type="entry name" value="DCAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847:SF7">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="380"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="427"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="620"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="646" mass="73124" checksum="E43E145FDD54798A" modified="2024-05-29" version="1">MDDSGDSMRSPSASMNLIEEDDEPAWTYTYDPEDAEGMDDDDEYDPDFQDEPEEEDGDDDDEYHDAEEGEDSNVEVEVFMGAGDEDDDDDAEEDGMAANPISRLMTLITGAAGNGTGFLTRAQLLGLIQSGEVTLRSTLDDEDDDEDIGWGRRRRRPRAREPNRFPKVPSEEGTKLMHSGVFGANDYRVTKKKQLARRILDRELGLGDRRDRKQNQDLMAQGMIPSTNPEMIVHYDDPVYSGQFSDDGNFFYACGHDFKVRMYDTSNPYNWKYYKTVNYPWGQWTLTDASLSPDNRWLAYTSIQSNVCLAPTDPNDTGDPYTLDLAERSAGTQHAGWRSRHSFGIWSVRFSGDGRELVAGTNMQSIVVYDIESRTVLHNVVGHEDDVNAVCFADKSSPHILYSGSDDATIKVWDRRSMGDGRPAGAFVGHVEGLTYIDSKGDGRYILSNGKDQTMKLWDLRMVMSTAKYDEVNPTRLTSNSDFDYRWGTYRDEDWFPHPNDNSLVTFRGHRVMRTLIRCHFSPPSSTNSRYVYSGSQDGKVYIWNMDATLAGTIDVRKATKNSRPLERRYRVYHGDDFPGWNTCVRDVSWHPNAPVLAASAWNGYNMAHGTCTLHSYNEAEDDEAEPPMGRNVDEKLRPVGESFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMN3</accession>
    <name>A0AAD8XMN3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylethanolamine-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_399833</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370320.1">
        <property type="nucleotide sequence ID" value="XM_060502837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMN3"/>
    <dbReference type="GeneID" id="85386736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF141">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042144996" evidence="3">
        <location>
            <begin position="18"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="31675" checksum="4063C60F0FF1B523" modified="2024-05-29" version="1">MLSKAIAVLAAATLTSAATPMGFMPQSNTPLIVSYGGISALDGVNLPRDSSQTQPTIATEQQLKGQYAVIMVDIDVPTNQPPKTGTLLHWMQTGLMSADTPTTLNTTAGPKKVFLMQNKMNAAALAPYIGPNPPAREPLSHRYTFVAVDHTMITQQGLMALSGAAQSRRDFNVMNGLMAAGLSDKVVAGNFFRVTNAGPVGAGQGTGGGGGRGNSTGGGGGMQPNPMPMPAPAPPAGTPTTPGGGGMPGMPNMPGMSMAPGMTMPMPGMPGASAPPVGGAQPSNPARASGLSLAPSLGIMTMGLCLVGSLFIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMV1</accession>
    <name>A0AAD8XMV1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_647027</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370306.1">
        <property type="nucleotide sequence ID" value="XM_060510034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMV1"/>
    <dbReference type="GeneID" id="85393933"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF189">
        <property type="entry name" value="CYTOCHROME C MITOCHONDRIAL IMPORT FACTOR CYC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="8">
        <location>
            <begin position="211"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="396"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="63925" checksum="5497974C47448362" modified="2024-05-29" version="1">MFIDPGCFRPAELAHSELSSSTFLTIHCTSFRKRLLEKLRASLFRKALLQIGSGGAEKVMGASAFVSAAGAALRPIAGRSLTHIRPQLRATPAAAAASRSTTPATTSLHLTQPSRHFSAWANRRTTPTSPSALSSSTTTRHHRLKSTTPSPTAPQPHRPPKRRARTFISPRYLPVFLLLAVGGIAWDAQWLFPSTPQSNDPAEQTALGPARKFIPFDVVAREQVSPTSFILTLKVPPSNSSNVASVSSLWDIFDLWCVEVKQPQIQVAREYTPLPPIPGSSYDEDTLRLYVRAVRGGEVSTYLSRLAPPSSSSSSSSSDGIATKGDKVELRGPHGEFDIRSRLGKRGDRVVFLAGGTGIASALQAAHAVLPLPDGPSMTIFWAVRSRDEIREQLAEGNTVPPQVKPSSSSSGSWWNPFSSSTRNTPGPQAEALLSADTLAAPSPISRDLLALKVKYGDKLDVRVVIDQEGTAVREADLSAALTLQSSPSASAGTTPTHAVEGCKFHSQTAHIGMVDGAPNAGKRSLFKQDDCACSADDAAPRGKNLFVVSGPEGFVQAYAGAKLWRDGGQLQGPVGGMLGAMQRRNPDILKDWIVLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN47</accession>
    <name>A0AAD8XN47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Galactose-proton symport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_646823</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370523.1">
        <property type="nucleotide sequence ID" value="XM_060510016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN47"/>
    <dbReference type="GeneID" id="85393915"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053201">
        <property type="entry name" value="Flavunoidine_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350:SF19">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Post-SET" evidence="4">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="30169" checksum="D994562FBE12DD55" modified="2024-05-29" version="1">MAPLTPHWTQPSHADIQDVIKASETEFLTKSFSKVSLPPFAVYAKMSFPPCDLADKPTYATVQCGKAKHLNLNSDLLYINHSCEPSLVSHAAKKAQTSTFKFPQNLPRVGDRDILEDIFDTGNFNVLAGPKGLQPGDELTFFYPSTEWHMAQPFDCFCGTPSCRGKIGGARDMSRAQLEGLWLNGHIRELLEERDSGARSENDDPTAQALRDALKAAESVVEAARSALRSYTESTTGNSNGAQQHQQTAKNGVNGSKAGRNGASARELGGELGGDTRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN52</accession>
    <name>A0AAD8XN52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_747314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370587.1">
        <property type="nucleotide sequence ID" value="XM_060513416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN52"/>
    <dbReference type="GeneID" id="85397314"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="248" mass="28976" checksum="DBE36186A787CF7E" modified="2024-05-29" version="1">MATRRWYLETSPDGKYQFVSLKRSRSHHHHRHHHHHEEPAPAPAPCPTPTPAPPPPAHHCCRDDCAHITAPEHNDLLDRERKLREANDALARENYTLKCDLQASDVEGRRLSALLISAQAENQLLREDNASLRRTIESSGGNAGKYLREVERLKNKLQKVERELAARLRHGPHHHHHFGHGLGHGVAERIEELRRIVRAWEGKYDGVEEQNRRLRRELHEQRCVVAGQDERIREYERILRRHGFSRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNH9</accession>
    <name>A0AAD8XNH9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_600396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370785.1">
        <property type="nucleotide sequence ID" value="XM_060507032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNH9"/>
    <dbReference type="GeneID" id="85390931"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000014">
        <property type="entry name" value="Proteasome subunit beta type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="29034" checksum="D3C1A4F439292368" modified="2024-05-29" version="1">MDHRPQAWGRPRDDVYGAYDGSYMNTNGPNQATQAPIVTGTSVIAIKFSEGVVIAADNLASYGSLARFTDVKRLRTFANSTVVGFGGDVSDMQYLDRHLSGLDIEESYDLANDAPARLNAANLHKYLSKLLYKRRSDFDPLWNHLLVAGLDDNNKPFLAAADLLGTTFTSPSLATGFGSALAQPIMRRYAPDEETAAKLSKEQAVDVIKECMKVLFYRDARSSDSYSIAVVTKDGVDLKESEKLEKQSWKFAERIRGYGTQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNI3</accession>
    <name>A0AAD8XNI3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Replication factor C subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370664.1">
        <property type="nucleotide sequence ID" value="XM_060513428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNI3"/>
    <dbReference type="GeneID" id="85397326"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000030">
        <property type="entry name" value="replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000002">
        <property type="entry name" value="Replication factor C subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000136">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22534">
        <property type="entry name" value="RFC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="39919" checksum="62C15BF245EC4D49" modified="2024-05-29" version="1">MALIVDKHRPKSLDALTYHQELSDRLGSLAQSGDFPHLLVYGPSGAGKKTRIVATLKELYGPGVEKIKIDARVFQTSSNRKLEFNIVASNYHLEITPSDVGNYDRVVVQDLLKEVAQTQQVDQSAKQRFKVVVINEADHLTRDAQAALRRTMEKYSPNLRLILLANSTANIIAPIRSRTLLVRVAAPTHEQICEVLAVSAKKENWPMVKGLHMRIAQESGRNLRRALLMYEAVHAQNEKVTDSTPIPPPDWEALISQIAREIVDEHTPARILQVRAKLYDLLTHCIPPTTILKTLTFKLIALIDDALKAEVIKWSAFYEHRIRMGTKVIFHLEAFVAKFMRIMEMYLMSMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP22</accession>
    <name>A0AAD8XP22_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_336690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370869.1">
        <property type="nucleotide sequence ID" value="XM_060502453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP22"/>
    <dbReference type="GeneID" id="85386352"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="428" mass="45448" checksum="AD38B554F250FB60" modified="2024-05-29" version="1">MDGQQRDDRAGHNFQNNRMSANGPQPAAGPRRRNDDSWVEVSSQPSSSSLSSIGDEIVTTGLRVGGSMAARRRRLHHQNQPVPRSFHVDQTAIHAGTSSQEEYEESESEEDRCLTSSTENVRPPVRASFQQQPSAQEDSEDSDDSDEIATALGRVSDDPVFRPQPNAFSHPPSGLDRRHSASSAIHQHPHSGVRPALSQRSQTRVSRGPPNFMSPAYQADNDAALRASLTTLLSCAAAARGLPKYKDTTERQGAPPAHAGVGPSSQPVELRLMPESELMAERPTQPQTASPSKSPAARPSRTAVSSAPSSPKSDGVDKHKRTSSSQIRSSRATKKKKVVANEDALISPTLLTWVVSAGVVVLVSVVGFGAGYVIGREVGRQEALSAGVGVNASAVADSSSCGREVIRSSGGGLRRLRWGAGVGRSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPS5</accession>
    <name>A0AAD8XPS5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase-like 2</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cyclophilin-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Cyclophilin-like protein Cyp-60</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase isomerase-like 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_565316</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 22">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371248.1">
        <property type="nucleotide sequence ID" value="XM_060503740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPS5"/>
    <dbReference type="GeneID" id="85387639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 20" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="19">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="18">
        <location>
            <begin position="323"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1731193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="569" mass="62758" checksum="68BF9B4D8393B463" modified="2024-05-29" version="1">MGKNTDKLYITHSEWSSSDAYSASAGANVNSRSRGSFRRLPFNFCAASLQPFKNPVCTKDGTIFDVEIISSWLDKHSTNPVNGEPLNAKDLIKLNFSRNAETDSRSAGLSDGQGDLIDPVTFKVFTDNTHIVAIRHGTYANVFAWETVERMNIKAKNWQDLVDDEKFTRADIITLQDPQNAASRDLSQFKYLKDGEDAILSKEQEEERKNGNVNIDALGRIGDKVLRAKEAVEKARKERDGGTDVNRSSGAVVKAASAGQRKSMVTEKKIPSNAAVYTNGRAAASFTSTGLTPETSGERALLTDEEYMLKPKRVKIKGYVRIETNLGDLNIELYPEYAPRAVWNFMRLAQKGYYKGVTFHRNIKNFMLQGGDPSGTGKGGTSIWGKNFEDEFDGPLTHDARGVLSMANKGKNTNSSQFFIIYRPTKHLDNKHTVFGKVVGGLDVLSKMEDVPTDGSDRPLNKIVMKDVVVYLDPFQEFLKEKSETDNLEKKRQAIALSGGTEDDKTTWTGKRIRADGTVDSGSAGAGVGKYLKSQGSAATDKGAADLDTWEEPAKKKFKSGGFGNFDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQA5</accession>
    <name>A0AAD8XQA5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_564659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371491.1">
        <property type="nucleotide sequence ID" value="XM_060503665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQA5"/>
    <dbReference type="GeneID" id="85387564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF2">
        <property type="entry name" value="HELICASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="883" mass="98120" checksum="9FEFDAF7B4ABBE58" modified="2024-05-29" version="1">MATLSDDDVEKLFSGAPQYFARSEGHYTGAPHPSVAFPWDESLEIRDLTDHVQIEDAAWSCITAWPHITRDMNSNPAAIRCAKERKRAHFYPRCRERPNMLSMQGLEKGTMGYQAALEMPVGDALQEEQFGFDSIGSKAKAIVEQRQRMLASKDGLRRLEESSILDQLIKNGARYKENKVHRKIHNTLYNELFLGILHPPTRVIDHHDPYSLSVQISALVKVLAAPNVWIDFSHVEWRIRLGQILWGSFEGDELETDVEIDDADSNEERKEERYWLLLQILLACELLIRLDAITEGEELGIESIRPTEIKRFEKDANSTVKWSLHLARAWLENIEIIERKVDPANTQKRNSGGWLASLTGKMSLHPNNHAHSHGDVSVYTIQGRYSERQVNGLTNFARKLRWPDIESDTYAEQISETVNKVSEATPIHTPAETPMSIDTKRSSYFGGGRTEASVTRHPSGKHKISAALHPSGWLSKSYVSGLMLPGEGLYHLIMTTLLENDKEAMSKLGPMANLCGGFVYRGKSFWSTACIIGRVLAAGAGSAQCMGWISSDITPQGHGDGWVNIDVAEVCDDMKKIGKQARLWGKTHVERESCVLGDADPSSVLPADFIIPYENNYVEPPPSLSISLTSLNLSAPVDSARTTPTEETVMTPFSDVTRAHELYTYPASISFSVGPNGGEAKEHQFSLTKDIHFVTAHPCHPSSHVKVLRSPSSPTIQQIDVDGSGIGGVSSKPATITGHPLHKFFTYTVIHLSELLEKPDASLDSLLLNTSSVRRPSLTPNMNTTPRVLVIDCITGFKRQAPTQETPTSPILERTANGASLATTNMHLESRRRQFGSDMEVLVRAFCAEKGWNAIISRRRRGCLACAIREAGALAWKVIIRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQN3</accession>
    <name>A0AAD8XQN3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_11458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372027.1">
        <property type="nucleotide sequence ID" value="XM_060501116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQN3"/>
    <dbReference type="GeneID" id="85385015"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="14027" checksum="FF84325512ACD0E3" modified="2024-05-29" version="1">MKLRSKTTYSLDYVNNHLRWAVLPTEVRLTILEQVEIGNKGHDLSDWASVSREWRAFFETQIFQHMKLRYPGPDIDNLSSNVHIYCRDLVKEISLHVCLEEYDNLFNQAPKKLFISLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR10</accession>
    <name>A0AAD8XR10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD dependent oxidoreductase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_714841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371921.1">
        <property type="nucleotide sequence ID" value="XM_060511676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR10"/>
    <dbReference type="GeneID" id="85395574"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF26">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_5G13940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="50"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="39063" checksum="5DACF4BBF9742F83" modified="2024-05-29" version="1">MAQIVVIGAGVIGLSTAVRLQQDGHKVAIVAKDFPSPFETVDSKASINYTSQWGGAHNRWVIPANDMEKRDHAMALRTFQHMESLVKSNPEAGITFMPGIEYLDDPPAQYQALSEEKAQSLGLVDFRLLNPTEYPDDKVKWGCEYKTWCVNPMIYCSFLLRKFSWNGGQIFRRELSDAREAFSMKELPNVRHVANCSGFGFGDPKSFITRGQTCAVANFSPATVTRQNADGTWTFCVPRNFHGGTIVGGTKEPDNWDTEPSPEVREKLLKHFAATYPKILGDDGEFRVLKDVVGRRPTRKGGMRLEREEVGEKRTIIHAYGLGGRGFEMSWGVAEGVLELLGDSKIMPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Z3</accession>
    <name>A0AAD9D0Z3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_568281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369516.1">
        <property type="nucleotide sequence ID" value="XM_060504047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Z3"/>
    <dbReference type="GeneID" id="85387946"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="29"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="6">
        <location>
            <begin position="264"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="6">
        <location>
            <begin position="288"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="108"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="415" mass="46183" checksum="36571AF3E95D8662" modified="2024-05-29" version="1">MWIAKRMASTNVGSSPALTFELVARCSTTRARASVLTLPHGQVQLPIFMPVATQASLKGLTPEQLEETGCRLCLNNTYHLGLKPGQDVLDKIGGAHKLQGWKHNLLTDSGGFQMVSLLKLAKITEEGVRFLSPHDGSPMLLTPEHSMSLQNSIGSDIMMQLDDVLVTTSPDAARMREAMERSVRWLDRCIAAHKNPKTQNLFCIIQGGLDLEMRRECTREMLARDTPGIAIGGLSGGEAKTDYCRVVETCTELLPDLKPRYVMGIGYPEDLVVSVALGADMFDCVWPTRTARFGNAITKHGVLNIRNWRYENDYGPIEEGCGCICCRKGEGGLGVTRAFINHNAGKETVAAHLLSIHNVWYQLNLMREIRQAVIEDRYPALIRQFFGDLYDYDKSKYPEWAVESLKRVGVDLINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1X6</accession>
    <name>A0AAD9D1X6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Family 15 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_600852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370892.1">
        <property type="nucleotide sequence ID" value="XM_060507059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1X6"/>
    <dbReference type="GeneID" id="85390958"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="1">
        <location>
            <begin position="297"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="685" mass="77882" checksum="9AA98A7FA02F1DA4" modified="2024-05-29" version="1">MAQQCSTRHVAGSRAGYLPIEDYGMIGNMHTCALVGTNGSVDFMCWPDFDSPSIFCRLLDQEKGGFFSICPPPSKLCTTKQQYLPSSNILQTRYIHDDGVVDVVDFFPRPKTATVISKSTRQGAFRETTKIQEELKKWLVRRVECIRGRLQLDIEIFPAFQYASESHVTTIIEPTHTANSPSKAVTFHSEHYKMQLDVTIDDVVPESEADAPTAPAAPAPAPSITFRKEKRDGMLGEGVVAHLEITEGQAVSFVLRNDKPDHVTENVTTAVLDGQQHDTQSFWYNWISKSKYKGRWREVVNRSLMLLKMLTYEPTGAIVAAPTFSIPEDIGGVRNWDYRFCWVRDSSFTIYILLRLGFSAEADAYMDFISERFVKSRGPSGELPIMFTIRGETEIPEMELDHLEGYRGSKPVRIGNGAAFHQQFDIYGELMDGIYLYNKYGKPISWDQWCSVREMLDFVLTLTDQPDMSIWEVRNKKQNFTYSKVMLWVAFDRGLRLADKRNFPCPNRSKWLEARDNLMEEIMEKGYNKEMKCFVQSYENNTMLDSSILIAPLVFFIAPNDPRFLNTMDRILMPPEKGGLTSTGLVSRYDTELSDDGVGGREGAFSMCTFWLVEAMTRASVYEPKYLVRAVNLFENMLSFSNHLSMFSEEIARSGEQLGNTPQAFSHLALISAAFNLDRVTGFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D236</accession>
    <name>A0AAD9D236_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_746890</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371087.1">
        <property type="nucleotide sequence ID" value="XM_060513336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D236"/>
    <dbReference type="GeneID" id="85397234"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050218">
        <property type="term" value="F:propionate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="76"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="554"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="698" mass="76378" checksum="8E07ABEEFBFFBA51" modified="2024-05-29" version="1">MDNLHPQDEVLRHSLEDPESFWAHQAEHLHWHKKPSSTLKVTKKTLKSGVTHDSWEWFPDGEISTCFNCVDRHVHDGRGDAPAIYYDSPVTNTKQTITYKQLLDEVEVFAGALREEGVKKGDVVLVYMPMIPAALIGILAVSRLGAIHAVVFGGFAPAALAQRIEASQPVAILTASCGIDGNKPPMSYKPLVEEACRISKHKPSKVVVWQREQIRWNPIKRNDGERNWQSIVKSCRARGVRAGCVPVKSTDPIYIIHTSGTTGTPKGVLRDAAGHAVGLHLSISYLFNIHGPGCVSFTASDIGWVVGHSYIAYAPLFTGAATVLYEGKPVGTPDASAFWRIVEEYKVNTMFTAPTALRAIKRDDPENKLFKQIGERGGLRTLKGLFLAGERSEPAIITMYQDLLETYGAVDAHVVDNWWSTEAGSPITGRALVPHAGKDRGTDVRGHPPPKIKPGSAGKAMPGFDVRIVDDDGRELPRGTMGNIVLGLPLAPTAFRTLWQDEERFYKGYLKRFNGKWLDTGDAGYIDVEGYVNVMSRNDDVLNVSAHRLSSGGLEQAITSHPLVAEACVVGIPDALKGQLPFAFITLSTPEHPPLAVPDAKLADEINALVRSQVGAIATLGGLIQGKGMIPKTRSGKTLRRVLRELLENAVHEEFEKEVQVPSTVEDAGAVDVAREKVREYWEVRGDGHKSTEARAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2A1</accession>
    <name>A0AAD9D2A1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S5 DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_601867</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370699.1">
        <property type="nucleotide sequence ID" value="XM_060507128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2A1"/>
    <dbReference type="GeneID" id="85391027"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="6">
        <location>
            <begin position="325"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="489" mass="54556" checksum="0F8F2681AAD38C6F" modified="2024-05-29" version="1">MNSVRPARSVLSRCVSSASSAPAALPYRLFHSSVSRSGRRRSRFNNITAERMGLTTPDAIEKYAKQHFPEYTEQQKEFLKEKYTPEQWEALQAAEEAIDPKDLVIQGRLRTDPYTQPYIDDFSTVQPIIDAKPQAPAKPVEPKWLPRRMWIDDYIEKMADRVGSQMQDTMGKAFAKALRNISKTNPAKLDFTEEELHELETNPELRRKFLVDNEADVLGAKKEKKAGAASIATDDWLKQFDKEFFDELEGSLSTSENPLRSRVALWKEADGKGTSALAPELGKVEGVKGLYQPPEDVEDDGLDPTGRFIKLKQATGMKISDILSILTKRVVIRSVSNQTRLGKIRSASVIVVAGNGDGRLGLGEAKSTDPGIATATATLLAIRNMKPIRRYENRTIYGNVETKISGTVVQLFARPPGFGLRVSHRIFEMARLAGIHDLAAKIPRSKNPYNTVNAVYKALMNQPDPEEIAIGRGKKMVDVRKVYYGGSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2F6</accession>
    <name>A0AAD9D2F6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_747335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370611.1">
        <property type="nucleotide sequence ID" value="XM_060513420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2F6"/>
    <dbReference type="GeneID" id="85397318"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="48945" checksum="5582598DA90D8EDF" modified="2024-05-29" version="1">MELMELVENEPTARPFQCDWQSCNKSFNRKSDLQRHYRIHTNERPYSCTTPGCGKSFIQRSALTVHIRTHTGEKPHQCQHIGCGKRFSDSSSLARHRRIHTGKRPYKCAHDGCLKSFCRKTTMVKHQRRSHQRGLHPNELLDDCTSDSDSGESPSTPKHAGMQWPPQGVMAMNHPGMGHAMHRAASFADFGQHMNGYPMPQQHQQQHYGAHRHSLSSGGAHEVHGMVHDQQHPGVHMLQRTASMGQHSYYVTEQGNPGVATMNTAMPQQYGQVPRQQQPQVDVPYSQPGMNQSIQSSPSSFSAASGRSPSIQEGFYTHQPTQAATYALHHASPVLEQQQAGMVAYPHQQMQQQIHTPQPIPTQAPQPPPQQVSQYASPTPQAQPEEYWNGVPYQAPVEVATIGQLPTYGSGVYDPWGGPKIEFEDPSMQLPSARIENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2X1</accession>
    <name>A0AAD9D2X1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HEAT repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_243238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371284.1">
        <property type="nucleotide sequence ID" value="XM_060501881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2X1"/>
    <dbReference type="GeneID" id="85385780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001401">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052587">
        <property type="entry name" value="TELO2-interacting_protein_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057566">
        <property type="entry name" value="TPR_TTI1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016441">
        <property type="entry name" value="Tti1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049362">
        <property type="entry name" value="TTI1_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460">
        <property type="entry name" value="TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18460:SF3">
        <property type="entry name" value="TELO2-INTERACTING PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24173">
        <property type="entry name" value="TPR_TTI1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21547">
        <property type="entry name" value="TTI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005250">
        <property type="entry name" value="UCP005250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TTI1 N-terminal TPR" evidence="2">
        <location>
            <begin position="16"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="3">
        <location>
            <begin position="748"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1077" mass="117271" checksum="AB0EC709A3843CB3" modified="2024-05-29" version="1">MATTPANATPARNEFFQQLKPCCVSISQLAIRQQGDSSSFKRLSELTDELYHILNDQVNRDATVLDSRLADYVFFPLSHIFRSHDQYPKRLIELAIKCLTVIIIHGWKSNISPQILQQLLILLTFIVGGVPGREREHDVPEETELESLRALTALITVAGTSSTAATALTEEKLVPTLGHTITVLLGCVADGRTSAIQLEALRILNCFYTSIKDHAALASFLPGLVSGLTKLLSKPQREKTRVLVGSIQSLGLVLVRVLGDVRTRSITARLNSDTPPEAEQGGVLSPSWLNATQSQIKLALATVLKLRTSDTTDVREALLAFCLGLLDECHASLENCSSVLVETAMVISPTHPTTSLTGTSLQDLAIIYPELGETMKVTCYNWIISLPRIMQSASESKKQAAVQNLMKGMALVSSLQLDSSLLDESIAAALRDSVTSLITGAKPSKILDETTPDASWYNQDIVRMGDFSKRYSNVLLGEESQVETRSAMIDLLSNVGTASQQTRLAAEMLDHARDSSGDSQIASFWLSFELLKTAFSRSNELDDLLDFSSLGSGGEGSESIFQELYAFAVVLLDSHSELAEIDWRLEATALEVTAFAASRSGEAFRPELIDVLYPITAFLGSASSQLREHAITTLNVLAVSCGYTSVSELIIENVDYMINSVSLRLNTFDISPASTKVLVMITRLTGSRLLPYLDDVVASIFAALDNYHGYPVFVESLFAVLKEVVEQGVKSDRLLLEGRKNGPESHKKAAGSHVTIDDIVNLLKRRRERETEASIDDVTDTTNNNHPQKPWGAQVQKPKDGGEEGTDEDAANNEVEKEKPPKTPTYTLLEKIAGLTQHYLTSPSPTLRKSLLDLLATVSPALSGDEDSFLPLINAVWPVVITRIYDEEAFVTISACDALCALSATAGDFLASRIKTEWWDGLGKWCRKKELEAIQSRGKGSTHRESTRPGQTAATTSQGIVIPVMTGSDRLSYQSAEITKGSVSGGLGKFAQSAQIWDSVIRMLTAIASHVRLDAEIFDEVLDLLSEALGQNVEARRALEAVNGDAVWLAMYQQGQVKAPSLPKLDGVTFAPLTTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D342</accession>
    <name>A0AAD9D342_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_773403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371345.1">
        <property type="nucleotide sequence ID" value="XM_060515404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D342"/>
    <dbReference type="GeneID" id="85399302"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="740" mass="76661" checksum="DDA4D311E270B402" modified="2024-05-29" version="1">MMPKRPNNDYRDHRGYYREDDDLTVTEGAIQREQKDWSTYRKTDPFILISLAILIATLMGGGIAIGIHFATRGSPNSQVPTSDSHIVPRFAGMNYNAYGFNGTLTHGINSTLSGLATTGTPTLCEDDADETITVTQFLGNNKTASVDTTITTHVQKTLTQTLHKSSMGTTVSSADPVNTTLSGSSVVTQSIPVVTKVLTTSVTETAYHTATAHQSNVASGSSKSSESVIASTSSVEDAPPIVVTTVGPLPSESSHPDVTSVFLTKTLTQTRKTTIQGGPLVSTEEFSSTTTVTPTTIIKSTIYVTAAPLSSTTQAQCSHEIEDHTVYVTVTETFTPGAASSSSSVQSKTSKVSSSKMSSSTASVSPSTATDTILVTYTVTIDSLYPPSTSPIMSSSSSSEKTSSTLVPASKSTIVVTQVATQTIIVSIGHGTTVSSQLGHAGTPIFTSLASSGSAQASTATDVVVLTKTITSNVFKTISASSSASSSSSHSADVQTTTQTSIVTVTASPSSSASTSSKSSSSQSVESILTTIYLTDRATQTVTIGGMATMTVRPEQSSSTSNSTRTETKVITASASRVVRTYTTTVSGQVFTSLITVWKNVTATATATLSGSGSASSLASITHVVQNTTITATATSVIEVPVTLNTTITITGTPMMHPTAPSTLPPFVNGTAMTSSTRHVPTTYHYPTLSSSTATEQPKSTSTVVVVSGAADKHAEGIMGSCKGCTTWLAIFVLGLMVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3H2</accession>
    <name>A0AAD9D3H2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_167829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371704.1">
        <property type="nucleotide sequence ID" value="XM_060501436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3H2"/>
    <dbReference type="GeneID" id="85385335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CorA-like transporter" evidence="1">
        <location>
            <begin position="32"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="553" mass="62900" checksum="AA04E06E83376717" modified="2024-05-29" version="1">MIGSRSFVVILTNILKHSLETSNLLEALYGERQYESLQERECSLFDHAASVITFWETGKRNQFPKEEEAIWDMETLRLHLHRGDQDPHVRHVFVGADNSRSPLSCSMDMFKLVCSYHQVNHAFLEPVHAFGRQKEPLDLCLAQFKGCDTLSCPAEGSPELPKLGRSGREIQLSYLLRSVESSESGNGVWDWQIRQVANYHSFDVETGRAFWFTIKADEIFEDRIKKISPLLRIPAKTETQDGDVSLYLQASLATHLVYLSWCDENCRQFINETEAGIRTIVTPATRAIVDDLIDKESSFLSAYPKPLRDSRNPTMYSQSQSMSGTLATTIDSEKNKMSMLSRMTNGTSSTLSSWLKQEKSKHADPELGDQYPTCNTTDTSSQPPQPDTWETLNQFRFKDIQTLHKHSDIIHRASLALELDVGVLGDICDFYSQIAATEFREKAACEVSICRFIKEVKSIVRRLETRLHQMRCLAISISQSIQLYERLIQQRTNHVGNWFAEIAHENTKQMQVITDKTLKETTSMHVITIATLIFLPATFVAVRTAYPSLASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3W0</accession>
    <name>A0AAD9D3W0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371946.1">
        <property type="nucleotide sequence ID" value="XM_060509891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3W0"/>
    <dbReference type="GeneID" id="85393790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="16624" checksum="EC09193909F86017" modified="2024-05-29" version="1">MDARALLQSQGWRGSGHSLHATDDRIGLAKPLLLNRKDNTKGLGTKAHFTSDTWWMNAFDEQLQGLDTSKPGQVTQTVTAGRLNQIEKVSGGKWMLYASFVKGGFLEGTIEGLERMKQEGQVEERVREVTGAVAPTSWGISKKHCLIDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5I6</accession>
    <name>A0AAD8U5I6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_643688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000228">
        <property type="protein sequence ID" value="KAK1706290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357796.1">
        <property type="nucleotide sequence ID" value="XM_060509688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5I6"/>
    <dbReference type="GeneID" id="85393587"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="85" mass="9433" checksum="3A2F525C23FE09F2" modified="2024-05-29" version="1">MMFLWNVSRTSSLVRVSRMVMGLIKIVLLGWSMLRLMFGQGRGRTRLMFEVDGVLRLGQTVGLIVWSFPDSQGTGERSGLGASVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U797</accession>
    <name>A0AAD8U797_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_658067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000240">
        <property type="protein sequence ID" value="KAK1705623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357647.1">
        <property type="nucleotide sequence ID" value="XM_060511004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U797"/>
    <dbReference type="GeneID" id="85394903"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="131" mass="13864" checksum="135305BEAC448BA7" modified="2024-05-29" version="1">MPGVDVISHHTSALVSLFCPVLSWGAARWSGASAPLSLLSPESRKRPWAIECGTGSRAIKVAQVRGTTARDGSDRRSGSICLLFFFEESLVMDSAEDRCSVLEDVKVVNGKAACESSAPGYLSSQASELTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7I3</accession>
    <name>A0AAD8U7I3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_593851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000228">
        <property type="protein sequence ID" value="KAK1706291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357797.1">
        <property type="nucleotide sequence ID" value="XM_060506669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7I3"/>
    <dbReference type="GeneID" id="85390568"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20289" checksum="C8BDB9A60CDD8B16" modified="2024-05-29" version="1">MPLFDNRHMMKVHIVQIIVIHIVMGLSGARIFLKGGPVTRTNTMSLGISVKSMVFIIYQIATQHWARGRGWASLKANAILNGLEPVFWGAVVFMSIQGNIQRCVGTSCILSWVIVGCGIFLNLLAAYTAVVSFVDFKYFRRTGTTRGVSVDRKAPMHTEEITSTGSVEDQEMAQPRRKVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8N4</accession>
    <name>A0AAD8U8N4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase signature domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_745969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000287">
        <property type="protein sequence ID" value="KAK1703239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357256.1">
        <property type="nucleotide sequence ID" value="XM_060513199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8N4"/>
    <dbReference type="GeneID" id="85397097"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF37">
        <property type="entry name" value="AMIDASE C869.01-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="32965" checksum="0F8A0A6C811DFA83" modified="2024-05-29" version="1">MQKAMENGILTSQQLVMCYMQRTFQTQEYISSVMQLNPDVMTIAAKRDEQRKAGQVLVPLHGIPMETTVRSYALLGSIVPRDAFVVACLREAGAVLFGKSTMSEWADMRSTGYSVGYSPRVFNPMGSSSGSAVGVAANAIAFSLGTETDGSVIRPAHKNGVVGIKPTVGLASQDGCEHQDTVGTFDCLHNATFGIPWNSFWAIANEETKAQLGSLINLIQENGGTIINGTEITNHVTVVNKAGWDWNWQGKIGHPEKSEYTVVLVDFDNNIKKYLSELQNTKMRSLEDIIKFNYENDGTEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8R9</accession>
    <name>A0AAD8U8R9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkaline phytoceramidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_641646</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000187">
        <property type="protein sequence ID" value="KAK1709118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358457.1">
        <property type="nucleotide sequence ID" value="XM_060509568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8R9"/>
    <dbReference type="GeneID" id="85393467"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF1">
        <property type="entry name" value="ALKALINE PHYTOCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1709118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="30599" checksum="723286BDC77D26AD" modified="2024-05-29" version="1">MSHKHQTLRFASDATAGDGIWGYPTSKANFCEEDYIFTRYIAEFINCLSNATYIYLALKYPRANSKVAVPWYRTLDIQSIGLLAVGIFSGIFHGTMHQETQLLDDLSMLVLAGSLVQPLYAFRQSPAVGAAITTFLWLGIATMAVIYVRSGDIAIHVATFTGLLTFVWPRTLFIVYWTGRYSKEEQKRLMKQFWKACIILIVGFTLWHIDLEYCAELRAARKSLGLPAAWLLELHGWWHIFTALGASWYMRLIRKLTSVERIAIGKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA47</accession>
    <name>A0AAD8UA47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_593806</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9 12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="9">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000227">
        <property type="protein sequence ID" value="KAK1706416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357816.1">
        <property type="nucleotide sequence ID" value="XM_060506666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA47"/>
    <dbReference type="GeneID" id="85390565"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000021">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041775671" description="Peroxidase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="13">
        <location>
            <begin position="186"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="100"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="121"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1706416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="43517" checksum="63F7D8B674D53F7E" modified="2024-05-29" version="1">MKTTSLITAALAGVVIARPGMDINKMMADAKLEARQADGGGPSTELIGDLATLRGRELTATGQAIKDILTAEAPGQDLKSFYDDSDLPPKNSAECREDDCCIWKYIADDMAAQMVGNAGRCNNVARGAIRLGFHDAASWSKSTGGTGADGSIILANECKTRSDNKGLEEICDIMEGWFAKYKRYKISMADLIQTASNVATVSCPLGPRVRTFIGRKDSTTPSVKKLLPDPSDSSAKLFKLFADKSFTPAGLVALMGAHSTSQQRFVDPSRADSPQDSTPGTWDIAYYQQTLNPNAPPAVFKFQSDINVSQDPRTNGVWKAFAAGPRGQFMWNEAYATEYVRMSLLGVNNINDLTECTKALPPFRPGFQQPDEDLLTKVMGSVINSEAIKQALEKGDKIPPNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA75</accession>
    <name>A0AAD8UA75_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357843.1">
        <property type="nucleotide sequence ID" value="XM_060515027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA75"/>
    <dbReference type="GeneID" id="85398925"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="874" mass="94626" checksum="07CC4644EB004667" modified="2024-05-29" version="1">MTHRQAPPQPARSSRPQTEKVSSSASKSKGTKAPAAAPAPAPAPASKPARQTTPIAAPKPVRPVSSHKLQPPVQQWTGNPSPPSYTSFNVPPPASPVPKAGTGGSSAPPKAPLSGLGRVADLRSPGPGALTSFPPPPPTPPQRELTGYFPAGAGQQQKQLSSAQIKAAAARIPASAPNGVLTPPEKAKRTGAPEPRPGVIDFDNLEETLQNLRFAPSPMLSTIYSAPSTPRDELATPDFTASTTTSCFTPPSTNPTPEPVTPLDLTPRGPPPAQKQQQQQQSKKELTMSPTRPRANSRRASPPSRKRGRGVVACIDSPVTFCTTWYTHPTAPDFSICSKCYEDHLVGTRFEHDFRGKICDDNKPRVCRFSKPRVKDHLLRNTLATGRIEDLVSFLLHRSAVPDCRGADGAKGSEGAKWYRPKNNAVPNMVVCQACFEDHIQPYRFAANFEQATGQATNDVWSCDLSTRYIQNIYKEAAVKDDWPGFTKEALARMNLPPCAKRQKVTVTSRKWFTPTAAGHDGVLVCAACYCDFVAGTGEEGKWCDAGTNLASRYGSLVYCALGHFNIGIAMSCATEAKQYSIFWKALDAACNEEFCSPQGITDGTWYTFPSHPAEFGICAACVANVAEPLGLSSSLVLKCGVSSGTTLLCCFNPANPRFASYMTKLLECHFTADTQPLESYALEFASLPLCPRDEDFRDRRWYGWQDCTICPSCYHESIRGTTLATAMPLKGVTVAASLMCEMYSPRMRNLYAQACARNDPSELLRVSKARRAVYVETVPTIRQMIMEAQMALGQQRVLNVASSTSRAMGQAKEAVMPSQGVYSMPGVGFGFSNHFEAQGASYSKQANSIMAEYGSGSRTHVIGTLEKRWREVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAN1</accession>
    <name>A0AAD8UAN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic solute transporter Ostalpha-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_593391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000215">
        <property type="protein sequence ID" value="KAK1707146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357994.1">
        <property type="nucleotide sequence ID" value="XM_060506622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAN1"/>
    <dbReference type="GeneID" id="85390521"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="551"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1707146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="67718" checksum="ECAB4AE4662CB121" modified="2024-05-29" version="1">MNLTCNSTLEELRILPGSEILIAGPLTFHDLALIIAGSCTIIAICLSFYLVFMHSINYTKPREQRQIIRILFMVPVYAASSFLQLWYYWHAVYFQLMSDCYEAFAIASFFSLMCHYLAPDVHTQKDYFRNLYPIKPWVWPLDWFAKCCGGQRGPWRTPKSGLTWFNVIWIGVYHYVFIRVAMTVTAVVTQYFHRYCESSNNPVFAHIWVISINCVAVTIAMYSVIQFYVQMREPLKEHSPFLKVLAIKLVVFFSFWQVTCISLATSTLDLVHPNKVLAYPDIKVGIPALLLCFEMALFALLHLWAFPYAPYVPGAKTTYYPSADSRDSHAPLRENVHTAPAGGWMGLKAVGDALNLWDFVKAFGRGMRWLLCGVKRRHEDPSYKTAASLDMDDLDKSGDTAYHPAGVKSTDHLPIATEFRRSTYLQPSRPPPRPQRPGNESDSLIAHAQPNPSQMSPPRRPARPVSPLSPMSPISPYQDQSFQQQTGMTPVHPANPGPSNGEWGRTGPAAPANLGVAGPRDLTQQRVGEALWGPPQSPAAASIMPESPVLGSPMNGAYGHPALQQQAHQQQAYQNQAFGSQQQPHANHPYGNQTHDQQPGPGQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB31</accession>
    <name>A0AAD8UB31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_83082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359732.1">
        <property type="nucleotide sequence ID" value="XM_060515945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB31"/>
    <dbReference type="GeneID" id="85399843"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="31173" checksum="9BD1542E0C46446B" modified="2024-05-29" version="1">MMSHQDRPSFQHVRIHRQCGACGFLFGIGDHLVALRASSTRIIALDAATFAATGTPQTRDAYLFCRHPHCKICSASAETATVHRDCFNLYSSRTALPDKLYRLLKFSLARYPWPQSTPLLLSPVVNTTQGIANSHLRKLAKLPPELTTMIWGYLGQHALLRLCCVLETIDFAHRKGLDTPLLGPLRQVQFWQRGKLPIIATAGPSKPLQMTIDSRGIRCIERSGCSTAQLRSTFDLYTTVDAENDLTISFQAFNFRPQSTVIDLPLLIWTTAQESRSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB69</accession>
    <name>A0AAD8UB69_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome assembly protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_724198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358590.1">
        <property type="nucleotide sequence ID" value="XM_060512631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB69"/>
    <dbReference type="GeneID" id="85396529"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45048">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45048:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="2">
        <location>
            <begin position="183"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="441" mass="48173" checksum="7E332226AE83399C" modified="2024-05-29" version="1">MSLAVDALDLTRVQHLQRAEEAGESPPYATSAILQEVNSIKEILNRQPASDQNLSPQKLAGFLNFVRTFIDNQSSTVPASDMARLSVTADNAGSSTYSMSAAPSLDGDVNPYPTLLAPAPAHATFRHVGKITMNLEKEPVDIRFTSATDPTSFAVSNFFKDISLFDAASGERRRTIKVKGVNMVFSPLMDLVAVTTEHHDEYVNRFPKTIITSHDMVHFERPALYVVEWVNDNSPNARKFILQWHGIRAFAFSPDGQLLAIKGVRNRVEIVTAAKGQGYSVIRSHTDEVTHAEWTADCTRLVTASKDGTLRITNVETGRNIAKIEMEDWRNPLRLAVSPAGVIASIWGRTVTIWDPESGAMNSYNLETAKGSEGVPLAISPDLRWVVYRSDDGADATDLATGKVVYSARLESGFAVSAAFSGNGQFMVVGRNDSGILNIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBH2</accession>
    <name>A0AAD8UBH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Modin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_591611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358724.1">
        <property type="nucleotide sequence ID" value="XM_060506454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBH2"/>
    <dbReference type="GeneID" id="85390353"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="79285" checksum="8B8DE2A01451976C" modified="2024-05-29" version="1">MADSNSSNSPSDNSNNSGNANGGSDVVVAIVALVVSVVALFAATLQIMQAIFASAKGLPNCTEDVMGGWAGGTTKRPKFKELRLEVRFQAPIIFLAPPKNMSKPEKGDMWSVEGTRDSCTKNRLDYDKIFPREESTSGVNDEKPSKPPEKVHTVDNELATWVYLLIAIERMEKDSKEWELDKIDGEGLPNSIKPNLPEPTLAVKVQAKNRSFDANPSIKKPYATSTISHLIELAAILGLYWRVFDRDNNQYRAEGNGYSLTGSRVPDLGVVFVFEKTGHTSFEERRVIPTSEVKELCFGRVPTFYRDKKDPDEDLEWQREFTTSSGTGIKVEILQLSTRDAIAETLTQIGCNGKTTLFYREGKKDRHLFSVTFEVIGMLARVLHIEGRCFRFLPNPTIFSWDRDSLSLQRLLIAFSGLLMNDLTVVEEESETVIDERVETAVEDIRALSESAEEMSNDFDENPPLTSKRMSLLHKAIDLADKSLKKRDQGIVLDVLRRHLQEVLAAINVPEKRGKEQISFRDLLGIPLEMREQRFMETYFERILWRVVPTNSAKRGKRDDEVVSRAIHDDTEKRISRLGIGSPQAGSAIPPLPLRLNPGESPTKALDDSTPTPGISRVKTWPHRIQTEQPSDQPEPPQPSKMPELPQWETIVPNHIEMQRLAIWYTLVFRMICWLMLHDFDKKDVQVSKSELIGNRQPVFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBU5</accession>
    <name>A0AAD8UBU5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_641304</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358594.1">
        <property type="nucleotide sequence ID" value="XM_060509548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBU5"/>
    <dbReference type="GeneID" id="85393447"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042115975" description="CFEM domain-containing protein" evidence="16">
        <location>
            <begin position="20"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="377"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1709460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="462" mass="51511" checksum="4CB72B1CE603FE20" modified="2024-05-29" version="1">MKQIVRVAIVLLFAATAQANVPSLNTTEITKLLATTPKCAMPCFVDAFHSGNCTLEGLTDCVCTNIPLQARASACIQQACEFDDQVATARISQQLCEGYPYPDRRRFSKVFSIGLPVITILTVALRCLARLQVTNRLWWDDWTALIALAFLIVMSGLGYANAAMGFGLHYWDIDPGNGKTILQIFYVLQMLYIFIQVFAKASIACFYSRVFTNQKFRLAVKLFMVFLFVHGFMFLLLMVFQCLPIESIWDRSIQGRCLNVSAISYGGAACSILEDIILIVIPIPELMKLQLGKKKRTALVCMFAIGSFACVASMIRLKYLVSFANSFDSTWDNVDVVLWSSVELNLAIICGSLPALRPLFKKLPIFFTTIRSTIQTGTHRRKSQAQSTTAVRKSHHSHASHGSSTQSSPCNSPQKPQAVKLRDFGGSSTTCDKDTHYSLEMTTDEESKDDLERQDWARAYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC07</accession>
    <name>A0AAD8UC07_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-binding monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_590997</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359010.1">
        <property type="nucleotide sequence ID" value="XM_060506390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC07"/>
    <dbReference type="GeneID" id="85390289"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051820">
        <property type="entry name" value="FAD-binding_MO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43872">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43872:SF1">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1711207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="55507" checksum="0D90AD35505B3542" modified="2024-05-29" version="1">MASTHPADLKVDEIYDYVIIGAGISGINTAYYLQAHGPKNASYAILEGRPRMGGTWDLFQYPGIRSDSDIYTFGFSWNPWKGENHLAGGPEICAYLEESASEHGIDRHIKYNHQVASADWNSATCRWILKSSVAGGVEGASEKQQTKTIAARFVVLGTGYYDYEQPLAAAIPGIDTFQGQLVHPQFWPKDLDYTNKNVVIIGSGATAVTLLPNIATDAARVTMLQRSPTYIIGMPSRKAGLQRFMLSILPKSVSSRLLRVQYFMLSYILYYYCQWFPGSARRFLLGAAKKQLPPNIPLDPHFKPRYNPWEQRLCVCPNSDFYQALRSGKADVVTDTIEEVTGSGIVLKSGRVLHPDIIVTATGLKIRFAGSIALSVDGRRVDPNTKFAFKGCMLQDMPNMAYVFGYANASWTLGAEATSSFLVRLWRGMEKKRLRAVTPLLEDPNMKPNAMMPLKSTYVRNAAKVFPKAGSGRWAPRKNYLMDLWTAMTSDVFAGMKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCC4</accession>
    <name>A0AAD8UCC4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Xaa-Pro dipeptidyl-peptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_656979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358938.1">
        <property type="nucleotide sequence ID" value="XM_060510924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCC4"/>
    <dbReference type="GeneID" id="85394823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase C-terminal" evidence="2">
        <location>
            <begin position="198"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="379" mass="42087" checksum="B4A028C694F060C1" modified="2024-05-29" version="1">MSSPLRLQGYSRVLRIMLTSLQTLCGNAHNAMKLTSLETSILTQLEVPSSSPANSESLAPFVSVFVRLDSYMKGVRNADSLVSDSAGKSLTIEQLLQTEDHVQPKPPPFRHMRPCPSVFSNLREANRHLETLENLCLFAVEQQGGPRDVQNAHICGVSSGHGSFEAFRRIASKEKWLRVHNTQEWTDYCTSEHLVDLQQFFDFYLKDEDNGWQPNPRVRLAVLDPGSEDTLDRVVADWPVPGLQSKALYLYSNNSLSESSLSNEATLKYNSSLASGVTLDYRVPETMEVTGYSKLRLWVSSPDFTDMDISISVQKLSTNGTAFPSTGSESSSTIGPTDALPVSHRELDIKRSTDLEPFLLHTSERLLSPGEIVPVDIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCF5</accession>
    <name>A0AAD8UCF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_590396</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359250.1">
        <property type="nucleotide sequence ID" value="XM_060506334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCF5"/>
    <dbReference type="GeneID" id="85390233"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="12"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1711926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="55307" checksum="B79B568A5E263524" modified="2024-05-29" version="1">MALPPKWYQFLVSVFASLGSFNYGYDLGVIASAIASASFKTKFGEDPNEIGAVVSVFTGGGFIGAGLAGPTGDRLGRKKTILIGASIFVLGGALQAAAQSLAFLYAGRALAGIGVGMLTMIIPMYQAELCHPSIRGRVTALQQFMLGVGALAAAWISYGTYIGFAENDNNQWRVSLGIQCIPGGILALLILLFPESPRWLIDHGRLDEGLATLAKLHAHGDINDAWVRAEFDQIQDSIAAEHEGSAKSYKELFTDKSCFRRLFLACALQASIQMTGVSAIQYYSVAIYEKIGIAGDETLRYQAISSVIALVAQFLCMMLIDKTGRRWPLIFGNLGNCVTFIIATILLAKFPPGSPHASGATAWGFIAMTWLYNFSFSATCGPLSWIIPAEIFDMKTRSKGVSIATMTSYAFNTLIGQTTSVALDDKHGIGWRWYILFIVCNFTNALFFWAFLPETAKRPLEEMRYLFTEAPLFIPTLDMSTVESHDLERRVEAVEQKREEHGSEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH8</accession>
    <name>A0AAD8UCH8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PRISE-like Rossmann-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_795883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360497.1">
        <property type="nucleotide sequence ID" value="XM_060515852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH8"/>
    <dbReference type="GeneID" id="85399750"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08948">
        <property type="entry name" value="5beta-POR_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055222">
        <property type="entry name" value="PRISE-like_Rossmann-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487">
        <property type="entry name" value="3-OXO-DELTA(4,5)-STEROID 5-BETA-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32487:SF8">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22917">
        <property type="entry name" value="PRISE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRISE-like Rossmann-fold" evidence="2">
        <location>
            <begin position="4"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="408" mass="44390" checksum="6CF27D900E2863EA" modified="2024-05-29" version="1">MAHALILGASGISGWSLLNQARTYPTPTTFARITGTTNRPLTLEQARLPADDPRLALVSGIDFTKTVDEVAGALRDKIPDVETVSHVFYTAYVNADESKGQAAANIDLLSVAIRAIEKVSPRLAFVVLQTGGKGYGLMYPDKVTLRTPLREDSPRIPRPWADEVFYYAQHDLLQDLSRGKNWTFSEIRPDVIVGFAPTSNAMNMARGIGIYLSVWRHVFGGGAGSGGPRGRVEVPFPGSLRSYRATHTDTNQDVLSKMEIFAAVVNPEGCGGGRAFNVADGGAVTSWSGVWPRLCERFGLVGVAPPPSPDAGTGTASGSSTPPPSMKDFIAKHDDAWVALAREHGLDEGAAREYNWDFLHVMLVECNFDREYDLTRAREVGFEEGIDTVEGYFAAWERMRSAKQLPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD49</accession>
    <name>A0AAD8UD49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_30168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360827.1">
        <property type="nucleotide sequence ID" value="XM_060502255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD49"/>
    <dbReference type="GeneID" id="85386154"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF11">
        <property type="entry name" value="ISOFLAVONE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G12510)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1717340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="34925" checksum="70F2FF4DA91B5D15" modified="2024-05-29" version="1">MATFKASKILVFGATGQIGVFITAALLDASPSFDQITIFTSPTTVERKADLLNGWKKKGLKVIAGDVDDTEQIRAAYKNADTVISALGRNVIEKQIDLIKLAEETDSVKWFFPSEYGTDIEYGPKSPNEKPHQAKLKVRKYIRENVQRLKYTYLVTGPYVDMFLTLPSIAQEAGGFDTAARKAVLIEDGEGKTGLITMKDVGTTLVASLRHPEASFNRALKVQSFVATGKEIVAEYEKQTGEKWEIVYSSLETLKKAEEKAWAEGIPYATIFTLRRIWAEGGTLYEKTDNERIGLGPKDVESLEVAVKRSLGKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD91</accession>
    <name>A0AAD8UD91_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_723466</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359654.1">
        <property type="nucleotide sequence ID" value="XM_060512562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD91"/>
    <dbReference type="GeneID" id="85396460"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="102"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="30800" checksum="B01225033BF0E61A" modified="2024-05-29" version="1">MIIAVCWTFTALGLIFVGGRLFGCAILSNTLVTILVSWGNGKHFTVLNLEQKQNTVKWMIAAYVPRIETLGFPKLAVIALLTRLLAPGKLHLRSMGIICCLSLTAFSAFLDFYLAVYPAVVLWKLHMRFQKKLALTCALGMGIISGCAGIVKATGVPTLSSQDVSYIMFKGRSIWSLAKKSGSYQYNSHSKKSAQQQQQQPQQDSIELRSKPRKKVDVYGFTMHAKEDSEESIVNPGKNAETSSSGRQSDTYPESEDKVVKSSTVTITYDQGEEGPTSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDI4</accession>
    <name>A0AAD8UDI4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_757584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358760.1">
        <property type="nucleotide sequence ID" value="XM_060514914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDI4"/>
    <dbReference type="GeneID" id="85398812"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042061365" evidence="1">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="135" mass="14356" checksum="436363026093CA4E" modified="2024-05-29" version="1">MKLTLAFTALLATAAMAGVAKIRHEDETLEDSYKRRSVKAGIVPVKEEDIISLGDRAVKAGIVPVKEEDIISLGDRAVKAGIVPVKEEDIISLGDRSVKAGIVPVKEEDIISLGDRAVKAGIVPVKEEDIISLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDN8</accession>
    <name>A0AAD8UDN8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">E2 ubiquitin-conjugating enzyme 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ubiquitin-protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_640467</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358835.1">
        <property type="nucleotide sequence ID" value="XM_060509489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDN8"/>
    <dbReference type="GeneID" id="85393388"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23796">
        <property type="entry name" value="UBCc_UBE2G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000008">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="17">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="15">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00077195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1710556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="18754" checksum="ABFA7249F6BC3F3C" modified="2024-05-29" version="1">MAQSTAHRRLLQEYRALTNNPPEGITAGPVSEDDLLHWEALIQGPEGTPFEGGVFPAELKFPKDYPLAPPTMKFLVDMWHPNIYPSGLVCISILHPPGDDPNHYEHASERWSPIQSVEKILISVMSMLAEPNDESPANVEAAKMWRERRTEYEQKVRDGVRRSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDV4</accession>
    <name>A0AAD8UDV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ligand-effect modulator 3 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_797042</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358925.1">
        <property type="nucleotide sequence ID" value="XM_060515882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDV4"/>
    <dbReference type="GeneID" id="85399780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="412" mass="47056" checksum="0AB34C605AD8C159" modified="2024-05-29" version="1">MGRSKSEDLLQLEKPRKPKATPFNQQRLKAWKPLLTPKSSIKIFLALGVVCLSLGIFWLVQNDNIREMRIDYTKCDEIESYNELEVMPPDNVRKRFKASSAGQPVDQWKRSNQSVTFDGVTKNYTLCTIEFFLPEDLQPPVLYYYRLTNFHQNHRLYINSRHKDQLKGDAVSLNSIKSSDCAPVSSRIVAGSAEEKIVYPCGMIANSYFNDTFENPLRIPSGTNRTVPYNMTSVGIAKRVEKGLYQPSKYQVPVTAQSNDSLIVPPPGWAERYPNGYHSGNMFNPAEDESFMVWMRTSAGSSFSKMAMRNKDKVMERGIYRLDVVSHYPIRENRGTKSIVISTTSGIGRRNSFLGRSFLAMGSVSMFFAFISALTLRYRPRRLADHDYLHRYNSQTLQREGSNGPMLRTTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDX6</accession>
    <name>A0AAD8UDX6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_704147</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362442.1">
        <property type="nucleotide sequence ID" value="XM_060511491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDX6"/>
    <dbReference type="GeneID" id="85395389"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236199" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="640" mass="70557" checksum="55DA8C48EB7660F8" modified="2024-05-29" version="1">MKPFSFAFFLLLSGSATGSLLNDTAYDYVVVGSGPGGGTLAASLAHEGHSVFLIEAGGNMGDDPLQQIPGLADVNSEDPAMSWQFFVSHYQNETQARRDRYFTYRLSNGTLWYGIDAPEDATPLGIYYPRGATVAGSAIANAMNVVLPPDSDWNHFAEVTGDESWGPENMRSMFIELERNTYTPEGTPGRGFDGYISTNRNNISYVVDRPGVLRVVQNAISQTEGIEAPDSEQVIELMERDLNRPDSDRYEVPGLYQIPLHVDENRRRSSPWNYIADTLASKREDGTPRYPLTLSTHSLATRILMKNSETGLKAYGVDFMVGEGLYEADRRYDPSVEPQVRTVRAKKEVIISGGAFNTPQLLKLSGIGPREELERFSIPVAVDLPAVGEFLQDNYEAGINVRSNIVWENSPFAECTPGSPETDSCLAQWEAGYGAYGEAAAPIFMLHRSNQSRNADCDLIIFGAAGGVFDGHYPGFSEVAWPSTSFFWAVVKMQNGNPTGTVRLRSSNPRETPEINFNFYQEDADVDIAALSEGIEHLMSIMNVTREPYQPFQVIDPPADRSLEQHIRDHTWSHHAAGSCRMGQNSLDSCVDSKFRVHGVQGLRVVDGSVFPRVPGGFPVGATYAASRKAFHEIVSNDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEA2</accession>
    <name>A0AAD8UEA2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_632243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Involved in mitophagy. Required for the switch to necrotrophic growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The mitochondrial prohibitin complex consists of two subunits (PHB1 and PHB2). The subunits assemble into a membrane-associated ring-shaped supercomplex of approximately 1 mDa. Interacts with ATG24/SNX4; the interaction is direct and plays a role in mitophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361412.1">
        <property type="nucleotide sequence ID" value="XM_060508956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEA2"/>
    <dbReference type="GeneID" id="85392855"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035632">
        <property type="term" value="C:mitochondrial prohibitin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00053189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1719328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="276" mass="30262" checksum="39F15918A02850FF" modified="2024-05-29" version="1">MAQALGFAYRMAVPAAIGIAVVQSSIYDVKGGSRAVIFDRMSGVKDAVINEGTHFLVPWLQRSIIFDVRTKPRNIATTTGSKDLQMVSLTLRVLHRPEVQALPKIYQNLGQDYDERVLPSIGNEVLKSIVAQFDAAELITQREAVSQRISSDLRKRAAEFNIALEDVSITHMTFGKEFTKAVEQKQIAQQDAERARFIVEKAEQERQANVIRAEGEAESAETISKAIAKNGDGLVQIRKIEAARDIAATLSSNPNVAYLPSGGKSGNQMLLNVGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEK8</accession>
    <name>A0AAD8UEK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ccc1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_636270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360111.1">
        <property type="nucleotide sequence ID" value="XM_060509246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEK8"/>
    <dbReference type="GeneID" id="85393145"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="20834" checksum="9AA1547DF6CD3AE6" modified="2024-05-29" version="1">MGLGGYLGAKSEAASYKETRRECTRLTQDDPAMARAQVLEVLEPYDLPKQTLEDVTDHLSTSPRLIDFLMQFHHCEQEPASNRAFISALTIAAGYLLGGLIPLFPYFFVPAEDVYLALYISVAVMAVALFAFGYVKTCIVSGWSGLRCVRQAVVGGLEMVVVGGAAAGAAMGLVKAFDQLAQSDDVSALASKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UES3</accession>
    <name>A0AAD8UES3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_588677</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360049.1">
        <property type="nucleotide sequence ID" value="XM_060506158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UES3"/>
    <dbReference type="GeneID" id="85390057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23539:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23539">
        <property type="entry name" value="MFS TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1714587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="537" mass="57058" checksum="BB7DF89D72F1EE03" modified="2024-05-29" version="1">MDAKDSQPSPRDDISLESLHPIEPNADVNIDDKKDIPITALASPPPTIANVNILDEENAQPGPDLSQVGDEKLKKRARWALFVMSFFMGDVADGLGPFLGVYLQQRGWEPGLRGMVSTAGGVATIIATGPIGALIDATKYKRFLVAGCALLVGVSQGLNLISTHPALVFSTQIVSAVAGTSMMPLLVALTLGICSPDEEGSNMQNKKSKHSFRVLNGRNQAANHAGNMVSAGLAGLLGSKFGLNAVFYLVMAFCATTIASVFLLPERAVDHAAARGGLAPDHSAGNARQTQEREEVDTHDFAERGDMPPPRTPIASPKASFRRLSLKPKFTYSWIKIFQNNWPLGIVAITIFMFHLGNAAILFLYGQALVAAGEGDPAGTTGLTVIIAQGTMVIVSIMSAWASGRYGYWSAVLLSYCVLPIRAAVAGRVMKGWGVWPVQILDGIGAGIQSVAIPGLLAVMMAGTGHVNVTMSIVGGITRQTGAAISHSLAGWVAQVRGYSFALYLMGVFPLVSVFLWAVFYKILRPVMDKKPGENTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFF1</accession>
    <name>A0AAD8UFF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_754841</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361952.1">
        <property type="nucleotide sequence ID" value="XM_060514538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFF1"/>
    <dbReference type="GeneID" id="85398436"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000010">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041924285" evidence="2">
        <location>
            <begin position="18"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="109"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1720441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="24972" checksum="0286BA3A3E9C8FF2" modified="2024-05-29" version="1">MRFSAVAVAALATQAAAWRGQGPPSGSYWGWGNTGAQSSKAVDDCSGAEVTSTSTITLPAATAPPAATSAAPVVTPSAAAPVEEAVSTTSSAAPAATSAASSGTSGLTSDQQAALDAHNAARSDVGVPALEWDATLAANAQEWATHLLSVGSLTHSQVSDQGENLYMQSNTDSPYVNAANAWISEKSSYNGETISESNYMGFGHYTQIVWKSTTKVGLAVATNSQGTYVVARYSPPGNYIGEKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG01</accession>
    <name>A0AAD8UG01_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_756491</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360020.1">
        <property type="nucleotide sequence ID" value="XM_060514759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG01"/>
    <dbReference type="GeneID" id="85398657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF17">
        <property type="entry name" value="DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="204"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="824" mass="92968" checksum="0D90C21D5E05EDFA" modified="2024-05-29" version="1">MAKNDDSAPDLKILGDQITLQPSGYIKPSQPRDDEKEEALMKHMARFRQEPLQFLREVSLYVSGTGWRAYDNAIGQPIFYSGFSDKMKEAVLSAPLLQSRIADLAEKRVAVEEKEGLLNKQDKDFAMKRARRRAVVESGIQEVADKMTDDMICKFESKTFIRSAYYLVTQLTLRAYNQGIHVSSEEVLRLRKVAEEAEKKKQSIIFLPCHRSHVDYVSLQLICYRLGLGLPVVVAGDNLNFPLVGSFLQHAGAMWIRRAFGDDILYTTLVQTYIDTLLQGGYNFECFIEGGRSRTGKLLPPKFGILSFILDSILSGRVEDAIICPVSTQYDKVIETEGYVTELLGVPKKKENLADFLSGGSSVLSLRLGRVDVRFHEPWSLRGFINEQLTRLERLPTGLNMDTKNPENTAIRQKLLRILGYKVLSDINDVSVVMPTALIGTVLLTLRGRGVGKTELERRVLWLTDRVRAKGGRVAHFGAAPLSDIIERGLDVLGKELVGVVKDLPEPTYYAVDRFQLSFYRNMTIHLFISEAIVSAAMYMKVKQGGGPAMQDISFQELQDQIQFLSSLFRGEFIFPSEGLAANLEKTLRDLEADKVLKLHRDDQGKVIVIGLSDHERAVGRENYDFYCFLIWPFIEASWLAAVSLMGLSPPLGQKDDIWIEVTKAQGSAQVLGKTLYHQGDLSYFEAVNKETLKNAYQRFEEEGILQVVKSKDPKVPPRLRLDPEWRPSRDPETGTLNASGRLWDFTEKIASSRREGKNRRDGATVSTRVLRLTDLLGSKLFDAARNIDGKGVSPLLSIEDARQLKKSVKEQRRRRSLENRAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH75</accession>
    <name>A0AAD8UH75_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_721149</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362852.1">
        <property type="nucleotide sequence ID" value="XM_060512353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH75"/>
    <dbReference type="GeneID" id="85396251"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF306">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="87"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="56193" checksum="1D1DDB3F5728749C" modified="2024-05-29" version="1">MPAATEVIQPVSQDLFVRSHKSQNENERTNGHVGDESNSQQHNGRAGHRKPLSTSYPSNSLNFLRGLNFAKDGKTSESTPSTLIALDILIVGAGLGGLATAVALARSGHHVTVLEQAAQLSEVGAGIQIPPNSSKLLQRWGVMDIMAEQAVRPDGISFRRWEDGHRIGFTDLSESFIELCGAPYYVAHRAHLHYALYQRAKDLGVTVRLDSRVAGYNPHLPGANLASGETFSADLIVAADGVKSVARNLLPSNQVGATNYTGFAVYRATVDVSKMRRIPEIAWILEKPGLHVWIGEDRHVMTYTIAAGESFNMVLSHRDSRNPSTWEQKTQAEILGEMRAEFRGWDSQLTKIIELIDTTIKWPLMAGVPLDNWVADSERLVILGDAAHAMLPYMSQGAAMAVEDGAALAVALNNIQNREQLGLALQVFQGERKTRTSMMQEASMVNALLWHFKDGPEQKARDEAMRPEVEGRKFASSPNQWSDPLTQSWAYGYDAEDRMLEQWKRESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHC2</accession>
    <name>A0AAD8UHC2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras small GTPase, ras subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_722027</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361664.1">
        <property type="nucleotide sequence ID" value="XM_060512426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHC2"/>
    <dbReference type="GeneID" id="85396324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001856">
        <property type="entry name" value="RAS small monomeric GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1720153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="29250" checksum="B27DCF65B8254D19" modified="2024-05-29" version="1">MSIPQQAPTPISITICGDGGCGKSSITLRLVRSQWTSEYDPTIEDSYSITRKIDGQNYHLSLTDTAGQEEYRGMWASSNLGADAFLLVYDITSRDSIDALQYFNDLIDMEAETRLDNAERAKRAGLSPSSYRDTVSATPGAKTVPPVKIVAGNKCDLQESRAVPAAMGLDWARRRGCGFMETSARLEVNIEETFALIVRRVVEARRMAELGVNENMEMDRRGMTKPLSPLPAGSEQNEKRGPGVRGPNVEGKVGKASIWRKLRCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHV8</accession>
    <name>A0AAD8UHV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenylalanine ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_705187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361949.1">
        <property type="nucleotide sequence ID" value="XM_060511505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHV8"/>
    <dbReference type="GeneID" id="85395403"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="703" mass="76640" checksum="C0F09D35FC7376B0" modified="2024-05-29" version="1">MLMGHLHLVSGQWKHVQQLLDSHSRVVVDGQTLSLSDVVAVSHYHTPVSLTSDTNIINKVHESTALLRLKLRQEATIYGITTGFGGSADVRTSDHEELQRGLLQLLQVGILLPSDKGSDLYGESHLGMQAWRGHALPTSIVRGMLLVRVNSLLRGHSGVRLEVLEAMLNLLDNHVIPIVPLRGSISASGDLIPLSYIAGVLEGNSDVYVAVGAQRPKFMTAKEALKTMGLEPVRFEAKEALGITNGTATSAAAACVAMHQAHQLATMSQFLTAMATEALRGRQSNYHPFISQCRPHLGQVEAACNILRFLSGSKLTRKGDHHAEGLVQDRYPLRTAPQWIGPLLEDLMLAQQQIQVEINSTTDNPLFDVETETVHQGGNFQALAVTSAMEKVSSCMQLLGKLIFAQCTELLNAKLNDCLPPNLAADNPSKSFTTKGLDITMAAYMSELAHLSHPVSAHIQSAEMNNQSVNSLALIAARNTLEMTEILYLMVATYIYALCQALDLQCLHLEFCSVARPAMLEVAQNCIGFPRAADGADDIARRCGEILLQKWNSLANLDVEDRGRAAAREAKGGQLEILAPYFEGMRPEELIIAFKAMGAYTKQSAERISHEYCKTRLRFSENPSTGAYLGVASKAIYKYVRKTLGVPMHRGLQDYPTTLGTNESPGEPGKKTIGTLTSEIYVALRDGSMHDLLMSTVSSLESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIH1</accession>
    <name>A0AAD8UIH1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Antigenic cell wall galactomannoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_672165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364576.1">
        <property type="nucleotide sequence ID" value="XM_060511128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIH1"/>
    <dbReference type="GeneID" id="85395027"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF4">
        <property type="entry name" value="CELL WALL GALACTOMANNOPROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042237928" description="Antigenic cell wall galactomannoprotein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="34529" checksum="A358460AEAD7CC4D" modified="2024-05-29" version="1">MRLYVLLSFLLCLGVASAQMAMPITEAKGRGGRDKDKGKGGKGDKQPVRGGAAALQNQIADLRKRVAEANDTVVPFEGGSLKGLVGLLKVNEAIVTLGSTIDVSTKSAEATNTLPANESTQIGTQFLSLQPEINNLLTEVQGKRPEFDKAGFRILDVRSLIRDSVVIQKDKAGDLGGAVSQMSSFTKALDPTFQPIATQISDQIQGNFTAAIDEYDGRAGKIKIPSKAVPVLTDLLAGVARALGVGDRNKALAGPVTEAEAAAIPVTNFPNAEAAFADISAADTPEANIAAQEALRGNDDFSRLGPDENDLRGIPPLVLAVLRRYEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIZ0</accession>
    <name>A0AAD8UIZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_784420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362164.1">
        <property type="nucleotide sequence ID" value="XM_060515606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIZ0"/>
    <dbReference type="GeneID" id="85399504"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1721368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="501" mass="57274" checksum="784546C9F0EE7B5A" modified="2024-05-29" version="1">MTWFAAITVSGSLDDLIVKAVYLGFFYLVIKYTYRMFLSPIASFPGPRIAGITKLYEAYHVLLKNDWLENLVSLHEEYGPVVRIGPNELHFADNKFNLDHHRRPDLFKCNNYYGLLNKLLGGLASPTKHAQRAAVMRPIFSGQTLAEYSKTLDKHIESLHSRLADAASDKGVINLTHYLWAYTNDVMISYLTEENYGFQKVYDLQATHDATRAFSAIDLATVLRCMPPVKIMFDYVPALRSFSPLGWLDNLISSHVRPMVKSWDDENSHQSVLARVFNEIGNETQTVHESSQAIFIGNESLLSNLTFVLHHLIQNPECIKKIRAELDTLDIGTYGHRIWRDPKTAQLRYLDAVCRESSRLSSPSWHRQPRQSDTPVEYQGAIIPPMTSMSFTLHLLERDATLFPDPNAFKPERWLGFNQESKTTKGHSVSFGTGTRTCLGQHIAHRVLRKTVAFLIYNFNISLWNEKMDRADGFRYLNTYPKKGHEGYMKVQMTPRFGSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJI6</accession>
    <name>A0AAD8UJI6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Quinate dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_619784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Aromatic compound metabolism; 3,4-dihydroxybenzoate biosynthesis; 3-dehydroquinate from D-quinate (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.24" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365562.1">
        <property type="nucleotide sequence ID" value="XM_060508151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJI6"/>
    <dbReference type="GeneID" id="85392050"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030266">
        <property type="term" value="F:quinate 3-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01065">
        <property type="entry name" value="NAD_bind_Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000610">
        <property type="entry name" value="Quinate 5-dehydrogenase QutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089:SF1">
        <property type="entry name" value="BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="SHIKIMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0672">Quinate metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate dehydrogenase substrate binding N-terminal" evidence="7">
        <location>
            <begin position="27"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00071171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="35517" checksum="E7C6783861B11F08" modified="2024-05-29" version="1">MASATPIDQVEDTIAVKIEQLDRHGYLFGQKITHSLSPLLHTTIYEGIGLKWEQMRLDSADLPLFLELIKHPKFYGSSVTMPNKVAIIPHLDELTDECRDVGACNTLFIRERDGKRIYCGTNTDVIGVRESFVQNVTDPDAVYHNKPALVIGGGGAARSAVYALRKWMKATDIYLVNRDKSEVDAVIEECSARGYGDNLYHVSTVEEARDLEAPGAIVACVPNFTPKTAEEIVAREIIVEFLNKDRKGAILEMCYNPTPYTEIGALAEDAGWQVILGTEAMIYQGLEQDRYWTGKEVDELTVQKVKDVIAAKLSQHSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJM6</accession>
    <name>A0AAD8UJM6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_579569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364052.1">
        <property type="nucleotide sequence ID" value="XM_060505255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJM6"/>
    <dbReference type="GeneID" id="85389154"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF125">
        <property type="entry name" value="GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="410"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="718" mass="80512" checksum="EEDBA339FEBCA980" modified="2024-05-29" version="1">MGRKHAPQPLTLSESQASSDQPEDVPRSAETLASAVPPSAGSKSQSSPRSPRSPFRFTPKRPSASGKQSLQLTDEHRNFQDQDDDDDDLEQYQAISSALHRASEDTPPRQHHQHNPISPRQQQHRPNEPSRRPSKAAGFFFNFTKSANKSSHSLVSPAQSPSHPQRQHQQHQQSPIQYPDSRGESMSRGPDNAPPMSSQPTQPLDPSYAEHSVQKPAPTLPSRSDVSLASAADYDTSPAQPSSSKKSKSKPFGLLSRSKSLRDKDGSSSRDKQPSPVPVTIVEPEPSHTSTSRNHSLNNASTGPERSAREMVNSTGRNRSEDRASPREMSHRDNHREKDHHPRQNSSSQNGGFFGGLKSGRDIISNRLFGKGGRSGSTTEREPVIDDEHYTLKTINLPLVEQTRRTRISKRLEDSRDKTEFWMPAFPWRAIDYLNYKGCDVEGLYRVPGSGPQIKKWQRKFDEEYDVNLFEQPDLYDINIIGSMLKAWLRELPDELFPKAAQERVARECAGYETVPPLLVEELSNLSPFNYYLLFAITCHLSLLLAHSDKNKMDFRNLCICFQPCMKIDAFCFRFLVCDWRDCWKGCKNEAKFIEQEYQLFDQPPPKGLSEPRKPSRETSEEPAAPVAQEEHTPTTLDDRAGSSSESSKQSSAVTEQQTKEKDRRLKKKPLQLSESNGSVASNSTMGTTLTIDSGREPRGSNDLRPLSPIKPLSPLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK42</accession>
    <name>A0AAD8UK42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_719275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365446.1">
        <property type="nucleotide sequence ID" value="XM_060512161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK42"/>
    <dbReference type="GeneID" id="85396059"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="402" mass="44655" checksum="8061BE733E46CEF3" modified="2024-05-29" version="1">MEVITLLQGDEDSHLTPFFMCHAISGLALPFLRLEALSEDDERPVYGITSPMHCPGGDDFEFPETLRDLAALYVEKIKDVQPMGPYLLGGWSMGGMIAMNMAMVLRDQGEQVTKVIMLDSANPETFPSFPSAKDHRSLTHLTFTRTVAADIRLMDADCSPIGSPVISESEFGDYLTPSENRTSTWGTFTTEVSYSSSASSDYEGDSPAWSPSTPGSPACSSDAGSEYCPEQNRMLEDFPTEDQIDAEILTAAHDLEVAKHEDGEEDEEDEDADQDEEELDDNEPDQVRDFLQKIKKHIHKGLGLISTVEPGQLLPKNGVSDFHTVLIKCKPDPFDDPNLTQREREGVIFVRSVMREKAMCWEADKFVKFETVPFSGDHDGAFEPQHVGELSGIFRKCLQDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKX4</accession>
    <name>A0AAD8UKX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_577174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <dbReference type="ChEBI" id="CHEBI:34718"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:133977"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 glutathione + H2O2 = glutathione disulfide + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365233.1">
        <property type="nucleotide sequence ID" value="XM_060504993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKX4"/>
    <dbReference type="GeneID" id="85388892"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="17"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="11477" checksum="BF5D158D2F34CEED" modified="2024-05-29" version="1">MAATKQKVQSLIDDNKVVVFSKSYCPYCRATKSVLDEINADYTVLELDQIDDGSAIQDALHEITGQRTVPNSFIAQKHIGGNSDLQGLLKGGKLENLLKEAGALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULB1</accession>
    <name>A0AAD8ULB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spliceosomal protein DIB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_580840</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363486.1">
        <property type="nucleotide sequence ID" value="XM_060505392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULB1"/>
    <dbReference type="GeneID" id="85389291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR017199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16844" checksum="93DDD382A3940BD0" modified="2024-05-29" version="1">MGSIVIPHLNSGWHVDQAILSEEERLVVIRFGRDADRDCMKQDEVLYRISDRVKNFASIYVCDIDQVPDFNQMYELYDPCTIMFFFRNKHMMVDFGTGNNNKLNWVLEDKQELIDIIETVYRGAKKGRGLVVSPKDYSTRHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULE3</accession>
    <name>A0AAD8ULE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_319729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365042.1">
        <property type="nucleotide sequence ID" value="XM_060502364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULE3"/>
    <dbReference type="GeneID" id="85386263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="488" mass="51071" checksum="5E52C2F97321AB2D" modified="2024-05-29" version="1">MLTVWTRPPAEASIQVTTVTVVRTVTVELARGTEVIWAPLQQTLTFINPTLVFETTVVTALQSRDIAARAAANAIALDQAATLEIPSTETHYEEGAGLSSHPAPIRRQTSASVNRVSIITVEITTTIVASGTIVHTVTIFDPVFVSVTKTPTLTSTIFTTTTLPIEDGVSSSPAIAPSPPASQKAISSDGAQQTASSTSPEPSVAATTVAAPEPQEPPAASNTVGAPESSRIRSSSDTPRGTFISSSVRPDSSPATNEGISARVGPATSSSPSMRSTSTTAVPPLTETLLPPTERIARPSLSPGVIAGIAVGATILLTASILLFLCIRRHRPKRNRSLQLSEGDRYMTSAIAATAMMNQPTSNTLAYDGPYQVPQTEGSSGKSSEEEQVRIVIQPVIKKRSMSSVLSALPKVWPRPPGYTGKAYSFSAGGSGETTPREPVGWSVESEYGSSGNLDVSRSGGCEEAIASKGAARTHSKGDGRREKGWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNR9</accession>
    <name>A0AAD8UNR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_613726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367261.1">
        <property type="nucleotide sequence ID" value="XM_060507774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNR9"/>
    <dbReference type="GeneID" id="85391673"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="74" mass="8376" checksum="C9F2955DCDF08E6E" modified="2024-05-29" version="1">MRNLRNIRFGAWEQQQQQEVDPSAAVTACCWDPAKDELLCTTGPTEAKATIELVRLSDHHQQQQMCGAIFYLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP53</accession>
    <name>A0AAD8UP53_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_616292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366377.1">
        <property type="nucleotide sequence ID" value="XM_060507963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP53"/>
    <dbReference type="GeneID" id="85391862"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="56" mass="6729" checksum="7A2B07BCB452CB2B" modified="2024-05-29" version="1" fragment="single">MLGWRLFQQGQNHLCFKSWEEKRFRRVSKRQSFADQGGPSKPWNLWTFGLSDDKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPE3</accession>
    <name>A0AAD8UPE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365016.1">
        <property type="nucleotide sequence ID" value="XM_060514153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPE3"/>
    <dbReference type="GeneID" id="85398051"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="65" mass="7039" checksum="F48894B5DCC6C9B9" modified="2024-05-29" version="1">MPEGRQSPSPERQTGAQLQDPPASGKGTDNASNKEQTNKESLDKLESNPKGPLDDALKEKFSKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPU0</accession>
    <name>A0AAD8UPU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lactose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_698073</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365583.1">
        <property type="nucleotide sequence ID" value="XM_060511390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPU0"/>
    <dbReference type="GeneID" id="85395288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="61"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="539" mass="59769" checksum="6E3C445510642397" modified="2024-05-29" version="1">MNFLRQRLPAPRQDQQARQARQQGGPAAASESYQPSRIAQLAQESPIWYKSAARRKLYFLLFPAAVVSYATSGYDGSMMNSLQTVSYFDDFFDNPRGAVLGLMSAIMALGSICSTPIAPWVADKFGRRWGITTGSCIMIIGAILQCESTAFAMFVVSRFILGFGLSFATTSAPSLVSELSHPKDRVTITAICNTCWYVGSIAAAWITYGTRNIPSTWSWRIPSLLQMAPSVVQLAAIWFVPESPRWLISHDRGDEAMEALKQYHGEGEETELVRLEFEEIRAAIDNEKRLGSTTWASMVKTKGNRYRMFLVICMGFFSQWSGNGLIAYYLSRIMDTVGITNKNTQALVNGLLNIWNFGLALTTAFFVERIGRRPLFRISTCGMLVVFIGWTIASARFAETSASSAGIAVMALIFIYQVFYCIAFSPLPVAYSVEVLPYSIRAKGMATYVFSTKAAVFVNQYVNPIGIQNIGWRFYIVYVAILAVEACIAYGWFLETKGKALEEIAVIFDGEEANVRIAENGKGHGPIEVEETEHATSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ72</accession>
    <name>A0AAD8UQ72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_169122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368011.1">
        <property type="nucleotide sequence ID" value="XM_060501452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ72"/>
    <dbReference type="GeneID" id="85385351"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="53035" checksum="6E0DEBD1624028FC" modified="2024-05-29" version="1">MSSAESERSAPALDKVVEEQQLLWNDNDVPAEDSDAFVSRIHRHFGEHDAKNETFQLKDDQISNWFNPPNPECHASFGDCGVTATVNAYGDLMQFSSFLGAGQSGVFSADHSNIDEPFYVRSRAEQLLEMQRDQVRESDGYGLRFPSINPQRCRNLGYVHDRWPRYEMEHDKVKLTLQWMVHERTVLQQCLITNDRADDVEVPFRFAKAMHIRDLDYLQWPDPEKQPGHFQRQAPNGYGWVFVQHLQHDGADREKNNEAEPTLMPSVATQIETAGEDPKEVSKHAELPSPEPLDAVAVVVSVFVDGKAVHWGHSDSTITGLWTRSLGSKATVEVVAAYKMVHLTKSNAAWDEFLIPAVRADVGKYLKSVQFTAFHISKYIKPAEDKKTEKPEKSRIRWVQSVLSTKDTQPHRLPTNSSTDHIDFVVRRNLENILSACAIPVENPSVEGGTVAVALTCGDMSMHRVCSSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQK2</accession>
    <name>A0AAD8UQK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_622097</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364700.1">
        <property type="nucleotide sequence ID" value="XM_060508309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQK2"/>
    <dbReference type="GeneID" id="85392208"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042073709" description="DOMON domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="10">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="466" mass="51640" checksum="13EDFDCB9E552DAC" modified="2024-05-29" version="1">MLFSTLGRAALAAAAFATCSFAQSSKDDDLGQSTFVAPENNVAFGFTVPENSGEDIFFTMRAPIDRTWAAIGIGQDQMAGSLIFMIYRDETGNNVTFSPRIAYGNYEPTYYNNMQWDVLAGTGVFNNSMYFSARCTAHCRSWVGGWIDVSNENQKAIYAVGPKGSFFSNKQDTSVKFHEEFGRFTLNMKRTVGPGDAPVLKDSSVNEGTTQVSANDGRRDYKSIFHAVLMVGSLVFLIPFGAILLRFGNMVRWHALNQGVALVIVLIGFVLGVLTSFWYSRSRGFKSAHQIIGFIVVGFLLGQFAIGFLHHQKYKKTQRDTPYKVVHQWLGRITIALGTFNAFLGFSFALNRRFNYFLAAFIILMLLVSLFFTFGGKWVRGRLPAKFGNQATGGYNPEPWRQAPPQGGYAYTGAAPPAYQPPSHQNQSVGLTSMVADPTQPTKERSGSRDYRNNDLGSAHQPREMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQX0</accession>
    <name>A0AAD8UQX0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_289233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365781.1">
        <property type="nucleotide sequence ID" value="XM_060502177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQX0"/>
    <dbReference type="GeneID" id="85386076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052358">
        <property type="entry name" value="Aro_Compnd_Degr_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35563:SF2">
        <property type="entry name" value="BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="1">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="35333" checksum="1A8B16B2E0D7CC0E" modified="2024-05-29" version="1">MESSKFTPARSSLSPDSWDTHVHVFDASIGPFEPGRSYTPARATAQQLLDFSSSLTQATPLNIVLVQPSPYGSDNTVLLRSMKSLREGGSRIVRGIAVVDIENISDADLMELHDAGVRGLRINKQADGKSTDLEALKEIILQTASRIQYLPGWKIQLFCAPAMWKDLYETIITLPVQVIADHVGGMRAQSKLQLNAATSSLNDPTKQPGFEALVKLAKASKVIVKLSGFYRLSDRTESGCDDMESIVKALVKAVPHRLVWGSDWPHTGEGKDRLNRGLEAVEEFREIDDARIIQNLRRWVEDEKAWMGLMVENPAGFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URV4</accession>
    <name>A0AAD8URV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_224182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367320.1">
        <property type="nucleotide sequence ID" value="XM_060501760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URV4"/>
    <dbReference type="GeneID" id="85385659"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="134" mass="14775" checksum="BAED678DF6C4F0A8" modified="2024-05-29" version="1">MAIEKRGGEGISELVDRRADFPRVSAEYGIWKTIQNSSPSSFNQDPSTSILQVTWDDSQTQNVFCHPRTSPAAKVQSRYLSKPPLRPRLTSHCGPEPGVFVTLHANAAAHAYFVADSQIVHSMRALKVGVEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USJ2</accession>
    <name>A0AAD8USJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366576.1">
        <property type="nucleotide sequence ID" value="XM_060504710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USJ2"/>
    <dbReference type="GeneID" id="85388609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11370">
        <property type="entry name" value="RNase_PH_RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000024">
        <property type="entry name" value="Similar to exosome complex exonuclease RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="2">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="28620" checksum="6D0C5F3BEED0EE5B" modified="2024-05-29" version="1">MPLDTSTYSMALLRVDGRRWNELRRLHAQIRTQEAADGSSYLEMGHTKVMCVVTGPAEPQRRGGAGGQSKEAAVTVNLVVAGFSSVDRMKRGRNDKRSQELEATIAKAVSANLHTHLFPHSSITISLHVLSQDGSLLAALLNASTLALIDAGIPMTDYIAACTAGSTSTYAAADDGADPLLDLNTQEEQELPYMTVGTLGLTDRVAVLVCESRVQVSRLEGMLAVGVDGCKQVRQFMDRVVKEKGRQMVQEGTVEKGTGLDLEMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UX66</accession>
    <name>A0AAD8UX66_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_610889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368060.1">
        <property type="nucleotide sequence ID" value="XM_060507620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UX66"/>
    <dbReference type="GeneID" id="85391519"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="56" mass="6430" checksum="C061ECD6563984F2" modified="2024-05-29" version="1">MPWLTPRPQRNIHCYRIPPLSFMKPLQQSVCLISTSLRSHRSLAVKSIYLFTSGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9T0</accession>
    <name>A0AAD8X9T0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_154598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000192">
        <property type="protein sequence ID" value="KAK1708679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358361.1">
        <property type="nucleotide sequence ID" value="XM_060501348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9T0"/>
    <dbReference type="GeneID" id="85385247"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="320" mass="35899" checksum="A3F6D14276A08FC4" modified="2024-05-29" version="1">MQSQRRRSTDVPKAARQRRLSNQSITLTDSWHFFTPAAEAQGAFSSNVYCLLHRHRQRWSWSSTYAFAPHVHTRARSHQPLRNWRGIQLSINGDDDKHRSRGEGGKLGATVHRDLRRTLVARPRNVCVPLAIPGTEYNQRMAATWQRIGNKAVLVGSNRICGSFGPKRFNTAGIATSLAHSPYSSLEPVALLRLLRSTQYVSGSQLASRPSESWPCVLGKEKGTWGQKKEAGRYTRDQSSPTWLIKAPTDIYQIYGYPGRTIEANLTNDRQERPASHLPSAVLASESIPVPCLSDTRFVINHGREHGWTMPSPPSQLDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA33</accession>
    <name>A0AAD8XA33_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 oxidoreductase OrdA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_714616</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000332">
        <property type="protein sequence ID" value="KAK1701860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357069.1">
        <property type="nucleotide sequence ID" value="XM_060511661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA33"/>
    <dbReference type="GeneID" id="85395559"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1701860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="57351" checksum="0EB743C836E9D4F0" modified="2024-05-29" version="1">MFGVSLIYSGAIVLLGYIIFNRIQQRTRGPLPPGPKGLPLLGNILDLPLSETLEWVHWQKHREQYGPITSVSVLGQLFVILHDKQAVLDMLETRALKSASRPKLVFAGELVGYGDIMGMMPYNRKFRLHRKLTATQVSKKSIVRFETIQERETLRFLKQIYEDSDSNSDTLQGHLNQFAGSIMLQILYNYKTDGKNDPIVAMSKQVMEDFSKATSPGAWIVDLIPWLRYIPTWVPGAGFKKTAEIYRQHLLQGIDVPYDYVKEQMANGNDDVSYVAGLIKDLHRKIDPEEKNVIGWTAASMLNAGTDTTGAMLYSIFAALVLYPEVQKRAQDEIDRVVGNSCLPSFSDKDSLPYVQAIAQEALRWHTLAPMGFPHLTTEDDTYNGYFIPKDTLLFPAAASLMHDPDTYHDPMEFKPERYFEPFNEAPPTDVVYGFGRRACPGRYIAEQTMFLCIAQVLAVFNVGRAVDEDGKEIEVGYEQLPGVIARVKPFPHRIVVRSGKHRRFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAM6</accession>
    <name>A0AAD8XAM6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_708394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360277.1">
        <property type="nucleotide sequence ID" value="XM_060511559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAM6"/>
    <dbReference type="GeneID" id="85395457"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1715478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="240" mass="27051" checksum="7C6151E8EA47FB38" modified="2024-05-29" version="1">MLATSQSQHATKTFCGEHHIIDWKFELRDISLHNSCIVGGLCALAEEQFCPKTSLFAAYQRSGLWDACDPEHRACHIDEPCMVTGEKSCARILYVAKYEHANGTCSARGPDHVFCPTISDLDQQYLFPECSACLILTEARGLVLIHRRMLDECVEDEGLSSTDIDCIRTSLSGYIRAYNVRRKLHLEELQKVVQMKHDLEMDYASGNGEISRAQSHATGRKGWWKSVVERAMNAVIRILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBB9</accession>
    <name>A0AAD8XBB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_681012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360041.1">
        <property type="nucleotide sequence ID" value="XM_060511209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBB9"/>
    <dbReference type="GeneID" id="85395108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1714579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="33603" checksum="397476E9337CCFA3" modified="2024-05-29" version="1">MLVLIAGISGSLGSRLAVVAKEHGLSVRGLGRDSSKLSPELAQSLESFVTSRNYYDIPALDKAVAGVDAIICAYNPTPLLDLDGCLLLLRAAERANVKVFMASSWNNDWTKIKFGDFEHYDAHIAFEQQAAMTSSINPVYLFTGIFADLLFTPYGPGGFDTSGDVPLMRYWGEGNKKLHSWTAQDDVAAWTIDILINGDGVQQGKGGFFRMRSGVNTIEELALAYEEATGTFVEVKRQGTLGMLAEEIARLRKEKGRARNFEYLPEVVAFLSDQGLFEVPASEIVSMGHVRKPTTLEEHLKIRFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCH2</accession>
    <name>A0AAD8XCH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361286.1">
        <property type="nucleotide sequence ID" value="XM_060512463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCH2"/>
    <dbReference type="GeneID" id="85396361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="181" mass="21030" checksum="2E3C6E7A474B9FB1" modified="2024-05-29" version="1">MTSEEWSQNEITTSQFLYGDRFNPNNICSNCGHAGHWLGDCVFPDDNGTIMGCPIHNTKLHVLDDCPDLPHMSLQQRVTTIVVRRRNKPAIRSRKPWIELVKEAMGQGLEELVWAPSVWTQEFVLRMIHDRKSLQPWLDFDYGRDLVSKLPVDPETQGDLRSLLRKCSLWEQVHRPVRQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD34</accession>
    <name>A0AAD8XD34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Integral membrane protein S linking to the trans Golgi network-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_588015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360308.1">
        <property type="nucleotide sequence ID" value="XM_060506092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD34"/>
    <dbReference type="GeneID" id="85389991"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="166"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1715509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="22769" checksum="785FF6F98C202EDC" modified="2024-05-29" version="1">MPRRRKPPRPGALNDLPPLRIASQIAALQGLYYAGALVLMLFSALVAGTGFTLDLVFGWEAVRGDTTQGWLGAFLWVLDGGFCMAVAIIILIGRSKLVPDFALTMHGLHLVVTSLYTGRIPRNAMWWGAMAASSGICVALAVWGSRYRELRPISFGGGGGGNIGGGAGSSGDGAAQNGGTGDEEDGLGFSRGRGRGRGRDGEGGYEMVGMDHERRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD86</accession>
    <name>A0AAD8XD86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-binding monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_754708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362036.1">
        <property type="nucleotide sequence ID" value="XM_060514511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD86"/>
    <dbReference type="GeneID" id="85398409"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050631">
        <property type="entry name" value="PheA/TfdB_FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476">
        <property type="entry name" value="3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43476:SF4">
        <property type="entry name" value="BLR0106 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1721240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="435" mass="47982" checksum="D27E3A4E692205AB" modified="2024-05-29" version="1">MGSIPLNPDVLVVGAGPVGLFAALRLAKAGVSVTILEKDSGLSQLPRACMFYPQPQFALAETGIWDAIIKGGGFRSTGLDIRLPPISDEEGGKKPGKIVGSFPKDPKHDPTGLPVRPPAISMLNMAQPELTKVLMEKATETGRVQILFNKELVSILNDGNNGSETVAIAVKDLHTGQIEEHVASFLVGSDGGRSKTRSLLGISFPGHTWPEKLIATDVWLQNTEESPVTTTLLMEPVHYTIITPLTPPVKGEVTKWRLTFAVDPEELKTKTEKDLLSEEYISYHYERAWAGPRPLTYKIDRAATYTIHQRLASNLRRGRCLLAGDAAHVNNVIGGLGLSNCLMESVALSDALILILKEGKPVDTVLTMYSDERRQVFQFFIDPVSSWSKLRIQAGEQDDWFFRCLSDTSSPSFARWVDMMENFWPTRIREMAKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE43</accession>
    <name>A0AAD8XE43_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_623108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364464.1">
        <property type="nucleotide sequence ID" value="XM_060508365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE43"/>
    <dbReference type="GeneID" id="85392264"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="40"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="689" mass="76714" checksum="74DA94216B473000" modified="2024-05-29" version="1">MSDIQPTEETPVHTRRRRRERPMLVCLECHRRKLKCNKQRPCDRCSKNNPPLKCTYVRPVLGTASKRSPREQQQQQASNEREQGPDIRHTPGHSGDPADARPETILSAGNRSASVTESRDRSVEADDADSPNPGPQEGLLGGNADALGMSENAGTPTVKPSKLNSRRTWYGRSSNHWLFPKFQHIMALMGRAGFSLPGGHFTTFNELKTSLYQRRTLFLGEAQGPQLSMFEEFPTRLTADFLIRQYFDTFGSVFALLQKPIFQDQVLMFWEKPESVPISDCIQILLVIAIGNGTLDTNSGRLPDTKIEGWWHLILAWQSVALRSTPCDVGTLQACCLIDIMRQVYSLDSTATWSSSGMLARNAMVAGLHRDPSITGDPLTKDELETQQNLWYTILELDLQSSMNEGLLTTIGPDDWDMSLPAPPKSNGMGEGYNLDASSPVRYLISTLRTRMRIANFLNDIRCSVKYEEASKLQETFEAVARPLLANSSPDRGNFALHFSTVLCQRSLLALHLPFGVQRSSSLAFSYTLCVSTAISILETIDPPNKLAKGYDLGGLVNMMRTSGSLFRTVALQAVLFLCFQMEASITDNKPWTLIAELRDRIIDIVDRYALIAERRLATQDFVGKAFIIANMVSAKAKLVRMGHSGTEIDAASPAMAKDIAEVCFAIFRNRPDIPGPVQEDMTPMSLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE61</accession>
    <name>A0AAD8XE61_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myocyte-specific enhancer factor 2d</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_349981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364524.1">
        <property type="nucleotide sequence ID" value="XM_060502516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE61"/>
    <dbReference type="GeneID" id="85386415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54399" checksum="32EC5F7AC42FB9FC" modified="2024-05-29" version="1">MAPQPRMQIPGYYYDEEKGKYFKIEKGASAPQTAAWSADNVKRRKIQHREAEAVAARRERLKRHIVRSAALRAPLIGGVLDVELGVRREERARLRVDGAFGVEDVPAAAWARGLVDKGEVPFVPSFARQSFPNIPCFYVGGDDEKTGLGVAYATLDEETLIGSYIPTDDNERISFSTDASSRPERRLSHRHEMIGCPQISSINYHPHSHRIIVTSREPSNTCDIYLFSPPKSARNDDRPLWLLDRANNLRHISFNTGRREGVVNQTTPAPPSSSSLTCIIGTSYGLLKLTSDERIHWLGPPRPRPGPAEGYFFDQTFLPSNPNVLLAGGRNRDVRLIDLRVKWSEWDNIPVGATAHLRAVNPHQFLAAGPRSKMALFDLRYRKAKPNGTKPVVEFPGFRNEAHMHFGWDVNVDSGVVAAAHDDGRLGLYSLLSGRRLRCPAVDAVKARTPVKSCQFQKMPGRRHASLFAGVGPNLKMFSVGALGVDEEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE82</accession>
    <name>A0AAD8XE82_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_578592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364584.1">
        <property type="nucleotide sequence ID" value="XM_060505144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE82"/>
    <dbReference type="GeneID" id="85389043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40826" checksum="70CA066FA7C46CED" modified="2024-05-29" version="1">MTASNPPPKILLSGATGYVGGSVLHYLLKHPSLTSIITSSSPITVPVRGTPDRVKKLTDSYGSLVKPVSIASYDDTLALTALASEHDIIINAGSGFHPPSAEAFVHGLAKRKDRNGGRPVWIIHTSGASNIADKPLTGVNRPDAEYEDAFAEKVYEFEEAEDVKDPYPQRTAELAVLRAGEELGVNAVSIQSPCIFGPGAGLFNKAGLMIPIMTGYVLKNGCGLTLGDETGCIDYVHVSDLADLYVLCVLDIIDRGGVNVPKGKKGIMFPTVGRTLTIDIPRKCLDIAFATGNLPKKGGPREKIVRNVSLEEAAETCAGNKDVTETGYAGHRKTKGTVAREQLGWKPIYGEEAWCKDFETELRAALNGQRPYTMGNCIAGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEV3</accession>
    <name>A0AAD8XEV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_384058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363806.1">
        <property type="nucleotide sequence ID" value="XM_060502730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEV3"/>
    <dbReference type="GeneID" id="85386629"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36024" checksum="EA7CE887ACCBA70D" modified="2024-05-29" version="1">MGRVKSEQPTGKKAQANGRDQRGRGGRGRGRVQQDRTHRIPEPWSARDDYALGRLHSPVPAPAPEPWVSMGDLDRNLQTWMREGQRDEILSRWGLGPGEYDILEDRVLADIVAKWPDATVALLYDKAQEAKEHVYRHFAGQGKVRISLEASDWLKLEGLWKLMDKAHSHEERKYVFDYTYGQIRFFDRGLMDKQYAFYFKKYEHKRPRAQDVAPAAAAAAAPIAARPMSVPPAAAGTYLIREQAHMPAACMAAPGGPPPTAQGGGGCSTGNHGPGSFVPMHSQGPCMMGGGGGMGQPVVHGGTAGHFYPAPQHHHHHPGAQPGPGMGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEZ1</accession>
    <name>A0AAD8XEZ1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_621860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364822.1">
        <property type="nucleotide sequence ID" value="XM_060508292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEZ1"/>
    <dbReference type="GeneID" id="85392191"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO/CreE_NAD-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent urate hydroxylase HpyO/Asp monooxygenase CreE-like FAD/NAD(P)-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="504" mass="56185" checksum="184D31B88A437A3D" modified="2024-05-29" version="1">MGAVKRVAVIGAGPAGAITIDALAREKTFNVIRVFERREAAGGCWVGDQTPPPHLTNLSSLAARTADQPLQIPETLPSRTPKAPAGSASAPAPPRFTESGIYPYLETNVDAIPMSFSEESLPEQRTENSIALHGPETPFRHWTVVRDFVQGLVNRNGYQDFVSYRTTVERAEKAGDEWKLTLRKEGDEWDDWWVEYFDAVVVATGHYWVPYVPYIEGLEEFERDRPGSVIHSKHFRGRDHFRNKRVVVVGASVSGADISVDLVKAAKLPVYSVVNGRKANLYFGDGAFNHPQISRRATITHIDPATRTVHFQDGTSVPGVDSIVLATGFTWTLPFLPSVELRNNRVAGLYQHVIYHADPTLLFIGAVAAGLTFKIFEWQAVLAARVLAGRARLPPKEEQARWEAERVKEKGDDIRFSLVHPHFEEYFETVRELAGEPEGEVGRALPVYDPSWFRVFMDGLELRKKMWVRLNAEARDELQAANGAGKEGEKGPVVTTIEAPQEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFD5</accession>
    <name>A0AAD8XFD5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_412391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362828.1">
        <property type="nucleotide sequence ID" value="XM_060502922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFD5"/>
    <dbReference type="GeneID" id="85386821"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF17">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="622"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="79733" checksum="837DDD4930BF7124" modified="2024-05-29" version="1">MTETTPSSRTTTPPPFSDVVLIIGRACNSKRKGLDKALYQIEQAIKRARTGEHNSEDDKAIGSLQALLEGSRNARSTTASSHLRRGSSHFNSPDQPDLSSDDDDDLDNTPDSNTYMSLHHHNEESLAIDDAENPLQLLARASNLQLSPKPISGLSPKQPGPRAGRKKQVEQPDEDLEIQSFFTSVRVNFDVGDDIDPIIMGLVTEEEAESLFAFFHGKLAHTRWGLDPKIYTPSFTRSRSAFLCTSIMAASALFLPSAGALSKRLSNHCKTLAHRVIANRHKSVEIVLAFMVNVPWMFPGQHSTDDETCWYVNMAATIAIDLSLNKLLIPMEVVGSGSNMALSRGDCLDPRTALAMDGFSHIEHTSDLGQRLLRRRERCWIALFVLERGMSLARGRPYTVPITRVIKDCDQWHRSSIADPMDGHLVSMAVLRRDLDGLLNTVRALCDGSQGISTDGGLIAQSIQSAIERFFDQWLTEWGYAIGTGPQRRLPPYVEILVTHTRLSTYGGVINHPTAPMEVRQFFRTAGLSSAVTVMRAAIQGESQLQSIPNNTTIMVSFAACFALTLSAYATGSSNLAPSIRNLIEETADVLERIGSATKHRNGLSTLYGKYLKRIVKKAATAMDGQPQTSLHPDPTIPRSGQLGTPSSAVAASPPVNMGPPVSQPPYMESQLWPGTLQFSAMSDDQIAEVLNQPGNEFDPSFAGLSWDDMNNFDWLSWPNLTEFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFG8</accession>
    <name>A0AAD8XFG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_549088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364376.1">
        <property type="nucleotide sequence ID" value="XM_060503473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFG8"/>
    <dbReference type="GeneID" id="85387372"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="29232" checksum="77308F04768AB946" modified="2024-05-29" version="1" fragment="single">MSRYYEHEIREDRPRSPSHHRRDDPPPVTREYSPEYYSGGGAGSIQVVYPDRGPVPIASGPYISGAIPVDAPPPFHPYYPPESPLSPRDSNALQLPPQSHYRPRSLPPQAYAVGRPRSRSRPQSPIGKARHAVDHAFTQSSSGIGVGLLGAVVGGLAAREVSDATVRSRTRKEMENGTYRPRSPREAEKARVISTVVGALVGGLGANAIERRFEAARERDREQQLAWERKWGRGRDHDVDHGRGRLRNRYRDEWNDGYPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFM5</accession>
    <name>A0AAD8XFM5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_718814</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366099.1">
        <property type="nucleotide sequence ID" value="XM_060512115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFM5"/>
    <dbReference type="GeneID" id="85396013"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29815" checksum="9D47BE127EBC7217" modified="2024-05-29" version="1">MVPKIQKVAVAGGIFPDGVNVKVVDFTSFDAIKDALQGHQAFVDCTLVHDDTPTRLIDAAAAARVYRFIPSDFSLDFDNRNVHSVPVFFKKDMNDKHLLKKCEETGMTWSVICNGAFLDWNLRTGFMNIDIYNKKNVHVWTTLESTGKAVSGALLHPVETENKPVYVHSVNKSQKQMVDLCKEALGTDVWTESKSNMDQVFAGALKEFQAGNHSMKVFGDMIRYANSRPDFSCPWPKDDNPMLGVKEMSDDEVKSLIKSIATEKAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG03</accession>
    <name>A0AAD8XG03_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZW10 C-terminal helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_615437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366594.1">
        <property type="nucleotide sequence ID" value="XM_060507895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG03"/>
    <dbReference type="GeneID" id="85391794"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="2">
        <location>
            <begin position="695"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="858" mass="95505" checksum="B9AC1E3C6075D15A" modified="2024-05-29" version="1">MAVETDQNASAQLGEAVVAFALEGRFPDEQVSSLSLSSSDLSPAIDALERAKGDLESEIHTINEETKGDVSSWVHNAKTLQEDILRSKRLADDIVRQSEAPQVSGKAIQDAEDHIQFLEKEVLYTNQLHDALRGIQHVNELLGEVEQAMNERRIIDSLRWLEKSWTELDAVPVNKKACRIMRLLDVRAFELKSHVHDVFDHVWASLVHTDLEAGSLAIYKKLDDEQMTLSEAIIGLQAYKEVEDRMSKLWHDVDKAIVFPRMDTQASSLPSIRETENVVELNGRAGRSIDELFTDLQKVVEFLAKRLTPDLLMFFSPIMMSDLVPRLISVWLDSEVPSNLKDLGRFQAVIESARRFCEVLEDNGFTGFTELKEWVGSAPSIWLAKCRETALDSVRVQMSNGLGATKQVEKVEKQMVSRSEGKELTANGVAGTVAEDDWGAEWGVDDDEEPSEAKDDTQEEDDGADAWGWNDEEQTTESTQEETAQAEEKTADDEDDAADAWGWGDDDATEQTEPEPKPQAPKAHTKRQKTVSAEPDESREMVLKETYHISSMPEPVLELILALLEDGAALTQPEYESSPVAAAAPGLFSLPTFALAMFRAVSPHYYSLDIGGNMFLYNDAMYLSEKLADLASKWKSREDLTTRAQNMLRIDNDIKSLQNFATRAYTNELGLQKTVLRDLLGGDQSLMQQDELDSCVDSALARVRSMAVTWESILARSVWYQAVGSLLDGLSSKIIGDVMDASSIGQDDAYGIAKLIAKVTELDDLFLPSRTTGATGAAAADEIPTTAQYAATWLRLKYLSEVLQSNLNEVKYLWCDSELSLYFSADEVVDLIEASFDANPRMRETIRAIRETPSPVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG13</accession>
    <name>A0AAD8XG13_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363473.1">
        <property type="nucleotide sequence ID" value="XM_060510584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG13"/>
    <dbReference type="GeneID" id="85394483"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="772" mass="83857" checksum="C6AE95E64CCB7EB3" modified="2024-05-29" version="1">MGFLRFFSSKRSSDKSSNGIKAQAYDATTASLPPLLGTYPVAGNGPTNVFEDLQRSHHKMSETNLSLAAGSEASAPAPPVLRFRDSSLERPSSAPGSAAPPSFSPSPPGRWGRDSSRGPPLSFRKPRLGSLTSTTSGLSGLSPAPKRNSNSPAIPFEGDPFRPPTAPFTHNRHLSMQSTSTAAVRGFIDLLDAQSEIKPSGFQSRVKASGARDYGEDVADRNIGENGVDLESDKVQAFYATNGGSPRDRHNGAFAAPARAQFGDKEQTFKPPRRHDSLDNEARTKSLTSASLGQVPFRTNMFNPESSLSREPIMESVSETIRGRRRQSLGAYIPTTPSNTTNGRTLSLRKSTADASGSPSARQHKRRSTLGGEAPLNELGIFTPGGGHPDPSLSPKMSQKPTYLVKHNYSLPVQQRPKTSSGLVHTESYQAFLPSILYRLLLFTPGRSSANTTCLTDVMRSGHSWLEAPDDSYLRSKSNGAPFGKGKLDEIYEHVPMRTSSLRHWSISSATPTMSSTSSFQRPHSRHTTTTTVDLATMSSFLNDSCSSLHSGTGDHASFCTALESALPSPITPAKPGDAFNIDDYLSSDDDIDADSFITTRKRDSAHSGGHEEGLLFSDEGYGEGGLQLPGLFDSLSNIPDPDTTSPERFGHKYSLSNPSGRLHRRFSLDPRIEAPMSTFDEGDNDAEDEDDGLYDIPMRSDLALGRRGTRRISALGTMYQSIEEEKDEKVDVRAAVRLRKEDKARQRALARFSRVQHKRVSQFEVKQGGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGK1</accession>
    <name>A0AAD8XGK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cupredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_721296</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass type I membrane protein</topology>
            <orientation evidence="7">Extracellular side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362635.1">
        <property type="nucleotide sequence ID" value="XM_060512375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGK1"/>
    <dbReference type="GeneID" id="85396273"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000022">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000024">
        <property type="entry name" value="FET5p Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042098150" evidence="10">
        <location>
            <begin position="20"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="530"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="13">
        <location>
            <begin position="28"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="179"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="12">
        <location>
            <begin position="341"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1722580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="590" mass="64662" checksum="2762C0B2DB34B79C" modified="2024-05-29" version="1">MVMTLSLALACLASRLAAAATVNYDFTVGWVTANPDGAFDRPVIGINGKWPIPQIEANIGDNIVINVHNDLGNQSTSLHFHGLFMNGTTHMDGPAQVSQCPIPPGSSFLYNFTITQPGTYWYHSHTMSQYPDGLRGSLIIHDPDNSYAGDYDEEIVLTLSDWYHEQMQNLIPPFMSKTNPTAGKTYLMRVINIGAFAGQYLWFEGHNMSIIEVDGVYTQQATAEMIYLSVAQRCSFLLTTKNSTAENFAIVGSMDTTLFDTLPDDLNWNVTGWLVYNESNSLPEPALIDELNPFDDMTLVPHDELARFGEPDQTVELNVIMDNLGDGANYAFFNNISYKAPVVPSLYTALTTGADAENAEVYGDYTHSFVLKKDQIVQIVVNNLDSGRHPFHLHGHHFQSLYRGEEESGTFADSNMTESDFPAVPMRRDTLVLWPDGNIVLRFKADNPGIWLFHCHIEWHVTSGLLATFVEAPLEIQKSLTLPQNHLDVCAAGNVPVAGNAAGNTKDLLDLNGQNAPPDPLPAGFTTKGIVAFVFSIISGVLGICVVCWYGMANHVSETNNPAATMLNVQESSGSATEGEIKRPAGSTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH72</accession>
    <name>A0AAD8XH72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_177231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367884.1">
        <property type="nucleotide sequence ID" value="XM_060501504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH72"/>
    <dbReference type="GeneID" id="85385403"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="31395" checksum="0CAD201E8D3750DD" modified="2024-05-29" version="1">MRAIRFEFEVRMTDDASRARAGQKTGRRRRRGTQNGMGQVTGFNCFGRAPASYPTPNPSSRQITNHGGASLLTRRTRQGSNHLDMELGAHWSLDSALCTGQTASIRTNLSPEVLHYLTLKGSPGVRIRMQSTNNISRRWTTWTNFLYWRPQPRYSMHPPIHDVQPCAGFCSSLQVVPRREVTGLTPWLCHPTPEPARYIEMRAVWSVELSSIAAPAWKMAAALRIGPSGCLNGAFLSLTGAWLSPLNIIAITRIGSRDVQPRPPGYRRPRATRSRDIPTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHL4</accession>
    <name>A0AAD8XHL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_749883</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367627.1">
        <property type="nucleotide sequence ID" value="XM_060513837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHL4"/>
    <dbReference type="GeneID" id="85397735"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00443">
        <property type="entry name" value="ADA_AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="39753" checksum="4E089B6E6269CDCB" modified="2024-05-29" version="1">MGSQPTIDMDFVALPKIELHAHLTGSISRRTLHDIWVIKHEAGGTDLEDPLVVMPDGKHDYDLTTFFPLFSSYIYNLITDVDTLRKATLSVLQDFQADGVTYLELRTTPRSLPSPTPQPPSVYVATILSAIDAFETSHRDNPNAMRTRLILSVDRRHTPSQAHETVRLAASFRNRGVVGVDLCGDPAARIHTAGQDDDNSETISIFRPAFAEARALGLDITIHFGEAECSGHPAELAEILSWSPRRLGHVIHLGEDVKREIAKRGIGLELCLSCNVHAGMVTGGFEGHHFGEWWGVEGSLISLGTDDVGVFGSPLSNEYRLVAEHFKLSRDEICALARRGIETIFADEAEKERLRQLMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHM1</accession>
    <name>A0AAD8XHM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_752025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365078.1">
        <property type="nucleotide sequence ID" value="XM_060514134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHM1"/>
    <dbReference type="GeneID" id="85398032"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="84" mass="9410" checksum="C810F165BB23AB8C" modified="2024-05-29" version="1">MPQSTGESKNTTDDMNMYPDDLTENNYDWALGPHERVGPDTGALKLSAASFDVKTSPDHMENIDVGHLSWLVSWFPYNAEHLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIF2</accession>
    <name>A0AAD8XIF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_749919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367676.1">
        <property type="nucleotide sequence ID" value="XM_060513842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIF2"/>
    <dbReference type="GeneID" id="85397740"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="124" mass="14194" checksum="05EBBAE47220E8D1" modified="2024-05-29" version="1">MANNGPSIKSEPGAPGSEAWDEERLERALDELKLLHVKLRGLRTTIPRMMEPLSVKQPSPQITFQAYMESVAAAKREVQDFQDLRKSDKITNIMEHATQRRKEEPNGIKAWRTTDHPDWTTTDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIT9</accession>
    <name>A0AAD8XIT9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1725010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365065.1">
        <property type="nucleotide sequence ID" value="XM_060514159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIT9"/>
    <dbReference type="GeneID" id="85398057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="50955" checksum="4160E7297AE7D2F4" modified="2024-05-29" version="1">MDAAKERNTKREDEDTTAKPSKISGLFPDWLIWYKKPEYRDFKEYATAIRTGRRPLSRDGRDKSPIPARLSLERVLNNQTCSPMSLYDFYMYLKYIEFSPENLEFFVWFRNYEGSYAKTGSLNNFPIEKDIDQSSSSRDSMADSAVDAAGTKLPSIQMSEFECDPEAANETMTNIVHLIAPEAACRPNSRVGPSGRDRIKSWANACAKPICANNVPAVIPTRIAPNSAYRIELNAVVNTFLVPGAEKELNIPPALRDTALLNLQHSSDPIHLKPIADHVYGLLKNCSHRNFVRLGVSNGTFETLCMATSVGIALTIGGFLCVLLKAFVPFMGANSRWNAFAPWPMWFVGMSLIFSGLRGSCFFLLLFTRRQPLPWERFDDSASLLSQRSGLMKFVSRMMIFDRKIRVKDVHLRRLQHKIVLQAMVGGAIFASLSTLIFIFLPVWSQTVVPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIY6</accession>
    <name>A0AAD8XIY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">ATP-dependent DNA helicase II subunit 2</fullName>
            <ecNumber evidence="4 19">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDZ83DRAFT_750392</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the ku80 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 19"/>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366938.1">
        <property type="nucleotide sequence ID" value="XM_060513911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIY6"/>
    <dbReference type="GeneID" id="85397809"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00873">
        <property type="entry name" value="KU80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000073">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1600.10:FF:000002">
        <property type="entry name" value="X-ray repair cross-complementing protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.240">
        <property type="entry name" value="Ku, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024193">
        <property type="entry name" value="Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036494">
        <property type="entry name" value="Ku_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014893">
        <property type="entry name" value="Ku_PK_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08785">
        <property type="entry name" value="Ku_PK_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016570">
        <property type="entry name" value="Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101420">
        <property type="entry name" value="C-terminal domain of Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14 19" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="VWFA" evidence="21">
        <location>
            <begin position="6"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR016570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1726883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="731" mass="80338" checksum="5FC7638D806994B5" modified="2024-05-29" version="1">MADKEASVYIVDLGSSMADCHNGRTESDLDWSMRYVWDKISTTVAASRKTWTVGVIGLKTDETQNAMGEEEGYGNISVLQELGPITMTSLRELTDAVKPSETDAGDAVSAVVLAVDMIETFTKKLKYKRRIYLITDGMSVIDGDDVDSIAKKINHDGIELIVLGVDFDDAEFGFKEEDKPSIKKKNEETLRDFVSKCDNAQFATIAEAIDELDTPRLKPVKPYKTYDGPLTLGLADPPEDLKIPPTPAVINVERYFKTKQAKAPTASTVVVSAEPGPSQQLEGGDPMEGVESTSAGFAAVKSARAYKINDPDAPGGKRDVEFESLAKGYQYGRTAVAISESEWNVTKLETVKTFSIIGFIPCEKYEPFLNMGETCVTVARKFDEKSQLALSSLIHALYELESYAVARLVVKEKKDPVLVLLAPRIEPDMECLYDVPLPFAEDVRGYQFPPLDKVITVSGQKITTNHRLLPGDELTDAMSDYVDSMDLGTFGTDDDGNPSEYAAIDDTYNPIIHRINQAIRQRAVNPEGEIDPIPPILVRYAAPPEDLVEKSKSQIEGLISAAQVKKVPPKAKGKRKFEAAKPLSGLDVDALLGTTSKSASKRPKITPENAIPDLKRALATAEDESEIRDAAKQMAAVVAQLVTDSFGDNNYARASENLSVLRRGLVELEEPGVYNDLIRDLKKKMLSGELGGDRREMWWRVRTSRLGLIDQGTSEVSNVKSEEADEFLKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ26</accession>
    <name>A0AAD8XJ26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhamnolipids biosynthesis 3-oxoacyl-reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_698329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365500.1">
        <property type="nucleotide sequence ID" value="XM_060511395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ26"/>
    <dbReference type="GeneID" id="85395293"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF3">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="283" mass="29502" checksum="B215640BC110E5DE" modified="2024-05-29" version="1">MSELKDFGSTFSLEGKTALVTGGSRGLGLHMATAFLLSGCSHVIITARKLEGEQGISQAIERLNRLPNTRGKAIGIAANVADSNNIVRLVGEVKDIVGEKGLNILVCNAGAAWGSKFEDAPPSSSIKILDLNVRGVFELVQKFLPLLEKAASEDDPARVLTVSSTAGGNVPHVGEHGTIMYAASKAAANHLGRNFAVELGPKNITSNIIAPGFFPSKLAQGLIDNLGGIEELSRGNPLGRLGEPEDLAGVAVFLCSRAAKYVNGVVIEIDGGARLVAGRQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ30</accession>
    <name>A0AAD8XJ30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_748877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368816.1">
        <property type="nucleotide sequence ID" value="XM_060513682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ30"/>
    <dbReference type="GeneID" id="85397580"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050362">
        <property type="entry name" value="Cation-dep_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509:SF14">
        <property type="entry name" value="CAFFEOYL-COA O-METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509">
        <property type="entry name" value="O-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="27809" checksum="FBA181F252A804C2" modified="2024-05-29" version="1">MKSSVSVLYPNESVSRNVTTYSESRSTDLPAHIVAYHEHIDKTQPETSMLMISNFQAQNHIWIAKLIGAKRILEIGVYVGYSGMVWSHAVGSEGTVTGLEFSADYAKQAEEAWAANGIKNASVIVGDALETLPTLNPSEPYDLIFIDAQKSGYPSYLSTILASSPKDGSKNRLLRPGGLIVADNVLRRGIVADDSDENPWVQREKGERAAYWKSEDVDKLREFNSAVHDEPRLDSWLMPLYDGVHLARLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJB9</accession>
    <name>A0AAD8XJB9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxidase</fullName>
            <ecNumber evidence="2">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_718604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366235.1">
        <property type="nucleotide sequence ID" value="XM_060512095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJB9"/>
    <dbReference type="GeneID" id="85395993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="3">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="40454" checksum="F91A728114E37FFA" modified="2024-05-29" version="1">MSVVVANAGCGGARMPFRAGRVDASTAGPAGVPEPQTPLNTTLATFAKAGFSQSEMISLVACGHTLGGVHSRNNPHITGLDPSPDTVTKFDSTFDDFDNRIATEYIRGNTSNPLVVGRNETLNSDKHIFSSDGNKTIRDLGCTKNGFRTACADVFTHMIDTVPATVQLTEPVEPVDIKPYVTLALGGNGSLAFSGWVRVRTTEGTGRDAGDLAVHLSFADRGGQGSVVIPATLDGGGVTYGLWGETFAWYQFETAISANDGAGFPLDDALLYQAASSCVNRTSVNNERTFTVTAAVLKERAADAVTMDIVRLVRRSEAIHRRLDVESVELAATGEEDSGYALLRAQVQLATSGWSTSFDLVLGGEKEVRVDFLKTQACPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJI0</accession>
    <name>A0AAD8XJI0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_615642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366670.1">
        <property type="nucleotide sequence ID" value="XM_060507907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJI0"/>
    <dbReference type="GeneID" id="85391806"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF14">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="35019" checksum="127394F4A6E4F782" modified="2024-05-29" version="1">MNEMQQPLTDSTGVSHEEDGISGSLEENDDIEKALLPSKDAKTGSRTVGKETSWLKLGSKKQSLVTFLNISLFTASFTLWLRSAPMRHPLNVQDYWKETSFYSPILEHFDIPRISRVTNGTLYDTNPPSVLRQRIGKEADKEWHRIGDHVWPLVIGEADVRQLGKDPRVAVKIPEALGYGSDAYIAQTEVFHHLHCLDMLRREVSYEHYYEPKEGPRPGGDQHQAHIGHCFDILAQAIKCTGSVDMITFNWVENWEQPFPDFRNHKVCRDFDALLGWVNENSMDPKVFQEMKAPPPGWPVMPEPGPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJZ2</accession>
    <name>A0AAD8XJZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Altered inheritance of mitochondria protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_126921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368470.1">
        <property type="nucleotide sequence ID" value="XM_060501190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJZ2"/>
    <dbReference type="GeneID" id="85385089"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021582">
        <property type="entry name" value="Aim21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11489">
        <property type="entry name" value="Aim21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="896"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="766"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="839"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="919" mass="98945" checksum="A25BC9FF216D45D1" modified="2024-05-29" version="1">MSTASVQQPVIPPRPSRSQDKEENTNTSSLPKIPPRPIKRFDRSVSPNPDRYAPSPLNESPFSKSPKATRSSPSNGFLSSHDPIHHRPGSVSMPSVGEEGNEYDAINDGFVKPPPKAPSSPEHTRFAAEDLKLHAPKPTVPAQSAKQRVMAVTRTDSDKAASYGIGKPSSDDTRPSSLRKKASSSALSQKSESAYGDEEHGIPEIGQRVPMNPNLGDVQAPSPAPGSGAPPESLRSGTPRNHSRKHSSRGFNELPPGSYGLHGHSSALPTDKFEKAWYDKHPDFLKKDCKPSLHDRQNDYAMSSTDLNKIVKETHSRGSGMGTSASYVGTPSEEVGYQASAEYTSRISSPELQRIKSPQSPSRDSHPQVSVSSPDNATGSDDGTVHVDESHNRRRSFVSHDPGHENKYNAPILAEDESGGDVHPYDLQPAVEPPPERSGSAFEMEKPNRPTSRPTSIYNNNQSQTDLVHTPLEDVEEYEPLFDEERPEAKKSEAEAASSKPRHKFPSKDVWEDAPDSVNYTAEVSTPEPTESERPSSRRRSELPTENPALEFARRQEELAEQEGRGVDAKQLKPVPAALQKAKEEARPAMANRFPSRDVWEDTPESAMHEAIVDTPEPKDESPVEKPFVPARPQKKGSQSSATAEPPSIPERPRKQNSTSEDKAKPAVSEKSKPQIPARPTKTLPSGVDSKEQDSAPKQKPAIPGKPAGGKIAALQAGFLSDLNKRLQLGPTAPKKEEPSAADVAEEKEKAPLSDARKGRARGPQRRAPAAKSPAPAAAEAKSGPTLSFSPLRICWSIGDSGVLEVDDGSKEEATKETIPEVASTVAETKEIKPDVSAETEAPEVPATTEPAAETAEVAEAEAPTPVGAKDEAEAPEEVVKTLAANTAGEPVVEATLEKGADIEPVDVKQTGGEARFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKB6</accession>
    <name>A0AAD8XKB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_88991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369012.1">
        <property type="nucleotide sequence ID" value="XM_060515977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKB6"/>
    <dbReference type="GeneID" id="85399875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042201522" evidence="1">
        <location>
            <begin position="19"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="111"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="392" mass="41903" checksum="104E72C117ACA15F" modified="2024-05-29" version="1">MKSSNIAVWLSIAAGALACDGGHDDISALDTGLAATDSNDAQQQLRDRMCASSPLTVASLQSIITKNDTSQYGVLDTADESHVDEGVVPDGLGDSEEARIRYGTNLKSPSGLWQVRPSPGKGLGIFAIAPIPRGTVIIDERPLFTINPGALTPGQGFAFAAIATLVDQAFAQLDASSRTAYLSCPAHRDPGGADAGISREALIFRTNGFTMSSGEIGIFPHIAKLNHACRPNAGSASVGGRRVIWAGRDIAPGEEVTITYAPLVQDTDSRRARLAQWGFTCDCAACEARDDDDKRIEMKRLMGIIERELGSDAFGGDVLPDAERLVKLVEEVGLVDYLGKAYKYASYAASRSGKFGAARKWARKELKIHEIADEESEYARETRAFLASLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKJ3</accession>
    <name>A0AAD8XKJ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_738306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369115.1">
        <property type="nucleotide sequence ID" value="XM_060513021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKJ3"/>
    <dbReference type="GeneID" id="85396919"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF3">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="694"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="722"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="821"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="695"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="761"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="877"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="891"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="938"/>
            <end position="955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="986" mass="109214" checksum="F5387C15CB27EE63" modified="2024-05-29" version="1">MSSTDLSAQQQQQQQQLNQQQSPQKSESPSQAPGTSTNPAGTSPNAQGSSAAAAAAAAAAANHLSFRRQRASRACETCHARKVRCDAASLGVPCTNCVAFQIECRIPTPKRKKTTNAGTNKDSDRSASASPFPHAPSHGLTEVCSSEKGDNAEERSPRAPSVPAPGPGTFPPRTPAVYHTTDGTPSSTYTESQARKEEVDSGTYLNLVMKPKFTRAPITDAGRVAYLGESSNLTLLVHDRQGSSDVVHYPLPENVRGSRARLTELDNVEIDILHQRGAFLLPPRSLCDELIDSYFKWIHPIVPVINRTRFMRQYRDPKNPPSLLLLQAVLLAGSRVCTNPQLMDANGSTTPAALTFYKRAKALYDANYEDDRVTIVQSLLLMGWYWEGPEDVTKNVFYWSRVATIVAQGSGMHRSVEQSQLSRSDKRLWKRIWWTLFTRDRSVAVALGRPVHINLDDSDVEMLTEDDFIEDDGDRNSEYPPDPIHVQFFMQYVKLCEIMGLVLSQQYSVASKGRQRNAIDLTHSDMALADWLQNCPKIVYWEVARHHFWSALLHSNYYTTLCLLHRAHMPPNGGSRFPDDSPYPSRNIAFQAAAMITSIIENLAAHGELRFCPAFVVYSLFSALIMHVYQMRSPVPSIQQVTQDRLRTCMQALKEVSRVWLVGKMVYTLFESIIGNKVLEERLQKAAGKRHRKAQQALAQLEQQQRPQDVAKRKYDDMAIDFSVNTPTPQESYERSRPQTPSHMKGDGGPNQQTMPPPITSPNVRQNADTFMGGTSSRPQTRPATPFNPSFSVPATPPDLYLVTRNSPNISQSLWENFQPDQLFPDSASMPAFPHMSPPPNHHGIDTGLMAQLQNQNTSHGLPAQNSQFQARGPTKQGLSGSPQQGTNVLGSGMQGFQQQQPQQQQQAHGQGQSSNNNNSLNSNLWTANFDGLMPDGQSPSDSWSTGSAQGQPVPNTLNVEDWFQFFGINNGDLASMNLDLGLGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKL2</accession>
    <name>A0AAD8XKL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_606536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369114.1">
        <property type="nucleotide sequence ID" value="XM_060507387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKL2"/>
    <dbReference type="GeneID" id="85391286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="104" mass="11592" checksum="4A3069861F5009F4" modified="2024-05-29" version="1">MSSLLTGLFRLPASISSAMARVPAHTAPTAPPPPPPPFWLLKIQNCHGDMLKWWTRELARRTALPPGWEALTLRPESSLVSCVSSRTAHERFPRAEPEQEMAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKR1</accession>
    <name>A0AAD8XKR1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_70582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369217.1">
        <property type="nucleotide sequence ID" value="XM_060511516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKR1"/>
    <dbReference type="GeneID" id="85395414"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF18">
        <property type="entry name" value="ESTER HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="36007" checksum="1D464421E2BC16DF" modified="2024-05-29" version="1">MTLLTALGLRRKNDWEPLTLIDALILSPLNLLVTIIYSIILFLRGRPFTPPRDKPAIRIVCLSDTHDRTDVDIPPGDLLIHAGDLTNAGTVADIQAQLDWLAAQPHQHKILVCGNHDSFFDPSARLPEDRGKSLDFKGIRYLIRDAVTLEFKGGRHLKIYGAPDIPTCGGSEMAFQYDRSSPPWTNTVPIDTDILITHTPPKTHLDLNLGCPALLQEVWRVRPKLHVFGHVHWGHGRQTVHFDDCQRAYEALMSRPPRGLFRDLFPHAGWRDALAVLGYGIHGVVWKWLMVGPGGNTSSLMVNAAQMYGNTGRLGNPVEVVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKT4</accession>
    <name>A0AAD8XKT4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DnaJ homolog 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_70859</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369224.1">
        <property type="nucleotide sequence ID" value="XM_060511562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKT4"/>
    <dbReference type="GeneID" id="85395460"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="10">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="229"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="474" mass="49260" checksum="7D5850E384F2E9F2" modified="2024-05-29" version="1">MNASILTKAAAPGRLLSSRISRQSKLKDSVCKRAQIHTVTCTVRPTKPLASRVTSQAPSSKRAFHATSANLAPSDPYKTLGVDKSASAGDIKKAYYGLAKKYHPDTNKDAGAKEKFGEIQSAYEILSDPKKKQQFDQYGAAGFDPSGGGGDPFGGAGNPFGGGFGGQGGFGGAGGFNFDDIFSAFTGGQGFGRRGGGGGGGRNPFQQEILVGDNIEVQSSISFMEAAKGTSKTITVTPLTECGTCTGSGLKQGTKRSACKSCNGTGTRVHFMNGGFQMASTCGSCGGTGTTIPRGSECRSCAGNGVVRERKTITVDIPAGIEDGMRLRVDGAGDAPVTGKNAEAGMRTQKGDLYVFVRVATDPKFRRAGSDILYTASIPITTAMLGGEVTVPTLDGQVNVKVATGTNTGDKLTLSGMGMKKLNGRRGGSGDLKVEFRVNMPKYLSANQRTLVEMLANEMGDKTARKIMNVTPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB7</accession>
    <name>A0AAD8XLB7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Origin recognition complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_748264</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369563.1">
        <property type="nucleotide sequence ID" value="XM_060513588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB7"/>
    <dbReference type="GeneID" id="85397486"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001597">
        <property type="entry name" value="Origin recognition complex subunit Orc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032705">
        <property type="entry name" value="ORC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14629">
        <property type="entry name" value="ORC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="355"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="284"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="322"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="872" mass="95101" checksum="53952B3BE98E6990" modified="2024-05-29" version="1">MGANDSTESRKRSRATPAKPDHSVPSSFKKRKLDANGNPIVASSPTTPKTTPGANSSAVKKFARSKITSSPVSAYDVPDSPEDNPPRRIRNVRSVDRPTAKVPIPPRRNVDVDIYDIPCSDDELHSSPKEVNSQKASPTKRKSNGAVDHDVNEVHGGETIEKPQLRKGKSNKALGQDEKVASTEESSSQIRSSGRRRTLTAKALEHVEKVASRSATPTSLARASAAANEVPESKKATGKANRNISMPLKGILTPSKRDGTPRRSKSVAFDSASALAQEEVFFEDLPTKSGRSQKPSQKVVEAKVAVAKPAKSRKAPPKVIDEEPQEEEEVESGVEDQQDEEPVAEASEQEEDEDEDVCSICTKPDSKPGDRILFCDGCDKAFHQKCYNVSKVPRGDWFCNDCVGQKQLRAVAADEAVKTPNFAQHLSNLQRVLLDRCTGRRRIKLIDQDDAYEKAHQLVEQTVLAGEGNSMLVIGARGCGKTTLLESIVDDLSLQHKKEFHVVRLNGFIHTDDKLALKEIWRQLGKEMEAEDEANARSNYADTMASLLALLSHPSEMAQAEEGVTSQAVVFIIDEFDMFAAHPRQTLLYNLFDIAQARKAPIAVLGCTTRMDVVESLEKRVKSRFSHRYVYLSLPKSLPAYWKVCKQGLCVDDEDMDVEGIDVSVDGHEAFHANWKAMIEVLYKEKAFQSLLQYHYATTKSVSAFLSACILPLSALSSTSLDLVIPPTPSGAVVSLTPPNSKLHLLSSLSELDLGLLIAAARLDIVAHTDTVNFAMAYDEYGSLMGRQRVQSASSGLLALGGGVRVWGRGVAGLSWERLVALGLLVPAGLGTGRASGYGGLEGKMWKVDVALEEIPAGLKLNNVLARWCKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM49</accession>
    <name>A0AAD8XM49_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_647519</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370017.1">
        <property type="nucleotide sequence ID" value="XM_060510089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM49"/>
    <dbReference type="GeneID" id="85393988"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23134">
        <property type="entry name" value="RING-HC_ITT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000112">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000416">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="14">
        <location>
            <begin position="11"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="182"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="186"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="507"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="507"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1729962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="664" mass="72646" checksum="FE968C0B6EB85072" modified="2024-05-29" version="1">MDDDSDDPRQDELSSLQAIFPEIELDDNQPFRFTIELPVHPAKPVTVTFPAASNVDDTAAAQLPGVEPRVDSHELSHLPAVVVRMDLPMGYPSDNPPSVSISTSPPWLSEDVTKKLEDDGPRLWEDMGRDMIVFTYIDQIQQAADDVFGMVDGAGALEVDPLHKIAILDYDIEATRAAFEKETFDCGVCLDPKKGSMCHKMLDCGHIFCTQCLQEFYSNAITEGDLATVRCLAPNCSKERAEAARGPGKSKKRKVKTSISPSELLQMGLPHDMVTRYVTLKYKNELESDKNTIYCPRSWCQGAARSKKHRKPEGLETIDESSDEETEEETDADGEDGAGEKKKKAKKNFEAGDLIAICEDCGFAFCSRCYQSWHGEFIRCTPKRDKGEISEEEQASIDYINLHTTPCPTCGVPAQKTHGCNHMICFRCASHFCYLCSAWLDPRNPYAHFNEQPNGKITSCYMRLWELEDGDGDNVDIGFAGGHQIEQLLEIPPPAPPAPVIDLVPEIEEPDDSDSDTEANDADRPARPAAGGVAREGPLVLRIEANPAPRGGRGGAGIGAALHGPIPPAAPQAPPVHARRGFPAARGGRGGRGGRGGRGNHRGGPRQNQQPEARRGAPPRRHEDFDPNMVEGLGDGELDAAQQAWIRNFVQMALADQEGDSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMF8</accession>
    <name>A0AAD8XMF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_715868</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370096.1">
        <property type="nucleotide sequence ID" value="XM_060511793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMF8"/>
    <dbReference type="GeneID" id="85395691"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003214">
        <property type="entry name" value="PRK04179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="94" mass="10653" checksum="B6914B3E7766F3B3" modified="2024-05-29" version="1">MTKGTSSFGKRHNKTHTLCRRCGRRSLHIQKHTCSSCGYPSAKTRKYNWSEKAKRRKTVGTGRMRYMKDVSRRFKNGFQSGVPKGSAGPTAQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMH8</accession>
    <name>A0AAD8XMH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370165.1">
        <property type="nucleotide sequence ID" value="XM_060513496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMH8"/>
    <dbReference type="GeneID" id="85397394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF564">
        <property type="entry name" value="STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="347" mass="36957" checksum="7049A17F587D701E" modified="2024-05-29" version="1">MTDDLILLSGATGFVGYKTLITALEAGFRVRCAVRSKAGIDKILAAPSIKNINPTKDQLSWVIVPDITHPGAYDEGVQGVTYIVHCASPVPTFGKDERVGTEEEVYVKPAVAGVLGLLESAKRHAADTLRRVVVTSSIVAVVPMECFMGQGLDRPAIDGKSRVATPAAPYGSGFGAYRASKIAALRASEAWMKEHGTSTNFDLVSIIPAWIWGRDELSTTAESLLSGSNSVLLEYLRGRKSDTPILSSFVSVDDVAASHVRALSPSVSGKQSFLLGRYVAMEEARVIAMENYPQAFADGVYSADGSQPTVSIPTDASEGERLLGRKFVSGGDMVRDVAGQFLQLDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMI9</accession>
    <name>A0AAD8XMI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_567017</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370141.1">
        <property type="nucleotide sequence ID" value="XM_060503912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMI9"/>
    <dbReference type="GeneID" id="85387811"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="9">
        <location>
            <begin position="83"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="300" mass="33488" checksum="1F86EBAD30D913CC" modified="2024-05-29" version="1" fragment="single">IVFIHGLKGHREKTWTSDKASEPWPKALLPSEIPNARILAYGYDADVAKATEMVSVSRIRDHAATFLKRLTNFRDRTDSVGRSRFFNVLSLRVRIIFVCHSLGGLVCQAVRALARAYTREHLKEVLEATRGILFLGTPHHGSALAVWAERLGKSVGVLKQTNTEILGVLRPESEVLAEIQDNFHNMTQSQTQEGVGTIQITCFYEELPLPGIGLVVPQHSAIFPGKDAIGIHGTHHTMVKFSSLEDSGFIDVCDELRTWIKRFDRKVSVPQRQSMPPPAVEDQNEKRSTTPQKKTASKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMR2</accession>
    <name>A0AAD8XMR2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_426983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370244.1">
        <property type="nucleotide sequence ID" value="XM_060503015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMR2"/>
    <dbReference type="GeneID" id="85386914"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000145">
        <property type="entry name" value="Pigment biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF12">
        <property type="entry name" value="CONIDIAL PIGMENT BIOSYNTHESIS PROTEIN AYG1 (AFU_ORTHOLOGUE AFUA_2G17550)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="46977" checksum="BDFD1258BDCD6310" modified="2024-05-29" version="1">MSPHKLPEQEDGKRQWVMGTEAFERTMPHHQGIKALWETKWKFPCTKSVYPFHDGQYEDFEPIFEHLIKNNINDGNSTAYTEAFFPIAESLTSKGDEAIMAGNKKEASDLYLRACTVYRIARFPYITAYPEISCQVKWKAWEAQKRAYMKAAQSWDCPIDEIDIPHAHAKGADWKSIPAYVRVPPGASQSKPSPVVILMTGLDGYRPDNTVRSDEFLARGWGSVIVEIPGTADCPADSADPESPDRLWSSVLDWIAADGRFDTSRVMVWGLSSGGYYAIRIAHTHRERLIGSIAQGAGCHYFFDPEWLEKADGHEYPFLLTPAMAMKHGYKSVEEYKAGVQKKFSLLETGIIEKPSTRLLLINGTLDGLMPIEDSMMLFEYGTPKEARFFSGALHMGYPMANGSVYPWMESVMSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMR6</accession>
    <name>A0AAD8XMR6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_747496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370328.1">
        <property type="nucleotide sequence ID" value="XM_060513446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMR6"/>
    <dbReference type="GeneID" id="85397344"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042252312" description="Secreted protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="12592" checksum="B73F90E4163CA405" modified="2024-05-29" version="1">MHIRLHHFVLLLAALLCIVDHADANRSYYTWFRRRCCNQPERKMCREALVRWRICNDAARRGGLPPPPCIWTQQWWERAHQACRPGIEGPSDWVDPDKPVLPKTEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN18</accession>
    <name>A0AAD8XN18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_566660</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370381.1">
        <property type="nucleotide sequence ID" value="XM_060503872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN18"/>
    <dbReference type="GeneID" id="85387771"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="86"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="133"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="57855" checksum="2ED8EB84350519D7" modified="2024-05-29" version="1">MAHSSPSRRSQHNSNIKSSPERGFTADFLSENRNSELSHRDALAAAQLEHERVRLAALRVYEVHQLQEEKQRLEAEQRRIAQLQKEEEDRLKAEAAVRAEQERLRELKAKQIPQLPPEPEPAPPKPEPKKSQEPQINGTTAANAEPAAAPLAAPKPAPLTTAPTSALSAVKAPPAAPSSAPAQVAATPSTQSNGFLSKPAAPPAPKPAVQPAAAAPTPAQPIVDRYTQIHQALKKLRKDVEALSKQPGNPLKGKLGDMRRQIRKSIGQLTAGKGANAQPLATINAALRESLGGQVPSPLIDASIYVQQSREPADGAVNNGPQLPALFIYLLNILSKAIIQQFSNEGGANPKSAEPVGIVTAQIFSNKDYHWRGGSMIDILIAKFRVACPVLFGSRGSDKTEGGRRAIGWKKENGNWVPEQAHNDRMTGLGAGFAAIALRDFSKASKTNPYPPTNYWKAMAQIVNSPPQLVSNTQYVVLKSMIDGHEQRFINFYGNAAVAALRMALVEFPKRAPPGATAAQALQVLGDVLRRDSGLDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNS1</accession>
    <name>A0AAD8XNS1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_333684</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-K/MCM22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370796.1">
        <property type="nucleotide sequence ID" value="XM_060502428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNS1"/>
    <dbReference type="GeneID" id="85386327"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020993">
        <property type="entry name" value="Centromere_CenpK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14401:SF6">
        <property type="entry name" value="CENTROMERE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="36503" checksum="A1CBCE4CA943CDA8" modified="2024-05-29" version="1">MDESPRPVSDRYTLSLDQSLQELQEKIEQHREELAALQRNANSSQNVSGPGRGSYEVMKGAFEQVASTPPFVPFSESVLPALLALRTTHQTVVESQVYLTSQGATFDQTKRRLEVEQANLSDQKTLQQSLEKRVLSLKDEAESRMELTPEQAAKKRLDELRQKKKRYDKETTKLLKALRNFIDGHLGGQLAAEDLGGPVVGDMMEIDSDQLGAGFNAQGRPVKVKFNVDEDKRQRRLEEVWGLPQEDAGRGKGNADEAAAAGREMRDLTEQLLNQHAEAAGDSTAAYVKLSKETAAARFLVRSKVAQFHPRDATRLKLIDFGRELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPW0</accession>
    <name>A0AAD8XPW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_246646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAPP small subunits family. BET5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371399.1">
        <property type="nucleotide sequence ID" value="XM_060501906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPW0"/>
    <dbReference type="GeneID" id="85385805"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14855">
        <property type="entry name" value="TRAPPC1_MUM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.70:FF:000013">
        <property type="entry name" value="TRAPP complex subunit, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF16">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4 6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="18769" checksum="A1CDA963C953F39D" modified="2024-05-29" version="1">MVVYSFYIFDRHTECIYSKTWLPAERPPSQQPPSSAGTGAAPPSSQQLGRRSQVNSAKDDAKLIFGTVFSLRNMVRKLGGDDDAFISYRTSAYKLHYYETPSNLRFVMLTDTATLSMRNVLHQIYINLWVEYVVKNPLAPAEHKGGEGVKNELFELGLDQFVRGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR47</accession>
    <name>A0AAD8XR47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="15">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_8892</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371949.1">
        <property type="nucleotide sequence ID" value="XM_060515976.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399874"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.140:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000684">
        <property type="entry name" value="RNA_pol_II_repeat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00115">
        <property type="entry name" value="RNA_POL_II_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="18">
        <location>
            <begin position="242"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1556"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="689"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1561"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1610"/>
            <end position="1708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1709"/>
            <end position="1723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1731894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1732" mass="191625" checksum="0D7C61598126181E" modified="2024-05-29" version="1">MANLYFTHSSAPIKTVEEIQFGLMAPEEIKNMSVCHCVYPETMDETRTKPRDGGLNDPLLGSIDRQFKCKTCNQAMGECPGHFGHIELAKPVYHPGFIKKVKKVLEIVCHNCSKVLADRSDPEFLQAVNTRDPKVRFNRIWNICKKKTRCENEVKEQKPDDGEYGLNMKQAPVNHGGCGNIQPRVRHKALQLIAKYEAQGEDGVKKKEEPPITPEMAHNILRRISDDDLRDMGLNLEYARPEWMIVTVLPVPPPPVRPSISMDGTGQGLRNEDDLTYKLGDIIRANSNVKQAIREGSPAHIAQDFEQLLQYHVATYMDNDIAGQPRALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVITGDANLSLDEVGVPRSIARTLTYPETVTPYNIGRLHELVQNGPNEHPGAKYVIRSDGTRIDLRHHRRAGQISLEYGWKVERHLITGDYIIFNRQPSLHKESMMGHRVRVMPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAEVKELCLVPINIVSPQRNGPLMGIVQDTLAGAYKLCRRDVFLTKEQVMNIMLWVPNWDGNIPQPAIIRPRPRWTGKQIMSMAVPNIVSLHSAPDSKEENPLKDEGLLIQSGQIMYGLLSKKNIGAASGGIVHIVYNEHGPQAAMKFLVGVQQTVNYWLLHNGFSIGIGDTIPDKITIEKVQIHIDEHKAEVEEFTRQATANELEPLPGMNIRETFESKVSKALNTARDKAGTTTQKSLKDLNNAVTMASSGSKGSSINISQMTALVGQQIVEGKRIPFGFKYRTLPHFTKDDYSPEARGFVENSYLRGLTPSEFFFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDVSAKYDGTVRNSLGDILQFLYGEDGLDAIYIEKQRMDHLNMSHKKFADRFRLDVMDENRPEELEWLEYGNEMAGDPAVQQLLDEEFDALLSDRKQVREINFKRKDDESMQLPLNLIRLMETAKKLFAVEDFQRSDLRPQDVIPKVQEMLNRMTIVRGNDDISKEADYSATILFKAQIRSRLAFKRIACQQRLNKMAFEHVLGELEARWDRAFVSPGEMVGVIAAQSIGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEILNLAQNIKTPSMVVYLSGEDNASQEAAKQLRSTVEHTTLRSVTAVTEIYYDPEITSTNIPDDLDMVESYYLIPDESHDKTEDQSRWLLRLTLDRQKLLDKELTVEDVARRIKEEYPNDLAVIFSDNNAEEQIIRIRPMHAGNDKDEDGEKKIEDDVMLKRLETHLLDTLSLRGVKGIERAFLNKEVKLIETEDGALLAAKADERCSEWYLDTSGTALRQVLAVDGVDSNRTYTNHLWQVVEVFGIEGARAALIRELTQVLAFDGSYVNHRHLALLCDVMTYRGTISAVTRHGINRADTGALMRCSFEETVEILLEAAAVGELDDCRGISENVMLGQMAPMGTGHFDVLLDPKMLETVISDNSRMGLMPGMPVKGGEAGGAATPYDSGSPMADSGYMSLSSPAAGNFSPIVGAGSDSPTGFGTEYGGGGFGSIGSVNPYSSASPGRPTSPFSTSPTSPFSSGYGGYSPSSPNAGYSPTSPLIDGAAGRYGATSPQFSPSSPSFSPTSPMLRPTSPASPNYSPTSPSYSPASPSSPRHYSPTSPAQYASPTSPSYSPASPNYSPASPNLHGAGPTSPSYSPASPTWSPTSPAQYSPTSPSFQQTPRTPGPGGSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZC9</accession>
    <name>A0AAD9CZC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_568600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369332.1">
        <property type="nucleotide sequence ID" value="XM_060504091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZC9"/>
    <dbReference type="GeneID" id="85387990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="651" mass="71792" checksum="168F623880318B5D" modified="2024-05-29" version="1">MNPQHSGAATLPKGFRFHDPDQQNPKTPEPSAMDEELQPPSPPRPRLRLKRRVASNLNAPTTHFLASVAAADVPIPSIEEPESAGPDTQTQFSSMTYPVIHNLNDLDELALHKLRGRRFSPPKTPAPGAAPSLSPRRYPNWSIDSAFSSGESTPECESSRPSTARSTQTSASLFSRFSLASEDLQCISPETDASDHVKRSFFDAPEEPTEPSSSLKPKAKRRKAPWTKAMSDHLWVTYLTYLQDPKVTPFRTAKSGVPPHGVCLRVAREAKRSWRGPKGGRKSLNPKSGSSTPTVETCTFLQWPHTCASTRAHLRDLCKLKAASSSARTSKFLANSPTPFGRTAARFWNRRSTPARSPSVFSAHDMSMSLTLSTSEAMQPQGPLAQLTKSEREPAQESMTEPFPLFPMEFPKVDAPLEDRPRLGTPFMANSYGPSSTGALAAAVSSVPQRQNQSLGHRRTLQSPARLTRSRSNTQKRVGRPRQASHEPRKTKRPSLVSDLWTEPMPSESLPKTPVKPEVEFSSTDRNSHDDLFVPRTSLSGLFTAPMQIPAPRLQPANLPDPFLAAPNAPPARLGSPFPGTKTSFSFPNRFTQPDELDHGTIRPFATIQQQASGDGSSAPRNLADRLAYIDERLRNFRRRGSNRRRSESPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZT1</accession>
    <name>A0AAD9CZT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NOT2/NOT3/NOT5 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_605419</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369573.1">
        <property type="nucleotide sequence ID" value="XM_060507336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZT1"/>
    <dbReference type="GeneID" id="85391235"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="327"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="456" mass="48869" checksum="C91A73103239B641" modified="2024-05-29" version="1">MLTWNFLEYTGSNGSGWAFGGGVPMGGAGLPNQARQLGGNVSFAQSLSGSQPATPLDLSEFPSLSNNAQMNTTGQSNMWSSTASRNLGAGPVPRNQQSTPLSAQSGQDELFTPTSARQGAFRFGGQSSAGPAPQAQSNPVDDFPPLNRNSNGEIGGERSANLMPSLGFGGSQASGSTAAIPPARSAGAGNGLLNALSANSRTSDGRSPSIASVQDQARIQEASAERGNSFSEETGGDSASQSVETRNPPGAIGNDAVTGNGKAKEEKEGQSPDVQDPLAGMAPIDKFGMKGLRVLMNNYPSYGALMQGMDPNEFGLNVNSPDLISTQIYSLFDDTPPRPAIPSVRLPECYKVTNVQPIETKIPSFNEETLFWIFYSCTQDVKQQLAAVELHSRNWRWHKKLHFWLTKDELMMPASLGPHHERGYYIVWDTTNWRKERRELTLHYGDLETNLAQPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0N8</accession>
    <name>A0AAD9D0N8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_30940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369456.1">
        <property type="nucleotide sequence ID" value="XM_060502301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0N8"/>
    <dbReference type="GeneID" id="85386200"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9336" checksum="8FC3B0F182B05C95" modified="2024-05-29" version="1">MLQSYLTAVSNIGHVGGSPVARHPSTVPLNRIAKDSCCRLTRSNQTPKERQREDVDLDMHQQRAVESSRFERSRCSPPGRGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1I7</accession>
    <name>A0AAD9D1I7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GrpE protein homolog, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_566437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370668.1">
        <property type="nucleotide sequence ID" value="XM_060503850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1I7"/>
    <dbReference type="GeneID" id="85387749"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="26721" checksum="ED21F5FE1DD9C872" modified="2024-05-29" version="1">MFRQAIATSSRAVRTGIRTQTPKSVFQNQFQSSPAFRIRAAQPAVARWYSDAKETTEATKEGEKPADDAESALKKQLETKEKEAADWKDKCLRTIADFRNLQDRTQREVKQARDFALQKFSKDLIDSIDNLDRALSMVPQEKLKVEEKSGDLKDLANLYEGLKMTDDILMSTLKKHGIERFDPEGEKFNPNEHDATFMAPQPDKEDNTVFHVQQKGFKLNGRVMRAAKVGVVKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1L5</accession>
    <name>A0AAD9D1L5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_647291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370174.1">
        <property type="nucleotide sequence ID" value="XM_060510060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1L5"/>
    <dbReference type="GeneID" id="85393959"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="140" mass="15245" checksum="07F3D094739164D3" modified="2024-05-29" version="1">MTCWPTALITLLRWSADENSFLARIISVAPAPLVLESSAPGVAGDWGQVTKERLQRLAGWTMSTRSGVAGSLPAVSVVEVGMKAVDRLVRKRPDRLSEGKCSERRIDWPVSSVVLDWNLTENKLSPVKGLTPPPIVSEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D274</accession>
    <name>A0AAD9D274_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_747278</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370550.1">
        <property type="nucleotide sequence ID" value="XM_060513408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D274"/>
    <dbReference type="GeneID" id="85397306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF147">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="423" mass="48022" checksum="06171A651000CDF8" modified="2024-05-29" version="1">MDFYSRATNDGPVHAFVNPFVELNAGLWSLFAGATVFLALRLWCKITRRHGLWYDDYILVISWTLLLANNILIVYEFATGYVLKDSSEQWDDRMHILINISSCGTLIGQAWTKSAFGVTLIRMSNQWQRWILYFCIVTMNVYMIAKVVVQWGKVCGSKSYEGDYRLNFCLEKKFRDDFKEGGNVYNIIMDFVFACFPWLITRSLEMRRAEKVGLCITMSLGMIVAIVAAIRVSWKDEGNGRDQWYIWRNGLSQVWYSSEITGTIIVQCIPILRPILREIHTSLTSKRLESTAGGQSTTFGSKLSSGKRISTGVMQNDKQGNERIALREIPEEPADDSPYWKQDPARSSDSTTSPSETDFKPRPPTAPLPDMWPLSGNESADLNGSHSGKSLDFEHDPHNISHLDVEQGHVQQGLSPPPPRRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3C0</accession>
    <name>A0AAD9D3C0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_246442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371391.1">
        <property type="nucleotide sequence ID" value="XM_060501902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3C0"/>
    <dbReference type="GeneID" id="85385801"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="28482" checksum="AAC2F9734EFFF932" modified="2024-05-29" version="1">MAKVQASCHLAESEHELQRGERNQSAREDTIAAVWQIMLVIKKFGGEVKLLDRLRQAQERCHRPMRPVSDEVETMLRNDLKVLKNARVRPLERLEKSPSQDEFPRNETLGGPTRSSERPGRTPFLQFARFSPRMRRIVKPNRAGQIWGARGAHPRNNRALKRAGGQLVKDSRLRLVSDRRQDRGGPYVIVHPYGFIYKCVKKGRYTSESHCRTTCAPLAKRQSHSHHHHHHHQTAKSIKGLEPNKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5L4</accession>
    <name>A0AAD8U5L4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_643846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000232">
        <property type="protein sequence ID" value="KAK1706099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357747.1">
        <property type="nucleotide sequence ID" value="XM_060509699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5L4"/>
    <dbReference type="GeneID" id="85393598"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000001">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="302"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="454"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1706099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="624" mass="69311" checksum="F012CF0E1D8A603A" modified="2024-05-29" version="1">MAAINYLLYEAPMGYGVFQIEHQPDSIGLRQKEAQETIADLSKFGKMVKLVNFTPFDTGKQALDEINHISEGLMSDHLKSVLELNLPQTSGKKSKITIAVAEKNLASVIKSTFSGIDCETSETSEVAGDLLRGVRLHADRLLKGLQTGDSTAAGLGLGHSYSRAKVKFSTTKNDNHVIQASATVEFQDKGVNQFFMRVREWYGWHFPELVKIESDNLTYAKLVLAIGDKATLTDDRLHDIAALVEEDGEKAQAIIDAAKVSMGLSITPADLEIVKGFAEAVVAQAEARRSTANYLDKKMSIVAPNLQTLIGTPVAAKLISHAGSLTNLSKYPASTLQILGAEKALFRALKTKSNTPKYGLIYHSSFIGKAAVKNKGRISRYLANKCSIASRIDNYTENPNTKFGEALRQQVEDRLEFYATGKKPAKNSDVMVSHSHPHSFPICISLDQYANISKRPPSWSKSRATSRSTTRKWSMPSPRTSRRRRRRRRKSPRTRRKRRRRSVSASPRSAPPSPKRQTAKRRRRRSPSPRMSKEDNVVSVQPPLLCTYPHLPQPCSKNSSGSFFNVGLAASTLGIIPGSSLSSCYLQPCGFFPVLFFFSWEFYGGEMREKPGLFERSFWALKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U699</accession>
    <name>A0AAD8U699_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_642288</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358246.1">
        <property type="nucleotide sequence ID" value="XM_060509602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U699"/>
    <dbReference type="GeneID" id="85393501"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1708214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="690" mass="76342" checksum="F3DA185575D3A563" modified="2024-05-29" version="1">MTSETQYSVSPPLATPGTVAVNPRKRGRTACTRCKSRKQKCDDQYPICSNCRKSGAQCDKADVADEASSIAYTRALEERVAFLENKLAQIPTPEATETPRETASNYSVPSGRDKNALSDVVAHVSLGNFEAPAYVGPSSGLSLALNLGEMVQATVWNKMLPDIQDGTAGNQANCINPSPRCITVEDLLAHSVKEPPSDEQGSQMLKAYTSQLHSKYPFLEPEELWKLHSERLTLAAKPTQTLTRIERFGIFKLYLVYAMGATLVQLTQRGPVFSPEALYITALQHISAARESRTVQNIEAMTLLVMFHLRSTSSHGLWYMIGLAMRTSIDLGLHRAAHEQNLDGPIVQRRRRLFWSVYSLERTIAVSLGRPLSIADNQIDVELPNTIINGSPSASVIVGNDITLALVLFKLRRIESKIHHSVYRTDKTLDALRPKLDRLHQELKFWRDSLADWIPAGHSDLNYALLLYNRALRLLIQPFLPILPATDPFYGLCMRAAGDICQAHKRLHQTLDYGHSFIAVQTVFVAGVTLVYGLWTQGNALWSVALSNDIRACSLVLFVMSERAPWVRKYRDAFEVLVNAAMEKLQDNEAGLAEMASAQMRAGKASGATECCGMQNPDLSGNETTTRPIDSSSNQFLMSEDGGIAVGEFEGAWPMVAELANWIDQDTEGGSPVWMPNFELLQSLSGTWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6D5</accession>
    <name>A0AAD8U6D5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_253671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000302">
        <property type="protein sequence ID" value="KAK1702693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357183.1">
        <property type="nucleotide sequence ID" value="XM_060501947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6D5"/>
    <dbReference type="GeneID" id="85385846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03057">
        <property type="entry name" value="GST_N_Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="101"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1702693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="226" mass="25559" checksum="38D55E1670E0CE23" modified="2024-05-29" version="1">MSSPTITLYYRPGSCSLVAHALLYHLGIPFKTVKLRPNADKRFEAADGSFTHEDYCKINPSGYVPALVLDSGEVITELPAVLTYIACIAPSEQTEKFLGSSAFDRAKVNEWTNWLSGTFLGASLAACARPYRFTDGEEARKAVAEKGWEHILECFDRIESRLEGREWAVGDDLTVVDMYMYYFRRSAVYMTDLGEYPNFERLQKKVEKLAGVQKVLEVEELKPVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U718</accession>
    <name>A0AAD8U718_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hydantoinase B/oxoprolinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_641033</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000177">
        <property type="protein sequence ID" value="KAK1709985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358681.1">
        <property type="nucleotide sequence ID" value="XM_060509529.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85393428"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049517">
        <property type="entry name" value="ACX-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19278">
        <property type="entry name" value="Hydant_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="3">
        <location>
            <begin position="256"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Acetophenone carboxylase-like C-terminal" evidence="6">
        <location>
            <begin position="694"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="4">
        <location>
            <begin position="783"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1709985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1349" mass="144401" checksum="25C1B8E22CEFD167" modified="2024-05-29" version="1">MAADIRVSIDRGGTFCDVIAEIDGREPLIFKLLSEDPANYPDAPTEAIRRVLKFVEGKPIPIGEKLDGSRIASCRIGTTVATNALLEHKGERFAFLTTKGFKDVCVIGDQSRPKLFDLNIRKPTALHSTVVEIDERIVPADYDLNPTPLDKEAALKAASTSPLTSSSSTPQEGDLVRTPTGDLIRILRRPNPDLIRSQLRAIKDAGYTSLAISFMHAYLYPAHEDLVASLARSPEFAFSYVTTSSSTSPTIKFLNRSTSTCSEAYLYPVIQRYVASFHAGFLPDAPPRRVDFMCSDGGLKAASRFRGNEALLSGPAGGVVGIARSCYDPQDGTPVIGLDMGGTSTDVSRYDGKYDYLTETSIAGRTITTPMLNIATVAAGGGSILFARSGLLAVGPESAGAHPGPACYRKNGPLTVTDANLFLGRLVPSSFPSIFGPSASEPLDTAVVEEKFKQITEEFNEQTNQTLQPHDVALGFLDVANETMARPIRNATEARGFAPETHNLVSFGGAGGQHACEIADKLGIRRIFIHKFSSLLSAYGIAQAELQSETLEPYGAKFKNSDGAVQGTVASHVADRLAALKEKVTQELVSQGADEASLVFDESLVLRYFGTDTNLTISRPDDGDYAASFKATHLREFAFSMDRDIVIESIKVRGTGSAAGSAFGMRETSATQELADRRSGASSGVAAAPEPSVKQRVYIDGEWRETGVYRLDEVPRGVVIEGPALLIDQTQTIFVSPTFNAYILSSHVLLEKQASAIASSTSLLSTSTAPTQIPQTEATETTDPILLSVFAHRFMAIAEQMGTTLQRTAISTSIKERLDFSCAIFSPEGKLVANAPHIPIHLGSMQFAIQEQHRHWKGRLQPGDVLLTNHPQWGGTHLPDLTVVTPVFVDTGSPSAGSDATDKTDGDEPTTQEIAFYVASRGHHTDIGGKGITSMMPESRQLWEEGLNVPTLKIVSRGHFLESDVVAAFEKAGSFPGCSTSRRLADNISDLKAQTSANQRGILLLRKLCAEQGEGRQGVAVVHKYMSAIQANAETAVRTYFKSLAVSHPSGLSATDHLDDGTPLHVNITIAPETGTATYDFSLSGPQIWGNYNCPISITHSAIIYTIRSLVGLDIPLNQGCLNPVDIILPPQGSVLNPGPGVAICGSTLASQRVIDVILRAFGTHGASQGCANSFGWGMGGRDPETGQVVKGWNYGESIGGGVGAGAGYDGEHSTHVHSTNTRQTDAEVIEKRTAVLVKSYGIRRGSGGVGKYRGGDGITREIQARIPLKFSILSDRRVYRPWGMAGGGPGQKGENYAFLFNEEGGMEKINLGGKAIINLKEGEYIQVNTPGGGGYGGKEVEDRHRGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U901</accession>
    <name>A0AAD8U901_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uracil permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_594990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000267">
        <property type="protein sequence ID" value="KAK1704299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357406.1">
        <property type="nucleotide sequence ID" value="XM_060506753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U901"/>
    <dbReference type="GeneID" id="85390652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF4">
        <property type="entry name" value="ALLANTOIN PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1704299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="63964" checksum="65CD7FC08148A756" modified="2024-05-29" version="1">MVNKTACRIKEALALKSDAFRHEEVSAWSNRDLIPLPPSRRTWGWFNFFGSWSLSSLNVATWQTPNTFLTQGLSVGQAMAVIVVSRALCCFFAILVAWCGLTWHIGFTVQNRYTWGFRASFIPLLQRILLNFIWTALQCWNGGKLVTVCITAIWPSFAKIPNTLSANTPTTTYELLGFTVFWVVSLPFLFIRPERFKKPFFVSSVACGAAMVAILAWSVAVARGVGPVFYQGEKVPSSSRWSASWLMMAGINQAIGGKAAGMTNSSDFSRYAKNKRDYIVGTVSVYWVTGVLVCLGGLVTTAACQKIYGQIYWNPPDLLMVMMDHGQGSPGSRAAVFFLALAFAFTSMFENVCSNAVAGGIDLAGLFPRYLDIRRGALLTFAAAWVIQPWQLINQAATFVAVLNSFAVFLAPIMGVMVCDYFVLRRRRVRLTHLFNPKGSDYWYRHGVNWRVIPCWVAGWAPTVGGLIVSAGGVGGAPDAVYELYYVAFFIGFMISFVLFWGVNVLFPVEDLGEYDKVDVYGTFTANEAVKLGVIPCEEEAVVSEFGKEEGIVTLAGEISEDARGEERRWWSLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U944</accession>
    <name>A0AAD8U944_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_594754</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000254">
        <property type="protein sequence ID" value="KAK1704900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357510.1">
        <property type="nucleotide sequence ID" value="XM_060506733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U944"/>
    <dbReference type="GeneID" id="85390632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054710">
        <property type="entry name" value="Tri101-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22664">
        <property type="entry name" value="TRI-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="553"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1704900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1178" mass="130090" checksum="EEAF005B09B47FCC" modified="2024-05-29" version="1">MTVPEQYGRRLIPQILDSLASVEPHRILYSVANSSNISYGFQDISARAFAKAVDKTAWWLHSQVGESSDVRTVAYIGPHDLRHVLLTYACVKVGCTALFLSPKNSTEGALTVLEAAKCSIWVNPCGYSCPLVDDILQKRSMKVFHLPEVDDLLNAETTESYSYTKSFDEASQTPFCVLHTSGSTGLPKPIAWSHGLIGTMDAVRLLPHIEGDDGLSPWTNNWIDGDRIYSSFPMSHGAGIIMNILLPSLFGLHCIMGPQGVVPNMNLIESLADHAEIDIWSMVPSLVDELGETPDVLVKLKQSKFICASGGPVSPLIGSKVNDVVRVLNLTGTTEGLFMGNLWVERQDWYYFAFHPFSGFEFKEVESGVYEHWVHRNDHWPLFQGIFHTFPDDRSVNLKDLYTKHPTKPNLWAYKGRNDDIVVLSNGYKISPLETEALVTTHPDIKGCLMASHSIGTGKPQAGLLIELEEPTSKNNEVWDSIWAAIERANALSLHKNQVQRDYVAFAELDTPFSRTDKGTVKRRATLEAYADYIERFYSSRLHQDTQFLAIDTSAIASITDAVRHVLGSLSPAVKKATPDDDLFAMGFDSLLVFRAIKTLRVATGLRDLLAPRHLYGSPTLRQFSATLAQLVADMHRKAADGSASNEAVAGNVAEMYRMINLHRTRLSQKVSPFDQMSPNIYLGMKFFYQLREGARFEDVFARLQAGLHRAMTLIPELESKLMPCSKDEIGYKKGDMRISLPPVPCTAAANHKTESSGPQQLRYQDLSAVLPSFAELRAGGFASSGFADDVVLSCPLLPPLPADVFIAQANFITGGCILAINMHHQCFDGTGTIMVMRIWGECCRYVQGDASATCAWLDKESLNRNLPQILYEMEGYAKPAGHVDKNVWGFIDIPDPAETGTECVTEIKNLVTESPLPPAPFFPRNTQWPPIPPADGRHLDSSTFIIPAEMVEQLRQDVLTDPVAGGLISDSDMIQAFVWRAAVKARHHVATQLRNETFETDEMAIVELPIDARPYFSKLLPESYMGNLVVINRPSMPVATLCGTETTVAQIAQVLRAAAVHITPSLVHDAFTLLQSVPDYTKVTTACMGMEGMHTAVNNLMLFQTNAISFGDEFLDDGGVPSAMRVQMDAINAAFRMLVIHPLREDGGIELVIGTLPEELDVLLADGEFTGYCRFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9J9</accession>
    <name>A0AAD8U9J9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/polyamine transporter I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_658231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000259">
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF22">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="198"/>
            <end position="220"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1704668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="534" mass="58339" checksum="5D7565DAF8A4276C" modified="2024-05-29" version="1">MENDPESNPPLDHLKTADQVAQDAQDLAYLGHDQALSRKFSRMSMLFLAISVLGTWSTFAQGLSSGITSGGPVAILWGLVLVLFCNICVAVSLGELCSSMPTALGQAYWIFRLWPSGRFVSYLCAWINTFGWWTLSASQVAFMANFILSMKVLFVPDWSEVSVGWINFLLYLAVTLVVTVANLVACRKDAILPAFNNFVGICFIGLFFIFSLALLISVGVRPNLEFQPASFVFGQWINQTGWGDGVTWFTGLLQAAYGLTAFDSAVHLAEEIPAPRKNIPRIIWLSVTLGAVTGFIFMVVCLFCIQNLDTILNPPTGLPFMDLVHEAVGLQGATVLLSLFIFNGLGQAISIVTTASRLTWGFARDGGMPCSSYFSRVNEAWRVPARALWLQGAIVGVVGVLYMFANTVLEAILSVSTIALTISYGMPILTLLLVGRDKLPPGEFRLGRLGPAINWISVIYCAITTVFFFFPSAPNPAPADMNYAIAVFGVMMVVTLGFWFIKGQYTYLKTDDAAERIIEAQNAEVTTAPVPRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAZ8</accession>
    <name>A0AAD8UAZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758032</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000197">
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
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            <begin position="19"/>
            <end position="263"/>
        </location>
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            <end position="181"/>
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            <end position="210"/>
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            <end position="263"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="200"/>
            <end position="209"/>
        </location>
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            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1708388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="29336" checksum="368487E6447467E0" modified="2024-05-29" version="1">MALLCFFFYLFFTAFATAENRFRRPPGPGLAYDYRDNNVYTIGDVIDLHWDMDYDSARLILWQESVGGGSTLDYIDIVASTSAKSMNWEVSIKDFPNPKLSNLYFFELLGPGKEPANWGVTCHYFNITEAQVTPQPSNTSVATPMPTTEKEGLSSGAAAGIAVGVTFATVLGMGMIGWLLWHRRQARRTPISQDQKHSLDGSQQQQYHYAQTPGWQPELPVEGHGLYEISATSMNVRYEMASHQGMGQAGDADDRPKPFADMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBG6</accession>
    <name>A0AAD8UBG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_586224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
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            <taxon>Glomerellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060505926.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="85389825"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="34534" checksum="BFE167D5D846A9E0" modified="2024-05-29" version="1">MAPNSPPPSISHLISSYPILSILAEYVSALDLFHLAQTNRNHHAHILGSRTIFEKLRSLCLCDGRGLVQRQNFSGRYCPNYWTLLCGLPPMVVGDEEIEVKLYNVKCDEAGALPCRRCGINVCEECRYYDRLLSVEESYVEPRYNWRPLNIMCLCRDCDFQLESDNRKLQLSDTCDCNLCLRWLCIKCEDAQRKETTAYYDTRTKEASGQNNVLNQPEEWGPDEAAETKQLEIYGKWRNFYCPCGAAVAQETVPRCTWCRRRVKSQDEWLDERNQLARLDKPGGSFYVCSSPRWRGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBK6</accession>
    <name>A0AAD8UBK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_711388</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358769.1">
        <property type="nucleotide sequence ID" value="XM_060511602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBK6"/>
    <dbReference type="GeneID" id="85395500"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1710299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="57959" checksum="F1CE313004F7331F" modified="2024-05-29" version="1">MSSMPMELNLPRVVPGGQHISYYVAISAMLVVAWLFQSRRPKLPDMPFYKAAKTKWMFDAETLIRDSYGKFRDTVYQIKATEGLQVLVPARLIGELRSLPEEVLSATEAVDEAMLSRYTNFTLGNHADLLSTLVRCKLSQNLARLVPQLKSELEYVVATEFPNCKEWTPVKFQPFALRAIARISGRAFVGPDVNRQEQWMDISINFAIHVFVAVVKMQLFPEWARPIAQYGVSELRQIRKDVDKATAMLKPIIDERLRDLEMPSYEKSPDDLIQWLVEALPEDEKRDVRSQAHLQLILAAASIHTTNNLVTDCIYDLAAHPEVQDMLREEAHQVLEVEDGWARKESMAKLKKLDSFMKETQRLAGNITSFIRKVVKPIDLSDGTHLPPGTKLLAPQAGISHDERYFENPDTFDALRFYKLRQKSDEDANRWQFTSISDTNMNFGAGKHACPGRFFAGNEIKMVLAYFLLNYDMKLKDGETRPKPMVMVMSKSPDPNAEVLFRRRTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBV3</accession>
    <name>A0AAD8UBV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vitamin B6 photo-protection and homoeostasis-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_588806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359938.1">
        <property type="nucleotide sequence ID" value="XM_060506177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBV3"/>
    <dbReference type="GeneID" id="85390076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="6">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="46055" checksum="95F3933529549777" modified="2024-05-29" version="1">MRQILYDAFLPIGYPDSVTPDYIGYQTFDSLQAFFSTITGLLANRAILQGLGVGDASSSATYALLLTILKDGISRVATIVFAYRFGLVIEPECKRYRYLADIFNDSAFFLDLFSPYFDPWTKVLALVLAEALRAMCGVAAGASKAALSKHFARRNNLSELNAKEASQETAVGLVGLLVGSIVVRYVESREAVFALMVVLVFVHLGMNYLGVRCVQLNVLNQQRATILFKHYMQTKQVLSPAQVASRESIVFWTPVIKDHCGEVITKISFAKSYAHAMTADLKSARVRFVTPEQQSTEKGGQKAHPGFILCLCERGDIATIRILLLGDRSPTEANDINTLMAWYYATVLAHDRALASKTGSQKLLHGAIPVDEIEIGESTEKKLDFKALEEAGWDVNETNLDAFAPRITIGFEDKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBZ5</accession>
    <name>A0AAD8UBZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Linoleate diol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_466514</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361362.1">
        <property type="nucleotide sequence ID" value="XM_060503259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBZ5"/>
    <dbReference type="GeneID" id="85387158"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20612">
        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1114"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1185" mass="133504" checksum="2440F6FF03B5215C" modified="2024-05-29" version="1">MSQAQEQFPKHQPLLTEVSEKLAAARNLVHKSLSAVPPHPEPVPGTAAQQPEPTNLLQDIKKLGFQDFETLADFGITAVQGKIDDNELLLEHLIQLFAKLPRGTVKGKKLEYGLINQLWNGIDHPPMTTLDEKFKYRAADGSNNNIHSPAMGAAGTAYARSAPPITYQTPNQPDPSLLFDMLFARGEEFKPHPNKISSFLFYLATIITHDIFQTDGLSGINKTSSYLDLSPLYGRNQEEQDQVRTKLDGRLKPDSFSSKRVLGFPPGVGVLLMMFNRFHNYIVTQLASINENNRFNRPTGDAIDPEAEAPKKPAEPEGAVPVGHPRYLDWIESQDYKDHTSTPEYKQWASWTAWVKFDNDLFQTARLITCGLYVSIVLRDYVRTILNMNRSPSSWALDPRTNEGKSILRAETPEGTGNQVSVEFNLIYRWHCTISPKDAKWTEKAFREQLKIKGEAKDVKDYTLIEFGHAVRDWERRISDDPVKRDFAGLKRGKDGAFREEDLVKIFKESVEDVAGSYGANRIPEIMKPIEVLGMMNARKWNVATLNEFRDHFGLTRHPTFEDINPDPEVVKKLRYLYGTPDQVELYPGLVAEKAKKPMSPGSGLCGGFTMTRAILSDAVALVRGDRFYTIDYTPKNLTNWGFNQCSYDHNVDQSHVLYKLVFRAFPNSFEQNSVYAHFPLTVPSENKKILEDINRAYLYSWKEPVTKRSMIPVFSHKAVSEILYNQTDFKVVWGDAIRHLVAQPGKEHGKDFCLAGDGKTNTQNRALVRKALITGPWEKEVFKWYTHTTPRLLKQNSFAIRKGVREVDLVRDVINLTNTRFNAALFHLPIKNEDSPWGVYTDQELYVVVATLFQSVFLDADIGNSFKLRTIARELGQGLGKLMSLICLTISKAGLITDIVAKIREGESSLPTFGNHLIERLLADGKDIEEVVWGTIMPVVTANVTNQSQVMALCIDYYLGEGHDHLKTLYKLAHEDTPEADEKLMKYMLEGCRLRGTVAVYREAVTTQVITDYAPCLLDPSDPTSRTPKINDDIDGTKYEVKIPKGQKVLCNLMTAGRDPTIFEAPNEVRLDRPLESYVHYGLGPHWCAGKEISRVAQTSLFKQIVGLKGLRRADKTSTGNGGRGKLKNMPAGAWPGQVGLPVGSSQNGASKKDEPWLGLRTFMTADQSSYWPVPTTMRIEWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC93</accession>
    <name>A0AAD8UC93_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenosylmethionine decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_722215</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361351.1">
        <property type="nucleotide sequence ID" value="XM_060512451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC93"/>
    <dbReference type="GeneID" id="85396349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001985">
        <property type="entry name" value="S-AdoMet_decarboxylase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018166">
        <property type="entry name" value="S-AdoMet_deCO2ase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00535">
        <property type="entry name" value="SAM_DCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11570:SF0">
        <property type="entry name" value="S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01336">
        <property type="entry name" value="ADOMETDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0704">Schiff base</keyword>
    <keyword evidence="8" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1718851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="57163" checksum="6C5C63B19FFB612B" modified="2024-05-29" version="1">MVNPSVPNDYALSPAEATPHLTINHDVAADLDSTNAFEGPEKLLEVWFAPGPESLPASAQPNGLKAVSADTWVTMLDMVNCKILSVLESDSVDAYLLSESSLFVFPHKLILKTCGTTTLLLGLQRLLHIAAEHAGFPFHNAKESTNVKAAATPYRVFYSRKNFLFPDRQQGPHRSWRSEVKYLDDLFEGGSAYMVGKMNGDHWYLYITTPNKTLTPPRTPDEAEEAAAFAARIPTGSVASFSSGFEERSDETLEILMTDLDPENAKQFYLADASAVATDKLHLPQTQAARDDAHQSLGDMSQVHEKAGGEDHVDVFENIGESDLNDGERAATEALTTEGHAIGTVVSEGCGLSSVYPTTKYPGARVDAYLFSPCGFSANGVVPAIPDEDDDSKNEKGGNAAHYFTVHVTPEPNCSFASFETNVPGGQSGRTTAEIIEHVVDIFKPGRFSVTLFEAKGKSANPYGMGDYASRATAVQRLVDPVRGYRRIDRIVHDFEDYDLVFRFYERDDWAGDREARLGEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD41</accession>
    <name>A0AAD8UD41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation machinery associated TMA7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360658.1">
        <property type="nucleotide sequence ID" value="XM_060514683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD41"/>
    <dbReference type="GeneID" id="85398581"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28632">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="68" mass="7172" checksum="33A5B9D038C31421" modified="2024-05-29" version="1">MGGASREGGKAKPLKAAKKAQKDMDEDDLAFLEKKRAEEKARKEMAAKAGGKGPLNTGTQGIKKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE55</accession>
    <name>A0AAD8UE55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_119020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359075.1">
        <property type="nucleotide sequence ID" value="XM_060501141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE55"/>
    <dbReference type="GeneID" id="85385040"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="33687" checksum="E93B61091792EDE6" modified="2024-05-29" version="1">MLIVCEAATAMSSKKECDDLIDSLTTIPLFLKRVKALLSHSQQPLDDAIFCSLSRVRAEVEFLDETIERHLSCLGPVTGKPGAVEADVLFVRLSPISSTVTRRQEASDVPLNSTLTAENIASLTRNDCAAGRECRTDPIPSFEVGRGAEKRRLPGPSHDIVEIPRRFLGLIPPSRDVCFVDLTTEHSPRYGPDLDTASMIDVSSNRNLDSATEPRPNGKPSSKSIVKLIDRAVEHAHVGWLSCRDQAQFRERLGQFCPGRYVDDVVFLAMLQLVCCTSTLQIIDPLLVRFTEPFLTSGAFAFAKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH51</accession>
    <name>A0AAD8UH51_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_587426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360575.1">
        <property type="nucleotide sequence ID" value="XM_060506037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH51"/>
    <dbReference type="GeneID" id="85389936"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="33"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="39178" checksum="6F2E39A6B85F60DB" modified="2024-05-29" version="1">MEVNWITRPNLLGMATLGITICLGSISFVVFILRLWARHKTRATGTDDYLMGIGVAIYLACCVFTSIAVYAGMGTTDSRLKEWNMWLVFFQITYAWSLPFIKASICFTVFRITNRRRYRTILWAVMIASGLSTTIGFIAVVAVCRPVEYTWDKSVDGQCAPQNIITTISYMISVLAIVTDWTCAIVPTVVVWGLQMKSRVKVSVCAVLALGAIASAATIVRLPYLQYYNQVENYLHNISNIVLWSILECGIGIIAGSLPSLRRLLKFWLDKSSKGSYNNTGSNDLNARQAGSNGIRMNNLSGRGMTVSNCQSGPHDNWAQLDDDSDSQKHIIMKTREFTVQYERDGQSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHD6</accession>
    <name>A0AAD8UHD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_634225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360725.1">
        <property type="nucleotide sequence ID" value="XM_060509084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHD6"/>
    <dbReference type="GeneID" id="85392983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="89" mass="10235" checksum="DA41668524CBAC4F" modified="2024-05-29" version="1">MFIAYVSYKDQECPCPGPWTCNLLLGVRVIPDLRKRHHSFTNMSTSSEHQRPASHTWLSWDSSHVVMSQHRLQRQPGRHPTPAEDARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ44</accession>
    <name>A0AAD8UJ44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_583184</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362436.1">
        <property type="nucleotide sequence ID" value="XM_060505626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ44"/>
    <dbReference type="GeneID" id="85389525"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="15"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="54905" checksum="9B628A5FC76667D5" modified="2024-05-29" version="1">MASLKLGSTLSHALIFCEAIFSICIISYDAAMVNNLNAVVPYRQHFKLNSDMDGLNAAIISAGCIIGAPVVGHLVDRWGRKAGLGLGAMSIIIGVILEASATKVAQLVCGRFLIGFATLINGSVPPMWIMELGTPRYKSMLANAVLVSAPFTAFFTTCIFLGIWDNQSNWAWRGIMLVKAVPSVLALCLLPFVDESPRWLFHKGRTEEAIEILARLHANGDRQHPLVIAETQEIMGTLKHEEQHNGGWRELISPASNLKRFIIAVLINICYQIIGANVILYFSSFLIAGLGIENRGTIIQVNMGLLLWNAFCSLAGVFVIDKIGTRKALIFGTAATVVLFAILSSLSYLAGQYPNNHGYAIGAIAVVGLFLLAVSCSWMLLAYTYPPEILKYSQRSKGVAISQAIGYAFSFLNLYTAPIAMEKIGWRYFAINGGWNLAILATAIWLFVDTKGRTLEEMDEIFDGTGHANGVIIGTDIAQSFELDTTGEAGNIVKKKPTLASTDTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJQ4</accession>
    <name>A0AAD8UJQ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_700259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364573.1">
        <property type="nucleotide sequence ID" value="XM_060511427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJQ4"/>
    <dbReference type="GeneID" id="85395325"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042239619" evidence="1">
        <location>
            <begin position="21"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="581" mass="63367" checksum="DDFEE47673CFB4B7" modified="2024-05-29" version="1">MVRVNSAALLGSAIVGLASAAGAGTKAEYASGAVHHRIMGIKMAQWEEEAAAGLMDSAKYPELGYTPCVDGFAAAVPGDFNNTFRCRNIDLYHFLSHEQLGSWGGRGSSSWGWTSADGREFVAIGQYDGTAFAEISKEGKLVYLGRLPQYDSIGSNWREIRIVGDLAVIGSEAIKHGVQFFDMKKILDLDPANPKNFTQAELTGHWDELPVGRTHNIVVNQELNYAIACGSVGGNATIRVRDNLPCRGGLIFLDISDPTNVTSPGCAAGDGYVHDAECLVYRGPDTRYYGRDICYGYNEDTLTIYDVTDKTGNVTNIISISDYPGAQYVHQGVVNNETWQEYIFLDDEFDERDAKVGPMTQGLPTTHIFDIRDLEKPVYTGHYAGKTRSIDHNQYIVGGYLYQSNYGNGLNVIDVSSVTKDPTGASICEAGFFDIYPEDDEEVGGGKVQFAGSWSSYANFKSGFIFVHTIERGSFVVKMTSKECPKAPVCNADNCLRALRASSIPDRLEESVEFCGNFTQRLNTDDELLPEYATSACVENKNKSPVERVSSACACIPTPVVPELPRTTTRPPVPTVLPPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJU9</accession>
    <name>A0AAD8UJU9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_627877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362913.1">
        <property type="nucleotide sequence ID" value="XM_060508664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJU9"/>
    <dbReference type="GeneID" id="85392563"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042112388" evidence="1">
        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="101" mass="10425" checksum="2EB1378CDE046371" modified="2024-05-29" version="1">MMFLHSLIVGVFAIAVTAAPAPTPQGDPAQDRCAGVACPENSYCKVFDFRLEHPVGCQSNGTVPADAETCGSVICPTGTTCCNSPCGVCAKPGETCLQWVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL20</accession>
    <name>A0AAD8UL20_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363734.1">
        <property type="nucleotide sequence ID" value="XM_060514337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL20"/>
    <dbReference type="GeneID" id="85398235"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF6">
        <property type="entry name" value="OXIDASE USTYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="290" mass="32827" checksum="BDA4EB62C37C8F72" modified="2024-05-29" version="1">MNRDSSNVGAQLLAAEVNNLEHGTLCSRCEKAITGENSSGFSYLKLFLVFILCQVPILGLSLSACHNYQSNNAAATSKGIDQQDYFTLESYNSTEKLYDIVDAADKSPEADAFWHELQKTDGIVSVTSEWAKENALPQTVSHPDDPVSKIYQINVFHALHCLYRIRNRLTSNIPLEKWPRNDIHTMHCVDHIRNDLMCHADISLSGSGEYVSFNSHSHHQKCRDLGALQRWAKRHSWAGYKEYLEGVVGYDFNEAERVNMATAGKGHWNKAQSTLDKETEKIELWFEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL83</accession>
    <name>A0AAD8UL83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_753600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363441.1">
        <property type="nucleotide sequence ID" value="XM_060514367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL83"/>
    <dbReference type="GeneID" id="85398265"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF157">
        <property type="entry name" value="N-ACETYLTRYPTOPHAN 6-HYDROXYLASE IVOC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="556" mass="62911" checksum="6326180AF80D2469" modified="2024-05-29" version="1">MSNIEVLINTLATDAAVIKEPNNTISSLVGIFPKADFLWSLGNLGETNRGELARRLFFIWTGYVVLRCIYNFYFHPLSKIPGPWLAAMTPLCDFWYDAVKNGNYLWEIQKMHEKYGPIVRINPNEVHIDDPEYYQNVYVGGTHRINKDSSTVAGFGVPASVAATVNHAQHRSRRGYMNPYFAKRSIVSMEPQIHERITAMLNRLDGARKEGAKISLDLAFSAMTADIITQRFFGYHYDYLSIPSLVSPIREAFKGVSEIFHWTRFVPWAIKYLKKLPIPVIRLVLPPVAELLLLQEDIKINIKNKLASENNSLQSKSIIIEALGNSHVPAQERTMERLVDEGQVIIFAGTETSSRSLAVGMFYLLADKSLVTKALDELSKLDHIPDEELTMKDLETLPFMTGIVKEAIRLSYGPITRLPRVFTHETLQYKDHAIPPGTPVSQSTYFVHTNAKCFVDPFTFNPDRWVEAAKAGFPLERYLTSFTKGSRQCLGIGLAHAELYLTFTRVLRNFDMDLVNTSIVDVQVHNVLIIGQPKLEKDKGEGQGEVEVMVTRKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULD9</accession>
    <name>A0AAD8ULD9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase III, subunit Rpc31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_528824</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363738.1">
        <property type="nucleotide sequence ID" value="XM_060503312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULD9"/>
    <dbReference type="GeneID" id="85387211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11705">
        <property type="entry name" value="RNA_pol_3_Rpc31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000777">
        <property type="entry name" value="RNA_polIII_C31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="17121" checksum="2E85E9062C5FC107" modified="2024-05-29" version="1" fragment="single">MSRGGRGGGRGGRGGRQGPQLSWDNGEHAPDTRPSELFPAYAIPTAKPVTDHEQANVNAFLLFRRQFQDGPLYTRKRTWGMDPTNTRKFYGQEQVNAKYGVRTRATADPFNAVPTYSQKFTRPERALPDFGGRPFCKEFFPLELHETLDGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMB9</accession>
    <name>A0AAD8UMB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_579572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364026.1">
        <property type="nucleotide sequence ID" value="XM_060505256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMB9"/>
    <dbReference type="GeneID" id="85389155"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="307" mass="32255" checksum="A4632A4D3D679AB1" modified="2024-05-29" version="1">MSNDNSNTNQNTQNNPNEMHRQRRGSVTQQAIAGLFRSNSTSNGGAFPGTSDAQRRRLSVTTGLGLTGTSPTGASAFNSLRRGSLSTNSNDSIDENAIDEEEIPPNARTAPTTPFTRRMSFGAQAMRTMRNGGGSPGSNGNELSSASATPVPSTPAALDRRSSVHSRRGVGSVASSTSPANTSSIAAALSSARRRSSSTVQASIAHKQRSSSDVFSRPDQGFNWSEQLRSRAESSVQGPRASFSFGSGLSSSPPRGPGNGAAHDRQKSVSDMPAPPAQAAAMKPKAPERPKPDAFQERILKGDFYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMU7</accession>
    <name>A0AAD8UMU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphodeoxyriboaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_779370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364503.1">
        <property type="nucleotide sequence ID" value="XM_060515516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMU7"/>
    <dbReference type="GeneID" id="85399414"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="24460" checksum="E119203A5B3F482F" modified="2024-05-29" version="1">MIDHSLLHPTMTDADVPEGLRISKKYGVATACVSQELQGSGVLVCPVIGFPHGNSTTEVKVFEANQAAAAGGKEIDMVANIGKVLRGEWAYVAEEIRQINDVVVRHGAILKVIFENDYLEEEHVIRLCEICSDIGVALQPNGLYTYKGATVRHLQLMREHSKPEVQVKAAGGIRTLDDLLHVMSLGVTRIGVTATVAIMEAAVTRGITDQPTEVEFKPISGPSTGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN04</accession>
    <name>A0AAD8UN04_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-channel protein CCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_575816</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Voltage-gated, high-affinity calcium channel that functions together with MID1 to mediate calcium entry into cells. Required during conditions of environmental stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365867.1">
        <property type="nucleotide sequence ID" value="XM_060504857.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388756"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:calcium ion import across plasma membrane"/>
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        <property type="entry name" value="VDCC_alpha-1_subunit"/>
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        <property type="entry name" value="Volt_channel_dom_sf"/>
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        <property type="match status" value="4"/>
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        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="EF_HAND_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
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    <feature type="transmembrane region" description="Helical" evidence="19">
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            <begin position="465"/>
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            <begin position="527"/>
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    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="668"/>
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    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="740"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="771"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="802"/>
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    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="864"/>
            <end position="883"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="938"/>
            <end position="963"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1173"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
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            <begin position="1206"/>
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            <begin position="1990"/>
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            <begin position="1"/>
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            <begin position="28"/>
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            <begin position="93"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00057587"/>
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            <dbReference type="ARBA" id="ARBA00061395"/>
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            <dbReference type="ARBA" id="ARBA00067459"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000256" key="19">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
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        <source>
            <dbReference type="EMBL" id="KAK1725812.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2096" mass="236223" checksum="92950040F1C48DC1" modified="2024-05-29" version="1">MQSNNPYSYEMSSRQDESSGSGREGLQADSQAESQRGRQGQPQMSANGLGLSTYWEQPYAQSNSSGGPDSPIDASALQFALPPDINQPPPFPRLNSPSLDSLDRPSPYFEEATNPDYYEDRVPLTSRAQPISGSLSANVGDAQPRDSFQTVSDIDNAPPRTRDARSLGYDLEPGGRRPSYGATLSPGGEQRRSRSPSTTGALLRAGSIMRAMSQRVVNISGEGELVDHRTSRSRSPSPAPDRRQQLHNSAQMFTDTSYHSNLFQVPEKGPEAENVFADPPPSMQQRVPMQNPLKGKSLGIFPPTHPIRTKLCDLLVHPFTEPFILILIILQATLLAVESAPDVFTNPRPASWGVTWIDWAILVLFIIFTLEFIARILVSGFLLNASEYSTIDRQKGVRAAVVDQYRNLFQPQRQKSVKAPRQQIHLGPSAFQRSFTIMQGQTLPQTVEEQQRYQLARRAFLRHSFNRLDFLAVVAYWISFALRITGVESEKHLYVFRMISCLRILRLLALTNGTAIILRSLKKAAPLLVRVAFLITFFWILFAIIGVQSFKASLSRQCVWLDPTDPTNKEKSFTNDMQFCGGFLNNDTGESMPWVMMENDGILDNFRNGSKAGKGFLCPRGSICLQQDNPFNGTVSFDNIAQSLEMVFVIISSNTFSDVMYYTTNSDYLPAALFFGAGIMILMLWLVNLLIAVITSSFQVIREESRASAFTAPEEPPAQEPMDEPPQKVPALQRIYDKTFLLWIAVIAFGLMAQCFRSSKMSKERGQFIDSAEVAVTILLDIEIIIRCAAGWRSFHKSKRNLIDAGLAIITTIILIPPIRNSGETYAWLTVFQIVRVYRLVLAVPMTRKLIVMVLGNSNGIANLMLFVFLITFLMAILAAQLFRGEIPSHSDSGDLNEVSFFTVYNSFLGMYQILSSENWTSMLYNVTSYLNEHDTGWIGAVFLIGWFILSFLILVNMFIAVIQENFDVSEDEKRLEQVKAFLQRKELGKSAGNLTLSNIFTFGKARRRKDPLDYGPAMMEMLLKDAVVHEFLDDAADMPQDTPNEERSPTRAQTHHVGEVRPGFLSSMWGKFKSMFSSKDPNPFYSNLRFDGPNDTLDPRQMARQAVSATSARKKAQRDYLARHPNYNNSLFVFTPNNPIRRFCQRIVGPGRGNERFEGVEPNKIAWYTSSAFIYACIVAMVVIACVTTPLYQKQYQAEHPEFSITFWYVWTDLAFATVFSIEAVIKVVADGFFFTPNAYYRSSWGFIDGIVLITLLINVGTLLANDGAVSRAIGAFKALRALRLLNVSDSARDTFHSLIVVGGWKILSAAFVSISLLIPFAIYGLNIFNGQMVKCNDGDDSIMLISDCFGEFNNTPFNDDWPMLAPRVPSNDYFSFDDFAASLFVLFQIVSQEGWTDVMFAAQAVTGLGNQPKDLNRQGNAMFFVVFNLLATVFVLTLFISVFMRNYTEQTGVAFLTAEQRSWLELRKLLRQISPSKSSYNESEKTWKKWCHKRAIEKRGKWYTAVTYVLICHLLLLLLEYHGEPQWWTDSRDGLFLAFTLVYMANIAIRIIGLGWARFRRSSWDLYSLVVVTGAFVSTSVLIISRNSDTYVQLHKFFLVAILLLLIPRNDALDQLFKTAAASLTTIGNLLATWLVFFLVFAIALTQAFSLTRFGENEEANINFRSVPNALILLFRMSCGEGWNQVMEDYATIEPPLCVDNADFFNSDCGSKPWARFLFVAWNILSMYIFVNLFVSLIYESFSYVYQRSSGLAAVDRDEIRRFKEAWRSVDPAGTGFISKDAFPRLLGELSGVFEMRIYDADDSVRQILEDVRNDVSTSGARHMSIASASNYSAGIDIQRLNRRLAQIDVVKVRERRRRFNIFFEEVMVSADPDKGISFTSVLMILAHYNIINDSKSLKLEEFLRRRARLQRVEEEVRRRVVLGFFDTLYWTRKFKKHIDMRKSARMTAIPQLDIPHILVDDDDTRHKSSPVAGTGQTRSALLTVEDAHKSAHNSWSGPGPTDTSDGDYQHPLSFPRSGPTTPSHQSTHSAFSFELQEGGQTSAQSSRRGSAVTPQSPVSPAQVSNMLDDSIWLESIRRTATVRKSVRKSDWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNB3</accession>
    <name>A0AAD8UNB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364279.1">
        <property type="nucleotide sequence ID" value="XM_060508418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNB3"/>
    <dbReference type="GeneID" id="85392317"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041916768" evidence="1">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="14934" checksum="6F54AEF4D7621698" modified="2024-05-29" version="1">MQFSSFIACLVMAPLALAIPAELPSAEGALALRAAENIEIPKDLPDDWKTALEAYFKDTDLDLENRDLDKRSNVPFMHCGWRRFFSCLGSVTPGGVTCMWAIAARGLDVKEDSKCSAAVVATILSASNNCKLCVNGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNG2</accession>
    <name>A0AAD8UNG2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_572195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367647.1">
        <property type="nucleotide sequence ID" value="XM_060504479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNG2"/>
    <dbReference type="GeneID" id="85388378"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF5">
        <property type="entry name" value="ALPHA-RHAMNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="1">
        <location>
            <begin position="282"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="2">
        <location>
            <begin position="617"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="739" mass="80092" checksum="205011E24AF7FFA1" modified="2024-05-29" version="1">MPNLWTSLFAFVTGQWGLINPDWRSSSTPRDESIRHEDVPSWHQYVRASESRTIYPARVIPDLTRGDVSNPSGLINGEGGHTVFTRGSAGDEAPSVTVDFGQNTVGILSISFAGSSSSRPGIRLAFSETLQFLSNVSDFSRSYNGDTITPGSDQIAVAKDAYTWTAKHGCQYPNEGSKGQVCADGLHGFRYLRIYLDALPSDTPHTAPQGQVNISSVSLALSAYHGTPDTFKGWFECSDEELTRWWFDGVYTNDLCVDVFRGAEDAEPRGAASETLEGKVVLHDAPKRDRDPYVGDLAVAALTGYVSHGKGTLSEASRNVLVDLAVHQRSDGWIPPASIMNYTLPLFDYPLWWVVCSHDYVWYTGDVEYISTYYANLVAVLDGWYVSVTDPETGLVTKGLNGTSGYGDYAFLPRQGPVTYYNALYVLALRRAAEMAAEIDGKEGDAERWAARADDVASTLARRNFDAARGAFWDGTDGNGEFVAAHAQDGNSLAILAGGVVDTSTARGILAYYAGAASRTYGNAFYDSDAVGQGFSQRVYAFISYFEMAARFASGVGETAVEEMRRLYGWMAGQDPGVTFWEGIGGPDGRPYEDGFTSMAHGWSTGVVPLMSGHVLGVRPTGPGFRTWSVVPEVSGLKWARGVVPTPEGKGIRVEWEDFGTGEGVQFRIVVWAARGTRGVVGVPVRARDVVVDLGGTVVYRGRDGARARFEGEKVWVEVEGGDGVDGVAIFVRLVQEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNR2</accession>
    <name>A0AAD8UNR2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_650226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366793.1">
        <property type="nucleotide sequence ID" value="XM_060510355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNR2"/>
    <dbReference type="GeneID" id="85394254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="122" mass="13228" checksum="16F92D20D66A73F4" modified="2024-05-29" version="1">MAAKTVERLAMSPSGSAVHFPLRLFISTLPHFLDPRRDGAGAGRKGRLEATRRRVAPGQFKHPPRARKMSMGYEMGVTVWLGSLLGAHHGRGIVPGSVEGRSQAEHLLILGPPDYPALIKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP44</accession>
    <name>A0AAD8UP44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2OG-Fe(II) oxygenase family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_717371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368037.1">
        <property type="nucleotide sequence ID" value="XM_060511941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP44"/>
    <dbReference type="GeneID" id="85395839"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042149611" evidence="7">
        <location>
            <begin position="23"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="8">
        <location>
            <begin position="80"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="310" mass="34324" checksum="E72EDE951898DBC5" modified="2024-05-29" version="1">MISYVIALVAFLIFFSDPLVDFFSPSSTSGSGRSSTSRNRVARSPRPQMNESLLAIEHPNATALSCPPDDYSVRIFSKEPLVLYIEGFLSVEERKHLLEISNPIFEPSTITHNGANTHRDTSIRSSDVALLPRDDTVRCIEARARALQGWREDLWIERLRTQRYVEGGHYSYHFDWTANRGGWGRVSSMMAWVDARGEDENEVPPGTGNGDGLVGGGTEFPLLEVPGLKKEAWCRFVGCVGRNGGEEKKMGGEEEVKGTTFKPVPGNAVYWENFRADGSGAGYDETWHAGLPVKKGVKVGLNIWSTGRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR35</accession>
    <name>A0AAD8UR35_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA mismatch repair protein MSH5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MutS protein homolog 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_618577</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365871.1">
        <property type="nucleotide sequence ID" value="XM_060508081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR35"/>
    <dbReference type="GeneID" id="85391980"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03281">
        <property type="entry name" value="ABC_MSH5_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001067">
        <property type="entry name" value="DNA mismatch repair protein MSH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="12">
        <location>
            <begin position="130"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="13">
        <location>
            <begin position="499"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="764" mass="83248" checksum="D272931ABAFEBBEC" modified="2024-05-29" version="1">MDRLMNLPIATSEYALVTNTVFGLSNRGLQGPGDNCQDVKTMRLGSFVDLESVTSIGCAGAVLCETLRLQNVEGAPEDTERTFGVSLQMFALTDFMFVNADTLSCLQIFQSELHPSNLISGAGKAASGSKESLSLFGLFYPLAGTPQGKARLRQLFLRPLINIDMIRERQATISVFLQPGNEEAFTSMSKELRKVTDIRETLAQLQRGAAESPAGCASIERGVWWTLTRFSLHVLRLRDAILQLRNSNGLFIIQKMVQVVAVDKLTAIIDLIGKVVDFEETKANSRIAVKLHVNTELDGLKQTYQGLESLLNEVSTTLSLELPTWARKFVTGCVFWPQLGFLTVVPLLEGTRAGYEGQGLPGDLWEQRFTANDNVYFKNNLMLELDEHFGDTYSRIVDLEVDILHGLACTILEHEATLSRVSDVCGELDCLVTLASGALKYGWVCPTMTEDNIVSIYDGRHPLQELAVPAFISNDCSLVGGSANETRTPTSTPNNDIGASTLIITGPNHSGKSVYVKQVALIVYLAHIGSFVPAASATIGLTDQILTRISTRESVSQAESAFGTDLRQVAFLLNCATRQTLVAIDEFGKGTAADDGAGLMTALIDHFSTLGLQSPKVLVTTHYHEIFEGGYLSERPGISLAHMEVRLDIEANQMEDQVVFLYRLVPGRSTSSFGSRCAALNGIDTAVVERAEAIVLLLARNEDLGVVCARLDAEDEARLEEAENVARQFLRISLDGPGESQSRSRGISSTLVILQDLLMPAVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URE9</accession>
    <name>A0AAD8URE9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Snf7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_610098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368143.1">
        <property type="nucleotide sequence ID" value="XM_060507574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URE9"/>
    <dbReference type="GeneID" id="85391473"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF5">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="164"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="210" mass="23482" checksum="7EF8FCD68588628F" modified="2024-05-29" version="1">MGGNTSKVTAQDKAILDMKLQRDKLHQYQRRITVLTDKETAIAKQMLAKGDKPRALLALRRKKYQESLLQKTDAQLEQLEKLTSSVEFAMIQKDVVFGLQQGTKVLKEIHSEMGGIEHVEKLMGETADAIAYQREVSEMLGGRISVQDEEEVEDELAALEASVAAEDAMRNPPTLPKVPDTKLPTPQGEEEEEEPEAQQPIRTRQAMLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ3</accession>
    <name>A0AAD8URJ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_612137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367592.1">
        <property type="nucleotide sequence ID" value="XM_060507703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ3"/>
    <dbReference type="GeneID" id="85391602"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="226" mass="24828" checksum="EA92A3DAE7C99102" modified="2024-05-29" version="1">MEEQLQHPKVTEREGSPSWSQLRTVRRARDSPHDVPCGEECLVYPKGKTNHTPTGIMGKITRYLELDFESRPSKDDVWMERKGRKRRRGGRHRRCPRPNQFHPGEGEGLEDMEETMEGELVEPVEPGARGAGGGGEVGRVYPPAAVCGEEVRPADQVAAVWGGFDNPAAGPAIEEATPVLLCPGQARAGEVRLPGAVEVPRGEGADPPRRWGAGSGRIATSRQWRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URQ7</accession>
    <name>A0AAD8URQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_609738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368323.1">
        <property type="nucleotide sequence ID" value="XM_060507547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URQ7"/>
    <dbReference type="GeneID" id="85391446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF26">
        <property type="entry name" value="FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041984519" evidence="1">
        <location>
            <begin position="19"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="50236" checksum="CA7B8D8DE1A9EF7F" modified="2024-05-29" version="1">MRSHLLSLCAFSATLISAAPSGLGCYDESAFKPEDIIQRDVLIVGGGATGTYAAVRLRDQNKTVAVVERADKLGGHVNTFRDPATGAPIDYGVQAFIQNDQTTQFFERFNVQLNASALSPFPSKIVDFKTGFVVPNATAVDPNTLVGPLANYLFATLNFDFLAEGAYDIPENVPEDLLLPFGQFVQKYNLTEVVQVVWIFAHGVGNLLETPTLYVLQNFGQPHLLGLSSGYLYAPGGNQQVYDKAGAFLGSDVLYSSTVVASKRADDGVKAVVATATGRKLIKAKKLLITIPPTVQNLAPFDLDDSETSVFNQWENVPYYVGVVSDSGLPDLTNFLNVDITAPDALPSKPFVWRLETVGVPGYQTVKVIGEADSTKAQGLVTDAVRKVGASSNSTSATGGEFAAWEEHSNLQLHVSTEAVKAGFYRDLYALQGKRSTYYTGNAWCSDYSPLLWQFTEKRILPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URS4</accession>
    <name>A0AAD8URS4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_774521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366588.1">
        <property type="nucleotide sequence ID" value="XM_060515424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URS4"/>
    <dbReference type="GeneID" id="85399322"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="34128" checksum="C8F14CCDE5173B92" modified="2024-05-29" version="1">MKNLYGHGHNATKTDWYSIWDPPNTAPQLFWELDKKHHNFLRERLASAYSMSSVHKYEVHIQACLDFLVRKLKKYAQNGETVDMAIWTNAFTFGVVGELGYGSQFGHLEQEKDAGIAAKSNSSGAGADTTSIGMRTCLFHLAAIPEVQAKLREEIDTFYDVNDLKAPMSYLEPHKLPYLQAVIKEAIRLLPSIVFQLLRHTPPDFKVRGIKVLVNTTIGISPMAQNRDWVQMQTSSARADGENEDKTRYFDCSTMTFGGSGPIMCIGSNIALVELHKFVAQPVHNFDFELVNKNIPWRIKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URU7</accession>
    <name>A0AAD8URU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_223983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367305.1">
        <property type="nucleotide sequence ID" value="XM_060501757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URU7"/>
    <dbReference type="GeneID" id="85385656"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="15288" checksum="BA078E6A2CC797C5" modified="2024-05-29" version="1">MCSYKSIPSSLAILGCSLLLHYLPTYLMHICRSFHYLEPSTDCLQPSHTSCFFVGKLKRDLPAFNSAAPYPSWAADRSSIIHNAAPLGACPVFSDRQAVRCSKGLIQPGFERSPPPLHCLPFESVPAVTGRLCHQRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USH7</accession>
    <name>A0AAD8USH7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sedlin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_610884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368057.1">
        <property type="nucleotide sequence ID" value="XM_060507617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USH7"/>
    <dbReference type="GeneID" id="85391516"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18459" checksum="21F98516A4F7A923" modified="2024-05-29" version="1">MSYYFAIVGTQDNPLFEYEFGTSKQGGDGQSRFNEQVRHLNQFILHSSLDIVEEVQWAQGQMYLKIVDKFFNNYVSCFVTAGNVKFLLLHQPSAPSTTASSRSSTAIGANPTSPATEEAIKNFFQEVYENWVKAIMSPFYRVNMEVKSPVFRSRVAAAGRKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTF2</accession>
    <name>A0AAD8UTF2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_729267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1727001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367056.1">
        <property type="nucleotide sequence ID" value="XM_060512816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTF2"/>
    <dbReference type="GeneID" id="85396714"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="447" mass="49259" checksum="606AB88A16EC646F" modified="2024-05-29" version="1">MSSAPKTSTTARSTLAAAAMAGSTKRKRSAIACTACHQRKVRCNLAAQGPPCTNCSEDGNVPCRVYGSRAPPDVPPPPPPPPPPISPAMPSPSSSSQHLPGRGDEHSSPDLDPGLGPSSERQYRPTSIENLLCTAHDPSYAPGTPNAPVLYYIGLFSISSGNEARPLKTDVLGPVGESAGMALLFDICYPSRPLPGNFYIIQRQRRYFPPAHITSPLMARPLPEPAALHDMICCYFRYLHPYLPVIDAGRFIPAFANQPSSISPLLLWSVLFAAATFVKPEHWQAEFRTRKEFQEDIYRHAKCNIWARIWWSLYSREVWLGLGFGRPLRINSEDCDLPMPEPAAVLNDINSLPDTLRQSFIPREFETLYSPGNAEQSLRGVDGRNTTPVITSQCPQDLPWDRVNCSSPAIPHPVKAKLNNSSRGKQHPIARDGQVHRSRFGHHEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTW0</accession>
    <name>A0AAD8UTW0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Acetyl-CoA carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_613984</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367084.1">
        <property type="nucleotide sequence ID" value="XM_060507792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85391691"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.460.10:FF:000001">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000010">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0092">Biotin</keyword>
    <keyword evidence="8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="17">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="16">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="15">
        <location>
            <begin position="350"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="18">
        <location>
            <begin position="1177"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="19">
        <location>
            <begin position="1519"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1727029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1938" mass="217242" checksum="F28E8C9EB7CC1108" modified="2024-05-29" version="1">MEDAAVRLGRLVGYVSAGTVEYLYSHADDKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPLHRIRDIRLLYGVDPRTSTEIDFEFKQEGSEKTQRRPRPKGHTTACRITSEDPGEGFKPSNGVMHDLNFRSSSNVWGYFSVSTASSIHSFSDSQFGHIFAYGENRAASRKHMVVALKELSIRGDFRTTVEYLIKLLETEAFEDNTITTGWLDELITKKLTAERPDPMLAVVCGAVTKAHLFSEECMTEYRTSLEKGQVPSKDILKTVFAIDFIYEGFRYKFTATRASVDSYHLFINGSKCSVGVRVLSDGGLLILLDGRSHSVYWKEEVGATRLSVDGKTCLLEQENDPTQLRTPSPGKLVKYLVENGEHVKAGQPFAEVEVMKMYMPLIASEDGLVQLIKQPGATLEAGDILGILALDDPSRVKQASPFVGQLPVYGEPVAVGTKPAQRFDLLHNTLKNILLGYDNSVIMAATLKQLIEVLRTPELPFSQWNAQFAALHSRMPQKLDAQFTQIVDRAKSRHADFPAKALAKAFQKFLEDNVAAGDADMLKTTLAPLTDVLNAYSEGVKAHELTVIKDLLASYIEIERLFTGYGTQEDSVILKLRDQNKDDIRKVVQTVLSHSRVGAKSSLILAILEEYRPNKPNVGNVAKYLRTALQQLTELQSSRTTSKVSLKAREIMIQCSLPSLEERTAQMEHILRSSVVESRYGEAAWDHREPSLEVIKEVVDSKYTVFDVLTLFFAHEDPWVSLAALEVYVRRAYRAYILKQIEYHSDETDTPLFCTWDFALRKIGQSEYGLPLQSAAPSSPATPSGSGGSFDFKRIHSISDMSYLNHKWDSEPNRKGVIVPVKYLDDAEDLLGKALETLTVSEKARKRSTPGLIPDLSGKRKPAAPKVDSDELSAVINVAVRDAESKSDQEILSRIVPIVEQFKEELLNRNVRRITFICGRNDGAYPGYYTFRGPEYVEDDSIRHSEPALAFQLELGRLAKFHIKPVFTENKNIHVYEGVGKAVDGDKRYFTRAVIRPGRLRDEIPTAEYLISEADRVINDIFDALEIIGNNNSDLNQVFINFTPVFQLHPQEVESSLQGFLDRFGARAWRLRVAQVEIRIICTDPDTGVPYPLRVIITNTSGYVVDVDIYAERKSEKGEWVFNSIGGTKEKGPMHLLPVSTPYATKNPLQPKRYKAHLMGTQYVYDFPELFRQAIQNSWTQSVKKHGALGAQQPKSGECVSYTELVLDDKDTLQEVNREPGTNTCGMVGWIFNAKTPEYPKGRKFIVVANDITYMIGSFGPKEDNFFYKCTELARKLGIPRIYLSANSGARLGVANELMPYFKVAWNDANKQDNGFKYLYLDDEAQKRFAKDVITEEISEDGEKRHKIVTIVGQEDGLGVECLRGSGLIAGATSKAYNDIFTITLVTCRSVGIGAYLVRLGQRAVQIEGQPIILTGAPALNNVLGREIYTSNLQLGGTQIMYRNGVSHMTGTDDFDGVSKIVEWMSFIPEKRGSPIPVSPSTDGWDRDVVYTPPQKQAYDVRWMIGGHPTDNGGFEAGLFDKDSFVETLGGWARTVVVGRARLGGIPMGVIAVEARSVENITPADPANPDSIEQITNEAGGVWYPNSAFKTAQAINDFNNGEQLPLMILANWRGFSGGQRDMYNEVLKYGSYIVDALVKYEQPIFVYIPPFGELRGGSWVVVDPTINPEAMEMYADVDARGGVLEPEGIIGIKYRKDKQLETMARLDPVYASLKKQMTADLPKEQADEIKKKMTIREKQLLPVYSQVAIQFADLHDRAGRMKAKGVIRDQLEWVNSRRYFYWRLRRRLNEEYLLKRMSSTVLTSTPGNDKSKAPETRSRNLQLLESWSGVVNFSTADREVAEWYEANRKSVTDRIETVKADNLAADLSSVLRANKSAAMRGVRDVIRTMPPEERDQLLKYLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUC3</accession>
    <name>A0AAD8UUC3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_178309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367904.1">
        <property type="nucleotide sequence ID" value="XM_060501510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUC3"/>
    <dbReference type="GeneID" id="85385409"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="9944" checksum="C054D773BDC725C1" modified="2024-05-29" version="1">MDKLEQHAGAASQWPTLICFVSCLATFTPSSPPNTTLPPHHHFLTNLGRFAFFWRLLLSSLLTTCPIDDEDRVLRTHKILVTDHSCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUM5</accession>
    <name>A0AAD8UUM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cral trio domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366650.1">
        <property type="nucleotide sequence ID" value="XM_060504695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUM5"/>
    <dbReference type="GeneID" id="85388594"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.525.10:FF:000013">
        <property type="entry name" value="Phosphatidylinositol transfer protein PDR16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="132"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="368" mass="40275" checksum="9DC1E91B82C18087" modified="2024-05-29" version="1">MASVADQTPASTTAAAGLQEKATASGPLKTPIALPIPASSTPAVPALTADQQTKYDGLLAQARAWTEVKCTTAAHVAKSGPLTDSERQWLTRECLLRYLRATKWSSKDAEKRLLETLAWRREYGVEALTADHISPENETGKQIILGFDKERRPCHYLNPGRQNTDPSPRQVQHLVFMLERVIDIMPAGQEKIALLINFKTSKSRGNTAPGLGLAREVLHILQTHYPERLGKALIINVPWMVNGFFKLITPFIDPMTRDKLKFNEDMRQYVPEEQLWTEFSDGKLEFEYDHSVYWPALNGICKEKHDARTARWIAGGKQIGESEDYLGGAVEKGVGAEAAAPAAAAAAAAEAAPVPAAAETPAEVKPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUQ1</accession>
    <name>A0AAD8UUQ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLAC8 family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_615690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366695.1">
        <property type="nucleotide sequence ID" value="XM_060507915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUQ1"/>
    <dbReference type="GeneID" id="85391814"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="170" mass="19397" checksum="952C7953D233C6AC" modified="2024-05-29" version="1">MPRSQPRGDDGAQQIKDHDNLNRQEEGELAQSDDWHHGLCGCCASCELCLLSTFVPCLLLGQTSHRIKEPSMESYRHINRDCLLMLGVTYLTGFGWMYVMKKRFEIRKRYGIKGTDARDCCASYWCLSSALVQHEREVLARQAVRSDPITEGYQTQPTMELPSTHNQPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVP9</accession>
    <name>A0AAD8UVP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_611387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367939.1">
        <property type="nucleotide sequence ID" value="XM_060507656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVP9"/>
    <dbReference type="GeneID" id="85391555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="294" mass="32087" checksum="5333C014461F4ECF" modified="2024-05-29" version="1">MDFQPKKQPFSRGSETIVPCQHQSTVSSPCTQSPVQAAFPQPHARSPISHGCSAKGFPSFGTPSAVGYSQSSVYSPSPNTVTMGYSYSSSAPTDRTASYQPVPPQPHSAYAGGSSYEIQATSIRPSSLPHHSHPNSPLTSYSGLSGHSSAASSYGYPYAASSATTSPSTANTPVQPLSPTLIGVGSWDNIRPPIENYEQPTMDRSSREGRRVYVTDFPPNPARSESIEVHRSSSPLKEEDIYTKRRSVRPLASCKDDQKGTSSRPRKDDDKEDRRKRGERRREGVSDRRETRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVW9</accession>
    <name>A0AAD8UVW9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RAD57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_717980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367310.1">
        <property type="nucleotide sequence ID" value="XM_060512008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVW9"/>
    <dbReference type="GeneID" id="85395906"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19491">
        <property type="entry name" value="XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047348">
        <property type="entry name" value="XRCC3-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF66">
        <property type="entry name" value="RE19845P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="7">
        <location>
            <begin position="90"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="461" mass="50126" checksum="9BBB7305E4A2E785" modified="2024-05-29" version="1">MSDLLQLLPDFPVRQFAGLLQTLERHQLSVTDILTQDVVDIGKRTQLPLLDIKRLCAAVVDALHRDFGSVNEQPKASRFLKSSLMDLENQWSTISTLDDSLDRALGGGIPAGYVTEITGESGAGKTQFLLSLLLAVQLPPPYGLGRPAIYITTEAQLSTKRLSQMLSSNPRFADLSPEDKPSLDGILSTSTPDLESQEHILQFQVPVEVERRNTGLIVLDSVASNYRAEFERGTLGNHGSNMGARSNELTRLGALLRELAQTYNLAVVVANQVADRFSSPFAPVATPRAAPAGAAPSFTQESPLASRSRGLRAFSPSAVEPTSSIAEHVRSSMPEPPGLDDFGPPAPPALAFDHQQRWFTGWGDDPLADYGLKTPSLGLVWSTQIACRIALFKKPVYGVHRHIEDEADDRGMPALKNWRRWMKVVFAPHARATGQGLDGAVEFSVTMAGLKAVTKKEADDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWJ9</accession>
    <name>A0AAD8UWJ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Xaa-Pro aminopeptidase</fullName>
            <ecNumber evidence="5">3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_570412</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368434.1">
        <property type="nucleotide sequence ID" value="XM_060504303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWJ9"/>
    <dbReference type="GeneID" id="85388202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF4">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="12">
        <location>
            <begin position="74"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1728379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="55643" checksum="501FEEF49BF27E75" modified="2024-05-29" version="1">MNVSRPVSRALRAVPRLRPASPWRRPLPPSASAAVAGHQLRPYSDVSAADLQFGQPVHETHPHILKAGEITPGITAQEYHDRRARLAERLPDNAVAVLAAADLKYRSGAVFFPYRQDSNFLYLTGWNEGDSVAVIRKTGKDYGDYEFHLFARPKEPVAEQWMGARNGVQAALDIFNADKADDIARIDRCLPEILKGASRVYTDIPKPGSEQNSASNGSSRLVASLMNSDKSWFPSVRIPLYPVINQLRAIKSPAEIANMRRAGQISGRVITDAMRRSWNREKDLHAFLDYRFTADGCEGPAYVPVVAGGRNGLCIHYVVNNNTIPQDEMLLVDAGGEYGTYITDISRTWPASGKFSPAQRDLYEAVLTVQRSSVALCREDANLSLDEIHEHTSAGLLEQLKSLGFEGVTSRDVDVLFPHHVGHYVGLDVHDVPGYGRRTPLRKGHCVTIEPGIYVPDTDRWPEHFRGMGVRIEDSICVDETSPFILTTEAVKEVADIEALRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7S0</accession>
    <name>A0AAD8X7S0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_773938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000306">
        <property type="protein sequence ID" value="KAK1702569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357158.1">
        <property type="nucleotide sequence ID" value="XM_060515410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7S0"/>
    <dbReference type="GeneID" id="85399308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="93"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1702569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="39275" checksum="1E07EE69099D50C0" modified="2024-05-29" version="1">MKGRSWSPIGARRRGLKSFTARMTLRLLAIASVVVMYHLLDLHFRYREDMRVKYLPTQFDSLSDYDEAILSSTRWEVDSDTASSGRGILLDNRRHWKKLGKGREGETFTFNNTVIKVYNEETSPFRNCIQGTDASARRWPTEIPASLIMGGRNDGSKLLDDERYREHFVPVKDYFLAATEPLGTPRWHFVSPFLKSGTLKHLAKKLRKSSNRHSYRELDQMFRPSFESLLSALDSLHMAHDLCHDDVKLENIFVASEHDPRKWKIGDLGNAREPDHPYHYTPLWVADTPQLRDCRANDALRLTKAYFQFLRASSGNPDARPLPDAGLGGADLAALGCLPTPIGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8E2</accession>
    <name>A0AAD8X8E2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_712423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358254.1">
        <property type="nucleotide sequence ID" value="XM_060511613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8E2"/>
    <dbReference type="GeneID" id="85395511"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000609">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF40">
        <property type="entry name" value="REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14497)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="7">
        <location>
            <begin position="192"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1708222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="325" mass="36057" checksum="8F056B481650BF46" modified="2024-05-29" version="1">MTAEGQQIEILLYGLGAIGSFYAFILSRVPRVRLTVIARSNYNAVKENGIAIASENHGEHNVRPYRVVRNAAEAEAKFDYIVCAHKAITQDAVPAEIAPAVDAEKSTIVIIQNGVGNEVPFRKAFPHTTIISCVTWTGAAQPQPGHIKHTKSEDMQIGLYPNNTDQAVEKQRLDDFASLLEEGKTVFQVVPNIQVQRWEKVVWNAAWNSLTTLTLLDTHSWLSSSPDATPMTQRLMREVIDVAKACEVPIEYDLVDKLINKILAMHPIGSSMQNDFKAGRPMEVDIILGYPYRKGKELGIATPTLDTIYVILTGTNLRLLRESGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9B7</accession>
    <name>A0AAD8X9B7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_591303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358867.1">
        <property type="nucleotide sequence ID" value="XM_060506421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9B7"/>
    <dbReference type="GeneID" id="85390320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057026">
        <property type="entry name" value="Znf-C2H2_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24537">
        <property type="entry name" value="zf-C2H2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="468" mass="51793" checksum="24578ACFFBCED6F6" modified="2024-05-29" version="1" fragment="single">LPSISAGFGLHHNQFQLHSSADAFFDVENKLPLVKRFDTKGPGPHLNASSTSSTSDTFSKLSDDVRVPPLSVPTSLSLHLKMSNLLDTQTPSSALSEPAIASRSGISLAASSRRNNSDNALPHNHEAYEMEMKENNPAKRLQIEDPMRAHYDGTRAKRRTSMNPHNTVSLAVTLPSDSLHRHDKSQRRSPTRQLSVIPQQSAFSVPSCCTASHSSDSHLHTRSIASKGLSYGQISPGEPSPGAISSGRNDAMMSLNASLRGSIPRVTYQRTTSNDRPPASPRKPTEASKPDEHKILGGFFLCDCCPKKPKKFTSAAELASHEAEKQYECSFCGNRFKNKNEAERHQKSLHVRDKSWSCSALNDYDQAFHDSKDRPGEADSCGYCGEEFLRNGRGSGDPASHRGTEQDWDKRVRHLQEIHKFRECNMSKKFFRADHFRQHLKHSHAGTSGTWTNALENACILIEDSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAU0</accession>
    <name>A0AAD8XAU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_635183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360442.1">
        <property type="nucleotide sequence ID" value="XM_060509154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAU0"/>
    <dbReference type="GeneID" id="85393053"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="75255" checksum="89630DC3454335BB" modified="2024-05-29" version="1">MSKARAKSEAAILGIDWGSTAIRATICIRKTKELHPIWNRGAVPGHDIRYQTGAFNSTLYVDDRGGIVYTGEVYNGSCTPIPSKWFLCEDRETGNPLLDGLLAKFRGMETKIRRALKAIVRTVFKEVTDFCTDRALHIDEVGLSHPAHWTAQELSSYENLIASAMMESNTFANAHGRIKLHVESLASAHFLFSSPRHMKQILTKVDEPCHLVFLDFGGHTMNGCIFSAVRRSGDELNYFQVGEPFTAHGGTQLWEKRVDDFATNYVEKSLKSTLLPSQRADLLEMFHLKIKRLQTGLFASMVLHAEDPDNHSSISVHLRATDARQCFLDGLETPLRLARKKIDAAVALGSNVKIVLSGGSGKNVLVQANLQQACAQLKIDEPFLFYEAVGEKDSFNISKGAALAAVDNITVQEFINRGAAFGFQIGRPLKGANGSFISWESAATLALDSDGTHYFRKRYSGTTRLKIVCDPQLQASAKWDHIPAACCYDILELAPPTKGHWEYCLRLHDFGDGKLGLIIRKNKLSWKGKSVLERMTYGPFPLEYDTSSRCCLINLDRVKTESTDFESGIFLTEDGKLVPCDPEAVNDQIQDLQKENNDRLRESSGITTSMPQKLKGQQEKQGQQEKQQECKASGKRPRSTLVAQMSDDGKPRKESDRDDDRGQEPAYKKRLMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAX3</accession>
    <name>A0AAD8XAX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_633613</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360999.1">
        <property type="nucleotide sequence ID" value="XM_060509046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAX3"/>
    <dbReference type="GeneID" id="85392945"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001530">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000057">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="706"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="749"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="819"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="931"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="967"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="52"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="377"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="709"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1031"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1717512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1280" mass="139734" checksum="C9A213F530F0E7C4" modified="2024-05-29" version="1">MGAEKKEHTPVEDTVAAIASPNEAVKEEGGAFKAYLRIFSFGGPFEKLLQTIAIICALGAGAGVALQNLIFGSFVTTIQDFTTGQSTPQHFRNEVSKLALYFVYLGIARFILAYGYISLTTFSAYRITRNIRHAYLHAALRQEVAFYDIGSGGSIATQAISNGRLIQVGIAEKLALTFQGLAVFVTAFIIAFVTQWKLTLIVCCIAPLILVVMGVVSTIEAGLETKILDIYAQAGSFSEGILSSARTVHAFEIRSRLVQKFDRFLEDAHRIGNKKSALFGVLFSFEYFVIYAGFALAFWQGIHMLNRGEITESGDIFTVLLSVVIGATSLTMLAPYIIEFTRAASAAAQLFKLIDRVSEIDPFDKSGHQPTETVGVVDLENVSFEYPTRPGVTVLDNYSLHVPAGKVTALVGSSGSGKSTIIGLIERWYNPKSGTIKLDGQPIDELNLNWLRKNVRLVQQEPVLFQGTVFDNIANGLVGTPWESSPREEQLRRVQDAAKIAFAHDFVSQLPEGYDTMIGERGGLLSGGQKQRVAIARSIISEPKVLLLDEATSALDPHAEGVVQQALDKAAEGRTTIVIAHKLATIRKADNIVVMNKGAIVEQGTHEGLLAQGGAYTRLVRAQNLNVAEEGSITETEEDDDEAVTAAAAAAGKEDIELTKTMSRYRTTDQTRMEAQKERDNFDHYKPIGLISVVIRMVRETPELKWAYLATLLAVIVAAGAFPGQSLVIANLVDVFTMTGSEMITKGNFYSLMFFVLALGVLCCYFVMGWATNVIAQGLNHKLRRQSLNDFLRQDLQFFDRVENNTGALASRLESNPQAILELMGFNIGLILISSLNVIACGILAIATTWKLGLVVVLAGMPPLVSSGYIKVRLDSRLDTKTSKRYSASAAIASESVTAIRTVSSLAIEESVLKRYTDELDNAVRASTGPLFVMTVAFGLTQAIEYFFMALGFWYGCRLLSFNEITMYQFFVAFMGTFFSGQAASQLFQYSSSMTKGINAANYLFWLHDLQPSIQETPQNRDAAPKAGASVDFQQLRFSYPLRPEAHVLRAVDLEIKKGQFVALVGASGCGKSTMIAMLERFYDPTTGSIVIDGDAALSDLNPRLYRHIVALVQQEPTLFQGSIRENISLGIDAESLDEIVPDTKIEAACRAANAWDFVSSLPEGLATPCGSSGMQLSGGQRQRIAIARALIRQPKILLLDEATSALDTESEKIVQRALEEAARDGERITIAVAHRLSTVKDADVICVFYGGRIVERGTHAQLVARGGMYKQMCEAQNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBN5</accession>
    <name>A0AAD8XBN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_584585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361794.1">
        <property type="nucleotide sequence ID" value="XM_060505770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBN5"/>
    <dbReference type="GeneID" id="85389669"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000078">
        <property type="entry name" value="MFS maltose transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF33">
        <property type="entry name" value="SUGAR PERMEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="38"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="516" mass="55687" checksum="9CC99AF5A610C946" modified="2024-05-29" version="1">MGPGIASVGSGTGEDIINAERQLSVLSNAKRHWRALLIASVAFSAGIVFAYDTVTNGASISMPSFLLYFGEIGPTGPYLPSIWTSLWTAMSSLTQALGAILVGFVSDRYGRKWPSCAAAVLTLVGAAVQYVAVPRATLMGGKMISGLGIGAVMATATTYIGEVSPLKLRAPLQTCFVIFVLLTQGLALGVIRIFVPDIREQAFRTVIAIQWAVGGLAVITWAVAPESPIWLIKKGKIEAARKVMRKIYGPNNPDERLEYEIQAIRAEQELEKNNNATYAACLQGHNRKRSLTVAFLYSTANIGGAPFLAQNIYFLITAGLEAVHSFDIGIGGFAFAVLIILASGAYLQRISRRNVVLLGLVINLLFMVIIGALYWVTNKGGLWAIAVLMNLLISLQAAFLQGAGWPIAAEIPSYALRAKTLSIGICAQTFTTWLFNFITPYMYNVDSGNLGARTGFIYAGTSVFLLVGAWFLVPDTTGMTTEEIDKAYESELTPRRFQKHAVTAYMGPDGKSLRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCS8</accession>
    <name>A0AAD8XCS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_546574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1722984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363039.1">
        <property type="nucleotide sequence ID" value="XM_060503450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCS8"/>
    <dbReference type="GeneID" id="85387349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="140"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="39418" checksum="D06901AD34E9FC00" modified="2024-05-29" version="1" fragment="single">MNHERYQERLDLVKSVIHNYGLEPVDITPIDYDETAPFAYNNYIYKITLSAPLTPSSVPHDRRRPYTQPPPGQGTSTVVMRIANPKAEGVVQDNRVENEVAAIHLAREGLGSYRPEIAELVPALYDWRPYRPSENAETEAVVGIGAGGSSSSYGWSLMEFKEGVPLDTVFRDMDDGEKSDVLGQIADLVTGIQRVSLPESVRSHGGLSIDEEGRIVGGAMTTVKGGPWKRYSDFWKARLAIRLGDADASPALEGWRPNGVRERVDRFLESGLERYLDGSGVDVGKLALIHGDLTTNNTLYDPTTKKLTSILDFDFAFVSHPCHEFFTSLGDVGGNTGGGTGRDPDLSGGLLGKAMLTGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD04</accession>
    <name>A0AAD8XD04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_582527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362722.1">
        <property type="nucleotide sequence ID" value="XM_060505562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD04"/>
    <dbReference type="GeneID" id="85389461"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="375" mass="41485" checksum="DD411D3FE207D55F" modified="2024-05-29" version="1">MSAPESYQLESLASDADGVKPTSPTASIDPANVRWMNQGDRRWEVCKIVTRLVGTLLCAIILIIMMAWYGYPPWDSYSVWPWLCLPGALPSFMWDLGEFLTICARHGRGITPKAHIGLELIISILGYIGGGWLAFQLGVQEDDQIGNNPLNLALVVCIFMLLSATIHMALFIRACIERSREIRRRRPRVMYIPETGQTVYVVAKPFPKLPTWKSQSTRGQSFPRSPQSPLSNSLRHHFAQLQEEMPPPLPDRPGDQSPSSASSIKRKPLPGAGIPSRGIPAGGDSRDRHLRPNMRPPPADYEPSAEELERMRRGDAQPQLILPGDVDFKFATSVTGMTPADASAREGKYRVNMTQMPVVMGESSRGGSAGRTRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDN9</accession>
    <name>A0AAD8XDN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHRD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_588765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359995.1">
        <property type="nucleotide sequence ID" value="XM_060506170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDN9"/>
    <dbReference type="GeneID" id="85390069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010895">
        <property type="entry name" value="CHRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07452">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00754">
        <property type="entry name" value="CHRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042233923" description="CHRD domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="CHRD" evidence="2">
        <location>
            <begin position="48"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="207" mass="21896" checksum="414844295E4F8E30" modified="2024-05-29" version="1">MKFAIIPLALATAASAAPIVEEIKHAVGWTKKGGKGSWGSSGPFHFTSTYDVIATPDQVVDNNNTFTGGLAGAIGYFNYGINSKENVICYNITLVNFQGEYQSPARTATHIHQAEKGKAGPPRIAFPNPVAVEGYQNVRRSVGCLTGPFVTGVNASGVDTGSGFKVSQIEENPEGFFTDVHSSLAVPGAVRGQLGDDYKKDCPEDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDV6</accession>
    <name>A0AAD8XDV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_415858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362741.1">
        <property type="nucleotide sequence ID" value="XM_060502945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDV6"/>
    <dbReference type="GeneID" id="85386844"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="282" mass="31695" checksum="211047299749EE23" modified="2024-05-29" version="1">MAIVAALRKFETLSEIVITDGFSQPTAASLASSPSNKRPLHDIASEESISRLMAHPTISMSDMNEEDLCATAKMAGLVLDLLRSLDVHVIQPEYLHVNFIPQPTYESFLHSFQLTDGIPPFNKLMQNVRALAITIPEESNIMDEQGRWRGEGFEEVEDSLRRFFDYLTDAPNLEDLFLAGSGVELPGDDDASQTERFLPTWHVSNIIQPKAWPDLRKFSIEDIWIEPETLRGYIGNRASRLSLSYVLGRRIDGSTLKMLRKMARKGRLNVSSLGADGFEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDY0</accession>
    <name>A0AAD8XDY0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_623909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364269.1">
        <property type="nucleotide sequence ID" value="XM_060508417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDY0"/>
    <dbReference type="GeneID" id="85392316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="496" mass="55883" checksum="7BCFF87C61C86D3E" modified="2024-05-29" version="1">MAVVLIFAVAVFLGLLVKEFYSWYRLSHVPGPFWHGITGFSMARAALNGSVHEYYMEMHEKYGPLVRIGPNTVMFSDGDTLRKIAGTRSKYIKGEWYAVGRTTPGEDHLFSMRDEEKRKYLKSKMGPGYSGLENGGFEAGIDKNIAAFVDLIDRKYISTAKDFRPMDMASKSTYFALDVISELSFGTPYGFLKEDRDLYQYVATKDAFFPVMITMGNVPWLATLMHSWPLNLGLPKSGDSAGFGALMGFAKTFVDGRLAPDTKPGRDMIQSFINAGLTREELTQEVYVETIAGSDTTATAIRMILLSLLSNPQAFTALRAEIDTLVSNKMISSPVKDSEARFMPYLQAVIREGLRLYPPSTGIVSKQVPSEGDMIHGYRLRPGTQLGENVCSIGRSKEIFGPDAHLFRPERWIDAAMSEDEGRYKAMISNTDMVFGYGKFYCMGRNIALMELNKVFVELLRRYDFAIAKPEKPMRLWSAGFWITHDFWLRITLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEN5</accession>
    <name>A0AAD8XEN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ERCC4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_625843</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EME1/MMS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363596.1">
        <property type="nucleotide sequence ID" value="XM_060508516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEN5"/>
    <dbReference type="GeneID" id="85392415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20085">
        <property type="entry name" value="XPF_nuclease_Mms4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.670:FF:000004">
        <property type="entry name" value="Crossover junction endonuclease EME1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047521">
        <property type="entry name" value="XPF_nuclease_EME1_ascomycetes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="15">
        <location>
            <begin position="463"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="112"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="593"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="404"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1723541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="783" mass="86462" checksum="05D4E0B9188DE4FA" modified="2024-05-29" version="1">MTAEVIDLLSSSPSWPSSKNARPPLPRPAPLVSAAVVTPLAYGDEDVFDLTAESPETIPKPLPLPSVLPKATSPSLTNSATKRAREETVPVNTPIYFNSDDFDTIVDLESSLPIGNGLNNEPRDRKRPRLSSPRRSRRSSFDRSHSATDHSTRLPQKQSDGLRRVRSVVEPIEFSSSPGVFSPPTTSAPADDPFAALPPSAQPAPICENPLPKATTTGPGHINYELSSDDPFASSPPVARKAIPQPPTILLDNDDDDPFASSPRRAPTETVKPPDTRTLAGTTAKGKEKVISPPRRKAHWDPISSSAPEPKTRRDPFESSPPPPRKTMTKAASAVINLSDSEPEPAARGLDADSDGEFPDLDNFNVSKLKARLDTKKPSSRTTLRVPSKATSKSSTSRPTTTKSVEEKTREKEAKAAEREREKERKKQEKEAIKEQKAKEKERAAALAEVNKIRTDKKVSTPEMIADLPASLPATMTLQIQTLLKDLDVQHSTWESPVDNVVKWRRKVASRFNDELGHWEPIPMRIQPDKFALVIVTASEFVTYALGPEGNNLEAHVSKMKQHFPKEQIMYLIEGLNPWMRKNRNVRNRQFASAVRGEDAATGDGQTSTSAAAQPRRRKNQQPQEYIDEDSVEDALLQLQVMYDVLIHHTAAAVETAQWVAVFTQHISTVPYRKQREATNAAGAGFCMETGQVRTGEDVKDTYVRMLQEIARVTQPVAYGIVSEFETVGELVKAFEERGPLCLENCRKSTNKDGGFSDRAVGKAVSKRIYKMFTETDEWSTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEQ1</accession>
    <name>A0AAD8XEQ1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_633801</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360940.1">
        <property type="nucleotide sequence ID" value="XM_060509053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEQ1"/>
    <dbReference type="GeneID" id="85392952"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209184" description="alpha-1,2-Mannosidase" evidence="11">
        <location>
            <begin position="27"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="459"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="739"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="739"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="779"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="860"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="583"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="700"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="932"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1018"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="657"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1717453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1027" mass="114787" checksum="B0A1E29914ECCB1D" modified="2024-05-29" version="1">MMPRRRSRYVILVAVVMVFMLYQVFKNPEWDSTGQSSSIKPSEPERGQNVHKDSSKPPPANDPASNKHLNNQPPPDNEHPHDQEEDEPEQNPQKQTAKPTVKIPQLKTEKAKAPTNTLSGPTLSIHAYNDEVEATKSPEVTKAPTKPLELEEDLHAKKPPGRPNFDIAESLSTSTSQIHWHKVSEHFPVPTDEIIPLPTGKPKDIPKIQYDFKPESEAAKDKREKRLALIKAEMLRSWGGYRKYAWMHDELSPVSGRNRDPFCGWAATLVDGLDTLWIMGMKEEFAEAVKAVKEIDFTYSPTRRDIPVFETTIRYLGGLLAAYDVSGGKEGGYTVLLDKAVELAEILMGIFDTPNRMPILYYNWMPEYASQPHRATTVGVAELGSLSMEFTRLAQLTGKDKYYDAIARITDAFEDLQNRGTTIDGIFPEQLDASGCNRTAEAIIYQEAQAAAASASAAAARLSEPQGHEPAAAEAKRDETDPILPQETAVAKGNGSEPESNPLARRAVGVDKNGESVVENANIDNKQAFPAPKVNEQPLYPGNSGRRPSTPTTPDKSSWECIKQGLAPGGWGYQQYSMGGSQDSTYEYLPKEYLVLGGLEQKYKTMHIKTVEAVKKWLLYRPMVPKERDILFSAKVSTSGDPENDLRTEYEVTHLTCFIGGMFGLGGKIFDRPDDIEIAKKLTDGCVWAYETMPSGIMPEGASVVPCASTKSCPWNETLWWEHLDPSADWREAQVKAWEDRQREKKQQKQQDALRKQTTERGNKAVEKSTEETIQSESPVEKKDPLDDIHVPKDEPKKLGLAEKTEYPAPEPGLNKSPSNVDEHLLKKRDPAPPVSQDPRKGTAQEAASNTLKDKLDLNNPGSATDDITGSVPNDAPVSGGIVGKIAFEEEGEVPDPKPLSHEEWIKDKLELEKIPPGFVNINARRYILRPEAIESVWYMYRITGDPVWQEKGWKMWEAIIKATRTEHGNSAIDDVLSEDPQPVDEMESFWIAETLKYFYLLFSTPDVVSLDDWVLNTEAHPFKRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEW0</accession>
    <name>A0AAD8XEW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_555222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362228.1">
        <property type="nucleotide sequence ID" value="XM_060503514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEW0"/>
    <dbReference type="GeneID" id="85387413"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55537" checksum="8881B31372ADBC1E" modified="2024-05-29" version="1" fragment="single">IEISDAQRRYLEEEGAFLELPKSTTDSLLSIYNVLLDDLIPVVDGAAIFRDYSNGQASVFLLRAVSLIACKFRQAAPFLRIREDGAIMDQRHFASELLKGLDASIKADLEPDRITKIQILALMHLHNDGLGGLDRSSGYLSQAISEAWAISLHVKIPVNSDQERCDFLWWTLRNFDRLNKPVMGAAPFMIDDTDIGVERIAPRKNHYRSQLIAISLSLGDLMKTATKIYKASSTAMDDDSDAFPTFSELTTNLCLDGFQKSHRLYLQIWYHVAAMLSCRYSGPKSVQYQRRLSSADNVLRIVCLEGPANLPPLPLIPYAMSMSTTVIYRALRDGERAPDEAHKDLGACYDNLVILSQLWTSAKGVARLVRRLQHFTRPGAPPIRTTEGAPCTCDNTHQHENITRNPISNLNNLQRPNQGTTGNSVLPVSSLMQPSEVFLPQNYTDNDGQSGNQAGSWFVDGLSYSHFDRAFYDFFDYGMPSLFRDLATWDFLQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEW1</accession>
    <name>A0AAD8XEW1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365274.1">
        <property type="nucleotide sequence ID" value="XM_060514133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEW1"/>
    <dbReference type="GeneID" id="85398031"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="369" mass="42070" checksum="51C3D3FB10BE6A9B" modified="2024-05-29" version="1">MPFTKFAELPAELRLKIWDEATAGPSIHIFDVCFPSWRGTDRSRRAFQSADGKISEQNHARWTKYRECVFLDALETGPAELARQTRIARHMHDPSVYKQRQTMRLVCSEASAAEERRSKGSSMNSVYLPGRNQRIHYDNEEDVLLLRFGDGGALTDLSHGVLFGEYEASGVNNLTEVLEGPWSAEIAERLRDARLIALDIAETWTPATVGAVMFEEVAYLACCIQRRLRVLYLVDHCHGRCTRCKKQDITRPQLQTRGELYDQLHSRDKDTARSRVADVIHGVGKTYREVFDLEGMGWSDEHPIYVFARVMDEMIRGQQADAKTQDFEGIRVLLVEDDELEGVDNTTMMDCYPDGRPEVANEEMSMSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF27</accession>
    <name>A0AAD8XF27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362453.1">
        <property type="nucleotide sequence ID" value="XM_060510680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF27"/>
    <dbReference type="GeneID" id="85394579"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="26169" checksum="1828B623A9A4F74F" modified="2024-05-29" version="1">MPAIPIFKDTPINASKASGATPQTEEPQAKDHSNNVAESSQSQVGAPAPSSTRQQPYPPAQPGAAPSFPVQTASAQAYPAPRPTPTQKTNDVSPPPPQPGAAPVPVPGTSTLPPPPKAGQTYQPPAPTPATTATVSYPPQMGIPPPTMSHAALRGSSTSTTNGPQMTGPRPVPLGGDPPLSLEHPPGYQQDVSASEFSSHQRAAHQAAVASSAEKGYQSQPEEGVWDTAKKWAQAAGGSLAAAEQEVWRRINKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFJ3</accession>
    <name>A0AAD8XFJ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Beta-glucuronidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_792014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365512.1">
        <property type="nucleotide sequence ID" value="XM_060515746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFJ3"/>
    <dbReference type="GeneID" id="85399644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF3">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042117001" description="Beta-glucuronidase C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="2">
        <location>
            <begin position="373"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="50413" checksum="184306EA24EF63BE" modified="2024-05-29" version="1">MFFSISELACLLAAAHGAAAVTYSVPAKVNTGGLSYAPLEAAPLGLSFEFFAFPAYFKNVTATNQCLANLKDLTGTWPPIRIGGTTQDRASYDAATSAYVVYSVANAADAPASLTFGPNFMKLAATYAGDVTLGLNRGKNNIDNTIAAAKVAVQEMKNLYAIEVGNEPEYWSGVQPIAAGGWSPALDAASQNHWDITVGNAIGRKTIIQAGNSNSLPPTWGAEELIASGNATVREYVKTYAHHNYPGGSVTGLMSHSSISSNVHLFDKDIASALAVNKPYIFGETNSVAGGGAANVSPTFGAALWVMDYAVRLAMSKVSRIYFHHGTIGNNPYAFFGRYSNGNPYVGAYAATAFMAGGKHLAALDDGKSALAAYVTYDAAGAPLRALLYNSNYYSGTGTRGSESFVLSGLTTTAGRVRSKRVTAASAEARQDRGGNASFGQQFFNNGTCTIGGTETFETTTVSGGQATFSVKASEALLVYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGA6</accession>
    <name>A0AAD8XGA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_751961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365216.1">
        <property type="nucleotide sequence ID" value="XM_060514127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGA6"/>
    <dbReference type="GeneID" id="85398025"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042174765" evidence="1">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="67" mass="7235" checksum="451394EA7718441D" modified="2024-05-29" version="1">MKFSAVILFVASVAAVALDTDVPPALSQPGRRGVDCGACDRLNFCPGKPNNNVECELDGCCKNYYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGB0</accession>
    <name>A0AAD8XGB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_625489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363788.1">
        <property type="nucleotide sequence ID" value="XM_060508494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGB0"/>
    <dbReference type="GeneID" id="85392393"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="153" mass="16189" checksum="E3D3D0C634B5E059" modified="2024-05-29" version="1">MMHVRISVGGILCTAYSFRHLVFIATPCVLLATRTTLTVDQCVLGILTLTVGSLGHRGCVGSFRVTQVGMSCRLGGGGRRDSKTLPGACGVSLVSLIPKDVWSDGLYAGRDLQCSKNQPNGTCHALLLLGTPVLMRVASVISSLDPRACHCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGP4</accession>
    <name>A0AAD8XGP4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_579299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364223.1">
        <property type="nucleotide sequence ID" value="XM_060505221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGP4"/>
    <dbReference type="GeneID" id="85389120"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="60980" checksum="1E66C0CB608774FF" modified="2024-05-29" version="1">MSQPTPWASEPSTSVMDAPANPQSKSPFNKVPLEVLIRISDQLSTPDLGNLRLTCRSIEQSMFNMFMKEFFTQRQFMLTEFSLQTLIDISKSRLSDCLDHVIIGLNTFTRHYFSPGEEANETRYREAQSDHHTLVNSGQDVAMLTEAFRNLKNLKTVGIRDYHSTGRGFRDGFEVSWASYGATTLRQDTGVDLLRIPIDEMVTYTNKVFITLFTALGNAAARPSAFELHRHQQGVPSDDAYNLFTKYLKPKVVPVLEGIETFMSVVNVATGPFRVTSLTGSMGTQQRRRYDYLLRLFLGYMPNLKHLRLNFAHPGHNTDAVDEFIDWLGTPASSAISEPYDNQLPTPPAPVAFSHLEEVNLGFVEVEPKRLLKVVQKLAPTLSNLELWKVTLLARTGAVQGDYNARGDISIINMWARFLQSLRDVPNLDLKHIMVGCPAQRMSMTSTRVWVQATDGVPDKTVARREYTGIDWRHFVGDLAKQIMVDIPPERERNPDSDEEDDEDTNGDMDDDIDDGIDGMDDDLDNDMLEDDIMEAIQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHA6</accession>
    <name>A0AAD8XHA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_575049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366326.1">
        <property type="nucleotide sequence ID" value="XM_060504771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHA6"/>
    <dbReference type="GeneID" id="85388670"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF6">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE APDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="20"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="340" mass="35928" checksum="221E06A4266F73A6" modified="2024-05-29" version="1">MTAPESLPTTHKALKVSGPGHVYVSEDASVPSPDRSELLVRVACISINQVDCKSADLSPTPGATSGTDFSGVVVALGSDVDAEAWHVGDRIMAGIFGNNPLRRDNGAFAEYAVVPARLAWRIPASMDLATAASLPAALATVGLSLFQYMKMTMPDNTAGALQLSSNTDSAGASNVANPATYLGAAATFDYRSPSCGADILSYTQGALTLALDCISDSDSMTTCYKALGPAGGRYVALDPFPLRGHTRRSVEPDWVCCYTQFGHDVAWAPPFDLDARVDDRNCAEAWYVLAQRLLDEGLVVPQPLEVRRGGLAGVGEGMQEVRRGLIKGRKLVYSVAEIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHY9</accession>
    <name>A0AAD8XHY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_620019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the free Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365438.1">
        <property type="nucleotide sequence ID" value="XM_060508173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHY9"/>
    <dbReference type="GeneID" id="85392072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033745">
        <property type="term" value="F:L-methionine-(R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.40:FF:000048">
        <property type="entry name" value="Free methionine-R-sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF15">
        <property type="entry name" value="FREE METHIONINE-R-SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="65"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="176" mass="18885" checksum="7B22C2961F868B56" modified="2024-05-29" version="1">MVHADASNFANGVTKEEAYEQVLMQAEGLLDGQRNWVANLANTASLLWHAYHSLPAPSNAVNWAGFYVLDPSSTKQSLILGPFMGKVACQQIPFGRGVCGAAAATKQTQLVADVDAFPGHIACDGDSKSEVVVPIVVKDKLVAIIDVDCAERDGFDEVDRVWLERLALLLAGGCDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI20</accession>
    <name>A0AAD8XI20_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_751722</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365528.1">
        <property type="nucleotide sequence ID" value="XM_060514092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI20"/>
    <dbReference type="GeneID" id="85397990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045048">
        <property type="entry name" value="FBXO31/39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706">
        <property type="entry name" value="F-BOX FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10706:SF130">
        <property type="entry name" value="F-BOX ONLY PROTEIN 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12014">
        <property type="entry name" value="Cyclin_D1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="94"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="62979" checksum="0C77C9862531FD9F" modified="2024-05-29" version="1">MATSPPSPSTSAADSDAPTHDTMSTASGSNYGGIDPEVEENLYILPYVSEEGLRSDATDHRKTIGSSREEYYPLPSDFNIAASGTLPSLASDNSCRLLALPSELIDAILAYLPPCDLAIVAETCRTLHAHAASDIHWYQRVQANVPGEKVTTPYPCRTYRELYAAHDPRWFLPKYKIWFCDRDLMGKMMIIRYDQRRGCIEGYQLLAVSNRTTYQHWPADHSVIIHAFEPQVKLHLDKPVLQFHARRPGEDEGLLGSLGQRFLPEVPMSIHDPMDAMFCNFMMARPLEAVTATSRMDGVFPYGNVWPSPAIPARHRVSGVVSGLDGDDLAPGDQPTRRAEASDQAFRIRQWMEMAGSPTPGLFLGPGPVGIIQAIQANMGMGTPGVTGVRIGEEVITYSTLDPVVYTPTELKPWRGVWVGDYSGHGCEFLLINQPDDEEVSDEELGLVRGSDEAESEWTKRRTDARVYRGRLEAIKLTGDPNVPRGEYTFVADDLGEAGFVGIAQEPPFQGTRVIRSKGHVAGTGFLDDKYIESQLMLVSHDRLAQYWVGFGHISFFERVNIDEFVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI29</accession>
    <name>A0AAD8XI29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MYB DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_571541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368107.1">
        <property type="nucleotide sequence ID" value="XM_060504419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI29"/>
    <dbReference type="GeneID" id="85388318"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="182"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="26223" checksum="2EE730965C067CBF" modified="2024-05-29" version="1">MDPGHHMSHARHLGPPHYGAPGPVVAPLYSSMATPTQSHTPHGVPKRPRPDELDLSVPGIDLEQTDLETMQQTPLGTAYAQATQQVQAPTHHHHRLPDTGPPSKMMRRDGDGGDRGGAPSVVGQAGMPTPAPRPRGPKLKFTPEDDQLLIDLKENKSLTWKQIADFFPGRSSGTLQVRYCTKLKAKTTQWTDETDQKLRTALQDYENEKWRIVANKVGTGFTPAACRERAQELMGGPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI66</accession>
    <name>A0AAD8XI66_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_618784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365708.1">
        <property type="nucleotide sequence ID" value="XM_060508089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI66"/>
    <dbReference type="GeneID" id="85391988"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04330">
        <property type="entry name" value="RNAP_III_Rpc25_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000221">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="9">
        <location>
            <begin position="83"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="197" mass="22405" checksum="CA1C28D000D9DE96" modified="2024-05-29" version="1">MFILTKIADLVEIAPEDFRKKSKAAIEDNINAKYANKVIQKIGLCICLYDLLWTSEGLIGHGTGLVNVNVEFRLIVFRPFKGEVMIGRIRSSTPAGINLRTDFFDDIFIPFDELPEGAEFNHSEQLWIWNIEDDRLFYDNHEMVRFQVIDEEWHDQTPAGPSQGEEAAPPKPPYKVKGTMAMEGLGVCLWWDGQGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI72</accession>
    <name>A0AAD8XI72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Prenyltransferase and squalene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_570954</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368272.1">
        <property type="nucleotide sequence ID" value="XM_060504360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI72"/>
    <dbReference type="GeneID" id="85388259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="9"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="47499" checksum="09212C21AD7AA725" modified="2024-05-29" version="1">MAANAVMPLEKARHIKYWQRCHKTFLPHQYTSSDSTRIALSFFILAALDILSPSEPTKDAPHLLTPADRAAARKFVLGLYHPGGGFCGSPNHALPSDLYADWDFEKGAPGTRNASSANLASTYFALLILAIVADGPEEAKGAFAGVDRVATLRWLRRLQRTDGSFGELVLDDGAIAGGKDMRLCFLAATIRWALRGDVKEGDEDWVEDIDVDGLIRHIRQGQTYDGGLAESSHANESHAGYAWCAVSALVLLDRPPDQSGTPHDSQVLQQGVSDASLLVKFLVYRQFEYLEKEDDSDDPDHANFTLPASLNELTLDQNLRFVGFNGRCNKVADTCYCWWVGGTLQMLGHTDLIDAEPSRRFITRKTQHLIGGFSKYPGGPPDIYHGFLGLAALAIMGDADLKPFDASICATDATVRNIIFARNGLIEATKETQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIF8</accession>
    <name>A0AAD8XIF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_608441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368602.1">
        <property type="nucleotide sequence ID" value="XM_060507481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIF8"/>
    <dbReference type="GeneID" id="85391380"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="968"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="9">
        <location>
            <begin position="33"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="573"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="606"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1055" mass="120005" checksum="70EB39BF066255E9" modified="2024-05-29" version="1">MELQSWDAFQETLPPTKHMKEIHRKKLALRHPGTCSWIFDSKVYRQWENESNKTLFCIGPPGVGKSVLAAAVIDEFKNSDSLVLFLFCENHSQQMDFLAGCLIQQLLERIDYGTDVELLSKLSGPRKDDNVGNNNGQTALESLLCHRSTKSDTERARISLVLDGLDRLDNGVSRSLLSFFSRLRAKIDIKIFATSTFDVSLATEDNSVTALPMPVSDTADLKEYVTSHVKPPASYSTPEHIEFYETILKATEGIFHVASRIVEELSPMHTKFEFQQFLRHWTQERRHLDHVFGELIEARSDHIQSSLASRVIDWLTFSHRALTMLELQHALVADVSEYLRVPPTPEKITSALHGIVTIKGEQGEQSIFFFHSAVKDYFWHERSDRAPKIHDNIVSYCLRQLSRISSDDGFCKSDEDFEERLSHNPFFLYAACHWGFHTQACSEPVAAAMRFLDNRVNVVMSSQAILIDQSSSKAPGYTQHVPQNVTGLHLAAYFGIRTAAEELLSEGTAPLSSVDTQGRTPLWWAAHYRQDKVVRLFCRSDTATLSLLVVAKEGDLIKILLDGKYNVNIADASLDTPLHHAVRRSYENIVKNLLSAAANVNVQNMGGETPLAIALNNRNSNIINLLIGKGGYTDFVNTAKFRKAHGWQDDQTLEIFRDDKTTVLRLKPEDRRSFEDWGPTERFSLQVSPFTVATDCDAYHFHRQQQILGDVPFSPRLRRLTDNLQIDELNLEIISQEDNKSHITYYIEAFMWNSPNNDEALPCKQLVLCWDVFRDEQTHQWHTKAHFTTMPHIWLPDNGAVFLRHFLVHVKHTWLAYCDANLVDLHLRKRIIESKGSDPALLDHLLENGQRWLSHRHNLSKVASSIRNFARKYCLQHNETGDLEELTEAIDQLAAAVGKKLGELDENSRDLIQLECNLVSIKEARQSVHSSTSMKRLSWITFIFLPLTFIGTLFGMNIDILDGKPKPAWWTYIPFAIVTSLLTSLVWLIFKFTELETTIETKARAWLSQIKDAATRREQQDVKSKSQFSSRSANNSSHVELSILENGQGVTNGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ25</accession>
    <name>A0AAD8XJ25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_614074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367133.1">
        <property type="nucleotide sequence ID" value="XM_060507803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ25"/>
    <dbReference type="GeneID" id="85391702"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="21662" checksum="C8FD249C374CE834" modified="2024-05-29" version="1">MTQAYIIGDSSPFLKRVLIPFWVIRIAIMVLEIVLYAGTIAVAASNKEALNDYGDDNRTASWVIGVLCVIMVIILICLILDIVCIVKRSRRTLSPKFFLVSNVIQTLVWVILFILTIIGAGGAFTFIIAIVVLASFVGLLIYASVIYHKFRKGTLPRGNYAPANPSTGYTGGYASNEPNKTYDPNAARYEMDQRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJT0</accession>
    <name>A0AAD8XJT0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF159 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_572352</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367540.1">
        <property type="nucleotide sequence ID" value="XM_060504496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJT0"/>
    <dbReference type="GeneID" id="85388395"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="21"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="301"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45834" checksum="6ADB8FFA36095B6B" modified="2024-05-29" version="1">MCGRYALALRPSQIRRMLEDDDMAVDDAPEDEGQGSPRQTYNFAPGYHGVVYRADVPDRGAGHGRHQGSSQQDSAASSQSHSNDSGDSSVKYKMQSMQWGLIPFWTKRDPGYATLSKTINCRDDSLSTPGGMWSTMKAGKRCIVVAQGFYEWLKNGKEKTPHFVKRKDGQLMCFAGLWDCAQYEGEHPNPQPFRIDAQEKRYTYTIITTDSNKQLKFLHDRMPVILDPGSKELKTWLDPKRHEWSKELQDLLKPFDGELECYAVSKEVGKVGNNSPSFIIPVASKENKSNIANFFANASAKQKSKEATKLEPTIETKEEPKESQVGQDQPVPEVIAKAADEEGSQEVVGVKREAPDAVEDAQEEPPRKMLRVSPVKGRQSRINPTSNGSRSPVKSKQGGTQKITKFFANSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKZ6</accession>
    <name>A0AAD8XKZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369387.1">
        <property type="nucleotide sequence ID" value="XM_060510133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKZ6"/>
    <dbReference type="GeneID" id="85394032"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042140089" evidence="1">
        <location>
            <begin position="22"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="17663" checksum="29E8742C852DF80C" modified="2024-05-29" version="1">MFSTLIQTFVLLLLTATAALAAPAGRHNWPRFTVPQQHFEVLSMRMQEPVNPAAMVEATCIDRNAHIVFHDQNAAELAICGGISGSVDACHGNPSTTVGQAGSARFALKTTVEGAQITISKTKWEQCVRAARDKCPTGSLRAVCAGGATVGDVEFTLKNSFSMDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL57</accession>
    <name>A0AAD8XL57_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_606143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369369.1">
        <property type="nucleotide sequence ID" value="XM_060507363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL57"/>
    <dbReference type="GeneID" id="85391262"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF26">
        <property type="entry name" value="FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042022747" evidence="1">
        <location>
            <begin position="21"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="481" mass="50832" checksum="E0ED6BEA06389708" modified="2024-05-29" version="1">MKFNQLASPAWALLLSQAAAKPCAEAKIDVDVAIIGGGSAGIHAAIQLKDAGAKIAVIEKKSQIGGHAETYINPQTKIPANVGVVLLENREIVSNYFSRLNVSTIKANPLTSATAGASKSYDFSLGFPIPAQNASASAAQQQALQAAAQAYSTNVLAKYPWIDQGFLVPDPVPEELTLPFAELAQKYNFTALLAVIAQFNWWTGDISTIPALYGIKGLGPGLLQSLFGEFILSGNGDTRALYDAAAVELGDSVLLNSNVVKVERDVKIDKATTSGVTVLVQQPGQPKKLIRARKLLIAIPPILENVAKYDLSSDEHALFSKFSALGYWAGVATIPGLNTSLTNVGVQTPFNQPVIPGTNGFNTAGSPNDFLVAVGFQDTNYTEADAKAVLVKNLATLAAVGAVPKDAAQTVTFPYVSDHKPYNVRVSTEEIKGGFYGKLLALEGARNTYWAGATFSGHNSALVWSFNEGTVLPGLKKDLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLL6</accession>
    <name>A0AAD8XLL6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_604438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369676.1">
        <property type="nucleotide sequence ID" value="XM_060507275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLL6"/>
    <dbReference type="GeneID" id="85391174"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="59303" checksum="4DFA743020827881" modified="2024-05-29" version="1">MVMSAFDRFIDSQFAKYDPGKTLTLYPHKVVDPYGLDLYDNPPKLAVPEGHLRDFDPKAHSPKTHGSVEVIELLSGGTAGGAQVLLCKVLKQPAEYRPSHAPFPEPQRYVVAKIFDPMFFPGDDEVLSALVGNDVLAEQLLSRESGAYEYLYDRGKPKPPPSDSKAKGKKQETRNTITGHPNLIPQYYGTWAIRFRMGNGKYREAGLVLMEYIEGHAIEELCDRDEDSGYLLPVTEEVIFHDVAGSASTTQARKVKLTEPFRLKAFREILHQLVVHMHISVEHADFIPANVIITLRNHGGINGVRELDEPRPVLLDLTLTKVWRKTKDAQGPGRERHCLEWLPNPPHPMERASPQGMELYIGWFDAEWSKERFDEWLVQEFGPLEEGSEEGSTGKYSTFATLDNLKADYFEKRDEEAKEEMRAQQDEAIRLMASASRKASDERAQDSQSRANPPSTSRRQQNRSDESTSTESGEEGIPRSLYRKLQEAKLAASESSFGGSPSPRLTPRSAQKSVENEEEMDTIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XME5</accession>
    <name>A0AAD8XME5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Outer spore wall protein RRT8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_602981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370120.1">
        <property type="nucleotide sequence ID" value="XM_060507200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XME5"/>
    <dbReference type="GeneID" id="85391099"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005619">
        <property type="term" value="C:ascospore wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005628">
        <property type="term" value="C:prospore membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="33710" checksum="1D69742D28991525" modified="2024-05-29" version="1">MSDERTVSQGQASSSGGRNRMVDSVQTKAQEVLQEDYDKARGLVADAAKSKAYLYPIKGIIYFATHRTLWKPLLSRIGSYLLLSAGVVTGMFVFTYVPQLALLVFVNGPLAVFTTVLLILNESSAIINFLSRSFLLQDAILDTFDGTLLLRDEDGIVREGRQLRPGSDPMQKLGKVLKSPFEKYSPKALIRYLIYLPLNFIPVVGTVIFISLQARSRGQAVHGRYFQLKNWSSSRRADWLKRHAGPYTAFGLVATALEMIPFASVLFTFTNAVGAALWAADIEAKDTSMTDSTAPTLRETAQKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMH9</accession>
    <name>A0AAD8XMH9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370074.1">
        <property type="nucleotide sequence ID" value="XM_060513478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMH9"/>
    <dbReference type="GeneID" id="85397376"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="59834" checksum="59BA7BE9BCE20D02" modified="2024-05-29" version="1">MTNSNSNDGTIGLGEVVFRTEETFRKLVDLANTTKSLHLQTRRQMNQLHSELHRTAALYRLVYLDQICHLETSSTTLRGLAPVDLNICRYSFRRANETLRLFEQSLVTAGPAETSLASPQYPKLLLETHRQVKALNDEVRADVVLAIKRVLNQDLFSRDTRAVQLRDIAVGRDPSLDHDIWQIRIQRGEAPLIASLLLASDDTRHTPGVDGVDGVSVTASCLRFRDANTIVETRALPRDDPDICRKTLKLASLLHATRSPYLLHCTGFRVLAQNRVQDRERARDQRLEYFYDASPLHGCRSAEIHRLSEHLGSPTGHFTRGRREAAARILSDKIRFAGQLARALSELHAVDRVHGAVRAENVWFGVRGGEYEAKVSVPLLVGAGFEEGEVRRCRVSGGGEDRGDGGEALEEGKRRDILALGVLLLEIGLGRSIAEVAFTSASATSSSSTASSLGGAGSGVGVGAVSAAEHLGTLNTVMGGRYTAAVRAALDPRQLAVAFSAMEAGGGAAGSGGGGKNEDEDEDESVFGKSSSCGLDRAFRGVVVDELLGVVGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMN0</accession>
    <name>A0AAD8XMN0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_423239</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Directly interacts with VCP. Interacts with UBQLN1. Forms a complex with VCP and UBQLN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370162.1">
        <property type="nucleotide sequence ID" value="XM_060502991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMN0"/>
    <dbReference type="GeneID" id="85386890"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23187">
        <property type="entry name" value="UBX7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0834">Unfolded protein response</keyword>
    <feature type="domain" description="UBX" evidence="7">
        <location>
            <begin position="309"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="205"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="448"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="498" mass="53039" checksum="11C0E9F34C4D44EE" modified="2024-05-29" version="1">MFFTGGLQEGIATALQQSKCVFCFVTDEEAESQTWETEYLTESSIATLLQDEAVALRLKKGSEEAGYLAAIFPLPNTPTVVVIKNGDLKEYIVAGTSKDEFVRRITAAFRGAQGQPAAAAVAQPAAASSAPVPAPAPAAQPTDDLYDETPYNPPRAAAAPVTTDQQPARPGTTSSSPRGPATPTQEEDNAATLRAVLAERGARLEAQRLESERKAKAARAAAAEKAETDNSKQAEQTRNHKEALKKARQEAADEKARILRKIEDDRAERRAKAAERAALRTQAASPKLGEVAAALTRSESSSLAPSSSAASGMTALQVRLLDGSTIRSRFPSAKTLGGEVRKWVESELSGSGSGGEPFRFKVVLAPRPSRLIDDTEEGKSLAELGLSPSSTLVLAPIGAHVGAYAGGSSFGEMAVTFLLLPLSLLQWLWGLISGVFSGLGARRAAAEEEEGAEPVTVREQRKGKFSQFANPDDRRGDHQLYNGNSLNFEPRPDEKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMN1</accession>
    <name>A0AAD8XMN1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_603380</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370226.1">
        <property type="nucleotide sequence ID" value="XM_060507223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMN1"/>
    <dbReference type="GeneID" id="85391122"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF23">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="143"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1730171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="45411" checksum="73977CF3B892109A" modified="2024-05-29" version="1">MSQATSTKCASRWVTRIIPIIITGTSGYATYVVVAYLGVDYLYRTRGEHGAAISTITLYLFFYLLTIATYLRTFLKIKADPGLVPLGPQAQQALRESNKKSRRRKEGDLESQPYFTGPDQDPDSPGLEGFYSKDIFVCESDGRPKWCSECRNWKPDRAHHSSEVERCVRKMDHYCPWVGGMVSETSFKFFAQFTFYCTCYCAVALGQTAYCLASQVRDGSVDGRTISGVAIAGFFGLFTFLMTATSWRFILLNITNIDALRKSWVHQLAIRVPNGTRPGNSYGLITYPLPKYPQGIPTSSDATVDSETPRDRLATRTFAIVRTEPDENPWDLGYARNWTSIMGYSLIDWLLPIRGSPCVNHDSMESDYEMGPLIQRLRERHSLPDPNGSSGGMEMQELRDSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMT9</accession>
    <name>A0AAD8XMT9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_715737</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC12A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370330.1">
        <property type="nucleotide sequence ID" value="XM_060511778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMT9"/>
    <dbReference type="GeneID" id="85395676"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055064">
        <property type="term" value="P:chloride ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055075">
        <property type="term" value="P:potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000013">
        <property type="entry name" value="Solute carrier family 12 member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="32"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="505"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="10">
        <location>
            <begin position="1206"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="602"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="904"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1045"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1045"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1273" mass="139564" checksum="247E633374D2A684" modified="2024-05-29" version="1">MGGDDRRPSLSSMEQTSTKAKLGAVSGVYIPVCLNIFSILMFLRFGWILGQVGLLGMLGLLVTAYLVDFLTTLSLSAIASNGEVKGGGAYYVISRSLGPEFGGSIGMLFYLAQVLNTALNVVGLIDCIKLNVGESFPQGYWTVYMLQTLALLLCAGLCLAGSGIFAKASNALLVILSLAIISIPISSAFKSPFRDDGLGVRFTGFSIETLVDNFAPHTKSESFKGFETFREVFAILFPATSGIFAGASMSGDLVNPSKDIPKGTLWAMMTTFIAYLVVVFSMASTTTHASFLNNTNIISVTSLSPPLILAGECAVTFFSAVMGLIGAAKLMQALARDKLLPGLLPFSKGTKRADEPIQAIILTYVLAQIAMFANLNQIATLISMGYQMTFFVMNLACFLLKIGSAPNFRPAFKFFSWETAFAGSIMSAAAMFFIDQTYAATAVCLLIFLFSLIHYLSPPKRWGDVSQNLIYHQVRKYLLRLRPEHIKFWRPQIILLINNPRSQTRLIQFCNSVKKGGLYILGHVIVTDDFNSGVHEARLQQAAWTKYISEFSRIKAFVQLTMSPTITWGIRNLILSAGLGGMRPNIAVMGFYNMDELRDSRPSFQVPKAPSSSNMNTRPQAKAKERPPRRRRGDTSARLMEGILPTDVMKTEGMMSVTSYMTMLEDLALRYKLNVAIGKGFENLETPRKDKANVKKHLDLWPIQMSAEVLSDGKSVLTTNFDTYTLILQLGYILYSVPTWHKVYNIRVMVFVEYESEVEEERARVKALLDKLRIEAEVIVFWLASGQLNTYELIINGQSNDLESQIMVHDILKDEEWWDDLQRFRGREPNLNSTEELTSFANIIESTAGRPGVFNPHVSLDDIESGRRPSLVHFGELPKKPTVSRLSRLGVSVGIHTSHLGDEVFEDASGSDGEISDQEQQPSCLDSDSEFEPGSSDYSEDEMPEVDTPRRPLLLGRGRGRSQSDDLLTSPSKQKRSKSNKSAAPAASYGTMVSQARSEGQAGPSHVGRVENVSAPPTPLERPALDRNISARSMGGFRSAGISTYDATSGSVSGKATPATRPTLSRQSSAVRFSSRPMPETRTDVEGVSGPTIMFADTTEEETPRAEQPAFSRQSSAGRFSSRPVPEMTVTAAEEFEPNSTFAEPSCRSRKASVASTADLGDVHMNMAELVGRYRLDSRPEADGPGSPYSTQGISLSFNDLPSRAQHVILNELMRQNSKDTAVMFTTLPVPTEGTCQDELASVQYLSDVEVLCHALPPVMLVLSNNMTVTVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN79</accession>
    <name>A0AAD8XN79_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_404591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370471.1">
        <property type="nucleotide sequence ID" value="XM_060502862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN79"/>
    <dbReference type="GeneID" id="85386761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="290" mass="32740" checksum="82A6292CDBCFD4F1" modified="2024-05-29" version="1">MAFSPGKARSVRRPWPWRLGRPGRKGLELFGPRVRDASFFWHTRVHAYVRYHGLPRAEGLPRPGLHIDHGPSLPCTACSRRARSQDMFRREPETLEMFLPFLGIELTCSLSVPVAGARASVGSHEKIEVDVFMRAGRRVPNADGTGRAAFGSDGRFWWSDRRRLPAAAKTAKGYRVQSAIGRPLRSTNRWKDASNHEDGGGGRRRRRLRSCRCPWAEERFSLAVEEPQDVVPLDSKVDPCHRLVWWCGVCCCDRGCDQPPGRLRERQLDKRCGVFGAGKCRQAGKNERGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNT0</accession>
    <name>A0AAD8XNT0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</fullName>
            <ecNumber evidence="20">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_600537</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 20">Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 20">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="18">Flavinylated by SdhE, about 5% flavinylation occurs in the absence of SdhE.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 20">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 20">Mitochondrion inner membrane</location>
            <topology evidence="1 20">Peripheral membrane protein</topology>
            <orientation evidence="1 20">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="20"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370814.1">
        <property type="nucleotide sequence ID" value="XM_060507038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNT0"/>
    <dbReference type="GeneID" id="85390937"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000001">
        <property type="entry name" value="Mitochondrial succinate dehydrogenase flavoprotein subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.40:FF:000002">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000482">
        <property type="entry name" value="Succinate dehydrogenase complex, subunit A, flavoprotein (Fp)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:001062">
        <property type="entry name" value="Succinate dehydrogenase complex, subunit A, flavoprotein (Fp)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.100:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase flavoprotein subunit (SdhA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.40">
        <property type="entry name" value="succinate dehydrogenase protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF51">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000171">
        <property type="entry name" value="SDHA_APRA_LASPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 20" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 18 20" id="KW-0274">FAD</keyword>
    <keyword evidence="6 18 20" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 20" id="KW-0813">Transport</keyword>
    <keyword evidence="5 20" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="21">
        <location>
            <begin position="58"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="22">
        <location>
            <begin position="509"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="63"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="452"/>
            <end position="453"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="19">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00059077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000171-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1730759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="643" mass="70348" checksum="9F3E3AE476322E21" modified="2024-05-29" version="1">MASSMALRRFAAKPAFSQARAFSTTRSAARIYANQHLRAKEASPYLSSKYPVVDHEYDAIVVGAGGAGLRAAFGLAEAGFNTACISKLFPTRSHTVAAQGGINAALGNMHEDDWRWHMYDTVKGSDWLGDQDAIHYMTREAPASIVELENYGCPFSRTEDGKIYQRAFGGQSQKFGKGGQAYRCCAAEDRTGHALLHTLYGQSLRHNTNYFIEFFALDLIMQDGECRGVVAYNQEDGTLHRFLANHTVLATGGYGRAYFSCTSAHTCTGDGMAMVARAGLPNQDLEFVQFHPTGIYGAGCLITEGARGEGGYLLNSEGERFMERYAPTAKDLASRDVVSRSMTMEIREGRGVGEEKDHIFLQLSHLPAEVLHERLPGISETAGIFAGVDVRTQPIPVLPTVHYNMGGIPTKYTGEVITVDESGNDKVVPGLFACGEAACVSVHGANRLGANSLLDLVVFGRAVSHTIRDKFTPGTKHKPLAADAGAEAIETLDDVRTREGSRTTSDVRLSMQKAMQTEVSVFRTQESLDEGVRKMTEIDAQFPDVSIKDKSMIWNSDLVETLELRNLLTCASQTATSAAARKESRGAHAREDFPDRDDVNWMKHTLSFQKNPHGKVDLGYRGVIANTLDENECKAVPPFKRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP03</accession>
    <name>A0AAD8XP03_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_600619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370839.1">
        <property type="nucleotide sequence ID" value="XM_060507044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP03"/>
    <dbReference type="GeneID" id="85390943"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001442">
        <property type="entry name" value="zinc finger protein 696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="96" mass="10908" checksum="69F4E94CDE25F211" modified="2024-05-29" version="1">MHSRTHTGEKPLKCEVCGKAFGESSNLSKHRKTHNVKGAFKCDFCDKDFHRLDQKRRHEKIHRKVAVALKADNPTPSIKKTQGGRVTKAGDRRNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPB2</accession>
    <name>A0AAD8XPB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPI anchored protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_599721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371099.1">
        <property type="nucleotide sequence ID" value="XM_060506998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPB2"/>
    <dbReference type="GeneID" id="85390897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599:SF2">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39599">
        <property type="entry name" value="GPI-ANCHORED PROTEIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042251920" description="GPI anchored protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="45581" checksum="06521CA1A14A9C5F" modified="2024-05-29" version="1">MRSHSLLGLPSSLLLLTAACINAEHPAVIRKMSPNAGEKLLPNDLAFTPNDVFGTINTTPLSPREELLAARMANDNFLSNSSFSYRPPFAEHHDSLTSTGWESLRRAVEALHILEKRQSCPTTMNSCDYIGAANKCCLSNEVCVKVVDEHVGNVACCPKGAACSGAVAACPSGTTSCDAELSGGCCIPGYVCQGVGCVPSPPPATSASPSQTATGTGGGGGGGGGGGSGSTGGGGGGGGAGTTVVQTITTTSVSTTTLVDGRTTTVHVTVIVTVGGATTRRTTTSTTAEEPSTTAPEPTTTTTGTAVPPFRPTSTNSDEPPVTSAYCPTGFYACLARAGGGCCQTGRDCATTSCPPTESTTIISNGVTVVVPLTEVPEPQATETCASGWFLCGSEGGPVPGCCPSGYECGTASCSSISPTRTGEIQKHFPNSGDSRVVVSLAVMVISLMVALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPJ3</accession>
    <name>A0AAD8XPJ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_565409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371201.1">
        <property type="nucleotide sequence ID" value="XM_060503752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387651"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105">
        <property type="entry name" value="DIM2-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105:SF1">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="941"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1395"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1454"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="742"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="908"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1517"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1535"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1553"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1570"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1607"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1686"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1768"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1787"/>
            <end position="1796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1796" mass="195869" checksum="BCCC07FE98E2B269" modified="2024-05-29" version="1">MGVDSNKPPPLPAPTETDSITPTELATDVSRPNDDASHYSLPDDGTPVTIKTRGHRANRSQTSLLIEYFEGGKPGPEGTVERKPSVRVRLTPSKKHRGDHIQITETKGNTRKTSLTRRVPLPSTTATSSHLDVEALEGEDADSMRSYASATEESNVSRNPIDIEIDHRGGRRRRPASPLIPDADAQSSYLAPNMSDISAIPQDSFLDGSGSTVLTKNSERRSKSTSRGNELAAGVTGALAGAAIVDHAKSSRSKRHSGERKVSGERSSRDKDRKHRSSKSRTSSVSEKQSEGTRSPRRRSSRGHVDSVLSGADSSLLSSSISPSHRSYDQSSVRSGASKSSINNPKLLETVEDAIRRLILPELSALKREQSKRESRRSSITSTGTGTSLSREELGVDRRKSADKRSEAGRDSRHRERRDREARHDYVDSPRSVAGESVEESSIVSVDDTPRRSDGALKAAVGGAAAAGLAAAAMNAASPSSEDRRQRRRRRADGSARSRSVGREKYDEEFHEEEVPAPPMPLMSEINPSEMTRTSILSADTDRPHSAMEERASVQEVARGNASLGSSPTPTQAAPMTNLQQTLGTKHANISHGDLRELSRSRTGDFLEQSEVSEFSQSPSSQIRDEYDDYDDRSRVTESEGDYVDSGDYDYYNTQDVPPPLKYVPYQPERRGLSPIYSVSGYTEAGSETAAQRDSRMSHGTASPTKSQASHTDLRAFSPASVPSNVMSRGFDEQSVDDRSVRSGQDYRNSQYTEGSEIGTSTGQAVRGIAANPNIIHVPNGVESNVASLVDGSMLESQLTTGSGYDYRDSQVSYGNESNISYGPESYVSYAKDSNVSYDDQSNIQPRSRDVSPEKRSVADQREFFEQRERESSRTPTSSRQSHRSREFAGEYDLDEYGRKVAPARYRNSPSTSTRHSPTASEKAIAAGAVGAAAAALKAAKDKTKQPTVEEVDEEHAEEWVPEGVTRNKSFKQRAMEGREPANTPAHSVDRLDLEDKPKMGASAMPTFDDPMPEVGYVDDDALTNPSLVREPLGGSDHNDGDHWPGDITPRQGTPRQSDYDQSYEEYNSEKHSPRGHGGYGMAAAGAAMGAAAGAAMAHHRQASGEHEDEWRRTSAERKRDTVITNPYDGASPVDHPDLLGGRGFEDYAAGYHANSPGGHKNLDEGYISQGPIHSPNMQPTSKAMMPFGDMNAEDPFFAPQHSRHLSGLSQGMNSPLYDAATGNGIDRIESKDIIALMQHLMVRDAQRSARDTEILVTLVRSAAEMRNSFDDLKKLLANTEDVIIKEVQENTDETVKNAVAGSRAYPGSLPRSVKGYSAASQNSTLDETAKKSNFFRKALKGLSNKGANDLSRIEDMLMQLLGEVDTLKAQTMRPGIVSGRPSYENLTPEMQYEQDRGYEPEGQAGTSTTSQGSHSGMSSFAQSRGPSKMAYEPNRISTVHEDNEEDYISQNNYHEPQGMLTPTREFSRGGSVPLGTPPQPMAAQNASLSNDNTPKTDKGKKHKRGSSSWFPKISRWSESTATSVSKAFRGSGSSKKEHEDEFLQHPPSRSGSDLRYDDRYQNEFGGSDQLHSGFSQQDLAVPQPPHLDPPATYMTPEDPKYKAHRNSVNLQHPQPRQGQTERFKAALESQAYDYDTPMSPRSADWAGSATSLHRFPPNANSYSNGSPATGGDYYASSSPAGPPRPPKEPMDEMTHTPAKKRISNLALKSSPLPYNSVESGYGTGPGTHAASTSNYTGSPKPENRNLSGARGMPARRPSGPRAMTPKSAEEEAAREERRRKRDTFGTVASNETDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ01</accession>
    <name>A0AAD8XQ01_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_160232</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371513.1">
        <property type="nucleotide sequence ID" value="XM_060501390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ01"/>
    <dbReference type="GeneID" id="85385289"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148017" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="24859" checksum="37CC9793D74694D2" modified="2024-05-29" version="1">MHPQRAIQILALASVAQASWFNFNKAEPRDGLLKRQSGTASGAETTSTAAAQTTTSAAAVTTTTTAAPVTSTTVAIVTTTTLRTSTTSAGSNNDETTSASAASSTHSTTAEPVTSTIKTIITTTNSAGVATSFTSEATVTSTPGLNEANSGDSSSGMSSETRKTVIGVVVGVGGAIVLGALGFVAWRIWGKKKQAEENDGLMEYNNQYGNEPKNEIGSAQGSGSGRTPFQSTLESYHAPNQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQI9</accession>
    <name>A0AAD8XQI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_596172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371744.1">
        <property type="nucleotide sequence ID" value="XM_060506854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQI9"/>
    <dbReference type="GeneID" id="85390753"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042042724" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="17790" checksum="22CA70C214EF396F" modified="2024-05-29" version="1">MWVSSLFSLLLGLCRVTVFLDPMLGLDPWPPTRPSIPHFPFSFLFCQYAVSVSACYLHRSTSGDQCLCFALPAGAHSFQLHPTLLIALRLLSLSEYLRSRDGAEDPSPGSGFPVAILIESLLLCLSLACFFQQIQPFFLTQTGLTTVSMIHRVGVSLVGGSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQV1</accession>
    <name>A0AAD8XQV1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhamnogalacturonan endolyase</fullName>
            <ecNumber evidence="4">4.2.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_687080</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non-reducing end.</text>
            <dbReference type="EC" id="4.2.2.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide lyase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.23" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371846.1">
        <property type="nucleotide sequence ID" value="XM_060511276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQV1"/>
    <dbReference type="GeneID" id="85395175"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102210">
        <property type="term" value="F:rhamnogalacturonan endolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10317">
        <property type="entry name" value="RGL4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10316">
        <property type="entry name" value="RGL4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029411">
        <property type="entry name" value="RG-lyase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016590">
        <property type="entry name" value="Rhamnogalacturonase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015364">
        <property type="entry name" value="RhgB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36574:SF1">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14683">
        <property type="entry name" value="CBM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09284">
        <property type="entry name" value="RhgB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041935148" description="rhamnogalacturonan endolyase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonase B N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="15">
        <location>
            <begin position="282"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="14">
        <location>
            <begin position="370"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1731791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="58918" checksum="C4E40179AB98810D" modified="2024-05-29" version="1">MLLLSLLCSLFFLPAVVLAAFGWTDNGSEYVIDSGSGLVIKVTKCCGDISSLNYKGVEYNGWGGKNTHVESGLGTSTVSITSYSNVIKVSVVHGTLKHWIFVRYGNNNVYLFTNKADDSVSAMRYIVRIPGGIFSHDSTESDFYDASSTIIEAQDINVNSAGLTKSKHYQGSNYGRVMDFDYVGRKKTGVGLFMIRSNHEKASGGPFFRSLVRRADPTGEDLYDIYYYNMGHTDPMRTGLQGPSVLAFTAGEDPNSNLFARKADWSWFDDLGLDGWVPASGRGYASGVGLSNMKSGKTYVVGLSNSAAQYWGTAGSGGAWSITKIIPGTYTLTVYKDELEVATSSVTIKAGAGTAVNTITCVDPQDDAVIWRIGEWDGTPKGFLNFEDTPMKPTYMHPSDTRISTWNAGNFIVGTHSANRFPGYMWKEVNSGYLIYFKLTTAQLAAGHTVRIGITEGYIGGRPAINVNSWASALPAATNQASTRSLTVGTYRGNNVKLTFAVPQSAWIQSTSEWQILTINIISGSSGEKYLSPGVSFDALELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX2</accession>
    <name>A0AAD8XQX2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_746218</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371861.1">
        <property type="nucleotide sequence ID" value="XM_060513233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX2"/>
    <dbReference type="GeneID" id="85397131"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF165">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="11">
        <location>
            <begin position="7"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="12">
        <location>
            <begin position="277"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="9">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="400" mass="41521" checksum="B1D6D2F7A892F1EB" modified="2024-05-29" version="1">MANLPPVYIVSAARTPVGSFLGSLSSLSATQLGAHAIKAAVERVPQIKPEDVEEVFYGNVLSANLGQAPARQCALGAGLSQGVAATTVNKVCASGMKAIILGAQTILTGSADIVVAGGTESMSNTPHYLPVLRNGAKYGDQTLVDGVLKDGLTDAYGKKEHMGMSAELCAKEHEFTREQQDEYAIKTYQKAQAATEAGVFSKEIAPVEVSGGRGKPAIKVDRDDEVKNLNIDKLKAMRPAFIPNGGTVTAPNAAPLNDGAAAVVLMSEAKVKELGVTPIAKIRGWADAAREPERFTIAPALAIPKAIKHAGLTEKDVDFYEINEAFSVVALANIKLLNLDPETVNVFGGSVAIGHPLGCSGARIVTTLSTVLREKKAKIGVAGICNGGGGASAIVIESLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRA1</accession>
    <name>A0AAD8XRA1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_556693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371971.1">
        <property type="nucleotide sequence ID" value="XM_060503525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRA1"/>
    <dbReference type="GeneID" id="85387424"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="33986" checksum="9B4A39965BD7FCF4" modified="2024-05-29" version="1" fragment="single">SSASKPRRKKSKKSKRVKMRSKKSARWQLGEDVADILTGQFFRKVEVDELLTPDRLHALRLERESQGQPRRSSDTLRTVSTDGSETPVEPFHLQDLLSRIGAAGAKTSITPSEAMTPPELLDPSVLRDLPFKEKSPRRKKPVSKDEYEAEDPTQAVPPPPAKNPARFLPRPQAPLLPTIPEVVVTTPDVGGQSAKHSNRHARTFAPVDEDDFIFFQSTPFTFNHSAFKHGNIRFPKSEVVKGLKIDPDDTLDWTAFQMAILGGAGDLFSDPADFSQRTEAEEIADLTAWFDGFGFDSHSRLLTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZF1</accession>
    <name>A0AAD9CZF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gcn5-related n-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_789004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369363.1">
        <property type="nucleotide sequence ID" value="XM_060515689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZF1"/>
    <dbReference type="GeneID" id="85399587"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="25755" checksum="CDE2B426928723A1" modified="2024-05-29" version="1">MTALFPQAAYKIATPRLIIRSAVADDAEALCRLLSTPENHPFGGAQTNISPEIIRGRIERWGPDYASGKKAILMITIRETGELIGCGGFNCFETAEGETCDVALKRKRDEDEQRGGEEAAGDGVAGEARRLITPYLTDFGVVLDHRYWGQGYGREVLCGQVEFAVDGLGCSIVRVETEVENEPWRAVMRSIGLGGLETKGPVSYGEKNIGWIYKIDPSTWSDSRGDLKKSGKWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZJ0</accession>
    <name>A0AAD9CZJ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_716643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368915.1">
        <property type="nucleotide sequence ID" value="XM_060511867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZJ0"/>
    <dbReference type="GeneID" id="85395765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00431">
        <property type="entry name" value="cysteine_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057088">
        <property type="entry name" value="GLRG_09195_Thiored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF5">
        <property type="entry name" value="ISOCHORISMATASE FAMILY PROTEIN FAMILY (AFU_ORTHOLOGUE AFUA_3G14500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24470">
        <property type="entry name" value="Thiored_Isochorism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="461"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="844"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="867"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="881" mass="95859" checksum="D60121070CCA1445" modified="2024-05-29" version="1">MFPFDVTAMPTLPTRKGLLVIDFNNDFMSADGALPVTNGNELVTRTLELVEAFRKVGDIIWVRSEFDTYRLASGEQIWATDTIPKPKILESRARRRIGGTSKQAPEETFDADPEAFLSQPGPKVVRPGTPGADYPTAVKEAIGKRDINLTKSHYSVFSSGQLIQMMRVKFVHELYICGSLTNIGVHASAMDAATFGYSITLVEDCCGFRSDVRHNASLSKLLEVTGCEVMDSEAVIKKIKPKSESKPAAPSSPVVPKRIAEASGGKTPPSADSYKTKLEEQLANLSIKNSKSSASKPPISRPRRDLSGPGCATASDVLEVDEDAGSKASSTSDIELEPDSSPELKPEPAKKPAAMDDIIEVDDSPHATEPLCEGDTLVIHNILPSTLARGIFEKVRDEVSWQRMSHQGGEVPRLVAVQGEVADDGSMPVYRHPSDESPPLFPFTPTVQKIKAEVEKELGHPLNHVLIQFYRSGTDYISEHSDKTLDIVKGSYIANVSLGAERTMVFRTKRRDKDPFGPATSSGEASLQRQACRAKLPHNSLCRLGLATNGRWLHAIRQDKRMDRDKTPPELAFDGGRISLTFRQIGTFLDRDSTLIWGQGATSKTRETAQAVINGQCPQAVDMVHAFGTENHSSDFDWDKYYGKGFDVLHLSTSPRLCASADPVINMRIALMLAEYGISYGKGSISPSFNWKDSNAGSKDTTAVSASLPIRFVDNDVAKSTVQGELAIMLYLDSVHGPGKKGAADRAQADVARTLTRFQDGLALLNKWRGLEKDSKSGKADLAPLKRELATWEGYAGEADFIAGSSMSLADFADATTETLEATKKLKVYYERIRSTESATKVLDAAQPDAAETVSADPKTEDVIEASKPSESPSGKKSQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZU5</accession>
    <name>A0AAD9CZU5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mandelate racemase/muconate lactonizing enzyme domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_607201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368901.1">
        <property type="nucleotide sequence ID" value="XM_060507414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZU5"/>
    <dbReference type="GeneID" id="85391313"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050032">
        <property type="term" value="F:L-rhamnonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03327">
        <property type="entry name" value="MR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000005">
        <property type="entry name" value="Putative L-rhamnonate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023444">
        <property type="entry name" value="L-Rhamnon_dehydrat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046945">
        <property type="entry name" value="RHMD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011968">
        <property type="entry name" value="PRK15440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794">
        <property type="entry name" value="ENOLASE SUPERFAMILY, MANDELATE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13794:SF58">
        <property type="entry name" value="MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00179">
        <property type="entry name" value="mandelate_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00006">
        <property type="entry name" value="rhamnonate_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mandelate racemase/muconate lactonizing enzyme C-terminal" evidence="4">
        <location>
            <begin position="170"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="46568" checksum="CB8B9DD3F7941461" modified="2024-05-29" version="1">MASVRSFPSIKEIRTFVIGGVGSGGDYHNVKGGHWLIDSPISTPCSRWEQYRNSRTSWGINVLGSFLIEIEATDGTVGIATGFGGPPACWLVHQHFERFLIGADPRNTNLLFEQMYRGSMFYGRKGLPLAVISVIDLAIWDLLGKVRNEPVYKLIGGATKERLDFYCTGPEPSAAKTMGFWGGKVPLPYCPEDGHAGLKKNVEFLRKHRESVGPDFPIMVDCYMSLNVSYTIEIVKACEDLNINWWEECLSPDDTDGFEQIKRAHPTIKFTTGEHEYSRFGFRKLIEGRNLDIIQPDVMWLGGLTELLKVSAMASAYDIPVVPHASGPYSYHFVISQPNTPFQEYLANSPDGKSVLPVFGDLFLDEPIPTKGFLTTADLDKPGFGLTLNPAVRSKLISGKALLNASPERPLKSVEETEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D030</accession>
    <name>A0AAD9D030_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12 15">Catalase</fullName>
            <ecNumber evidence="4 12 15">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_690556</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="function">
        <text evidence="2 12">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12 15">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12 15">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4 12 15"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369722.1">
        <property type="nucleotide sequence ID" value="XM_060511306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D030"/>
    <dbReference type="GeneID" id="85395205"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1370.20:FF:000001">
        <property type="entry name" value="Catalase HPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF3">
        <property type="entry name" value="CATALASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12 15" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 12 14" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 12 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003395" description="Catalase" evidence="18">
        <location>
            <begin position="19"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="19">
        <location>
            <begin position="55"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1729667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="714" mass="78170" checksum="8FA4F7F66CB3C4ED" modified="2024-05-29" version="1">MHTTLLLASLGLATLSSAGCPFADPSNIKARTEDGSRGHISGYEIDDSTGDPYLTSDVGGPIEDQVSLKAGVRGSTLLEDFIFRQKITHFDHERVPERAVHARGAGAYGTFTSYGDYSNLTAASFLGATGKQTSTFVRFSTVAGSRGSADTARDVHGFATRFFTDEGNFDIVGNNIPVFFIQDAIQFPDLIHAVKPRGDNEIPQAATAHDSAWDFFSSQTTTLHTLFWAMAGYGIPRSYRHMDGFGVHTFRAVTDDGKSKLIKWHWKTQQGKASLVWEEAQIVSGKNADYHRQDLWDAIESGNGPEWELCVQVVDEEDTLKFGFDLLDPTKIIPEEIAPLQKLGKMKLDANPVNYFAETEQIMFQPGHIVRGIDFTEDPLLQGRIFSYLDTQINRHGGPNFEQLPINRPIGPIHNNNRDGAGQNFIHRNRNSYTPNTLNKGFPKQANQTQGNGFFTAPGRTNNGHLVREISDSFSDHWSQPRLFYNSLTPIEQQFLINAIRFETSHLESTEVKQNVLTQLNKISNDIANRVADALGMEHLQPDAQYYHNKTTQGLSIFGNKLPSIATLKVGVLASLSANGSVSQGKELKDAFAADGVLVTVIAEKLTDGVDMTYAQADATSFDGVIVARNADGLFNGNIKPSPLYPAGRPAQLVIDSYRWGKPVGSVSSALTKSATLGVKAGEGVYSAADVNTVVNSFKEGLATFRFTGRFATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D272</accession>
    <name>A0AAD9D272_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">deoxyhypusine synthase</fullName>
            <ecNumber evidence="6">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_646908</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370624.1">
        <property type="nucleotide sequence ID" value="XM_060510026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D272"/>
    <dbReference type="GeneID" id="85393925"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.910.10:FF:000001">
        <property type="entry name" value="Probable deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="362" mass="39945" checksum="474A061E2EA28466" modified="2024-05-29" version="1">MASQENPNAPPAAATDAVLVVSEEMPEGAQKVEELDFDDIKGPITAENLYNGMRFMGFQASSLTESIRIINDMAGCDFKRAWRDPESGDKTTIFLGYTSNMISSGMRGVFRWLVKHKHVSAIVTTAGGIEEDFIKCLGDTYMSSFSADGEGLRKKGQNRIGNLVVPNSNYRAFEDWVVPIFDKMYEEQEASKGTDDEINWTPSKMIHRLGKEINDERSVYYWAWKNDIPVFCPALTDGSLGDMLYFHTFKTSPGQLKCDIVEDIRKINTISVRAKRAGMIILGGGVIKHHIANACLMRNGAESAVYINTGQEFDGSDAGARPDEAVSWGKIKIGADAVKVYADATLVFPFIVANTFAKDKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2E6</accession>
    <name>A0AAD9D2E6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370581.1">
        <property type="nucleotide sequence ID" value="XM_060513414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2E6"/>
    <dbReference type="GeneID" id="85397312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF2">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="1">
        <location>
            <begin position="234"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="51883" checksum="AC9C0ADACB14BC2E" modified="2024-05-29" version="1">MITHPPTRVKREPSLTDDIDSYVHSILGDASSWVASGIPAFFQGFPTGTAVLSTLGISEGDLDAKPTQILNLPAYGNWTDEGWNVRIHGNVFKQPNISQSKVDDLANVFLIDVDIKDLPADQQAQARNVTESIFVVQQDDQNVTMNFVNDVSVRPGASGGAVNARGGAQSINLPYLTTAEGDFDAFVKLRNTTDSTGGHMLPGNATSSIQTLNMYANGTLTGNATAYLVPPTGFTIISDIDDILRVTKIYEPKEGLLNSFARPFTQWENMPQIYANWSASIPDFHFHYLTTTPEQVTRNYMEFIYKTYPLGSFDTRPLNFSDISATLSIRRFLLDKIFQTFPQRKFVLVADTTNSDVMKAYPALYKDYPGQVQCIFLRNTSATDSGNKFPYNTEGFKDIPQNNYMFFRVPDDLTNLDIVNGQCYNATIPQNVTFKTQGLPFGLGNAAGSLAPPSTWAVAVVMFGMSLAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3C8</accession>
    <name>A0AAD9D3C8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_564764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371600.1">
        <property type="nucleotide sequence ID" value="XM_060503678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3C8"/>
    <dbReference type="GeneID" id="85387577"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="596" mass="65130" checksum="FDFD2EA22CEEF0BB" modified="2024-05-29" version="1">MDHLSSSSSAAAGTTTYTQQSVSTFQQDVPRQTYTTAGTIYNPSNAQQLQPPVRRGRTLKWPAQGGAASELSLFPKSVLAGLPLKSQNLVTTPTSPRPPQIPKYSPLQQNYDRAVSPLTDYSLESPKELDVRSISSSSLMPSNSMDSNQASPVAAAMPTSVMKKHFDANSTDDEDDESSGENPLRGLTVKSLHNLASYPNPNQKRAQRALLRARPGATPAQSAGNISRTATPSYGAQAFESFDVGNDYSHSPALFHSAKTDPNDIFKMKADRSSHDPDNSWRSNCTGPPPGLFPAATIQRDLPQTAYKSTLATGPGAPRPLTAGPPGHRQYRTSTFENTVKALNNGPKEMPLDGPMLGQTNLGPQNHMALETIRFPGTETPVHLKSPLDSLLCGSTPDTDDCLQDVVEEARKVSDQQMEKVLEFIKLGQNMNEATSRAQAASAMPVVSSDEWQADYPKTARPPWTEGTWAITDDALQKRNERISQLFHAGTGALGKSMMAVIQEKEFRDFKRQVGVIGDRRPKSKVEKTEYPPIKVAQLNNMSVSEATEPFLTMAYAALVNHQEGVHDHPQFHQWEDPEPHMVDTSAQGLRSVFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Q7</accession>
    <name>A0AAD9D3Q7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Homocitrate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_597111</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371944.1">
        <property type="nucleotide sequence ID" value="XM_060506884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Q7"/>
    <dbReference type="GeneID" id="85390783"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004410">
        <property type="term" value="F:homocitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07948">
        <property type="entry name" value="DRE_TIM_HCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000032">
        <property type="entry name" value="Homocitrate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048253">
        <property type="entry name" value="DRE_TIM_HCS_fun_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF48">
        <property type="entry name" value="HOMOCITRATE SYNTHASE, CYTOSOLIC ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="4">
        <location>
            <begin position="64"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30294" checksum="A471EA8A0F2DD43A" modified="2024-05-29" version="1">MCPTPDVPASNGHANGTNGHANGNGAANGTNKADHPGFTAIPTKQKHSNPYQPVGDFLSNVDRYKIIESTLREGEQFANAFFDTETKIKIAKALDDFGVDYIELTSPAASEQSRKDCEAICKLGLKSKILTHVRCHMDDARLAVETGVDGVDVVIGTSSYLREHSHGKDMTYIINTAIEVIQFVKSKGLEIRFSSEDSFRSDLVDLLSVYSAVDKVGVHRVGIADTVGCASPRQVYDLVRTLRGVVSCDIETHFHNDTGCAIANAYCALEAGATHSEFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U527</accession>
    <name>A0AAD8U527_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_594968</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000266">
        <property type="protein sequence ID" value="KAK1704311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357418.1">
        <property type="nucleotide sequence ID" value="XM_060506752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U527"/>
    <dbReference type="GeneID" id="85390651"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1704311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="29475" checksum="20784C7CE8F3B196" modified="2024-05-29" version="1" fragment="single">RALIFVSLTSYIPQYHRLREQGHCNGLSLYYVLFNLLSVTEQLTIGLFLNVNNGASLRPDAFVNTPATAGDWLNLGQLMIVWLCSLYLFTLSIRKASQSPEKRIQRGAAITSFVVFLFFSIFPVLIDASLPSSRSEPRRWAQDIFALLHYVLLIPLSTAFIIVAAVPQAREIRSRGGNAGALSLPGLAIQCITFTLVAISWVFRVKYPPYSPSWVEWYRLIGWTVVNDSLAGCVRGFLLVIALREGMDEGWGPFERQPLLSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6B8</accession>
    <name>A0AAD8U6B8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_798274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000307">
        <property type="protein sequence ID" value="KAK1702564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357153.1">
        <property type="nucleotide sequence ID" value="XM_060515925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6B8"/>
    <dbReference type="GeneID" id="85399823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045564">
        <property type="entry name" value="DUF5910"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19287">
        <property type="entry name" value="DUF5910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1702564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="17917" checksum="BB80B91E02C7BF77" modified="2024-05-29" version="1">MPRKIRREGSCGSQVGNGIYLGSEPAGWRGSPIKKNWYCVFKADEARFNAASKLWIPQFYTSKSFWGSSKPKELWGYGEKLIAKYIAKFGFSASSTLRFSYIEAHGRTLQMVIPTKMANADTLDIYAKCFETKSELIAYESESVNFWDWAIKGDPGNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6W9</accession>
    <name>A0AAD8U6W9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_594884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000260">
        <property type="protein sequence ID" value="KAK1704652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357453.1">
        <property type="nucleotide sequence ID" value="XM_060506745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6W9"/>
    <dbReference type="GeneID" id="85390644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07267">
        <property type="entry name" value="THT_Oxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000034">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000039">
        <property type="entry name" value="Trihydroxytoluene oxygenase (AFU_orthologue AFUA_8G02470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="161"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="39506" checksum="DCCE4F29D82D5E61" modified="2024-05-29" version="1">MPDRKIQLVRLAHVFYKHKNIEEARKFYDDFGFYELERKGNKTFYRGYGTEPFVLCAEEAEEDEFGGPAFVVESLEDLEYASKTLPSATEVHDLKDVPGGGKCVTFKDPVDGWPLHLVYNQTPIQRRDPGFPNLKFNFPEEKHRDVNKKQRFTKRPAPVHKLGHFGVCLTNFDKAYEFYTSNFNLYPSEASIPGLVHAPDNKDKSVTVFFRLARGKEFVDHHCFFFLEGPKFHVHHSSFETHDFDTQVLGHDWLREQGHTLCWGVGRHIMGSQIFDYWFDPSGFIMEHYVDGDLLDDTEKTHHTPAAPDNLHIWGELEPYPKDITYANRCGTGPEVPATFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7J0</accession>
    <name>A0AAD8U7J0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_594845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000258">
        <property type="protein sequence ID" value="KAK1704780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357479.1">
        <property type="nucleotide sequence ID" value="XM_060506739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7J0"/>
    <dbReference type="GeneID" id="85390638"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000051">
        <property type="entry name" value="Glutathione S-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF263">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="118"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="29735" checksum="4F1EC7958C426ED9" modified="2024-05-29" version="1">MAETPSAKRQKSSKDVSYELIYWPGLPGRGEHVRLLLEEAGAEYTDTAQIEDGVKSVLAQIDDKNLGDEHNPPPLAPPILKHGDLLISQTPNILLYLGPRLGLAPKISEDDDGIYIVNGLALTALDGLSNEAHDTHHPITTGLYYEDQKEESKLKAKDYIANRLPKFFGYFERVLKSRASGEGPWLYGGYLTYADLVLFQQCVDGLKFAFPNALKRIEGTGDYKGLFALYDAVKGRPKIKEYLASDRRQKYSQGIYRHYPELDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7Q1</accession>
    <name>A0AAD8U7Q1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_593579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357902.1">
        <property type="nucleotide sequence ID" value="XM_060506641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7Q1"/>
    <dbReference type="GeneID" id="85390540"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="5"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1706774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="43806" checksum="D0F6B636F2E7BEB3" modified="2024-05-29" version="1">MTSFEERIDTAVRDRDIPGIILHAQDKSGSFQYSHIYGDNLKSSSPLSDDNILTLASVTKLFTTIAALQLVERGFLTLDGDVSKHIPILAQKPVLTGFTESGKPIEAQCKKPITLRHLLTHSAGNSYDFLSDATREWQSYHGLKPTRGSTVEERFGYPLNYEPGEDWAYSCSSDWTGRLIENVSGKSLEKYMRENIWDPVGASSFTFDVESVRSKLWGMNTRDRDTGKIILHRGRELNHGVTDCLGGQGSYGSTPDVMRVLHSLLVDDGKLLSPASTSEMFKPQLSSQAKSSLLKAMEEPEWAVGHFPVTGEYDWGLGGLLVDGHSHPYRRNATLMWSGASNVFWWIDRHAGLCGFFATQMLPAAEEGVRPYIKAFEDEMYSRARGTKTRAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Y9</accession>
    <name>A0AAD8U8Y9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cornichon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_589411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359686.1">
        <property type="nucleotide sequence ID" value="XM_060506230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Y9"/>
    <dbReference type="GeneID" id="85390129"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1713360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="16143" checksum="8BC8BB830B4034FC" modified="2024-05-29" version="1">MSGEAWLYLFAVLINAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIIPEAAVHGFLTFMFLINGYWVPLILNLPLVAYNVKKIVDNTHLLDATEIFRKLNVHKKESFVKLGFHLIMFFFYLYSMIVALIRDESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T4</accession>
    <name>A0AAD8U9T4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_190371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000222">
        <property type="protein sequence ID" value="KAK1706757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357885.1">
        <property type="nucleotide sequence ID" value="XM_060501589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T4"/>
    <dbReference type="GeneID" id="85385488"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="24654" checksum="5F7056ADF24E3765" modified="2024-05-29" version="1">MALSDRTERRQHEFRSGGTSKNDVLRLRFDDFSYESRISSGPQAHQMRPMPPPRSRASWAFPLRRGSAASGGFDCITADTTLTTSTISSDGAATEPPSSGIMKTMEFQLSYEARTWTTSRRGRMIPRDESMTLRPSTIAEMRRVTSGEVPLLHDGMSPTSRDHDVEAGFTRTSFNNRHSSPPGSPWEWMGNRQVRPLSMNGGKLGAEATHTTTAEKRLSTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Z4</accession>
    <name>A0AAD8U9Z4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358798.1">
        <property type="nucleotide sequence ID" value="XM_060509500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Z4"/>
    <dbReference type="GeneID" id="85393399"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415:SF3">
        <property type="entry name" value="GNAT-FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43415">
        <property type="entry name" value="SPERMIDINE N(1)-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="112"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="30229" checksum="D78BE849206B89E5" modified="2024-05-29" version="1">MDRVEIRAMGRLSHCTNNRYFRLDAVLRVVPFIPNCFEQSYLLRHHEHTFATTMLTDDLRGAYRSERLTFRAVENNDDDKKFLHTQIENDPVTVALSNPMALMPRTSKHSEWMVEQMAKSVLAVIVCLPANTPGDGDEEAGEAKTTAPKPIGYLAIGWGGIPPAMAHHRSVGLGIAIAPQYQGKGYGAEVINWALDWAFRYGNYHRVHLGTVSYNERAQHLYKKLGFVEEGRSRESYWFNRQWHDMISYGILESEWEAMRGIKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAH9</accession>
    <name>A0AAD8UAH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_712397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358245.1">
        <property type="nucleotide sequence ID" value="XM_060511611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAH9"/>
    <dbReference type="GeneID" id="85395509"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123:SF3">
        <property type="entry name" value="NODB HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="81"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="38321" checksum="4B5889AAE013079D" modified="2024-05-29" version="1">MVHVEESLQIPRDFEGFGEDGFDPKWPNGARIAVSFVLNYEEGGERSTLDGDPFSEPYLWEKGASGGYKEGARYLNAEQDFEYGSRSASWRLIRLFKEFGWSFTTYAVAYALKRNPTFAKALVRDGHEIACHGLRWLDIWNYSLEEDKEYIKQNILMLKEISGEMPVGAYFGRGTPNTPSLFPEVWKSLGGEFLWSSECYNDDVPYWLDLPWEEKLPEEKREGMLLIPYNYDCNDGKFHMSPGFGSSVAETYEQYLKNTFDCLYREGGKLMNIPLHTRIIGKPGRSEALRKFMKYVAEKEGVWVTTRRDIAKHMRAEFPYKPNREWMKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAI4</accession>
    <name>A0AAD8UAI4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_657735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000211">
        <property type="protein sequence ID" value="KAK1707338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358026.1">
        <property type="nucleotide sequence ID" value="XM_060510985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAI4"/>
    <dbReference type="GeneID" id="85394884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="146"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="59689" checksum="EDC598F42AA46649" modified="2024-05-29" version="1">MAGETPDADMHSFPPNSSSSFPRILISDHSAAECTTPFLSYNGLIDFGNTVLPPGGVPEVQDSDHLISQFMNNGLVPSMLQVKMEGIQSQNGLNCWFAPWSLPVGGAADIMGESPSSPLTQTLPSPQSSISPASTVSLGRSRVITEQEWEARKPDIEKLYMRDCLSRQATERIMAEQYQFFASSRQYKGRFQKWKWRKNNTKAVRQDILAGRSFTISNGPTPRRPGRLQSKTKKDAKAIPSPMPNDLHELSTTLLQCMRDLIHRSWKEDAVWTQPNRLGRLPVYGQELTSRVAVGLEHLAFQDTLNGFSAIRHMFRGLDDLVKKSDITIYATLLLDIPSTFYEFKGELLDERRLLKIYFLYLQCLLNQYSKGSSPLADAARAMAQLTDKYYDEAQACLHQLYRVVADSYRDIQGCDTFDNIEWRIEAMKAVGGTSDTAETENIIIALANMQFLAATNQGSLQSPNLIEYELWKIELLRSIEPGGKFMDRCNRLLNRIKSAAIDKTWRLWGSWLLWISGEILRRRWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAJ7</accession>
    <name>A0AAD8UAJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_723813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359143.1">
        <property type="nucleotide sequence ID" value="XM_060512600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAJ7"/>
    <dbReference type="GeneID" id="85396498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="42116" checksum="3FC0B7329E0D8E01" modified="2024-05-29" version="1">MDVIFYASLGAPDFPSVKNSTPKLLRNMGGGSSRPSPPPRVPKTLPSTTIWVQHLPPLISETTHQVILSIGQIRSQYLMGAISSVDSEDLRSLIERLDVLIEDAHLSANIRDYIRLCTEETMLRLLTDRKPISQTLFEVARAVNPFLGSQGIDVGKLKAGSISAGDDNLPIPFRPSDTCLIDESEKDLLVLLYYCDVALLEGSIEEALAQLLKMAKKYGTIKDLDLRRESLSETEINIHWILFYLENKISLAIAAGGSPPESGAKLDFERSTRMSRLLTIGEMLLSEGRLDQVCFLLIPLRRCIAGQDKPWWRSRTRRLLKGIKKTRAGRQKWHIQVADKHLLCIKGLETDSGKSWGWRGSSTIRPETIEMGKVKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBD3</accession>
    <name>A0AAD8UBD3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359638.1">
        <property type="nucleotide sequence ID" value="XM_060514803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBD3"/>
    <dbReference type="GeneID" id="85398701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="278" mass="31408" checksum="43371A0C83ED3B85" modified="2024-05-29" version="1">MASVECAVRMMLMTECETEGTLAIGSRNVYRWGGSETLVDYLNRIYTQSTSSDVSKDPVDLKKLRCHVLARDAGVKIQQTEKLSDHLNLVCRPRTKVLLVFSHKAFLEHSLEIVKATRPDLTHTTHEALALGCLPPKLMDETLRTYNLLFPLIGSTKSKKLWNGWVKRENLDASLLKASSGLSKKGTPRTLHDLYEGFPHWAPQLARLLEEVDDPTPTTRWERYAERRRSHRHTYKCAIAALVVAAVSGTLATLLAAVQVWISYCDWAKELNKPLCRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBK4</accession>
    <name>A0AAD8UBK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/polyamine transporter I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_724052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000172">
        <property type="protein sequence ID" value="KAK1710315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358785.1">
        <property type="nucleotide sequence ID" value="XM_060512618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBK4"/>
    <dbReference type="GeneID" id="85396516"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF5">
        <property type="entry name" value="GABA TRANSPORTER (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1710315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56294" checksum="D46D411B898FE4E5" modified="2024-05-29" version="1">MAPVVDTDRIGADAIGRRIDGADEKTLITYSEEYGEQQQPSGLERYINHSSVVNFGVIILASWESFAVTFQFALANGGPASMFYGSILAGFGACAVGFSLAELASIDPTVGAQYRWSANLAPSANRFWGLLQGWITTAAWCFACGGPPSILANIITSLAIFNYDNYTPERWHTSLIMIGTLVLPFLFNLWFRKFLNAFEIIGGVLHIALFVAFLVILAALGQRSSSDYVFKTLTSDISGWNNPGVSWGLGLLTITFSVTGFDSVIHMSDEVKKARTRVPRSVILACVVNSVMLFAFVTILLFYIGPLDDLSTAPLPLIYVIYNATGSKAASNALVSLVAVIIFFASFNMLASVSRLVWMFASDKGLPFSGFFSYISPTFKLPMNALLLIAGIVTCLSLIYIASATAFNALISLQALALHVSYFFPILFLLLRKIRGPPPPYGPFKLGAVGSQVNIFALSYLIYVVLWMPFPQILPVTKDNMNYAGPIFGAVLIGALVDWFVSGRKRFQMPLRKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBN0</accession>
    <name>A0AAD8UBN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine dehydratase catabolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_633464</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361051.1">
        <property type="nucleotide sequence ID" value="XM_060509037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBN0"/>
    <dbReference type="GeneID" id="85392936"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF6">
        <property type="entry name" value="L-THREONINE DEHYDRATASE CATABOLIC TDCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="4">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1718051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="332" mass="34193" checksum="9788AC0F21C2B365" modified="2024-05-29" version="1">MSLSIHEVAASAVQARSRIASHIYTTPLLPARTTGRDTNAKVLFKAENFQLTGSFKLRGATSKISASQATGSQNDAKLITASSGNHGIGAAHAAHALNRSLTVVLPETVFPAKLAKINALGATVILHGAETGLAEQHAQHLAASEGYTYISPYNDPLVVAGQGTIALEILEQCAAQGIPRLDNIFIAMGGGGLISGIGSVLKAFAPHVKIYGVAATNSQALAESIRAGKVVETEHLPTLAEAVAGGMDEDSITLPLASEVVDRVIGCSEGEIADAMKKIAVEENMIVEGAAALALAGFEKVKGEVEGQTSVVLLCGGNVDQGVVKKIIYGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH2</accession>
    <name>A0AAD8UCH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endo-1,5-alpha-L-arabinanase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_590390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359280.1">
        <property type="nucleotide sequence ID" value="XM_060506333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH2"/>
    <dbReference type="GeneID" id="85390232"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08983">
        <property type="entry name" value="GH43_Bt3655-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18828">
        <property type="entry name" value="GH43_BT3675-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046780">
        <property type="entry name" value="aBig_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20578">
        <property type="entry name" value="aBig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042211087" description="Endo-1,5-alpha-L-arabinanase A" evidence="7">
        <location>
            <begin position="21"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="Atrophied bacterial Ig" evidence="8">
        <location>
            <begin position="29"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="6">
        <location>
            <position position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1046" mass="112438" checksum="D5E8BA83CD272131" modified="2024-05-29" version="1">MQSLHFWLSSALALAATVRGQDDNTAKVEAALAAITVTNLDDVRGNLYLPSTIDGLNVTWASNSSVISSSGVVVRQAEDTQVALTASIDYEGSSQTRELVASVRKAVALDPFAGYAFSYFTGNSIAGEKIYFAASQGNDALQWTELNGGQPVLASTYGTKGLRDPFLIRSPEGDTFYLIATDLSIGSGTSWGDSVRIGSRYLEVWESNDLKTWSAQRHVLVSPPEAGNTWAPEAYYDDDLGAYLVFWASSLYEDSDVNRTGSTYHRMLYATTRDFVTFSETSVWQDAGMSRIDSTVIKSADTYYRFTKDEGASGTGCSDIIQESSTSLRATLDSWTIIDSCIGKKAGTSAVEGPTAFKSNPDDVHGEKFYLFVDEYGGRGYIPLETADIGNPNWTVSSSYSLPASPRHGTVIPVTAAELASLTGASATRRAVEAEGEILRYDFSATDGTQLQDASGNGNHAVINGGATVVDGALTFDGVDDFVKLPNNILSGVEDVAIEAQVLLDASQTTPYFIYGIGNTAADGNGNGYLFTTGSPYRASITTGNWTGEKSAASSSSLPTGSWLHLVYTISGRTSVIYLNGYEVARNEDVNIDPQNIGNGVTTANYIGKSVYSSDKLFKGQIREFAIFNRSLTAAEVLSRSGNVGAITEVSLSDASVLKVPAIINTTDSKVLFPVKPGTDVTALAPVFTTTEGVTSSPASGSTVDLSAPVKYVLSEGDEAVAEWTISAVEMGSPVLPGLYADPNVAVFNGVYYIYVTTDGVPGWGGNTFYLWKSTDLVTWTRSAEPFLTLDGANGNVPWATGNAWAPTIAERDGKYYFYFSGQNAALNRKTIGVAVADSPEGPFTAQPEAMILNNEAVTTGQAIDPAAFHDPVSGKYYIYWGNGSPLVAQLNDDMVSVNWDTAQLMTGLVDFREGLFMVYREGLYHLTYSIDDTGSENYRVGYATSKTFNGPWTYQGVILQKDTSQGILGTGHNSILNVPGTDDWYIVYHRFGIPGGGGYRRETTIDHLYFNADTGLAIPVIPTLTSVEPQTVPQKFRRMSRVMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD44</accession>
    <name>A0AAD8UD44_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_656740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000155">
        <property type="protein sequence ID" value="KAK1711885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359209.1">
        <property type="nucleotide sequence ID" value="XM_060510898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD44"/>
    <dbReference type="GeneID" id="85394797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041769197" description="Pectate lyase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1711885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="326" mass="33478" checksum="AD35F18C93A79855" modified="2024-05-29" version="1">MKYSFAIALSTLVLGITAAPAANGAAQGNAIAHAERGYFDFLHHAARAEKPTKTKSSKAAKKTKHSTKTRHPGSIITSAPGAPGNGTNSQFEIRASNGTAAAGLPASSGTSVLKAAQTVAAGASFDGGMKAFDRGVSCTGQAEGGDSDAVFILEKGAKLSNVIIGPNQIEGVHCNGGCTLDNVWWAAVCEDAFTIKNQDAGETTTITSGGAFGADDKVLQHNGAGTLSVSGFTVETFGKLYRSCGNCKSMYERHVILDNINASSGKLLAGINSNYGDTATFTNIVAKSVKEVCTEFKGTTPGNEPTEISSGPSTYCKYATSDIQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDA6</accession>
    <name>A0AAD8UDA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359715.1">
        <property type="nucleotide sequence ID" value="XM_060510865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDA6"/>
    <dbReference type="GeneID" id="85394764"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="38797" checksum="E14B66C0768ABAD0" modified="2024-05-29" version="1">MRLNASLVVALVAVVVVVLVIVLVAVIVVVLVAVVLVVLVVVLVIVVVVLVTVLAAAYSAALHTSLAAIFSAVHVTFLTARVVVLLMAKSSRSSQTQRAGISVAEDTAIFGLDDSLSTHQKRLQAATAFATLRGGIERNKTLLSTLTKRNAQRRRRDYFETNAKELVQSGDVSQILSPLVKLCSSHPERPIDWLLLALYSLTETCITNIKEQDLFDVFVELFPRAIGECSIFQETREMFIDVLRGICRQDTSIIAQMVAGGAVFQFVAARGDKLEGVLPGTSPFLQGIHTGRQWCWERQKDAESLSSDEMRTGAICAMIPDNDQADISFVLTVGYKAGWDIVQYLEFRSSEMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDB0</accession>
    <name>A0AAD8UDB0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_634134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360778.1">
        <property type="nucleotide sequence ID" value="XM_060509077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDB0"/>
    <dbReference type="GeneID" id="85392976"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="377"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1716848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="69681" checksum="C7859364DB996FC3" modified="2024-05-29" version="1">MKVLSRIDGSVCGAILSTRPCAARAAVSSRPELRTERPSRAPASQHHRDRTRCSRPPATQCPRTASWLLSTFLPAPFSVRPRTPTSSNSAIRGRTQSYSHVAASVITSASRSHHVVMRKDKDVLLGFVEHEDVGTVDEHLELARDPYLNRYAQPEPTPLTISERKEDQQYPSYHEALRGDEDIGQLVTKLGTAVSTKMRYPARVDLDTIHSLYAALPEPRMIHMPAKLRHRLLKIFGTPIKKETQTMLRYFSLIGDAKDCGIALRQSEWNHALALASRYVGRVTDTEAEAALQLWKEMEKLSGVKGNAVTFNILFDAASKAGNFALAEMLYEEMKKRGYSFNRFHHVSLIHFFGLREDPDGVRAAYKELVEAGEMVDTVVLNCVISSFLRCGDEDAALKVYGYMKDSYSAAAKIPQMDPLMDKAVIHIHSMFARVGQKIPELRPQLQELAHETPDMRTYRILIKHFAITKGNLSKTAQFLDEMPQFEVPVHGSIFLAIFEGFSKYGASPFSPWTGDRLENVLAALFEAIDNKVQGLRLDTWLMIWALRAFMKCTNNEKVLEVYEDFKKRWELAPDRADFMDHYLARLMDGKDAFIFQRGSGQHKKKHKAVRKRPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDF8</accession>
    <name>A0AAD8UDF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase II subunit 1</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">ATP-dependent DNA helicase II subunit Ku70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_709902</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359541.1">
        <property type="nucleotide sequence ID" value="XM_060511580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDF8"/>
    <dbReference type="GeneID" id="85395478"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00788">
        <property type="entry name" value="KU70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01458">
        <property type="entry name" value="vWA_ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000071">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.970.10:FF:000003">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.970.10">
        <property type="entry name" value="Ku70, bridge and pillars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006165">
        <property type="entry name" value="Ku70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027388">
        <property type="entry name" value="Ku70_bridge/pillars_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047087">
        <property type="entry name" value="KU70_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005160">
        <property type="entry name" value="Ku_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00578">
        <property type="entry name" value="ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF2">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03730">
        <property type="entry name" value="Ku_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003033">
        <property type="entry name" value="Ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 23" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="SAP" evidence="22">
        <location>
            <begin position="614"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity" evidence="20">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR003033-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1712925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="652" mass="72638" checksum="7A8A6F68A0B3BEAD" modified="2024-05-29" version="1">MADRGHFKREDEDEDDAEEELDETDFKAQKDAILLAIDVSSSMLQHPPATNSKKADRDSAVEAALKCGYHLMQQRIISNPKDMMGILFFGTEKSKFQEESGRAGLGYPHCYLFTDLDVPAAEDVKALKTLVGADGEEAEDEDEVLVPAEEEVQMANVFFCANQIFTTKAANFGSRRLFIITDNDDPHGKNKDAKSAAAVRAKDLYDLGVVIELFPITRDEKKFDLGKFYDDIIYRDLVAEANLSETRNSKSGDGLSLLNSLILNINSKETPKRSLFSNLPFEIAPGLRISVKGYNILHRQTPARTSYIWLDGEKPQLANGETTRIAEDSARTVEKVEFKKAYKFGGEYVHFAPEEQKSLKDFGAPVIRIIGFKPRSMLPFWASIKKSTFIFPSEEDYVGSTRVFSALWQKLLKDKKIGIAWAVTRVNASPILVAVIPSHEKSEDDSGTPYLPAGLWLYPFPFADDLREGPEPPSNHVVSSNELIDKMRIIVQQLQLPKAMYNPKKYPNPSLQWHYKILQVLALEEEYPEKAEDLTEPKYKAISKRAGGYLDDWAETLQDETKIALAKAAIKREADGGDDERPAKRVKAAPKAAKVSGSGMTTAQLKESAASGALSKMLVADLKDILAARGQSTAGKKSELVERVEEWVEENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDI0</accession>
    <name>A0AAD8UDI0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_723517</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359571.1">
        <property type="nucleotide sequence ID" value="XM_060512569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDI0"/>
    <dbReference type="GeneID" id="85396467"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1712955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="54152" checksum="55859B0552A6437D" modified="2024-05-29" version="1">MPKLPSLVPAAVAKPLYRGTELVRGAVGSLTWGPALSVAKPAILSVFSKIERGTLLLVDEPAELRRVFGQKLGAKYNENLTNGDHVPRRADAVPRVELVVKSDAFWMRLFLFADMGFAESYMLGEIECKDLTAFFQLFIVNREEMGNGTTWISSLSTAVSSLARTTNTLSNALLNISAHYDISNDMFAAFLSPDMTYSCPIWKPQSSADDPNEPEETLEQAQMTKLHRFIDGARIKPSDHVLEIGTGWGSFAIEAVKKTGCRVTSLTLSKEQKALAEERIEAAGFSDRIDVRLTDYRELETPGRPFDKIVSIEMLEAVGQEFLATYFAQMDRLLKKDGGIAVFQCITMPEGRHEAYSKGEDFINHYIFPGGYLPSITQLLNHISKESKGTLIVEKVENIGGHYSKTLRLWKEEFLRNFDSKIRPALKREHDDMTEEEIDVFRRKWEYYFTYCEAGFRTKTLGDAIITVGREGALELMEGIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDY1</accession>
    <name>A0AAD8UDY1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_73428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359984.1">
        <property type="nucleotide sequence ID" value="XM_060512940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDY1"/>
    <dbReference type="GeneID" id="85396838"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1714522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="707" mass="79139" checksum="2C11238BA600DF9A" modified="2024-05-29" version="1">MSLPAKRRRVILPAPGAQPSGSFPSTSSTLVATPAHQPSASGRGSIGGSGSSEESLLGNDTSRDLQSRSQSIDSSSADAKKPRTASKRQVIAVACDNCRRRKAKCDGHRPKCQHCSKRGVECHYEANQGETVSLALKRKANDLESENVQYRELFRMVCTKSEDEAKEIFRRIRLSGDPLRVLESIRQAEILLPSLPVNDRVSDSRLAKLNERAMESSLLRVPAKPWTTVADDGIVSELITDFFSWDNASCFPAIEQNLFLEEMRSGNIKRAKWCSPILVNAMCAVRAPFVATVKEFHTYTGQDLARQFREEVMQLVEKSHGRASIPTIIALVLVDWSASIAGDEASAKMYRFMAWERYKRFKPERRFAQLNKDDPNDAIEMLVISKAVWAIFLMESRVSYFYNSTADIPPPSIPRLFDNCGRDALEPLGNVDVLGRPHLESTNLIPIVPGIATVVCDLARLQYDVMSYLTSGSTIKGSIEDVRRKKHWYCRLQEFREALPRRFKMEYNFTPATCFLRMHENELAYAVLQSLSPSTIFDTPFTPHSTTVKSLCLQHCISDTTLAEAYLQRYCTHSYITRVMFVAMQHLMPYLNEGHAATNDLFTRLCMMGGISARVVRMSMYLLQAVQAMAWAMKQDIPASARPYLDPWVKLAIQESETKAPSYAVPDRDEIKALLADDDSSDGGSVESGAELWALVEKWALSTGKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE21</accession>
    <name>A0AAD8UE21_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360105.1">
        <property type="nucleotide sequence ID" value="XM_060514747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE21"/>
    <dbReference type="GeneID" id="85398645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="34877" checksum="8BC7F6231A51FCDC" modified="2024-05-29" version="1">MNSLTPTKHQQHAPPDKLAANSDAAVWESTILALCRQSSIPLLDKKVQTWRDGFEGAEYRDVHRLVQEHRLPRDATRQIQGWLREAHEMESEAKTCGHKPTWVLYAGLVQDCEAELHCLRNQFVIKTFRFEHIPHNLAKLRRWIGRGEENTAAKTTGATSNTTTTEVKPLGRTVSLSSLRKPRPLSLELVRGAVEFPDEIDGLETMMDDDNEEQEGKETEETEDYADSDRGWTRRQKDWARREEEQESERLQLAMRYKYPVNMRRAKTQYLRAMERQEWEQDKRVFDFAGHGRFSWALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UED5</accession>
    <name>A0AAD8UED5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_734453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360033.1">
        <property type="nucleotide sequence ID" value="XM_060512944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UED5"/>
    <dbReference type="GeneID" id="85396842"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042073705" evidence="2">
        <location>
            <begin position="18"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="553" mass="52021" checksum="F3D1983407163503" modified="2024-05-29" version="1">MKFSTAAIALLAGVVAAAPASEVSRSRQRRAGGSELIQQLQSTFDRNNPNGTPAAAGDPDDLNGDGVINVFEAGAQASKRKRGGGGNGGQQAAGAGAGGNGAQAKGGNAGGNANNQNNAGNAADEEDAAAGNGGAAADEEDAAAGNGNAAAGNGGAAADDEEDAAAGNGNANAGNANAGAGNAKAGKNKNAANGAANNAGNANNAGNAAAGNGAAADEEDAAAGNAGNANNNNNAGNAADEEDAAAGDANAGNANAGNANAGAGNAKAGKNNNAGNANNNNNAGNAADEEDAAAGNAGNAADEEDAAAGNGNAAADEEDAAAGNGAAADEEDAAAGNGNANAGNANAGAGNAKAGKNKNAGNANNNAGNAGNAADEEDAAADNGNAADEEDAAAGNGNAADEEDAAAGGAANNGTANAGAATGGASAGKANKASKAKASRNGRSLNLYAARNIARGRPSRRTAGDDSEQSGGAKGTGKGKGKGKNRSKGKSSSYSFRKGDEGGNRPEKDGRPDRSGDGLRAEESPAMIGRPDGPGSGLGFAELSEFFEIRCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF38</accession>
    <name>A0AAD8UF38_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiamine pyrophosphokinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_782882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362821.1">
        <property type="nucleotide sequence ID" value="XM_060515571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF38"/>
    <dbReference type="GeneID" id="85399469"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="41858" checksum="0F12A7944452154F" modified="2024-05-29" version="1">MPAPETPVHSSLLRLVETYNNFEKTPDYWEFGYFKGDAWQKLGLIRSQDANLLQELKMPLKKYLSFLVSTKVREPNRVQLDSAHLENSETFVNATKEIRQILSPKKDACEGKFGQSLWADKEEMWPLYGTDIKTGFLCGLSPVFGIVTTGVHLNIYKRDGASFRIWVARRSGKKSFAGMYDQCAAGGYQYKLMEPDIQQYGDSHDTSTKACIEREVKEELREGLREDWINKIKGPHAIQYAYIRDARSGSLANTPELGVKIAYDLELNEDPILDKFNTEEVKCIETKSVEQIVQLLLMDQFKPNCALVMVDFLIRLGCLRESVSSDAILSMKRMLNQHPAVEYLPHWKLGQETNMSRGGGGCHAERGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFQ1</accession>
    <name>A0AAD8UFQ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ulp1 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_761067</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360738.1">
        <property type="nucleotide sequence ID" value="XM_060515175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFQ1"/>
    <dbReference type="GeneID" id="85399073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.395.10:FF:000008">
        <property type="entry name" value="Ulp1 protease family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="26446" checksum="97CB8AF685F535F5" modified="2024-05-29" version="1">MPFRKMARHFGDTLSPQQPYLSFTYEDIKSLKNDWLTDNNIAFWEEWLEREVLPKYPQARIILLRPSMTFLLMKEPDMRQIRSALPDFSKVTHIFLPINDARNVAQAEGGSHWSLLLVSAIDGVAFHYDSLGGANYAEGRLATHKMSEILGRPLRYLNLDDSPQQENGSDCGVFVCILMRHLLIKRLLSANAREKVSMSMANKLIDSHGGRKEMLKIIESLRKEGERRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGH7</accession>
    <name>A0AAD8UGH7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_582594</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362743.1">
        <property type="nucleotide sequence ID" value="XM_060505567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGH7"/>
    <dbReference type="GeneID" id="85389466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="513" mass="57685" checksum="FEF12137EF564300" modified="2024-05-29" version="1">MLWLLWAPVALAAVIVAVDRLRKKIKPNYGLPLVGSPNEQSLSSAIIDGYQKYPDTAFVVPSDPPRVMLPMNLYQEVIQAPDSEMSFAAEIYDIFLGRYTHVGESRWEVIEAVRIDLTRNMSGVLRPIQEEAKFGLNQLIGDSGEWKTLNSYHLVLRMIGLMSGRVFVGMPLSREEDWIRASITFATDVGKSRMAALRWNPWIRSFVLPFLPEVRHTRRALQKANEQMRPLVKEVLRSESLPEEKPAKPGAPGAFVSWMMKYLTAKEKTPETMGTNQMLLSFAAIHTTSGTTTLALHDLLGRPEYIEPLREEIVEVIKEDGVEEDENGQVFLSKSSMGKLKKLDSFIKESQRTSPLSFAGTSRRLRKDQTFSNGMKLPAGAAISFPLWAVYNSTTTKTFSPEYNAETGNAPPSEFDGFRFARLRDQPGREMKHQAATTGPDAFNFGHGPHACPGRFFAVYVIKCIFIELLMNYDIHLKGSAGKTTERPPNQINKMIVQPNFGAEVEVRKRTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGI6</accession>
    <name>A0AAD8UGI6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_783543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362507.1">
        <property type="nucleotide sequence ID" value="XM_060515592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGI6"/>
    <dbReference type="GeneID" id="85399490"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="238" mass="27710" checksum="6AA357FD65224EF5" modified="2024-05-29" version="1">MSSDTDPVFDQTAAAPMRKKTFKCPIAGCIFNVDKSIFFEDVRVWDAHVAEHLTCPYFFCREKYPDQTSMKEHETKHDKANDCDFGCSWRMCNNTFKDLKSARMCDWSHLAVQFEADPHWRCRKLKDNGEVCHKGFKKNELPEFEKHLREAHKVPLDDVFVTITESEVMMNGKGFWCRLCGDFGEAWSNDDERLPKYGNEPWAWVFRFLDHVSAHSISTKKMVGDAEDTDEGRETDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHG6</accession>
    <name>A0AAD8UHG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protoglobin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_719939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364422.1">
        <property type="nucleotide sequence ID" value="XM_060512228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHG6"/>
    <dbReference type="GeneID" id="85396126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="2">
        <location>
            <begin position="20"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="295" mass="33073" checksum="2B25F0279C3C635A" modified="2024-05-29" version="1">MGLMRHMNHVDREELYTDLEARIRYLHSFLDFSSKDIEALIHGAKYVKALIPAVVNIVYHKLLQYDITARAFTTRSTSFEGPMDEVPDDNSPQILHRKMFLRAYLAKLCSDPSKMEFWEYLDKVGMMHVGLGRKHPLNVEYIHLGACLSFIQDIMTEAILSHPRMVMQKKIALVKALGKVIWIQNDLMAKWHCKDGAEFQRDGDEDGDGLEIEEEGYLHGKKILESESDEETAVNGVPGGNGPKSPSRLPTRRPNSPGSGGVCPFTGISAGMEGMKVSESKAEKEEGPQRVEASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP5</accession>
    <name>A0AAD8UHP5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Polyketide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_653355</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363092.1">
        <property type="nucleotide sequence ID" value="XM_060510609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85394508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="40"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="1004"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2369"/>
            <end position="2446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="484"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1004"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1159"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1309"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1316"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="1036"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2461" mass="265061" checksum="B0EB832CF6582F2C" modified="2024-05-29" version="1">MTHMRADTFGIGGNLNAGLLREPQMAQNNVVGRVDGADALEPIAIIGMACRFPGSVSTPESFWELLNNARKGHGEVPEDRFNAKAWRHPSHERKGAIQPDSGFFLDEDPAVLDAPFFSITAKEAAGMDPMQRKLLEVAYEGFENAGIPMEKLAGSDTSVYIGVMTNDYELVSQTDIYNLPQNAASGTSRAMLANRISWFFDLHGASLALDTACSSSLYAFHLACQSLRTGESRQALVGGANMILHPNFISQLSAMHMLSPDGISHSFDARANGYARGEAITTIVVKRLEDALADGDTIRAVVRGTGVNQDGHTPGITMPSSDAQAALIRSTYAAAGLSYDNTGYFEAHGTGTPLGDPLELGAVGAIFGPSRRGTRTPLHVGSVKTNIGHTEGSAGLAGVVKAILAVEKGYIPANAGFEKLNPKLRLDEWGLTLPLETMPWPVPGLRRASVNSFGFGGANAHVILDDAHHYLESRNLVGNHQTAVSVDGGTSTSSESGDSGISDVRNHRDGSKQLGSVHGRPKVLALSAHDQAGIKRLSSAYAQFAAESQHREGSFVHDMAYTLAARRTKHPFRSFVVASTVDNLASGVSAAPATLKRSAKNGTLAFVFTGQGAQWATMGRELLDVPAFKESVLRSQAYLDALRCKWNAIELLCDADGSRLDIPEFCQPICTVLQVALVDLLGHWGLTAKGTVGHSSGEIAAAYAAGGISHASAIKIAYFRGLYVEEIQRRLGGRRGTMLAAGLTADEAQSVVEEFSSPEQIATVACINSPSSVTISGDEDAIVKLEAALQKREKFARKLRVKMAYHSAHMEVIADDFLASMGKLELKDQFTAPMFSSVTEEVLASPSQLSAAYWVKNMVSPVLFKGAVEALLTHSALVEGANAARRQRKVPVRWTGFVEIGPAGTLQGPLDQITKAVNSKLSSDLTYTSMLKRNKNAMSTSLEAAGLLWATGHNVDLLKVNEDPDHRGARSLANLPPYPWQHSKRFWHETPESLAVRKQKRPRRDLLGIGLPNQNPFEPRWRTPLRLEEQPWMGGHIITGTILYPAAGMLIMVLEAALEIAENDSSRTKKIRGVELGQISFERGLVVPNDGAVETHLSMRPDEMFPEKYHWTIFSIPSGGTWQKHSSGTVVTIYEDTGPNIEDWQARAESFEDMKMRASRKLDVAAFYDQLKSIGMDYGPLFTNVVDAAILPGEQTGLATVSIPDTKSTMPQGVEFPHHIHPATLDAIFHLIFIALFEGNPMDEASIPVTVETIFIAIDQPSGAGSKYVGFSKARKTNPREACGDIVISDESWSGPKVVMQNMVVRQVSSTDDKSQSSSSPFSQTPKRVGRLEWKEDVDALAGKVASQVLCAYGSQDRFTGLSNPDLAVYLELLTYKEADLRLLVLHAKESHELQSLANIFAPQEERGLRAAEIKFAAPSQEVASQLLSQLAATQYPLPNGSDVIYVPSPEALVDDSSDQLVQELGMFDIVIGDSRQLLGGGGNIGLSHIKSLLHPGGRVALVGDKVSAADYLSGAGFAPVDIDFNNAVVCSTKVQEKLDLSEINLIVRPSPSTAALKVQEVLKRKLEGSGVAVKSCLLSEAATSGSEMCISLLEFDEPWTINLTAQDLDEFRSLVFGAKYLLWLTNGGIADRTEASLAFSPTTGLLRTIRTEVPQIVLPHLDLSITSKLSPEEQSTLAMEVLSLSRKDLYKGKNNEMEFLESGGRLLIHRAVADLPSDHELALRSGQLKSVPGALWAASEPRDLSPLKFDVAGSGVWVADTTQSEPLNDEEIEIQTSHICINGSDLIRSSGQFGTTMATEALGRVVRLGSEVPNLKIGDKVVVLVDESAFKTHIRQHFSLVQKVPEDVKPELAVSLPLSFMTAYHAIVEVGRLAAGETVLIHAVHDAVGLAALQIATQLGAAAVFITANDDETASELIAEYGIPHRYIIRAEDGDVVSKTAMKLTSGRGVDIVISAASGTSLHSATKTVASWGRFVRMGTDGARPQDISAAVFERNASVSSVNVRQLPHERRARLLAMAFGFLRSGLVKEQSLVTSVRAVEDLSDILSSTTVEQGNIVVELGENAVVPVLPRLPAPPQLDAEASYLISGGLGALGLTIAKNMALHGARYLVLLSRSGVVNARQEDAIRDIRDLGCEVDTPNCDVTVRSEVEDAIRTCKTSGRRLRGVIQCAMVLQDSILQNMTIEKWNIATRPKIVGTWNLHSTVPTDLDFFILLSSMSGIIGNSGQANYCAGNTYEDAIALHRRSLGLAATTLNVGLVTDASHFNATSTADDYLRKYGHWESARVTDDEMQAVIEAVVRQGAGGLAEQLLVGITDDVKRDGRAAWPQDRKFEHRIARTGSSAASADTNGANAERLGNELGRAKTLKEAVVVVLGALKANLAAAMTASPDDIDEERPLYSFGVDSLKAVEVRNWIFKELRCDVSVFDILSPSPLAKLGPRIVARSALTPPEIASQALAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI23</accession>
    <name>A0AAD8UI23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_581378</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363272.1">
        <property type="nucleotide sequence ID" value="XM_060505451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI23"/>
    <dbReference type="GeneID" id="85389350"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="816" mass="90902" checksum="2E7A992FB48E7C12" modified="2024-05-29" version="1">MGSIPNNAPTPYDTSPTLPSPHTLSTGAPGPTPAPVGTPVPPAAGGASTSAAAAAAAAAASASRSVKRPRPVKSCTECRKRKLRCDRNLPCSQCQKSHRNCKYAAEHDSSMLSDGSDAEMGEVQRPPKRNCLPTTAASGPQTAESSFVPLRNGESTGHTALEELTSRLDRLEKQFMIRSPAGTEFSGTGQRLPLSPETIRGLTVKRGALRTRFFGQNSVRVLLNLFDEAKDFMANQSKIEGIRETMYGLQILHKRIQEEYRKSLSPISVFADSVIPVQKRMQDILPKKSICDRLLASYIDTSETIYRMIHVPTFKEQHELFWEGKLQGDTFLPQLLTVLSIGSRFETKSKGLGHERVEGVHIPTACALVRSWLDGLKGKQLVDLTTLQTEILLVHAQRMTTPRPQDSWAQLGYIVRMAMTMGMHRDPSEFEPRVPVFFGELRRRLWFTILDMDLHLSLACNLSCLVRDGDFTCRPPRNLDDSDLFFDMKELPPSKPIDQLTDNQMQVYAAMTLGARMQVAHLINRVDSIRDYSEIIEVGTKLDRFLEDINYLFPRHGILNEVEKSKQWRSRVILDMHVRRPLLALYRPFALGLPDAPSQISRAYLRSSMVIMRYLDELDPLLSHFQDVSDMYHMVLKKDILQAAFSVCFYIKAATESHVNGNTFGIASTVAMSPDPMDDGVTFSTETFALWSPSRLIKTVEKTLNLLVRNVGGNDVKDIVALAVVLASVQSTTQEQKLQDIRRSLQGVLDACQTATNTSPEKMSLPKPADPMDPYMQTRPPFMFHANASAAAVSDYGGWVLWDGWDWADAWSADSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIE2</accession>
    <name>A0AAD8UIE2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_577829</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364902.1">
        <property type="nucleotide sequence ID" value="XM_060505059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIE2"/>
    <dbReference type="GeneID" id="85388958"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051701">
        <property type="term" value="P:biological process involved in interaction with host"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000606">
        <property type="entry name" value="C2H2 transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000758">
        <property type="entry name" value="C2H2 transcription factor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="216"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="313"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="393"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="610"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="654"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="694" mass="75319" checksum="6AD4AFA9030F79FC" modified="2024-05-29" version="1">MAAAFRPVNSPLPGADVKMDDKMMTTSPTTPKPSTAPLPRTPQAMAEDVKTPTKATFSSSSSGTAGLASQKPLPSSPFPQAVQVPESAEKVKTPTRANSQHSRRSRDSEDVDMDESDGEGEEGSDDDSVNADGTRSNKKKKSQRFYCTDYPPCNLSFTRSEHLARHIRKHTGERPFQCHCSRRFSRLDNLRQHAQTVHVNEDIPIDSLAATGARFQRQMRTERVRQQGGRARASTAGSAPGPVRGHSKSLSTSSIASVGSIGSAFGPRDDIRRRPPPLVMASDPRSRLSLESYRSAGDGPYGYRPVSPTDYSTPTSATFSTGQSSPRWGSAIASPTTTHSRSHSMYSSGSRTPGRRLSVPSGVNPFQSPHGAPVNRIVYGNGPVNTSNMGAFSPAPSSHLASPTTPTSAWSGRRDSTSSNADEAWRRRTWHPDTRTFNTNTSHLSNVLTPGQIQPNPAPPIVNAPNPQQTLRLPGIESFDPLPSRQVSPPKRIPSPMMVDAEGTHRRPMHPGTEAVADERRNVAQWDMSLHRGLTRLDIASNTTPPRDSAGAWANEVNQAVQAQAEQVRLNPPTVRFEVDPPSYANSGAFTRNHQHTMSAPSFAHRDTKRHGWYHGPMGSNVHGPRPEAPSQDPRGPHVNRMVHPNMGHFAGFPGRQPEPQQAQQQQPGNPDPLRRLEALVAVATSEGTTATAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UII8</accession>
    <name>A0AAD8UII8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Anti-silencing function protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_534017</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with histone H3 and histone H4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361939.1">
        <property type="nucleotide sequence ID" value="XM_060503339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UII8"/>
    <dbReference type="GeneID" id="85387238"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000001">
        <property type="entry name" value="Histone chaperone ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017282">
        <property type="entry name" value="Hist_deposition_Asf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037759">
        <property type="entry name" value="Histone_Asf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="157"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="218"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1720428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="27250" checksum="F58F145AF64C568F" modified="2024-05-29" version="1" fragment="single">MSIVSLLGVQVLNNPAKFTDKYEFEITFECLESLEKDLEWKLTYVGSATSDQYDQELDSLLVGPVPVGVNKFIFEADAPNTSRIPDADILGVTVILLTCAYDGREFVRVGYYVNNEYDSEELNAEPPSKPIIERVKRNVLAEKPRVTRFAIKWDNDAAAPAEFPPEQPEADLVPDEDEYGAEEREEEEAEASAANGEKPAGEDLEMAGVENGEGEAVPAEEDEMSDDGSVDIEGESEDELEEEGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIS0</accession>
    <name>A0AAD8UIS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_420253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362534.1">
        <property type="nucleotide sequence ID" value="XM_060502978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIS0"/>
    <dbReference type="GeneID" id="85386877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="24709" checksum="8DFBDDCFF62CFBE9" modified="2024-05-29" version="1">MEWISQRSHLLKRDLKSLEFSPEEPFKIRTVTLRKPDKHPNVSDFTEEDAFLKWLEKEKSPLELPGLVLVMHPRLDATDPLGARSLPYGESTFKTIAQKLHQHRSLALLFKRASTALVTHKTVGWEGSLTSLPSIVYNCKSDIESPPPKVNNPDDIALSVTSFPTLGTALTIVAIVMNVEISRPSHTFSFMIRAKSTRSNGNDVTPMLAPRNPARELSATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIS1</accession>
    <name>A0AAD8UIS1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_676404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362343.1">
        <property type="nucleotide sequence ID" value="XM_060511159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIS1"/>
    <dbReference type="GeneID" id="85395058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152434" evidence="1">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="154" mass="16675" checksum="5339CD07A38E7748" modified="2024-05-29" version="1">MRFVLLATSLASLAGIVLAKPEKIRGVTDPVYHLYLQAYPKDKSIPVLGPEASAEFFNIAGTIQSANSSSYLNIGGDATSYKTLQLSNASGTSAWGLEGDTIITTQSSSWGRQLNFLVCQLDTSYWQLYLQTGSDVPTGRNCSNYQTIHLPCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJI5</accession>
    <name>A0AAD8UJI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_628217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362748.1">
        <property type="nucleotide sequence ID" value="XM_060508679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJI5"/>
    <dbReference type="GeneID" id="85392578"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="282" mass="31578" checksum="73E372CEE4B6ABF3" modified="2024-05-29" version="1">MEFIVIVHPNQRRSVRLKKQAHAHAARVTHARSRKRQVARHGNQDPDIQVDGRGRSVILRQREGEGVSRPQQDVVESQHLVEPSIPSTIPGAFEHEPLASFLKSSTAEEKMLFFYYGQVIVPNMDSQCPTLCYLGENFDHIRRNWLLCGSTDIDLLQGFLLAASRHLSLFHGEQWGNWAAQFKLKHISDLRRALSSDDMSLRRTGVAKALVLSFDEIMLCDMHMASKHVRGAITIVRDSGGIDALGLSEIVRCVLFSCMFGKGLLDGQPLFELSPAPLSTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK64</accession>
    <name>A0AAD8UK64_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_535317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362045.1">
        <property type="nucleotide sequence ID" value="XM_060503350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK64"/>
    <dbReference type="GeneID" id="85387249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="35805" checksum="F692E54951D7F65D" modified="2024-05-29" version="1" fragment="single">MHLINVHTRLLEEFHADKPKYAILSHTWGPDKEEITFREIKQGDTNKPGIGSVKLEGCLRQAKTDGLDYVWIDTCCIDKTNANELGEAINSMFRWYQEAKTCYTFLQDVPSKDNPKWKSKFRKSRWFTRGWTLQELLAPSELMFYSSDWQALGTKLELSEVVGGITGIPARFLLGASNLREASVAQRMSWASNRETKRVEDIAYSLLGIFNVVMSLIYGEGDGAFIRLQDTIINATTDDSILAWGLRPQIGVVDSRNRPRDLVGGILAPSPAAFAGCGNVTSRENHTPTIEGNILRGYLKLRIRLHSDRSGVTYGLLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK68</accession>
    <name>A0AAD8UK68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_730901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364813.1">
        <property type="nucleotide sequence ID" value="XM_060512856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK68"/>
    <dbReference type="GeneID" id="85396754"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="18139" checksum="120F37445B8F4D32" modified="2024-05-29" version="1">MGVVEKGNKIFVSASEIDKNKVTVEWQQNFKQRSQEYYTVPFINKSQGDQESVLFIQTNYLDAFKKKQVAGEPEFTVIVDTSFQYGQNDEKTSRWLVYHDKSMNAFQRLTPRLQWRFVASVKSKLGNQLGSFGGGIFKSFIGVDIGNLAALIGHPLRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKP3</accession>
    <name>A0AAD8UKP3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">gluconokinase</fullName>
            <ecNumber evidence="3">2.7.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Gluconate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_580334</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363720.1">
        <property type="nucleotide sequence ID" value="XM_060505341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKP3"/>
    <dbReference type="GeneID" id="85389240"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="13">
        <location>
            <begin position="564"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1230" mass="134880" checksum="62EDF808AE599C62" modified="2024-05-29" version="1">MSPPSVYGPTSAALPSSSLDANLIVDTATVQDLDNDDSTLKTVDELVRRRARSNPDQVIVSYPSSGITYVDYTMRQLDVFAYRVAKFYEQRIPSRLNSDEKPTTVAVLGPSNFDYLVTMLALTKLGHTTLFLSTRISQEAIESLISVTGAKFLLADKRYLETAEGAKQTLPHLDVLEIAGQSTFDFPIEVHADTRLDYGRDLSVETNNLIYIIHSSGSTGLPKPIYQTQKSAIHNYSSSMNMKAFITLPLYHNHGICNLYRAIYCGKPIHLYNADLPLTREHLTSIMRKHNFEIFYGVPYALKLLAETDEGMDLLRQLKIVMYGGSACPDDLGDTLVNNGVNLVGHYGATEVGQLMTSFRPPNDKVWNYVREHEKLAPYLKWIPRGPNLFECCVLPGWPAKVATNQEDGSYCTKDLFEPHPTIPKAWKYIARLDDTIALVNGEKFNPVHMEGTIRSNKNITECVIFGVGRPSLGALVVPAAALAGKSNDEILEIVWPVVESASKSVEAYARVSKNMIKLLPYDCEYPRTDKGSVIRQAFYKRYAKDIDEVYDNADAASGDLKKFSVPELQDFIRQGLVQTLSKKVQLDDDTDFFSLGLDSLQAIQMRSDILRTVDIGDNKLGQTVVFDHPSINKLSAYLYSLGTGKGVQADVPIESEMQELIDKYGNFGPIESAPRSSVAVTGATGSLGAHIVAKLAADPTIKTIYCFTRASSDADAARRVKSSLIQRRLYHALPASSRRKLVALSTDLADAKLGLTEDLYRQVKQDLRLVIHAAWSVNFNMRLSSFAKGNIAGVNHLIALCKSAGDVETGASSPAAFNFCSSVSTVARATTIPVPESVPDLEWAQGMGYAQSKVVAEHLCAKATKAGIKSRVLRIGQIVADTQHGVWNATEAIPLMLQTAITVGALPKLQETPSWLPVDTVAQGVIDISLSDADGVFTNVANPKMFSWTDDLLPALKAAGLEFEEVEPKEWIRRLRASNPDPAANPPIKLVDFFASKYDKDEFAPSKTYVTDNACSLSPALAQAPVLDQKLVDNFVRYFKANHWAKKNQGSAKTVIMVAGPCGSGKSTLATSLASSLKAPFIEGDSLHSKASIEKMGGNVALTDEDRSLWLGRIGKRASEALSDLGYDSVVVSCSALRKSYRDTLRSIFAEQEGVKVVFLDLQASPETLVKRMNERKGHYMLASMVEGQVEVYEAAGVAELDVLPVEAEGTSEEVFEEAKWLLEQIGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKZ5</accession>
    <name>A0AAD8UKZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366267.1">
        <property type="nucleotide sequence ID" value="XM_060504746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKZ5"/>
    <dbReference type="GeneID" id="85388645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="317" mass="36606" checksum="16D55D5B0A424E88" modified="2024-05-29" version="1">MPEAVPQTEEEGQYLIHCLIFQSVASSSTSIRNSLLDYRLENGRTYHRYKDGKYNLPNDERELDRLDLQHHLWLLALDDRLGVAPPCREGTKVGRVLDVGTGSGIWALNFADEHPEAEVYGIDLSPTLPGYVPPNCRFEVDDAEEEWTWSRPFSYIHSRVMTSSIGDWKLYLQRCYDNLEPGGWIELQEFDLYPRSDDGTLTHEHSLIKWCDLLLEASEKFGRPYVEVPPLKDLLTEVGFVDVSLDLYKWPTNTWPKDEKYKEIGSWHGENVSSGLEGFTMAALTRALDWSRDEVNVFLIDVRNNIKDRTIHAWWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL48</accession>
    <name>A0AAD8UL48_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_777533</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365368.1">
        <property type="nucleotide sequence ID" value="XM_060515482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL48"/>
    <dbReference type="GeneID" id="85399380"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000012">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="47"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="539" mass="57772" checksum="37D82ED6C92A7F65" modified="2024-05-29" version="1">MSEDHEKVETPDRATTGTPTENPSSESAKQEAEDESQYPHGLKLAVIILSNMIAMFLVALDRTIITTAIPRITDDFKSLGDISWYASAYLITSSATQLLWGRVFTFYSTKVVYLIAIFFFELGSLLCGVAPNSVAFIIGRAIAGAGSAGIYSGSTILITTVTPLSKRAGYVGMMGAVFGIASVIAPLIGGAFTDRVTWRWCFYINLPVGGAAVAALLFLFPSFASKEPTPIKQQIKQLDPFGNLVFLPGVICLILALQWGGEKYPWSEGRIIALLVLAGVLLIIFVGIQIWQQENATVPPRLFKLRNVWLGTIFAFCLGAVLIIFLVALPIWFQGIRGTDAVTSGIDTLPLVLSLVFGAIVSGGVINGIGWFNPVFFSSVIFMAVGGGLISTFVVDTPTRTWIGYQIILGLGIGQGMQLASLGAQVALAQKDVPIGVSLMFFAQSLGGSVLVCVAQAVFNNELRSRLGTFSGLDVDRVIGAGATQLRNFLPPDILGNVLVEYNAALRSYFYVGLAAACFAILPALGVEWKNVKGKEFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULJ5</accession>
    <name>A0AAD8ULJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_623771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364215.1">
        <property type="nucleotide sequence ID" value="XM_060508396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULJ5"/>
    <dbReference type="GeneID" id="85392295"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006969">
        <property type="entry name" value="Stig-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04885">
        <property type="entry name" value="Stig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="17586" checksum="EAD29653F9C985E2" modified="2024-05-29" version="1">MSATQLQSDGKNCGKCGTKCGGSTTCCNSECLPRDTFQSDPMNCGKCGNKCPESFNCHSGHCLEPHTCTTGVSLLESCQEPIVSGSSCGAGEDELCDCMEPVQGDPFCGAFDGQYCQDMCNSDKDCQNSKGKKCARRDKTCCSAVTTDDKIHKTFKGVCFEACAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULJ7</accession>
    <name>A0AAD8ULJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_619249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365623.1">
        <property type="nucleotide sequence ID" value="XM_060508111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULJ7"/>
    <dbReference type="GeneID" id="85392010"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="50"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="693" mass="77882" checksum="287C24EC92532F7D" modified="2024-05-29" version="1">MSSGIAKFEYSHRIGKETIRLVRILGCGATDDGPLQLSLEEHAVADLPAYRGLSYTWGSPLAEKEPSQQIEQQPATVSVMLNGRSFELFPNLHDSLCWIRAHNSCDLYWVDAISINQADDIERSMQVGIMDRIYKKATRVDIWLGSVTEEHHPTEVSRLVHTMAENTQRNFSFDQENSFFDDDALSRYGLLHVPDDVWYAFVAFFERKWFNRVWVVQEVALSKDACILWGNDVIPWETVAYCSDFLYESRLYEQLSEVLYDNNPTIKDVKIGSNSSGIVAIQRCRHDILDLWDSTTLDHIVGPLACTGGSSRTKTAGALLFLMLRLTVGVEATDPRDQVFGLLGILNLLLDLSGRTRTELEANYRRHCTPTSIYTDTAVFIMEECNNLTLLTAVADGSVNKIEGLPSWVPDFSANGPSALLAMRWPAEIPYFDACRSMPTNYRVVDDRLLHVKGLCVGTISLVGEVYSELATNGSFTQWADFLLQCDPVYQPTGQCRVEAFWRTLIGDRDALRHPAPDSLQKAFHSWIADHVVWEVYCAMKKGADIEEHISRLDSIKRLAASDVSKTVPSCDVIMGYLKQLKECEKQEQVEGLFDRFKHTCQVYVNLAFETLWERRPFLTDSSHMGLGGQSAQEGDGIWVVAGCPSPLALRELPVSSISGPFSYRLIGEAYVHGIMHGEAVGEDVSWEDVCIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM15</accession>
    <name>A0AAD8UM15_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mannosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_575507</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365893.1">
        <property type="nucleotide sequence ID" value="XM_060504822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM15"/>
    <dbReference type="GeneID" id="85388721"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF2">
        <property type="entry name" value="ALPHA-1,2-MANNOSYLTRANSFERASE ALG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="599" mass="67646" checksum="31AE157BF0403231" modified="2024-05-29" version="1">MPPKAAPRAREFVHPEAGHARKKPPSAFAIEPISAFYCFLIANIISALFAPIQDCDETFNYYEPTHYLSHGYGLQTWEYSPTYAIRSWLYVGLHAIVGNIRRLMPQSTKAKFFFIRYVLAFSCALCQTLLFRVISLTLNARIGLFFILATVFSPGNFHASTAYLPSSFAMYMAMLGASSFMNWRGGLKTAQGIFWFAVGAVVGWPFAAALCAPFLVEEALFAALSDTDRLIEAIMRVVRGVVAGLIVLFFDGVINTFFYKKIEVAAWNIVKYNIFSETGGPELYGTEPWTFYFRNLTLNFNIWFALALVCLPLFLLQKIVSPSGQGFQTGLRALVFISPFYLWLGIFTLQPHKEERFMYPAYPFLALNAAMSLHIVLTALGNSDPKTLIGKIPAKLKLSLVTITLLLSFDISLSRVYGIWSAYSAPLSLYKPLGAGVSGQQGLGVRGDNVCFGKEWYRFPSSYFLPRDMHAKFVRSEFRGLLPGEFSEARTGFGFWSGTWMPTNGMNDRNQEDMGKYVDQRFCGFMVDTQYPERTAPLPPNEPDYIADAENWEIVKCIPFLDAENTHVLARALYVPNLPFVPEQFKRKWGRHCLLKHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMF7</accession>
    <name>A0AAD8UMF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_651346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365567.1">
        <property type="nucleotide sequence ID" value="XM_060510443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMF7"/>
    <dbReference type="GeneID" id="85394342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF378">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041912669" description="chitinase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="5">
        <location>
            <begin position="34"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="47991" checksum="ADA55D0427F7417E" modified="2024-05-29" version="1">MRLLFTALGGLLIPLQYAAMAFAQETAGKAASDLKCVMYLTGHSQHPNVPSRELVSHITHVELAFMNSDTFNKDVAEWPLFTTVDKVRTQFMPGTKVMVAIGGWSDTKGFDTAARTPESRRKWAQNVADMVLTALIWIGNTLGELQSPDYLGLRPLQGTTAETITNPQTSGNGEDYKVKNSTNEDKKWEIEAYPLLLEEVRRQLPKGKLISAATPGLERDMIAFTKETVPRIVRSLDFVNVMTYDMMNRRDNVTKHHTGMELSRIAVDNYMARGVPAHKINLGFAFYTKWFKTTDCPEGKEVGCPTPLMEDPVTGGDLGQTGGFSWNDGVQEDVKASFERAQKEGKYDKEGGGYYYLDRAEKRFWTYDTPDAILRKFPALVDDKRLGGVFAWGLGEDGPEYNNLKAVNKGLAERRGSFPWGPGPHEADEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW5</accession>
    <name>A0AAD8UMW5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_281456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365807.1">
        <property type="nucleotide sequence ID" value="XM_060502135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW5"/>
    <dbReference type="GeneID" id="85386034"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="9"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="90"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="186" mass="21145" checksum="CB6291E5C8F8F7FF" modified="2024-05-29" version="1">MLTWILQTVKVHIKSRIVTVEGPRGKLVKDLSHLAVNFSQPVKGTINIEIHHGSRKNVATLRTVRTLINNLIVGVTKGFKYKMRYVYAHFPINVNLEKDSETGLWEVEIRNFIGEKLVRKVIMREGVDVEVSKAQKDELVLFGNSLEAVSQSAADIQQICKVRNKDIRKFLDGMYVSEKGNIEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNA8</accession>
    <name>A0AAD8UNA8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_699248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364979.1">
        <property type="nucleotide sequence ID" value="XM_060511406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNA8"/>
    <dbReference type="GeneID" id="85395304"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004104">
        <property type="term" value="F:cholinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000997">
        <property type="entry name" value="Cholinesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00878">
        <property type="entry name" value="CHOLNESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041775424" description="Carboxylic ester hydrolase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="28"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="4">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600997-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="55796" checksum="73AF547A49BA03A7" modified="2024-05-29" version="1">MGISSLTTFLLSSTFFLQALAAPANAGPTVTIASGVVIGTTAQPASATGTANAYMGIPFAKSPPERFSPPQAADAWSSPLSAQAFKPACIQQFAEKGNAQTLQKAYFGNPAGSLTDESEDCLYLNVFTPTGTTSTSKKAVMFWLFPGNLQFGTASLPIYDGSSLAVSQDVVVVTINYRTNIFGFSNSPEIATGSQNSGYLDQRFALQWVQGNIAQFGGDPSRVTIFGESAGGESVKQLLANPPSPLPFSAAIMESQQSLLVGSGSDSYSKVLKNFNCADIKCLRQVSATDIKAYIEAQSLVFPPVNGDGTSINDVRNSISSKKWPKIPVIMGTTLNEARVFLAVEGMNDGASALSSALSQIGITSAITKAAITTSYAAKALNDPFVVADRIITDAIFTCTTSTLASYLALNGYTAYRYRYDPVFASTSIFANPGSYHTSEIPSVFGTYPAYSKWGSATAQQTKLSSYMQGVWGGFAKNPSGGVGWPKIGSALGFELGLLGSGSSSGVTVSATLAADYPCALYAPFTEAAGFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNT3</accession>
    <name>A0AAD8UNT3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mannosyltransferase putative-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_622238</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364746.1">
        <property type="nucleotide sequence ID" value="XM_060508321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNT3"/>
    <dbReference type="GeneID" id="85392220"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="56072" checksum="1A7BEED4C3EC2DB6" modified="2024-05-29" version="1">MVVKVMPSSRMTTAVFFACLLFLFLYSSYVLTPSYHPTSPAKPPPAQTQSHPPQHSEKPKEDGPTTAWQKEAALIRDEAETLIGDPIQPPYKSKFYDLGQRAKKAREWVKFLDNAPKSENIKPTLEKVEGAIASLFPFIQHSPERPDSKTPFSDLRSSIVPGTRGLIIPTGKGTMRYALHLIGSLQSVLYSNMTIQVVYAGDEDLPSADRGKLQSRFKGIEFLDVLSVVDDTTLQLVKGGWAIKAFAALYAPFEEVILSDADSVFVQVPETLFLDPSYEQTGALLFHDRLLWQHSFADRHKWWKSQIHEPSATLNKSLVWTEDYAEEGDSGVVVIDKSRLDVLMGLLHVAWQNTYDVREEVSYKITYGDKETWWFGLELSGATYAFEKHYGSMVGWFKDKVNDSIERICSFVIGHVDVRDDLIWYNGGLLKNKKVDPKEFGLPTHTLVDGTWEKGGDRTQMSCMVGHNVKPLSKDAEWILNSSITLAQELDKEFGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPB1</accession>
    <name>A0AAD8UPB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368157.1">
        <property type="nucleotide sequence ID" value="XM_060504369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPB1"/>
    <dbReference type="GeneID" id="85388268"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="23952" checksum="603367858732FAFE" modified="2024-05-29" version="1">MGALKYVEELQKKKQSDVMRFLLRVRCWELRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRARVRRGGRKKPVAKGATFGKPTNQGVNQLKYQRSLASTAEERVGRRCANLRVLNSYWVNQDSTYKYYEVILVDPQHKAIRQDPRINWIVAPVHKHREARGLTATGKKSRGLNKGHRYNKTQAGRRKTWKRHNTLSLWRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPF9</accession>
    <name>A0AAD8UPF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_741222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364849.1">
        <property type="nucleotide sequence ID" value="XM_060513086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPF9"/>
    <dbReference type="GeneID" id="85396984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF7">
        <property type="entry name" value="REDUCTASE (YAKC), PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="36029" checksum="AA84AC220C239C80" modified="2024-05-29" version="1">MVKTLPIGGIRVPVPGFGAMGITSAMGTRLSAEQAEPVLLKAIELGCTFWDTAVAYDAGLNEKILGDFIRKHNVRDKVFVASKCGFDVFNDRSVTNSRSHIRSYIDGTIERLGFAPDLYYLHRIDPKTPLSESIAALDEIRKEGKTKYIGLSECSAKTLREANSIAKVDAVQAEYSAFETLHEESGLIQTAKELDVAFVAFSPLGHGWLVDNFDYQSPDDFAPDDFRRTVPKFQGESFYKNKAIVDEMKKIAAEKGCSLAQLALAWVAAQGLITIPGTTKPKRLEENWASRDVELSESEVLAIRKLVEANKPEGKRFSAMHEAAVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPI2</accession>
    <name>A0AAD8UPI2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_320342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364864.1">
        <property type="nucleotide sequence ID" value="XM_060502370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPI2"/>
    <dbReference type="GeneID" id="85386269"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="39058" checksum="6D8A7DE25A356127" modified="2024-05-29" version="1">MTSEAVSTTSPVVEDAWKSLVERSINEWNAPSGKMHDFAMGFLQNYTSLDDFLCSPRELPLFWFFQRREAFLSQKTFTKWNRDRLDDYVLLPALNNFVMRSECFFVSHFWTTSDDPDPDGSCLRLHQKELGLQSWSHIWVDWTCLPQYPRSESEEEYFLRGLETMPGIIRNCGFSWFYPGFEPRLWILYEIAEYTLTCDGGIEEFEDNQEFVKHIQEMQETSVRSVLSKYGYRCSDDRDKDYLTSCLEILCYLIRFGIDMGDVRRLMSNVLWFSFTPDIMYQSHLGLVRILRFEGVLEFQGQHYEFTPFPKWAKGKYSANARHLGNIEPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR48</accession>
    <name>A0AAD8UR48_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_616324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366389.1">
        <property type="nucleotide sequence ID" value="XM_060507966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR48"/>
    <dbReference type="GeneID" id="85391865"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="73" mass="8358" checksum="8410E3BAC13641F8" modified="2024-05-29" version="1">MYPRGRSSGQSLNLVRIWYSLLAQLTLEVMLLSPCQMCVWISFGQAQELQPVNSPYLRDMIARRSRQKASPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URA2</accession>
    <name>A0AAD8URA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_693741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368068.1">
        <property type="nucleotide sequence ID" value="XM_060511337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URA2"/>
    <dbReference type="GeneID" id="85395235"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF10">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="106"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="66915" checksum="C4339E6B6FE289D1" modified="2024-05-29" version="1">MTAFSLFHQPSFGEKVQGIKNALHLKALLASMFSFSARFAAAPDAGSSTTSEAYSGPSHEQLHKSAMGFVNEAIEEYDDKPPPLCILQALILCTFYELTRGVRGRAWRMLGNCVRIAYEQRLHLVDSITQARPQPGTSGVAQWSAMEERRRSWWAIWQMDIFASTVHRLPTAIDHSVGMNENHLPVPDVMWFQNMYQPSCPLDTAPLERAKKLSKSGNTSDVAWFIVLNSIMRNAQVLARGNLHSVLSDLSPAPGADSRPLKQYLHGSFRKRQSAEDSQQLPVLIGALKQTVALLPRSLTYQGAQLNFKSTGSSSNSDCAQLPSERRSNASQHAIYLMIQLARFMIYHHFAFNEILLGTIFSETDSPPSFGWTSSSKDEKERLSNSEGLRNCLEASDDIHSIVSRSSETHIQWTNPFLASTVWLAASLQVLRKVFAPSTCNEASEMKIKELRAVCQKYTDFWGTPESLLQNLDSLEERLAQKKAEIAAIEATHMLGCASYQHAGHHTSAFDGISSLQNFGLTMGPELDQSSLFTSVVPGHQGQDVPTPISPRNTSTTQGNWFVDGQHDGAEGTVDELGIPGLNASDEFAGFPEGDPELSFFMSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US66</accession>
    <name>A0AAD8US66_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CRT10-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_253420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366813.1">
        <property type="nucleotide sequence ID" value="XM_060501945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US66"/>
    <dbReference type="GeneID" id="85385844"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014839">
        <property type="entry name" value="Crt10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08728">
        <property type="entry name" value="CRT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="806" mass="90378" checksum="DB83E7225EAB9AE1" modified="2024-05-29" version="1">MAGQQGQYHDRGFREAVLGRCQVQNCVDRFGDGAIEVIRQRERDHVNGIENDTLVQGVPSDQIVTGVEDEDAGSSQPMSLERKIPKTPYFRNNLTALSQRYNLYFAAYENRIFVYRPKGIPKQALPREPNLILATKPDKIARHIGGTLNLRFPHQINHIAVGFLGREEILVSVYDDGSVFAYYIRKIARFIERVASGCREPNPLPTYFLRENVGISAWGIAIHQKSRLIAISSNKREVTVFAFGLSRLPEDMDCHARHLDHCERSVLKRKRNWRICIPLGEGGHNIPNLSLWDDHQGYAEKVVANDIYGTTWILDIWKAGTAPFKISHRANVQGQWAFRNPMGWGVIVLPYESFLPARSVTDLLGMEESDIMNAKNSHAGRWIETQRGLPRIRDHPAEPIAQRMPEPEAFGHHHGAAWFQHQQPGFLAAILNNQQFLGLPAPPPPPPPPPPPAPDDNANNADGGIVPPANAIAPPGAPATQNAVLFTPDHEDDDEDGWSEEEEEIPVAAWDDMSSAFDSEDDEVGGPNGQDANEIVFIEEALSATEENVGSGEGMTQIAPPEMLSSFFKNTPNYDMSEFQSSWLDMVYTPHDGKTYVAPTTVIGRLQYLRRPLVKNRNTKEQDRNALEELGSRCCILRTYEEDIEMRSINPDDGAAVFCKDPISWMYPPHPLLQHSERLNMILHIPELSLVVIGSAMGRAILLTPTRSRYHIQGNGYELKQGFRIDRVLPTLSDEKAGRRPPRGLYGIAAGPVQEGGARGCLLRADDAAMPSPASRRYRLMLHYRDHSILSYEISRDDKNEHVLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UST6</accession>
    <name>A0AAD8UST6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366529.1">
        <property type="nucleotide sequence ID" value="XM_060504704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UST6"/>
    <dbReference type="GeneID" id="85388603"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="69790" checksum="417E8AB7A74F4072" modified="2024-05-29" version="1">MSAIAPIQFPGQPPTDDGRGGFPLQQMPQELILEILRQMDNNNISLVPISNTGRLMRNLSIPIIFRVAQISCAEDAFADHVMRVFRNKLIVRSIQVLSIYTEGPPTSRTPGRFVRIQGPVASCRPSTPTDLMFLIGKLYNLRELRLDFRFKATVSLIRPLSRIMDSPQWDLSLVTALSFPVTTDIGFIVTGFPNLRAFSFEAPLNRPLSSIDGLSDLANILGPQLAYIQICKMRWDASDFQEVQAIFPHTSRLTMGGTMAFGGSPARARWDLQVTTGHLTPMTNLKVLALSDERCQTSSPLDAILPVHYQASTMAKKLLPAIGFHDARSRRYDQAWRVWQNIPNLEETTPTMDISRGSGYTAFKAVVPTPSPSASLMTLPLELIIEIIEFSKLSKSRRGVYFEDRNSLRAMSRVCKLFRVFTISGLFKTVCRTVDEDEIHAQLQAIEGNALILGSIRHLSLCTQGPEWPPTKWRNDYDPSIIPCSRAAAALLVKILRKTTPEEVNLTFKCGNKSMVAFFRAELDKQKACLQSVRVLTYPSSITTSFIPQTFPNLRCLSLEINGSPMHTAGLRLIAPKLKSLTTLELYKAHWRCDDLEEVVTLFPSIKYLLIDGELKSTRVSVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USU5</accession>
    <name>A0AAD8USU5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Developmental regulatory protein wetA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_616024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366544.1">
        <property type="nucleotide sequence ID" value="XM_060507943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USU5"/>
    <dbReference type="GeneID" id="85391842"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31555" checksum="A9947920A0D22AD2" modified="2024-05-29" version="1">METWQGPPKDACSIHVDGTDFRSYISSVNDNRSWACALPLPGIELQQWDASQRDLLAPLHPHNRRLEEHGLDFSRPRVLSMPEYETTIRHDACEQPERLPQIITGIGRHRSDPRLSSETIFDHPAGKYYTTSSNINVDNVSQLSDLSPRPLMEYESNASRSGTNVYPKPPPTRHRYRSRSVAETSKLSPPRDRKYLFVNRTVKDGKLISRGVQASGSWKTIDRRKKAARDDERRVAKATTEAISNLRDHLGKMMGMGLSFSDLMEELGREAQKTQVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9C2</accession>
    <name>A0AAD8X9C2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_191200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357866.1">
        <property type="nucleotide sequence ID" value="XM_060501595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9C2"/>
    <dbReference type="GeneID" id="85385494"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="162" mass="17621" checksum="3B9420CA94E7AC72" modified="2024-05-29" version="1">MIIGFSSSIESRRMRDLTLGFPMPAVAAATAGLGLLFALASVVKRNRLTALASAILTALSFIFVVSALGCIFSLFEKIRKELPRSTDLRLATNLRVFHDISMKYGASTWTLVAACAMLLLSSAVFIFAWLAELRQARQKVSDDSREKARFSLSEGRPSDAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9J9</accession>
    <name>A0AAD8X9J9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_639458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359167.1">
        <property type="nucleotide sequence ID" value="XM_060509427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9J9"/>
    <dbReference type="GeneID" id="85393326"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000201">
        <property type="entry name" value="Salicylate hydroxylase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF172">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="449" mass="49434" checksum="4D1CBD7ED7521015" modified="2024-05-29" version="1">MGSIPAGWRQLDVGVVGGGIGGMSVAIALRRAGHKVTIYERNDFAGEVGASVSCAANGTRWLHEWGVDVEKGDPVVLKSLINRDWKTGEPVSVYSLDDYEKRWGYVYNMFHRQYMHAMLKDTAMQEEGEGIPAKLLVNQKCKNIDLASGKVEFDTGLTATHDLIVGADGIGSVVRGLIGVKPEKRPADSSCLHANVLTEDAVKAGLVDYSQDAALEYWGGQEGKWDKIVLSPCNGGKLLSYYCFFPREKGDYVNQAWGVEDRPVEELLAPYPELDKQVLAHLAIGKDIQPWRLWMHDPYPYVNKDMVCLLGDAGHPMMPHQSQGACMAIEDAAALGILFHPKYFNGDVKDTLEVYNTVRLPRATRVQSAAAKAAYNINERIGFSNNTSTSTYKVADERAKLTIEEMNGYDMYKDIEEVIAQRSGAPFTQKFIKGLPIGLELSPGVIVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA86</accession>
    <name>A0AAD8XA86_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_595497</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000297">
        <property type="protein sequence ID" value="KAK1702942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357204.1">
        <property type="nucleotide sequence ID" value="XM_060506799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA86"/>
    <dbReference type="GeneID" id="85390698"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF10">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="39"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1702942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="57080" checksum="7B59A4B6E9F4CCE2" modified="2024-05-29" version="1">MGSSTDAPQNPPAEVQDGDRQHIDSDMAKKIVRKIDFNIIPLLFITYMFNFMDKTILSSASVFGLRTDTHLKGQNYSWVSSIFYFGYFAWTYPTSLLIARLPVAKYMTANTFFWGAVVALTAACTNYGGLLTVRFLLGVAEATITPAFMFLTSTWYTRDEIPTRTGIWFAGNSVGGLVASFVAFGFGHISSDDKVGPWRWMYIILGVLTFVWAFVLLIWLPDTISKARFLKPEERRYAADRVVVAGTGSTEKTHWKWDQVVECMIDPKTWFIFGLELITQIPNGGTQNFANLVIKSFGFTSLQSTLINIPYSLLSAAIIAGTGWIAGRYRKMNCILIAIVVLPCITGAAIIYSRESVSSGVQLFGYFLLSPGPAAMPLAMSLVSANYRGVTKKMTMSSLLFLAYCAGNIAGPQFFKASEEPHYNTAFRTIMICYSLVVVLALGLRFYLQWMNAKRTREEGYEGSAGGAGAVGGGKVMQTEGTAGDVADMVDRLELRPEDYEDVTDWKTAGFRYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAR9</accession>
    <name>A0AAD8XAR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mov34/MPN/PAD-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_643836</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000232">
        <property type="protein sequence ID" value="KAK1706095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357743.1">
        <property type="nucleotide sequence ID" value="XM_060509697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAR9"/>
    <dbReference type="GeneID" id="85393596"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061578">
        <property type="term" value="F:K63-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070536">
        <property type="term" value="P:protein K63-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08066">
        <property type="entry name" value="MPN_AMSH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000033">
        <property type="entry name" value="AMSH-like protease sst2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044098">
        <property type="entry name" value="STAMBP/STALP-like_MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947">
        <property type="entry name" value="AMSH-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12947:SF13">
        <property type="entry name" value="FI19924P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="376"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="173"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1706095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="554" mass="62958" checksum="05382FA67302F7ED" modified="2024-05-29" version="1">MNGPSSPRPARPMSIKEITLAAEDFDFRTTIPFKYWARSADTLFQEATFALQDRDIRKAYQMLWRHSILVLTHLKTHPDAKLPENKALTKPLFDRQNKEVFGLLEELKPQIDRDYKEWQLMSASKQREDDEFTTRPTSYNEFAARDPTLSGNAKILDAADNQELAVSLAQRDYKRRDAARRATRQAGVSAEEEQERRKGGRWEDWEQFSSPATAASEEEDIRRQIEATRRRLDGTDGGRDEDTFSSSQVSNYQGQVPPPRAPPSYSYNYPSISRPRALEWEASPLEPQRAYTPPPPQPPKPPKEDFTMMRQELDAAPPMRPSKEPLTSYRPPSTANALQGGVPELPAKEEVMPPAAKERLAFKPAAYLENGDPIRPVFLPTQLRDTFLNIASENTRRGLEMCGILCGRPVNNALFISCLLIPEQKCTPDTCETENESSMLDYCINEDLLVVGWIHTHPTQTCFMSSRDLHTQAGYQVMMPESIAIVCSPRHSPSYGIFRLTNPPGLPHILQCTASETFHQHSIDNLYTGAKNPPGHVYHSEKLDFYVKDLRPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB15</accession>
    <name>A0AAD8XB15_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="18">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19 20">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BDZ83DRAFT_634361</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="18"/>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360682.1">
        <property type="nucleotide sequence ID" value="XM_060509091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB15"/>
    <dbReference type="GeneID" id="85392990"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002774">
        <property type="entry name" value="ATP-dependent DNA helicase chl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 25" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="24">
        <location>
            <begin position="13"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="115"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="25">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK1716752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="770" mass="85580" checksum="02122340020B18CC" modified="2024-05-29" version="1" fragment="single">MADKAPGDMIVPDGIDYNHPYTPYDVQTDFMKTAYGVLQQGNGQVGILESPTGTGKSLSLICASLTWLRNQRVEEHEASLKINMDDFKDEPDWIVEQMLRRKRDELARTWEEREKKLEQIRQKEKAIEARSAKRRRFDDGPSRSKPRALEGEEDDEWLLDEPDAAGSANDGDAMSGLSKETKDILSRFGLGSLKAEQEEDKVADGVKIYYTSRTHSQLTQFIHELRRPSFPSSVPQSIVQRQSEDNQPPNEPVKHLPLSSRQKLCINPSVSRLGSLSAINDRCAELQKPKSKDKCPHVLKEENIAETHQFRDTAHATLPDIEDLYHLGKKLSICPYYASRAAIAGAEIVTLPYPLLLQKNARDALGIKLEGNVVIVDEAHNIMDAVANVYASEVKLSELRRARQMLGIYVKKFGKKLKGENRVMVGQVGRVVEGLSEWMDGQSKLKSTQGIVDSKVLLRCKGIDQINLFRLIQYIQESKLAYKIESYVAHVEEEAANAGHVKAPPRSSTPVLHILSSFLISLTNLSSEGRIFYEKLTTNPPDIQLSYLLLSPTHAFSTIATSARAVILAGGTMSPFDDYKDHLFPYLSASKLTTLSCGHVIPPSNLCVWTLAGSRPGPNRDTSSTFEFSFQRRADKAMVSQLGLAILNMCNVVPDGVVVFFPSYGYLDEVVAIWDSRTAGEPESIWQRLQERKQAFKETRGGSSDEVLEAYSQAILGEDTDIKPGAPPKPRGALLLSVVGGKMSEGINFSDRLGRCVIIVGLPYPNINSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB17</accession>
    <name>A0AAD8XB17_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_593273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000211">
        <property type="protein sequence ID" value="KAK1707355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358043.1">
        <property type="nucleotide sequence ID" value="XM_060506614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB17"/>
    <dbReference type="GeneID" id="85390513"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="485"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="495"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1707355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="569" mass="63794" checksum="58DF9145B6E5C918" modified="2024-05-29" version="1">MPCTGLTIPGVTHQVGTDASPSVNSSAGTQDCHSMPTPEAGFPSGSYQLLPGFTIAAEKAEEYLSIYRTRMVPNFPFVPIEPEVTARDLHNQKRFLFWCIMQAIVPQTATVQKAVDDWVRKHAATHIIVHKEKKIELLQGLIVYVAWGDVHLQMGINANTLLQLAIGLVMDMTMYTLAGPVSWMPKTLLNDAWAVLGRGGKQFEAPKPTLEEQRAILGGYFIASSVPAAIRRHSQIQYTPQIARCSKAIREADAIPTDQNLLALVRMQHLGDRIRAVFPSPDREEGEPLPIFREHFSAVLASLRKEICALDSGEPAIKKENPMVWAHYGALMVRLYEPCIGMRGASPSEAMSAMEPFSRTESLWFCLQAIQIAIDALLAIPAEAFAYLPFNTVADIAHTMMSSHRLLLEDSASDWDVMLARQKLDLPDIARRLADRFEEADNVALIVGQKRRIFEDESSRWANYAYRARWIRQWYLNKVVGQPPQEQMATEHHQQQAQQQQQQQQQQQQQAQMVPHEGMMTDPNMSWLGGVAMDQSFWEIMMLDGPGQIPIDASMLLPDQAMLPAMQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBU3</accession>
    <name>A0AAD8XBU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mycophenolic acid synthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_587457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360551.1">
        <property type="nucleotide sequence ID" value="XM_060506045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBU3"/>
    <dbReference type="GeneID" id="85389944"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF4">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42424" checksum="F2365EA8BE7FFC46" modified="2024-05-29" version="1">MTVKESHDIITQLQELEFPYAFSKARKLALLKAGSVPSMSRLFAVTGQNNKRNAGKRSVDTEILLREVQSKARDSDRYAMSVARMNFLHARYRRANKITDPDLLHTLGDGLAEIINVVNRYEWRKLTDVEVCALGIFHKNLGEDMGIPFDLLPSYKDGWMDGLHFAVKLRDWTVQYEEEVCKPVPTNDQYVRVYVDSALSSLPGFLRTALRKSLGADLGDVVRLSLNLESPGILLSTFFALVRNSRKLGLRHLALPRPDSSAVKLVNDTSNPETKLYNFGRKSLQPWYMRPTTWSTWGPGAWLVKAVGGKVPGERGSRYFPQGYDLMTIGPEPQREKGREEMMSDMEVIKARGAVTCPFSQAKANTFATSQSLRTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC32</accession>
    <name>A0AAD8XC32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Necrosis inducing protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_556854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358450.1">
        <property type="nucleotide sequence ID" value="XM_060503527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC32"/>
    <dbReference type="GeneID" id="85387426"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27098" checksum="00CC2595F6606120" modified="2024-05-29" version="1" fragment="single">FLLASIPSVFSATLQARAKDVAVDGKWKNHDEIHSLPAEAASGSKGELQLRFQPFIKVLGGCVPFPAVDAEGYLGAGLKPTGKGNGDCGSSEGQLYVRTGTVKERTGIMYSFYVPKVNKEHRHYWASIVVWVYGADVNTAQPVGISYQTDNGVYNVGSYPATKWSSGASLVGRPTHPLVAYWGKKIVGPLTENMENTLNLPIIDWDMLPEPAQKQLDGAIFEHASVPFIDKNFGDNLNKAFDEGFYADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCW1</accession>
    <name>A0AAD8XCW1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_581593</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363129.1">
        <property type="nucleotide sequence ID" value="XM_060505472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCW1"/>
    <dbReference type="GeneID" id="85389371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF6">
        <property type="entry name" value="PROLINE UTILIZATION TRANS-ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="689" mass="78371" checksum="F5061740F694041A" modified="2024-05-29" version="1">MTRTPRGRSAVACKACHTQKLKCNGGAPCERCQTRGRPCVYPVREKYITVPQSYLRRLERQPAVAQRSGDTISSPESVRTDLNDFAIPLSPKSSQIIKEEELEDCSAEFFVKRLRQLSWTATSDDPNSKQTKESTGTNAESYTYSRLKFDFLQSEVSFRLPPRPYAFHLLQAFDEGFSEYHWFLRKRFRERILLTYSDPQSQSHDRNWLCRVSVVLALAESWNRSRMSSAIHMEIAGKHPTSPAQKGAAVPLTLPPHSQSTSQTLPPPPGSEFFEQGLMLLKMSAEEPVPEDVEALCLIAFYCYSLNRRRTAYSYASQSVALAKLLHLHKPHPLPKASDQRRQVRVMNEHRKRLWWTSYCMDRMISTELGVAAAVACVPEGMQLPSSAGLDAEDLEEFSDPGLLTMQTQLCEIKRNVVRTAAQHVDVDDERRLEIIKPCLDTLQEWRSSLPQQVAFTFEESLPTRLMEAPHGRILASTYMRYHQCFILLLRPLYLQKLSSIVQKRRLNNPPNLTGSDAPLDTDDPMRAVKIQCLQAARNNCKILLGLWNYDKIAKFGYWESLHLFSGLAILALARVSIEEGKDFNPNTEDDVALYTRTRALLREMARVGNPAAKDHDVLLSDVEAMVKRISREEKTTPRQSSVEETDGNVEMETDLSFSDFMFSDGGADQQIWSDKDWESILSTYTQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCZ9</accession>
    <name>A0AAD8XCZ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_58118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360203.1">
        <property type="nucleotide sequence ID" value="XM_060505433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCZ9"/>
    <dbReference type="GeneID" id="85389332"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="154"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="37289" checksum="691910ACB129C3E6" modified="2024-05-29" version="1">MAPIGVAIVGGGIFAKEEHLPAVEASDNLTLKAIFSRSLKSAQDTAKLVTNPASPDLYSDDAGEGKSFKDLLARDDIQALILALPILNQPDYIKQALAAGKHVLAEKPIAADIARAQELIEYYKKVSAEKGVTFAVAENYRFQPRYTTARDEVRKLGKVIGFNVRVFFFVKLGGKYIETAWRKKPDYQGGFLLDGGVHFAAALRLLLGKDAAPASVAAFSDLTREHLPPIDTINAVVKTKQGATGSFAVSVGSTLGAFDFHVAGENGSVTLSSHDLTVKPFDGEATTTHFEQTSGVKEEVKAWAEGLAAGTPNPLQSAEEALADLEFLEKIFTSGEQDGAIQKLNLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD05</accession>
    <name>A0AAD8XD05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_58774</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360218.1">
        <property type="nucleotide sequence ID" value="XM_060506071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD05"/>
    <dbReference type="GeneID" id="85389970"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="103"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="145"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="6">
        <location>
            <begin position="286"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1715075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="38651" checksum="CA2650F4A11106B7" modified="2024-05-29" version="1">MSAEKRPADDELGASQMIVKRQNVGSSTGALARLNASGKSSALVQTTPRTSNLQAPVMELSGHSGEIFAAKFDPTGNFIASGSMDRSILLWRTYGDCENYGILNGHRGAVLDLQWSRDSKIVFSASADMHLASWDLENGTRIRRYIGHEEIVNTVDLSKRGEDMLVSGSDDGSIGLWDPRSKNAADYIQTEFPITAIAMSEAGNEVYTGGIDNDIKVWDLRKKSVVYSMLGHQDTITSLRVSPDSQSLLSYAMDSTVRTWDIRPFAPTDRAIRTFDGASMGLEKNLIKASWDSEGKKVAVGSGDGTATIWSSETGKLMYKLPGHKGTVNCVEFAPGTEPIVLSASSDRNMLLGELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD79</accession>
    <name>A0AAD8XD79_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_681869</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359560.1">
        <property type="nucleotide sequence ID" value="XM_060511216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD79"/>
    <dbReference type="GeneID" id="85395115"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050265">
        <property type="term" value="F:RNA uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="12">
        <location>
            <begin position="243"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="11">
        <location>
            <begin position="890"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="382"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="954"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="954"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="987"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1712944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1102" mass="122520" checksum="0C739C1D95414B04" modified="2024-05-29" version="1">MNDSTRNPGMGQFGGSQANGLEDQLRNMILTNGTPPTGQPQVQDASRTTAHFPGGGTPANGPNDHLHPHGDLPEASAGVNGKPPPSPKVGRKRLNQAQRRQMNAQLSIPIDTRPSPPTEAGRPYTGWPSPSHPHENPRLPSHGRPVKTYHNPDLHHRPPHLAGGMSPRSPRQNGHRHLATSDRYQHDQHTSSQQEHGSPRFPRNNHGQLYSPRGQHHPVRPEELENQASYLESLCNTLVAGAEIERGEIAEKEAFRVKIEQVCQAAVAQYEATQNGLENFPPPSVQLKCFGSLSSGFATKASDMDLGLVSPLSTPQPDESGSAIPRLIEKAFLEIGLGARLLTRTRVPIIKLCQNPPAKLLKDLLEEREKWEKGIVDTDHADAADDDETVDTHTKEMTDETIDDSNNPKTDELSPAGSNLNGPRVPAIYQPENQSLSAYYNVAKRTLRKLGGRDVTLSNCRELVEEDYDLLNKVCEAFLKGIRDVPLRHRLSNYLSLSFKTIPNVPNYRSLAGVYAQMEGERIVMLCEREAENGSIDDTDDATRNLIASWKTLQNQQHFGIEPLTYSKHLQLHLEKLKKLPIAQLLTLEQSQFEAASGYHARTLKILANLRPRSDPKAAAAKQLIIDKYTAGIWPAATRKSVQEFIDTTNGPLSLLTVARRHKSLQLALELEKAVDQHLYDPIIENDVREYISILRGPMRRSNVQDPQYDFVIPVTKQNMETIKRMRDLKDPAKMAINQPRDPYRDKLEFPKNGVGVQCDINFAAHLALHNTLLLRCYSHTDPRVRPLVLFVKHWAKVRGVNTPYRGTLSSYGYVLMMLHYLVNVVQPFVCPNLQALGPPPPPPEGLPPNSPALLDENIICRGRFVGFWRDEAEILRLAQMNQLNGNRDSVGQLLRGFFEYYAQNGSMSTYPGRGYDWGRDVLSIRSPGGLLSKTEKGWTGAKTVIEYRPNANNATAVNSPSTDGHPPGLQGQHLTLKSPIDPPTPTTMTTTSGTITTSTDSSAAASAPAQKNGEVKEVRHRYLFAIEDPFELDHNVARTVTHNGIVAIRDEFRRAWRIIKAAGAGNFGEELLQDVAAVKEEGEKSTYLQLLDEIHGWELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDF6</accession>
    <name>A0AAD8XDF6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_655511</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360668.1">
        <property type="nucleotide sequence ID" value="XM_060510802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDF6"/>
    <dbReference type="GeneID" id="85394701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="14">
        <location>
            <begin position="386"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="106"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1716738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="546" mass="60935" checksum="7A36ABDE6F774B75" modified="2024-05-29" version="1">MNSLVQSARRNPQNALVRASARAAVQNHSRTPAFSRLLSTDISGNAALASSRQLSARPTSLRSQFLPEDVRSISSSMQSRSFHLTARQLQQQQTEKPKATEVGAKPAEDTAKPTEEAKAKDAESEGKEESSEKKEGEKAEGEDGKEGEEKQKEKKEDMPPPPPHGDKTPWEVFRETLTAEFGKSKEWNESTKALSGEIQDFAESERVRKAREAYEKSSGAISSAATSAVKTTAGAIGKGAAWTWDTTAMKGVRKVANVTGDALDKATKPIRETEAYKNVKDVIDDGSSSRYGGWVEKEERRKKREAEALKHGKPEIFEEDPNAGTNVTIHKDAAWKEAWNEFKDSNKFAQGFFSAGKVYRESENPLIETARLVTDKIGGWFAENETAQVIKKFRTMDPSFRTEPFLKELREYILPEVLDAYVKGDIETLKLWLSEAQYSVYEALTKQYLTAGLKSDGKILDIRHVDIVRARMLDPGEIPVFVITCRTQEVHVYRNAKSGELAAGMEDKVQLVTYAIGITRVPEDVSNPETRGWRLIEMQKSGKDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDS5</accession>
    <name>A0AAD8XDS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_633227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361058.1">
        <property type="nucleotide sequence ID" value="XM_060509017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDS5"/>
    <dbReference type="GeneID" id="85392916"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF20">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="67"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="551" mass="60032" checksum="F08E4DBD46E8016A" modified="2024-05-29" version="1">MAQVANQVAGAGELFVNGRIFLHNAEAGLETQPTFAESMFVANGIIENIGTTEDLKARHTSGEVTTHDLEGRTVLPGFIDGHVHLLLLGQSLRKVSLENCTSLEEIRAAIKAYAVANPDVPRIMCKLWMHSMTPDGVDKTMLDDIDPRPIFIDTKDLHSTWCNTAAIKELGIENMPDPSGGKIHRDTEGKATGLLSEAAVLTIVWPHLAQVAPKRDRMDAMKDAVQTYNASGYTGLIEMAMDEPAWDAACSLRAEEPNLPMRIHAYWLIKPSESEEERFKQVDRAIELHNELNKATSPDLRIVGIKIITDGIIDACTAHLSEPYAEVGSPPPFWSAEWLGPVVARADAAGLQIALHAIGDAAIKNAVNALANHATPGRRHRLEHIEMASPEDAKHLGELGLTASIQPVHADPAILRAWPRLIGAHRCERAFAYREFADHGALLALGSDSPTAPWAPLQNAYVATTRRSAREPGYDVVVNEHFKLGVCEAITAGAFGTAKSVFAEDRTGSLQVGKRADFVVAEMDWTPQGLLKGEIKATWFDGRRVWPSPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE77</accession>
    <name>A0AAD8XE77_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_557798</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364569.1">
        <property type="nucleotide sequence ID" value="XM_060503531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE77"/>
    <dbReference type="GeneID" id="85387430"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.40:FF:000003">
        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="25557" checksum="1EE92A9E0A99BFF6" modified="2024-05-29" version="1" fragment="single">MSFTTLRPRTSLLTSLQNLALTPTTTTTSRAFSTSSPLATKTISLQKIPTSAVPPYPHGPRLLYKQSNHGLYGTSRIRHGHNVSPKHHQVTPRTWRPNVHRKRLWSESLGAWVRTRLTTRVLRTIRKEGGIDAYVTKTKAARVKELGPGGWKLRWLVMQTSTFRERYVAEREKLGVEGEMREDQTDLVTVMVDAATPGPLSAVSRGILEKRATQMIMEEFALGEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEG9</accession>
    <name>A0AAD8XEG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_720051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364312.1">
        <property type="nucleotide sequence ID" value="XM_060512240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEG9"/>
    <dbReference type="GeneID" id="85396138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF39">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="84"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="596" mass="64451" checksum="DB8C90BD1F53E20D" modified="2024-05-29" version="1">MARAAAVSRTASSGSFHAGAPIPTLGNIESSRRTTMRRQSTHRYHTFPTPPPKTPREQSSAELFPHSDEDSDASDDDHRQTPLPVKQLALLAFLSLSEQTALNSIGPYLPQMVESFADIPDSQTGLYVGILASAFALAQLSTNLLWGYLSDVVGRKPTMVLGTFMLACCFVGFGFCRTYWQIVVVHVAMGMLNGNAAVVPTVLGEVTDRSNQSRAFTWLPVIYSLGGITGPALGGLLVGTMGKRYPYLAPNLLSAGLLFISVIVVAIWFEETLETLEPDHAAWIPAWVRKAWSWVSREAQPRRGSWATRWPRRGSQAVVSTDDDEEEEDDEDEAGEDQGLLQHASENDAHADDDAKLPGDLATWRQLLNRNTVLVLLTYLVFQLSNISYNSLYPIFADANPPTGRGLPPSKIGISLSLAGVATIVFQAFLFQHLKTRLGNLGTYRIALLGLAVSMALMPWIPYLDDEPLFGIGSGPAWLYTELGVILIIKNICAVGGLSSVMLLITNCAPNHATLGTLNGIAQTLSAAGRSFGPFVSGSLFTLSTRVHPKGEALVWGIFGGIALLGWIGSLAIRNRGLESDDWVGEEDGTDGETEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEH4</accession>
    <name>A0AAD8XEH4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_631076</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361823.1">
        <property type="nucleotide sequence ID" value="XM_060508879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEH4"/>
    <dbReference type="GeneID" id="85392778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051751">
        <property type="term" value="F:alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="315"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1720312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="421" mass="47011" checksum="383177A30B9CB8DF" modified="2024-05-29" version="1">MAGLDAFFRPVPLFGAAAILRVAMLYYGLWQDANSAVKYTDIDYLVFTDAARFTAQGRSPYDRETYRYTPLLAWMLVPTAWQGWFSFGKVVFAVADLLAGFLIVRILERRGVKMGRALKFASIWLLNPMVATISTRGSSEGLLGVLVMALLWAVLERRTTLAGLLLGFGVHFKIYPFIYAPAIVWWMDEEMLDRKGAGPSQTQTFGEAVVKFVNAERVNLAIVSLATFMGLNIAMFSIYGTPFLVHTYFHHVTRIDHRHNFSPYNVLLYLTSAFPSAATIRIESVAFLPQILLSTVLVPFILAKKDLATSMMAQTFAFVTFNKVCTSQYFLWYMVFLPIYLPGSTFLKNPKLGATALSLWVVSQAAWLQQGFNLEFLGVSTFFPGLFASSVGFFLVNCWILGIMVSDGDSTAMETGVKAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGX0</accession>
    <name>A0AAD8XGX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ANTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_573703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366862.1">
        <property type="nucleotide sequence ID" value="XM_060504644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGX0"/>
    <dbReference type="GeneID" id="85388543"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.150:FF:000004">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000025">
        <property type="entry name" value="ENTH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="4">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="276"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="497"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="610"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="520"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="643" mass="70777" checksum="77E2C2BE03E14A87" modified="2024-05-29" version="1">MSSSFEKSVKGATKIKAAPPKTKYIEHILVATHAGEAGVGEVFRALQFRLRDSTWTVVFKSLITVHLMIREGSPDVTLAYLSRHPNTLAISSFTDAQTQGRNIRHYAGYLAARSKAYRETKCDWVRTKESRLEKLSVDKGLLRETEILQSQISALLKCDVLEGEIENEITVTVFRLLVLDVLALFQALNQGMINILGTFFEMSKVDAERAMAIYRTFTKQTDFVVQYLSVARQYEHQTRVEVPKLKHAPVNLGRQLEEYLSDPDFEVNRRQYIAEQQGKKNKVGGVSKPASSAFDSKPAANNPFPSSTFPSTNGLSQPKTETAKGPAPDLIDFFESIEQNQTTMAPNAQQYQQQQQMPMQTGFANNSPFQPQPTGFQQNGFAPQPTGFVPQQTGFASNPYQPQSTNPFGQPQQQQQPPQQPQQQPAAQPLQPSFTGAGFGGFSPQPYQPGTLGSIPQDSVASFPTGNTGMLSPQAGQQITNPFRASMLMAQQTGMSTNTAFSNPASPNVQRQSTNPFARSSPQAQQPFSPAPSNSPFQTQPQPQQQTQQLPTIAPLQPMMTGTNPFAKNFTGPQLQQQRPATSSGAIVPQPTGTTNPFRQGSFVNHQTGMGWQHNQQPMGGGLDNLETTPVFPRPIQQSPWQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGX4</accession>
    <name>A0AAD8XGX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Elongation factor Tu GTP binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_572145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367599.1">
        <property type="nucleotide sequence ID" value="XM_060504473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGX4"/>
    <dbReference type="GeneID" id="85388372"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="184"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="609"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="644" mass="70151" checksum="71DB17C6300CF2C2" modified="2024-05-29" version="1">MTSKNIKSLPHEKRKGEAALSDFAEYVEKQQALRYPSAKSTDTSKITEVPEHQHAELDELFDNLDLAEPTPSARLKDLLLGTDDDTLQKLEAVLQERIAEGHGEAVFELGFENNGESMALSIEQWNAAYTRLKEAAKKIRADCQTLITKNVGGDVEAPSAQAGKDSHCSGKIMIRQTPATVEDVIETRIAVVGNVDAGKSSLLGVLVKGDLDDGRGRARVNLFRHKHEIETGRTSSVGMEILGFDTVGDVVVSDTPGRKLSWEEIGKRSAKVITFTDLAGHEKYLRTTVFGLLSSSPNYCLLMVAANNGLIGMSKEHLGIALALNVPVMVVITKIDICPPQILEQTISQITKILKSPGARKIPIFIKDREECINTATQFISQRICPVFQVSNVTGENLDLVRTFLNILPHHGRYDSEAPFEFHINDTFSVPFVGTVVSGIIKAGVIHAGDNVLIGPDSLGQFTSTSIRSIERKRLGVPAASAGQSASFALKKVRRKDVRKGMVVLPKLEGQPAPKVHREFIAEVLILSHATTIKTKYQAMLHVGPVSQTCAIIDVDRPYIRTGDRATVAFRFVQRPEYLAPGDRLLFREGRTKGLGIVKSVGYDPSKPLYPHGDSVAGEDGAAKAKDEENGEKAANSQEVKVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH90</accession>
    <name>A0AAD8XH90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_626700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363340.1">
        <property type="nucleotide sequence ID" value="XM_060508579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH90"/>
    <dbReference type="GeneID" id="85392478"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="81" mass="9225" checksum="F059B853FE2EEE4D" modified="2024-05-29" version="1">MYTPYGWFKVQGSFICGWPLTLMCLSFVLTGVRVRLSSSAMYFACTLNPKFLDGQCYHGTAGSEFFFGFVFVLRIANVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHM9</accession>
    <name>A0AAD8XHM9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_648654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368439.1">
        <property type="nucleotide sequence ID" value="XM_060510200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHM9"/>
    <dbReference type="GeneID" id="85394099"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000003">
        <property type="entry name" value="3-methyl-2-oxobutanoate hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="36908" checksum="589541FC6BDE41DB" modified="2024-05-29" version="1">MSLHTTRSTCLRSCAFLLRSTRPSTAASLMRPMYPAVTQPLQMRHSSHSPMGTTSANQRKKVTLGSLRSLYKKREPITVMTAHDFPSAHVADHAGMDIILVGDSLAMVALGMEDTSEVVVEEMLLHCRSVARATKSAFTVGDLPMGSYEIAPEQALETAIRFVKEGRVQGVKLEGGKEMAPTIQKITSAGIPVLAHVGLTPQRQNALGGFRVQGKTSDGALRLLEDALAVQEAGAFAMVIEAVPAEVAALVTEKLSVPTIGIGAGNGCSGQVLVQVDMTGNFPPGRFLPKFVKKYGDVWSESLRAIETYRDEVKSRQYPAPEHTYPISKEALDEFTSALEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHV6</accession>
    <name>A0AAD8XHV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_753145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363955.1">
        <property type="nucleotide sequence ID" value="XM_060514312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHV6"/>
    <dbReference type="GeneID" id="85398210"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF17">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="32045" checksum="D3C8CEAE9E226565" modified="2024-05-29" version="1">MAPSLRALLQTLSSLLPHLYPITNDITSTSSSLTTPQTTYEPLSGAPQCPIDGSARNACCHVYPSSRLLLTQFWDDTVHAPGAEEDWTLHGLWPEPCDGSYKAFYGTEPQFTNITDILKHYGQDDLLALMERYWVAAYGTNNNLWAHEYNTHASCINTLSSSCYDTAYNPGIEVVDYFTRTFSLFRQLDTFTALERAGITPSSSKRYALAEVTRTLERLSGGRVVMRCSGPGRDVLHEAWYSYSLMGSLQTGQFVPASDLGSYAEAGNCAKEVRYLLKKCKGNCPNAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHY8</accession>
    <name>A0AAD8XHY8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_769421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367972.1">
        <property type="nucleotide sequence ID" value="XM_060515324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHY8"/>
    <dbReference type="GeneID" id="85399222"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042188592" evidence="1">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="52"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="277" mass="29586" checksum="13942535CFDBBAFA" modified="2024-05-29" version="1">MYINNLLASSALLGLASAGYTTKYLTGSSNNTIQVLVEGDGPSLLVWPSFARDSIDDFHEFSTALADAGYRVLRPQPRGMGESTGPIDTTWAEVGADLVSVIDTFGNGKAVVLGHAAGQRMAKNMAAAYPDKVPSIVLACINTGINTNATIAATANVASNYTYSVEERLAALELGYFAPGHNASLWLTGWFLEAMGSTTGAPTSTTIGSNTTQILDIIAKLDPWRREDQWNYTTGLVGSRSTVVFVEDASHALFPENLQGVVDIMVPWLKTQTSSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI07</accession>
    <name>A0AAD8XI07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_614119</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367151.1">
        <property type="nucleotide sequence ID" value="XM_060507808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI07"/>
    <dbReference type="GeneID" id="85391707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF5">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="10"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="34362" checksum="B8B9317C06D17819" modified="2024-05-29" version="1">MQAFQYVEKGGGLRLQNLPIPQPGPGWVQLQVKAAGLCHSDCHILKGIDGVVQRPITLGHEVSGIITALGPDVKGFKIGDHVTVGLFSYPIKLRDWTMAIGLGFDGGYGEFVLAPVARLVHIPDSLPFSQAAVATDAMATSYHAVVIEAAAKPGMTIGVIGIGGLGMSGLGFGVLKGAKVYGIDITESKFKEAKRLGASGCFKSLEDAQDVEFDAIVDFAGTGATTKQAIERVSEGGKVVVVGLAGSEITIPSYALIGRSVTLIGSFGASEQDLRDVFELLANKSIEPELTEIPFAEIPAGLDALDRGETQGRLWSDPSKAKTNSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIW3</accession>
    <name>A0AAD8XIW3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_620545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365185.1">
        <property type="nucleotide sequence ID" value="XM_060508196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIW3"/>
    <dbReference type="GeneID" id="85392095"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="21553" checksum="853376C4DAE98CDC" modified="2024-05-29" version="1">MPFLVVVTPNIPADKKDEFLGAWPQVKEDIAKQPGVIGVAGGHVINENGTPVTDFKFLQTITFESAADDKAFAESAWIKERGDQFKASPGGEPRVKKFETGPLPGEKPKTFTQFCFIDVADESKHEEAKQAWMDLVAALGQTVHFGGKSVDGGQSTGLGILGWDSDEEAKAAWTKPEAQAALQKYQGFGKSVGVMVKLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIY3</accession>
    <name>A0AAD8XIY3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_615057</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366923.1">
        <property type="nucleotide sequence ID" value="XM_060507878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIY3"/>
    <dbReference type="GeneID" id="85391777"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050705" description="Mannose-P-dolichol utilization defect 1 protein homolog" evidence="10">
        <location>
            <begin position="19"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="321"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37179" checksum="CD51914F1CBBF55E" modified="2024-05-29" version="1">MLTFFFFTSLLCPSHWICRNFLHTAWRHDIPRQSRYRLSQYNYKLVQCSSSPDTIATTMDAVRSALQPVTHNLPAPIRDLGVSIIGEHCYKSLLLDINVEDVDCIKLGLSKGIGLGIVGVSSIVKLPQIRKLTSSQSGEGISVLSYLLETASYLVSLAYNYRNQFPFSTYGETALIMGQNVIITVLVLNYTGRASLAAVFVTALAVALGTLFAGSLVDMQTLGYLQAGAGVLSVASKVPQILAIWSEGGTGQLSAFAVFNYLAGSLSRIFTTLQEVDDKLILYNFIAGFLLNAVLASQMAYYWNAPSKKAKGKQKVPIPAAPSTGSSSATSTPAKKGPSTRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKN3</accession>
    <name>A0AAD8XKN3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_569181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369188.1">
        <property type="nucleotide sequence ID" value="XM_060504160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKN3"/>
    <dbReference type="GeneID" id="85388059"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56314" checksum="1D309010DC692358" modified="2024-05-29" version="1">MFAVPGWSVAAEGLKTETQVKKASNPAKNESKKRKRANKQEKKEKKAPTSGANSVLVNPRVFGEKREDAPAATAEADHDGDDADEAEVETPKPSKKQKKEKKERKSEGGEQTQETPKSDKKEKKQRKEKFNNENEPATAAAAETTPSKTHKTASTDKQDKLTPLQRSMRQKLVSARFRHLNETLYTRPSAQAYQLFEDSPEMFSEYHEGFRRQVEVWPSNPVDGYIRDIKLRARARFPNARGGGRPGGAPSKPDGPQPLPRTDGTCYVADLGCGDARLASTLEPESKKLKLKIMSYDLHSPAKHVTKADIANLPLENDSVDIAIFCLALMGTNWLDFIEEAYRILHWKGELWIAEIKSRFGPVHRKNAVVSHSVGNRKKAAAAAGKKTKEPEETEEDRTALAVEVDGHEDKRGETDVSAFVEALRKRGFVLAGQGEGNKGAVDLSNKMFVKMHFIKGAVPTKGKGLAAAKAAGYVDKEKKQKRFVWETEEDKVDETGILKPCVYKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLN9</accession>
    <name>A0AAD8XLN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_568089</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369765.1">
        <property type="nucleotide sequence ID" value="XM_060504025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLN9"/>
    <dbReference type="GeneID" id="85387924"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04733">
        <property type="entry name" value="OYE_like_2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051799">
        <property type="entry name" value="NADH_flavin_oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43656:SF5">
        <property type="entry name" value="NADH:FLAVIN OXIDOREDUCTASE_NADH OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="5">
        <location>
            <begin position="64"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="49333" checksum="207D47D6C2D90A7C" modified="2024-05-29" version="1">MTPRYPGRQDVDPTPLAQPLSFPFSTAVAPNRLMKGAMSERVCTWDVADPSKRGAPTKEFLNLYRNWGTGRWGVLLTGNVMIDPGHLEAPGNPAISLEHQPVEGDERFETWRRIAAAGKAEGSLLLAQVGHPGRQVVSAVQSDPVSASDVQLVTDFGGMTFAKPHAATLEEIKKLTEGFVHCAEYLEKAGFDGLQLHGAHGYLMAQFLSQTTNKRTDEYGGSLRNRARFITDVADSIRARTGPGFVMGIKINSVEFQESGFTTDEAAELCQLLEEHKFDFVELSGGTYESSGWHHKRESTRAREAFFLDFAEKIVPHVSKTRTYVTGGVRSVGAMVDILQAGLDGVGIGRPACAEPRLPQEIFEHGVKSCVKPLLDEQDFGLGVAMAGSQMLQMGHNEEPMDPSDQKATQGLVKDLTAWKARVAESKGQLYGFARLESAPVFPYGGDAAPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLP1</accession>
    <name>A0AAD8XLP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_647616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369730.1">
        <property type="nucleotide sequence ID" value="XM_060510101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLP1"/>
    <dbReference type="GeneID" id="85394000"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="105" mass="11221" checksum="1E4EB58B1B03CD22" modified="2024-05-29" version="1">MGPRGCVGPGLWLLPEEPGSLCCAPCRSQTRGFTLYGNASASLPQPKPRTQVRSSSNGKVTFMQSGGACNRVSVPPIRPSSRLIGHISLCLRRQPGRGLTMDTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMI5</accession>
    <name>A0AAD8XMI5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucosamine 6-phosphate N-acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_747812</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="2.3.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetyltransferase family. GNA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.4" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370245.1">
        <property type="nucleotide sequence ID" value="XM_060513508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMI5"/>
    <dbReference type="GeneID" id="85397406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000048">
        <property type="entry name" value="Glucosamine 6-phosphate N-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF11">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="19223" checksum="69CFB9363559B440" modified="2024-05-29" version="1">MAEAGLFTDDLVSPTVAAALPEGYIVRALRQSDYNTGFLDCLRVLTTVGEIGEAQFAERYQWLSKSDEYYILVIEDTNTKTVVGTGALIVERKFIHNLGLVGHIEDIAVAKDQQGKKLGLRIIQALDFIAAKVGCYKSILDCSEANEGFYVKCGFRRAGLEMAHYYEGDKSKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNC4</accession>
    <name>A0AAD8XNC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_787933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370513.1">
        <property type="nucleotide sequence ID" value="XM_060515671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNC4"/>
    <dbReference type="GeneID" id="85399569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="34534" checksum="AF89073CE09642BD" modified="2024-05-29" version="1">MASKTTYEPLLVTLTFTPGGFQQTKVLSMAPQTTPFTPPSDLCSPVDIRCLVGKTEDLTGDVECLRDQVVAEITASLPTQCFPESYAAIWRPSGNTFSDVASVAYPGTACISGWTTACETTLTLESAQTYTQTWCCPSSYTCLVPTPGGTPYRDCVSLLSTNTEIWINNIATSGGRESTLWSSWRKISLAGLPSAAGGPLSVKHPVFPLYGRVPSSQASGAAAGAGLSTGAIAGIAVGAVALVLLLLGAGLFVCLRKRKQQRVAAAIAAQNEGNTGNEGYGQKGFGYDAKQELPGHGTEMTEVDAATPPPVELSAYPRAAEVEGNQPAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNG1</accession>
    <name>A0AAD8XNG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_374060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370591.1">
        <property type="nucleotide sequence ID" value="XM_060502665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNG1"/>
    <dbReference type="GeneID" id="85386564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="102" mass="11907" checksum="49633AACCAA54CF0" modified="2024-05-29" version="1">MGGRYCVPAHHLRFCPTGLMSEGHDAMKRYGVWATQHPVRWMQLPPSPRHPQYRLFFDDITRRYQQHCALQRMWRWGVISAKGLAGGGSRWLVVGCRKRTLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNR9</accession>
    <name>A0AAD8XNR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">C2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_600933</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370917.1">
        <property type="nucleotide sequence ID" value="XM_060507066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85390965"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04044">
        <property type="entry name" value="C2A_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04045">
        <property type="entry name" value="C2C_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04040">
        <property type="entry name" value="C2D_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037761">
        <property type="entry name" value="C2A_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037762">
        <property type="entry name" value="C2C_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037756">
        <property type="entry name" value="C2D_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017147">
        <property type="entry name" value="Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037232">
        <property type="entry name" value="Tricalbin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="233"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="434"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="577"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="718"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="1067"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="87"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="873"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1270"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1466"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="903"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="916"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1306"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1335"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1483"/>
            <end position="1495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1730862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1495" mass="164497" checksum="265A864A61411263" modified="2024-05-29" version="1">MASALEKNELKVQGVVEAAQDPESNVSADDAQKKIVEESKKAGITAFTFDPDASPEEKRRQAAAAVPAGFHSQRTKGISVVTDVADSSAPVTDLPPPTKEGVIELPKDKDGNTIKTNDPQSQDEEPYTRTGWAPRFGWPADDLHDAASLLDHSTWLESNIPDKFYGDWYHNAAIIAFACISSWLVAVLGGGLGWVFILMAVCSTYYRTSIRRVRRNFRDDINRELSLKKLETETESLEWINSFMLKFWPIYQPVLAQTIINSVDQVLSGATPAFLDSLKLKTFTLGSKPPRMEHVKTYPKAGDDTVIMDWKFSFTPNDTADMTSKQIKNKINPKVVLEIRVGKAMISKGLDVIVEDMSFSGIMQLKIKLQIPFPHIEKVEMCFLEKPTIDYVCKPLGGETFGFDINFIPGLESFILEQIHGNLAPMMYSPNVFPIEVAKMLAGTPVDQAIGVVAVTLHGAQGLKNPDNFSGSPDPYAALTLNRRQQLARTKHVKDTGSPRWNETHYIIITSFNDSLDIQVFDYNDFRKHKELGVASFALDQVEELAVHENEVLEVIADGKARGQLSCDIRFFPVMEPKKLEDGSLEPPPDSNTGILRFTVEQAKDLDGTKSLVGLLNPYATLHLNGRDVHSTKKLKRTNNPIWDNGSKEMLITDKKNAKLGVTIKDDRDLTGDQVIGKYQIKLEDMLECMGKSQEWFHLSGVATGRVKMMAQWKPVALSGVVGGTGGYVTPVGVMRFHFKNAKDLRNFETLGKSDPYVRVLLSGIEKARTVTHKNTLDPDFDEVLYVPVHSARERLTLEVMDSEKMGKDRSLGLIEVFAGDYISQAENGEYNVHDQKKTFQGGLQLHGKGIAKGVLTYTVSFFPCLNVADPEDEEEEAEAAAAAKAIEDAPRSSEAGKFSSSMEKKTEEKKDGTELEISPPKTPVTPVSPTMPRKSKDESGPPKIRLSPQELLKYESGLLIFKLMEAEMPEHNTHLEVWVDDMAFPSYTSSAAKHKKHAFDEIGDCFIRELDFSRLTLKVREKGDKVEGSDKDKDHTIAKLQGNTLDTLKQCLNNPTTLKLKDKENRPSSVKVSLKYIPVKMQLDPSESINNMGTLRVDVLDAQDLPSADSNGKSDPYCKFELNGEDVYKTKVQKKTLHPAWNEFFEVPVPSRTAAKFKVTVWDYDFADKPDFLGAADINLEQLDPFRPSESRLILDGKSGTVRLRMLFRPSYVTRTRQGTSTFSGTFAAPGRIVTGIAGAPIKVGSTVGHGVGKGASFLKRGLFSRKEDDADGASSSFNDIPTIVENGGSPPGPTPGLGLKRATGFSTSDGSESPDTRPGTSNGSTLGGHARKQSNGAASVHSLNPGSPGSGSASFTVVSATGFPPSTDLYIIINQLTPKPKAIGKTKHHKDATGFFRFNETFKTTCTPDTQFKIEAKGEHTLRSDDDLGEALYFVDETGTGAEKEIKVGSGTVIMKSTFVASASTLDPDSPKSIVRRSFMSKRESRSREGTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP26</accession>
    <name>A0AAD8XP26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellular morphogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747216</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370961.1">
        <property type="nucleotide sequence ID" value="XM_060513399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP26"/>
    <dbReference type="GeneID" id="85397297"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902929">
        <property type="term" value="C:plasma membrane of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042059185" evidence="3">
        <location>
            <begin position="33"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1159"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like second" evidence="5">
        <location>
            <begin position="229"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like third" evidence="6">
        <location>
            <begin position="390"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Rax2-like C-terminal" evidence="4">
        <location>
            <begin position="906"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1232" mass="128300" checksum="86E8505B2EFF4F56" modified="2024-05-29" version="1">MRLALGKRPSARRSKWTNLLAVAALAPSSVAAIQFTPVSDANLDLSQLGRIGVAGDFNGISLYQFEEQNEKPYSTNGSESLLSQLPNGAFASLISTDASIHDMCTFTLDNGTMQGVVIGGNFTSLDGTQSQGIALFNPNTSQITPLAGLSGQVNALLCDQAANTVYVGGNFRGANSTNAIAWYGTDGWTNLPFAGFNGPVSSITKASNGHIVFGGSFTGLGNTSTPSTPDGQVINLSSANITSASSTSTSGFSDPRNIICKTDGADGSGNTWLLRDNSAGFWQASFGFGFQPTKMRLWNTHQDGRGTKTFRFTALPLGGILNMTYVDPTTGQNATCTSECPLSNNSTLKFQDFHFVNLVGMNSFRIDISDYYGSGGGLNGIQLFEDDINSYAINDFNSPACADSDTKSSATTTGPWSTSPSLQSSSQYLTAKLSGTVSASSATVTFLPDLKESGNYSVNLYTPGCLQDGTCSTRAQVNVTGIMSSTGSNKFTTSLYQTNNFDKYDQIYFGYIEASSADGFRPSVTLTPLAGQSIDEMTIVAQRVGFTLINSTGGLNGLFDFDPSSATVNTDFKSSKINQLGSSFSSGSAVTSLTTAGDLVIVGGNFTSSTARNVIGINTASEATMALDGGLNGEVKAMELNGTQLYVGGVFSNTLDNAVTGLNNVGVYDTSANTWTALGAGVNGEVSHVVPMLVNITSDSEAESVVTFTGDFSEINAFGDNSAIQASGFAVWVPSQKNWLQNLNGPVPALNGILTTGILDLPGGGSLYAGSMTSATISANGAVTLAEKFGQFPVKFKSSSTTSSTVSKRDSLSSGNITGVVTGAFYTGNNRNITILCGHFTAVGTNGSSANNLVLIDGSNSNSITGLGSQIEDNSTFIALAVTGDLLFAGGSVRGTVNNNAVRGIISLNLQTATFNSTQPPGISGGNATVTSIEVRPDSGDVYVAGSFESAGALGCPGVCYYDTSLAGWNRPGVNLEGTGHCLIWTSKSQLVAGGNFTLNGTSPTMLAMYSPDRQAWSAYPGEDSLPGPVEVLTAGSSDRKQLWVSGTANNGSIYLMKYDGSKWQSAGTTLLPGTIVNSIQVFSLTSSHDNTDILDSNQALMITGSLNVPGYGSASAAIFNGTTFQPYALTVNSGNTAGSISRIFTENQDFFSDNDGRMALGFIVLIGLGISLALIFLIVIVGMALDRLRKKREGYSPAPTSMYDRGGGMRKIPPHELLESLGKGRPGAPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP41</accession>
    <name>A0AAD8XP41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Up-regulated during septation-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_646389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371005.1">
        <property type="nucleotide sequence ID" value="XM_060509960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP41"/>
    <dbReference type="GeneID" id="85393859"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="381"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="625"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="460"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="691" mass="76134" checksum="D0BB6641F3C98B6B" modified="2024-05-29" version="1">MSYSLADQVLGFSQTSQAPPLSSSSDHKPFVWRMHHPDTRKYQLFPKDRQQRPPNKSLDPEQAFALAMGQNDKTEKPCSSSGSLRLRIKEHNLIRRRKVSIPELGPMTTVQEVPMDSRRPPLHERSVSAPGHHIKQHKSNGSVSSIAAADADRSGCTTPARSPDRHQRSTSESQTPRQPASPKQLAPLVIPTHIGNVPRLARQISHNRMRSGSTGQDSSQYSARADDSPRSLARTPYTPLTASTALTTPLSACPTFMSATTPVSAPIMEERSSTKPWEMNYSQDASTPVQLRSENSASPGTDGTQRPFVHSHRRGQSESGSIMDRGRPRKRSESRNNNGLLPKRSCSTRNKSAERRAFEELPSGFRAGEVPSHIEQDELAALQKQAFGQASRFEVLRKEDVELLSRELRQLDERTEYLRRTYNSLRAGRRNLHSRICQYLRSPRTARFSTDSMLKQEEALAELDTSIDDWVNKLEQAENRRTRVRQKLLEHVAAAATLPTPAATAASESLQLAMGIRPPPPVGVGNISTPPRSPTKNSFSSHTASSSPSPQRVVAQVPSTIVEQPVIEECPVASVDKHVSSFSHRRTGMESIRIYADSDVYALLADVENEITKMSAAANQTEATAALSDDEQKEIHRARSHEALSGLANEKPTNAKDTKDTIPSPRAPSPPAKDSPADDGAIFLTSAVFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPG0</accession>
    <name>A0AAD8XPG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_715129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371307.1">
        <property type="nucleotide sequence ID" value="XM_060511711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPG0"/>
    <dbReference type="GeneID" id="85395609"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF260">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="455" mass="49559" checksum="48596755CCE6FF07" modified="2024-05-29" version="1">MTGLPILDPCISFWQQTTRSYPYLNHNDEAPVPKTARYVIIGSGISGALTAFKLVEGGVTASGIVILEAREAASGASSRNAGHIRPDAFRGFTVYKSLHGEEQALKIIANERTVFLAVDDFAKKHNVPFDFVPTTTFDVCLTQEFADHNVKSFEAYRSAGGDVAHIKFYPAEEAREKTSVPQALCAYEWPAGSSHPAKLAQWLLAQCISKGVQFLTHCPATSVTPSSSGVEQIAWDVKTPRGTVTAPTVIHCTNAFVPHLLPQLSSLVTPERAQAHAFVPPAALTGNKVLQSTISLRRGLRWFYSVNQRRSDGVIILGSASASPKVSQAAYVERQTADDSEYSAEIRDDAVANFQDCLPEEVAPRRGLQHTWTGIIGMTPDLVPFIGRVDGSPGQWVCAGFNGHGMARIFTCASGLAKMILGGTWRDTELPECFEMTSDRLQRLREQQPKQASKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPH9</accession>
    <name>A0AAD8XPH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_646248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371337.1">
        <property type="nucleotide sequence ID" value="XM_060509941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPH9"/>
    <dbReference type="GeneID" id="85393840"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="369" mass="41254" checksum="D8F3E697E5F8C35F" modified="2024-05-29" version="1">MPTRSKPGVNRYLKEPTLLFNSGHICDLVAAIRASTTVNRYSQLGVAVTSKAPQSCMIHLGPTNATSSFRDESLDTNFTLQNGWSKYPLNRNSPPGHGCQSDISQMDSKLGIADPLQRYPMPFPTLVLDQTTPDRVSLPRPNETSQGIWAELSLGRIRRSPTFLIDGGSGRDAKQGHALPRNHSGAHSVHDPGFVRRPMWRQDGCPYEYRLLACPPQNVSFQSEMGVGAPRICSATDTTPPWPPRLTVHREGKFCRESTYLCTDSKQDGMPAITPHHPLWATQPQLRLASLRATWPAKLSFREVHFRTSTFRTRGKAKRRNSEGQEQFCFVSSAEQSVPSLCVGSVNPMQRFMRREPRVAKLQQSLVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPN6</accession>
    <name>A0AAD8XPN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_243779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371305.1">
        <property type="nucleotide sequence ID" value="XM_060501889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPN6"/>
    <dbReference type="GeneID" id="85385788"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="219" mass="25149" checksum="D8C85D0B8A0D0EA8" modified="2024-05-29" version="1">MRCVCVCVCVWKWDGSNAQPATRKSGRAGQGKLGRTGQVCGVHRETKTIAVWIRIQSEASFCSFSVSPLLLEDTKKEWIMDHRRYCDMWVIICDQGKSMHRPTSLVCHDCYVLRGVDNMWIPCVTGWTQLARGRGSAVRVASFSRTTLLAREMDLYLPADTRRVLRMRSRVKSWPGNNGDEHNERLIERSAQGNCTWRVFECVLVPWRSMVAELKRKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPN9</accession>
    <name>A0AAD8XPN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Guanine nucleotide-binding protein alpha-1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_565086</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371430.1">
        <property type="nucleotide sequence ID" value="XM_060503708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPN9"/>
    <dbReference type="SMR" id="A0AAD8XPN9"/>
    <dbReference type="GeneID" id="85387607"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000001">
        <property type="entry name" value="Guanine nucleotide-binding protein G(I) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="353" mass="41010" checksum="D8872E75CA25A149" modified="2024-05-29" version="1">MGCGMSTEDKEGKARNEEIENQLKRDKMMQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIFSNTVQSMRVILEAMESLELPLEDQRMEYHVQTIFMQPAQIEGDVLPPEVGSAIEALWKDRGVQECFKRSREYQLNDSARYYFDNIARIAAPDYMPNDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPVSPMKNYFPDYEGGDDYAAACDYILNRFVSLNQHETKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQJ3</accession>
    <name>A0AAD8XQJ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_163807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371634.1">
        <property type="nucleotide sequence ID" value="XM_060501417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQJ3"/>
    <dbReference type="GeneID" id="85385316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996023" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="23542" checksum="E63E495E7E27B8F1" modified="2024-05-29" version="1">MKAAFVAAALAQGAAAVANPIGPGNGFGPGNGAGWGGFAYGGGFGGFGPGGFGNGVASCASSCFSSHFATATPTPAAFCTDAPQLNDCVKSACTSDAAALSTYTSVSSSVCNAFTSCASTSTFTYSGGWWGSKTGDAAAVTITGCPVDGWWGPGGAWGGMGPGWAYKTDTVTLTRTVNGVATTGPATVAQAVSGSSTLLTTFTGAFAAQATSGSGSGSTNAAAPADANRGVLAAGAALGAFVAAVGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D031</accession>
    <name>A0AAD9D031_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PUA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_568140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369723.1">
        <property type="nucleotide sequence ID" value="XM_060504033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D031"/>
    <dbReference type="GeneID" id="85387932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="44984" checksum="FBF1AC0B8CE5C5DD" modified="2024-05-29" version="1">MTRPCRSPFQMDGTTETYFMRYPGSGDSPSTPAAEPLPTKEQLLELCDSVRTSLRHSKSLGPYADRIQSLLERALKDELNHTQSLDFETLQYARLDKLLADVLDPAHQPLPLPLRFRADMALCESLQKMWRARFRDQYFSLDQVRQRSLSIGGEMRDIHFTASGMDPLESWAVSNSCRDPISELEGNQQFEPGHWWLDLACAHRDGVIGTAVEKPTKGKYGVTALPLLTGREEHIRGNLYRYVREGRLSDMHVSLLTRVGTQIRILRGYRLKSTLAPQAGVRYDGLYTIRQYGNKLDAATDKYRLELLLERVDGQKSLDEVQQVPLPSQLDDWHAFKKVEAEMVRQRKGDDGLLDFKMRKEEERIDREHWRRASEFKASLGQEGCGLGLIMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D221</accession>
    <name>A0AAD9D221_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L10.e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371042.1">
        <property type="nucleotide sequence ID" value="XM_060503751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D221"/>
    <dbReference type="GeneID" id="85387650"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.300:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_uL16_CS_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="25251" checksum="9AC5E4DB4C0DB989" modified="2024-05-29" version="1">MARRPARCYRYCKNKPYPKSRFNRGVPDPKIRIFDLGRKKATVDDFPLCIHMVSNEYEQLSSEALEAARICANKYFVKTAGKESFHLRVRAHPFHVVRINKMLSCAGADRLQTGMRGAWGKPNGTVARVNIGQIIMSIRTRDSNKAVALEALRRSQYKFPGRQKIIISKNWGFTPLRREEYLEKKAAGRVKVDGAYVQFLANHGSLEQNMKRFPDAFASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D285</accession>
    <name>A0AAD9D285_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_564991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371238.1">
        <property type="nucleotide sequence ID" value="XM_060503699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D285"/>
    <dbReference type="GeneID" id="85387598"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DBAG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="41332" checksum="0F929B09A8C41964" modified="2024-05-29" version="1">MCAVGLAGLHNLTGNAKMMSTAREKYGSALRHTGKLIRPPHTPSIDVTMRAVVALAMFEVVKGTHHSTSTVHAHVMGGAALMRSWCPMPSAPFAGFRALLQLCYSMFIPLHVAGMPMPPDFYDWVSYGSQLQLPIDRPSTDLAVLIARFVETSSIIHNHVISDGRPKTASVIQQLLDLDKDLVSWENGLEGDWIYRIVHATHLPPKAVFQYEYHKYHDVWTARIWNYYRWCRILVNQNLLDLTNKNPVSSLSLVSAAARDEFLNVIRHLARDILISAPTHWRHPALDGPAQITVESPGGGGAGSAGLPALLFHLKVAGCAPGVPKDYWEWALGIIQTIWGDMGMLHARSMMEAMRAHEDTVLRTGAAGILADDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2H1</accession>
    <name>A0AAD9D2H1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_747128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370864.1">
        <property type="nucleotide sequence ID" value="XM_060513385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2H1"/>
    <dbReference type="GeneID" id="85397283"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="35918" checksum="71FAAC51E45B63D7" modified="2024-05-29" version="1">MPTGTSKKRPATASNLEHAVAPDRPSIRDNGAAATNTIPATQMAFGMSHIVIYQELMTMRRTLDDISRRQEKSDETNKNSETRLQELQPMPKRLDDLGAELNNHYAAAEEKIRKQEEELRAFADRLFQSDEERAALDRKVAQLVAKQSLQATQDDPDNFRAVVRKRPRAVDIEEPVSAPPKPQQQPKRRVESFPEKSKSRAPKSKPAKPNAPKRIPTQFEIFQRYKQGKMDEYFRTSHRRGNELRKFINDFIQGIEDEGISNSVQENLLKRFSGSVRKLKTRKGSRFIAIGNELRWEDISQVVDDPKLQNDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2I4</accession>
    <name>A0AAD9D2I4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bromodomain associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_646731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370894.1">
        <property type="nucleotide sequence ID" value="XM_060510001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2I4"/>
    <dbReference type="GeneID" id="85393900"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00076">
        <property type="entry name" value="HFD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromodomain associated" evidence="6">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="195"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="29332" checksum="CAEB6DF359C304DB" modified="2024-05-29" version="1">MTPPPVLFHALLRPAVLQILRATGYHAARPVVLDAVTELAARYMFALCQATARHAGDNDPQGDVGPGMVDVRMALQELGAVPPDDVLAEGRGAILGEILDSLDEEGRSEAGAELAAAAAAAAAAAPDGEGDLTMATPTAVAERGREREKIVEDTRGVDEFIKWFSGPRNKAIREAAVGDGELELGDYLNVLKKKHSKTGEDSKYHGTIIGKGNDVGEVQVEGGDLPSIHTWRSKMQGPPPGSAPSATSPRIKEESRPPSSGLSSVGDRLGDDRDSMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4C0</accession>
    <name>A0AAD8U4C0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Modin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000314">
        <property type="protein sequence ID" value="KAK1702312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357118.1">
        <property type="nucleotide sequence ID" value="XM_060515127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4C0"/>
    <dbReference type="GeneID" id="85399025"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="77832" checksum="E2506805E02C916C" modified="2024-05-29" version="1">MSSSDPTSSSGSDSDNNDNQVELIVAVVALVISVLAFIIAIFQALQQYYASATGYSSCTPKVMGDWARFTRRRFKWYEFRFEVEFEVPVIFVAPPTNPRGPLGVHDDKEITYMTGTTDSYKKTYTWDQDEYDKHSKTLRAGMTRQAIHTADNELANWTSLLMAIQRMERESRTWQDKEYFGYNPQWEAQTPCHPTQSSTTVPYTLTVGIQRKKKSWDSMPDNMKKPYATTTISHLVEMAAMLGVHWKEFNRNEDRYRGQGNGFSITGYDVDDLGVVFTFEKTGPTWFHENRVVPNNKVKELCFGYCPTIFRQQNNDNYKYADEPKDIGTLQLGSMSAIAETLVVIGCNTNTIRHFRKSTPDTRHIHLFPIAFEILGMVGAVLQIPGTAFRMLPNPTIWHWDRKSFSLRTFLSDYVHIVGESATTEPMLRSTEESRISVILKEAGKIEDKFEELESRDGPEAILRRTNNTEERIYSNDLVMALHSAISKCDEFLQNQERINLVRNVLRVHLQEILRILNDKEGEYKTVVVATGDHVRSKRDSRHDLVVPGASPILRTREENEEIEKEVSLLQKLDSASSSERHGVLAEIYLLSVRKRVIHVVCKQLRVDKARKERGARSIISDASTEVIAHDQQQQINDVWCMLVFRMVCWLLLHDFHGKDIQVEKSEIFGSRLPVYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6H2</accession>
    <name>A0AAD8U6H2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ribosomal protein L11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_154726</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000192">
        <property type="protein sequence ID" value="KAK1708684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358366.1">
        <property type="nucleotide sequence ID" value="XM_060501351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6H2"/>
    <dbReference type="GeneID" id="85385250"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="7">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1708684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="19188" checksum="17D536B4C6C1856A" modified="2024-05-29" version="1">MPPKFDPNEVKVIHLLATGGEVGASSALAPKIGPLGLSPKKVGEDIAKATGDWKGLRVTVKLTIQNRQAAVSVVPTASSLIIRALKEPPRDRKKEKNIKHNKSVPLEEIIEIARTMRHKSFSKTLEGGVKEILGTANSVGCQVDGKSPKAITDAIDAGEIDSKYQPSSDQLHSANKVTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8W0</accession>
    <name>A0AAD8U8W0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000270">
        <property type="protein sequence ID" value="KAK1704082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357375.1">
        <property type="nucleotide sequence ID" value="XM_060509774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8W0"/>
    <dbReference type="GeneID" id="85393673"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="23222" checksum="848EA8351F088506" modified="2024-05-29" version="1">MSYNDHDLRDKHQVRRRHHSPTYSDLSVGSPEYSPTRDAGAVRVAHKHYESPDRRDRVAVYEEDRYRPRSREYYYEERRPRSRPRSEVYDYDRDHSHHSHRHGHHRHHSHTHSRNKRRHSTSGPNWGQAAVAAASAGIIEAGLARHDRDRTARVMTAAAGAGAIDAVAGKHGEKPSRTWENVVGSTVGGLVVDRMAHGSGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Z6</accession>
    <name>A0AAD8U8Z6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000309">
        <property type="protein sequence ID" value="KAK1702485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357140.1">
        <property type="nucleotide sequence ID" value="XM_060513001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Z6"/>
    <dbReference type="GeneID" id="85396899"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="120" mass="13115" checksum="810339DA0ABBC3F3" modified="2024-05-29" version="1">MNERYKMVAFCRTTTGDWNWSVLDLNHCIVNRDGSLMAQDDGSFFLSAGPCSSDNATKSWANYKCSTQNDDSDERHVDHGIDLNLVVGNDNGTLFCGQQPHKGLTLSQGQAGWSGLGVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA82</accession>
    <name>A0AAD8UA82_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_642777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000206">
        <property type="protein sequence ID" value="KAK1707732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358110.1">
        <property type="nucleotide sequence ID" value="XM_060509637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA82"/>
    <dbReference type="GeneID" id="85393536"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="57" mass="6461" checksum="153A72478D39E3D9" modified="2024-05-29" version="1">MRSCELLQITRTSCLWEGAWLSQTSLRPMATMLYHMIHGVCILRCQIKGSFVVDSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAB7</accession>
    <name>A0AAD8UAB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000297">
        <property type="protein sequence ID" value="KAK1702939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357201.1">
        <property type="nucleotide sequence ID" value="XM_060513000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAB7"/>
    <dbReference type="GeneID" id="85396898"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="58483" checksum="377547DAF191CE22" modified="2024-05-29" version="1">MAESSGKDPEAAEKYACTLPAYFIPNFQREWSSLAARLFNTDALDILLTSNEKKQSLALIAIPITSSSFANKRRAQALHRTVSQAREMGQGKRTPARVTIITALLIYMLEPPLTWWEWAAMHQPLGVLRYVRDCADGLSLYSSEGMLKAALAHSPTVSAQDQSDSLLVVDKPSLKEASAKKTSAKSLEPAQLDSDHLALPALRPWTRSITKFTTPSPPSKKRKAESESPQDKKIVQKKESASPKKVKLAVPKKKVVSSKKKTATPKKKVMAESENKPTPQAKDPKARDAEAARRQQPMDNVLLARYMKSAPMLDRIADYNEESVRCVALTSFLRDLKSSGWEDLEKCTWQLIKDGDYESRAFLAEAIMNDVYQRINNSVEDVPQPAQLTEPARVEDATHQPVQQLTEAKQTAQASLDEQFMDTPTKRRSRSGSKQGKKSTQTKKRTAETKKPTTNTLSEHNTPTKQASRPLRFSPSSRMSDDVFNDTSPVSAASPSAGLQQPNLASPPRFNIRGILVKRLKSKDTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAK0</accession>
    <name>A0AAD8UAK0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_772781</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000282">
        <property type="protein sequence ID" value="KAK1703435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357291.1">
        <property type="nucleotide sequence ID" value="XM_060515393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAK0"/>
    <dbReference type="GeneID" id="85399291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1703435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="25554" checksum="A6E5D385DB594747" modified="2024-05-29" version="1">MTISDSAGCDLRLFYLPRLFHTEEAQKTTLRAAIKHKLEKKPQKGCGSLHWIAKTARLVAEAVVRFDLRDDNKPLQDIIIFHEPNASDLHSSAAPSLEIMFNEASLSPTNEAPPHMQDRHRVHKWSRKHTLLELGIVLLQLGTHRDDVEDLPAPPIGPEAKQSYIRSHAEKAVNGVSEGFAGAVRNCAILFDHDDAAKEDEFLGRFLKMVLQPLRDCEKTLCTQGVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAP5</accession>
    <name>A0AAD8UAP5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_595136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000274">
        <property type="protein sequence ID" value="KAK1703786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357351.1">
        <property type="nucleotide sequence ID" value="XM_060506769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAP5"/>
    <dbReference type="GeneID" id="85390668"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021709">
        <property type="entry name" value="DUF3292"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694">
        <property type="entry name" value="CONSERVED EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38694:SF1">
        <property type="entry name" value="PEROXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11696">
        <property type="entry name" value="DUF3292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1703786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="68307" checksum="0C8B0E42B14835D0" modified="2024-05-29" version="1">MGQEPEIVEAHEEERPTDSHHLADMAAKEKPIEEKGHAELDHDHVEVKNLGWNNPPSKVAQPMVGGLSNEDLWILVRRFDKQIFHVKSIPEPPLANLDMNIADEEEFSPDKLRAHVERLYMTVVVGLFSFWKHIVRLRSWREYKRTSLFLAVYSIAWIFDYVVPVFASFLIVLILVPQSRDFCFPPAPASLIDSKTGGVKKPASGVLASDDSITGAPEKHAGEAVEQEASSFVNSISSLIISTAAGKHPQGDPHDDSSVPDPTNITQDVVNAKDKTDGKEPTSHHDKTKKPVHESVWVKARPVMHGIADFVDTWERFGNALSPTPPFPQQRPRLVLASVILPLLLVSLFTTSYMLVKGTGFVVGFTIFGDPIIQRGLVFINRTYPQWQKYVELRNTILKGIPTNAQVTITLLRIGERNKAPLPPPPKSDIDEAIQPDEAALAPAESETAEHKQKKGHRIMNFIKSSAKGGINTTLAADKVKAKVGAKHAKDRLGVVKKTPDPEKGPVRFPARWKGKRGHAYITTTATTPALSWTTESDDLSPTWTVTIGDIEQIRKVGGLGWKSKIFVGWATDREIADGLIVTDSMGKEYHLTAIISRDELFNRLVALGSQMWAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBF2</accession>
    <name>A0AAD8UBF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_640990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1710014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358710.1">
        <property type="nucleotide sequence ID" value="XM_060509526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBF2"/>
    <dbReference type="GeneID" id="85393425"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF250">
        <property type="entry name" value="MFS-TYPE TRANSPORTER AFUA_1G00970"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1710014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="28923" checksum="4D6EE8FB5DD5611A" modified="2024-05-29" version="1" fragment="single">MIHAFQVLLCIGSIGQVFALFMTSLCKLYYQAFLAQGVLLGVSMSLIFCPPVAVVSRRMPHRRGLALGLTIGGSSIGGIIWPIMLEQLLNKRQLGFSWTMRVVALTMVPLLAITCITVVDAPTPKASLSPLQAVLDKNEKGAVSSNDEIQSQTESGYSILKNTTFILLCGGLALGYFGLFTPLFFITGFGAQYGLSTSTAFYLLSGLNGASFLGRVVPGLLADRYGHFNLCALATLAAGIVGFSWTAATSLPGLVVWSLAYGFSSGVSRFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBF5</accession>
    <name>A0AAD8UBF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alb1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_633475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360946.1">
        <property type="nucleotide sequence ID" value="XM_060509039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBF5"/>
    <dbReference type="GeneID" id="85392938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053278">
        <property type="entry name" value="Pre-60S_factor_ECM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022784">
        <property type="entry name" value="Ribosome_bgen_Alb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28280:SF1">
        <property type="entry name" value="SHUTTLING PRE-60S FACTOR ECM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09135">
        <property type="entry name" value="Alb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1717459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="189" mass="20627" checksum="F01B13C16BB75716" modified="2024-05-29" version="1">MAKPGASKKNRQPSLHSRAARRATDVDIDTDKSLKEVKAPAAATDFRPSVLNAQHNSGVSKKTKNRKAQMSAKAKERKEKAADRAEAIMGRTSTKTEKSKDRARRVQTRSKQWEDINKGAIAAKRFPDEEDSEAEQRQTKSRTVEVAAGKGWETDEEMDGADDDVAAPAPAAAVSAPPPANDDFDEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBH5</accession>
    <name>A0AAD8UBH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359713.1">
        <property type="nucleotide sequence ID" value="XM_060510864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBH5"/>
    <dbReference type="GeneID" id="85394763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="28134" checksum="B6090EA7189F3E97" modified="2024-05-29" version="1">MTEWVGQSPGLGAANAGSGSCHAIDVGAGKSLRQSRSRETWDNAPVQQSRRSHPREPPGTPNFSLWPVDVPISARRSFALFRGPPKAADFQVSVGVHDVLSRLAGAEIQREQTHAVASRFTLLAELAKDCEFVESGKREGQDLKLAWLALAHYIGEDGWGGHGRMGVDKKLQQMNTPRRGFTYLAELAKSWEFGKIVRQPDRKIRACQPLTARRADALVQETCPTPPDDAGLSSAVPRAPSAEPDSALRQSQPDAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC40</accession>
    <name>A0AAD8UC40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_63496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360088.1">
        <property type="nucleotide sequence ID" value="XM_060509136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC40"/>
    <dbReference type="GeneID" id="85393035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="13886" checksum="F4C94B49A48F60B0" modified="2024-05-29" version="1">MGEWKLGCITLILPGRKDRDQPVGSADGFPYRPTLAPIHHHRSRQGMPNQFAMYLAPGQTVPTTLYPASFGETWAFFGPTGPPLGHIIEIHAISASGNLGKPLETMFCDPKRGFTLGYSRRRQHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCA9</accession>
    <name>A0AAD8UCA9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1715998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360392.1">
        <property type="nucleotide sequence ID" value="XM_060514709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCA9"/>
    <dbReference type="GeneID" id="85398607"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596:SF3">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="348"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="952" mass="104964" checksum="230D863AC7EC0C0C" modified="2024-05-29" version="1">MEHLPIPRDPIGEHPTIALGTKQFHEPGPFLDYPTQHGEVLNAQYPHVATQADALQGRFTAGISHMQVIDYYQGWLFSSLLQEFLGDLYKWQKYTSWTYGDQQKLETISLSTKTLHEDLASLRASGPLASIRSDDAYDKHLKKCLDQAFEAFDEIEFRFPGFSAAFAKEILCLASLAETLDSAVQTALVHGPVAEIDRGVQHFPESAKRPWFSKVASLLHLSSGDNKLAMIKAGWCPGDITKIGESFNTIAAFYYFSKFKADSTVADLHKDCPEYGCGLRIPAEPKHISKGCNCPGMVSFDEENLIDIYQKGDVPCFSIGRLEDGSLGIALSSCSIDEESQKDPDNHYIALSHVWSEGMGNPTANALPFCQLAYVQHWAMMAYQVVEEKEADESKDGTGIMIQTKPKIRQLNIWIDTMCCPATPGYGKNLCLSMMREIYSNANVVMVRSAVLEALKIGDIVRDPSKGVMDVAAQLYLSPYMRRMWTLQEAVLAGASRARGIGDRLCLSFADGILSLESIINLLKQAPQQEALLAYRFMAEFRDLSTHMWQLGDDHGDKPMKHSLKGFDFFLNMLTVALKYRNVTVASDEMICLATLLNLRINSTRGVVPLIGHGQTPEEGMCELWRRLQALGGSLPSDLIFSSVPRVQVPGYRWAPATLVQYAKHGNLYVSHSSAYPAKISDKGLHVRLPGARLRSLATTAGSFGRLLPKVFVNDGKHIHSGDETAPPSVFLAKLQADEDKNGWFAVRIHKGENDTQKSGSAPAESRSESSQRPSLLQLLGSGSAALIYQNASISGPGLLVSIASQPSDPSALDILSLAQEPLQTTSEFPVRIMPLGSGTNIIAEAANNCVEELNRRVVAELRQRAGGDTVENVWEDANVIAELFKQTAERTVEESSAALKEALYFEVLSTKASATSEAAIERFMQYVRQVAYFGGGIRCESYPEDQDWYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCJ0</accession>
    <name>A0AAD8UCJ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_632117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361486.1">
        <property type="nucleotide sequence ID" value="XM_060508945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCJ0"/>
    <dbReference type="GeneID" id="85392844"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="38598" checksum="37B420CB7CBD2DC3" modified="2024-05-29" version="1">MESGYLDQAEHAGGDCELDVAVFAKLPTGCSVLKVAPSGHSLWVATVQIVVQLEDGTIKKYFKKGARGAIGMDMMRGTFEAEQALYTFSPGQVPKPIGWGTYTIDPGTHFYLSQFVEMREDLPSAQDWAASVRELHVNSMGKCLTRKFGFHVNTYLANVPVNNSWNSSWESFWRQQMKGLFDQDDRVYGMDNELTALKMIFLYEVIPRYLSPLEREGRSVIPCLIHSDLWPGNIKPKKSSSGLCMFDACAYWGHNEADLGICLNPRYKLGQPCIHEYLKRIPAAEPTADFDGRIAVYAMKYHALLSIMYCFKDKSFRQTLKNELKEIIGKAAQSMPEGEGDASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDE5</accession>
    <name>A0AAD8UDE5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide hydrolase</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_630202</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362142.1">
        <property type="nucleotide sequence ID" value="XM_060508809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDE5"/>
    <dbReference type="GeneID" id="85392708"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041767606" description="Peptide hydrolase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="131"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="9">
        <location>
            <begin position="254"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1721346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="496" mass="52505" checksum="D01B518A793FDF53" modified="2024-05-29" version="1">MKFLATTTTIFSTWAALGVSAAVQKRQTTKPLVDSASFQEEITKENLQANLVQLSDIATANGGNRAFGLPGYAASVDYVFNRISSAAGAKVWKQDFSATYSTELRANLTINGEKLTIYGLYGSPDTPAEGITAQLVAGPEGTAACEAASYANLDVSGKIVIVTESVCPGYRDGFHAGVMKPAAAAGASAVIVVNDISLNLTAGNLGPADDGTYVPTGFVNKHIGNPLQARLATGEVLNAFFWEAEVVDSRVTQNVFAETEGGDENNVVVLGAHLDSVAWGPGINDNGSGTSLLLELFLALTKYTTNNKIRFAWWGAEEKGLVGSRYYVNNLAAQERDNILAYLNFDMVSKGYYGVFDGDGASYGVPAPPGSDVIQELFTADFVAKGINVTAARFTNGSDYASFWQILGKPIGGLHTGTGSAQDPCYHQPCDDINNPDLDQLTVNAKTTAHVLSALALDGTNLVKKLSVRVLPARVAVAERVIATVEESEEDEHHPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDR1</accession>
    <name>A0AAD8UDR1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_433291</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362337.1">
        <property type="nucleotide sequence ID" value="XM_060503064.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85386963"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06627">
        <property type="entry name" value="STKc_Cdc7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000176">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000246">
        <property type="entry name" value="Putative Serine-threonine kinase SepH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361:SF433">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="58"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="345"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="475"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="583"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1242"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1242"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1257"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1323"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1349"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1385"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1433" mass="158626" checksum="9B79D83BF83051E6" modified="2024-05-29" version="1">MPNPSPPSSASSSVERQYHVNGRAAVAASRERSSGTPRKEKQGLRESSALQDPGLKDYRLGECLGKGAFGSVYKAFNWGTGEAVAVKQIKLADLPKSELRMIESEIDLLKNLHHDNIVKYIGFVKSADCLNIILEYCENGSLHSICKSYGKFPENLVGVYTTQVLQGLQYLHDQGVIHRDIKGANILTTKDGKVKLADFGVSTSTLAGGQDKEAQVVGTPYWMAPEIIQLSGASPASDIWSVGCTVIELLQGRPPYHNLAAMPALFAIVNDDHPPLPEGISPASRDFLMQCFQKDPNLRVTARKLLRHAWIIGCRRSDAPVSKAPANFSQAVEEVKQWNKALKSSESSLRASTGSDSGVPGMQGHPGSRYSANEPLRPSLITQPKGPLALAKPRRTPEAFRSPELADDDNWDNDFATAISPSALHLPHLKPQDNFGGLLSADKLKAFASLTDARNDSESYDDDFEGELLTIKGPGQFTDFEFQEQTIRPTPRKKSDKYPEPMKQQSPPKPSPRKAGHARNPSRPKSPVKPQLGPSKFEIPAPPDLAFREQNTEDYSDLFMENDFNDGGLNPFIKKVDSPQLFHPSDLTSLPRSTQSPVPGSSRRPPSAKLRPSVLPDRPMRRTRSSIEIQKFAEDEGDEDFSDIFGPEDAVTEREESDRGSEDGGLMVLSKYSNNSWLGDDEDEDDPFASMDPGWDEMDLEANIARDRHARLAGKVEELVRSLKTSEGEEKLCELSEDLLALLWENTEIKDLILSAHGLLPILELLEPCTVKSRQQMILSLLKVVNTIILDDVEIQENLCFVGGIPIITKFSARQYSNEIRLEAAAFVRQMYQTSTLTLQMFVSAGGLNVLVEFLDEDFDDARDLVLIGVNGIWNVFELQGPTPKNDFCRIFSRSKILYPLALVLHRVLDEEGEDELSELIEGRIVNIFYLFSQAENYVKEVVADRQVLKSVLKDLRRMTPNHQITMLKFIKNLSMLSTTIETLHTADAIEFLIDVLGYSMKRGHQHFREISNQVLNTLFNLCRLSKERQEDAAVGGIIPLLMKIMNTDRPPKEFALPILCDMAHSGSKGRRYLWQNKGLDFYVSLLADQYWQVTALDAIFIWLQEETAKVESHLLDGKFTDAIVACFHTNKLNSFDANLLEPLLKLLRLSPSISGSLAKPEMFAGIGQRLGHKKAVVRLNLLRLVRNIMDACEPEMLGMGNGSSSLNVKQVRSLFDTIQMLADKDTAVLVRNLASELVKSHNESELYDMPSERKGSSGSVASRRSGSGPRRKSSYTPPGLHHAMSMPATPTQSQSRHHRLSQIPPGSGGAYIEVAASPRRTAVQEREAILYRPRSREGATSIPRRVSGEMSSSMPNGPSSGKSRLPRHSFARPSSASGQPPLIRSESSLSNKENLSRNTSAVSAPAASPVLPTSMANKRRSRAPSSDVKWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE71</accession>
    <name>A0AAD8UE71_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_723285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359916.1">
        <property type="nucleotide sequence ID" value="XM_060512549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE71"/>
    <dbReference type="GeneID" id="85396447"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="253"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="54889" checksum="96C5565158A23C43" modified="2024-05-29" version="1">MDRFCLLPPELRAAVVECVVADCRYGDESDSLADYALVCKEWQAIVERFNFSVLKVTLANLDDFESSMVGSRRRLVQRINLHVDLPAYDNDPCEKKETWEDKAENNSCFTLAFYRLFGIMNSWKPEDSTSDGIDFSLSISSPSDLRNANFELWQRRRWNIKDIGEKRFADSWIDFVGQDEEFDRVNRLPVVKVIRSFTVSPQNHRALMPAAHADIIARLPGLRTANFDITKDRKKETRKIHFNQFAGSMTKWPTSLESLTIMSNTISSWRQIPHETLAEGDSGAKLCDKLRRAAQHLKELNVTNVVRIREFLRPHWPMGTEDTEPFLANRSYYPEFWLLKTLYISYGSIWYNTEWHKQSDDINESSELVDFRQNVSLAAARMAYTMPQLKHMTIKQRPLMWAGKHELEYKIEGGDKAYLTWTSTFDFKPWERTVEAWVEVAARHERKLEVRIITRAWHTDGKAPLLPSLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFM8</accession>
    <name>A0AAD8UFM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Family 31 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_793640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363387.1">
        <property type="nucleotide sequence ID" value="XM_060515784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFM8"/>
    <dbReference type="GeneID" id="85399682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06591">
        <property type="entry name" value="GH31_xylosidase_XylS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051816">
        <property type="entry name" value="Glycosyl_Hydrolase_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43863:SF2">
        <property type="entry name" value="MALTASE-GLUCOAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="3">
        <location>
            <begin position="232"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="4">
        <location>
            <begin position="577"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="665" mass="76620" checksum="D3576F4A5DDD05DB" modified="2024-05-29" version="1">MGLLEQDGKLVYTYDAEKVWVEPWGLDSFRVRATKAREMPIEDWALLKPKKADVKITIDDKAGTITNGKIKASVTSGGKLMIWNSKGELLLEEYSRHRRDVLDPKCSALDVEAREFLAIVNSNDYHLTARFESVDAEEKIFGMGQYQQPFLDLKGHDLELAHRNSQASVPFAVSSLGYGLLWNNPSVGRAILGRNIMSFEAKSTRALDYWIVAGDSPAEIVEAYADATGKVPMMPEYGLGFWQCKLRYQTQEELLEVAREYRKRELPIDLIVIDFFHWPLQGEWKFDPTYWPDPDAMIKELQELKIELMVSIWPTVDHKSENWDEMVEKGYLIQSDRGIRIAMNFQGDTTHFDATNPGARDYVWKKAKKNYYDKGIRVFWLDEAEPEYTVYDFDTYRYHLGSNVSIGNIYPVEYAKAFYEGMEAEGQKNIVNLIRCAWAGSQKYGALVWSGDIASSWGSLRNQVAAGLHMGLSGLPWWTTDIGGFHGGDPRDEKFRELFVRWFQWGAFCPVFRLHGCREPEQPQHGTTGGAECHSGAPNEVWSYGPEVYEICKKYMFLREELRDYTRSLMKEAHEKGTPVMRTLFYEFPKDQETWKIGQQYMFGSKYLVCPVLEAEKRNIKVYLPQLEAGGKWKPLLEGKSDTYEGGKWIEIDAPLEWMPVFKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFV9</accession>
    <name>A0AAD8UFV9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MINDY deubiquitinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_37479</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360771.1">
        <property type="nucleotide sequence ID" value="XM_060502671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFV9"/>
    <dbReference type="GeneID" id="85386570"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="352"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="923" mass="100196" checksum="A7395D639FAC485D" modified="2024-05-29" version="1">MVTRKPVPNETSLDTNAAAPRVEDMRKELWSATDSPSDVDSVWDDAPQQRGAAALNQQTIPQDIPESLKPGGVTAQAPEMTNGGWNDVDGHPPQTAGETRSESNEIPLVLRPGAPPSRSDTNPFKRKEVRDDSNPTSPPTIGTPTMPPAQPLSQMSTGEISNNPWQPALDQHAQRAAAASAQQSLRTQNSGESERDAWAATQEPKLPAISTSPALLSLPSEPTSPAWDDLPENQSKKPLELPVASIPNDAAADQDAWNDEGGQNKGKGKAPAPAPVVLPPPTVEDGPMDDWNLIDVEPPAGPPPGRSQLPDQSRDRPDQVSDDKVAPALPPRNDDEEQPPRQPPRPVDGKAETYQIKNVRWHDHSTDKNPRVSPILVQNANGPCPLLALVNALTLTTPSSLSETALIEVLRSREQISLGYLLDAVVDELMRRTQEALPDVSQLYTFLKGLHTGMNVNPRFVPTPEIIKAFKRTSLTHLHPTERDDLIPGTFEDTREMALYAAFAIPLIHGWLPTKNDPAYPAFERQAASFEDVQTLLFRDEELQEKLGELTEEEERIYSDIQSIKAFLETSATQLTPSGLEVITKAMKPGSFAILFRNDHFSTLYRHPATQQLLVLVTDAGYATHDEIVWESLADVNGERTEYYSGDFRIVGGEQPQGNSMGQPTSRNNAQNLPRIDTSSANEGGWTTVPGRGNKHLEAPAQGDEMPLSPNHEQEDRDLALALQLQEEEEQRHRAEQSARRRESQLSEQYIEQQARLQQGPTTRRAADRQAARTGTSARSNSNGNSTASRGSRRNSSTNVSGAAVPPTSGRQPGQPPQMVRPLVPPTVPARRQGVNRPADEGMDDAPPTYEQAQAAAKYEPPPGHPHHHASSPVNRQGNGGAGPSFPLSPSRPGMGGGRGRVLGPGGVVGSSQGGRERDCIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGS3</accession>
    <name>A0AAD8UGS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cysteine alpha-hairpin motif superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_752980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364047.1">
        <property type="nucleotide sequence ID" value="XM_060514286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGS3"/>
    <dbReference type="GeneID" id="85398184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000004">
        <property type="entry name" value="Cytochrome c oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="74" mass="7776" checksum="8EEDFD32873E846A" modified="2024-05-29" version="1">MASQAAALPSIATPAAAPAASQETSKPKPCCVCKDEKAKRDECMLFSNAADPSKDCLSTIDQYRACMKGFGFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGZ8</accession>
    <name>A0AAD8UGZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_761631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360485.1">
        <property type="nucleotide sequence ID" value="XM_060515191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGZ8"/>
    <dbReference type="GeneID" id="85399089"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="206" mass="22512" checksum="EB03A4628F304FE8" modified="2024-05-29" version="1">MRARGKGTRKESPAVWYGKVSAGKVGSREGTYNEADNMEANTSVNRQQTTEPTTHPKRKRAQVEVAVPLPSLLAPDDAAVSTDGTGLLDFWILDSGLTHAGLKVRLIPVVPRAHSVIRLRWQGTGTSCPPSVYEYALLRRAELKVLWAVSGTADEVPWSVLPHVPHLTTAHLWLQPLPQPTDGFSSCRSYLRLSSIRGGFSIPVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIA2</accession>
    <name>A0AAD8UIA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_631090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361834.1">
        <property type="nucleotide sequence ID" value="XM_060508882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIA2"/>
    <dbReference type="GeneID" id="85392781"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42678:SF34">
        <property type="entry name" value="OS04G0183300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041906092" evidence="1">
        <location>
            <begin position="21"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="55"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="558" mass="59903" checksum="0884E9FCF03905EA" modified="2024-05-29" version="1">MLSSSLLKAVICLIWPSSEWTTCEQKPASAIPSLLDATLDDLNHGLHSGIFTSVDLVNAYIERIKETTPTLNAVTEINPDAVSIAETLDLFRRQGGPLLGPLHGIPVLIKDNIATADKMNNTAGSYALLGAKVSEDSTVAAKLRKAGAILLGKAHLSQWAECRSSNSSNGWSTYGGQTLGAYYPFQDPSGSSGGSGVASSVGLAWASLGTETAGSILLPSDVNNVVGIKPTLGLTSRYLVVPISEHQDVVGPIARTVKDAAHLLGAIAGVDPSDNYTSAFPFPKTPDYAAACVKEGLLGKRLGIPRHVLHDPQDAPPSNYSVTVFDSAVDILRSAGAEIIDDIVLPGYNATEISALLIKSLHADFAVAIEKYFGQLAFNPYNITTLRELRDWTQHDPREQWPEKNTLSWDNNLAEGLRNTDPEFWNVHLRLLYLTGPQGYTGALKNHSLDAIVLPTAFAVMNAAISGTPVISVPFGRHPDDTDIVKDKTGTLNAVAPNLPFGIGFAGAPFSEETLISIAYAFEQKVQAREVIKPYIKPKTDLEDIVRHRAEVENILEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIK7</accession>
    <name>A0AAD8UIK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_754764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361969.1">
        <property type="nucleotide sequence ID" value="XM_060514525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIK7"/>
    <dbReference type="GeneID" id="85398423"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="16715" checksum="0D4426B0A30DFBEF" modified="2024-05-29" version="1">MPPKKNSEAGAVAAGLDLTDSEIKLMFGMMEIMTRPSIDYDALAANLGSASANAARTRVATAIKQHPTWFTGPGGASATGEGFSAASNDGSTPVKKPRVKRTSKKKAPSDAEDGENAGEQGTPSKKKARIAKVKEEQEDDTKEGIKPKLEKTEIVDGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIM1</accession>
    <name>A0AAD8UIM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_388598</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363542.1">
        <property type="nucleotide sequence ID" value="XM_060502765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIM1"/>
    <dbReference type="GeneID" id="85386664"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF43">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="93"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="64761" checksum="9183BC9EB797D278" modified="2024-05-29" version="1">MQCIEKHHTMSTATSKDNSVPADVAAAQPSALKSAVVEHPKADADAVAKAEEHIVPPAIQPLQLNDEPSDAAPHTAPESIPPVYITGWRLYAIISGLCMSLFLSTLETTIVSTSLVSITNALHGFEQRDWIVTSYLLTYTGFLIIFAKFSDVLGRKFVVLLSLAIFTIFSIVCGVISSMVQLIIFRAFQGVGASGIYAMVNVINPELVPSDKWGNIVAGTSLVLVFSSVLGPVLGGVINDHSSWRWVFLLNAPTGAFATALLAFLLPSNFPHQGRGVNQPSMRDKFSGAAIARLDFVGAAVLLAASILLVFGFEEAGSRYPWNSAIVISTIVCGGSLFLAFIACEYVVGKPKYPQEPVFPLRLLKDRHFVGLFLTAFFTGLPFMTALINLPQRFQAVHGLSPFAAGVHTLPLLLSSPLAAAVSGPLTTKMDVPPFYLLLFGTCMQILGVGLASSITPDRLRDLLGFEAIMGFGFGMTLVTVLIYVPFLVDRRDLAVSMGAVTQFRTLGGTIGLAVGATILNNHLASSLPNHLTPSEMQSISDSVQFIDGLPAPTRTAVRSVFSEGYNKQLRTMLYFSVAVLVSLTLMWDRNLKRARDMKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ68</accession>
    <name>A0AAD8UJ68_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_628284</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362775.1">
        <property type="nucleotide sequence ID" value="XM_060508688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ68"/>
    <dbReference type="GeneID" id="85392587"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="40152" checksum="004A7A3B1DD2255F" modified="2024-05-29" version="1">MSDHVNSSIVYAALSIGCLISMRRSGTSQETESHMRCLYSNAMVHVEKLHMCPSTALSFKALITLLVASALWKPADADWLLGAAVSCAQSLRLNNLACLKTVCQRNEEVESLKHAFWLLYTIEKPYRLRNGQASALSDAYIDHEPISSGIEARKPSMQAFGVHYRLAQCCARIAGEFDCQKALSQSTIFTSENLDNWLEQLQRLRVDVFTARHQSAPAMTLDPRIASPNSPCMPPSEGDISASLLYFELVLCVSGRFSASSLGDSSSDKIEQKVLESAIDILKLLVEVDPTKAGTDQNLVRIAVSSFCLVATFISRANERTTIFRYLVSTLGFFARMTITAPLMTLGKFSSVVDSVQNVLKNDSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJC0</accession>
    <name>A0AAD8UJC0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_753102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363902.1">
        <property type="nucleotide sequence ID" value="XM_060514303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJC0"/>
    <dbReference type="GeneID" id="85398201"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092703" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="28776" checksum="365E8B68552ECF8D" modified="2024-05-29" version="1">MHILAVLLFGVVFPACARSENRFRRPPGPGPAGDFRDNPVYTLGDNIDLQWEMDLKNIDLILWQQQPTGNIKGPYAKLASNSTVKSLLWTVGYAGSPSTMNPDLSQVYFLQLFKTGQSGSSATSHYFNITEPDSTSTSTTQPATATTTALALASETPTSTPDSSPAQPPTHPADEDQLSSTAVAGIAVGATLGALILLVLLAGLVRKYVKRRRDMAVYTEGDILVYAERQLQAKDEAAAWKLELPAHSRERFEVEACELRHEMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKG8</accession>
    <name>A0AAD8UKG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_720742</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363419.1">
        <property type="nucleotide sequence ID" value="XM_060512296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKG8"/>
    <dbReference type="GeneID" id="85396194"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="50"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="42137" checksum="D7DCC4423356AA6A" modified="2024-05-29" version="1">MSSKILAGLSGRNVSSTAPFVIDVSKDPAPRVVASIWAMISVSTVFLFCRVYCKKIRSRGLWTDDYLLVASWIFLLVSTSLTTELMRLGFGKSLDFSAHIFTLSSVNVVMNKVALALSKTSFAVTMLRIASGKLKVFIWFLIISMNAVLATSAVVAWKAACDRPSDSYEAVLPGSCWRVEDSVIMHMVSNAYSALVDFILSLLPWPMIWKLALKRHEKIGVAVAMSLGVIAGLVGVIKVIKIVTIAEGADIPYRLSLLFIWGQAEINVTIVASSIPVLRVLFTEMYATTRSDERNGYLKSDGQSAFPTEIGMNTLEEGRKIEEETNRNVLLAMGPSTATNSAMRVRETEIGYNAMDEITQGTQRHTLRNSESYEGIELAKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKJ2</accession>
    <name>A0AAD8UKJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_350475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364547.1">
        <property type="nucleotide sequence ID" value="XM_060502520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKJ2"/>
    <dbReference type="GeneID" id="85386419"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="164" mass="18240" checksum="BEA158187206CC9E" modified="2024-05-29" version="1">MCNDTQNSKLSGMRRLIATAIAGMVSVISSLFLKDVIQVYLIETYEMSPRSSTAFGHEREPGQEPHLSAVVCLLIFNIYSISTYSFSFLRRKDQWKNPIVACFFVVSVVAACLRTAALGDSKNSLAYTIATAPLLLPLGLWFSAITHSMWDRWSMRPGDGKAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL23</accession>
    <name>A0AAD8UL23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bud-site selection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_620290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365323.1">
        <property type="nucleotide sequence ID" value="XM_060508187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL23"/>
    <dbReference type="GeneID" id="85392086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037393">
        <property type="entry name" value="Bud22/SRFB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015158">
        <property type="entry name" value="Bud22_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325:SF1">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09073">
        <property type="entry name" value="BUD22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bud22" evidence="3">
        <location>
            <begin position="18"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="56876" checksum="61F6E4105F824C15" modified="2024-05-29" version="1">MVKRKRSREDDLEAKLADYKKEIFRAIKGAKGLERQRYSKRLRDDKALPDKVKRLEREILVLKSLDLQQTADAHLHSSLLKIKQIAESPKLPEEIKQGVPKPDLSEEEKAALHNVTSGLFNRPHVREAVDKAVRGVCLILNVPIPDKKSKKGKRDSAATSESKKQENKEEDDEPRESKKAKLVDAKDVSAKPKAESKSKEAEVEAEEEEPNPFDEMDDEIPTDSDASDGGKNADVADTEEEEVDSDEEEEEKALSKMEAMLGGSDSEEDSPDEDLKARYKALLGEVADEGDTADDESNSDDEDEDSDEEMADLDDDAEDSGNDSDRQRRINAANVSLSPEPEPSSSKEKKVKRAKKPTGRPGETTFLPSLMGGYISNSESEASDLDLAPPKKRLGQKQRQAIWEKKYGASANHVKKQANGQRGAGGARDSGWDMRKGAVGADEDGGARKPWKKGVSNPLGGGGGKGRDRGGRGEEKKKPRVPLKKDDEGILHPSWEARKKAKEAQTTAAFTGTKITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULF2</accession>
    <name>A0AAD8ULF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MAPEG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_382186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363753.1">
        <property type="nucleotide sequence ID" value="XM_060502714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULF2"/>
    <dbReference type="GeneID" id="85386613"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="16336" checksum="F0B8F50843D34B25" modified="2024-05-29" version="1">MPLTLQVPDEYGYVLLVAASTFFINTTHVLLTSKYRKASGLVYPAPYASNEQADKDPKAYQFNCAQRAHANFTENQPSFLGALLISGLRFPVASAVLGAGWTLSRILYAFGYTSGAGPKGRTRGSIGSFLFDTALKFTSTYTALAMIMNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULV1</accession>
    <name>A0AAD8ULV1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_268018</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366286.1">
        <property type="nucleotide sequence ID" value="XM_060502037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULV1"/>
    <dbReference type="GeneID" id="85385936"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000003">
        <property type="entry name" value="Fumarylacetoacetate hydrolase domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26202" checksum="394D8E5930BAC0CD" modified="2024-05-29" version="1">MSMVFRRSMATAASLKRAGKVMCIGRNYADHVKELNNTRPKQPFFFLKPTSSILLPGAGPVLRPKGVDMHYEVELALILGKQVKDLKADDHKGAIDAIEAYALAIDMTARNNQNEAKKKGLPWSIAKGFDTFLPMSDIIKKSAIPDPHDIELFLKVNDVVKQEGSTNLMLFQIPRILSDISKVMTLEAGDIVLTGTPAGVGPAVPGDVIRAGLRVGGKELTEAKIEVAVEESPSSYEFAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULY0</accession>
    <name>A0AAD8ULY0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C6 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_782981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362870.1">
        <property type="nucleotide sequence ID" value="XM_060515573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULY0"/>
    <dbReference type="GeneID" id="85399471"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00755">
        <property type="entry name" value="AFLATOXINBRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="632" mass="69901" checksum="1A71FB9A130C34FC" modified="2024-05-29" version="1">MSTPDDPQIKDSASTPPASLQVPSGRKGTKKVRTGCVTCKIRKVKCDETKPACLRCTKTGRKCDGYLPSPGSDDSISRLSPAVSAFADWAGGSREQRAFDFYRNFSAPSIFSDGVASTLWKKLVPHFCHAEPAIRHAVLAISSLHETLALPSNSDPITEEANNPRVLTNTFAAEQYGKALKCLQEWKPTASSPATVPLLACLLFICIEFMLGDEGASQVHINQGRTILSQLEPSADVDMIKKHFVPIYSRLGLASFLFGSFPAAIPATLQSSPATNLYFASVDEAEVSLYELIDDGLRFTAQAKRAVYSYQPDDPTLLDLAHEQDDFLARLTRWHIAFVVVSATSTDDNLSKRKLCMVYYHAARIAISTAMDPKEIAFDTHTTAFASIVSNSAEFVQATRKTVRDPSEAAKSMPKFVFDTEVIPPLYYVSIKCRHPMLRRAAVSLLKQDAVTNRRENLWDAQMLAEIGKRYISIEEEAARHREEAFDITAGWDTASWEGSDGVPTGLFPAEMESGMECDYPVPRFQYPQIPKATNSQQNEEYERTRILVNDLMLDSHLTPRSASTGSTPSSGSIGNFGAFQLEPPFGLPEHARIKNALIDNEQRRGSWVTIFMDPEEAGATNWKVTKEFISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM23</accession>
    <name>A0AAD8UM23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_278165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365908.1">
        <property type="nucleotide sequence ID" value="XM_060502112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM23"/>
    <dbReference type="GeneID" id="85386011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="9847" checksum="CD79101BC8592281" modified="2024-05-29" version="1">MSGMRRSPYLGMRIARFPAPNFVLTETTPFAMLMLSACWLPANTFEVQAAVIDPRTPYSHIRVFSLDCPLISHHVSACSRMDVMDVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPJ3</accession>
    <name>A0AAD8UPJ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNL zinc finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_651626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365091.1">
        <property type="nucleotide sequence ID" value="XM_060510464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPJ3"/>
    <dbReference type="GeneID" id="85394363"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="79"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="189" mass="20795" checksum="07969A42DE70B5EF" modified="2024-05-29" version="1">MASRSSFTRFAPALRQARPGASPFNRNSPILSALKTRQQLQRTPALLQPQIAARFAHTVPKPKAAREAEAKTPAQMRMETSPHYQLDFTCVPCDTRSRHKVSKQGYHHGSVLITCPSCRNRHIISDHLGIFGDRKVTVEDLMREKGRLVKRGTLGEDGDIEFYPDESVAAADGADAEAQAAESKKDGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPZ0</accession>
    <name>A0AAD8UPZ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_751856</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365301.1">
        <property type="nucleotide sequence ID" value="XM_060514107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPZ0"/>
    <dbReference type="GeneID" id="85398005"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="10068" checksum="6B436D520F74923A" modified="2024-05-29" version="1">MPVPFETLIPYGIMIAMFGITGTGLHVIKGIQNGGKKPRWGLDQWDRQSTLMDRDRRLTGDLRGQIANHEAPPGFELNHPWRLEKRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQZ4</accession>
    <name>A0AAD8UQZ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_576271</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365659.1">
        <property type="nucleotide sequence ID" value="XM_060504906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQZ4"/>
    <dbReference type="GeneID" id="85388805"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000059">
        <property type="entry name" value="Serine palmitoyl CoA transferase subunit LcbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="124"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56952" checksum="B1713D0A5CF2C059" modified="2024-05-29" version="1">MDAGEAQTKLIAWLHEASEAFQKVPGSAVLIRYIQSSYQNDPIRSGIELVLFIFFVRYLLSPSYSTQKQNFIKLRDDEIDELVEDWTPEPLVAPQTALEEIEAERLPVIVGPTGPKTKLANGRTVTNLASYNFYNFNANEQIKDKAIQTLRTYGVGPCGPPQFYGTQDVHMKTEADIAAYLGTEACIVYAQAFSTISSVIPAFCKRGDIIVADRAVNYSIRKGMEASRSTIKWYNHGDMDDLERVIRKVVKDQKGKKLTRRFIVSEGLFEITGDSADLPRLVELKHKYKFRIILDETWSFGVLGRTGRGLTEAQNVDPSQVDMIAGSLAGPLCAGGGFCAGAKDVVEHQRLTAASYTFSAALPAMLAVTASETLSVLQSNPDILTQCRENTKAMRAQLDPRSDWVVCTSSPENPIMLLVLKAEVVAARKLTREDQERLLQDCVDEALANGVLITRLKSMPIANDLNPKDDSWQIQPALKVCLTTGLPRKDIEKAGVTIRHAITKVMTRKSSSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URV1</accession>
    <name>A0AAD8URV1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_253026</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366794.1">
        <property type="nucleotide sequence ID" value="XM_060501942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URV1"/>
    <dbReference type="GeneID" id="85385841"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000007">
        <property type="entry name" value="Cell surface Cu-only superoxide dismutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232946" description="superoxide dismutase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="25960" checksum="BAFC46B6E4A26F5E" modified="2024-05-29" version="1">MKSFSIVSIIAAAAVGRVASQSTGELGDATIVSNPAGVVYEAVLPEKPFYKAGSLEGNVQGSIVAVTAPDGKGVEFKVRFSNLPKEGGPFTYHLHVDPVPEDGNCTKTLAHLDPFIRGEATKCDSSKPETCQVGDLSGKHGAVAVDYEKTYVDPYLSIVEGPGSFFGNRSFVFHFANKTRISCANFKLITKPDSHDNCSTTTAATMSGTGAAPTATSSPTSSIVPFPGAASTSGASISLMIAGFAAVLFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US40</accession>
    <name>A0AAD8US40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_791287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366351.1">
        <property type="nucleotide sequence ID" value="XM_060515731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US40"/>
    <dbReference type="GeneID" id="85399629"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="26919" checksum="F9EE8B2E0B86CB57" modified="2024-05-29" version="1">MRNSIIAAAASLALGARADIYPNYEYGNMFYLGPTTGGQYITKATYNMEVPNPPTNWVKTDETQRWLSLWIGVQDNPNNGDVLNMNFVQPLLNWGPDNSVWGCSAPNTQWCAAASTYQPSGQIGQAYVPVNKEATLEFEISLNSSTDMIDQKIWQNGDLISSESDSKGMRPAVFYSGNECYGDGCGTLPAYKYTNITLVFDKAVTNLADIVSYTNATHTEWQTKDNGITWTVDSITIAEDNLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US67</accession>
    <name>A0AAD8US67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_265700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366229.1">
        <property type="nucleotide sequence ID" value="XM_060502023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US67"/>
    <dbReference type="GeneID" id="85385922"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="116" mass="12917" checksum="C12FE007366FD32C" modified="2024-05-29" version="1">MTPCQSRTEQSVGKILGQSAISGAYMRSRYSFIQKGGGSLVDNQHHAMHYCYVGGTDSKAMPNHPHGVLVPSQSRQSIPLQQQFDRLAQWTLAEHHIARQPTYDRPSAQSTSSRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USR1</accession>
    <name>A0AAD8USR1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lactose permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_649910</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367128.1">
        <property type="nucleotide sequence ID" value="XM_060510327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USR1"/>
    <dbReference type="GeneID" id="85394226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="37"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="520" mass="57032" checksum="9C21F05F5396481B" modified="2024-05-29" version="1">MGPGSNVEAPFVTAMPEGAVDPKKWWRSKNLRTLNLLLAFPMLSIFTQGFDGSMMNGLQSVENWRNYFGEPKGSTLGLFNAAYPIGGLCAIPFLSFVSDKFGRKIGLACGAILCIIGSTVQASAQNLAMFVVARGILGCGTVFLGASGAPLITEIAHPAHRATATALFNTSYSLGAIVAAWTTFASFRIDSTWSWRIPSAIQGLPSVIQLLGLYFVPESPRWLASKDRNEETLAFLAKYHAEGDEHDALVQFEYEEIQSTLAYERTIDRGSWIQNYLELIRTPGNRKRLFIILWTSCIAQMSGNAFVSYYLSSILSSVGLKSSMEQTLINATQQILSWLSALYFATLPGKLGRKTLFISSLSAIFVCLVCITAGSAIFANNESNKAAGGAVVAFLYLFSPAYNLGLNGNLVLYITEILPYSLRMRGTACFQLFSTCFSLISTYVVPIGLDKLAWKFYTIFIPWVLIEIVVLWFVYPETKGPSLEEIALLFDRPTMDTTTTIGKDGVKHVEIGFAEGTKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT00</accession>
    <name>A0AAD8UT00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">KOW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_695150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367263.1">
        <property type="nucleotide sequence ID" value="XM_060511351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT00"/>
    <dbReference type="GeneID" id="85395249"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22682">
        <property type="entry name" value="Ribosomal_uL24m-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="388" mass="43732" checksum="AE85DDE3DDB6CBD8" modified="2024-05-29" version="1">MQRIIKRTVQAEKQVARRMKKRARGEGGAEKAQRFRDQKNMLTELNQDIKAARLARQEKWDLGPLAPRRDMFETYGALQTNRQGRSTPLKPDEIEARCEWAGGVEYLNLAVKDRVVLLEGPEKGKIDRIASINLEYGTVQLEEIGKVTVHVPESFQNLLDAPTTQNAAMNIPISAIRLVHPIVDPATGVARDVVVRQLARGPVKWSRTTGWRAWTRYIPGANIAIPWPEREAEVREDQPGDTLRLDAEAATFVPTLLSPPMPASVIDELRNKYSRFRTRHEDEYIMRKEAEEAEKKALKKASADALASMRTPLQELNRELRDARRARGKPELSSDMLERIGEIMARNKATVQGDTSAWNVPTPKLFESKTASAATEAPKETESHPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT60</accession>
    <name>A0AAD8UT60_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_615046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366921.1">
        <property type="nucleotide sequence ID" value="XM_060507877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT60"/>
    <dbReference type="GeneID" id="85391776"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="66" mass="7733" checksum="3B3D058E794B8A75" modified="2024-05-29" version="1">MMLTKPDTSTFHHSHIYTLTNDNTNKLTISPTLHIQQGRLSVGKLNHSHESKLDRFTSLWLMHYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTX6</accession>
    <name>A0AAD8UTX6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GCS light chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Gamma-ECS regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Gamma-glutamylcysteine synthetase regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamate--cysteine ligase modifier subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_569950</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of a catalytic heavy chain and a regulatory light chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368822.1">
        <property type="nucleotide sequence ID" value="XM_060504249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTX6"/>
    <dbReference type="GeneID" id="85388148"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035226">
        <property type="term" value="F:glutamate-cysteine ligase catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032963">
        <property type="entry name" value="Gclm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295:SF4">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="11">
        <location>
            <begin position="111"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36211" checksum="4B1BD46EA4639C41" modified="2024-05-29" version="1">MTKLILSTGNIVSGGPSIIRKPGAYRSNLELTNSLRSNFLAAQQDYSPYEESSPIDDDDEPVNGNGLNGHSNGFSHSSNGRRPRIDVWTAREDDALFIPRIDWSYSGLQEEPDNYDVTVKLFFLPNAAAQERAQYVQDALNLVRKELGVTRIDLLIASFPGMSFEGDCEWEADKRNASQGNIDEEAATWTVLEDLYKRGEVKALGISEFGTEKLAKFIKKVSVRPAVDQINIKDCCSVPPTLVKLAKTEGVELLVHTDCTDILPRGTLRELLGHGLQGAGVLADPAEAQEGLEGDLTPEWVVKYTAFVKDRGVIENKGYFAGAELVETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUH8</accession>
    <name>A0AAD8UUH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_260534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366575.1">
        <property type="nucleotide sequence ID" value="XM_060501993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUH8"/>
    <dbReference type="GeneID" id="85385892"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038883">
        <property type="entry name" value="AN11006-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42085:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="309" mass="34660" checksum="B0B12D9CDD634A7C" modified="2024-05-29" version="1">MVRRGKISRAAGSSLDPTPITSTLTTPLSSAYPSTYASEVEIDALGDSIGSLTLSERRAARRKAKPFAFMALPSELRLKIYDYYFEGSGGVVDLDPDNYKTYHKKLGIQRTCRTVYQEVSHYFYSSRSFRIFPTHPGKYFKSKKPLLARMKPSSRSYITSLELRLGPGWSKPPRGWVVTPALGLHECVNVRRLTVLVECDPSDGIFNGFRRSDGFYEGFSQSLLTEVFNQMPWIDTVYFDAWPGVKKSGGMMRALLEVTSANNRKIRWGPERGWTDGPEEDEIKPSNSLVLVPPAPEFNTSTMGVLVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV59</accession>
    <name>A0AAD8UV59_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571559</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367926.1">
        <property type="nucleotide sequence ID" value="XM_060504421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV59"/>
    <dbReference type="GeneID" id="85388320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="60712" checksum="A5D6AB0EE6CBAB00" modified="2024-05-29" version="1">MLIAELVQGLVNEATHRPTEFLAKFLGVAVLVYFIANEVVRSKARLPAWHGPKGLPVIGNLHQLGGNASQVYKDWAKEFGAVYQVQLGNLPVLVVNTAAAAKVMFGNNSQATASRPELYTFHKIVANTAGTTIGTSPYNESLKRRRKGAASALNRPSIETYIPHLDLETRDFLKDALNYGKAGKVTVDPLPLVQRLSLSLAVTLNWGMRFPSHDDGLFKEITTVEGEISRTRSVTDNMQDYIPLLRYNPFSAGKRHAVEMRIRRDKYLSKLNGDLEEKIRNGTHEPCIQANVMLDEEAKLNNVELTSISLTMLSAGFETFTAVSTWGIGFLATHPEIQQKAFEAIRKTYDEGNPLCDARDDQTIPYLRALVRECLRYELDATLLTICDIWLTFLLRFFTVLRLSLPRATNKEFMYEGKLVPKGTVVFLNSWACNMDGDLWHDPEVFRPERWLENPEAPMFTYGMGYRMCAGTMLANRELYITFLRMLASFELSSTDKIDTDPITGAADLTNLIITPGSYKVTFTPRNESALRAALETEVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWG5</accession>
    <name>A0AAD8UWG5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_717659</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367625.1">
        <property type="nucleotide sequence ID" value="XM_060511970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWG5"/>
    <dbReference type="GeneID" id="85395868"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000020">
        <property type="entry name" value="Guanine nucleotide-binding protein beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="67"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="240"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="39732" checksum="7CDD54565F6B0F64" modified="2024-05-29" version="1">MNSQGQNDVSPEAMQARIQQARREAETLKDRIKRKKDELADTTLRTVAQQAHEPIPKNQLMKAKRTLKGHLAKIYAMHWSTDRRHLVSASQDGKLIIWDAYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLNQQREGPTRVARELSGHAGYLSCCRFINDRSILTSSGDMTCMKWDIETGQKVIEFADHLGDVMSISLNPTNSNTFISGACDAFAKLWDIRAGKAVQTFAGHESDINAIQFFPDGHSFVTGSDDATCRLFDIRADRELNLYGSESILCGITSVATSVSGRLLFAGYDDFECKVWDVTRGEKVGSLVGHENRVSCLGVSNDGISLCTGSWDSLLKIWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWP9</accession>
    <name>A0AAD8UWP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_100275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368811.1">
        <property type="nucleotide sequence ID" value="XM_060501022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWP9"/>
    <dbReference type="GeneID" id="85384922"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="92" mass="9906" checksum="CB37D889B672FFF2" modified="2024-05-29" version="1">MIDKKTTKQIAKEVLQQIPVPKHLSQLKKPCSPSVAPNSSQAQNSAVLPVATHVFTTSATKTQEKCKNRPMSPSNSIPPPAPTTRVASSWMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXR7</accession>
    <name>A0AAD8UXR7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_608395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368600.1">
        <property type="nucleotide sequence ID" value="XM_060507480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXR7"/>
    <dbReference type="GeneID" id="85391379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="36184" checksum="9F2E98FDF71BF5FA" modified="2024-05-29" version="1">MHQQKIHFFSVLETYTLGNSSTSVAAFASDLPPVEPVKDRPGDRWDRPEPSQAPTRLVALGPRHLEPLNTRASTPAYSRSASSSSRWTSSWSSRSARSCSSRCSRSADSSSRPRRPLSRARGSAWALLAPPLAAFPPAAPPPMLSRMEERMLLPSAAWLFFAAAPPAALFFLPFLPFFFLPPAFAVPLFAAPPAAPPAAPPAAAPPAALSAPLFFLAAALPLAALAFFPPAAAPSAALAVPLLAAPPLFFLALFFLAPAAPAAALFFLPAALACAFFLPFLPFFLPPALAVPLLAAPPAVAPPAVAPPAAAPAPPAAAASLAAFFVATPFSPAFSPSCWTSALSPAGVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X884</accession>
    <name>A0AAD8X884_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phytase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_642847</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000208">
        <property type="protein sequence ID" value="KAK1707537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358074.1">
        <property type="nucleotide sequence ID" value="XM_060509641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X884"/>
    <dbReference type="GeneID" id="85393540"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003431">
        <property type="entry name" value="B-propeller_Phytase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050969">
        <property type="entry name" value="Dev_Signal_Modulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949:SF56">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14949">
        <property type="entry name" value="EGF-LIKE-DOMAIN, MULTIPLE 7, 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21700">
        <property type="entry name" value="EGF_DL_JAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02333">
        <property type="entry name" value="Phytase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50956">
        <property type="entry name" value="Thermostable phytase (3-phytase)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51662">
        <property type="entry name" value="BP_PHYTASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="BPP" evidence="5">
        <location>
            <begin position="44"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="BPP" evidence="5">
        <location>
            <begin position="428"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1707537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="785" mass="84456" checksum="2D27753A4C91E9BD" modified="2024-05-29" version="1">MINEVFLLIRRALSLHVLSCQADLYRLDLTAMGLKYLACAVAIAAVAMHPWLATATDVEANITALTGGELEADWTNVFYSKEKPLLLGNDGGAATGGFHAWDLNSDSPLSEVKSMITGRTKIITTVYNVTGKDYALTIAMPDSIIRVYEMPEFKEIESAQVTMLGDWAAMCSWRTKSLNDYVFLFGKSVVVQYLVRPTKDSIELVEVQSIPVPTEFSGCAVVQSQAKMVVNADDDKDVYIFDLKESTIAPEITKLGEAAEDVTGIATYASNSTDTEYLFVVQESSIAVYKYPFDLVGNIKLTGLEDIEVQGLSIYQGSTAKYPSGALGFAVEADNVAGFGVVSLDSALDDLGIDANTAYDPRNPTGSRDRSPICDACSGNGYCQENALGCGCFAGFTGDKCDQIQCMKNCSGNGECVGPQQCKCENGWGGLFCSAVLVEASYETDQNGGDGDDPAIWISPESAENSRIITTTKSTEGAGLGVFDLKGKLLQTLPAAEPNNVDMIYGFQAGNRTVDLAFAACRGDDTLCLFEMTSNGTLKDIPGGIQPVPEDYKVYGSCVYKSPTSGKQYLFVNEKSARYLQYELTSNSNGTLQTTLVRDFTGGSGGQVEGCVTDEENAWIFLGEEPSALWRYGAEPDSSDDDAIQIAFVGDGQTFADVEGVTLVYGVRPDQGYILVSNQGVSSYNVYTRADPHYYVTTFTILKSSDGQIDAVSNTDGITAVGTHLGKDFPHGLFVTHDDANQLPDGSTSTEASFKLVSLEKILGADVIKAMNLLDDVDANWDPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9P6</accession>
    <name>A0AAD8X9P6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_638930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359332.1">
        <property type="nucleotide sequence ID" value="XM_060509393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9P6"/>
    <dbReference type="GeneID" id="85393292"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="70" mass="7600" checksum="01456872B26DA681" modified="2024-05-29" version="1" fragment="single">LVDFLRPFSGRVIKGGIVDADGFRLGGEEVPSQVWLDGLKKDWGFAGNRLKEVPINGETVTNRAATISEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAA4</accession>
    <name>A0AAD8XAA4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_75825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359917.1">
        <property type="nucleotide sequence ID" value="XM_060515004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAA4"/>
    <dbReference type="GeneID" id="85398902"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="137"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="51073" checksum="C83AFA49693487E7" modified="2024-05-29" version="1">MKPSLALLGAGSALAFRESKVISSSSGEICISSQLLAASSNNGPICRNKEDLLGGRADQFPFSSAGTSSTPSGSAWTHTSPCFKNGTEAPEFCIYHAANYGGKGISIITDADRAAHVTRSWGFTKPEELEGANQPLPKFEVAKVPGKDYGLVASLPIKRGEIILRETASLLIDYAAFSHIPPDEMKKMQAHAVDFLQFKHRSQWLNMSSHGYHGDHLSMVDKILVTNSFDVEMDDAKRDDDFYAVFVNTSRMNHDCRPNVDYWFDPRTLTQRTVAIRDIIPGEELTLSYIDPMQTRAARRERLHSTWGFHCSCHHCMQHRLKTDESDRRIEQIASLREEFNDYTPASRATPQMAELLISLYEQEHNWSLLTEAYTLAAIEYNGIGEPWLATKYARMAVEYGLTTLWEGHGDVIEMTKLAEDPWSHWSWMLRTRKRYSWGPGPKVDLDLDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAM1</accession>
    <name>A0AAD8XAM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_680575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360262.1">
        <property type="nucleotide sequence ID" value="XM_060511202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAM1"/>
    <dbReference type="GeneID" id="85395101"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1715463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="33673" checksum="35403465337C177F" modified="2024-05-29" version="1">MTGVVGVNDMDGVSLSDLDDPPVYNITCPDKWQVYYYNWWPLLNTMCRTVAKMGGAWTDGPWTGVFGGNQAKIDRARKVTFDWVQTGEDCQGSCVQVFSTLRNAGPCRGDEFWMREKINMNYEGCGIAKFEYQYQQQAVLENGRGECWNTKDYRPTYLPVKAIVKDFCEQSIKVIRQQGADQFVKDVSRGKDGHYFTSYNRQVDDALNKTRLYDVGMIHFWIKPRNNTIACPAGKTVQDIIEDKVDGLSEALCQQRILSIENMDCGAPLGKSDGGRLFADCFEWGVEASGYNGIDILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAZ1</accession>
    <name>A0AAD8XAZ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMMECR1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_589503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359651.1">
        <property type="nucleotide sequence ID" value="XM_060506239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAZ1"/>
    <dbReference type="GeneID" id="85390138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.150">
        <property type="entry name" value="Hypothetical protein ph0010, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00296">
        <property type="entry name" value="TIGR00296 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="271" mass="29888" checksum="1AAD57BD2E196304" modified="2024-05-29" version="1">MASVEHCLYCFEALASHLEKRPGLSLKEIKQSWPEYAKTLSPGFGDGKDGKKLLPALQRLAEPSSDSASASSGSSISLPAETPATSTDSLADDDEADDISESPLFVTWNTVSSCSGHRSLRGCIGTFEAQDLADGLSSYALTSALHDMRFPPVEAPELPSLEVAVTLLTDFEDADDAMDWTLGVHGLRISFFYHGKRYGATYLPDVAVEQEWTKEETLVSLMRKAGWMGSKSKWQDVELKVVRYQGKKESLEYGEYKKWADWVQKNKTKCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB31</accession>
    <name>A0AAD8XB31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_593173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000207">
        <property type="protein sequence ID" value="KAK1707551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358088.1">
        <property type="nucleotide sequence ID" value="XM_060506602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB31"/>
    <dbReference type="GeneID" id="85390501"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000155">
        <property type="entry name" value="Zn-dependent exopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041959598" evidence="8">
        <location>
            <begin position="19"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="9">
        <location>
            <begin position="72"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1707551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="448" mass="48974" checksum="B8116D7E9D9DF980" modified="2024-05-29" version="1">MKTTQACALLLLALLGEACLLPGEASGGRIARRQNMSSNNTGIAIGTGDRFDGGKKLPRGLGIQPAGTNLTTLLNVNEIKSAVKGLVKEYGLEYFESPYKTYENASFFGAKIGGEGGNCSDAHHVYFNAAIHARERGSSDNIIYFISDLLYANKHGEGLTYGGRTYTNDDVKRALSTGIVFTPLSNPDGVAYDQATHSCWRKNRNPAASGGNPEAIGIDLNRNFDFLFDFPKSFAPSVGPNVASEDPTEQTYHGAAAFSEPESKSIKWVMDQHKNVKWFLDIHSYIGVVLYNWGSDENQLRQPYMNFKNESYDAVRGLMPDTPSNNGVYGEYIPSNDWSEKVFAAMRMGNAMDAATGRHYQVEQSSYLYPTSGSSDDYAYSRHFTDPSLGKMHGFVVEFGFGNDEVDCPFYPTPSQYNLNLLETNAGFMEYLLAAADLGVGEPASCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBN1</accession>
    <name>A0AAD8XBN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_455647</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361779.1">
        <property type="nucleotide sequence ID" value="XM_060503188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBN1"/>
    <dbReference type="GeneID" id="85387087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF59">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="35"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1720268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="552" mass="61048" checksum="FF7A76FAA7CDDCA3" modified="2024-05-29" version="1">MGVKQVFTESTFAKYITAIRESPRELISNRKLLLTAALYATSGIPITWDQGSSSVVPSLPGFQKDFGITSATNPTQVSNFISFVYIGAGIGAGLSFFLNDRIGRMWSYRLYMTIWIIGQIIATVSMGNIGALYFARIVSGMGIGALTVTGPVSIVEIAPTEIRGLLAVWFSVAMLLSLTVSVFIVYACFIHVAVGRLQYQIVFFSPTIVMVILIAASFLLYESPRWLFIARRDDEAIQNLTALRGLPVDHPRVATEIEDIKDQIAKEEEKFGRNPGFIVLVKDAFLVPSNLRRVQQAVLSYALAQLSGANSVTSYLVPILSMLGLGGGTARSLFLSGMYSMAKFFFTLIASFFFIDALGRRRSLFTGITIQMISDLYIGVFIKYRQEGNVAPGSSEAAIAAVFIHGFGYAVGLLVLPYVFGAELWPNHLRSFGSAFAQFFHWLFFFGVNKGMPSLLSQTHNWGAFIFFAGWCFLSLIYVYCVVPETSLQSLEQLDELFKGPWWNVSRRAKQLKQQAREQEAIIDAQESVSDQNSEPESSIEKNGARAVSQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC54</accession>
    <name>A0AAD8XC54_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_655270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360911.1">
        <property type="nucleotide sequence ID" value="XM_060510790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC54"/>
    <dbReference type="GeneID" id="85394689"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="503" mass="57271" checksum="4D7D07FA976E93BC" modified="2024-05-29" version="1">MTACKSVAASSIQASSALFFTAAAQLSYRRRQYGTSWYDDADESGGDCDLCTVEDGEEDDNERWWEDSSAIEDEDEDEYDMVQDFVPEERTQQKLVVPSVMLTTTEGNIFFGSAIPEGTWCTESRESLDLRIKHINNAETFLCPGDWRRLRNTFRLWQQQEYDQQLEQERQQEEKAEAALREHQQLYAPLIFLTTPEGDVLTGDEILKGQRAYKSRETRRIKQQYAANAETQLCPGHWEKVRDANRPEPEEDPVLQANQREESTYSKGSRSWHKRLARVNQRSQRRQARQQKFEEAERLWRLQKVEVEEFVAERKAKSSQVVPACTTGVSSDAGIPDLHVHLPMRERRKDDDEKGKEGTKTHSRAGLGTVYCGTEENPTDRPSGQSASAGSQRRPGGQAPNGKRPFRAPHAVFYGLPTTIHSRHPKTTSLWTTTPTSGVAKPEPSPDLPARSCHLVPHLALPRQPLRKRRHNKLSFVGYADTAYTVTKRAIGKWRGLILTLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCF4</accession>
    <name>A0AAD8XCF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_640833</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358735.1">
        <property type="nucleotide sequence ID" value="XM_060509521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCF4"/>
    <dbReference type="GeneID" id="85393420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1710039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="205" mass="23343" checksum="6A9758C00D7C5E4A" modified="2024-05-29" version="1">MHLKEQLNLAVGGIHTTSAVLTQTLFELSAHPEYIPELRKEVVDTLVKFEGAFSKAALWDMHKLDSFIRETHRLNSPNDILATLQRRAIQDVTLSDGTFIPNGTKLEFPTFAIHRDSEFFDNAPDFDGFRFLKLRQEDDKEGGKHHYVSARRDMLGWGLGKTACPGRFLADVEIKLIVAFILMNYDIKNPDGQGRHAHVHFENQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCQ1</accession>
    <name>A0AAD8XCQ1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8035 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_122413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359005.1">
        <property type="nucleotide sequence ID" value="XM_060501157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCQ1"/>
    <dbReference type="GeneID" id="85385056"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058348">
        <property type="entry name" value="DUF8035"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26118">
        <property type="entry name" value="DUF8035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8035" evidence="2">
        <location>
            <begin position="271"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="63009" checksum="A8EE2395ED4989B3" modified="2024-05-29" version="1">MAGRAERWDRDRFMQERERDRYPDDRRYPDERSRFEERSRFEERDDYRPPPRRGRDHSDERFDRGPFDRGHRGGYEEDFVRDRRYVEEDRYGPRRGEPLDREFDRRLFFEKEQREVREASPPRRPTMLRRQSSLDTFDRRPLRFYEREEYPPPARREDVRPRDDYRAPPYVPIPLPRTRQLGPAPSQRYDEIQIAEPGYYGDEEFRGMPERVKEREVVTSRRRRDRSRESRVSRSTRKSSHRSSSRSSSTSSRSTSTTTKTATTVRSSYPKKGKTRIPQRLVSKRALIDLEYPYIEEGNTIIVLKALGQDNIDELLKLSEEYKQSELEIAAARSSAGKHEERHEEIYTIPPPVAALPPPPPTVIHVPPPPPAPASVAPPPAPPTVVSAHPPAPPSVYYEAPPPPPPAPVQEVVNKTTIIRDVSPARSSTSYTTSTTATPVVYERREYSEEVPIGPMAVAERRRSRSRSRKNIRSEIKALEAELHERKHGRSRELVRAEQMPDGAVVLFEEKVEKVEEPRRGVRIEKDKKGRMAISVPKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XES8</accession>
    <name>A0AAD8XES8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_580265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363731.1">
        <property type="nucleotide sequence ID" value="XM_060505332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XES8"/>
    <dbReference type="GeneID" id="85389231"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="139" mass="15894" checksum="D239661DE135D054" modified="2024-05-29" version="1">MEQQLGFTMRPLWSGTRTVSTWEHFDTFSARWNSICSNLQDCKMILHSLTRADWFCKYAGAPSKERGGAKLSNDLLNGRRDIQNQVGREMIKEKTSTQDWITTDDFEIRDKAGDLVLKGGHLGDKKRRQLALRSSEGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEU6</accession>
    <name>A0AAD8XEU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Riboflavin transporter MCH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_742870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362183.1">
        <property type="nucleotide sequence ID" value="XM_060513123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEU6"/>
    <dbReference type="GeneID" id="85397021"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="28"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="46956" checksum="B4F7C9846FB16EF0" modified="2024-05-29" version="1">MTPKNIIAHVTQQEPHRRHAADVECRKSEWVYVLGSFLFLMPSFGFMQSSGAVQSFLLENQLRDYSARDVGWITGVYSFLTMLLDIQAGLLMDVYGPKFLEPLATGLLVLMSFVLAECAEIWQFILCLGVLGGFGNAIATTVGIAVIGKLFIRRKGLALGIALAGSSTGGIIFSLALGQTLPWWGWAWSMRAMGFLAVFIMSLGITCLLPFERLHAMIDSPRVSTKRSSKKAVIGFSAFHSLPFSLICGAIALLEFVIFGATAILPTLVALSGFPIEHGFNMLAILNGFSSLRRILPGSVGDRLGHYNILLVMIVFTIICTSATLTAFGSTRIEALYAFSALCGFGTGSFLSLAPACIAKTREPKDYGRYYGTMNFVISFSLLLSMPIGGQMLQSLGATALSGLYLAVVFAGGILVYAGRSVAVGYWANFRERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF25</accession>
    <name>A0AAD8XF25_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PinX1-related protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_624334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in rRNA-processing at A0, A1 and A2 sites and negatively regulates telomerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PINX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364046.1">
        <property type="nucleotide sequence ID" value="XM_060508437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF25"/>
    <dbReference type="GeneID" id="85392336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF31">
        <property type="entry name" value="PROTEIN PXR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="G-patch" evidence="9">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="142"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="38995" checksum="E12FF632D29292AD" modified="2024-05-29" version="1">MGLAQAKTRRKIGKDPNNTKWTKDLDSFGQKILRSQGWEPGQYLGAKDAAHAVHHTAANASFIRVALKDDMLGLGFKQARDDRVTGMDVFSDLLGRLNGKSTEVIAKEQEARTALKSTLYCDNKFGPMRFVSGGFLVGDKIKEEPTAEAKEKDDSDSDDVKMEDAPATAESSKKSKKRKAEETSEDDSSSSEDEKAKKKRRKEEKKEKKEKKRSKSKSAAKEDASEDTQDETAEKKAKKDKKKSKKAKKEAADNSDEDESSDDKSSKKKRKGETDAEKAARKEEKKRRKEEKRAKKAAAASASASTTPTASGTSTPVLRGHHAVRSRWIAQKRMATMDDKALNAIFMVKSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK9</accession>
    <name>A0AAD8XFK9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_652118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364511.1">
        <property type="nucleotide sequence ID" value="XM_060510503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK9"/>
    <dbReference type="GeneID" id="85394402"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="34276" checksum="1E9DA825310A2A90" modified="2024-05-29" version="1">MADDFAPPSGPPPPKAPEVPPGWIARWNDQYKEWFYVNLHTKQSQWDKPTEPALPPPPPPAEDGHPGGPPPGYAPRPGDHPTPPVDQKHNPYDQKGNPYENQSSTPQPPGAGGSNTMSEDERLARQLQAEEEARARSGGGGGTHSPMPPGYNLQQQQHQQSQSPFPDQLPPRAQETRGKSSGGFLGKLLGKAKTGGMGGSSHAQPQYGGYPQQQGYGGYPPQQQYGGYPPQQGYGGYPQQQGYGGYPQQQGYGRGMGGMGGMGGGRKPGGGGMGMAGGLALGAGAGLLGGALIADHINDEQQEAYADGYNDGQDGDDFGGGDDFGGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGB2</accession>
    <name>A0AAD8XGB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">QDE-2-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_729174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366939.1">
        <property type="nucleotide sequence ID" value="XM_060512815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGB2"/>
    <dbReference type="GeneID" id="85396713"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="1">
        <location>
            <begin position="321"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="60796" checksum="D2A6420A0239F8EA" modified="2024-05-29" version="1">MAVTQAEQLDRLFGTFGDEIFFEEGASQELEDTPEEIVLDPLLLDRQIAARKAAIQVKSVTKPVEKKAPHYIGPPLEPSKSEKLAPADFNALMKQDFPEFKGMKTGDLSAENMTFVSWDVVQRYPLNFIGKTNRPKATPFFDDIAEEHTWDFFYVYHPKALDQSPYIFVPTIQFQHFLDVVNASIQTKLTIPAGKPGEMFYLVFGSSCTIRPKYIARSASHNEYRALDDAIPLPEDDDACDDATVFGMETLMNLLNMHANFKDIKTKSKKKKQNKALNRAESLYDAQLYLGLRPKASDVDEKNKKVELDKPVPHALEQNVVFVCIDIEVAEEHHGTVLEIGISTLDTNDLVGVLPGQNGSNWVPFIKNRHLVTYEYRHIRNRKYIKGCPELFNFGLTVHSKSEYPKLNDLPDKVHAAVSDLSFDNKEDAADKDKRPRTIVLLGHDLGADLGYLDKMGVELWGISGVASRTLDSKDMHQAWRGESQGRSLGMVLTDLGIEHSNLHNAGNDAAYTMQAMLGVAITERVDKDQGHTEKEQVEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGF7</accession>
    <name>A0AAD8XGF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_750905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366352.1">
        <property type="nucleotide sequence ID" value="XM_060513981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGF7"/>
    <dbReference type="GeneID" id="85397879"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000015">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="295" mass="32799" checksum="1FC32A42F8B60836" modified="2024-05-29" version="1">MASALTLQSKQKLNNGLEIPVLGYGLWKTAPEQAEEVTTEALKVGYRHVDSAASYKNEAGAGAAIRGVEDIPRSDIFFTSKVRYINYDDAKDQVEDTLEKTGLDYIDLMLLHCPYGGSEGRKGAWKALVEAQEAGLVKSIGVSNYGVHHLDELETHIKELEEERGGKGKGGAINVAQYEIHPWCARNDIVQWLQKRDVAIEAYSPLVRGERWGDKTLKALAEKHGKSEAQILLRWSLQKGYIPLPKSVTPTRILDNTKIYDFQLTDEDVKNLETDEYSPVCWDPTVSPLDGPKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGU7</accession>
    <name>A0AAD8XGU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Branched-chain-amino-acid aminotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_582170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362920.1">
        <property type="nucleotide sequence ID" value="XM_060505527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGU7"/>
    <dbReference type="GeneID" id="85389426"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009081">
        <property type="term" value="P:branched-chain amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825">
        <property type="entry name" value="AMINO ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825:SF2">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="394" mass="42658" checksum="7490A2DB5CBBDB6B" modified="2024-05-29" version="1">MGSIPACSSAPGESESEILVAVRPPKTNVDWNKIGFTPFQVNGHIECTFTAKSGTWSQPRWVQEPYLKVHGLSPALNYGQQAFEGLRVFRSESGSVQLFRLTSHAARFARSAAAVDIPAVPVDLFAKSVRLAVQLNSEFVPPFEGGCSMYVRPVVFASSPTMNMYTAEEYTFAVLVTPVGLLYGVTGLKALVVEGFDRTAPKGTGAFKVGGNYGPTIPIMGRARKQGYGLTLHLDAETQSFIHEFSASGFIGIKAESAETGAPPTMVIPKDEHILPSITVDSVGQIAQELGWKVEKRPIPFTELGDFSEVYTVGTASSLVPVSAVERESTGERFAFTVDAQSPQSAYARLTDRLQGIKRGLYTEPWGWVEELDGVALRNDIERITNTGSVKSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGZ5</accession>
    <name>A0AAD8XGZ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_239718</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366937.1">
        <property type="nucleotide sequence ID" value="XM_060501866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGZ5"/>
    <dbReference type="GeneID" id="85385765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000692">
        <property type="entry name" value="Serine/threonine protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="16"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1726882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="60586" checksum="B5E8BE4CBED11635" modified="2024-05-29" version="1">MQQSQLDPLPSDLPFRVISKTIGRGAYASIKKAVPLDANTPVFAVKFIHKGYAVKHGRVSAKQLLMEVSLHSHVGQHPNIIEWFASGEDSNWRWIAMEFADGGDLFDKIEADVGVHENIAHLYFLQLISGVSFIHSKGVAHRDLKPENILLSETGSLKLADFGMSTMFEYKGQRKTSSTLCGSPPYIAPEILACGKAEKKANPDAIKYSPDLVDIWSCGVILFVLLVGNTPWDEPSKGSWEYQEYVRTNGRSTDALWGRIPSDALSLLRGMMNIDPSKRFSFRQIRQHPWYTRQNPHLTSDGTISDPINLATQMLESLKIDFNQHPTASQGNPSSSDPMDIDSAGKVSFTQPETPINDVAWDWERPALKVMNPIAVSSTQPLTRSVSGVANRRLFMESLAEEPSISQFSQTPGVPLTLTQAARRFRDIVPFESLTRFFSHVPPQLIVQMLSDALHQLNVPLPPVTPNLYSDHIVIIKIKTLDARRQSLHGEIHVDKHKLPEEQELLDIRFVKIKGDPLEWRRFFKKIVVLCKDGVYVPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGZ9</accession>
    <name>A0AAD8XGZ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_572132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDUFAF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367674.1">
        <property type="nucleotide sequence ID" value="XM_060504472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGZ9"/>
    <dbReference type="GeneID" id="85388371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05125">
        <property type="entry name" value="Mth938_2P1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1230.10:FF:000005">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone]alpha subcomplex assembly factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034095">
        <property type="entry name" value="NDUF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="23929" checksum="189AA152802346AA" modified="2024-05-29" version="1">MNTSATTRALRGFARTQRTVPRSIPRASATSLRPSAAAAAQPLCMRSHFHTTPFRSKNEKPKDYQGATDFSEMDVLANTPIPSTSIDACVWDGFHLNSGVKIMDGDAALLIGGEAFEWRPWEAKGSKNLINAKGQFELPAEAFGLLDLVWPRPDLLIIGVGPKIVPLSPATRKHLSSLGIRVEVLDTRNAASQFNLLATERGVDVVAGAMIPIGWKEGKGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH94</accession>
    <name>A0AAD8XH94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_180916</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367959.1">
        <property type="nucleotide sequence ID" value="XM_060501521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH94"/>
    <dbReference type="GeneID" id="85385420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102050" evidence="3">
        <location>
            <begin position="17"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="30952" checksum="689C90CB301E65BE" modified="2024-05-29" version="1">MLCLVQLLVIVVRSSPMTDDQGPSILGCWILDAGSGSPDLWGVSNLSRSGDSLVRLGGVRLRALVALLGINKLGSSACNYLFSSTSCAKRMSLRLCLLFLLLLPQLVSAVVCHCHVIAMNRLSWLILFEGSWETPKYEVTQLPKVQRSSPLTDRGARQSAERILITKRPKMLPTVTTSFPVFVLVMMVGGSRPWWCWCGKTAASSKVGGFRRKQNSRTKRRRVKFRSSRDETRRQRAKRRLARKPILLFLVPSSAFLSFPSSLFLVSRGGFSFSSASVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHA0</accession>
    <name>A0AAD8XHA0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_168067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367989.1">
        <property type="nucleotide sequence ID" value="XM_060501440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHA0"/>
    <dbReference type="GeneID" id="85385339"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="27931" checksum="4F6195E09E4D30F6" modified="2024-05-29" version="1">MKYACGAPQRRNGPELGNRINGLHSDREEQQYPLPVNVIAAPARPASSERGMGRTVEIGTSKEERERARRTRPGNGRPLIVSAARPEAEIKALSHLGRRRNAETFLDSIWSREATKLTERRFGDRLNYRTLPRAFWETQGELYFDYMHLESATAVSSSRRLFLFVRKKKLHQRGEGAGLRYCGREDFQLGLEEEEGGKPTRNWQGPLACHEAGGLLPMRSLDALEASRHLSMSRSSEKARGPRSMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHX2</accession>
    <name>A0AAD8XHX2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD and RING finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_718169</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367046.1">
        <property type="nucleotide sequence ID" value="XM_060512035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHX2"/>
    <dbReference type="GeneID" id="85395933"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047157">
        <property type="entry name" value="PHRF1/Atg35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12618:SF20">
        <property type="entry name" value="PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="157"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="338"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="415"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="576"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="76442" checksum="37D8F41C45B1EA46" modified="2024-05-29" version="1">MTEPDQCIICLESLQHPSLQQQQQQQQQQDAATGNGAGSAAAKATASTTTTTTTTTTQPTYRAIDSDLEILEEPESNYIATLVGCNHVVHDQCIRSWAKNSNTCPICRTPFNEVSLSSELNGPPIDSYAVQDKKQEQEFDIHRWLQENPEGEGEEPSPACPICESSDHEEVLLLCDGCNAAYHTHCIGLSGVPQTESWYCFECDENNNASRSSPSEASDVEVIQSRPLNRAARSANRRNVTAQRGLLRTQLQARNARREARSLEWQGAWDRIASRIYDATDIDLDNHEDEDLFQGFRRAQAQRGHFRDIQEHQDWEQRMSIASRLGARDIFARNIRPTVGHRLDGGPVEPVMQPPPPAPETREEQQAWGALERAREAETSAPNPRKRKSRSTTASPQEPAQEPERKLKRPRTRRLPLQGEGSASGSASASVSGSGSGSGTASSAGPSTVSALAPAPTITSSPAPTSLLASRPQTNGATQRVQSPINTEPGPSFLSSLLKEVEMSAPSDDETVRNYFGTHSGVDPSSPVTSPSPSSRNSPRALSLTPPPHPRPSSPTLSLSSYVEPRFPKANYSPTRNAGDSSDSDSRSNGAEIRQPRPQRPNRQRPTFARSQDSSPTRSAIPFETKERISGIVRAALKPHWRAKELTTDQYANINRDVSRKLYDGLRDPQTLDDDAKKTCEKIATKEVARAIEELKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIA8</accession>
    <name>A0AAD8XIA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_354259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364480.1">
        <property type="nucleotide sequence ID" value="XM_060502539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIA8"/>
    <dbReference type="GeneID" id="85386438"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="564" mass="60905" checksum="EE20F66F67A0A9E0" modified="2024-05-29" version="1">MSSPPDFRRWPRAVRMKRWLDWAKSQKLPAFRNYPDKAARVDKELRSVFWDFDLTGLPQLADQECWQRIYSALQFPVPNPNEHYYITALNVVDCEVSRILNNGSMHQTLVDLAREAGFDARKCCDPSLSKEQRQYKPPKGPEQVNSANALDLEAFSLEGMDMSGPLNYAAIAGLFLQPKTIKANNEAAAAARDTPASAVPPSTGNEGGSHRCASPSSFVGSRTEPKTLAQIATVDENSCLKPSRRPSSIQEPGVAGRLSSEGTIRNITDQTAQPMSNDTDSKTTFNGFVIPKRQRGGSVQQDRGIAAARPESRSATSTASGGGCGSRPALPKQPPAGLPLHTQRTSEQQSRRESSGSLSGALPQHGALVRRPSGTKGSGLLTPSTPLPQAPSGNTQQHGSLVVKTESQEQSASLAEHKTASQPVGVSTQGSATQGQAITAAMTKKLEATIDQHLLIAIRGVYRSVPKLMEGKIRGWLDGQEYRSMGFAVLRDVESETTKTVRESLITKMKAMEQIVKGSDNPYHAESVRDTKRKADEKDAEGGDESQQAAKRQRGDGVGSGCTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIT3</accession>
    <name>A0AAD8XIT3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_577464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365035.1">
        <property type="nucleotide sequence ID" value="XM_060505022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIT3"/>
    <dbReference type="GeneID" id="85388921"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="29"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="528" mass="57587" checksum="7A91E9C2A0273F09" modified="2024-05-29" version="1" fragment="single">ASQQDANVPLFMTGLLLPHALCTIFIASRIASRLWVTRKWFLDDTLILIAWLFSTALCVVYSITATTPSLLGATSPSSTATADTDANPYIMRTYLGLVYYQLALCLTKLSILALYLRVFASSSRPRERLLARAAVAFVLLYTLPLLLMSFLQCNPVQGQFFSRPTPVCFRFPDLLIASASLHSATDAWLVAMVVPSVARLDLPRRQKIALASVMSLSVFVIVASMVRLQLSLHLHYRPTDDAGVRNTLGFFVMTVLECDLALICASAPTLRPLLARLFPSVMMSGAKRRSLEAGGAETQSFDLTSLTYHGYPWTEPSTPAGLAARSRNASIASHLNKLRMPAPPLPTLTMAQLGPAKLSLGNLLITGTAPRRPGRSWHVAEDGKPILFETAERRGMGAAGYKTQASSIYSQDMTCSGDESWREEEEFEKKGGVILKTMRLSLRSEYATQNETDGVDKEIAGSIDRSSPTSGFSGDTWAVDRSSSGTAGGDGSGGRTRIGRFVEEIPREEAVGTPEVPKRSPLRDSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIX6</accession>
    <name>A0AAD8XIX6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_749191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368546.1">
        <property type="nucleotide sequence ID" value="XM_060513733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIX6"/>
    <dbReference type="GeneID" id="85397631"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="589" mass="67788" checksum="63FF1E283A87CA24" modified="2024-05-29" version="1">MSSSLDLVDGLAPLPTVRRGKKRIQGMSPQMATFSLGKRPRVKRSCAGKVRSGCITCKRRHIKCDETRPFCLKCTKSPRGPGVCEGNEFQQKQPDRQTQPRPIISKGTWRVWPAAVLREPGYESAFFSNPQEKVYFDFWQHLVANIYLFPNDIMVRVVPQLARREPAIKHAALAMAGMARALVPSLIRRSRKELHDNGPHYEFALQQYGRAIKLVRSSQPSSENMLWAIVCCVLFVTFECLHGDRNAALSHVNHAYKMMETYFNQRSMVEDSPVTDSIRAVCDDAAWVFQGLTMQAWSHNVLHSKDASQISWCCRGSKRTYAVEEMPIVFTDIHMARRWWRVVQHYTCHRCPIYTEMFVDGLSKEMLVGSYVRPALSPSHLDELATVLPEFLGHLRRWQNAFQGVYDTLRANQERDFHAYVDACNLRVQYLTLWTDVSSLSYKDIRVMIMLTPSFREMVQLSRIVLSAQQNCGGCTETFSMDNGPTLPLLIVACRCREDSVRREATELLGKYHRRDGLWDSRAFHSVALKNVAIEDENTAEGDDVEQWSRMSRREVRFSREGDVSGRMFRWQPDVKEWKHVEESLSMVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK22</accession>
    <name>A0AAD8XK22_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_569860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368864.1">
        <property type="nucleotide sequence ID" value="XM_060504238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK22"/>
    <dbReference type="GeneID" id="85388137"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="184"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="543"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="610"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="780"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1186"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="780"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="809"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="836"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1192"/>
            <end position="1203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1228" mass="134789" checksum="A75496F6735B5748" modified="2024-05-29" version="1">MISQNEQASRSPHTNKRPTSRNRQGVHGVPIVPTQAPRKESSTNASNPPSVPGTVAPSAFRLRPHENLQDKSTAALESNQLITYFPYPISSSGIPQSFPSPKTPQPSLTFSFGSDCAAALPSPAPTDQPSPPTVTSNQTSHQIRETFLQSPELGLDFAANNSNATTAWTSETRAQETPANVLAQNFSGAGSGNAVPDLSKPTPLSTNLHSTSRFTSFEPSEHPALLTPSITLSGNPPSSVSVSLPLVPDSQAAPSPTLNISSRLSSGQNSRPPAISSPLVAGDHTPQPPGERQDAYSHAVQPAGTSRDSLDSFVQVVMAKNLDSYISDRGGMAKLPEDGTTAPRVRLLKDAIEKADYFYIVLHQILCLWTLEKKAAQELLGLPPDVTDGALGIMQNVLRKNENMGHDTIFFFANFPASSASGLWHTEAYRNHTRDISRFLNNLHEQWNRILVPAMRPHSGRGYPILADELRYQLKLRSPILETIFFTVTRRHTGVPDGLIADQMNALFRQDSQNDQTQMSEEEQRVFQHSLISRYKILVSQSQQQQQQQQRRVAHQQQQQHPQQQHHQQQSHQHQQAHLQQQQDFARAAAIAQQQTAIGNLRRMSTNFSPAQARAPTPIQNSPTQGAENMTGMPNSFDQRAGPVPSQLRLLSQSLANQPLTPTGSPHYPSMQLPHVAQAPGQISPVLQAPPGGLSMSMPGLTSPTQAVAPRAPPLHPPGLFRDPSHYQTQPHNLGYQLLQQARDAEQRHTRSRQLDTAQNQAQAMTQLQATNVVPPRIQLHHHHQHHHSSPRPQGMQQGPSRGAAVRTSVMQQLPSPQPVASVSHASPRGLGITQGAPSTQMTRPPSASSRPTLPRELPRSEDQSQPVRFYQSTKELALGPIATPATNCVHRLAFVVPDEHCNKLCPTSNLVGDCVPVSEYFEGSLRYRLRLCELPINPAEPANISESVWAVAQSYWPEHIAIMVNENVVAVRRKQHNGQHLPVELTPYIQAGTNSITVSISPMPAAQKPNMMYFMAVEVVETLSHDNIVNMVLSQGTISADTTKQVIRSRLEPASSNGDDELVVVGSDLSIDLADPFSATIFKIPARGVGCTHMECFDLINWLQTRPVKPRCTAHGAGDACRVCNRGTEARPEPSLVDKWKCPLCDGDARPYSLRVDKFMEDVRKSLEAEGKLHTKTIYVRADGMWKAKEEEADDEEEEENAENGQPPAKRAKTRPSIPEPEIIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKK3</accession>
    <name>A0AAD8XKK3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_569250</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369130.1">
        <property type="nucleotide sequence ID" value="XM_060504170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKK3"/>
    <dbReference type="GeneID" id="85388069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000026">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF14">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="119"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="313"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="476" mass="52398" checksum="44B65CB7CE890D6B" modified="2024-05-29" version="1">MSAPRSPYRQSYRSSTDGRSRRRESNHPIVPPEKARTSNYSSRGDELPSHNGHLHRKPPPGSKVRVKPSGESGRRGFHPFKFLKISWKSSSRASLLCNFLWPFVPAAFAVRYTRPNDHVLIFILTYIAMIPCANMVGFAGQELSRKVSHVFGVLIETTFGSIVEIILFMVLLAGDQFTVIKAAILGSILATMLLCLGLCFIAGGMRRDEAEFSEVVSEAGSGLLLTAGVALAIPTLFANSLENQLTAEELGSKTRHISRIVSCLLVIAYAVYVYFQARTHHGIYDAIFEHDEQRDHDKRKDINKPKLTLTECLVALVIAITLVTFMAIYLVEQIAPIVERHNISDPFMGLILVPLVEKAAEHLTAVDEAWDNQMNFALSHVLGATLQTALFNAPLVVIVAWGLHKHMDLVFEVFDIGMLILAILTVGNFLRDQKSNYLEGFLSVTIYVAIAVAAFYYPNPPGHGGAAEGGSAEGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL97</accession>
    <name>A0AAD8XL97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_727424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369448.1">
        <property type="nucleotide sequence ID" value="XM_060512784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL97"/>
    <dbReference type="GeneID" id="85396682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="181" mass="20484" checksum="F6B7A5427755D695" modified="2024-05-29" version="1">MNSAFVGSDEQRGSFAYDKYSIHCVVPLHLELRDWYGVVGVEHLLPARYLVRSVPRDQSFHRRCPHTDMISLESTLACLIYRVLHQEYAKSNASLQKDDGLKICMKNQNNSGAGTKNAGSAFNFEIRNHSVRSTGIERDPEKTRQNGHEHFLHPYTETHSVHGPALFSSRPFVFNGQAKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB0</accession>
    <name>A0AAD8XLB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">3-dehydroquinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_716301</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369536.1">
        <property type="nucleotide sequence ID" value="XM_060511841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB0"/>
    <dbReference type="GeneID" id="85395739"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08199">
        <property type="entry name" value="EEVS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000015">
        <property type="entry name" value="3-dehydroquinate synthase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000018">
        <property type="entry name" value="Related to 2-epi-5-epi-valiolone synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050071">
        <property type="entry name" value="Dehydroquinate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035872">
        <property type="entry name" value="EEVS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622:SF3">
        <property type="entry name" value="2-EPI-5-EPI-VALIOLONE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43622">
        <property type="entry name" value="3-DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24621">
        <property type="entry name" value="DHQS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="7">
        <location>
            <begin position="86"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="8">
        <location>
            <begin position="196"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="55197" checksum="E4C81EF3CF245B75" modified="2024-05-29" version="1">MASDMKATVEPTKKGFSVCGYEKIEYDFEFLDGVFNKQNSQLADCYSRWKRCLAVMDLNIFNIYGKEMKEYFDHYNIELKIHKTMIGEKAKSMETLLSIVDSMTEFGVYRKEPVLVVGGGLVTDVAGFACAAYRRNTPFIRIPTTVIGLIDASVSIKVAVNYGNYKNRLGAYHAPTHTFLDFTFLRTLPTAQIRNGFAELIKISTCAHLETFDLLDRFCEELIKTGFGRTDGASKDVRDAADKINRNGIHEMLKLETPNLHEIMLDRVIAYGHTWSPLHELSPDVPLRHGHAISIDMAYSATLAHVLGKLSSDEHRRLLNLFSRAGLSMDHPLFDEDMLEKATSAILKTRDGKLRAAVPSPLGNCEFLNDISHEDMCAALKVHKDLMKEYPRQGAGLEAYVDASDTGYTINGSSVEDESRKHMNGVEQTVTRDDTISSNGSSTPEYGLSNGKNLDQDKATYAAAGFEPEVLKKLNAEEMKSSSTHGKVHVDEECC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLQ9</accession>
    <name>A0AAD8XLQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_716175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369736.1">
        <property type="nucleotide sequence ID" value="XM_060511827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLQ9"/>
    <dbReference type="GeneID" id="85395725"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="294" mass="34105" checksum="1B88DCBCC8346EA6" modified="2024-05-29" version="1">MRLLNVETRRLQEFFDEVPEYVILSHTWGSGEVTFQDLDRPDHTKKRGYIKIDGTCYLAARNGIKWVWVDTCCIDKTSSAELSEAINSMYRWYRDSQICYAYLEDFQQGDDPSSFDSQFSNSRWFTRGWTLQELLAPETVEFFDAVWKKLGTRSSLAPKIESITSIPTEFLKRNEDSPAIRSAKIAMRMSWAARRQTTRVEDIAYSLLGIFDVNIPLLYGEGERAFERLQIEIMKQGHDAVYRRFDTRTDKRERGEWGFDAAADRDDEAAFGRFDTNMGMDVRVQARAGQEPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM62</accession>
    <name>A0AAD8XM62_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_567443</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370050.1">
        <property type="nucleotide sequence ID" value="XM_060503955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM62"/>
    <dbReference type="GeneID" id="85387854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000005">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000241">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="320"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="643"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1729995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="721" mass="80702" checksum="06B92B078293DA7E" modified="2024-05-29" version="1">MDRQSVYSSHVFPATFDQNDDSRVQTQTQLENFILHFRHDNDYIYRNQLKENALLKKHYCDVDISDLINYNEELAHRLVTEPAEIIPLFEAALKKCTHRIVYPQLTKVDLPEHQLLLHSNAEDVSIRNLDSMTISRLVRVPGIVIGASVMSSKATSLSIQCRNCAHTANLPVLGGFTGVTLPRQCGRQRIPNDPTPKCPLDPYFVSHEKSKFVDQQIIKLQEAPDQVPVGELPRHVLISADRYLTNRVVPGSRCTVMGIFSIYQNKATKNSNTGGAVAIRTPYLRAVGIQTDMDQTARGQALFSDEEEQEFLEMSRRPDLYNIMADCIAPSIYGNVDIKKAILCLLLGGSKKILPDGMKLRGDINVLLLGDPGTAKSQLLKFVEKCAPIAIYTSGKGSSAAGLTASVQRDSSTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNARTSVLAAANPIFGRYDDMKTPGENIDFQTTILSRFDMIFIVKDEHTREKDERIAKHVMGIHMGGRGVEEQVESEIPVEKMKRYLSYCKSRMAPRLSPEAAEKLSSHFVSIRRQVHAAEMEANTRSSIPITVRQLEAIVRITESLAKLTLSPIATEEHVDEAIRLFLCSTMDAVNQGSNQGSKELNEEVSRLETELKRRLAVGWGTSLASLRREMVEQKGYSEQALNRTLMIMQRRDTIMFRNQGAQVYRNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMU9</accession>
    <name>A0AAD8XMU9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor IF-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_602456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370410.1">
        <property type="nucleotide sequence ID" value="XM_060507171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMU9"/>
    <dbReference type="GeneID" id="85391070"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070124">
        <property type="term" value="P:mitochondrial translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938:SF0">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="31550" checksum="3F21B484E67814E9" modified="2024-05-29" version="1">MRITRCLYNSRTALHRVFVSPFENIESISRRSALLSPVPRALPTILSPPLQGFARHAALIPRFKKKKPSPSGQVSGGDAAAKPGQLPQDRAISDREVMVVDENNKLTGPHNTRTFLRSLDPETQSLRMVSRPPPRPAPGQPPFAICRIVDKVAEKEKERALQKAKKDNARRLARVKELELNWAIAPHDMGHKMKQMKTFLEKGYKVEVIFAKKKNSRIATLEEAGALVQQVRDAVAEVAGAREYKEAEGQPRKVMRLHLESTAKPAAKAAPAQEASAADAAPEAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMY1</accession>
    <name>A0AAD8XMY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RWD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_747539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370375.1">
        <property type="nucleotide sequence ID" value="XM_060513452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMY1"/>
    <dbReference type="GeneID" id="85397350"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23822">
        <property type="entry name" value="RWD_ScYIH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="8">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="31426" checksum="A452B74F58B442FB" modified="2024-05-29" version="1">MSDDLRDEIEALNSIYGDDTLRHTPPDNYVLTLPGGPGASSLTLRFADSYPDVPPEILGTHSAGENAPRGAGARDLLLFREAVAAVYQPGAVCLFDAVEEFSRRVEEVSEAEPSGPPTKSHSPPPSTLTTRLDEEHGNQEADSLPSYMLEEPPWIISDPFVELKSVFLARAAAVTSPEQAASYVQHLIATDKKVRSASHNMTAWRIRGPNGTSFQDCDDDGETAAGGRLLHLMQLMDLWDVMVVVTRWYGGQKLGPRRFALINSTARDAFVKAGWAEEAGQGKKKGHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMY2</accession>
    <name>A0AAD8XMY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_602136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370318.1">
        <property type="nucleotide sequence ID" value="XM_060507148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMY2"/>
    <dbReference type="GeneID" id="85391047"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041981599" description="Secreted protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8804" checksum="16FD878CD7202DA4" modified="2024-05-29" version="1">MLETGMGSKFFLTLRVCACVCFAMLVERTTDAIIEMVRPVVPGTRIAAHCSLLDSVCEWKRYEGLEEEEHSPASKVPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN17</accession>
    <name>A0AAD8XN17_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_646827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370527.1">
        <property type="nucleotide sequence ID" value="XM_060510017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN17"/>
    <dbReference type="GeneID" id="85393916"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="243"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="448" mass="49205" checksum="53AD33AA6A27E2C9" modified="2024-05-29" version="1">MDYQNFQMNPDYYPISQSWDESLGMVVPNYTEDIDWMSEGVQNQLTEMASNLSHSISPQDSYGTVTSGVVQGAGVSAIESGLAGGMDASNSGGYHFQEQMSYSNGPALPPAPIPVPLGPFFAPEAPATGSVFAPEFDEDVSSNNNFPDDNMAGSTISNPAYYLHFGGNSTPVDDTEAGSSPFLAAEDYSSPSVDDNVVRDVLGPNNQDARVQKRGKGKGKAKAPRRAKETTPDRPARAVRAFSCKSCRRKKTKCDGSPGHACSKCQKGGTACEIDGKDGRTNKTILDKYESLRVALNAHLVRVAQICHYFCGYTSEPQDRCLVAAGAAKTLEVFRMRGITIEPWRLQDILWVKDFETHQLPEHRTRLGEIGKLVKEKTMILAKIIEMVTKGDSNLWDHGRRLIHGLFDRNTALEVLDKEIKAVFITDKQDFVYKVLANEVDEIIAQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNB0</accession>
    <name>A0AAD8XNB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370680.1">
        <property type="nucleotide sequence ID" value="XM_060513430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNB0"/>
    <dbReference type="GeneID" id="85397328"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="120" mass="13334" checksum="8CFF3430E93237E5" modified="2024-05-29" version="1">MSTQQKPLSWWKRHCTPPPAINRTPQCPCSACWNGNGEHWKTTVPQTTAPGYMSISSPATTNETRTMALRRETESDLTPLRREETSSTTNLSVYSQDSNASSDRASVTNVHRLALGKEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNU3</accession>
    <name>A0AAD8XNU3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_600402</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370786.1">
        <property type="nucleotide sequence ID" value="XM_060507033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNU3"/>
    <dbReference type="GeneID" id="85390932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000002">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GFAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="377"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="12">
        <location>
            <begin position="549"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="700" mass="77862" checksum="C104186FA8616833" modified="2024-05-29" version="1">MCGIFGYVNYLVEKDRQFILDTLVNGLSRLEYRGYDSAGLAVDGDKKNEVFAFKEVGKVAKLKELIAESKVDETKYFDSHAGIAHTRWATHGPPSRLNCHPHRSDPTWEFTVVHNGIITNYKELKTLLSAKGFKFETETDTECIAKLAKYLYDQHPDIGFTDLAKAVINELEGAYGLLIKSVHYPHEVIAARKGSPLVIGVKTQKRMKVDFVDVEYSEEGALSAEAASQNVALKKQQDNFLNPNTLLGAPDKSLLHRSQSRAFMTDDGMPMPTEFFLSSDPSAIVEHTKKVMYLEDDDIAHIHEGSLNIHRLKKADGSSNVRTIQTLELELQEIMKGKFDHFMQKEIFEQPESVVNTMRGRLDAANKTVTLGGLRSYISTIRRCRRIIFIACGTSYHSCMAVRGVFEELAEIPIAVELASDFLDRQAPVFRDDTCVFVSQSGETADSLMALRYCLERGALTVGIVNVVGSSISLLTHCGVHVNAGPEIGVASTKAYTSQFIAMVMFALSLSEDRASKQKRREEIMEGLAKIPEQIKDILTQDQSIKELCSKTFQNQKSLLLLGRGAQFSTALEGALKIKEISYLHCEAVMSGELKHGVLALVDENLPIIMILTRDDLFKKSLNAYQQVIARSGKPIVICNPGDEEFKTSEAEKIEIPKTVDALQGILNVVPLQLIAYWLAVMEGLNVDFPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNV2</accession>
    <name>A0AAD8XNV2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_646635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370792.1">
        <property type="nucleotide sequence ID" value="XM_060509989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNV2"/>
    <dbReference type="GeneID" id="85393888"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042241587" evidence="2">
        <location>
            <begin position="20"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="29"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="248" mass="24566" checksum="2709DE6A681B3704" modified="2024-05-29" version="1">MQFKISAAAFLAFAASALAQNANFDPVTKPTPNEQINAGTSYTIEWTAPDAFKDVTVSISLIGGATQNTQVPLQDIASGIPNSAGKYTWTIPSTLGKDAFYGLVVKSESNPTVDFQYSNPFHIIAGEGAASGTTTVVSSSPTATVTLSAASVSVTPTASASASASASVTKSESVIVNSTTALSTTAVPTPATLSAPASTITSVTRPATNSTGTATRSAIATVTGVAAGAQATAGVFAVLGGLAVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQF5</accession>
    <name>A0AAD8XQF5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_746105</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371725.1">
        <property type="nucleotide sequence ID" value="XM_060513206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQF5"/>
    <dbReference type="GeneID" id="85397104"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000464">
        <property type="entry name" value="GTP-binding protein ypt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="24002" checksum="7F65D7258F78440F" modified="2024-05-29" version="1">MAARGPGAPGARGMNTRFAQFKLVLLGESAVGKSSIVLRFVKDQFDSYRESTIGAAFLTQTISLDENTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQSASLDKAKAWVKELQRQANENIIIALAGNKLDLVTEQPDKRAVPTADAEAYAREAGLLFFETSAKTAENVKDLFTAIAKKLPLDQAGPRHARPGQRQGVSLQPETPGSNVSGPCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQL4</accession>
    <name>A0AAD8XQL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_725702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371696.1">
        <property type="nucleotide sequence ID" value="XM_060512740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQL4"/>
    <dbReference type="GeneID" id="85396638"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="29058" checksum="B348E2EE6D72E765" modified="2024-05-29" version="1">MCGIKQIVDQCRTCYGIISKEEIPTICHKRTWTLPETFGYAKAYCPDQGRVYLDKKPRINQCPRSESSLGTCSLSHGLDQIRSTSPWQNASVLNLPAEKESKSVAEKVKGFFGKCLSKVIPGVGKSSQSSSPWAALDQWEDICGDEDTNDKKKKKKKAASIPTVTRVGQLPLSEESDLASKDRMQRKSPALPDKALRRLCETRMRDANRAQSSVFAPNCNRRTLMIQVHYNLMAQAWSCDLQPKATTHDQNCASSRKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQQ2</accession>
    <name>A0AAD8XQQ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_725310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371758.1">
        <property type="nucleotide sequence ID" value="XM_060512732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQQ2"/>
    <dbReference type="GeneID" id="85396630"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32042" checksum="664CA650F311816E" modified="2024-05-29" version="1">MGWGSSSASLFTLSNSPPCVPMLDTRPARLPLPLLTLGPLALSLLQVDEKRLADDIELPHKVNLLQMSKILWVGTNGSSELGLLNDLCSRGRKTLEKYFNTGDSCWSIEDSSPIHGATLSSENHREYGNTVASMHGMACQGMEGRVLRPPYCVHYSVEGDGIRESSLDGTTPQVRTAVNLSWSALALCYDCHLSSVLSSSMMMIMWLRRTLIGLSRLDQQQADGWLLPKRQPANGTGVEVLRTFQVSPIVPALSVKPRSSRGVWIENKEGKAGKGEDDSDERGSLALTMEKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D067</accession>
    <name>A0AAD9D067_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_748644</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF2B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369260.1">
        <property type="nucleotide sequence ID" value="XM_060513647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D067"/>
    <dbReference type="GeneID" id="85397545"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000002">
        <property type="entry name" value="Translation initiation factor 2, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="311" mass="35403" checksum="3C2D190026FEF47E" modified="2024-05-29" version="1">MAEPNYSHFRYFENKYPEIDEFVMVNVKQIAEMGAYVKLLEYDNIDGMILLSELSRRRIRSIQKLIRVGRNEVVVVLRVDKEKGYIDLSKRRVSPEDIIKCEERYNKGKMVHSIMRHVAEKTLTPIEQLYETIAWPLNKKYGHAIDAFKLSITNAEVWNDATFPSEAVSEELKSYIAKRLTPQPTKVRADVEVTCFGYEGIDAVKNALRTAEARNDDQTQVKVRLVSPPLYVLTSTCLDKNLGITRLEEAIVEIRNSIEAAGGSLVVKMEPKAVTESDDAELQALMEKRERENAEVSGDESVSESDDNPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0G7</accession>
    <name>A0AAD9D0G7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_568660</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family. Class IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369276.1">
        <property type="nucleotide sequence ID" value="XM_060504101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0G7"/>
    <dbReference type="GeneID" id="85388000"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1072"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1097"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1123"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="14">
        <location>
            <begin position="412"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="122"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="546"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1729221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1228" mass="137730" checksum="E09F9A6394EA9BCB" modified="2024-05-29" version="1">MSLPERPAATSPFENRNAYRNSPSRRNRPDDVETGGYYPVGGRPQHQRGQSATSFPETISTPNINTENQPLSPTYDSPAPGPSTGDQAFTRKRSLIRPERHRIDKDHPNYYYRKHAANMNVLPSATGNDPIVEDMEGTTDVSGRSQTNDNFSDASPPRGVNSRQNSGEEKKGHSKTKAKRLSRHKSGKLTKDGKGKRHKNKQVEQIRPPSFWNVYCAIITFWCPNFMLKCCGMASKEQQRAWREKIGLISIILLIMGFVGFLTFGFTQVVCGTPPPRLQVNDVDSGYMIFHGTAYDLTRSRHPPADGVPMINRTHGANVLYDLPEKNGGKDGSFLFQNVNGRCKNLITLADNSDVPTNSNGDLAWYFPCTVFNQDGSSKPNLTIPYYLGYSCHTTQKSRDTFYLDLDGTADVYFTWNDIKNSSRNLIVYSGTVLDLDLLNWFNTSQVKVPDRFNELKDKTTAVNKAIRGRDVTRAFQASSDKQIAECFEEIIKVGSVDTDTVGCIASKVVLYVSLVLILAVVLTRFVLAVFFQWFISRTYAAAKTSQTKDKRKRNQQIEDWSEDIYRAPPRLPGDIGSSVNGSSDRTSKRQSTFLPTTSRFSAVYGAGAAPQAGGRRMPTTMASSGAGSNMMHSNAMYRQGNDSRTSFLRSDPYTSNVPSTEGPGPAGFIHEAVVPQPPADWMPFGYPLAHTMCLVTAYSEGHLGIRTTLDSIAMTDYPNSHKVIVIICDGIIKGKGESMSTPDYCLAMMKDHTILPEEVEPFSYVAVASGSKRHNMAKIYSGFYDYGNESAIPLEKQQRVPVLLVVKCGTPDEATKSKPGNRGKRDSQIILMSFLQKVMFDERMTELEYEMFNGLWKVTGISPDFYEIVLMVDADTKVFPDSLTHMVSAMVKDPEIMGLCGETKIANKRDSWVSAIQVFEYFISHHLSKSFESVFGGVTCLPGCFCMYRIKAPKGAQDYWVPILANPDIVEHYSENVVDTLHKKNLLLLGEDRYLTTLMLRTFPKRKQVFVPQAVCKTTVPDTFAVLLSQRRRWINSTIHNLMELVLVRDLCGTFCFSMQFVIFIELMGTLVLPAAIAFTFYVVVISIVNSPPQIIPLVLLALILGLPAVLIVLTAHSWSYVVWMLIYLCSLPLWNFVLPTYAFWKFDDFSWGDTRKTAGEKTKKAGLEYEGEFDSSKITMKRWAEFERERRTRNNYWGSKENVVGGGNTWSAPLGHQYQDEYYSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0H5</accession>
    <name>A0AAD9D0H5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase type 1 complex subunit Hex2/Reg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568677</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369321.1">
        <property type="nucleotide sequence ID" value="XM_060504105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0H5"/>
    <dbReference type="GeneID" id="85388004"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="63785" checksum="5CA5F9A2C161A1DF" modified="2024-05-29" version="1">MAVVLSSEENTYFSSSSLRRSHSQPKFVTKQASFHSAPAPSHISDVFADAKVYPDSAPSSAPSSPRTIHAESTDLSCSSTPASNVSIASDCDDTLELAVHANDHFVIPTYGESGYFDQVEDLEAPTSPRTGDSYTVSPVDNDTDGNTSRPNTPEFILDVEHAEDDTAVRAQPSRHVDYLSHNWKEEDIWSSWKFIVSRRSEYSNAARLENASWRTWMKAKNHLKTVSPETLNWLKDCDVTWLYGPLQTGPNTLNPITTDPNSARLTKNNSFVNKKPILKKRSMSEVMLQRSLSASSLLKQAAAAVQAQEKDGRRRLARPTLERATTDYVTFPFSSRRLSRESSNLCPSSTSSGIISPCSEKKHIHFNEQVSQCIAVDIKGDDDDDDADTERYDNSDSDEGAIMMKRSRTKKKAPLLRRKSSKAAAAVEGKTIAMLPSTTLKYREDTPEPQETAMKHSTSYRSPIMSPSSSQETLRPSKGSGKFFFDDDDDEEEEAVSMGWQSPTKADDKSTGLQRSSSTNSLNAEPAGMRRTSSGMFMPYEEGESSSNEGIIGRVIDTVNTARDIAHVIWNVGWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D118</accession>
    <name>A0AAD9D118_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_603418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370232.1">
        <property type="nucleotide sequence ID" value="XM_060507226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D118"/>
    <dbReference type="GeneID" id="85391125"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="69" mass="7632" checksum="F84E26B231AF7D2F" modified="2024-05-29" version="1">MLQKPSPSKKCPPFRPKYADQHVQDGINPCQSHRPGEPAKPGQDSGYLASQPRRSCPQPQNPPVPSWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D159</accession>
    <name>A0AAD9D159_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_605655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369636.1">
        <property type="nucleotide sequence ID" value="XM_060507341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D159"/>
    <dbReference type="GeneID" id="85391240"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="47"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="818" mass="89850" checksum="DE26DCF26CF5E58C" modified="2024-05-29" version="1">MLVFRASVPRRGHVGRFPGCSFSAGIVSFRRSIHMPSVQSKHRSPIKDIRNIGIIAHVDAGKTTTTERMLYYSGVTRRVGDVDAGNTVTDFLDLERERGITIQSAAITFNWPLHEECAPGTTPKTINLIDTPGHQDFRFEVDRCLPVLDGAVCIIDSVKGVEAHTERVWASAHDHKIPRIVFVNKLDRDGASFRKSVLEIGSRLNGWPLVCQIPWWEGDQFVGIIDVIDRVGYRWKAEKQKTKYEFAELQEVLKGNYLLDEIETARERLIEGLAEWDESIMDLFADDPSKITGKMLKDSVRSAIRSGDGNVIPVLAGASFRHIGVEPLMDAIVDYLPSPDERPDLEIRAGPAKHNLTALLDQNSSKKPGQQRVAAVASVFKVYNHPKEGILSFVRVYFGELHKNSSTWNTHNQLAERPFGLLQISAEKTEDVQHLATGQIGAIKGLKKARTGDTLLATVAQKQIPDALKHIQIRPPEIPPPVAFLAIDPHGPTASKELEIALENASREDPSLRWSRDEKTEQFILQGMGKLHLDIAVYNLKQNPKVQADFGPIEVDYKECITSSIGPHHVTFDRVVASKSGKVSCTATLEPLEDHHRQAALEPTIERDGNIIHVIIDLPEEGNIAFDPEEARQQLINGAVAAVARGPRRGSPVQGCHITITVDAAAVESPSGGHFAGAASRAVREALREAHITKGAVGVLEPVMLLHISCPEAAAGLVQHDISSGAGGHVLEVNDKSAESSSHIDVSSIYAPPDPYEIVASLRGKKSLARTVEIVAKVPFKEVLNFDEQLRGKTGGRHSMTMAFDSFDRVVGQREKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D187</accession>
    <name>A0AAD9D187_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_567877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369681.1">
        <property type="nucleotide sequence ID" value="XM_060504001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D187"/>
    <dbReference type="GeneID" id="85387900"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="496" mass="55055" checksum="8513A987E28E91AC" modified="2024-05-29" version="1">MTNTSDPETVEVMPEIRAQDQPIASSRRVTVRLGDDGPNSTRSDIRISHGSKKDALSIQLNRTIRVPDNRDTNSLPPGLGTFPLFKIRDYAHNMPLDMAKKGGIFFPMYQREAMWVNFSAQAPFAIKIYVGGVNAVSGLPMTENEKTLEKRVRMLNSGKQIQDYMVVPDQNWLDGIVSEDGKIRQFVAQPKGSGFSVEAQVTGEENIGGIQIEVIPIKKNLPTEFDVRYENKEHKVITRTFNVVEKGLTSESTWLDVKKLICDEFDIAVDQQRLSDHGNHMGFDKYRIDFSDDTKLGDTYFPPNFSTVNVVHDTPMRGRMRMMGGLKSMAVPGGGPEMMMCAASVSSPMAAPPPAVEEMGLAAGGLITQTIEEDKYPADVWDVEASVMMNLQILSVESFCAVTGQPAPDTPVNAQSYANHGYPFFEIWGEEKTGIKGDFSEVKSVAQIEAERAAAAGEEYKEEESVPVRIMQLGPFRSTFRPVEVLKKELEGLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D190</accession>
    <name>A0AAD9D190_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTP cyclohydrolase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_567792</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369860.1">
        <property type="nucleotide sequence ID" value="XM_060503987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D190"/>
    <dbReference type="GeneID" id="85387886"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="7">
        <location>
            <begin position="104"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="6">
        <location>
            <begin position="334"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="56572" checksum="3CF87026004FB9B1" modified="2024-05-29" version="1">MSDPTVDNGPLAEVISSLKSIQQTQSDLVAAVDLLNQRYQQLPVDPDAATLGPEPSLGEVPERSRTPEPSDVVGDSAKSSASDLTLQAPAVPSSPSQRSGLTSRIILTTYPKQIGINPLPMNWGESDPHRRGPVVVSRSSTTIGRRNGPGGSYSIYYALAVASKQLNLEHRPDFTNTEPAAKIGPFPQWGDPKKIVAMDPWGHLSPWLFKDTIEKHNVDIRPTIAITKAHMKLPELEESVKSGRLVPDGKVCLNELGELAVTKFAVEPVWYLPGVAERFGIDEGALRRSLFEHTGGSYPELITRNDIKVFLPPIGGLTVYCFGDPAKMSDESVRLALRIHDECNGSDVFGSDICTCRPYLIFGIEEAVKEAQNGGSGVVIYFRKEGRALGEVTKYLVYNARKRGEDRASDYFKRTENIAGVKDMRFQALMPDILHWLGIRKIDRMLSMSNMKHDAIVGQGIPIHERVELPDEWIPADSRVEIDAKITAGYFTAGKRMTEEELRAVQGRMWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2J5</accession>
    <name>A0AAD9D2J5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Emp24/gp25L/p24 family/GOLD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_600678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370850.1">
        <property type="nucleotide sequence ID" value="XM_060507047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2J5"/>
    <dbReference type="GeneID" id="85390946"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042096300" evidence="10">
        <location>
            <begin position="22"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="8">
        <location>
            <begin position="45"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1730795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="23349" checksum="8B2E09543D9213CA" modified="2024-05-29" version="1">MFFPSVAKLLLAAGFVHSALAHNIQLPAHGRECFHESLHRDDKMTVTFQVGDREFGSAGNLDIDFWITNPQGQYETFDKSVSNGDFSFDAKHDGKYTYCFGNEHWGAHSKEVSFNVHGIVYVSETDVPADPLEVEVRHLSELLAQVKDEQSYIVLRERTHRNTAESTNSRVKWWNLFVIGLVVGESVFQVWWLRRFFEVKRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2N9</accession>
    <name>A0AAD9D2N9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_291529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371029.1">
        <property type="nucleotide sequence ID" value="XM_060502193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2N9"/>
    <dbReference type="GeneID" id="85386092"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042252348" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17369" checksum="7216E5A71377CF94" modified="2024-05-29" version="1">MPAGALFPLVSLLSRLDVSTTAPRHWPGIQEQSTHALQCGADVRYGYGYLRSWGQPRRGKVTSSSSRPLFLNVSVGAQSVQCYIAASRHGRWSLVHSAKIRRSKRSTGIFPVLPARQRAVRIPAMRRRPPALRIAQRILPNVRKDWRLASRYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D317</accession>
    <name>A0AAD9D317_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_759599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372002.1">
        <property type="nucleotide sequence ID" value="XM_060515146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D317"/>
    <dbReference type="GeneID" id="85399044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="40430" checksum="6F35414F43D475CA" modified="2024-05-29" version="1" fragment="single">LSFRSFLFVTHTVPHLLSRSSRIQRQAISSLSLLNSPHPAKTFLPSITAHQPANMDPNKINWKDAFLFFYWDLRDEDSDSPLAGKAKYDNFVMEFLKGERLPLNTLSRPKSWNHLLWHLMRSSLYQTGKYLQHFSARLNLGENGSKSNYNWLYDSPSETEEPWVNWMEFLDIYSEQVEFDERREYVNRISWVLDYLEERAYANIHCNLTMNEAWASNPYLLEFGDSQGLRLDWAVSLPITGASSYELGLPFILDQGFTIKHEVASNAIRLHSDRDRLGNRILLSAAHFYYTRILRWAEYMSDQGRVSSIGNFFLRGSEIRHWSKPYKAADRLRITKELWESIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3E4</accession>
    <name>A0AAD9D3E4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_646075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371629.1">
        <property type="nucleotide sequence ID" value="XM_060509917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3E4"/>
    <dbReference type="GeneID" id="85393816"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="90"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="265" mass="29377" checksum="859777D5716DE8D0" modified="2024-05-29" version="1">MISCAQLFSFLLSSGLVVLFPALFPLAEFQRKQSPAHGPVATLTMKPQRELLPAGPTAASSASSERETTPQSATGTTSSAPRRRPQTKIACTSCRRRKSKCDGQRPVCSLCAGMGRTRCEYDAGPDVTRFAALKTKHEELQRRLSLFEELFRLLSIRSEPESVEIIRRVRTLNIETDLDDLVKFIKNADLLIQLASAQAEPPTSETTTNHQDPPDEDLSSLIELLYSTLSPMASLSSVELADPKISENRRFPNSTQRLGWPFLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4N4</accession>
    <name>A0AAD8U4N4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_229485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000278">
        <property type="protein sequence ID" value="KAK1703566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357317.1">
        <property type="nucleotide sequence ID" value="XM_060501797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4N4"/>
    <dbReference type="GeneID" id="85385696"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF215">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1703566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="433" mass="47564" checksum="70E7A005C6C47400" modified="2024-05-29" version="1">MLNIAIIGGGIAGLTAAIALRRAGHSVTLYEKTSLNNEIGAAINVQTNASRPLVALGMDPVRARFVMATGSRLMRGDTLEVTHELNLGAIANSYGSPWYFAHRVDLHEELKRMVIAADGGPPVTFKLRSEVTNYNPDAASFTLRNGTVVSADLVVVADGIHSGGVEAILGSPNPAFPAAQDNFCYRFLIPMDAVLLDPITSKLFKDGAGGFRIFLGNGKRIVTYPCRDGEVLNCIAIFHNEFDPSSREDWHNSVDQSHLLRLFENFHPSVLALLRKANEVKQWPLLYRAPIPRWSKGCTVLIGDAAHPMLPHQGQGGAQGIEDGVALGVCLSNTTSKDDVIERLKVFERIRRNRASVVTIFSNAGQDEAEKIKEAASEFIPVERIPTNPSGFYDFHFSYDIMEDSAEHMRKLDPNFRLPEAFLRNEPGNRAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U631</accession>
    <name>A0AAD8U631_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_642630</name>
        <name evidence="3" type="ORF">BDZ83DRAFT_642632</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000204">
        <property type="protein sequence ID" value="KAK1707763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAHMHS010000204">
        <property type="protein sequence ID" value="KAK1707764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358141.1">
        <property type="nucleotide sequence ID" value="XM_060509628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U631"/>
    <dbReference type="GeneID" id="85393527"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="98" mass="11055" checksum="517B9376FCE52190" modified="2024-05-29" version="1">MFRRSTFELRTVNLPSDRRKTSRKKTPPRDSPRSFPCRKYFTRATKAPGHEYASQNQCRLCLAMREGCHDGFNGVDTGAACRDCAKTGHTCLSKAQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6E4</accession>
    <name>A0AAD8U6E4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_645168</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000298">
        <property type="protein sequence ID" value="KAK1702878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357198.1">
        <property type="nucleotide sequence ID" value="XM_060509819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6E4"/>
    <dbReference type="GeneID" id="85393718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133646" evidence="4">
        <location>
            <begin position="16"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="645"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="663"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1702878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="959" mass="105926" checksum="97BFEE9691C85CFE" modified="2024-05-29" version="1">MKLVYFLSWIAVAAPHPSLDKATRVDVLHNVTVNVAAPLGIDATPSSQQIECPILCANHTNTNTWTEYGSIDHLRRCQEPMLIAPLFPDALANLTSTTTVYGCSLNSSRPVIDWTKESLAKSSQFSIRQPDGMYSASCESTGQEVESKVMVVRGNDGNDNFSRLDLMLLGQSVEKTLADPSNCPTKTLFAQSRSMIVSIYSGGSLAKSTITSAWNAISYLPILGHPTQMLVEICDDSRGPERILGIAIDIVENRELVEDFTLGWSQGKCFAGPKNATVLPGVKVHEISDPSLRLSRPQLPRPQIPRPRPSRPQPPRPQPPRSQPKRPGPPQHQPKRPRPPQHQPPHPEPTFQRRELQRCISGEDRTLNTGNLCEFSCEYGFCLESLCECTARGIPSQVPPEKEVDVVAWDDTNTDLNILCKFACKYDHCPQDICTSRIDGPDTSDIDIVGTDHEDPLDYVRRAKKSNAKNCNIYKESRHWDFQKTSCDSICKPEIDQAKKEGKMYNAFCLGFWPIDKPIPWQKMGPDTTIAGGTCECNNPLVNEFADIVLDGMPQMAQISCYIMMSTLKLVLEIGVEFIPVVGKPISAGLEIANTAAQMAAYLYPKEEDPEGAFSWWLQPCGGTNLVPEDIKKVYDILSNSPAGRDRFEKKKKSDNLKQGSGKKGDDNNPTDRKIQKGRKCRVPPAKSTMRLGAAKNILRIQSCVNDATRKNDLVVTSVVYAPNAKPTVVERECSQKWSQACFHYSSAIKVNPQWATLTCPPEAAATAWRLDAEAVPAFQKQHKGDRWLDEVKSNPNKVDCDKDEYPPAYLIGPQDPARLNSGKSAQGQLIRLIPGGMNRGAGHMWKGICLGAAIEDMKDSEFKAKVDADPNKKTVIQGGVTRTQAAITATIRPEFTINKWGHAANPPANDGLELNTCWPNNIAAGDPGFALLTFDPYYNTHPRLYNYSLPYVKGSNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8K4</accession>
    <name>A0AAD8U8K4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_758238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000212">
        <property type="protein sequence ID" value="KAK1707330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358018.1">
        <property type="nucleotide sequence ID" value="XM_060515001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8K4"/>
    <dbReference type="GeneID" id="85398899"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="285" mass="31420" checksum="A4A9437D3D68BAA6" modified="2024-05-29" version="1">MAGPLSFAASVAGFISSASNAQNALRTALSRSRESVSAQESLRRSDASMTMLKVIYLDLDPGTLAGRIGAAPATQMHRQIGEIRLAELNISLDKKLQKEYASHVGESAERLEKALQRLRDIEQTFMLRRIEAIVLKSEELQLKRDAENTKTEQAVAEIGQALSLLQSHMATDGRILDKGIQQALTNIGQRMSEISLLFVEGETSDRTIDELRAAIQSTIGRSQGFDRNQVVFPFVIPMQEVEDVVARVILDTGVQDNWINTNTGTSEWSVFNRITTSSLMAADVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U996</accession>
    <name>A0AAD8U996_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_636910</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359877.1">
        <property type="nucleotide sequence ID" value="XM_060509279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U996"/>
    <dbReference type="GeneID" id="85393178"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="715"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1713824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="779" mass="87058" checksum="5BD02460FE35DFDD" modified="2024-05-29" version="1">MADEKNHSVDVTQAATDLENFQRDHQWDPNLPQDKADMVKKALQDGDSEEIIAADAILTEDSPYEEVRAAVRNTDGGEVANTVRAWILGMIFVTIGSGLNMFLSMRSPAINFPSIIVQLLVYPIGCLWARVMPMKVFNTFGVQWTFNTGPFTIKEHVVITLMSNVSIGYAYSTDALLALQGKPFYDINLGWGFQLLFTLSSQLIGIGLAGLCRRFLVWPAAMIWPNQFANTSLFYALHDKSKSDGTHSNGWIISRYRYFFYVLAAMFCYYWIPGVLWQGLSVFAFVTWIKPNNIVVNQLFGGFTGLSLIPITFDWTYVSAYLGDPLLSPTHTHVNVLIGLFTFVIIPTIGIAYSGALFADYLPINTSQTYDNTQSSYNVSKILGPGYTFSEEKYKQYSPLFLPPTFALNYGLSFAALTAAIVHCGFFHGKEIWYRLKAARNQEADIHLKLAKKYVDAPEWWYAVLLLFAIGLGLATAEGYDSQLPWWAFFVANFLAMIFVIPTCTILAISNLGLALNVLSPFLAGFMIPGKPIGVMIFKVYSTITLGQAQTYSGDLKMAHYMKIPPRVTFWCQVVATIWAVFVQIAVMNWTLGNIENCCALTQHAHFTCPNGRAFFSSSIVWGVIGPRRMFGAGSIYHNFNYFWLIGACLPIVFYVLAKVLNLKFAKVLHAPVMLGAMGWLPPATPLSFSSWAIVGLIFNHGVRKRFHGWWKTYNYITAAALDAGLIISTIVIFFAITLPNVTIPQWWGNVDVYNTLDSTYGAILKTVGENETFGPTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9G4</accession>
    <name>A0AAD8U9G4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_683980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000184">
        <property type="protein sequence ID" value="KAK1709394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358528.1">
        <property type="nucleotide sequence ID" value="XM_060511233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9G4"/>
    <dbReference type="GeneID" id="85395132"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009367" evidence="5">
        <location>
            <begin position="16"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="551"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="594"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="123"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="615" mass="64542" checksum="16EC8538B47FC83F" modified="2024-05-29" version="1">MAVAVAAMPLLGALARPSSPSACLKRQNDTNLLPSYDYIVVGAGASGLTVANRLSEDPSVTVLVIEAGDLDAGEDYVKIPGLAGGAVGTKYDWNTTYAANDALGGRSVSIPQGRVVGGSTKLNRMVFDRGSKSDYDRWESLGATGWNWDSLLPYFKKNEKFTPPKADIVSEWGVQVDDAAHGSDGLMQVTYSPFFWPTTKFMIDAVKELGITVAKDQANGSPIGGYFCPHNQDPTSSTRSSAREAYYDNFTGRKNLHLLTGRQVTKVVTSGSGDAVKATGVEFAASKGAQAQTATAAKEVILAAGALHSPQILQVSGIGDPALHTSINVPTVVDLPAVGQNLHDHVMLTVVNTINTTLPVSSLLQSNATFAAEARAQYDSQKNGPLSSPTGDFLAFLPLSTYSKAVDTLSSEASAQDGTTFLPSGAPAEVVKGYQAQQKVLNERLTATDSALLELIWADGVVVLGLQHPYSRGSLKAASSSTFDAPTADSAFLKNPLDVSFLVEGVKFARTIAGTEAVKPLQPFEVVPGANVTTDAAITDFVRQQSGTLFHPVGTCKLGAREEGGVVDASLKVYGISGLRVVDASIMPLVPATHIMTTVYAVAEKAADIIKGKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA24</accession>
    <name>A0AAD8UA24_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_131059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358843.1">
        <property type="nucleotide sequence ID" value="XM_060501215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA24"/>
    <dbReference type="GeneID" id="85385114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089:SF1">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="167" mass="18180" checksum="FE1DB6EE0F145B63" modified="2024-05-29" version="1">MYSNRSHPLLEQVPLTVSPFISLPAATTLSYNYKAMPSALPPSATAGDTTANKPKYVISQSGHAAHPDDIIASCRALQAHITKMQEDAERDLRDLETRIKERELAEKRRVAPGWLDSEARILEPEKVGGPSEEEDGHQTSAVAGTSEMPLNDQGAELDRVFGGLSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB87</accession>
    <name>A0AAD8UB87_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP-ribosylation factor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_755816</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360841.1">
        <property type="nucleotide sequence ID" value="XM_060514670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB87"/>
    <dbReference type="GeneID" id="85398568"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000832">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1717354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="186" mass="20671" checksum="A86AF415562F67E1" modified="2024-05-29" version="1">MGGQLSKMMGKIFGSKEMRLLMLGLDAAGKTTILYKLKLGQDVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYFSGTQGLIFVIDSSDRARIEEAKSELHRIINDREMKDSLLLVFANKQDVNGAMKPQEVTEALNLSKLKDKVWYVVPSCATTGEGLLEGLAWLSNNVKAPPAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBA5</accession>
    <name>A0AAD8UBA5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_633897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360871.1">
        <property type="nucleotide sequence ID" value="XM_060509058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBA5"/>
    <dbReference type="GeneID" id="85392957"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000282">
        <property type="entry name" value="Glyoxylate reductase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF269">
        <property type="entry name" value="HYPOTHETICAL D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="60"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="124"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1717384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="339" mass="36256" checksum="5875F646EDCBCC80" modified="2024-05-29" version="1">MSKPIVLQLGQIEHAHDTWASLADVAQIIKPKATNRAEFLEECKSGALDGVKAIYRTFASVHITGRIDAELVAALPSSVGFICHNGAGYDQIDIPACTSRSPTPILVSNTPTAVDDATADIAIFLILGALRNLNASILSIRDGKWKGQPPPPLGRDPQGKILGILGMGGIGRNMAKKARAFGMEVRYFNRARLEGHLEDECGASYVDFETLLRESDVISLNLPLNAHTRHIISTPQFALMKPGVVIVNTARGAVIDEAALVAALDSGKVASAGLDVFENEPEVHPGLLANPNVLIVPHMGTWTLETSVKMEKWAIGNVRRAVTEGKLDSVVVEQKGLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBT2</accession>
    <name>A0AAD8UBT2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EC5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_723117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360137.1">
        <property type="nucleotide sequence ID" value="XM_060512526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBT2"/>
    <dbReference type="GeneID" id="85396424"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22778">
        <property type="entry name" value="DPBB_CEPL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922279" evidence="4">
        <location>
            <begin position="19"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1714994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="14085" checksum="73E9D5E756CBCCDD" modified="2024-05-29" version="1">MQFSNLVTILSSVAAAAAVSVSYDTGYDDGSRSLTAVSCSDGANGLITKYGWQNQGQVAKFPYIGGADAIAGWNSPSCGTCWQLTYNGKSINVLAIDHAGSGFNLALGAMNDLTNGQAAQLGRIDAQATQVGLNACGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBX1</accession>
    <name>A0AAD8UBX1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000175">
        <property type="protein sequence ID" value="KAK1710017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358713.1">
        <property type="nucleotide sequence ID" value="XM_060509519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBX1"/>
    <dbReference type="GeneID" id="85393418"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="563" mass="63535" checksum="AF0371BD80185CF8" modified="2024-05-29" version="1">MQFIPQVDLGFSRTPSIFIFCQVFTEMSGLEKLKKFHPPAFLDDFEGEQLERWSKTVDGWFGDEIAGRLAGRKILTQFFNPLHFAFDSSLPPVPITWVGFPLNVRIKQPTDDARWAYAEDPDNQRAPPGRLDPEILKFHRKNEQTGEDEVVEVSRQREDRWVMDEYLEWSTKKVDGDVQTVSFTCEGPEYWEELAKYNPILTETPIKNPATQEYERNNKILNIYKKLNPDFAHEIKGDHLVDDEGNYNIYNRWNGHTNTGTIAHLIQINNSLSAEIDIAAQATVTRSDLVYGEPITNMLTLCGDGSAYGNPSRNSDPTIGAAVNEVCRLARDTVCPIPVTISVKDPVALYMYDADFSSFLLDRTGKRRGNVREMVQVPEGVFDWCDRGDITRNMGLHLRVSIPKGLKTDDDTRDLTLSDLFDQNNGGRYVHYGSQFADYIFMSVSGVVGPKPEPQNDGEAWPGKPQPALTYTEPYLQKPFIEPKVLGGPDLFKKMGEDDADETTFDRKGDSRVEFNAVVTTSDLEAMDLRVEAKDGPSGYMGMPEPGPPNGPDYQSITPKVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDH0</accession>
    <name>A0AAD8UDH0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_638562</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359389.1">
        <property type="nucleotide sequence ID" value="XM_060509370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDH0"/>
    <dbReference type="GeneID" id="85393269"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF45">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1712271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="35823" checksum="DD278735A7E8C320" modified="2024-05-29" version="1">MSSSTVSDMMAKYGPEVQKVSADTPLDDIIYLLKRDGGVFVRDLVPVADVDKAHDECRERLENDVEWNGSFFPKETQRAPALLALSPTYAKTQVMNPVYQKVCEHFLTTRSWFWWGNEKKESVSKPYVHSCTAMSIGPGGKAQPLHRDDYISHNYHQEVSEWDDERDKSRETAVGLFVAGCKVTKENGGTQFIPRSHLWGTDRHMPPQVEECIYAEMEKGDAFIMLASAYHAGGHNTTKNERRLMFATFSIRGYLRQEENQFLSVPQDVAKMLDQPIQEFMGYSMSDPACGYVDQMDPIFVLRPELKGDGRPSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDI8</accession>
    <name>A0AAD8UDI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_722543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360913.1">
        <property type="nucleotide sequence ID" value="XM_060512481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDI8"/>
    <dbReference type="GeneID" id="85396379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="59745" checksum="CEAEFC2E43D1D1BF" modified="2024-05-29" version="1">MFAPMPRRNVDGPVSHAKWPTVDAFRSTSTASPWDVDDSTAQTVSKLNCVFGFRPPNVYAKQPPRSSPDEVSRYSPDIQHLRLDQTPELRQDTPSDVRTRTSSFGPETPPTKFDSYFAPEPAVQPPTPSRSVHGHLRSHSDSCSFTSLWPDSQGQNRFGGEATSNHGIDTKQHGYLDAAASRLGDNSQHRRQSREAASPHQNYTVTLTRNNRAVTLILQQGRPIKQGQATITCYRQTSLALGGPYAEFFKASEALVLLQHMVNASSMSYVPFSKRERSELMLRMRTSPDAMILGEPCSNARAWTSFFSTELGAGRAWEVGTVIFPWKVLERLMSSLNSEFARKRRVQSRAAAAFNRREAEEHGGPRGGRGGAVYQHSYSHSYDSRPVSLNLAGTEHGNLETAAGDRSSVASGSPPPRTPTEILPPKLQLLPEQRTRQSPPPPPPQAAVTAAQIRTRRRQHSEPAVRRLSLTPPRISLLKSNNLRRLHASSTPTRLEFYDSIRAWPASSHRARVRLPPCSRFLEMVEDQGADSHNPIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDQ5</accession>
    <name>A0AAD8UDQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="3">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-methylcrotonyl-CoA carboxylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_586071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000103">
        <property type="protein sequence ID" value="KAK1718127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361127.1">
        <property type="nucleotide sequence ID" value="XM_060505911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDQ5"/>
    <dbReference type="GeneID" id="85389810"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905202">
        <property type="term" value="C:methylcrotonoyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000004">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000007">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF13">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="7">
        <location>
            <begin position="67"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="8">
        <location>
            <begin position="334"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="61507" checksum="73CB552182872C9E" modified="2024-05-29" version="1">MSFSRSSRDVLLLSRQLTRPGFRAPRLPRSARTVATFTAPHQASAISRIQTNVDPTSEEYKENEKHMGEVMKKMQDLTRKVHLGGSAKAREKHLARKKMLPRDRVTALIDPGTTFLELSPLAAHELYPEADVPAGGIITGVGVVEGVTCVIVANDSTVKGGTYYPITVKKHLRAQAVAQENKLPCIYMVDSGGANLPHQADVFPDRDHFGRIFYNQARMSSMGIPQISVVMGPCTAGGAYVPAMSDESIIVENQGHIFLAGPPLVKAATGEVISAEELGGGKMHSSVSGVTDYLAVDDAHAITLARRSISNLNWPTKSPSTAAPVKDYAEPLYSPDELLGIASTNLRKPLPIKEVIARIVDGSEFSEFKRDFGSTLVTGFAHIHGYKVGIVANDGILFAESSVKGAHFIELCAQRGIPLVFLQNISGFMVGSAAERGGIAKHGAKLVTAVACADVPKFTVVVGGSYGAGNYGMCGRAYSPRFLWMWPNSRIGVMGGEQLAAVMETVGKADPELKERIERESDATYSSARLWDDGIIPPQHTRQYLGLGLRAAMSGRNEVKAGDTKFGVFRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDX5</accession>
    <name>A0AAD8UDX5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_78928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359793.1">
        <property type="nucleotide sequence ID" value="XM_060515693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDX5"/>
    <dbReference type="GeneID" id="85399591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042138040" evidence="2">
        <location>
            <begin position="21"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="39281" checksum="ACA8F81A090032C6" modified="2024-05-29" version="1">MVLAVSIVLALILFLLCGWPRRFDRLNAYKGCTARPKNDELGLKKKHDSGNAVQCARQLIYLVMEGAWGQQDPRAIKKTPLASPLPSVVTYHSLEYVEIHTNVRPGRPEAGFRLHMNRRSRSRSSLRGRLALANKSTTSTVLDVRRVQAEPYHYLRRPHSRSAGPQAVTPLAPGGLELLLLFADRRIRGSSSIFVPEYCICRFQIASLARCVVNPRRDRGPRRRPVPRPRNRAAENPGSFLSPISIDKQPRGRREGERDGLYLARQKEGSQGSGVACTLYFQCPFRGPPCPPPTAFVRFRETEPRRGNRRPFSRRRSHKRGERPCQRLCRRSPAQRETRSLIVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE32</accession>
    <name>A0AAD8UE32_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_734584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359856.1">
        <property type="nucleotide sequence ID" value="XM_060512948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE32"/>
    <dbReference type="GeneID" id="85396846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43240" checksum="E91FD35365F174A4" modified="2024-05-29" version="1">MANTHEQQQDSHLLHRPTWRTSNGLGCLRSRFQNLPAEVLLVIIEQFLQPEAKRGNLQDLGNGGPSPSELQRLGLPVLPSPTPNTAQAQKPDEAQKPTMPDLAELFYLGLLNDRLRELIPPMLESHARSNSSRSTNASMSPTSQTDPSGLYSYILIFSTIRGLREGIIAALDRGADINANDGIEKSLAVNRMTDNKPTGSCLTALHWAAFNRDTAMLRLLLDRGADVRRTAVRTTYSSMDAHNPIRAQGFRPHLLLGPGDRLEDNAKTLVNALGFALQANYRLLPDGMTEQQRQAFVADRDMRDEEAVRILVEAGCPAFVMEHREREFNDACELERWGVARDILANTEWRRRCAERDDDSSRLSLVRVVRGRNPSRRVMGCNANEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEQ0</accession>
    <name>A0AAD8UEQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_638668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000149">
        <property type="protein sequence ID" value="KAK1712257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359375.1">
        <property type="nucleotide sequence ID" value="XM_060509377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEQ0"/>
    <dbReference type="GeneID" id="85393276"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="120" mass="13211" checksum="1101B991047CE085" modified="2024-05-29" version="1">MSESPTTASRNQRDPGSPTITGIPSILTVLREPESFSTIDDRRGQQYRQQSPETASKLARETLISMCKTIGLVGAQLNNGTNDSDFQLRQLIHLARNITKRLDSPEPNGQNGYAGPPRMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFF4</accession>
    <name>A0AAD8UFF4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_79441</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="5 11"/>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359750.1">
        <property type="nucleotide sequence ID" value="XM_060515814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFF4"/>
    <dbReference type="GeneID" id="85399712"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000042">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000056">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="14">
        <location>
            <begin position="177"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="15">
        <location>
            <begin position="345"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1713424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="562" mass="62882" checksum="19301FC6ABD03068" modified="2024-05-29" version="1">MPAEESKPLDPAVKDANDTLAEASDKGKGKEVEVESEDEEEEDAPETAPGATADAPKKKKKKSKRKKVKDALTGKPSDPEAAIKEAIGGLTPQQLTELLALNPALANELGVGSSSNKSAEETAAAMKNLNLQDIMTGLASAGKNAKDMASYKFWATQPVPKFGEAEAKIEDGPIRIQKVEEVPTEASPMVAGFEWVTMNLEDEGEMKEVYELLNGHYVEDDEAMFRFNYSPAMLKWALMAPGWRKEWHVGVRATQSRKLVAFISAIPVNLRVRKNVVTCSEVNFMVVHKKLRGKRLAPVLIKEITRRSNLREIWQGLYTGGVVLPKPVSTCRYFHRALNWQKLYEVGFSPLPPNSKPQYQIRKYQLPDNTSTKGLRELQEKDLDAANELLAKYLKRFDMAPEFSKDEFRHWFLHDKNAPGEQVIWTYVVETNGKITDFFSFYCLESTVINSSKHQVVRAAYLWYYASEVGLATPLDKASLKTRLNSLIGDALILGKKNKFDVFNGLSLLDNGLFLEQQKFGPGDGQLHYYLFNYRAAPIAGGVDRRNKLDEENLSGIGLVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFG4</accession>
    <name>A0AAD8UFG4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_587865</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360364.1">
        <property type="nucleotide sequence ID" value="XM_060506079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFG4"/>
    <dbReference type="GeneID" id="85389978"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053976">
        <property type="entry name" value="PFF1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22251">
        <property type="entry name" value="PFF1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 21" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="699"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="736"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="763"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="190"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease transmembrane" evidence="20">
        <location>
            <begin position="469"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="19">
        <location>
            <begin position="792"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="596"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="664"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1715565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114125" checksum="FB8D02C1B08F0500" modified="2024-05-29" version="1">MAAKNPFGFTTGPVTFWLIVVYAAFLVPLVWIHESVPSVSSHNPYTGVNVTEAWQDLTHITKNYHPYNSRANDEVGAYLLTRIEEILKRNGVDYSMEKDAGGVVWPQDAHGTPALPRQDAVERASTGPLVTVFDDIISNVTYAGTSGPLGQPGSAAHATYFEGTNKLVYIRGTEDEDGEWWKGKRGNIGQGGVLVNAHYDSVSTGYGATDDGMGCVSVLQMLNYFTSPGQQPKRGIVLLLNNGEEDGLYGAKAYHYSPLYYFTTSFVNLEGAGAGGRAILFRTTDLEVSKPYANAPHPFGSVVAADGFKLRAIKSETDYKVWVENFGQRGLDIAFYRPRARYHTNQDDTRHASQESLWHMLSNGLAAVDSLQKTSGSFTGKRNDGDKKKVSSGSGTEGVWFDMFGKGFATLELRGLFAWALTLLIVSPLILVLVTYILSRQDKYYFFSRKVKVDIDDESVPLGGWKGFFRFPLALTFSGAITVLSALLVRRLNPEVVSSSPYAVWAMTLSAFFLVFWTISRGANAVRPSALQRGYAHIWLFILSWAILVAVTTAADRFQIASGYLFAFFHSAVFVATLITLCDLFALPSKRAYAETAHDDQQSRDNISEVPNSDALISPSPHEEGTTEEPTETTPLRSGENGSGNNGTIRTTFATTYRRSLSAIMSNPDDEEEETKETREKQPYEKEQPWSAKLPSWTWFFQLLLLAPITIIVFLQVALFITSAMQSIGADGVDPLLLYTAIAVFSIMISLPLTPFIHRTSSYVPLALLFIFIISLIHNLAAFPFSANNRYKVKFIQRLDLDNGNSTVSILGLQKYARKMINELPSAAGREVICTPSAGLLSDCRFDGSAVLPRLPELKSTSSSGLVSSKDPYAHLVTVNITYSNSTNEYELCIDAPESKQCVLDFDDAVTFDVRESAGIDSLFSTPTEGGINGITLWRRDSSIPWTIDVKPAAKSSVAKPAESVHEETPKEHEELRIRRVRKPAGFSGIISCSWSDANVRGTIPALDEALQYAPDWIAVTKQDVGLVKAYKRFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFH0</accession>
    <name>A0AAD8UFH0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phthalate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_410095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363016.1">
        <property type="nucleotide sequence ID" value="XM_060502906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFH0"/>
    <dbReference type="GeneID" id="85386805"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF65">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="64640" checksum="15953F6B497D61E5" modified="2024-05-29" version="1">MATVLAKNTFQKGEADQSAVSLESIPALGAPIEEKRFWFQRNKDFDPFAVATQPSVFDDPDSAEKYHPREDWENHHRFDPLARWTWAEEYALVRKIDIRIMIWACIMFMALELDRANISQANTDNMLGDLKMSTNDFNLGNTVFKLAFLCAELPSQLVSKWVGPDRWIPAQMILWSIVASCQFWLNGRDSFLACRALLGLLQGGFIPDIILYLSYFYKHHELSLRLGFFWTAMSIADILSAIFAYGLLHMRGVQGHSGWRWLFLIEGLLTLVIGIFGFLLMPAGPCQTASWFRGKNGWFSEREEVILVNRVLREDPSKSSMHNREPITPRLLWDSLKDYDLWPLYILGLTFQIPMTPPSQYLTLTLKNLGFDTFQANLLAIPWTVGHMVTMLAITYLGEVIGELTFVSMSGQVWALPFLIYLNVVDTSGVNRWVLYSVITLLLMYPNPHPIQVGWNSRNSNTVRSRTVSAACYNMFVQTDGIISSNIYRSDDAPLYKRGNRSLLGIVCMNLVLYPLVKAYYVYRNKRRDRIWEGMSEEQRLAYLETTKDEGNKRWDFRFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFI1</accession>
    <name>A0AAD8UFI1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tyrosinase</fullName>
            <ecNumber evidence="3">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_704785</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362128.1">
        <property type="nucleotide sequence ID" value="XM_060511496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFI1"/>
    <dbReference type="GeneID" id="85395394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041640">
        <property type="entry name" value="Tyrosinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18132">
        <property type="entry name" value="Tyrosinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="12">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="13">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1721332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="647" mass="73582" checksum="8C6BD7446FBB2A3D" modified="2024-05-29" version="1">MSSDGTKGPVIIKGIQDGFEGKEPPVRLELRDMIEHQPDQWTLFLLGLERFKDVEEDQPLSYFQISGIHGRPAQKWPNAEWNHVGKNFDPKRGYGGYCTHSSILFLTWHRVYLALFETELYKHVEYIAKEFEKDGVTKYTKAAKTFRLPYWDWARPELPLFPKEALSRKEHTVERPNSQKDDQEKFPSSINPLGSYKFGKYSQAQYANKVPDYVKIVQDNEKTARTFGNINDEKARQKAIESFTRQDFGVKGMNVSERILFLLQSYTDFGAVSNNRAFGSKSNPFDNWGSIEDVHNAVHIYIGGYMGDAQFAAFDPIFWLHHSNIDRLFAIWQACNPSKYVTPQKSNFATIVRDARMDEDANTSLPPFAHTIDGDGNQIFWTSVEVKDTKSFGYIYPETRSVFATREAVINEVDRIYYKRASFANILRSQPPDIETLKALRDRAKAHLTTPGIVAPELPTGRDLPKLAVGDKYLEWLVNIRADKSELDGNYIVNVFIGDPSDSTPPLLYMKDRAHVGSFATFGQAEESPCENCKKGRAENHRITGQIPLTIALVERYLAGLVDSLTPEHVIAFLKDKIRWRITLPSGEEKSPQEFENLLICVVSNEVTFDGKDSKAVPVYADEVTAYPEITGHIPDTYNTGYDGSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH20</accession>
    <name>A0AAD8UH20_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Nuclear thiol peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_549372</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361401.1">
        <property type="nucleotide sequence ID" value="XM_060503476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH20"/>
    <dbReference type="GeneID" id="85387375"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000157">
        <property type="entry name" value="DOT5p Nuclear thiol peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1719317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="145" mass="15368" checksum="F2EFC4E3B8FAA663" modified="2024-05-29" version="1" fragment="single">GETIDLDGFGGDIETNDGEKTTLKELVDKSKAGVVLFTYPKASTPGCTKQACLFRDSYEPLTKTGFAIYGLSMDSPKANTTFKEKQKLPYPLLCDPKATLIAAIGLKKPPKSTQRGVFVVDKAGEVLIAEPGSPAGTVDVVTALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHB6</accession>
    <name>A0AAD8UHB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_720078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364347.1">
        <property type="nucleotide sequence ID" value="XM_060512244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHB6"/>
    <dbReference type="GeneID" id="85396142"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="40820" checksum="26553C7AEE7EAAE9" modified="2024-05-29" version="1">MGEDVDAVGDPGTGDGNGRRGDSAGATRNRTDHKERRRPSRTDNTQDADDGDEDDSDAGSDFSSVSVDELPPIRAYGHTYHGSGVLLMPNDESERARLEIQHQLFKLCLEGGLTAAKLPKDQPLNILDIGSGTGNWAVEMGEQYPLAKIMGIDISAALLPTTVPANVAFEVEDANHDWARDKDSLDFVHMRNLVGGGVSDWKALFRQAYGHLKPGGQIEFAEVRTRYFDLIDSSGDEPVAPTAEEEDHGGMTACREFEVRFSEMAKIAGVDFDPTPKIPAMFSDVGFEKVARWSDLVPIQAVGHDEKMVRKGAQFAQMLEYGLENYSLAVFGRGGWDENDTRSLLKRVHKESRDTANEAYGKVSFVTARKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHT1</accession>
    <name>A0AAD8UHT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_722050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361579.1">
        <property type="nucleotide sequence ID" value="XM_060512429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHT1"/>
    <dbReference type="GeneID" id="85396327"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1719495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="337" mass="37320" checksum="EA918234D5507A3D" modified="2024-05-29" version="1">MTRREDRLDEPIYAQYRFSHTVPSGQGIAPHIRLLSISEDILATVHGERDVLIWNVKLNLPPQRIEIDIVLDHITGIAISPASSNVIALSFQLGSKCEVWTFNWADKTPEAMFTTGLDFHSPQFSPDGRLLAWISAGCVDVWETIIDTHVQTISESKKVTSGRPVSRFAFSTDSSRLVTVDRSGRLVSWDIATWSYIGESKAQPAMDNSGWEPVQLVTDARRVMMVSRGVDGEVPQRWRLTTWWPSSGNRAELEMDGCVYGCVPGNCAFVATVQSDGGKLRIRDANNGMCFDQSTQGIAKRGKTPSVVMGDMVMSGKIMVTQIANGRTTIWQLVATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIB1</accession>
    <name>A0AAD8UIB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_752673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364486.1">
        <property type="nucleotide sequence ID" value="XM_060514234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIB1"/>
    <dbReference type="GeneID" id="85398132"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF69">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="58982" checksum="18C4C5A7097E92BC" modified="2024-05-29" version="1">MPSLRPLLDPILGPEPRQPDRIPTDTVVQLSAMDSSWMMRMMIMSWSMCFHDVLDPVMLHDSLSELLTIGNWKKLGGRPRLTKDGKLELHIPQSFTPSRPAVHLTTEPNPSSVSTHPLSSTIPSFFFPPKTTTSSPNHPIILDTPSTLTPLLAGPEAPRTFVDYTTIDRPLLTLHIITFTDATFVTITYPHSITDGMGRRELVENWCRVLSGRHDLVTPLADLSSDPMAKVAYAEKQRYDEPFLWEHKRLNGWGKVRFTLGLLWYLLTNRIRQRNIFIPATALLRLRERAEADVATPADEEPTTTGRLSDGDILTAYLVRLACSHIPSTSPTKPISISTALDLRGRLHPDDLPAGEAHVSNLVAYNWTNTTALGLLHAPFGKAVALIRNSVRSQLTDAQVYASTRLTYTAVAESGSTNQFTEANGFVVSVSNVGKARFHEVIDFSPAVVKSEEEPRDEGEEGEGEEEKEERKTPRGKIVWQCNTPRMSLLPPCLIYIQGKDHKGNYWAQMVVSERAWRVIEDEVKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIC0</accession>
    <name>A0AAD8UIC0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362264.1">
        <property type="nucleotide sequence ID" value="XM_060510697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIC0"/>
    <dbReference type="GeneID" id="85394596"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF11">
        <property type="entry name" value="ZINC-CONTAINING ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="32902" checksum="23B5C647C1EE5A7A" modified="2024-05-29" version="1">MHAALVNTWGSPPTYTTVPDLPEPSPTQIRLRVLATGVHRLVLSRASGKHYTASTLPHLPGADGVGEDPTTGQRYFFAALAAGTFAEFVNVERAAASPLPEGADAAVVAAYMNPVMSSWMALSARATPQQKGFSVAILGVTSASGRVAVDVARAKGAGRIVGIARNAAALEEIPIDERIVLNGEETDWSKLGEVDVILDYVYGNPVVEMLKALPKSEREVQYVHIGSVSGDGDISLPGAILRGKRVALRGAGPGSWLMREYANELGGMVGVASGLKGKEVKVIAMKDVEKGWSEAGLGKTRVVFVSDDLVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIN0</accession>
    <name>A0AAD8UIN0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_753069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364003.1">
        <property type="nucleotide sequence ID" value="XM_060514295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIN0"/>
    <dbReference type="GeneID" id="85398193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016864">
        <property type="entry name" value="UCP028035"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028035">
        <property type="entry name" value="UCP028035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="10"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="957" mass="108249" checksum="A0BD518C7ECC829F" modified="2024-05-29" version="1">MAIPNHFVVYKRDARQLAYWMVHASNFIFKTRKRDDGAWESPIEFNTTGQIHVDDFQSVAKFVSKHMQAIPPATFRLFRSVINARTEHLVFLRRIVSEEDPQYGKDIKIHDTFVRLVTEAFVALGGDAWIETEQPRGVQGRSDSSNLTPEKLADFINFSASDLKSLSLDSSGENSSDAVPAPLHGSQRRAQAKSGRGGKGKKKAKKAPAALLNQVPIEQYSIVEADGIGKAESFMAACAIAKECVILRNYLQNIWREAAYVFGECPELQSYETFIAAIIRGNLETAQGSFIKALAKLSPASQHEGTKTTSINLKEYIQLGAYRDFVDFLEDYQQSEDGKPTTKMLVKIKDWDPTLDLQHTTKRERLKWRRSYTINWLYDLVNSYTAPKRRDGEWVRLENLPNCPLTGSEPLLGLQDFACFVTSLLMKKPGTDVLQDIMPHRVFQLQCIVDAFTVSCGWINTTRRGHVLGPRSPDTLGPMKDIDGFLGRRPIGNSTQEIGSNDKGRGKGGTKLYIGDIELSIGDNEKDDGRIQNDDKKLGVSNGLLRSANLMADFYGAEFRNAHRQPMMGFLSVFCREFDFLGQSVPMNGDILPISRFDRTGLNGMWRYSPYLCGVGVMEGLERVYRTSMLIWDSLEEPTAMIHLHNMLVQNGHIKKPLAHYQVLQEMFRESFFLDGQVPQSNFAEAFLGIGELLWGAGRAKQEPALPASAGYHRSVDVSRNVAFKTKSHMLLYREANWHVEWIPDKALNPRTRLALLRASKLIANTPLNSMTKDQKSLIDRVKKALGVDDQELLSRGNALLKKLGETRPHQSSTGRNGRPIEVVFRDHVRPSRVQILDLIKADLYDDICGNRSYSTFNYILLYVNMIETFEKIEYELARAQDSDCQGVLELGTRLRMVDGLLRKERERESVKVVAKVFESQRELPCRYPRNETSVRPSLLGEDTLNYDEEDMLCSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJP7</accession>
    <name>A0AAD8UJP7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_577068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365206.1">
        <property type="nucleotide sequence ID" value="XM_060504981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJP7"/>
    <dbReference type="GeneID" id="85388880"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042256438" description="Ankyrin repeat-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="19633" checksum="30E3E68C42AC11E3" modified="2024-05-29" version="1">MLCAHLISMLLSPFRPCEGIPTFQEEYRGTYAPNFIEAWHGPQIVAPDTPYVAAAGKNSLYFIDSRFDSDVAEHIKTQIERATVVVGPEEVIAIDEIEATAEVRNSVTGETVFVFDSAYARVLFARGINRRNPKIQLPELELAGDWLVTYESGLAAKREDRQTGGERNSDSWSHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJW6</accession>
    <name>A0AAD8UJW6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_578435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364663.1">
        <property type="nucleotide sequence ID" value="XM_060505121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJW6"/>
    <dbReference type="GeneID" id="85389020"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="704" mass="79416" checksum="3C67CA95F8ED4934" modified="2024-05-29" version="1">MSSQYAGGSLPEDYEEKAPHIGQHGLVNVELDRSSGFPGPVVNGLTQGMQTLALAFCQNCWSTCAVTNDGYQPLPGSEVATYDYGTNSNRPYEVEKPPSAQVSQPDAYVPAPVVSNTQNPFPAGDNSLLGSYVSSYQPVQEDPNQTLVSQHSGPDTGVYVTEVSAPSFYSTTPSGHVGGEPSYSNANSLDRHLTPRETMPPTYGGSMMDMVISPALHTPTSVPVSTARFAMDSTYPMSCVKTEDMDGSIANTHVNASLDVVFPNQRPPAAKRGPFKDQKAREETAATRKNGSCIRCKMQRVRCKTDPDDPKGPCLGCKPRPNNNHHKQLIRQPCVRHKITECHFFKKGQAPGFEWTQRFNNGIVDNINNWASNEVRIVRLWEGYTPSSMWVQLSVREFVPQPGDKLERTWVTEEGEKKSVAIPTYAITNLDDAQTAYEDYIKRGVVECFNSVVESVMGVRDRLLFETYLKAWKLSQDPSTAQDEKDLLLQTLELWMAVRLTTKSIEIVGDDTLGMTRDILDSSSPQHGRIPLPPVMGAQLDLVLIQHIQTRLRREMLEKLQKMTLQNKQKTWLTTYLVTFMLLHNIALVTDHDASYARKHGMKTKFARQTDVQEYHMGGTILLAYFHYCNKGIYPFSEDCRDQDLRTLAQLDDDAVQFIHYTRAMAMQNKREWEEVQRANQYEQPYFFVSQLFQRDWQPQTWAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK25</accession>
    <name>A0AAD8UK25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362886.1">
        <property type="nucleotide sequence ID" value="XM_060514421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK25"/>
    <dbReference type="GeneID" id="85398319"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF4">
        <property type="entry name" value="HYPOTHETICAL AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="207" mass="22369" checksum="AA55924D120A93CA" modified="2024-05-29" version="1">MSLAQHVTQAEGFDYERPTEHIESTGNGESIFGTLNPFNTDSSNDDPQWRRLSFAPVETLHAEKPIAAYKVSNTKRWVQVATSIVACWLAAGIVFGFAALKPILIAEGVYSNLCDANDPGVVGDGDYIPCTEQDLRLNLFFIAASVTANVSSLLAGSVLDRYASRNIASFDGYSLGNIMLALGGTFVFVSSFQLANYRPNLYNGGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKB8</accession>
    <name>A0AAD8UKB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_582326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362854.1">
        <property type="nucleotide sequence ID" value="XM_060505541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKB8"/>
    <dbReference type="GeneID" id="85389440"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021514">
        <property type="entry name" value="DUF3176"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11374">
        <property type="entry name" value="DUF3176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="639" mass="71318" checksum="23B0AA9D4B08C0A4" modified="2024-05-29" version="1">MDSRGQDDETRQVRRKPVPSYVPPLGYDEALLLSSAHTHVYDWDQEPESTARTSDEPRSTEIGRDLPSKSTFASGETEYELVKTSSAEKTRNHTRRPSRRRWQILKGWWPEIIWCLISVVCIIVLVSVLRSYDNQPLPNWPLGLTLNTVVAFISTFCRTSFVLPVVESLSQYKWNWYKSPRPLGDFAVFDEASRGPWGSLKLLLRTKGRLVGILSAVILVSGIATSTLTQSVVTYPTRHVAIPGNETALTRRNNEYFWATANGPSRRDIMFPINQIIPRSLYTPPNEVMPYYQASCRSNNCTWDDFTSLAVCVDMKNVTDLLETDGDPIEMGTNSTLPNGLRLQRSYGYGNLNISSGPSLAFNGTDAMEAKIWNFFVISGPRLRATEIMLHWCVNTYRVTVQDNLPVTQKVASYTNPQTGEVLVETYNMTSNVTYLTSPHNPGKKYVADGMGPAEIADILDSTLSGTYIDGGTYMFQNGTQIYGTALSRAAIGINETTESQRLDDALFTTLRNLTENIASGLTNALLVSNVSGTAWQEERFVSIRWPWLTLLAAQVGLSILTLAIIMVETASLDIEIVKDSPLPALLAVHPDEKSVLLRDHVEETPNKDSRLPHLRASGITGGLRRDGEDWVLQGIKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKH3</accession>
    <name>A0AAD8UKH3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Alpha/beta knot methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_751657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365671.1">
        <property type="nucleotide sequence ID" value="XM_060514084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKH3"/>
    <dbReference type="GeneID" id="85397982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000003">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="340" mass="37220" checksum="8797375A05704D3B" modified="2024-05-29" version="1">MSSPEARAGVKRPRSSLLQLSAAVIAVISGTSFFAVSLCASPTLSIARTISWLKAVATPPPCTLRLVPYPKHYISSIKYYTGSRDTMEDMADSTQSLPPPALPQLVAEQHTAIPPTDKDSQRLIVVLSNASLETYKASHGGTGRNGVQREEKYSLLNSDEHIGVMRKMNRDISDARPDITHQCLLTLLDSPINKAGKLQIYIHTAKGVLIEVSPSVRIPRTFKRFAGLMVQLLHRLSIRSTNSQEKLLRVIQNPITDHLPPNCRKVTLSFEAPLVHVRDYIDTLAPKESVCVFVGAMAKGADTFADGLVDEKISISNYSLSASVACSKFCHAAEDSWDIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKJ1</accession>
    <name>A0AAD8UKJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GA4 desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_720658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363449.1">
        <property type="nucleotide sequence ID" value="XM_060512292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKJ1"/>
    <dbReference type="GeneID" id="85396190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="34484" checksum="A78D26933C5EA853" modified="2024-05-29" version="1">MPHSTQKPESVEAYVNYHQPPPKGEAFPVQMIATVGFQRTKYNRQLVPVTDMRTCDEEFSLDTQGFKVVESTVQERGWEGDYRFGLPDQLRKDVQELLMRHSGATYVHPFAPHVIRRDPHEKILNIPEDLPDSQVLNMQPPAMFIHVDQSYKGAEVVLDRLPEAEMLRTKTKTRWGIINVWHPLKLVQREPLAVCDARSVEEPDLRPVTTRIVLGKPPNTINKDNEQWHMVASPQHKWYYASNMTPDEALLIKIFDTKLDGRARRVPHTAIQTPKDVGPPRESIEIRCLVFWEDQELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL76</accession>
    <name>A0AAD8UL76_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">CAP-Gly domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_673345</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363839.1">
        <property type="nucleotide sequence ID" value="XM_060511136.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85395035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000743">
        <property type="term" value="P:nuclear migration involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="79"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1019"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1723784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1315" mass="146065" checksum="FA7C128494848DA7" modified="2024-05-29" version="1">MSELAVGQTVRLSDGRTGIVRFAGGTHFASGDWVGIELEDDSGKNDGSVQGERYFDCALGHGMFVRPTTLAIIAQAPAPAAKPAARRPSRPSSFNPGAGRTTSDTGLTKRMSLNAPSPSPGPKVSRPASTLRSPTKSPTKQLGSATSSTAPSRTTTPSNTRTPATAAKTRPSVGTSRSSMGPPPIPANRTTRQPSTSSAATRPTPGRPNSGRLSISGRTASSARRPSADMGAGKNVDSGEDAGATSPNKDGETSPVRARTKALEKLTSGSASTTPTSSTKPATTARSTPNAAAANREIEDLKAKLKVLERKRLEDREKLKQLDQVQGERDRFQSIIEKLQAKYQPQQSENNELRKQLKEAEERFESIESMQMEHETALELATLDREMAEETAEVLKVELEALKQKSEELELEVEILREENAEFGQGMSAEDRASTGWLQMERTNERLREALLRLRDLTQQQEEELKDQIKTLEDDLQEFGTVKEQFDAAKEKLAQSEAAVEDLRQQLDNALGAEDMIEDLTERNMSMSEQIEELKAVIEDLENLKEINDELEINHVQNEKEMQEDLDFKDSVITEQARRAGEQEEALEDMEYTLSRFRGLVTSLQSDLEDMRASHAVTETESEQLNSKSRAMMDLNMKLQISASKAQVKTIDLELRRLEAQEAEQHLEIVKMFLPDTYKEDQDSVLALLRFRRLAFKAELLQSFIKERVNGQPHSGHEDDVFAGCDAIDKLTWVASMCERFTNAISHCSIEQFQRFQNALFELEPVERALNGWIDGLRRDDLKEQKCADELQRTIALMSHLAEVHLTNELPDFAEDTYMQTVVMQSHLESAGATFAALRGMVQRVVPSESEDDEMAQHFSKKSEFVVAQTRSAKVIAGKAVRALQDLKSRSLALPQETKESFEQCQDATQQLAALAREIGSDLHTLLHEEGRNEPFTYREVQDSISKATTKVTMSSESDLFSTYLSRLRTLTSQISDLAALSADLSQTQEFEVSPAPWKLRAQELKAIKTIPVDAEEEMRRLKEEHNEARVAIAQRDENLSTANLKIETLESRMKDANAKASRIEDLEAQIEAAKQKAGSLKEDIDKQDRELKMLETDRDKWKKIAGDSKAFADGAGAAGAKAGQERAVATAREMDALKSEIASLQAAVRYLREDNRRARMTEQHNYDWLAEPLTKSPSIVEQRRALVVAEGKDVLSELVKFTTSARVYDLASLPEDKLAWKPARSTPQYQAAKQREDLAAWNSWRNSVLKKSEVVLGRKDGAAAEKKQMMKSVAARLQIRLPDADGKMVPGGGRNVQIVGSREWEGIQGRLAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULF0</accession>
    <name>A0AAD8ULF0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nitrate reductase [NADPH]</fullName>
            <ecNumber evidence="6">1.7.1.3</ecNumber>
            <ecNumber evidence="5">1.8.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_304128</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>nitrite + NADP(+) + H2O = nitrate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19061"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; sulfur metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.3" evidence="6"/>
    <dbReference type="EC" id="1.8.3.1" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365548.1">
        <property type="nucleotide sequence ID" value="XM_060502267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULF0"/>
    <dbReference type="GeneID" id="85386166"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050464">
        <property type="term" value="F:nitrate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="16">
        <location>
            <begin position="150"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1725493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="647" mass="71350" checksum="B783C81A7C0988E7" modified="2024-05-29" version="1">MQAPRRLFSELLQLSTRRPVPPRSTLGAWRPSYIPDAPPPPPGCRPLHASACSRHPRPISASSSSTPLVGGQEHTQKHHTTGTWSGERGDEREPQHPRRRKGPATVSTLLASGGLLSLFVGLSEPFHVPTQDEVDASDPAPSTDDRDPSIPRFRLSEIRKHDAKSSSPWVTQGDKVYDITDWVAAHPGGDVILRAAGGSIDPYWNIFTIHKSPHVYEILQQYLIGFIDSDDLVDGKPAAQEIEDPFKHDPTRDERLITLTPKPRNAETPVEGLADSYLTPNELFYVRNHMWVPQVDDTSDYTLKIELLDGTIKEYTLDDLKTKFKPTTVVAVLQCSGNRRSDMTRNAKKTNGLQWNVGAISCAEWQGVKLTDVLADAGIPILEAMTGDTEAKHVQFMALEAYGASIPIQSALDPRGDVLLAYSMNGKPLPRDHGYPLRALVPGHVAARSVKWLSQITISDEESHSQWQRKDYKCFGPNETSPDWDRAAPIQEMPITSAITTVRLGDWKAAASESAANEDTGSVREASLMGYAYSGGGRRIVRVDVSVDNGKTWDQAELLDEPGAPPKTGHKSWAWKRWRYDGAIPLGEPGEGTKKCTTLLVKATDEAYNSQPESYAAIYNQRGNLANAWHRLKICSDCANKAMVVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULW9</accession>
    <name>A0AAD8ULW9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GAR transformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_751407</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365818.1">
        <property type="nucleotide sequence ID" value="XM_060514046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULW9"/>
    <dbReference type="GeneID" id="85397944"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.170:FF:000009">
        <property type="entry name" value="Phosphoribosylglycinamide formyltransferase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="10">
        <location>
            <begin position="9"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="24754" checksum="A94D5B752277A0A9" modified="2024-05-29" version="1">MSSSTEHCRLVVLCSGSGTNLQAIINAVADGTVPQSKIEKVIVNRKTAYAVQRAEKAGIPTRYFNLVSGGFTAKGEKDEAKLKEGRGRYDAALAEVVLQDKPDLIVLAGWMHVFSAPFLRPLEAAGVPVINLHPALPGRYDGANAIGRAYEDFQAGKLENNRTGAMIHYVIETVDRGEPILIEEVEIRSGDSLADVEERMHNVEHGLIVKATAKVVQKILEKKKKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM77</accession>
    <name>A0AAD8UM77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_618151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365998.1">
        <property type="nucleotide sequence ID" value="XM_060508063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM77"/>
    <dbReference type="GeneID" id="85391962"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="253" mass="27825" checksum="C3C084A21FACEB82" modified="2024-05-29" version="1">MGSQPPRIRLAILEADTPQPQTNAEYGGYGGVFTALLRTAALASDPPAPLDSIVDLSVYHAVGDDAVYPDLDSIDAILISGSKHNSFDNDPWILKLVEFTKKCIDSGRVRVIGVCFGHQIVGRSLGVEVKRSDLGWEVAVVDVNLTPKGKEIFQLEKMRIHQMHRDVVTENPAGAESLAYTELCPVQGFYSPKKFITVQGHPEFTGPIVSEILNVRHKAGIFDEAMFTDAINRANIEHDGVNIARGFLRFLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNI4</accession>
    <name>A0AAD8UNI4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_312620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365370.1">
        <property type="nucleotide sequence ID" value="XM_060502311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNI4"/>
    <dbReference type="GeneID" id="85386210"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="93"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="20144" checksum="90B5DF6BFCD371D2" modified="2024-05-29" version="1">MSSQTPLYKPLPAPRRIVTTHNAAGQAILITDLASELPKGSVPGTDLYLAYSSPSLPAPLPKDADLNAYKTHLTLKPPLEIGIDIPGGLAARVVDFLPGGPGAPMHRTETLDTGVLVEGELELVLDSGETAVLKRGDVYVQRGTMHGWRNVSETETARLFVVLTAAEMPVFGGEKLKEVMPVPPTDSGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNM6</accession>
    <name>A0AAD8UNM6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UBA domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_751832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365460.1">
        <property type="nucleotide sequence ID" value="XM_060514105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNM6"/>
    <dbReference type="GeneID" id="85398003"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000026">
        <property type="entry name" value="GTPase activating protein for Arf, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF7">
        <property type="entry name" value="ACTIVATING PROTEIN FOR ARF, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="4">
        <location>
            <begin position="14"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="210"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="610"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
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        <location>
            <begin position="391"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="498"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="610"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="714" mass="78368" checksum="09F52AF3943DC459" modified="2024-05-29" version="1">MAGVLSKRQQARNEKVLHDLVQSVPGNNLCADCQARNPAWASWSLGVFLCMRCAAIHRKLGTHISKVKSLSMDSWSNEQVENMKKVGNVRSNQIYNPDNKRPPVPVDADEADSAMERFIRTKYMNNIPIPTRKQHSGLSDEGVPPPLPPKSGGKFGFRSASSIFPLSSRLRKDSSLRNTVSSPREPRSPSPSDLPNKPSKVFGASVSYEQEDTERKLTSLRDMGFSDGQRNAMVLKGVNGNLERAIETLVRLGESDRRSPSLTGPRESSLRATRSHANLSTSSGLSAPHQTFSDHPQSPSTASSNNPFDMLPPQPQSSQSTGTLQNKNPYANNPFGAPTQQQQDIAQAFGSMSLAPAQPLFPHHTGGLPASQPFAQPQQIYQQSMTPPIPQQHQQQNYNPMSFNSNMTYPQPIQPQATGYNPFLTNQAQPQQQQNLAVNTGPSSSPYANNPFTRSPTRIQSPSLGQIPEQSQSNFYMDSPQTMTPQSSNPFFAQLGSQPTGQQQVPQQQQQMYQQPFQQEQQAFGQQQQNPYQQQHQNAFQQPVQQPFQQQQQQPHHPFQQQDIPQQQYQVPAPQAPYQQQPQYPQQPQRPDKASILALYSQPQLAPQAFAPQTQAQTPEVHPEVAAPQQQSQDAAGGSMGAGSKNPFLMNGGGGGGGMSSPPPPQQAMAAPSANAVGPRKAGVSRESMAFTDMQWTNGRHSPDAFASLSARHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP19</accession>
    <name>A0AAD8UP19_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_718094</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060512027.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="85395925"/>
    <dbReference type="Proteomes" id="UP001244207">
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    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
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            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
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            <begin position="17"/>
            <end position="28"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAK1726888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="457" mass="48983" checksum="B6F98CEAA12632E7" modified="2024-05-29" version="1">MASSKQTTRPLNQHRPSLSTASSSALTTRQSHSRTNSHSILSGALNANHRVTRRKSMTNTAANAAAMAAAIKEVGGDKVTPIAVSSRRNTASKSAAARAAIIGSLPSPPASLPTHKFHLDGKTEIHESAIEDDPINGSADEGDDNAEKARIRRASDGQPLVKEGRKFNRIELKCETCGKGYKHSSCLTKHLWEHTPEWSLTSKLLISKHQQVQLLEAASVLLTMNHKEEGDAATPPDSAKDFPSDQEESTSPAASGYSDERHSSADTTPPPQLEGFSSSDRSFAKRYGSGSGFGRSYQSAPSINPLVTGSMPRGSGFSSHFRQTSQDQRPPSSGRNATGQEDQDLAAAVELLSCSFNSNNGRTVQLPADAPPVPPLPAQYLDQAASFSSAGFSAGFSAGFLNSFPSRQPESFTRGEVRGSVVKMEDSDSVMDDDDFDRRSRSRSDEDDDGVFGRMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPM0</accession>
    <name>A0AAD8UPM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">KH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_274741</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366030.1">
        <property type="nucleotide sequence ID" value="XM_060502085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPM0"/>
    <dbReference type="GeneID" id="85385984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22448">
        <property type="entry name" value="KH-I_ScSCP160_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22450">
        <property type="entry name" value="KH-I_ScSCP160_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22408">
        <property type="entry name" value="KH-I_Vigilin_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054548">
        <property type="entry name" value="SCP160-like_KH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF31">
        <property type="entry name" value="DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22952">
        <property type="entry name" value="KH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="202"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="284"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="378"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="697"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="764"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="858"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="931"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="1012"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="1081"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="1195"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="807"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1274" mass="138130" checksum="80A7AD182BF14400" modified="2024-05-29" version="1">MASTDSTVANGAETSAAQRLLQTHADLHPTVEDVPDEDLPVKSGDAPSWAEPSSSRAASKQKEASASGKKIDTHSHELFPELGTSKGKSAGPNVTPIWGAKSNASTPANGVSRSSTPASGAATPKMSIPGRNVETVVLDPQFILPRNQLKRPIPDIMKDINRKSRANITLSNGPNGKLKFEATGPQDVAQQALKDLVQQIGTKTTIKVPIPQSARAHIIGKGGSVIKSIQEKSGARVQLPKAEEGSGPIDEDDDSTIDVLVEGNALSAASARNEILKIAGDRTANLNSKLRGIPAEFYPFIAGPGNSHIGRYENNGVTVRVPAHQIWAPRGRSLVANEGERPVFVPAADNHIQLQGDRAAVQAARAEIERRVQELQNQLAIDQFSLQKGRHQFIAGRRGETLDDFFNQTGCTILLPTDEDDDSVTVIGPAAQLTKGVETAMDRAMNMQFSTFDIGRFHKNAPGGVNTHARNVTRYLRHRDLFDDIESAHNTHINTPFTSAGASPYELYARDGKSVLQAQSAIEKLVHAIPPARIAPIPVDPFYHNYLVKDVSPRMKNSHGVHVILPESGEPEAPVLLVFEGPSASEPKPEIKTGRPSQDEIQAFQKGLEEARKQILDIINKQEQIASASVDVPQKFHERLRRFIKKEQANRADDQIPIRVSSVGTVVNLRGPASAVKNLEAKVVAFVEQEKEDEKERGFTMSFDFPQKYANHLIGKGGSNIKELRDRFDVEIQVQDGQVELKGPKAKAEAAKAHISSLGRTLADEVTHILKVDPKFHRELIGAGGSVTNRLQSKYKVLIFFPRSGKNAKDEENADASSDAGKPKRQQEPDEVIVRGPKKGADEARDEILSLLQYLKDTSFTATVSVQQKQVPSIIGQGGAALEELRVATGAKIDIPSARDAETVEILIKGTKPQVAAAKKALEEKRDVFNDTVVQTIEVDKKHHKSLIGSGGANLRDLVVKAGGSDDRRELARTIQFPKQEADGNTIKVEGRSDIVNKIVARIQEIVAEKESQVTEILEVPIEKHRTLIGRGGDAKRQLESQFTVSIDIPRQGDGKTGVKITGRPENVEKAKEHIASLVKEQEGETLQVPRSLHHSISNNGQFFRQLRNNHQVSVDHAGQALPPKPSAAASRSNGGALPLITDDEDATADAHSWKVVDSAAGEDGEIAWVLRGSPENLEKAKAAIASAIEQAKKNTHTGYLVLPDPKTYRYVIGQGGSKVNSIRKQSGCKINVPRNDAKEDAIEVIGNADGVEKAKDLILEAVREGLSSRAPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPW7</accession>
    <name>A0AAD8UPW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_359265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364355.1">
        <property type="nucleotide sequence ID" value="XM_060502564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPW7"/>
    <dbReference type="GeneID" id="85386463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070813">
        <property type="term" value="P:hydrogen sulfide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000033">
        <property type="entry name" value="MBL fold metallo-hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051682">
        <property type="entry name" value="Mito_Persulfide_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084:SF1">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="34423" checksum="BB49EEB1EFF11DB5" modified="2024-05-29" version="1">MSSLRVAPVDTTQPVIHDVFESRTGTWQYVVADPATKAAVIIDPVLDYDRTTQIITTSSADELLRLVKEKGYRVLRILETHAHADHLTAASYLQKRIAEEHGNKPQIGIGRRIGQVQDLFGQRYDVPSQERHGVFDKLFEDDETFSIGNLSATAIHLPGHTPDHLGYKIGDNVFCGDSLFHVDIGTARCDFPGGSANNLYHSGRRLLSLPDHVKVWTGHDYPPDDRESPVPWMTVSDHRKLNKHLRDGITEEEFVAQRKERDAKLGEPKLLHQSLQTNIRAGKLPQPTASGHRMLRVPMKLGDLQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ96</accession>
    <name>A0AAD8UQ96_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_614253</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366947.1">
        <property type="nucleotide sequence ID" value="XM_060507818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ96"/>
    <dbReference type="GeneID" id="85391717"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF56">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="235"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="477" mass="53111" checksum="6B4181D67AF61927" modified="2024-05-29" version="1">MTRDSARACDLNVYFAALKLQSQPTSAHVSSVPVEERSSQLSTQTLGTNQETSLTDQQQDPKQIDQSDERDLTARFEGEHSSAEDNHYLQPGHELLAEVSDSSSHNPPTYCRNQSFLSGLGLRSRKLIGSNSDSENDEDVDGNVEQDNVYDSDLDSTLGSTGQQNHARKMRKWKGLAKGRFERMLLDCIVNTDNIAPNYRDIFIDPSIINKLEQVTSLSLLRPKAFSCGVLKGNKVTGSILYGPPGTGKSMLARGMAKQSGFNMLSISTSEVWQKCHGEDEKMIKAIFSLARKLYPCIVFVDEADAMLGARKAGEKRHIRSMLNQFLMEWDGLITDTRAPFVLLATNRPFDLDPAVLRRAPVQIHLNIPTQEERTGILGLLLEGETLQHINTDHIAKLTPNYTGSDLKNLCVMAATNCVNSQLRDTTERILTREHFYTAIQTISATNIGRVSANEFKRFEERLQGNIEGSARDADED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQC0</accession>
    <name>A0AAD8UQC0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_749851</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367588.1">
        <property type="nucleotide sequence ID" value="XM_060513829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQC0"/>
    <dbReference type="GeneID" id="85397727"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF63">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="3">
        <location>
            <begin position="62"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="47927" checksum="BE2EC90E7E69E24D" modified="2024-05-29" version="1">MDHGLSTRGSIAAKPDDGMLLWKIVQDLWDPETNPKGYVSLGIAENTLMHDRLSKHIHENLAVPNHSFTYGDGMTGSKRLKVSLARFLTERLHPVTAIEAQHVSVTNGCSSAIEHLCWALGNPGEGFLLGQPHYGAFLPDVEYRTGCKLVQVPFREVDPFGLDAVRKYEEALLSAREKGIKIAALIICHPHNPLGRCYPRETIVDLMRLCQKYDMHLISDEIYALSVWKNTIDTQPAPVPFESCLSISTTDIMDAHRLHVLWGMSKDFGANGIRLGAIISQHNSSFHSSLTPVGIYSSPSGLTDHATANILDDREWVNGYLDENQRKLQENFELVAHWVTENGITYAPGANAAFFLWVDLGKAYRERRPGVDFEDISTEVMRALLDKKVFLASGKQFGAEQPGWFRIVFSNRKELLLEGLKRVAAALNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQD5</accession>
    <name>A0AAD8UQD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_575738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365883.1">
        <property type="nucleotide sequence ID" value="XM_060504844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQD5"/>
    <dbReference type="GeneID" id="85388743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23164">
        <property type="entry name" value="Prefoldin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="119" mass="13654" checksum="17C5D4F5E4E2DD72" modified="2024-05-29" version="1">MSIPNQALEKLIREIESQAIVAQQQIGQARTQMTAKQREMRMVRLTLDEVSTLPSNLNVYEGVGKMFVALPTPQLTQKLEGQIKDREGEVEKLSQKLHYLETTYKNSRQHIDQMLKAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQR4</accession>
    <name>A0AAD8UQR4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_617611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366063.1">
        <property type="nucleotide sequence ID" value="XM_060508035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQR4"/>
    <dbReference type="GeneID" id="85391934"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007584">
        <property type="term" value="P:response to nutrient"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="80"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="43973" checksum="D85A8A7996FDA873" modified="2024-05-29" version="1">MRSSSISLRPLRRALAPSVSTQLLPPLVTGPRLYSTHPPNAKLNIPVDYATTSLLAHSSQTALGTANLPAEVRDGTTKKMNLFQAINDALSIALAEDDSVMVFGEDVAFGGVFRCTMKLAETYGADRIFNTPLTEQGIMGFAIGAAAEGMRPVAEIQFADYVYPAFDQLVNEAAKYRYRDGACGRSVGGLTVRMPCGGVGHGALYHSQSPESLFTHIPGLRVIMPRSPLQAKGLLLAAIRSNDPCIFMEPKILYRAAVEQVPAGAYTLPLSKAEVLKEGKDVTIISYGQPLYTCMSAIQKAEEELGISVELIDLRTLYPWDKETVFQSVRKTGHCIVVHEAMVNAGIGAEVAATIQEDPDTFLRLEAPVARVAGWSIHTPLLYEKFNIPDVARVYDNIKRVLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQV6</accession>
    <name>A0AAD8UQV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_544553</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368371.1">
        <property type="nucleotide sequence ID" value="XM_060503439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQV6"/>
    <dbReference type="GeneID" id="85387338"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF8">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="20"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="23420" checksum="3C5714969A62794C" modified="2024-05-29" version="1" fragment="single">RGIIGGVDNRVLWTNKDYPYRAMGRIALSNGAICSGALIGSRHVVTARHCIPENGATARFQPAYDNGEALGGYDVIRVFRPDYGQEGWCANAYDWAIFVLGEKAGSTNGWLGLKTVNPDTQLNRAMFFHYGYPGDKGGQQAYRQEAITASSATLCDRGSPVVTDADAQGGQSGGPFWINENGDRYLYGVVVGTNDQITVVAGGPSLLEGYGILLKDYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR74</accession>
    <name>A0AAD8UR74_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polymer-forming cytoskeletal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_573578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366945.1">
        <property type="nucleotide sequence ID" value="XM_060504627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR74"/>
    <dbReference type="GeneID" id="85388526"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="23674" checksum="23A006771F34F48D" modified="2024-05-29" version="1">MAPKSKQSSRKGKEAAAAAAAAAAASAAQYEYYDEVSPAGTTGSYYASSSTTATTGPSPLTEYDETPGAAAVAGTTTAVVQSKSIRSEGEIVLQGPLEVAGSVKAGGNITLNGDFDVRDKVEAYGTVDVNGNLVCDGKMKAYGNISVVGYMSIGDKVKGFGKLRVMGTCEVNDLEIYGNTTIHGFLKCKKLLLYGSLTIVGPNSGYHVEEDEKIWGAIISREEDTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USE9</accession>
    <name>A0AAD8USE9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_610766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368012.1">
        <property type="nucleotide sequence ID" value="XM_060507606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USE9"/>
    <dbReference type="GeneID" id="85391505"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="833"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="865"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="991"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="915"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1089" mass="125664" checksum="D8F1179FA3785685" modified="2024-05-29" version="1">MVDANDGSFMPSDSFTDTPFHLLKISAFMDTHNSNDYRRLARRVIHKVAKAWLHTLDKSDKRASHVWPHARDEGYNKYRLNEHVWIWRALKTIEDDRRRSSETKDHPNDGEIDREEVAEGDTKDRKVLDIGQRDQHVSDDEKIFRKFDSDVIQRDILRRFTVENDVSKKRMLAMTRSPRETRFLLHASDTALFYGIKWNFFLQTLFDEVWDNTIEAQVHHSENSETGWDNSIRYALAIMMGTRNMTLNKRSPNDLVKSAFDVLLRSTNPNGLFYGQLDGTTKEPALFAREEDRDFYFLASFEIPYVLLTHLPKIDSAYKDITGKDPKSPVRLERLQLTPQHPFNEVADMITQQPKRQEHRSPTNQGSAADAGESQNMSAGLYQNVKSKRPKTTAMKKSVPFNSFIDQSSIIDLDDEWLYNYPSFLGSDEKTAESLHEEMRKFLGPTWPNNISTRVNNTNIVITKAAEKYMQRLSEPKKDDALPTSDSTFFTNYNAIEMYSCVVNVRKQKNLSKQERADGDECHYISGSLSLWEYLSRPRVVKEAKKRLIWLPAASDQYALICYMTSPPDERQAISLFFDRHYHYEKQFLEETTMVLNTWDSELHLSFHRLVDESYKLRTGIPASSRRNIPGVANKKLMQCSMGFRFSGDFFDRYWTCYMVEHTSNGWRPGPWGEQGWQQRKVLELQLFDRILKEIVQSTKDIFDMVVHELGENRGTISFSTLSSVEYFSSSAQWQNCQQILQVVEEELADVLSTVLKWEAREKDRGQERPRWTRNDERKYRGLIGKMQGSTGRRTRDLHNYRNSIRSLKEQLISNQQQSRDNLSLIDAENVRLFTYVTVIFLPLGFAASIFSMSETPPGNVLKPMIVCSVIALFLTIVALANAKKVSMAINNYSQAKMNSNLFNLRNEIYGNEVQAPPTQQEHEEAKVGRVSEKDKRPGVPTSSQPIIHKAGFSGHVQFWIGYLFIDLPSEKVSTACGILGDPEPNHWTTYIHVIVGFMVLPILLVARLIQLFLYNAVDVGRLAWGQYKIFVTSAKPKKQDLKRNWLTDTTSIRRPLKEKVAEVTKRLSDRQVNKNEPGGDGNTGPKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USI8</accession>
    <name>A0AAD8USI8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_649935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367154.1">
        <property type="nucleotide sequence ID" value="XM_060510328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USI8"/>
    <dbReference type="GeneID" id="85394227"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="155"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="349" mass="38230" checksum="3988DDAABD62150B" modified="2024-05-29" version="1">MDRETLQKLRNMHFGGGSGGGLGGASSGGSQEVPSVVGSVNEFLDIGEGNDAFTGNRWDSVPSAQAGRPLISAPHQISPRSLQQSQPPSGYPSGYPPLQPVPPYMPVGQGPVDRLVPSDAAAMTDKREEIRKVFWPEIKSWMTSDTALQQFAAPCPKCSTSMTTAPGQKSNRAMVLVCGHILCEACIKQIANLYNLGQPKCPYCPGLIGPYSQCAQSCLDVGMMGLPLPNSMTELDKFPLTTPEGASRPSCCFTCRALRVERATNSLMRAILSETRSRAVWAPRYDHKADGKDYSDYKRVPALDNIMRQIRDIAHSDYIYQKYTWLTPTAEQKRQEAWVEMLDTGRHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USR4</accession>
    <name>A0AAD8USR4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_717272</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368192.1">
        <property type="nucleotide sequence ID" value="XM_060511935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USR4"/>
    <dbReference type="GeneID" id="85395833"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="218"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="48488" checksum="7ABFE04002051B19" modified="2024-05-29" version="1">MLAVERASLPAMASDRPDDQSEEKIEHTGPDVIQPHALIDHLLPQQLGRGVLIPLKTTLEIRQDHTIVQALITRAPSTSTNNVVNLIRSMLPEGVANNLPHLRRCAKPADIPAHLKTQFMNDSPEGRQVHTGKSTWIYIMLGEEKDFDKHGLVAKLGAIEGMDENVFLTKIPIPMVPPTSQVQAAMWTSQFWPTVYRKNNPLGPHPSMVGRSTETIKDETSLWMTLAHRVAFQAKKAGIGEPMGAVIVQREGGKSHLVAVAGDARWHQEPNRSGTGNPMGHCVLRAISMVAQKLVRHERRAAGRSNVPPILEYDTFQDLPLLEDELTVHEDEHPNADGYLCHGMEMYLTHEPCVQCSMAILHSRMGKVVFAQRMPLTGGMCSEDRGHGHPELENCGRGEGLGLFWRRELNWSLLAWEWESSDCVGPLPPVDHRVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USX9</accession>
    <name>A0AAD8USX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pal1 cell morphology protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_717466</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367890.1">
        <property type="nucleotide sequence ID" value="XM_060511951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USX9"/>
    <dbReference type="GeneID" id="85395849"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013226">
        <property type="entry name" value="Pal1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28307:SF2">
        <property type="entry name" value="PROTEIN PAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08316">
        <property type="entry name" value="Pal1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="47366" checksum="C1DA17007360CE53" modified="2024-05-29" version="1">MSTSLDNKASPTAEELFDGLTINDQKQPRPPTNRPPGVPGRENVPPGARRGPPPPGHRPSRSQEEAMRQRRLQGSGGPPRPGGAPGSPQRRPQERRPRRNSESSVLIDIEKSPTDEERKAKEARRRERERRAREGKDKDPKKPSRRIDIIDQLDATSIYGTGLFHHDGPFDAANPHRNRKGSRRAPMQAFAKDSLNMSLGGSGPLNKRPDHAVFMGHNDGEASADFATAARLAERKDDPAVFDPRARGSIVYGEESMGLGASTFLEGTPAARAAIQKTQAEQAQQSNSEGLGRSKSIAQRIRGMKREPREYGPSGRITNPEGAYTSRRSPDANGPASSISYTGERNPFFSEYGKEPETISVKRADNGTRSPGVPPPVPRRGSANGLERRATADVMSPTEDGPSKPSGGFMARVKSLKGGRRRQASDAMAPPPAPGTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT02</accession>
    <name>A0AAD8UT02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_138543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368327.1">
        <property type="nucleotide sequence ID" value="XM_060501263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT02"/>
    <dbReference type="GeneID" id="85385162"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="26464" checksum="28E67555660B945C" modified="2024-05-29" version="1">MGSALRFLLTQMRCEHVHAFSPLSAHIETILPRPVLIFPCGAWYSTFTLCSLPQTRPRDMTPRSRHIPRMFASYFQHATAFPALALCHESLRRLVAPTSCHQRRQALCRGPTRPQGIFTSKSTLPLLRGAVVGGRYYLSTRLGISRESKTPLAPPQSFQQIPGRLHLYFRSWPFALSPLFSSSSTRPPVHKAVDTMRGISQRRFETSGCCRCSALQAHLSEPPPYLSSVHLLRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT92</accession>
    <name>A0AAD8UT92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_609141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368477.1">
        <property type="nucleotide sequence ID" value="XM_060507516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT92"/>
    <dbReference type="GeneID" id="85391415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="57" mass="6228" checksum="86238B29E20BC932" modified="2024-05-29" version="1">MVRTQLCNCALGNRGGEVECGFLFEVRSDKAWSNNARSLVCCVVYCVASLRVGVFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTK8</accession>
    <name>A0AAD8UTK8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_614258</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366949.1">
        <property type="nucleotide sequence ID" value="XM_060507819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTK8"/>
    <dbReference type="GeneID" id="85391718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17017">
        <property type="entry name" value="ING_Yng1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF94">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="822"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="216"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="433"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="219"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="437"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="505"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="595"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="658"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="671"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="682"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="784"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="806"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="825"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="827"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="838"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="843"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="849"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="852"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="867"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="870"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="824"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="835"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="7">
        <location>
            <position position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1726894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="889" mass="95242" checksum="4DA081CECD3ADB77" modified="2024-05-29" version="1">MASAEEGADAMEIEVSPKNRTSVEHDIHQSLGSISNSVESLEMRADPDAQATVTDFLDFTEYLPSDMTRSLTLIGKLDQTYTEASINVHNLTSTWGKLPSIPAEERPSPVQLRADISDSLNHAVSSRVYAHAEAVRMSENVNRHYNRANTILAKLKNLLENYPAEEQKSPVATSKSQLVRAPRVMRNGDGEKVRRPRIPRITVPGEVLPPYDQFVAYSDDSDESSEEEDDESLGRTPARTTPAPRIKVVKTPKARPPKTPKAASSARPPKSAAGLTAAATPAVVLQPPPENAVIGSADAPWLQLTPWELARLRKRMKKNATWSPSDTMILRELKTLGRGIDAYKEAKKKAEDEGRVFDQVPAALAPDAEAGNKPIPEGAISAAALASDDIQLSNRGMKLNEAKKLKRESLAKQAAEEAEESARQFREAARLLMSHEASSSSAANNTNTTTTTTTNTNNNTNNNNATTPSTANNNATNTAADLPKGASKAKTPAKPKSNGNKRKRDSVPEAEAEKPEQPPVETPAPRPAPKRTKTETPVPLPHLRASLAAQPLTESTIPPPVLTPGGTAVTPKMTTPVPIPVPGQDGSATIGTGVAAAKPANTSAPASSPTGSVGPPASAASTAPASILTKLPAETPIPPPILSPKKSTTPILPPVRDSAARRETRGEMAKKSQQQQDNSTLVPAPQVPQAQRSSSAAPSIKQSSSRAATPGTTPVPDGQGRRPSSRGKAMSQEPQPSLATDRPRRASTARNTPAPEQRQQSKRTRKPVPGIVSKTNAGGSSAVGKRKAAPKKKRAQKKEKGQPIEIELEEDDEGNPIDPKEPRYCDCNRVSFGEMIACDNENCDKEWFHLECMGMTHIPARTTKWYCPDCRLRLNIGEKGEINARGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTM2</accession>
    <name>A0AAD8UTM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_614298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366964.1">
        <property type="nucleotide sequence ID" value="XM_060507825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTM2"/>
    <dbReference type="GeneID" id="85391724"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="80" mass="8778" checksum="DD38A865C861F635" modified="2024-05-29" version="1">MSIPSRGVHWISKCLKQDTVLVLQARTESFPRLKVRPRLQPGQVSCQTSRAICVRSSSACPCKPQSVSSPRSEGQRPGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVI2</accession>
    <name>A0AAD8UVI2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Family 43 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_665671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368121.1">
        <property type="nucleotide sequence ID" value="XM_060511089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVI2"/>
    <dbReference type="GeneID" id="85394988"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09000">
        <property type="entry name" value="GH43_SXA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF12">
        <property type="entry name" value="BETA-XYLOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="7">
        <location>
            <begin position="327"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="538" mass="61175" checksum="96F448D6C771F54E" modified="2024-05-29" version="1">MPQIRNPILPGFNPDPSILRVGDDYYIATSTFEWFPGVQIHHSKDLANWELVTRPLSRKSQLDMRGDPDSCGVWAPCLSHDGQKFWLVFTDVKRKDGSFKDTHNYIVSAPAIEGPWSDPFYINSSGFDPSLFHDDDGRKWFVNMMWDHRRRFHAFTGIVLQEFDPKAGKLVGPKKNIFRGTELALVEGPHLYKRNGWYYLLTAEGGTAYEHACTLARSRDLWGPYELHPQKYVITSKDAPDAALQRAGHGDIVDTPDGKTYMVHLTGRPTTEKKRCVLGRETAIQEVYWGDDDWLYVKNGPVPSLYVEVPGTRDDTLYWAEKKYTFENGLPKDFQWLRTPEPERIFSTEDGKLTLIGRESIGSWFEQALVARRQTHFSYDAETTIDFAPTDEREFAGLTAYYCRYNFFYLTVTAHEDGKRELLIQSSEASWPDSDLTMPFPEAVALPDTGKVKLALTIRGPELQFYYALEGEELKAIGPVYDASIISDECGGHQAHGSFTGAFVGVAASDLNGTARRAAFDYFTYRPVHVETDRYVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVS7</accession>
    <name>A0AAD8UVS7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stc1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_219647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367250.1">
        <property type="nucleotide sequence ID" value="XM_060501748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVS7"/>
    <dbReference type="GeneID" id="85385647"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024630">
        <property type="entry name" value="Stc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12898">
        <property type="entry name" value="Stc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stc1" evidence="2">
        <location>
            <begin position="28"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="38393" checksum="E5F41812E93B3161" modified="2024-05-29" version="1">MSSYYSSRPSGSQDLGEKLGQNMAENYRCKIGGEWKPMSGFSKKQQKLVQDKLDRHAKVNRANTGMVCRIHSGEPVNEIRCEGPCDEIKTLDQFSKNNRTNGVNICKSCQHWINTQEPGYTPWAGPNTQLDPLENSDDYASHLPTDPSEIFDFRSEVDRPLAPITGTNGLTTESDLLTRIESLGIETRQPYVAGPIGLGARDNGHASYDAIASGPGSESIASAATSAIASTTETGRDYDFHNTFLDVNFNAYDSAGKKHIKTKVPSTQSSGSSIIESRYTYEGGRPENGTNSTVVATSSVAPSGPWPGNRQRDRKQLTKEEHRALQRGKPQPQTLFNPIPYGNGDVDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVW8</accession>
    <name>A0AAD8UVW8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_608807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368714.1">
        <property type="nucleotide sequence ID" value="XM_060507495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVW8"/>
    <dbReference type="GeneID" id="85391394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="414" mass="43562" checksum="1B4E40A6F44F9AB1" modified="2024-05-29" version="1">MPGTNRTNSLRDRPRHLLSVRTLQTFDKPHLPPGAAQILLGARPRSSECHAHQLPGCPPPQPGSRVDLYLCPSLNHHPTITNLAPSHTHLALASKVRHWSRSAVVTIDNTHSSNRDPNEATRIKPRLLSSRTPEPRHLQPSPQPQPPKLLITLNFPPRQPNSRHTTNNMSLTQPTPLLLTKRLTSFLASNLNANLHTALLATPSGRLLAHASPQPVSLLRTQSTVASSLFALHASATPDIPDALPSSSSTPPSSSGAAANTIAASEDGGYHAGGAGGKPLTITVQLAAGVVVIRRLKCGLLFVCIGPLAETIEAQQASSSTDQHSHNHSHSHSQANAGANSGAGTGTPSQIPASPSEADSILSLGAQTTTSLASVGSVNTAGVVVLRRHAEELARWLDDKLGSLRVPEEGVGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXE2</accession>
    <name>A0AAD8UXE2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_717299</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368225.1">
        <property type="nucleotide sequence ID" value="XM_060511937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXE2"/>
    <dbReference type="GeneID" id="85395835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21552">
        <property type="entry name" value="VEFS-box_ctSUZ12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF0">
        <property type="entry name" value="POLYCOMB PROTEIN SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="8">
        <location>
            <begin position="650"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="460"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="708" mass="79067" checksum="7334FD5CDE8F3684" modified="2024-05-29" version="1">MTLHSRRQRSTPFLQRNILQGMGNTQSSASKAAASGDVSNGHHEVRPNKRRRMDAEHQLADQIFQARDVGDLQRNLRVQVNRIFHRASKRISVAPSDDVVNLKARCKVSLSHVTKAGEVLLYCNSQLCDIRSFKDPGGPNRMARICLQRPFYIPEDSMRINRDDNGSFDLADSYRLCVELEAAGPTFWPPININSSGDDANPTEAIHWVLAAASSDLFTRRKALLNLKVKKTPQSLGPTEHVIDIDAQWTTAFEAGQIRAVEAGTEPSITVSGMLAAQDSLLTDYGQEPLYESPPGTPVKAPRNSAVNGDVHVDEDLEEELTPNRSLRVRGATKNYNLKVLSDKAQGRDKKRKKRGAANAVEEGTVTYHLPSEKVCLDSFRCVTCGMPHGSLPQLQVHLISQHDQYEFRPQSRAKGAEFEVAHRYESYTFGPEPFALRRPTKAFDLDQFAEGNISFLTSRFGTEDQSTPGPQPLGRGSKQPLAKPAQTRSRVLLPDIGQTLYDPITRATLQPGTEYKKPPASDKWLIQWHRDALADFSDVPPDEREYMQEWDKFMLTKRLSSSIYFPAAWLSFVRLKSEWLLSSPSRMTEFGKHFTYLLARSSLDHGTVVEALDHIAMRKAKLGIKTGEYPTLVPKGSPQGPHIRKSAGGCLVCGLTVLGPRLLLCTNLKCSKRLYHSDCISENAKMSVDDPDWVCNECFETQAAERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXV4</accession>
    <name>A0AAD8UXV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_570136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368705.1">
        <property type="nucleotide sequence ID" value="XM_060504269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXV4"/>
    <dbReference type="GeneID" id="85388168"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="62834" checksum="461CCDA6D6781EBF" modified="2024-05-29" version="1">MSGSDSGTTPTDIITYIGVPLAVLGVLPILYNTIATLAARSRIRRMLRHARLTALTRSDVVNRVIEVDLPRYAVTPWDRFDHRDEYWSLARHPSSIPGGTWTTFNWRTNTIGLKTQRVEYADQLRQPQVDVTFDELISYLLDLGAVPDAHGWRLLRSTGLWTPVGCTLMQSPDGQHKALTIAPLNDSDGHLSLSVNWSSHWTTRSHESLPPYWVRLLPLPSPAATAIEQDHEKGDNDDVNAEPGKSSGSIKKKTVSPSSSVASISRAAKPNAQTPIACKISSDGLISAIPETPDHPPTSLYIEHVRIRPGHTAGTWFASAATAYGTSSATILWNYRIPDDVLAFARGSSVPCGVLEVLGVVDGSQTPEWASSHNDMRDNLDLLHRRMRDQMNAIAAEQQMDPVRREQAIRERMRKESDQHMDDVRDRMRLDSRRRETRAHEAIQSPKWDAALVATHTLPWLQQQGHFLTDDTTTVRSVAAGLLHRMLLDGAFVSALCATLDAWKAWADNGGMRKSDLEALKEGPKALEMFALASVLVAVIRDVGGAAEGSVSGDLQECLRMWRQVRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9K3</accession>
    <name>A0AAD8X9K3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_723797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000156">
        <property type="protein sequence ID" value="KAK1711629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359182.1">
        <property type="nucleotide sequence ID" value="XM_060512599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9K3"/>
    <dbReference type="GeneID" id="85396497"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000213">
        <property type="entry name" value="Carboxylic ester hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041771228" description="Carboxylic ester hydrolase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="9">
        <location>
            <begin position="35"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1711629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="580" mass="63467" checksum="0C46D1551DB7455B" modified="2024-05-29" version="1">MEISLKPALAIILFLAGQSAGNSEQHHHEPRAAAAEVETPAGTFKGRSFGSVDTFSGIPYAKPPTGPLRLRPPQRLNSSLGNFDATGTAAACPQFLLSTDSRNILLDIVGSFLTLPFFQPITGQEDCLTVTVQRPSGTPSDAMLPVLFWIFGGGFEFGSTSTYSGASFVRDGADMDRPFIFVAVNYRLGGFGFLPGREILKDGSANLGLLDQRQALEWVADNIAAFGGDPDKVTVWGESAGAISVFDQMALYNGNNSYQGRRLFRGAIMNSGSVIPADPVDCPKGQKVYDAVVKAAGCQGSASTLDCLRSVDYETYMRAATAVPGILSYEALALSYVPRPDGTALVDRPDIIAKEGRYAAVPMIIGNQEDEGTLFALFQPLVLTASQLVNYLSELYFHNASTAQLTTLVNTYDHHISAGSPFRTGIFNEIVPGFKRRAAILGDLVFTLARRSFLSVAKAKHPEVPAWSYLSSYNHGTPVLGTFHASDILQVFLGIFPTFARQSTRTYYLNFLYNLDPNVGLGGYAQWPEWSQDQQLLWFLNGRTDYLKDDFRNESYRFIYRNMQSLNFRDDSGLLPPWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9N7</accession>
    <name>A0AAD8X9N7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CCCH zinc finger DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_592755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358241.1">
        <property type="nucleotide sequence ID" value="XM_060506561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9N7"/>
    <dbReference type="GeneID" id="85390460"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057683">
        <property type="entry name" value="DUF7923"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057654">
        <property type="entry name" value="Znf-CCCH_tandem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37543:SF1">
        <property type="entry name" value="CCCH ZINC FINGER DNA BINDING PROTEIN (AFU_ORTHOLOGUE AFUA_5G12760)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25540">
        <property type="entry name" value="DUF7923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25543">
        <property type="entry name" value="zf-CCCH_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7923" evidence="2">
        <location>
            <begin position="80"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Tandem CCCH zinc finger" evidence="3">
        <location>
            <begin position="389"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1708209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="442" mass="49641" checksum="F80D028D2A2D143B" modified="2024-05-29" version="1">MSNADSQGPLSLEERWQMCKSQDDHKASLIEDLFSHIAELSDKLSEVKMELKEKKMLVRSLFDTDDKSKDQIGRLQNEKDKHCFAMILIDGDCMPFLGDLIEQGLEGGKKAASLLRLAVFDELKAIDPCLPHHLQLAVRVYANMKGLAKTYTEMGVIPDPSVLDDFVRGFNMWNAMCDFVDAGNGKECSDEKLKANFESSVSDVHCRHVLFGVSADNGYARLLGSYLDNDEIRKKIVLLEGPPFAQELAGIKDHFRVASFNRVFRRQKLVNNVKRKVSYNITPPSTPSPNYASAAAGAPSIFAGDLSVRQQVTVDPRTTLPPLGQVLRNKAGQRVDLPLDFTHQAFILMKNRKLCNSFHLLGRCPYRDSYGKCSHEHRGRLSPKELQILWAVARQSHCHTGLSCTDPNCVFGHQCPRESCNGASCRLRFPLELHNIDKRPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9R7</accession>
    <name>A0AAD8X9R7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GPR1/FUN34/yaaH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_656278</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359769.1">
        <property type="nucleotide sequence ID" value="XM_060510863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9R7"/>
    <dbReference type="GeneID" id="85394762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="32137" checksum="B4E3B2DAD84688B1" modified="2024-05-29" version="1">MATHEAHHNAVPPQDVEKDVHTSGADHYNGATNGAQVGQNTYSRQAGPFSRVADYRNMTEGEAQAFGGSLQPGVWKPYEHRKFANPAPLGLSAFALTTFVLSCVNLHARGVTAPNIAVPLAFGYGGLVQLLAGMWEMAVGNTFGATALSSYGGFWIAYGILLTPNWGIIAADGPYAANYSDHYSAVGFFLTGWFIFTTLLLLCTLRSTVVFFSLFFTLDLAFLFLACENYAANNGALTASRNLQICGGTFGMLAAFLAWYCALAGLQDDSNSFFQVPVFHLPWSDKGKEIRRAKSNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9Z5</accession>
    <name>A0AAD8X9Z5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_90396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359632.1">
        <property type="nucleotide sequence ID" value="XM_060515994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9Z5"/>
    <dbReference type="GeneID" id="85399892"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="103" mass="10861" checksum="8D30735EFD71E912" modified="2024-05-29" version="1">MALSIDVQLSSSTTGVQRSRLANAEETRSQRDVRYTMFRNDHALSVGLGFTSTRPTSQVSSTTAAVTRLNLGYGVSVRSGGAVGQPLNNVPANLRGAGSQFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAL4</accession>
    <name>A0AAD8XAL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH-quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_639073</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359261.1">
        <property type="nucleotide sequence ID" value="XM_060509400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAL4"/>
    <dbReference type="GeneID" id="85393299"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3270:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004538">
        <property type="entry name" value="PRK05888.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004539">
        <property type="entry name" value="PRK05888.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849:SF20">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="159"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="25833" checksum="AE971005DAEFD147" modified="2024-05-29" version="1">MPPAAQLPVTMLALASTRPVARNSSAAMQHVGRLMAANAMRTYATPAGPPPANFRMKKHQTWDEDQESTLNKLGRYFLLSEMARGMYILMEQFFRPPYTIYYPFEKGPISPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEERADGSRRTTKYDIDMTKCIYCGFCQESCPVDAIVESPNAEYATETREELLYNKEKLLSNGDKWEPELAAVIRADAPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAW3</accession>
    <name>A0AAD8XAW3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_43372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360517.1">
        <property type="nucleotide sequence ID" value="XM_060503066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAW3"/>
    <dbReference type="GeneID" id="85386965"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="18173" checksum="1DD12B5576AD3404" modified="2024-05-29" version="1">MAARAKFIVNIDNRAAWIPYKVICPPLKGSRPALVPSIAWPRMLPVVSPHQVRTSHSQVVATASVYPPRTSWSCRSFSLSCSQSGCVRSCQAVQRVSCLFLITIIISPKRRVGDWQGVALAETGVGCVPHLIAWLRPAAPPLYLWAPGSTHASRSRRLLLGHLQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB32</accession>
    <name>A0AAD8XB32_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360727.1">
        <property type="nucleotide sequence ID" value="XM_060512492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB32"/>
    <dbReference type="GeneID" id="85396390"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="22856" checksum="771BF7C848DA9C52" modified="2024-05-29" version="1">MSGLSTTIMPFAQLPACAVNCGPLYDANGACVPPAVAAADANTYDRCFCSQGALQAFSTAAGGVCPAAGCDDAGFSSIQGWYTSFCNSVTGGAATASSSSAGSSSTSGASKGSSNSGNGGDWLSNHWRWVVMLVILVVAIAGIWVGACIWRRRYLRRKDRMYELGKHAHKGPSGIIAGSGVNVNQAGIVNSPGQFMPGPPPAVYDEKPPKEKKKWVVSERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB59</accession>
    <name>A0AAD8XB59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_585790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361269.1">
        <property type="nucleotide sequence ID" value="XM_060505874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB59"/>
    <dbReference type="GeneID" id="85389773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00342">
        <property type="entry name" value="RHESUSRHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="44"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1718769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="54917" checksum="5A69AAF9E174D61C" modified="2024-05-29" version="1">MASPLDLENLDYVHLIPYNGSGPTGGDSLTEDLNIWYETGDIGWMITATALVLLMIPGVGFFYSGLARRKSALSLIWLSVMATAVTSFQWFFWGYSLTFSHSAGAFIGDLSNFGFKDVLGRPSVGSSRLPDLLFAIYQGMFSCITVALATGAVAERGRMLPCVIFMFIWATVIYDPIACWTWNPSGWSNKMGGLDFAGGTPVHIASGTAALAYSMMLGKRRGHGTHELNYRPHNVTHIVIGTVFLWVGWFGFNAGSALSANLRAVLAAVVTNLAACVGGITWCVLDYRLERKWSTVGFCSGVVAGLVSITPGSGYVPVWAAVPFGILGAAFANYATKLKFILRIDDALDIFAVHGIGGLVGNICTAFFAANYIAHLDGVSEIDGGWINHNWIQLGYQLADSFSGGAYSFVGTCTILFIMNMIPGLRLRATEEAEILGIDDAEIGEFAYDYVELTREVLNDMDNEAASRYSNDMASFQPMEKNNSIPLMDARNFAGSSQYPTQFGHAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB91</accession>
    <name>A0AAD8XB91_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyrate dehydrogenase-like NAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_644174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000242">
        <property type="protein sequence ID" value="KAK1705469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357625.1">
        <property type="nucleotide sequence ID" value="XM_060509734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB91"/>
    <dbReference type="GeneID" id="85393633"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="2">
        <location>
            <begin position="45"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1705469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="186" mass="19782" checksum="D325827CE702D921" modified="2024-05-29" version="1">MAAAGKLIFVTAGPESAISAISLYLNGVMARSVIPMGADVTKSSLLKIAGNIVVVSFMEVLSEAHVFAEKTGLGSPVLENMISDMFGPVLESYSKRITSGSYAPPPDSKAGFDVALAMKDLRHALTCAKDAGTKLETSEAALRHMEKAREFEAVRPLDSSSMYGAVRLEAGLNFYSDACKERDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBM2</accession>
    <name>A0AAD8XBM2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_711617</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358658.1">
        <property type="nucleotide sequence ID" value="XM_060511604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBM2"/>
    <dbReference type="GeneID" id="85395502"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1709747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="20125" checksum="2A9CA704E0BEF1FE" modified="2024-05-29" version="1">MRLYDRVPSTCTGSEGGQKDAAFILADGATLSNVIIGAGAGEGIQCQGSCNLVNVWWDKVCEDGATFRQKSGTSTVKGGGARDAPDKLFQHNGGGTVEVSDFYAKNVGQFWRSCGNCKEQTARTAIFNNIYVDGGKTVAHYNGNLGDKVTINGACVIGGATVCKNSKGVTGGGEPGDAADDPKICVQTDVKTSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDK0</accession>
    <name>A0AAD8XDK0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDP-mannose transporter</fullName>
            <shortName evidence="7">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_654040</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasmic vesicle membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362396.1">
        <property type="nucleotide sequence ID" value="XM_060510689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDK0"/>
    <dbReference type="GeneID" id="85394588"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="42524" checksum="960E68981994DE8D" modified="2024-05-29" version="1">MSDKKNEDYELRPAESFGEKDGFLARPPPRPRPALGSPISKIDNSPGAAILAYCFSSISMTVVNKYVVSGQFWNLNFLYLAVQSIVCILTIIVCKNLGMITNLAPFDTDKAKKCIGQSLQRAGFPIALLLVGMIYTGTKALQFLSVPVYTIFKNLTIIVIAYGEVLWFGGSVSPLALLSFGLMVLSSVVAAWADVQHALGGGSQSAEASAAVSTLNAGYAWMGMNVCCTAAYVLGMRKVIKKMNFKDWDTMFYNNLLTIPVLIVCTFLAEDWSSANIEKNFPVESRNSLFVGMIYSGLCAIFISYCSAWCIRVTSSTTYSVVGALNKLPIAISGLVFFDAPVTFGSVSAIVVGFISGIVYAWARIRQTEASKMSLPTTQPMSASSQSNRDANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDP0</accession>
    <name>A0AAD8XDP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_390568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363382.1">
        <property type="nucleotide sequence ID" value="XM_060502785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDP0"/>
    <dbReference type="GeneID" id="85386684"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="58" mass="6300" checksum="EEF96092F2992CD7" modified="2024-05-29" version="1">MSQSFKMTELPNKGLKINVGKSELCRNCFAHCAKSGHSTKTSESPFHCVLLDDAIVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDS9</accession>
    <name>A0AAD8XDS9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_362201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364119.1">
        <property type="nucleotide sequence ID" value="XM_060502586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDS9"/>
    <dbReference type="GeneID" id="85386485"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21713" checksum="9FBF807869B07CAC" modified="2024-05-29" version="1">MSYALSATPEKCDLQDSPRHGCANCRRAGVQCIRRDGVRKSRKMTARQRQPILPRSPTVPAVPSPPSLGTDRARDNPRMLTPARSSELTTREYQPEGFISHASVLSYDSAAEPMALHDGLPPRVMQTRDVLVKATQADTLPMPSLRKALTDAFFEFAFLTFPSLMRKTSRWESRRSFYSKLCASLAVLCVMTPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE95</accession>
    <name>A0AAD8XE95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_395838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363176.1">
        <property type="nucleotide sequence ID" value="XM_060502819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE95"/>
    <dbReference type="GeneID" id="85386718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="12630" checksum="BEB28F8D1277A4F7" modified="2024-05-29" version="1">MILTCESATGPTNICNQLGIVNTSKTILPPPPRRLVDAIAWRIRTFARSLLARLHEPSRCRHKRRSLIILRDSLPESYAARFRSNHQPFRIHPRTLRSEYKFPRMCDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEV2</accession>
    <name>A0AAD8XEV2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helix-turn-helix-domain containing protein type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_577177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365244.1">
        <property type="nucleotide sequence ID" value="XM_060504994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEV2"/>
    <dbReference type="GeneID" id="85388893"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="entry name" value="dinb family like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="BLL2446 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922:SF1">
        <property type="entry name" value="DUF1993 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="18843" checksum="38D86C71236C7E81" modified="2024-05-29" version="1">MASVTVYDAVIPTFTKGLKTFDHILTKAEEHAKANNVDVNTYPEARLVEDQLPLTFQVQNATKTVKTNISRLTGVELEPYENTEKTIADLHKRIKDALDLLSKVDAATVNAKADSQVDLPIFGGKTLKVTAKEAALSHGVPNFFFHLNAGYAILRSKGVPVGKADYLGSFVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG43</accession>
    <name>A0AAD8XG43_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAUS augmin-like complex subunit 6 N-terminus-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_626152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363578.1">
        <property type="nucleotide sequence ID" value="XM_060508545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG43"/>
    <dbReference type="GeneID" id="85392444"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="742" mass="83673" checksum="BA55750C5047F381" modified="2024-05-29" version="1">MATLPANSLLARSRQPRPGPSTKTLSAPLNASISPSIAPTTNASLFLTNLRLLDFPSFSDWPDFDAQTFSVQKKRIHCVEWTLYQLFVLWDPEEARNKLQPFFPPRDHVQSMNLRAALLRSLDQAKKNGVLGRDAVVRKTMLDECKGERLEEVLAVFSSAVLKKMVAEVAEAEHEYPAIAQQVALENRGYSAERTELVTLALAHRASITNAMRKKNEARKRYRDLAEVLSQKEKGIARRKEEIKSARELTSARNLPDNLRSDTWRTLRTNWAGNEKWMETLLYGDSNARKDGLLSAPFDRVWRRLESGRLTELETHDTGLLEQLDDRVRTQRERLARWQEFRADMFGERRKASTSKTSQPTRTKRGIDLEFDSHESLHLGRTSPKRQLAKKSTSLTRKYSNLLDDCLAELAEVGSLPVVKLTETLGPRTRHHEKPDGILATRESLGDETISELSELEDDLHGTNNLPRRPSLQEPHLRRLERPAINISSRTSSSDLPAPLPSPLLLPPESPDELAIPPPTPPLPDEDDITETVPNRIATPPLGEEGEAEVPFGREESSPEPPKSPTQELADQILKDMDVTSPSPVKRSKPRHTLSLSERTRLSMARSSRSVKYDPDDEEDDTLTLRPSFASANRRTGEVTIRVTDEGDLVARTRKSMVRFEAAHQKAQLDRQKSLKKSRPRARTESQIPVVEEETMGLDPDASILAEELMAVEDMEAVFRSRPRIKTSPAPSPSRKPLEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGF1</accession>
    <name>A0AAD8XGF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_270333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366337.1">
        <property type="nucleotide sequence ID" value="XM_060502046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGF1"/>
    <dbReference type="GeneID" id="85385945"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="386" mass="40568" checksum="C7E1721A8FF0EF0C" modified="2024-05-29" version="1" fragment="single">MERSRGLPDAELFLHKPAEEDCDSPTVEPLRIFKPQSPNPANDRFKYPAPPSASGSSSFTSKPTFPLPPGASSSAAPLPYPDEEDLRPGKPTKPTITAPKRFGSDYNDTTPRFNATSPVETKSPTLAERRGTGPRPLGATSPQSPAGDDGGLFAKPLTAPQPQRPAASTTNYPSYTKKPYYPPPGGASSSTPPAQSQSQYQARPPSQSAQSTDHLEMPGQNSVNRFASTASTSTTRASRGSPPPPETPIVEPGVIPGGGIEARYAASGISGTATLTSLQAQQAQSAAASQRLAQYGGAPPPARPWTPTENPENQPHGPPTVYQGMNPVTSPTQPTFSPPPQQAENQGEQTNLQVSVLEQDYQRLGLNDPPPAYSSVTPSGNPSYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGT5</accession>
    <name>A0AAD8XGT5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_752783</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364343.1">
        <property type="nucleotide sequence ID" value="XM_060514251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGT5"/>
    <dbReference type="GeneID" id="85398149"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000474">
        <property type="entry name" value="Sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF14">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="548"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="119"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="633" mass="70049" checksum="E03FD789CEAB30AE" modified="2024-05-29" version="1">MTSLPPEKDGPVSKSSLEAGNAVEISHHDHPRRSESQTATGEPRNPLEGIPREQLKIDARLFAIGLGLQNEIAYFEKGALAAQTPKAYEDIPELTEDDRVVLRNEIEHRWRHPKALYFTILMNSVSAAIQGWDQTGSNGANLSFPQAFGIADKGEACRIAGTCARNSWIIGAINSAPYMAICVIACWLSDPVNSWFGRRGAIFLGAIFSILGPVGQALCQTWPQILICRILLGMGMGLKEVTVPVFSAENSPPNIRGALVMSWQLFSAFGIMLGFLANLAVVGFGDIAWRLQLGSAMIPAVPLLLGIYFTPESPRWLLKKLRFIQAYESLLRLRGNNLLAARDLYFVNAQLQKEQELVEADGLGDSSFFTRCVELFTIPRIRRATQASGIIMAAQQFCGVNLMSSYSSTLFEEAGASSTVALLASWGYGMAMFLFAIPALWTIDRWGRRALLLVTFPNMCWAMLAAGMAFYIPQSSPAHLGVICLFIYIFAAFYGPGEGPVTFVYSAEVFPLSHREVGMAWAVATNNFWAIVVAQTSPPLLQGIKPQGVFTLYSVFGVICLILIFLLLPETKQRSLEELDHVFSVSTRRHASYQLLEVLPWWLKRYIMREGDKPEPTLYLFEVEENVESGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI26</accession>
    <name>A0AAD8XI26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_217948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367211.1">
        <property type="nucleotide sequence ID" value="XM_060501745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI26"/>
    <dbReference type="GeneID" id="85385644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="95" mass="10291" checksum="224E575C40D61E00" modified="2024-05-29" version="1">MRTYRTPYLSPYLALLSTVPRNPIVTFPSASPLTSPWSPSAPTAQPTSLILPQALHHVVGRTITPQFLISFPSPSSLNTQGTRYFSLLSTAPALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIJ7</accession>
    <name>A0AAD8XIJ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368752.1">
        <property type="nucleotide sequence ID" value="XM_060510174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIJ7"/>
    <dbReference type="GeneID" id="85394073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917991" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15729" checksum="DE169E7270E1AB2A" modified="2024-05-29" version="1">MVAQKAWHICTFHTLLFIRWSVGFHFETIRVAQADHILAYGVSVQRTVSVVRLVESGPAGFHCERVFRGEPALLDGNRKSGWDVRRMDGGPLAPSEAVERRHIRQEVNVVGQERIECQTLLDERDGGTRIADNLARHDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ56</accession>
    <name>A0AAD8XJ56_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SPT2 chromatin protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_576072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365710.1">
        <property type="nucleotide sequence ID" value="XM_060504886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ56"/>
    <dbReference type="GeneID" id="85388785"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="42997" checksum="2D4C808D9860E87F" modified="2024-05-29" version="1">MGGSQIGDLLAQISGDKSQSTSPAPSRPPLPPSKRKADDDLRSTVSNKLPRTSTNGASSSAPPRSADAQRPARPAEKSSATTTGYRGSAGRPSDRSTSAPRPVGNGTTSAKSSSAGARPVNGSGTSRVTSTLPSRPSPSAPVAAPKGAPPKKGSFAEIMARAQQAQTKLGQVGKIQHKPVEKVFTKKEREEMKKDYKKDSKGAARPASKFQGTSRPSSAPPSRNGVSAIGSSASRNGTADRARDPRAGVKARAAAAEEEQQKKLKKAAVATTGYTGTARPKPGATSAKKKPAPGGALLNSRPAPRYGGSAKRSRYDEEEEEEFDDFIEYDEDEEDDRGPRYHYDSDGSSDMEAGMDDVWDEEAAAERAARREDIEQERLEKRLKAEKEERKRRFYEEQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJH6</accession>
    <name>A0AAD8XJH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_570957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368183.1">
        <property type="nucleotide sequence ID" value="XM_060504361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJH6"/>
    <dbReference type="GeneID" id="85388260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="422" mass="45329" checksum="AFEA305AA5CC089C" modified="2024-05-29" version="1">MLTTSPIVASSANASPNSFHYAPTRSSPHSSPARLSAPLPRRHSASRSSPSAASMTSPSSQPRPRQYVAVDAGTQYSPMESSTQKAQDATASRTPTTVPATPVEPPPTPRPQPIDPSAPQPQPQPEPHQRSQTEIQSQPQTVVAPVIREASTTTASPGKRRNSQDPAVAQAQASASAAGESSSGAAKRPKPTAGPPKILPQRYELCSTEDMVVLISHMLSELIETNDALALRSGSLTRFHSRTAPSISVLEYLNRLAKHATLTPPLLLSMVYYIDRLCALYPEFTINTLTVHRFLITAATVAAKGLSDLFWNNTTYARVGGVRVAELKLLELEFLYRVDWKIVPNPEVLVAYYRGLVERCPGYALQEEEAEAIDEDEDSDEVEDDGSTEISDGVADDSGDSPDEESPAKSSHGDEAGPSQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJQ7</accession>
    <name>A0AAD8XJQ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_648410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368798.1">
        <property type="nucleotide sequence ID" value="XM_060510178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85394077"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14210">
        <property type="entry name" value="PKc_DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000112">
        <property type="entry name" value="Putative dual specificity tyrosine-phosphorylation-regulated kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="926"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1228"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1327"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="610"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1281"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="955"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1346" mass="145800" checksum="188D077359EE3F39" modified="2024-05-29" version="1">MLSASSANNHPLFSFGRNGAANEVADSTPSYDFLPSVSFDDLQSSLESASHDFKLTQFPNPTGQGGILDSESMADKMGGVSNISQSGASARGGIPPPVTRPGRSGSILRRPSTSSRQPSISSIASGPSSSVTDASTAAARSRRQSHYPPVSNTNIAKPPRKSIGPGVIETDFGSNTAQRRRPSLMGTAGSGTDFSRTSMDAGAGMGFETPRNLANSRATKAKSMHQPLPRSNTANLSTPDNTRLSTISPRSPRGGSKGTNNGSAQSKRQSMMPGGQHASHASGLGARTISPTDTRRLKRMSMHQTPSLNQAANAPPPPPLEHREHSRSPSMIPRKTSATPSSSRTTPDINRKSYSSGLSITSTNSFNTVRTSTGSIQPRAPVAGGTTSRLPAPKSSNPHNHNPHSADDEEDVPPVPAIPKAYESPQQSATEASFLDKRKANLAADASSINSNSTGSFSIPSLPEPAVKVARKASTRKSTNAAPLDTEKKGNAPQSRKNPPPVRLPPITVGPLNSSTTAKIAALGQNGADRNLSPPPSRIIAKTPTTPMTASKSSFFSRNRQDDKSDFPNLRSSSTVHHSRIDSASGADGTSSSESFAGVPIPVPYKATRKPSVSPFLSSSVPKPGADPAFLKRSQTGDLGNITETLEVKPPQKPSGPRAQRPVKAKSPTPPISDPEEPPTPSSMSSLRRKLSLSWKRNTSKTDSKASTSEKTVERSISKEQMPPPRLPISATVGNLSSAKNSPSPSVKANNSYLESRRRKSSAASLGHDRTKSENWTSASVPKTVNDPHNPSVMQKILRPKASATTMRHHDPWTAELDKDDLVAEEEMKKMGSRRKETEIAARTLDALRKRATPKERVGAQEAIRIAMLNIYERGEIVDYNDVYFCGTQNARKVVGDLQSEAPNFGYDDERGDYTIVPGDHLSYRYEIIDVLGKGSFGQVVRCIDHKTGVLVAVKIIRNKKRFHQQALVEVNILQKLREWDPKNRHSMVNFTHSFYFRGHLCISTELLDMNLYEFIKANAFRGFSLKLIRRMTKQMLSSLNLLKQHKVIHCDLKPENILLRHPLHSEIKVIDFGSSCFENEKVYTYIQSRFYRSPEVILGMTYGMPIDMWSLGCILAELYTGVPIFPGENEQEQLACIMEVFGPPEKHLIEKSTRKKLFFDSMGKPRLTVSSKGRRRRPSSKTLQQVLKCDDEAFLDFLARCLRWDPDRRLKPEEAIHHEFISGKKMTAPLPRVPTTREASPVKRHTVGAPRPLPEPPASGLKSGIRSRDVSGASPHKPVSTASSRRPSVATSGTVHVATAKRTSTGQGGVTIGTSSLPRAAIRSVSAKQDLASAGATAAMSRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJS0</accession>
    <name>A0AAD8XJS0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_572666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367390.1">
        <property type="nucleotide sequence ID" value="XM_060504535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388434"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000136">
        <property type="entry name" value="Ubiquitin C-terminal hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021905">
        <property type="entry name" value="DUF3517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF827">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12030">
        <property type="entry name" value="DUF3517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="1631"/>
            <end position="1956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2568" mass="289242" checksum="4701F20ECA4AD453" modified="2024-05-29" version="1">MDLPTGSSEAPDRAVSSEPSSTRPNPFIDGDDSSRKRRRTSMSGGSRSLSVDSTKLSTDTSSSPAANHPDEAATQDSAMKIDTHSSTPQTPERQSTAREPPTEPSSSRVTINLRNATQPDPLSSSPVSPTPRTIPDQATEPSQGVKKSVEDLDEVDMAQAPIEITDTPPSSSSSPQSPEVEVVAITDDDQDAPYDDDVSVIREDAASFDPTPDFPYHEAHESLPDTVTKLVQYLSSQAPPEEAVLESLCAWMVSYVKYVGLVGGRVAYESQVAYHTFWHMFPEIAWALATRKHPIPLETRQTIGQFFHAYARMTAHFVEFDFITAQAFQMSPGDERRQPEFLLFRFLQPLTSFAKREHSRAQNGQTPDEELLSTDMLNTFQAGIGGIKGLIKLAQMHLSNAPRYQHLMDVLAPICSVAAHILQKVVQGIHREASPQSLEMAKVRVADGHLLYNLASNAFSATIENKVTQLSNDTTTNLIHSLSEVFKICLNGEHRLATERLKAYQQKHPELPPRFIPEAISLEWRLGIYGKLITSSQMQLRVLAASNMCHDLVTCWKRYSDNEDEECKQFLNYVAEYLLRTKLVDYILGPTCHPEITVESGNIVGFLVVTRLYRSGQTDLLWQTITTAQDPRVSEALIRMTTGITNLFSKEELHYLCEKMQTLPVENFTTSLRGLCDQSLKSLQHKTQIAGESQSVLPLSICIRLLRESSIYVSDSVVAYPDVHHFAMTKFRELVRDGIEPEVRKEIYLDCIKDIAAKTPTTLGTLSCLSMALRPAVASELRTLTTDHNLTSLLIDELEHAIEQGKQNGIRRTLGGAVNHSRRDLIANILAYEPSTVTSDLGPRLWGMLVGHGAAGQDDRDDGWKILNSLPKTAFGNPFLSVCFSDYLPNLPRDCLCGGALEFVRNAVLPRVNDINDIILDDVESLAQSGVEQLWRMILDAEDGVMVAKDLLFVDAAIQTLVGDIYVDSKSIMAYPHHRACQVHLGLVNRCLEQMLDAAKRLEAFDGSKPSDDKSMAIISTEEQTLEQERTFSRSLAVLRHFMKAHQAKDHFSAPDLRALTPGSPSIAEGESAELKVQSFDGTKQTDIIPLEVGRQNTAASLLASIRQATGFENYRIYYRGHPFAPNENTVCQSLEDLKIHDGLILVKREENGTAMASRIKPGASLLEIEILGHFEQLWDYLSMKEAIATEMHTFLTGLPADTHMLATFDSPDTSYRQVFPSGQPFKSLYALYAMTEYIGAAVRRLNEATVTLTDAVDADIDAYLDALVRVRALVVAAISDREILGDCASGALQNRLTYNLMNVYGLTFRDPDIEELVVRPKPVAMAPADRLVEILRSAVSAPSHNGLVPLIASTFSAILRSAAVDSTFWMSLKALPDLEELMGILLLDEPSDAIRANVAKLLEERVIMPYEYVLHTGEHLPSSDTSNRSNTNTNSFCAFLWPMLHRLILRAAESPRQCQQVFDLSLALLREMAFDEAAVVDIPVLASDCGRLLLEHDSTERLGQAGTEDAVANGLVKLIQSCLDEGSDVYLESSLPADLGRKLFWRHLFPQPGQHSLSSIRNFLLSTNTRGILAEIVFDLVRDRDFEFLALLEALESLVPFDEFDNDPYLYELQPSFDRMSAVRAPCGYAGLRNLSNTCYLNSLFTQLFMNTGFRRFMMNARIPAQSNTHGLLRETRKLFAFMQESSRKFIDPSLLVGSIKTYEETVIDIHNQMDVDEFYNLLFDRWEGQLSTAEDRKTLRSFYGGQLVQQVASKECEHVSDRLEPFSAIQCDIKGKSTLQDSLQAYVDGEIMEGDNKYKCSSCDRHVDAVKRACLKDIPDNLIFHLKRFDFNLRTLMRSKINDYFSFPTKIDMRPYTVGHLDSPSEPGEEDMFELVGVLVHAGTAESGHYYSYIRERPTAASSEAWFEFNDDLVTPWDPVKMEESTFGGTDGSLETGIAYDKTYSAYMLFYQRSSVLKAEQEKLQPQSIPTPLKVEVPLEVIDHINGENTLLLRRHCLYDPNHSKFVLRMFQHAMMRNGGKCSDTHVVEQHAMFMFLGHLDQVASRTKDLPDFEEYRDEIEHAIVNCANCAADFFDYFQERHEAFRQLLQRNPDPAIRYSIGSLFLTALRQIKISRPEMWGLSQDELVEDPVIMQCVQLLEALWNNFHANIRSWPEVFQTILAFAQLGTLETAVLMAENWFYRVLRIVFADANMDLPSNYARMLTNVIRRISNTRSTSYEMIIQLIDHFMDALEDVLDVHTIVESAEMRLDIYMEHQAPKMSWTPEEINVLTHEWKQDAGSTFVKKLIDIDQEPTYTTSIIKRIINLSHDMDNRVFTLLRNTITGGAVQYSNAPYIRAAAIYSHESRNTANIQTLFRTIAFQCRALQNTDGQAFLDFFRLAFVHLQNEREEIRVIRYPQYFEFIPMWAPPLLGYYDADVRQGTETLLYMWFENHDLNDDEDDSLAVIMNATARKLAMSCLVYLQESFVKRRAQVAKHSTEHLQAIIAKCEPFFGVDLGLENDRLISFAEYQNLYHSVLEPLRRMTVEELEDEGSDWENSCGSSEQLESIADISMQAAGDLPEADLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK35</accession>
    <name>A0AAD8XK35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_608313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368879.1">
        <property type="nucleotide sequence ID" value="XM_060507472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK35"/>
    <dbReference type="GeneID" id="85391371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="307" mass="34437" checksum="EB35B172D828906A" modified="2024-05-29" version="1">MQSLEESDNFLIDHVLEAVDDMTDSKQPKVLLFDIGGVCVVSPFQSILDYELSLGIPPGWVNYSISKTSPKGFWHRLETGSIPMNQAFFEGFTKDLHDQVRWEAFYAAQTAKNPSLPKETPPLPTVDAKYLFNTMMVNSIPPDPWMYPALKKLKASGKYILAALSNTVIFPEGHKLHRKDFMDDPVRSLFDVFVSSAHAGLRKPDPRMYHLALERLNEYAAQNASSERGQALKWSEGIKPQDIVFLDDIGENLKEARKQGFNTIKVHLGRAYEAVEELEKVTGLVLEGDHPKVPVKPNLKGSGKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK69</accession>
    <name>A0AAD8XK69_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_569534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368937.1">
        <property type="nucleotide sequence ID" value="XM_060504208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK69"/>
    <dbReference type="GeneID" id="85388107"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="282" mass="29336" checksum="AE109BDBED8F5CDF" modified="2024-05-29" version="1">MATTQHQYDEGPELAPQHQYPEVYHPPPQQSYSASPQPEPVTPMKQEGSTYGYPASGVDQSVYGGNQYQNAAGETGAAPQKNRKTVCGCTFLVFLLSVIIAVLAAAVIGLAAGTGVEASRANNAIQELAAMSASATSGGTTATTTVTVTSASATATGFNALTNGCTDSSETTTGQTYTTDFFGKKTFTMYCNKNAPNSPLMSLFTANFDNCMDACASFTNYEPGFEGNASCTGVSFIPLWTTRAGAVEGKAPGNCYLKPGNQTKGNLETPNIGTECHAAIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKK6</accession>
    <name>A0AAD8XKK6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_568928</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. eL40 is essential for translation of a subset of cellular transcripts, including stress response transcripts, such as DDR2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369142.1">
        <property type="nucleotide sequence ID" value="XM_060504133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKK6"/>
    <dbReference type="GeneID" id="85388032"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.50:FF:000001">
        <property type="entry name" value="ubiquitin-60S ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="Ribosomal_eL40_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="126" mass="14311" checksum="93DADA476CE64005" modified="2024-05-29" version="1" fragment="single">SFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKFNCDKMICRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLM7</accession>
    <name>A0AAD8XLM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_716142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369691.1">
        <property type="nucleotide sequence ID" value="XM_060511821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLM7"/>
    <dbReference type="GeneID" id="85395719"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="35322" checksum="510C8A3B51588010" modified="2024-05-29" version="1">MAIDKPTQEKFFEVRSPASFAARMWSRNYSGVPVVPDGDVILVVGLGEETTELRVDSLILKRASRVFGAMLGPRFSEGQKLLDRGSEPVKISLPDEDPEIMELILNILHHQNSRVCQIAAADSILEVAVVADKYDLIDALKYASQTMLHYHEPSIDHLTVGDLWRLGLAAGLLNEAKSFEKITRMLVWNHTVPYIQLVDAEDVVDIEFALRMCYLLEKERQDLKTSLLMHLLPIISTGNQLRLVEIKVDSVEHFDAWPELMKLFGASLKETTKFAEGLVLADRSRRAAGPSSDFMRHFKARGGIRLADARRGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM42</accession>
    <name>A0AAD8XM42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_716004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369883.1">
        <property type="nucleotide sequence ID" value="XM_060511807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM42"/>
    <dbReference type="GeneID" id="85395705"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029164">
        <property type="entry name" value="PIG-Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400:SF1">
        <property type="entry name" value="PIG-P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400">
        <property type="entry name" value="YALI0E29227P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15159">
        <property type="entry name" value="PIG-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="360" mass="39774" checksum="1477C1237F7280ED" modified="2024-05-29" version="1">MDHTAADGDNGAEKAVSPKSVSLSEHQYQQQHPPSTVPHRRTSSGANFFSKLPFMRSHSDGKQQQRHQEAEDDTPRSPPTSMSTVIQQQQQQQKSRRRKGSLRKVALLGRGAQRERKEAKQLTIDTSHTVSRDMEGAASRSHATAIEHDPLGLNIADLTPRPSMEGYASRSSLVESPVPSLSNARQTNEAESTITSPTISYTSTTDEDDVLHIPNHTPSHLQPDSSLSSGSESYFGTRPRQQSILQAKSPLSYSGLSTTPLPPNDTEIDYSDTEWWGWVVLIVTGLVFVMGMGSVFGVWSWAWDVGTTPYAPPELEDDPTLPITGYYPALIILTSIMAWVWVSVAWMGMKYFRHAKISGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMU4</accession>
    <name>A0AAD8XMU4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_602077</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370304.1">
        <property type="nucleotide sequence ID" value="XM_060507145.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85391044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1030:FF:000008">
        <property type="entry name" value="Protein transport protein sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024468">
        <property type="entry name" value="Sec16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12935">
        <property type="entry name" value="Sec16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 N-terminal" evidence="14">
        <location>
            <begin position="224"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 central conserved" evidence="13">
        <location>
            <begin position="938"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="12">
        <location>
            <begin position="1117"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="330"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1423"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="833"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="865"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1448"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1493"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1567"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1600"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1641"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1686"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1709"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1737"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1828"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1879"/>
            <end position="1889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1912"/>
            <end position="1921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1730249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1929" mass="205468" checksum="4FF70FDA4AB71C93" modified="2024-05-29" version="1">MDSTANASWHPAFMPNDASGHATTETPVSSSAETHDSPSAPAPWLAEDDSQDASDDWPVFERPVSDAPAETDDGPKEASISTPAAEPGSNSFPYTEPANDTAPQPQAVADEPKPSAPTLGHTSTNSFTRTVSHEVNWDDDHDTEWTLSRPDTDPFKFMPPNERTNSFPPVPPASGVSAAVPGTEQPLPSNQAEDLIQEIESAPEHFDNGAFEETKQVANDFENGFDDEEPQDDQHYVGRDATFTEQEDLGSRYEEGVPLIPHSESNGELSQPEQKLASFGNEVAGEDDFFSQIQNSNNEDFPDFSGNHPLERKSTMQVMGDMNTNTLSRADTLGEMLEEDEDVDETTKSMEEPAEPVQSEDSGAKPSDDLAAKWEQALADDDGEDFLLDESLDEAGESKTVDPSAFFGSDDEGFLDDDDDDLPATAAPAPAVQSAGQQNRYTPAVASHQASSSPYTPTAPYQPQNAATPFAPAVAPYAAQRTQSATPYNAQQTRPEPVKAQSFAAQSKGGYTSPYDLPMEVVVPKKRASTNQLPQSPSTGPSSGPPPRSSSMQAPTPPPPPRAATSSASPPTSNHSGQPPPAGKPVPMLRNKDSFFEELPMASKPRSASRQSYRVGSPALAGPPEPLQPQNPGQLAPSPLSPPMLSPPGMNRSLSGGIPHLVPGERVNPYAPQTTQQQVPGIPGNARYSPAPPSAPSANGTNRPPSASRYSPAPTAARPPVPAFHAATTPPTVLPHLPRTSSPLAHFEVSREAAATNGDHPQPDRRSSYSLEPKRVPSLPTTREVEEEDDSKTSYAAQPANGVPAESRYSPAPSMVARQTPPPSSHGPPMHSTLSPSKRSTSNYLPQAALHDSPPDNRYAPPPRSQTQSPGSSQGARPQSQPVPRPTSVHSPTSPRATRSFQPVNAPLSRPRGPSQTFNWVAPTDGRENDSLQRWKGAPIISWGVGGTMVTSFPKNVPRYGMGQTAPMIIRSPGEVHVKHIKDTQPLEERLAKFPGPLRGKSKKKETIAWLSSGIETLEKELPEVSFQPQLSHEHKRAIERLLLWKILRIFVEHDGVLEGTTAVDKAVRDVLAPGLDANANEGTLGYGAGLGADALQESSSTQMKAEVVDSSTMDQIRKHLLVGDREKAVWEAADKRLWGHAMLISNTVSPDLYKQVAQEFVRKEVNYPGHANESIAALYKVLSGNFDDCVDELVPAHARAGFQLVNTTSASGSTKDATEGLDKWRETLGLVLSNRSTDDIRALNALGNLLSSYGRAEAAHICFLFARKATVFGGLDDPASNFVLVGADHKTQGEQFAKETEALLLSEVYEYGLSLAGGPTLTVGVPHLAAYKLQHAMTLAEYGLRDKALQYCEAIAGSINAQTKRSNYHHPILETAVENLRTRLRQAPKEESSSWISKPSMNKVSDTVWSRFNKFVAGDENDGSAAGASGEGGAESGPFARLAGGTPTISRSPSVSNFEPMYGTGATSLPVGSPPAVPIPTTRAASRYAPGPSQTPLSSSYEPGAGYTPGPASVGRSSNEYSRSPYEPRTSMESQPGYFNGGYMPQHATAPSQGYTPPMYGGGQDTAASAQSLPGAVQNSPMQSPTKPAYQGYEPYGSQAPTVPSVEVQSQEAAENSQQPDNNLASPGYQPPSYGYEPPSMSNGEPQSQSAEPTEGGGYEPPTFQPYGYEPPSYNPEPEQDDEGESRPKPKSFMDDDDDDIPALKALKPQEKGKSEKDKENEEMFKKAAEEDAKRAAAQQQSKKGWGFGSWFGGKKEASPDPQQQGNKPVKANLGESSSFVYDPDLKRWVNKKGGAEATQAKTATPPPPKGASRSNTGTPPPPRTMTPPIGRASAPPGGPPGPALAHAASNESLGVPPGPRPPSMMRSVSNNSVGGPPSAPPSAPPSRPATSMSNASSIDDLISAAGPRKPGAKKAKKGGRYVDVMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPH6</accession>
    <name>A0AAD8XPH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mis12-Mtw1 protein family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_565362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371107.1">
        <property type="nucleotide sequence ID" value="XM_060503745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPH6"/>
    <dbReference type="GeneID" id="85387644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="56450" checksum="B4860F46C5D62FAA" modified="2024-05-29" version="1">MTTVIRTRHPLQVISMSNEQPERRKSKRLAASSVYDEQDGDFHFTRGSKSKRVKNAEPEPEPEPELEPEPAPLPPKKSGRGRPAKGRSSAAAKAPEPEPSVVVPKAATSSKPRTRRTASTQPVEDDELQLFAPKRTTSRSTRSSTGKTEKAKPARKPEPVPEEGEEEEEHDGVNSATPREPEPNRRRTPLAIEEPVESAKITLPVSDTPVINRNKEMRKKGGGNRRSSTGMRGRRASSLIESGHNAIPHREVETAEFYKHIESEGLMEPRRMKQLLTWCGERALLQKPPHGQTDSNTVLGARYIQEQLLKDFSTKSEFSDWFSREEEGPKKPVVYLPNPRNLEHQEKIEQLEQKVKRLKLEKKKWLALNKPRPDIPPLFSETDRAQTATVVDASILEPNEAEMLNWLTHPASSFENVRAKTLARLQNTQSTLEFKVDQLADGIHKLSQRVDTAGREADKVLSLSAARLKEREAREKANAGTKEMPVMEVLRSLGRILPEDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ66</accession>
    <name>A0AAD8XQ66_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_599141</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371458.1">
        <property type="nucleotide sequence ID" value="XM_060506978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ66"/>
    <dbReference type="GeneID" id="85390877"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000173">
        <property type="entry name" value="Mitochondrial 54S ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="137" mass="15148" checksum="1F8CB7BF87411B18" modified="2024-05-29" version="1">MTIRALKTVSTGRNGLGSFILQCKKLDFHYCDWAGSSKGMNGFIKSQLPKFAAANPQVEFTVSPRPSKHPIIVGHYINGREKAICVRNMEPIEILKKAELLRDANGEKLKRVNKPVNSISPSVRGVWSPYHGNGMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQN6</accession>
    <name>A0AAD8XQN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_564387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371834.1">
        <property type="nucleotide sequence ID" value="XM_060503636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQN6"/>
    <dbReference type="GeneID" id="85387535"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="37970" checksum="F244769457D44D0A" modified="2024-05-29" version="1" fragment="single">MPSSLKVPESGLILESSAASGNPVPPQAFCINLSDHVLEDMIKCVQGGEDLQLSLGSSPTLLYGSSSHTLSPISATFSHDLFLTKPFESTKRATRLPQTSSLWKRLPGSEAPKKGEQAKAKGAPSTSSSGMDSDIENLQNSIAAATASKKQSKVMDRPLPGTNKKATGKTAKSKLLSSMASYGNGGGKSSPSGSPALVAVSSPSINPVYASSQQIVEKSKEQRSMIVHELAVQERPADYLESLWEGKYEDFKPALEKVAQFEPDTQMWALRKNYWRELDVWKYEYDTQDTRQKAIDNAIRQFDKMRLATTETEWQKLLPREERGKGKILSKLQANIAKASAAPPPKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQW2</accession>
    <name>A0AAD8XQW2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_8456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371939.1">
        <property type="nucleotide sequence ID" value="XM_060515952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQW2"/>
    <dbReference type="GeneID" id="85399850"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="147" mass="16186" checksum="C3357405EDEA6041" modified="2024-05-29" version="1">MAWPISNSLLYTLAHRALLQVHVAAVVNIIFFAHFPTARYCQHRHRPRFFFCSRFSPHFRSRHHRICGLIIALLARVPTFQIPSLPVTQASLGPTSHLVQVSSALVEADRPVSPILSILSGHPTAPAACARTCSSKPPSPSKLPLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQW6</accession>
    <name>A0AAD8XQW6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_714829</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371905.1">
        <property type="nucleotide sequence ID" value="XM_060511674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQW6"/>
    <dbReference type="GeneID" id="85395572"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="66445" checksum="7FC0E84A4316E8B3" modified="2024-05-29" version="1">MELTPNTSPREANSPGDTQQRAGAAKSKATIRASLACVPCRSKHVKCDSALPTCLRCRLEEKTCYYAKSRRGIRDAKKRSLINDPIAPPSVSPDSPVSFPSPEVASFDIPIHVVDKLPYGWSLARSSHLPDLNTASPTSLLFDLYFTNFHDTHPWLLPRHQLLSRIRSNPDPFHFLTSCITYVGSLYSNAVSSEELREKAFSLASGSLPMTCWTVQGLLVLSVAAFGEGRLDLCAGWMDAATQMALDLGMQDKSFADAAGDPFVAESSRRTYWALYWQGNMRAMREDSPTFMLSGVVATTELPCEEWEYQSGEIPQPLSLKKYNARDPMDERSYSSWTYLIDLCRLSTELILPMPTLPLGLLTETIDRADSRLVSWLINLPKWKQQLVDSGGAVDMVLFHAMAYAHSLRIKMQLPMEASGFGIRDLLTLGPLFKARNMPFPRMPRCSSSSYPWLECSTALQAGLATIGLFNFSLPPARYSPACIIGLRRAALALLDARMYGGSDSPALREKLDLLLGVLKVAGEMWPIAKSVGNEVSEVLRELNVTSNRDSVTQLDSCMDAFITDMSTSAVAPDSDVFSFPEPRTVEEMFNWSTGIANMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D016</accession>
    <name>A0AAD9D016_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_13097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369708.1">
        <property type="nucleotide sequence ID" value="XM_060501212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D016"/>
    <dbReference type="GeneID" id="85385111"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="206" mass="23175" checksum="DE3723DDFDB00DFA" modified="2024-05-29" version="1">MRRLYRLYSVPTAPRSWADAFWWEWEWTTFFFFFFFWVCWAGRHPRRAPSTCPHLTRGPPPFQPGQPSGVEVWHREVVPPSSTPPFTTHHLPPTPSPSTPQGLCWSPTMDQKARQSESISPAKREISSSKYTTDTSPMTDAKTSEPHRSLSPGPCSSVGRSILTTSRPPCDGNPQTKPFSNIPCVFHPTGLHSLRPYGEGGGLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0D5</accession>
    <name>A0AAD9D0D5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium-activated chloride channel-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_569033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369216.1">
        <property type="nucleotide sequence ID" value="XM_060504140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0D5"/>
    <dbReference type="GeneID" id="85388039"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="518"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="21"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="178"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1729161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="729" mass="83073" checksum="1E4CE4FD03F54586" modified="2024-05-29" version="1">MATLRDLYSDEKTKGLDTNFGVDYVINYKIPQEDRASAEASFVQLIEALTHVGLTTEVRRGDKSSVLVFIKIADKFLADQVYRSRLQDWLQGARTNTADKDLSQALRDEPVSDAERLRLVYLLMVKPKNEGGAGITPESGKWKHVASIFPLHNHSFNRQWIKRVSTKGQTDENDLDEIRDKFGESVAFYFAFMQTYFKFLVVPAAAGFGAWMFLGQFSWLYALVSCLWSVIFFEFWKQREVDLAVQWGVRGVSNIQHPRPQFEFERQAEDPVTGEPVKIYSPIKRLQTQLLQIPFAAACIVVLGTLIVTCNSLEIFINEVYNGPFQSYLAFLPTVILVVMTPTFSTVLTKFATRLTEMENYETIDAHHAALVQKEFVLNFLTSYMALFFTTFVYLPFGDHLTPYLDFWRTTAQKITPKDVNFQTQEFSINPERISKQMFYFTVTAQVVNFATEVIVPYVKRQVFQEVREVQSKMSKEDSAAKIKDQPEEAAFLERVRNEAELETYDVTGDYREMVIQFGYLSLFSVAWPLTACCFLVNNWVEMRSDAVKIAISSRRPIPWRADSIGPWLNALGFLSWLGSITSASIVFLCRSAGKGDGPRGTPGSIQAWGLLLSILLSEHFYFGAQFVVRLVMKKLDSPGLQREKKERFMMKKRLLEENLGQGVSDQAATPGIEKTEMITMQALEDEARRISTQGHGGAEEAFWLRQRGMAETIQIGRNLISQVSRCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D233</accession>
    <name>A0AAD9D233_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c oxidase assembly protein CtaG/Cox11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_715556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370519.1">
        <property type="nucleotide sequence ID" value="XM_060511754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D233"/>
    <dbReference type="GeneID" id="85395652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="274" mass="30401" checksum="4F253985392D892B" modified="2024-05-29" version="1">MNALPRLPWRIPSQSTRKWSCFFCQHAVRPAPRSLRTPPAGRRAASTTPSPKQQQNGPSFGGAPSMEQIHAHYKRKNATTAYYTLSVILGTVALSYGSVPLYKMICQTTGWGGQPVRAHGPDVDYSEDGLAARLVPVTTAPRIRVTFNSSVSDILPWKFTPQQREVRVLPGETALAFYTATNNSDQDIIGVATYSVTPGQVAPYFSKIQCFCFEEQRLNAGETVDMPVFFYLDPDIVNDVNMRGIETVTLNYTFFKAKYDDNGKFKAPTPFASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2D1</accession>
    <name>A0AAD9D2D1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hsp70-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_601827</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370685.1">
        <property type="nucleotide sequence ID" value="XM_060507124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2D1"/>
    <dbReference type="GeneID" id="85391023"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000028">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000021">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="613"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="615"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="651" mass="70998" checksum="C30B242A6609A7E4" modified="2024-05-29" version="1">MASGGKAVGIDLGTTYSCVAYYSNDKIEIIANDQGNRTTPSFVGFTDTERLIGDAAKNQVAMNPHNTVFDAKRLIGRKFQDSEVQADMKHFPFKVIEKGGKPNIEVEFKGETKTFTPEEISAMVLTKMRETAESFLGGQVNNAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDKKAEGERNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRLVNHFVNEFKRKHKKDLSSNARALRRLRTACERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCQDLFRSTIQPVDRVLTDAKVDKSQVHEIVLVGGSTRIPRVQKLISDYFNGKEPNKSINPDEAVAYGAAVQAAILSGDTSSKSTNEILLLDVAPLSLGIETAGGMMTKLIPRNTTIPTKKSEVFSTFSDNQPGVLIQVYEGERQRTKDNNLLGKFELTGIPPAPRGVPQIEVTFDLDANGIMNVSAVEKGTGKSNKIVITNDKGRLSKEDIERMLAEAEKFKDEDEAEAQRVSAKNGLESYAYSLRNTLSDSKVDEKLEADDKEKLKTEIDTIVTWLDENQQATREEYEERQKELEGIANPIMMKFYGSAGGPPGAGGAPGGFPGAPGGAPPGNHDDGPTVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4V9</accession>
    <name>A0AAD8U4V9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_644619</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000266">
        <property type="protein sequence ID" value="KAK1704315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357422.1">
        <property type="nucleotide sequence ID" value="XM_060509764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4V9"/>
    <dbReference type="GeneID" id="85393663"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF193">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G00940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="85"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1704315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="583" mass="62142" checksum="F0FD13895991CA56" modified="2024-05-29" version="1">MDQSTSRSSRELTETRFTSPASAMTQPSTTSAVLNMSEKPLQPASDSDVEQTEKKEAGTEDEGSTAADQEEAEEEYIEGLKLILVLAALTLTVFLMMLDMSIITTAVPEITTAFNSLSDVGWYGAAYSLCGAALQPLAGKLYTHRHSKEIFLAFLFVFEAGSLICALSNSSTLFIIGRAVSGMGSGGLFNGSLTIIGATVPLEKRPLIIGIMIGISNIGIVAGPLVGGALTQYTTWRWCFYINLPIGAVTAAMLFLIHIPSKITKPVSFLQIPRHLDLPGFTLFAPAAIMFLLALQFGGNDYSWDSSVVIGLFVGAAVTAGLFIFWEHREGDDKAMVPMGLFKNRIVLTSSLVGALNMSITQVSSYYIPMYFQSVKGETPFRGGVHFLPTIIAQLVFAVASGALVGRLGYYLPWAVFGSVLSAIGNGLISTWDPSTDSAKWIGYQVLLGAGRGACMQMHIIAVQANIPPATLSVSMAMLVFLQTFGGAVFLTAGEVIFSEGLGKNLAKYAPTVDVKTVLAAGGTGFRTVVPEVDLPGVLVAYSKSIGEVFYLMVGIGGLAFVLSWGMGWVDIRKKKGEKKGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U928</accession>
    <name>A0AAD8U928_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_591874</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000180">
        <property type="protein sequence ID" value="KAK1709711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358622.1">
        <property type="nucleotide sequence ID" value="XM_060506485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U928"/>
    <dbReference type="GeneID" id="85390384"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="47"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1709711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="30921" checksum="9B4353571C687B2D" modified="2024-05-29" version="1">MPRKIRREGSCTSGISYDAMHPLLVAWRQSRGEQPLVMSGRTIEAFSMPVLFEPGTSWVYGASSDWAGVLVERLSNMKLATYMEEHLFRPLGLTNTTLDITERPDMRRLLAQMFLRTEEGKLAPIPSPYPEDAQESSGGMGLITTTSDFVKVLTDLLRDSPVLLKAESVTEMFTPQFHQGTSQYGGLIKQEALHKQLTGDDTGCPGVAFGLGGMVIKEGTPNLPAKCLTWNGMPNIGWFVNRESGLGAVYVSQLLPAGDSKSAKLLGEFWQQVWVDHLAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Y7</accession>
    <name>A0AAD8U9Y7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="4">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_636050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360181.1">
        <property type="nucleotide sequence ID" value="XM_060509225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Y7"/>
    <dbReference type="GeneID" id="85393124"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000389">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="45"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1715038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="26180" checksum="71CECABAC4E8C40C" modified="2024-05-29" version="1">MLNGEDPPERPDYIVNIINGLERYNPEAVVNLESYLQEQCEQKYCDCNANRTLLKLYQLNPDRLKDEVVTNILVKAMTQFPSPQFTLALHLINPSTIAQGELHEAVAKLRTLNSQLEGSQYARFWNTIDGDDLCADLIADISGFEDLIRSNIANSVAQAFREVSLSQLESWLGLDGDATAKFVTEVAGWTVGDNGVVTIPKNAENEAKKSEIREDVNVDMFSRILRRSWEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAX6</accession>
    <name>A0AAD8UAX6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_641803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358454.1">
        <property type="nucleotide sequence ID" value="XM_060509575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAX6"/>
    <dbReference type="GeneID" id="85393474"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF25">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1708936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="626" mass="70287" checksum="65E1481915C301F7" modified="2024-05-29" version="1">MKPRRCCDACRRRHRKCVVQPGATGCGACIEADLECHFDTTLRFKHAPGSSRKAALSGDRVQKADHRARRKSEVSRVDDAASEASSSPAVQSVRTAGDRSNSFTSHPSPHGLTPYEGQLNFDYSPPATHAFRAEAPAQRFTGHGSHGDGSAPIGFVLNSGPPQENRQHRDSFTSSPGYLDSSRDGITSDSGQWQSGEVQPQLQISYLLGDSPSTQAGSSHQIASERAESLISDAEFRIQPVDPEHCGFTGRQAFLFRTYILRIAPSIDACHDARPFTLDVPRLALRKPILLNGIFALASRFDTQGNDDINEKSDLESTYYHNRCIELLIEAFSQPPETWDSILLTAVVIMRLYEEYDNETDSHYHHLRGTRNLLNHDAIARFVTQGGLAEAASWVHLRQALYVFLVRRTPIEICLENFERSSTFRSNDDTAHANRIVYLFAKVLKLFFPEDGSGFSTSSSETWEELQNDVDAWFKEKPLSFQPLFYERADVAKGRPFPTLWMAADPGTVALGYYYASKAIFSFQDYNSSNPTAGFEGTKKRMDSEREITFYLCMLMGLARSNEAVNAYYLPAHMLSLCGHLIRHSLEREHTIKYLAQVRTIVQWKTGALVKTLKEQWSQLDSFQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBH9</accession>
    <name>A0AAD8UBH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_592362</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358429.1">
        <property type="nucleotide sequence ID" value="XM_060506527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBH9"/>
    <dbReference type="GeneID" id="85390426"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF14">
        <property type="entry name" value="GABA PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1708911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="523" mass="56586" checksum="67D1BB51CC681125" modified="2024-05-29" version="1">MDQNETKTDDQLKAVDSIPGYLVLSDEERLAQLGHQQELKRQFSLTTLGALCLCLMATWEALSTVIAQALLNGGAPCLFYNFVLSFLCSVCIASSLGEIASIYPTAGGQYHWVAALCPPRSRSLAAFTTGWISVGGLIVFCASAAFAAGLQTQSLIVINDDSYIPARWQGMLFYWAVLLYSAALNIWGSKMLPHANMISGILHVVGFVVILVVLGVMAPKNTASFVFTEVVNSSGWENDGVSWLVGLISAVYPFLGYDAACHMAEEIPNAPRNVPIAMVGSVTVNGLMGFIYCTVLLFSTGSLESLLTTPTGFPFMQIYLDVTRSRAGATVLSLLVILIAIAATVGGITSASRTLWAFARDRAVPFDSHFSYVNKKLQVPVTSIVFVTMAQILLGFLYLANTTAFNAVLSMAIIGIYLSYSIPIAYMLFVGRGKLTRKEYGPFRLGPVVGPVLNAISLVWMTVVIIFSTFPSSQPVTAQNMNYSTVVMAGWLVFGLAYYFIRGRAKFEVPVVVSDIVEGVRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC69</accession>
    <name>A0AAD8UC69_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_632622</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361321.1">
        <property type="nucleotide sequence ID" value="XM_060508983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC69"/>
    <dbReference type="GeneID" id="85392882"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="28980" checksum="A5FE012B8308AC81" modified="2024-05-29" version="1">MSEFLDAYWQAPPVARTFATAAFVTSLSVLLGVANGYWFIFMPQFLFQIPPQIWRLGTNFLLTGPQLGLLFDTYFLYHYLTALEVGNPRFARREDVIWYLMFVCTVITALCTYLMGGGAFLPALILAMCRTVTQDQRGMKANFYFVTIPAQLTPFCMMLVSLLFPGGYYTAMLQLMGFLAAHLYDFLSRVWPEFSGGSNLIPTPGFLSRLVQTPRFNQRGYGTAVRGGGGSAQSSGSSTGVSQGGGVLPESWRTRGPGRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCF3</accession>
    <name>A0AAD8UCF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Soluble quino protein glucose/sorbosone dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_590977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000162">
        <property type="protein sequence ID" value="KAK1711213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359016.1">
        <property type="nucleotide sequence ID" value="XM_060506386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCF3"/>
    <dbReference type="GeneID" id="85390285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121913" evidence="3">
        <location>
            <begin position="21"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="4">
        <location>
            <begin position="36"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1711213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="51202" checksum="5C41630F30358A54" modified="2024-05-29" version="1">MNLLLSLHILASSQLSVALAQECRNTLKTTYTSPIAAGGWTYRLIANGFTRPRSILFDNQGALLVVDANSGVKHLKLTDDGGTCLSVAEKRTIIDSPELNHGIALSPDGKTLYASTADKVYSWSYDGSAATVGDRNRTLIANMSNTDHTTRTLLLSNKSPGILLVSRGSASNIDEAATRQSTGHSQLRAFDIGSLGENSGPLNFPTEGKMLGWGLRNSVGVAEEPVTGGIWTVENSADQLRRNNVDIHTDNPAEELNFHGYLSNSNKDQGGNYGYPSCFAVWSTEGFPDKGNMTTGDQFTLSPSRTLNDTTCNSAYVPPRLSFQAHTAPLDIKFTSDGSEAFVTFHGSWNRDVAVGYKLSSIRFSNGEPTESADSRTPTTDVLSNADTSSCPDNCFRPVGLAWDSQQRLFMTSDSTGEIFVLQRTDVSVSTSSPAAPVPTSSPDAAATLVPSWLTSFGSLAISVFVFMGGAGVVRLIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH0</accession>
    <name>A0AAD8UCH0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-deoxy-D-gluconate 3-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_592756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358250.1">
        <property type="nucleotide sequence ID" value="XM_060506562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH0"/>
    <dbReference type="GeneID" id="85390461"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000398">
        <property type="entry name" value="Probable 2-deoxy-D-gluconate 3-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF5">
        <property type="entry name" value="2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1708218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="263" mass="27893" checksum="A279E8B150E5E561" modified="2024-05-29" version="1">MPTILEKLFSLEGRTAVVTGGTRGIGQAMAVSLAEAGSDIILIQRDESNTETKIQVEALGRKAIIYTADLSNQEEVESLSGRILADGHDVSILVTCAGIQRRHPAHKFPMGDWDEVLQVNLKTVWTLCRDFGAYMLTRTPNLVNGHRGSIVNVASLVSFQGGITVPAYAAAKGGIAQLTKALSNEWASQGVNVNAIAPGYVATDMNEALINNPERAASILARIPAGRWGTPDDFKGATVFLAGAGSLYVSGELLTVDGGWMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD08</accession>
    <name>A0AAD8UD08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sas10/Utp3/C1D family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_641448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000184">
        <property type="protein sequence ID" value="KAK1709386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358520.1">
        <property type="nucleotide sequence ID" value="XM_060509560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD08"/>
    <dbReference type="GeneID" id="85393459"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF9">
        <property type="entry name" value="NEUROGUIDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="364" mass="40031" checksum="870AD36C6079506D" modified="2024-05-29" version="1">MAAPSTLPALLDSLTHSLTTSLDAAPKGSIAPPQNGISLLDTKNELLASYLQNLVFLILLKLRNAKKQSSDDDSADETMETVVRKLVELRLYLEKGVRPLEDKLRYQIEKILRAADDAERNAQAVKAAQGAGSEDSDDSASDGETGSDEEEEEEMKAAHLQARPDAFVRPAAASAAVATAAKNGVYRPPRIAPTIMPSERKEKSDRRPLKSHTMDEFIEHELSTAPIAEPSIGTTIVNGGRRMKTAADRKTEDERREYEEANFTRLPTSSKKAKKEEAMRTGNGKRMQFGGEEWRDLGEGVDRINRLTARKSGGGSSRDILDKSRKRGRDTADGPRGSGQAEMGERFQKKAKMLEAGRRDRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD81</accession>
    <name>A0AAD8UD81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_90714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359639.1">
        <property type="nucleotide sequence ID" value="XM_060515997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD81"/>
    <dbReference type="GeneID" id="85399895"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="718"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="750"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="789"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="887" mass="99360" checksum="34ECC45620905860" modified="2024-05-29" version="1">MTFSKDFQLAKHLMPCAMEAFIYESRTEASVNKSCEKSDPFEGFLDLLLDGVIYATIALVLGIGLVVMIGKIRWVNFPRRRHVTVIETPVDPRTFNSSDVGKGQGEIMTNPIRSAKEASLRETPSLGTSAIKPSSTPVRFNATEPLLTEPSHVRSLSGNSPPAVAPRMPSTTTALTSTPTPTPREPQRPLKVILTPKFPENISTEAEINPNAVFESEDKNILKEFVRILHDYKEDLFDNHHFDLPHIVPILVSVSSTQTSSQIKTLASKLELVGKTPTRIRIDGLDDWGQMRRFHKIMSKNKHIFTPLHLCYHKKEVLPAALGITCVIRDPALDRTLCGSLVIVQTPSLGQRTSTIGGLLSIRGSFYALTTSHMPHNDDEPSEDSADDEGNSEARSVVIYNVDTDSEDSDSLTPSGSDDGASEECENMRQLQETVLLDDSTSNVIPRNTEEVEIMASGDVDASITTEAEPHSDEIGAAVSGQITPEDLAEKEGYLTSQFQEDDLRSGDDWLLVPVENDLLLPNRIPEGMEKPIQWQNPFIEGVCSDLDKEFGHRDMSPSAQAVWTISGRSGLLRGRLCPDSTFMISRGGKKVQEVWIVELDDPSQDFQAGDSGSWVVDTRLRRVLGILVARSSGVGYIVSFAKVRQNIASTLRIKEKSVKLASRMDPLIRGRGGGEVLRSLSPIRTRSRQEPIPLFWRLWGLILPDSVIDVVRYPEDLGIHISVIVVFGAIIYMFLMWQFQSAWYRMTMAQHALLPSWFALFLWVLAEVDMLGRPRDFNPDRRLAARRLYYSWLRVVFWSGVLGALGIYSARRQRISPFTLLFNITRWMDKFQQKWGEMRRAAQEAERKDRDPVAEGLRNLGMAWNNYVGNSNGTGGRFSMRKWLMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDD4</accession>
    <name>A0AAD8UDD4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_722619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360823.1">
        <property type="nucleotide sequence ID" value="XM_060512486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDD4"/>
    <dbReference type="GeneID" id="85396384"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042225351" evidence="1">
        <location>
            <begin position="18"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="16094" checksum="6B39CAC3A3ABD0A5" modified="2024-05-29" version="1">MRVSSLLALVSAALVAAAPSPVPEDANSYVLAGPLPYEELKTEVAKLKSDGSNAARSLNKRICEGVYMCDGQNFSGSCYYGCYPISVGIYPDSYWVSRISSVGPDSGGWCDFYQAGSGCDATKGSHQIFRYPGGNLAGGIDNNMGCFYCNPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEB7</accession>
    <name>A0AAD8UEB7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_756680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359824.1">
        <property type="nucleotide sequence ID" value="XM_060514782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEB7"/>
    <dbReference type="GeneID" id="85398680"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000388">
        <property type="entry name" value="SsDNA binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302:SF0">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="145" mass="15653" checksum="B67315CCFA20BC08" modified="2024-05-29" version="1">MSASALFRRAAVAPRMASAARAFSTTPSNNVARITIVGNLADAPEVVPTSTGREIIRYAVASNSGPKDNRQTSWFRVTSFEAEGPRRDFLQSLPKGTLVYVEGEAAMRAYQDAEGKNRSSLSIIQRSIEVLKRPYSGNNGGEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF10</accession>
    <name>A0AAD8UF10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_721893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361828.1">
        <property type="nucleotide sequence ID" value="XM_060512417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF10"/>
    <dbReference type="GeneID" id="85396315"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF27">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1720317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="30672" checksum="9D17918EDB87B35B" modified="2024-05-29" version="1">MGSSNRVKPTKGGAYLWRYLPNKPAAILFLILFLLSFLYISWKIWRTRARFCIVFAQVEVIGYGARASAHDKTDRIMTFAIQNMFIIIAPVLFAASIYMILGRIITSIHAEKYSMIRPAKLTKTFVLGDLVSFLIQGGASGMMVIQKPGLATWGERIVIIGLVVQIIMFGLFCAIAVVFHRRMRQAPTPDSLDGLIPWEQSLYMLYAVSLLIMVRSIFRVVEFAQGYTGYSLSHEWTLYVFDSLLMYLVTVLFAWRFPDRLRSKEDLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFW1</accession>
    <name>A0AAD8UFW1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_702050</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPI-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="13">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363537.1">
        <property type="nucleotide sequence ID" value="XM_060511449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFW1"/>
    <dbReference type="GeneID" id="85395347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="5 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="195"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="318"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="594"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="810"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="830"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1723482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="859" mass="95666" checksum="4EB10E919920EA5C" modified="2024-05-29" version="1">MKVDVKRQLFARSERVKGIDFHPQEPWILTTLYSGHVYIWSYETQQIVKTFELTDVPVRAGRFVARKNWIVCGSDDFQIRVYNYNTSEKITSFEAHPDYIRAIAIHPTQPFVLTASDDMTIKLWDWEKGWKCVQVFEGHGHYVMGLAINPKDTNTFASASLDRTVKIWSLGSATPNFTLEAHEAKGVNHVDYYPHSDKPYLLTTSDDRTVKVWDYTTKSLIATLEGHTNNVSFACYHPELPVIISGSEDGTIRIWHANTYRFEQSLNYGLERAWCVSYQKGKQGVAVGFDDGAVVVKLGREEPAVSMDASGKLIWARHNEVVSAIIKGGDASIKDNEPISLPVKELGTCEVYPSTLVHNPNGRFVAVCGDGEYIIYTALAWRNKAFGSALDFVWASKENTNDFAIRESATSVKVYKNFVEKAGGLDVGFQAEGLTGGVLLGVKGQGGISFFDWQTGGLVRRIEVEPREVYWSDSGELVALACEDTFYVLRFSREAYVEGVQTNQIDEDGVEAAFEVITDINESVRTGEWVGDCFLYTNSTNRLNYLVGDQTYTVSHFDQSMYILGYIQRDSRIYLADKDVGVTSFSLSLPVLEYQTLVLRDDMETAQELLHTIPADQLNKIARFLEGQGHKELALEVATDPEHKFDLALGLGQVDTVLELAREADVEHKWKTVGDAALAGWQVAVAQECFTHAKDLGSLLLLYSSTSDRSGLSKLSDQAQEAGAHNVAFSCKWLLGDVAGCVEILTKTGRLAEAVLFSQTYKPSLTADVVKEWKESLEKGKKGRVAKMVGAPVEDEDLFPEWDEWLQLEKQGGAAPQVAEVTKVNGTDATEAEEAEEAEEAEEAEEADEEMAEAEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGA9</accession>
    <name>A0AAD8UGA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nicotinamide N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_580175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363792.1">
        <property type="nucleotide sequence ID" value="XM_060505321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGA9"/>
    <dbReference type="GeneID" id="85389220"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF104">
        <property type="entry name" value="N-METHYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="301" mass="33326" checksum="42BA2E54AF786DD6" modified="2024-05-29" version="1">MALTSRISLTGPPAESPEDYLMSSLGVIFPDDVTNQHGDAVNGIEYTSPHLRRPLTFELAEPDAADDRKLFSHYLWNSSLQLGEFVEAGTLGIDTAVPIRLGPPLSHFDVRGKSTLELGAGTALPSIMSALLGAERTVLTDYPAPAVMKSLRLNATRNIVPAVSPTGALTAREVLVEGHSWGELDDAFSLANKHAFDRLFVADCLWMPWQHANLQKSIAWFLREGTEARCWVVAGFHTGRPKMRGFFEEASLADAGLEVETIWERDCDGEEREWAWDRGIEDVTIRKRWLTIAVLKRKDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHH8</accession>
    <name>A0AAD8UHH8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_652592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364081.1">
        <property type="nucleotide sequence ID" value="XM_060510539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHH8"/>
    <dbReference type="GeneID" id="85394438"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="44"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="529" mass="59087" checksum="197BDFD9D361A5FD" modified="2024-05-29" version="1">MGFLKGVTQKKTNSEAVVIAQEEAPDFEKVNWVKDPGLRKLYFYAFVLCIASATTGYDGMFFNSVQNFDSWQSFFDHPKGGQLGLLGAFYQIGSLVSIPIVPFIADNFGRKIPIVIGCLIMVAGAVLQGACTSMGMFMGGRVLLGFGNSFAQITSPMLLAELCHPQHRARLTTVYNCLWNVGALVVAWLSFGTDFLGNEWSWRIPAIGQAVPSVIQLAFIFWVPESPRYLIAKDRHDEALAILGKYHANGDTNNPTVQFEFREIRETIKREIAAKNSSSYLDFFRTAGNKYRFIVLISLGLFSQWSGNAIISNYTNILYANAGIESSTARLGLSAGQTGLSLVTSLTLAMQVDRFGRRPIFLASTGGMLMTFVFWTLSAGLYEEHGSPGSNYAMIFFIWLFGFFYAFAWSGLLISYSIEILPYKLRAKGLMIVNLTVQAALTLNNYANPYAFDYFTGHTWKLYLIYTCWIFLELVFVYLFYVETKGPTLEELVKVIDGPDAQVADLDLAQVEQEIKLGHEAEELEHKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW9</accession>
    <name>A0AAD8UHW9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear distribution protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_356763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364291.1">
        <property type="nucleotide sequence ID" value="XM_060502553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW9"/>
    <dbReference type="GeneID" id="85386452"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="22261" checksum="B913753DDF0B758E" modified="2024-05-29" version="1">MDNSLDKTTLSTISLLESRLLRIEHLLYGPTAPSHSSQADSAVDTLEDLERRFNHLLSRIRVYGELMKIYNSQPTLFQPPSPSEPPIHLAPEAIRATVLASAAAFPATASSLTSVNDCPIPESSQSAALASLMPRLHGIEATQIAQEAEMAELRARSEEVLQAWYQQGVLGVSDFVADVEGRVEMVERRVRRAEREKEAAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIB8</accession>
    <name>A0AAD8UIB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364857.1">
        <property type="nucleotide sequence ID" value="XM_060508301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIB8"/>
    <dbReference type="GeneID" id="85392200"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="284" mass="32058" checksum="2935F8F2C2CA8D21" modified="2024-05-29" version="1">MAESITATMAASRKRSRPGSDTTNTTNTTTCKTTLASINFNDRPPHPTTIISLPKNEDEVETLLEKTSALADVVSHNRSLAVYTAFAATPNPKRDPVAIAKREADVRELEMYDRFEQIGCQPQLWMKLDVLKDVKPLDRENKKTAARYEDMASCVDEVCGTTGATKENVAWIVENREVVLPLVKFYLRIKRARRNLSGGQACLSSNELAEYQTVRKIRSVLGVRMQKFRMEKASERRLRGYDVVLLRRQNEMNAILKGQRDRDGKSDDGFVADGGETRAKRQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIR0</accession>
    <name>A0AAD8UIR0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_583397</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362328.1">
        <property type="nucleotide sequence ID" value="XM_060505654.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="393"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="882"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1207"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1424"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1722273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2130" mass="232952" checksum="DFCF57B812E974BF" modified="2024-05-29" version="1">MATIFQSFRSSTLSKRLLIYALRRLELLDEETLDMENLQFALGRTTTAEFKDVGVRLKKLERLLQLPASFQVQKAKVLKLNVTIPVDFYTSPIVIEIDGVDVRLKVSTIGDDKKTKAAARSDDAQGLPDTVNLAQSFLNEDAALKDAKLAEEKRRLEDALAAETQDLGGSTMSESSMSDDGSQFGTGQPLSLPGFLAGFLQGIVDRIQVRIRGVTFQMDVEVPLEPTSTTPELVTFQLALDRIDVEGVTAEAHNDEGAPTIVPKDGKRHIALSKIRAYLISEATVFSQFARSPSVSSPSISQSPSFSERTSASRHSTFRPTMQESFLSDSADLSEVDDALLQDSEEAFNIPYDFSSQPEEQAEEEEPTTPRASIYQDFSPQRHIPLSQSTIQGDTIQGDEDEPVPWASFQREARSEPSLQSADNDMLNDVGDFAPTEALQQSVTASQSSSSGEVDDLAQSHVFTHEEAESMYMSAFSQAEPTGSRMPGGWDADSSPEASPKLKKSSPVPRQQTPPAFEAAPSIPESKPLDNMDAPASQRSQSPPPVDQPDPRFEDAKEPPSASFTRDEFADAPAPADDVATPRGPTRLVKELVSLQNISLYVPSLHHHVHVPADAQASVLSQAPGSPGLARSVAPQLPGAFSVYSPPSASRPGFAPMPNDLPFAEPDNNGALEVLLSPLEIRFDASLAYLLAVVAGKLLDALKSKDSLAPAPKTAAKPQQESTMPDINVVFEKISLHFLHQLGGVADTAERILGSPGLQMQPEILLRTDLDKLNISLKSSKKGLETTVDLEKFRFGYARDDIISFDQSLQMRASVMDKFPSAGSDVTVKVVKSADSIRTEVTTLPLLIQLDLQRLDETFSWFGGLSSFLNMSSSMSSNASPSVRAPVLPPPKPRGVRFDAPINPDDKSASAENKIDMRIGGFNLELKGRECSVGLETSAVKMVSRDLGIGFAISKVRLAGPYIRNSRAEPPISAEIGGVRFEYLATPKDKDLERLLELIIPSKAKFDQGDDEIMVDTLLRQRRKGGVLRVTFDQLNVRVDRIHQLNCLPALGEEVARLATVAKYLPEDDRPGILLLAEVKELGAVIDLGGKLGTINANLKNFEVAQITVPSLVAFGVHAISVNRNHREELVSSSTTLPPGTLTQGPVLMVRMIGDEMEPVIKIKMRDITVDYRVPTIMDVLGLGEDATPQDFEASLAASVANLGEQAHSALTGKKPQPARMTEPTRPNSKPMTVDLVLRDCLIGLNPLGLPSKLLIALTDARLQVVLPKDVDTTANLDLNKASILLIDDITNIGANSTVNRRQSADMSSQQVSRLVSQGYVSICYISSAKAGVKVSESRDDGEKHIDVELRDDLLVLETCADSTQTLITLANALTPPTPPSKENKYRTSVVPVQDLLASISAEAFGRAEGDYDFDKDFELAQELGGSDEDDMSGDGSPLQIDSRYYEDAGPSEPLFDAEGSITSNATTTQDTHDGVLLTSFNASASHHSDDGSDLVIHENFFDKGPETDGRAQVWNSSKNSYDQAPKELVKRSPLRVSVRDVHVIWNLFDGYDWERTRDVISKAVRDVEDKAYERRRRSERAVFEDDAEEDETVIGDFLFNSIYIGISTKQDPRELAQMVNQELNDNATETESLATTAFTTTTGRTGAVRPKKRLRLNRSKHHKITFELQGVNVDLIAFPPDSGETQSSIDVRIQTLDVFDHVPTSTWKKFATYDQDAGEREMGTSMAHLELLTVKPQPDLAASEMVLRVTLLPLRLHVDQDALDFITRFFEFKDDSAPVHSSTSDVPFLQRVEVHDIPVKLDFKPKRVDYAGLKSGRTTEFMNFIILDEARLTLRHTIIYGVSGFDRMGKILNDIWMPDVKGTQLAGVLAGLAPVRGIVNIGSGFKELIEVPIKEYKKDGRIVRSIGKGAAAFARTTGTEMVKFGAKLAIGTQYALQGAEGLLNKPQTDNTWEEADLDPEEKKQISLYADQPTGVIQGLRGGYSSLTRDLNMARDAIIAVPGEVMDSSSAQGLAKAVLKRAPTIIFRPAIGATKAIGQTLMGATNSLDPQNRRRAEEVSFLKPGCIFVKISLLTMRLEIQEALKIPVGSSFFTRNAHALHTPDTRNKAFGTFFYFQLPFFYCLLNSFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ07</accession>
    <name>A0AAD8UJ07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ketopantoate reductase PanE/ApbA-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_620189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365292.1">
        <property type="nucleotide sequence ID" value="XM_060508179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ07"/>
    <dbReference type="GeneID" id="85392078"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000609">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="15"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="214"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="38396" checksum="9996B3F3D5D2E669" modified="2024-05-29" version="1">MGSEKNNSSESAVNIIFIGAGAVGCFYASRLHHPDRNIHVSLVARSNYKALKESGVKLQTHTFGDYVFHPYAAFPSVDAAASSQTQWDFVFVTTKALPDRSDDSAMIAPLVGKNTSIVLIQNGVGVEEPFRQRFPNNPIVSAVTIVSAEQTSPGVIRQNRWTRVSIGPHTNGLGTGDAELGQRGTKAIEQLGTWWGPGWGGIRDVEPHDEIGLQTVRWHKLCINAAFNPSAVLSGGRGNADMVTDPELREHVVGIMNEIRAAVPKILGREFPDDLAKPDRIVKSTERNTGARPSMLLDWEAGRPLELEVILGNPVRIARAHGVEMPRLQTLYALLSSAQRTREERATKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ43</accession>
    <name>A0AAD8UJ43_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_777447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365352.1">
        <property type="nucleotide sequence ID" value="XM_060515481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ43"/>
    <dbReference type="GeneID" id="85399379"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="45736" checksum="D0923F59CCE95CD8" modified="2024-05-29" version="1">MAVQGLFPSWHRSKGLDYDAVESDPSSRTERPSLSEVIASKRFRWLLGTVIGVLLVVFVLDNSVQISRFRRPTSPSSHELSQVKGATGHADVDWSRFAYVQYATNTPYLCNSVMVFERLQHLQSKADRILLYPSEMLDPLATSGNTKDASLLIHARDTFGVKLIPITVQHRKGSDPTWAESFTKLLAFNQTQYDRVLSIDSDSTLLQNIDELFLSPSATVAVPRAYWLYPEKKIVASHIMLVQPSVAEFARIVEKVDHAGKEEYDMEIINDLYKDSAMILPHRPYALLTRSFSGDHQDYYLGNGDEVWDAVTVYNEAKYLHFSDWPMHKPWLKSSESLIKERQPDCVAKDGNEDCTARELWLSFYTDFRARRSVSTLDSIQLLRRFHLTSFVQEDYRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ79</accession>
    <name>A0AAD8UJ79_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_628321</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362790.1">
        <property type="nucleotide sequence ID" value="XM_060508695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ79"/>
    <dbReference type="GeneID" id="85392594"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF1">
        <property type="entry name" value="ALLANTOATE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="85"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="59215" checksum="94745C3D33AF3C9F" modified="2024-05-29" version="1">MADHDIKGVAEPPATDDVSNSDERSASVASNLAPTGAKNPEQATKSLPKTGADAALELLNETGPLGRTVDPELNRRLKRRIDTHIMPLICIVYFLQYIDKTAISYASVTGIQQSTGLHGNQFNWVASIFFFGQLAFEFPTIRLIQMFPLAKYTSINIILWGVVLACLAACKNYAGLLVCRFLLGAFEAAVVPAWVLFTSQWYTKQEQAFRVGIWFSVCGAAQMFGGFFAYGVATHVGKDPNAVLRGWQVIFLFLGLLTAFIGIAFFFIMPDSPATARFLSQEEKATHLERIRDNEQGIGSQEFKWKHVKEALLDVMTWLYAFWIFAANIPNSIATSFGNILVRGMGYTSEESLLLVTPLGAYEIVALIGLTWLAMKTRQRLYWCIAGHIPAIIGAILMATTSKVPALIGYYTSGGIPIGWTTILGLQSTNVAGSTKKVTVACIGTIAYTIGNIISPQTFQARDAPRYLPAKISICIIYFLVTVDLFLMRWVLERRNKKRDAEKTALGDAYKVEENHEFWDLTDLENKEFRYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK16</accession>
    <name>A0AAD8UK16_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_619925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365401.1">
        <property type="nucleotide sequence ID" value="XM_060508159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK16"/>
    <dbReference type="GeneID" id="85392058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000670">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000672">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF81">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="79"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="61576" checksum="6DB5EDC5C10F7C96" modified="2024-05-29" version="1">MSNPHSRPRLSDDEVGRARANLPNPASPPPPYYSDPDTESAAAAAAIAAPREDQPLLRDPAAAVEAGESWKPPRGFLWIELAIMANVFLYGFDGTITAATYAVISSEFDAANTASWLTTSYLVTSTAFQPLYGRFSDIFGRRVCFFVSSITFGLGCLGCGLAGDVVLLNCMRALTGFGGGGLMTMATIVNSDMIPFRKRGMYQALQNGMFGFGAVAGASFGGSIADHIGWRWCFLLQVPVSVMALALGALVIKNPEGGFDIDTNDWRAIWSRVDVSGALLLVVAISVQLVGLSLGGNELPWGSPVVIGTLVGSVLLLALFVLVEARTTAIPVIPLRMLRGKLPILTQISNVCAGLAAYAYLFMLPLFFQVVLLDSATKAGARLAIPSLATPLGGLFAGIVMSRWGKLIWLVRAGAFLMLFGNTLVTALQFQDSQWKYLVYIFPANLGQGIIYPAILFTTLASFDHADHAVSASTVYLVRSLGTVWGVAITSAIVQTTLSVRLPEALGDIPDKSRLIDEIRHSVTALKTLPVEVRLPARHVYYEGIQYAFAASTTFAGIALIASLFASPRGLRSTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKA3</accession>
    <name>A0AAD8UKA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_583849</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362120.1">
        <property type="nucleotide sequence ID" value="XM_060505702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKA3"/>
    <dbReference type="GeneID" id="85389601"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1721324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="465" mass="50483" checksum="D6469915A763A929" modified="2024-05-29" version="1">MASVACFVPPMSANIYYPVLAPIADDLHVSVALVNLTVTSYMVLQAISPTLFGDFGDMAGRRPAFLVAFSIYLVACVGLALQRDYAALLVLRMLQSGGSSGAIALGFAMVADISVSSERGKYMGIVGAGINVGPTIGPVLGGVLTQYFGWASIFWFCVVLISLWLIPYALFVPETCRGVVGNGSVPPQPWNRPLIDLIRRHRNRRHQNPGDLSQTESIPAHPHRKLRFPNPIRSVKIIFEKEMALVLAYNSLLYVAFICVAATLGTLFREIYHFNDLELGLCYLPYGAGCVVASLGQGYVLDWNYRRIASQIGFAIDRRRGDDLLKFPIEKARLQPVYPAVAVGLAALTVYGWVLHFEVGGVAAPLVLQGVIGLTITGSFSVMNTLIVDLFPDAPATATAANNLVRCAMGAVGTAVIEYMIRGMGRGWSFTFLAALCAVLSPMMFLIAKKGPVWRNARRMREEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKI7</accession>
    <name>A0AAD8UKI7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_751242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366057.1">
        <property type="nucleotide sequence ID" value="XM_060514028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKI7"/>
    <dbReference type="GeneID" id="85397926"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051170">
        <property type="term" value="P:import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000366">
        <property type="entry name" value="Protein FMP52, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF7">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="24891" checksum="BD4314BC0B93D56A" modified="2024-05-29" version="1">MAHNAAVIGSTGLVGSHILGNLITSEAFAAVNTISRRPPKAGGLTLKPVIEQDTSAWPPKLAALQPTPTVVFSALGTTRAAAGGIANQWKIDHDLNVELVKAAKAAGSKAFIFISSGGTRGALSAQAPYSKMKNGVEDAIKEAGFDHGIILKPGLILGAREESRAGEGVFQSVVRGLGMLNRGVQDTFGQEAEVIARAAVHAAVLVEQGKAPAGLWVIEAPEIVRLGRTEWKHGAWPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKK4</accession>
    <name>A0AAD8UKK4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_617712</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366087.1">
        <property type="nucleotide sequence ID" value="XM_060508038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKK4"/>
    <dbReference type="GeneID" id="85391937"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17964">
        <property type="entry name" value="DEADc_MSS116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="95"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="311"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="537"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="548"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1726032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="581" mass="62468" checksum="63EDB4A470831E5C" modified="2024-05-29" version="1">MDRRGRGSNQKRGPRRDRRDAPYNESPRSGQPASAPVASATAAAQATAPPLTEPVPQDTPRFADMVGVDQSLVQAITQDLKFDHMMPVQAATLGELLPPKRGDCLVQAKTGTGKTIAFLLPAIQTLITSNRGRGAGISLLVISPTRELAMQIAKEAEALLQRLKQYRVCIAIGGTNKDREEKQILNGCDILIATPGRLIDHMSNEYIKDAFRHLDTLVLDEADRLLDMGFMPALKDIVRALPDKTKTNRQGMLFSATIASHVEQVAGLVLSQGYKFISTIPAGEANTHERVPQHLIKVPTFAAVAPAMVGAIREEATHVGPETFKAIIFAPTAALADFYGDVLSNVPGMPPTAVLHSRISQSKRTKTTNDYRDSKSGILVATDVIARGMDFPGVTSVFQVGIPADKESYIHRLGRTARAGAEGRGIFIVAEVEGFFPQWTLKEITFQTRPADLSSAEAVYDIAEQRIDEAQKAKIYQAWLGYYKNWMKPLKWDKEQLVAEGNTYARDALACPETPAIQKSTIGKMGLRGTRGLVVIPDAPKSRHGHRGGGGGGGEGRPAGSGGRGGGGGGGRGGGRRGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKL8</accession>
    <name>A0AAD8UKL8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_560197</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364592.1">
        <property type="nucleotide sequence ID" value="XM_060503554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKL8"/>
    <dbReference type="GeneID" id="85387453"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF149">
        <property type="entry name" value="UBID FAMILY DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="37"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="39766" checksum="A10AFBB1D36F7126" modified="2024-05-29" version="1" fragment="single">MVTGNESFGASLERQSWIHYSIGMAFIFLRMLGGVSNFEADDYLQILAAVLFTVLVALLNIITDGGGSNLYPPELEGTFTQAEIEDRIHGSKIVLVSEQAMLNLIYVLKACVLILYTRLTLNLAAQRLVRWLAMYVALGWTATQVTMFAACRPFSGYWAMPPPDPQCTTYENYAILQGWFNISSDMLMLMIPLPLVFRMKVPWKQKVVLLFVFSLGICVIVAALLTKIFNLSDPYSPTYMLWYIREASVAVYVSNLPLVWPLLREWFPWLRNLKTAGVLPTPSNQATGHRTKQDANMSSGVTVHSTHRGPAPAGVPNSRRHTFEEFGTWLSASDLELQKPARVLRSSASRRHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL56</accession>
    <name>A0AAD8UL56_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endoplasmic reticulum-based factor for assembly of V-ATPase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_626421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363396.1">
        <property type="nucleotide sequence ID" value="XM_060508560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL56"/>
    <dbReference type="GeneID" id="85392459"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="256"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="32569" checksum="B2B31D4597DE6B31" modified="2024-05-29" version="1">MVRLTITPAIAEGQQKLAEVRFGRRIAATPDDAEQETTSEIAIEIPATDKAEEPTLGNYVIGEPITHSQILDLWKSLKTEGIEGFSLEGLLRGARVYVPPPPPKPEPSAEYKALMARLRREEEERTYQRMLKQPSRMEAFSQQFPSAAARAHAFAEVNRPMNEADHGDDEVTLGDVQKQIMVILNFLISIIGVAATIWIAARWWNVTARIFLTLGGAIVVLIAEVAVYSGYVWRIGEAKSKTKEPEEIREVMQSWVLGKESKGDPTEKTSTLLDTKSQDTDEGIRRRLKGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULH1</accession>
    <name>A0AAD8ULH1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prenylated Rab acceptor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_549767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365087.1">
        <property type="nucleotide sequence ID" value="XM_060503478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULH1"/>
    <dbReference type="GeneID" id="85387377"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="43387" checksum="E100EBB08787312C" modified="2024-05-29" version="1" fragment="single">VGKTIKARAEETGSCATGVLGGWDESCRGARGDGIGQFRYTRRYDYQHSDDDEHDSEDDSEDSEESSSEDDEEEEEEIDWDQLSPGERDEALAQRALARIRRAQERGKLEVNLSKEEMAALERRRKRIEKEARKQERKQRREKEQRFAIPLSQFQPTSSRRRSPTLALEDDLPRHPSPGTFANVQDGGAMPPMGYFPPPNASRTRPRSATSASQRPTSRIMGERGSSPFNYAYVQGSPGQRLPSDNMSPASSTSSLPKSRNGVDPFQFQTEGPASAARRNVSGSTDGRRTSVAPPTGRGGRAPRRPPPEESSSEESSEASSEESTSDGIGNGAQIVQPPQRPPSSGPTTRRGRKEAVAVEEAAAREPAREVSRGKKSANPSPSKRKPTGGRRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULU1</accession>
    <name>A0AAD8ULU1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pectate lyase</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_777731</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365252.1">
        <property type="nucleotide sequence ID" value="XM_060515488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULU1"/>
    <dbReference type="GeneID" id="85399386"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000036">
        <property type="entry name" value="Pectate lyase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042084623" description="pectate lyase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="13">
        <location>
            <begin position="51"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="325" mass="33572" checksum="85224D1ECF56782F" modified="2024-05-29" version="1">MKFSAVTFMAALAAASPANIVTARNELALRQAAEACNIGYCTQGGGTTGGAGGSSVTVKTVDELVAAAKKEGPLTIVISGAISGSAKVRVSSDKTIIGEKGSSLTNVGLYVRQVKNVIIRNLKIGGVKASNGDAIGIDESTNVWVDHCDLSGDLSGGKDDLDGLLDISHGADWITVSNVYFHDHWKGSLVGHSDSNGSEDKGKLHVTYANNHWTNINSRTPLVRFGTVHVVNSYYDKLLLTGINSRMGAQVLVQSTAFNSCPAEAIFFADSKETGYAVAEDVDLGGSKNSVPKGTLTSASLPYKIAALGSGKVAGSVPGAAGQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULV7</accession>
    <name>A0AAD8ULV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein 33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_720298</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATG33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363993.1">
        <property type="nucleotide sequence ID" value="XM_060512260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULV7"/>
    <dbReference type="GeneID" id="85396158"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051668">
        <property type="entry name" value="ATG33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37278:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 33-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="24506" checksum="382E7C5A9DBBCDFF" modified="2024-05-29" version="1">MASKGVSLLKFVGTVSLGLLTGLSYSLSTVTVPSILSLPSASDALRAFKNLYPSATARLRLLTGVSATSFLLAFFLSPRAFRHPYLVYASVLTLTSGLAEQITPYVLKSSPESSKESIAARRQAARDREQKRKAARLARQEARMEASYEVLGDTHSDGAGSASGDESSSAAAAEAEEEALNGEEVRGEVDGFRKTQLVQSAVASVGFLLSVIGIWGDGAIQVFKTETVIVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM95</accession>
    <name>A0AAD8UM95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_650798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366028.1">
        <property type="nucleotide sequence ID" value="XM_060510402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM95"/>
    <dbReference type="GeneID" id="85394301"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="167" mass="18553" checksum="BE462E7834345B25" modified="2024-05-29" version="1">MQCKLAKVSDVVVSDLAPHEGFLGFDERVSEYLDRVHEASDARLRAEWLLVNGKGMRCKFVANPTCRYRWSIFEIYTAATMRGVELPVQEPNVEPSENPNCLPMSELTVYLYPYGLAGLAIPITVSTPKYCPQTKRGVSSIQQKTWDRAVSGVARVSEAGVALVVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMF2</accession>
    <name>A0AAD8UMF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366556.1">
        <property type="nucleotide sequence ID" value="XM_060504716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMF2"/>
    <dbReference type="GeneID" id="85388615"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="407" mass="45997" checksum="E5F65A4EFB2BA43A" modified="2024-05-29" version="1">MWRVFRPRAGISNASTLAVRAVAPQVPSQQTVIVQRVKLSKPRFRAGTFLIGAGISLACWHIYWSTVLNPFFRHVDREYEKLSPAEKKALDEEIAEEDAEPWFIPFPFTTKSVNQPPYKGSDPEWQEFVKLSKQKGTQTQIRADLANWVKSSVERHPVITARCGNSVRLRRYWLDIDFPYRPPPVFYSSGLLLQGDGLYWSTQPVDSLTVKRLQKILWPDAIAVSSWAFTSALLKQHYMDISRALGFESSKPVQPFPSVSGGSMQQKTQGPLPSANRQTPDGTPAENASHNVSKTTDSSQADEPESGGKTNFVRDTAISHIEGMKQITDGPAREFRRKLAQSWKPTRPSPPRGCILVSGFVECELPKGFVLIDVWGFWNPKTETFETKSTFMNVRRVQMKQQSPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UML8</accession>
    <name>A0AAD8UML8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Casein kinase substrate phosphoprotein PP28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_719688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364800.1">
        <property type="nucleotide sequence ID" value="XM_060512203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UML8"/>
    <dbReference type="GeneID" id="85396101"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="118"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="26528" checksum="A0552BC847E6736E" modified="2024-05-29" version="1">MAGGQPGGNSRGRGGKFRKFTRGGGKHFSRDLRPLDADGNEINMWAAGSKKKDEESSEEDSEEDSEEESDSDEGGAAQAELSRADRKAAAKARKDAAIAKKKAQAVEEESSDDDMPANPNHSKASRNQTKAPAPSADVDEAAEGVKKLTVANNRKERESMEAAQAKERYRKLHEAGKTDEAKADLARLRLIREQRAADAARRDAEREEREAQEAAKKKEIEAKEAKKREAALGPSAKKGKKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN17</accession>
    <name>A0AAD8UN17_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DDHD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_578856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364371.1">
        <property type="nucleotide sequence ID" value="XM_060505174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN17"/>
    <dbReference type="GeneID" id="85389073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF6">
        <property type="entry name" value="PHOSPHOLIPASE C1020.13C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="2">
        <location>
            <begin position="795"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1022" mass="112554" checksum="F2ECF5B865CBC13F" modified="2024-05-29" version="1">MAASEHSHTYGLKCRLAPVSQPSTGGVDDGIPAVAAQFFYSSILPIDDPLSPGTIAGVSDARTTRGSIRPFSLGDNNALEKAWLSFLSNDDIQAHEQLVRDRKLSPNTEKANAHKLSLLARHLAIKHLQKHGGIIQTSTTAGEASDLLPDTPISTCCPELFIDVSTELQNTFCALARKHHPSLGQERVVQEVMMELRGLVASSETRPQFGSVSSSRPRADSTRSRQMEIVSSFSPRQEATSELQRIGREVGNTGLESGSRARSDSRTSEQTSRPSTPGLSTSFRQHAADDGISGKPFVRAGLRQRPQDALATSFPPSEQSKSNEPENQDARRSFTMPEPSRARSNTTQAKIVSDETYRREAVDVVVGISRLHMVSIPALQMKPIYWSPVNDIAMVLRATWFYKDTMLPIPPAVANQLEAGYRELKPHTETWNDELRCAVDVGPLGEEKVSHRLWPENLRQSSDGDKELVSDTRISSDPFCAASCFRGEAAAEGAIDPNLKTASATQQHRSYATYHVIYKDASKAFLLKPSLKPSAYYGRRPVAKIMKGMNVGIPVVRGFDRAVWERTHDKNRPREATKQPASSASNTIEAVGQDVCAACKAEKERGQVTDLVLVVHGIGQKFAERVESFHFTHAINAFRRDVNTELANPIVKGVLRDGQNGIMVLPINWRHTLSFEEGGPMTEEDKAQHVPDGFSLKDIEPGSIPAVRSMISDVMFDIPFYLSHHKGKMINALVTEANRVYRLWCRNNPGFADRGRTHLIGHSLGSAMAIEILSRQPARVPTLDLSTRMPKPDFFEFDTNNLFLVGSPAGFFLLLERGMLQPRRGRVKPGADPADINAPEVTGEAGRYGCIAVDNIYNVLAKEDPIAYLLNGTIDPVYATSLRTAHVPSSATSLFRYVGNAVKSLVPGAAPTPATMAPPPAPKPNFARLPSQLELEVHDFTREEIAERKAYLLNDNGQIDYYLRFGGGPLEIQYLNMLSAHTCYWTSQDFIRMLCMEVGRKPGRENTIPAMRAQKAAKRPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN29</accession>
    <name>A0AAD8UN29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_578907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364386.1">
        <property type="nucleotide sequence ID" value="XM_060505183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN29"/>
    <dbReference type="GeneID" id="85389082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="307" mass="33370" checksum="88A49F3C305A1B47" modified="2024-05-29" version="1">MSPFGHSFSTGSPVMALPPQPAHQASFGMEPFSPQAAPFGQPTAFKRCPAPPAMPAGSLRVAGRKRSRDEAAPNLVTDEPEPHTAPKEPEEEWEYGPGMVLIKKGSYVADAGSQSGTWVEEKAAQDDARKTQEAITRLHEQQERPSLRSNKSQRLTQAVMPNLQAAQPAMASTSTTLSSESSAQPIVDQFTLHLGIGWRRISEDQHIQAAARGWARFIENHYPVSSAIIRLESKGLQSYLVEAAEGFFLFAEDLRQGRLVSRDAEGAMRNLQCSPPAFDGQETLLATESPAAVEPGNMMEADSNMVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP90</accession>
    <name>A0AAD8UP90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_793207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363995.1">
        <property type="nucleotide sequence ID" value="XM_060515773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP90"/>
    <dbReference type="GeneID" id="85399671"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="341" mass="39016" checksum="2671E404B85F002C" modified="2024-05-29" version="1">MCNDQDAPPANNGPVIVADEFTDDSSSERLSSIASSSTSLSSSILQHRIENGRTYHKYKEGRYNYPNDERENDRLDFQHELFLLTLHDKLGLAPPNEPDSKVKRVLDIGTGTGIWAIDFADEHPEALVYGVDLSPTQTTAVPPNVKFEVDDIEEPWTYHQPFDYIHCRAMTSSVSDWKRLFKQAFDHLEPGGWFEMQEGHVRPLSDDGTLTKEHSLSQWANHIEEACNIFGRPFADVPGLVEVMKEVGYVDVTYSTFKWPINTWPKDPHYRTLGQFNHENYMDGIEGFTLAPFTRALEWTREEVDVFLIGVRNDLRNRNIHAYIPIQLVHGRKPEAVPETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPG5</accession>
    <name>A0AAD8UPG5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_619927</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365403.1">
        <property type="nucleotide sequence ID" value="XM_060508161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPG5"/>
    <dbReference type="GeneID" id="85392060"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="124"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="450" mass="49613" checksum="E76D15609A4DF928" modified="2024-05-29" version="1">MSEKKILILGSGLMAKPCVEYLLRNEKNKLTIACRTLLTAEALVSNHPRASAISLDVASPELDSQVASHDLVISLVPFIHHQAVVEAGIRGKTHVVTTSYVSPAMRELESEIKAAGITVLNEVGLDPGIDHLYAIRIIDEVHDKGGKIKEFHSYAGGLPAPECSNNPLRFKFSWSPRGSLLAQLNPATYLQNGRVVDVSCEDLMKQAKPYHVMDGYSFLAYPNRNSVPFREFYRIPEAETVVRGSLRYEGNPAFVAALTKLGLLDTQPLEWLKKSSGGLMLREVFGRAVGAAETDEESLIARIDEICEFPDNNERNRIIDGLRWIGLFSDKPATLRGNLLDTLCVELEGLMSYHYGERDLVMLQHKFIVEWKDGSRDTITSTLELFGEPGGHSAMARTVGVTCGIATQLLLDGEPALNVLGVLAPYNSEICDPIRKLLEKEGISMVEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPG8</accession>
    <name>A0AAD8UPG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cut9 interacting protein Scn1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_718867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365955.1">
        <property type="nucleotide sequence ID" value="XM_060512120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPG8"/>
    <dbReference type="GeneID" id="85396018"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="44878" checksum="06FA6E10B546360F" modified="2024-05-29" version="1">MCGQHDGEELTRSTAVTSVSTPSDPFPWESGIYDAHCHPTDTMSTIEAIPSMRASTLTVMATRSQDQALVAEVAASHGVRSKYELSQGHLIPSFGWHPWFSYQLFDDTVPEAERTYHEGQPDAKKHHYQAVLAPAPEDPDFLDALPTPRSLSAYLADTRARLQHHPLALVGEVGLDKAFRLPQGRTDADESSRDQALTPGGREGRRLAPQHVKMPHQVAVLKAQLALAGELGRPVSVHGVQAHGVLHDTLSSLWKGHEKEVVSKKKRRLVAEGAEDFDSGDELEEDEFGRKDVPSRPYPPRICLHSYSGPAEMLKQYTNPAVPARMFFSFSSAINLGTKAGADKIAEVLLACPDNSILVESDLHIAGEEMDARLEEMYRKVCEIKAWTLQEGVDRIGKNYREFIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPN1</accession>
    <name>A0AAD8UPN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_611663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367726.1">
        <property type="nucleotide sequence ID" value="XM_060507670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPN1"/>
    <dbReference type="GeneID" id="85391569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="35885" checksum="A2F607A6C6742139" modified="2024-05-29" version="1">MPPRLQSLQRLGTASLCLRPAIRPTPSFLPVIQTANLSQREKKRKAKQDPYKHQQALQRKAANQKRQSEIQAEKDASWGDPIHGIPTPFVESFDSAGQAPTTKPVKDDNGNIISDPRPLPTSPGLLNHLVDEKELQAVIDKAYILTKPVKSEIRELADPAMEALADKKHELVHAKAVEALKRILSMDNANSKILLHTNIKRCVEEFGRHNTDKLLTKKPKSALVDPKAPKPPIRGGPDTGSSEVQVAILTAKIRKLSHELSQNRGYKDKHNKRNLRVLCHRRQKLLKYMERSERGSGRWTHLLEKLGLSPATYKEQISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPQ6</accession>
    <name>A0AAD8UPQ6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_729037</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="4 14"/>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367288.1">
        <property type="nucleotide sequence ID" value="XM_060512808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPQ6"/>
    <dbReference type="GeneID" id="85396706"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000168">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Alg11), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="17">
        <location>
            <begin position="111"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="16">
        <location>
            <begin position="355"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00056799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1727233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="551" mass="61472" checksum="3895D1AC7928FEAD" modified="2024-05-29" version="1">MPETCSAPSGQTPFSFGLDPWTLAYVVVPIIAFTPIATYIMFPLLMKGIGSLLGWYLRKKTEGRRAQLLELKTAEQQSFENTQKSSSSGKNNVQAQASGSSEKKDSEWTGVVGFFHPFCNAGGGGERVLWAAIKTTQERYPNALCVVYTGDHEVNKQAMLERVKTRFNIDLHPPTINFLYVSTRHLVLASTWPHFTLLGQSIGSVVLAWDAFQLLVPDIFIDTMGYAFSLGLCKLLFRRVPTCAYVHYPTISTDMLESLDPKAETGSQGVNAGKGVGIRGKVKKFYWKMFAALYSRVGSTVDIVMTNSTWTQGHVQKLWGPYRQAKGRNNPIAVNFPPCAVEELEEAVEVSEASERKREQALVYIAQFRPEKNHTLVIQAFADFLNTKSEAAKDAKLVLIGSVRDDHDSKRVYTLRLLVNELGIKDRVEFHLDASWPEILDWLQRASVGVNGMWNEHFGIGVVEYQAAGLISVVHASGGPKLDIVIEIDGQPTGFHATNIKEFAEGYEKALSINDPLPVRLRARRSAKRFTESEFDEKWIAQMEKLVAMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPU7</accession>
    <name>A0AAD8UPU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_570385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368442.1">
        <property type="nucleotide sequence ID" value="XM_060504298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPU7"/>
    <dbReference type="GeneID" id="85388197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN DAL81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="56"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="329"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="722" mass="80290" checksum="6BF11AA7123F06C4" modified="2024-05-29" version="1">MSNPSAVTRTAPIAIAPKPPRRQNSYLQEAFTNLELFRGGSMPGREIAESVGSYTTRSLSPCESCQRSRVKCIVSEDEDSCIPCQASGSDCSLLNSPQPRKRKLNGDFDDSGKRRRRRQHQPSLSSTTGSSSFLEDMANVGGPTLLKRTLGLQNDRYSQYIGPTTDFEPSLINLSPFNPQDESLLARGTLRKVSDDDTFLLLPDSNTPGHEHILEDIEEIEGLVRPHGRKLVDLYFRIVHPAFPIIQKTVFLEKYERSYREFSPCLLAAVYLFAINWWEHDEELAQVPRPNIPNLERMIRTTLADAIYRPKLSTIQAGLLLSQRPEGDQWAPTAQLVATAQELGLHLDCTHWKIPPWEKGLRKRLAWALYMQDKWGSLVHGRPSHIFSTNWGVQPLTDHDFPDVEWDEKDVEEKLDIERGRTLFGQMVQLSQILAEILDTFYSLQAMQNVTNAGGQGTHLVLGMAKPIQLKLKEWYASLPAAIRMDSTYSSISAPPGRLSSIGYLHLAYFAAEITLHRRIIRSLEATGSAVDSYVQHICRSAAKARLISAMDFVNRLNTSHLRSFWYFASKTNFALIGTFGSLLWATSPGREEADWYRRRLGEYRWTLSVSSKPGEGKGLTMFAMTMLDISTGLLKKLPEKPSMSRSGSVVDIGLGSISSSFANNGLLSLGQSAPATMSLGGFSGLPSADVSNAQSPLSVDSSDDEMYETFAPTSGMASLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPX9</accession>
    <name>A0AAD8UPX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365819.1">
        <property type="nucleotide sequence ID" value="XM_060510417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPX9"/>
    <dbReference type="GeneID" id="85394316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42068:SF1">
        <property type="entry name" value="YALI0B18964P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="947" mass="102517" checksum="7F1EB0F9225F9D5E" modified="2024-05-29" version="1">MPRFSVSFGRRRSTVNSEEFHDEPVETTTKERPTSFRVLERTEVGIGAGQKSFDGGHRLLKATTMAIPPKQYSDLSLEDNNMFADVKNNRNVSTTPSSADLGHQGAQEEWKPSIRKSQTEVPAPKHSSGGFLSKAGRTFSFGGQKKNQVPVDDHPLPPPPLPPQASLEDDHNTRRPRGLTDSTDRTATPPKLSEEDFALDFGSNFGNMFKGSGFDKRASQMTLPGNDKSNMGPRSLTTNRVNQPQPSPIKIDKSIKVEASPYSWSSQHSNDNLLHSGSNSPPATAPPPVPRHGSPLAFRNNVPSDIIEDEDANLLKDSVAASRFLGNSGQPSNPSPPGRFRRNEDAFSTAWDATDSKKEEENMFDNSRAQPPKPPANSQRYTSNNNHSPPRNKVMTPAEFEKYRRDKERDDNTSETVKASDDNRDDDEDQYDDDEDDIEKAKLAAKQRKKQEAHMAVYRQQMMKVTGENPMAGPSGHATRPNLSVSLSTPNLGNLTVPAGPLTGRSEGSEGEEDEEVPLAILAAHGFPNKNKPPARLLNMASNPDLRASTQNQPQPARPGSSMGEGTGPRGTSGGHLPAFARKLPQDPFLGAGLINGPPRESLTFGGGSPAPGAQQPAVVGGLVGVIAGEERARAMRRGSPNVEANVDPFTGAPVGPGNGVPASMVYSNMNGMNGGMGGMGGMPQMQQMQQMQQMQQMQQMQGMPGMPGMPQMPQMPQMMLTPGDQAQIQMTQQMQQFMQMQMQFMQMMATPGGQNMNAMNGMNGMQRPMSHVGTPSVHDSQRQSYFGDSMLEPPRLDPRTRTMSMVQPSSSSWIQPPGGGFAPSIHGGMGGGGYAPSIHAQGAGYAPSIAPSERSNVGLPGRYRPVTQAPQLDSGRRMSVMSGAMGWDQPPKVVQQQENKLPDKSNSNSDDDDEEGWAAMKAKKEKKRGLWRTKKSIGSEIGALIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ24</accession>
    <name>A0AAD8UQ24_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_667662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366842.1">
        <property type="nucleotide sequence ID" value="XM_060511101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ24"/>
    <dbReference type="GeneID" id="85395000"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="23427" checksum="ED9E27DFAFDD98D3" modified="2024-05-29" version="1">MALKRKRSESELVTLFPSPARSESSIESFESPISPSPIYPRAHATPSHLSSRTMKRFRDNRPSEEQIHQRTLNMLYSAQQRNQYPADHETNQSESSPVPATRNTQKSLHSFWNIKSAEPKFPASAPSTDQGMLSPMSCDDCGAGLGASDGAADGMDIDDGYSYGVDHSCGACGRHVCSHCSVTNLGEQRRCLRCVGVAVGVAQNGSGWPSSSMSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ27</accession>
    <name>A0AAD8UQ27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_749678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367936.1">
        <property type="nucleotide sequence ID" value="XM_060513796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ27"/>
    <dbReference type="GeneID" id="85397694"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF149">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="41"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="502" mass="55898" checksum="070278261FA56556" modified="2024-05-29" version="1">MADVLKHHLIKSEHSTVVLVPQPSQDPHDPLNWKSSWKWSTLGAVSLMTFSQGFAPLSLASMFPYLIRDYNSNLEDVIQFTGVTILLLGFSNFIWAPISSSFGRRPVFIVSQLVCLASHVLRAKATTYGSFMGACVLNGIGAGPSETLQPQVIADIYFLHDRGRWNTLYWVVYMGSLMIAPVIAGPMADHVGWQNFWWLNVALTGASIVYAFFGFPETRWIRSQPTQDAVTIEVADETLNPTRTADMDPYLGKGTPSKQQWYLFQRNSSPLKTIWFDLWTPWKLFGFPIVVFASFVVSWSCSNFLILNLTQSQVFAAPPYNMSSQSIGFTNLAVLVGALIGLVTAGPFSDWVSARATARNNGIREPEMRLPAMIPFVIIMIFGNIITAIGYQNHWSWPIIVVLGYASAGIQVAALPSIASTYAIDCYKPVTGPLMVAITVNKNVWGYGMGKFITPWTIQAGFIPAFMTNMALTVFFCACGAIFYFYGKTFRRWTRNSTVHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQD6</accession>
    <name>A0AAD8UQD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_749875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367618.1">
        <property type="nucleotide sequence ID" value="XM_060513835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQD6"/>
    <dbReference type="GeneID" id="85397733"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000078">
        <property type="entry name" value="Protein phosphatase 2C, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="138"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="511"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="587" mass="62306" checksum="9D6B754259871351" modified="2024-05-29" version="1">MFGGGSNSAASKAESDPKEDRKSPSPESDKGASASLKSNDQAASGDKRSGNSSPPGRQQDGAVDKKRRASGVQSKAAGLLAHAKNTLNFSQVGRSNSDVSSQTPLQKLGKQDPALAVPQGQHNNSAGDSVPGPRSTFRVGVWEDRNKKCRRTMEDTHAFLYNFLHTPAPAIDGKKSDSVSDEKDASSQEMVETDNGYFAIFDGHAGTFAADWCGKKLHIILEEIIRKNPNGPIPELLDQTFTSVDAQLEKLPLKNSGCTAAVAVLRWEERVPSDRSATGSQAIAPATAAATKAAKLTSEETADDKAASSGPEATHAKLKSAASRQRVLYTANVGDARIILCRGGKALRLSYDHKGSDENEGKRIANAGGLILNNRVNGVLAVTRALGDTYMKDLVTGHPYTTETVIQPESDEFMIIACDGLWDVCSDQEAVDLVRNIEDPVEASKLLVDHALNRFSTDNLSCMIVRLDKEALLESQNDKENAIGIERPPPNPAKVSESEKIIRETKQKIAEGGAPAIGVSASNSGRGHDPASIDNGDFKPTTLDGTLEEEPGPIDDGESPDVAPDTTPAILPAEVEQTDAAAPKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQY1</accession>
    <name>A0AAD8UQY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366168.1">
        <property type="nucleotide sequence ID" value="XM_060510397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQY1"/>
    <dbReference type="GeneID" id="85394296"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="44794" checksum="0F2DBC4088FE3BF6" modified="2024-05-29" version="1">MANNSSPTCAGLDSFRAFDEYVDKLRSETSLNESSLENCRIQICHALWGESNPDISGIGIFIGYTIEIALGFLLAVLFLGISRYQGQNQKLFQTAVKVGLEAFFDFAIYFAISVAIAVLVMLYKNDYGISTEGFGANEAHMGLALSVTCVLPLFYPVGLLSTKSLQRPAKSRTISNEEPHEKDEKENLRLLLFCLLAVLIFYPFVSKCIHTWKPSQIGTAKGPEGRTLITREEWNRIENMCFGSTSFFTDTEQVILAVFEFLASISIFLFAIWRVSGAVVRKMEEDDVAVGDRRQKTAKLKKMRELIQKAWEQRAIMQISLLLVPVVLGGPLLWSVFRLRTIQAAIAERLESTYSGNDWGFGQIIGIIIFVPIFTEMAFASWRSRSSSQPAAGESEASRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQY3</accession>
    <name>A0AAD8UQY3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cyclohexanone monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_570638</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368416.1">
        <property type="nucleotide sequence ID" value="XM_060504327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQY3"/>
    <dbReference type="GeneID" id="85388226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF2">
        <property type="entry name" value="FAD-BINDING MONOOXYGENASE AUSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="646" mass="71682" checksum="E06E6AA00C3BC310" modified="2024-05-29" version="1">MAAPPQITTDTAAGAAAADFMALNKKYTEEKEKRQRSDGNAQYIEMETDAKFSKLAQDPWVDHEKLNAQTPNLKDGDEVKFIILGAGYGGLLFAIRFTQAGFKPEDIRLVDVAGGFGGTWYWNRYPGLMCDVESYTYMPLLEETGYIPKHRYSYGHELRGHADRMAETWDLTDKAVFRSQIKSYEWDEDAKRWIVVIEQVRGPGESPITMTVRSQFVVLANGVLNHPKAAKNLEAFEGDMFHTARWNYDVTGGNPEDLENVQLTGLEGKRVGIIGTGATAIQLVPQLAKWAKELYVFQRTPSSVEDRGQRPTHPEEWKKIADGPGWQRRRLENFNAFVSGGEAEENLVDDGWTKIKTYKGLVGAPHEKPLGLEDIPGHIGSLLAMDAPRSERIRRRVEEIVKDKSVAEALKPWYPSWCKRPTFHDDYLPAFNLPNVHLVDTNGKGVDHATKNSLVVDGTDYPLDVIVLSTGYRPPAADMAEPSSRSNMTIKGRNGELLSEKWSGKGPSTLHGVLTNGFPNLFLTGPLQIGAAANFAYAQDVLSQHCAYMVVEAMKRAGKSTNKAVIESTLEGEEAYVGFIMQHAAWFSSLSICTPSYMNNEGEKASPEAQMKLARGAPFPHGINAYVKFLEGWRTVGSMNGVQVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR40</accession>
    <name>A0AAD8UR40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_573648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366885.1">
        <property type="nucleotide sequence ID" value="XM_060504634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR40"/>
    <dbReference type="GeneID" id="85388533"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="42336" checksum="FB5802F4BBC6D973" modified="2024-05-29" version="1">MPTSCCPQSNRTAAELADMVRRQYHRFPSDTWEATRLALENPEPHRLFEHIETLISTRKINAILHSNADFRGLMASLYGQRYEWLRDADLGGARWGVTQEEGVEDLAAQAKAAEENSPELEDRKRDIMLRKIVEGGDDLDRWAKVLGFEGASFSRAEVEAVAAKMRTESGLVEGEGRPAYGVGEERESIGGPDHTGCLDGPEGTYGPSTYAGQSSLLVDEEPVQPETVPRAPAEGGEAPRNPFTTEWRARENPGNWKWPQTFDSYYSSNQFIRRSKKYKHPERNSPPDDEDDEEEDEEEDSESDSAQEWEGDNAEGERMPPSALAAWATTIRTRKKSKSKTVTSTRGEGSRSRQKDNGRKGSRLRVSQIDQRSCPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR49</accession>
    <name>A0AAD8UR49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_238102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366900.1">
        <property type="nucleotide sequence ID" value="XM_060501856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR49"/>
    <dbReference type="GeneID" id="85385755"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9508" checksum="B76EF5606E929D8B" modified="2024-05-29" version="1">MNENIAINHTTRSSHPTARTTSHLPIYTYTLTHIHPSTHTQYTDPDLRKPPSQKSKPFFLSTLTPPFLHIHTYTPSLEKQAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URB1</accession>
    <name>A0AAD8URB1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_749564</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368083.1">
        <property type="nucleotide sequence ID" value="XM_060513778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URB1"/>
    <dbReference type="GeneID" id="85397676"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="48336" checksum="F2CE36F9B5065953" modified="2024-05-29" version="1">MAPHANGGTPQSNGGVESRYHASSTQAAIKSEEELAAHNYHPLPVVFSKASGVHVWDPEGKQYLDFLSAYSAVNQGHCHPELVKALTEQASRLTLSSRAFYNDVFPKWAEKIQQVFGYDMVLPMNTGAEAVETAIKIARKWAYKVKGVEQGKALVFSVNDNFHGRTMTAISLSVDPESRDNYGPYVPNIGALNPSTGKAIRYNNVEDIEAVFEAHGKDTAAIIIEPIQGEAGVVVPDDDYLKRVNDLCKKHNVLFICDEIQTGIGRTGRMLCSQWAGIKPDMITLGKAISGGLYPVSCVLSSKEIMLVVEPGTHGSTYGGNPLGCAVSIRALEIMEEEDLTAKAEKLGNIFREGIRAFNSPIVELVRGKGLLNAVVIDESATDGRTAWDLCLLLKEKGLLAKPTHGNIIRFAPPLVITETELRKAINIIGEALKELPTVEKAAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URB6</accession>
    <name>A0AAD8URB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365991.1">
        <property type="nucleotide sequence ID" value="XM_060510413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URB6"/>
    <dbReference type="GeneID" id="85394312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="715" mass="81620" checksum="3DE55623B8783383" modified="2024-05-29" version="1">MPQGQGSSGTVLDPDKRYVGHENAFAIRQRHRAYRTATLFLMHTSSINYEHGKYSAYSHVDDLPRLQTSQAQTPHEVKLTCDTFIYLQNLTPLLIRDSEIISLTPVCSFNTTLKPREDVNPYARPGSKPWVEVPSTQPHLKKILISSNPDWAHHRIITGHDRTYWPSLDVTLDRATPLVDMPEWLGGELGPAAALQHLLPKEPTRREWRSTFTIDVHCRTVFHLLERLHLAAAQKLDQSVEESMKDSDLNILPGSTFGSSGRTAGYDELGRLEFQKVFSTLSCAFETYTEKTRKSCSVFKVIFAKEGMLPPTYHDRVLTLSKDVRNLQMVLLLLSQLKLHFGDILRSHLVWLSQTKADETQHVFKDKESFRDHVERAASGKKAKPRAIRAYLGAGEGVTFGEHLTIDRNQSNRWVAERQKMMAQSKSSADAKGKGLPSTPDRGSRDASTGSTSQATLIEEQMSQLRLDEHPSEKFRGPDEPGDLIDPETLAVERERTPWYQDSSVLSLKEFFRKFPKTNGDHWSEQELSTMEDNMMARVYGPKRKDWLPKNKLTYNGTWHAETIVLSLHHLATELFERMDQSLVRESTESALFESHLLPKSQVLGNFLNLSSVLAVSKRCCPSCNMMVEVTEASRKMRILRPGDHSDWFSTLYPHGFQRKSFPKWRLESLKRCQEDWERPYRKPNFQGLAAAEDRDRRKVSLMPLAAITCSTSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USG8</accession>
    <name>A0AAD8USG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_651224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365645.1">
        <property type="nucleotide sequence ID" value="XM_060510437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USG8"/>
    <dbReference type="GeneID" id="85394336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000328">
        <property type="entry name" value="Lactamase beta 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="285" mass="31427" checksum="B44EAEB08A97DA20" modified="2024-05-29" version="1">MASQLVALPEIERLSPACIRILGGNPGKFTLQGTNTYLVGTGSRRILIDTGEGKPSWIAAVKSTLEQEQATVEKVLITHWHHDHTGGIQQLLQLSPSSEVFKNQPEEGQSDISDGQKFSVDGVSLTAVFTPGHTVDHMAFVLEEEDAMFTADNVLGQGTAVFEDLTVYLDSLERMQSLFKGRAYPGHGPVIDNGPSKIQDYINHRKAREEQVIRTLRTARQGSGIEGDPYAWTVMELVKVIYADVPEELHIPASGGVIQILEKLAKENKVVQSDERWKLKDRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UST1</accession>
    <name>A0AAD8UST1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_718405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366711.1">
        <property type="nucleotide sequence ID" value="XM_060512068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UST1"/>
    <dbReference type="GeneID" id="85395966"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF5">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27573" checksum="239ED16BEF18F0E1" modified="2024-05-29" version="1">MNDTDTKTAPADTPTTATTPAALTELFEKAEAGFPPRFREHGWYLTVIASLIGSGQQKLAGNLYTHLVSQPQYQTPAERQVLVRRLREAMVKCIIINGIPVVIEAVTSVSEVEKPEDTDQSCSCEDWQIGPETSKRAAAVLKVLYKSEVGAPVEVLHAHKDIPWISVNVSYGLFLSDHRILDIQETELVVTPAIMTQNLQDPTYWHLRACLRVGMEPEEVEAIHKVIELIAAYGGKTLDVKRVKDVTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTL5</accession>
    <name>A0AAD8UTL5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-D-xyloside xylohydrolase</fullName>
            <ecNumber evidence="5">3.2.1.177</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_570282</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.</text>
            <dbReference type="EC" id="3.2.1.177"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.177" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368657.1">
        <property type="nucleotide sequence ID" value="XM_060504283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTL5"/>
    <dbReference type="GeneID" id="85388182"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061634">
        <property type="term" value="F:alpha-D-xyloside xylohydrolase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06593">
        <property type="entry name" value="GH31_xylosidase_YicI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000053">
        <property type="entry name" value="Alpha-xylosidase YicI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007940">
        <property type="entry name" value="PRK10658.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF4">
        <property type="entry name" value="MYOGENESIS-REGULATING GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="8">
        <location>
            <begin position="59"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="7">
        <location>
            <begin position="282"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="9">
        <location>
            <begin position="617"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00052064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="765" mass="85344" checksum="294BFAA777EE63A8" modified="2024-05-29" version="1">MVRLRDGMWLPAEGTATEYAEEVYYTTEIEGGKGLSLLCPTRKIKTRGHTLNASTVTLDVKAEFDGVISVEATHWAGALNKGPHFELFPDGRPPDAETKVTKGDKGTTTLTSGSLSATIHPDFDIQFHSTDGAKRLTSLGSRSVGLAYNPAPSTPMQTGDMRDFKHYMFTQTTLGVGETIHGLGERFGAYNKVGQSISLWNADGGTSSEQAYKNVSFWLSSKGYGVFIDTPGRVELEVGSERCNRLQTVVEGQRLKWYLIYGPTPKDILKRYTTLTGRAGKVPSWSFGLWLTTSFTTNYDEETVNTFLEGMKARGSPVDVFHYDCFWMKAFTWTDFVFDSERFPDPKAQIARLKESGLCKKVCVWINPYIAQHGEAFKEAADKGYLVKRKNGDVWQWDLWQAGMGLVDFTNPDACAWYEEKLNTLFDQGVDAIKTDFGERIPTLDVEWHDKTIDPVKMHNYYAFSYNKVVYEALQKRYGADEAVLFARAACAGTQRFPLQWGGDCESTPEAMAESVRGGLGLGLSGFSFWSCDIGGFEGYPPPWIYKRWVAMGLLCSHSRLHGSSSYRVPWVIDDDDKSEEGCSQTLATWTKLKARLMPYIYAQAQTAVERGLPLSLRAMCIEFPEDPTSWYLDRQFMVGDSLLAAPIFEESGEVEFYLPKGKWTSFFSGEHREGPGWFKETHGFGTLPLYVRENSILVLGAETAVGAVYDYVRDNEVRLYQVKEGATATLVGSDGKEIGVLEVGADGKLKDTVLLNGKISIKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVD1</accession>
    <name>A0AAD8UVD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_129041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368538.1">
        <property type="nucleotide sequence ID" value="XM_060501199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVD1"/>
    <dbReference type="GeneID" id="85385098"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544:SF3">
        <property type="entry name" value="SPRAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="431" mass="49204" checksum="44210D98ADA55306" modified="2024-05-29" version="1">MLLNLFRMTPFILCARKQGATAGQTILRSYFPSPSFRDAWETKNWLLMLAYTIYYPSYSVIGFKSALLYESWDDTDIRLHVNDWACYTLIAFYSVIQLYLIIVFVYLWRHKTGLQWDPVSIADILVLFRHSNVLKYFEGSSIAQRQSMFENLEKIPMYLKYWKAENGKYWHGFGTDDIESEDISPNVRADSSNPIGEPGIAQSPVELRDLTQSGSSHPDQSPDASSHLSGDSKTSPVSMDTLALIRYNSAWAVANPMSVYCHFFLAFSLMILFTVGISITPSITPDRGYCWAPQNLSRNWANFLLDVILTTAVSFLSDFWAALSLFVVHTEPLARMARPSESGEPAKYTLLLNYTSSFLPIRIYNAFTNKHWKLVRIMFWELLQRLFPTLIGTSIIVYSRVNSDSLSSHSEGLPLHRRHRVLVLNQSASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVZ6</accession>
    <name>A0AAD8UVZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_717183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368361.1">
        <property type="nucleotide sequence ID" value="XM_060511918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVZ6"/>
    <dbReference type="GeneID" id="85395816"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="3"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="30207" checksum="7AB877FED0B3CBDC" modified="2024-05-29" version="1">MHDWSWQVPFLLSHNLRVISIDSRGQGKSSAPAPDPKIRTWPGVARSADPDVIDYYPQSTAEDMLTLLSHLGITKNLIVISHSLGEAAGYYIATTHPDLVKASIGVDPIHAFSNAVRERDTYLFNDPDAQDKIIPTLIEFFGTYCYSPECPAWQKTWHLRRMAQFDKAVMYALCWGGWGDAESLGRQENAVKAFAGKLKCPRLTLGSNDWYVGTDRDHLPKGDEALDEIVVIEGKGHWFHQLESEEFNGHLERWFQKIGVLPAVEAGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW78</accession>
    <name>A0AAD8UW78_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP proline-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_571051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368224.1">
        <property type="nucleotide sequence ID" value="XM_060504370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW78"/>
    <dbReference type="GeneID" id="85388269"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="286"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
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        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
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        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
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        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="67878" checksum="334FF80B25457FB3" modified="2024-05-29" version="1">MAAPKMTKNQMRRAKKKEQKKTQTEVASNTPEAKDDEKKPEETGATPEPTGNDLEVKNEPEANAKVEADGPADDEFNFDDERFAAFKDIFSKFGVAIDEDEVSKEANAGNTGEVIWDEDDIPSEDEEASGQTKLSKKKRKQLNKLSIAELKALVKIPDVVEWQDTSSTDPRLLVQIKAQRNVVPVPGHWALKREYLSSKRGIEKPPFRLPKFIAETGITEMRDAVLEKQEQQSLKQKQRERVAPKMGKLDIDYQKLYDAFFRFQTKPELTRFGEVYYEGKESEVDFQHFRPGDLTEATKEALGMPPGAPPPWLINQQRFGPPPSYPTLKIPGLNAPPPPGGSWGFHPGGWGKPPVDEFNRPLYGGDVFGLTNQAGAQIAPPVAAPLATGEPVEKTLWGELQPRDEESEEEDSEEESDEEEEDEEDGPSGGLASPSGIETSGGMVSSVPTDYPGHGVETSVAGEMDLRKQRRGFDTEESSHPRSAYQVIPERQQRTEGFFGSDRVYDLNQQKANMPVLGQEDDSRKRKKPGDVDVALDPDALLNNDGISKDEVRRRFEEGKREEGLGAKWAYEEDLSEMIAQESRKRQKVDEKRNDEKKKQSKYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWE8</accession>
    <name>A0AAD8UWE8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7719 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_749857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367595.1">
        <property type="nucleotide sequence ID" value="XM_060513832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWE8"/>
    <dbReference type="GeneID" id="85397730"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056136">
        <property type="entry name" value="DUF7719"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846:SF1">
        <property type="entry name" value="DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846">
        <property type="entry name" value="YALI0B21296P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24841">
        <property type="entry name" value="DUF7719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7719" evidence="3">
        <location>
            <begin position="162"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="25665" checksum="5CA1D67217B58807" modified="2024-05-29" version="1">MAKKGTKEKRVKDPKGIPLAQPDRSAPSEATLLQMAQDRGLFKQADKDPRNKNLPKGAVRIDRPEAGDSDDDEGDDEEALLSPLMDRIMDTLLWTVSLAMVHGTLDVLVQNQYAKEIEWPNVFSRTLIALIVLSFLFYNLHAFPSSPNLVPGLPARYQHPIRQAIFFVAGVWAGCHLIYITNKFSYLYIMKQAPTLGCVWIWSVLELDLPVAVASLAVAGAYLLQGGYAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWG9</accession>
    <name>A0AAD8UWG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cation efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_749012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368661.1">
        <property type="nucleotide sequence ID" value="XM_060513708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWG9"/>
    <dbReference type="GeneID" id="85397606"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000001">
        <property type="entry name" value="Metal tolerance protein 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF13">
        <property type="entry name" value="CATION EFFLUX PROTEIN CYTOPLASMIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="184"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="10">
        <location>
            <begin position="395"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56506" checksum="5DE386AD8DBA8C55" modified="2024-05-29" version="1">MQTPRESQDGVQPSSIASARGNSVGHSESNSKAEANKEHNEHPKDNADIISPAQPSGTDDKAVTEGLFVSTSNDTAANKSDVVRTSSKRGGGGDGPYSNVDATDASTVDTYRPDPYDFGRHRRDNVSKKQMKIEHPKGNKRKLKKFYNRQNELIDQFLGAEDEERQQVAEDARMGPKIKFAVNASFTVNFCLFVIQLYAAVSTGSLSLFATAADAFMDLVSSFVMLITSRMAARPSVYKYPVGRTRIETIGIILFCALMTTVAIQLLVESGRSLGEGKRASEQLHIIPIVIVGVAIFAKASLMIYCFAYRKFPSVHVFFIDHRNDIVVNSFGLIMSVVGDRFVWYLDPIGAICIALLILLSWVSNAFEQVWLLVGKSAPRDFVSKLIYMAMTHDTRILKVDTCRAYHAGQNYYVEIDIVMDETTPLRISHDVAQELQRKVEGLSDVERAFVHVDYSEAHDPHEEHKPLYERLSKKPQKRTLKDILLRTKKETADVTETEISSGRNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8J5</accession>
    <name>A0AAD8X8J5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_183646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000215">
        <property type="protein sequence ID" value="KAK1707149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357997.1">
        <property type="nucleotide sequence ID" value="XM_060501538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8J5"/>
    <dbReference type="GeneID" id="85385437"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102049" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="11156" checksum="BE5F2F4DE0D5A8DF" modified="2024-05-29" version="1">MAPLQSRQIHFFFFFFPLLLQGKFQPPAHWAFLPVPILQLSWCCWQAGAASDCCCVRRSWLLVVVARLVLASFVFHTDSCHPIIPRNPLHHRLVSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9H7</accession>
    <name>A0AAD8X9H7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_119612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359077.1">
        <property type="nucleotide sequence ID" value="XM_060501142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9H7"/>
    <dbReference type="GeneID" id="85385041"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="35204" checksum="FE9F13EFF255065B" modified="2024-05-29" version="1">MRRKDRSVYAEPSRSERISVYRDSDCKAIFSGLNHGRLRQRKAIASVVRERGLRVPGFSTERLITILRSLQKDRIFEHSSYACRAFPELFLDEEPISPAAASAPPSATVPAQTAMASIGRPQKDLVESFERLYTTGIYSDLTISSVAKTYSVHRAIESSDGSIHLPDDEPCVVDMMMQYFYLLDYRQSLYTDSLLQSPELEPSKAESITCLLLHAKVYTIAEKYAVDGLKDLAVAKFKDAAAQAWEPNDFLCAATEAYTSTIDTDRGFRDAVIEIFAVHEDLLDDEEAKTTIKSLGSLPYDLLLYFHREGNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA61</accession>
    <name>A0AAD8XA61_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit BET3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_723071</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360219.1">
        <property type="nucleotide sequence ID" value="XM_060512525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA61"/>
    <dbReference type="GeneID" id="85396423"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit BET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1715076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="189" mass="21715" checksum="403EE1CAA4FB6BA7" modified="2024-05-29" version="1">MAAIVERVSRSSTRIDKVNAELVTLTYGTIVAQLCKDYDSDYVEVNKQLDKMGYNIGLRLIEDYLAKSNTMKRCANFRETADVIARVGFKIFLNITPQVTNWTTDNKQFSLLFDENPLADFVELPDDERAQDELWYSNIFCGVLRGALEMVQMQVEAHFISDVLRGHDTTEMRVSLVRYIDDELPPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBA3</accession>
    <name>A0AAD8XBA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_758001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000195">
        <property type="protein sequence ID" value="KAK1708420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358298.1">
        <property type="nucleotide sequence ID" value="XM_060514971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBA3"/>
    <dbReference type="GeneID" id="85398869"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF2">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="21"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="36403" checksum="703E67174510DF6F" modified="2024-05-29" version="1">MLGKRKRFDTFEDSDEAIQSRCIKFIVGPEKKEYTVHEARFTNLSPALHALLTAGFQESRRGKVVWDDTDPVTFVLLVQYAYRGEYSLPDSNGVTTIPEENETPEDGDTPKNLPRSMQGYFWAAGHRGSQHHFVNDRFFPEMSCDEKPPGMGQAQCILRKFTGIEAFEKACRHVEHLRPMYMLHVQLYFLADKYIIEDLKEMCLARVRHFLSECPGTFQLKTILLESVPVIYSQTIHGDSLRRLITHYFLANMNWIDTGSRFKALRRSTPDFGLDLLDEIPHSYWTELSEGPNEPAAEAREDQAQYQATRRTRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBU4</accession>
    <name>A0AAD8XBU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_592752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358240.1">
        <property type="nucleotide sequence ID" value="XM_060506560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBU4"/>
    <dbReference type="GeneID" id="85390459"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010421">
        <property type="entry name" value="TrcR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06242">
        <property type="entry name" value="TrcR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="700" mass="78432" checksum="0FD6B0FE33657AE6" modified="2024-05-29" version="1">MPSPELNSRSSFPIQSPEIDNIQFPRSWEMAWEAAGQTNFERAQAFLFFYRGDDASTNSELRSIAANPKHRDVASLAVSVQINVFGNRHSTFNTTSLLQWMRFVLIKSQALTSSKTNAVRDFFFDPSVARNLPQLPQDPIVYQYPAAPLKIMIIGGGPTGLASAIALAEKAGPRVEVHLYEGRWIQQRGSSFVSYPPKARRRDQVVTLQDTVTDLMSDRTRQAVFGGNSERVWPGSSNLQIRKLEDGLLRRAQDSQFRGLIFLHASQVRQDNLSEYGDFHLMLGADGAGSWLRSAYFPGQEEEVGKSYALGVAFDRPRGLPFSQPINIFLTMGQTRYLLNASDFDGTGYLNMQLTEAEWHQMVSVDGHPCTFGRPSCLKVDDCLPHGFEENQVFAPSQQPDSPLWKAILDGLELYGFKQCEVKNIVRIPIVVRRINKAVEQVPQGDSAALRRPHGLVAVAGDAAMTVHFWPGRGANSGMKAGIAWADEVARALFHRQFVGLQTSSLGMYDDFLQKLQEREHGGRSLPIVKQTGDPDMMAWLMRNARLIPQHVAMEWLVGQMRRDGVRIQRRADWAFEQINNLEPQLREILEKMDAVTIQEMAATFPWPTREMAGAEVLPERSVVDACLSGQRPTEISKVEKQTKPKKQDKKKKKKSAEISVSASEISPAFLASLATHNKPAQRSSWRSFSFSRTPQAVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBV0</accession>
    <name>A0AAD8XBV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358868.1">
        <property type="nucleotide sequence ID" value="XM_060509486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBV0"/>
    <dbReference type="GeneID" id="85393385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="69" mass="7524" checksum="CF5EEA13970F7431" modified="2024-05-29" version="1">MLTRPEGKVVQRRSAKCSSGVGRGSGPRACRSVWEASPEQYGRLGQTIVSVSEILSNEDYCLVSSNCCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBY2</accession>
    <name>A0AAD8XBY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Six-hairpin glycosidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_761124</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360686.1">
        <property type="nucleotide sequence ID" value="XM_060515178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBY2"/>
    <dbReference type="GeneID" id="85399076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.420.10">
        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035398">
        <property type="entry name" value="Bac_rhamnosid_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF4">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17390">
        <property type="entry name" value="Bac_rhamnosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041947224" evidence="1">
        <location>
            <begin position="25"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-rhamnosidase C-terminal" evidence="2">
        <location>
            <begin position="699"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="806" mass="86146" checksum="14EF525B2395207D" modified="2024-05-29" version="1">MLISSNTGARVAGVLFCLLSSVNGRHGSQRPHLAQKSTLSSSTNGTIVFGSNETTALTSDGTTASIVVLDYGHNVEGFPTFEVISASGDTSSFEISFAESKVALDSYMSDGPLPLAAAMHTYRVNQYNITAPSLITNRLIQGAFRYQKLNLSSAGSLQLRNIGVKPTTSTIPVTQLPGSFECSDEDLTRIWTTGARTVQLTEIPKHSIPDFLQVSDEGAYAESQAPQGLAGAVAAQLLNYRLDIQAKPVKGGFGVSVLCDTLNSCVYLSFNLDSHTITAHAGSTTMTSITVTLNALPVLNLTQTSRYFGSFGFGASFGHAAYFRNLTASTPTGETIYTNSLTSPSFLPDFMMGANSADRIVDGSRRDRIAYTGDLDVALDVALGAAFASTFGTSFIDGSLDLLGSYQATPGFFIPTAKIQQAPLMEPLNTNLTGLIGYSFNFLSALAQNYEMRGNISFAKQWAPKVSKMLDWANSQTLPNGLFNLADESFGGDWNYYDTPQSGVVTKFNVVYAYALQQSLPLLRDAGLTTTVYQTRLDILRSTINTNLWNQDLNAYTLSSNFTTGFAQDANALAILAGVSPSPNTTASILSTLARDLILPSGPLAFSNSTSSAGFAQKISPYASSYHLRAAFSARDASTATTLLKTLWAPLAHPKHENYTGCFWETLNPDGTPGLGVATSLCHGWAAGPTAELSRYVLGIQPIAPGFVEWKVEPQTLGLEWAKGRYPTVLGDVAVEWRFECGMLTMKVETPAESKGTIYLPESLVTSLEKSVIRVNGVVKNGTQFEVNGGDAFVLTQEPLGAGLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC67</accession>
    <name>A0AAD8XC67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_657324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000184">
        <property type="protein sequence ID" value="KAK1709391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358525.1">
        <property type="nucleotide sequence ID" value="XM_060510955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC67"/>
    <dbReference type="GeneID" id="85394854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42095:SF1">
        <property type="entry name" value="YALI0C12166P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="16528" checksum="7AF1C101B60D833E" modified="2024-05-29" version="1">MPSQRPFFLSTFFNSFRQQSPSATALSSQQPNKHTTQASSSSYATQSAASAPRAISSNTSPSSGGNNANASSTTRSTPGVVNQYPLHSPRGGIPIPGSANRRRGSDSSSEGFRDVLGADKWYIGGRTAGGEEKFFKLGVVRRVRSNDGLSLDRLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC94</accession>
    <name>A0AAD8XC94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361972.1">
        <property type="nucleotide sequence ID" value="XM_060505729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC94"/>
    <dbReference type="GeneID" id="85389628"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="310" mass="34310" checksum="52757B81A5A4A37F" modified="2024-05-29" version="1">MDHLPSEPTSPGRRHLMRPVLLVLAFAFALFVSLVQILTLTAGTWVIRDSNGAQRLGLSSLAIVEFDGIVPSQTNPYTYLVTMHQFASSFAYTYPSKSLAGTLDSSPHLPYDLGAVAHALHLPESEWACYHFAQDACQNNPFLSAFRNSWLILPTATANLALVYALVVVSYLFVTELLIAVQPSWLRCQCYFSCIKRVCPCPRGTRAEIEALPAVFWDRYRGWCWFMLPAAAFLPVFTLGGNGMLLKEYVNRPRGLEGDVNGRFGTGFVVLQTLCFAASVAGTGCMVLRRRLGMKKSWMEEQGVGLKRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD66</accession>
    <name>A0AAD8XD66_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_653560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362917.1">
        <property type="nucleotide sequence ID" value="XM_060510628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD66"/>
    <dbReference type="GeneID" id="85394527"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="529" mass="60146" checksum="30593403588F38E1" modified="2024-05-29" version="1">MSFLILGSALPFVAIFLLLGAFLFQTLYIIFTGGLSKVPSAHWTCSFSPVWILWQRYHGKELKAVLAAHERLGKIVRVAPQEISISDYETGVRQVYNAGFEKPGYFDFFQYYGQRNSFASRSRADHAACRRRVSSSYSKTTLFASETLSKVTHNIMYQRLIPVLQHHSAHGQPVELLRLCYASGLDMLNCYILGLSSGPDFTRNPELTEKWLEHYENRYSPQGFWLQELPKLYHGLRKIGLDVMPRKHYESTEWIENWMLEHCDRSEAVYRRMQNGEQPAAEDIPVVYNQLRKAMSNLKDGKFLDMQASEELSRISIASEIFDHMSGAREVFGLVLAYAVYYLAQNPAQQEMLKHAVAGLGMHVNQVGNSDADSLPSPQTIESIAYLQAVIKESLRMRPNSTPLPRITPHDKSVSISGVDGIPAGTRVNCFQWFLHRNPEMWTQPNAWVPERWLDPNGAERTDMPPLWAFVTGPRACIGTQLTYYLFGYILAGLFSNFNVQIARPETYGRHTPGSLEDELFVLMTPIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEC0</accession>
    <name>A0AAD8XEC0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363251.1">
        <property type="nucleotide sequence ID" value="XM_060514383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEC0"/>
    <dbReference type="GeneID" id="85398281"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="24418" checksum="480A745AA0A097BB" modified="2024-05-29" version="1">MQRLGFSRSSAAPATFEEYLEVVLAEKDRKIQQNAAVLQAIRLKTEQQKMARQKGGGGPGLPSSREPASIQDPASGSGPSLATANPLYGADPCWNIQYTKITDRAQDRCAEWPTLAVYKEASRRASNNKCLPPPKQRNVQDRIDLALGDVAWKEHASIHQEHVIGSDDRRGIFSPGNDASTETGPNNHIDPNSLNDWTREIIDEIILETEGNETSITDEDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEM6</accession>
    <name>A0AAD8XEM6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RTA1 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_580715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363566.1">
        <property type="nucleotide sequence ID" value="XM_060505374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEM6"/>
    <dbReference type="GeneID" id="85389273"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14140)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="35138" checksum="1C38425B3E8136A6" modified="2024-05-29" version="1">MSANDTTTRRPFRECTEVSQLCPVEMTVLSYYPNFGANIFFAVAFGLIVLVSATIGTWKRTWTFMALATGGCVLETVGYVGRTLLHENPWNKDAFQMQICTIILGPTFICAGIYLTLKHVSANLNPSLSRVRPRLYPLIFLPADLTCLIIQAIGGGLAAAAGQTNKKLLDGGNQAIIAGIVLQVVVLMLFGITGADYWIRVRKWAHGADTSDGDVALYHAKRFRSFIYAVTVAYACVMIRCIYRVAEMAGGWGNHIMQDEVSFMILDGGLVLICVTMLTAFHPGLFFPQMANARKASIGEKSEATTTSTPENTKIESGRESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEV4</accession>
    <name>A0AAD8XEV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PH-response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_529721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364717.1">
        <property type="nucleotide sequence ID" value="XM_060503319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEV4"/>
    <dbReference type="GeneID" id="85387218"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF7">
        <property type="entry name" value="PALI-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="25533" checksum="34BCF5C97AB8FA29" modified="2024-05-29" version="1" fragment="single">MAVTGFIHHFGTFLLLVATILLVITSISAPVVHNISLLTVKLGDTSAGNEITFGTFGYCVRGGSDYGSDQCSRSRIGYSPTDIIAEADATQYSNLSSNVAEGLTRVMVLHPVAAGVSFIAFILSVGAGMFGSLFAALVSGVAFIITIVALICDWVMFAVVRRNVNRDGNGSSAHYDVALWTLLAAAICLLLGTVIVFFTCCSGRLHKRRQQRSKVDNYSPPATHTTYRRRRFWQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFC7</accession>
    <name>A0AAD8XFC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_632145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361495.1">
        <property type="nucleotide sequence ID" value="XM_060508946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFC7"/>
    <dbReference type="GeneID" id="85392845"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041913217" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="54" mass="6159" checksum="1C167432CE926B51" modified="2024-05-29" version="1" fragment="single">MRRNAISVLSLQLVPLAIPWPSLRAVTWAWCLTAEGALRAWLMSTCQFGRFKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFH1</accession>
    <name>A0AAD8XFH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rare lipoprotein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_631540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361630.1">
        <property type="nucleotide sequence ID" value="XM_060508909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFH1"/>
    <dbReference type="GeneID" id="85392808"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22271">
        <property type="entry name" value="DPBB_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049818">
        <property type="entry name" value="Expansin_EXLX1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041144">
        <property type="entry name" value="expansin_EXLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="PHL pollen allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042043110" evidence="2">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="219" mass="23260" checksum="0EC06951B32B1ADA" modified="2024-05-29" version="1">MHGIISLGAALAVMIQGTAAATSAVATWYGGNLNGGNCLFSGYTLPSSVLGTALSYTNYNGNCGTCLNVKGPKGNTIKVMVVDKCPSGCGNGQLDLFPDAFAKLDDPNKGQISVSWEQVPCGITSPLIVRNKEGTSKYWFSMQVVNHNYPVTKFEVSTDSGKSWQPTVRQDYNYWQKSSGDGFLVDTVSVRVTCSNGKQVVVNKVGTKEKASFTASGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGU4</accession>
    <name>A0AAD8XGU4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16 17">Phosphatidylethanolamine N-methyltransferase</fullName>
            <shortName evidence="16">PE methyltransferase</shortName>
            <shortName evidence="16 17">PEAMT</shortName>
            <shortName evidence="16">PEMT</shortName>
            <ecNumber evidence="16 17">2.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_750004</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16 17">Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64573"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="2.1.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16 17">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16 17">Endoplasmic reticulum membrane</location>
            <topology evidence="16 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16 17">Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16 17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.17" evidence="16 17"/>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367509.1">
        <property type="nucleotide sequence ID" value="XM_060513860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGU4"/>
    <dbReference type="GeneID" id="85397758"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004608">
        <property type="term" value="F:phosphatidylethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2840:FF:000006">
        <property type="entry name" value="Phosphatidylethanolamine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03217">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016219">
        <property type="entry name" value="Phosphatid-EA_MeTrfase_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138:SF0">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000383">
        <property type="entry name" value="PEAMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51598">
        <property type="entry name" value="SAM_CHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16 17" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 16 17" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 16 17" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16 17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13 16 17" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="14 16 17" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16 17">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00057332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1727454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="967" mass="109142" checksum="0B9761CFC5994541" modified="2024-05-29" version="1">MSSSAAPLASDAGSLRQRQRRTSAAGNGEDGLNPSTVADDQSDDLTQKPNKTFGRTPDGTVFTVPTTHDMVSQLLDPRQPKNLSDVLVLAILALQIVAAYFVPGNLKRPLFALVFLFWRASYNIGIGYLLTIQSNHRRLETWAARWKLFEHPASGKQPRPWLYNMLKRELEAKIPEDYEFEKAPMEYNTWLVFRRVVDLILMCDFVSYCLFAVICGHTPAGENPFVGVGRWSIGILLVLFNLWVKLDAHRVVKDYAWYWGDFFYLVDQELTFDGVFEMAPHPMYSIGYAGYYGISMMAASYEVLFISIIAHLAQFAFLVVVENPHIEKTYNPPAPRKRTASTPLTGQPELVAVNDEIVVDQAATTQESSPEAPAQVHNLIGLNNLDLFRITDTSVLLLGFYMAVLTLVTPSTSLYQVLFLLHALFWRVWYHLGLGAILAWQSRNKFWTRHFLKYGESHTEAWNQWKGMYHLSSVMCTGSFIAACWKMYSPPEDWAYGWVLLKHVVGAGLVSLQVWTFISVYDSLGEFGWFYGDFFYDSTARLTYKSIYRFLNNPERIFGTAGLWGSALITWSRAIFVMALVSQLFTLGFINFIEKPHMQKTYGRGIRQEAGLTKFIKRSLPPPVQGWQRGVDKVIDDTAQFIEEFLDTARPKFASGIKTIVRDTSALFNKYPARLTVTRLSPDLAGLDPKLYSLSVEGTPSSLSAANERATGKEGLTARFQRGVETMIFEYGAPLKVKWRAPAKHDSKDWIGLYMVTDNRSREATEVSSLGRWVPTTPGSYDAATADKAILVPDRPAQKQDASDPDIVEGEVIFEGDRLWWTQGVFEFRYHHAGNHHVMTISQPFEIRIGKFDEDDVEVDANGMYEKAVEQALLPLVQNCCDRDHDIAPTTVDEPFGGHVERDGKYAKRIVYAIHQMFGIEFAPAIVPADGNVKKMAWRICNAKQVLAPYSLSHSKGNSTPTTFEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI68</accession>
    <name>A0AAD8XI68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PITH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_571159</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368257.1">
        <property type="nucleotide sequence ID" value="XM_060504384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI68"/>
    <dbReference type="GeneID" id="85388283"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.470:FF:000003">
        <property type="entry name" value="DUF1000 domain protein (AFU_orthologue AFUA_1G09230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="3">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="23974" checksum="DFE8BD9AFB7F784A" modified="2024-05-29" version="1" fragment="single">MSHCHDEHHDHSHGGHDEHDHSDDITPALQHSLYGHINFDKVTALNEAAIGSARAVVKKTWAERLDAEPEVVSDCDEQLLINVPFTGQVKLHALLLRTSDSPSAPRTLKIFINRDDLDFASAEDAHPTQEFELSRTGQVQEIPVKRSLFGRVQRLTLFFEDNFGDGEEDETRVSYLGFKGEWMQLGRAPANILYEAAANPSDHKVKGTGVNDVGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI99</accession>
    <name>A0AAD8XI99_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364450.1">
        <property type="nucleotide sequence ID" value="XM_060508361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI99"/>
    <dbReference type="GeneID" id="85392260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042176024" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9948" checksum="27E9F138BD727DC2" modified="2024-05-29" version="1">MMGCCWFAWLCSDFAAGWRVCRSLAFSKLVVCRLCNIILRLSEIQELGELSAHHRLESPLIRIGHSSSRVTLIQSQVLRPLALLAYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIK9</accession>
    <name>A0AAD8XIK9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_696992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366278.1">
        <property type="nucleotide sequence ID" value="XM_060511376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIK9"/>
    <dbReference type="GeneID" id="85395274"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="39081" checksum="E7AB444A7BB16E2B" modified="2024-05-29" version="1">MTTERYPDELIVGDDTEDETRSEVGSIASSSTSLRESVLDYRLENGRTYHRYKDGKYTKPNDEREMDRLELENELWLISLDFASGVAPPAQKDSKFVCSRALDVGTGTGSWAIDFADDHPESEVIGFDLSPPLTEYVPPNLKFEIDDLEEDWTWSRPFNYIHSRVMTGAVNDWDIYLRKIYKNLEPGGWVELQELDIFVTSDDGTLTEKHALSQWSKLLHGASEKLGRPYIDPKSLDLKAAGFVDVSITTFKWPLNEWPKDPKYKQLGRIQLENGTTGMEAFTMAAFTRAYEWSPEEVNVFLVDVRNDLRNKAIHAYMPAYCIIGRKPEKGELEAKKEESIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ37</accession>
    <name>A0AAD8XJ37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_228414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367193.1">
        <property type="nucleotide sequence ID" value="XM_060501791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ37"/>
    <dbReference type="GeneID" id="85385690"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF14">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="38916" checksum="EDEE1C8B40DA466B" modified="2024-05-29" version="1">MSELKEILVIGGTGAQGRPVVKALAETKQYSVRVLTRNVDNARAKELATLPNVTLIQGKQDNQQDLHRAFKGVYGAWVNTDGFTLGQKNELFYGIRAYEIARHEGVQHYVWAGTDYALKKSGWNERYHWGHNDSKGRVTDFILAQGQDGMKSSVLTTGPYMDMLLDGMFPPTEQPDGSFLWVNPAKDGKIPLIALEDVGIYSLWLFDNLNESAGLNLEVATDEVSFADIARIFTEVTGKKGIHKSVPFEEYAPLAEPYPGAYVNFSVGPEVARDESDMTWRQNFGAWWRFWGEGIVNKRDLELLDRIHPGRIRSLAEWMRKTGYDGSSRPVLKGVEDWRSKLQAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJL4</accession>
    <name>A0AAD8XJL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_609154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368483.1">
        <property type="nucleotide sequence ID" value="XM_060507517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJL4"/>
    <dbReference type="GeneID" id="85391416"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="74" mass="8039" checksum="F461526B8817B355" modified="2024-05-29" version="1">MSMLLLLNPCPLLSFTYPYVHIAFPSTLLWLTPHGSCTDQQVPASQPSPALVAIWLGSAEALTAWYVVPSQPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJN5</accession>
    <name>A0AAD8XJN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_226336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367075.1">
        <property type="nucleotide sequence ID" value="XM_060501773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJN5"/>
    <dbReference type="GeneID" id="85385672"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="45356" checksum="359EAEA6ECF0D47B" modified="2024-05-29" version="1">MDGAQRDSFLLSRDRYPQKEAVSFTENQICPPGQPLPVYSEQTGSFISADEAWKLKDASTAMWEQADGEKERLFALMTPVEQKLAKKKSAAHIPLDTVMELRRCSWSQVLTEVERTADHWKSSPNLESKRMVFIDRIGRHSESLEAWLNLLPMGDYGASICGAASTYSNTPEIIFEFLAQIPDMMESSRQYMAMYRNMGGHRLDKRSFELFRAVLEALTHVMQFFLNSRLKNLTHAWLKQGAYQEGLQRSIENVRTKVRAFRDEAQQCHAQETHESIRLLSDMNQQSKTLAPFFQRFFKLLETNLGLEQSDQQSSSPQPRISAYDMVNATHILPGTSISMNTRANADERRAEAKKAQNQSSHPNTTRKFQVIHDEYNVIKLSSRQWRRRHRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK08</accession>
    <name>A0AAD8XK08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_608799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368710.1">
        <property type="nucleotide sequence ID" value="XM_060507494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK08"/>
    <dbReference type="GeneID" id="85391393"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042124232" evidence="1">
        <location>
            <begin position="21"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="407"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="669" mass="72649" checksum="8E3700403D534820" modified="2024-05-29" version="1">MNYTFLLTTLLSSQLLTSSSLFFHSQQQNTNAIMPGRTISFHQGELALHEQLKIPRRANPTAAGLPPSYGNRIAAAPLLALGTLDAERRPWTTLWGGEAGNVARPIAEDVLGLRSWVDVVDDPVFKALWGAEGNVDGDQQQQQHLQEVIQPGRGPDGGKLVSGLAIDLTTRDRVKFGGRMVAGAVTVALDGGDRSSFSSAPSEVQIAVHVEESLGNCPKYLNKKDVIPRASLVKGRVERELPLSEEAVKVVRGADMLFLTSGYEEGGDHGGGSSSMDTNHRGGSRGFVRVARNDEGGVEIVYPEFSGNRLYQTLGNLKLNPLVGIAIPDFKTSDVLYLTGSASILVGQDAANYLPRTKLAVKITVSAAVFVQLGLPFSGTPLEPSPYNPPVRPLFSEQQHTLSSSAEKTRTATLLRREIITPTIARFVFGLEPAAQWEAGQYVTFDFAEELDVGWIHMRDDEPQSLNDDYVRTFTVSSPPGDSGGREFEITARKNGPVTNLLWRWSLRVPLEVPVLGFGGEEAFRMGRRGKQDDDGGDDVEEVFVAAGVGITPLIAQAGGVLESGVRVKVLWTVKGEDVKLVRDVVGRIPGLAGVLRVFVTGEVGETEEAMIWEFEGLEAVVERRRIRAGDVKGGGIKRRYFLCTGPEMLKVLNGWLEGEDVAFEDFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLC9</accession>
    <name>A0AAD8XLC9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="4">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_568360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HTP reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369597.1">
        <property type="nucleotide sequence ID" value="XM_060504059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLC9"/>
    <dbReference type="GeneID" id="85387958"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="13">
        <location>
            <begin position="34"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="28759" checksum="0A1F6F5AFBD3E0B8" modified="2024-05-29" version="1">MAETLQIPGPDVAWLAPRLPSESAIQSARSQGRPFVTLTFATSLDSSLSLAPGVRTRLSGSESKAMTHHLRRHHAAILVGVGTVLADDPGLNCRIDGANLDAQPRPIVLDPRGRWDFTDHNKVFEVARANNGLAPFVLVGPSAVNPERKAILEAHGGKFVILESRKTEPRFDWPSILSALHAEGLESVMIEGGGQVINSLLDPACHRLVDRVIVTIAPTWLGRGGVVVSPDRVQNTEGMPVPAARLTDVAWHQFGEDIVLSGQPSLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLG6</accession>
    <name>A0AAD8XLG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GATA zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_36680</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369638.1">
        <property type="nucleotide sequence ID" value="XM_060502615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLG6"/>
    <dbReference type="GeneID" id="85386514"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034757">
        <property type="term" value="P:negative regulation of iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000039">
        <property type="entry name" value="Siderophore transcription factor SreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="117"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="11">
        <location>
            <begin position="297"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="562"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="62445" checksum="9356D451E75D712A" modified="2024-05-29" version="1">MAMADGMSSAAQGTAKQPPSTIRTALPSRRMSPKAREGGQYAAMEQARGPSPIGRGESLEGPATLRPNSRRSPSSDTMSRSQARSPVSVSSDGSPKDVRSEPRPSPAPSTATTSSSGQTGQVCSNCGTTRTPLWRRSPQGTTICNACGLYQKARNASRPTNLKKPPHLVAAAPRTAPPKIAPAPGPGPKYLSAPAPTYVTEEQAPSGTCPGGGKCNGTGGAEGCSGCPAYNNRVSKSAHLNVQGQGGCGGGGGGGGGSSSQSQGEPMAVDDPVAPVDIAALQLQQAQNPNHTVVIACQNCGTTITPLWRRDESGHTICNACGLYYKLHGVHRPVTMKKSIIKRRKRVIPSSFGGEWTEEMLEGSETQSVAPEGSPERGTMNEDGSINLGFRRREENPATMLPDPLMRQNRQGSPLPSHDLAAYQSSSSRTSNPYPGSLNDDNRLAPITSLAAMGERQPSLSPGSFLSPSRKRSLSAEGNPSGDGGPDTSKRLSSIKSILNPTTADDSPAYHSGSDDAAEHYARSAMSPAASAPSPGSYSNAQMTPLPSPGPSSQTSNPGFRPENERVKAEKRAALIREAERMREMLAAKEKELADMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMG7</accession>
    <name>A0AAD8XMG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_603139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370178.1">
        <property type="nucleotide sequence ID" value="XM_060507210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMG7"/>
    <dbReference type="GeneID" id="85391109"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8648" checksum="4243C898EB45A7FD" modified="2024-05-29" version="1">MFYLSLITSTGTAQPLLAVLHHQCVCYHKITSEWDQTFQEVVLAKNPHVLSALRHSALSKLYRAAQLLLVLTCRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMV8</accession>
    <name>A0AAD8XMV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370425.1">
        <property type="nucleotide sequence ID" value="XM_060513458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMV8"/>
    <dbReference type="GeneID" id="85397356"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="35153" checksum="CC661A940920CECE" modified="2024-05-29" version="1">MMAVDFIRSQFKKLPYPSDDCAGRTIIVTGSNVGLGLEAARHFVRLNAAKVILAVRSTDKGEAAKTDIELTTGRRGVVEVWPLDQASFESVKEFAARADKLPRLDYAVLNASIATSKRVDAEGWESTITVNVLSTFLLGLKLLPVLRRTGKTHNVTPKIVIVASDASQMAKFHERNEEDIYKALNTNKSLTDRYNTSKLMQVILARQMAIAADASGKGRVQVTTLNPGLCATALFRNIPFPLTIVVKVGLKLLARSAEVGSRCLTASAFAGEEAHGRYMSDCVVVRFPKVMQGEEGEQMQGRVWEETVELLNGVDPGVSMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNB7</accession>
    <name>A0AAD8XNB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370600.1">
        <property type="nucleotide sequence ID" value="XM_060513418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNB7"/>
    <dbReference type="GeneID" id="85397316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="332" mass="35916" checksum="32F9F749042EA55D" modified="2024-05-29" version="1">MAFVICLFRRRSRDDYDHSLKSEIGHPNPRPDTSPTPLSGPLYAIREGIRTPLTPPPRLQQRRLLSTHGNPERPSINISVSIPGTPLGASVEKAGIFSPSLISTPTPIAANRVPPKYDRSTKPYYRVSPPPPQSTFGQGTSGGPRYSGKTSSMSSAASSRTATTVSNVSSIFPHLVPYSWPMRPPRPHEKPLLIPDLVCPGPPPARSLPPAPPGSPTSPVSFHKKLLLQQLQQQQQQQKRGGSFDSVSAAVSNGWIPPRNPARGVMLEKESRDLCELTETCAREWRERNSWGSWSIGGGGTGVGTSSVQKGGGSVNSPVLEEEDLERIGGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNJ5</accession>
    <name>A0AAD8XNJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_601566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370614.1">
        <property type="nucleotide sequence ID" value="XM_060507112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNJ5"/>
    <dbReference type="GeneID" id="85391011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="68" mass="7013" checksum="DCFC71B6D4E296CC" modified="2024-05-29" version="1" fragment="single">MRLASPQQTAPLPLPFFIHCPPGLLPARGASPGTLAVLLPQSSSQSTVATDSLFTRPSASGVAVSQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNZ3</accession>
    <name>A0AAD8XNZ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">M protein, serotype 2.1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_291806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371040.1">
        <property type="nucleotide sequence ID" value="XM_060502195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNZ3"/>
    <dbReference type="GeneID" id="85386094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38120:SF1">
        <property type="entry name" value="M PROTEIN, SEROTYPE 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="68428" checksum="A0A4786A864C26F5" modified="2024-05-29" version="1">MSAATAKKPPAAGVGRVSSTDSASTPSASPARTPTRSSTPTAASAARRAPARSGTPVSARAAATRRDSVLSNGNGNGSSEAEEAARAETLALLDDLKERLSKAEISSDQYRKQVEVLQTRLDDAIKESSKLEEKVHETEEQIETLRNEKRDAAKKMREMEAIYEAERSSMTKEKEEMSNREEEMQTIIQRLKDNLSQRNDEEGRPSRQSAATSPNVDNGSFAPPSSLNRSDSRNNSKLLLQKDKLIESLRLELAEAQIKLVESENQGGGRLQEVERLLMEARMANARLMEDNESYQLLLQEKTLNGDFSKNDFSYMGVSANQDALNALEGRSGGASLADELSEDASDAGGNDNEHARRLESELKSMKDQNKALTLYINKIIERLLQHQDFEHILDTSTEIKPAANTNKDLPAPPKEGASGASLLQRAKTMAVGPNKPKQRPMSYMPSAQPANSAHTDPETAPRIPIGNMTRSSSTRRARPMSEQFTGVNLVNQMYRGPDGPISPPLGSPRTPRTSQTFFGGNPNAAARAPSGQQAPTAGNFPGMRSETSSTSGDSNDLTGTPPSQSPPRSHHEKQTTFAGNKPRPLRLVQENNEAKQENNKRSSWMGWASGWGKKEEGAAAPGSNEAIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP95</accession>
    <name>A0AAD8XP95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IFRD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_746993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IFRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371202.1">
        <property type="nucleotide sequence ID" value="XM_060513353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP95"/>
    <dbReference type="GeneID" id="85397251"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039777">
        <property type="entry name" value="IFRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007701">
        <property type="entry name" value="Interferon-rel_develop_reg_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354:SF1">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05004">
        <property type="entry name" value="IFRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon-related developmental regulator N-terminal" evidence="3">
        <location>
            <begin position="72"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="51556" checksum="C251DB21CC85D174" modified="2024-05-29" version="1">MHDLRLKVLRESGKTVSKKAKSRPESARASMRNSPNVSPGHSQINSPAHSRAGSRYASEDESSDSDYDDGMTMSTLSNHSDTALDEATEPNWAQLLQDRIVELQDRKRTNTQRREATLMSYLHLVKHHYGGRQVSNSLQDIVTALMKNTRSGGSSLERLMSLKSLSATLLTTPSDSLFDDIYPQLEKTLEDDDDNDVKAAAIWAMAVTTMYGGGGEESASELLEYLVTIVESDGEAVGAADNGDVVTSALEAWAFVASQVDDITENVYSAIEAFVEQLDSTDVEVQASAGFNIAFIFEAARDHEEETGEPMNLQYDPKKLIALMAEASKPSVKQTARRDRRHLRKQFASIVSSLEHGKGPGYSSASRPAFNPHTGGTKADPGAGRRGDDDDGENRAFGYREKLRLGSTVVLIDSWSLMARVEATKTILGGGLPTHFNDNPTVAELLDNAETEEAAAQLYAARPNKSAKHMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPE2</accession>
    <name>A0AAD8XPE2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_646515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371144.1">
        <property type="nucleotide sequence ID" value="XM_060509976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPE2"/>
    <dbReference type="GeneID" id="85393875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="157" mass="17998" checksum="8239C2FBD3935AC7" modified="2024-05-29" version="1">MSRHWNSWVFQNPCFLTIFTPQELDQVTCMMEYLFACELGSREASVFLVLSWVASWTESPTKVQVYVSVLQMASTLARSPRFEQLSQMREDAEKDRIRRTAIRNCTTYDTGEPQVSEAHLLRRARVRVSVFVANEGRALEDSDGLSRLQADRGEGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPE3</accession>
    <name>A0AAD8XPE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Insulin-induced protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_598484</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371280.1">
        <property type="nucleotide sequence ID" value="XM_060506953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPE3"/>
    <dbReference type="GeneID" id="85390852"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="384" mass="41999" checksum="772CA3A03D1283F8" modified="2024-05-29" version="1">MSDDGPRLIRPIPRRPFELNHIAPTPPEDDSSSPSPNPEFDLSRLHNGQTTSSESGSIPRAQSVLNMTASTLFGIYSPTTYGRDSRDEPDTPWGTGAQTPIKRANVDDTTFELMKDRSNLLRRRSSYRSGAKTPPPSTATTALFNLSRIALLFVIGMGYGLMVTRLQNEHRFSSFQVDSMMKPGYNWQYLTLWGLSGVGLGGLLPWFDGVWEDAFGKEEVVLEETNGSPSSPEDVSPVKDWAVVVRSIGAFVGIVFAIRKLPWASTLQVSLTLALVNPFLWYLIDRSKPGFLLSAAVGLAGSAVLLGINPDVMPTPSSLTYRNESERAYSEPITLGGLASQETIETGIWMLSVLFCSCVCFGNIGRRLALNKSASARGRWAGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPV0</accession>
    <name>A0AAD8XPV0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_160878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371532.1">
        <property type="nucleotide sequence ID" value="XM_060501396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPV0"/>
    <dbReference type="GeneID" id="85385295"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="28326" checksum="24068A3CE039BDB8" modified="2024-05-29" version="1">MAAAVAEHPRFFPSHHDALSHDDFETASIRSAAPSYFSDAPSYHSIAPHPEPIPPYSPPANNNNVNRTATGSTQHPTSLLPAVPAPSRSGNSTPQPHRTTGLPPIPPAPPSAAPRLDQFRIPTWSTVHTNPTLNNVARRRMNQGADPVAHLRRFMSERMAEEEAAQRARDFRPLEDPYLVGEEAAASARRERLARESGEDILWDEDRRWNRFLAAQMQTWEDRDRSSWRNLRQPPPAQRKKLTRRLAGRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ27</accession>
    <name>A0AAD8XQ27_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371386.1">
        <property type="nucleotide sequence ID" value="XM_060503715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ27"/>
    <dbReference type="GeneID" id="85387614"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990861">
        <property type="term" value="C:Ubp3-Bre5 deubiquitination complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000003">
        <property type="entry name" value="Nuclear transport factor 2 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="43"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="307"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="542" mass="56673" checksum="BAF3A105F9DD4BF6" modified="2024-05-29" version="1">MATNGNYTHPDQFKGAVEPTSSGPTSTNDAVSAGNSNLSKDEVGWYFVEQYYTTLSKNPDKLHLFYGKRSQFVYGMEAEVANVSVGRQTIQERIKSLDFQNSKVRITNVDSQASFDNIVIQVIGESSIKSAEPKKFVQTFVLAPQPSGYFVVNDILRYINDEEEEEAAPEAEAAPEEQAAPEEVAEVSAQAEAEEPKVEQTPEEATGPAIDVDEVEKKLEEVSAAPQDVASNNGDAVPAVPEPAKAAETKVEEPAADPEAAVKEVAEEDATEPEKPADPSPTPVAPTKAPAAEPEKPKPAPAPVPMKPMSWASRAAAAVGPKPVVPLPKTATPPAGQAKAPAPAAPAAAPAKEAAPATDAPAKEAQAQAAKEDSPAAEWQSVGADSKRQNRPQSISQAPTENYGTLGYVKYVTDKVKAEDLKGALAAHGELTYFDINRQKNCAFVEFATVAGYQAAAAANPHTVNGENIIVEPRRPKANAYGGSSYSSNTPRGNATGGGRGRGGFEGGNRSGSQGGGRGNFTGGQARGRGSVRGRGASQATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQC7</accession>
    <name>A0AAD8XQC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_645743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371820.1">
        <property type="nucleotide sequence ID" value="XM_060509881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQC7"/>
    <dbReference type="GeneID" id="85393780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="59449" checksum="35965EE2B11283B7" modified="2024-05-29" version="1">MADSARSSDKNPRSPLKSKVVRSQKISPPNDSRPPPPGVPDDLEDFSDRDIEQHRRVPSAPGGPIIPRSHTPGHLASKSQDRRRKPSELSIRQRSQSASQAQASQQSRTTPTSANTPRPPPPSFRPSNTASDATTLNSNDGSESTGGHGSDRDGRRPIAMRSTSAIAAKPSSLPLSSSSTRQLSTTVSSRSAPKGQHIPFPPLQDPKTAPDVPPAPSSGMYWSRAPVSGAPHTSLRAHTTTLVGSNIFVFGGCDSRACFNELYVFDADAFYWSVPHVTGEIPVPLRAMTCTAVGKKLVIFGGGDGPAYYNDIYVLDTTNFRWHRPKIIGDRVPSKRRAHTACLYKNGIYIFGGGDGVRALNDVWRLDVSDMNKMSWKLVSGPERAPPPGVRETRPKPRGYHTANMVGSKLIIFGGSDGGECFNDVWVYDVDAHIWKAVSIPQTYRRLSHTATLVGSYLFIVGGHDGNEYSNDVLLLNLVTMTWDRRRVYGLPPSGRGYHGTVLYDSRLFIIGGFDGSEVFSDVWMLELAVHAYYSQISHFTIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQY9</accession>
    <name>A0AAD8XQY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_564025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371891.1">
        <property type="nucleotide sequence ID" value="XM_060503599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQY9"/>
    <dbReference type="GeneID" id="85387498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="589" mass="65957" checksum="56CFD2CBE279FF2B" modified="2024-05-29" version="1">MPAHRQQDLPVESSWRLVEGGENDSFDTSILNDLEEDDGFLTEPSQLPSQSFSIGGSQESHHSVQDFMNKADDERVILRSPFQPTVRRDPNRSPEPEFIMPSMRFSSTSGTGTSPQHSSGHSSRTIRPSDVSYQQQDVRRRAIRQASTGSPTSARRGDPRRVRGYYNEPAEPKTVTERLSESLPGAAFNILAWIFNVIGMALGYIQKPLALCLAVWLFFGASIMLQNMVTKSITTSLSPLCRIPGAAYLDLPFCPSFTTSPDGGKESGSESANVEFDDLMNVQSQFEQVLERSADGVSLPMEMKRSESSIRDLRTMVRYSELPQRDELVYEFNEYIDTARLTASDLQKFNVHVGSAVDSVISINRWTSRYLDTLSASETTDVGLVSQWSSWLFYPFTPTVTPFSERTLLDKYIEHTALVSDRISSLIVEAQGVLLLLTKAEENLNQIYEIVTRSSNSVKSRRDEVLWTLWTLVGANNKRLHNLNAQLSLLRQVDRQRVTAVAQISALIVDLEKIQAGLGDLRDRVAAPELVRDSTIAIPLTVHIETIDRGVERLEDARQRIRAAENDRIREALARGGAKEDDKLIEGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0J3</accession>
    <name>A0AAD9D0J3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_567240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370068.1">
        <property type="nucleotide sequence ID" value="XM_060503939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0J3"/>
    <dbReference type="GeneID" id="85387838"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF4">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_7G04540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="32402" checksum="2D9991B8C3E7518E" modified="2024-05-29" version="1">MSTGQKTSGPEGNKLFTRNHLFDLTGKVALVTGGGTGIGLMATQALASNGAKVYITSRNQSKLDNTVQTYGQNVSGSIIPIVADVTKKSDIDKLYKEIESKESALDILVNNAGVSSAPLEVESDSAHDMKASLFDAESADFEDWTETYRTNVAAVFYVAASFLPLLQKSTDKQHGWSGTVINISSISGMIKKSQHHFSYNASKAATIHVNRMLAEEIASNGLKIRVNSIAPGVFPSEMTTKEPSDEEQKSEIPKEKYADKVIAGRPGKDEDMASTVLFFACNQYLNGQTLAVDGGYTLAAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D298</accession>
    <name>A0AAD9D298_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exosome component EXOSC1/CSL4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_602602</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370446.1">
        <property type="nucleotide sequence ID" value="XM_060507183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D298"/>
    <dbReference type="GeneID" id="85391082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="5">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Exosome complex component CSL4 C-terminal" evidence="4">
        <location>
            <begin position="118"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="165" mass="17782" checksum="097541CB598D9118" modified="2024-05-29" version="1">MATVETPQTAVPGKVLGPITRFAAGPGTHVYNGNVVASLLGDVTVTASTKAQAGLTKRLNRITPLSPEELATISVARKGASKKREMLPDVGNMVLCRVVRLMPKQAIVTIQQVGDTVLQTEWQGVIRSQDVRATEKDKVKIYESFKPGDVVRAQVVSDSLQDIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D386</accession>
    <name>A0AAD9D386_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_565111</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Involved in the replication of mitochondrial DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371465.1">
        <property type="nucleotide sequence ID" value="XM_060503712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D386"/>
    <dbReference type="GeneID" id="85387611"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005760">
        <property type="term" value="C:gamma DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08641">
        <property type="entry name" value="DNA_pol_gammaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000035">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.390:FF:000003">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.390:FF:000006">
        <property type="entry name" value="DNA polymerase gamma, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041336">
        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047580">
        <property type="entry name" value="POLG_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="16">
        <location>
            <begin position="706"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1134"/>
            <end position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00057053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1731410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1153" mass="130163" checksum="E09AE52E78E0A0DE" modified="2024-05-29" version="1">MVEIANHVLRSSTASFVRLARHRHHASRRLAWRSYVRWQSAIAADASKTNDIAESQQSLALPSQARFNDIGVQHLSAHVYKQLFPDGNPPPPSELVELSKDHLRRHDLLGKNTDNSDPIAFDLPELQGRTLDEHFYKLAVDSAEPYLSFAKQFARASAPPKPRKWVRRSGWTKYYPDGRTEVVDAPDESMICFDTEVMWKESSFAVMACASSPTAWYAWLSPWLLGESESDRHLIPLGDPTKERIIVGHNVGYDRARILEEYDVKQTGNSFLDTMSLHVAVNGMCSQQRPTWMKHKKSRELRDKIANETDDVQLAELLGNSALRQEEEELWVERSSVNSLRDVAKFHLDVTIDKAVRDEFGSLDRDGVLSKLDNLLDYCAADVAITHRVYQIVFPNFLDTCPHPVSFAALRHLSSVILPVNKTWDAYIHNAEATYRELSDAVQERLIGLTEQALAIKDDPEKWGNDPWLKQLDWSGQEIKMVKGKKKNDPPRPAARQKKPGMPKWYKDLFPKNDAPIAISVRTRIAPILLRLSWDNHPLFWSDKYGWTFKVAFDEAEAYAQKQMVECDFSDSDTDAALLKEEGIFFKLPHKDGPTARCVNPMAKSYLSYFEKGTLSSEYAYAKEALEMNASCSYWISARDRIRSQMVVYEDDLSVNDEKASSKREKSAEEVQGYILPQIIPMGTITRRAVENTWLTASNAKKNRVGSELKSMVKAPPGYCFVGADVDSEELWIASLVGDATFKLHGGNAIGFMTLEGTKAAGTDLHSRTAGILGITRNDAKVFNYGRIYGAGLKFAGQLLRQFNPNLSEQETNATASKLYATTKGTKTNRSVLSKRPFWRGGTESFLFNKLEEFAAQERPRTFVLGAGITEALMRRFINQNGYLTSRINWAVQSSGVDYLHLLIVSMDYLTRRFNIDARLAITVHDEIRYLVKNHDKYRAAMALQVANVWTRAMFSQQVGIHDLPQSVAYFSAIDIDHVLRKEVDMDCITPSHKTPIPHGESLDITTLLSKGAEARLDPAIVPDPSHAPKFDGIEYTPRTPVMETLEDKATADTFFLKAQIASSEAELSQVLKDRRTALKAQEEKMMTPKPPRAKKERSVLPYHSDAKLVPTMTVSDAIGNRFSRYDGKSKWTTWQKEKGVGRSGPSSSYNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U641</accession>
    <name>A0AAD8U641_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_657704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000207">
        <property type="protein sequence ID" value="KAK1707555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358092.1">
        <property type="nucleotide sequence ID" value="XM_060510983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U641"/>
    <dbReference type="GeneID" id="85394882"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="24904" checksum="DCBE52267441AE4D" modified="2024-05-29" version="1">MMLLRPVHEVVPESFEELLMCPKPPSLSPDKTSDVSACLPVGPAEDSGPLREEQETGVVPPSPQRPRHVRLDLGQPLLRVGGRTIPLAQRLGLDWHRPRLEAGIKKGGLDAYNSLALSLGRSGEASEVEYPTVLCRYLTLRKGLPLSVPYVLYIPFRMSGTSATYLEEDKHVKIRRCGLQLPTSLAVANAISKSPTANKPPRKLASLWFEDGVCISECTCHDPGPALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U810</accession>
    <name>A0AAD8U810_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flavonoid 3',5'-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_639433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359157.1">
        <property type="nucleotide sequence ID" value="XM_060509425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U810"/>
    <dbReference type="GeneID" id="85393324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF85">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1711604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="570" mass="65124" checksum="8E1135413572677C" modified="2024-05-29" version="1">MSPLRKSSKTNFQASTWTGPVLVAEDDQQLWDFGRGCNASSRSSGKHGAKWYSLNYNLFTIAFKMALLSLGNILLLSAAYMVWKILYQIVYYRFYHPLVKFPGPFWGSVTRLWITYHNVREDECRVNQELHKKYGPVIRITPTMLLVSDATKLPEIYHRNANKSQHYITGSFGKTESLFNMQDHVVHARFRKIAAAPYSFSNIRKMEPLLDKHIERWISRLDAFASSGTKMDFAPWAVYLAYDIVSEVGFGQPFGFIEQGKDVEGLIQGFHDGLVPFGILARCYPFTNWVKSTFMGKYLVASPEQDSGIGTLMRFRDGLILQRFKDIEKGTTEGRIDLLQTFIEARDEDGNPLDLDYIKAEILLVLLAGADTTGTAFQAFMMHIMTHPEVYDRLMAEIDEQTRAGNLSEMPQYAEVLENCPFYVACIREAMRLNPSAPNIFPRLAGKGGMELYGKHVPEGAEVTCNPWLVHRDENIFGPGASDYRPERWLESEEKTKEMLKYNMGFGYGARVCLGRDLAMMELFKGPLQFFRTFKPVILSKRDPGKYVVKGGVSFFKDMWITIERRPKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8A0</accession>
    <name>A0AAD8U8A0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_105624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359307.1">
        <property type="nucleotide sequence ID" value="XM_060501053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8A0"/>
    <dbReference type="GeneID" id="85384953"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="475" mass="54626" checksum="4B67786079C6BC68" modified="2024-05-29" version="1">MALSVLVAAMSHLIRSNRSYREIAARRKENCLETNPFHEAQAESQNSSSAPHTTANACEESLQALDSNAKVAQSIDGLKKDPAQPPVLSRFLRWMKALPSHPKKKKSDLGPCLDHALPLNLHLAIAKHLTMAERVALALTSKRMLAIMSNEQFWLNRGSSERLDLLKLLERDAINTRREILCLPCQIFHDPVSSVPPVDHDSSWAPTESDRPCIKAVSEDHHQRLSSPYLPHDFHFNMIKAFLHSKRHKTGFFESILLEKSTIWGYCYKREEANVQQGFECRVSSEGDLLVKTTTRLFACRDPNQTKDKIQFAVRILKRAELTTCCKHVDWIETYPFIFDYDGLLTDESKLHAYRASKGYGYDPAKKIRDIWDPAVMPRYGPKNHIPIMHCESCYTNYEYEWKDTKDGSRIVFLISYKNLGRGVDTNDPKWSSHFDDHIPDAKAEPRNSHYDGFTRWPHYAWQETADEAPWDPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9M5</accession>
    <name>A0AAD8U9M5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_591860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000180">
        <property type="protein sequence ID" value="KAK1709707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358618.1">
        <property type="nucleotide sequence ID" value="XM_060506484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9M5"/>
    <dbReference type="GeneID" id="85390383"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050287">
        <property type="entry name" value="MTA/SAH_deaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794:SF11">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43794">
        <property type="entry name" value="AMINOHYDROLASE SSNA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="67"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="305"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="54865" checksum="FE8D410CCFE0A509" modified="2024-05-29" version="1">MTTSQATPPATGSILLKGGTLLFHNERDDVTPLRNTDILVQGNRIAKIGKAIAPPAGAQLVDCSGKIISPGFVDTHHHLWQTQLKGCHADQSIFDYIPSGYWQSHVYSPKDMFWGQLGGALEAIDAGTTFVLDHAHGNQTNDHATQALSATIASGIRSIFAYSQAPYFTKWDSKSCELSMDIMPDSSMAHIFELAKAQPYGNGRVQIGFGFDYWFLPKEAIVGIFNGLRHAGIKLFTSHYAKNPTFANPLIHTLDAYGLIKSPSDILLSHATGLDASEKAKLAETQVAVSSTPDTEAQMGFGWPLAFSSGINYTIGVDCHTNNTSSILSLARSALQMARQREALAETNEDGAPQKLNLQPAGSTQDAFNAATIRGARAVLLGDEIGSLQEGKLADLVLFDAAGSVTMSCVADSDPLTAVVRHSDIRDVEAVLIDGVWRKQGGKFCPVTVAETGSTLQWAEIRDKLLESQREIQHRQKNLNMEKAKEALVAMYRINTSNLIEKPKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9P3</accession>
    <name>A0AAD8U9P3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_644481</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000258">
        <property type="protein sequence ID" value="KAK1704786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357485.1">
        <property type="nucleotide sequence ID" value="XM_060509757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9P3"/>
    <dbReference type="GeneID" id="85393656"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF13">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1704786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="15916" checksum="A44205C08CED628B" modified="2024-05-29" version="1">MQDDLHMSDTVWSAGISLFYVGYIISQVPANVIIAKGKPRILLPCCMLGWSITTICMPAVTAGWGFLLCRFVVGLTEGPFVPAVSLLTSSWYTKHESPLRMGIWHAGNTISQAVSGLLAAGVLRNMNDVAGLSAWQWFLLLEGQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA68</accession>
    <name>A0AAD8UA68_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_643883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000232">
        <property type="protein sequence ID" value="KAK1706106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357754.1">
        <property type="nucleotide sequence ID" value="XM_060509702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA68"/>
    <dbReference type="GeneID" id="85393601"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="18182" checksum="89689251C47041C9" modified="2024-05-29" version="1">MGVSENRIPGGKLRSNRIMRCSVREWDIPTAAADLEELSSWITEEKRLLSSIRHGSDGSVYRFSAAASSIRYLESIPAAMRAQLRKIVLVEDYRSVTHPESHARGLIPFCRENPLLQFERCVNLWRDLFQVDKRWHTPHQQCEHQNRAVRSRVAAGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAU6</accession>
    <name>A0AAD8UAU6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_642429</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000201">
        <property type="protein sequence ID" value="KAK1707975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358191.1">
        <property type="nucleotide sequence ID" value="XM_060509613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAU6"/>
    <dbReference type="GeneID" id="85393512"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000033">
        <property type="entry name" value="NUAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="81"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="15">
        <location>
            <begin position="159"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="14">
        <location>
            <begin position="298"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1707975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="791" mass="86383" checksum="B8A2EAA55686C00B" modified="2024-05-29" version="1">MPQARTPPNPHGPGQKSSSLPTSTIEYQSASHPNALPRFVRVSIRQGDTMLRHSLARSAWRTGKQAANASRTFATTARRNAEVELTVDGKKVSVEAGSALIQACEKAGVTIPRYCYHEKLAIAGNCRMCLVEVERAPKPVASCAWPVQPGMVVKTNSPITHKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMRYGGDRGRFHEIGGKRAVEDKNIGPLIKTSMNRCIHCTRCVRFSNDIAGAPEMGSFGRGNDIQIGTYLEKNLDSELSGNVIDLCPVGALTSKPYAFRARPWELKHSESIDVLDGLGSNIRVDSRGLEVMRILPRLNDDVNEEWINDKTRFACDGLKTQRLTMPLIRREGKFEPADWEQALMEVANAYHHIQPKGNEFKVIAGELTEVESLVAMKDLANKLGSENLALDMPNGSKPVAHGVDVRSNYLFNSRIYGIEEADAILIVGSNPRHEAAVLNARIRKQWLRSDLEIGVVGETWESTFEFEHLGLDHAALKQALAGPFGKKLQAAKRPMIVVGSGVTDHVDAKAFYETIGAFVDKNAANFITPEWNGYNVLQRAASRAGAFEVGFTTPSTEVAETAPKFVWLLGADEISEKDIPKNAFVVYQGHHGDRGAQIADVVLPGAAYTEKAGTYINTEGRVQMTRAATSLPGASRTDWKIARAISEFLGAPLPYNDVAQLRDRMAEISPALAAYDVVEPVALQQLSKVQLVDQNKGSKASGTPLKKVIENFYFTDVISRSSPTMARCSAAKASGSPKTNFMAPGMEEDRPMGQIAYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBN9</accession>
    <name>A0AAD8UBN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/Exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_657075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000171">
        <property type="protein sequence ID" value="KAK1710344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358814.1">
        <property type="nucleotide sequence ID" value="XM_060510933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBN9"/>
    <dbReference type="GeneID" id="85394832"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000036">
        <property type="entry name" value="Inositol polyphosphate phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF240">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE 5-PHOSPHATASE C9G1.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="784"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1184" mass="131161" checksum="400982F085FF5343" modified="2024-05-29" version="1">MNKNGESAAAPGPSPPRTISPAPKPEFLRDAKASSESLQSLPVPPRPRERPSISAPSLPPPLHEPVPRSPGRSLGVPPTLKPEPIKAPSVLVEPPQSPPKNSISRFSIAEAPAFLNAADSGSSTPTTPTTSRAFKIPSRPHTPSLDPRRSPRLSASQPPSPPPPRRSGEIRRDNKPAVPPPINRAEKPSMRDQPKAPYYADHQIGAAEFRGKLREETSPFSSPPGSPDSIHEPAPPTLPTRPKALATLTEPPPPQRGRPIDVGFAPPPVHHSIMTKRNQREQETNGFIRGQITPQITGDRPSVPALPARPQTVAEPPPRPPVTMKPPPRPPRAGGINTHVASHSVSHSVDFQPPPKRIVSTPTTTHLPPPSRLPGRANTVTDRTSPRPPPPQPPQPVQHVQHVQPAQPPPPPEPTVSLIPSSNTSKVEINGNIPNFPDPANVNRRPPYIKHGMHEIQTKYDPRTFDVCGDLICTTGHLTRVWNLRDGELLMSFAHGEGIKATTVAFKPGLNVDEEGKRLWIGNNFGELMEADIATQSVVANKPGAHGRHEVVKIYRHFNEMWSLDENGGLLVWAADEETGTPNLTNNAHQAFRLPKGHSFSMVVGDELWHATGKEIRVFAPSSDGQTQFQVLVRALAQDTAGEVTSGTQVRSQPNKLFFGHADGKVSIYNTQDFSCLGLVNLSSWKINSLAGVGDHLWAGFNTGKIGVYDMEPTPWAQKKDWQAHEKNPVVKLVSDASSCYRLDRHQVISLGADNMLRVWDGLLQDDWHEAEMKAMDTQYCEFQDLKVLCMTWNAGASTPHSLRYAQEDAEFIKSLLTSNSSPDILIFGFQELVDLEDKTATAKIKLTPEERFLKVKKKEGSDQERMSHQYRDWRDFLLKSLDDYMPPDCLYHLLHTATLVGLFTCIFVKSTLRDRIQNLSAAEVKRGMGGLHGNKGAIVVRFMVDDSSMCFINCHLAAGQSQANSRHNDIAAILEAQILPPERDPSARLDSYVGGGDGTMILDHELCLLNGDLNYRIDTMSRDTVVIAVKQNNLAKLLERDQLLVARRRNPAFKLRAFEEMPITFAPTYKYDVGTDNYDTSEKKRSPAWCDRLLYRGGGRIKQVDYKRHEVRVSDHRPVTGRFKFTVKKIQPKARAMAWMDCQQRFEDLKWTEVDNDKMAYLTNVIGYDEATARSIIRPESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBW2</accession>
    <name>A0AAD8UBW2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Necrosis inducing protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_723966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358935.1">
        <property type="nucleotide sequence ID" value="XM_060512612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBW2"/>
    <dbReference type="GeneID" id="85396510"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041902468" evidence="2">
        <location>
            <begin position="19"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="326" mass="35084" checksum="30071D83AE40165C" modified="2024-05-29" version="1">MRHSFFSSLLGLATLTAGAVLSPREKDVSLNNQWKNHDRIAAFQQQTADGTPGDIELRFKPWLNDGSGCFPYAAVDKDGFHGRGLKPTGKSGGDCRDSAKGQIYSRVGTSNGRPAVLYSWYLPKIQTKTEKHRHWYLTTVVWLHTETCNAAAGNYDIAGISYSTGTETYDKGLTSSTIFASGDSGTGATNTHAIVGYDGQVNVFPSANNAQYGLSPPLISWDRLSPAATSQFNAFRYEHARCPFTDANIQASLDAAYNADFYANLPAEPDANCGIIATSTTPSTPEASSTGVSSDPNTDPVEDGPEIPISSFPADPTYTPTPYKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH5</accession>
    <name>A0AAD8UCH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_639823</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359046.1">
        <property type="nucleotide sequence ID" value="XM_060509455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH5"/>
    <dbReference type="GeneID" id="85393354"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="391"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="133"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1711243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="787" mass="88480" checksum="584B87C9A8FD43E1" modified="2024-05-29" version="1">MTRDRHASRASFACVRCKKDKRRCDISQILSSGDRLDRSCTSCRNKNEKCEVRYGEDKRSQRQPNETKALQRRMQALEEFVKNVSKNPELPATRHKADNDPDCLMEQARRTVDNYQDARIRAFPSPASSSSPGTQNMTISISPPEGGQNNWAVTSQQEFHPASHSRSVSFSGQNRPKADDITHNGIRSISFSGPSRPDFDCVSEGFPPVMEEIGTPDSMHDFDQFLGSATLFPYSENQSRSRSPRGEGSSFEDDTSKQPRGALECFPEPEPIVSHLLDLFWKWQSSHLLVIDRALFLRHREIWDDSEGHRGDRNYYTPCLLYAIMALASMISLDKGVVRYSTSPGSVAGETFAKRARSMFDLEMDHPTISTVQAALILGSRYGAMKDNSLGWMYSGIAFRMASKLGLHLDCSKAVASGKMIQEMADLRRRVFWGCHIEDNLFSAYCGRPNSFMEWDITIPIPERHFKCVGKDETESTSSLLHHTSTLSVLCSKILISIHRQRRHSSTSEIRLKASQLHRALWQWHHDLPKSLTWSSDSNILAQPHVFILQMNFYFALILLHRPFLRFSSKCLDVDIMSSSALDSTHACATAAANITKLATTYRRSFNMRQMPPSIVHFIFIAGSIHLLNLRAGQPGNHEVLLQSSTEALSELGKSYPVAQKASTELESLIEKWRSAKEAEKRAAETSRAAQEVENSMSSGCAIRPGVSGFLDIDFSPLEELGEFMDLKKGQQPATKSMFDMPADIGFHEQLSLDQNGNDCMFLGQDWLQDGTGFESMDGSGCPWMYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCM2</accession>
    <name>A0AAD8UCM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_757987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358325.1">
        <property type="nucleotide sequence ID" value="XM_060514968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCM2"/>
    <dbReference type="GeneID" id="85398866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="407" mass="44681" checksum="8AB95FB0ADF1CDE5" modified="2024-05-29" version="1">MMPARPLVRSTLPRATRAVRAPRQQLRFQSTTTSSSTGGSSSHFGAGVAGGLAGAGIFYALYSFTPAGRAASKVNKAAKEAEKKYTAAAQKLQENTPSTDEAIDYIKQFAYSYVGWIPGGRSYVDSAFNDFETVRKNHKEEADKIVDDAYKQFQEVAKAGLSLEAVHKAYEVLADITQKLASLGGDAIGDIVDNHPQLKEKLGGNIDQLKDLGDKYGPEAKKQVDETWKQVKDVLAGGFTAGNFDKVRKLIEEKIQQVQKLGDEAWKKALEEAKPYLDKNPKVKELIEKNADALKKGNAKELFEKAKKATESGDLGGLESYVTDAVDKAKSKGSQVGESFGLDQYFKMIPDGDKIIPKLKQLREVADKHKEEGEKLFKETIEEVKKVLEAKSKKAEEIAEKAKKDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCQ2</accession>
    <name>A0AAD8UCQ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_153931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358370.1">
        <property type="nucleotide sequence ID" value="XM_060501342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCQ2"/>
    <dbReference type="GeneID" id="85385241"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF177">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="74"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1708688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="583" mass="62174" checksum="51A8894473A8C98E" modified="2024-05-29" version="1">MATATPENQPRLQPSVELTGSYESKTEETLGHSHDAAPGLTAPVDSEKGTGSADGDDDKAEEGDYATGLKLFILMTSLLLCQFLVALDMSIIATAIPKITREFQSLDQVGWYGSGFLLTLAGFVSLWGKAFKHASIKWVFLSAVVVFELGSLICGVAQNSTTLIVGRAIQGFGGAGMTSGVYLIVSVSVVQKLVPAFLGLLSGIFSVASVVGPLLGGAFTDRLSWRWCFYINLIVGAPSILFLAFFYKPPAHHKIEPIGWKDFIYTLDLPGVAVVLGGLTCFILAIEYGGVSKAWNSGTVIGLLVAFFVLVILFIVLEWYQGDRALLVGRLMKRRTIAACAVFVSMINFSFFPLAYNLPIYFQAVNGVSPLQSGIRLLPTILPMTLFSLFSAPGIVLVGWYQPWLMTGASLAAIGAGLIYMLDIDSTSAQWIGFQFVAGVGTGLAMQPPVIIANAITPKQDNSMAMSDVLFFQFIGGTFGIGMAQAIFNNGLISSLPELAPIVSPAEVLSIGAYDLKNVLSGDALTGVLRAYMRGLHNAWAMSIAGAAVAVFLPLLGAYMKLPKTPPKSWDDKPTTGKADARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD22</accession>
    <name>A0AAD8UD22_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_638929</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359331.1">
        <property type="nucleotide sequence ID" value="XM_060509392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD22"/>
    <dbReference type="GeneID" id="85393291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="96"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1712213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="40109" checksum="B7AE9BE441FDD23F" modified="2024-05-29" version="1">MEFHNKPQTGESFVYHERNDRSLLMLYLQVVIKSFRPRLASPSKLPPNAERLTPPKNARKCHIEERVLEELWLYDITRESDGSYDREPGPPRRRRILYFAGGGWQMPPSKNHWTFCMELVRRLDNTAVTIISVPLAPKHPVSVAFPRIQRAYSSLLNESHDAGERVIVAGDSSGGNIALSLVAWTLKHPKSEVLNPPVAVMAISPTVDLRHELPQIRVVEKSDALHTFESIKATAEAWCPEEATTESSKISQQNRGDSHGCSDWGLDDPRVSPIHADLGVFVQHNVHIYGVTGSYDVLAPEAVAFRNKCREHGVSGEWLSWERQMHCFPLMFKYGLKEGKEGTDWIIRVLDKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDG3</accession>
    <name>A0AAD8UDG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_24758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360992.1">
        <property type="nucleotide sequence ID" value="XM_060501913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDG3"/>
    <dbReference type="GeneID" id="85385812"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1717505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="22856" checksum="69A76514882C63F6" modified="2024-05-29" version="1">MSFRSLIPTGPKATWLMFFFPQESARCCRRVDCDITNSRRPAASRIVSEPIVSLIHCPTLCTCCIQKCRQTYVGYATPRYEPSGVCQLQMPRDGAALGDFRAIHICKTLGDQSDHGGFSSNCFHPRIVGSWEGRGELTVGACTQPPQRVPGGSWSLGAVCCSIFATSTALALHAGRLRTHCRSGQLCKHGIPRELIRPFLLLACLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDX7</accession>
    <name>A0AAD8UDX7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methionine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_629985</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362176.1">
        <property type="nucleotide sequence ID" value="XM_060508790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDX7"/>
    <dbReference type="GeneID" id="85392689"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000031">
        <property type="entry name" value="Putative Methionyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="entry name" value="Methionyl-tRNA synthetase, Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="Methionyl-tRNA synthetase (MetRS), Zn-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="15">
        <location>
            <begin position="15"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="16">
        <location>
            <begin position="462"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="614"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1721380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="75130" checksum="96B8793C4932DBFE" modified="2024-05-29" version="1">MAPNPILPVKGKNNVLITSALPYVNNVPHLGNIIGSVLSADVFARYSRARGNPTIYICGSDEYGTATETKALEEGVTPSELCAKYHALHKGIYDYFDISFDIFGRTPTAQQTEIVQDIFTKLWKNGYIEERETVQPFCPVEAHQSFLADRFVEGVCSICAYDGARGDQCDKCGNLLDPLEPEPEANASADDDVAAKPTGFLIKPRCKLDGATPEKRKTKHLFLRLDALKDDLVKWFKESSKKGAWSNNAEQITQAWIDKGLKPRGITRDLKWGVPIPTHEVGEDYARKVFYVWFDACIGYVSITKNYTDGDNLEGKNWEQWWKNPDDVKLYQFMGKDNVQFHTIIFPGSQLGTGENWTKLHKISTTEYLNYEGGKFSKSRGVGVFGNQVQQTGVPVDVWRYYLLSRRPETSDSEFMWQEMVDGNNNELLKNLGNFCQRVNKFCQAKTEGAVPDYTKYTDDYLKKHIDEVNTLLKEYINNMEATKMRAGLQTIMSISALGNKLLQDNKLDNRLLTEEPDRCAAVVGLALNQIDLLASLVAPYLPNTSTAILKQLGVEPKPFIPDTWVTDAIKPGHRLGTPEHLFTQIAASKIEEWKDAFGGEEVRKQKEEAAAKAAAKKAAKDADKARKKAKKEAEKAKAAGAGASVESTEKKAEADPAIEAVTEAISKTDVHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEB6</accession>
    <name>A0AAD8UEB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_723244</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360003.1">
        <property type="nucleotide sequence ID" value="XM_060512542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEB6"/>
    <dbReference type="GeneID" id="85396440"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1714541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="193" mass="20471" checksum="857726250F2053D5" modified="2024-05-29" version="1">MAPKLSEEEIDDLIYFSRAGELADLEETLKSLSEREGASVGEIITAAKDDGKSTCLHMAAGNGHLDIVKALITAFDSRPADEKKAYVDAGNEFGNTGLHWACLGGHLEAVKYLISHGASPAVANDKDQIPLDSALFNDKREVADWFLAQSEKMEGGNQEEGLSGAASGIEIEDDGAVEEDKGKDKAGESSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEC9</accession>
    <name>A0AAD8UEC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_706195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361423.1">
        <property type="nucleotide sequence ID" value="XM_060511525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEC9"/>
    <dbReference type="GeneID" id="85395423"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055080">
        <property type="entry name" value="Gal80p-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF1">
        <property type="entry name" value="GALACTOSE_LACTOSE METABOLISM REGULATORY PROTEIN GAL80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22685">
        <property type="entry name" value="Gal80p_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="16"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Gal80p-like C-terminal" evidence="2">
        <location>
            <begin position="145"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="40514" checksum="35FA1EBE3B1D5734" modified="2024-05-29" version="1">MAPIRVGIIGLSAKEAVMGPGAWASIAILPSFKNSPHYEIVALCNSSAEAARRSIEMHKLPSTTKAYGDVEQLASDPDVDLVVVSVVVTKHLAVTLPALANKKQVFVEWPLGASAQEAEQLTQLAKSGGLKTIVGLQGRSDALTLKLREIVQSGEIGEIKHTSVVGTLPYFPPNFWVEGAEYYLDIKTGGNAFHIGFGHFLDSFTNVVGDFDLSSLSSVLKSDVDSVPLYKADRSNVIDPAYPKSSPDHILVQGLLQNGALASIACRTTPVTVGEVGARWIISGTKGEIEAVWDGGQWQIHSPRKQLVYKLVGGEEQKVTLETGKLPGGVEVSAAGLNTVLIFDAFAKGDTSRYADFETALKNHVLLDTILKKSGYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEN2</accession>
    <name>A0AAD8UEN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phenylacetaldoxime dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_582188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362862.1">
        <property type="nucleotide sequence ID" value="XM_060505529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEN2"/>
    <dbReference type="GeneID" id="85389428"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025702">
        <property type="entry name" value="OXD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13816">
        <property type="entry name" value="Dehydratase_hem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="40890" checksum="EA3B73E81BD90961" modified="2024-05-29" version="1">MSSDMRTYPLRRPEGHRPPVPRWQLTLCKDVQKVFTAYIGIQPHRGASDRSTVVKQAVQAVEAWLSTDTEDRPLSTESFNHLDGDDAPNTYVWVCYWDDPEKGEASLQKLDIASVYAKLAPEHRMLVGLWRESFTTPISRLETNYSGLDYLPGLARLPKTGTKEHQLSAYWGAARDRIPASAHDLFEEDGDAKTAKPEDIPVGLGQHLTGTNYDNIVHIRSGQFWENCCLEEALSYETELEPTLKAGLGYLWENREKGGAMGLRFLGNRDADGHTKKETCGAGFFMNLSSLEEWSKKHRSHLAIYIGAIKHAKTWGESRKFRTWHEVSVLKRGEATFEYLNCSPVTGVMRFISLPRTQELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEV1</accession>
    <name>A0AAD8UEV1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutathione-dependent formaldehyde-activating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_722871</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360480.1">
        <property type="nucleotide sequence ID" value="XM_060512514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEV1"/>
    <dbReference type="GeneID" id="85396412"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF3">
        <property type="entry name" value="CENP-V_GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="18855" checksum="70979DC7A574E643" modified="2024-05-29" version="1">MDARCQCGAVSFKTPLPKPLRLYICHCEECKRQTGSAFGTSAIFPKFKLPKADLMGVYARPTASGATLYCYFCRNCGTRLIHATPDKNVVSVKGGCIDGLDWKTAVHIWTKNAMVPIPEGAENHREEAEYTDYGDQQEALDQPTDLRGSGGSPVGAVSVDGRCELSGTLKAIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFU6</accession>
    <name>A0AAD8UFU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_636712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359945.1">
        <property type="nucleotide sequence ID" value="XM_060509270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFU6"/>
    <dbReference type="GeneID" id="85393169"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF77">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1714129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56814" checksum="04E8F9FD64325A7D" modified="2024-05-29" version="1">MPSLLYQSAVALPWTPLVQFLGLIVVVYLFTTTLRSWARLSHIPGPFLSSLSYWSMFRIRTRGSRGYLEYVKLSTKYGELVRIGPNDLVTSDVQLIRRMSAAKSTYGRSSWYKATRLDPYHDMMGSVLDKSVHHALRTKLQPGYLGKDIPGLEASIDSGIADLVSLIRDSYATKLSPPGAENAEMKGLPEQKPVDFGRLAHYYAMDARSRMSFGQPLGLLRKDSDVFGLVAMSNLAIDILQFFTDIPPLQRIFTSDLALRLLGPKTTDKNGFGKIMGLAKEHVAARFGPDRKDEPDLLGSFIRRGLDQRSAQSEIMFPMVAGSDTAAKAIKWTMHYILSDFSIYKSLVKEIEDAIVEGRISVPITYQEAQELPYLQAIIYESLRVKPPFPGLVMKQVGAEGDIYNGIKLPPGTRVGHDVTSATHDKGLFGQDAEVFRPERWLEADAETVKLWKKQTELVFGAGRWRCTGKSVAFLELNKIFVQLIRNFEFQPADAEMFVKISDRGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG59</accession>
    <name>A0AAD8UG59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_633570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360978.1">
        <property type="nucleotide sequence ID" value="XM_060509045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85392944"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04497">
        <property type="entry name" value="hPOT1_OB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00976">
        <property type="entry name" value="Telo_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="2">
        <location>
            <begin position="1727"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1271"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1379"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1834"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="729"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="950"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="967"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1198"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1217"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1336"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1408"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1505"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1525"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1561"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1606"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1663"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1694"/>
            <end position="1710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1912" mass="204617" checksum="A78821CDD1A71C24" modified="2024-05-29" version="1">MSGVPQPAAQQQLEAAEAIAIAQLSPALQDPKARVVRGVVTITWPYSIVRKNIAFLLAEADFRLRRAKGQVRVEFAGSTAKAIADAALGSGDEISLSLDGVELVADDSKTRVPGTSLEWQLRFTERVLLQAKISDSEEVKVIDVDHPAQPESEPEELPVSILESFQDVEETPGPIATPAKTPLSKRPADHGLGADEFASPAFLKRARVSYGSLFDGGLDIFDEADDGAKARAKKKPKTGRYSSVWTYASRTPSPEPEAPEEEDTSMVVEEQPTVATPSRPTMVDGACQTVEQETSPPRDVQVAAEARQDPSYWQTPSKSTMIDSGVQSDLPLSPNIGLTPLGFGPPPPMPIFTSAHEQYPPAFQQPPIDPVFGHDMEPHYGAEGPFHEHPSAYPEAGLDHSPMHGHYPTTFLDEPHFGPDGVVTSQPLSEPIPAYQDHPQQHDLEAQPHHTVMVDGVAEPQQIPWGLTSAHYSRSPAKPAESGEVHEGRASSPQDADGETWEEDREREARDDPEDEEALRVEEDQMSEDQDGPEENFASRTYAERRHERGEEAASIEKESSPVGSGSGSGSESSGESDEEAEHEADDTGGDYDITHFRNLSNNQDDDAGTDLESDYGQEEEEEILDPEDDEEAEESEDYDEEGYDEGDYDEDEDQENQPPPAAPRGGPPVVIDLLSDSEDEDEAPPPPPPPAAAPRRQIPQYDGSADEMEDEDMDDQESQGESVRNEDSQQGSSPQPSDAESEEDQASQVGTPTPKPRQAAVSSAPDLTTGSIGDDFETMSPVKLPHMAGVPHSSSRPTSRGESDDLEAELERELEEEIAADDAGSDRQTPAPSEGMAGVEETGIVPSSPFNEDVRHAPPKQAASSPFNEGPAGDTALKQAVSSPVRTDIEDSEVLGEETLAVESPVAEESSPVRVVSAAEEEAGVRSMAEESSPVRSVAKEPAVKSMAEESSPVRPVPAVEEELAVESPVAESSPVRPVAATKKKPAVKSMAEESSPVRPVPAIGEESSPVRPVTATKKEAAVKFPMAEESSPVRPVPVVEEESSPVRPVSAAKEGPAVESLVAEVSSPVRAVGAVEESPEPETEAADVQVAPEEEDDVEPEELVTDEAEGQSLADQSEALVTESLQARIDDAAETEVAQAEDETVQPEVPAEDVTRQTPELEASNVEAPGQTEEVQQVDPDDKVAAKEQSPEHTEVTVAEAVEETVSVDATAHTSPKEATPDHVEIKETEVTKMEVEETQPQSDDEDMEVSLIPDETIVQDVEEATVEVHMDSDDEGSVEPADVDMGDPDDMSVDDEISSNATDSDMELDDVTQDQLIQSQLYEESMMYEEDQTVTTSITTTQVVEERPVSQGGDAADDARLETEVIETSRVTVETTITEPLKTTDAQQAQVEDAMDVDELEDAKSTQMASPTPTPQSFEEKTAETETSQADEQLTPRATQTVKSFSQSFVETQATEVTVPDDGEPQAEQLAEPLDERRPAESPAAAPVQPHEPLLDDEEEVEREKEASTHHEADADAPSPINEESSQIRDSSAQPSEAQSSLIAEDTSEEVVSAAKPTPKRGRGQHHRTNSKDQDPSVKLARASIASRRSTRLSDRTTPDIHSSAAAAPARGTAAAATTTSRGRSASLALKSDSPDADAEDTEVQPARAAVKSPSRAPKTAKESVTKGGKETVPKEAQTKESKAKEKATSKEAAASSTSQPTEQSSAALKAQLAKSLRADVPDCISLKVLRSHPGRTVDVLAVATTNPPEAKRAKGGPRGIMLAFNVTDHSIAPAQTVAVQIFRPHKAALPVIHQGDAVLLRNFSVMVLTRSGFGLRANDGSSWAVFETRRHGHGGEGQGGGDGSSADADAGDDLPQIRGPPVELSEGETGYAALLRRWYAGLDAKSLARLDKANEAAPAVGNVGKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGK2</accession>
    <name>A0AAD8UGK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_371440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363927.1">
        <property type="nucleotide sequence ID" value="XM_060502635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGK2"/>
    <dbReference type="GeneID" id="85386534"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="478"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="938" mass="104088" checksum="C53B68D9E0A144E5" modified="2024-05-29" version="1">MFNHSGDKPPRGVPSGSEYGGSQHGRLALNTSGQAYSRFGVPLNFGGPSTCPPPQQDSVRRDFDSSMDWTSPVAQQNARFDVGSSMNSAPQQDEGMELDEFSPPAGVSNLIARFEGIRAAPPSSNRIMSPASSVASPSIASPSSAHFGSMHGSTANMNSSGMSRITSPVAHSPATPTFFRAPESYRPPVPRHTKPVLDRAPSNIPMFTPDSRFGDGNSRMATAAGPSNPAPPPQVHHHQPQQYQPQQNQPQQHRHQPQQLQHQHQHQHQHQHQQQPQQPQQQQQQQQQQQQTADFSQLDPFLNTSNKGFQSQANAFNFPTANDFNNTTTKHFATQASNFSPQPNTFSAVSKPFASQPNAFSQSATAFSAANAFSSPANAFSSLPTTNTFSPPPNPNTFSPPPTTAFSPAPTPFSPATSTFSPVPTPAPSLMPGTPGVMQTPFGPPPTTSFPGHARAPSIAPTPKPATGSRPSREQVPAEAWESFKGTIKHLYLEERRPLKEVMQIMADQYGFQATPKMYKTRFSQWGFVKNNTEDEVKRLLSMKFQRDAEGKVSEFVRNGRVVNLGTYLKRKGVTEYDLVDFETPAQLPSYVRCRTPTPPPAPGYLRSPDLLRAQETIVGNMRKAFLHCRQFEVEIDKQVGWTSIMLWGAGSSDMFADANKKFEMGEHDAGGHQLMKAFKRLEMDLKQLSPQGIKELLLGMVHRDAGMMTALCKYLAAYSSTNFERSHPLRQTFSTLYEVQQKHGPITLSELVWGCIPTIAEELEAIYGRRHPYVARTWIDLAIFYNHANPERLEKLLSELQPLRRQIAGRHGQGSAEDLALRYAVVQLMQAAWPNADNTRMEALELWTAMKDGGLVFPVRGAEHNTFCYHSPLKIDPWERRCRERYDIGTQFFQQHCGIKVLPYFEEDMHYTEHAPDSHSALAAALGHMPQSKFSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGY2</accession>
    <name>A0AAD8UGY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH--hemoprotein reductase</fullName>
            <ecNumber evidence="8">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_677981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361560.1">
        <property type="nucleotide sequence ID" value="XM_060511175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGY2"/>
    <dbReference type="GeneID" id="85395074"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="549"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="992"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1719476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1237" mass="137068" checksum="309F74CE71389916" modified="2024-05-29" version="1" fragment="single">MSERSCPVSGSMGGGRCPAGAHGQTANRRVGPRGCSFSGYTQQGDLHAAFDIPRGVDVDEWLRARERKAINEIVYSDIPSADHIAQVKNVDTLVADDRDLLAVALGAPARQVILRAEGVGSQSGWKDGYLSAEYGFNAPDSNEAAGALANCPGRVWSDLCERMPGCVSRGRVRESVAALPLVEGTEEYVPDQALWAAIVALGMLCSIYRYEDKNDGYDGVSINSISTKPRVEMSDDLGPELIGIPRTIGLPYWQVSRRMGRAIPHLTFFDQASYNIKVRDPTSVYPYVGRFDNTDLRWPMFGERTEIAFLKGCADTSASFQHGPDAIAACQEHVMNRNNEGLLREMIRLKEILERMPNAFHSISTNPNSGDNYVSAAEWVRWGKFSAPLSKRCPAASGLQFPPYLLMDAFLGRKKYDSFLGNEGLHLRAWLPSNLRAFIASVEYHYRIPEYVRGSGDPRLMGVLDGIIEAYTGERGFMGTHRYKVFGILEVASKTGRTETNGASGASDDSGRPWEEVHRQFSDAMKERLEPYRGNIPVEPHEMRGTFEECRYKSRILSRSFVDSDHDRSISMVTLDLHNTGITFQPGDRLAIMPLNSWEECAKVAAALGLDTMLESPVLLDRKWSRFAEHLETVSNHGVASTSTKTRKLMVKDILRRGHLAPLTQDLVLKIHAMLRASSNTVLQVLATEEWPVRGSLGDLLQAAVMDTPTHIWDQAFDLSNDVAWLSDLISVEIPRTYSISNYPEELLPSTVDLTISRAEYKLCATFAGKSDISRSGVSSGYLNPPVGSPDDFIADEDELLVGISRPIAFQLPLDGAAPCAFFAGGSGIAPFRSFWQARAGRSVGKNMLFLGVQNREKFCYEDELRQYVNAGLMEVHLAFSRDSRGLAYDPIMRDLIERRTEPRYIDSLIVEQGASVCDLVMSKKQGGLGGYLYICGSVDVFDSVMSGLRKAIYNHRTATMESTDLIINTAFAERRIMLDVFMTPKPLPCNRPTIPLSQLSVHTGHRPGGRMWIAVHGSVYDVTDFSPMHPGGTLIMRSNAGVDCTKSFDNLAHTNNPEVASLLTKYFIGHLTPKPEYHDCEEISGLYDMWSAYLRTTVETLVSQQFEMDDILGSSKLWFQGSLINMLGVRIFYQYQSRLLQGGFSALFGPKFQELVLKLSFTMANAASVGSDTKLPDILGIIARAKTSTDAVTTSKEVSRIGQFICDSEPARLMERGIMDYANKSVQLDIELLEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH03</accession>
    <name>A0AAD8UH03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_585401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361443.1">
        <property type="nucleotide sequence ID" value="XM_060505844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH03"/>
    <dbReference type="GeneID" id="85389743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015225">
        <property type="term" value="F:biotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901604">
        <property type="term" value="F:dethiobiotin transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015295">
        <property type="term" value="F:solute:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905135">
        <property type="term" value="P:biotin import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000399">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000278">
        <property type="entry name" value="Putative MFS transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF33">
        <property type="entry name" value="VITAMIN H TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="515"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1719359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="545" mass="60345" checksum="2F21F6DE1549834D" modified="2024-05-29" version="1">MAHIHEEAHGADDKQPNEYSTPAGSSTLEPAAGPSHQEPEEYDVETVERVYRKLDLRIIPAFWTLYFLCSAIRSNIGIAQTMNAAQGHDLMSVLGLTAKDTSTALALFYVAYVIFDCPSNLVMAKLSPRIWMARIVIATGIIGTCFAAVQSAWSVKLLRFLLGVVIAGMWPGMSYYLTLFYPPSRTGKRIGMYFTAAQLSAAVVGLVSAGFQLMDGLGGLVGFRWMFLIYGLVAVVLGFCLLWWLPDRPLPPGQKRQRSSWLKWLPATPEALSGQDAVIHYNDLRRVYHPRPWTMRDLLQVLIDWRLWPLTFMYFGVVGVGIGTQLYGSVIIRSIVPTATSIQVSLLFAPIWIMDLIAILIMMPISDRFHGYRPFIFSAAVCLQIAGLLVVTFALDNGWARYGGLLMVGFGLGPTVPNCMTWTNEIFQRRHGEVGVAAATALVSGLGNLGSIVTTYALYTGWPEDAAKGRYQYRRSNYAMIGILCLSIASSFAMFFLLKVFGNKPVNKISSLDSSSEIEDGAARREARQRGFGKLFPRSNQNREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH34</accession>
    <name>A0AAD8UH34_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_18500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361204.1">
        <property type="nucleotide sequence ID" value="XM_060501547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH34"/>
    <dbReference type="GeneID" id="85385446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="56"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="604" mass="69736" checksum="1741210F2829418A" modified="2024-05-29" version="1">MESLTALEDIDDFWPRLTASEHADDYWPRRLLHIPTLTSVQRDEHSVYGTTEKPKYSILTYTWGRWKIRHDDHAVPVLPVKGVPWKIPSIKESHFTVDSFRSVVNSMAFEDVEWAWVDIACIDQEDEIMNAEEVGHQVAIFDKAVRAHVWLCESTQESLTKAFCDMNDGQLESITFSTFSTLENQLMPSYMTWEDVHHQEYRMTAVRETVDRISSGMQTVLQDPWFSSLWTLQEAVLRNDAVILSAEGLPCVWITSDDGRKYQAYLAMFVNFCNNIYLDLVNILRGLEYHKQMGYTLLDWEVDLKTKIGNMQSLLIRSGMYNLPTSNPNIPYSMAWSRQTSRPVDRIYGIMQAYNLRVGKVIRPHDNPSLADLVQKFAVAIVNKNPVLSQLFVRTEKPGDLSSWRITENSFVPANFRSPKGYVVKARFYLQGQDIMRARGMVCRLTDALEVQDKLVQFLKETDTSENAKFKDVDHHSDRIRIMTDAGFTQEHLNLNGHLWQLDLPGFRWLFPQKANLPSVLRDLWVFHVGDIDSTRGELFNIPESIAVLLRPANQTANSLSDSSEWADVPYMRVGLCTWGPEEEEGKRMMNEDIGWKSVDFEFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH78</accession>
    <name>A0AAD8UH78_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T6SS Phospholipase effector Tle1-like catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_459023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361563.1">
        <property type="nucleotide sequence ID" value="XM_060503220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH78"/>
    <dbReference type="GeneID" id="85387119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="Tle1-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33840:SF2">
        <property type="entry name" value="TLE1 PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="T6SS_Tle1-like_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T6SS Phospholipase effector Tle1-like catalytic" evidence="2">
        <location>
            <begin position="22"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="558" mass="63492" checksum="453C8A89AC955CA5" modified="2024-05-29" version="1">MADFSTLNGNASQESENKRTPRKLVLCFDGTGNTFTGSNSDTNVVKILSKLDRNDPDQYHYYQTGIGTYDINDESVNKGVFGEFKSSISQTIDQGIGTTFDAHVMAGYRFLMRYYDSGDKIYMFGFSRGAFTAKFLARMVHTVGLLCKGNEEMVPFAYRLYQRYLAGEVEDFIVSHPKKSKKDKKNKKNKKAPANGDVPTPPPELEDEEPLHEGHREDEDPATHGAKYAVARDEIAAFSDTFCRKEKAMHCGKMEESNIKVFFLGIWDCVNSVAVLERTAPVPVPVVGTAHHVRHAVAVDERRVKFKAALLAQDMKESDHTHEDIKEVWFPGCHGDVGGGWPASAESKLDNGIEMTFWERVKNFWTTRKEKAASKALGCDRLQLSDVPLAWMIREVKLVGQKEEVAALKWRENLEVFEKRFAKKKDKATMGVIHDSLAYGRGTSFFRVLLWKLMEWLPFITRWELEDSGWENVRFPLNKGSTRDIPKDAVLHESVLWRLKNDAKYCPQNNHGGRLLPCLKHKHNIAECHPIEEHIHDENCDHQIYKITRSASDLATRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI31</accession>
    <name>A0AAD8UI31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_355900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364381.1">
        <property type="nucleotide sequence ID" value="XM_060502547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI31"/>
    <dbReference type="GeneID" id="85386446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="22153" checksum="77ADC8E46C581601" modified="2024-05-29" version="1">MTKGQKNQKCRQLEALREQGGPSDGIAVGLGYKDTYATQPDRSPRNISPANSLMAIIYIVRSTGTCRKTIWLFAKEKESKRRGRAHPSDGKRSLRIRLRPSSFGQRSKSSLTFSFNPTAWHTSLSRSSGRNVLEIGPTQSQQGHRHRHGGWHMHGSLGSAWKGNKETVTIRKLLQRFASSTRASSRQHQVSANTDASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIE6</accession>
    <name>A0AAD8UIE6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF8213 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_754605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362178.1">
        <property type="nucleotide sequence ID" value="XM_060514497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIE6"/>
    <dbReference type="GeneID" id="85398395"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058526">
        <property type="entry name" value="DUF8213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26641">
        <property type="entry name" value="DUF8213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8213" evidence="1">
        <location>
            <begin position="14"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="139" mass="13724" checksum="0D94170D71B8D56F" modified="2024-05-29" version="1">MALAAPSAPELEKRAITCLKVGATATAKWTNSAGKSCTFTGIVGSNYGTNLAGSGDYSCNGRCGAGCTGTAVGNVYTQDCFSHDVCSYFNSASGGASDPNCGAAYNAAVDDTALGALNGCGQTNPSNAVSKPSTQPVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UII3</accession>
    <name>A0AAD8UII3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lon protease homolog</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_390115</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363497.1">
        <property type="nucleotide sequence ID" value="XM_060502782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UII3"/>
    <dbReference type="GeneID" id="85386681"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000002">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000091">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1 7 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="11">
        <location>
            <begin position="737"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="287"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="494"/>
            <end position="501"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="859" mass="94266" checksum="77086042BF26FDF5" modified="2024-05-29" version="1">MARSQTKTLPVIPLARGTILLPGVAQRIPVTAARPDIPALLANVYTRAASAAPNERIDSVPIACVPVSSPFVGPNGQLLIQDADQMDESLIKEVDPGTARKSDLYNYGVAARITGIEGRGTAEFALRVEGVARVRVEKVTQERPHFEAKVKYFHDEVTTDAQMQELFSLLKLRSRELVTILRISALLPRSPDSPGGLSPLLTRRLEMFINKKELKDAGQLADFMANIVEASYEEKLEVLAALDVKVRLAKVIELLDRQVSGIKNNFKITTFTSVPVQFLDKINDKTSRRVGPNGAPLPPNTMFPPGPNGVMGPNQDDDQEPNELEELKKKLDKAQLPPEPAKMAQRELRRLKKMMPGNQEYQVTRTWLDVLSEIPWTATTDDRLGPDTLARARKQLDEDHYGLDKVKKRLVEYLAVLRLKQSINDDVEEQIKQAEAEAAPPAEPEKEKEEDAEKAKKEEANAELEERAKLANTKIEVLRSKRMVDRSPIMLLAGPPGVGKTSLARSVAMALGRKFHRISLGGVRDEAEIRGHRRTYVAAMPGLIVQGLRKVGVANPVFLLDEIDKLGMSNVHGDPSAAMLEVLDPEQNNSFTDHYVGLPIDLSKVLFIATANSLDTIPAPLLDRMETIYLPGYTTLEKRHIAMQHLVPKQIRVNGLSDDQVNFDKEVVSKIIESYTRESGVRNLEREIGSVCRAKAVEFAEAKDGGQLGTYKPQLTVDDIEEILGIEKFEEEIAEKTSKPGIVTGLVAYSSGGNGSILFIEVADMPGNGSLQLTGKLGDVLKESVEVALSWVKAHAYELGLTSEPAANIMKERSIHVHCPSGSIPKDGPSSGMAQAIALISLFSGKPVPPTMAMTVCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIT5</accession>
    <name>A0AAD8UIT5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peroxidase, family 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_629957</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362286.1">
        <property type="nucleotide sequence ID" value="XM_060508789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIT5"/>
    <dbReference type="GeneID" id="85392688"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF7">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="30554" checksum="BBD7AC85F853D882" modified="2024-05-29" version="1">MKQSFTFIAAAFGVASANPHLAAAHLANPKFRRASPTEWTPAGPDDFRGPCPMMNTLANHGFISHDGKNLTKDVVVKGLQDGLNFGTDLGTLMFNMALIANPEPNATFFTLDQLNVHNVLEHDASLSRTDAAFGNNHVFNQSIFDESRAYWTKDTLDAQQLANSKLARQVTSRAFNPNYTFTATVENFSLGEVAAPIIVFGDMTAGTVNKTLVEYFFQNERLPAELGWVKKENAVTQEDILKVVEMIRNATVLTTGGAAEAPHKRMIRDLHTGLGLLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIU6</accession>
    <name>A0AAD8UIU6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_578175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364756.1">
        <property type="nucleotide sequence ID" value="XM_060505093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIU6"/>
    <dbReference type="GeneID" id="85388992"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.70:FF:000001">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme atg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000243">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006285">
        <property type="entry name" value="Atg7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01381">
        <property type="entry name" value="E1_like_apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="9">
        <location>
            <begin position="352"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="682"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606285-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="698" mass="78289" checksum="5B278507472A27C4" modified="2024-05-29" version="1">MAAIQYAPFSSEIELPFYAALFSSKLEHDKLDDSARRVLGQYSTLPVEPGQSCKMSILGNALTSDQPNDEHVRAEGFIKNVNTIEDFKNTDKQAMLKMAARHVWDAINDGTIYSVPSLLSSFTILSYADLKKYKFTYWFAFPALHSDPQWKRTGPIGRLDPKESTALVDRVGTWQANRDKRQNGFFLAKKARGVDVSDLDKDANSDLHDLNDTFGYVWEVANLGEFENGFFEDVAEEDRYVSFVDPSTYPENPSWPLRNLLWLVRQRFRQTKVQILCYRDIRSSRHAARSIILPLEMDPVEPLAVAAMPKVTGWERDGEGKLRARIANLGEYMDPTRLADQSVDLNLKLMKWRISPNLDLDTIKSTKCLLLGAGTLGSYVSRNLMGWGVRKITFVDYGRVSYSNPVRQPLFEFEDCLEGGKFKATRAADALKRIYPGVESEGHVLSVPMLGHPFTDEARSKADYDKLKQLIDEHDAIFLLMDSRESRWLPSVLGKSTGKIVLNAALGFDSFVVMRHGAEPTDVQPDDKERKTLGCYFCNDVVTPADSQKDQTLDQQCTVTRPGVAAIASALLVELFASLLQHPLKQHAPAPQTSADEKDPVDHALGLVPHTVRGYLHNFNNKVIRGESYPCCSACGPPILEAYRNDGWGFVKKALLEKDFVAELSGLAEVQREAERRAASMDWEEEEDGADDGDGELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJD4</accession>
    <name>A0AAD8UJD4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA adenine-N(1) methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_583210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BMT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362374.1">
        <property type="nucleotide sequence ID" value="XM_060505632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJD4"/>
    <dbReference type="GeneID" id="85389531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03044">
        <property type="entry name" value="BMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021867">
        <property type="entry name" value="Bmt2/SAMTOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008:SF1">
        <property type="entry name" value="25S RRNA (ADENINE(2142)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21008">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11968">
        <property type="entry name" value="Bmt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="301" mass="33860" checksum="7FF2720E7589A6AA" modified="2024-05-29" version="1">MGRTKPPNKLLSRGRPPTTKKAKSISRKETRTLINTHHTLQKKRQQALARNDEREAAAVAAEISALGGLEEYQRASLQGQRVDRGGDSSKVLLDWLRSANLQSSKSKDTQSEGKREGGAHRRLRMLEVGALSTDNACSKSGFFDMTLIDLNSQRAGILQQDFMERPLPMDDSDRFDIISLSLVVNYVPDHSLRGEMLLRTLSFLRQPEDDLSDTTRALFPSLFLVLPRSCVDNSRYFSQDRLVEIMTALGYVQLEGKATNKLVYSFWKRANTPSKPLPSFTKKELNPGMNRNNFTITLKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJV9</accession>
    <name>A0AAD8UJV9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_675206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362928.1">
        <property type="nucleotide sequence ID" value="XM_060511148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJV9"/>
    <dbReference type="GeneID" id="85395047"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19545">
        <property type="entry name" value="FUM14_C_NRPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="5">
        <location>
            <begin position="74"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="513"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="906" mass="99700" checksum="9078E0196DDD5D07" modified="2024-05-29" version="1" fragment="single">MKTASAARAIGLSLGLSDFFRYPKLSDLAKFASEVSTGVFEEQVAPFSLVPLDAALELRREAAQQCNTSPADVEDLYPCTSLQEGLISLSSKHDTSEAYISRKVFNLPSHINMFQFEEAWNITALAHPILRTRLVNTADQGMLQAVVRGPLSWSFGNDLDAYLAGDAQQPMTFGTPLCRYALIDMDSGVQRSPVFAWTVHHSIYDGMSMSIIQDAFWRAYIGQNVAPSPPFGKFIKFVKSIDANASQTFWKSYLDGPDLSFFPSVPSSISTLKPDSTVVRDFPWTWKSTNGLNASTLLKTAWAIVAGRYSGSRDVIFGNTLSGRNTPVTIPGLDVITGPTIATVPVRIRWEPKMTIMELLEAVQHQESDMRHFEQTGLQNISRISSDARGACQFSCLFLVQPPPTADQTRLEEVFGVEDRNKSSEYDDHPLSIECEMGKHQLRVIATFDSRVLHEERLERIVTLFQQTVLYLSSNSQSRVSSLNLVTDADVYQIQEWNAIPPTVVRRQAHDLFRHQARLRSYHTALSSWDGVMSYAQLDDASDRLAGHLHALGVGPDVLVPICFEKSIWAVVAMLGVLKAGGAFAVVEPSHPLDRKEVIVRQLGAKVAVVAPSTESLFPSGCVNTLVVCDASILKLPLPRRPLPNGSPENAMYVIFTSGSTGTPKGCVTEHWAFCSAMFEFGRDSGLRSDGQVLQFASYSFDTSSEEIFCTLFAGATLHIPSEASRINDLAGEIRRTKTNWAELNPKVASLLTPEEVPSLKTIILGGDRSHGSDVSRWPESTNLLNSYGCTEASVTSTLIPLNRRSNEEPPIGKGVGCNLWVVDPDNHDMLVPVGAPGELLIEGPGLARGYLGDPERTAKSFIFDPAWSNDGSGRRRRFYKTGDLVHANDEGAVFYHGRKDTQIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK89</accession>
    <name>A0AAD8UK89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_623254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364367.1">
        <property type="nucleotide sequence ID" value="XM_060508372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK89"/>
    <dbReference type="GeneID" id="85392271"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="86" mass="9709" checksum="F72FE128B4C5CAA4" modified="2024-05-29" version="1">MLPLSLFADNRLSSLPTRGSTRRNRTSYGQHHRPRFTLQLFVNRTTTLSLALVWPIAYLPFGPMAYVARSSLSVVMCLSIPVWDGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKH1</accession>
    <name>A0AAD8UKH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_274549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366027.1">
        <property type="nucleotide sequence ID" value="XM_060502084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKH1"/>
    <dbReference type="GeneID" id="85385983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="212" mass="22286" checksum="F1DB165EEABE8456" modified="2024-05-29" version="1">MLHTGVVDTGVLSLGIGGNKTQRTPPHTTRLGGREAGSTWIGLAWPACGMNPDATDPASVTLRLAGDGRFRSIRDSAANENGTAMRLKGPRPLPASLPGSLRPVSMRVSVFRTPLSVLMAKAAPMVTPARCLFGNLAVLSHRTAAPIPLGSASHKKSGVDGSVVWKLGWSTLAMWCGVQLAGLVGGGYSVLHLARLPVRQAIRDVLAWRDPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKS3</accession>
    <name>A0AAD8UKS3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Yippee zinc-binding/DNA-binding /Mis18, centromere assembly-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_578084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364712.1">
        <property type="nucleotide sequence ID" value="XM_060505084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKS3"/>
    <dbReference type="GeneID" id="85388983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="75"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="247" mass="27165" checksum="3E1D28DB395AF8F1" modified="2024-05-29" version="1">MAPNIVVSRPTFPTYLLPSFNIIPFRRRRAPRRTSSASEAAAEIETASTSPDSTPDASQNNRNNKATSLARTQPDTLRCSTCSCDIAFASQIVSKGFTGRYGRAYLIAPTGSLANVRIGKCENRQLVTGWHVVADITCVLCSAKLGWKYVDAKELSQKYKVGKFILEVERVVPFRSWEDDGADRNGDDSGGDDSAAQTARKGASDSDVEVVFDSEDEDDLEDMFSGNWDPEVVAKRRSRRVATARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULJ4</accession>
    <name>A0AAD8ULJ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_621041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365117.1">
        <property type="nucleotide sequence ID" value="XM_060508223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULJ4"/>
    <dbReference type="GeneID" id="85392122"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="77" mass="8946" checksum="20BF2408FBADDA8B" modified="2024-05-29" version="1">MVWLCLVVSVSFGSSPVCLIHLKIPVQHLDQSCPRKMRSLPYLLSRLSPTERRRLMLLTRILAKREKRSSSMALPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULZ8</accession>
    <name>A0AAD8ULZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron permease FTR1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_580048</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363846.1">
        <property type="nucleotide sequence ID" value="XM_060505306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULZ8"/>
    <dbReference type="GeneID" id="85389205"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="326"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="366" mass="39794" checksum="490F930B7B7F98E3" modified="2024-05-29" version="1">MTVDVFSVPVFLVVFRESLETVIIVSVLLAFLKQTLDGPNRDVAVYKALRRQVWLGTGIGFLICLIAAAVVIAVFYKVGRNSWEAHELYYEGAFSLLAAVIITIMGAALLRIGKMQEKWRVKLAKAMESPVKTGASRGWFKRFAEKYAMFILPFITVLREGIEAIVFVAGVSFSAPASAVPLPAIVGLIVGAFVGYLLYKGGSTAKLQVFLVISTCLLYLVAAGLFSRAVGDFEQQEWNKVVGGDAAELGNGPGSYDIDKSVWHVNCCSPELNGGGGWGIFNAVLGWTNSATYGSVISYNVYWIFVIGCFLLMRFHETKGHWPLMKAKAPREADRRLSDDRSGSEQASTSEKDKGAATTKTVTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM41</accession>
    <name>A0AAD8UM41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SPX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_578588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364530.1">
        <property type="nucleotide sequence ID" value="XM_060505143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM41"/>
    <dbReference type="GeneID" id="85389042"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="586"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="654"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="722"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="767"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="810"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="839" mass="92030" checksum="F08195795AAEF84E" modified="2024-05-29" version="1">MKFSHSIQFNAVPDWSSHYIAYSNLKKLIYQLEKTVHQTSTGDVESRPLIRNEEPEDVFSRALGVELEKICSFYVSKEGELLDEVNQLLGDVGNHSSEDDENDGEPRRSFGSASRPGLSVNGRRTSVSIDGNMEDSDDDEDDDETTGLTKSRSSLGGGRRKTAPNLGHSVTDMTASTDLTLGRSLRRYSTANDEMPDQTFLYSSGIMLKKRIISLYVSLCELKSYVQLNRTGFRKVLKKFDKILDKELRVKYMTANIDSAYPFKPENIKSIEENISKMEKAYAEIVTQGDEGLAKRDLRSHLREHVVWERNTVWRDMIGMERRAEAASLGRGLLGRDGATGSRRLQGDDELAPITKEVVTPVGRFVVPTWVANTPLLTLLIAVGVFLLLLFLPIMEKPEQQNCLALLVFVSILWATEAIPLFVTSLMIPFLCVVLTVVRSEEKPYRRLDAKATTAYIFSAMWTPVIMLLLGGFTLAAALSKCKIDKRLATFVLSKAGTTPRTVLIANMLVAAFASMLISNVAAPVLCFSIIEPMLRTLPSESNMSKAVIMGIALASNIGGMLSPIASPQNVVAIGIMKPAPTWIQWFFIVIPVGIVSLLLIWILLLITFQPSKGTTIAPIRPVKEKFTGIQWFVSIVTLITIGLWCGSHQMESIFGDMGVIAIIPIVLFFGIGILTKEDFNNFPWTIIILAAGGLSLGKAVKSSGLLHTVAGVVTKEVEGMSLYVVLVVFSALILVIATFISHTVAALIILPLVFDVGSNMDEPHPNLLVMGGVLMCSAAMGLPTSGFPNMTAIMKEDPTGQRYLQVKHFISRGVPSSILTLVVVVSLGYGLMRVAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM69</accession>
    <name>A0AAD8UM69_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dehydrogenase FUB6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Fusaric acid biosynthesis protein 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_575480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365983.1">
        <property type="nucleotide sequence ID" value="XM_060504818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM69"/>
    <dbReference type="GeneID" id="85388717"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="20"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00069006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00083301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="37026" checksum="0759B7CECA3DC38D" modified="2024-05-29" version="1">MTQNKTLIFKKIPTGLPVAGEHLTIEDRPIDLNDAPEGGLVVEVLYASFDPYQRGRMRDAGTKSYSPAFELDGPITNSTVGKVLKSNSPDFAEGDLVYSHTPIAQYARVTPQILQQGRKVQNPHNLDLGLFLGPLGMPGLTAWSGLHKIGQPKKGETIFVSSAAGAVGQLVGQIAKREGLTVIGSVGSDEKLDFITKELGFDAGFNYKKEKPAEALPKLAPNGIDIYFENVGGDHLEAALTSMNTEGRIAVCGMISNYNTPADQQKGINGLMQLVTKQITLQGFLVGNPKFGPAHFKDHQENLQKWLSEGSVKSKLAVTEGIDNAADGLIGMLTGKNFGKAILKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMC3</accession>
    <name>A0AAD8UMC3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_614507</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367017.1">
        <property type="nucleotide sequence ID" value="XM_060507838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMC3"/>
    <dbReference type="GeneID" id="85391737"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="348"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="565"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1726962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="822" mass="92066" checksum="4512C93B9B275AFF" modified="2024-05-29" version="1">MPPKRKAQGAATGSFKAGKGSVASTPGGATPRSIASDNESVADPVSESEDENLEKNVDKFSVEAYLDRPKTNGHESMTGLFKKKRDFSFLQLKPDYQNRPLWIDPAKGRIFLESFNPLAEQAQDFLITIAEPISRPSFVHEYALTTHSLYAAVSVGLSPQDIINTLDRFLKMPLPDSIRKFIEGCTQSFGKVKLVLKNTKYFVESTDPVILQKLLKDSVIGPLRVHGTEEITTIAAPKQGPLVIPGTANAAGVRQAEEQKAKGREGEVKEGEVYAALNDDDDDDQEITHAFEIGDEAVETVQKRCLELEYPVLEEYDFRRDEANPNLEIDLRPGTLIRPYQEKSLSKMFGNGRAKSGLIVLPCGAGKTLVGITAACTVKKGVIVLCTSSMSVVQWRNEFLKWSNIKPEDIEAFTSDNKGRIFPGNTGIIVTTYSMVTQTRERSHEAKKMMDFLQTREWGLMLLDEVHVVPANIFRKVTSSIKTHSKLGLTATLLREDDKISDLNFLIGPKLYEANWMELSEQGHIAKVQCAEVWCPMTTEFYDEYLKASARKRALLYIMNPRKFQAAQYLINYHESRGDKIIVFSDNVYALKTYAEKLEKAYIFGGTGQAERMNILQNFQHNPQVNTLFLSKIGDTSLDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSSKRQAFLVDQGYAFKVITQLANIEKTPGLAYAAASERRELLQKVLIENEAGGEDEVIDDLFHSGTMGRAPARGRKKAAARRTAGLLGDLSGGQDMAYMEQNKRVKLKKAKGESSAFFKKIQREKAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMQ5</accession>
    <name>A0AAD8UMQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_718260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366721.1">
        <property type="nucleotide sequence ID" value="XM_060512047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMQ5"/>
    <dbReference type="GeneID" id="85395945"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="48172" checksum="D14960ED6E956485" modified="2024-05-29" version="1">MASTLPPPTGSLISGLVFEDKPYDVTRDDPLRVFQQNVSRVRAYVEKRLADFDGLGTLVELKLGDGSQYLSPPIFIDSTSTSAALLDNIPDHVRPGVTVTIMPEYILDVIEGRMHAVHAFGKRAKPPCRGSFPMCFAPGGRPQPVVNADKLGPQDLPKPTEDVQQIKRDLQKWGYAMVKDALSADQVEILKTAVEEQAAGERLAGVAHMDGAHVHADDQPNQRVWSLPNKGDEFLDLLNHPLIDAIMPWFLGNAFKLHSMGANIARPAKSGIYMHRDQMGLTPETIDHPYLLNAMWYLVDVTEERGATRMYPGSHNKNVAPLVIDQVGGSVPAAAPAGTCVLLDSRTWHSTGVNTSDVTRPIILSAFCRFFLQAMESYPELMSAETKAKLSDRQLGLLGFRVPGKRAQAYTAYNYPGADFGKSRASADVAWLPNNTNGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMR8</accession>
    <name>A0AAD8UMR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_581288</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363275.1">
        <property type="nucleotide sequence ID" value="XM_060505441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMR8"/>
    <dbReference type="GeneID" id="85389340"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000016">
        <property type="entry name" value="Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="10">
        <location>
            <begin position="14"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="11">
        <location>
            <begin position="269"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1723220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="461" mass="49449" checksum="0F5B0525746DBD96" modified="2024-05-29" version="1">MAPRQQRQKAPCYVLGVGMTKFIKPRGKVDYTELGFEAGVKAMLDAQINYDDVEQGVACYCYGDSTCGQRVFYQFGMTGIPIYNVNNNCSTGSTGLAMARSFVSSGAADCVLVVGFEKMMPGSLQSFFNDRENPTGTTIKMMAETRGITNAPGAAQMFGNAGREYMEKYGAKAEDFAEIARINHEHSTKNPYSQFQDVYTQEQILKAPEIFAPLTKLQCCPTSDGGAAAVLVSQAFLDARPHLKDQAVLVAGQCLATDAPSLFSRSAIDLMGFEMTQHAVKAAMGEAGLTPKDVQVVELHDCFSANEMIVLDSLGLAEPGKAHELVRRGDITYGGKYVVNPSGGLISKGHPLGATGIAQCAELVWHLRGWANNRAVKGTKAALQHNLGLGGAVVVTVYRRADGKEAPAIDSAAVGKANKLGYNPAVEAKGFTAQQAAAVRSKTKRSDWALQDTEEKVEARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX9</accession>
    <name>A0AAD8UMX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_790930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366841.1">
        <property type="nucleotide sequence ID" value="XM_060515724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMX9"/>
    <dbReference type="GeneID" id="85399622"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="312" mass="35333" checksum="835086F03A0D53D3" modified="2024-05-29" version="1">MAQSSSDSSQAEYSHEATVAAITSYYELLARVHPDSVSSLEYPPSGGWPQITPESFSILGRNNTVIELMRHIPYFTSDRISFMKSTTPRNFADSSFCRRTHEESRVYNEEVRPVPQDKIGANPGYSPEGGGVPIPSSMFTLAMLAEEKEEGYDILLDTEHNIVIVVRVGEEFPHGWPPVPPDANHINWGGDDKDEVEGEKEGESDGEDSEDSEEDVDLYLLGHDWRYSPTYRIHTFFNMCQEQWKVMDWMPKMEWAGQIEEGYRSAETKLDETYGDGLRQKIMREAGWPGTGEAVGMGWDKAKAEKQMIELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMZ4</accession>
    <name>A0AAD8UMZ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364829.1">
        <property type="nucleotide sequence ID" value="XM_060514186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMZ4"/>
    <dbReference type="GeneID" id="85398084"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="9204" checksum="D3462361213463BE" modified="2024-05-29" version="1">MQSVHIKHGSIRQGKFDIYWSKDNEWAIIDEEEEENERRLKELHRLSTRYWSAGLLVVLVPAMCGLLWCCRFRRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN07</accession>
    <name>A0AAD8UN07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_318931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365010.1">
        <property type="nucleotide sequence ID" value="XM_060502359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN07"/>
    <dbReference type="GeneID" id="85386258"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="149" mass="16167" checksum="19338065CBDDA498" modified="2024-05-29" version="1">MSSWPKPWGLTAGRVVWINGFAMIVAAWFGAELPSCCLSPEDRYWNVTVSEGFRGTFFDGFSKETGLWGLFYGVRVVMISKGSYTPCASRLLSFSSRRGVAGRRGRSGLVGLAVTARYGQASNIPLLSHSLALPRKSLRVAGHMHPAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNF3</accession>
    <name>A0AAD8UNF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_620840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365280.1">
        <property type="nucleotide sequence ID" value="XM_060508216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNF3"/>
    <dbReference type="GeneID" id="85392115"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF3">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="22559" checksum="961B6288F938855B" modified="2024-05-29" version="1">MTDLTHFDLLPLQLDPQSKSLSSTSSSRALAAELSQLNALHRSLITSDTTTQHGVPPPPMPVNPKRSAQVAKLRDSGNAEFHKKKYGDAIKFYTLGLQMALTRPLWEPSQLVREEVSGLYANRAQAHMALQQWAEGSVDAEASVEARKVGNAKAWWRRGKCLMEMGRLEEAREWVGKALEYEGEEGELVAQYKEIEARLEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNX5</accession>
    <name>A0AAD8UNX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="9">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="9">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="9">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BNA1</name>
        <name evidence="10" type="ORF">BDZ83DRAFT_718637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNX5"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000093">
        <property type="entry name" value="3-hydroxyanthranilate 3,4-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF1">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1726232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="182" mass="20481" checksum="5980B12FDBD65EFF" modified="2024-05-29" version="1">MLGPPVNLPKWLEENSHLLKPPINNYCVYNEDFTVMIVGGPNARTDYHINQTPEWFYQYKGAMMLKVVDEGVFKDVIIREGDMFLLPGNTPHNPVRFANTVGVVLEQRRPEGSLDRMRWYCETESCREVVHEAAFHCTDLGTQIKAAVEAFKADEGARTCKKCGVVAEAAPKPGSIKDPNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPN5</accession>
    <name>A0AAD8UPN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_285752</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365684.1">
        <property type="nucleotide sequence ID" value="XM_060502163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPN5"/>
    <dbReference type="GeneID" id="85386062"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="398"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="235"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="411"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="52230" checksum="CD40E37313B0C669" modified="2024-05-29" version="1">MSYPAPVQLSRDDTSEKARIVINSGGENGNVAFEGEASSGIDFTSNLGDPTRSTTDQEGKKITFNTTTFSSHESTSYVITVDRTFQTIGWKLASGVKLSKASWLAKPNEETESLIMEAFPSQENPGPISGRSSAGFAPPTAPAVKRQETYAMTLGNETLVLPIDAKKMATYSGSSMYIELQWISETKSGTTTSGAFAVFTGPYPSVEYDQAVGKLADKRGASEVERVGSEDESDSTSPLPTSTTQAAASSTASLNPNASQSTIGGGSSSDSGSSSGGGGSNGGLAPGAIAGIVIGSVLGLALIAFLIWFFLRRRRRRADHVSDGAYGTGHNPHEYLADKETHARVTESPHSPYTDDGQHQHSQHQLHQQQSQPQEQHHLSRELHQDDHNDAFETTTAATAAAAPASAVSATDHHQPPFAPYREENMSTASRSVEDMTRSGAGGPRSSTPNVNSNVSHLIEDGMTEDEIRRLEEEEMALDAAIEQAGPRRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQT4</accession>
    <name>A0AAD8UQT4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BDZ83DRAFT_138766</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368341.1">
        <property type="nucleotide sequence ID" value="XM_060501268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQT4"/>
    <dbReference type="GeneID" id="85385167"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000016">
        <property type="entry name" value="Calcium-transporting P-type ATPase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000193">
        <property type="entry name" value="Plasma membrane calcium-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="788"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="825"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="872"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="911"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="964"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="994"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="43"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="22">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAK1728286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1036" mass="111946" checksum="7CAB70AE262F1E25" modified="2024-05-29" version="1">MGEPEAVRHGEHNTAAAEVNPEQDEPPSIPRPPPIPNPVPHWPAHSVPVTDIGLLWQTDLENGLSKADAAARLERDGPNRIEGAKGLSVWEIVMRQISNSLTLVLVIVMILSFAIQDYIEGGVITAVILLNIVVGFVQDYNAEQTIQSLYALSAPTCKVVRDGIAETIKAETLVKGDLVMIAVGDVVPADLRLLEGINLSIDEALLTGESLPISKHPEALFEEADIPLGDRINMVYSATTVTRGRARGIVTTTGMETEVGKIAMMLRTTRKRDENASLPARALARSKAAMKSILGLEGTPLQVKLSKFALLLFGLAILLAIIVFAVSKFDIDDQVLIYGICVGVAVIPESLIAVLTITMAVGTKAMASGNVIVRKLSSLEAVGGVTNICSDKTGTLTQGRMITRKIWLAEDTTAIIEGTTDPYDPTSGKVRWPGSTASSSGSSGASTPTVEKSDDTIISSSFGAFLKAIALCNNSAVTDGKASTDTESMTTATEVPVSWTAIGEPTEIALQVFAMRYGKGKTDLISSEKTKMLYEFPFDSTCKLMSVVYEFPGAPRQVFTKGAVEVMVERLAESDDVKQRIAAKADELASEGLRVLCVAQRFLEDAENASERNETECKLRFLGLAGLYDPPRVETLGAVKKCNTAGISVHMVTGDHIKTATAIAHEVGILRGGEPSTAVMAAGQFDAMTDAEVDALEALPLVVARCSPMTKVRMLEAMHRRKAYCIMTGDGVNDSPALKKADVGIAMGKRGSDVSKEAADMVLTDDNFASIVTAIKEGRRLFDNIQKFLLHLLISNISQVILLLIGLSFKDRSGTSIFPLSPLEILWVNLITSSFLAIGLGLEEAQPDILLRAPHSLRVGVFTWDLIRDKMIYGFFMGSLCLAAFTSVAYGPGAGDLGSHCNDGWNETCDVVFRARSTVYATLSFLLLVTAWEVKHFQRSLFNMNPELWTGPTAVFKTIFKNRFLFWAVAGGFIMTFPVIYLPVVNRAVFKHGMITWEWGIVVACLVVYIALIETWKAVKRHMGLGMIARSPEGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR19</accession>
    <name>A0AAD8UR19_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_752239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364910.1">
        <property type="nucleotide sequence ID" value="XM_060514170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR19"/>
    <dbReference type="GeneID" id="85398068"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF15">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="200"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="470"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="709"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="780"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="99963" checksum="B4C59EAB3781C13D" modified="2024-05-29" version="1">MDPSGIIGIISVVAQIVTTCSKLGLSWRDAPEDAKKFKNEMDGLYKTLSETSSLLIQNPDFIAAFEGQHSAVLSNLTTLSSPDDESLLSACQEELARVLKGLQKQIEGSRFGWQRFKAMFSGEMTQSAIENLQRRCQVINSMISIDNTTLAVKTNLEVQSLKKILAGRDLDESRRRILDRITSIDFTAQQIDNLDRRQEGTGKWLLESPEFEAWVHGDRRTLFCPGMPGAGKTMLSSIVIEHLKRRFEGNSLVEVSFMFCNFRRHDEQTPRDLLASILKQLYCTTPAECGIVEKTYEYEISSASRQDIIHCLKAVVLQFSRVYIVIDALDELDDNRNMLLEAILNLQETSCVNIFATSRHIPEVERYFDGTPHIEIRAVDGDVMKFLDGQISKLPLAVRKNEDLQDQIKTTIVQAVQGMFLLAQFHLDSLQGKRSAKAVREALCKLSSGSEAYDVAYEKAMERIDRQLEDQKSLAIDALSWIVCARRPLKTMELQHALAVERGTTELDEDNIPELEDVVSACAGLVTIDEESQIIRLVHYTTQEYFERTKGRWMPEAQRLLSTSCVAYLSYDRFQFTFEEHLERLHLDTKEKHMISQFRGYRFSEMVKELVTSENPLYDYAACNWGYHAKYIHPPDQDTLSFLTDRGYNRSSSFHVLLDKSKFAFKLFYWRPPPRDVRGVHLAAYFGLIRIFELLEGTEKTNLNLEDSYGYSPLFYAILGGDEEFLKYLLAQGGLRLNKKAGPNKSHMFPLQIAVNCENKAAVRDLIGTNRVHLGAKDFLGNTALRHAAFCGNVDIFKLLIETGKVDIELDASERPMRDRVTLRTVQWLLDEGKVDASLLTRTSSGKTPLDLALKNRKPEDPVIKIISDRMTFLKTTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URF7</accession>
    <name>A0AAD8URF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7598 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_571193</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368158.1">
        <property type="nucleotide sequence ID" value="XM_060504386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URF7"/>
    <dbReference type="GeneID" id="85388285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056019">
        <property type="entry name" value="DUF7598"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24535">
        <property type="entry name" value="DUF7598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7598" evidence="3">
        <location>
            <begin position="14"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="275" mass="30512" checksum="AA1D1EE2D5A84009" modified="2024-05-29" version="1">MFNLSENSSLRGSGHLILNVFRAFNIIGLLAVSAATWTMIVMSILKGNFAFFDSASRFFTFCFAVFLIVSELNVFRAYFMRNWPTLSPEHGLSWLGVAMVVMGCHVLGGITVPAYSVETIGLPLWRLILASGILAITFGFFNIISSIVFRDGSNGINARNIRSDGTLASGKNSYADGYSVRSNSIRNEKPNNKFKRLTQKFTPWSKSNDDTSPRPNISHPIAHDVEQGHESEPDYDESRRSPIMPDISRPATALHPAMAGHRHTKYSLASNVSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ1</accession>
    <name>A0AAD8URJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_117504</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368731.1">
        <property type="nucleotide sequence ID" value="XM_060501132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ1"/>
    <dbReference type="GeneID" id="85385031"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="545" mass="61975" checksum="3126795AC933D2F1" modified="2024-05-29" version="1">MHGITETILETFAQHWLSIGLSLIVAWLVKNRYNNGLNKYPGPFLASLTDWWRFFDVKGCRPEVTHQKLHAKYGDVVRLGPNTLSFADPAALKSIYGLNKGFVKSDFYIVQQSIAKGFRLESLFSTTNNDFHSQFRRCVNSAFSMSALVQYEPFVDNTTKLFLSQTEKLFAGNPEGCDFTTWLQFYAFDVIGEITYSKRHGFIEKNEDIDGIVAYLGKLFLYVAPIGQIPFLDLLLLKNPIYLKLSQWGFIDATFPVARFARDRMAERLPELDGKEPLLPVTSGKKLAEQPDLLSKFLAAREARPEFMSDILVQTMAVSMAFAGSETTAISLAAVFYYLLRTPTALARLRDELDTFAREGGFSDNETGLVTWTESQKLVYLDACIKEAFRMHPAAGLPLERIVPDQGAEIAGHFVKGGTIVGCSAWIIHRRPEIWGDDVDTYRPERWLPEEGKDAAAEEKRIKEMNGHMFQFGMGSRTCIGKNISLLEIYKVIPSLLRRFDISFKDPSQEWELVNAWFVKQNNFQAKFYRRDIITKDSVNEKVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US94</accession>
    <name>A0AAD8US94_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fimbrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_717791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367545.1">
        <property type="nucleotide sequence ID" value="XM_060511988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US94"/>
    <dbReference type="GeneID" id="85395886"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032432">
        <property type="term" value="C:actin filament bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110009">
        <property type="term" value="P:formin-nucleated actin cable organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21294">
        <property type="entry name" value="CH_FIMB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21303">
        <property type="entry name" value="CH_FIMB_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000042">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000010">
        <property type="entry name" value="Plastin-3 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000016">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000027">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="139"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="287"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="412"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="537"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="649" mass="72346" checksum="C8F2D12175524308" modified="2024-05-29" version="1">MNVLKLQRKYPQFPQNEIFGLSDAFRKLDIDEKGYVDEATAIKATQQSERQPYDVVRQALKEVDLDSSRRVELEDYVALIAKLRESSPAQKRMSTGPGGGTGASIVAQATGGMGHSSKSSIGKIHVQGSNANVTHTINEDERTEFTRHINAVLAGDADIGSRLPFPTDTFEMFDECKDGLVLAKLINDSVADTIDERVLNRPKNKKQLNAFQMTENNNIVIESSKGIGLSVVNIGSGDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKAAGWNRRVNNFSSDIKDGENYTVLLAQIGSEYGATRAPLQTRDLHQRAEEILQTADNMGCRKFLTPSSLVAGNPKLNLAFVANLFNTHPALDPITEEEKLEVEDFDAEGEREARVFTLWLNSLDVQPAVQSFFDDLRDGTVLLQAYDKVIKGSVNWRHVNKPPAHGGEMLRFKAVENTNYAIELGKQNRFSLVGVQGADITDGQRTLTLGLVWQLMRRDITVTLSTLAQRLGKKEITDSEMVKWANDMSRKGGKSSAIRSFKDPSIGTGVFLLDVLSGMKSSYVDYDLVTPGHTDDDAYLNAKLSISIARKMGATIWLVPEDICQIRSRLVTTFIGSLMATAEKQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USF1</accession>
    <name>A0AAD8USF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_536223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366948.1">
        <property type="nucleotide sequence ID" value="XM_060503361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USF1"/>
    <dbReference type="GeneID" id="85387260"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="742" mass="83273" checksum="756F6E37D6982B3C" modified="2024-05-29" version="1" fragment="single">CDVEEVLKKVLPRSEGAAYYPEFDAAGLYVQSEDGLKALWHVETERLMKIAKNPDTPLDFSSKRFLQGDTEKGYRDLSKFCQKVLTAITICLLDNECINAEHCGQLSDHHRLSSLIRQVSKGQGAAESFASMGESEPQEDALRSLGATYELINYISAVLTRLIVQTSSGSYWQTNVLSVLIKRITKIKLLLIDLHANSTIAVRAAEAILSKVRESGDTQQKRGEMDEEEECEEYMRMVEANEKEGTASFEDSQVAAHCVEQNKFRFGLNSALRHILMSLRFINRSGLPATSFEICAVAYETGFEGFKALLFQDRDLEYSATSDLDNMNTAHSAFNILNQIVMHLKHQSHEHEAYTNGLKTTLQWRYSGDEDNRSGQVDIDLVGYSQRLQLNSMDEVITVMVPLVMTCPVFLSDFTSFRHVMALTGFIQDDVQPLAEGKFGAFFRMYTSEFASMKRPDVLHLSEALECGFFSRSGLVRSSHPPPREQHDATHRLNELKKLTEYMDEWVVDETCVTVSCPGYVWGVIFTAVLFAAGGLGIGFSVGQRINGVDPSNLATYLWVVAAFIVLVGKSMKVKEWTWNDFLRRRVRCCSVSELQSVTRIDGQLIIAKLLHDERRGSVLNIRGPYNSAFLRRSTEGFSIDRPISSSTLLISGLTMLKVVTAKGHALVCLDFRRGTDLRVIAHTPDPRKEHLICEQIDRLQPGASATADGAQSQTKHAFSRSSELKWKRVQGIYPQMDAKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USR8</accession>
    <name>A0AAD8USR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_613772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367274.1">
        <property type="nucleotide sequence ID" value="XM_060507776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USR8"/>
    <dbReference type="GeneID" id="85391675"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223">
        <property type="entry name" value="BETA-LACTAMASE-TYPE TRANSPEPTIDASE FOLD DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36223:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR EAF N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="1">
        <location>
            <begin position="9"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="326" mass="36984" checksum="812C2DAD4F08706B" modified="2024-05-29" version="1">MAVIDELKGVKVTVQVNGQEAIEYDDPDGLENDVNRKHATHRTFNYIESKDDTCFTVKYEVGNMHRWESPKSAFSLYLYVDGKRMDSVVCEASRFNQFAPSYKWSTVVEGSRGSSRDPSYDRLSKFKFSQVTTVDDATKERVEGDSQKAKSLGVIEVFVYPLTITGPSYSSGHEHYRDNQNSTFNIAEKALKGRAVSHGTSFTDGGFVSKRKSVCAEYLNGGNPIACFMFKYRSRDALQKELIIPRSPSPEAIDELSEADIRRLAAERLDEINNGRRSGTVKQERKGPIIKREFAEIYDLTEEPAKREWKKIKIDVNREAIDLTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT46</accession>
    <name>A0AAD8UT46_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_728223</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368402.1">
        <property type="nucleotide sequence ID" value="XM_060512801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT46"/>
    <dbReference type="GeneID" id="85396699"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="582"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="641"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="750" mass="84599" checksum="E513FDD9E062A7EF" modified="2024-05-29" version="1">METPNPYRASGRPRKGLQICFQCRNRKVRCDGEPGGCENCRRLKFHCSFAAPDQLPDAANSSTPSSSDPSHLRLEKRRVRTACIQCRDKKTKCCGTHPSCRRCSHRGVDCQYPDVSKSSSSRNPNSDLRHQPPATVRGGSENSMENRTSSMNRDSSVAHLPASSLGLELNSNKTIIKQHIDAFFDFVYPIPCYGFIHKATFCQSWAQDTYNPRLLKAMCGLTARYIASGDSIRLQQATRWIQESEVQLLMRLSEPSMSDIEALMLTTLDHIIARRFSKMLVSACLAARLAFMMRLNYEDGRLSFLTQERRRRLMWGIYTMETLYSSGRTEFTGCPKETIHLQLPCHERSFTLDIPVMTEPLKPPENQCSLELGLMAYNIRVLDIRDRIQRLSHTITHHRKPLVECVSLLKGLVDELDALRRSLPPQFAFDKKNLFLRVYTPQRTPFVMFHTWWHQCQCDMYRFTIPGFREGLPVEELQTLPQDLVSFCRDKCLQHALAVANIMATVNDMGNDIFITDPALVMCTFHSARVISRLGSSQFANLPKDILISKLKACSDILETPAEIYPTTKLLRGGIADLIHDAERDSGDSSPLRSNWEAEQPGSDTEATGAQQPGVQRGTQGSVIEVYSKYSVTDEIRKLKFQQDGEEDREEYRSDAPALGTGADGVTPQQFLMTDMSKENGPQPHMPMPQDMTANAFGFSEAGFGTSAAPYDVSMTLGFEPNYGECQPDLFLDTFMPLQNDWNMADSGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTR3</accession>
    <name>A0AAD8UTR3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_232884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367024.1">
        <property type="nucleotide sequence ID" value="XM_060501818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTR3"/>
    <dbReference type="GeneID" id="85385717"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF97">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10890)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="250"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="698" mass="74682" checksum="C4E7383FC7765EEE" modified="2024-05-29" version="1">MASTGPSKSPAARPNTIRAPSFTRQSEDSDPLRVPKRAQTFQNGTAADPLTATTTTPVVASKVQQKPADEPEGPDAFETAGRPSTDNDDGFDGRGSVDLGELPIELVSLTDSFVETLSSKSHPAPLTIDNVSALFQSFYETASTHVNTHISSLITRHNRDASPAPSASSKVSTASRLRAKAASLGSKDKPKNLPKPEPEQQMITAEELANKKKARKAIEAKRGIIEEAVERRLCEGIYDKIYRHKSTQDEAQDSKLRSKTAALALVGIGPADLGIDLGDDASQTPETAAEKVEEIKKSLEQARRDLILMNEKRYPLGKVHHLKAAHKDIVETLAQFHPSASADEIMPMLIFTLITLPPEHLNVISDLHFIQHFRWEPKLTGEAAYCLTNLEAAISFLETVDLSTLRADELPQGPARGMSQPGTPRAETFPPAFPPGLTVTADPSVETDSGNATPTRPPASPSASAGLRAAVQARNRRLSELVNTPAQAIGAASDAVLNTADQHIKTISTSLGDSYKFLVGKLRETQGTPTESGQGLVVPKTLDDARKLMSTPPPEEEGSISGASSVHGTEEAESTRRPPVREDKVLNLIGGRKASRDHSADSSRSVNSSRKVLFAKEGEKDLPTPSPGNATNPLDSVRNFGNSFSRFSGMSMIRGLSRTASTPIVAKEAPKDMTKDGPATKVADGGDLASVRTLITQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV73</accession>
    <name>A0AAD8UV73_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_749936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367699.1">
        <property type="nucleotide sequence ID" value="XM_060513845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV73"/>
    <dbReference type="GeneID" id="85397743"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154666" evidence="1">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="8975" checksum="C9B9ECCF8CE91B64" modified="2024-05-29" version="1">MQFSTIFLTVTALAVGNAFAATVPRNFIDGKGSALFGNAGTACSVGAKDGECDQFGRCVQFIPPNEQSILNQGKNVATCTAGGQTGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXS2</accession>
    <name>A0AAD8UXS2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_570025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368615.1">
        <property type="nucleotide sequence ID" value="XM_060504258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXS2"/>
    <dbReference type="GeneID" id="85388157"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23464" checksum="8B9DAE8A3233A533" modified="2024-05-29" version="1" fragment="single">LHEVVDSPRLGLPFGGKYKMTEEEQEDIQLLGKEVLENNRFADDNQCGNCGHFGHWLGDCAFPDDQGTIMGCPLCNTTLHFWDQCLKKNSLTATQQLQLMLLRRRRKPMIRSSTSLRDLLADAIQEGMESLLDSEGLPWTQSYTMKLIKKRRDQPWLKYGPDETNKFPEDPDTEGNVREVMNSSIAENECHRPRAVIQQKKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X794</accession>
    <name>A0AAD8X794_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_595994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000351">
        <property type="protein sequence ID" value="KAK1701625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357025.1">
        <property type="nucleotide sequence ID" value="XM_060506839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X794"/>
    <dbReference type="GeneID" id="85390738"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1701625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="175" mass="19762" checksum="8D75E670758903CA" modified="2024-05-29" version="1" fragment="single">DAAANGTWLELTRAADYLLKCVVPGLLDPLQTGLNPIKPRLLHGDLWAGNIGTDKDTDEIMFLDVGCFYGHNELDLGMWRRYGSQNLGQQYLDEYKQIFPPSEPQAGFDDRNRLYSIKFDLNASAGTPSEKNRNTALNNMLYLIEKLSMILVEGLPRYDPRKDPSAGSEYIYANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8I2</accession>
    <name>A0AAD8X8I2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_593474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000218">
        <property type="protein sequence ID" value="KAK1706952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357952.1">
        <property type="nucleotide sequence ID" value="XM_060506629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8I2"/>
    <dbReference type="GeneID" id="85390528"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="2">
        <location>
            <begin position="203"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="396" mass="42140" checksum="9BEA13F41818C2DF" modified="2024-05-29" version="1">MTLTTEPKPSQAPSQTHEAEADTHSLHSTPSSSSSARSTISRRLSLTRTLSSLHRTRTNTTTNTVRAPPAVKPPNKGFGANLHKITTTAGIPFNKAANLVGAEGWFPQTMPRECAKAARILHAFTDLGPEPPKTQGPLHPLGITRRSMVTIPHQVLAHCAGLAIFNTLRAGAYMGSLAAGSGIVVARRPDGTWSPPSSFVVSTLGAGFMFGLDIYDCVLVLNTAAQVAAFTHPRVSLGTEASVAIGPVGTGGAVEAAVSKTARPMYSYMKSRGLWAGVQIDGTIILARQDCNSVAYADRRISAKKILQTQAEWPEGSMPLWQTLMALEGRYSMDPAIAREVAMMGPPGDATPPPPMEDDDVPAPAYTPSEGITNAPKDVEEEPVLDEKERLRRAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8K0</accession>
    <name>A0AAD8X8K0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_592260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358434.1">
        <property type="nucleotide sequence ID" value="XM_060506518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8K0"/>
    <dbReference type="GeneID" id="85390417"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042262738" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="2">
        <location>
            <begin position="29"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="185" mass="20530" checksum="03327026ADAA9E45" modified="2024-05-29" version="1">MPNVPTVLTFWLALGTGINLTSAAAPAHAGFHVQYPWSSRGANLPSRPELDEFHPFCREIVHNPQAYARSSRTFLSFSGHPGDLVTALYTRNRVPKKRDDFPHVIVQDLPIQPSGQVCVNVTIPFETKLNEMGVMYFEAKDPATGKVQYFCTDVKMADTEALPEEHPAMCAAGNETLIPMPDEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9T9</accession>
    <name>A0AAD8X9T9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Norsolorinic acid reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_710015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359467.1">
        <property type="nucleotide sequence ID" value="XM_060511581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9T9"/>
    <dbReference type="GeneID" id="85395479"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1712610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="376" mass="42213" checksum="BE8F9C526DAB527E" modified="2024-05-29" version="1">MSYLRPAPPPKSALGRYRLLSPTASVRVSPLCLGTMNFGDAWKDWMGECDQSQSEKMLDYFYDQGGNFVDTANGYQGEQSEQWIGEWMMKRGNRDQIVLATKYTACFRRGHDDETLVNFAGNGAKSLHTSINASLRKLQTDYIDLLYVHWWEFSTSIPELMQSLNKLVSTGKVLYLGISDTPAWVVTKANQYARDHGLAQFSVYQGRWSAAHRDLERDIVHMCRDEDMAIAPWGSLGGGNFKTEEQRKASTGRKIPPNETEINISEVLERIAIRKNTLITSVAQAYVTHKAPFVFPIVGGRSVDHLKANIEALSLKLTDEDMQEIDNVAKLDLGFPLNMLWGDKVPDHPGKVFMLFQAGTYDHVPLAKPIAPAHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA17</accession>
    <name>A0AAD8XA17_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_725267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000352">
        <property type="protein sequence ID" value="KAK1701617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357024.1">
        <property type="nucleotide sequence ID" value="XM_060512731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA17"/>
    <dbReference type="GeneID" id="85396629"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="6">
        <location>
            <begin position="245"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1701617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="595" mass="66781" checksum="4F314841BF2AEECA" modified="2024-05-29" version="1">MDDTVERPSDATESYSSTRDRTLGTIFPLTPSSSNVLAPSLGVHVPTNEAPLTNPLAFHTIDWVPGPSGTPVFMGTSSNWAFNRRVLSMTHEAITGTALSPENLFFDGKVYDLSSLGEDFSLANLPTQDFAIYLLNSVKFHCCRLFYLFEENAFMEHFATFHASAADQLKVPRLWFVHYLILLAFGKAFIVQTSKSHQPPGAELFVQAMKLMPDFTFFECDYIERIQVLCCTSLYLHCISSWPAAYRYVAFEHGLHTEMQSHHLDETYVQKCRLVWWTIYVLERQMSALMGVPMFISDECVCTPFPIYYEQAQRTSALHVQIKLAQVLGQIHQTVYGIEGQLDSRYLGATKAVLQSIAGLATNLHDSFDIDSSENTSGVSRVSAHLHLQYHQCIVLTTRPLLFIFLQSKLGQSEPVLMQWLHSDSIRNLLQVCTDSSRQIVKILSRLLSHGLLESFLTFDLDATSTAAVAMSMAAAVEPTLISDHAAWSQRVFLILEEMDSHGSKIAEMISSELRQLDHYLHHLSADEEVPPQVHRTERTISTNDVGSYPTDQALGLEFEQSLAMEAELSTDLLIDIANSLDPESMSWDFPVTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA71</accession>
    <name>A0AAD8XA71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_680542</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360249.1">
        <property type="nucleotide sequence ID" value="XM_060511201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA71"/>
    <dbReference type="GeneID" id="85395100"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1715450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="37268" checksum="7EA3140D28762609" modified="2024-05-29" version="1">MDASKWFEWTTFDIIGDLAFGESFGCLQNSASHPWVDSFFASMKIIPWIQAISDFPLFSVLKPLYFLLFVPKDVLKQRHLSQVMAEENLKKRLAIGGDRPDFVQALLKSGEKLEMSPMEMRDNMVLLTTAGSETTATTLAATTYFLGNHPEVLAKLNAEVRSAFKSEQDIDVNSVQSLPYMLAVLKESMRVYPAVAIALLRQTPPSGAQIAGDWVTGGTTLGIWQYAAYHDPTKFLYPDAFIPERWLDDKRFDGDQKNLHQPFSYGPRNCLGMNLAFAEMRLILARIIWNFDLELAPESKSWADGQKVFFFWDKPPLWVYFKPRQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAT4</accession>
    <name>A0AAD8XAT4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_633921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360879.1">
        <property type="nucleotide sequence ID" value="XM_060509060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAT4"/>
    <dbReference type="GeneID" id="85392959"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1717392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="110" mass="12150" checksum="A61453E357DA191F" modified="2024-05-29" version="1">MLYQVLLYKLIWSSKPFTMFPSLFSSLAVLTTVVLTAQAAPMPASCRATSSTLAGIGMCFEPSVGCNPGQRFGEYIARNIRHEKGIRGIVHLLYEVRCLSGGRQYCLMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAZ4</accession>
    <name>A0AAD8XAZ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase/transpeptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_643149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000217">
        <property type="protein sequence ID" value="KAK1707120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357968.1">
        <property type="nucleotide sequence ID" value="XM_060509654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAZ4"/>
    <dbReference type="GeneID" id="85393553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="25"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="389" mass="42549" checksum="CBDFD10E70D3D075" modified="2024-05-29" version="1">MADLVEGTCEPTFNRVRGLLGKRISEGAEVGASIVVNIDVQNVVDIWGGYYDESRTRRWERDTIVNVFSTTKTITSLAAHVLIDRGIINPYEKVATYWPEFAANSKQDIEIRHIISHTSGVAGWDQPVSLAEICNFDRAVSLLAAQAPWWTPGTASGYHSFIHGFLIGQVMRKVTGKTLKDFIRDEISGPLGADFQLGVAESELHRVSDLIPWAVPPSNSSNSTYTPSPDSISARVMGNPAFSPEMANTALWRNAEIGSANGHGNARSIARILSAISLGGHVDGKQFLKPETIDLIFHQMSNGTDLVTNMPTRFGIGFGLTGEGVMPTWLPQGRICFWTGLGGSVAIMDLDMKMTIVYVMNKLYHVGQGSDLTVEYVKEIYRAVEASRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBM6</accession>
    <name>A0AAD8XBM6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_584650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361764.1">
        <property type="nucleotide sequence ID" value="XM_060505779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBM6"/>
    <dbReference type="GeneID" id="85389678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="37758" checksum="7EC707F586488226" modified="2024-05-29" version="1">MASPYTVLVTGSAGHLGAALMLSLPTLGYVPFGIDILPSATTTTVGSITDRALIASILADNPSITHIVHAATLHKPHVDSHPKSAFIDTNITGTLVLLEEAAAHKDRIKSFLFISTTSTFGRALAPAPGQPAAWITESVTPLPKNIYGVTKCAAEDLCSLIHRQTSLPVLVLRTSRFFPEPDDDEDRRAAMPGDANLKVCELAYRRVDIADVVSAVVCGMERAEKIGFGKYIISAPPPFATAAADNDDEAAAARLTLLRRLDSDAGAVVAEVVPGCAAVFEKLGWRFLDRLDRVYDSSKAVRELGWRPQWTMEKVVERLARGEDWRSELTHAVGKKGYHAVSTGVYTTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCL4</accession>
    <name>A0AAD8XCL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DszA family xenobiotic compound monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_745019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358885.1">
        <property type="nucleotide sequence ID" value="XM_060513178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCL4"/>
    <dbReference type="GeneID" id="85397076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF30">
        <property type="entry name" value="XENOBIOTIC COMPOUND MONOOXYGENASE, DSZA FAMILY (AFU_ORTHOLOGUE AFUA_6G01920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="2">
        <location>
            <begin position="43"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="54384" checksum="09081F6CC6555B64" modified="2024-05-29" version="1">MAFSKSQDGGTSAKSQKQILLNAFDMFTVGHLSFGQWRNPKDRAKDKRRDLSYWTDLAKLLDKGGFMGLFLADTFGPYDTYKGSAEPSVRTGAQWPMADPVIPVSAMAAVTKNLGFAITTSTSYEQAYVVAKRFSTLDHLTKGRFGWNIVTSWKESASKAVGLPLVEHDTRYSNADEYLRVLYKLWEGSWSDTALVEDAEKGIYSDYSQIRPIHHHGKFHVDAPFLTDPSPQRTPVLFQAGTSPAGIKFGSTHAEGIFVAGLSPHVVAPRVKAIRDGAIAAGRDPYSVKVFAMITPIIGKDEEDAKQKYEEALKYVLIEGGLAQFSATTGIDVSQFDLDHELTEADVASHLQRIHSSLYNLRYRGDDVPKLTPRNLGTVTAIGGNGAMPVGTAAQVADIFQEWVDIADVDGFNIGYVVTPGSFEDAVEYLVPELRSRGLLPPAIPEDEPAPTFREQIYGHGQKGLRSDHPGFKYKYDTYEETVAKEDAAKVATAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCW2</accession>
    <name>A0AAD8XCW2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_636227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360098.1">
        <property type="nucleotide sequence ID" value="XM_060509240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCW2"/>
    <dbReference type="GeneID" id="85393139"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="11918" checksum="C396C1473486FA85" modified="2024-05-29" version="1">MTRYLLIVSQLWKSPTWNDSSAQMSYSIRPPCASSPLEYPFDSPLATLSCLKILYRPSSVSSPTCRLPASFSSFLLVYASPRRFHVPPSPSEDITSKRGENPSATAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDD0</accession>
    <name>A0AAD8XDD0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_436784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362171.1">
        <property type="nucleotide sequence ID" value="XM_060503077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDD0"/>
    <dbReference type="GeneID" id="85386976"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="28671" checksum="FC7B683EDA26ED79" modified="2024-05-29" version="1">MALGVYSPVLFPCLVHKGVKYCCVISRTNIGEGEQNKTPAAVLPISRSPVPFFSPLVPLAWPLCVLFPTKAAPPRMSSSKDHFSSKSTHNRDKGMLKRQQKSSIVTKRSSRQPTWRGRGSSGSGIAPFQARPPSTSGRRLQRAQQGLKEKWFDGVRVTELGALRPDPAAALAMVVRWWPLVGWQLFLREMMRTGRVQMGEALVTLSKVLTLGHDHFPLMSYIVISTTVARLKTLDRRVCLELFYDGIEALTKRSPMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDU1</accession>
    <name>A0AAD8XDU1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_674004</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363547.1">
        <property type="nucleotide sequence ID" value="XM_060511143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDU1"/>
    <dbReference type="GeneID" id="85395042"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF199">
        <property type="entry name" value="MFS EFFLUX TRANSPORTER INPD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042253958" evidence="7">
        <location>
            <begin position="17"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="486" mass="52146" checksum="91C8F8A077DFB68C" modified="2024-05-29" version="1">MAVFLVFLDMTLIATAIPAITNQFNSLQHVGWYGSAYMLSLCSFQLVYGKCFELFSLKWTFMVAIAFREIGLAVCGSAPNSIAFIVGRAITGIGCSGIIIGAWVVLAHSVPIRQRAVYTGFLGAFSGVGGIIGPLISGALTDSHLSWRWAFYVSIPIGVATLALIFFCFRPPQQPDQGEPRTLKQKLMEFDILGLLIFFACMICLLLALQWGGSQFAWNSAPMIGLLVAFGVLLISFIGVEIWKGDNAALPPRLMKMRNIAFACFYAACIDAAYYTADIWLPIWFQAIKGESARESGIKLVPYVGGEVLAALTAGYLVTYTGWYNPFMLVATVLGSLGLGLMTTFELDTGPSKWVTFPVIAGVGIGLGSQQPMMGVQSTLALSDIPAGTAAVTLFQNLGPAILMSVANTVFANGLTKHLHGTGGLNGQTIADMGATNLKDMIPMDLLPVVIEAYNKALKETFTVPMAVAVISIIGVIGMKWEKLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFB2</accession>
    <name>A0AAD8XFB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_720091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364196.1">
        <property type="nucleotide sequence ID" value="XM_060512246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFB2"/>
    <dbReference type="GeneID" id="85396144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046464">
        <property type="term" value="P:acylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="34"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="333" mass="37555" checksum="4DC041A3205A5957" modified="2024-05-29" version="1">MAALDLSTMVKKTLDVSRGFTYTYYTSPARDSKPTLLLFHGWPDTARLWAGLTNNHLIPNGYGVVALDNLGFGDTSRPTDPEDYAWHRLAADAVEILDRERLTKVISLGHDWGCLIAQRLYNFHPDRICGLVMLNVPYMPPTGNFDLEAVNQVTRKIFGVGIFEYWHFFLAEDSVDLMNQNLESVYSVTFGDPQTWLENWCTTGKMREFITGGRTQPTLPFATPGHRADFMERYGRDGFAAPRCVYTVTGSGIQDKSERMLSGEVKTVRVPVLYWGGEQDYVCRPELLQQSIAAGVLPDVKKITREGGHWAFLEKPAVFGQDVLGWLHQSFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFE0</accession>
    <name>A0AAD8XFE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RIC1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_618527</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365859.1">
        <property type="nucleotide sequence ID" value="XM_060508078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFE0"/>
    <dbReference type="GeneID" id="85391977"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034066">
        <property type="term" value="C:Ric1-Rgp1 guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009771">
        <property type="entry name" value="RIC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07064">
        <property type="entry name" value="RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIC1 C-terminal alpha solenoid region" evidence="4">
        <location>
            <begin position="854"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1059"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1068"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1080" mass="119922" checksum="066ABD8CE929995A" modified="2024-05-29" version="1">MYWPIGTPRIFATNSRSGPAFNLVVSHDGLPNPFDNRPTDEASESPFGNVQQQQSPHDTLELATPMTPLTPGIQPVDDQDHDPETSRPSPRLNVNIPLKDPVLALRISRPGHLFASITSTSMTIWQAKPTVILAVVVRSETSLSTYGENVDLLMRPDSAILVVRTTLGYLITYSLAMDSEAQVYKPYFPSYANIQRRRQNHHGQPGSTAPDQYLWGPGEGQGVRDVSVRFRMVIKVDAGIESALALDDELVVATRKPGAIQCIRWTPDQSGSQTKTEIISRMGWLEKKITVVEMTHDRPMNLSTWTTSDGKVYAVQRLHPREEADPKKLFKGYCFHTPAKPEESAIKAVINARFSLIAIGCADGSIRVYSARDYAGNIPPSHTHTIPVSTTVSGLLTTLSYSPDGYCLFAGYESGWATWSVYGKPGSSSFGAHNAIIEANGENWISGIGDAVWLGSGSEILITHRKHEAIWVLEMARSAVVGNYNAANLMRTVLQTSTNVMIYRGYDLPDLASISAEPHLWHTTKVPSAYLLQQWPIRHTVISPDGRYVAVAGRRGLAHYSVNSGRWKTFANEAMENEFQVRGSMCWYQHILVAAVEANKSHELRLYSRETALDNSQVLHTERLPAPAVLVTTSGEDSLLVYTYDNLLYHFIFAPTNGSIRLVQLGQIAFHGIVRSPARVRGLSWILPDSQLVDGDPSQDVAVASVLFLVDAKLVLLQPSFNSEGNLKYDMKVIAQNVEFHVSMRDQPHFDGLATHAEALSPTGADVTLRNSLWVFDGQDFKVWADIQEVLQAASNEAQRELPKTISVPLDFYPLSTLLGKGIILGIEADLIQRRDISFSFFRFAIRTHLFLPDILRFLLTEGRKVDAVKLSDRYQNLEYFAHALEILLHKVLDKEVDSGPSPEEAILPRVLSLLSSFKQYLDIVVQCTRKTEVRQWRTLFAYLPPVQELFEESLQRGSLKTAGGYLIILHTLDELGSASEQTVRLLSRAMKEGDWELCKELARFLAAMDETGDTLREAMEGVNISMQGNKDQSGLMSRLDVPHSKAVNGLGLKYIEQSDEMESEGQSVSSAASFSSDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFF4</accession>
    <name>A0AAD8XFF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rtf2 RING-finger-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the rtf2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362873.1">
        <property type="nucleotide sequence ID" value="XM_060512356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFF4"/>
    <dbReference type="GeneID" id="85396254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006274">
        <property type="term" value="P:DNA replication termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16653">
        <property type="entry name" value="RING-like_Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006735">
        <property type="entry name" value="Rtf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027799">
        <property type="entry name" value="Rtf2_RING-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775">
        <property type="entry name" value="PROTEIN C20ORF43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775:SF0">
        <property type="entry name" value="REPLICATION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30914" checksum="D7EA60FF5C524A18" modified="2024-05-29" version="1">MGNDGGSIPKRRELVKESARALTVSELKANVLESLGHAWSNDPLSNQPLNKENIVSDWRGRLYNYESILQGLMPSDDSTESPPSNPESQELTFASTGIKSLRDIVKLKFHKHTPPGTKKDVWVCPISLKELGPQVKSVYLVPCGHVFAEAAIKEIQESACPECSEEFKSENVVPILPTEERDLRKLVQRMDDLTATGLTHGLKKDKKASGKKKRKAEDDAKEIGNGDKPEKKRATDDAKAAKKESKTSNINNPMAASLTAKVLAEQEELSRRRKMASSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG27</accession>
    <name>A0AAD8XG27_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dopa 4,5-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_650310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366669.1">
        <property type="nucleotide sequence ID" value="XM_060510364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG27"/>
    <dbReference type="GeneID" id="85394263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="21280" checksum="61A13069D0A3AD50" modified="2024-05-29" version="1">MTMVTQSTPPTPQTDLKTVVEARTREWHFHIYFLLQSPTETAAALALRDAVLRLRRDGAFVAVPLFRVNEFPIGPHPAGSYEIWVPDSSFSDVFFYLAANRGNLSVLVHPLTSSQRRDHETRNAWMGTPWPIYLDSLPSDGDVPLQYPELGLGWSTSPEQEISLEERLRRGAKVEALLADDPEAAPAPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG53</accession>
    <name>A0AAD8XG53_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DSBA-like thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_276016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366067.1">
        <property type="nucleotide sequence ID" value="XM_060502095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG53"/>
    <dbReference type="GeneID" id="85385994"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03024">
        <property type="entry name" value="DsbA_FrnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13887:SF41">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="218" mass="23770" checksum="7242D966C3D61352" modified="2024-05-29" version="1">MTVIKIEAVTDLLCPWCYVGKRNLDRAISQYRAVDPTAEFEVVWKPFYLSPALKSTGYDKREMYTTRFSLAGDLPAVLSRITTACAQTGIALNVTGRTGNSRQSHKLLRLALVTRGPAAQDALLEALFRGHFELGADISDRAYLVKTAAEAAGLDESDVEAALDSDRAGEVVDEEVVGARKAGVTGVPTFTVQGRWRVGGNQEPDVFLRVFERVTEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGT9</accession>
    <name>A0AAD8XGT9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_618315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365816.1">
        <property type="nucleotide sequence ID" value="XM_060508071.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85391970"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000022">
        <property type="entry name" value="Phosphatidylinositol 4-kinase stt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1612"/>
            <end position="1907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1923" mass="214060" checksum="57E49875D160FAA1" modified="2024-05-29" version="1">MTRDIRQRALEKIASLSAASSRTSFDRSDLDRLCKATQAAGKGVNGYSGKQNLSSLGRCPMTIREFEVLLSLCKAAPAIQTSQSAQKLAHQLIPYILEAHVQVFVPSPFFRKVEPSPTEALAFHITAALLSLGSHYDDLYEMISDNIWAFVNACDHAVDHTVPPQADDEDPNLEDAIRTATIAVSLLGFLDAASAQADFWRAGGRLALVQRFRDILSESFLVAVETAFSTIRNSQSSDRHAREWKRYLRHYSAAGRPLGAILLQRSYMWLLVSGTSLLVTDASLLRGTHILDLLMSGDGAFRPGSPRSPDADYRSLDMYTTVAVDQMNYLEAGEDYLKLGSSWQQRLAFAVKSAALISYLNCSLMNEDVADVDVLINWLEETLADPLEMADENLAATVLRSIALVCKISRGYAATASRLLPRFIVQSAPNARTVAVASKSLAFVLQLLSHDAVITTLYTLGNVLSPGSDRSMTNGTNGDLAVDAAATLYPNRHSTGSSISLAITGEEETAMVYGNVVQAICGIATACNDEKITALAQSMLLQKIDKVNSSVDAQIVSGAAALALKGGQLEFRSLLKVFSRICHIGVVGHKDFLLVAVMKARTYISANLHRGSPLYDIYWEHLLESIISMGDVHQSNHTKEADVQLAAREIAELLHPLAVFMSTNDLAFNTITDDESHSMIRDAWFNIVVHGFTTQTDMGKTYLNELRIMAVHSPPLVAEQRGEQIESDIELNTVLRRGMSSDRESLQKRHLTELIPNKATEIKGLSYRKVIFLHAAYLVESLRADAGDCTKALSYFLEPSMRRGEVSSTMEGIAAAVVDKYLRKTLGGTDATFSAQYAAAQLVAIFCGCCHRIERVQQAAFTCADRIITQVPSALCHRSSLFALLELLSLMWSSCLEAETDLYAPRSKFTSSLGDVSVELSDDYTFRRHTLDVLNRRAKQWVSSVISIAPLDIKGLLQTYLSEFDDEGAYGHISLGRSFAIELGSLMPSTDQRLQSLDRVGECSINTGSDFVAQYTTRQEYRYGETLPERGNELVNFMQLNRRASFLQSSGSSASDSANAATALAHVEARIKSKKTTALNEVRDILRRAAALLCRSNRDESAVAHYLVSIPFAMFTKQSIKLGVSLWLGVMNENPHLEPRLLTEIAQQWEATIQSGLGLFSHAMSHPDPFFLKEEFAPSDLEALAKRKQQVHNLLSPHMRLLQFFASHFNATRLGSPDVQRVFLRMLDVTLDAVRSSTPHPMARELRFQIVLFGLKVLHVCTTIGAIAQWRFKEKILSAALSWFRYAPRWSFGSNILQLKTELRLLTDIVAALKHVAFIGANAADTIKSLQAKEQLLVFLLESEQTRLSVWVHPLGEPTKAHGQANKAAIETALAPLIRVAWAEDPSIAVELVTRFPYPRVQREVRWLLINFPQKAISEPEGLPILLGGSLPNDVSFQLKYLLFWSPVNPITAATYFLPAYRNHPFLIQYAMRAMESHSSDTLRYDALGYVERYILETAQFSQLFAHQIIWNMKANAYKDDDATIPDAIKPTLDKVMEKMVASFSDVDRTFYEREFAFFDEVTDISGKLKPYVGRPKPEKAQKIEEELRKIKVEIGVYLPSNPDGVVIGIDRKSGKPLQSHAKAPYMATFRIKKNKGSLEDVNDMLEDVHKKDSPPAQENTIEVWQSAIFKVGDDCRQDVLALQMIAAFRGIFHNVGLDVYVNPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYDYFISKYGNEDSLRFQQARSNFVKSMAAYSIISFLLQFKDRHNGNIMIDDAGHILHIDFGFCFDIAPGGIKFERAPFKLTTEMLAVMGGSPHHQAFKWFEELCVKAFLASRQHCEKLSQIVLLMMDSGLPCFKPESVQHFKERFVLERSEREAADFVKDLIRRSANSYSTGVYDQFQLLTNGIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHE4</accession>
    <name>A0AAD8XHE4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">endo-polygalacturonase</fullName>
            <ecNumber evidence="3">3.2.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Pectinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_650546</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Involved in maceration and soft-rotting of plant tissue. Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366431.1">
        <property type="nucleotide sequence ID" value="XM_060510385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHE4"/>
    <dbReference type="GeneID" id="85394284"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000002">
        <property type="entry name" value="Endopolygalacturonase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF9">
        <property type="entry name" value="ENDOPOLYGALACTURONASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 17 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 18" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255993" description="endo-polygalacturonase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00083621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1726376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="388" mass="40028" checksum="48B57EDBE11012E2" modified="2024-05-29" version="1">MAKFFAPAAALLNVVLVAASPRGHHGSHIRYTNTIPRASNATGCVVTKYDDIANAVKTCTDITLSNIAAPSNGAIDLSKLQTGTKVTFDGTTTFADTVDSSFDPIIISGTNIVVTGAPGHVIEGNGAAYWDGLGSNGGGDKPNHFVVVKKTTNAKITNLNIKNWPVHCFSMTGNQGLTVSGLVLDNSAGDAPNSKSGSKAAAHNSDGFDISSSDNVLLENIKVHNQDDCVAVTSGTKITVNNLYCYGGHGLSIGSIGGKSNNTVDGVVFSNSQVVKSSNGCRIKSNSDTTGEVSNVTYKNITLTDIDTYGIDVQQDYLNGGPTGSPTNGVKISGIHFIDVTGTATSDAYNYYILCGDGSCSDITFENTKITGGGKTSSCNFPASGCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG3</accession>
    <name>A0AAD8XHG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_626038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363535.1">
        <property type="nucleotide sequence ID" value="XM_060508533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG3"/>
    <dbReference type="GeneID" id="85392432"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="34600" checksum="2A3793DEE1341573" modified="2024-05-29" version="1">MDSDIGAAAFAALTSTSIYETGMTFTKKEHKETYPTIFPSRPELSQAGRTVLITGGSAGIGFAIAKGFAQAHAKRIIILGRRQNLVDEAVSELKKEFPEVRFDGYSSDVDDLADVEKLWKGFEADGTVIDVLVLNAAKISEHGPILSLGRDDVWSSFTMNVRSLLDLSERFYKQKDGEGRQKFLVNVSTEASHNFTKSGPWPAYSASKNAGTMLIQMIAKDTPPERMQVINFHPGVVHTSAFKSAGIPEDVYPFDHVDLAGNFAVWAASEEARFLHGRFVWAKWDIDELKSGVIGEKIKNNDHYLKVGVVGLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHV2</accession>
    <name>A0AAD8XHV2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_231256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366986.1">
        <property type="nucleotide sequence ID" value="XM_060501808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85385707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000311">
        <property type="entry name" value="GTP binding protein (Bud4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012966">
        <property type="entry name" value="AHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08174">
        <property type="entry name" value="Anillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="1302"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="965"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1157"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="685"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="812"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="836"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="969"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="981"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1471" mass="163832" checksum="8203AAE4A797CCF2" modified="2024-05-29" version="1">MASSEDPVHPLRISKGSSTPGSPPPTKASTGIPRPLSELSPSDLRRNSPSFKQPSKKMTLNTDSSPFQSSPLETTTSPRLFWQKRNLDSISTENSGLYGGARHGSPSPTRRTSIERLQRASRVKNSNILALEQKQEYDPTRVPQIERPLAKHSGPSYDGTTTIINGLRSSDSLNRGIGHQRNNSSRSSIPIFSPTTSPTKGSTPMQINPSNPPRSPGKDQGSPIKSSLSRSNFKSSFDPETGTWSADTSFDDRELPSGKSLHRHAKSVTFDAAPPQINEYEMATPDISSIGSNSREGSFDSMDDEDDEDGHYHFGDHDMEGDSFDASLEDTDKTPVVGPDDWRQSAERMEDPFGGSPMPDALPPRVGRTEHTRSDSSTSDHRPLPPLPGMGSPARGSPAFSDSRSSPGLSATAERMVGAHRSLPPPPPAAASKNEIQSIGNGKMTLEERLKLMMLSDDHKSANEQQRERRLRRGAQRDRIQSPASDTETAESSMLSADADEADDTIGDISALEDYELPSRISRESIMRRVNGGANDQGGDYFSSPAPSSSPERPSPERRLPLPLDPDVPIPSTEDSILDDISELSDEGSVIIHRDETSDADTESITDFYARSDIDENDADSASHYSDGPARQPEVTQVDEDILTPRAASPFQSFDLASEIRPLELKSDKGFSSPDQRAVSPVDLPVRELTPETKAEEFIEPTSEPQDEVIEQPQPEPEAEKEPSPEMQVDAPVDTASERKHSLPDFHDEGRDNEFSKGLQSFMLPPPPEPSAEEVEELQPPPKMTELQAEMQRPVTPKHLSKPDYDGSGWGDPEDEECEEEPGTPESVIHRPMSDSESEIFDELPMESPAIPERQATIKASGSKLKTRPSNTPSDIIAMREARRQVSREVPDIPAIPERHRNRLSRDLQGEPTIHDDEEFVDRRSSFKKRSLTLDLDFGLSLDQDFDRVIEQQKRGYLMRQNTKVVTASDKESSDMWKTRSAGNSPVKTDRPQSWTVEPWNGRPRQKSIRRRANTSGPVPPMPGQESNAQTLNPLAEEDLNPELATEESGERGRLFVKVLGVKDLDLPIPRTERTWFSLTLDNGVHCVTTAWLELARNAPVGQEFELVVPNDLEFQLTLNVKLEKPAPAKKVIVQSPTKTSKPKTSTFSRVFASPKKRKEMEMRQREEEERVAAEQQKAAQARQMKVAPTAWDLLSPLAAEDGSFARSYVCLKEHESRCYGRPYVVDVACFNEWATEEATFASSVKSKRGNTAVVRRAPYKIGKLELQLLFVPRPKGSTEEDMPKSMNSCIRELKAAEERLAKNWEGHLSQQGGDCPYWRRRYFKLVGQKLTAYHEATRQPRATINLANAKRLIDDRRALTERETTGKGGRRRRSAFAEEEEGYMFVEEGFRIRFNNGETIDFYADTAEDKQGWLLALTDLIGTGRGDSEDDVGGSRKQGKWCDLILKREEALRRRQEGRRVHSRTKSTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIU5</accession>
    <name>A0AAD8XIU5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_316553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365095.1">
        <property type="nucleotide sequence ID" value="XM_060502339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIU5"/>
    <dbReference type="GeneID" id="85386238"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="124" mass="13897" checksum="12E6FF97E9FE0A03" modified="2024-05-29" version="1">MVVRSPLWIWHLGVAPCRHFTALSLVFLFLFPLSKTSASRRGGWSRPITHTHTRTNKHTTTTTTTTACLSPQISDAGAFQYDVSVCLLFCRNLHIFSEHYFSDHPSLGGPFFLCAQLGPLTIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIY4</accession>
    <name>A0AAD8XIY4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_576866</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365290.1">
        <property type="nucleotide sequence ID" value="XM_060504961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIY4"/>
    <dbReference type="GeneID" id="85388860"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF26">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="309"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="199"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="921" mass="102158" checksum="5CEEC37F42536FF3" modified="2024-05-29" version="1">MTSTQEGETTEEERLKVEDLQESKLEDDSRMHEVGLQEDRLQEDDIQVDGMNDDRIQEETLHDARRLEHERLESERLESERMDEERIPSYPSPLPEERLQEADRMHSYPSPSAEAQDSGPYYHPATRDDDPQEQQQPPPTPQQPSSHSASVEELQLAAQLGQDLAAEPLMHVTDPGMNVEDPSLRSIMPNPHSNSHSEQPQSQQQQAQAQAPTSAQTQTQTQTQTQAQAQTQAQQHQHQHPPHQHPHQHPHQPPPLPPASRSYVSEEALPESLQQHMPMSMPMDHHHLAQPYALGDSTPPRKRSKVSRACDECRRKKVKCDAQSDAGDSPCSNCKRSGIRCMFSRVPQKRGPSKGYIKELADRINSIEGKLEIQSESLPPESMVNWTSAAAMLNSMSGPGEDNSRKRPFSSISSTDISTPAPQRQVAWGTEPRPLQPIATPSDRYQPSPFATNGLAPQPLALPIKNDMQPRPPIASMDGPVADMPDIDQARDVDEEVFNGYLTMIHPYFPFLPSSRVLIQEYLAQCPGLLREAFVEALSGTIHSFPSFQSGTPGDVRLAHTLLVEWEASDSTSRTAVANLVFLQTLLLMIIEADIRPLGSIGAPKESLLGRAVASANTLKLYQAKADLSEAEAGPDNESHLRVRIWWSLVLLDRWNAVGAAVPSLIRDESVVLAPGLKAVIGEVPYLLIRASKFLSRASSMITNFQEPLNTTFADRMVGSFMDAWVEDFREDLPAHIEPNIYPVVHLVYWHCRLLAYLLNPSAKSTDVLWPSQELINLLIGHSQLITPLHHHFTVLAVLTLVELAKLDKTKEEATRLLGEFRDSSLPASVFDGLVRDRIADHLRLSTNTAAAPGPSAMEAAASQGLQHLADLATLSSAAVEKTEEAPTYRTAPSYEDMGFDPRPLLLIGYLNVVRATQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ69</accession>
    <name>A0AAD8XJ69_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Casein kinase II subunit beta</fullName>
            <shortName evidence="4">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_575879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer composed of two alpha chains, one beta chain and one beta' chain.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365860.1">
        <property type="nucleotide sequence ID" value="XM_060504866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ69"/>
    <dbReference type="GeneID" id="85388765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000003">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF39">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00062110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="30212" checksum="5E10327DBD426F4E" modified="2024-05-29" version="1">MMDDFVSESDSDYTSYWRDWFISSRGNEYFCEIDEDYLTDRFNLTGLNTEVQYYQYALDLITDVFDLDCDDEMRETIEKSARHLYGLVHARFIVTTRGLAKMLEKYKKADFGKCPRVMCHSHPLLPMGLADIPNLKPVKLYCARCEDIYNPKSSRHAAIDGAYFGTSFHNIIFQAYPALIPTKSAERYIPRVYGFKVHAPAALIRWQHQKKDAMRRRLRKMEVDSGFRDEDLLEDDDDDVEFEGTEARVRAGDDEGVAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLU0</accession>
    <name>A0AAD8XLU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_759968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369833.1">
        <property type="nucleotide sequence ID" value="XM_060515158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLU0"/>
    <dbReference type="GeneID" id="85399056"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="370" mass="41229" checksum="FBBEE9B9B1481AD1" modified="2024-05-29" version="1">MASTESSEPQVSSPVRAAKSPRAKGSSPPAATSSPAGNANETEAGQIVALCIHTSSTASLTESITEYRRILGRTYTQKVDYWGPNDEKQNEGLDLAHYWECVFFDDKLFLAPIGDSPQKVLDIGTGTGIWAIDFADEFPSAEVTGVDISPIQPSWVPPNCKFQIDDIEADWTWPTEFFDYIHIRHLEGCVSDWPKLYSQAFEHLIPGGYVEVNELDLEDYSQALGDDLPQDHVYRRWAKIMFESMDKLGKTGKQTRDHGIANGMRNAGFVDIVEKSWPIPIGGWASDPKLKEVGAVNLQYIDQSLEGFGTFLLRQMMGWEDVEILVFISEMRKALRDLKLQTYFTLHVVYGRKPEQSDEQAPVASAAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMK4</accession>
    <name>A0AAD8XMK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Translocase SEC61 complex gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_603051</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370154.1">
        <property type="nucleotide sequence ID" value="XM_060507206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMK4"/>
    <dbReference type="GeneID" id="85391105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12309">
        <property type="entry name" value="SEC61 GAMMA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01067">
        <property type="entry name" value="SECE_SEC61G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="70" mass="7688" checksum="23E00F702EA9DC82" modified="2024-05-29" version="1">MADQVKEILEVPSEFAQEGVQFMRRCTKPDKLEFLKLCQAVGVGFLIMGAVGYIVKLIHIPLNNILVGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN77</accession>
    <name>A0AAD8XN77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_373037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370540.1">
        <property type="nucleotide sequence ID" value="XM_060502653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN77"/>
    <dbReference type="GeneID" id="85386552"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8230" checksum="EAEA118C3E617A73" modified="2024-05-29" version="1">MLRDYLGPVPASDQRRLASYSSSPDSRRLLGPLTTSHSSTRARERVSARGHSNQGDTNQYPTKLIISEATVAPSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN83</accession>
    <name>A0AAD8XN83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alkaline-phosphatase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_601216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370514.1">
        <property type="nucleotide sequence ID" value="XM_060507084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN83"/>
    <dbReference type="GeneID" id="85390983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16142">
        <property type="entry name" value="ARS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF42">
        <property type="entry name" value="ARYLSULFATASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="7">
        <location>
            <begin position="8"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="460" mass="52000" checksum="BC0F9A7363D97C17" modified="2024-05-29" version="1">MSRDPNRPNVVLILADNLGWGELGCYGGGALRGAATPRIDKLATQGLLLHNFNVESDCVPTRSALMTGRHPIRTGCRQSVPAGFPQGLTPWERTLAECLKENDYATAHHGKWHLGDVPGRYPSDRGFDEWFGIPRTTDETQFTSAIGYTPEVAEMPYIMKGAAGQESENVRVYDLEARRLIDEMLVEKSKDWLSRQVAAERPFFLYHPLVHLHFPTLPHKDFAGTTKQGDFADSMAEMDHRVGQLLDHIDALGIRENSVVIFASDNGPEFREPYRGTAGPWSGTYHTAMEGSLRVPFIIRWPGHVPESVTSNEIVHITDIFTTVLSITKSGVPDDRPIDGIDQTTFFQDPTNVKSERLGFLFYIKEELRAIKWKDWKLHLVWEPKVNQSSGRLESPYLFNTVRDPKEESDILSFNTWVLQPMTKLRTEFQRSLANDPAPPDPLKDFLCSNISNIDVKILW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPR6</accession>
    <name>A0AAD8XPR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_598679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371339.1">
        <property type="nucleotide sequence ID" value="XM_060506964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPR6"/>
    <dbReference type="GeneID" id="85390863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd07609">
        <property type="entry name" value="BAR_SIP3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13280">
        <property type="entry name" value="PH_SIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000079">
        <property type="entry name" value="Transcription factor SipA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039463">
        <property type="entry name" value="Sip3/Lam1_BAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042067">
        <property type="entry name" value="Sip3_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="313"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="934"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="669"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="879"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1258" mass="139210" checksum="88A14932078087DD" modified="2024-05-29" version="1">MAEPAASVALAAAAATTAQKQTSPAIPVGLNEASLDSPTFRSTAQHFGEHIDNVEKWLDDYVRSTSRVTRDILALEESVNTYLSKIFPPAATADAIVDHDYTLLALRRISDGSKEWWTQIMSTVRKMDTISVDPIRSFVAADLRSFKEVRRVLDHTQRNFDQAMARYMSQSKTKEPSAIREEAFAVYETRKAYLKVSMDFCQLAPQIRFSLDKLLVRVSSDFWKEMKRSRDAAAVSTKWGSEMDRIRGWSREMETTEFVFKRELQIARRDIGESTLQAFKPSRELEDYSASTVQYLGSRGPVSVQPQESSAVVSEKQGWLFLKTLYGKPARSNWVRRWYYCREGIFGWLINGPQGVLQGDEIGVLLCNAKPAVAEDRRFCFEVKTKSQTLVLQAETQNQLTEWLEVFEVAKKRAFEASMDRDSASSPAGADPAFSITPPPLPEFSARSMDAIVAGEEPSGSFDRAGTLPVPGSDGTMAGRASFDVNAGAPRRSITALGRDLGREMVREEGESNRDHAARIIQKLDLHRKATFGAGAEAAGAAGGAPGAGGIAGLIASHGHLPGYPSPPQAGSKNSSTSRLPALDPVQGTLAPLTLARPPAATNLSRTAVMLSVDRSIGSDTTSHMPTSVLANYWGSSPWSTVYGSGPGRPRTPGLLEENPFGIVVREVGKPGEEKPPTPTTTGHRKTVSVDAKPSQAHTPFRQPVETFVPGYPPELRIQHLQFRILFPNAPLDEKLVLVFRAAWSSSTGKDSPSHGQGLAGNGRIYITPDNMYFYGQQMGLVVAYAISLDIIAEVTAAPGKECDFIFLHLGEDGNETGYTRITIKIFLDNLQLLHARMNLLIDDLQSEEPMELPELIRALINLEYEDYSKRSPSIESWEEVSSNTPFDDGTHSGRPARRQSQFGPRLRLAGPGSRQTPKVQVPAHPVVFEPEDMQRMVAERHFEISAKACFHVLFGDKSFVFPKLYFERRAQQIAQGPWALADHGRMRREFQFKFDYKDMIGRPKTVDVVDYQTMDVFQEHVTYVVTHTKTAWHLPHSQDFKLVTKVVITHVAKSKCKLAIYTKVEWSKIPTFSKNLVERQALNDAEGDAEELADVATDQVRKLGPHSRTKRAIQVYGNIGQQTQVVVFSPADAAASKKQLIKPRTLTAMLLETLRSFGESAVTSLIMWAIAVVKTFFSVVTAHRLILLVLAVSAFTNIALTSKESSTWWTERRAAKFMTRVGVGPNVMMSKAIYMADLGEATGAVGHNNSWPTDSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ62</accession>
    <name>A0AAD8XQ62_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_248445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371452.1">
        <property type="nucleotide sequence ID" value="XM_060501916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ62"/>
    <dbReference type="GeneID" id="85385815"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="197" mass="21491" checksum="680C7145659EC10A" modified="2024-05-29" version="1">MPPGTASPPTPVPRVAYRHSPKGEEKKETAGFAEISAASVGILPSFLARSIPPLGSLADTTQGPMVSFGIPLITSEIGGRISNYNRPAIASSIMLSTIHSDTKLALTPRNNDSGSRVRSWHSTLVTDRSTFQFCPGKPSESCAGTNPLLHCVRQIAWVTHHFKSIQWKNVPKIEHPNYRNPEYRKPCSATQLCLFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQE1</accession>
    <name>A0AAD8XQE1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_596107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371723.1">
        <property type="nucleotide sequence ID" value="XM_060506846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQE1"/>
    <dbReference type="GeneID" id="85390745"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042096942" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9254" checksum="CC8DF1DE586A743A" modified="2024-05-29" version="1">MKAVYFIKVCLLVISRTICFHAVPTSKQQYSFWVWAKHSNPKRRRYHKFRLGKAKDELSLREVSDASAQAGGRPVQSNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQV4</accession>
    <name>A0AAD8XQV4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_564119</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371752.1">
        <property type="nucleotide sequence ID" value="XM_060503611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQV4"/>
    <dbReference type="GeneID" id="85387510"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045033">
        <property type="term" value="P:peroxisome inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14076">
        <property type="entry name" value="STKc_Kin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000397">
        <property type="entry name" value="Serine/threonine-protein kinase KIN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034674">
        <property type="entry name" value="STK_Kin4/ppk1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="292"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="241"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="679"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="720"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="851"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1033"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1073"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1150"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1167" mass="126476" checksum="25754A088C7D386D" modified="2024-05-29" version="1">MSSAALQPVHHTSALASPPLVAASPSSRQYTSNHSSPSREAYNANLQHNFASPASSQRPPSRPSGNGASVNTEDPTSPMTSRVVPASPVAVAPSSPDYQSSSSEQRRNMPPVAPPRTSSTNYSGATTTTTTTKRRDHAAEKAASSPRRGQADGTNGNVDYTYSDDGSASRSRRSHQQMPPDSPHRSSGNRPGSQPTVIPVRSHAPQTTASPKQPTREASEVLNRMVVSQPEVDIAREKERLAEAQSTRIGSSHDDAAPPPIGMSEHDDGRRGGRSRHDHSGKREKVVRFGDYVLGNTIGEGEFGKVKLGWKNDNNVQVAIKLIKRDSVGNNPSRLAKIYREIAILRGISHPNIVRLHEMVETERHIGIILEYASGGELFDYILNHRYLKDNAARRLFAQLVSGVGYLHKKGIVHRDLKLENLLLDRNRNIIITDFGFANTFDAEEELSEEEELNLSDRDFVKKLGLDRVKTNGTRKGDLMQTSCGSPCYAAPELVVSDSLYTGRKVDVWSCGVILYAMLAGYLPFDDDPANPEGDNINLLYKYIVNTPLTFPEYVTPHARDLLRRILVPNPRKRADLFEVARHSWLSEYAHVVEFITSSTTTPNQIQNTTVPSEDDDFAEASGIGRSASVRESSKTKANTPTSVGGLASKHAKIDADAEAAAIAKAHKDNKRRTVQVEYVAPTTQTQRGEAAAAGSKSRARSSSQGPVEIAENQNSQEKPLPRDPPVSRDSYRASRQGTRPPSAHRNTAAAPSRPTRDARTTSDNAFTPSGSGAQASGRPQTGGSMASGSMGLGAGARGSYGQPIPPAVAGTNAHGRIQQPTTQDSQAMGRPSVSIPPKFAKVAGFAPEQQVAQSQTPPQSSDGRGHGHKRSNTIGSLLGRNGSIFGGKNRKRPESQIADKSRKYPPVSMPNNMPAEGQPRPSIDSRASRRSFSLGLGKKRSGSIAGSQTSHEKQNRRFSLIPQSFSLKAIGIGRDYDRPPSEPQSQPDLPIQDPPEVDEHGRYVDSRGQSRGYDGGYDQGYRQPPGSSSAPQLSRQEWQDQQQQQGYQQQQQQQQQHVGPIGQPSAVPAYMQQGTGLNTGSESSFENAQNRRHTGAPYNASGHSESEGYDGQQFGSSRGNGRSGVLQKNKRFESAEYGGHQGSSGAAKRVMDFFRRRGKARGGDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQV5</accession>
    <name>A0AAD8XQV5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_645737</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371814.1">
        <property type="nucleotide sequence ID" value="XM_060509879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQV5"/>
    <dbReference type="GeneID" id="85393778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000098">
        <property type="entry name" value="WD repeat-containing protein slp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="280"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="408"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="64528" checksum="FF6B453A2C74950C" modified="2024-05-29" version="1">MATASVSTPIKSHKGLFSSRTAGGRMPLTPSPRQHSTSVSVNLNSSPFTPEKQSGSDAYRASGKSTYGGNLTAHLARSTTNKSSHRDSPKSNIARGVSTPRRALELGLSDFTLTSSGTSKTPSSAKSKKTSHRQKTSKTTVNYGGDRFIPNRSASSAISNAGSSKLDRPDKRSKASVSEASNVLSSATEDAIAALEGLNIEDEEPSTYSRPSPNTVAYQDSLASACGVSLNTRILQFKPAPPESSKPIDLRQQYNRPLKPASATSAQFRRRVATAPERVLDAPGLIDDYYLNLLDWSSGNQVAIGLERNVYVWSADEGSVSCLLETSPDTYVSSVKWSGDGAYVGVGLGTGEVQIWDVAEAQKVRSMFGHDTRVGVMGWNKHLLSTGARSGLVFNHDVRIAEHKVAELVSHTSEVCGLEWRSDGAQLATGGNDNLVSIWDARSLSVPKFTKTNHKAAVKALAWCPWNMNLLATGGGSYDRHIHFWNSTSGARVNSIDTGSQVTSLRWSPHYREIVSSSGFPDNSLSIWSYPTLVRNVEIPAHESRVLHSCLSPDGQMLATAAADESLKFWKVFEKKAGASAGVGSSTSSAKADMVKQMTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYX8</accession>
    <name>A0AAD9CYX8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_569437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368944.1">
        <property type="nucleotide sequence ID" value="XM_060504196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYX8"/>
    <dbReference type="GeneID" id="85388095"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="814"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="839" mass="93919" checksum="0E97228680211EA9" modified="2024-05-29" version="1">MPHSQARRYSQFILHDIQNELNEGDTLIFVDFPAPANPADSVDCFIYAWNSVRFRMPSEKLLATGSSKFAEMLNPTYQFRVQRRRKIAKNLPPGIKYVLDLTPPSEGDDLVFQMTEASLTPGIMNWWTAFDKHDVDDYVVRGHDDICSCWKETKVDSFNTIIDKISASEASRDENKERDPEMEYAISSAIRESLRDVIPENGKNKERLYSEDKGLAAKVLEKKSRGDFSAPAVPPYRRIPDYCPIRHRVNILRLMCIIANKRVFIDSAARVWTLVAVANILDCTPVVRDLVLQWITSPNNTSFIEVLPEESLQLGVTLKLDAVTRSAFRILVNELALEEAADVKGTPKAATYTVFGRKRHDPGDDLNNLIQHAARAMVERVSWPVNQLVSETIFDDLQIPEWLRLQNLISMLSSCPDDPAMVKAKVSAMTVSFTLKTLWENHVVYKVLRKPLDADDLQKIDDHRASYVDIQNFNRFEIIYNQFNNVQKALCTFMYETVGNKWTSLSEIFTSSASGQMNVYKLVTTLWEHLKEVLVAHPEFAWDGAWMAVLNLPRPLSMKNPFDTRELDMMGAYRYAFDTREFQKPLQDFLKPFYQECVRADFEIRMNLTPHLLLKLHHNELKFLPLWAGGNDDGTGGVFEHSLPPADYGPAGPGPAYHTGITIPSDASSTSGSVSSVLRQLRLEGSGSTVGPGSVDVQDGISTVFNPNRVIADDVSIRTESFTDGDSEYGNAKFTVPADGQSVAEAMSTMVLDESQDQSDTGTSINFDTDADEDDEVMTEVGPEDSRSREPTPEYVVEGSGARTAFSSCENQPASAASSSKNTAPSSSLLDDDDDLVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZD8</accession>
    <name>A0AAD9CZD8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369347.1">
        <property type="nucleotide sequence ID" value="XM_060513608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZD8"/>
    <dbReference type="GeneID" id="85397506"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42053:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="23328" checksum="6D78ABBC569A28A2" modified="2024-05-29" version="1">MPVNRPKLAQLATPVTSTFPSENMFSASTPLSARPMSCKDLPVKTPISPPTAYTDFLKAMSLNSPAAFKPSTSGETTPESTPDSLPSTATSEQTDISCKCEHEHQAPATAPAIPPSPFTHLPMSAPPTGANSFPSLKIPPSPAVSHLDSPMSARSPFSARSVHSVFDWDAALKAKRLNDSKKPSRTSVRHIREVVTRTVTYTPRMNPAPKGKRRKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZW0</accession>
    <name>A0AAD9CZW0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_36243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369618.1">
        <property type="nucleotide sequence ID" value="XM_060502587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZW0"/>
    <dbReference type="GeneID" id="85386486"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="413" mass="45784" checksum="64CC4D1C6F5DF11C" modified="2024-05-29" version="1">MPADFAFVTVSNSGRTQPTDRSGFRSRCMIGKNRQEGSRRSKQAARKAQRAAAQTASENAGLQSLHHSGSPIKPWPCTAYNEKQQAGEGSQALSTEEVARDDTSALMPPVPHPPPSDMSLIRFAEELERPSQEILFRLVNFSALKGTFYPIEHCVDLPRSTNSEALSFSWILQDKIFLHSALFHSSAVHEHVQRRQPGRMTQFHLRRTIKLLNEALSQPDSHRNEAIFHVILTLALMAGLWGDFSTTAVHLSGLRQIVRLRGGLKYLRSHPKLHFKLDRLALSWSLGTGGAPYFFTGPISWKSCFDAQSGNPTCEAGPFSCNVVSDWRLAAVWQDLRHLVDLINDHLACNSLLDGSLFQDSLGSIQTRLVHLQNGIDDRSDECLRLGMLAFLSTTLQIPGVKQSKAATSCSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0L1</accession>
    <name>A0AAD9D0L1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370098.1">
        <property type="nucleotide sequence ID" value="XM_060513483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0L1"/>
    <dbReference type="GeneID" id="85397381"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="19419" checksum="7C02C1B13A2B6339" modified="2024-05-29" version="1">MSCSHDNLRADIRQYGPGKKLTLFPHSPPDPHGRSTYKHNDPANNLGVEIIERLSNGSDGDNQVLLVRVFHKPVTDLKFTVPDTQEIVVVKIFDPLFNPEDAEEGPWKVASRADMKLSREAGAYKELHKNNLTGYPRLAPQYCGCWTTRLMSYSPDFEGVTRHVGLVLLEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1V9</accession>
    <name>A0AAD9D1V9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_788323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370086.1">
        <property type="nucleotide sequence ID" value="XM_060515677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1V9"/>
    <dbReference type="GeneID" id="85399575"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="39466" checksum="D156DFDA898E5B45" modified="2024-05-29" version="1">MSTRIFQRPSAVDYILGPTPIPTYPIKPTDRRVSEPSKGVRAVRVPHLVRRDVSDYLSQAFNLVRHLDNSEWGSLLGHAVLSQNPVRYIVTEHDSVSAAEVHILDTADRILHFALEHGLLPGPPRNQTNNTPMIQSWGEATLSVEFNGNPDERHQLRADRIYCRTLKTPTDPTPIPNLNRIGDRVARSRCFMVWEVKAHHALDKNSLYTSAKDVKNTLVNFVHYKKKRGQDKDIDDGRLPQTPPPNPDDQSNRPHGWNTEDWYLILQAAAYACLYRTKYVAIFCWGTLYLLHFKNLSLSPGVTVEEVWKKGPGANCDITVVTDTSLMVAAVVGFAIEAYNNTPRDDIDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3G9</accession>
    <name>A0AAD9D3G9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371750.1">
        <property type="nucleotide sequence ID" value="XM_060515998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3G9"/>
    <dbReference type="GeneID" id="85399896"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="SPRY" evidence="6">
        <location>
            <begin position="276"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1731695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="421" mass="45533" checksum="A56F43268824D9C9" modified="2024-05-29" version="1">MCFGSKADKDDTPAPRPAQRPPSLQQQDTKMTSSNQQQQPQYAPPAGPPPGQHSAQQQYAPPPGPPPSQSYAAPNGPPPGRADEFAPPSGPPPSHGGYAPPSGPPPSHQQSGYAPPPGPPPARNDYTAPPQGPPPSHKDYTAPPPGPPPSDSKKHDWETAVPDTTLFPPPPAFFSGFDRSPANNSTEQESEAGEAWVAQYPLVKPIDLDASALEALRTHRIWLLQPQGFRGTMAQPVSGKWEVTTQRNAPDSTIIGYPPLYSVKHNSPLATGKPFKVYYEVKIRGSASEVDLALGFTALPYPNFRLPGWHRGSLGVHGDDGHKYINDRWGGKSFTTPFQPGETLGIGMSFTAQGGRMSVEIFFTRDGRLAGSWNLHEEGDSEQDLPVNGLEGYHDLSCAIGTFSKNEYDIIFDPKLWKYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U441</accession>
    <name>A0AAD8U441_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000355">
        <property type="protein sequence ID" value="KAK1701602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357017.1">
        <property type="nucleotide sequence ID" value="XM_060509866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U441"/>
    <dbReference type="GeneID" id="85393765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="123"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="449" mass="51645" checksum="DB843298EB451CB3" modified="2024-05-29" version="1">MATQRLTESAGFTYYPLNEDRNEIRVLNLQTIERPPLAKFRDEPPEWHGLVHCTIEHVSLDAHLPDYRAWSSQTPQLSRRNSDERWRRFSNEQYRSLSPTRVSSPFERPRAHHRYHRFSWGDYGALSYTWGDQTVRVPIIMNGQVVLVGQSLEAALRALSSDPEYIDGLKVWADAICINQRDLAERNRQVKRMRQIYGRALIVSIWLGDIPNDSISDMAQLHELIVKSKDKAAASEVLEVAMTDPEKKETIRRAIDVVVKKTYWSRIWVIQEKCLGPFNPSILFGTFRMGLVPFHNFLQGVTNIHGAVRAREKVWRILKLMELVTATQERVRRGRAQTNEERRQDQDDLGLLLMIGRMAGSLDLRDRLYGLMGMIPEYVAKLIEPDYTKKVEDVFSDFASALITGFESFDIVLTGTAESTLKLPSWVPDLTSPWDPYLCCCCCCCCCCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U668</accession>
    <name>A0AAD8U668_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_642459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000201">
        <property type="protein sequence ID" value="KAK1707985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358201.1">
        <property type="nucleotide sequence ID" value="XM_060509617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U668"/>
    <dbReference type="GeneID" id="85393516"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02569">
        <property type="entry name" value="PseudoU_synth_ScPus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041707">
        <property type="entry name" value="Pus3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF5">
        <property type="entry name" value="TRNA PSEUDOURIDINE(38_39) SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="5">
        <location>
            <begin position="369"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1707985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="628" mass="70299" checksum="80C4A50A415EE95A" modified="2024-05-29" version="1">MKPLHELFWGLCLHCPPSPSLNLSRHAGGLLHGCSQVLARRGGQYQRHHHLRRFTTTHQHLTHPYRPSSIFAARRFSTAPVANMADVSGRYESWDQARLISRIRQLEHELDKRDAASKASGAGSGTPSNKNGAGAGAAGVATDGAPPVKKRKKEAKRIDSSRYSTRFIALKLAYLGKRYGGFEYATSASLPTIEGELWNALTKSCLIFPEDQDVVNFDCCEYSKCGRTDRGVSAFGQVIGLRVRSNRPVPKKQEDPAPAAGAEGDDTPMEGTEKVEEEQKEKKPEKAWDEINDEIQYVKVLNRLLPDDIRIIAWCPSPPPDFSARFSCEERQYRYFFTQPAFTPTATTVDGTPDGMKEGYLDIDAMNQAAQSFIGSHDFRNFCKVDGSKQITNFERRMFEAGVEEVKDVGTVLPYLGASAVDGSQLPKVYSFNIRGTAFLWHQIRHMVTILFLIGQRLETPDLVTRLLDVENTPRKPNYDLAHETPLVLWNCVFPGDDESRTSNDAENALHWVYGEADVVENLWSHYREKKMDELLANRLLDLVSRQVQGTESKAKGKRVFQGGHEGKLSGGYVPIAKKQLTPSPAEINDRWAQRKGFKNSDEMRESKNWRKVIKDAKQAAAAGDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6K6</accession>
    <name>A0AAD8U6K6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_534792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000343">
        <property type="protein sequence ID" value="KAK1701703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357044.1">
        <property type="nucleotide sequence ID" value="XM_060503342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6K6"/>
    <dbReference type="GeneID" id="85387241"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1701703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="461" mass="52719" checksum="9CC461E6A025BD63" modified="2024-05-29" version="1" fragment="single">MKLSYRLSSLVRKSIASAPDTFGIAIMTVWPEADGRPRTISSLQLKSEWVICEIQGHDGWEECMQTVQYNTCTGLLLVDNRPLGKLPKPPEHTEVLTELFGEQALLTHPSDMPGMDYTLTVKHRGYRIDIGYDSSSIVIRATKGQQYLQFIHRSKFKSRDAWDLPGPLLNDCVHWLDPRSGKVLIIPNADKWKIGHHYWILDIQNRSCTNQSSRLVDTYSPLFKRVARIFSGFEERMHLLVFQPHTGHLSVEIRRLQLLFYVNARRLLESPQLGSEIDLDQDAGTWYGLESKLVLRNPRDIQQRSILTPIGPVEAKQIDNNMLVRMLPSGRYGKFVINRHLGRIESAPEPMLLYMKAQLHAYTSSAFPDPLTERTGTEEALQWLNSGICQPWSPLHSGPVTVLLKIAQLTPQHEYYPTDLKVMKMDRWDVSLTEGVQHEMFRPVVKQILSISAELQSFALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8T9</accession>
    <name>A0AAD8U8T9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mesaconyl-C4 CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1713006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359622.1">
        <property type="nucleotide sequence ID" value="XM_060506245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8T9"/>
    <dbReference type="GeneID" id="85390144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000103">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF2">
        <property type="entry name" value="N-TERMINAL OF MAOC-LIKE DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37586" checksum="FF6B19DDB54657EB" modified="2024-05-29" version="1">MVSLVHQIRPAFRQCTARSKRSIATNATDAAAKLLDTFAGKDVVRKQLLDSNQLQRLSLTLNRKELHPGVDVSSEAPAQGTPLPPGYHLVYFTPTGVESELGMDGTDKTFNAPAPFTRRMWAGGKMQFVEGTSLKVGEVVEARTRLVGATPKKSKSGDEMVLVDVEKEFYGNDGLVVKDQRSWIFRPEVDVSLAAKTAPPRSERPPAFGPSTITDQPSAEGGIVRHFRWSPVGLFRFSALTFNGHMIHYNEPWTKDIERHPEVVVHGPLNLINMLDYWRDVHGKDGREARQVTYRAMSPLYAGDKYTLRTAAVENEERNDLLIEKGNIVCMKGEIIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U969</accession>
    <name>A0AAD8U969_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000248">
        <property type="protein sequence ID" value="KAK1705170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357554.1">
        <property type="nucleotide sequence ID" value="XM_060509748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U969"/>
    <dbReference type="GeneID" id="85393647"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF3">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="370" mass="40134" checksum="94457298B8FCF7E0" modified="2024-05-29" version="1">MTRRRASNTNQAINMGPKTVFITGANGYIGNAVARCFVAAGWTTYGLVRSLSAATTLAQEEIIPIIGAIDDLDAHANIQSHLPAKLDAIVSTTENTMDYIPHYQNTIKLLRTLGVASLSAGTKSIVIFTSGCKDYGIGPHFDGAPDLAPHTEESTIGTIPLLANRATYAQKIVDHGDVFTPVLVRPTNVYGRASSYYQAFFNVASRAAAKGKSLVLTAPPSTILHALHVDDCGDAYVAIASHPNVAETDGQAFNISAQSYETLDKVAQALVKEYQIKDGLKYIDEADAKEGEMWPPGIINFPQWTDSTKLTKLTGWKHRRPLFTESIHVYRLAYEATKAAGHENIKKVDGLLEAWTKNKAIIDLSSKKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9M0</accession>
    <name>A0AAD8U9M0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358892.1">
        <property type="nucleotide sequence ID" value="XM_060506415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9M0"/>
    <dbReference type="GeneID" id="85390314"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053146">
        <property type="entry name" value="QDO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36440:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="1">
        <location>
            <begin position="57"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="179" mass="19904" checksum="F563565214F7D712" modified="2024-05-29" version="1">MDVDDDVELGPGRDIPTDGIPVNFVPAKAGDVIKLGLITCRVLEDGSRTDNRIGAAEFTLPPGLKGPPAHWHEMHDETFLTTKGTIRYHIPKPDGTEDTIDAKEGDYVTVPVRAPHTFSNPTDQEAKFFNTYTPAYYINYFTLLGTYVQEGKPILPKEHLDAMSNYATLPVPKKYSQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9R5</accession>
    <name>A0AAD8U9R5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Alpha-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_770157</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3 7"/>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357855.1">
        <property type="nucleotide sequence ID" value="XM_060515338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9R5"/>
    <dbReference type="GeneID" id="85399236"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04081">
        <property type="entry name" value="CBM35_galactosidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="8">
        <location>
            <begin position="304"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1706600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="55625" checksum="A06E6DB45EFED4D7" modified="2024-05-29" version="1">MGWNSYNQVSCSPTNAGITAAINSLADRGFVTAGYKYFQIDCGWASRDGQRNATSGALKVDTNAFPQGLKPLSDLARSKGMKWTMYSDAGVRMCDPRVPSPVLGSLGHEAADADFFKTLNTEYLKYDNCYVDGPNESQNAPKDPRSDFVSRFTVMWKELQRVGIPGMLICQWGTPYSASSGLQGPAQWTKGISTSFRLSDDIATGWDNVYRIYNQAVHIVKSGIVGPGNIADADLLEVGNTGMTFDEQATHFASWAMLKSALMISTNIAALSDQAVAVLQNKDLIAINQDSAVKPIKLVQRWTGNRDLWAGDLANGDVAVLVVDLSNAARTLTVQLADLGITSATVKDLWTSKSVTNANSYSAQVNAHGSLALRLSNIKRSTAAGAKYNYVSVATGSLSSGANLQSCSGCTSSNKVGNLGGSSNGRVVLSNVSTSKAGTQTVLFDYINGDVGYLGGSNNERLASISVNGGAAQTVSFPLSGYNWSADVFKGYAVELTGFTAGGANTISISGVGSAWAPDFDRVGVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9X5</accession>
    <name>A0AAD8U9X5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_640652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358768.1">
        <property type="nucleotide sequence ID" value="XM_060509507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9X5"/>
    <dbReference type="GeneID" id="85393406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="139" mass="15748" checksum="7E52B810EBFA12AA" modified="2024-05-29" version="1">MAEMLGVKLDIPPEFWLAHCDQTCRFNPVDGIRNRQGRSKYWRVLVPQVREAPLMVEQEDAECVIEVGAFDRFNVVLPKNVALGSIKFYGLVSFWGMTHGEDGWTRELPDPQTCSSSVSNDTLVESSSLWIPGRRAFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAA8</accession>
    <name>A0AAD8UAA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360417.1">
        <property type="nucleotide sequence ID" value="XM_060514713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAA8"/>
    <dbReference type="GeneID" id="85398611"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042174153" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="177" mass="18841" checksum="781CF9F3129C1C7C" modified="2024-05-29" version="1">MYASNLITVFSALIAGASAATLPLRWSGVSNNAAIAGRRQTDGSATYHTTPGNISWSAQNYIWGCSPGGCSARFNVSAPTGYSSGAPGFNVVCSPIYIQQGWVPCLNPDNSPLSEDSQVFTIWTAGADRERMYLGVEHIYKRQEDGLTWNATAGTDILPVQNMSITFPVNTVVVLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAC7</accession>
    <name>A0AAD8UAC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_592932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000202">
        <property type="protein sequence ID" value="KAK1707968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358184.1">
        <property type="nucleotide sequence ID" value="XM_060506582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAC7"/>
    <dbReference type="GeneID" id="85390481"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05289">
        <property type="entry name" value="MDR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF4">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="8"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="33291" checksum="2FB46CA2E937E008" modified="2024-05-29" version="1">MKAVQIMGDEKSPKITLNTNIPKPSPEGANILVRVHAAGVTGDELSWPELYETASRIPGHELSGTIAELGPEYTGSLSVSQDVYAFTSADRGQCQAEYVACSPDEVTPKPTCISHLEAAALPIPVLTAWEAAIDHGEITADMIVLVTGASGAVGVLAVQLVAQLSGARVIALASSRNHENLKQLGAEVLDYNDPGWTSTVGGVDVVIDTVGGSVLSDVWKVVAEDGMIITVADPPPTWAFEDVVPEDSSRRPGVRYKYFIVSPNAERLCRASEMVEAGALKALAVKSFPFTEADQAWESARQRGRGHKVVIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAW2</accession>
    <name>A0AAD8UAW2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1713011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359627.1">
        <property type="nucleotide sequence ID" value="XM_060514815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAW2"/>
    <dbReference type="GeneID" id="85398713"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="38132" checksum="3270B5FCDEC65336" modified="2024-05-29" version="1">MVPIFFVGGTGHIGGAVLDQLLQKHADANVKVLVRDETKAARLVEAYPQIETVIGDAGNFDILEKCSQAADIVINTAPDITHDDGIKAILTGLKARGAAKGTEPYYIHTSGASLIWDEPAGSKDARRWDDIGDIGDICAFKGEAHTHAVTDKIVRDAATDVNVAIMSPGFVGGMSPSLEHPTPITTPALLLTARAFKSGWQIAEGENTHAWIHVWDLAKMFMILIGKAIDGTSDSEPFAIWGPEAYYFGTSENISFGEFMKHLAPVLKDQKVIESTEIKSVSVAEAARASIAGSDYDPDAPPPPPDTWAMHIAIMYGINMRIEASRMTKLGWKAEKGSILESFPRIVAGLLARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC77</accession>
    <name>A0AAD8UC77_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endosomal spry domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_640679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358774.1">
        <property type="nucleotide sequence ID" value="XM_060509510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC77"/>
    <dbReference type="GeneID" id="85393409"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="44470" checksum="45A188501843096E" modified="2024-05-29" version="1">MAPAVVNGLAHQARSFIAGRRLSSLPDTADITARSIDAGSVGPLAARSLLLARDSTGYKEDPHVGVTDPGNINNTAIFVLFGLIGAAFVITGIWFFFWARNGGFYFKENDWDDYKTTVLRRRGPNGTLLSGATKSTKLGGGSVYKDYDDNQTSISGTTLSGITAGPSDIGAREKRERKKEKRRREKEAARHKEKPSSQNYDEAGVLIDEEAEREAKKHLRSYRHEKPARVGGLNKESEASEWDGSTNPTESNVSTSLLSGQQTTPTSTPHKKSGGHGGIRKVYSTADRNEERERQRIRAEAKKLQERGRAAGSSRRDFSFQRASTVAEDQNTRGYALPPPREEPEPSMPGSWAESDITSALESDVGNKSYHHVIPGLSSQSAVSSDYADERRKRRKERRHRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCL2</accession>
    <name>A0AAD8UCL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361707.1">
        <property type="nucleotide sequence ID" value="XM_060514560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCL2"/>
    <dbReference type="GeneID" id="85398458"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF20">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="56"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="59628" checksum="BDDC1CCC2BE7A738" modified="2024-05-29" version="1">MFAGTFFHNGRVLVNAGTGLNAEATFVDSLLVIDEKIAAVGTRKEIEPLDLTGFRVHNLQQRTILPGFIDGHMHLLLLGQSLRKLDLSNCKTIDDIRFSIGSYAKANPNLPTILCRGWRHSMTPKGVSAALLDDIDPRPIFVDASSLHSSWCNNAALKELGVADMPDPAGGRIHRDEHGNPSGVLDEGAMMSIIWPYQASSSPKEERIKAIIAAVKEYNAAGYTGVVEMAMDEEAWDAIITLRDTQPDFPIRVAAYWLIKPTTDHNANSCQVRRAIELSRAYNSTTSSDFRIVGIKVICDGIIDACTAFLSEPYAPAGKPPPIWEPEYLDPVVKEANDGGLQVALHAIGDAAVRMAIDAIEKHTTPGRRHRIEHLELVSPEDAARLGRLGLTASIQPVHSDPAVLTEWPRLIGEDRCHRAFAYREFADSGALMAIGSDSPTSPWAPMENLYVAAMRRSARDPKFTGTFNEHFRLGLCESVTAATWGAASSVFDEKRTGSLAAGKCADFIVVDMKWDERSLLQAQVKETWFGGRKVWDIRDSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCP2</accession>
    <name>A0AAD8UCP2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_641982</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000192">
        <property type="protein sequence ID" value="KAK1708673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358355.1">
        <property type="nucleotide sequence ID" value="XM_060509585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCP2"/>
    <dbReference type="GeneID" id="85393484"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000512">
        <property type="entry name" value="Signal recognition particle subunit SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="11">
        <location>
            <begin position="542"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="536"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR038922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1708673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="642" mass="69997" checksum="44938F65539A80FF" modified="2024-05-29" version="1">MPSDPAANLSALLRAASIEDHEEVLKAANASLKASKTDIVAQRTRVVALLKLDRFDDALRAIADGGDKLEDASLLEKAYALYKTGKLQEAREVANSKPQRSFRHLVAQVAYRAEDFKDALDVYSSLLEDEQGEESDLKINQLASAAQLEWKVSNSLDGEDTPIPAAEDADTFELAYNIACGMIARGELSEATKLLQKALRLCDDSEELSEDDKKAEMTPIMVQQVYVYTRLGKTEEALAIQKRLSISEDSDAESRLIALNNTSALATEVDNPYLAQRKFDTAATLSKQAKLFKYQESQLKQNKYILGLQAQKFDGVYEKSSKALAKASPTVSVDTNGLSAINATAFALRRSKAVEVKEVLPLIEKRPTDVGLLLTIIQLYLTANNPGAALSVLERFLQNLEEHGPSEVRFSPGLVALTVSLYRQQGRHSNIRSELAKASSFWEKHDGRHVDSLLRGAGSELLKSSEPTDLAAAGAAFEKLCQKPTADPIAAAGLVASFATSDRAKVTPHLAGLPPIDDLLQGVNVDELVSNGVATTAPAASQAKKRRLDQPADASNKKKRRRKLPKDYVEGKKMDPERWLPLRDRSSYRPKGKKGKKKAQEATQGGFVKEEETLELAGGAGSVKVEKAPTTSSNKKKKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCQ5</accession>
    <name>A0AAD8UCQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_590661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000157">
        <property type="protein sequence ID" value="KAK1711613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359166.1">
        <property type="nucleotide sequence ID" value="XM_060506355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCQ5"/>
    <dbReference type="GeneID" id="85390254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF55">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="587" mass="63186" checksum="11B4232336F4FE5F" modified="2024-05-29" version="1">MAVLTQYDWIIAVITLAFCGSSIGNGANDVANSYATSVAARTLTMPQVGFLSMCTEFFGAVVLGSKVTGTIKNNIIELDRFRTTPSTLILAMGCAEFASAFWLLAATKVGYPVSTTQTIVGALVGVGIAAQAQVSWAWSDGSVSQIAASWGIAPCISAAFAAILFGSLKFTVLERENSFEKAMKAIPFYLAFTAAILALFITVEAPGAPSLEELGAGTVCGIILGVFFGILLLSYIFFVPYVHRRLVKEDTRIRLRHIFLGPLLYMENPPIYLPAKGNEVVIDYYASAHDDSNATNEGDIEKQAVKTEGGNDRGEKLVGNDSNSDAPSPVPMSLEDVERGKKGPENPAVVQRYKRMPEPEERFLAPTAHLPIHNPRRIWSFIKYFFLQGVTRDCVTHASSQLAAIHGKAKKYDNRVEHLWTYAQVASAMMMSIAHGSNDVANAVGPWVAAYQVYMTGEVSEEGETPIWILVVAGFLLGAGFWFMGHHIIKAMGNKLTQLSPTRGFAMELGAAITVLLASRLGLPVSTTQCLTGAVIGVALMNFDVGAVNWRQVAFIFSGWIVTLPCAGLIGGLLMAMSLNTPQFGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCX6</accession>
    <name>A0AAD8UCX6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_656691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359271.1">
        <property type="nucleotide sequence ID" value="XM_060510895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCX6"/>
    <dbReference type="GeneID" id="85394794"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="189" mass="21181" checksum="BE6D733AF7082D87" modified="2024-05-29" version="1">MVCVGELWPLFGKCVDHSKLEKLHIGRRRVSVMETERVEDVSRRAVGAMDVDDGIRVELSRDFSPAGFGMQVDPLPSQPGGPGNPRPNCTETSVKPLGLNPVQRPTAVIHSEAHNPDKRDCGLTHFPYQSVPTGRHQIERRNIPTVFQPCGRVASFGGMSSPQNKHYDGWSRFLRRCRLPTCKPYTHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD98</accession>
    <name>A0AAD8UD98_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361846.1">
        <property type="nucleotide sequence ID" value="XM_060505764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD98"/>
    <dbReference type="GeneID" id="85389663"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="209" mass="23096" checksum="0C4502D0DA28EAD7" modified="2024-05-29" version="1">MDPAQLANAVTERVTIPVLGGVENWKEQLKFMLQTLSKQPGYLRTRWGPWAEDQQKLELIIGWVSPDACEKWRRSKDFAEAMARFAPVLDGEPAAYLLRFKPYAPHAVINSPIVETLSFEDCRESENRMREVIERASRMPGCNGVASGYSLCPPTSSSGDSIGRTFVAAIGWTGLEASRAADKSAYTGGMKTEVHHVNFNFPVKGFGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDF3</accession>
    <name>A0AAD8UDF3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_586649</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360853.1">
        <property type="nucleotide sequence ID" value="XM_060505968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDF3"/>
    <dbReference type="GeneID" id="85389867"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004032">
        <property type="term" value="F:aldose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019568">
        <property type="term" value="P:arabinose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042843">
        <property type="term" value="P:D-xylose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042180">
        <property type="term" value="P:ketone metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000018">
        <property type="entry name" value="Glycerol dehydrogenase Gcy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="7">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1717366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="33260" checksum="A285D433DB75E60D" modified="2024-05-29" version="1">MSQTSRTFTLNTGAKIPAIGLGTWQSAPNQVKLAVEAALKNGYRHIDTAFAYQNEKEVGDGIIASGVPREEIWLTTKLDNPWHKRVPEAITKSLENLQTDYVDLYLMHWPSSTDPDDLKKHYPDWDYVDTWRELQKLVDTGKVKNIGVSNFGLTHLERLLSDPSTKIVPAVNQIELHPCNPSPKLLDYCKSKGIHATAYSCLGSTDSPLYTNQTLLEIAKSKDRTPQQVLLQWGLARDVSVIPKSVSEGRIKANYDLDGWSLTDDEIKKISAIPDRFKVCDGTFLPDGVKVFFGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDW8</accession>
    <name>A0AAD8UDW8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_586139</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000103">
        <property type="protein sequence ID" value="KAK1718138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361138.1">
        <property type="nucleotide sequence ID" value="XM_060505917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDW8"/>
    <dbReference type="GeneID" id="85389816"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="162"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1718138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="41751" checksum="BDB32A4F11028552" modified="2024-05-29" version="1">MLLPTAARRSATTATTAAFAPRLRFDVSESIPRSYYLGHHHAALREISSRLSDVGLVLECRDYRVPLTSWNPVLDRAIAGRERIVVYTHRDLGADSPASVEQALRRFHNGSGRSVTGGGGGTSTTRQRVVFWRKDDPATTKQLLSEIRSVARSVDSLTGMRALVVGMPNVGKSTLLNKLRVHGMHKKQSVAKVGAQPGVTRKLSSPVRILDSETSSAGVSNDSMGLGEGVFVLDTPGVFMPFVSEAESMVKLALAGSVKDDRIPMEILADYLLYRLNLVDPGAYARYSEPTNEVNEFLTGVARRTGKLKSGGEANADSAADWIVKQWRVGNLGKFVLDDITDEAFKDKELAREGQGPLSMNQARRKEKEARKERAMNKSKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF08</accession>
    <name>A0AAD8UF08_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-ornithine N(5)-oxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_679932</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360570.1">
        <property type="nucleotide sequence ID" value="XM_060511195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF08"/>
    <dbReference type="GeneID" id="85395094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF10">
        <property type="entry name" value="L-ORNITHINE N(5)-OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="65148" checksum="8E9A24C657A3DC01" modified="2024-05-29" version="1">MSKALETPTYSQFACVGTGFSAIGLGATLKRWYGIGDIKFFERHSDLGGTWFINQYPGCACDVPSALYSFSFESNPDWSRVLPPQQELWQYLHDVAKKYSLIEKMRFGVNVEQCVWSEERKRWRMNIRHYETNQVFAHECQFLFAATGQLMQPREIDVPGSTSFKGRIFHSSRWDQTVDIQDKKVVVIGNGCTASQIVPAIVGKTKHLTQAIRTKHWVLPPVDNENTEFMKNVLRHVPGTQTLQRFLVFAAAENTLRGFYMTNDGNKYRKRARASAEKYMKTTAPAKYHEKLIPDFELGCKRRIFDSGYLKSLHSENLTLLDNPIQEIVPEGIRTREGVTEADVIVLANGFVTNNAVGGLDVIGRNGEQIDQHWESFGGPEAYNCTIASGFPNFFVLLGPNSLTGHTSTIIAAENSINFALRIIKPVLDGKGTTVEVSKKAEQQYVNQMQADMQKTVWSTGCTSWYLKDTTDGKKWNGSTYPYSQAYFWYRCLFPDFGDLEIRGPTHAGRRRRTWPKKLAVAAVVGYALSLLFGLARNPLARNRYWQQFSVGMQLLRALLMMKLANLRRRIGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF35</accession>
    <name>A0AAD8UF35_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_630992</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361802.1">
        <property type="nucleotide sequence ID" value="XM_060508873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF35"/>
    <dbReference type="GeneID" id="85392772"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="356" mass="40887" checksum="07848EFF06F85BE4" modified="2024-05-29" version="1">MAMASDRVLVAVDESLLAEFPKDGKVVEVTSLGLSDWCDTTQYNVQLPDGSIRRFFEKKARGDGGLEQIRAHWHSESSVYKFIPEYIPRPVAFGEYASQPKTYFLLLEFEDMIDDDVPPPETYMAVPSALHLRSAGKSPTGKFGFSVNTRFGNLTQPNGWESSWEVWWTTHMRFLLERERVIRGAYAAEDETTLNFFLDTVLPRYLRPLETGGRCIKPTLCHTDLWPGNVKFKLDNETVIVYDANALWAHNEIELAPFRNPRYPLGKAYFREYWKHVPISEPEEDADSRIIIYLIRQQVCLASLYPNELKLRDAFLSNMCLLGDRVRDESEESKNVERAQVYFEPHIPAPVPVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFG6</accession>
    <name>A0AAD8UFG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_630493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361982.1">
        <property type="nucleotide sequence ID" value="XM_060508833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFG6"/>
    <dbReference type="GeneID" id="85392732"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF230">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="43"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="47440" checksum="EACF0C1802F783F5" modified="2024-05-29" version="1">MGASEERDRVAMSESQDAPGAIELGAMRSPTSSRHHDPESSPLAWLCVLGSFMFLYPSYGFMQSVGTVQSYLQLHQLSEYSTRDLGWISGIFTSLALFLGIQAGPLMDAYGTKWLAPISVALYVPVFFIMGECTQYWHFILCLGVLGGIGGALTSTVAVAVIGKLFNRRKGLAMGVALSGSSFGGVTISMMLRSILPRLGWQWSMRIMGFLVLGIMVLGVVCFLPYPRLSTPISGAPVGRVGALLNFSAFRSPPFGFMAGGLFMLEFVLFGITGLLPTFAIAAGFPSNIGFSLVAILNGTSCFGRIMTGVIGDRIGHLNILLIMIGITIVFTGVVFVPFGTKHIGALYAFAALWGYGSGSFLSSTPVCLGKTCEPKDYGRYLGTMNFVVSFSLLVTVPIGGQMLESMGGTALSGFYLAILFLGGVCYFAARSLLLGGWLTLRASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFS5</accession>
    <name>A0AAD8UFS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YAP-binding/ALF4/Glomulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_636829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359915.1">
        <property type="nucleotide sequence ID" value="XM_060509275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFS5"/>
    <dbReference type="GeneID" id="85393174"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040347">
        <property type="entry name" value="YBP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28020:SF1">
        <property type="entry name" value="YAP1-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="67834" checksum="FFF8F47F2F19E188" modified="2024-05-29" version="1">MIEATNPPLAMADKPSGLQALRESKPPATDTFTYLTIIGEVLSPEILPDLNEILQDTQLTQDIGWDLVEMLVPVQGSQQCLETIAQLGNPREVILKVLEVLEKTVEEATDEEDDPATTATFVHLVGMLSILHKRLNVARPSRFVHTTLQSVYRTYHPRNPEMTAAVIALVRSLSGDKRPPLPTRQSSNKLDTPFTKSDPTKHAPDPEAAHKQQLAPTDPDTTKRLLQSFITCIIEAYVNCTGMEWASRLLEFYNPERVVMRKSVLRAFKEDDDLLARDALVGQLVALAGDLGLNRVRALSVKDIFEGSIPNSPLAVETDDLSPDNIKLSTGGVWCLVAYWLFSAEVFDADYEQVQMTMFPDHVKLLENFFGEDPQSRIVGNPGTTEALVVMGLWLENYKRISPSDGDFMPYHHLLTLVSVFHPSLSVRNVSTTLAGLVLHDDPDDSDRLKILEDLLENCIFSALQASAVTWLREELIVAQKRKLTNRFSTTDAVETLQYVLFPNMAFLKEQSVPEIWEYWVQNFPFHLQVANFAYFLFAGTSFQHLVPASMPGAVEQRYVEPLLHAVTTLQTALEKKEVDDQGQGDEVKTQLDILTMRLKSLPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG02</accession>
    <name>A0AAD8UG02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_701859</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363597.1">
        <property type="nucleotide sequence ID" value="XM_060511447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG02"/>
    <dbReference type="GeneID" id="85395345"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="3">
        <location>
            <begin position="7"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="35891" checksum="58BFD18ED4054823" modified="2024-05-29" version="1">MADNIKGALDLTRQEAMAIAALATAGIYNAVEIYVLIFSTFRQRRGRYFWSMVVANTGIFVHAIVSLIRYLSRGGTVVPGAFALMAWCAMVTGQSVVLWSRLHLVVYNRTSIRLVLAMIVANGCAIHIPMAVLWVLCWATPAGEQAGWIERYGVYEKVSIVVFTLQETFITGIFARQGFFNLKPLFAFKTRAAKLISWYLLGLFVLVFVLDVGLIVLEYTNNFMFQTTSKPLVYSIKLKVEFTVLNKLLAFTKMNSCDCHHLDDTPGGYTKGLITQGTTGTTKGFTPAQREMMQGGGSMVSPEPDRPDHIFDGTRPVSVEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG65</accession>
    <name>A0AAD8UG65_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ICE2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_583475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362342.1">
        <property type="nucleotide sequence ID" value="XM_060505663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG65"/>
    <dbReference type="GeneID" id="85389562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048309">
        <property type="term" value="P:endoplasmic reticulum inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041919924" evidence="2">
        <location>
            <begin position="21"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="48044" checksum="87E6369565389DD4" modified="2024-05-29" version="1">MWWFLRIVASAIFLLSIVLSIPVAFDVGGRDSGLAYSLALSAFYFVYSTIAVVTPAKSRVRWAISVILRLSQWVVIPGLLIWALSRFAVDAGATNWVERTLQGITTSKSTSWGEWVFGEGGVIETITLGGWDKTLRYSSPVFQLLEGFCTLLVIQAAGQITKWLVNRGRSDTWIIILLVISGSVLASAVYFLWRVAHFPWIDNSDAILIGVTMTSAFFLGAYGIGSGRGNPIESSLLFAYVVLCVYQIFTDYLPSESTEADQHQSSQPDFPPLPPIIMASYSTLLHMLGSLPHAVHSSLSLLYAAFQTITPSVIISLAFRLLVFYCATRIIPAVRESGARALMEEPTLEESDAANWLLGIITYFSPSILIAMYTSLLLQHFSTNDGPDGWTLRGGDPGGNVWRWTNVAATMTLYAIELYLGNEDHDGGLTNHWKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGC7</accession>
    <name>A0AAD8UGC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_633298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361083.1">
        <property type="nucleotide sequence ID" value="XM_060509023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGC7"/>
    <dbReference type="GeneID" id="85392922"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="224" mass="25858" checksum="EB25DA1B951545BB" modified="2024-05-29" version="1">MWAWIRIEIFRSVMRNEKLDLEIEHVDFDRSLQPADDDIWAWRMCLHTVDVLNYCYGGNKPRETYDQLVSYAAKWMRSVPESFTPVLVQAPLRGSLFPEIFLLNDSVVMGLLFYHINRILLTIHNPDAQRLAKVSKQAARSINKEIFTDVKILAGMADSISPCNPAHISACMAIVLAGDRFTIREEQEVLYELLSNTADDFSWDVSLILAHLKKSWNWPEDMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGL1</accession>
    <name>A0AAD8UGL1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_753134</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363942.1">
        <property type="nucleotide sequence ID" value="XM_060514308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGL1"/>
    <dbReference type="GeneID" id="85398206"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="356"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="651" mass="73291" checksum="AD3D0242C588C338" modified="2024-05-29" version="1">MEAAGLASSILTFLDVSYKIAKGTYEIYESATGATAENIHVSNVITDLEKAVTNLGTVSMSQDAELSKLSEKCRALSTDLLKLLSGLERREQKVFESFKAAIASARKQKDIASIEKRLEQYRQQIILHVSLNIYREQSPIKIQLERIRDDSTRFENEHAAKLVALHFQLSEVLEIMRRPDLRPSMNNQVPGDRDYIQTHFHSDDELRRDEVTGASNTTTHDPSIIHQIDKFGPVDDKLRDLAKLLNDFKSCANALESENKTLGILYFDTIFQREDSISTTTSDTFAWIVEGFMPSHNSKSNETAGSYSSEESQPSAFISPPGLDDEELLDHDYIDWEKILLAETHHRRATSRSLHSFLKDEGEVFFICGKAGSGKSTLMKFLGRHPSVGETLAGCANGRKLVLVNMFFWSSGDSLQKSLEGFYRTILFHTLSQCPELLEMVFPNPFGIGLFTRSAAMPLSELEAAFSRLQLLKNTTSYLFCYFIDGLDEYEGDALDQKRLAEMLETWARADNVKIICSARPSTVNLDIFGASKTFFELHHLTKADIYAFSKTRFEEYLSKPIFAEGREACLGMVQTIVARADGVFLWASLVVRALLNAALEHEDKFSIRRRLKECPQSLNQLFHQMLDSVDPSPSPLMSPELHGEPNSSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHA9</accession>
    <name>A0AAD8UHA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_585157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361521.1">
        <property type="nucleotide sequence ID" value="XM_060505825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHA9"/>
    <dbReference type="GeneID" id="85389724"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041919039" evidence="1">
        <location>
            <begin position="20"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="226" mass="23198" checksum="68A52DCD7F213589" modified="2024-05-29" version="1">MHFSTVLTFLAAVATLASASPSLNTKRDDTVCAPGTGFFQSCANGFRGCCKSDACTIGYCPGSDACTLGYCPTTSASEKRQDPTVCAPGTGFFQSCSNGFRGCCKSDACTLGYCPDLAIASSSKRAADPTVCAPGTGFFQSCANGFRGCCKQDACTIGYCPDVKTFETVTKTAPQTTATPTPESKSNANADPTVCAPGTGFFQSCANGFRGCCKSDACTIGYCPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHH0</accession>
    <name>A0AAD8UHH0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_707498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360785.1">
        <property type="nucleotide sequence ID" value="XM_060511547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHH0"/>
    <dbReference type="GeneID" id="85395445"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="45"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1716855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="49182" checksum="F281B2B4E0341FF0" modified="2024-05-29" version="1">MASSESRYMAEPPDGQGRFDAGTITTGALALGGTLTSLSIIFVGLRAFTRLSLVRRGLGSDDYLIGISLALAIIFYGLSVKLCELGVGTHIWQVEQADFSPSFLLHSIIAIAVYSLSVTTAKLSLLVLYLRLSPERWFRLITMTLIGFASSYALAYLLLIVLSCRPIQASWDLSAREGSVCIDKNTVYLVLSATNIIMDVVCLVLPLKIIIPLQMAARQKLSLILLFATGGFVCICAIRRTILLPPLFKSIDYTFDIDRQLNWASIEVNAGIMCASVPALKPFFVRYLPMFVTSHITARGPKTKKTTPDYQNYQHSNPYSTTIEANKKRRNVQSEAYELHSRDDLSLSSSDMPKDGSREDVAKLWSGNALRKESKSYRETIIESNPRHSDDGRPTIVDEIQPVVGYDSKGGPQQRVASMSGIRVTTETRVEYEVPWPDHRSPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP1</accession>
    <name>A0AAD8UHP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_631117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361844.1">
        <property type="nucleotide sequence ID" value="XM_060508885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHP1"/>
    <dbReference type="GeneID" id="85392784"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="483" mass="53143" checksum="DDF646ED821EE949" modified="2024-05-29" version="1">MTRHPQHLDTTEIESLHTMAPRSMFGLLALASGAYAVPFVSQPQTTVTSEPTVTPSQVAVTNVTSHGPYTGPSPTTTGALSTSILASEVPVLPPPDDAYDYPADGKLHGDQPAPYTPSGGIGTNGSAPVYRVQSDFDYQSLALALYQEYIELDLFHWGLATFSDEEFEELGLNAEDRYLLQFMAEQEIGHATVITNMLGAQAPKQCSYNYPVTNLREYIDFNQKLTRWGESGVYGFLPHLNSGPAAQLLLQSITTEARQQMIFRQFEGLFPMPEWHIPGIPQSWAWTLLAPYISSCPADQTRLIWQNFPALHILNQPNPYRINGSNVWNETTGGWANTAATTNITDTESCVNATDPLQDCNAAITQNRTMPLSYPGRQVFFQWDAPGQAVGPNNSYITATNVVEPKFAAWVSQLNVTFSPLQNISLESRTAYTIQPNVSTWEHDPAINSTMFVALTDTDMYVTAHNLTMINPHVAALAVYQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHS8</accession>
    <name>A0AAD8UHS8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-ketoglutarate-dependent sulfonate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_702914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363137.1">
        <property type="nucleotide sequence ID" value="XM_060511471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHS8"/>
    <dbReference type="GeneID" id="85395369"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="797" mass="88075" checksum="EA9ED4261B0D2D20" modified="2024-05-29" version="1">MWKRKPKSQPAPPPPSEDGPGSTPASASEAIVQPGSAFLSGPDASAPPLSYGTDPSDPDPSVLAGIASGLNLALPPETHPPLSSFPTQDACLAHLRLLTAFNRLKTETGYCDGLWDIWDARASTTTTNYMKHTDTRNDLDILIRLREKRWAIYLGRAVDRYAAWWRTFTPNMLLESDMLTRARYEGFPESNPMVWREEMLLPLDVLLVWHAHMLNPRLYLEDCLRYGHNSFWAAGIPWSIINTAVIGPTFDYVVSDACKAHWEANTNLAWRNEDDPDAKDVPCPACSKFVPIPWTTCGLPPGYSVAKQLDVVGQGLADGRLAHACPSCGIKITHESLRAAKFRDDIQASIHSNHAIPGTILDLDTGLPKPLQYGSDDTSGECPDRLFPTRLARRGLFAHILEMFKPGSKMRPSMMAVRDAMEENFTGKFADSKNLREVMNFPGHEDVTTFRPSLDGKRQTRKMMSRYWENSSPFSIDLVGCVMRQATFTEKMCKQLKWLHFPTTRDIVRNLLGKYARFFEIIAITSPTEGKVAVPTLDVDLAWHTHQLSPQSYFVFTLSKTGTFVDHNDKVDEDRLSTAFEWTSKMYQERYGEIYSECKCWYCETVRVMALPTTKMFGIGKEEKLLEAWHAASKTNNVPMPPAAESAHVSSHPAVHTNETTAQRTTIRPLRSEFRNRLEETHSKARKKASKTFKADSVKRMGPRGEDKTSFWGKDIAVDGPWASALAAVTTSAMYPAGPGFVNMGPGAVGSCATGTCGGATGCGSELVGMCSAGRVGSAWFGGKAGCTGMGEGGFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHU7</accession>
    <name>A0AAD8UHU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_743291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361609.1">
        <property type="nucleotide sequence ID" value="XM_060513137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHU7"/>
    <dbReference type="GeneID" id="85397035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF3">
        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001221">
        <property type="entry name" value="Amidase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="6">
        <location>
            <begin position="86"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="5">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001221-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1719525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="59652" checksum="984C39C6285DA06D" modified="2024-05-29" version="1">MAEWEQIARKHSEEQKKKIPSDWLLDNDKLEQLRGAGTAQEGRLIDLRAAKKSGILDSNEMNITENYTARELAGHIRQGTLSAERVVTAYCKRAAVAQQLTSCLTEIFFEDGIERARWLDKQMRETGKVVGPLHGLPISLKDSLHVDGHFASVGYVAFLIQDRPQGNAALVKLLLDAGAVLYCKTNIPQTMMTCDSENNIFGRTLNPHNTKLTAGGSSGGEGALVAFRGSPLGIGSDLAGSVRIPAFCCGVYGFRPTVDRIPFAGQSLSPWPMNWMSAVMPALGPLANSADDLSLLMEVVTKLNPWRYDGSAINLSWRTLDEPRSKPLTIGILPEDPEYILHPPVRRTLAEAASALEKAGHKVVHLATDAKRSAALGARISYQYFSISAPAVADFGEPFVASVAKGMHPFSTGDFPVDPKLDIPGQYTGLNMARAAYAQAWSQTWQEHDLDIVLAPGASCTAVPHDTFGLPVYTVMWSLIDFPAAVIPFGTGSATRDSEPQKAIAEFAPDYIPEATDGAPCAVQIIAPRFRDEECLEAVGVIDQILNARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIE0</accession>
    <name>A0AAD8UIE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_580001</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363838.1">
        <property type="nucleotide sequence ID" value="XM_060505302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIE0"/>
    <dbReference type="GeneID" id="85389201"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000041">
        <property type="entry name" value="HMG box family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="94"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="94"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="681" mass="74341" checksum="4B251282FB75CA4A" modified="2024-05-29" version="1">MTDVVSTPRPRRSTSSSGGISAHSAMERRASQETDEGPNSVGSAGSRASRKRVASIDIEEANTSKARNLSLETRPMSSQSGKDTICLCTPGLKIPRPRNPFILYRQHHQATVSTEFPGLSNPDISKIIGQRWKSQDPREREIWKQLGEEEKIRHATIYPNYRYQPRRGRSRSQTGPSASTSPGRCPNCGGRFIATPRTPSTPAGTPTAAKPKMQPHHPSEARGGDSDHLRRALPGGKQPYQHQHNNLRDVEEEYEPMSPSPELKRRRINPPTGYYQAVPSPGPYTGHPLSRQPRSTVSMPPTPPVAGYGPLPGPSSLARPGYSNMAPPPPRPPHPANAGPSRGPGYDESLRLPPLQTQSSPPLNRDNDTNDRPSAHPMTGMGIANSRDRYAQSLEAMIMTIPFWSKLKVLQKISPTLAPPGPTSPEIEIRGAVVAVEGADPRQLEQVGTAVHRSLLGLSEIDLKTWSEGPSMPLSVLSAEDDARMNDTASAGGSSSRKSSHSQPNLHASELFSAYMESILKWHVKSREIINHVSTKPAFAAEPPPLTRRASEGEAVGSRHSSISVPSKTPVALLPAGFSLTLSDKYACTLPIYDCYAPIDHWQWVSTLWRGIIGPDLVIYVKSVTEEEITHAGAVEFRGPGVMVVRVSHNKSLDEKTERRISFELVEWIRGGSYQEGIGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIF4</accession>
    <name>A0AAD8UIF4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_621546</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364917.1">
        <property type="nucleotide sequence ID" value="XM_060508275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIF4"/>
    <dbReference type="GeneID" id="85392174"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="56"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="47131" checksum="AA6BACD6FD28E892" modified="2024-05-29" version="1">MAAANVLVRNLNAIQETQQQASVSTIDHALDGQSRFGEIVAILAVGSVLSTAAVSLRVYTRVKMLRTFGLDDSVMVVAQMFLIGSAVAIGLESKWGLGFHSWVPPPEDYVPYMKSFYTSIIVYNIATCLVKVSILLQYRRIFAIDIMQKLTLWGLAFMISWTAMLSFLLPMMCLPVAAFWDSTIEGRCIDFLAIWYTMAGVNLVADFAIFSMPIPVINSLQLPRKQKRMLLVVFCLGFFTCIISALRIRTLRVAADTKDPYWDNVDAATWSFLEVAIGILAACLPTLRPIFVTLLPRLFNASSLQFRSSGRPSKYGNPYAQASEGNNRASFMHGLGFHRPMSSTDGLNRQDGVELSGQETETSAEYTVSVSTGAPESLDKMSRVKSKRDSVMDGQHVRGHIRTTTVVTQEVTFEKPSSAKSNPDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIN1</accession>
    <name>A0AAD8UIN1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_629176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362445.1">
        <property type="nucleotide sequence ID" value="XM_060508753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIN1"/>
    <dbReference type="GeneID" id="85392652"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014010">
        <property type="entry name" value="REJ_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51111">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="REJ" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="314" mass="30333" checksum="4F9F6915C8C3D17B" modified="2024-05-29" version="1">MLVPRHTLSNGSVLLCSTEHSDHISTSSSSSSSSTMGMAVVTTSTSSSTSSTSTDSSTPTDSSTTSILTTSSSTSSSSTDAPTTASSSSSSTDTASSSTDSLISSSSSTSSSSGSTTVTPTTSSSSSSTSSLDTSSTSSLGSSLTSSLATSSSSTISLSSLSTSLLGISSTLNSTLSSTFGGISSSSTSLLSLSSTSVPTISTSILPSSSSSTLVSTSSSLTSPLITLAQSSSSSIVVVSPTLTTDTRGIYDPSIGLAFPGPSTTPSTTPSTTPSPTSSATPSTSASSTGIASIPVGVLFNLQVLAAAVPTNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIQ3</accession>
    <name>A0AAD8UIQ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_418964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362490.1">
        <property type="nucleotide sequence ID" value="XM_060502973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIQ3"/>
    <dbReference type="GeneID" id="85386872"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF1">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE EPSILON SUBUNIT HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="340"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="770" mass="87791" checksum="73D72F70EB0D966B" modified="2024-05-29" version="1">MISRLIFSPSRPSRSTHARLTSPQDDELAFECEIWRMHSVMNVRQIFAGLICGVSSEAETKTSFDSDENSVEKDDPTPILPLRRAWTTGSSPATQVTKKSSHPRRHTFSHNSIKASQQRRSSPLIPLTLWRRKSNNKTTMSSLSDLQELLKEAAVDVRNDSDDMTYTWVPISRIHEILADHDAVVKAFQDENFEIGREMKSFMFDKAKTLVAVLIRRGRHKWLSFFHGGSFDNKCFPINFESVKIDKSCQKWTVASYKSNQSIKSVSFKVTANEVDGISKKDDDELANFCKQYQWEFFVPVFAPNEPAHVFDPRCPMPFVKEFEPYATNFSIVRHFVIHRSHLNFPRDDQIGTIVDAEDNPHVAVKELLSAQGLTADKFQDLAENEATILARLRNQNHPHFIRAIASFTQGNRHFFVFPWARGGNLRNFWKLQPSLSAASDDISIQDWNNYLYWFFEQLLGLASAVKNLHHPENDQHKYCRHGDLKPENILCFSKKEDDIGKGKIPTGVRLVVADAGHAKVHEEATEIRGSPTTTPKGTIMYSPPEADIKQARTRRYDIWSIGCLYLESLIWMMYGYDALKSFHLDVGPGEPYFVKGPPAELKVVVKEWIKTIKDDPRCAPVEKTAVGRLISLIEERMLVVRVTRRDIGNQQPTSLNVIVRRPTQPLDSDASARENPERADAKEVYEKMKSIFDAGEQNDLIWMIRDAKASARGPPTITRGLAPGDSRRPPRTRESLENITEISDVSLQKQWRERCPLGDATDALLIEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIV4</accession>
    <name>A0AAD8UIV4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pectin lyase fold/virulence factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_628922</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362594.1">
        <property type="nucleotide sequence ID" value="XM_060508736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIV4"/>
    <dbReference type="GeneID" id="85392635"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Pectate lyase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="203" mass="21789" checksum="75ADFDE2F5E6B46C" modified="2024-05-29" version="1">MKISKVLADNGDAIGIQASSKVWVDHCELSSDRDNGKDYYDGLLDITHASMAVTVSNTYLHDHYKGSLVGHSDSNSAEDTGKLYVTYANNYWKNIGSRVPSVRFGNVHIFNNYEENIETSGVNTRMGAQVLVESSVFSSVKKAITFLDSKTTGYATVSDVDLGGSTNDAPAGTFSKPDYSYSKLGSAKVKASVVASAGQTLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJG6</accession>
    <name>A0AAD8UJG6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_620851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365071.1">
        <property type="nucleotide sequence ID" value="XM_060508217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJG6"/>
    <dbReference type="GeneID" id="85392116"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF8">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_2G17475)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042257262" description="TRP C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="TRP C-terminal" evidence="4">
        <location>
            <begin position="280"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="718"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="797" mass="87568" checksum="B9485041EDB3422D" modified="2024-05-29" version="1">MLARLGLAGLVATCASGAYVQWQGCEGPSSKTDVLVPQSLRATLVPSDDGRQNQLTLQVGRWMEEAECQDLARRMPSATLEFEMLGRSAVYQTTTKTTCEKLNFSKNWRSSLINPFSLHLSISEDIGHLPPLSTFHTTLHLEGNNSEEISCRQANITPALSSIVTSIITYSTWAIFLFVLLVGILRSTYSTPITLDDEDDEEQRSIRTVLPNVGDCLQYLQFIFLTGGLSLRYPGFYQPVVSHLNLFSLFVNGPVTHGVVYDRVEDGIYVLNGTYGGTYGLELMTQIAGAPMTMDTWLNMVVLMFIIALSVALVIEVVWFMKRSRDSDSEFSRSAGGMRYTASRVLRGILSYFMFPLAALSFYQLDNASILPAYHTSMAVALILAMMAAFIWLIRKIPTRSLGVLVFHSTKRYRQLHAADDARRRDGTFIFVLFALTFVRGAAVGGLQISGPAQLAVLGACELVLLASIAGFQAYSTFSIGSIAATIRLCSLIFLVAFLPGLATPIGVKSAIGYLLLAVHGGMLLLGFFVPAFCELSKFVKGWWTAPRPEIYGLRQLRRREVSRTNLASMYTSSTPDTSYPEPNAVESPNAGYLRPTYRSDSPSTMHLASSTTSSRYFRPPRSSASISSVENQRSLGSSLYTSSTPSRTTSTSTTFIDKHSVQRSESIMSPSRLSESTEEESSSTSQRSPTRPSDGPLGPRWNDYSFREADLYYNVPRPPPIERASEELPRPPAPRPPFRSSSGLWARVTGQSGTGEQGFQVVRPRPASEQGFVVLRPNRPSNLGNGALGSTPRAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK22</accession>
    <name>A0AAD8UK22_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_627758</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363018.1">
        <property type="nucleotide sequence ID" value="XM_060508656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK22"/>
    <dbReference type="GeneID" id="85392555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="55" mass="5719" checksum="63EC9D0B5DA79037" modified="2024-05-29" version="1">MKDGWQSQSSQKPNPASEDGVIVIGADTQSGAQIIGPSLSEIHLTAQLLDGKGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKD5</accession>
    <name>A0AAD8UKD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short-chain dehydrogenase/ reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_626258</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363480.1">
        <property type="nucleotide sequence ID" value="XM_060508552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKD5"/>
    <dbReference type="GeneID" id="85392451"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF285">
        <property type="entry name" value="RETINOL DEHYDROGENASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="356"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="46585" checksum="35119DC921A91500" modified="2024-05-29" version="1">MPLDYFGYIAEAGLPTYVTENWWFILKTVAALAVLVFIKLWSAGASNTAERDMHGRVVMITGGTSGIGATTVLELGSRGAQIILLTHTPVSDPFLVEYIGDVRARTGNELIYAEHVDLSSLHSIRKFATKWIDNSPPRRLDMIILAAATITPASAKRKETVEGIEETWMVNYLANFHLLSILSPAIKAQPWDRDVRIIFASCSSYIGSPSLKEPLDKKTWSPGTAYKRSKLALMVFGQALQKHLDNYKRPDQLPMNARVFFVDPGFSRTPGMRRWLSRGSLLGLFAYIAAYPLPWLFLKSPEQGAQAILYAAMESSLVRAGAGKLIKECRIVDFARTEIEDDEVAKKLWEESDKLIETTEKDSAALRALEKKMEEERAKEAKEAEKVKEVESLVEAIKKGKESQKAKGRKKSKKETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKN7</accession>
    <name>A0AAD8UKN7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidoligase enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_576078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365761.1">
        <property type="nucleotide sequence ID" value="XM_060504888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKN7"/>
    <dbReference type="GeneID" id="85388787"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="690" mass="76763" checksum="D68C47ABA617C093" modified="2024-05-29" version="1">MTERQTQTTPPRVSFGVELEFFVAFVREGERDPDYAIKHELQPLVVVPPDDGINKLGLPHTAYDWDEDFVFHSIGDALAKAGLPVYGQGQCGVPGSVQSMQSRKAMDAFQLKTDMSLKADHVDGYRWQRVEMISPAMYNMNLSFDMTRLAVSVITTNFRCRVNPSCGFHVHVGVGPTQRIDARTLRHFAALLWAADPLISRLHPPWRATLAYSQSARVNEATPLGQGKGPAGATIDKNIAPQDLKKMKVLGRDRWLGDSIEVDTTFETMNHEMNLDQEDDEALLTSHEPWQHRRAIPDVRDPKSSEARSTSPFGFPPHKYDAPVSMPKYYRTSTANSAAPPRPRPPPINRRYTRVPGRMRKDIRGDPDFLDGYILGQGGSIECVEVNQPARWDVMSGVRDLLGADMTVAQVGQLMTPAFLPKHINYKFKAYDFYSVEHLAPQDGNTMRTTYPTKDHTIEFREAAGSLDVEWIATWARICCRLLEWSRDAEPTEFMCVMRLLAWAQEEEGAQYDVVDLLIDLGLITEARFCEDRLQQGEAAWWECANLGALEGSENAFGDGTGYPVPGFDDYEMPDVENGGGHRYPGVAFGGWDDAHGGEYRGGEGWDSSSGSDTFELEGKAPEAGEKSQTTKLDTSAKEAYGDVPTAGKTNTAAYSEEKRNNDVKEQGESVARASRSSSTSTTRPKITIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKQ8</accession>
    <name>A0AAD8UKQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_580748</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363554.1">
        <property type="nucleotide sequence ID" value="XM_060505379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKQ8"/>
    <dbReference type="GeneID" id="85389278"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="64"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="318"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="452" mass="50637" checksum="02987E23B354773A" modified="2024-05-29" version="1">MDGVSGITQCPIVPGGSFTYRWKASTYGSTWYHGHHALQYGGGLWGPLVIYGPSHVKYDLDLGPVTLSDYYHYPYEKIASDAISTSNDTAVYAPQSNNHMINGMNHFNCSLAPANTTCKSNAPRASLRFKSGKVHKLRLINTSVEAMQIFSIDGHKLIVTTMDFVPVEPYEVEYIILGVGMRAEVLVKGNGDPKRSYYMRSRIQCAATKVDEVLGTIYYDETPATVVPATKTVAALPSFSATCGDPDLHLKKPIYKKHVPKPDLTLLYDIDFRSNASGNHQWLMNNVTFKADWSRPLYIEAVDGHAEYLKDPQHILATIPDDVRHVRVVLNNHFSVHPMHIHGGDFQILSESDGFYNGSLKYPKNPARADTELLRRNGNLVVQFEAKNPGIWSFHCHTAWHASVGLYINFLVKPKTVRQSKIPDDVREVCASWDDYRQLHGENALPFDSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULL0</accession>
    <name>A0AAD8ULL0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">OMP decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Uridine 5'-monophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_753164</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363843.1">
        <property type="nucleotide sequence ID" value="XM_060514316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULL0"/>
    <dbReference type="GeneID" id="85398214"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="OROTIDINE 5'-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="12">
        <location>
            <begin position="36"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="10">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="369" mass="40337" checksum="8BD84B985CD3CC20" modified="2024-05-29" version="1">MTSHGTLKATFAGRAESASHPLTAYLLRLMDLKASNLCLSADVPTARELLYLADKVGPSIVVLKTHHDIVSGWDFNPQTGTGAKLAALARKHGFLIFEDRKFGDIGNTVQMQYVAGSARIIEWAHIINVNMVPGKAAVTALAEAAARWRERYPYEVKTSVTVGTPRSESFDDYDEDNNGDSYEHTIGTPRPSDVNGRKGSIVSITTLTQHFEPAPSPRFPRNESHSSDEVLYAGIEEAPMDRGLLILAQMSSAGNFMNKEYTDACVEAARENKNFVMGFVSQESLNTEPEDSFIHMTPGCQLPPEGDEENGAVAGDGKGQQYNTPQKLVELCGTDVVIVGRGILKAGDPQSEAERYRRKAWKAYLSRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM20</accession>
    <name>A0AAD8UM20_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_558080</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364500.1">
        <property type="nucleotide sequence ID" value="XM_060503534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM20"/>
    <dbReference type="GeneID" id="85387433"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="811"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="837"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="837"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="915" mass="101581" checksum="46E77F1875881E1A" modified="2024-05-29" version="1" fragment="single">KCDYCGSTFGRQEHLTRHKRSHTREKPFSCSACGKSFSRLDVLTRHAASHDEVANESRRPVASSRACQACAVSRSRCSKESPCRRCTGKGLECKYPAGRRRGPRAALRSPDESAPPRGRLDSQGEVMEYSDPVQVPQPPGMTEIPFSTPNHAPERRAVETSWTLPQVTGDNGQHFQVNNCEVGYGMNPMNNFIQNEEFPEQSAGISAINWLSPQYYSDFDWGIMSSVNEREAFPANLDGVQTVMNAYEAVRQGPWLNLLNSQPVQASNAALPPASAQQLNPSGTTPRSRPNGSTTGSVESSSTTATYYVDGAPSRAPFKGRPSQRSLVLDNLNTARPEDDTPTPSTAALGTPKDSDEATGLDLSVQAYDNLLQHINTEPFLQGRSATPLPSIAHARVYFRLYFQHFHPAYNFLQKSTDFYHEPANWPLLLAVCAIGSVYSRGEVNLCFRDLFLELLESAVRFYISTGALDDAAGSCQVSLASPGEDSVGLVIAQTSTLWLIHNLHNGVFGDRYDLAFLVRHFLINACRKMDLLGKREDTQQVAQYVDGPHALTRWLEREARLRTGLMIWILDAIVFLERGQDVLLKLGDAKGQMPCLDSIWDQPTAKKLGQLQSKPGEPAVTLPEAMEMLYMEKRLPPNLADFSTMVLTYAIIRRTKEAIYHNQIRLNSWTPTADVQKCGPGDTAEETWPPSLPILSRWRNSACDSLDLLHWNANAIIAKAGGWEHPVILHLHLSRLVLLAPITHLQTLAAAASARASSRNVDNSKVEKARSLVTQWALRDQYKARLSVVHAGAMLWHIRRYSVGNFLEPFGIFTATLVVWAYSTMMLFMKRHQNPSSHLASDGPGQQHSPMEAVAEVEEDPEPSFLHLDRPCDDEMVQTYVRLGHKMAGHMAKVGDICNDGAPRKILKEGMQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM29</accession>
    <name>A0AAD8UM29_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cystathionine beta-synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_579635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364098.1">
        <property type="nucleotide sequence ID" value="XM_060505265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM29"/>
    <dbReference type="GeneID" id="85389164"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42115:SF1">
        <property type="entry name" value="BETA-SYNTHASE (BETA-THIONASE), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="18936" checksum="1C00EFD89069BD11" modified="2024-05-29" version="1">MAALASTPAAAAPTSQTSETSSPFVSKWSSRYRGATVEDIDPPAALSLTPTDPISHALISAFERDYTHLTVVDAHRALVGYLAIPHLQALLDAGKVKPEDPLSKAMVRFQRKGRTYRVITMQTPLEELEAFFAGDGVEAKKSHFAVITDEKRRFVLGVATVQDLEEFVKRRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMG8</accession>
    <name>A0AAD8UMG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_619153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365582.1">
        <property type="nucleotide sequence ID" value="XM_060508104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMG8"/>
    <dbReference type="GeneID" id="85392003"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000130">
        <property type="entry name" value="Endoglucanase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF13">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="76"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="525" mass="61288" checksum="1A9AE549E6C5A359" modified="2024-05-29" version="1">MSNGILRTSGSSIVDAEGKAVLLRGTALGGWMLMENFMNGFPGREHQIRAALLKVLGKEKCDFFFDKFLEYFFTEKDAEFLVSIGFNCIRLSFNYHHFEDDMNPFVIKEEGFKHLDRAIEICAKYKIYTILDLHSAPGGQNQDWHSDNPTGYAAFWDHKHFQDRVINHWQVIAKRYKGNPWIAGYNPLNEPADVEWTRLLAFYDRIVPAIRDIDPEHILWLEGNTFSMDFSGFTKVFDNSVYAVHDYCGFGFPNRIGRYQGLADQDAYIRQMYDRKVAFMKEHNVPIWNGEFGPIYERKEYNPDYEEHNEERYKMLDKQMAIYTDEGIAWSIWAYKDVNVMGMTYLSPDSAWLKLLGPMIRKKRDLAVDSWAYDDAHLQPNLFGPLHKWFEDNVPAQYNKKYPWQWRMHMHVFRGIRGITMTEYMIPEWADYFKDKTFEELDELAASWKYENCVQRERLNELLSLYAPMTPGDKRLEGKVITSEVEKEQGKPKETVSGVGVFELAPDEKKKHLAQATATPVAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMR4</accession>
    <name>A0AAD8UMR4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="15">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_791010</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366736.1">
        <property type="nucleotide sequence ID" value="XM_060515727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMR4"/>
    <dbReference type="GeneID" id="85399625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02083">
        <property type="entry name" value="P-type_ATPase_SERCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000005">
        <property type="entry name" value="Calcium-transporting ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000021">
        <property type="entry name" value="calcium-transporting ATPase, endoplasmic reticulum-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000037">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000014">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005782">
        <property type="entry name" value="P-type_ATPase_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01116">
        <property type="entry name" value="ATPase-IIA1_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 15" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="822"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="885"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="917"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1726681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="996" mass="107734" checksum="47CCB7D7E0EC3AD8" modified="2024-05-29" version="1">MESAFASPTEKVLSTLGVNPKTGLTDDQVIASRTKHGKNVIPEEPPTPIWELILEQFKDQLVIILLGSAAVSFVLALFDNEEGWSAFVDPAVILTILILNAVVGVSQESSAEKAIAALQEYSANSANVIRNGQVSRVKAEELVPGDVVSVHIGDRIPADCRIIAIESNSFNVDQAILTGESESVGKDCDHVVKDEKAVLQDQTNMLFSGTTVVTGRAKAVVVLTGSQTAIGDIHESITAQISEPTPLKQKLNDFGDSLAKVITVICILVWLINIPHFSDPSHGSFTKGAIYYLKIAVSLGVAAIPEGLAVVITTCLALGTRKMAAKNAVVRSLPSVETLGSCSVICSDKTGTLTTNQMSVSKLVYISENGSDLVEHDVEGTTFAPKGSISLRGQTVTDLTRSSATVRQMTEVAAVCNDSKLAYDAAKGTFSNVGEPTEGALRVLVEKIGPCAPSNSNPEDCLHYASSQYESQLPRLSTYEFSRDRKSMSVLVQNGQEKKLLVKGAPESVLERCTHTLVGANGKRQPLNSKLADLIAKEVVDYGNRGLRVIALASVDNIGENPALKSAKSTAQYAQIEQNMTFLGLVGMLDPPRPEVAASIRHCKNAGIRVIVITGDNRNTAESICRQIGVFDEYEDLKGKSFTGREFENLSDSEANEAARNASLFSRVEPSHKSKLVDLLQQQGEVVAMTGDGVNDAPALKKADIGVAMGSGTDVSKLAADMVLADDNFATIEVAIEEGRSIYNNTQQFIRYLISSNIGEVVSIFLTAALGMPEALIPVQLLWVNLVTDGLPATALSFNPPDHDIMKRQPRKRDEPLIGGWLFFRYLVIGTYVGVATVAGYAWWFMYNPEGPQIGFYHLSRFHRCSADFPEIGCQMFSNSSAKSASTVSLSILVVIEMFNAMNALSSSESLLSLPLWANMKLVYAITLSMALHFALLYTPFLQNLFSILPLNWLEWKAVLYISAPVILIDEVLKAIERSYFSQKKAIKSTKAKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW0</accession>
    <name>A0AAD8UMW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_742160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363335.1">
        <property type="nucleotide sequence ID" value="XM_060513102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW0"/>
    <dbReference type="GeneID" id="85397000"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="433" mass="48563" checksum="E7B91A3B52050DE9" modified="2024-05-29" version="1">MSNSFFERANPPPRRKTCTACIKAKRRCDHGQPACLRCSRRNIACDYSAPPIPIRSKASGRDLVARTPKPRRQQRPSSIAPSPAPLLDDNAGSSTSLIPWSQNPNLLPLDMGDLGDVNFDLAFDELITTDAFLEGPLIAPSLTPKPDDMLVLSYDSAPGSLESVIANRLQYALDEIKKVPTTVVMENQAPWSHPYLYRAHMPRDMQDAQACCALYIAKNKTNSSFVLRTIQARAHELLASPIPKNRLDILARLHAILLYQIIRLFDGDISMRASAEHTLSSLEHTILALLPFVKWEPEQPATGPAQDYIACPTKDFWQEWIFQESARRTIFFTCFFLVAYSALVGTLTNGCEERYVFCQSWTMSAHFWKAPTVVDFAVAWKEKQHFVITKQGFEEALRNAAADDIDTFGRILLVGALGIEDARLWFYNRGGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP32</accession>
    <name>A0AAD8UP32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_793232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363890.1">
        <property type="nucleotide sequence ID" value="XM_060515774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP32"/>
    <dbReference type="GeneID" id="85399672"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="196" mass="21592" checksum="779ACAAA93D675D1" modified="2024-05-29" version="1">MSLRTLFRGSIHVVRFFQMATLSFTTYTICYAAWLRSQEYYNAIGYHGVSNQIFLDMKEAAMIITCAALGIEIFTNSDFNEPSDPCLSIMSLAAYSMGLCFYATMPAAQQYLAQNGVLTDLGNYADFSTLDTALWRTSLAYGVITWASSVVFVLSTVADQAERATLQKSGISGVGLHAMDQKIPSHDLKLDTRSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP71</accession>
    <name>A0AAD8UP71_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_576644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365459.1">
        <property type="nucleotide sequence ID" value="XM_060504936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP71"/>
    <dbReference type="GeneID" id="85388835"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF165">
        <property type="entry name" value="DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="523" mass="55179" checksum="A8D8EA9F3E9D21D9" modified="2024-05-29" version="1">MISPSFQAQLRAAIPDGPDAPTLPSPASLAAASASLPRRPPSHGTGGCTGASAKGEGNDDDGGTYLAPLGTEATLTHILTDIVPALNGQARSGRYYGFVTGGTLPAAEAADTIVSALDQNVQVHLPGQTVATEVESVALGMLADVLGLEDGSGSESEEVWKGKTFTTGATASNILGLACGREYVIAKRGGNVGQQGLLGACVSARVKGVRVLTSMGHSSLSKAASVVGIGRTNVVELPLSEDEPWRLDLEAVERVLREGEEDGVVSIIAVSAGEVNTGRFATGGRGEMERLRGLADRFGAWIHVDGAFGIFARALEAKPEFAKIRQMASGLELADSITVDGHKLLNVPYDCGMFFCRSLPTQTAVFTNPNAAYLSSAGASTIPSPLNIGLENSRRFRALPAYAVLRSEGRSGLAAILGRMVLLARKLAVWIRASEAYELLPEGEWDIEEATHMVVLFRARDEGLNEELVGRINGTREVYVSGTSWKEKKAVRVAVGSWRVDVERDFEVVTRVLGDIAKAWARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPI1</accession>
    <name>A0AAD8UPI1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoflavone reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_752921</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364145.1">
        <property type="nucleotide sequence ID" value="XM_060514274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPI1"/>
    <dbReference type="GeneID" id="85398172"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="35586" checksum="C5D5CC7D91764E02" modified="2024-05-29" version="1">MSLKTHKIAVFGAVGESGGIIVNGLLESTSPSFEVTALARPSSISKPAYEELRKRGVNSIVVDLDKPEIEIANALGGFEIVVASVHPAGVGSQVTLARAAKLAGVQRFIPSAFAMAVSPTANSSVQKSKEEVYAELRAIDLPFTIIDVGWWYHGFIPQLASGRTDYTVVLPELLRNLVPGDGNMPTHVVDCADIGKLIPRIIVDPRTINQKVMASSATMSFNEMFAIAGELSKEKVVKKEISAQGLRLMITDFEAQLQESPQNALAAIGKFCLEYYYSSFIDGDNSPEGVSRLGYLLAADLYPDFKPASFQDFLLEVLEGDVRIPYSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ21</accession>
    <name>A0AAD8UQ21_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase family 62 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_572511</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367453.1">
        <property type="nucleotide sequence ID" value="XM_060504517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ21"/>
    <dbReference type="GeneID" id="85388416"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000017">
        <property type="entry name" value="Mannan polymerase II complex ANP1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF2">
        <property type="entry name" value="MANNAN POLYMERASE II COMPLEX ANP1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="449"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="59202" checksum="E5643DEB290282E2" modified="2024-05-29" version="1">MLPSYSSSASKVVPRHHASGYSNGYPRGNTFEISPHRYQPRASTPANRRRQRLVTRLIIVAVVTIFFLVFVWPGASLTSIFSLGLLSASSDLQLETVRYYDLSNVQGTARGWEREERILLCVPLRDAESHLSMFASHLRNFTYPHHLIDLAFLVSDSKDRTLQVLNDMLEEIQANEDPKQPYGEISIIEKDFGQKVNQDVESRHGFAAQASRRKLMAQARNWLLSAALRPYHSWVYWRDVDVETAPFTILEDLMRHNKDVIVPNVWRPLPDWLGGEQPYDLNSWQESETALALADTLDEDAVIVEGYAEYATWRPHLAYLRDPYGDPDMEMEIDGVGGVSILAKAKVFRSGVHFPAFSFEKHAETEGFGKMAKRMEYSVVGLPHYTIWHLYEPSVDDIKHMEEMEQERLASQKEEEEKAEKAKKVKEQFGDASSQWEKDKTDMQNLVVGEKKKETKGTKEDTKEVTKEGKEAKSPKDADSKQADTNKKAAAADKKDAEGKSDKLAKKEKDGNGAAFAKKAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQA7</accession>
    <name>A0AAD8UQA7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_717397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368071.1">
        <property type="nucleotide sequence ID" value="XM_060511945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQA7"/>
    <dbReference type="GeneID" id="85395843"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000034">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000039">
        <property type="entry name" value="Trihydroxytoluene oxygenase (AFU_orthologue AFUA_8G02470)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="162"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="318" mass="36481" checksum="E363DFAEE5D53203" modified="2024-05-29" version="1">MTAPTRKINLVRIAHINYTYQNLERAEAFFRDFGFVEASREGTRIYYRGYGPEPFVLCAEAGAKDGFGGAAFVVESEEDLMYAFKTLPGASEPYELSKTPGGGRCVTFEGGVDKFPFHLVFGQVMREKATVFPERDFNFPTEKHREAGTFQRFDKGPAPVHKLGHFGACVTDFQKTYDFFTTRFNFIPSDLVHDETGRNVTVFLRLDRGDELVDHHSFFFFEGPKFHVHHASFETHDSDLQFLGHDWLRERGYENCWGVGRHVMGSQIFDYWFDPSKFIFEHYVDGDQMNSSHPPNHSKASPDSLHIWGPDLPEGFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQL1</accession>
    <name>A0AAD8UQL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anion-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_699838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364715.1">
        <property type="nucleotide sequence ID" value="XM_060511420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQL1"/>
    <dbReference type="GeneID" id="85395318"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000235">
        <property type="entry name" value="ATPase ASNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="10">
        <location>
            <begin position="25"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="339" mass="37582" checksum="A2C37C2660869E55" modified="2024-05-29" version="1">MAAIIDADDVMEPTLQSILDQKSLRWIFVGGKGGVGKTTTSCSLAIQLAKARKSVLLISTDPAHNLSDAFNQKFGKEARLIEGFTNLSAMEIDPNGSMQDLLAGQNEEVDAMSGGLGGMMQDLAFAIPGIDEAMSFAEVLKQVKSMSYETIIFDTAPTGHTLRFLSFPSVLEKALAKVSQLSSQYGPLLNGFLGQGGQLPNGQNLNEMMEKLETLRETISEVNTQFKDENLTTFVCVCIPEFLSLYETERMIQELANYGIDTHSIVVNQLLFPKKGSNCDQCTARRRMQKKYLNEIEELYDEFNVVKMPLLVEEVRGKEKLEKFSEMLTTPYSPPEMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URN2</accession>
    <name>A0AAD8URN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_617148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366141.1">
        <property type="nucleotide sequence ID" value="XM_060508009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URN2"/>
    <dbReference type="GeneID" id="85391908"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="462" mass="52894" checksum="FC3136A31424BC36" modified="2024-05-29" version="1">MVLVSEMESPNAISQVRFPVGFILSCDLCTIEYTQTKEKNLALVLSHRVLTSNCKRILGIALSNRKSTSAPLQISTRQLTRNRRQRPSTMDQSKNETSKLGGVYTYFQSLPDLISRRAKNFICGCLDDIILHTITSIFIKPFMSYVFFTTVVLVLIAEIAPHPWIFAFFSIFAYANQHIVDRVIAGLVNLVSAIWVDAVVLWFILSVHFFRERRRRIPRREWIATWEIISLGINAFVYFVAPAQDLSAAYDSASAAPSNEVEEFQMTWGHYASLLLVLREVNCAFVEYISQTKLDAQRVPKDGKYECFRRLWYGLRFWGWSVLSRATMYLCFMATWDAVVELVVWEYVPVAYGGLAFFGMIVGMLTIVVLWVLERWKAMWGVGVDLEGYGSDESDDDEGDDIEKDEDKEDEDDGDESDNDDDEDDSDEDDSDEDDSGEDDSEDDYKVYEFGRENHFPGNNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USI4</accession>
    <name>A0AAD8USI4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_197867</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367680.1">
        <property type="nucleotide sequence ID" value="XM_060501641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USI4"/>
    <dbReference type="GeneID" id="85385540"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000063">
        <property type="entry name" value="Alkaline phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1727625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="572" mass="62325" checksum="C54119AE280E2FFC" modified="2024-05-29" version="1">MSSERTPLINDRREGDDSDDSSRTPPGPSRLREIVLFAWALLATAALIVLAVWTQHRSSTKFPRPTEGKRNLIFMVSDGMGPASLSLTRSFRQHVEGLPEDDVLTLDRHFWGSSRTRSSNSLVTDSAAGATAFSCGKKSYNGAISVLPDYEPCGTVLEAAKRAGFMTGLVVTTDITDATPACFASHVLTRAMNDDIALQEVGDGPLGRVVDIMLGGGRCHFLPNGTDGSCRLDNTDVVKKAQDEFGWTYAGDRAGFDALEGGEKVSFPQLGLFAHYDIPFEIDRRNMSDVYPSLSEMAATALRALEKATENSDKGFFLMIEGSRIDHAGHINDPAAQVREVLEYDKAFKLVSDFVKYSKTESLLVATSDHETGGLATALQEPGHLPVYNWYPKALAKASASAELLSKKFLQKIASTSGKTINKEELKEWVNKELVVPGLGIDNAHPEELQALVDRPEVSVQTFAAMISLRAHVGWSTHGHTALDVNVYSTGGDEAQKIRGNIENTDVGKFLRGYLNVDVDAITEELKEKMNKKQLGAMDLQQQQMAALAEDPNTWSQSQSLEYAHLLKAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTL3</accession>
    <name>A0AAD8UTL3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_770317</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367574.1">
        <property type="nucleotide sequence ID" value="XM_060515341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTL3"/>
    <dbReference type="GeneID" id="85399239"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07730">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051013">
        <property type="entry name" value="MBL_superfamily_lactonases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978:SF4">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42978">
        <property type="entry name" value="QUORUM-QUENCHING LACTONASE YTNP-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="36361" checksum="ADE38A44E46A1576" modified="2024-05-29" version="1">MNDIRTLPSSDSTIELVLLDGGGLTTTDDTKIHADGYGRPYFLYNWCFYIHHRKSGRKILWDLGISDDRQMYTPFVLNYHWTSCNPVGPRRRLADQLQDLDVKTSEIDTVLFSHAHWDHCRPIKEEFPNAKVIFGRGTASHCSPGHIQNDEVQPMAQWDSRIFGDDKVRTENFQELEGLWQSWGPFQSALDYFGDGSLWIIEAPGHMAGNLAACAHLESGERIIMASDCCHSRDIFLGRREIANVKMDDGSRFCLHEDLDKALDTISRLRKAAEEYGMHIAMAHDADFIKDGNDPVLMSILHPMFDETVLNRIKTHGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW65</accession>
    <name>A0AAD8UW65_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hikeshi-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_572393</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367460.1">
        <property type="nucleotide sequence ID" value="XM_060504500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW65"/>
    <dbReference type="GeneID" id="85388399"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="21216" checksum="20609E8ACA7575FD" modified="2024-05-29" version="1">MSGPLFGIVPAGQPLLTDPTSAPSETSFLYSVSAARPFSHITVMLLPGIVLPPDTAAAIYFATAADVAAATATGQTPNFKFLGGIGTGKESATFKLNAGSNTNNGGDPSVMIGVSVEPAESVFSRIQEISANKASSSSNASSQPSTQLLAQNIIKNAFNFLASFSGTAGPGGVEVVPLKAFEEWWKKFESRVRSDPSFLERPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW70</accession>
    <name>A0AAD8UW70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_127248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368481.1">
        <property type="nucleotide sequence ID" value="XM_060501192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW70"/>
    <dbReference type="GeneID" id="85385091"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="181" mass="19700" checksum="78CD401AE201CD8D" modified="2024-05-29" version="1">MFNCTNTHLELSLGDIGQMPHGTRGHHGTSAYEYISTYGQLGGSEKEDGVELGEEKWRKRNIRFSPRQSTGGRWEGHAAACLASLCTPHTCGTGTGAERRNSKTRQNLGETAPAGQLTGSRGTLSHLIPCCFGRRCEAGPRLVIGLQFGHFCPFFCFSLWSGVNDGKSNHQRKGCCRGIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8J7</accession>
    <name>A0AAD8X8J7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_724326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358419.1">
        <property type="nucleotide sequence ID" value="XM_060512646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8J7"/>
    <dbReference type="GeneID" id="85396544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="213" mass="24334" checksum="0C1DB1A010A00BA2" modified="2024-05-29" version="1">MPIEIQPVLESDLRRCAEIEKLAFSGSPLEPVLFPGPMPEDIMGIRAEELAKQFREDTTVRFHKAVDTDLSGDEAIIAWSKWNAYSEGLPVPKPRVWGPGCNEEACAKLFYGLDEMRQRLMSGKKVVYLHILVTDPKHQRRGAGWQLMTPIVQEAVRLGVPAYLESSRAGHHLYQKVGFKDIDEHLIDFSQYGLEEPHINWAMLWELPNRRCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X938</accession>
    <name>A0AAD8X938_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_135711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358657.1">
        <property type="nucleotide sequence ID" value="XM_060501245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X938"/>
    <dbReference type="GeneID" id="85385144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1709746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="28833" checksum="AA08FF925E3C5446" modified="2024-05-29" version="1">MKARVIQEDQAITVARREPCSASFPQFDTPTKYTGDEYHGNQWRLYSPEFLRTYSDPFMECSFNNYFVMSRESDRQDCTRYCNASIHLTCREVTIDLCPEEWPRTAKGFNRPFFATVSEVAHYANEECHLITKPQSRVAVALVTSDLIKVSVQSSPINPPEHRDKWEPRENFDRQIPAVFEFYGVLKSRSDGEYDAVDCEAVTRLWGSRARRDREAFDGKDRKVNVETQVDSIEPSGAPRVVLWPDSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9L4</accession>
    <name>A0AAD8X9L4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_756858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1712988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359604.1">
        <property type="nucleotide sequence ID" value="XM_060514812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398710"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052391">
        <property type="entry name" value="E3_Ligase-Neurotoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133">
        <property type="entry name" value="ANKYRIN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24133:SF40">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="388"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="944"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1020"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1256"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1403"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1471"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="1541"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="289"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1712988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1982" mass="222524" checksum="AF18EDAB0EA9B88A" modified="2024-05-29" version="1">MIIPSLDVVYPIHMNHVPPGWRPLVNLICVHDLGGSPKSSWHHDESGKTWISDPDFLGSFKDSVRVWTYGYNSDPAANMTPASIALHADELLISMISNYSKYTGGSTVFIAHGLGGIIVKKAIELCSTYAEYFPIKGSTVGVVFLDTVHHATDSEGVLEAVKTTVAATLLKHSTRPSLDDVRQFAEAVREVNKTFLTQAPLDLTILNFIALRRIEITSEDGTSYKTLLVPKRRADMDPTQGQNLPVACHHFQLTQFPSPSDKIYSLLADQVGDMMTKLSSSSNKRVFCAPPPPLAPTTANPPPPSPPPGPPGPPGPPGPPGPPVSLPPPPRSGIPMGPPPRDQANEAFSLWAKKKEAADKKRHRDILVNKLGQWDEHHLGHDIHPTPDTCTWIQSHDFFKNWIKSNKTAGLFVQGATGCGKTHLAKSIANHLSWDRPRSPPDNNIVLSFFCNASTVRDKKPPIAQYFVRSLLQLRPVWSESIAPYYRWQELKSHFELPALFDILRDIMSQMQYSTGPPKTTAVFLIVDGLDDCDVTYAREFLCLVGSLLDHPVARSSPPSGLSLPGQGFPRETVRFKFLFTYSACEVLNLNSCIPNSARILMTDAAIRKDISTYVERELDILSTLRDLNGPPEGIRSWIKNKSESFFWFAKYSIEDAMSTVEDGEGYSFSARVFPCPSSLGKYYDRDLLPLFQTIDEDRKYALSALQIVLGYLGSPGRAEICDAIACLHGDPNLRFLDLPNFLRQRCPRLIHSLDEGDFKISHSSLIHHVRRSYLSEKEQHANMAFLCIKYLSRSDFGSFKSIMSPNIPESHPFYSYAADNWREHLRRAGDKVVRLLPLLGDFVNSANYRTWSAHHSWNIAMTYYRRVLMDDTFVSPVFAFIDANVGHLSHEIQCAGREEVWSLKKELLRQTWCYLYERKQTPGIARLIEYWRPDSCFAVHDIDGHTPLMHAAGSSKGQPKMVEYFLKRTKNVNERGSVSGGTALMILCTRLKTRDEDLTARLVTSLLDAGADPNISNKWGETPLLESCMRGNAAMVELLLRAGARPDMLSTHGLIIHPLRDAIMQYHNKVARLLIDYGVDLSLYFPWPNLQLPLTASITEENFDIFMLLLNRVEDINQLDGMGYAAIHLLTGPLYIDWLPHLLRRPDVDLELLSNGISGDRKKLIRRTPLSFAIVDDNFKAVELLLGAGASPCRHPASPDETPLLIAVETARTTKNKESVEESEVDISTGNTDIVELLLAYQSPINTLNRKSKKYAKSPLMMAVYYKDQNMVEILLRHGADPTLEEAYGLPGPLDAAMLDDEDIAMGMIKVLLENPLPPSINYVPDNPDFQHILIEASDMEPEVTRLLLAHGADTKRFLSYIPGCFTTPLHRAVEENKIETVKVLIEHEPALVTYQCEEGLVYETPLHIAARDGHIDILRCLLDAGAQPGQASCHWQETPLWLACESGRLEIAQLLYKMSPEALELRSYDGKTPLMVACEDGNLQLVQFLLGKGADITARCSMGASCVCSTVSEDNGAAYKIIDLLLQHGLGIDDVVGSTGFTVLGEACRAGDIPTVRFLLDKGADPAKGQKWPGDTSTTWRSALRVASLYECVKVIEVLLEHPQLASFIEDVDYYGDNVLHIDGSYHHQQASEMATLVYSACEKLRAETGVDHFQRMLSVKNSDMQTPLDMAIDMPHKGLSSEATAMIDIYLKRYIAELTASENRTFAQHKHLMRDIAIILLERRNYDEEAIRLFQALIVDVWVTREDGQCLETVFCMANCDLCDEDEQEQVSFCRLCGLRVGMKCVDEARLQHELVDVPVIKDRSIIDLNSEPVNEIMDLLKNDFIVTESPRVAEECLTTYFQVEPESEDTTLSLAVLHAFGYLEFRRRAWSPYLPLAPAVYKRIQPWEPMFIEPRRDFEEWVWGIETPPFRLRDELNYFLESGRRVAYKDEQATRLEQILSDVGWLYPQREVHDDDDSGVVIDEHSYSAEEILGGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA60</accession>
    <name>A0AAD8XA60_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="11">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_589141</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359827.1">
        <property type="nucleotide sequence ID" value="XM_060506204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA60"/>
    <dbReference type="GeneID" id="85390103"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="13">
        <location>
            <begin position="197"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1713774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="640" mass="68814" checksum="C14528008E1B1098" modified="2024-05-29" version="1">MEAALRQSKAMCPFLKSASPAKLRALSTSARPHAIQAAPQTTAVSPCGGTMSKLQLLAHRCPVMGKALTVQSAQYGHGRPAKMGNSSSVAGIRALSTNSKPGRANIHTSRSKDARAVDAPLLNKAQAPPGIPAARQSAASTVGMGNSDASKAKFNYEAYYNAELEKKHKDKSYRYFNNINRLAKEFPRAHMAGKEEKVTVWCANDYLGMGRNSHVLKSMHETLDEYGAGAGGTRNISGHNKHAVELEGTIAKLHAKEAALVFSSCYVANDATLATLGSKMPECVILSDSLNHASMIQGIRHSGTKKIVFKHNDVADLEAKLASLPLHVPKLIAFESVYSMCGSIGPIEEICDLAEKYGAITFLDEVHAVGMYGPHGAGVAEHLDFEAHQQGRPKGSIMDRIDIITGTLGKAYGCVGGYIAGSAKLVDMIRSLAPGFIFTTSLPPATMAGAKTAIEYQMDYDGDRRLQQLHTRAVKEALNDRDIPVIPNPSHIIPILVGNAELAKQASDMLLQDYQIYVQSINYPTVPVGQERLRVTPTPGHKKEYRDQLVQALDEIWTKLGIKRTSEWAAEGGFIGVGEADAAPEEPLWTDNQLGIEQAAKEIKAAGNISNGFVEALLERESKATTGQAVSSAIDTFHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB37</accession>
    <name>A0AAD8XB37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_587062</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360742.1">
        <property type="nucleotide sequence ID" value="XM_060506002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB37"/>
    <dbReference type="GeneID" id="85389901"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000006">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="17">
        <location>
            <begin position="32"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="148"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="18">
        <location>
            <begin position="289"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="512"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1716812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="699" mass="78635" checksum="7B7286C8D2495AF9" modified="2024-05-29" version="1">MPNTPDWVKALQPSGPQGTELLAQERAKSNLNVDQLASFMFTNEALERSERILNILKKEPVFDKTQNYFRGRNARIEAALARGKRLFQLTKEHNWSQQDYIVANDLIAEPTPYGLHASMFLVTLREQGTPEQHELFLKPAENYEILGCYAQTELGHGSNVRGLETTATWDPSDKSFVLHSPHLTASKWWIGSLGKTATHAVVMAQLILNGKKIGPHPFVVPIRDKKTHEPLPNVHVGDIGPKFGYNTMDNGFLLLNNVKIPHNHMLARFSSIDPNTSKYIRPANPSLIYGTLTWVRSNIVLPSGSVLAKGVTIATRYCAVRRQFQDRDAPAGEPGENQVLNYTMVQIRLLPLLAATFALHFTGRGMINLYNENQKRMKGDVGKLSDGTRNPGPEELNPGTDLLADLHATSCALKAYGSTVAGEGLEICRRACGGHGYSSFSGIGSWYADYLPTLTWEGDNYMLTQQVSRYLLKSARSVLKGKAGNNDTTRILSEFLRRRDIGAAFDVLGSDEDLVAAFAWRVSFLTFEALRHRDEDKQSWNSLLVDFWRLSTAHAQYMVVKNFHQALNDKATTEQLDKDTVGLLHKLFRLYALNTLEQEASEFYSSAAVTVRQITLARTKAVMTLLEEIRPHAVRLVDAWKFDDWVLDSSLGRYDGKVYEDMFKRASEDNPLNSVVFDPYPNSKVLFKKDERKDLRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBB2</accession>
    <name>A0AAD8XBB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_755275</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-nitrosoglutathione + NADH + H(+) = S-(hydroxysulfenamide)glutathione + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:78371"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:145544"/>
            <dbReference type="ChEBI" id="CHEBI:229723"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15734"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a secondary alcohol + NAD(+) = a ketone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17087"/>
            <dbReference type="ChEBI" id="CHEBI:35681"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361419.1">
        <property type="nucleotide sequence ID" value="XM_060514587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBB2"/>
    <dbReference type="GeneID" id="85398485"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000001">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="14">
        <location>
            <begin position="35"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="13">
        <location>
            <begin position="206"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1719335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="380" mass="40312" checksum="00E96213CC1EC3D8" modified="2024-05-29" version="1">MSSTAGKTITCKAAVAWEAGQPLSIEDIEVAPPKAHEVRIEIYHTGVCHTDAYTLSGKDPEGAFPIVLGHEGAGIVESVGEGVTNVKVGDHVVALYTPECQECKFCKSGKTNLCGKIRATQGKGVMPDGTSRFKCKGKDLLHFMGTSTFSQFTVVADISVVAVQQDAPMDRTCLLGCGITTGYGAARITANVQEGDNVAVFGAGCVGLSVVQGAVVNKAGKIIVVDVNPNKEEWSRKFGATDFVNPTQLGDQSVVDKLIELTDGGCDFTFDCTGNVSVMRAALEACHKGWGQSIIIGVAAAGQEIATRPFQLVTGRVWKGCAFGGVKGRSQLPGLVQDYIKGDLKVDEFITHRKTLGEMNNAFETMKQGDCIRAVVDMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBX7</accession>
    <name>A0AAD8XBX7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_583948</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362079.1">
        <property type="nucleotide sequence ID" value="XM_060505715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBX7"/>
    <dbReference type="GeneID" id="85389614"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF33">
        <property type="entry name" value="MEMBRANE PROTEIN WSC4, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="368" mass="37993" checksum="0740E6473B69B09F" modified="2024-05-29" version="1">MALSTKTTFIASTFPENPLKTADFSPPASSCSGIYLTNNVYAIDNDSKCLPNKFNGASTAFYSPGTVCPTGYTAQPQCSRNGGVRSVTTVTCCPYRGDMTLSCVEDDMTLANVWETQFCTWMAGPATVVDITRTDNGVVATQAVTMSDRDGVNAWGIRMVYQASDLVPKTTSGASIASATATGTAAAGSSATSGASATGTAAGADNTSGSATAAATSGASSGGLSTGGIVAVAVVVPVVAIAALVGLFLWWRRRKHRYAGVKPAETPTAPEMDGSSAMGSQSAYAYQNHGYAQQQHNGQYPQASPPASEMIGTDMAGYYNNDKVLMNPSGQHQGAGHTQYKGYTHPQPPVELASGEGPTELPADNDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD52</accession>
    <name>A0AAD8XD52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_580951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000066">
        <property type="protein sequence ID" value="KAK1723329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363384.1">
        <property type="nucleotide sequence ID" value="XM_060505400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD52"/>
    <dbReference type="GeneID" id="85389299"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="126"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="43268" checksum="DD4C362E95422B98" modified="2024-05-29" version="1">MRQHSRLQRVHGDHDPLPEFTSDTLRSVKASWDFFIAWLKITWFDIFVMSAIGGAALGIYNAPLAATRNFPIIFNGSGDIVYPQWAYPDRGWIIDTWLSALLSAAIPIAAILLAQFRVRNIWDVNNGIIGLIFSISLATLIQVILKQLIGGFRPYFLAVCMPDVTRATSNNSTGLNAVGFQQIMYSVDICTQPDRDKLKNAMTSFPSGHSTAAFAGYVYLFLYLNAKLKVWADYRPALWKIALTFGPLLGALLIACSLTIDQAHNWYDIVAGSIIGTAVAFGSYRGCYAAIWDWRFNHIPLQRRDQFVYSPGDGTEYRNDVFTRSGGWGAIREEAAEKSPPNRRSSAYYADQQAAYHGASDRDALPSQLPRTRYKLRRVSSRGDEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDE8</accession>
    <name>A0AAD8XDE8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_720958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363142.1">
        <property type="nucleotide sequence ID" value="XM_060512329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDE8"/>
    <dbReference type="GeneID" id="85396227"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000009">
        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="55216" checksum="4C3022550B78282C" modified="2024-05-29" version="1">MTGQPYNLWVGGQEKPGHAEQIPVEDPATGEIFANCHAASLEDVEETIRLAHETFKAGTWSRAPRHVRADVLDKTAELLTAELPSLIPLEVRQTGRAIREMRAQVPTLVKWFKYYAALLRTEERAVLPTVGKLHNWIDRVPLGVVVQITPFNHPLLIAVKKIAPALAAGNSVVVKPSELTPLTTLLLGKILQKAGVPDGVFHVLPGYGATTGKALVEHRLVRKVDVTGGTVAGRAIGSIVGGNLARYTAELGGKAPLIVFEQADVDVAVNGIAFGSFIASGQTCVASTRILVQEGIMQPVLEKLKAKAESISRRMGSPSNQESMMGPLVSAKQLSNVEALVNEALAAEGAAFTGGRRMSGTSSLDGTDFAKGYYFEPTVLVSRAEGDILKSRIWREEAFGPVVVVAPFKTESEAIALANDSEFGLGAGIWTRDVAQAFRVSEEIDAGIVWVNTHHRNDPSSPWGGATSASGVGSENGIDAYQAYTTTKSTIISYASPEEALAADDWFREGAGDVRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDZ2</accession>
    <name>A0AAD8XDZ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_721154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362861.1">
        <property type="nucleotide sequence ID" value="XM_060512355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDZ2"/>
    <dbReference type="GeneID" id="85396253"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="209" mass="22870" checksum="F1069D6B4E48FB59" modified="2024-05-29" version="1">MSVVISHFHNDHIAGTEVFSKGGATIVGHEITARTVKRNTQDLAADSPAIVAVPPTELYSGKKEMKVGNLSVELHNFQVHTPDGTILYIPSKQLIFAGDTVEDTATFIADAKSLPMHQKELQRMATFPISKILPAHGEPNRIATGGYNSTFINATLRYIAAMTEDVPEPAAWDQPLSQAGDLIYFAQYEEVHQSNADTIRRSRGRGNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE51</accession>
    <name>A0AAD8XE51_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361448.1">
        <property type="nucleotide sequence ID" value="XM_060514591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE51"/>
    <dbReference type="GeneID" id="85398489"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901444" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="20003" checksum="4B8DE0D0F1672BA6" modified="2024-05-29" version="1">MFPKTVLALLLTVTSALASPLETRQASTYFTPSSTFTYNTRTGAISPTYGTAVVSKSTSNAGNDLTALLTFTYPPAAAGKKCQFYFYLDAATSSVSGSRKLDVFTSLKPAPAGGSPGWGAGGPGNQRNVNIGRLSVAAGGYATWDATYGAYLTAPTDCKAPGTVEGFELVGVNDNDYVSWNTQVSGARIAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE79</accession>
    <name>A0AAD8XE79_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_579531</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364027.1">
        <property type="nucleotide sequence ID" value="XM_060505249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE79"/>
    <dbReference type="GeneID" id="85389148"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000003">
        <property type="entry name" value="C6 transcription factor (Leu3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="709"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="781"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="715"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="736"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="828"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="843"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="939" mass="100797" checksum="15C317D781BCF007" modified="2024-05-29" version="1">MSVTPQGAAGAYHDDEAAAVAAGASSEGQGQGHHHHHHHPDSPETPHSGHDGETPQNDAIHGGNPDDPKRPRACEACRGLKVRCEPDPNDTEGPCKRCKKAGRNCVVTMPTRKRQKKTDSRVAELEKKIDALTASLQARGSSAAPGAAPAVTTTTTSTHAALPTPGRDENPYNKGWGGHGLAREWTSSTVAGTGLSVEGLDPQEAHAAEKGRFDHITFPAPSAAAAGQKRKHSDRGDDTPSGSDVPEGGQIGARPAPPIHMGSDYADVVERGILSAEKAAELFERYNTLMAPHMPAVVFPRGATAEETRRAKPLLFLAIMAASSSESPNVQRRLVKELMQIFAEKIIITGEKSLEIVQALQVAVIWYWPPEHFEELKFYQLVHIGAVMALDIGLGRRTAGRKMQIPYQWRNHPFKRAPPPDPTTSECRRAWLAAYFLAANTSMALHRPNLVRWTSFMAESMEALQTSADAAPSDKYFCHLVWTHRLAEEVGIQFSMDDPAVVPNITDSRTQYSLRMLERDLEKYSASVPKEEMQSTLKMSFHVLSLYMHEIALHTQMDDIRPPFDTATLKDGMLTNLTLTTSHINALSACLSAIDGIFEAFLAMEVPSIRCLPVFNFVRVAYAVVVLIKMYFSATAPGSELGRVIDKDNMKVEYYLDALLEKFRAAASDDRSRPAAKFLIVLVMLRSWFLKQSKGLAMGVPVPEAATAGFKSSNSQPETPASAAAAQPSSRRPEATSASTAADEQQHQAQQRVYAGQQHPPMQEYPAANTPLHLLSEIATQNDRSGSGGGGGATNNILWNPPPSRQSFLYDPSAVTPTPMDGPGSGPGTAASSGTAATTVAGPGDGSGAGTGAGPGPNSVAPWLNPVWTNDLQDFGLDPGFTNDLSLEEITTGFGTSPGSLSNGMRYVMAQDPWLSGMSGLGEIFEGMPGGSGPPMFPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEM7</accession>
    <name>A0AAD8XEM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_731188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364492.1">
        <property type="nucleotide sequence ID" value="XM_060512863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEM7"/>
    <dbReference type="GeneID" id="85396761"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="43961" checksum="F6E978935121DCBD" modified="2024-05-29" version="1">MSDATDKEVVPPSMDSSEKPAGLPKPKDVQISQVNKRSGAFSWPSRFFLRENISVSWENSPFIAEDLKSTTAELEGDDVGFMLSTEENWAPDRYRIDCILDIVREANLKKLREGDEGAQRDKIALLIDGNNSGARPSFRKFLGGLNAQELYEELRKQCQGPLIHTDGIYATTMRCMVTGYDQWRWTGLVLVKTWFDEILDDPSPDMKTGYENDFQDGMISDPLWRRKDDATRTEWSPRPYFIRVLEIRITRRHEDFMTHARVPAKEPQEFHKRQGQFLREFDEFERGFGELKGILEELAQDLKETVRSGEFFMNTDVRYFINYDESEDESLCVLHLTQIRNTFNILEQLGMRLRDMQQKCRDLMDEAVSARKIPSEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGA9</accession>
    <name>A0AAD8XGA9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_628935</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362470.1">
        <property type="nucleotide sequence ID" value="XM_060508737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGA9"/>
    <dbReference type="GeneID" id="85392636"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10004">
        <property type="entry name" value="RPD3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="97"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="466"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="479"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="571"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="660"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="702"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="739" mass="81613" checksum="FBA0C203A2C40DB9" modified="2024-05-29" version="1">MSRAALGNLGPSRSELPRAAFTPFTFFPILPSYRPPQSVSPGPHIHIADDITIANRSPTDAMSQLGSVALANGSATPKKVAYFYDSDIGNYAYVTGHPMKPHRIRLAHSLIMHYDLFKNMEIYRAKPATRGEMTQFHTDEYIDFLQKVTPDNMDAYQKEQGKYNVGDDCPVFDGLFEFCGISAGGSMEGAARLNRQKCDIAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLRFKKRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGELRDIGIGTGKHYAVNFPLRDGIDDTSYKSIFEPVIEHVMKFYQPEAVVLQCGGDSLSGDRLGCFNLSMEGHANCVGYVKSFGLPTLVLGGGGYTMRNVARTWAFETGVLVGKHLPKTLPYNEYYEYYAPDFELNVRPSNMENSNSFEYLEKIKAAVIDNLRHTQPAPSVQMQDVPRQPFGGMTDEEEAELNDMDEDENADDRMTQRRWDQRTRNEAEFEDSDDEDMDQANGMTRPRNAKKRTFGDYRQAEGEVDSGAPSPVNGAPEGEEAPNAEPIVDADITLENPAEPEDTSDKTVPEKEAASEASKEDAVDEDGDVGMEDGADVEEGTTTIKKEEVEAEPVPVAEKEEKTEKIPSRQPSANPATEPPVAETTETTEATDAAKESAKETETAASKETEVTEANESKPEVAAEEPAAEAKATTPEKEKDTTEKPEAKAAEPEVDKMEVDEKPAEEEAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGM8</accession>
    <name>A0AAD8XGM8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367314.1">
        <property type="nucleotide sequence ID" value="XM_060513899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGM8"/>
    <dbReference type="GeneID" id="85397797"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041972097" evidence="1">
        <location>
            <begin position="29"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="15646" checksum="B6BC580595B12ECA" modified="2024-05-29" version="1">MVSLSLLAPSKVASALVLVLGLADMCNAAVQCDIITSVNCGKAKHHLGHKLPTNVGSTYYVDGFHGGVMNAKFQSMVNSVPGNSEFVDLTYNFNLGNYDRAYWVLLPTSFGGANECFAVYKNCDVTIRFWDKKDPLPNWYTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHE9</accession>
    <name>A0AAD8XHE9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_717245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368154.1">
        <property type="nucleotide sequence ID" value="XM_060511927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHE9"/>
    <dbReference type="GeneID" id="85395825"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="3">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="34345" checksum="2DDB85F16C01DF4E" modified="2024-05-29" version="1">MSIPDDTSPYAALPTSPKRAAQDDLATEPESHPPATKRSRATSPSQDDDDDSEAKTRATTAAMANASLTAGEGECEGEQGVGEGSAAAEAPAAQTTQTQPAADETPETTIQPPPSAPKTKTCGVCHEKEGKYKCTRCALPFCSVPCNKTHRENHPPDPEPAPKPPSAAIEPPAPSSAAAAASDPRNPFSVLDDSDQLQYLFRRYPTLQARLLEIFAATEPPPELQSTGSSLNDMMKARALAAANPKKEQWTHDVGIRKGKEALRRARAADGEDGEGVREYVELINHLMSQASAAAEAEEVIRKQAAEKDAELIRRLMTEDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHT6</accession>
    <name>A0AAD8XHT6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multicopper oxidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_577095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365273.1">
        <property type="nucleotide sequence ID" value="XM_060504985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHT6"/>
    <dbReference type="GeneID" id="85388884"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF71">
        <property type="entry name" value="OXIDOREDUCTASE TPCJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="117"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="303"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="517"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="702" mass="78475" checksum="75B86C0BF87029E1" modified="2024-05-29" version="1">MLALRHVWIIVTDVANSLFGSPFFRDGPQHHLGAKFSWPHTGLETAGHGSPVFTPPGSNIDKFVCDYSQMKGFKPCGTAEDRSCWLRNSDTGEEYNITTDYEDKMPQGITRAYYLNVTDGYINANGLNFTEAKLFNNTWPGPLIEACWGDTVEIHVQNLLVNNGTSIHWHGIRQNQTMQMDGVNGITQCPIAPQSSFVYRWNATQYGSSWYHSHYSVQYADGLQAPITIHGPTSFPYDEAIEPISVTDWANNSAFENMYTAATGQDILLGGIGNITRFTDGGIDNITEIPRGYEIWFDDIEPNHLTRAKRYLLRLVNTAYESTFIFSIDNHIFTVVEADFVPVEPFNATSILIAIGQRYHIIVEAKPTVNHDNPDANPLPEDGNFWIRTQVPLQEGTNRTSEGNATVDVNNYMKTGILRYDSSSTADPTTTGWNISHIVSDTEFNDKLVPTVPWTVGPPSNGYVGEQFDIADLHNAAMKSGPYATAFFSFERPDSEEMRPFQTTYGNPTFLNLDNVGDEWPTGWVVVPENYTADDWVYLVLNSNNTDITHPTFGPHPIHLHGHDFAIIEQEDNKLWSKEDFNPNMVKTKNPPRRDVVLLPKNGYAVIAFKSDNPGVWLMHCHIAGHASAGLSLQIMERQADANKIWPAGNSQALDNAHNLCASWNTWAYDCKNYWPGNLGTDENPDYPACANATNLQNDSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIG2</accession>
    <name>A0AAD8XIG2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_546056</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for methylating the 5'-cap structure of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368617.1">
        <property type="nucleotide sequence ID" value="XM_060503447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIG2"/>
    <dbReference type="GeneID" id="85387346"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 15" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="17">
        <location>
            <begin position="110"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="119"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="15">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR028762-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1728562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="455" mass="51634" checksum="D3946098425006EB" modified="2024-05-29" version="1" fragment="single">NGNSSRRGNKREDGTDELPQPYNAKELQPAKRRAVSPSEQPRKQKRPGARARISETEREAIRQRALDREKELEAAAHAAAERQRGTNNDVVTQHYNSVPERGRDWRRTDSKIKGLRAFNNWIKSCIIQKFSPDEDYAPGSREPGAKELLVLDVGCGKGGDLGKWQQAPQSVELYVGLDPADISIDQARERYRQMGSRGGGGRGGRGGYRRPPPRLFEARFQVKDCYGENIEDVEIIRQVGFDTSPLSRRGFDVVSMMFCMHYAFETEQKARTMLRNVAGSLKKGGRLIGCIPNSDVLGDHVRKFNEQQEEKKKKAAEEPPQEAEEGELEDGEADQSAEWGNSIYRVRFPGKTPADGVFRPAFGWKYNFFLDEAVEEVPEYVVPWEVLRALAEDYNLELQYHKTFMEIWDAEKDDETLGPLSERMGVRERGGGRLLVSPEELEAASFYTAFCFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XII0</accession>
    <name>A0AAD8XII0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron permease FTR1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_575091</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366158.1">
        <property type="nucleotide sequence ID" value="XM_060504778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XII0"/>
    <dbReference type="GeneID" id="85388677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="37805" checksum="8D530D5A766353AC" modified="2024-05-29" version="1">MEDLFSLPIFFITFRESLETAIIVSVLLAFIKRTLATKDDPVLHQKMVKQVWLGTAAGLVTCVVIAMAIISGIHSLGAEQFAAAESIWEGIFSLGASLIITAMGAVLLRVTKLQDKWRVKLSKALNASESHSGPFRDRLKYLGEKYALFLLPFITVLREGFEGVLFIAGVGVSETAASIAISSILGLALGAFVGYFIYKGSKTAPIQIFLIVSTCFLYLIAAGLFSKGVWHFEQNEWNKIVGGDAAELGSGPGSYDVRRSVWHVNCCNPDLNGGGFWGIFNAVLGWQNSATVGSVVSYNLYWVAVAAGFFAMICNEKGYWPFAGSKAKKLADEHEGDDQEPLLSRPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XII1</accession>
    <name>A0AAD8XII1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368692.1">
        <property type="nucleotide sequence ID" value="XM_060510195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XII1"/>
    <dbReference type="GeneID" id="85394094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042290706" description="Secreted protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15724" checksum="C9CA5F92705CD9F0" modified="2024-05-29" version="1">MIVGKMTLARIAARQFVGLLLLRSVSVEFGWHVSMGLIHSGTSIELKASYNVGFGGYMLRAPRARDCLETHQMSGIREEASGTTRHQRRCLSEWACWANYGLRCLESGVFLIEKLACAGSGHGRERMYWEQATSIGELTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIL0</accession>
    <name>A0AAD8XIL0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368812.1">
        <property type="nucleotide sequence ID" value="XM_060513681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIL0"/>
    <dbReference type="GeneID" id="85397579"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="678" mass="75773" checksum="81B8A8521E00169B" modified="2024-05-29" version="1">MAAHQTPFYCLWQKEHAHLGAAVLDLLPKRDIAALRLASPACCNIATKPLFKRVRVTFSANTFTKQSRIQALARVGHHIEHLHFHFAHTDATFLPPLVHPTTGREISFLYTPHTSMASVLARPKYANTELGEILTQQYPPLFHAATNVPSFINALRYLTNVRHLTIRCPGQDPQERYRRDIVDYAIMSLRIAVERAPLERLEKLSLSGMHPSSFNYLRHVPGFGAAPSAGRRWKQIRKLNISVEAWDFYGPSPGLDHLKIMDDYIRQFSGTLEKLHFTWLGPKGPCPIALSADPLFAPPKHSKKLFAEVTSPMSPLPPAPARKPMHFPRLRYMQVRNATMTAAQLSDLVDAHQKTVKEFDFDNVVLINGGDWDEALAPLMEKNPSSSSSGHGHGSGSDIWSQHSRSNSEAGSLHSDPEPYHDDDLPSPSAAAAAATRELLDFDLGSELYVDEELFDPYDGLDEDLASDLAAAKEASTSFSTVLKKKRVHRRRKHRKDNSDKSNNKESSSSKESPSRHHRSRKHKHHREQPPVPEEDDVFRPSTPVPIITAPIQDMSPHPVLLQPAVYDPNASRLSDPNDGISSVQRNIEQEEAHRLLAEDAAMRVSALRKAKAAVLMKLSREFNHRKGSPAPVANKDSCGLQMRLREGLFGRSFVSVLPDDRSMSSQSALVPLMFTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ2</accession>
    <name>A0AAD8XIZ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="10">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_614319</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366968.1">
        <property type="nucleotide sequence ID" value="XM_060507827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ2"/>
    <dbReference type="GeneID" id="85391726"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="68"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="306"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="474"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1726913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="56552" checksum="57A9D857B8F12C6E" modified="2024-05-29" version="1">MLSRSFIPASEQKNLVAYTPMFHARLYKDTENYRQCHFQAVRPGDSNDATDTAMNPTTTKPWLDGNPAIDRPLFVQFCANDPDALLGAALKVAPYCDAVDLNLGCPQGIAKKGKYGAFLQEDQDLIFKLINTLHKNLPIPVTAKIRILDTRAATLAYARNVLAAGASILTVHGRLREQKGHLTGLADWETIRWLRGQLPPETVLFANGNILQHADLQRALDATGADGVMSAEGNLSDPAIFSRPPEAGTETREYWRGKDGKGGYRVDAVMRRYMDILHKYAAGQDPPSRRPLFVPGDDTAWMEEMDRAEAEQDEPERKKRRRDVTNGPKSAKSRALSPNYSAMQPHMFHLLRHFVSKHTDVRDLLARSRAGDLEAYERILSMVERKVAEGLIEYEARGAEMFAGDEVLGPEADAAEVVEEDGESSRGAVKRCKRPWWVVQPIIRPLPKEAMAKGAVSLSKKDKAKLKAAGNGETAREEGKEEEVKKNGEKEDQSVQEKVLETDDKLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKI9</accession>
    <name>A0AAD8XKI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosome segregation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_716525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369112.1">
        <property type="nucleotide sequence ID" value="XM_060511855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKI9"/>
    <dbReference type="GeneID" id="85395753"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033551">
        <property type="term" value="C:monopolin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990644">
        <property type="term" value="F:microtubule site clamp"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045144">
        <property type="term" value="P:meiotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23787">
        <property type="entry name" value="RWD_CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.80:FF:000001">
        <property type="entry name" value="Chromosome segregation protein (Pcs1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040349">
        <property type="entry name" value="Csm1/Pcs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020981">
        <property type="entry name" value="Csm1/Pcs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038608">
        <property type="entry name" value="Csm1/Pcs1_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28006:SF1">
        <property type="entry name" value="MONOPOLIN COMPLEX SUBUNIT CSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12539">
        <property type="entry name" value="Csm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Monopolin complex subunit Csm1/Pcs1 C-terminal" evidence="3">
        <location>
            <begin position="349"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="455" mass="49432" checksum="DDD2B151DE8C5E28" modified="2024-05-29" version="1">MSPAKKARGRPPSANKVTKPAQTATKGRAAGKLAAAISKAGEEAINDTSSKTSGRVSKRGRKAVEKIAIQEDDDVEDVDEEEDASNVDSMAESEEDTAPVVTATTAKTRGRPKAAATTATTTDSSKGVPNSTTKDTTKSTKRGRGAGAKVTRSDESEIPETQAQDVMDVDTEGDDQFEELPVPKPSTHRGNRTSGNPDLDASDVQIRRRLGDTIRKYDNLEAKYRDLRDIGVKAAERNFDNLKKESEERAKTANELIAHLKADLTEQRSLAKEGQQRKKQLEEMEAKVSVLTTSLADAKQEIKTLTTRLAASRSAEAAASAKVIPGSAVKGSSAAARAIASADVVQTGQLKEDLYGDLTGLIVRVTKRDSAGQVFDCIQTGRNGTLHFKLEVENESSGENYEEAHFTYKPQLDSNRDRELIDMLPDFLVEEIEFPRPHAAKFYARVIKSLTERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKK9</accession>
    <name>A0AAD8XKK9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_66013</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369133.1">
        <property type="nucleotide sequence ID" value="XM_060511055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKK9"/>
    <dbReference type="GeneID" id="85394954"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000077">
        <property type="entry name" value="Probable chitin synthase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF46">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="694"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="776"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="787" mass="89268" checksum="907E0A6C8809BB2A" modified="2024-05-29" version="1">MLAAILEWFLWIAAFLYCLWKVFVKAEHWSIRVLAVIVGILFTCFRAIFLPIMIVTLPLPSAVVKYWPTNMVDVLQWFAFWSFAGLLTIPWLFCVYQLVTNQLGRTKRIKQVLDEVSAPKVVIVMPVYKEDPDVLVVAINSVVDCDYPPSCIHVFLSFDGDQEDELYLNTLEKLGVPLTLETYPKSIDVSYKSARITVSRFPHGGKRHCQKATFKLIDKVYEHYLKRNDNLFILFIDSDCILDPTCLQNFVFDMEMSPGNPRDMLAMTGVITSTTKKHSLITLLQDMEYIHGQLFERTVESGCGAVTCLPGALTMLRFSAFRRMAKYYFADKAEQCEDLFDFAKCHLGEDRWLTHLFMIGAKKRYQIQMCTSAFCKTEAVQTYRSLIKQRRRWFLGFLSNEVCMLTDWRLWKRYPILVLVRFMQNTIRTTALLFFIMVLAIITTSKKVDNLPVGFIAISLGLNWLMMLYFGAKLRRFKIWLYPIMFILNPFFNWFYMVYGIFTAGQRTWGGPRADAATADTETTAQEAIEQAKEGGDELNIVPETFIPAAEARKESIAGGKGNMGPMGRKHSVVQPPSQIEGRFAARKKSAAGFYVNADDSQVTVNRSGPSGFGPAWALQSRDSFDSMVSSQTAGNSVYMPRRVESIMGEEDRKKYELAQQSQFNQFLSNSKRFGAQTTTTGQVYEYSDAEMKRGGFQDVPDPMDRGQEYTDNVRMGSVDNSFSGRPQSGEGLPRQGMNATHSARGGRSPLARASLVRTIPLEDVQSEGESSSGGHDSRDDSPKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKQ5</accession>
    <name>A0AAD8XKQ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_569065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369233.1">
        <property type="nucleotide sequence ID" value="XM_060504147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKQ5"/>
    <dbReference type="GeneID" id="85388046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="151"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="324" mass="34972" checksum="3D9F6A7C8FA9C66E" modified="2024-05-29" version="1">MSSLEAKIVVLGSQNVGKTSLVMRYCKGAFNPAQTTSTVGASFMTKRVVDSDTDTVVRLQIWDTAGQERFRSISRLYYRGANACILCYSITDAQSFTEMGVWLTELRRNLPGDVVLHVVGTKADIVARDPSRREVPFERCIAYVAENLAPGLASTPPPTATSSGMPSLLSSSDPRQSSSQVHQSTSTFGGGGPSGGEPRSPSSKRSSGFWGQEVGWDACHEISAESGEGVEEVFRVVTRKLVEQNRKMQQALLLATATPGTPGYETGMDGGYFDGMNPRGSFRVGRDRRSWLFSPNFSPAVTVEQGGTEQDADEGAGKSRRKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKX0</accession>
    <name>A0AAD8XKX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate/quinate 5-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_716415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369338.1">
        <property type="nucleotide sequence ID" value="XM_060511850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKX0"/>
    <dbReference type="GeneID" id="85395748"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="40780" checksum="C4B51D3E3087EA82" modified="2024-05-29" version="1">MAFTVLSDNNVKQLFQGFGPEDVALMSDVLTDAFLSYSVGPEAQYQPHRAAVVRPDGTTGLFMPATMKGGMSVKVVGLPPPNSAVSDLRCVLTICDGTGKAVGIINAEELTAFRTSLGSILLYRYRQATANIIVFGAGKQALWHLRLALVLRGKDIKTITIVNRSKERPAKLMERLQAMSKASGVGNTDSVTFTVIEATPDSAPGNAELCTAVEESDVIFCTTPSTQRIFPAEWLTSERGSAKTRYISAIGSYKLNMKELDPDFLRAVVDTPLGAFTSAEGGAKKDGVIFVDSREACFLEAGELVEAKIPAERIVEVGEFTDELRKADEGEAVLLREWLEKGLIVYKSVGIGIMDLSLGKVILELAAKHKVGTILPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL33</accession>
    <name>A0AAD8XL33_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HMG box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_568623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369447.1">
        <property type="nucleotide sequence ID" value="XM_060504094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL33"/>
    <dbReference type="GeneID" id="85387993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="328"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="398"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="54596" checksum="BF5E2D51BD565881" modified="2024-05-29" version="1">MAQGLDRIFAELGISQYLDIFLEQGFDTWETILDITESDLDALGVKLGHRRKLQRRIANSRGLAPDASLVSPTRACAEEPKPETQRLDQPRLEVKEGPVATKRKYRRHPKPDENAPERPPSAYVLFSNKMRDDLKGRNLTFTEIAKLVGEHWQNLTPGEKEPYETSALKAKEKYNHDLAEYKKTTEYRKYNLYLQDFKARQASANQAKESSKRQKLDSGVRLQNGGSASATPGSLSSTGSGTESHQGSEPPPNRKQRVGSVVSVSESQYSTAVPTPISHHHHHNDDSVHSPASVQFDGECLQSTTPVKPEPVTLPHLPSLSDVFSNGRGLNGVSRSPEANGFGGFAPPTHPGPSAPPSLKHEYSSAGSISSSGSGLSYPRTPSESSLPIHALLSNKTLPGPPFELQPSPFSTVPPAGPPPLQDSKLPYAGQPQAPIGATNGTHGYQSPPALLRFQSTSSTGTDGSNVSQASSGASSATSLGVQERSDPKLDGMSALVRAGEIVNGRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH2</accession>
    <name>A0AAD8XLH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BDZ83DRAFT_568332</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369625.1">
        <property type="nucleotide sequence ID" value="XM_060504053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH2"/>
    <dbReference type="GeneID" id="85387952"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000007">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0749">Sporulation</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="22">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="20">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAK1729570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="151" mass="17128" checksum="656B490E4C1E6269" modified="2024-05-29" version="1">MSTAARRRLMRDFKRMQTDPPAGVSASPVPDNVMTWNAVIIGPADTPFEDGTFRLVMQFEEQYPNKPPAVKFISQMFHPNVYATGELCLDILQNRWSPTYDVAAVLTSIQSLLNDPNTGSPANVEASNLYKDNRKEYTKRVRETVEKSWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMU5</accession>
    <name>A0AAD8XMU5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_602218</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370331.1">
        <property type="nucleotide sequence ID" value="XM_060507149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMU5"/>
    <dbReference type="GeneID" id="85391048"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000067">
        <property type="entry name" value="Transmembrane domain transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="685"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="357"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="760" mass="82541" checksum="BF499E24CA208A93" modified="2024-05-29" version="1">MASPSRDPLSIPRADSPSRQFGSLPRADATARLASPVPSQQYGTPQTGRFVGSSSRLGDASETASLAPLAGAAPSSVQGPGVSALAAALSNSLGTSPPRHGTPPVRSATPPARPLSPAAAGAQLSSTPMTNYGSFDSRSRNAGAGAYEDPEIVKRHLVQPTDAASEESSMRDGVKGKQTVSADAETGLNEDEFSSLQLQGGDVTRGIYKWTEEAEARNKMQRSKSFSVSRPDPETDILDINTIKVPGGFRRNYLRRAARSPSTARDGGERGEASEASQPRLLTSSFLEFLSIYGHFAGEELEEDDEALRPGEYFSSGEDMYESDDESDDDREPMEDSALLTPSRHRRRRKQRGGSGKNSPMSAALLLLKSFVGTGVLFLPRAYLNGGMVFSNAVLLGVAALSYYCFVLLVTTRLKVDGSFGDLGGILYGKWMRATILSSIVISQIGFVAAYMVFTSENLQAVILAVSDCKSNIAVKWLILLQVLVFLPFSLLRDIEKLSFTALIADAFILLGLAYLLYYDILTLATNGIADIIQFNRNDWTLFIGTAIFTFEGIGLIIPIQESMKNPSKFPRVMLAVMIIISVIFIGMGAISYAAYGSKTETVVLLNMPQDNKAVNSVQFLYSIAIMLSIPLQLFPAIKITENALFTKSGKYNPYIKWQKNLYRFFFVILCAVIAWGGADDLDKFVALVGNFACIPLVYIYPPLLHYKAVARNRLWKISDIILCIFGFVAMAYTTTLTVYSWAGGSDGAKPPAYCDRRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN78</accession>
    <name>A0AAD8XN78_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydantoinase B/oxoprolinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_566400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxoprolinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370568.1">
        <property type="nucleotide sequence ID" value="XM_060503845.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387744"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049517">
        <property type="entry name" value="ACX-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19278">
        <property type="entry name" value="Hydant_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="244"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Acetophenone carboxylase-like C-terminal" evidence="5">
        <location>
            <begin position="641"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="743"/>
            <end position="1265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1297" mass="138279" checksum="72AEE58BA495646C" modified="2024-05-29" version="1">MGSLPGPVGGIRISIDRGGTFTDCVASVPGQDDILVKLLSVDPSNYPDAPVEAIRRVLEKATGKEYPKGRKISLRGVESIKMGTTVATNALLERKGERTVFAVTKGLKDLLHIGNQSRPKLFDLAIRKPDVLYSKVIEIPERVTLDAWSENNKPEPIDVSSDSALVTGVTGEAVRVLEPLDLEASRKALQEAYDEGYRSIAVCLMHSYTFRDHEAAIAQLAADIGFTHISPSAELSPVVKIVPRGNSSTADAYLTPEIKRYIAGFESGFEDLANSGCRCEFMQSDGGLVEFSGLSGLRAILSGPAGGVVGYARTCYDDADKTPVIGFDMGGTSTDVSRYAGELEQVFETTTAGVMVQTPQLDINTVAAGGGSILSWQSGMFKVGPESASAHPGPACYRKGGPLTVTDANVVLGRVRPEFFPKIFGPNEDLPLDVDASRRLFEELTANINKDEGTALTVEQAAAGFLDVANESMCRPIRTLTEAKGYDAGLHNLASFGGAGGQHACDIAKTLGISRVLVHKYSSVLSAYGMALADVVSEERSPCALTYTEANLATFASELDKLVEKAGDVLLMQRIPEERIMSERYLNMRFQGSDTPLMIQETAAAPGGGYLEAFKDAHQKQFGFLPVGRDVIIDDYRVRAIGKTTVQLPVPWPKELAYAEATAASPAKTTKQVYFKGLGWSETPVYGLAGLTPHTKIAGPALIMDDKQTIVVIPDAAATVLSETVVIDVAVGTKETISTTTIDPIQLSIFGHRFMGVAEQAGRALQKTSVSTNIKERLDFSCTVFSPDGGLVANAPHVPAMIGSMAFAVKWQIDHWGDNLKPGDVILSNAPVCGGTHLPDLTVITPVFNAEGSKIIFWTASRGHHADVGGILPGSMPPNSKELWEEGAVIKAFKVVEGGVFKEKELTDLLMAPAHSPGCSGTRCLRDNISDIKAQAAANHRGSQLIHSLIEDYGLDVVQFYMEEIQGAAERAVRDMLKTIHKRTAGKPLEAIDYMDDGTPIQLKVTIDPSTGGAVFDFHGTGPEAYGNWNAPIAICNSSIIFALRCMVDAEIPLNQGAIRPIDVQVPEASLLKPTEYAAVCAGNVLTSQRVVDVIFKAFGAAAASQGCMNNLTFGTDDPETGFGYYETICGGAGGGPSWDGVSGVHTNMTNTRITDPESLERRYPVILRQFCLREGSGGKGAHTGGDGIIRDIEFNIPIKVSILSERRAFAPYGMAGGEDGQRGRNVWVKKSGRVVNLGGKNTAMMDAGDRIVIMSPGGGGYGRPEDRVEGEAKPAAAFVGVANGTVDMIQSMGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN91</accession>
    <name>A0AAD8XN91_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_715637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370650.1">
        <property type="nucleotide sequence ID" value="XM_060511768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN91"/>
    <dbReference type="GeneID" id="85395666"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="9">
        <location>
            <begin position="42"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="233"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="57322" checksum="AA5CE9B7201F2FBF" modified="2024-05-29" version="1">MSGPRAVVPSLETVRSILASPATTNAAKKPTLVPVYRQISSDLITPSAAYLKVSAHHKDSDFSFLFESAATEQVGRYSFVGAGPRKVLATGPGHGPECDPLPALEAELAQHVVAHVPGLQLPPMAGGAVGYVGYDCVRYFEPKTARPMKDVLQIPESLFMLFDTIVAFDRFYGVLKVITYLHVPEDASQLEAEYQKATQTIDELIAVLNSPDIPIPEQQPIKLGQEYTSNVGQQGYESHVTELKKHIVKGDIIQAVPSQRFARPTTLHPFNIYRHLRTVNPSPYLFYVNCKDFQIVGASPELLVKSEAGRVITHPIAGTVKRGKTPEEDQRLADELRSSLKDRAEHVMLVDLARNDVNRVGDPYTVRVDHLMVVEKFSHVQHLVSQVSGVLRAGQTRFDAFRSIFPAGTVSGAPKVRAMELIAELEKEKRGIYAGAVGYFGYGGVDEKGEEVEGAMDTCIALRTMLVKDGVAYLQAGGGIVFDSDEYDEWLETMNKLGANMQCITTAEELYYDQQQQAAGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNG4</accession>
    <name>A0AAD8XNG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_373854</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370582.1">
        <property type="nucleotide sequence ID" value="XM_060502662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNG4"/>
    <dbReference type="GeneID" id="85386561"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="24523" checksum="1B1864EF0C0CC1CA" modified="2024-05-29" version="1">MVDLACRVELATSCCLWVLLRTSGRSIAFATNGQYRSFNPPTTSLGLTRRPYDSTAKFPGLQTETFRSDESHRHAQLSAPTCPVHHPQDSLSSQQVVSIRLSSQSASLRATPTGIATDVTCPHVIWPGASASSRGFCPMAPEDAKSTLIPPGPNTCPVMLLSREAPDESAVFYGCLLSARNALHCVLSTERKQKLVQGGRAIQTERVSRVLESTQTGIQFAEPRVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPE4</accession>
    <name>A0AAD8XPE4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565688</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371056.1">
        <property type="nucleotide sequence ID" value="XM_060503785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPE4"/>
    <dbReference type="GeneID" id="85387684"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="Hypothetical protein YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD-like" evidence="3">
        <location>
            <begin position="75"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="29"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="18588" checksum="DD1CAA48C9E0637C" modified="2024-05-29" version="1">MAANNDNTSTLKSYVDSATGAAQNLLGSLTGSTADQNKGEAKQDKAQLEHDASHATAKVPGFTATAGGVTKDDPDRAGGSWNQTVGSAKETVGGLVGSENLKQQGREQNLEGQQQEAKGQLNDYTSGIGNRVQGTIGGAVAGLTGDKAGQAHYEGLHDTGKTQQRGAEHDIQKQAEARQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQD4</accession>
    <name>A0AAD8XQD4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_564575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371680.1">
        <property type="nucleotide sequence ID" value="XM_060503656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQD4"/>
    <dbReference type="GeneID" id="85387555"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF3">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="63247" checksum="55E8E000422B8141" modified="2024-05-29" version="1">MPLASHVNPEDIVQRLQATHITAPGSANALSHGTSSHIQPYDSRYTSQTNIPKYKIPDEGAPGDTVFQMIRDELDLDGKPNLNLASFVGTWMEPNATQLMQENLSKNLSDADEYPAMMEMHQRCISIISHLWGVQPGEKAIGSATTGSSEAIHLGGLAMKRRWQLKRKEQGKDTSKPNILMGSNAQVALEKFARYFDVEARILPVSKKSHYRLDPALVRENVDENTIGVFVILGSTYTGHYEPVEEISQILDKYQEETGIDIPIHVDAASGGFIAPFTHAGAGGSKWNFELPRVKSINVSGHKYGLVYAGLGWIIWRDQSFLPEDLIFELHYLGGTEKSFTLNFSRPGAQVIVQYYNLIHLGFDGYRSIMENCLSNARILAQSLEATGWYTVVSDIHRRAPHKEASGAVKKIVNQAATAVGGESAAPGETSADYVAGLPVVSFRLTDEFKAKYEHIKQETVSLMLRAKGWIIPNYPLPPNEEKIEILRVVVRETMTFDLLERLLTDIVEVTETLIENDQIDLQVLKKHHSRRRVRVKGDEEKHKKAGAAKGVEDGVRKMEDGIHRAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQN5</accession>
    <name>A0AAD8XQN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_597309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372015.1">
        <property type="nucleotide sequence ID" value="XM_060506897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQN5"/>
    <dbReference type="GeneID" id="85390796"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="82" mass="9635" checksum="2B45E61D3F1BF26D" modified="2024-05-29" version="1">MQIIVLFWDIWMLLISLILYCSPRASTYARCHFNETNVLRGSSSESLSSTLIQYSTRLKIMILTHSLLWDMQNPSPTKIWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQP2</accession>
    <name>A0AAD8XQP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371743.1">
        <property type="nucleotide sequence ID" value="XM_060503570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQP2"/>
    <dbReference type="GeneID" id="85387469"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="23798" checksum="11B7314E213542DE" modified="2024-05-29" version="1">MELPFGSLRSRKSTPWMNGRLQPIDQFPGNYQLRTKSDPHPSATTPHPFSRPVFGSPQDLPRIPLCTPYTPPCVGHACVSPTPPTPLDRGTLTSVTTGLMQLPLNLSRPGKRICVTTNRGVISCSEVVSRLGLLLPPSPSSPSLRAGPRSQELGSARNYQQPRNNPLYFVIDCYTPYAVFTDIPPCNNTNLSLVHSTPFSPKVDYSTKPTETTIFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZK2</accession>
    <name>A0AAD9CZK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="16">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_716583</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="16">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="16"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369199.1">
        <property type="nucleotide sequence ID" value="XM_060511861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZK2"/>
    <dbReference type="GeneID" id="85395759"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000004">
        <property type="entry name" value="Acyl-CoA desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001522">
        <property type="entry name" value="FADS-1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00476">
        <property type="entry name" value="FATTY_ACID_DESATUR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="15 16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 16" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16" id="KW-0408">Iron</keyword>
    <keyword evidence="4 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="18">
        <location>
            <begin position="350"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1729144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="477" mass="53859" checksum="EB41E556625ADB12" modified="2024-05-29" version="1">MSATTSSSDAKVTKAENFPDGTSDYVPTRAKAYDIKKPHISTQPITASNWYKHVNWLNTTFILIVPLIGFICSYWIPLTWKTAVFAVIYYFNTGLGITAGYHRLWAHRSYKASLPLRIYLAAVGAGAVEGSIRWWSHGHRAHHRYTDTDKDPYSVRKGLLYSHIGWMVMKQDPKRMGRTDISDLNEDPVVMWQHVHFIKCVLAMGVIFPTVFCGLGWGDWLGGYVYGGILRIFVVQQATFCVNSLAHWLGDQPFDDRNSPRDHVITALVTLGEGYHNFHHEFPSDYRNAIQWWQYDPTKWCIWTWKQLGLATDLKQFRQNEIEKGRVQQLQKKLDQKRAKLDWGVPLEQLPVIDWDDFKAQAKNGRGLVAIAGVIHDVTDFIQEHPGGKALISSALGKDATAIFNGGVYLHSNAAHNLLSTMRVGVLRGGCEVEIWKRAQYENKDMTTVTDSSGERIVRAGDQLTRVAVPVASADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0Y4</accession>
    <name>A0AAD9D0Y4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369665.1">
        <property type="nucleotide sequence ID" value="XM_060513550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0Y4"/>
    <dbReference type="GeneID" id="85397448"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="42193" checksum="263DC00B60E43990" modified="2024-05-29" version="1">MFRLATAPGRTCGVSRHLLAGLSMPVSLPWPPAVPSSPPTTTPTTTTRTLKTKSKLRPLPGLKKSSAREEKPKPRDVVFEPRSLTEFKILLRELSYMNVTPERAYDVYMKYMKALARPDKPQDWQKAFVRENNITAGELHETAGLLYFTKNSSESEVILQFNMMETAAGLGYDPAALTLGRHLYRAEGKKNYYDWDNPRWQHTRTRCLALIAAGRDANAMVVAGLRHLHRKTERDDYLALEAFTQALALGKDAAYFDWMCSALEGQGDAYLRLGEKEKAKDTFFYLGKLGYARGWSRLADMYPDDKGAGGWLFKAAGAGIPGSYQKLVDHCEKWRKFCAPDKEWAAYWERHASEWTRILKASIARKKLNRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D165</accession>
    <name>A0AAD9D165_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear protein Es2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_603840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369934.1">
        <property type="nucleotide sequence ID" value="XM_060507245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D165"/>
    <dbReference type="GeneID" id="85391144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019148">
        <property type="entry name" value="Nuclear_protein_DGCR14_ESS-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940">
        <property type="entry name" value="ES-2 PROTEIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940:SF0">
        <property type="entry name" value="SPLICING FACTOR ESS-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09751">
        <property type="entry name" value="Es2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="446" mass="49352" checksum="B63F9BB8BC99394E" modified="2024-05-29" version="1">MERQERKSTALVRKRTDLELMPPPPAAKKIKRPKKVIDEDTYTDALSQIIARDFFPGLLEAETQQEYLDALESKDKAWISNAGQRLERVMTPGRNKVKRPMPFNNAGRTPSAYGADTPVSVASTVSEAPKPAVDTNMSLANFQATYTSEDNESFYKLMDKQNQKKAEKYEWIWRGNKLPSKQMIKQAEVEAKLLETRGLVDDGWKRDRLAIKDVDDRPARPDSWNANPKNNLMFGPDGVDDDYESPAQKAQAQSMMPPKAINYQNTRVPQPSIAERPPSPTLSAVRDAIAGKPRKEDLASSAVGGGETPRVNGYAFVDDEDDDEQVLPVPVINLGPGDATPNPFRLQEHRKRETLHHRLVERAAHSKRESVKNGLTGKLDRTPVPKFPSSPRVSGGLTPAAQRLWGKIGSPRPGSPHNSSLKATPMRARGSLLKGGASVTRASTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2F3</accession>
    <name>A0AAD9D2F3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_787452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371402.1">
        <property type="nucleotide sequence ID" value="XM_060515666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2F3"/>
    <dbReference type="GeneID" id="85399564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="56505" checksum="EB1B3EA86A7DB419" modified="2024-05-29" version="1">MANSQSSLLSTASSSVIDFIAAPPLEMSALIFSHLDNCDLKALQLTYPRLRHLDEDLYDSDDSDDEDGRPEKPPRGVTFWYFRHCKDNIEYLEIRQDYDAETLHQHLETAKQLEFQLPLDIAYTHYQGLLAEQNKVLSTSADIAAFEWALEDDRFPSLRRITLTPAAHGILFHPLYPTPDIRALPYGFNYPLPRGWPVPPKDGDKAMYGDWKSEDYKECWRGFRHVARILARQKSTKIEELMIDGNQLWSGFACSIFYAPEPCVEYDNLIAAIKKPGFTTLRLSLIRRTCDTFLSKLARTTISKTGTYPSHWVRDHFIPLRSVVPVETWKNLAHFGLTRWLVRQSDLLDFLAALSQTLRSVELSFFSFMKGHGNYRELLFAIRDTLGWQERTASTRPHLLIRDFPGVPLAGRAVWVEDAPQRFLYEDGENPYPIPPRNAVVTGQTITWKPGSLTVGHGFGTEIDALEPRFERPYESADKLIEMGISRDWKGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3D7</accession>
    <name>A0AAD9D3D7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_565221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371451.1">
        <property type="nucleotide sequence ID" value="XM_060503726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3D7"/>
    <dbReference type="GeneID" id="85387625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF5">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="732" mass="81226" checksum="1096F3C1966A5D3E" modified="2024-05-29" version="1">MASVSSRGPTPHSPYDVQSAADTEESWQYLDYASYPASVGFLPSPASGSLNGFAVVGHHAGSDPAGLSPLNLDLDQPAFSASSFPDQAEAFAAPAPSVDSQFVPSGQEANFLTPQGFLFAEEQLNLNELTSFVNSFQSNNASLADLDTFPQQQHDGDIDLSQTFPASINPGPWNPTNLKVDNGSSMFLMEDFSATSSQSSTSTSPSQSNSSSPDLKHEGDRAASASQIRKVITGKVEKKKATEPANKFVIVTPNSINASSGRPNPWECFEAMKIQTRGRKGPLANATKESALQVRRLGACFCCHSRKVKCDSQRPCKSCKKLAGQVPQVVCWQFSDFLTVLFPDFMRSHFRKDQMSKFMAENVDLDAVQLAPREVELFSGLSASLKVRARFFKPRTEEVQQHYHLHVQKDRVDLQARGSAPMVLELDSAAQREALRKKVKEYLAAIAAEPRFAKSVTESIRHTELPKKVLDVVQIYANKSDSSMVKKALAIYGAHFVMTRHLCITRQSVVGLQDSGLVPQEVPWVTPRVVNRQIKAVIDELLMRDMQHLFESFSKLLKPKSKQEWAPCMASFLVLCLFMESVETSADNFVVALNEISLRNHTPPEYKRQDALNINAAVENMPFKQFAYQFHQIYQTHSRDTANKPFNPMLDNSWAQQGDLDGPAIEMVLGLKNLIQQNGKELEGLADDPILSSDHEQHPFPRDVAANYTGRLVSKFLLSFMDEKHIFGENWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7L3</accession>
    <name>A0AAD8U7L3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_656960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000165">
        <property type="protein sequence ID" value="KAK1710906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358966.1">
        <property type="nucleotide sequence ID" value="XM_060510922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7L3"/>
    <dbReference type="GeneID" id="85394821"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="24639" checksum="A9D86ADD79796A90" modified="2024-05-29" version="1">MARYDELSRNLGQGGFVVDLQRRSWVLRQLKLGLQPSCGRERRRNPCLRVMNDLVSLPPGIKPEDIPIPSRGFSRVLFAIQALSSSAESTPLDSSLLRVQKYLTYPGLDKPDVIIVEQNRGFVTVLDLDRDLLFPGPPDLPVELNDMPSCVCYKVEHLFSTVFGVLDVNKDTVMDWRQYWNEFQRLLAKVNPLWKTEVTINNIRDLVHQCSFELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7Y6</accession>
    <name>A0AAD8U7Y6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_594072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000235">
        <property type="protein sequence ID" value="KAK1705924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357703.1">
        <property type="nucleotide sequence ID" value="XM_060506692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7Y6"/>
    <dbReference type="GeneID" id="85390591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8820" checksum="82BB9F915539DA5C" modified="2024-05-29" version="1">MGLERVEAVMRRLSINHEAEPLAGKVVSIIVAMISACLLASLFVMRWTSVKDWKALPWTMWRKEPSRLYAFVHDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8N3</accession>
    <name>A0AAD8U8N3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_798339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000340">
        <property type="protein sequence ID" value="KAK1701743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357052.1">
        <property type="nucleotide sequence ID" value="XM_060515927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8N3"/>
    <dbReference type="GeneID" id="85399825"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236198" evidence="1">
        <location>
            <begin position="19"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="29426" checksum="B089095ADF02F40B" modified="2024-05-29" version="1">MVSIWIAFFSAFVAAVSAAPTAIADKNNAALNITDTLDRNLRKGEIVVFGTGGRTAIITQDTWELLLKVEGIEAETPDIDHDFLRSGDEFSEISVNHTDLALGKRDCNSNYQTVVDRTQRFVDWDVQMSPVVIGAGSKGIDITISKSYSIANSVQVSAGIDLGLIKDRLKTSFGINYSRTWTTTQGYLIRGTVDNGYTGVVITRPWTNRKYGRTFQGCVGSLRQTGTFMADSHEDGSYEGVTWVGGAITACIKRQSSIPLSRCNGSGNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Z4</accession>
    <name>A0AAD8U8Z4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_595031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000268">
        <property type="protein sequence ID" value="KAK1704184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357391.1">
        <property type="nucleotide sequence ID" value="XM_060506756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Z4"/>
    <dbReference type="GeneID" id="85390655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1704184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="259" mass="28857" checksum="431AD1B20E495B77" modified="2024-05-29" version="1">MALGLRYIGGRHALALAAAIPCALLIKHGWEVYTSIRAVDTRRIVSSSGLSEHFRQSHTLKTLVNPRGHVSSADKLAMDMELPENARELSDEVLLATFARGFFAGKVLAIERRLLQTARPSFVSYAGLNSISMSNQIWKSQDFSCEKLPPVHSVVFGTFQLGYIKLIDPKESQAEPETESSVDFVFGKDNSQFAGAHRFSIVRRPENPANVRIVYESTACNPTRNQHLSGLLLRFHSLYAMLLFREGVSDILRRPELSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U938</accession>
    <name>A0AAD8U938_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_545071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358333.1">
        <property type="nucleotide sequence ID" value="XM_060503443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U938"/>
    <dbReference type="GeneID" id="85387342"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="95" mass="9929" checksum="643EFBD56F163F50" modified="2024-05-29" version="1" fragment="single">ADFGKCTPTIDFQLGRAGRKADEGTFLPTDALVAQGQQDALNPNIIINRVCDQLTNVCEANDAAKTQCLDAKAQILASGDKSAAVATTFNGLLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAB2</accession>
    <name>A0AAD8UAB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EC87 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358155.1">
        <property type="nucleotide sequence ID" value="XM_060514991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAB2"/>
    <dbReference type="GeneID" id="85398889"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932866" evidence="1">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="64" mass="6669" checksum="09390F73AF95B51D" modified="2024-05-29" version="1">MRAVFAIVSLLAATVAARFDGPCTDTVCGDSKVNCEAEGRICVGFPSVDPEKRLGCTCSIISIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAQ7</accession>
    <name>A0AAD8UAQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HAD-superfamily hydrolase, subfamily IA, variant 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_707764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360672.1">
        <property type="nucleotide sequence ID" value="XM_060511552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAQ7"/>
    <dbReference type="GeneID" id="85395450"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051400">
        <property type="entry name" value="HAD-like_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46470:SF2">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46470">
        <property type="entry name" value="N-ACYLNEURAMINATE-9-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27200" checksum="D1750F5230F0F0E8" modified="2024-05-29" version="1">MDGSNISSQVKVSLVDKPWFGFDLDDTLHEFRRASSAATTKTLEAISAKHGTPVDELKEAYGHVLRAKTAGAFSDGKTSYEYRRERFSSVLDRFGLPSDDTVFLEGLLDVYERTLNESLQLKDGAEALLQKLKSAGKKVVVITEGPQDAQERTVRALGIGGYIDFLATTNFFGVAKTEGLFGEVLRHLGIGAGEIVFVGDSVVRDIEPALGEGILSVFFDERGETSWEGRMMKVKSLRDLEGLIGDGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAX0</accession>
    <name>A0AAD8UAX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_535897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360762.1">
        <property type="nucleotide sequence ID" value="XM_060503355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAX0"/>
    <dbReference type="GeneID" id="85387254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="64"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="17291" checksum="2836CD11B6AD31DD" modified="2024-05-29" version="1" fragment="single">LLNFWLDECQKRHRDKCAYVGELVLEHEFASPTRLLRVGEEGENIVLVLSAGLKRDEGGFGPSYTALSHCWGDPKSVPQTTKANLEHMMRVGLRHDELSPTFQHAVKIARELNIGWLWIDSLCIVQDDKTDKDRELPLMEIIYSMAICTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB40</accession>
    <name>A0AAD8UB40_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_796429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359747.1">
        <property type="nucleotide sequence ID" value="XM_060515870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB40"/>
    <dbReference type="GeneID" id="85399768"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234515" evidence="2">
        <location>
            <begin position="18"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="408" mass="45398" checksum="6A94227F6E0F1789" modified="2024-05-29" version="1">MKSQLLLPAALLTLTHAATIPESAKPIIVPDSTLDAAIREPLQNFITGPVHGIDPSAFFPVVTLSENDEYKLAAAGEVAWAAIELEASAALAGSGSVSASDKGENLRDAAAVAVNSIARSGVPPPPHSDPPHREPHGHHEGITREQLCEYYKGIAWKTGDLQTAVYQWQYEYVPWLVHNKGPYIVVLDGLRHIEWVLWKIEQALVNAHFHYEDEFDILKCYQEYSGRELQITHVPTTAPALPTQTTANMTIGLPTNTMVHHPRALDEQLVTTTVTIQPARPTTLPPPGHPENNNNNNNNNNNNNNNNNRHEETGTSWPHLPWRRDHPSLKKLLRLITAKAPVSKYQSYANHRIYNVLKQLEYTALASANALRSKLRDPHHQSLLDYDIWKGQGINHAFEVAIAAYEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB49</accession>
    <name>A0AAD8UB49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_757967</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000193">
        <property type="protein sequence ID" value="KAK1708659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358341.1">
        <property type="nucleotide sequence ID" value="XM_060514965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002416">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="664"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="736"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="841"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1280"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1345"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1383"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1417"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1541"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="241"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="939"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="889"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="906"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="918"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1708659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1577" mass="177112" checksum="35FCF57E4073D376" modified="2024-05-29" version="1">MDEKPTPRDTDVPGGFPETPSLAPTSGRPTPMTLSSHGQHNAQNATFTQSSQITRSTTSYFATTSRIRDDTSSSTVTLSGNGLAVSGSRRASRTEYLSEKNAPIDDESAPSSPSANALSPTDSTHFAPLKTHISSTKRPEARRQGSNLTEDDLFRVLSRRRTNATHQSDAEQEEEQQEVERLMSRIFGRARQEQSEEEKTRHSGVVFRDLTVKGVGLGASLQPTIGDIFLGFPRKIKMLFARGPKAAFAKPPVRELISHFDGCVRPGELLLVLGRPGSGCSTFLKAFCNQRAGFQAVEGEVTYGGAPAEEMSKRFRGEIIYNPEDDLHYPTLTVKRTLNFALETRTPGKESRLDGESRKDYIEEFMRVATKLFWIEHTLGTKVGNEYVRGVSGGERKRVSIAEAMITRASVQGWDNSSKGLDASTAVEYVRSIRAMTNMAETSTAVSLYQAGESLYDLVDKVLLIDKGKCLYFGPSESAKQYFIDLGFKCPDRWTTADFLTSVTDEHERHIRDGYESRIPRTPEEFDWAYKNSDAYRRNIQDVEEFESQLHQQIEHRRQNETKKTETKNYEIPFHKQVIYCTKRQFMVMAGDRASLFGKWGGLVFQGLIVGSLFYNLPNTAAGAFPRGGTLFFLLLFNALLALAEQTSAFESKPILLKHKSFSFYRPAAFAIAQTVVDVPLVFIQVILFNIIIYWMSNLARTASQFFIATLILWLVTMVTYAFFRAISAWCKTLDDATRFTGVSVQIVIVYTGYLIPPTSMRPWFAWLRWINWIQYGFECLMSNEFYDRELQCVPPYLVPQGPNASPAYQGCALAGSPPGQTIVPGSSYIEASFTYSRSHLWRNFGFLWAFFFVFVALTALGMEHMKPNTGGGAITVFKRGQVPKKVEDSIAAGGRGKKDDEESGEASNSTQTMTADTAKKEKSDEDTMKQVARNETVFTFRNVKYVIPFEKGERTLLDDVQGYVRPGKLTALMGASGAGKTTLLNALAQRLTFGKVTGEFLVDARPLPKSFQRATGYAEQMDVHEPSATVREALQFSALLRQPREVSKKEKFDYCETIIDLLEMRDIAGATIGKVGEGLNAEQRKRLTIGVELASKPELLMFLDEPTSGLDSGAAFNIVRFLRKLADAGQAVLCTIHQPSAVLFEEFDELLLLKAGGRVAYHGPLGRDSQELIQFFESNGAHKCPPSSNPAEYMLEAIGAGDPNYKGKDWGDVWAQSKHKDERSREVDEMLERRKDVEPSKSLKDDREYAMPLTTQTVAVVKRSFTAYWRTPNYIVGKFMLHILTGLFNCFTFYKIGYASVDYQNRLFSIFMTLTISPPLIQQLQPVFLQSRQIFQSRENNAKIYSWFAWTTAAVLVEIPYAIVAGGIYFNCWWWGVFGWRLPAFNSGFAFLLVILFELYYVSFGQGIAAFAPNELLASLLVPIFFLFVVSFCGVVVPAAQLPTFWRAWMYWLTPFHYLLEAFLGVAIHDQPVQCESGEFARYQPPPNQSCEDYTAPYIQQAGGYVQTGDGGICEFCQYATGDEFGAGFSVYYSNIWRDFGIFCGFIVFNYAVVYVGTWLRFKGKNPFKKLMMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB92</accession>
    <name>A0AAD8UB92_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_586432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360957.1">
        <property type="nucleotide sequence ID" value="XM_060505948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB92"/>
    <dbReference type="GeneID" id="85389847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="30705" checksum="511B7CD0B076D2C5" modified="2024-05-29" version="1">MFWLGLLYRDQGRLDAAEELMSKVLDIRTSLMGEESEGTLRVMEALGHVYRTQGRLVEAEKLILKVLDIWRYTRGEEHKYTTPARGELGHIYKKQGRLGEAEYLFLEALDGWRTMKGEEHVHTLWAMGDLAVLYSDQNRLVEAEGLQQRLLKVRRKVSGDKHADTLTLENNLAWTWWRQGREEEAIHLMRKCAEARECILGRDHEDTNNSLKALLDWEEKMETEVNSEKESGSASEGSSKGGEEDTYTSSYVHVGSDDESDDGEGVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBB7</accession>
    <name>A0AAD8UBB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_757914</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aromatic compound metabolism; phenylacetate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358428.1">
        <property type="nucleotide sequence ID" value="XM_060514962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBB7"/>
    <dbReference type="GeneID" id="85398860"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000072">
        <property type="entry name" value="3-hydroxyphenylacetate 6 hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF9">
        <property type="entry name" value="P450, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1708910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="58653" checksum="50ACE3E4DAF56E48" modified="2024-05-29" version="1">MAISTAIFALKQRIFDHALQSTAISILLLPLIYVIANEFIRSKARIAKLDGPGGLPLIGNLWDIRVNAAEQYRKWAKKFGSVYQIQLGNVPVVVVNSASAARALFGQNAQALSSRPEFYTFHKVLSDTAGTTIGTSPYSDSLKRRRKGAASALNRPSVATYVPHLDVESRDFIKELYEYGKAGQAPVDPMPMIQRLSLSLALTLNWGTRMSSQKDNLFKEITHVEEEISRFRSTTGNLQDYIPLLRINPINMHSAKAREMRSRRDVYLTALNRGLDERMANGTHKPCIQANVIMDKDAKLNQAELTSISLTMLSGGLDTITTQVAWFIAMLSQRPDIQDKAAAAIREFYSEKQPLCDAEDDQQCKYIVALVRESLRYYTVLRLALPRASVRDVPYGQTVIPKGSVIFLNAWACNMDPEVWTDPEVFRPERWFEQPDAPLFTYGVGYRMCAGSLLANRELYLVYMRLLNSFKIEKHDDVDHHPVSGNADPTSLVAMPRPYKARFVPRDTSTLSNVLKATEEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCB5</accession>
    <name>A0AAD8UCB5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_744979</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358923.1">
        <property type="nucleotide sequence ID" value="XM_060513175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCB5"/>
    <dbReference type="GeneID" id="85397073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1710863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="498" mass="56651" checksum="88CB83098FC4F27E" modified="2024-05-29" version="1">MGLLHSFLTAITACAAFIVVYTVSCIFYNLFLHPLRHYPGPISMRATRWTFCHRLIKGALPMDVLELHKKYGDVVRVAPDELAYCNVNAWKDIMGHRSAGSPTFEKALKFYRPTAEQPINIVNTNGAEHAMLRRQLSHGFSERSLRDQQPLIMKYVDLMIQRLHENCSGEEPVDLMAWYNFTTFDIIGDLAFGEPFGCLEKSEYHPWVKAIFQSARLGVFAQTAGHFPFLKKILFTLLATEAAKKARGENLARAKAKLERRMDIGRKEGGRPDLIEGLLKKKDELNISFETLAANSNTLIIGGSETTATLLAGVTYYLLMNRDCLVKLTNEVRTAFKTEDEIDLVSVNKLTYMLACLDEALRVYPPVSMGLPRVTPKGGATICGKFVPENTIVAIHQWAINHNEKYFKDPYGFHPERFMGDEKFASDNREAFQPFHIGSRNCLGRNLAYVEMRLILARLIWNFDVEIDEDYTDWAKKQQVFILWDKGPLKARLTPVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCM8</accession>
    <name>A0AAD8UCM8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_635301</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1715994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360388.1">
        <property type="nucleotide sequence ID" value="XM_060509159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCM8"/>
    <dbReference type="GeneID" id="85393058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF9">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0271">Exosome</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="45"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="255"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1715994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="37772" checksum="479FFB382A8D6AD4" modified="2024-05-29" version="1">MATSKGLPRDTFAKLSPHPFLLANLQPPAPANAARSNGRAPNEARIPNVNTSSLTHANGSAVVRTGDTTVICGVRAETLLASDIPNFRTAANLDNENGKPSSELKDYDLLVPNIELATGCAPQFLPGVPPTTLAQTLSTRVYSLLHSSNLVGPEDLRIWYTRPAEKAETEGDDGDDKMDEDDDEEKSEGEKVVMAYWVLYIDIFFISFDGNPFDIAWAAILAALRDTKIPVARWDADREMVVCSRENPKPLTLHGFPIACTAGVFTGKETTDRPAAGKFWTLVDPDRLEESLCDEEVTAVVDRSEGETKVLAISKHGGTVLQPQLIREFVGVAERRWEQFYKAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD94</accession>
    <name>A0AAD8UD94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_704895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362052.1">
        <property type="nucleotide sequence ID" value="XM_060511498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD94"/>
    <dbReference type="GeneID" id="85395396"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="54681" checksum="3AD674523C1D7153" modified="2024-05-29" version="1">MHGANLSIPSLGFVDLPVEIQNHILQALASSHPASICAVLPTCKHLYKIALPLSVRTYESAAGPKNTSQYAQKRSRNLDFLRYITITKPELAQHVRRITIKHVSTSLIYRTAPSSKKPLGPESDEIGVYTNMIDASGLSDHVEDWEAVRHEWLRGLADGLVEQQIGLMFLACPKIQVLELGTPLAPRLLPRLIKAAALHGRSMKAPLLHHLREYCGEPEMPKSLFHFFNIGKEFLQLPQLRTFTCASLSSSGPNGHLFDENANPPRSSNVQNLTLLDANITQEGLGTVIRACRELKSFRWTPGDSSFLDMQIKLQDLAQALSPHRDTLEDLHIDYQGQWRNQEWYVELDGFFIGTFLREMVSLKTLHIGMEAFTGFTDLWTVPSLYNNFSPEEKELELKRAPRLINHIPHNLESLELYGCTEEILPHVRQLVDLHQIGERCASLRKLRLRFNAEMVDPSKVSLKYDEKLSRLDLEITYDRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UED9</accession>
    <name>A0AAD8UED9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_589014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359854.1">
        <property type="nucleotide sequence ID" value="XM_060506195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UED9"/>
    <dbReference type="GeneID" id="85390094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052228">
        <property type="entry name" value="Sec_Metab_Biosynth_Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534:SF3">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47534">
        <property type="entry name" value="YALI0E05731P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="357" mass="38933" checksum="6D72A2C341929989" modified="2024-05-29" version="1">MVTRAQVQNSNSHLTSQTAPQTAVFLGGTSGIGKLTLIELVSLGFPIRVYIAGRKATEPAMRPVLEDLRRKNPRAELIWVESEVSLLVETRRVCEVVKEKETNLDFLCLTAGYAPFGGRNDTAEGIDVCHSLEYYSRMLATLHLLPLLRASASASESSPGPNPSPRVLTVLAGSMLSTRIDATDLNLTRSSPSNSSSSRLFGFKTQTHMATMNTLFLDKLASDPANAGVTFVHNWPGAVDTGNMARYHTPTWWSPFPLTNLLKPLFLVMGFDEREAGERHVYLATCGRFGGKSIGGEEGNGKDKGDKNTMGEEGRNGLFLVNHKGEVSYSESALVELRGDVQGKVWDLTMEILGPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF30</accession>
    <name>A0AAD8UF30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363102.1">
        <property type="nucleotide sequence ID" value="XM_060514401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF30"/>
    <dbReference type="GeneID" id="85398299"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="37544" checksum="AF016D531736667A" modified="2024-05-29" version="1">MTLLFIDLFDEVIGNKGVLKQQEDLLALFQDSAIQLKTMVQPITDSEDDNDDGNPISGATRFTNIHERPSCFTSTSSTHQSPLGQNGGAADRLSLAKGNSGGEVDGSPADAMPAPANVGHIEALDMPHLPTTKSNPPSQAFCLQLLEATLSQACLILAGCLPVSPGDFQSIFGVTLQYRTRDEQLSQIRYLLGSDTEKRLAAGMPPWNSVRDWQGQHSLQLGFGLIADYEADVVHGKSLPPGFITALEVQRQLQNLGARKLSSNTLEVNITSAVEDPDMAARVLAPTLRAPTLQASDFGLAKALTLQLNMSLLITNLTSSAKCFMTGPAYSQLGFFKAVEASLISVTDASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF82</accession>
    <name>A0AAD8UF82_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_57970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360274.1">
        <property type="nucleotide sequence ID" value="XM_060505272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF82"/>
    <dbReference type="GeneID" id="85389171"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40135:SF1">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8814" checksum="5BE43B06D7553C19" modified="2024-05-29" version="1">MVLITRAISLTNFLVASSALGFQVFVLYPWHEQLSHDFEELKKEHIRVLDYVKGVDAGLRKGQGGAPAGQSILERLGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFA7</accession>
    <name>A0AAD8UFA7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_581461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363222.1">
        <property type="nucleotide sequence ID" value="XM_060505463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFA7"/>
    <dbReference type="GeneID" id="85389362"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore-iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000197">
        <property type="entry name" value="Siderophore iron transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF92">
        <property type="entry name" value="GLUTATHIONE EXCHANGER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="582" mass="63139" checksum="F120AD35BC0F7183" modified="2024-05-29" version="1">MSKLWSKRRPSPGRETSPLLESDLTVGAPSQADATLHSHDAPSGGVAHSDTVANQISSAERVWLFVGIFLVGYAYGLDSQVRGTYQPYATSSLNLHSSHSTINVLRSVIAVASQPTAAKVADIYGRFETIAASILFYVVGTALEASASSVEVFCLGAVLYQIGWTCIVLLLEVLVADFSSMRSRVFFSYIPAIPFVFNTWISGNVTSAVLRVTSWRWGIGMWAIILPICSIPLLTSLYTFGQRSRKADRQAESKKATVDLFHQLDAIGLAILITAFSFTLAPLTLAGGTVSHWKSPGIIIPLAFGLLCIPAFIFWERRYAQVPLIPFRLLRDRGVWSALAVRSLLNFAWSTQGNYLYTVLVVAFDFPIETATRILSFFSFFGVFSGVLMGVVIYRIRRLKGIIITGACIFTASFGLLILYPGGASSPSQSGLIAGQIIMGLAGGLFAYPTQASIQASSDREHVAVVTSLYLAIFNVGSALGNCLSGAMWTQLLYPSLESNLEFQPNKTLAALVYNSPFSTMEDYPVGGEIRDAIIDSYRGVQRLLCIAGLCICVPMVGFAFALRNPKLSEERVQPEASAESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFF2</accession>
    <name>A0AAD8UFF2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_581283</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363282.1">
        <property type="nucleotide sequence ID" value="XM_060505440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFF2"/>
    <dbReference type="GeneID" id="85389339"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="9">
        <location>
            <begin position="11"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="59378" checksum="590833FB1CD5003B" modified="2024-05-29" version="1" fragment="single">SQKAWASYFTNMIFSIGLLLEKPYSPCSDNLTHQSLYRLAVTKYLSHVFALPDRLLHIQAYLLLAMHAIYSPSTERIISIASATMRYCVMAQLHLADAEPHISPSAPSPETAATKLRIQIRRRVFWSAYTLDRAVDTTFDLPFSVPDYQITVKLYANIDDADLDAACERASFPDRYHHPRGRTGVSAALHVVYCRQIQSEILNTTLHRDFSTHFDDLPHWRLRVLDKLDRWRALCHRTHLHSRIRSRSRSFTHPEWLHMIYNYSLAMLHQPTRSTAAGPAGDWTVKSCIQACLIFRKFQRRGHHSGLNHAPIAELWLGLVAQFKCGVALLYCFFATPPALRTATYAVPEAAEAVRACSVVISILAEQWPQSICLGDAFDILAREVPLYELSSTPAKVAGIADAAAVTGPRKMRSESAGALMAMRGQLEIIVVHRNTLHMIREMALDEFPRPPSSAGTESQTQPEASLANTTAAAAAAAAQLGEGDSPSCGRTSITGDMFQPMTPHFFQSSLTSLEAEGFDLAALGFPGDFDLLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFI4</accession>
    <name>A0AAD8UFI4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_756714</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359795.1">
        <property type="nucleotide sequence ID" value="XM_060514786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFI4"/>
    <dbReference type="GeneID" id="85398684"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF8">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="615"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="615"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="715"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="732"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="746"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="766"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="926" mass="102900" checksum="CCD30D8E2C696007" modified="2024-05-29" version="1">MDIYRHGLGNMMPRNPPYHHHPPPNAPPQLYPGPSRAPPTSREDPESDGPSNRIAHTLTACCRCRQRKTRCDPTLPRCLPCERAGSVCEYYDTTKGKKINRNYVIKLQEKVRALEAELRQYTDDDSEFSHLDEDIVRPGGLVRLNDTDETPRYLGPSSGIAMTRLLVQGAKLFTDSKRISELIPEVRARRMTRMQSIVMTRDRKKSYPMISAYPAQSLPTRPIANKLVFWPTLHEKMFLGDLEAVYAGDQDPYKNLIVRMVFAISLQKMDPQYAGLADSYYLAAMEHFEQVARPKDLKSLQSLALIGQYSLLTPTRTAVYYMVGMATRVCQAEGLTDEKTIGAGNLLDPLTLDMRRRLAYIITSMEAGLAHSMGRPNGFSKADDRMDVEPFATVDDEYITADGIGQGPPSENKLVALHFFKMRMEQAEIRRVLYEKKREEPRDESHPWFAKMERDIQNWIDSSPQNPAWCRPWFTGRYHQMRIFLYRPSPQVPKPSPRAASICFEGASYIINLSKQQMEKAAVDITWVFLLNLYMSLNTLLWTVSYPEIRQAHPRDEVEELSDQTLDILERCTERWPGTAQAVQLYSIFAKACLQSYEARDTPILQASSTFTTPPSLFDGNSPQGSEVSASTAPGGGPTFKVNPPHNPPQFGFVFDATPESMNTYQWDPNFPPHPTFRSNSIWGNSSGDANPNMNPGGRRFSAYPPESPLEDSTPPATTTPGYNSSSSPPSTINNAMPTPPDSFNSGPVGTPSSSTISPPPMGTPAMSQSSPLVLQHGTPTMVQHSTNMSPPPPPVPGSRGPGGFGAPPTSNPGAPQRPLPNYNPTTDWFNPPPPFINPDAFSSMSNSFFGDSLQVNGFNSQNPGLGLDQFGGPFNWSQERQGSLSQQQQVELLNVLENEGMSDIDAILNMGMNNPSPAASVWPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFK5</accession>
    <name>A0AAD8UFK5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_583652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362173.1">
        <property type="nucleotide sequence ID" value="XM_060505682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFK5"/>
    <dbReference type="GeneID" id="85389581"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="14"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18204" checksum="9199F54915D9ACE5" modified="2024-05-29" version="1">MPPKPAQFGRIGLVIPLFYRVFFLGIEPISALVGAYYAHIQPDDYLQLTHAVSKPEIIPQGTSIVLSQLANLYLLFALNEALVLRATSDLRVWKTVLFVLLVADFGHLYTVRSLGPEVYYNFTKWNAIDWGNVPFVYFGASMRIAFLAGVGLSGRPASVRKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG74</accession>
    <name>A0AAD8UG74_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_393207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363361.1">
        <property type="nucleotide sequence ID" value="XM_060502803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG74"/>
    <dbReference type="GeneID" id="85386702"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="786" mass="86887" checksum="7EFD70D982137AB9" modified="2024-05-29" version="1">MADTPAGTTASTDTGIRDDAPVATSAPTPSSNISQPSPSSLPSTITDRRKRSLPEGSPEGPEEGRSTPAAAAAAATTAANRRRSHKVSRACDFCKSKKLKCSGTIPCDVCTRKRLSCIYDATYRRGRPPTPPPASSSGPELFEARLVPSTSLEVHRRPLPSAAPLPSPAPREPPLARQSAARSRSRDHVAEEVEAAEGSRRSVLPGSRASAEVEIAEIEGQYVDTTSSLTFLHRAWKRLSSQRSNITDVPGNVPSGAEQHQRLTRAGDKPFDSQPLDVSTLPDRLTGLDMLDFYFDVCVVTYRCLHQGYVAQWFEVLLANAKDGRPLHHEIGHARASIVLTILAIVTLRQSKVRNVDEEKFSRLLRSDALFSQALSLTDAEIGLPKLESSQARLLQVLYLLQTSRMNQAWYVFGSILPIISALGLHRKSGRLRASSDKDYILSQCRKRTFWVAYTIDKYLSVVFGRPRMYRDDDIDQDFPDCVNDEDMTPQGRSSDEPEMDCHVESLIFHAKLAQIIDGISREVYSIKPVHKDDRLMIAHRYGKALHRWRESLPHHLGTVRPMSLIPTFRRQNTALKLAYCHAIMHANRPFLLGTGGSRGGQRSPLEDSIDECITAAKAALETVDGMASDGTLFHAFWWTPYVTFCALAVVYVYEIQRGRQDPEMGLFELADRCQNHLAKATTAESPSRRYSVILEELRQEASSHSEGPSGREKKPTIERAEHGGAEPMQLDEGSGAPAPPADMGEVFQQHGFEGMTNLLSGWETTDWLDLDSSVHDLLQSFQLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGX1</accession>
    <name>A0AAD8UGX1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_585452</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361398.1">
        <property type="nucleotide sequence ID" value="XM_060505849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGX1"/>
    <dbReference type="GeneID" id="85389748"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000075">
        <property type="entry name" value="Nicotinamide adenine dinucleotide transporter 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF1">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06780)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="75"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="181"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="309"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1719314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="442" mass="48479" checksum="3EE52D14091C5693" modified="2024-05-29" version="1">MSHDEQPDAERSAPHHNDEEYGPYPTSTYPNYSSSRAYPATAPARAAIAAIEEAVAVMPDNETITAFERWAAGASDAQFNALSGAVGGFTSGVVTCPLDVIKTKLQAQGGFNPVEKGRHVGHGPKLYNGLLGTARVIWKDEGIRGMYRGLGPIVLGYLPTWAVWFTVYNKSKDWLKHRHDNTVLINFWSSIIAGASSTVVTNPIWVIKTRLMSQSVAHDPGKYHSQFPRSGNTPTSRPTNHSSWHYRSTIDAARKMYTSEGVLSFYSGLTPALLGLTHVAVQFPAYEYLKTRFTGQGMGEPTQGDSQESQWMGVLGASILSKIMASSATYPHEVIRTRLQTQRKPVGGAEYLQGLGIKVPLSEDGKPQQPLSPKYRGVVSTFRTILKEEGWRAFYAGMGTNMMRAVPAATVTMLTYEFAMKHLNHARSEGKRKLGRGTPAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH36</accession>
    <name>A0AAD8UH36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_631549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361635.1">
        <property type="nucleotide sequence ID" value="XM_060508910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH36"/>
    <dbReference type="GeneID" id="85392809"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="27"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="3">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1720124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="621" mass="69263" checksum="B6F1F4BB9F1EE5A4" modified="2024-05-29" version="1">MRLIKASSIHSNNLQLVDFNPDQLPRYAILSHTWGDNEVIYVDIRNENAATKPAFQKVRYSCIQTLADGLEYVWIDSCCIDKSSSAELSEAINSMYEWYMKSEVCYTYLSGVPATVDPVKTDGAFASCRWFTRGWTLQELLAPAEMVFFSEDWVKVGEKTTLSKPLSVITGIDEDILTGLRPLESASLAKRMSWAAHRQTTRPEDVAYCLMGLFGVNMPMLYGEGDRAFLRLQEEIMKQSDDQSLFAWVDLSASTETYHGLLAKSPVNFAYSNSIMPYQDWEPRPPYFMSNRGLRIDLPLTLRDQDIFVAALDCPAPPDYEDSTFLAIYLRKISSGGDQQFARVQVNQFAKVQERGNKQTLYVRQTFNGVADAEGVFPQHIVQLRRGPPRDQYSVLNLVHSKEADRGDRPAACTSSRGSGRDLIHTATGKTIAFRIPKAAGQLAGAITFARTDGSRLLVMFGSTDGIRAGFHARELPPRFPGMSQNQNQAKTKSSSNAKENQQQEPPEVTFSFDDLQQMFRPTPAGVDVELERFRVRVDVETVIANASKYLMADVLIEPVNRPWDPFEPLDAALGWYEGATGRQNRGQAAAAQAATAQVAATNSTSGKTKRASSGWRRLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH37</accession>
    <name>A0AAD8UH37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_579135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364227.1">
        <property type="nucleotide sequence ID" value="XM_060505205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH37"/>
    <dbReference type="GeneID" id="85389104"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="58552" checksum="11D6CC4DE6AA9F84" modified="2024-05-29" version="1">MVVRSSPGKTASNTLLAIRRYLSNARLEGRETKFSNSTSLDTGFDNAILFKYEQEVEAGANVTASAGIEIVCTKCYIKGKASAHLTIDGTFNATKVATEIGNEFEETFDNITTYAKNYVSGVMDNLSDGLDADDFDFPPLNITFDLDLDTTLSAGLSYTLNLYTSTTPLGSKIGDDLLLGVVFSIDLILSVESELQMSSGFHLRMDDEVGFDIALFSKNVSSVNFKGGQFEFLPVIIETAGVELKAILRAGFSAGIEISSPVDSKEIELFNNTIKVPGASAGIEVSVFANIAELSTGVTALSTPDEDGCVLRAVNAYQFALGAAAGASVQIGDRIWGPVPNTQIPLFYTTLGDACASTRVPTTTATKELTTTTLSKKVTYTGIECLTTGLINCPPQLQTLRKFVATETFITAVASGVEAVFPVATKAVVQDVVSFGSNAQPLISSSGVPKEFTPSPSASATSTNPPGVLDGEVDGVDKKIIVGVSIGAGVILMAVVVGACMFWQRKRRYSPVSRTNGEVTYTQDFRPSEFHDPIKNQKQTQVNIVDVHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHC7</accession>
    <name>A0AAD8UHC7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_578851</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364362.1">
        <property type="nucleotide sequence ID" value="XM_060505172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHC7"/>
    <dbReference type="GeneID" id="85389071"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF19">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="540"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="498"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="74110" checksum="FAE426E32C5FAD30" modified="2024-05-29" version="1">MLLTRPTASQSIQQHQQQQQFHQHHSDLYHQYQTQPQHFYPHSIDFDVEASFDDTAPGLTSSSISSSPLSTQSFLPSHYSLASNSASLASYDTSHLAVPRRSATNTSGFEDSALNYDHHHNLMQSDAWVLGNQYAPKTVGRLPHQRESSLSSLGSAGPASPFSHSTSNPQIAVIDSTPDGLYDMQAHDGNAYYQLTNKSMAVSHDNMYPNYNGLQNISSDMAGYASALNVQRPRSDRGLLPAPELSMAGSRSHPNSVASSIAGDSPATPSHLEQEDDRRRKAVFSNIPKLDRTMTDIYNDELYSPNFTITSAAPPQNQMAVSPSNDVFAQRLSAANNQHLSAAQSPVSSVSRDRSPFRQGSPLAPMPSHDFGGGGQASRLRFNSAHQIREQKKAEQDAQIMRQQMTVKSEPETPKTISPKDAMLEFHDGDAEPSFSLFPSQETVDIEDIAKAVATQDQQVNFARSAMQNGATFPYMPAQLQTAVHIPQQYPFIAHPRQSHEQIPRLSSAESSTGGSDATSISNATPIAKPAGAAADGGTYTCTYHGCTMRFETPALLQKHKREGHRQTQGIGGPRRPEAVVTSPDSMLNSQAGPHRCDRINPSTGKPCHTIFSRPYDLTRHEDTIHNARKQKVRCNLCTEEKTFSRADALTRHYRVCHPDVEFPGKHRRRGHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHE3</accession>
    <name>A0AAD8UHE3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SPFH domain/Band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_584696</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361785.1">
        <property type="nucleotide sequence ID" value="XM_060505783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHE3"/>
    <dbReference type="GeneID" id="85389682"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF31">
        <property type="entry name" value="FLOTILLIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="27"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="536" mass="59608" checksum="38E2F7565C183EAE" modified="2024-05-29" version="1">MSYRVAAPDEYLAITGMSVKTVKITKAAWVWPFQRCMRFRITPHDYAMSLQAMTKEKLQFLLPVVFTVGPDVNQRGANAAHQSSHHSETPDQQQHDEDDSYISSNRREDRGDALMKYAMLLAESADKKTSSLVHLENIVKGIIEGEVRVLVSSMTMEEIFTEREVFKRRIFRNIQSELSQFGLKIYNANVKELKDAPNSNYFESLSRKAHEGASNQARIDVAEAQLRGNVGESKRKGEQEREIAKINAETAVQKTDRDIERATAEANLDTRQASLSKDVEIARVEARRALESKDEDLKREVEVKRAAAEIERLRATEVVKATIEREARQQKADAEAYAIEADAKANFEKSQRETEAKAFKTQKDADAHTSAEFNRTTKTADANAYKARQDAEAHQYSAQLNAEADLAIMLKKAEGMAAMADAYGKMSTAFGGPAGLLQYLMIEKGTYVQLAKANAEAIRGLQPKISVWNTGSQGSGEGGGNSGIDTMRNVYQMLPPLMTTINEQTGITLPEWQFGKMNAGMQAMQSENGSKINGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHF8</accession>
    <name>A0AAD8UHF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_795211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361384.1">
        <property type="nucleotide sequence ID" value="XM_060515833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHF8"/>
    <dbReference type="GeneID" id="85399731"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="25767" checksum="62AEEE1E9CB477E7" modified="2024-05-29" version="1">MIVTELGAVGVKPGLDIMDESTPEGRIYMSVYRKIIVAPGAPHRLFLGVEIEDPSMSWGFFDWDSIEHHEKFAKEHGAELCKDLHKVLTYGEFCKHITATPSLPDALKSVVTDVFIIYFPSDITPEAKDTATTRLQEILEEGFGQVPEVTATSYGWGVQDNFPVKGGDPNQTGSILTAFVGWFNVEANNTFHQSESYKEIERKLENMEGLIKLRPFRLRCTVLEREAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJD7</accession>
    <name>A0AAD8UJD7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_732297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362894.1">
        <property type="nucleotide sequence ID" value="XM_060512892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJD7"/>
    <dbReference type="GeneID" id="85396790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="21500" checksum="3201F23F14117FD3" modified="2024-05-29" version="1">MSGDPELPRRQHLEIHHRMRPRHNVFQPPQRRRPGIRKPTGLESTPYDHNLGPMCVGKQSAIDAFVCPARTHGTIRYKATTSGWQSLRREAYKPHVFDAFTCKSSAVANLPCCRADALNHESESIRGFYVCGLCWELFKRKQIVSSSFSSSSNDRSQQGLQAANVPDGKLLPEHDHDNSNMLKITELRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJT2</accession>
    <name>A0AAD8UJT2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_651594</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365266.1">
        <property type="nucleotide sequence ID" value="XM_060510462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJT2"/>
    <dbReference type="GeneID" id="85394361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF9">
        <property type="entry name" value="DICARBOXYLIC AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="60"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="580" mass="63941" checksum="1359CE493C966686" modified="2024-05-29" version="1">MSDGLVKRASSSEGAHGGHDIEKTGYQTQTYDDNLKENVHIRGLETSEDTKLHRGLKARHITMIAIGGAIGTGLIVGTGKALAQAGPGSVFISYTLVGFIVFLVMAGLGEMAAWLPISSGFTGYASRFCDPSLGFALGWTYWFKYIIVTPNQLTAAALVIQFWVDREKVNPGVFIAIFLVAIVCINYFGIRFFGEFEFWLSSFKVVTIVGIIIFSLVLALGGGPDHDRKGFRYWKNPGAFKEYIDTGDAGRFYGFWSCMVNATFAYLGTELVGVTVAEAQNPRKTIPRAIKLTFYRILFFYCFSVLLIGMLVPYNSPDLAFANKSQTGASASPFVVAATLAGVKVIPHIINACICIFVFSASNSDLYIASRTLYGLASDGSAPAIFKRTDKRGVPIYALGFSAMFALLAFMNVSNDSKAVFGYFVNLTTIFGLLTWISILVTHIWWCRARKAQNIPDEILPYVAPVGIWGSYGALFLCVIIALTKNYDVFTGGDFGKEKYKTFITGYLGIPLYLILIFGHKLYYKTRGVKPHEADFYTGKDIIDREEEEFLARKAAEKEANGGKGGKGGWFYKTFLSWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK14</accession>
    <name>A0AAD8UK14_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_793984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363003.1">
        <property type="nucleotide sequence ID" value="XM_060515794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK14"/>
    <dbReference type="GeneID" id="85399692"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042173367" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="380" mass="41493" checksum="E675EE996DB4A341" modified="2024-05-29" version="1">MRILNLFAVLSLYGATALASEGDELSEVQAQAIEALQAAEGNGTFGKRDSCTLFNARVRRDWNSLSGSEKKAYTSAVNCLLTKPSKLTDFAPGARNRYDDFVAVHINQTLSIHGTGNFLTWHRYFTWAYENALRQECGYNGYQPYWNWLSYREDPSKSPMFDGSETSMSGNGAYKYHNGSTSGGGVYIPSGEGGGCVTSGPFANMTVHLGPVSPGIDGLAVNPGGPLAYNPRCLSRDISAWTSQHWMTPENVLNLTVGAAAENVLTFQNELQGRFGDGFLGTHTSGHFIVNGEASDLFSSTNDPTFFLHHAMVDRVYWLWQALHLGEAFNIAGTITILNTPPSRDARLDDLVIQEPNASNRPISDLLNTLGGSPFCYIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK26</accession>
    <name>A0AAD8UK26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_618462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365847.1">
        <property type="nucleotide sequence ID" value="XM_060508076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK26"/>
    <dbReference type="GeneID" id="85391975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="128" mass="14131" checksum="AAAF554DECA6C37D" modified="2024-05-29" version="1">MSADILTAALPTFFMLFWTVLICHFSASVSVKFVGGMHHADKRWGVGGHMGRYRHRLSADVLLFCRSVQPVLTSWKGKERQGNGKFDSIRSSPVSVPTVSFPAPVNQCQTAVGNNSDSCLHYLTLHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL33</accession>
    <name>A0AAD8UL33_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_624617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363975.1">
        <property type="nucleotide sequence ID" value="XM_060508455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL33"/>
    <dbReference type="GeneID" id="85392354"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="53" mass="6051" checksum="3F6A22DBD2B3A297" modified="2024-05-29" version="1" fragment="single">MAPEVDVKGWISLSSGHLLRRHRVLNHCSLPEPPLSVHQHYLPPQEIDTQSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UME4</accession>
    <name>A0AAD8UME4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_751282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366103.1">
        <property type="nucleotide sequence ID" value="XM_060514031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UME4"/>
    <dbReference type="GeneID" id="85397929"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="26534" checksum="94DF2B4C1981973B" modified="2024-05-29" version="1">MSRESADPTVALVTGANQGIGYEIAKRLASEHPDYHVFMTGRRKEAIEKAASELQEAGLNVEPLVLDITSDDSIKSAIDTVRTKFGHLDVLINNAGILLGKPEDSIRQKLATVYNTNVFGSIAVTDAFVPLLRESSKVKRVVFVSSGLGSLAIRTDPSLGPVRDFIEYGSSKAALNHAAMTFASRYRDDKMWKFNICCPGYCATNMNSYEGPDEASLGSVQAVHLATLGPDGASATFSNRHGPIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UME5</accession>
    <name>A0AAD8UME5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363799.1">
        <property type="nucleotide sequence ID" value="XM_060514332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UME5"/>
    <dbReference type="GeneID" id="85398230"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="33773" checksum="DD034D7B6F8CF54D" modified="2024-05-29" version="1">MSRGHRMSKRASKRRQASPEPDLSLTEGFPIVKTRRYPSRKDIEYHATPRHRSLYEHHHHPPPPRSPKRHRQNRQAEAKSDTDGDLKMIPMPPESPSTALVLRTSRTPGYKKDHRKNDNDGYLDIVRRRRKPKHKPDLELNLEPVNHRASKRRRSINDTGREIRQHMQQQNSDLVVDNYHFRNHILSLLDEQRSSVESWARSVGAGGPAEPMDWQPEQERVVYIARDLVEYGCYEDRWRIGGGQEEQPQQQLEDRPTAQLSSGLVSWADQTEDGSEMCGAPVLGLSLVDVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW3</accession>
    <name>A0AAD8UMW3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_695253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367317.1">
        <property type="nucleotide sequence ID" value="XM_060511354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW3"/>
    <dbReference type="GeneID" id="85395252"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="60"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="339" mass="38205" checksum="B3C3DCB294C01CB7" modified="2024-05-29" version="1">MDIDQAPTTETVSSPPPLLQDEEAHLKARTSDSKFWLDFSLFDDGLNAPRAASLAALSEFHRFPDLPPEIRLKIWSYLIAPRVVTACCFERDARLPVRREAFANRSLAAPYDPLSFSYSSSSSYSPTNTASESSKRVFNPTCPLILLISRESRALGLKHYELAFGWRISALLSDTPIARPPRVWFNFALDALYLVGELEAYDQYGFNSPMVYFLRKEDTRRVRHVACAFEELHYPEQESDQIFGCLWHVVDRFAGAKRLMVAVTPRDEEGMKGCLMLNPDNIMQKIWNGWILGTTVTSSSLADTQILMVREGDLADVLACHAEEDEEKGGKRSVVTVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW7</accession>
    <name>A0AAD8UMW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I glutamine amidotransferase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_578994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364296.1">
        <property type="nucleotide sequence ID" value="XM_060505189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW7"/>
    <dbReference type="GeneID" id="85389088"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF7">
        <property type="entry name" value="DJ-1_PFPI DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="58"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="234" mass="26365" checksum="B17EEDBEAC54E913" modified="2024-05-29" version="1">MDFNLSKPNRKIHAGVILTKGVTEMLDVAPFEFFAWTDKTSRQMLNLPQEMWEDDIEFDLHWITEDGKPAHMKSRAQIQPTDSFESCPPLDISLMGAHDLKYKTSEAELVFIRKVYQQCSAFLTICGGMFPLLEAGLLTGKTATCPRMIVGAMKKSVPVVNWVETRWAHDGKLWTSSSLLNGTDMMRAFAEATWGGKANNGWVEAALDIGGYPVRDVDFKDFEGHHYAVEQLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNA9</accession>
    <name>A0AAD8UNA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FMN-dependent dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_626091</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363545.1">
        <property type="nucleotide sequence ID" value="XM_060508538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNA9"/>
    <dbReference type="GeneID" id="85392437"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000132">
        <property type="entry name" value="FMN dependent dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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    </dbReference>
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        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF75">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_4G07050)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="111"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
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        <location>
            <position position="208"/>
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        <ligand>
            <name>FMN</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
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            <position position="323"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
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        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
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        <location>
            <begin position="354"/>
            <end position="358"/>
        </location>
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            <name>FMN</name>
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        <location>
            <begin position="377"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="439" mass="48554" checksum="F73C57D8BDEE456B" modified="2024-05-29" version="1">MSDPNSPHIKSRDTPSWGLYQRENFWKLNEGEVPQFNTHPDKLEELAKQKLTQNGWYYASSNAGLSHTHLANRQAFFRHKIVPRQLVDTNERSTRTTIFGHEVSAPFGIAPIGINKIYHPQGELPVAKVAGELGIPYSLSTAGSCPIEDVARANDAGRASAIRAQSADKSKIPEGPRFFQLYMPHDDELTLSLLTRAHESGFTACILTTDTWQLGWRHDDIATSNYAFYRGIGADLGLTDPVFRKRLAAKGIDSQKEPEKAAAMWIDSIWHGRAWSWDKAVWAREQWQKISGGKPFLIKGIQRVDDAEKAADLGFEGIVVSNHAGRQVDGAIASLDALENIAEKVGDRTVVTFDSGIRGAADVVKALALGAKFVFIGRLWIWGLSIMGEHGVRHVLRGLLADLDILMNVAGIQKVEDIDKNLLESLPKSYGLISEKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNH7</accession>
    <name>A0AAD8UNH7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_770508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_060515345.1"/>
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    <dbReference type="GeneID" id="85399243"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042224323" evidence="1">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="100" mass="10735" checksum="46C8176BCC3ED969" modified="2024-05-29" version="1">MKQFTIVTLGLLSTAFALPPQQDAQHPGLVPRAAICKNFYLSKKDGSGNGPWTCCCANTQCTVSWGVTSTAKLNANLGGDWSPVDDKYHMYVAAGSRCDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
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    <name>A0AAD8UNI5_GLOAC</name>
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        <submittedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_717542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
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                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367722.1">
        <property type="nucleotide sequence ID" value="XM_060511958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNI5"/>
    <dbReference type="GeneID" id="85395856"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08366">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016901">
        <property type="entry name" value="APC10/Doc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DOC" evidence="7">
        <location>
            <begin position="126"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="340" mass="38008" checksum="48A608317DDB27BC" modified="2024-05-29" version="1">MDDRRRGNIHGGRPRSDLRSPEQLTQNGFDLDAEPRSQWSGDYYDRRATRALGPNGGSHQDEEDSDDGEAFPPQRVDWEAMRAGANMEEYIRSQPIPEYSDEEGISMPLDDLGEISGTDTSVEDGENGDQVGDQQDEPEFDPLAVGLKEISNLGKFTVSSHKQGNGVDQLRDDSLKTYWQSDGPQPHKLTVYFIKRVGIRDIRFYVDYNEDESYTPTKIIFKSGTSENNLIQFATMELSTPSGWQIVPVDGAGGGPDGNTLVSYVFQMQILENHQNGKDTHLRSIKIYAADTDTPSIDADMSNRRAVSEEPDEEPVDPWDLAVLEAGLSVPDFMKEPEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNL5</accession>
    <name>A0AAD8UNL5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_719946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364429.1">
        <property type="nucleotide sequence ID" value="XM_060512231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNL5"/>
    <dbReference type="GeneID" id="85396129"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="450" mass="50457" checksum="F497E0032CBB8F4A" modified="2024-05-29" version="1">MREVEIFPQTFEIINDASLFSIKVTSEVDFQVILPDVVPKRFKKIQSKSEVTKNNEVFTKATQDFFNILTTWPSGDGAGIKLTISAASPSDVTIQGMMESGELESDRQFPVYETHWRTHALSIDRKLLAGGQLPKVACVSEVSFEAIHGRPFSPDAFSVVTSALISVRTMLWEFLPPQVRMTYDRRLAWQSDLKAFRNALGAALTDTPFLKLVEFEIVTDSGDPSNELFQPPDMTGDGGDALSVGVRRLLQLETLEKLHLGSRWILTSAAFDAQLNCPRLKDLHIDLCVTAVDGKWLYTGDFDNLPVNEGYYEFDSGDSDASGFYPVVRTREAEGDIPELAFRVTPDNPVFVPLISTIAKAVPGMPSLRRMRVMLGGSVRGTIAPLDIRYLAPGEVETDESIENFSKKNLERPRWCLMGYRDFDKSWRVPQEPKNYDEGALKRDIDNDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNV2</accession>
    <name>A0AAD8UNV2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_574902</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366257.1">
        <property type="nucleotide sequence ID" value="XM_060504751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNV2"/>
    <dbReference type="GeneID" id="85388650"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090422">
        <property type="term" value="F:thiamine pyrophosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000011">
        <property type="entry name" value="Mitochondrial thiamine pyrophosphate carrier 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 13" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="121"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="214"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1726202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="34994" checksum="6B75C0BE75983669" modified="2024-05-29" version="1">MSPSGERLKDEGSRLQVVTAGATAGLFARFVIAPLDVVKIRLQLQTHSLSDPLSIRSARGGPVYKGTLNTMRHIIANEGITGLWKGNVPAEMMYVCYSAVQFTTYRTTAQFLKTAFDNRLPNAAESFIAGAAAGAAATTATYPLDLLRTRFAAQGNDRVYTSLRRAVADIYRDEGPRGFFRGLGPGVAQIVPYMGIFFALYEGLRLPLGDLHLPWGGGDATAGVVASVLSKTAVFPLDLVRKRIQVQGPTRARYVHKNIPEYPGAVRAMRIIFAKEGVRGLYRGLMVSLIKAAPGSAITVWTYERVLRALQRLDGSDDQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP51</accession>
    <name>A0AAD8UP51_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_576631</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365429.1">
        <property type="nucleotide sequence ID" value="XM_060504934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP51"/>
    <dbReference type="GeneID" id="85388833"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="581"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="625"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="656"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="834"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="875"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="166"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="106"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="907" mass="102072" checksum="A7D5AFAD0774B958" modified="2024-05-29" version="1">MDPRYHRTPSPGQPAQHGYQLEDNPFNNQAQQGYHQPPPQHVDDPYGRPSPHSQLDIPMAPGRYGTPSDQLQLNAAHSVSNLSGYDTPVNHGDYGVNPEAHHDAYYNQSYEPSPHDPAHPYDQPTGYNEYDDNRPMLPHQDTMTTDGGYQDNPTPQPAGGGIKRWKTVKQVLLYRGNLVLDCPVPPRLLNQLPHGERDEFTHMRYSAATCDPNFFYDDNFTLRQRLFSKPRHTELFIVVTMYNEDEILFARTMIGVLKNVEYMCSRKESKTWGKDAWKKIVVCVVSDGRGKINPRTRALLAGMGVYQEGIAKQQVNGKDVTAHIYEYTSQVGMTIKNDVVTLVPKQQPVQMLFCLKEKNSKKINSHRWFFQAFGRVLDPNICVLIDAGTKPGGNSIYHLWKAFDLEPMCAGACGEIKAMLGTGGKHLLNPLVATQNFEYKMSNILDKPLESAFGFISVLPGAFSAYRYVALQNDKNGQGPLEKYFAGEKLEGAGAGIFTSNMYLAEDRILCFELVTKRNCHWILQYVKSATGETDVPDTVTELVLQRRRWLNGSFFAAIYAIAHFYEFFRSDHSILRKLMFFIEFVFNTINMIFAWFAIGNFFLVFKILTTSLGEDNLLGRTGEILGVVFTWLYGISLMTCFVLSMGNRPAGSGAYYITMVYFWALIMIYLLFAAVFIAVKAIIADVNDSNGFNVSDLFKNPVFYTLIISVMSTYGIWLIASLLMFDPWHMITSFAQYMLLTPTYTNILNVYAFCNTHDISWGTKGDDGAEKLPTVSTKDGSGKTDLPDEADLNAQYERELKVFSAKFVQEVKAPTDSQKAEAQMDYYRGVRSVVVLAWMISNFGLAAVVLSAAGLERISPTASSTDDTDGRANIYMSVVLWSVAGLSSFKFIGAMWFLVVRMFRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP52</accession>
    <name>A0AAD8UP52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_622092</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364699.1">
        <property type="nucleotide sequence ID" value="XM_060508308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP52"/>
    <dbReference type="GeneID" id="85392207"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF6">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="54895" checksum="0E7A6692E1274C73" modified="2024-05-29" version="1">MFYQLKWFDPTLPDSVISSQAGILHASFTAAQFITAMIWGRLADSKRFGRKTVLMIGLLGTCFSCIGFGFSQSFAQALFFRCLGGATNGNVGVLRTMISEIVREKKFQARAFILLPMTFNIGVIIGPILGGILSDPAGSYPSLFGDVAFFRKYPYATPNLLSAIFLSCAALSVWLCLEETHDALREEGPDLGSRVGASIASLVRRIVARQRRGLNSNADAAYTPLHSSSASTTDVDVELSPESAPAKQKPRPRYRHRLPFRRIFTRNVLMTFSAHFFLAFHVGTFNALWFVFLSTPTSASPPHLPFRFSGGLGMPPQSVGMAMAILGVIGISLQLLVYPRLSAHLGTVKAWRLFLYFFPVTYFLVPYLAVVPTTDAAPPPGPKGGPAIWFAIVGVLLFQVLGRTFALPGQTILINNCTPHPSVLGTIHGLGQSVSSAARTIGPVLCGWLYGRGLEGGVVGAVWWGLAGVAVLGVMASWAVWEGDGHEIWIDGDEVAAEEEEEVHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPE8</accession>
    <name>A0AAD8UPE8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_749447</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368217.1">
        <property type="nucleotide sequence ID" value="XM_060513765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPE8"/>
    <dbReference type="GeneID" id="85397663"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000003">
        <property type="entry name" value="Long-chain-fatty-acid--CoA ligase FadD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF6">
        <property type="entry name" value="ACYL COA SYNTHETASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="43"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="469"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="575" mass="63072" checksum="E3B340761E514F90" modified="2024-05-29" version="1">MAAEASTAPVSEPLAPEQKLSILHGPRDPPLVDLSLGELLELQTYQHGTKECLVIPWTGARWTYNELNQQSLLLAQALLEMGIKAGDRVGVMAGNCEQYAAIFFAVSRIGAILVILNNTYTPSEAMYAVEFSECKILFTTKQIGRLDNTKFLSQIANKINGPKIIMIRGDTSGYQTYDDLIKSSSRQSPRELHLAMSKVVPHQVCNLQFTSGTTGRPKAAMLTHHNVVNNARFIGDRMRLTPDDVLCCPPPLFHCFGLVLGLLSVITHGAKIVYPAEVFDTKATLKAILEEDCTALHGVPAMFDSLFQAAPDDFKSSKIRTGIVAGAPVPRYLMELMVNRLGMREFTSSYGLTEASPTCFNAFTDDALGKRLTTVGTLMPHASAKIVDRDGNVVPMGQRGELCMAGYQLQAGYWNNSEKTNEVMVRDSAGVLWLHTGDEAVFDDAGYCSITGRFKDIIIRGGENIYPLEIEERLMAHPSISQAIVVGLKDEHYGEVVGAFVQRAENADKPSFQELKDWVRQRLGGHKSPAHIFWLGEDGVPANVPLTGSGKVRKFEIAKVGDEILKKSRTVSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPL2</accession>
    <name>A0AAD8UPL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_363935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364190.1">
        <property type="nucleotide sequence ID" value="XM_060502596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPL2"/>
    <dbReference type="GeneID" id="85386495"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF9">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="59012" checksum="28B86C112D65AE24" modified="2024-05-29" version="1">MSGMEGVSDFAQQSLKDLGVDSDAVHSRSITASIGDDVVLNPVGLTSPIIQADDDEDLDDNGDDDDSEANIIALKLLRHFRQGPGQWMDLFDTSAHFSCKIPIRAMTRPLLKSAICALAAKHLSRTQSNHSQTRQTRSTRASMAPSATTPPDWQYHAVRHYHQAIRRLKHAITLAGARDDARHSETSDQHADTFAAVAILCMYELMNAPGNAWKAHLTALSLYSASDSALGGCSPVSIPQSPTKGPIFWSLARQDFLCAFISETQTRLNLDHIRLWQNFGLATDERNLVLPFSPFSTADIRSSTNVDEDSKSNELLWLLGKIVNYITNGDGIRPEDYSKPAGQRMSLGLMQELLLGRWTKLEVELQEWYESLPPTFVPSARTRFFSRQGELGDDETDMDMERVWYDIPMCASTMQSYHMARILLLVNRPQESTAIRSTVSARLRSYRLIQKEVLRHCKEICGISLADPTDAVRVHSVQPLFVAGQAFYTRPEQDLVLELLSGIETELGWATNHQRRKLIDEWKVNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ34</accession>
    <name>A0AAD8UQ34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_614767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366857.1">
        <property type="nucleotide sequence ID" value="XM_060507864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ34"/>
    <dbReference type="GeneID" id="85391763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154347" evidence="3">
        <location>
            <begin position="23"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="27828" checksum="6B00A5F01A15A133" modified="2024-05-29" version="1">MHLSLLRWRLLAAVAFVTAVAGQTCYWPNGVEAKQAVACPVAGGTEVAACCFQNHYCMSNGLCFSQTELSFYRGACTDQNWSRSGCPKYCDKEEITGGVPGRHCGVALCGDNKFACQNSGNCANYTFGVPAGQMLLNEYLKSDLGDLATTTVTATAAAGGQSTGTAATCSATAAESSISNGISTGAAAGIGVGIGAPLALAIAALTVMLFREKRKTRAALSSQIDSSGTGPSSPWAKSERTAYVPVEMHGQPVPNELSSNHDRRHELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URE1</accession>
    <name>A0AAD8URE1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase family 3 N terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_608592</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368656.1">
        <property type="nucleotide sequence ID" value="XM_060507486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URE1"/>
    <dbReference type="GeneID" id="85391385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000008">
        <property type="entry name" value="Beta-N-acetylglucosaminidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000013">
        <property type="entry name" value="Glycoside hydrolase family 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050226">
        <property type="entry name" value="NagZ_Beta-hexosaminidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480">
        <property type="entry name" value="BETA-HEXOSAMINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30480:SF8">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="6">
        <location>
            <begin position="116"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1038" mass="113505" checksum="B33461783A9F2E99" modified="2024-05-29" version="1">MIIGRGWCSSPPLPPHMASHSQPASSSSFSYFVPRDGSGSHPSSNRESTSTSKSTSTSENGRRHHHHNNTRQRQHHLPPFKPRHLERYYARQNVTSRRPLAMGQVKELDPLWQDLDWAIGQMLIMGWDGTEVTPQIRSLIEDHHLGTIILTAKNLKSAQETAKLVKELQTIAHKAGHPKPLLIALDQENGGVNSLFDEDYVCQFPSAMGIAATGRVELAYEVSKATATEVGACGINFMLGPVLDVLSNARYQPIGVRATGDDPQEVSQYGIAAINGIRDAGLASCGKHFPSYGNLDFLGSSLDVPIITQTLEELSLSALVPFRNAIATGKLDAMFVGGCGISNPSMNVSHACLSNQVVDDLLREELGFDGVAISECLEMESLTHELGVQNGVVMAVEAGCDLVLLCRAYDVQLEAIKGLKLGVENGIFTKERIYTSLNRVLRLKDTCTSWQTALNPPGISLLSKLHPSHMALARKSYDDSITVIRDKEKLLPLSESMHQEEELLLLTPLVKPLPASSLTKSILQAKDAQRLAPTPHDTWLHREKGAIMSGEGVFREFGRSLARSRHGKLLHTSYTANGVRPVHENLIHRASCIIIITADANRNLYQAGFTKHVEMMCSMLRTRGQKKSVIVVAVSSPYDFAMDKSIGTYICTFDFTETAMHALVRALCGHIVPKGTLPGTLRKSKKVLKSRQHWIVEEYDRRRDAHGLEELAKAVARANTVDLGHLESMPAACFELSKPNVEEAHFVVRNSSTHALYGFAATYFVDGIGILGAIFVDPTKRNVSVGRSLHRRALRHLLTNNTNNNKQRVVKKIQLGTSFPGVFLGIPIDEGGGVKSWFANNGWDVQFPKRLTNLAIHDLSGWAIPEGLLQSIQRANLSFDLIHGLDNAESVLGHVAANANPEVLELYRSALQETKACGIVRAKGAGDALLGTIIICRPGSPLATYIPPLLSAVDEGIGGVLAPVIHPGPQDTLVLQGLTLMGVRQNKAHKSAKTVLSWVSFYHTPHHLILSCACWDFTDDLMCAGARRRLRTCHGDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URL2</accession>
    <name>A0AAD8URL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366659.1">
        <property type="nucleotide sequence ID" value="XM_060504687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URL2"/>
    <dbReference type="GeneID" id="85388586"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF2">
        <property type="entry name" value="CELLULOSE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="213" mass="23543" checksum="333F944AE24CED4A" modified="2024-05-29" version="1">MWSASAEDKVKVMPLGDSITGSPGCWRALLWKKLQDNNMKNIDFVGTLPPQGCGFDYDGDNEGHGGLLATDLARENRLERWLGDSKPDIVMMHLGSNDVWSTKQPEEILGALNKLVDQMRASKESMKILIAQVIPLDPAGCTNCMRGVEDFNKAIPDWASSKSNEKSRITVVDCHKDFDVKGMTRDGVHPNNKGDEKLADSWFEPLVKVIKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URQ0</accession>
    <name>A0AAD8URQ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipid droplet-associated hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_620721</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365255.1">
        <property type="nucleotide sequence ID" value="XM_060508211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URQ0"/>
    <dbReference type="GeneID" id="85392110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="37080" checksum="A381417960B519B2" modified="2024-05-29" version="1">MAAGHGLFFFIPGNPGLVDYYTDFFDALKARIGWADGHIHVYGRDLFGFRDDSHEPFSKDSLPYDVEHQIELVFDHLASLRRTDSSRSAPGKKGEPYDFVVIAGHSVGSYIALEIFHRHLKDPSRAPHLKLLTGMLLFPTVTHISKSPSGKQMELIRTTPFLNNTAHVIAQKFLNLWPAVALRWFVGNVLGMGPKAADVTTSFLKSRDGVWQAIHMGKDEMKVITEEKWDKELWEVEEDDLGNGKRAAPRFFFFFAKKDHWVGDHFRDHFIRAREKHIENGWARVEIDDTGLPHAFCTTEKNSEIIAAKVAEWLKEVWDGLAQPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USD8</accession>
    <name>A0AAD8USD8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_615880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366486.1">
        <property type="nucleotide sequence ID" value="XM_060507930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USD8"/>
    <dbReference type="GeneID" id="85391829"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="27313" checksum="C91F2BBF2AF3C18A" modified="2024-05-29" version="1">MLGTFPFWEWGYDAEDPTLSPLFDGSDTSIGSNGAFVPHEGLEIHQAYTNVTLKLEPGSGGGCVMSGPFSKMTVNLPVVQNTDTPLAADPRCLQRDLNKHVSSRHTTFRNTTLLLTEHNTLESFWGFLNGDDRYINPFELGVHAAGHWQLGGDSGNNFFISPADPAFFLHHSQIDRVYWIWQMLDWENRQDIFGTVTMQNIPPSRNGTLDDLVDLRPLAEPRKLRDLMSTFGIGGSPFCYVYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT05</accession>
    <name>A0AAD8UT05_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_611363</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367935.1">
        <property type="nucleotide sequence ID" value="XM_060507655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT05"/>
    <dbReference type="GeneID" id="85391554"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF1">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="3">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="401" mass="44093" checksum="6CB75A588ED3F1AA" modified="2024-05-29" version="1">MGRTQPSVGQPPAAFRKAARAKKAKVTLNQLIPSLLPTHPRAQRGIDSAELIVEPKSAVKETRTPKKEGPDVSETNGALHIRLQVADTLTAAHALVTEKAEPDRPVNVSNKETRVAILNMASPLTPGGGFVNGAGSQEESLCMRTTLLPSLKDEYYRLPELGAVYTPDVLVFRDEDTDDVLEKKDRWFVDCISAAMLRNPEIERDEDTGFSHYVQEKDRQLILEKMKIVLRICQLKGIRKIVLGAWGCGAYGNPVAEVAKAWKKALLPRNDRKGKKKGNKETWSGIEEVVFAIKDIGMADAFEEAFGKGIDRDVEAEVDESDEDIDIAQRDREELQARIAELKQRIDATPNPQVKKGLDSILDGLISQLPTNSGKDIDEDEDEVDGSEDDSGDSDAGSEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTN5</accession>
    <name>A0AAD8UTN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BRCA1 C terminus domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_115244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368687.1">
        <property type="nucleotide sequence ID" value="XM_060501122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTN5"/>
    <dbReference type="GeneID" id="85385021"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035361">
        <property type="term" value="C:Cul8-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990683">
        <property type="term" value="P:DNA double-strand break attachment to nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18436">
        <property type="entry name" value="BRCT_BRC1_like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18437">
        <property type="entry name" value="BRCT_BRC1_like_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18438">
        <property type="entry name" value="BRCT_BRC1_like_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17743">
        <property type="entry name" value="BRCT_BRC1_like_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18439">
        <property type="entry name" value="BRCT_BRC1_like_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000048">
        <property type="entry name" value="DNA repair protein Rtt107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053036">
        <property type="entry name" value="CellCycle_DNARepair_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47667:SF1">
        <property type="entry name" value="REGULATOR OF TY1 TRANSPOSITION PROTEIN 107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16770">
        <property type="entry name" value="RTT107_BRCT_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="101"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="232"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="334"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="833" mass="93193" checksum="74B804F846F973FC" modified="2024-05-29" version="1">MAEQAKGLFAECTFAFVPSAHLAPKEISEYAGIVEGRGGTVLDPRRDGSLKLEAVSHIISNTIDFPQFTETQAFMIPVVNTDWIKASVKKNKQAQVRPYSPDPRMFFSKVILTTAGLPEIDKETIIGATLAMGGMEGADVTRQTTHICALTTEDPKCVIAKEKGLNCKIVLPHWFEDCFKLGKRIPEGPYLLPDPEILRHGENQGEVQAPKYEQLNGATSTSPNHLSDGPRKPATIFRDKDVMLSGDLSITPRSLEAVKQLINNGGGKVVDNVDDCDYFICQYRDGNQYVKAAQSGKDIGNLSWLYHLITHNEWTSPLRRLLHYPVPKNGIPGFEGLKICLSNYGGDARIYLENLIKATGATYTKTMKAENTHLITARSSSEKYEAAKDWNIETVNHLWIEESYAKCEMQRVTVPKYSHFPVRTNLGEVIGQTFFDEYCLRETYYPGGEEGLSPQATRKRKILEAAQENSYLHGPAEGVVIGRQEDKSEEAIDDSFMTPIRPKKGSRGKENDTPSEISTGGRSAKSKALTNLQRIAPDIALYEKEKKRSKDKQGPWGGKRAADQIDRERGRTSSPAQAMEVDEEDEDSRPSKKRKSLRPDVEMRIVLTGFTRWVNAKSKEDTERRKLRDMGIMIVQDDKPCDYLAAPHMVRTVKFLKTLAKGPTVLSSNFIDEALERGEVPDPDDFLLKDEENEAKFGVKLETAVSRARANLGKLLWTVPVYCTNNICNGPESYKAIAEANGAMFKLYRARSGTTIKPTTEEEDGGAPPEPVYLLSSNSADERSLWPKFEEMARKGHMEPRIVAADWLLDVAMKQQVSFDEKYLAKNFFQKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUH6</accession>
    <name>A0AAD8UUH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase family group 2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_717857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367384.1">
        <property type="nucleotide sequence ID" value="XM_060511994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUH6"/>
    <dbReference type="GeneID" id="85395892"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF1">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="717"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="751"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="843"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="870"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7928" evidence="4">
        <location>
            <begin position="79"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="521"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="902" mass="101452" checksum="231B0AA26CE128F9" modified="2024-05-29" version="1">MKAFKTYFTPDQASGQPAPETSKPNTLQPIAPQPKPQAAERPAPYRTHSARTSARQSTVSLALTAGMRDKHASSIIDLRADVTVHSIYQDQLRKMYASAWNLGEGVVLKKGRNDYVCAPPQLSTVPNGFFDMVTQLNVSCAMTVNTPVIQSIIHGLLSSGEPLNSIPLAGGLQLQVLQRMTDLPRCQKHHFAAFILDPPVLTVWDDDANRLHARAESLEHMIISYIWRNEGGDEEDGDEKNEKQPGVNIEELSPAALEEALRAEVRPVRLTSSIMVSAALCLSVACLGLGYRNLALESTIDGSYTRWALLAVTPLTLFISLFFFLSISGNIFQILGPISSVHANSKNYSGKAPRRLGPHRGELPHVTIQMPVYKEGLNAVIKPTVLSLKTAISTYEMQGGSASIFVNDDGMQLISEDEASARREFYEEHNMGWVARPAHNPKPTDPSVQPFIRRGRFKKASNMNYALMTSNRVEEKLKQINRGSRWSQDSEDQAYEQALAEVLEESEGRTWAEGNIRMGDYILLIDSDTRVPRDCFLDAVSEMEASPEVAIIQYTSGVMQVSDSFFEKAVTWFTQMIYTMITFAVANGDISPFVGHNAILRWSALQDAASYMEDGYEKFWSESHVSEDFDMALRLQTSGYSIRYGAYTGDGFKEGVSLTVYDELARWEKYAYGCNELLFHPFRFWLTRGPFTPLFRRFIFSNIAFYRKVTILSYIGTYYAIGASWILTLMNYFLTGWFFGYYDKYYLDSFAIFFSIIVVFPLAGNVALAVLRYRLGQKSLLGALWDNFKWMPVFTIFLGGISLHVSKALLCHFFEIDIQWGATSKEVENCNFMEEIPKIIKSFAGTFIFTALGIALIVCGYYVFPVQWQIRYFATIFPVAISITSHFCLPVLLNPALMKFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWB1</accession>
    <name>A0AAD8UWB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_129340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368556.1">
        <property type="nucleotide sequence ID" value="XM_060501201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWB1"/>
    <dbReference type="GeneID" id="85385100"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="30229" checksum="88B79572203F51CB" modified="2024-05-29" version="1">MCMKVFALQRCLSPENGGCGSYFADYLEQRECNHMAFPGLPQHNCRAVWAGFEDERSSKAIHRDEYAKRAHKLCADCRVRHRLTYLDSEAQAERRGEYSDRMKTIIEDLTRRADLGQMEFMNRVYRDMWDAALGYVQGMAKTTDGVWDGIEAALRRHFGDNGMEMIVVGHLVQDLKSAKKELLEQVMTSTREMATALVGPNMDFQQDLEAGGFRNEGYINEEWKLQRKTAVDASRAKAEAGDLESDDEMGRDYGLSGPVGQVYKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXS8</accession>
    <name>A0AAD8UXS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Clr5 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_648530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368630.1">
        <property type="nucleotide sequence ID" value="XM_060510188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXS8"/>
    <dbReference type="GeneID" id="85394087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38788:SF3">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="276" mass="31744" checksum="8B5ADA37483A82DA" modified="2024-05-29" version="1">MTKAWKEHKDVIARLYIKENRTLDEVREIMQQDYNFKASTRSYRQHFDQWDLSKYNCKKRTARRQSRDYQQYPEQQQYSPSATAAAAAAVVIVQETYPMSPQSYGSSSGSMSPESEMDSGGGRLDDVDVGQSYGGHQYTYAGQGQSQPVLHQQYTQQQQHHHQQMEQHHRQRQSWDNQVPRSMSSPWDQAALPSPPADLSGDSFFQMSGAEALSVQGNHRPQAYTSVIHPDQYRQQQQQQHYHRQQQSADPRMMPTRLLAPAPQRPGWEEGCPALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7Z3</accession>
    <name>A0AAD8X7Z3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">pH-response transcription factor pacC/RIM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_657958</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000229">
        <property type="protein sequence ID" value="KAK1706141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357789.1">
        <property type="nucleotide sequence ID" value="XM_060510994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7Z3"/>
    <dbReference type="GeneID" id="85394893"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000458">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001875">
        <property type="entry name" value="pH-response transcription factor pacC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="389"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="544"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="389"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="544"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1706141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="599" mass="65175" checksum="2652FF9A35FBD63B" modified="2024-05-29" version="1">MSAKQENESSASNSPKSSTPAPSTTTSNTSQSANSTSAEDNLICKWNACNLKFVSPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCEFCGKSFKRPQDLKKHVKTHADDSVLVRSPQDQGLNGYRAQPGKEANLPPASSSYYDHNGHIRTNSAAFAHQAGHASYYAPQPSTNYGLYFNQQPLNPPRTEYIGHHGGYDNRNKRAFDMVDDFFAHAKRRQVDPTSYQQVGRSLLPLHGALGLHAGPMPGSDYMAAPPQQHVHHQQAGGPPSGPGPMSQQYYLPPMPNARTKNDLVQIDQILEQMQSTVYENSHQATQGIHIHGQNTFDLRHSPSPPGIHRGSHAGIPVTQDGYPVSAAHMASPLTAVSSTGTPAVTPPSSTMSYTSGHSPSPSSSGMSPQSRHSSTASSVMYPNLPAVSSVFPGQSTASTLGPSFDSNERRRYSGGMLQRAAPSSPKSPIIYEDSSSVTTPKAESVASSVGSPSSESDTSEGAREREEKYDQWLENMRTIEALREYIRDRIDRREYSDEPAEKAAAEAATPAPKSPEASRLKSPEPMEVDAKPAPAAPLYPILRMAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Q9</accession>
    <name>A0AAD8X8Q9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_595603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000305">
        <property type="protein sequence ID" value="KAK1702622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357162.1">
        <property type="nucleotide sequence ID" value="XM_060506809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Q9"/>
    <dbReference type="GeneID" id="85390708"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1702622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="267" mass="30837" checksum="3059FB40B1F0E10E" modified="2024-05-29" version="1">MERLNELVEVECDQVHLHFTCVFKGSEDEQTFTTCSSCRERVVEMSRLFVELWPGDWHSGHGAYIQDSLLDTIESEKASTDGMDIASMIKFRLKYSDLADSIIKDLSLPVPSNKPCGIWSKAEWEKERRRRDDEPVFDRSWEITWRKFIDGNLVPQGTVKQGPEFIRFVQYLVAAVRQKEFITKVVHDEYNELIEKIIQYVIDARASDSELACQSAAVRQARVERKGLWRNTCLLKLRKNCETECRACGFVKPEVQAGEVNTCFQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9V6</accession>
    <name>A0AAD8X9V6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cyclopentanone 1,2-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_709234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359889.1">
        <property type="nucleotide sequence ID" value="XM_060511567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9V6"/>
    <dbReference type="GeneID" id="85395465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050775">
        <property type="entry name" value="FAD-binding_Monooxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43098:SF3">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="8">
        <location>
            <begin position="3"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1713836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="524" mass="59347" checksum="4F08142E06DFABB1" modified="2024-05-29" version="1">MDYDVLIIGGGFGGCYALHQLRQSDFSAHIVEAGSALGGVWQRNSYPGARVDSETPYYQLSLREVWKDWTWSQRFPGHEELKRYFTHVDKVLDISKDVSYNTVVVGADFDMATAKWIIETDTGRIITSRFLIPATGSSIKRYEPEFAGKDLFKGIVVHPAAWPDSGIDLENRRVAIIGSGATGVQCVQEIAKQPGVELTVYDSLKAIYKTLFKLARDSSAGLPCDGPTQVTKETTTEEREAWWEELWKRGAFNFQTGQYTDFLLDAEANDLIYEFWTKKTKCRVRDPEKRAILVPDKQPFPFGTKRSSLEQDYYECMDQDNVEVVDVKKTSIREWTARGIVTEDGKEREHDIVVLATGYDSMTGALTSMRLRGKDGIDMKERWRQGVWTYLGLMSRGCPNMFMIYGPQAPTALTNAPVFIEQQVDFIMDFLVKLRTENITFIEPRRSAEEHWKKTVQAIHEALLFSKSDTSWYVGGNIPGKKKEQLNYLGGIPQYLKECHEGTKDWSNFDVVAGAGSAIKSKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA35</accession>
    <name>A0AAD8XA35_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_735456</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000177">
        <property type="protein sequence ID" value="KAK1709980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358676.1">
        <property type="nucleotide sequence ID" value="XM_060512968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA35"/>
    <dbReference type="GeneID" id="85396866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="427"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1709980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="57896" checksum="F34BBDC0CAC96619" modified="2024-05-29" version="1" fragment="single">MGLDDLFHHFDKSEYTARMKSSTDNELVQRDVVKTRQHLTAYFSGGTYLGMAIPTCGASLIMAPLTARRYYISRQKLKIVQAELERRNIPLYETRKRDVAISALTGTIGLAVGIATLGVTDGLTDSLTFTSLGNSGASGASGASAIDALSADPFSAVGDAVQGAVAQFQEVSINITGDTMGQTILPEGQIVELHDLETGATADMIVATPEVAGAWNMGVHLAQSAEKALAQSAFLDAAGSALVMEAVAGYGKSRGRCCPRLLGVFGAMNCDCCGEHIGKRQYHHCCLCASDDFDLCQACYSKGSRCLSASHDMTLLQLATNQDLSSEMPIVNLYPNWKHEAIEFVTRSQLSGGEYTLFGCDHCGEAIRQGNCYHCFHCGNYDSCERCYKDGSSCGTIDHVLTALVCAVDCSSHRYWVSDCRRSEGMCPGIQCSSCHQLVTQGRYYHCCNCDGDDFDICHACYKSGERCKNPTHHTLQLHLGGNDRFLLEYPETCARRKYTLQSSTVYCDHCSDKITRGSFYHCCKCEENYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAM7</accession>
    <name>A0AAD8XAM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_531518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360699.1">
        <property type="nucleotide sequence ID" value="XM_060503325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAM7"/>
    <dbReference type="GeneID" id="85387224"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="220" mass="21386" checksum="7890A961DCB876F6" modified="2024-05-29" version="1" fragment="single">GTREGSSNTSGNGEIRDGGEGGLGKDSSDGADDREGRLSEDGTDGAGNWKGAEAGSCKGSGRSSGDRYVGNGRDSSLENNNGWDGGLKDNSSNALSGSGGREGDGLSAGEAAHDATGDGDVGNGTNGRLQQHGANASGGRESGHRGASEGSNDTSNDRSVRDNNGAGNGCLKDHGSQASSNSRQGGCLSAGEAAGDSAGDSEVSSGQGGLKQDGSETTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB35</accession>
    <name>A0AAD8XB35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_706722</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361194.1">
        <property type="nucleotide sequence ID" value="XM_060511531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB35"/>
    <dbReference type="GeneID" id="85395429"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="505" mass="55945" checksum="E5BF66081C7AB38E" modified="2024-05-29" version="1">MEAAKDNKITPATRAEGSLRDGSVDGENVKKNNYDDDVVQVVDKAAERALCRKLDLHILPVLAVMYLFNALDKGNLGNAETDGLSTDLGFKDGQYNLIVSIFFVPFVAAAPFVALIGKKFGPAIVLPILMFTFGTMTMLMAAAQNFGGVFALRWFLGMAESAFFPLVIYYLTTFYRRGELARRLAVFYAASNIANAFSGLLAFGVFHITNTKLHPWRWLFIIEATATILFSFFAFWYLPRSAAEAKFLTEEQKQLAHHRIRVDSSSVVGEKMKIREAAKVFKHPTTFGFLAIEICLGVPLQSVGLFMPQIVQRLGYSTIKTNLYTVAPNVSGAAMLLILAFLSDWRRLRFPFIALGFMLTFIGFIIYAAIDDVEAEIKLAYYACFMMTWGTSAPSVLLSTWYNNNVVNENQRVLLTSIGVPLANLMGLVSSNIFRKPDAPKYAPALITTAAFGVAGASCALALGFFMMWDNRKRNRAEGVTLTASEVPTSKLGDGPKSPHFRWFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBC0</accession>
    <name>A0AAD8XBC0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA N-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_643928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357715.1">
        <property type="nucleotide sequence ID" value="XM_060509707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBC0"/>
    <dbReference type="GeneID" id="85393606"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1705936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="243" mass="27326" checksum="AE57303918E9B1AD" modified="2024-05-29" version="1">MSNQDSKDTHYHVSICAVEPSDVDDLVAIHTAAFESDQFSNLMLLNREECAHQNLMRKSVLYWLTNPSTTKLFKAVEGNGKLLGWSCWVKKELEQKKSDDSKSSEAPSDPNLSKEKARSGKDMPREPARVLGGIMHKDMTSWESRQLEGTKYMVLQALATHPEYQGRGIGTRLLQHGLEKIDSQSLACWIHASPSSYRLYEKAGFQEVGKSEYDLAEWAPVGTGGEVGWGTYTFRYMLRSAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBS6</accession>
    <name>A0AAD8XBS6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000171">
        <property type="protein sequence ID" value="KAK1710353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358823.1">
        <property type="nucleotide sequence ID" value="XM_060509497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBS6"/>
    <dbReference type="GeneID" id="85393396"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="92" mass="10596" checksum="9BA65B91E8BC3C57" modified="2024-05-29" version="1">MQPGLPGSWTVDEQQSSADPVSKWANPLMVESKGKVAYILTFVTAGERLRSAGHDKRQRRWDDEDEDHGRRAEIRHARANAKIRRETHFLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBV3</accession>
    <name>A0AAD8XBV3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_584159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362004.1">
        <property type="nucleotide sequence ID" value="XM_060505734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBV3"/>
    <dbReference type="GeneID" id="85389633"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="61085" checksum="C30F17470B66DEF6" modified="2024-05-29" version="1">MPNTGRPSPNCHLCRSRRVKCQRCIKYGVQCPGYRDDDGMRFQNADPTSFERRKKKRNHQQHPHQHQDQDDEAIRQPSRQSTPATSITTDTTTSTQLSVALPVLKTLRQHWTAESIPLVLGFYESLDFLPGLFRGAGQDHCLVLTGQVFTRAYMINKFRPRADYRELSIVLGHALAAVQEAIRNPKTYTSDSTIVALMIGGLERRSFITNKERGSSPEVPWHIHGQGLLSLMRARGDRQLYTRSGRQIFWVMHNMIVSKTLKTCSVLQVQLTIANTPCPPDFERWLDIIEATLQPSEGLLLHTARYLSAACSLLSKLIPLTLSGDASRAREAYPALIAESDRADLAMAEWMHAAPEFQIEPGPMWGYFWNSWRSARIKVHHMIILISNLVEYGEPTLVPEDYDADCGGCPLLNPEVLHARREFCMGIIATAGRDVVEGIPRSLGGKMPDLDPDLPSSYFDGVRLIWPLSHLYILPTAPRHLRIVARDALLRIAKEKGILTALKPRAGGMLFPEAALRGIPVDNLEDVMEGGGRVHQIATKAEAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCA5</accession>
    <name>A0AAD8XCA5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_629043</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362499.1">
        <property type="nucleotide sequence ID" value="XM_060508741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCA5"/>
    <dbReference type="GeneID" id="85392640"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03876">
        <property type="entry name" value="M28_SGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02130">
        <property type="entry name" value="PA_ScAPY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000054">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041756">
        <property type="entry name" value="M28_SGAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF17">
        <property type="entry name" value="AMINOPEPTIDASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041772196" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="10">
        <location>
            <begin position="166"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="11">
        <location>
            <begin position="277"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="523" mass="56421" checksum="4E90AEC269C38A7E" modified="2024-05-29" version="1">MAGARRLQLAGLALLGGVSALQMQMQVPEQQAPMIADDAPVVATSPSTTSSSSSKKPLVETEALQDTISADNLLARAKDLYDIAKLGEEEYNHPTRVIGSDGHLGTLEYIYFELAKLGDYYKIWNQTFPAVSGNVFESRLVIGNDVPKSASPMALTPPTKDKEPVYGDLIFVENNGCDASDYPSKVKGNIAFIRRGTCAFGAKSEQAGKAGAIAAVVYNYETETVHGTLGTPSPDHIATFGLGGDDAKPILEKLGKGESVDAIAYIDAVVNTIETTNILAQTIEGDQNNCVMLGGHSDSVAEGPGINDDGSGSLSLLEIATQLTKFSVNNCVRFAWWAGEEEGLLGSDYYVDVLPEEENQKIRLFMDYDMLGSPNYAYQVYNATNAVNPTGSEELRDLYVDWYKAHGLAYTFIPFDGRSDYDAFIRNGIPGGGIATGAEGIKTKEEAKLFGGKAGDWYDPCYHQLCDDVGNVNLTAWEINTKLVSHSVATYAVSFKGFPERTKAAVASTYSKKTKYHGSKLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCV7</accession>
    <name>A0AAD8XCV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_588564</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360083.1">
        <property type="nucleotide sequence ID" value="XM_060506147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCV7"/>
    <dbReference type="GeneID" id="85390046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1714940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="437" mass="47036" checksum="4413BD055CF384CB" modified="2024-05-29" version="1">MFSRHDSQPRQTLITAFIAWKALLLAIALGSAVAPSYDTSTTLMLQRNESDISLVTRLTRWDALYFTQSARRGYVFEQEWAFNAGLPLVVSGLIRVARLFGFEGDGTGALEAAFSIVVAHVAHLFAALMLYELTIKLFSRPRLAFLSTLLHILSPAGLFLSAPYAESLCAFFSFAGYYVLASASTSTKGSISWVTAQVLAGAIFGLATASRSNGLLNGLPFAVECLMILPPLLASPTSLNNIAALFGSVTGGLLVATGSVVPQALAWLRYCSGASEARAWCQRTVPSIYSFVQEHYWGVGLFRYWTLSNVPLFILAAPVLGLLMVSGWEVINRPSGLARSPTAEKQQQGQSGTTSVLVGSMAAAQLLLAALAITTYHVQIITRIASGYAVWYWWVAGCLLDDGANGKRRDIGGKVVMFSVMYAMIQGVLFASFLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD55</accession>
    <name>A0AAD8XD55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_627807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362887.1">
        <property type="nucleotide sequence ID" value="XM_060508659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD55"/>
    <dbReference type="GeneID" id="85392558"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF5">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01420)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="8"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="36683" checksum="EAC555F0E8D7F22B" modified="2024-05-29" version="1">MREAIFDGNLEVQIHDIPIPTPGPGQILIKTVVSGTNPKDWKVPKIWASNLPPLNHGDDIAGFVQGVGEGVLGFKEGDRVAAFHEMNTPHGSYAEYSIAWAQSTFLIPERTSFEEAATIPLTAMTAALALYQKLDLPLPWNPAKISLPLLVNGGATAVGAFAIKLATLSNIHPIIAVAGSGSPYVETLVNKEKGDVVIDYRKGEHHVLEQICLAAGGQPIINALDGVSEEQTVRIVAKALAPGGKISVFLQTSPSDIKAEILYTMVGTVHASNETPGSPLGDKEFGSVFYRFFGLGLKEGWFNGHPYEVLPEGLASLEKALKDLEAGKVSARKYLLRIEDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDN6</accession>
    <name>A0AAD8XDN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Duf1237 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_582982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362516.1">
        <property type="nucleotide sequence ID" value="XM_060505605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDN6"/>
    <dbReference type="GeneID" id="85389504"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008313">
        <property type="entry name" value="GH125"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047:SF2">
        <property type="entry name" value="DUF1237 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31047">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 157 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06824">
        <property type="entry name" value="Glyco_hydro_125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01149">
        <property type="entry name" value="DUF1237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="75172" checksum="F0947934ECC32668" modified="2024-05-29" version="1">MPAFTVLSGGIQTRRARVVFIALLIIIFVLFLNNSGLAGGGSYLDSARSAAAGVSNGKTTTTTGGDAGKQPLGNQDKDKELPVAHGEPDTAADKLKADAEGQDSYRNKDEELAKQPPTDTGRPGDPIPSAPASSPMPPTPPPAADCESFENWMRSKPGPLSEGKRKFPLNRPRPECRTFRLPAMDNLITRMKGVIKDPDLYRLFENAYPMTLDSMVKWRGYANETDKATGVSKATDQELTYVITGDIDALWLRDSAEQISPYLPLLEASRDPNSLASLWRGLINAHSRYIIISPYCHSFQPPPESGIPPTHNGAYVHNHPMPAYDPEKVFDCKWELDSLASFLKMSVSYAEKTGDWQHFNKYHWVDAVEAAVNAAGAMRLGTYSPEGKVEKSAWTFTGWTNRGSETLTNDGLGNPIKENGMIRTAFRPSDDACIFQFLVPANMMWAKYLESASEIMAKLDGEKAKNLTLEMRAQAFGIRQGIEKDAIVHRPGFGDIFAYEVDGYGGANLMDDANVPSLLAMPLWNFTHSNFKYPDPPKGEKLHDYTEVYRNTRKYVLSDANSYYMKGPAISAVGGPHVGPGKAWPMAAVIAAITAYDPISGSKDVEKDVEEQLRMVLDSTAGSGVLHESVNSWNENDWTRAWFGWANGLFGELVLKMEEEEKKKKGGSGGLLGKSWQGSSGAAPAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE06</accession>
    <name>A0AAD8XE06_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="11">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_558940</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362906.1">
        <property type="nucleotide sequence ID" value="XM_060503546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE06"/>
    <dbReference type="GeneID" id="85387445"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF34">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="12">
        <location>
            <begin position="13"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1722851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="25074" checksum="57BDED7E3F92C26F" modified="2024-05-29" version="1" fragment="single">ALVGAFAASALAHGTVTGFKFDGAYEAGYKLDYYYLKQNGGTPPSISAWSAENLDNGFVDGTGYASADINCHKNGAPGAVASTVAAGGTVDFEWSAWPESHFGPVLTYAAKVDGDDWASVDKTTLKWVKIDESGIDIATQEWAATKLIANNNTWSTTIPSDLAAGNYVLRHEIIAMHGAGSLNGAQNYPQCVNVKITGSGTANPEGTLGTELYKNTDAGIQFNPYATISSYTIPGPALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEN4</accession>
    <name>A0AAD8XEN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_719541</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365019.1">
        <property type="nucleotide sequence ID" value="XM_060512187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85396085"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000838">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="792"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="842"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="918"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="942"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1012"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="184"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="527"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="829"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1107"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="483"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1341" mass="146277" checksum="0350AE2441086597" modified="2024-05-29" version="1">MFLAHLRTAIAAAALTILESVFVAGLSFTEHSRSLSPSLLLSAFLVLSTVFDAVRLRTLWVKSVGTPIVALSTAAFGLKIALLVQEEASKRRWIIDNSSECSSEETAGLLNRVGFHWLNGLLLNGYSSPLTIAKLPVIDRQLLSDPLWDRVGQKWRNSPKQANNALLGTIFSALKWPILAPVPAYMILVGLQLAQPFMISTIMAYLANPVDHTEDQRNIVYGLIGAYGMVYISITIVTAGCQHLVFRYATMMRGCLVLLIYEKTTSMSITDAEEAAAVTLMSTDIERIVSGMSKIHESWSTLLQMAVALTLLYRQLGVVFIVPLVLFLICAVGAGALSGSAGGFQASWMAAIQKRVAVTSSVLGSPKGVKLSGFTDKMFQIIQDLRLKEIASAARFRTMLLVIVTLSYAPGSISPVVTFGAYTAIAQKDHTTLDLNRIFTSLALLSLVTQPLNELFAHLPNIVASVACFGRVQAFLLSPETSATSDVRSSSPTSESHVDTSGRQQSEKQPSATITSHLDPQASGHAIEIRNARFGWKADAEPALTNLTLDIPHGKLTVIVGPIASGKSTLLKAILGETPVAEGTINRASDNIAFCDQVPWLTNETLRRNVTGFSHFEASWYSTVIRACALEDDIATFPDGDQVMVGSKGVTLSGGQKQRVAIARAVYSRRDIILFDDVFSGLDFETQTRVFRNLFGVSGLLKQHKVTSLFAYYIITLDGTGTVASRGPFEELNKQPGCISKFGLITNEDAIQGDVVKDDGQSAFKPEHKERIADNSVDEETQRMGDRSVYKYYFQATGPRSVLIFITLQVIWVFLTKFPEIWLSWWGEANDSHPNQETGKYMGVYATLQVLSLVALAAVCWHVVLRMAVASGVRLHWILLEKTLRAPLSFFAATNTGSIVNRFSQDIQLIDAELPISLLNVAANGLICIAQALMIIPASYQVIAVFPFLGGILWVIQRFYLRTSRQLRFLELEAKAPMYGLSTIRAFGWQKDLTNLMRDRLDTSQKPIIQRWLTLVLDLTVAALAIVLISVAVALRGRVGAGFAGVALYNIMGLSSAMKAAITVWTVLETSIGAVARVKTFAEQTPAESQAQESQTPPDSWPESGAISFHNVTASYGEGMDNISSKVSFTVLPGQKVGICGRSGSGKSSLLLTLLRLVDCNEGQVIIDGVDVVTMPREVLRQRLNALPQEPPFFSGSVRLNCDPEGTISDEIVTEALRTVGLLGVVEEKGGLDAEFSDDFFSHGQKQVFCLARGILHPAKIVVMDEATSSVDVDTEKKMMNVIHERFADATIISVPHRLDTVLDFDKIIVLDKGVIVEEGCPAELLSRASAFRTLYETFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEP8</accession>
    <name>A0AAD8XEP8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metalloprotease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_577561</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1725009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365064.1">
        <property type="nucleotide sequence ID" value="XM_060505031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEP8"/>
    <dbReference type="GeneID" id="85388930"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042130471" evidence="10">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="198"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32431" checksum="5C8E5AE41FFA1A13" modified="2024-05-29" version="1">MRMKFLLTCCAGLATASLVVAQEKCGSEQPGPEAYEAAVALRAAQRAEGLSASFLHKRAEGLLVSTYLHVVEDEAHRGFVTDTMISDQMRVLNDTFAPHNIQFLVKETTHTVNDAWTMQARIKEKAEALRRGAYDDLNIYFETGLMTNPNSATGICSFPVEDPRNTGINGTSWYTYDGCHVSVGTMPGGPGVPWDPEDNLGKTATHEVGHWFGLFHVFEGFDCEREGDLIDDTPATKIATVGCPVSQDSCPEQPGLDPIHNYMDYTKHACLSEFTPLQEERMYRSFNTLRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XET6</accession>
    <name>A0AAD8XET6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_312896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365184.1">
        <property type="nucleotide sequence ID" value="XM_060502315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XET6"/>
    <dbReference type="GeneID" id="85386214"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="253" mass="25294" checksum="E82F89070CF13E7F" modified="2024-05-29" version="1">MPPKSDSAIHTSLILEILGVYQQLLAITLVHQNRFSNCCSTPIAIMSRYLLPILAATAVLAKTDLAGCASLTYTYPGPSGVSIKTVIHYVPETHEICTPLDCGGTDPASGKKIPGCPGYSGTETITMSFLSSCATVKPPTVTITQTLATPGSNSGVGSTTVTVTPPTTTSTIIKTVTTSVTSPLSSLTPSGVTTRTGGTGSTLITSTEGEDVPTGTGSGAEPSSSTVPAGAGSTARAGMAAVLGVAAAVVVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEX6</accession>
    <name>A0AAD8XEX6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_534185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364777.1">
        <property type="nucleotide sequence ID" value="XM_060503340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEX6"/>
    <dbReference type="GeneID" id="85387239"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF1">
        <property type="entry name" value="LOW AFFINITY AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="13"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="470" mass="49953" checksum="3F5B43EEF31AC898" modified="2024-05-29" version="1" fragment="single">RPEPLSSAKESFLVTVVSLYQFLMFAGLAQGVAPALTIAESFPDIPSGQHSWFTAAYTLAIGAFALTAERLGDVFGRKPVIITGCLWFALWSLLAGFSVNVQNGGADGTAYLCFCRAMQGLGPALCVANGFSVLEKALPPSQRKDMALAFFSAAAPVGFVVGAVMSSLFAYNDSWEWSFFVLAAVNISAAGLSLLVVPRQAPRKGPYDHTIWVQLDISGTLLGSSGLALFSFAWNQAPAVGWRTPYTYFILIIGAMLLAAFFYNETAAANPLLPLRALTSRPNLILGCTAAVWACFIIWAFYSFQTHEVLRSWDPLLASAGFVPVAVEAVAVGLLLAYLMPGEEVYWAFFAAVLSFLLASILMATAPSDQTYWANTFVSTLFAPLGMVLTTPLATILLRQNLADGHQGVANGLVLAVSSYAMSLAMGIARTVEVQVDSSGTEKLSGFHGAQYLGIGLSGLAVICATVLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG67</accession>
    <name>A0AAD8XG67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_753397</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363653.1">
        <property type="nucleotide sequence ID" value="XM_060514349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG67"/>
    <dbReference type="GeneID" id="85398247"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF27">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32713" checksum="01EDD7D2577D84D8" modified="2024-05-29" version="1">MPTLESHNGYYLWHYVPSLVAAIIFEVLFVLATLFHAYKIARTKTWFCIVFVIGGILEIIGYAGRAIARDRTGEVGPYVMQSLTILIAPALFAASVYMTLGRIIRSVHGESLSVVRINWLTRIFVTGDCFSFLVQASGGGLMVKDGSQKMGQNLIVAGLVIQIVLFAIFWVTAIVFHSRLAKNPTQASLAGHSPWKSGLWMLYIVSACIMVRSVFRLIEYVLGGDGYPLRHEWTLYVFDATLMFFVMVAFGFRFPSAFQIRKGGSQSASDVENYDLAVESEQHQPGSMRKTMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGH8</accession>
    <name>A0AAD8XGH8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_753079</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364013.1">
        <property type="nucleotide sequence ID" value="XM_060514299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGH8"/>
    <dbReference type="GeneID" id="85398197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000146">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000181">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000239">
        <property type="entry name" value="C2H2 type zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="94"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="206"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="354"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="633"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="656"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="687" mass="74372" checksum="40375C93553869D9" modified="2024-05-29" version="1">MDQQGQRGRSPSAGHQQPHIRHPSHSPSPNPFQPNTEASIGLGLGLDQSATQAFNGAASADFSSFNNTNNFLNGQQPNQQSYNQSGAAFANQNQAGFLDPNSFPSGDFALFPNAGQNDQQFTTGVFDQSLNPGDMNNMAMPQSHHSPTPPHLLNPDPHQTPSAHQSPAFNQHQFSSPPSGAGHSRHASLGPEAALLPNQLNEWSQPQFRGHRRSPSEYSDVSSAAPSPNLVSADSFDGIDQSHSPMQRPQDAGLYQQIQGFDNFTISDPALGSPNLQGRSPSHSPAISPRILPQSMPELNQPTNFGLQAQNAGFVSGTGYTGQEAFPTLQQPEMPQAPAINIEFAPTARQNNFEQPKNQMDQDSLTPPERGRPRSRPRAVTDPFNSSGGGMVRQTSAGSLSPHLGSDLSGRDSSRSLSPLDRGAVSPSRRRQSTSAVPNNVIALRLADPEYQNAQDNGNSKRVQKHPATFQCTLCPKRFTRAYNLRSHLRTHTDERPFVCTVCGKAFARQHDRKRHEGLHSGEKKFVCKGDLKAGGQWGCGRRFARADALGRHFRSEAGRICIKPLLDEEMLDRQRAWQEQRMQQQNMQNMAAGMGMEPGYPMDAGGQYMLPAALLAQYPALAQMNWSAQDASSGLEDDISGRSSFDASDYEGDDGGYVSGPGTGFGEGGMGQNFGEVGYASDYGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHQ7</accession>
    <name>A0AAD8XHQ7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_749752</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367747.1">
        <property type="nucleotide sequence ID" value="XM_060513810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHQ7"/>
    <dbReference type="GeneID" id="85397708"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000075">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1727692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="78" mass="8662" checksum="BCF4ED3036979EE9" modified="2024-05-29" version="1">MAPGQKAYPRGTVKKIIKAHSNCNLSKNVDVMIYLDYVLFMQTLVKEAAIESKKSGERGITARSVKKVTSDTLTKFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHX3</accession>
    <name>A0AAD8XHX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367927.1">
        <property type="nucleotide sequence ID" value="XM_060504425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHX3"/>
    <dbReference type="GeneID" id="85388324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="5">
        <location>
            <begin position="90"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="377"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="55129" checksum="902AF934F07C39CD" modified="2024-05-29" version="1">MNSGSRLGFAFAAIPGPTIIDPQDLSLVKMVLSTALTVEAGGSSQLGRSLFLDVRKSSHDKLWESASIKSTMLYILLAVYSFMTGDDLQAWRLVGIVARWCLEMGLHQSATISKTFKDAGKRKMAMRLFWCVYTLDRRWGFGAGLPFVMHNFDVDQQLPEPDQDVPYLRAMVEYSRIGDKVWATSYNSARATGAIRDDEISYLLYRIDQWYEDLPEDLRLSSNEQTASPNTNSATSRGLQRLQVLLHLRANQMKILLLQPFLHSTSSLKSNKSKVQSLVNLAKDTIQMLDSLNKSTDVYQNQQMCFNHFLVSALGVIFLVVALSPTEHGASVRDEFHTALDLIRGLSARSYVSSRLWRRISDLRLAWRKLGLNAPHSREVREPSTQQDNALVTPPTSSGGMDIPPGSVPTTVDDGLRGPELDTWPAGSGEPFTEAQMAQELNDFFNSIDGGGDFGIPLPVLGTDGDGLDPERGPEDAFLVDDMNASMDVSHLFVDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIC4</accession>
    <name>A0AAD8XIC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364540.1">
        <property type="nucleotide sequence ID" value="XM_060510505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIC4"/>
    <dbReference type="GeneID" id="85394404"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF195">
        <property type="entry name" value="ACID PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041988722" evidence="1">
        <location>
            <begin position="21"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="56504" checksum="10D991F5E7B0B9A3" modified="2024-05-29" version="1">MAPKASTLLTGLAVFGTGTGTGTSAGGVVNAAGGVDLSWYAPARAEVNNLTAVINGKGVWGFIYDTSETPDDRYGQYNWCNMPHVRKTEYVKPSDDYELKYVELVHRHHKRTPYASNAFPVEPYQWNCDDQGLFYYGEPFASSNKPAKTYWKVYISPVNPFVPAGWIGTCQFPQITAQGLDDSWVHGADLYGVYHDLLGFIPGHDTVNSPEWHRKIKYRVTNNQITSQVAGMVVNGMWAATDSLQLNIQAAGVDSLEPQYSCPAGYALFNRIKSASNAAWAQHLAAAGPLYAVLDDISGVPADDEGFHASLDHYYDNLSARQCHDKPFPCKLVGGANSTTCVTQDLADAAYRLGHWEYSQLYRDSPDSLAASVAAWGVWVAELAVHLRAVVDGTSETIYFHNVAHDGSVSRLLSILQLDHMVWPGMGSEVVFELYKKRGADEGAAAAAAAAAKNPPTATSTSTPGSVESGWYIRVLWSGQVLKSSHPALGLMDMIPVETLLSYFDGLVGENASLIKGKCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIC7</accession>
    <name>A0AAD8XIC7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_751337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365948.1">
        <property type="nucleotide sequence ID" value="XM_060514039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIC7"/>
    <dbReference type="GeneID" id="85397937"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="439" mass="48317" checksum="ABFEEB6051A47F9F" modified="2024-05-29" version="1">MKVAVIGGGPAGCTAAYTLRKAGCDVHLFERDNRIGGRTSQVLKEGFNLGTGALFLMGGIYSRTTAILKELEHHKDLVSWKPITHVVDWDRQRYIARFDKVTSFIQLPVFNLLDKLRIGISIIMQLFSPGPKSLFDGAELAQYDHGETLDTWSDRVLGKKGTNHLTLPYMGFLYAVPLHWQSTPLFQGVSQQFYKLSLQVPPEGVGQFSQWLVEGSPGLDLHLSCPVNAVRTRDASGYFVDAGGKPYEVDALVMAPEPGVAADLLHNIIPTKSAAKLRNCRYSEYAHVQLCYKNNPWPNFPASVSLPATNLRKWGACVLLSHRHPNSVPVGGEAVGVYFYTPPLADMEDEEIKNEALMAVTEVFGAAPQPDFIEIFHYKRGLSLSPPGHFATMDSLHTEMPDGIVLAGDYFAHAGVELAVLSGERAARQLLGDWPSERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJD1</accession>
    <name>A0AAD8XJD1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_189064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367838.1">
        <property type="nucleotide sequence ID" value="XM_060501581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJD1"/>
    <dbReference type="GeneID" id="85385480"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041964280" evidence="3">
        <location>
            <begin position="25"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="518" mass="53848" checksum="AC23D144742A3EDB" modified="2024-05-29" version="1">MRAIACSLCVLYLGVDLLGGAVEGAEFKRRDGVHRLEKAHVTVFHDLNRRGTTTCATGYSACAASLDGGCCASGYACATDSCYATTSAAQTCAGKPGYYQCNTVLGGGCCPEGYQCQRGSNCVPASGVIYSQSCPASYYLCPASLSYGCCRDGLGCAISACYSTEPSTVTETTTITTTNDAAQAITTTVTATAVLTPSRPTTAPIVATGATDPDQVVFKYYPSTVPKERPISSGDGNSDGLTSGQIAGIVAGGVGLLIIVLVAAWIIIRHLNKVVQAVETSNKGTSSGAKSRPSMYEFKPTPSEVDDLSIDPLMMSPRPSHRRHDSDTTADLTPSYRGTPGSVGDYQAVPQGSGSDRHASYDSAYTGGYFDVAPDRSQRASQGSSAWIGLHRGSTDSQGTYAHLRHWSNASEASSDHGSAGTRTPLQELDSTPYVPELAASPVPDAVADTRRRSGSGLSGMSRPPAVHQRRRSSEGGHGRTRSDSSAPAGLSVVNEASELIGHYGPTDRANGQTSNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJG5</accession>
    <name>A0AAD8XJG5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dockerin type 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_750875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366565.1">
        <property type="nucleotide sequence ID" value="XM_060513978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJG5"/>
    <dbReference type="GeneID" id="85397876"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15892">
        <property type="entry name" value="BNR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="51698" checksum="4028F6888A136DC5" modified="2024-05-29" version="1">MSLSEVHRLQAPVVTVLGRDPAHRECVLNGNAFQQDAIISFKGWQYAVFYSSCSSSNLEETTQLEPLFVCLARRKLPNSEWQTIIFDDYHQTTDDGHNTVQMGICPGDGTIHLSYDHHCDILRYRHSIKGIASDPERSRWSKDVFTPTLDHVPGIPQPHKSFGYVTYPRFGTLGDNMFFSIRNGKAGLGDDLLYIYHAETGLYEYAGKHLKGIQNNPYVHGMDYRDGKLHLTWVYRGFVHYDGWDDPLDTKHKQQAGPNGAENNYSICYAYSDDGGYTWKNGQDKTIASLRDRGSITPDCSGLVAFDIPKGRGLTNQEAQAVDQDGGVHVLNRDTMDAENLWKHYYRCPDGRWTQHAIGPVPSPRRGRLAISKTGDLFLILPNPTNSSLRILRSPKAKDYAESVEIWNGIGFIGEPLVDVKRLEEEDVLSIFAIIESATSSEDRRVVVLDFQVQHSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK01</accession>
    <name>A0AAD8XK01_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="10">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_570308</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368605.1">
        <property type="nucleotide sequence ID" value="XM_060504287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK01"/>
    <dbReference type="GeneID" id="85388186"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04902">
        <property type="entry name" value="ACT_3PGDH-xct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12173">
        <property type="entry name" value="PGDH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.90:FF:000003">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000021">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF22">
        <property type="entry name" value="D-3-PHOSPHOGLYCERATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="11">
        <location>
            <begin position="23"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="12">
        <location>
            <begin position="124"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="D-3-phosphoglycerate dehydrogenase ASB" evidence="13">
        <location>
            <begin position="346"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF19304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1728550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="567" mass="60178" checksum="0BA082E39D652F36" modified="2024-05-29" version="1">MAPSAIEKITSTVSSFASDRLRILVPEKVSSDGLALLKDKYDVDNRAGLSPEELIEAIPNYHALIVRSETKVNANVLAAGRKLRVVARAGVGVDNIDVDAATNQGIIVVNSPSGNIVAAAEHTIALLLATARNVGRADTTMKDGKWERGKLVGVEVGNKTLGIIGLGKVGMKVARMAIGLGMKVKAVDPYASAEIAGQANVELVADLKSLLPIVDFLTIHTPLMASTLDLLKEEEFQQMKKTARVLNVARGGVYNEAALLRALDEGWIAGAGLDVFTAEPPVADSTASQLTRHPKVVATPHLGASTVEAQENVSMDVCTQVSEILRGGLPTAAVNAPLIMPEEYRKLQPFVRLIEKMGGLYTQHFVGSRGGMIGGRKFELIYQGDLASISNTRPLYAALVKGLVSSISDSGGRDVNIVNASLTAKEKGIIISETHSGEAKNAVYASLVTLRSHGADGEQVIEGYVSGQSIYISKLDRFSATFQPHGTMLVLHNYDEPGKIGGVGMVLGQHGINITFMQVASLDGKERKAEGGNEALMILGVRGEISGKVVDDLQREEGILNVSLVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK41</accession>
    <name>A0AAD8XK41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Family 31 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_608354</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368893.1">
        <property type="nucleotide sequence ID" value="XM_060507475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK41"/>
    <dbReference type="GeneID" id="85391374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF67">
        <property type="entry name" value="ALPHA_BETA-GLUCOSIDASE AGDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 14 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042219981" evidence="15">
        <location>
            <begin position="18"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="17">
        <location>
            <begin position="96"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="16">
        <location>
            <begin position="272"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="18">
        <location>
            <begin position="724"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1728838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="921" mass="103130" checksum="8BE1A15DCE48F6E0" modified="2024-05-29" version="1">MARKLSVLGLLSAVASAAVIRRDYPSDDALSKCPGYKASNVQLSSTGLTADLSLAGEACNAYGTDLADLTLTVEYQTDTRLHVKIQDAANQVYQIPNSVFPRPEATSLTIAESKLQFNYTENPFSFSVSRSDTGEVLFDTSGANIVFESQYLRLRTKLPENPNLYGLGEHSDPFRLNTTDYIRTLWSQDSYGIPSGANLYGNHPVYYEHRKNGTHGVFFLNSNGMDVFINKTEESGQYLQYNTLGGVLDFYFVSGPSPIEVAQQYAQITGLPAMMPYWGLGFHQCRYGYRDVFDVAEVVYNYSIAEIPLETMWTDIDYMDRRRVFSLDPERYPLTKVRQLVDKLHENDQHYIVMVDPAVAYVESPTLQRGIDDNIWLLRSNGSVWIGVVWPGVTVFPDFFAENITSFWNNEFAQFFSADKGVDIDALWIDMNEPSNFPCYFPCDDPYGSAVGFPPEPPAVRENPRPLPGWPCDFQPPGTDCGNNQTKRSDVLVRKQMSPRIVPAGQTFDNLMLAERQSSGDQKGLPDRDLLFPKYAIHNKAAWDTESNAARGGISNKTVNTDVIHQNGLAMYDTHNLYGSMMSSASRVAMEARRPGLRPLIITRSTFAGVGKHVGHWLGDNLSNWQQYRVSISQLMQFAAVYQVPMVGSDACGFGDNTNEQLCARWAALAAFSSFYRNHNSIDSISQEFYRWDTVADSARKAIAIRYRLLDYIYTALYQQTKDGTPLINPLFYLYPQDEKTFGLDLQYFYGDAILVAPVTEENSTSVDVYLPDDVFYDWYTHETIQGTGATISLTDKDYTTIPLFIRGGTVLPLRANSTMTTKQLREENFELLIAAGRDGTAKGQLYLDDGVSEEQAGITLVTFDYKDGKVSVDGEFKYSTPLKVSKVTLLSGGTTAKRQETIKTIAVEYALTGPFVIELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKQ6</accession>
    <name>A0AAD8XKQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_789179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369220.1">
        <property type="nucleotide sequence ID" value="XM_060515692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKQ6"/>
    <dbReference type="GeneID" id="85399590"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="75"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="173" mass="18880" checksum="7C399BA447F8C232" modified="2024-05-29" version="1">MGIPSQFKSVFEAKAGEERIQAWLNLDKDDAGNFKFGNWMGALIPSIALLSTSLTPTPRATFAFTVLPEHCNRAGNLHGGAAATLFDSLTTMPLALVNDKPGYWQFLGVSRTINCSYLRPAPNGEECLIECEIVQIGRTLCQLRGTLTRRSDGVVLATCEHHKFNTDPPASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL39</accession>
    <name>A0AAD8XL39_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_568735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369431.1">
        <property type="nucleotide sequence ID" value="XM_060504114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL39"/>
    <dbReference type="GeneID" id="85388013"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052965">
        <property type="entry name" value="Pigment-catalase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694">
        <property type="entry name" value="DESICCATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694:SF26">
        <property type="entry name" value="OS05G0151100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041916276" evidence="1">
        <location>
            <begin position="19"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="310" mass="33028" checksum="50F3CB9BD11B8808" modified="2024-05-29" version="1">MRTSSIILAAASAASVLGAPLEKKANYDPLPGGDITILNYALTLEYLERKFYEEGLKNYTEADFCKYAGEVGEKFYKNLKTIYEDEKTHVDFLKGALGASAIPEPTFDFPVEDADSFLALASVLEGVGVSAYLGAAAVIADKTYVPVAGSILTVEARHSSYIRAALREKPFPTPFDTPLDFNQVYSLAAQFVTGFAPGTPALPFKAFPKLTVSPTPSSHGALFEGAYKAAADAQTVPAGATVYAVFFSGLDTYYKEVAISGNDYIVEQLPEGAAGQVYCVLSTANGNSTKVSDENTVAGVAILEIEEADW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL81</accession>
    <name>A0AAD8XL81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_32848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369522.1">
        <property type="nucleotide sequence ID" value="XM_060502404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL81"/>
    <dbReference type="GeneID" id="85386303"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="200" mass="22064" checksum="7D466FE79015C8EB" modified="2024-05-29" version="1">MLGVGARRVGGGLLLNGEWAALARTGREDVGRGSEMAEAATAETGKVVQFRVLGYLRYVVRYTEYLQKDPRRYDTTRLELEQQALHCYLPLGTTQKYLPSPLLDPRCLTVPTASCLLCGLLPQNPERLDKTGWMGWRGKRSDRVFRMAGERPGRRQRRESPKWTGGLPLGECGCVNEGDDALQVINKSFCASSSSSGALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLX0</accession>
    <name>A0AAD8XLX0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase III RPC4-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_603729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369900.1">
        <property type="nucleotide sequence ID" value="XM_060507241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLX0"/>
    <dbReference type="GeneID" id="85391140"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="32983" checksum="16ECE52A13A0C411" modified="2024-05-29" version="1">MGIARIDKKEEKKTIATSAELEAEEQGKAEESLFVEGEGCFGAIPPMEDETKVWHAAPKAVVQVKAEPGGEPGAMDIAPVDFNAHVKSATPEAEEEKVTPEPKTKKTMADPEVEMITHDMELLLGELGTVTDENSKAPETEVASKDGRLYLFQFPPLLPPLQPATAPKIKPEPDDVVMLDQPGEAVDLTQAEESSKPKVEEADIDLTDINQLVSQAGMMGKLKVRKSGKVELDWGGRTLELSPAAGMNFLTTAVIVEESDEKAKQGVPGGDSIGMGKIMGRFVLAPTWGDEEEWTVDPEDLVVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM07</accession>
    <name>A0AAD8XM07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyketide cyclase/dehydrase and lipid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_603923</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369960.1">
        <property type="nucleotide sequence ID" value="XM_060507252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM07"/>
    <dbReference type="GeneID" id="85391151"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="4">
        <location>
            <begin position="55"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="23170" checksum="A76C9B34780E362C" modified="2024-05-29" version="1">MATARPLLRLPTPLRTSLTSSRALLTTPSRRPFFNLPNLAPSTAPQVLTATRTMPYASTQLYDVISDVDAYQTFVPYCAASRVTAWSAPDPDPANGGRRYPTQADLRVGWGGFEETFTSRLHCVPGKSVEAISGADVEGASPGNGGEGGAVFRSLVTKWQLRPLASGTGTEVDLVIRFQFANPLYAAVSAAVSEKVAGVMIEAFQKRVKAVLGTPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM83</accession>
    <name>A0AAD8XM83_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inner membrane assembly complex subunit 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369943.1">
        <property type="nucleotide sequence ID" value="XM_060513525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM83"/>
    <dbReference type="GeneID" id="85397423"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11931" checksum="D2F34ADA2CF66EEB" modified="2024-05-29" version="1">MAARSSTMILSRALRSQRTTQMPRAASRLYSTSVDGEKRPSIVGTFYKTFTRPVLKVLLMATLTYQIAYWTWTKLEQDEIRGEKSKEIEGLEAKVAELQAGKGTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN30</accession>
    <name>A0AAD8XN30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Beta-ketoacyl synthase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_780442</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370560.1">
        <property type="nucleotide sequence ID" value="XM_060515533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399431"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901336">
        <property type="term" value="P:lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="14"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="12">
        <location>
            <begin position="956"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2483"/>
            <end position="2560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="453"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="956"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1118"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="986"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2568" mass="280354" checksum="5FAF345F10EE1FF0" modified="2024-05-29" version="1">MPFIKEPTCAESTCQPIAIIGIGLRAPGDASDPEKFWQMLLDARSARSEIPKDRYNVDGFYHPDPERLGSIQPRHAHFLKQDFKVFDAPFFSVTPKEAKAMDPTHRMLLEATYEGFENAGLRLEDVSGTQTSCYIGTFTGDFPNLQARDNEGPSIYHATGLSSSLASNRLSWFYNLRGPSMTIDTACSSSLTAFHLACQSIRTGEAEMSVVAGANLMFGPDMSILLGAAKILSPEGKSKMWDANANGFARGEGFGVTILKPLDAALRDGDTVRAVVLASAANEDGRTPGISLPNSEAQQELIRTAYRKAGVDPAETGYVEAHGTGTQAGDPLEARAILKTIGDQPSRKSELYVGSVKTNIGHLEGAAGVAGVIKAALAVERGLIPQNLWFEELNPQIELPVNVKIPTTLTVWPHSGPRRASINSFGFGGANAHVILEDAASYLLRHGLPGRHATVHKPRLPQSPSSNASDGGSETETTRSISSEEPSSKLFVLSANDQDGVKRNVGRMIDYLATKTSGQPLSMADLAFTLFSKRTILPWKSFAIASDINSLYQSLESIPAVVRSSNSSVPGVAFVFTGQGAQYFKMGKGLSVYKAFRDSMLRSETILKSLGCTWTLTEELDRPEAECNLRRTDYSQPACTALQVALVDLAREWGVKPVAVVGHSSGEIGAAYCAGFIDHEAAVKIAWLRGQVSQTVSKNGGMLAVSASAESVSEHLQSLKLGKAIVGCINSPKACTISGDDVAIGELQEILKEAQIPCTRLPMDVAYHSFHMEAARERYEAALAGIPHRSSDIPMFSSVTGKLVTPEQMTPSYWVENLTSPVNFVGAVRSLLHHTQGKVRSHDRFAFAFASAFVELGPHSALRSYLLDTFSTEDRFSDLSYATILRRKFDGVQTALEAMGQLWTKGCDVDINRVNEVTSDTNMLVDLPPYAWNHKLSFWDESYLSREYRLREKPRTDLLGYRIPGTPDPTWRNFLRCNENPWIREHKVQGDILYPGAGIVVMAIEAARQLAEENPTEEVYGYELRDVAIDTALRVPDTDKGIEVMIQLHPRRTGTKAGPSATLNEFAVSSWSEDIKEWTVHARGLVSVTYKSSLSPAMQGELALENKRYAQTFAEAKEICQKPARSFLYDTVETIGMQYGPTFRNMTELFAGPSASYGIISVPDTKAVMPKGFEYPFVVHPATLDSVLHLLFPSISGEDQSISEAVVPFSFDRIFVSAKLSTVPGTKFHGCSTAQKTSYTTWKSSITISEDLSEPMIIMDGLSLASVGEGDTSQAQETRASCFGQTWHVDSDLLEPSQIKELVYKRTLKSKDDDSVLDKLEYVCLVHIHRSLAWLESEEGKAFVPQDGFWKSYVEWMHDTIKQFPPLAANEAEVEAELNAARKRIVLSESGDITVQMVDRIGENLSKIFSRVVEPLQVMTEGDLLYSFYRGAFGTSFNTNVAEYVGLIADKKPGVNILEIGAGTGGTTYHVLERLRNADGTSKAAKYCFTDISPGFLAKAADRFSTDASIMEFTTLNIENEPTEQGFTPESYDLIVCANVLHATKSIQETLSHCKSLLKPGGRLVLSEVTIKRIFSGFIMGPLPGWWLGEDDGRKGGPLLDVEEWNTALNLAGFSGVDVDIRGDREASKEPVSLIISTKPEKQVSGSSQFVVVSTGSELSEKLAQAIKERFVSASHDVSITQWNEVSESQVDGKYCLCLAEWENPILANLTDENWEKLRQVILGSSGTLWITGGAAMECSEPMKSLMIGLSRAIRNENAGIRLATLDLETSSSINFEEAASNVLKVASTHSSGDGFDGEFAARGSTVYIPRVERTLNVDGFLRKFEAKGQPELVSFKGCGRPLKLTIKTPGLLDTFRWEEDETYYQPLPEDWIEVEVKAVGLNFKDVLVALGNLAENKLGVDASGVVTRVGSAVSDFKPGDRVMTASCDTFATYVRFPAKGAIAVPEKMTFEEAASMPLIFLTAYYSLVTAGGLIKDEKILIHAAAGGVGQAAIMIAQRKGAEIFATVGSDEKKQLIMGQYGIPEDHIFSSRDTSFAKAIMRATNGQGVDVVLNSLAGEALRLSWHCLAKFGRFLEIGKADLFANTGLDMKPFLDNKSYIGVNLLDFENNPTPRAVALWEETAKLIHDGSVKPIAPIQLFSMAEVEKAFRHMQAGKHMGKVVVRVDDSDMVPAVPRMPSVDIQEDATYVVAGVGGICKEIGRWLAEKGAKHLVLLSRSAASSEENKAFASELQKTYEANTYAYDCDVGNKAALQEVLEDLKAKGVPAVKGCVTGAMVLRVSQSSQRQRDNFVADNPQQDTLFDKMTADHVRTTVVPKVHGTWNLHELLPRDLDFFVMLSSLAGVMGHRGQGNYGCGNIFQDYFAAYRRSQGLRAMTIDIGYLLSIGFVAEHDEYVDHVKAMGLKVMHKSDLHGLMATALEGSEAHPPQVMCGLPYNEHDDAWYWIQDQRFAGLRKTAAGSGAGGSATVSLREELARCGKADDEAVHLITSALVQRLAKLMMMPEDDVDAGKPLSAYGVDSLVAVEVRNWIAKEVAVEVSVFDIMANIPMRQLAADLAGKSKLLVQEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN53</accession>
    <name>A0AAD8XN53_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine phosphate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_566240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370590.1">
        <property type="nucleotide sequence ID" value="XM_060503837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN53"/>
    <dbReference type="GeneID" id="85387736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39336:SF1">
        <property type="entry name" value="PYRIDOXAMINE PHOSPHATE OXIDASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="30602" checksum="C34BF5CA91B51281" modified="2024-05-29" version="1">MKLYPSLNPDLADWAARQPVFFTASAPTHHPHINVSPKGLSAHFAVLSPNLVAYIDRTGSGCETIAHSYENGRLTLMFMSFGPAPRILRLFCKSRIVEWDHPDFDKWMKRVIPQSDEAGGVGNSNRESYDGARAVVIGEVWEVQTSCGYGVPMVRRELYAPATADELSVFEERPTLDYYWKKRVDNNTVNTYQVETNRTSIDGLPGLKAARRDAGETLWVADLKAEVLRAARETRGVLLGVLIAVLVYFGTGVVGGLVVRWREGREHNWIWPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP37</accession>
    <name>A0AAD8XP37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication factor Cdt1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_599766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371112.1">
        <property type="nucleotide sequence ID" value="XM_060507003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP37"/>
    <dbReference type="GeneID" id="85390902"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26121">
        <property type="entry name" value="HTH_CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Cdt1 C-terminal" evidence="4">
        <location>
            <begin position="401"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="58449" checksum="FD62185AFDAE3711" modified="2024-05-29" version="1">MARAASRRQVKPVATTPATNPISKYGRVSKTQPAPVDDASKKVFFIGLPSSLPVAKTEVKTEIKLESSPERALPPQPAATPSKKRKARSIDEDVSPRDVGIDAPGCESLKRQRVFKNRSKDEPVPIKLEVASTTAINTITTAASTRKSTTSPVADSRRKTRKSDVISQAKTEVRKANQKVKRTKKHNSTKSEIKEEVVKKQLPAELLELLDLQRAILKTVSLQLVHQKNNAPLDISSITPHVARTWGKRRVTVDDIRRCIAIQDTKTPGQEDGSLGSPFIVTDYGRGKLCLEMDLTKNTGRIDENELCQQFEKNLHIMCSQRAMDEMSDLDICFENLSFNDLPKSDITVRHTTMSENPMFAKGQRALTGIKNDILKKQERETQTQATKFSALNPNGTKMTLLDRLRAKEEANANIQLPTGPEMARKRALQRVGDISAVLSMLVSSSNAAGQMVVSFTMTVLQQKLKDSLRVPMPMEEGVDAVRLIAREVAPEWLKVATVGGKEHVVIQTRRKPYEAELAARVNRLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ97</accession>
    <name>A0AAD8XQ97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_1885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371775.1">
        <property type="nucleotide sequence ID" value="XM_060501574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ97"/>
    <dbReference type="GeneID" id="85385473"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="108" mass="12264" checksum="E6F3C91F1958C8AB" modified="2024-05-29" version="1">MAHTSRHALSFLVQFTLPSPRLPRLCFSFLFLVPSVDPEPPIRYTASALELVPSLTDTHSLTRPPVAHRSRFCHCQLPRKESTYSIRTYVLLQGPLQFVGLLDSHLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ99</accession>
    <name>A0AAD8XQ99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MYB DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_597897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371609.1">
        <property type="nucleotide sequence ID" value="XM_060506924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ99"/>
    <dbReference type="GeneID" id="85390823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052450">
        <property type="entry name" value="TRBD-Containing_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46734">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 1 TERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="245"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="568" mass="63164" checksum="EF6B755DC321A3F2" modified="2024-05-29" version="1">MAYIEPRLIHLLNDSTTPQLAHADLPPLRLAFSRPSERPFPLEPETTHREENTKGPSLATTHGAPPQNAGTLDDSFSARDSRKDDEAPIDRGAVNSTAHLQLRLLLGEDRDNADSSFSLSKILDEVPENKDDSANKKRHRNVATKDDFVQLPQPVKKQKPIQPQVMPTMPPIINGLHEPPPDAALFPPIASNDFNEPESNQLKPLRDFAPVPEEKDMEIEVEKPAEADSTTSKNSKSSGGKTRKKAMKPRRKWSEAETNHLLLGVNRHGVGKWTDILADPDFNFNDRTAGDLKDRFRTCCPNELRRTNSEPKITTAAVAPPTTPTEPKARAKTGLLSENILIAQDETAASEQSQMTQADLDAFPKMKRSRAHRKKLEDLAELGIHGPFKKSHRRERRPFTDQDDKQILEGLDKYGPAWTKIQRDPRFSLSGRQPTDLRDRVRNKYPSVYAKIEKGLFQPQDGRGGDTLEPTVSMSISNTLQPNRPPPMEAALNRTNSKEDLPRWPLSVIDNGELPASQQAFDFGETSTATFMGSAGEMDISRLLLDDSQVASSTAIYAPDQTSESTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR28</accession>
    <name>A0AAD8XR28_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_597008</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371919.1">
        <property type="nucleotide sequence ID" value="XM_060506880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR28"/>
    <dbReference type="GeneID" id="85390779"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF5">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="165" mass="18870" checksum="1B8EABD91CB558C4" modified="2024-05-29" version="1">MAAMAAQNPTGGAPEGLPMPSRNPLPLSASQEAQIRDIYHARVRNACAPEIKAFADCALNRTFTVSFVCRTQLRAMNGCMKAHATPQEHDAAREEWFAKRMERQKERERKAVKKAQQEDFIREWWGLPEKDAETRRKEEEKMRLGERVGGYAARDRKSVAAEERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D258</accession>
    <name>A0AAD9D258_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_602289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370356.1">
        <property type="nucleotide sequence ID" value="XM_060507158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D258"/>
    <dbReference type="GeneID" id="85391057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19496">
        <property type="entry name" value="Elp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019519">
        <property type="entry name" value="Elp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15641:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10483">
        <property type="entry name" value="Elong_Iki1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="354" mass="38486" checksum="262899C83F4C4AF7" modified="2024-05-29" version="1">MAPSAENHSRSHSLLLFQKLLNLRDGASPLTLVLDSLEQGAAPVLREFVSRAKIAKAKVILLSFATLKRPRGVDVVVRARGKNLKALRAEILSHYPKMDPTAAKGAPPSQKTVVLLDSLNELATAAPQILLSFLSSIIMPAVSLVAVYHTDVPLVLPRAVSEYEPHPLTVLSHLATSILRLSGLRQEIERQKARNRSLQEPEWGLGEGREGVLVGLKGDVKSEDYQGVVVEMEVRRRSGRAMAEKFVILPQKGQQASSSAASTAAAKGSRIFLLAEHPVFAAPEGSGEAEAGNGEDEEPESTFNLGLTEKQRRDREGIVLPYFDAQTDIGAGEGGRILYEMGREDDFDDEEDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Q3</accession>
    <name>A0AAD9D2Q3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF985 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_746815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371000.1">
        <property type="nucleotide sequence ID" value="XM_060513325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2Q3"/>
    <dbReference type="GeneID" id="85397223"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387:SF3">
        <property type="entry name" value="DUF985 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="RMLC-LIKE JELLY ROLL FOLD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF985" evidence="2">
        <location>
            <begin position="28"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="224" mass="24135" checksum="3679461850FA6269" modified="2024-05-29" version="1">MGSIPLPDLSHLSPSTLPTPHDTPSSAKIVSALSLHRHYEGGFYAETDRAPTSIPSPFPATPASASDEAAPSTNDPDCPPPTTAEQQQRRALSSAIFYYLTASSPIGHFHRNRSRITHSLHRGRGRYVVLHPDGVVENFIVGGNIAAGERLQWTVEGGAYKASFVLPDEDEGASSPSSSEGLLITEVAVPGWEPCDQNFLTREKLVELVGEGKAKGLEWLIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D378</accession>
    <name>A0AAD9D378_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_659865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371449.1">
        <property type="nucleotide sequence ID" value="XM_060511053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D378"/>
    <dbReference type="GeneID" id="85394952"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="593" mass="67117" checksum="B1A04FF5381EC237" modified="2024-05-29" version="1">MQLAMELSSSLTDLSAVSSPDSFRTAFQSPDANSEKPTPTGPASPTRMYSSATLLPRELKEHCQIYLEEHLYNGALGLYNSLLTAGFSRKINTNPKRVPVPPLTHLALLNTLTIHPSHTTRAPGADRLEVCSQTLDYLRNLLAIVGPINAGFRNAFQFHGIHYGRRNRYHDEEDEDLDGDQIGNNKLANEDSIWQRAQDFWAVLGWAFNCSRLHPHRWRFWKTWLKFMIDVLEADIFERKRLDEESLASSQQPQNWTNMRESILVMYIKQKTDSGRGALRMILQAVFADGCTSSLAKFPEVFNKETKGLPSEDKKRKRMTTLDIENDQFGDYFNEELTDDEPSEAGTPGTPRTPRTPARKAGGFVAAPLADSIPLRLRLMELLSEVAYNMPEEFMDHNEYTLDLCRLLKQQPLSFFHQFITDMSSYIQRYGAAFKIDFLAVQLDQLLPSGYEDPKKVIKGEDSGIIINADVLELCYLGHHANTIDPEDNARVALILESLLHTLPAEEIQEARDRLRKAALKGIEARKAKAKGTNRRSATTPSRRGRGKKGPSPRDIYAKETMDLVGERMLLYIDIMGAHEPEGDVDEDENMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4M7</accession>
    <name>A0AAD8U4M7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_595279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000281">
        <property type="protein sequence ID" value="KAK1703485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357298.1">
        <property type="nucleotide sequence ID" value="XM_060506778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4M7"/>
    <dbReference type="GeneID" id="85390677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF17">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="239"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="322"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1703485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="48068" checksum="2DE650DBBF0EF1AB" modified="2024-05-29" version="1">MASGVKGTNGMNVGSNYGQDYLRAVRGITASSFPTEEDRMKALLATYEVLSKLETPWDTYVRIHLNQSAVTAGIKIIKDLNLMMKWKEQGFVPMTSIQLAGLVGSCDPQLLHRFLRSLAANGLMEQVPIEKFKPNQFCMELAKPDFHTLTNFYYVTGHRAYGTLPDHLAEKGYKDPSDPADTILRKSTGHNGDLWSFLSENPKIGEMFNIVQKASTNKEPPWMDMYPHRNLVDGSDPSLPLLVDIGGGIGHDLSRFYKAYPNEGSRLYLEDLQSVISDAKNKALLPDTVKQVEYSFFEPQPVKRSLYESLCTNSALTCDTDARAYYMHHIIHDWPDHSALKILEMQKGAMKPGYSRLLIHDQVLDDGKSQLNTTAFDIAMMVYLSGKERTEKQWLALLDSAGLRVIKFWRKPPDYFSVIEVEIPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7H7</accession>
    <name>A0AAD8U7H7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_640382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000169">
        <property type="protein sequence ID" value="KAK1710578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358857.1">
        <property type="nucleotide sequence ID" value="XM_060509484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7H7"/>
    <dbReference type="GeneID" id="85393383"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1710578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="54" mass="6115" checksum="02DCDFD47FF9734B" modified="2024-05-29" version="1" fragment="single">MTADVLDYEHLRGRSYHSDIFSSTYWAPNDELQSEAMGLWSGQSKTCDPGHHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U929</accession>
    <name>A0AAD8U929_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_684369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358318.1">
        <property type="nucleotide sequence ID" value="XM_060511240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U929"/>
    <dbReference type="GeneID" id="85395139"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="139" mass="13878" checksum="CEC5167C720A32F1" modified="2024-05-29" version="1" fragment="single">MMGLEGALAQARTDVAPTSPIGISDGIALQNAADTLTKSVKIMVMSAMLQRQTLDQINMTPMLLQSFMNQNMLSAALGQVVLSKLPAEGLQSAMAAFAGAGGSVGMGIVSLANPPLAMPPGMGPPMGGAPPAAMPATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9R4</accession>
    <name>A0AAD8U9R4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_591723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000177">
        <property type="protein sequence ID" value="KAK1709982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358678.1">
        <property type="nucleotide sequence ID" value="XM_060506466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9R4"/>
    <dbReference type="GeneID" id="85390365"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF10">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="30622" checksum="74B0EED940F70804" modified="2024-05-29" version="1">MAEFLIEDKDLISLKGKVAIVTGGSSGIGLAAVNTLLSQGASVVNADIQPPAEQPENSYTFVKTDVTIWADQIALFKKTKEVHGRIDHVFANAGLGPRANYLSTEVDENGDLKEPTHQLLDVSLTGVMHTATIAIYYMRQQAEGGSIVINGSTTGLQRLRAVDYSTAKHAVLGFGRGLVPLIASANLPIRVNTLAPTWADSSVLPDLKGLMAKIGVEIQTAEAVARGAAYLMADTTRNGNVIHVQLGKYKEIDEAVLLPAFESIKGPDYPGEDEVLRRLQELMMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA26</accession>
    <name>A0AAD8UA26_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_797912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000236">
        <property type="protein sequence ID" value="KAK1705790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357694.1">
        <property type="nucleotide sequence ID" value="XM_060515909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA26"/>
    <dbReference type="GeneID" id="85399807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF8">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="343" mass="36808" checksum="53D62A51EFA1E4DC" modified="2024-05-29" version="1">MDATIEWFGATTFRVKANGLVIFLDTWLERPGVLPKVLAIDDVDEADYIFISHAHFDHLPGADKIAIKTGAHVIANGEAINVLRSAGVPEDQLIPVSGGERIPIFPFKCRQAAARGEVDIAPGPPGAPPAPDARLAAASVHVWPSLHCLMPGGSHADVPAIMDTGKEYIGGASQYTCTLDITFGMKYGLLKIGDHVPRNAMDSGMRSFVDYVSGPARECMSHFDGGQLMYNFLFGEGKTLLWNGHLGGYDGILKTVQPQPDVLIQAIAGRANLNGRPFDGSAAQFAVQVSKLLGEPNKVIWCLHDEAPIKPWTVDVSPATQAVEKETGSKVTTLQLGTLDMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAH2</accession>
    <name>A0AAD8UAH2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CSN8/PSMD8/EIF3K domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_234939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000286">
        <property type="protein sequence ID" value="KAK1703244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357261.1">
        <property type="nucleotide sequence ID" value="XM_060501835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAH2"/>
    <dbReference type="GeneID" id="85385734"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006746">
        <property type="entry name" value="26S_Psome_Rpn12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12387:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="3">
        <location>
            <begin position="136"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1703244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="24693" checksum="17CD96F471680265" modified="2024-05-29" version="1">MFHDHCRHQSPDNRTTTNPMHPAAHIHHNHQKWRAATSNRSLPSSRPRAPRSLHRILRPPLQSKTPPPAQHPHPFEPQNFPPSSSPSPARPKSWAPSPPSAQRIQTPSPATSSSSSLFTSFPPTSSRPMSPSATSAVEGDKYLGYPIRLERWLMEGSYDRVWNALKSREGPSKEYGVFSEILTFQIRSEIASSSERAYSSLPISPAKSLLFLDSEGDVISFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAM9</accession>
    <name>A0AAD8UAM9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Male sterility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_761402</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360627.1">
        <property type="nucleotide sequence ID" value="XM_060515184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAM9"/>
    <dbReference type="GeneID" id="85399082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="611"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1093" mass="121204" checksum="07F0F6EB13630A5F" modified="2024-05-29" version="1">MAPIAMSDLKSPSSIAAVDSTVFPASDADERLKKLWQLHGHPHSSRFCDPNLTSVAALVEHNAATQPVKPAFIHPVGDSFEVLDWAQLNQYCLTASGFYSKQFRGGIATANEIGQQPTVALLGVGNSISYLITQFALNRLHLRVLLLSNKNSPATRDHLLKVCNVVTIITDEASEASLHGESPCQLPVTKLISLDELRGNGLEVYEEPGMGFETGDEWNVQSMIIHSSGSTGVPKPIIHTNRSLCQIARMYRLLPEFFIENWYLCFPLFHVAGLSIALSGLPTGLPTSLPPTQWPPAPSSILSAWKSLASLGYPPDCLHCAPSVIEDLYEYITLTTKDYTPLTDLKVLQPGGAPLSPSLLSKLQKIGVNVKTTYGTTETGPPLRTIPHTRDNPDVYRFRNLYPESEYVRMEPIADNLFECVVHRGFPLAAELWLEETAPNPYRTGDLFNEDPPGSGYFVLQGRRDDILVHSNGEKTHAAALAMALEEDKTGIVAKTAVFGTGKPFPSVVVEINWSEVEKRSISEADLPEEVWKVVGVCNNNSPTYSRIPRETVLILQEGKTLPVTPKGNVRRTIAWELYGDRVEELYNSFLGTKLDADTEAASVPSRDPDISDLQTIQTVVAEVFRVPVDGLTEDQNWYELGLDSLRAVDIRSRLVQIFGAFPLMFIFEYPTAKKLLEFLQLFKSGLNSNAPAASNHYESMRSTIHRMNIEIDNWQVTQAQQEDSISDEQVIYLTGASGALGNALLEVLVQVPTVRKIYCAVRGADPQARVLGSIKERGYPTSIYQSEKILPVSYDMKDGKLGVDEQMYQRLMNEVTDVMHNAWKLDFNQPIQQFEDDCLRGTMHLMSFCLKGLKKTFTFMSSVAAAMGSPAGTKVPEIPLSPDPANALPTGYAQSKFIIEQVTQHYASTHNVPVRILRVGQLCGHSRLGAWNNTEMWPTMMMVGLDLLNAMPTLQTNVDWLPIDFCAEAISKALIHNTPETSYAVYNLINPSAISWEQLVSMLEEAYGQNFQRVEMKEWVSRLEATAESQGLGVRELPALKLLGFFQSMAEGNGNGEGVGFDAGSVEKGRRIEVDMLKRWLEVWRQTGHLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCV2</accession>
    <name>A0AAD8UCV2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CheY-like superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_634934</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360508.1">
        <property type="nucleotide sequence ID" value="XM_060509135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCV2"/>
    <dbReference type="GeneID" id="85393034"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF3">
        <property type="entry name" value="HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="47"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="183" mass="20032" checksum="C7FB5FAE9DC3507D" modified="2024-05-29" version="1">MAFPSEEPLPKNATRPLEELSTEQLGLSSPPQTDSIPTAATATPSINILIAEHNQVVRKFIARQMDGLGHNCVYDFACNGQEAFEAYKKGHQLYRCILMQPSMPVIDGLHATRLIRAFETENGLKPCYIVVMAAGISMGLDMDRTRSLGFDALIQKPFKTEGLERLLVELGLVSKGPVGSSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD63</accession>
    <name>A0AAD8UD63_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_765153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359239.1">
        <property type="nucleotide sequence ID" value="XM_060515245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD63"/>
    <dbReference type="GeneID" id="85399143"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF13">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="61535" checksum="34D97D66FAEB8A1D" modified="2024-05-29" version="1" fragment="single">PEEPPRSFFNTTPTPLLRRVSNRLATGLKDLTDRGPPSSPSFRPPQNESSSSLVPIIRSLSRRGGGGGRNRPIPHLPYRIPDPDPMAPSGGGSSTNPGAVKHIRDKFVRWTARPDGEYDARWKGAFIPTGEHVSKMLEWYTQRDVYEFPIHHCGATNAFYFVEFEPLSRPVGQGKSSPLPRQVILKLSLPVCPHEKLEAEVAAMVFARQVSPAVVPQILVFDSIGRNPLGLEWMIMEVRTGFPLLSAFEENYILAAHDLNMAKQDAGLDGFGDISPETMPSLSDEDTKAIAREVQLFLSELQSSLPTVPKNQVSIGSLRIDWSKKEFFTGPIVHPHFYSRDRYWQVRNNGPFRYIEDYIDAYTSVWEPEYRSHPEIKLREIVRAMTSRVRFSVPNPILVESTGGSVDGWPVSLVHPDPHPGYILFNGNRKLASIMGWEDAVLIPAPLRNLPVALDWAMQLHGVTDAIDPMQVNVLEALPILKERVLLTLQEWAKRHVSESLEPVMNFQGGIDASFQALKIACEELMRQRSIDWIERVHSQLVGRSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD73</accession>
    <name>A0AAD8UD73_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_634470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360718.1">
        <property type="nucleotide sequence ID" value="XM_060509099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD73"/>
    <dbReference type="GeneID" id="85392998"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="28"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32388" checksum="675BAB3A19B83302" modified="2024-05-29" version="1">MASPSTVELSDGAKVQVRLLGDSDGTKPLIIVLHGAPGLSDHREPVSSFGFLASDFRVLVYDARGSGESDLRPPYTDERWVADVDELRSWAGADKFVLAGGSYGGFVALRYALSHPDRLLALILRDTWACGLRGAFNFIKTILTSDRIKPDPDRQVRLNSGNIQDNEDFAAAFAEIVEIYKPKDDSTSVGSKNATFEGNDAHEHLHYETHNFAFSYNLPRLDVRSQLKDITAPTLVATGRHDIVVPVEYGEEISRGIPNSELAIFEKSGHSPPTDEPEAFRETVSRFLSRWVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDW7</accession>
    <name>A0AAD8UDW7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutathione S-transferase UstS-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_629164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362427.1">
        <property type="nucleotide sequence ID" value="XM_060508750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDW7"/>
    <dbReference type="GeneID" id="85392649"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="2">
        <location>
            <begin position="149"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="300" mass="33493" checksum="B21C75886A9D40BB" modified="2024-05-29" version="1">MNATSTQSDTQHSTSVSPNMDTSDKPTITFYDIILDPKAYPMAPNPWKTRFALNFAKVPYHTTWVPLNAVAKTRNSLQLPANRKHDDGSDFPTLPIIRDPLASSSSSGEKKEEIVGDSFDIALHLQRTYLANKKDQLFQDGHNGSSTLALHRVFNAFVDQVFSQYGAPLGGFYMPLDPRTAEADRQSFLDRFPGKKWEDLEIPPGSDVRKTMLADFETNLEAKLGPCFPAGGAGPFMDGRESPVYADFIVGGWLQFMRGCLPEWEALRNEWSGGKWGRLFDALQEWTDVDGREGVVPAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDZ3</accession>
    <name>A0AAD8UDZ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_585985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361183.1">
        <property type="nucleotide sequence ID" value="XM_060505900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDZ3"/>
    <dbReference type="GeneID" id="85389799"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1718183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="135" mass="14526" checksum="DE44D34489D39902" modified="2024-05-29" version="1">MQISTLSVAAAVFQSFVKAAYPPNSLGTFAYSHGNQLVTENPSTQTTAQELVELCNSSGAIQGIATCTAICVANTYVFGLICRKPFSFTDDFTNRTYANLEPACVGDIIGILLEPDVTAVVYRNTKRPSRHLVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE11</accession>
    <name>A0AAD8UE11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar import and degradation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_18705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361213.1">
        <property type="nucleotide sequence ID" value="XM_060501563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE11"/>
    <dbReference type="GeneID" id="85385462"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="379" mass="42606" checksum="6D9F527360F73A99" modified="2024-05-29" version="1">MPTPSSNPPPDPHSPRSHSFSTCPEDSSSRSPQRSWRPPTNASQAPPEMDPHHDDPMDDDSSLAPVSAPMSQAEGMSTEVILDDEPTSAVSSSRSTTMSPRPQSGDTANSSPAADMESFKHAESDEEAHTAGNRLRTSRPDGARRHDPRLSPTSVQHEDNKGMELDVDDVWEEELMAPSMGSDFSNMRIIPSTASSYLRPGSKFHGTQQSERQVYDVQVEIKHVDLRESFLCGYLRIQGLTEDHPTLTTYFEGEIIGTKYSFITGHESWGATDKIDLSHWGKFNAFRPLQKQARKGPVVIRDVAQRENIFMRWKEHFLVPDHRVRTISGASFEGFYYICFNQVKGEVSGIYFHSKSEKFQQLELKHVEDRGCFGAMEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEK9</accession>
    <name>A0AAD8UEK9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_588062</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360299.1">
        <property type="nucleotide sequence ID" value="XM_060506095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEK9"/>
    <dbReference type="GeneID" id="85389994"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000103">
        <property type="entry name" value="NADPH oxidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000004">
        <property type="entry name" value="NADPH oxidase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="277"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1715500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="65637" checksum="2F4F7238C62A9BFF" modified="2024-05-29" version="1">MDYYYAGSEKPSERSRWTPLTRMLLSGEMTQEKQKDLTMRERFDRWMINEGYRRVFVFVFLVLHGLVFAFASVNFALKDNLQIARDTFGPTFIIARSAALVLHVDVALVLFPVCRTLISLARQTPLNGIIQFDKNITFHITTAWSIVFFSWVHTIAHWNNFAQIAAKNNLGIYGWLLANFVSGPGWTGYVMLIALMGMVFTSVEKPRRANYERFWYTHHMFIVFFFFWSIHGAFCMIQPDFAPFCTSIGTSAIGVFWQYWMYGGFVYLAERVAREVRGRHKTYVSKVIQHPSNVCEIQIKKEHTKTRAGQYIFFCCPAVSLWQYHPFTLTSAPEEDYISIHMRVVGDFTRAVSMALGCEWDKKKDDASKVVGVNSDSSEVDPALRRVLPRVYIDGPFGSASEDVFKYEISVLCGAGIGVTPFASILKSIWYRMNYPQQKTRLSKVYFFWICRDFGSFEWFRSLLLAIEAQDVDNRIEIHTYLTAKIKADDATNIMINDANADKDTITGLRSPTNFGRPNWDMIFRGIRKLHSPAEAGVFFCGPKGLGSTLHIFCNKYSEPGFSFVWGKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEX9</accession>
    <name>A0AAD8UEX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein HRI1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_744130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360291.1">
        <property type="nucleotide sequence ID" value="XM_060513153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEX9"/>
    <dbReference type="GeneID" id="85397051"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd11693">
        <property type="entry name" value="HRI1_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11692">
        <property type="entry name" value="HRI1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.320">
        <property type="entry name" value="Protein HRI1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031818">
        <property type="entry name" value="Hri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038744">
        <property type="entry name" value="Hri1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043047">
        <property type="entry name" value="Hri1_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16815">
        <property type="entry name" value="HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1715492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="27399" checksum="AC4130D67093DDDA" modified="2024-05-29" version="1">MGSISFREHIRWIPDEASEPTSTIVLTSPQRRFVDLRILKQTPTVDGVQDTHGIERLEWGIAGTSSSSTRTDDQGAEVRHSRWEHWIDSRTTDPENAADEGDMYEQPDGLTLEKGRMVNPATGTETDYEELWRDVEPVTVPPVGAAAEGEAQKGVECVVLKHEDETSGARGMVVWLGRFCQGISRVGEEVAAERWEWREGEGWRRVVRIGNRALPCEVLLMTGAALSVGTHVVHEEVVWDVLESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC1</accession>
    <name>A0AAD8UFC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bladder cancer-related protein BC10-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_754028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362941.1">
        <property type="nucleotide sequence ID" value="XM_060514426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC1"/>
    <dbReference type="GeneID" id="85398324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009598">
        <property type="entry name" value="BCALP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13259">
        <property type="entry name" value="BLADDER CANCER 10 KD PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13259:SF1">
        <property type="entry name" value="BLADDER CANCER-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06726">
        <property type="entry name" value="BC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01396">
        <property type="entry name" value="BC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1722886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16496" checksum="4EB1657649527356" modified="2024-05-29" version="1">MFCLRSWLPLLFIPTNASPAFIFLFFICTYFLNRPCVYCSFLLVILFLTSCNWSDRCFFDFSSNWFQPRPPTSLPLPELDPNTSFNASVVEVINSTASALAGAAAEELARQRQEWTGLGIEWLRSLLGRREWRVDCLDINIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFJ2</accession>
    <name>A0AAD8UFJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor IIIC 90kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_581820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1722991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363046.1">
        <property type="nucleotide sequence ID" value="XM_060505494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFJ2"/>
    <dbReference type="GeneID" id="85389393"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024761">
        <property type="entry name" value="TFIIIC_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024764">
        <property type="entry name" value="TFIIIC_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12657">
        <property type="entry name" value="TFIIIC_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12660">
        <property type="entry name" value="zf-TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="51"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC putative zinc-finger" evidence="3">
        <location>
            <begin position="746"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="87973" checksum="8422BFAB116CBA33" modified="2024-05-29" version="1">MDDITAFSRTLTLNPPNHNHTLTPLDDDQIPPLKTLTLKSRPLASHALTFSCDAELAVAADDSIHVFLPEFPTPEEPNNKQEPSKDGNEDTKTAAPAADEDPAGVAAAALAAAAADAKDGEKLYRQQFYTFQLRIPTSRKPDPRMNAALFAARGLPVPSYDDDWAAGEAAAGGPGEAAVPDPSSAFEGVGSGTVTGYGASLNQVVAIEWSPGNLGRNLRAVLTVMLTNGALLVIGEGSGSGGGSTSHGPVDLGARMRNFRDWRILWGVGANLPLPDPDAEEGGDEGAHLPRDKVRSFAWARMVGTGQALLAYATDLEEVVVLSAQYYLPNETDDASDAGSYVWEVEEVARFDGRGPHPSLGVLDPDYIPYTSAFSLKWSPWLHSGDTRTAILSYCARNYVGFRRITIPADWERGAAVEMAVEEADVTGICTNLLSDAFVEWEDVVWDRDDVKICRGVIASPFKASPFQVALNGPEGTAKEPHGTGVCKTTFPEDTTSMDATNPITSLIIHPPNLSKQTKAPGYSLIRLSATATNDNWFQQSTADGAASPSPDSLPKWAETISSTVKLSVPVTMLGRGGGAGAGAVGGDGESVASGDDSDSEDDDDDFDLPEDAGEQIHPHRVRMWGMTMTPAGGMSAVLVSQHSTQKPEKTVKTKVMFGGRVGNGPAAVTTAAGDGDEMDVDGGDDGGRASRLQYWEKQSTEAKMWDWMYAGGPAVPGTLWAGTGDEARAGDDNSLKKRFEEVKGKQTCVFCHASLVDEGKESICEKGHIFATCASTGLAILAPGISRACAVCGLRCLVAKEVVKIAQEHMGPDAKVDASEEACGGCGGKFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG07</accession>
    <name>A0AAD8UG07_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetraspanin Tsp3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_753734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000068">
        <property type="protein sequence ID" value="KAK1723231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363286.1">
        <property type="nucleotide sequence ID" value="XM_060514386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG07"/>
    <dbReference type="GeneID" id="85398284"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="32166" checksum="BDE59B56F854130F" modified="2024-05-29" version="1">MGVNPGVVFLLICIGLLTTAIVVHVTSTNLALPISPFLSLLPILLPILGTINAFYYPRLLFNASSSLARTEQLFPTIIQTLQGILTTAVAVILLQTALPGDGLNCALSTSWQRMFVAKDESTIRRIQDSFNCCGLNSIKDRGWPFGANARCAEITGRDTACIGPWRDATVRNSSIDLGIVITVGVLQVLTLLFMQSASNWRHAWWAQPWSHLSERPIEERQRRPLLTATISTHSAHDSGEESEDIVRYSDLNPHYGTTGEGQRGRIRNGSSRIEPSSLRNVENAENEWRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG90</accession>
    <name>A0AAD8UG90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_733759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360966.1">
        <property type="nucleotide sequence ID" value="XM_060512924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG90"/>
    <dbReference type="GeneID" id="85396822"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="360"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="45229" checksum="FF45A2B2E74C8004" modified="2024-05-29" version="1">MASIPGNNDDKPAPLFGAVGAPNPKRAVDWVPSLGDRNLADESETDACNQLLILITGGQNFMLEGMNLKVAWPNMVRQLYPWFQSNGWIWMGTSAIKYWAMRELYKKNNIQLEKPVHTLGFTPPPNVIEEIDEGYSNYLKANHPIYYEHNKHRIPKKKVSVASPAVGAAESSRKDVQVEDIEPQNDGHNKPEVPTNASNMLSPLQAVTINSGTTTPTPTPTPSAPVVTMPPSKFESMVLAARKDLKKYWEDCGGDKILLDKDGYPFEVRVPDRSSPDVAKYIYRNAGQMAKVNKILDPRLRLCWIDHDEATFLVIVKNDMRGDYDDIISYPESWNALRAWSQSVADGQVATLGEFVRSYNDKARVEAMQAYKEIAEKEKLAEALEEHDATMASSRRQAEHEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGC8</accession>
    <name>A0AAD8UGC8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein SSH4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein ssh4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_720468</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Components of the endosome-vacuole trafficking pathway that regulates nutrient transport. May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSH4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363822.1">
        <property type="nucleotide sequence ID" value="XM_060512277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGC8"/>
    <dbReference type="GeneID" id="85396175"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="12">
        <location>
            <begin position="80"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="52643" checksum="C08BE4516E805B3F" modified="2024-05-29" version="1">MAPSAPSSALNGVVIGLLSSFGSAILIALIFLVIYFFRYTASGRIFLDRIGRPGEYDDEQAFAREEAEALESMDDMQRTEYLRAKAFIQANPPESVQTDISLSQYLAIQEKGVSAWEFEPELEIANCFVEGRTEIEFFDSECTVMSNLPVPKQNEVYYWEAKIYDKPENTLLSIGMATKPYPLFRLPAYLSAGQRRCNQPFAATPYGPQFVQGDVIGVGYRPRTGTIFFTRNGKKLEDAVHGVKSQNFFPAIGANGPCIVHVNFGQAGFVFIEANVKKWGLAPMTGSLAPPPPYGSEQGDILLEAGRKDGYTSASGGGGQQQRGHSQSQSYSQSGLGPQHGRTRSGNFRVLPPRSPGPVRSPTDISLTHFVSDDEGGEPSSSINRGHEGQSVVGLGLQDALNPPPEYTSPDHSEAGSRRNSTDSENTPLIRVLNRSRGASAAAAAGPSHPPIPSYTDAVRAGAGREGNSTPRSSNRRGNRSRSQSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGE8</accession>
    <name>A0AAD8UGE8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_753173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363852.1">
        <property type="nucleotide sequence ID" value="XM_060514317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGE8"/>
    <dbReference type="GeneID" id="85398215"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="737" mass="80149" checksum="74825A140DF8657D" modified="2024-05-29" version="1">MTDSGSASSGSGRGGVCLAEHSPQFAATREPFRTTPSSSSDSTVRNARSPSDVFAADLSNQNSQLNHKNYQLPQPPKFQPTNLTSAKSQDQGSNQRPSRTIIQNPAHFSTGKASFPSERTAFATPTGRSAVQPNAFGHRSGPLPSTTSIRDFEITPNAKTPGHHTPGSLNNDTRRIQQHPAPVENKTKLKPTSELTKTNKLIAKMATHCQIDGPLAGPLRESRRSELARDHPAWIPARQVQAGIMTTQQAIRRTPGIPANIANDLCDGLQVYSQKVNDILRQAVNEVADIKIDLEYNDKVLCSNKLEASIISEEREQLKRDVAEIHRKYEELEDRLARYHVEQENHKNTVLEFLARLDPRNDEENDDKAQIVAELLQTLKDFMNRPSSRWMHGERENSSKAIAILSTESIAALEKENQPQSAERLQQSQDARRAPGSESHEMVPTLDNALQPFYHQQYMPGFPPAQNGPSTSFPGMYGPVRRSGDNHTVSSTGWTRASSGAPTQYTGSYPQTRDIQSGFNGGYQHPNGFAGPSNHRGQFNMPSRPGTAMGHRGSFRPNAPVFHPGMYGNADNSGSHNDASYNMSYGPGSNAGSRHNFNGGSTPFRSPIPRSAGHYGNFEGPGDGFSRPSPLVPSGRQSSHGSQYGMGSNHMGYNNDYSMVPQRTRSHGPNSSGNSHHTANIRQQGAFSPGPFGQGGNGPSHAVTSPLAPGNGFSEDEGGDNERYARALEGVWGLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGN0</accession>
    <name>A0AAD8UGN0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Casein kinase II subunit alpha</fullName>
            <shortName evidence="10">CK II alpha</shortName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_795977</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360320.1">
        <property type="nucleotide sequence ID" value="XM_060515856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGN0"/>
    <dbReference type="GeneID" id="85399754"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006356">
        <property type="term" value="P:regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="32"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1715521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="341" mass="39943" checksum="DEB9FC3329E3AF38" modified="2024-05-29" version="1">MARVYADVNQNMPRSYWDYDSVNISWGVLENYEVVRKIGRGKYSEVFEGINVVNYQKCVIKVLKPVKKKKIKREIKILQNLAGGPNVVALLDVVRDSQSKTPSLIFEHVNNTDFRSLYPKFNDLDVRYYINELLKALDFCHSKGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHQGTEYNVRVASRYFKGPELLVDFQEYDYSLDMWSLGAMFASMIFRKEPFFHGNSNSDQLVKIAKVLGTDDLFDYLDKYEIELDAQYDDILGRFQKKPWHSFVTAENQRFVSNEAIDFLDKLLRYDHQERLTAKEAQAHPYFNPVRDPEVFKQHLANQTASGVSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHB4</accession>
    <name>A0AAD8UHB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alpha-aminoadipate reductase</fullName>
            <ecNumber evidence="6">1.2.1.31</ecNumber>
            <ecNumber evidence="5">1.2.1.95</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">L-aminoadipate-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_720917</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) = L-2-aminoadipate + ATP + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46936"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.2.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12308"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>(S)-2-amino-6-oxohexanoate + NADP(+) + H2O = L-2-aminoadipate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12304"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58672"/>
            <dbReference type="EC" id="1.2.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.31" evidence="6"/>
    <dbReference type="EC" id="1.2.1.95" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363223.1">
        <property type="nucleotide sequence ID" value="XM_060512322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHB4"/>
    <dbReference type="GeneID" id="85396220"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004043">
        <property type="term" value="F:L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000787">
        <property type="entry name" value="L-2-aminoadipate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014397">
        <property type="entry name" value="Lys2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03443">
        <property type="entry name" value="alpha_am_amid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF1">
        <property type="entry name" value="L-2-AMINOADIPATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001617">
        <property type="entry name" value="Alpha-AR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="19">
        <location>
            <begin position="619"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1723168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1159" mass="127163" checksum="4FE76F6E7627F4A5" modified="2024-05-29" version="1">MVDLPDPTIDLDWSGYVGAIHEIFHKNAQSHPDRPCVTETKSQTTPTRTFTYRQISEASNTIANHLHDAGITNGDVVMIFAHRSVELVCAFMGTLAAGATVTVLDPLYPPQRQQIYLEVSQPKALISIGKAVDENGPLAPVVQKYIDEELSLKTQLPNLRLSDAGVLSSGEQDTEDLFASVRAKASSLPDVIVGPDSNPTLSYTSGSEGKPKAVLGRHYGLTRYFPWMAERFNLSSESVFACLSGIAHDPIQRDIMTPLFLGAQLLIPAKEDIQHEKLSEWMNAWSPTVTHLTPAMGQILVGGATAKFPSLKHVFFVGDILTTRDCKVLRKLGPSCAIVNMYGTTETSRAVSYFEIPSAEADPTALDSLGDVVPAGWGMHNVQVLVVSRDDHNKMCGVGEVGELYIRAAGLAEGYLGEPEKNKEKFIENWFVDNAKWVEADKASANGEPWRQYYKGPRDRLYRTGDLGQYLPSGAVQIRGFRIELNEIDANLGGSPLIRDCKTLVRRDRNEEPNLVSYIVPEIAEWKRWLEAQNQEDVEDEGVEMGSSVVYLKRFRRIQAEVRDHLKARLPVYAVPSTYIVLQKLPLNPNGKVDTPALPFPDTTEMMEDASEEDLKSWEALSETEKTVAAQWATLIKGLNEKTIKSESDFFDCGGHSLLAQQLLLNIRKNLGVDITIGVLYANPTLSALSTQIDRLKSGQAPMVDKAAEAVYAKSLDELVNTLDAKYQSADPAALSPSAGATFFLTGATGFLGAYLVQDILSRQNTKLLVHIRGVKDTAAAKERLTRSLKGYALWQDSWADRIDCVLGDLSKPRLGLDDASWKQVADKADVIVHNAAYVHWIARYEQMMRSNVLSTIDAMKLCNEGKPKILSFVSSTSTLDTEHYVNLSDKETATGRGAVLEEDDLQGSRSGLGTGYGQTKWVSEQLVREAGKRGLRGAVIRPGYILGSRHGGVSNTDDFLIRLCKGCVQLKARPRIVNSVNAVPVDHVARVVIAAGLNPLPGVNVVHVTAHPRLRMNEFLSTLSYYGYDVPEVDYEEWKTQLEEFVSAGAVEKDQEQSALMPLFHMATSDLPSTTRAPELDDRNAVAVLKADAERWTGVDDSAGEGITREDIGRYLRFLAETKFMPLPTGRGRELPPIPAGVAEAQAQFGVGGRGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI26</accession>
    <name>A0AAD8UI26_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="5">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_719774</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364737.1">
        <property type="nucleotide sequence ID" value="XM_060512210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI26"/>
    <dbReference type="GeneID" id="85396108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000014">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009725">
        <property type="entry name" value="PRK13252.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="504" mass="53906" checksum="CF4819F4DCF38055" modified="2024-05-29" version="1">MAPQEQKQEADRHTFYAGKPQPDTESPGTFQSIDPATAKPVCTIHTSSAASINAAVDAAKTAFPSWSATPPIERSRILLRAVALLRERNDELAKIETLDTGKAFSETQYVDVVTGADVLEYYANLVASGGLNGESFRLRPSAWSYTTKEPLGVCAGIGAWNYPIQIALWKSAPCLAAGNCMIYKPSEFTPLHAEYLASVYRDAGVPDGVFNVVYGAGDVGAQLTTHPNIAKVSFTGQVSTGKKVAGAAAGGMKYVTMELGGKSPVIVLPDCDIEQAVDGAMLANFYSSGQVCTNGTRVFIPKAIKAEFEKLVLEKIQYVRAGDLFDPATNFGPLNSRTHLEKVQAYVRKGVMEDKATLLCGGATQPKGLPSAYKSGFWIQPTVFTDCTDDMAIVKEEIFGPVMSILTYDTVDEAVQRANTTDVGLAAGVFGRDVDQCHSVIQKLEAGITWVNTWGESPAEMAVGGWKSSGVGVENGRKGLEAWVRNKSTLVEMGGSVPTVFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI67</accession>
    <name>A0AAD8UI67_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_630257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362159.1">
        <property type="nucleotide sequence ID" value="XM_060508811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI67"/>
    <dbReference type="GeneID" id="85392710"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF162">
        <property type="entry name" value="SATRATOXIN BIOSYNTHESIS SC1 CLUSTER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="12"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1721363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="39826" checksum="E4AB87256CA6AC6C" modified="2024-05-29" version="1">MWGAAFGMTVFRGTFQWILQRRLFADDYFIIAGLVTLTALTAVITCMLPQFYLAGEYTKAAAKDPLAPVPLGPEEFIARTIASLKLMFCQMLLFWTTLWAAKFSILFFVRRLVTGLPKYIRAWWMCFGAVLVLYLACMLSNFLTCTPLTKYWSATGCSAPEDLVRADASIKFATSADVAADILIMILPLNLLRKLSTSPSHKFGLAILFSLGGIIVAFAIARLAQVTKATGDAAKDPTTIANGPVLLSMWSHIESSVSIIVATLPAFRFLLSKNRNATRKTTAKYVGPTIGGSGGMSLRSRKWQKGGVRLEGESDGRGSSAQDSETELRPVRGIQKDFEYKVEQLSADPSAGETRRKTQELFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJL6</accession>
    <name>A0AAD8UJL6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_624321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364037.1">
        <property type="nucleotide sequence ID" value="XM_060508434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJL6"/>
    <dbReference type="GeneID" id="85392333"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF6">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="2">
        <location>
            <begin position="116"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="41665" checksum="6ECD854A7ADBF0F6" modified="2024-05-29" version="1">MANNTSTPADPMAAASNAMMASIQDYIRTAVTTEVANLPNATQPAQLAALQSRLETANQENSELKEKIKQIESKKSTRHSHKRERDTVKAAFSSYLGFPLPDSKLSRHSHSKSSKFPQFQKFPVEIRMKIWKLALPAGRIFDLSNVDAHFSRVLRAPIAANNGAPNPALVLRQASGLTEMSVTAHKTPKLRLACKEANKAFLEAGGFEFGLFGGPYKGLWYNYSEDIVFVREEPRTWTNLDMSRIVRVAFPHNRFMCKADATAKMDTILDHFTSCKEVILMQTMEWDIRSCLASPRLPAKLFPLQEADPISTHDYPKELSDNVGSVATWGDVKRIVVHIWDDHVVNVKHLSPGRVPKFSGIEVLKARPSYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK06</accession>
    <name>A0AAD8UK06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_719235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365386.1">
        <property type="nucleotide sequence ID" value="XM_060512157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK06"/>
    <dbReference type="GeneID" id="85396055"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018983">
        <property type="entry name" value="U3_snoRNA-assocProt_15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924:SF26">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924">
        <property type="entry name" value="UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09384">
        <property type="entry name" value="UTP15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="120"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="163"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="253"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 15 C-terminal" evidence="7">
        <location>
            <begin position="385"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="58022" checksum="E799CE8A32152721" modified="2024-05-29" version="1">MAATVGPLPQVKLPSGPSPVTAEQRYWKSFKNQLQIPSPTSYPITHISSTSSDGLFAVTTGTRVQLYSSRTRKLEKTITRFADVARSGSLRRDGRVLVAAEDTGRMQVFDTHSRSILKTWTKHRQPVWATRFSGSQPTTLLSASDDKTVRLWDLTANDPLNTFVGHSDYVRCAEFFPATSPSGAGNVIVSGSYDSTVKIWDPRIGSNAAVMTFKHAAPVESVLPLSSGTTLLAASGPQVSVLDLVAARPIHQIANHQKTVTSLSLASNGTRLVTGGLDGHVKVFETTGWNVVSSTKYPSPILSLRVLPVSDALDSADRHLVVGMQSGVLSIRTRLTGPEATRQKERDREMAALLAGTLDEHDKAAKSKKRKASAMRRLESLGEGQAEVIVAQDARTSAPKEKAWEKALRHGRYASALDQALDPRGKDHSPLGVLTLLLALRHRSAVRDALEGRDERTVQPVLKWTCDHIIDPRYVSVCVEVGMVLVELYAQYAGDSAELFEGFKALKRKVTNEVDRAQTASSVGGMVESLILGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK43</accession>
    <name>A0AAD8UK43_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_627431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1722993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363048.1">
        <property type="nucleotide sequence ID" value="XM_060508631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK43"/>
    <dbReference type="GeneID" id="85392530"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="470" mass="50359" checksum="00BEBB22FFA00F19" modified="2024-05-29" version="1">MASWQQEVPALRADINGDVLLPGDEGYEESLVRWSIVCIKPAGIVVKPKSAHDVSAAIRFATKHNIPFTTNGGGHSTAGTSSSDGGMVIHLASHLRDVTVDPAKRLVTYGGGCTWKDVDAATWKHGLATVGGTVSHTGVGGLVLGGGQGLLSGLHGLAVDCLVEVEVVLADGSIVTASETENADLFWALRGAGASFGVVTRFTSEVFPQGKVWYGALMFANSQLPALVTWANEFVERMDGRQFVIMGFAYGPPGPDAKPMIIVQPFHNGTGKEATEGIFTGLLDVGPLVNMATEMDYPTANTILDELQGPGARRLMGGTNLTAPFELAKWEEMSREFYSRVDEETAKGNDMRGSILAVEIYKKDKVVSVPFGATAYSNRGTYFDCMVLTCWTDPAKDGMIRGWNRVLAAKIKGDNHTGERGGVGQYNNYASSDVGVKEGFGENAKRLVELKGKYDPDNRFSRSPWKIVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKY0</accession>
    <name>A0AAD8UKY0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_314849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365248.1">
        <property type="nucleotide sequence ID" value="XM_060502329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKY0"/>
    <dbReference type="GeneID" id="85386228"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="27671" checksum="F758692DE9880183" modified="2024-05-29" version="1">MAAIVRHYAPGIPLGIDGLRTFVSTLQVAPQEPELPTELAQQGPPANTSSCLPGGGGHLLPSVTAKDSVSPLSEGSFISDATRQRRFNGVSSYAVLQSKVSLCITRSFPRLAALQPSGTFDLREGEPLSNKPDAALPDRKTCERCSVVFLRFINCVFYVLGPERLFDTILRAHGNVDVSVSTQAMIQLIVALIDDDPHHFELASKKMESVIEEGSIESIQAIIVMAKEKPAEHFLGRSRQRHQNCPVTRVARND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULF7</accession>
    <name>A0AAD8ULF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitin deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_753044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363974.1">
        <property type="nucleotide sequence ID" value="XM_060514293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULF7"/>
    <dbReference type="GeneID" id="85398191"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10958">
        <property type="entry name" value="CE4_NodB_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF137">
        <property type="entry name" value="4-DEOXY-4-FORMAMIDO-L-ARABINOSE-PHOSPHOUNDECAPRENOL DEFORMYLASE ARND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="3" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="6">
        <location>
            <begin position="48"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="27579" checksum="F00D99EEAC953A6A" modified="2024-05-29" version="1">MATLLALLALAVLLVVPFYIIYKPPPFVINYFARKWPDVLWQVKTDQKIIGLTIDDAPSQHTADILNVLKENDAHATFFLIGSQMNGREEDTGAIIQSGSELGNHGMHDEASRSLPIDQLESDIFEVRRKIKIAYEYEDKPLVAGYFRPGSGFFSNKMRRLVDKLGYRMVLGSVYPHDAQISSWRTNANHILSMARPGAIIICHDRRSWTVPMLRKVLPELKKRGYRILNLTELLKEVDTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULV6</accession>
    <name>A0AAD8ULV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome b561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_578852</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364395.1">
        <property type="nucleotide sequence ID" value="XM_060505173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULV6"/>
    <dbReference type="GeneID" id="85389072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08761">
        <property type="entry name" value="Cyt_b561_CYB561D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="42"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="245" mass="26754" checksum="E083494A8EE102E2" modified="2024-05-29" version="1">MSSATGLPESPPRGDGDNEFEPLLGRPGDAQQEPDEFIARNLIIGTGIIAQFGAVIFVAMIWAAVLTKDVILFSGHPLAQSLAIFTLTQSILSLQPTHTPEQKRVGQRVHAGLNLLAFLFLVAGVGIIEYNKYLQGPDSHFHSVHGYLGVTVSIILLLQYIVGFTMWATPKLYGGEDTAKSIWKYHRWSGYVVLVLLLVTAATAIDTGFNYNVLKLKLWAVVVTSLLILVGIIPRVQKQKLGFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNL1</accession>
    <name>A0AAD8UNL1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_573194</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367126.1">
        <property type="nucleotide sequence ID" value="XM_060504596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNL1"/>
    <dbReference type="GeneID" id="85388495"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="403"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="844" mass="91728" checksum="062210A7B93D32A0" modified="2024-05-29" version="1">MTISYIAEKVAVFDVEDVVEKLTVQEKIDLLAGIDFWHTKSVPRLGVPSIRLSDGPNGVRGTRFFNGVPAACFPCGTGLAATWDAGLLREAGTLMGLEARAKGAHILLGPTVNMQRSPLGGRGFESFSEDPILAGQSAAAIVAGIQSTGVQAAIKHFVGNDQEHERMAVDSRITDRALREIYLLPFQIAVRDANPASFMTAYNKVNGLHVSEDAAMLQSILRDQWKWEGLIMSDWYGTYSTIEAIEAGLDLEMPGPTRWRGQLVKHALASRRLLPETVDERVRAILKAVRRGALTGIPEGAEEDGRDLPETSTLLRKIAGDSIVLLKNENSTLPFKKEKTVLVIGPNAKAAVYCGGGSATLRPYYAVTPFNAIYEQAKNVVYSVGCYAHKMLPILGPRLKTADGQVGVTFRAYTAPETDSDRQPVDTLHLVDTNMYFADYYHPEITEDLWWGEIEASFTAEETGDFEFGLTVHGTANLYIDGELVIDNETVQRGGGSFFNVGTMEEIGTKALVAGQTYNITVKFASGAASKVKDADGVVSFGGGGVRIGGVEVRDADEEIRRAAELAKSVDQVVICVGLNADFEQEGHDRPHMDLPGRTDDLVSAVAAANPSTTVVVQSGTPVTMPWAGSVSAIIQAWYGGNETGNSIADVLFGNVNPSGKLPLSFPVRVEDNPAFLNYRSDQGRVLYGEDVFVGYRYYEAVKRSVLYTFGWGLSYTTFSVNGLQVSHRVTDGDEKILVRVELNNTGKVDGSEVVQVYVSPQQPSITRPGKELKGFSKTHVKAGQSTQVEVVLSKKYALSFWDEPRKQWAVEAGKYDILVGTSSLETPLVATVKVEKTCWWSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNU0</accession>
    <name>A0AAD8UNU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sec7 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_753326</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle</location>
            <location evidence="5">COPI-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363740.1">
        <property type="nucleotide sequence ID" value="XM_060514339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398237"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030663">
        <property type="term" value="C:COPI-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="7">
        <location>
            <begin position="633"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="587"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1534"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1560"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1840"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1569"/>
            <end position="1581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1859" mass="208823" checksum="19522488D98753EA" modified="2024-05-29" version="1">MSSLKFLVSSLEAIAASKEAQRNKQLTESLQKTLTAIKESDPNFPDPEIVFAPLQLATRTGNVQLVTGALDCIGKLISYSYFSLPTTADGQQDAPADRAPLIERAIDTICDCFQGETTGVEVQLQIVKSLLAAVLNDKIVVHGAGLLKAVRQVYNVFLLSRSTANQQMAQGTLTQMVGTVFERVKTRLHMKEARVNLEKLKHSSSNVTFEQGDSINGTTIAEEKEEDANGEEEEDSTTAPISETEKTPVESEENGNGKLTLKDLEHRKSFDDSHLGDGPTMVTEIKPGRKAARSVSEQSTPESSLEDSPEALDAEDEVYIKDAYLVFRSFCNLSTKVLPPDQLYDFRGQPMRSKLISLHLIHTLLNNNIAVFTSPLCTITNSKSNEPTTFLQAVKFYLCLSITRNGASSVDRVFDVCCEIFWLMLKYMRESFKLEIAVFLNEIYLALLARRTAPISQKVYVVNILNRFCADSKALVETYLNYDCERSVDNIFQTIIEDLSKFSTASVPVTPVQEQQYEERSAKSTSAGEWQLRAILPPPLSVAQITPHTEPENEIPKEYVMKRVALDALVDSLRSMVDWSAAVRQDTNGVRPDGETRTSEDVRPSIDPSMYDNQSRFETPAPSTPVMEDDPASLEKAKARKTAMNNAIKQFNFKPKRGIKLLIENGFIPSDSPQDIAKFLLTEERLDKAQIGEYLGEGDPKNIETMHAFVDAMDFTKKRFVDALRTFLQSFRLPGEAQKIDRYMLKFAERYVMGNPNAFANADTAYVLAYSVIMLNTDLHSSKIAKRMSKEEFIKNNRGINDNADLPDEYLLAIYDEIASNEIVLKSEREAAAAAGTVPPPSTGIAAGLGQALSNMGRDLQREAYLQQSEEIALRSEQLFKTLYKNQRRNAQRSGVRFIPATSFQHIGPMFDVTWMSYFSALSSQMQKTHNLEINKLCLEGMKLATKIACVFDLSTPREAFVSALKNTTNLNNPQEMMTKNVEALKVILELGQTEGNVLRSSWKDVLMCISQLDRLQLITGGVDESVVPDVSKARFMPPQRENTSDSRSSTQSKRRGGRPRSGTGPQGFSSEIALESRSDEVIKAVDRIFTNTGNLNGEAIVHFAKALTEVSWDEIKVSGSNDSPRTYSLQKIVEIAYYNMTRVRFEWSNIWDVFGDHFNRVGCHNNITIVFFALDSLRQLSMRFMELEELAGFKFQKDFLKPFEHVLANSQNIAVKDMVLRCLIQMIQARGDNIRSGWRTMFGVFTVAARETNESIVNLAYENVTQVYKTKFGVVISQGAFTDLIVCLTEFSKNMKFQKKSLQALESLKSIIPRMLKTPECPLSQKGQNAAGEHTASAADTLQRSQNRTSVEEGYWFPVLFAFHDVLMTGEDLEVRSNALEYFFEALLKYGGEFPPDFWDILWRQQLYPIFMVLRSRPDLNNALNHEELSVWLSTTMIQALRNMITLFTHYFDALEYMLDRFLELLALCICQENDTISRIGSNCLQQLILKNVTKFTTEHWAKIVGAFCELFARTTAHQLFSATTINSTASIDMPPNGLEFSGPLSPTEASMEEDNLKINGTEKNGENSDSNSSDANLGSINEDDLKTPTAPVAPQSQPPLEEFKPTSNLQQQPVVVTAARRRYFNRIISRCVLQLLMIETVNELFSNDTVYNQIPTSELLRLMALLKRSYLFARKFNADKELRMRLWREGFMKQAPNLLKQESGAAATYVAILFRMYADDSHERTAARDAIEQALVPLCKSIIKDFVGLEEDSQHRNIVAWRPVVVDVLEGYAAFPVDAFQKHIKEFYVMAVELLGKDLTSDLRTALLLVLRRVGEVGLGIEGMTKVEVDRRDSIISSATENTVDGPEGDASARMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPJ2</accession>
    <name>A0AAD8UPJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_752931</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364160.1">
        <property type="nucleotide sequence ID" value="XM_060514275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPJ2"/>
    <dbReference type="GeneID" id="85398173"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052585">
        <property type="entry name" value="Lipid_raft_assoc_Zn_ADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482">
        <property type="entry name" value="PROTEIN AST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43482:SF2">
        <property type="entry name" value="ZINC-BINDING DEHYDROGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="4">
        <location>
            <begin position="34"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="55497" checksum="95DB24F83B5800A5" modified="2024-05-29" version="1">MAEIPATQTVLILHAAKQPYETEEGYRVPEIQNEQEVLVKTEHIGLNPIDWKAPDFNFAIPTLPYISGRELVGRVVRRPQPSSTAATTTSETQSQSRLREGDQVLVISTDYRDLRKAAYQEYVVTSDFNAARIPPNVSPRAGATLGVAFVAAALSLAVCMGVDFSHVLDGPDLLTILRSVPPESLPQDIRAECLSGIGNHERATAGDWVVIWGGSSTSANLAVQLARLAGLKVVTVVDKLRHGLRLSNHTVLRPDLLVDSHDPARAIDIIRANVGKDLRFALDTSGRESACWLLRALTPSQDANAPPSPPDTPRNSAPTVKHLIGLTGLPKEQAPEAVAYHTVPIKVFHEVPAVGEALVTWLERLLESGLVSPPEVLGVEEGFEGINRGLDRMRKGEIRGGRMVVSLAPEGAGAAEQDVIREASVPLALVDSPMADGVAEEGPQPSETSQASSPEFTAQKLADTGLRRGSATLWQAGDAVPRSFPGKQINDSSNAAPRRNSLWQPKSAEIAVENVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPK8</accession>
    <name>A0AAD8UPK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Na+/H+/K+ antiporter P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_570659</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368307.1">
        <property type="nucleotide sequence ID" value="XM_060504329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPK8"/>
    <dbReference type="GeneID" id="85388228"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000114">
        <property type="entry name" value="H /K ATPase alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="894"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="995"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1036"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1067"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="101"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1106" mass="122261" checksum="2EFF280AC923F1C1" modified="2024-05-29" version="1">MDDESELKHQKEAAGDRIRWDADEEAGRKAHRSSAGPALHHARSNTSMSIHSVRSRRNSIDAAAELPIQYRTVSFEIEEYKTKTEAVKKAKNVATELSELEWHTLSVDELLRRQSSSLADGLSADQVQRRTAHYGKNAPSPAPTNHTKRILGYFFKGFGTVLLVASVLVFIAWKPLGSPPAVANLALAIVLLAVFFIQAAFNMWQDWSSSRVMNSIKTMLPENCMVIRDGNQVELMAENIVPGDILIVKSGNKLPADVRFLKVSSDAKFDRAILTGESVPLPASVDSTDNNYLETRCIGLQGTHCVSGTCTGVVVATGDNTIFGRIAKLTNEPKKGLTTLEREVLHFVLIICSIMFLMIVLVLIVWGAWLRKQYPNWINVPNLIISCVSVAVAFIPEGLPVALTASMTISANMMRKNKILCKSLKTVETLGSVSIICSDKTGTLTQNKMIVTECAIGTMKMTADGTRDKIAVDRHNHPNNNSLEQLRALAGLCNAGQFDAATVRLPLHERVIHGDATDQAILRFSESLGQTAELRRCWQTKYELAFNSKNKYMIRVLGMSHPDGLSLALPSDTASVFQPGDVLLTIKGAPDVLMPRLSNYVNPAGYTTALDPSTRASIEQIKDEWSAQGRRVLLLARKAISRSALKGHPSDSAYEMEINNQAKSGLTLVGLVGIVDPPRPEIPEVMNTLRGAGIRIFMVTGDFALTAQAIAAECNIISVPQSQVDDISALQRINHVDPSIKHIVDDLESSPRQALVLSGPELMTLNEEQWDQLAQYQEIVFARTTPEQKLRIVRELQSRHEIVGMTGDGVNDAPSLRAADVGIALGSGSDIAIEAADMVLLDSFSSVVEALRYGRMMFDNLKKTVAYLLPAGSFSEFWPVMTNVLFGIPQILSSFLMIIICLFTDAAAAIAMAYEAPEADVLLRKPRVPGKDRLVDWQLVVQSYGLVGVLETLSSFAMSYWYLERNGIKFSDIWFSFGNLPSTIDPDYYQQKLNVASSIYFVNLVVMQWFNLLAIRTRRLSLFQHPPIGNKRTQNLYLFPAIIFALLMAIFWLYVPEFQTTLATAPVPVEYWFLPMTFGLGILLIDEARKFAVRKWPTGIIAKCAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ59</accession>
    <name>A0AAD8UQ59_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cupin type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365763.1">
        <property type="nucleotide sequence ID" value="XM_060504876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ59"/>
    <dbReference type="GeneID" id="85388775"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02231">
        <property type="entry name" value="cupin_BLL6423-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047142">
        <property type="entry name" value="OryJ/VirC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156:SF2">
        <property type="entry name" value="CUPIN TYPE-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36156">
        <property type="entry name" value="SLR2101 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin type-2" evidence="2">
        <location>
            <begin position="97"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="211" mass="23396" checksum="2102F079C811CCC2" modified="2024-05-29" version="1">MSSSGASPAAPASEDCPFGPVSRHITTHDANGRAVFSDAFPVQVTPDPLKNMYFHTCYTTSESPVTMDDEKDLAAYAPNHPRMPTLHLPSGSVLRVVDFGPQTGPMMHRTESCDYGIVLKGEVECYLDDGAKRTLKEGEIMIQRGTMHGWKNATDQWARVIFCLQPAEPVRVAGKVMEDDIPFMKVSPERQADYEKFMAEQAAKKKTEEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ84</accession>
    <name>A0AAD8UQ84_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_575541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365969.1">
        <property type="nucleotide sequence ID" value="XM_060504823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ84"/>
    <dbReference type="GeneID" id="85388722"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="1">
        <location>
            <begin position="15"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="28721" checksum="B5A27C8F05323755" modified="2024-05-29" version="1">MSSSPSTAKASPGPAPWRAPFLKNVTDMASPEFNLATIHSSSSSSASSSLTPRLRTVIFRGLWASLLVNPKNTADLNPPLYESDLLTLTTDARMAKVPDFLTSDGGKDDTKKSGGGGPVEACFWTDAKVQWRIRGEAFLLGPDIDGSNTAALREHLLARMRNDWSFAREVTAHFGNLSPMMRGTFKNPVPGTSRAANPPSDTLKLGQKVEDLDDKVARENFRVVVIVPTEVDQTDLSASEDPRRYLYRFRVNGWEKIELWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URM1</accession>
    <name>A0AAD8URM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_664840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368263.1">
        <property type="nucleotide sequence ID" value="XM_060511083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URM1"/>
    <dbReference type="GeneID" id="85394982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF80">
        <property type="entry name" value="NAD(P)-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="301" mass="32324" checksum="034CFD6DC3C6F7DC" modified="2024-05-29" version="1">MTTLDIKETDIPNLAGQTAIVTGGSSGIGLATANILASRGASVILLDVCQPTETLQSSVQFRKCDIRRWVELSDAFSQIGRVQIAVANAGVDEDGTYLNDSYDDDGDLLEPNYDVVDVNLRGTLNFVKLALHSMRKHSVQGSIVLTSSATAYSPEQSLPVYSGTKAALINYLRAMRSNLRDTGITINAVAPAATITGLLPAKLAAPIMAAGLPVSSAHFVGLAVVYSAVAMEAKKVQAYGKDNAEWREASGRWNGRVILTLGERYAELEEPLADCRNIWMGIKNLRETTMQQAATDFRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URU0</accession>
    <name>A0AAD8URU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Branched-chain amino acid aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_570916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368383.1">
        <property type="nucleotide sequence ID" value="XM_060504353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URU0"/>
    <dbReference type="GeneID" id="85388252"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009081">
        <property type="term" value="P:branched-chain amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000010">
        <property type="entry name" value="Branched-chain amino acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825">
        <property type="entry name" value="AMINO ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42825:SF2">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="312"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="42891" checksum="1E08083D7058064B" modified="2024-05-29" version="1">MAAFPPPPVNTIDWSNVGFKIREVNGHIESTYSVTTGKWTPLKFVADPFMRIHGMAPALNYGQQAYEGLKAFRAPGDKQINIFRADKNAKRLQHSADVASMPRVPEDLFVAAVKAAVSLNAGYVPPHETGAAMYIRPQLYGSSAQLGLSPPEEYVFAVFVIPTGVYHGSHPVNALILDDFDRAAPNGTGHAKVGGNYAPVLRFSDRARSEGYGITLHLDSVKHEEIDEFSTSGFIGAKKEGDKITLVVPDSKCVIDSVTSASIQDIGRSFGWAVEKRVIKYSELPTFTEVMAAGTAAALVPIRSITRRVDASSPQSLAGSSQERVSSAKAGEETVTFIPESQEEAGDICLKLLSTLQAIQLGKLKDEFGWNFVVSEADGTAVVGEAKTNGSAQTVDQMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US57</accession>
    <name>A0AAD8US57_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF427 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_617370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366214.1">
        <property type="nucleotide sequence ID" value="XM_060508026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US57"/>
    <dbReference type="GeneID" id="85391925"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43058:SF1">
        <property type="entry name" value="DUF427 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43058">
        <property type="entry name" value="SLR0655 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="165" mass="18612" checksum="F34FDDF28FBEB525" modified="2024-05-29" version="1">MATRARMNVQTFPRPPLLEKISRHLRIVWNGLVIAETRDAYWVLETHHPPTYYLPPAALKVQLTPTRRSTYCEWKGAATYYTITAPEPPSGTLPEVVSNRIWSYESPTPGFEAIKGYLSFYADPWNCFVDGEAVQPQPGDFYGGWVTSEIDGIVKGAHGNWDPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USP8</accession>
    <name>A0AAD8USP8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_149704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368162.1">
        <property type="nucleotide sequence ID" value="XM_060501317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USP8"/>
    <dbReference type="GeneID" id="85385216"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="794"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="825"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="897" mass="102644" checksum="8066581CF9C17831" modified="2024-05-29" version="1">MALLQLQRACERFRSHLSDEETRRVENVKSVEDVREAISQMECYLASRQKLRNFERLVPFLDAADRLTKPIDVLSNGVPFLPYIWAPLKLILQISQDHTHALDEILSAYSRIGASLPRLSRYGNAFPDSHDFQQLLGHIYQDIIDFHCHAYRLVQKPGWAMLFSTCWGRFQHRYDSLLDSIAKHSELIDREAASYEIVQAREWRQKLLEEAQDREKKEEIHQREAVNKWLQVSDRSEEKLERLHNRCLDGTSQWLTGSPQVRSWLQKGREKPVLWLNGKPGSGKSILCSQLIYFLRSNPTWNCLFFFCDFHTTGYGVTVQVLRSICAQIMDLVPETASFIYKEGVVSGKTPSTSILKEFIPKLFSFFEDLRLIIDGIDEIGSSEHGELIKTLARLAETQGNFRLLISSQDIPSIARNLKGRPTLIVGKQSASVCKDIGLIVSSRLEAINEGLDGRVPESVFTEIRETILKRAEGMFLWVHLVLQVLETTDNIQELISSVEVFPKDLEEAYSKILTSIMSRCQATDVSKLRRIFGWMVFSRGGQPMRKFELRLGRVLHADLTIIDERTKPFPNVLDLCKPFIEDGPGATIVFIHGTVPKFLQAQSSGPFINRKDSCRDITTACIAQLIQSLNLADETLERLEHLYCIAQGFYGLLPYAHEYWIEHLLEYLELNQGFCTPDSLSIQRQLVGLTKNWSDRLEKEPARIYNVESLEPRLHWLESLPQTRTLIQQVHEIRKATKEPVDNMPSLEDATLLSSVRTKYHTYVIDLLREVNCPGLWAEDLIAFKEEYGPSAFVCPVYGCDKAVVGFSSASQLTSHSTRHQEKPRCLKQDCFYNDVGFPSPRHLREHQRRCHPPPPPPSIPRQIFQNLDQSLLCISIADLPPTEKLTAAQYVADAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT08</accession>
    <name>A0AAD8UT08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Stress-activated map kinase-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_212353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367394.1">
        <property type="nucleotide sequence ID" value="XM_060501719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT08"/>
    <dbReference type="GeneID" id="85385618"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031567">
        <property type="entry name" value="CRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008828">
        <property type="entry name" value="Sin1/Avo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031313">
        <property type="entry name" value="Sin1_PH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13335:SF1">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16978">
        <property type="entry name" value="CRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16979">
        <property type="entry name" value="SIN1_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIM" evidence="3">
        <location>
            <begin position="333"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="SIN1-type PH" evidence="4">
        <location>
            <begin position="702"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="884" mass="97830" checksum="0F48B1CDAE24D6E5" modified="2024-05-29" version="1">MSVIQNEELVAYQLRCGYLTEIADGVGERLITLNEGFMNSSAFKAVAWQANPDLVKRCYSPPIPTAIASEYFQAPRQAGVTLEDEPDEAGMLTGGGTDTLGPGLATRRRRRRENLEDDDSSDLSDESDDDDAGQRAAQQIKFAKMPVRSRAGSSPIQSSQIKQSPAMSPRAAPGARRGSQSALEVVKERARRDTVTSSEVSSENEFDASGFHKQREAARAAAKSVKLQAKILEEPSLGIKRAGTQLLPEEEEDDSDGSDMSGAYIESIDSASILDAVENPEPPPHKQVVGTPPREFTRTSTIRKSQAPPRILQALPPPRPMSTIRPMSMIQPKSLLSAALRARKTKPKVPFEGFAALSGQGENNPIAVRIYAAFSESPTKPFEVPIRRMVHHGEGGDRPVTVADLIGLALWRYNEEKRQPPIPADKANINWFTLRMVEEDGEVDDDFPPFERNKALTSFTTANNRAAGRMRANSKTYDNFGLVQASQSEYAENQSITPQEEEEPAEEVDEDLTPRNTPQPNLNSFLPVATEPRPNPVTNTTYRQQHSMFADAPQAPAAAPNTSRGQQKLLRVHLHSTDVAPGQLVTLDTTTETYMAEVLDMVCRKRQLDKANHVLKMPGGGPVILLDTKVAAIGSLSDLELHRRRFATDGPLAMTGSPGSASPKLLPFVGDQPGRKSKKPHIMGSHPLAQEAIKQAELTSAYHKAWVVWRLRTVRMITQSEKRFEIDGEYVHIKPTTRDSKTTTAHISQVIGCKVSSKHPNQFKVSWHAYCWAVAARLHKLTRDFYSCSSTGTPRASAMTLKPSRWKKRMRSSTNLRRELHRLWAEHLDPSLHDLMNTGCITSELSCPPPQHYATTLRHVYTATHTNCPVTLRKKRPRTLGWAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTJ2</accession>
    <name>A0AAD8UTJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_227075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367116.1">
        <property type="nucleotide sequence ID" value="XM_060501775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTJ2"/>
    <dbReference type="GeneID" id="85385674"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="328" mass="35609" checksum="6AD06064C86F96BB" modified="2024-05-29" version="1">MLNDDEVSLLARHFHARDDANFFKVAISQVLGQPGVAQAAELLFGRLGLEFAVFHAALMRQVGHFPTTRRMTTAAPSHGSVRASPVPGPALYAPQSQSGLTQQPGDIINAMAALHEQHRLGSLTDEEVAARNSEYLATLRASSEVPSVFSTISSPSPWPARTLPIPADRFGSGPWPATSTLCTPVTMFAAEAGILGYDVEPGWSAVPEEQRAVYRARSETLRREAWAQHETTLAERPAPSVLPLPEQGQHSSSRLSGLMSRGERLAGVPARPGIITGLGKFRDEQEFEWQEVLRRWETLPKEQRQTYEARAATVNASAKAAFDGGAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTS8</accession>
    <name>A0AAD8UTS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RCC1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_649485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367683.1">
        <property type="nucleotide sequence ID" value="XM_060510285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTS8"/>
    <dbReference type="GeneID" id="85394184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF5">
        <property type="entry name" value="RCC DOMAIN-CONTAINING PROTEIN ATS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="4"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="131"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="186"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="278"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="38979" checksum="24B4B32EE38520EF" modified="2024-05-29" version="1">MSVLFAVGSNGSGQLGIGHKEDVSVPKQAIFFPEDTESPVVKIAAGGNHTLLLTKSGQLWWSGDATSGACGLTSAAETDESVFQQVQLSKDEANAAPATAAGTTTASTTVLIAATWEGSFVVQQDAEGKKTKLFSFGAGQKGELGLGELLVRSPSATLFKEFPPAGTEIVDLAACMGHAMAVLSNGDAYAWGNVRKGQGGAPEAVVYSPRKIEGVEFKVERAVCGKDFTCLFGAPDSGKLLVLGSDKWNIKSSAPSSVPEWTDVGASWGNVYVLKKDGELMAWGRDDHGQLPPPSLPKLSKIAIGSEHVIAFTETGDVLAWGWGEHGNCGPQVENNDVKGRWNVIASSRFIPPGSKIAGIGAGCATSWVTIITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU67</accession>
    <name>A0AAD8UU67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367234.1">
        <property type="nucleotide sequence ID" value="XM_060510309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU67"/>
    <dbReference type="GeneID" id="85394208"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="23767" checksum="9B9CEE6450C271CF" modified="2024-05-29" version="1">MMSTGAGRQGMLNFRVTHPDVFTHGICGRKDCYRGSPAAADCEFHGNAVRDIIRSRRDQRRARLQQRCRTHSIGGSIDMTPTAATASASASTSRSVTPLKRQPSQSSSISKPDSPLSFTSSEFSADFSPCVSPLMEDLMLEVTDAIESSGHTPERLAMPPRRTTSAFNMDDIFRMIDEAQREYESLSDAPVTPARSRNEIPRKPRWSWESLLGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU89</accession>
    <name>A0AAD8UU89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_572999</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367264.1">
        <property type="nucleotide sequence ID" value="XM_060504579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU89"/>
    <dbReference type="GeneID" id="85388478"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="21979" checksum="4DFBC98B548B5A91" modified="2024-05-29" version="1">MAEIRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAVDSPDSLDNVQEKWISEVLHFCQGLPIILVGCKKDLRYDSKTIEELRKTSQKPVSPEEGEEVRKKIGAYKYLECSAKTNEGVREVFEHATRAALLSRSRSSGKKHKCLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVF7</accession>
    <name>A0AAD8UVF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4 11">4.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_613949</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>L-homocysteine + L-serine = L,L-cystathionine + H2O</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4 11"/>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367070.1">
        <property type="nucleotide sequence ID" value="XM_060507787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVF7"/>
    <dbReference type="GeneID" id="85391686"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004122">
        <property type="term" value="F:cystathionine beta-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04608">
        <property type="entry name" value="CBS_pair_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000118">
        <property type="entry name" value="Related to CYS4-cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046353">
        <property type="entry name" value="CBS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005857">
        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 10 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="372"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1727015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="55555" checksum="4F03B120290DEB7F" modified="2024-05-29" version="1">MGDAINATRAAVTAKSATELIGNTPLVRLNKIPQSLGIECEVYAKVELFNAGGSVKDRIALRMIEEAERTGRIKPGDTLIEPTSGNTGIGLALVGAIKGYKTIITLPEKMSAEKVSVLRALGATIIRTPTQAAWDSPESHIGVARRLEKEIPNAHILDQYGNLDNPLAHEFGTAEEIWAQTGGKIDALVAGAGTGGTISGIARGLKKHNKDVKIIAADPHGSILALPESLNKEHENEGYKVEGIGYDFIPDVLSRDLVDKWYKTEDRESFQLARRLIAEEGLLVGGSSGSAMAAMVRAVKDLGLGKGQTVVVVLPDSIRSYLSKFADDDWLAANDLLPEVNGLETQATTNGAATSAKGSVDPYEGATVSALRLKPVMSVPATSPCSEASEIMRDKGFDQLPVLSASGHKLVGLVTLGNLLSYISSGRATGSSPVSDVMFDFGRFDEVVTDPRQAGETGEKSKKKRNFVEITLDTPLSTLSKFLEWNSAAVVTEKAEGTKNLSKPVAVVTKVDLLTWVVNKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVP2</accession>
    <name>A0AAD8UVP2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_748969</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368609.1">
        <property type="nucleotide sequence ID" value="XM_060513697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVP2"/>
    <dbReference type="GeneID" id="85397595"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11842">
        <property type="entry name" value="SH3_Ysc84p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="354"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="414" mass="43413" checksum="BE41BDCCE8C300BB" modified="2024-05-29" version="1">MGLHNPLPSSMASECKKCGKILTSFIDPRQAFSPDKIIPPSVLANAKGLAILTVLKAGFLGSGRFGSGLVVSRLPDGSWSAPSAIGTAGAGFGGQIGFELTDFVFILNDASAVKTFAQAGSLTLGGNVSIAAGPVGRNAEAAGAASLKSVAGIFSYSKTKGLFAGVSLEGSVIIERRDANEKLYGTRYTAAQILTGSVRSPPQAAPLMNILNSRAFNAGRTGQANDSMYNDIPVYDQGQGQDDWNGNNSREFGNNNRSSVFGGGDSGASEFGGPKRSSTWQDDVYDRPAGGGFGGVSRSNTGVSRSNTFASRGNDDYVYRDNPSPSYGLNDQKTGPPGRPAAPKPNFTGKAAMLKKNEAVALFTFDADQPGDLGFKKGDVITVLKKTESETDWWTGMIGTRHGIFPSNYVKMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8V7</accession>
    <name>A0AAD8X8V7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_640695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000173">
        <property type="protein sequence ID" value="KAK1710309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358779.1">
        <property type="nucleotide sequence ID" value="XM_060509511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8V7"/>
    <dbReference type="GeneID" id="85393410"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="252" mass="28408" checksum="B3CE3786918E93C4" modified="2024-05-29" version="1">MLDLDRGTHAVASSWMEQGPAEGLAEEESLTFGVSSLSREEEDSEGRGGGGGGGRSHTTCNCAAGGRDLVMFGARIILSLLLYAVRPRHFSGAVLRMYLCVIWCRVYGFGSDFDYWMGKQGIMVRLPCFWTCKTMDTITRVKRWETRHEILKKTVRGSKTRPWFLVLSTTVSRMPRCCRVAWDSDWQSWLSNTICILGVRQPRTRKQNRVRVSWPWSVSMPDELHLLASIGSNYGVKCRSLLFPGSSIKGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X996</accession>
    <name>A0AAD8X996_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_723750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359229.1">
        <property type="nucleotide sequence ID" value="XM_060512595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X996"/>
    <dbReference type="GeneID" id="85396493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23513">
        <property type="entry name" value="INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23513:SF6">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY ASSOCIATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="540" mass="60395" checksum="9CEDBBF43999B3A0" modified="2024-05-29" version="1">MAILKDFVERLKSFSPQERRAIFFYICGIMLYKFGLEAFNGSITALATNRYDYESDTRGTPSRTFERLGLLQGLNQATQCVGSILIAPLIKHYPTKNVLSAAILLFGLMTAILLILDAATGGTFVPEAYRKKHPKDEWSYYGDYNNDAIIPIYTVTGIAYGMVELIRRVIPRDIVGGNVQKLRQMDSLVHIFYEVAGTSGAFVTALVMIPNLGNNRSFVITPICFSLAAILWFFVVDGSHDRNALARAEARKSNYFINIGKGFLLFFESIWVGAKILFTSTRFVWLVPAYGVALYGHRYLENGIAPQVARRYLGNSAWSQIMVGGSNFGELLGALFVFLFTNVIKTPIPWLRLDALMLLIVWYIPYWYPPSGQVGQAWIVAATFLPVSFGWAAGDVSLAAFIQASLARLEDKENRVSPLGAVMAFLYSFYIVTYAIAGTFLGRYLDGVYNRTGSVREALVNTAGVHFTVIMVTVFASTFIPKGSRCFNPEMLDDTKLDEDIEESRVAKKTLWRSLRSTKHIEKGDERFGRRPDVPVNLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9F5</accession>
    <name>A0AAD8X9F5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CVNH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_121570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000163">
        <property type="protein sequence ID" value="KAK1711184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358987.1">
        <property type="nucleotide sequence ID" value="XM_060501152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9F5"/>
    <dbReference type="GeneID" id="85385051"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042151984" evidence="1">
        <location>
            <begin position="18"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="132" mass="14049" checksum="40C4C5C42702B9A6" modified="2024-05-29" version="1">MKTFSIVVAMLASLVAAGDFSKSCTDEHIDPATQVLTANCNAGDGKGTVKSTSLDLNQCFTYTGTKIQYSGKGHLGDSCSDCYVYRIEDPVYGPIFGTTRVWLSCSCNGSESQIELDTTPVSNQYGTLSCTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9K1</accession>
    <name>A0AAD8X9K1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ribose-phosphate pyrophosphokinase 1</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphoribosyl pyrophosphate synthase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_723505</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359559.1">
        <property type="nucleotide sequence ID" value="XM_060512568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9K1"/>
    <dbReference type="GeneID" id="85396466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000017">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000043">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF57">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="18">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="220"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00077829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1712943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="53397" checksum="5D1EA735154BC334" modified="2024-05-29" version="1">MRGTLIFAGSSCPVLTNQICENLGMAPAQAELTQFSNGETSVRILTSVREKDVFVVQSGSAKVNDTIMELLIMISACNGGSANKITAVLPYFPYSRQSKKKSHRGAITARMLANLLGVAGVKHVITVDLHASQMQGFFKCPVDNLHAEPLIARWIRHNVPNWKEAVVVSKNAGGTKRVTSLADALKLNFGMVTTEKNRKGTNMTSSMIMHHLDNLDRDPVLETTREPPRPSTPPAAPGRAARIRTDAQGSPQFTSAPRSHPRSMDDRPTTPTQSKPGDGSVDDDEEEGDAEYDDRRAHEVTHGRLVQGHIVDDDYPSPAASTVSGSVQGDDPMTMSHASSFFAPEPHALGGSGDAAPESDEEDEVLKDPKVEHMITLVGDVKNRTVFIVDDMIDKPNSWIAAAETVVKKGRAKKVYCMATHGVFGGDSLDQLQACECIDTILVTNSFPIPEDQAKRCPKLVVLDLSFLLAEAIRRNHYGESISPLYQHILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA89</accession>
    <name>A0AAD8XA89_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThuA-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_796324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359872.1">
        <property type="nucleotide sequence ID" value="XM_060515864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA89"/>
    <dbReference type="GeneID" id="85399762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469:SF2">
        <property type="entry name" value="GALACTOSE-BINDING DOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469">
        <property type="entry name" value="SECRETED GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041931760" evidence="1">
        <location>
            <begin position="20"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ThuA-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="29847" checksum="72620C1A9DBEFB9D" modified="2024-05-29" version="1">MLTTLLAAAAIIASHVVHASISATPSLLLFSKTAGYRHASIPHGIQLVSSIANEKGWSVAATEDSAIFTNGSLSAYSTLVFISTTGNYLSTNESDALNDFLLNGGSWLGIHAAGDFGDDMPNWFTKLVGAQFRSHPCETDDICDDAQKERYPPNGNIRPDTVTILDFDHPSTSGFPESYNRTDEWYAYKTNPADDSAYKVLAKVEETYIDEITLSPELQHMPPMHSISWYSMYEGVARAFYTGMGHTNESYSEEYFVKHVTGGLEWVTGTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB83</accession>
    <name>A0AAD8XB83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_158310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000199">
        <property type="protein sequence ID" value="KAK1708206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358238.1">
        <property type="nucleotide sequence ID" value="XM_060501376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB83"/>
    <dbReference type="GeneID" id="85385275"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="578" mass="64951" checksum="B7FF43855672256E" modified="2024-05-29" version="1">MSSSSINPTSIPSISALRRQLGYGDSDVAKDQSMSFQHTVRAFRKTFVTRQGYEGSAMYEWKSSEHQSALEEMVQAFLDRDGNGARLWPDENAQGSAKQLKYSRHGANIKRTLKQLFWRMNLQQHRNGKSRKNKRKTGNVHIRTLDGRGRHEDPIDVDEIEESLGSSGAVEMLTTSSSSKTDNAAAPPKIVDPYEIDSTSEEIQGLLHLQTAVGTDFQHEPEGHDQGVKNTSDSFAVMSPTGPTGDRQLAPYAEMNPSEPPPKRPRVDTLQSLHQTSKKKREDDSVDPQASRTSPRKRNAPQRDGLVTGERLTEALQDMDKDSPPEMVADAMSSKTHLEVPGGSFTGLQEESSLHIHENSAENVTDRETSVDAFADEMVTRLTAETEIHSLQQDEVVTSTETSEPADTSRQASPAVERKKTVSFLANMRRSQTMAAEPIESNDSPQTAPSRQARVKFVYRIITRYPTRRSCIWKPRGSFRTKTLAELEDELPLRFERSELKYLLVRLEARDTLADQIIPCGREEEFDALKRHLADFIRHRIAESLPGEEVSVFIDIEPLPTLDSTEKSSEVEQIMFDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB92</accession>
    <name>A0AAD8XB92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_755710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360907.1">
        <property type="nucleotide sequence ID" value="XM_060514653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB92"/>
    <dbReference type="GeneID" id="85398551"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF14">
        <property type="entry name" value="SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE BLR2146-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1717420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="26995" checksum="58505E04336331B2" modified="2024-05-29" version="1">MASVEGLRVIVAGAATGVGAGTAKLLAARGAKVVVADINISAAKQVGEEITAAGGSALVVEFDLSDEESIKNLIARGTEWLGGGLDSLLNIGADLSPQNLGNDKSVLDMDAAVWQRTFLVNTTGYALTTKYALPHLKAAGGGTIINISSMGGHYMGTPEPIRVAYAASKAAVHALTRHTAATYGPDNVRCNTVALGPILTAALERGIAASPAMQEGLKRVPLRRLGKLEEVGALLAFMISPDAAYITGDIWSINGGTHVMTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBB0</accession>
    <name>A0AAD8XBB0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_770694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000237">
        <property type="protein sequence ID" value="KAK1705781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357685.1">
        <property type="nucleotide sequence ID" value="XM_060515349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBB0"/>
    <dbReference type="GeneID" id="85399247"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF1">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="253" mass="29242" checksum="FF5D03A94644350E" modified="2024-05-29" version="1">MIVSAPMLHSSEAQCRDDDWTGLRDRAERRKRQNRLNVRAYTHLRVAAKRFVICAQAQRPTRHHHNGKSSSAKHVPPYFRNPTTWFPLYKEHLIPLVFYNVFRATITNIHILSLTSLLTSPCTPDLHTTPLFPTPCQVPETLKPTPTQSSTPHECWIDIFPSGGMRDNAIKFRDQFSQHDLCADLVGCQEGDACLNQPGIIAWSDPWHPDGWEVTEKFVEKWSFLLKGCEDVMRATNKWRAMRDEEPLVWELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBL0</accession>
    <name>A0AAD8XBL0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361719.1">
        <property type="nucleotide sequence ID" value="XM_060508904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBL0"/>
    <dbReference type="GeneID" id="85392803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="43266" checksum="2DCE554ACAC08047" modified="2024-05-29" version="1">MSFTRKAKGDPNDTELCKRLWPALADKVYLSGQYMTLATCVRSTLNTWRYSLNQLSPGIENIGKVFEAMDSIRKSPQMPRESLVEAFKPSAANLGNQDCDVQNVISLTASLATMTMIQINPEPNTFSGPVAIWNPTSSLGEAVSDFYQPTPDPELKAAALDTHLTACSLAKFQGYTIVWADFLNEHLRIDEELRLVWIFQHKIWLSSQVGRPDCLVPQSVLLEALDTLNVLLPPDDDHTRRFLQRREQEFYSLGYCGRVPSTDLKKYAIWGTKMDRLLSVAKGPRRGIWQFLPTPDRFNVLESANFVIACVALVFSIVGFVLGLVSIIYAKLSYQIGLESIDISKVSLDVSNESLELTRLQYLLSVAQACSDPDQARLLPDFCSAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD13</accession>
    <name>A0AAD8XD13_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_584497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361811.1">
        <property type="nucleotide sequence ID" value="XM_060505762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD13"/>
    <dbReference type="GeneID" id="85389661"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="134"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="389" mass="39945" checksum="AB68E92228ABF3CE" modified="2024-05-29" version="1">MGVPISNLNAADLIPNKYIVVYNNTFDDDAITSKMSSFAASIKKRNIGKRSLDGRSLSTSTRNFKMNAWRATVMEADDSMIMSVMNAEEVAYVEQDAKVKISATVSQTNAPPGLVRMSHAAAGEAGYVFDQTGGDGITAYIVDTGILTTHSEFQGRATFGANFINNVDTDENGHGSHVAGTIGGQTFGVAKNVNLIGVKVLDGDGAGSNSGVLDGMQFVIDDVAKKNLTGKAVMNMSLGGSASAAVNRAIQALNNAGIVPVVAAGNENQDAANTSPASAPNAITVGAIDARNDRKASFSNFGTVVDIFAPGVNILSVGITSDTATNTLSGTSMASPHVAGLAAYLMGLEGLNTVKAVTDRMLALATASGASVQRNTAGTTNLIANNGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD93</accession>
    <name>A0AAD8XD93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_626020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363519.1">
        <property type="nucleotide sequence ID" value="XM_060508529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD93"/>
    <dbReference type="GeneID" id="85392428"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042112789" evidence="1">
        <location>
            <begin position="32"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="117" mass="12305" checksum="E6FE36D7EA9574BA" modified="2024-05-29" version="1">MGVACPGASPCRPIFRIMLSAFLIAVHVAYAQECNYAGGWSLRFPSSSCPQDAPFECGKAGGLQVRCCPSGLSCAGNGSYDGNYCCPDSTDCSSSAYNHPKVPRAVPQCDTPRRVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDK9</accession>
    <name>A0AAD8XDK9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_629163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362426.1">
        <property type="nucleotide sequence ID" value="XM_060508749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDK9"/>
    <dbReference type="GeneID" id="85392648"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041960027" evidence="1">
        <location>
            <begin position="24"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="14274" checksum="D2CF9E36E08792E7" modified="2024-05-29" version="1">MYTPSILTLLAAAAFHLGTPVSANYESGKAVQINFYSNSGCSAYTSETAAWWTRSPHAAEYVNGGSAGDCFSLGMPGASGSLNVAGAWRGNGAQTGGGCDLYDGYNCGGAKGRIGFNSGSGGCVASRSSNGLLWKSAYCGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDM7</accession>
    <name>A0AAD8XDM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VPS4-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_588802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359965.1">
        <property type="nucleotide sequence ID" value="XM_060506175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDM7"/>
    <dbReference type="GeneID" id="85390074"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013640">
        <property type="entry name" value="Vfa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08432">
        <property type="entry name" value="Vfa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="23437" checksum="9D2E18035091F2AD" modified="2024-05-29" version="1">MSFSNIYTHRKVAETAAKGCDVCYRATSSVLVAPENKDFFYVCPSHLKDKNFCSPIIDKEAVEAKKKKALEDEVARVKKEYEDKQKKKKKEKEEKEKENDKDKEKEKEKDKDDKKTEDEKEDSSKASSLIPACCFLNPSDNCFKDGTETPSLAAEEEPRVFALQKNFFGARIEKKRQMEIAKRNRERLQQPNLFPSVPKGMPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDZ8</accession>
    <name>A0AAD8XDZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_625789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363742.1">
        <property type="nucleotide sequence ID" value="XM_060508513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDZ8"/>
    <dbReference type="GeneID" id="85392412"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115342" checksum="EB49EEC5CEA94787" modified="2024-05-29" version="1">MANIGNFQTSLVSVRNEISPALVNVNLDISLFRGNPAVEFQRVGSALTAWRRKEAEDGILHKTACRLGFLFNDILPDTPELLKAIGIRASDILDSPNINPQGTTQDGPFKDFIGADGTCIWAAATSTPASIGAYLLACILARVWDAKTATSIWVELIHDRKAQVQALIDARRPVNPYTEAANYQDITRDDLAKWDASARAWLRRADRSMDLKHNQFTLIMNNVNTPFIDTGTMYEKVTRAWIRTLETMERLLNNKPQQADDKLVLFAISSWHLYPNLLVFQKETTNVVFGDKLFHDSAVLSLGLEYRMDQKGNFKTWSLALSHLRYYGNPVSVRSEESLDQRITSKQVWLVAMGTTLRQWQVSLSNVDDSIAWFEKLGKVIQETAQRNSVEISWLRRMCDAVLSFSTSSDSEQKMTTALVKFGHRRALHFLGSQGAVRNPYFGLADPGMFRGKDKHKTIEVGFQCLRKLAARAKLRPDQTVLSYTDRTLDGIYTEWATLTPQDASVTGVSYRSHIERAGTPVKRNARWISFRPDKRASGLEKSDRTSRRAREISLAGDACKVVLNTSDVPQYHNQNQHQHSTSLKTPKDWTWENPPPLFNEPGMVLDMISFSFSDILGLEFDILVARGQRTTRGLDIADMYLQTSLLCLDNSPDPDTVMRKLLSSNVKETKGQTKHGAQTVAELQPPSNTSTASESSQNSLRSAPLEWLVSLRALEIASALYDNMPTATISLRIVEQKLHKARWLPESLRSEHVGSANNVLSTSTEEYCRNMSRENSLACIAMFESGIFNISTDETRDVIAMSCEDSIFVAGILLSDPRSSSLGNLGMNFRHLVGNVGKPGMVLMIAPRDPMIRARKYNTSMIQHQIYDGKSRDSFQGTSLHLSFTDWKLPLGSVDGRGQTGQIDNEVVLIESVIAVQQDGQWVADIDVLQIERAGLTTVDDFECICDRGDLPEVDIVTLDSWEELLDPPASPAIMRANKNWAARLAAASILTQQGHNHCLAVLGDDSICWRCLNEAYTDPEPHFPNFIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE45</accession>
    <name>A0AAD8XE45_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_370893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363907.1">
        <property type="nucleotide sequence ID" value="XM_060502632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE45"/>
    <dbReference type="GeneID" id="85386531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042098437" evidence="2">
        <location>
            <begin position="26"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="169" mass="19028" checksum="6483238420812228" modified="2024-05-29" version="1">MLYLAGFGFTLNSSILVSLQSTLLAYLVRPPPSCRGLCMSKRCQPEVRGPSCPFESISRRPGGGGRKTTRRPASTLYGTNGTNGDGTTTEPTATPDWRVCVPFLVGGIRGREESVWRIQPVYVRIGPFPTEVWANSAYYRRTRQPKYRPYGEFFRHIEEYAYASVLYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE58</accession>
    <name>A0AAD8XE58_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_625045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363952.1">
        <property type="nucleotide sequence ID" value="XM_060508478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE58"/>
    <dbReference type="GeneID" id="85392377"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="55" mass="5921" checksum="9DD9DCE541000B41" modified="2024-05-29" version="1">MVGMSSSSTPVADNLGRSLVTELCSFMASTHARRPRFSRPAAMAPDVVARSRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE98</accession>
    <name>A0AAD8XE98_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_622435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364629.1">
        <property type="nucleotide sequence ID" value="XM_060508331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE98"/>
    <dbReference type="GeneID" id="85392230"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01806">
        <property type="entry name" value="Ubl_NEDD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000023">
        <property type="entry name" value="NEDD8 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038738">
        <property type="entry name" value="Nedd8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="77" mass="8570" checksum="3D3F3A89D48A73CC" modified="2024-05-29" version="1">MLIKVRTLTGKEIELDIENEYKVSQIKEKVEEKEGIPPVQQRLIYGGKQMVDDKSASEYGLEAGATLHLVLALRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEB2</accession>
    <name>A0AAD8XEB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_677698</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361643.1">
        <property type="nucleotide sequence ID" value="XM_060511174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEB2"/>
    <dbReference type="GeneID" id="85395073"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF562">
        <property type="entry name" value="ALDEHYDE REDUCTASE II (AFU_ORTHOLOGUE AFUA_1G11360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1720132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="348" mass="38642" checksum="C0035049A5EB6C99" modified="2024-05-29" version="1">MTPERKFAIPKGSTVLVTGANGFIGSHVCNELLQLGFNVRGTVRDVSKCAWLPEALKRQRPKGDFMLVSLPDMEREGAFDAAVEGVSAVIHAASPVSFSPNPESVIPRSITVALNALKAANKAASVKRFIFTSSSVAAALPQPEKKGIEVNSDSWNTESVEIAWREAPHHPQRAWHIYAASKVEAEMAVWKFYHENIRRRYDLIVSSVLPGTNFGRALDAANQGHSSTSSFIESLWNGTHADRLASIPPQYFVDVEDNARLHVAAAVLPNVRSERIFAWAEPFNFDTVLDILRTHFPEKNFVDNFHHYRELSVVSQPQSRAVELLRQLGREGFVPLKQSVLLNVEDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEV8</accession>
    <name>A0AAD8XEV8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_384407</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363821.1">
        <property type="nucleotide sequence ID" value="XM_060502734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEV8"/>
    <dbReference type="GeneID" id="85386633"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="325" mass="36630" checksum="CAB625D6CE826AA4" modified="2024-05-29" version="1">MGEIYRCAETVHVWLGDIDADEVAVAFSNIRMVHAIPATEPYKTDLCKSLAMLTQKPWFTRRWVIQEVKLADRAVLHYGEHSLEYARFRAAWYSVESRMLSRDSLGDLRLLLKHDVTEDLLELLWGFHMAKCSDPRDRLAALYGFLPQSKQPIDLLYSQISWNEIYRRLAEKLINEGALSASRVILHLFAFGPVAGQSLDDAEYPSWVPDWSGVRQLGLASGESNLDRQHSTDRADKPWIEISNEVGGLETEGPSSDPHLDDSLSSREKEMSWFRGAQQDILNANRPFELISFGSQSQRDFLLGKGNYGSGGHQFVAASMGGVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF09</accession>
    <name>A0AAD8XF09_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_431144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362393.1">
        <property type="nucleotide sequence ID" value="XM_060503051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF09"/>
    <dbReference type="GeneID" id="85386950"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="166" mass="18622" checksum="28CD6D064114E89E" modified="2024-05-29" version="1">MSTARRRGVFSGLLLLFLRSRSSFPFPLPFRPLALSLSLSLSSSACLPIFRRACQRLSLVSSVQLHLKAISPVIISHSHLSSLVTSFLCLFYCSSSLPQSFITIVHYLTHPLESSQSLTRFAKFESPRLLHTQQRKPSTENSNQPTRHPSTTLSQSTHTNTHSHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFB5</accession>
    <name>A0AAD8XFB5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_651153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365784.1">
        <property type="nucleotide sequence ID" value="XM_060510432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFB5"/>
    <dbReference type="GeneID" id="85394331"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="29562" checksum="400B7504E2AC03C8" modified="2024-05-29" version="1">MGFEAWILAGKSNPAFSSARRHLRRASSTQQNSDRRDEAEASTGLGAYVLVVDTIRFHETGQKFVASRNAKPGFHAFEVNTPRLLRFAPEAKASAFPHRLSKSTTTNGPYLGPYDVIQRTLCQEFTCSPSDTSNIISKLNHPKTSDRTTIITTLADMGLFGKSTPTEGPGSDEPKKSLYQRYQDKKSGRDTQISDEDLQKYTGKTKDEINDWAKDRPGVAGNRAAGTLTAGPASGFGGMATAGGYGGWGTDAGSDPKHPPPQKERKEVDDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFS5</accession>
    <name>A0AAD8XFS5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_444405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361915.1">
        <property type="nucleotide sequence ID" value="XM_060503134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFS5"/>
    <dbReference type="GeneID" id="85387033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042132225" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10645" checksum="53FB41C57083B4A2" modified="2024-05-29" version="1">MIPSQKSGAASCLFLAALLSVKSKLQDSSLRWMSHPLIYLPGNHIDLCLTGSLGSQTKPLANQRSRMREISMKEGEMKLKEQNARGRVTKQVTCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGN2</accession>
    <name>A0AAD8XGN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_615430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366592.1">
        <property type="nucleotide sequence ID" value="XM_060507893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGN2"/>
    <dbReference type="GeneID" id="85391792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="58" mass="6259" checksum="B6B124FD8D98BD6B" modified="2024-05-29" version="1">MVTHRDTHTQPTPGRGGGWEGKAATNHRTTHPYTQLKPIGRNKESGESLSTGHIPTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHG9</accession>
    <name>A0AAD8XHG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exportin 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_572510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367477.1">
        <property type="nucleotide sequence ID" value="XM_060504516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHG9"/>
    <dbReference type="GeneID" id="85388415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000266">
        <property type="entry name" value="mRNA transport regulator MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057941">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058537">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF53">
        <property type="entry name" value="MRNA TRANSPORT REGULATOR MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24138">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24139">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="971" mass="109137" checksum="D5EF2B8619A8DE87" modified="2024-05-29" version="1">MATNGASEAFAPQDVLSAMVTMRGGEQENKKKAHAYLERFQKSNSAWSTIFGILKDSAEPEAQLFAAITLRGKITYDLSTQVPEAELPALRDQILLLLKGFAAGPKPIRVQLCVCLATLAVQMTAWKDVLPTVVSSLGDSVESHAAILDFLRVLPEEVTEGRKITLTEEELSERTKELLGDNTDQVVQLLINYSQSSASAAQNPQLMECITSWLREVPVSTVVNSPLLDVIFNGVGNDSASQEAAECLCTVFRETRDVDDNLETIQILLPRVIALRQRIAVVVEEEDTEVYKSLTKIFALAAEAWVVAIAREPGHFRPLVDAVLECAARDKDRDVIEHTFQFWYELKQYIVLERYIQARLELVDIYSKLVDILLTHLRYPQSESASETDLFDGDREAEEKFREFRHQMGDTLKDSCEVMGVTDCLTKVLEAIKIWMHSYAGQATATSVPHWQELEAPLFAMRAMGQMVDKEESIVLPQLMPLLVQIPSHEKLRFATIMVLGRYTEWTAAHPEYLEPQFNYIVTSFQTDSKEVVRAAAMAIKYFCTDCKQLLSGQVIQMQEFYDQILDKLPDQSQEEITEGVASVVAVQPPTEIYKLLKLYCDPLVQRLMNKANLATDDKGKLALADHLQLITIFIQIVVPYVGPGEENPAVKYWQEVFPVLATILDNFMGFVPICERICRCWRNMIISYRTAMTPLLPEMANKLAGGFAASRQGAFLWVTAAILREFSEDREHVNQEITQSIYAFFEAQTTTFLRVMSELQPSELPDVIEDFFRLLIDALLYYPGRIVPSELLGPIFEAAIYALTLEQRDPLSATLHFLRDLLTYGGDNPATSDVLPPDVAAQIREVVSKLLATHGEKLVKQVMAGMMITFPRDCFADGSGVLLAMFELFPAQTTTWVENTIQLLPPGTITPAEANRLMAKIKERLSGNDPTAIRQVRALLQDFTNTYRRRYVAPREGLGQLEAARFHFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHP5</accession>
    <name>A0AAD8XHP5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_252865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366791.1">
        <property type="nucleotide sequence ID" value="XM_060501941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHP5"/>
    <dbReference type="GeneID" id="85385840"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="15923" checksum="15CB8793EAF43896" modified="2024-05-29" version="1">MFQPNPQDHLHLRLHRARSVILTAEELVEIRAAQRTFEGAYMRTALSQFSFALIILKIFTSEFYAIGALFAVYGAAVMLVAIFRRHEGNRQFFTSPKVDEGSGVASGGVVRKFRTSGNSVAMLTVLSLAAYVTLLVLTWQLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHW1</accession>
    <name>A0AAD8XHW1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mRNA splicing factor RNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_624597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363970.1">
        <property type="nucleotide sequence ID" value="XM_060508453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHW1"/>
    <dbReference type="GeneID" id="85392352"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="242"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41627" checksum="CB5B5036C230DC5E" modified="2024-05-29" version="1">MAPPADESPATDATPAPAPILFRANRKRKAGLRQRAASPTADDDNDTIVASKSNSTAENTTTPASATEITADDGPEANIPSALRHRARKRLNGVGFSVRGATTLVAGDDTDPVSLSSSLSHALVPATAQTPDDDPLIAKRFAPQTGAAATTIVNKHMMEYIESHLSNRNPPPPPSEPSTSSQHQAAAAAVTNPSTSAPSAGPAELPDPKNHPIMQGKLMEVDLGDEVRARNQAMTEKAARRLLGEAVDEDTGGRRAKKPRLGRDGKPWRPRNRRTSDDIKRDQLVEEILRENRLDVYDVPKPQEPQNEGDGDADDRIAEEFRREFMDAMVQRQQKKKTAAPAARAGARKADEEVLKGPKLGGSRNARAAMRDLLLKKEKEKDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI31</accession>
    <name>A0AAD8XI31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364195.1">
        <property type="nucleotide sequence ID" value="XM_060508391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI31"/>
    <dbReference type="GeneID" id="85392290"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="18222" checksum="58CBC49245AE8A51" modified="2024-05-29" version="1">MSSSAPPQPPTSEAYKTASNPTTRNPAENAAAHDASDRETAARDAALGRTPFPQSQSRSVDDATPSSLGAGVHSSGPVDETERRNTAYVSEGGGSRELENPNVEAEQMATLAEGKVADAVERKSGTQKVPGQEVVNEEFGSGIEEKKKEQQEARDAIKKARSEGVDVDGGIGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI47</accession>
    <name>A0AAD8XI47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metalloprotease MEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_579153</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364255.1">
        <property type="nucleotide sequence ID" value="XM_060505209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI47"/>
    <dbReference type="GeneID" id="85389108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042112412" evidence="10">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="136"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="28353" checksum="50B232A7001B69D8" modified="2024-05-29" version="1">MMSRAAAALLLSFGVSSVLGSLRCFNDDLVAVETPTIALPAYVKRQESKPVDVYFHVTSTVANKDRITDAVIDAQFEVLHSTYLKHGFELNLVNVSRIVDDVLGKGFYEESGIGIPDFEGYVAWRTATRRGGYDALNVYFFSDLGASLGGQCALAGVVQEGSQQFYTDGCWVNGDSMPGMTPRSGNDTTPRKGHVAVHEVGHWFGLLHTFHGRFCEGINDQVADTPAQAGGSSGCPVGRDSCPDSPGLDPIHNFMDYSDDTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIM0</accession>
    <name>A0AAD8XIM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_751094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366323.1">
        <property type="nucleotide sequence ID" value="XM_060514009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIM0"/>
    <dbReference type="GeneID" id="85397907"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="210" mass="22528" checksum="5A3060D915959529" modified="2024-05-29" version="1">MASSSSSTTKNQKAIHIPSHPTLSTSTCTNNIPFPLSKMHLFKLITTIAAAVSVSAIDIQKHFGQNCGGNFRVCRAIDPNRCCVGATAESVLFRYIPSNWRIETRGYDGGDCRNRRATILSAGATSVCMRSGGFLFTGAGYGFVNRKRAPQEAGEETCAVLEGEGQEQKCESSQEPDTLVLVDGSDFTIAADPNVTSAADIPDEFTPLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIM3</accession>
    <name>A0AAD8XIM3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_616171</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366338.1">
        <property type="nucleotide sequence ID" value="XM_060507954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIM3"/>
    <dbReference type="GeneID" id="85391853"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660:SF3">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47660">
        <property type="entry name" value="TRANSCRIPTION FACTOR WITH C2H2 AND ZN(2)-CYS(6) DNA BINDING DOMAIN (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="8"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="465" mass="52733" checksum="00E376F4453BD719" modified="2024-05-29" version="1">MPNFRRKSCQQCRSSKLACDRNQPRCSRCEQRNWPCCYSPMSQASVYLEKGYRQLRSPQLCTSGQISEVSLLDTTSIEAAIMTSTRDHNERQTASVFEVTDTIGDIGVFEWAAVPTNIANETPWTDDFTSNSPRLTSTGPTADMSPDIVTNIIADINTQISSRANFELGMLVDVNHLLRPRRNKTAEASLTSKMMLGSIRKYPAMLINDLNLPPFISSPCFGDEILCQQSGIHQCLPPPLAACASIVRMFPRDSLRDRSFAWKTIYMEQQRLFHEHESYDRKTLIAAVQAVTLYTILHIEDVASIPEHYLRSTTVTLGTMTYTMMKDRTGANYTQHHSISNRHEWISNESVGRLICFCYALNELLSIAICPSSGNGGATCKTVHLPSTRSLWLAKANIEWQRQYLEQLSQRDFKDTLKVSHLREYARYAGNALPREGWVADVENWCLDHDELGHFIWMATKLEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ04</accession>
    <name>A0AAD8XJ04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367028.1">
        <property type="nucleotide sequence ID" value="XM_060510340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ04"/>
    <dbReference type="GeneID" id="85394239"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="309" mass="34698" checksum="31F0C6F4EC340407" modified="2024-05-29" version="1">MHKSSPIQVNPPARQRPPAPAPGTQPRTRSQAQPTWPVEPLLALAIVARCMNLPSTPSLLRITPRILAFALQASGFSSFCHTTNCVRKGPSALPYKVGKPQFSRLRRPTLLSPPHLFLIWSNYLHHRRLLRLGPRAGPTELPEAEGGLRTLKASPDRVQGPFGNPQEPTTPLLQLLSFASARRGALQIDWETLAWLSLFHWSDRPAEHLCYHRLIILSPALLLQLAKSWVQLRPRLARRAPVSVRGSYLLQSNLERNFLDDYPIPVHTPYTVHRTPSSSHKPVLQRLQTQPPVHHQPTRDGVPGDHLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJX3</accession>
    <name>A0AAD8XJX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone chaperone domain CHZ-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_150745</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a heterotrimer with H2A.Z-H2B, stabilizing the association of the histone dimer. Also, with a lower affinity, forms a heterotrimer with H2A-H2B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CHZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368185.1">
        <property type="nucleotide sequence ID" value="XM_060501324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJX3"/>
    <dbReference type="GeneID" id="85385223"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019098">
        <property type="entry name" value="Histone_chaperone_domain_CHZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09649">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01082">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone" evidence="8">
        <location>
            <begin position="54"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="112" mass="12166" checksum="A1A4956EEF850911" modified="2024-05-29" version="1">MAAENENVAAGLAEETKGKGKAVAPEEPIEKSDAMDEDEDSSDEEEAPEAAEAVEEEDGMEEIDLNNIVEGGRRTRGRVIDFAKAAEENPAEEEDDEDDDDFAADESKMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKM2</accession>
    <name>A0AAD8XKM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_606603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369129.1">
        <property type="nucleotide sequence ID" value="XM_060507391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKM2"/>
    <dbReference type="GeneID" id="85391290"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="37750" checksum="1A34658862E878A2" modified="2024-05-29" version="1">MDQNVGRRLAPQDQVLASHMARLDLKKDQARSAHAAPAIATAAVRGSSGGSMSSRSSKGGLGRGGSTVRRASAANSHDNTLEAGPVDQLVCIDAEPSNTSTMARTSHGRGFEAMRMLAEQRGQVTHAPHEQVISRFAKEFYNLPSNYAGDPLNLRNQSTPVKDNENTALFITGLPANCDHTLLLKAVAGCAPVGKVYATVINAPKPIEGRLLTAAKLVFFSRAGAENCFRAIKQRRLIVGGLRPRVVWNRIKSAAQPNNSRSRVILIRGPSELVRRDVLDRWFSKKFSYQTEDVLERRVPQAGVTVLEWRFGSFRAQAEAATMFMCENELDGTKLEWRWGVDPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKU0</accession>
    <name>A0AAD8XKU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_568714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369297.1">
        <property type="nucleotide sequence ID" value="XM_060504112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKU0"/>
    <dbReference type="GeneID" id="85388011"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.245.10:FF:000006">
        <property type="entry name" value="Inosine-uridine preferring nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1729242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="48074" checksum="92605955A9FB2D00" modified="2024-05-29" version="1">MAPKNRVIIDSDPGIDDVMAMLLALSASPEELEVMMISVTYGNVPLQSCLKNVVALFHVLEKEIAWRKENGKPEGFESLKAYKPIVAVGAEHALEDDELAADYFHGLDGLHGVHEKHPHLSPDDRWQSLFHTEKNVDHDPSPFNQYFTPAKQVAHKEILRILKENEPNTISICVVGPMTNVALAAAEDPETFLRVKELCVMGGAVHVEGNITPHGEFNTVADAVAAARVFALTSPTPRSTMPPISDKKSSLPPYPARLSKKLKLTLFPLDITTPHLLRQNYFTETIKPIVASGSPLGQWVNHFMSKCFDKIIELEGDGQEPGLSLHDPLTVWYLLTQSDPKWKATAEPEDIRIETTGQWTRGMHVIDRRLRVKYNEAALEASETGDAVDVLTLAEVPGDTGGWLSTSRGNRVNRMVESPGEELFAPDLMKRIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL07</accession>
    <name>A0AAD8XL07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane proteins 14C-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_647987</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369398.1">
        <property type="nucleotide sequence ID" value="XM_060510137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL07"/>
    <dbReference type="GeneID" id="85394036"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF15">
        <property type="entry name" value="UPF0136 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03720)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="106" mass="11024" checksum="4F14394F747D57EE" modified="2024-05-29" version="1">MSSDLSVPSFALAVLTAGGGIAGYARTKSVPSIVAGVSVGLLYGLGGYRIQNREPYGVELSLLASAVLGGSAIPRAIRLRKPVPILLSVLSVFGLFTFGNEFRRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLI9</accession>
    <name>A0AAD8XLI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_568397</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369599.1">
        <property type="nucleotide sequence ID" value="XM_060504065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLI9"/>
    <dbReference type="GeneID" id="85387964"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000034">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF0">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="13">
        <location>
            <begin position="29"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="12">
        <location>
            <begin position="306"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1729544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="484" mass="53439" checksum="5BA22B2100737B4F" modified="2024-05-29" version="1">MASDPVLTMSASAQHAFTTDSSPEDPYIYQVGFGNRFSSEAIPGTLPRSCNVPQRVKYNLYSEQLNGSTFVASRTDIQNAWFYRIFPSVAHGDISKKPRNPDIESRFTSGNENIEFVPGGLCWRAFSLPKTDGPAIDFVQGLKTIVGNGDSTTKDGLAVHVYAANSSMKKRAFCSNDGDMLFVPQTGRLDIQTEFGRMMVRPGELAVIQSGIRFKVGLPDGPARGYIQEIFGSRYELPELGPLGSNGMALPRDFEFPVASFDMDTSEWEIVYKLAGKLWSCKQNHTPFDVVAWDGNYVPFKYAAEKFVNAAFVDKDQADPSLYTVLTAKSKMPGIPATDVMFFTPKWSSATNTFRPPYYHRNMSTEVVGIVYGGYKGTSRNLEAGGLSFQSSFMPHGETHEAFVQATTNELKAQRLGEGFLGFMFQISTHCAVTQYALERSGVLEVPPASLWDSMQGHFLDHAEEVNSDLRKRGLPTLGATLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM24</accession>
    <name>A0AAD8XM24_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Calcineurin regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein phosphatase 2B regulatory subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_747892</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Composed of a catalytic subunit (A) and a regulatory subunit (B).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the calcineurin regulatory subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369926.1">
        <property type="nucleotide sequence ID" value="XM_060513522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM24"/>
    <dbReference type="GeneID" id="85397420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050801">
        <property type="term" value="P:monoatomic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000047">
        <property type="entry name" value="Calcineurin subunit B type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="19728" checksum="52D28F12535E962A" modified="2024-05-29" version="1">MGNTTSTVLDNIVQGSNFDREEVDRLRKRFMKLDKDNSGTIERDEFLSLPQISSNPLATRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEQKLRFAFKVYDIDRDGYISNGELFIVLKMMVGSNLKDQQLQQIVDKTIMEADLDKDGKISFEEFTKMVENTDVSMSMTLDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN89</accession>
    <name>A0AAD8XN89_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_647184</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370486.1">
        <property type="nucleotide sequence ID" value="XM_060510052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN89"/>
    <dbReference type="GeneID" id="85393951"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="301"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1730431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="346" mass="39059" checksum="F04653EB384E7CE0" modified="2024-05-29" version="1">MAATQAPSSFYEQLPLPTLDRPFGIHLWPLLDKVWTPIVGYPVSEFRFQPGVTPMSTIKSAGIFVIIYYTIIFGGREWMRNREPYKLKGLFLAHNLILTLISAGLLALYIEELLPTVVRKGIFHSICHADGGWTQPLVVLYYMTYLTKYMELLDTVFLFLKKKPLTFLHCYHHGATALLCYTQLIGSTAVSWVPITLNLGVHVVMYWYYFQSARGVRIWWKEWVTRFQIIQFIIDLGFVYFASYTYFTSTYFPWMPNAGECAGEEFAAFAGIGILSSYLVLFISFYLATYKKGGKSQTRKSLRRMSQAPLPDPHAVASAVAGHSNGSAKASGAKANGSSTPRSRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNQ0</accession>
    <name>A0AAD8XNQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_342224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370890.1">
        <property type="nucleotide sequence ID" value="XM_060502463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNQ0"/>
    <dbReference type="GeneID" id="85386362"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="225" mass="24038" checksum="B38710928D500DA0" modified="2024-05-29" version="1">MEIEAASAKQSNWRNWRGSLRPASVWLGPTSSAHHWKRIVICRVYRARPAIRCPGIGNARRMRIGRCLFPIQCLIIIAIVLVVGSGGGKAASFTAFSPTEGGVPSARSWMNSDNATSQYLSALQALPGFGRSRSFAGTAREHGGLFYAEETEFPPMQSGARDSCCTCRAALNSKSRDVWGMAIGKTTMDQTNQIPCGPSSPTTQDGPGAYEANERASTGAPLGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPV9</accession>
    <name>A0AAD8XPV9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_540033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371547.1">
        <property type="nucleotide sequence ID" value="XM_060503393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPV9"/>
    <dbReference type="GeneID" id="85387292"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF47">
        <property type="entry name" value="ENDOCHITINASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042143805" evidence="1">
        <location>
            <begin position="20"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="33"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="52215" checksum="5AC6E30EC71E5E6C" modified="2024-05-29" version="1" fragment="single">MLFSKSFVAAAAAISPALAHSSSQTTTSASPLLGLNLYWGQYGQPTDRLSSYCDAPGVTSVSLSFVTYSPKNSAGYPGTNFAGHCGGEVYYKNPKTGEDTKLIMNCDYVKKDIQYCQAKGIKVLLAIGGYCPTGGPCSYDIDSEQDGHEFGDLLHKTFGPYDQGWNGPRPFDISETEHIAVDGFDFDLEFKYADQKPWIKMVEKLRSCGIYHISAAPQCPTSDTWFQLKELIYNAQFDSLFIQFYNNPGCQITDTPNYDDWETVISQTSKSKDAKLYIGVLASVESGWNGYAPPSTIKDLICKYQSKPHFGGVSIWDATRGAINQINGQSFHEAIADALKYGCNPIPAKTSTISISTSTSSVISSTSTSSVIVSTTSASSSSSSTTSSSSQSASASVSASASTSASTSTSVSVSASASASVSATGSASVSGSASASGSGSASASGSASASASASASSSASASASLTFFGNSSASATGSASSRIITTLSSNATATASASATKSATVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ55</accession>
    <name>A0AAD8XQ55_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371560.1">
        <property type="nucleotide sequence ID" value="XM_060513273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ55"/>
    <dbReference type="GeneID" id="85397171"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36297" checksum="34D91CDAECF78B2D" modified="2024-05-29" version="1">MVMLRLTAEQYRKLPILVDESSCVGKTYVITGGNSGLGLETARHLVASSAATVILAVRNLSAGETAKADIEKSTGRKGVVQVRHLDLSTYAAVQTFVKQISQELDRIDGFVCNAGIMIDQWETFEGVESSIFVNVVNTLFLGALMMPKLSESARKFSIKPTLVFIVSVLGYTVKAEMDKSRNGSVFDGLNDQKRANMDSRYALTKLVEEFTVRQFAAQFPVDRTGVVITMVAPGLCTTGLGRDARTFTKIMHEAVRAMMARTAEVGSRTILHGLVVGEEGHGKLLSGCKIKEFWVPDWVSNDEGQRLQKATWKELVTKLEQVQPGCISQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ72</accession>
    <name>A0AAD8XQ72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_646347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371446.1">
        <property type="nucleotide sequence ID" value="XM_060509956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ72"/>
    <dbReference type="GeneID" id="85393855"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="14747" checksum="9C02388382DA4B86" modified="2024-05-29" version="1">MGGKGGMVPYFRASFLGHTIGHASGVPTAGEMRLLVLASWVLGHAVVVLPVTSCNSAQSQPDAASTTPFPSIPFSPSAVLLHHLSSFAVMCPPAHASQRIHISGYKCRHKSDVDDITRAIPLDWTTWHSSRGLFPVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQI3</accession>
    <name>A0AAD8XQI3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MAGE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_597792</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371581.1">
        <property type="nucleotide sequence ID" value="XM_060506917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQI3"/>
    <dbReference type="GeneID" id="85390816"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="3">
        <location>
            <begin position="50"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="33598" checksum="85D07A476AB6D7BB" modified="2024-05-29" version="1">MPPSQRRRRPVDDSDSDEEPRHPRQRRNPEESAEEDGSEHGAVDAEASAEDQLAKKLVRYALACEFSRTPIRRDGIKERVLGDQGRAFRKVFDLAQQQLRLVWGMELRELAVREKFTMAEKRQALKSGSQAKTSSGVYVLSSTLPSEYRSPTILAPSKAPSTDAEASYVGFYTIIVTIIFLSGGELSEQKLRRHLNRLNAEANVAVEKTEDVLKRMQTQGYVVRKVQKNAGTQAQDGSEDITWLIGPRGLEEIGAEGAAGMVRSVWADQADAELEKKIGASFGISPAEDGDGDVDMSQAEAGPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQW3</accession>
    <name>A0AAD8XQW3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_4080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371829.1">
        <property type="nucleotide sequence ID" value="XM_060502890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQW3"/>
    <dbReference type="GeneID" id="85386789"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="25559" checksum="6326B0A68E91BA7B" modified="2024-05-29" version="1">MSRRQTHHLTEAPFANLSTLCPRLITALARLLVRANHLDPSDPVGCASSSLQDPGIRDRARISLLIVDGGAGLFTHHPSTLRRIRYDVNIADACGKLISRYQERKGTNYSPRGGMRSFPSPVSMSPPLPNAGLRLAGVSACFVVSLTPRPHHACSSTRVGANKQLCGLPTAQDSPSGMAFLCTTCRKLELCCNFGHRRASRGSSCALKSNPFAVAPVPRARDSEVILYSCEYNSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XRC3</accession>
    <name>A0AAD8XRC3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_10987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060372001.1">
        <property type="nucleotide sequence ID" value="XM_060501081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XRC3"/>
    <dbReference type="GeneID" id="85384980"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="24796" checksum="8492D5321A20488C" modified="2024-05-29" version="1">MLAYLREEFDKGSALTGEPFNIRYELGMFHRDLCQRLTMYHYHRLRSVGPITRQVVAARANSLWASNPSLRRFEQQHETVPWGVPVPFLTFRLLSFLPAPIEPGPGLERSWVSQFQIVCSPIARIAYVRIKPGRGYTVNGMTVEEAEWMIGGMRLLHVEMLSILGLCRHQPMFWSGEDLAAFAQDVFDGAAVKGRVHLDAISSAKEHWRLIREMEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZA1</accession>
    <name>A0AAD9CZA1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_569044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369273.1">
        <property type="nucleotide sequence ID" value="XM_060504143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZA1"/>
    <dbReference type="GeneID" id="85388042"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF2">
        <property type="entry name" value="F-BOX AND WD DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11400)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="127"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1179" mass="129125" checksum="87DECC7BFB79812C" modified="2024-05-29" version="1">MQHWPTESSETQHQQDNPPDITTSVQHGFCSRQQPNGVAVLRREETGSASPRSVPDGGRRDSFDAVSAAQLDEKLRRLSVDDSASVDSHSAVAGQRVIDYENAQTPSTPRQALGFKVIKRSDNRPDSVQLTDFPNELLTHVLSHLHPDSHSAIALVSKRFYSLVTTPHAWRMAFLRFFPGHDSLATKSGEQSCAGPLDHDSFEFVRSESRYFSRLTSLATWRSEYLLRTRLLRGLIRGKPGAKPGGIGASGRSSKKTSAVLTYNSKLPWAVTHIHADFTVKKAPRVIHGTADLGAATLSDSFIGKVEKWGFRDPFTILQLDEVFPNLEPYGAGDGPAACPNVMDVSQPYGMLSGEGFPGGRAYYRPINEMHGRYLGSDTGVIDTYPDIPKIPELSEAISAVWVAKSTAVPNITHSTVGIITGSTLGIVTTYALHGDGSGPRHPNGEMTTRWVLSPGVPIVSIKVDDQYTQKRKTAQRVWAVALNALGEVFYLVDVPKTSLERSKGEDVTKNAWFAGRSVYWRLIDDSRRQARPDEFDKHALRGAYSPRSPADAMNLSKEQLVAEAREIEKFLRYKPSHFRKVCDGWDMRRRLEVDFANDDGGGAGEVIVSIHCGLEETHPPSVTRYARAMSQTPRQTPDIVEDTASVEQDVPPIQQSIFGSGRDYKHASQPQPKPTKAVEKGDVTPISSGSLTPQAKLNSMDEWAVATMSLGNHGASEITASALDLSSHALLTLTEDPLQFGPRSAATPTMTPQTAESSTEIPGRRTRMLAIGTKDGSVVVWNCREQRSLSTISPLRIIQTESPEISCLALTALYLVHGGNDGLVQAWDPLASSLEPLRTLNGRSNGRVPRHMMTMNPALPIDTYSAARAIYLDPDPTVLRGITSFGAFLRYWSYSATHQPPGRKRRLRHADVHGRLATRRQGGNVSGYIAAETAELRREEEQDIKEEAWLRNRFGVGAFGDLTEEEALQYAEMISQETLLLEEQRRTSASDTGSAADANFDTVSSFSESTVDTVTPEPSITGFTPPPPVVEEEDEYEQQLQQALRLSLMEATDDMAESPRKNSSSDFEFAIKYKSKPAKKTTKRTPSISPPATYKPVAGAKAGSSSKATPKDDDLELALLLSSAGSASHPAPRDDDLELALRLSLQENGAGDFSGLGIQQEQEEFPMLETRGKGKGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D195</accession>
    <name>A0AAD9D195_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Porphobilinogen deaminase</fullName>
            <ecNumber evidence="5">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Hydroxymethylbilane synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_566809</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370488.1">
        <property type="nucleotide sequence ID" value="XM_060503890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D195"/>
    <dbReference type="GeneID" id="85387789"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13645">
        <property type="entry name" value="PBP2_HuPBGD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.40:FF:000002">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000005">
        <property type="entry name" value="Porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000086">
        <property type="entry name" value="Probable porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="13">
        <location>
            <begin position="11"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="14">
        <location>
            <begin position="242"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1730433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="37499" checksum="8AF6AAFA77935DBC" modified="2024-05-29" version="1">MAATPENGTPIHVGTRRSALAMKQTEIVVEGLSKARPDATFEIHSMQTLGDKDQITALYNFGGKGLWTNELEAKLVAKELDIIVHSLKDMPTTLPDGCTLGCVTKREDPRDVVVFKAGLAEQHGWKTLGDLPAGSVIGTSSIRRIAQLKRRHPGLKFADVRGNIETRLRKCDDPEGPFSAIILAAAGLLRMDYGARISQYLDSENGGTLHAVGQGALGIEARAGDERVLSVLRELEDEPTMLACVAERSVMRTLEGGCSVPIGVETSWVEVDGSKKLRLKATVVHVDGTQGVDAERTETIATREEADDFGKLVAQDLVDGGAQKILDDINQARPGDQIATAETAAAANAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1M1</accession>
    <name>A0AAD9D1M1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369906.1">
        <property type="nucleotide sequence ID" value="XM_060510068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1M1"/>
    <dbReference type="GeneID" id="85393967"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="206" mass="23171" checksum="99A092127DB3FC96" modified="2024-05-29" version="1">MGNCHGGRLMTKNGLVRLERPECAVYFFGLFTSVFVNTAEKSEYHTILDNIVVVFQLLDCLRQILPDYLPRPTSYNETPFVTRFDNLFPFSLSTVPLSTASYENPLSIVLLKPGTFTISLAPAREDKGSRPTLASRTLGDSWKERHSGPEQKRHTKRIVSRLEVVDRSLTSQAKPAVILSSSLLAVPFSLSRRSHARNRNPSYSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1T6</accession>
    <name>A0AAD9D1T6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_567311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the SSK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370250.1">
        <property type="nucleotide sequence ID" value="XM_060503941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1T6"/>
    <dbReference type="GeneID" id="85387840"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000146">
        <property type="entry name" value="Putative two-component response regulator SSK1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="492"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="665"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00093463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="690" mass="74627" checksum="1DFB192F8304D221" modified="2024-05-29" version="1">MPPAASQGRLASELTASNDLRPAATTTTTTTSSVAAPTALNNLPSIHEDQTPPGFDDPKQIPHLSQSHHPHQPLPPKFGAAPTVTLQAVSAEDLNDDQHDPLSHALGTPTPLATAILPSSPLSTRPEAPPRRQSLIPNRQTTLIRNLLEGRVENEARPASADSLLPNIANMVTRKVWVRRPGASATLITVNEDDLVDDVRDMILRKYANSLGRHFDSPDLTLRICPREQRQDRMLGPEEPVGRTLDAYFPGGQNVEEALVIDIPARRTPRPSPRAPTHATTIYYNDEGRPSEAGEGYFPPVANAAALPSPNLPVPVVAPVTVSAAHPAHPAHPIHPAHALTAHTQHSIAILGTGQVPPIPSPGGTRSRAYRERPERPRLGRTHTSSPTILNQVNAQSMAAAAAAAAHPTHSFHPRLPPSRTQSNTSEQSNAQPAAPPLPTPPAPEVQPARVATPPPRIASPRPASSRPKKKKTVDHPTLPAGILNGGVPPINVLIVEDNPINLKLLEAFVKRLKVRWKTAVNGRDAVTMWRTGGFHLVLMDIQLPIMSGLEATREIRRLERVNSIGVFSSSAGSAPEAPNGEPEEKDKLTNMELFKSPVIIVALTASSLQSDRHEALAAGCNDFLTKPVNFVWLERKVMEWGCMQALIDFDGWRRWKDFSQQNDEAEAKKSAALKTKAKKNRLSMTSVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D287</accession>
    <name>A0AAD9D287_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCA7, zinc-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_646161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371237.1">
        <property type="nucleotide sequence ID" value="XM_060509928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D287"/>
    <dbReference type="GeneID" id="85393827"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904802">
        <property type="term" value="P:RITS complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037804">
        <property type="entry name" value="SGF73"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805:SF1">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="224"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="45464" checksum="73E2AB05702271BE" modified="2024-05-29" version="1">MAAVSDSKKNDEQTIKVASKKDHKNKPDGPIKLKKPAPKYNKPGNWREGSIVEEDKKPKKDDSASISVASPGPVVNPLDDIAREAFATGRPLEDTPDLQQCKHCKKSILKTAAKTHIAACLKLKKEKAQRKKEAREARERAKEAAREEEARKADEDPDGKGDDDSDGDEDGGDGKKATGNKTAKKTGGKKTDGDTGKGKKRKADGDAEKGPKQKKKKEEPKPKAPKPKGPVDVERQCGVLLPNGQPCARSLTCKSHSMGAKRAVAGRSLPYDMLLAAYQKKNQAKQQKAALDANAPLEDEDEANAGPVDSDEETAAVMSALAHWNPQPVVPQPVLIPIKRQYQLARLHEQLQMATNGGRTNIFKVNGFGAQRLPQGHPGLNDTEDAPGELDDVNFGGARRSSSFSMQSHPQRRPSVTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2L2</accession>
    <name>A0AAD9D2L2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_600861</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370895.1">
        <property type="nucleotide sequence ID" value="XM_060507060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2L2"/>
    <dbReference type="GeneID" id="85390959"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000028">
        <property type="entry name" value="S9 family peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="479"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="699" mass="78198" checksum="BDBF6DA4121CED50" modified="2024-05-29" version="1">MMTIQASKFTPEVLLSAPRRSPGIPNPSGTKVLYTVSTYSFESHSKTSQTRVLDVESGHSSLLYEESSYSDVTWISDEEVLILRSGDKGATTILLGDVTKPSTVTEIRHFEGSLSSLKAKRLSEDEVAIAVAVLTTPEGAMYNPAAEKKQLTTGKVYSSLFVRHWDAWVSENQNSIWYGLLKKSDKSYKFEGQGLTNALEVTRLVSPVPPFGGSGDFDIGKHGIVFVARDPNISPAIYTKTDLYFLPLKTFAEDKPPLPQIVKTSKLRGYSAAPVFSRDGKKVAFTRMKSDQYETDKPRLLLVPDVFDLASVQEFYQTDDGAGGWDARPEWITWSKDDSELYVSAEEHGRAKLWKLPATPHEAKDLPAAIYEEGSVVEAKLLGDDGEKLFISTSSRVENSAYSVLDPVSQKTDLVSSSSKHGKSFGLSKSQCDEFWYKGAEGYDVHALVVKPSNFDENKKYPLAFLIHGGPQAAWMDSWSTRWNPAIFAEQGYIAVMPNPTGSTGYGQQHTDNIQNEWGGRPYVDLVKCFDHIEKNISYIDCGNAVALGASYGGYMINWTQGHELGRKFKALVCHDGVFSTLNQWSTEELFFPLHDFGGPLWENREGYEKWDPAHHLDQWSTPQLVIHNELDYRLPISEGLAMFNVLQARGVPSKLLMFPDENHWVLKPENSLVWHREVLGWINKYTGLDKSEDVAIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3L5</accession>
    <name>A0AAD9D3L5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_564053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371870.1">
        <property type="nucleotide sequence ID" value="XM_060503604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3L5"/>
    <dbReference type="GeneID" id="85387503"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24096" checksum="CC3B119E04358D94" modified="2024-05-29" version="1">MAVPPKFAAHKLTFGAEPEPSADGVPAQPHTIELYLDYVCPYSAKQFNTFYNAVVPAIRANPTWAANLEVVFRQQVQPWHPSSTLVHESAVAVVKVAPSKFWAYSDALFKAQKDYFDANVVNEPRNETYKRLAKLAGTVGVDEKAVLDLLVVSDKPDAEGALNVGNGVTNDFKVLIKLARLTGVHVSPTVLFDGYPNNEISSGWTLDQWKEWLQKNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6C0</accession>
    <name>A0AAD8U6C0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_758079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000200">
        <property type="protein sequence ID" value="KAK1708180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358212.1">
        <property type="nucleotide sequence ID" value="XM_060514981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6C0"/>
    <dbReference type="GeneID" id="85398879"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF6">
        <property type="entry name" value="SPECIFIC TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06130)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1708180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="661" mass="70960" checksum="FF9E1FF2C2C81FAE" modified="2024-05-29" version="1">MSNPAKGVKFVGSDSSGLPLKRKQVLQACESCRRKKKRCIHGEPPPLEPAHDGCAGSSPPDNAGSHVVAGSGSPSKHRHSASVTADAVLSTTPVRRESATAGHLEPAQTPQTRFVGDLNPEGMFAEAADSDPAANPTQKAEVGVWLPSLNAASAQSTTSVVSRPSAIIDKVLLPYVKQNCLTCVPPEKDYKHLHKVYRDKIHPIVGLIPDEALDDGDSPAGIVMRQVICLAAATDPDMKSHLRLASQGNKRLSYQDFSQTLSSSIRAILDTSLISDRTIHIRALCMLSLYAQPSGADEADLPAQLGARAAHHSQTLGLHLFHSSNDSLDTLFCAVWALDRINAATYGRPCVLHEGDIGPGLDDCFRRQAPCFQLFLSVVQWLDKVIELYRPGVIAQSLEAKPFIDLPVLEPMILEANALQVPTPLLATIEVFYHAVIILSCRLSRPGPPAQYASSVPPPSANARRSLAAERISSAIRRDHLSPVPLVPYALSLALSVEYRKMRHSALPMFRARARSAFKSNSELMKRFGDVFWSARVVAGLGERILREMERAANSIAQEGGAALPAATALVEVPTNGKLDEPLVVDGAPAEPPSAPLAPASTADLPALEAIDFSIVDAMPHLDVFGHFDPSFNLSAVDNALEANLDIGLPLNWGEWDQFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U705</accession>
    <name>A0AAD8U705_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_713849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000254">
        <property type="protein sequence ID" value="KAK1704903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357513.1">
        <property type="nucleotide sequence ID" value="XM_060511646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U705"/>
    <dbReference type="GeneID" id="85395544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050592">
        <property type="entry name" value="GDSL_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642">
        <property type="entry name" value="GDSL ESTERASE/LIPASE EXL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642:SF139">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160946" evidence="2">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="295" mass="31749" checksum="79E649A7FDB0DF69" modified="2024-05-29" version="1">MKSFTQALSLAAGLSLSFASPTPAVFPRQTNSSKNLIVFGDSYSTVGFWPGGTLPAAGNPLGNPSLPGQTTSSGLNWVGHLTSTLNTSTILTYDFAVTGATTDKDIVDTYAQYCVDDQVDQYKQYVSSVVNKDNALVAVWIGINDVGEPFWDKVSAPVTKIMDRYFELLQTLADDGLKNFVLLSVPPFSDQIPAMIGQSETDLTRLRSDITSYNAALETRLATFKSANSGVKGLVFDTKPSFDTVVENFAQYGAKDATCYGSSDCIWADNYHAGLAIHKLLAQNLVKGVAANFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U833</accession>
    <name>A0AAD8U833_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1295 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_193249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000229">
        <property type="protein sequence ID" value="KAK1706130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357778.1">
        <property type="nucleotide sequence ID" value="XM_060501609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U833"/>
    <dbReference type="GeneID" id="85385508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="40382" checksum="5946F018AE45017D" modified="2024-05-29" version="1">MALPAVKSLEECSEWAKVVEPFIPQLLELPGKIIASPQSLPQIYLETNPLVSGFAFSLLIAVLTLGVSEYHRNFSQIDRLWSLLPNWYVLHTAAWAYLNDEPWQRVALAGAATTLWSTRLTFNYWRKGGYERGSEDYRWEIVRAYVPAWVFFLFNVTFISFIQSILLFAFSAAPAYSLLLASRIEPDLAASDYSFFAILAGLVLSEYISDGQQWDYQTAKAAYKKGNGTAAAVPRGWAQADLERGFVTHGLWAFSRHPNFFAEQMVWFVLYQWSCYATKVLYSYTFAGSAFLVLLFQGSTWLTELITAGKYHEYAEYQSQVGMFMPKSLFPYKKPPPKVIRTSELAKRQSKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8M6</accession>
    <name>A0AAD8U8M6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000283">
        <property type="protein sequence ID" value="KAK1703429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357285.1">
        <property type="nucleotide sequence ID" value="XM_060512997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8M6"/>
    <dbReference type="GeneID" id="85396895"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042222309" evidence="1">
        <location>
            <begin position="19"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="12987" checksum="92B3A8149BC43E63" modified="2024-05-29" version="1">MKFSLVPVAIALFSTAYAAPSAPATENAELVARGNCPAAQDCACTAKFDKYANPKEYGSTVSARISGADRGLTTSDWRGANGYGSSSLCRVTVNRVCGNCRAWKTTTDKCGYYSLSEFSCVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U909</accession>
    <name>A0AAD8U909_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_758943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000291">
        <property type="protein sequence ID" value="KAK1703152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357232.1">
        <property type="nucleotide sequence ID" value="XM_060515114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U909"/>
    <dbReference type="GeneID" id="85399012"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="83"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1703152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="370" mass="41322" checksum="9B5A82D4CE144ED7" modified="2024-05-29" version="1">MPRGRPSSKLAKQDIPYDAISKIVAHTLDPDTALVTLTVLAKGSRLDVSEWDVQEHRPTLLCDYWANFPGKTRQDVLGIGELYHPFRLLRHRRVRGQWQVLVQWLGYTSEGEDLSWEPVAKMRADAPDVLTDYCGYVNDESVNAALLGPMARGDANGEEKGQSSETKPQVTTPAAARSSVKRKRDSLVEPSEMPSEKRRRSSRHESTPTTKAPLPRSSTSASKRRQSKIPHDDPQSLSTPRATVSIRKQSKIPTDDSKNAGAAPAPSQSLPRRKNTRETSIEPAASLDAERLSPADVPRTMLWFMDDFTVGDMQKVCRFIDEHCTGKLRLPLYSGGDWDGKAASGRWEDVFMVSPLGRLGRYDNEDEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9B0</accession>
    <name>A0AAD8U9B0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="7">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_637151</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359866.1">
        <property type="nucleotide sequence ID" value="XM_060509288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9B0"/>
    <dbReference type="GeneID" id="85393187"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000045">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.270:FF:000002">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054692">
        <property type="entry name" value="LeuA-like_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002991">
        <property type="entry name" value="PRK03739.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911:SF1">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22615">
        <property type="entry name" value="IPMS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="14">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1713813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="591" mass="65874" checksum="79B1F6301F599D21" modified="2024-05-29" version="1">MPMLKEPWKKYKPFPALNLPDRQWPSKTITKAPRWLSTDLRDGNQSLVDPMNGDEKWRYFKMLCDLGYKEIEVSFPSASQTDFDFTRRLIETPGAIPDDVYLQVLSPCREDLIRRTVESLKGAKNAIVHIYLATSECFRRVVFGFSEDESVELAVKCAKLVRSLTKDDPSQSGTNWQFEFSPETFSDTSPEFVVRICEAVKAAWEPTVEVPIIFNLPATVEMSTPNVYADQIEFFCRNVTEREKIAVSLHPHNDRGCAVAAAELAQMAGADRVEGCLFGNGERTGNVDLVTLGLNLYTQGVHPNVDFSDLNRVIDMVEVCNKIPVHPRAPYGGSLVVCAFSGSHQDAIKKGFQVRESTVKSNDEHWQIPYLPLDPTDIGRTYEAIIRVNSQSGKGGAAWIILRKLSLDLPRGLQVAFSKVVQDKADQLGRELLSDEITDLFESTYYLRDNPRFTIVDYSIAPDRSQSPAPPQPGKTQDTKNLKRVFEGVVSIDGKEYKLRGRGNGPISSLANALKSVGVTLDVEDYKEHAIGAGRDVKAATYIECTATGTKQKYWGIGIHEDVVQSSLTALLSAASNVSRVPFLSLHYSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9F6</accession>
    <name>A0AAD8U9F6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000237">
        <property type="protein sequence ID" value="KAK1705771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357675.1">
        <property type="nucleotide sequence ID" value="XM_060515050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9F6"/>
    <dbReference type="GeneID" id="85398948"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041970702" evidence="1">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="188" mass="19789" checksum="A53C6FF6FF6939C2" modified="2024-05-29" version="1">MKFFVAVSLVSGLFATAASAIDLHLEFAGGCSTSGGGYVCQGWNPNTCCSVNAGTYFASGSFRAIPRNWNIQARGHAGPNCGSIREQQDSAGRDYICLGNGPFGGLGYGFNNRKMIRGATLDARNGEETEGCAQPNVLYLADGTQYNYTAIAETGQATEELVSLVVAGASADDMPSFEAFKLDEKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9L3</accession>
    <name>A0AAD8U9L3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_594734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000252">
        <property type="protein sequence ID" value="KAK1705015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357517.1">
        <property type="nucleotide sequence ID" value="XM_060506729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9L3"/>
    <dbReference type="GeneID" id="85390628"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF4">
        <property type="entry name" value="PEPTIDASE M20 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="225"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1705015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="48908" checksum="BADF398D53E272C5" modified="2024-05-29" version="1">MDTSDDGFVLVSHADTHPTCTSASPCSLAPASSTSTSSSSPPPPFLDEISSIVTDLADALWPVNKTIHDNPELGYREFIAHDTLVAFMRTQPAWKVTPSAYGMKTAWVAVWESGKKGPVVSFNAEMDCLPGIGHACGHNLIATASLTAALATSTLLARHALPGKLILYGTPAEEGGGGKIALLKAGAYNPTTCPGSPNRAPDINLISHPGIVSSTALMRTSAYTSLRLEYFGREAHAAANPWLGINALDALVVAYTSISVLRQQTRPGDVIQCNISDGGARPNIIHAYAAANFVVRSDTQPRLSELLKKVQKCFAAGAEATGATWKVTFTGAYKDHVPNRVLGRSYTRYFNALLGSGGDGDGDNDAPIPTDEDVDEIRGRTMASTDQGDISYAMPSLSVGFAIPPGKGGQGPHNPEFAEAAGTRVAFERSLRVGKGLAGVAVDVLTRKGMVDEVKAAWRRDMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9W7</accession>
    <name>A0AAD8U9W7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_636164</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360151.1">
        <property type="nucleotide sequence ID" value="XM_060509236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9W7"/>
    <dbReference type="GeneID" id="85393135"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06428">
        <property type="entry name" value="M1P_guanylylT_A_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="11">
        <location>
            <begin position="313"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1715008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="443" mass="49097" checksum="543236F8FBBC8C5D" modified="2024-05-29" version="1">MSLQVPYRGKAPREGATKAVILVGGPSRGTRFRPLSLDVPKPLFEVAGHPIIWHNLAAIERVPGKEITEVLIIGYYDESVFRDFIKDASHEFPNLSIKYLREYEALGTAGGLYHFRDAILKGHPERLFVLNADVCCSFPLPEMLQLFHDKNAEAVILGTRVSNEAATNFGCIVSDAHTRRVLHYVEKPESQISNLINCGVYLFSTDAIFPSIKTAIKRRTDRPSRLVSYPSSENLENSFIITDDDEERKNEVIRLEQDILGDLADTKHFFVYETKDFWRQIKTAGSAVPANALYLQKAWQNGSKELAQPSSNIIPPVFIHPTATVDPTAKLGPNVSIGPRVHVGPGARIKESVVLEDSEIKHDSCVLYSIIGWGSRVGAWARVEGTPTPVGSHTTSIIKNGVKVQSITILGKDCGVGDEVRVQNCVCLPFKELKRDVSNEVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA14</accession>
    <name>A0AAD8UA14_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_769559</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000213">
        <property type="protein sequence ID" value="KAK1707317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358005.1">
        <property type="nucleotide sequence ID" value="XM_060515328.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399226"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd19542">
        <property type="entry name" value="CT_NRPS-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.30:FF:000002">
        <property type="entry name" value="Nonribosomal peptide synthase Pes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000015">
        <property type="entry name" value="Nonribosomal peptide synthase SidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000014">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF12">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE IVOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="12"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="2538"/>
            <end position="2611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1707317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="3071" mass="342192" checksum="8D1C3942792D9C59" modified="2024-05-29" version="1">MAAISAQEGRTQVIFDQLKTFVSSILTVPVEDIDDASSFVTLGGDSFKAVHLYQKCAEQGLGVRFQDLLHGPLREVASLASNNDAGCSSTQQLRQGDGKFPQMPLDYDFTKIFDELREKYDVGDDAVEDVYPCSPMQESMYIGQKMVSKRLYRTRGLFETQAEFDLGHFQTCWNDTLNRHQTLRTVYVETPDATSGRLLDAVVLKSKPEPMVMKDVEDLEEIRRQFANGNLGTVNADEERHQNQITIYLDVQDPGRVLFQMDLNHLTVDGSSLIIIVDELVKGLQGSRLPGQAPGYGRYIDYLQTQTDEDGALSYWIDYLDGTEPCYFPVMNDNHVGDAGSFHVSEMPLDVGLDDIRAFCQKHNATISNMLQAVWSLVLHTYTGDPDICFGYLSSGRSLPIPGVSQIVGPMMNLLVCRVGGIDNMSLEDLLHTIRDDFLNALPHQCFSIGKVQRILGTNETKLFNTIMTSYYSPFMSDASSSTFFKLISSHNASDFDIVLKVVYSDSDIRVRLAYSTTTLSSAMASNVSHTFSSILSRLIETEDAQAAVRSTTTISSWDMQQVTMWNSRIPAPPLGPRSTCVHHLIENQGRLQPNAPAIHSWDGNMTYEEFDEAASIVAQEILRRGIGPGAFIALCFEKSKWYSIALLGVLKSGNAFVPVDISNPETRRRDILQQLGISTEFGLVICSKQQAPFFRHLAKEVLQLDVNQVSLKKGHTIPLPRISPNSPAYIIFTSGSTGKPKGVIVEHRAYAYAAQAHSNGIHINSASRVLQFASYGFDTSMEDHLTTFAVGACLCVPCEDDRLSYPDLASFASASGANWAHLTPSFAEMFTPATLPTMRTMVLGGEAMTAKNIHNWACPPHTELIQVYGPSECSVTSTISPSISQDISPTNIGSAVPGCAAYVARPDDPGILQAVGAVGELLIEGPILARGYLGDSAQTSISFVEGLEWALGKRLYRTGDLVKYDSAGQLHFVGRRDGQSLTPDEFASLLPRMDDDSLEREGTEPEMRLRSIWSEALNVGEDEIRWNTSFYHLAADILRYRSIERLAKELVRAISPASAQTNMSEGPSEPQTFILSPIQKLHFQTSPKGDDLDQQTMVIEVTQTIDQQKLLLALGILLKAHPMLCAHFQCLHGEWTQHLPARSAISVVDYCRVRFHSRKQLDYVVECVSEAKRSIHLSNGPLVAVDLFESQGQTLLSMTIHHLVVDAVSWRILLRELESYLLFETPIADEATSFQHWTLEQHRFSSNLLPQNVLPPSAHAIGANLSFWGMADERNCFGDCISHIITLDSNISEQLVSVQDVSGRGAHNMLLASVVESFVEIFGRSPGLFSESHGREIFTPEVDPSNTVGWFTTLSPIIANGHDDILRDIREFRKHVPLNGFAYFASRFLSKAGEEAFEHHHPMEVTLNYLGAFQQFEKTDSLFKRCSHEMQEKISGLRQQQRADSSRYALISILASMKDNKLSLQVEWNSRMHHQHLLVDWLHQFELSLKAFAVSLMGEYQRLPPSPSEPLVASIGLQRKELNSILKLAQSRLGITPTEIESVLPCSPIQDSLMLSQLKSVNNQYCQHFLFKLSGSMPLSPDDLSAAWKQVIATHQILRTVFIEDESGRFLQVALKTVEAEIQVRTLQSESDLPTLWAEQSSSVAPKPLSGKILHKLQIYTANDGSVYCLLDKNHIITDGTTSRLLIRNFLAALNGRPHQDACPYSNYIDYVEQQNADEIAQYWRLYLDGAPSCLFPILRRHRASSFQTLEFTRTTATFPKSDLNSACRKLDLTSPIIFQAAWSVVLSTYLKSDDVVFGLLGHGRDIPIPGASEIVGPMANIVPVRVQLSSRTAMSKILTALQEDNIDHLTRQAVSLARIHHAARRSGDALFNTIFNFQKTTVALGQGRIKSELLFAHDISEYDIALCITENQGQFHINIETRTHFMSEVQAERILSVFLNAVRAIINDPETEISKMCLTSALDEKQMQEWNSSPLKTNGRCIQDMISETAQRQPSRPAICAWDGDLSYAEVDFLSTNLASRLQAMRIVPEDVVVLCFEKSLWAVVSMLAVAKSGAAFVHIDPNGAAKRNKSVVEQTGARVGLSSPKQSDKLTSLMETLIVVERTSIENFVNSAISLTRLVTPLNTLYIIFTSGTTGTPKGVMIQHKSFCSAVAYNTSWLQIKPESRVLQFTNFCFDASLEEIFTVLVAGGCICIPSEEERMSDIPGFVARRQVNWAAFTPSFLRTLDPDDLESVKFITVHAEPMGQDLVARWAGKIHMRPSYGPTECSVTSTIGAPFEVDTIATNIGWPVGCRAWVVHPDNHHILMPVGAVGELLLDGPIVGKGYLNDEIKTASAFIEPPSWTADTSLSLEDDRNTRRLYKTGDLVRYAEDGSLLIQRRKDHSQVKIRGQRVELGEIQYHLNNFSGIIAHSMVLVPELGNLKGRLVAVVSLTVLSSNLETRDYNQDIVMVKKDNLGQEMHQKLTDALNAITSALEKELPQYMIPETWLIVKSLPVQLSLKLDRQRVMKWVEQIDHQTLHDALDLHKVDGSDHECGSSTEETLRGIWAEVLGLEPHRVCLEQSFFRLGGDSIYAMQVMRLCKVAGLNVTTQDVLANPTIRLLANKIAKRAASPEASHALPRTTSNHAPMPHSVLAHDNVETVVPCSPFQKRMYQTFLSKPQRPYLFNSLVVLNAIRGSSSVDMNALREAWQQIISRHAVLRTVFIHDLASGSVFQRVLKEYKADIEVLAVNSEEDATREARLHLNAVRSKLFRDSSSPVSVRLFVGRNGETFIHFVMGHILIDHVSLAHVFSDFAALYRGQSPGAKPLTGFHDYIEHINTQRDFHASSNYWVDKLQGVKPYMVPIETMVGSGSDPHTMGSINFAVNITAELKQFLREAGVTLSNVLQFAWAMLLHVYTGHSTVCFGHLVSDRDIDLPHADEVVGPMLSMMIACATFDDTTMMIQALQSFQDDNIRSLEHKTFDLTEVERQLGCEGTGLFNTLVNYRKVKYSDDDVDIGFRSIWKQDPHEQLLVLAFNEEPLRLDATLTYYESLFSETTMKTLTQTYRRLLDLLIGHQSQTVGDIKAALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAA4</accession>
    <name>A0AAD8UAA4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_724514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000204">
        <property type="protein sequence ID" value="KAK1707762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358140.1">
        <property type="nucleotide sequence ID" value="XM_060512666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAA4"/>
    <dbReference type="GeneID" id="85396564"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="734" mass="83871" checksum="8A60E521522E4A8C" modified="2024-05-29" version="1">MSRTTDAEELAKPEKERERAVAAERERQQERERADRERERADTAEQQTQHTSLDEYIAACHSLVFANFTVETDRRLTSRGSITNPRNKLCPTILRPWSDFLHQQSIVFGTLYDTFPADRRCFETPSFLSGLGSRIAKRKITDEKALEYFLHNSVEDPVRAILDELRKVEAVKTVFDLGNGIVFENHPHALSDVAPEVVERNLPSTPPSTPHDHKVDLQQLRADQICVYRTEDVDGDSSTRSMLYVSEYKPPHKLTTPHLRLGLRSINIHQEIINRKTIPTSVDLNARFQYYAERLTITAITQTYYYIIKSGLKHGLLTTGEAIREPGTLLYYLAEPSAEVEAHPKHAHLYTAVTQYLAFTLSMPSERRLHSQEERHRAINKLKMWGEDFETTLRSIPDEERHPPDSSPGYEPKAYKNVDRSPYLLRGKRRGLMRDGRTTEQMRRDPNESSDEEPRRDVPDTPTPTERRARGKDSQSQAGQGSQAKRRSKRVLARRPRGDEDGGESHFKHTPYCTQKCLLGLVGGGVTDSACPNKLLHCRKPANDRGHCLGRQRANAQHPIDRTEFLRLLQEQLERSLDYGIVSLRQSGARGVLFKVSLLAYGYTFVSKGTREAAFYKRLRGVYVPVFLGSIDLRTINRTYFYDHRVYIVHMSFLSWGGQDLYEMKRTDCGVEDLEAMKTRSLNEIRALGHHADRLRKGAVCEARSPPTRATCAEQAQTDEEGSKGQRLSSEVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAP9</accession>
    <name>A0AAD8UAP9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_767990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000193">
        <property type="protein sequence ID" value="KAK1708667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358349.1">
        <property type="nucleotide sequence ID" value="XM_060515300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAP9"/>
    <dbReference type="GeneID" id="85399198"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041951852" description="Lysine-specific metallo-endopeptidase domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1708667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="32956" checksum="1FC1BE72A2F21D8D" modified="2024-05-29" version="1" fragment="single">MSASSNLRFRILWGLLLTCRLNSGAAAVINTNDQNLAQRDSTNTYDNAYYVVQGSWKCDFTQLRLLDAAINEAEELAQKTIDVLQVKGAETSISYDTWFGSSNANPTTKDTIINQHYKTVLSHLPYPNIPAAFRWTTHAEFKAPLNEAPPTDDSIVYGCRQMCQDGVLASNLRATGMKSDGTTKEFGPLVLVLCPAFFELKNNNAEMIKEWQRTLGFGSGNSKGRILVHEVQHMAKGTSPSEPAEDLSEPLPDIFGHDTCYSPSCCARLSDTDKMRNAQNFALFTIDVLAFPNAGAPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAY1</accession>
    <name>A0AAD8UAY1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">37S ribosomal protein S25, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_634132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360777.1">
        <property type="nucleotide sequence ID" value="XM_060509076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAY1"/>
    <dbReference type="GeneID" id="85392975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23701">
        <property type="entry name" value="At1g26750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059242">
        <property type="entry name" value="mS23_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016939">
        <property type="entry name" value="Ribosomal_mS23_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37799:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13741">
        <property type="entry name" value="MRP-S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="237" mass="27960" checksum="BC92FDDDFC0EEC54" modified="2024-05-29" version="1">MGRQIRPARIYQTVSQELNSKILPQYPVYEPPWFQVMRDIPPSEIITRPAIVNTQNSNRKNRKPQGIYKPQQIVHEEDSLRKTFFRDHPWELARPRMILETDGKDYQRCDWSKGVRQYRTPLTGECVVQRQLWLMHNKKYPRAKAYDIARKEFYALRQEEEIEKRVAREEARHVGAYFGKNRLQIAQDLEDKEFEVWKGWASNRAVMIEQARTASYANFGEETTDEAAAEAEAEAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBD5</accession>
    <name>A0AAD8UBD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_709251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359897.1">
        <property type="nucleotide sequence ID" value="XM_060511568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBD5"/>
    <dbReference type="GeneID" id="85395466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="9"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="484" mass="53302" checksum="45DE396DF2703A77" modified="2024-05-29" version="1">MGRLTTVLSAVFLAIGGFLFGYDSGIITSTIALDSFGKYFRHPSDTVAGGIVSAFQGGAIFGTIINMLFANKIGRRNTIFVGSVISCLGSALQAGAVNMVMLIIGRFIGGAAVGMVTSTIPMYASELSEAKYRGILSGLLQWMLSWGFLIAQWLGYGCSFVKSDFSWRFPLAFQAVPGVILVTGIYFLQESPRWLMERDRHEDARRSLGKLRSGLDEETIDLEFREIRDVILADRALGNISWKSIITKPSWRKRLLLGCGVQAFGPLSGINVINYYGPRIYKILGIDTQTSLMIIGISGALSIVYCSIGLWLLDRVGRVKPLIVSAAGLGAALLVNAVQAQYLNENNANQLRSMVAMNFVFSMFYTPLGIISWVYPAEIFPVEVRALGNAITTFTNWTVNLIFAQISPEALTNIGFRYFYVFFVFNLIAMICYIFFFPETKGRTLEQMDELFGDQLVPHAMQDSVGAAAAVAKDEKLVEQLDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBR2</accession>
    <name>A0AAD8UBR2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_591335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358844.1">
        <property type="nucleotide sequence ID" value="XM_060506425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBR2"/>
    <dbReference type="GeneID" id="85390324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="714"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="743"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="4"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1710565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="778" mass="84853" checksum="5259FF96CA1F3BC5" modified="2024-05-29" version="1">MGFKVIIVGGSVSGLSLANMLERLDIDYTLLEAYPNIAPQVGASIGLLPNGFRILDQLECFEPILEMVGEYHLRNSLRGPDGKPLGPPSLVNIQHLEARLGYPSIFIDRQMLLQVLYDNLKNKDKVIPEKRVEKVELLEEGVHVHTKDGSVYEGDIVVGADGIHSTVREEMWRIGHDERPGYFPLDEHSRVPVATKCIFGISKRPSNLPIHNQQMVFNEGRSYLIISAPGNRTYWFLFSGVGDTKYGKDIPRYSKEDTEKLALEHWEDLVFENVTFGDIYKNKIMATLVPLEEYVFEKWHYQRIVCIGDASHKIDPISGQGGNGAMEAAALLTNALTEMLEKNPKAQSTEIVEAALAQVHINRHERAKTLVANAHTLQQVLTGRSPYSKIVTKYLVPILGDEGFLGTAVPICKASHRVYRLPLPQRRRLVPFDDELPARPMTSQASQAASRMALVLASGSIVALLYYSGGIDHLSELKESVRLVMSESWDLGLAQGASSLTKTSSLGSLVEQIQFKTSLFSALVVWLAEGHRFGNRLSVLLWPSLSAAALTVFGPKAFMPLLGLGVVTQGTNTLPGRHVPVKYAKAILPSAIVGYAIPTILASLPIQDLQLQQTICLVASAAPIFSAALLNGIASIIQKVKDVTSSTKAKEDVKVEDEEDFVDMYDKRDVVPLKMAYAFAVGVCATVHVASVVYPILSTTSSSNLADGSQTSTSIFGLASAALSLYSAWNLRSEGFVTTKQALLGSLGSIASGFAVGPGAALASFYYWRESVLDGLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC14</accession>
    <name>A0AAD8UC14_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_561831</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361392.1">
        <property type="nucleotide sequence ID" value="XM_060503569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC14"/>
    <dbReference type="GeneID" id="85387468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041898746" evidence="6">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1719308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="36860" checksum="8CE0E84664BEC881" modified="2024-05-29" version="1" fragment="single">MYSKLITALAAVGAGVASAQSTNICSSATVTVTDAAMATALPCTTFTGSVKISEDITGNIDINGPKTIKGDLIVTNVTQLVGLTSSTLASVEGTFQMQGLTLLSDLRFTSLATVGSINWVTLPALGSLVFGTAGVTKVNDILISDTFLKSLDGLNVASVDSLRINNNNQLVSYSNQLANATKTIEINSNGPDLGITLPNLIWAGEIIIADAAKVQMDSLEVVNGSIKFDKNTFTEFIAPNLTQTTDGDVSFINNVELTNLSLPLLAKTGGGLTIQNNTLLQKIDGLPKLKQIGGAVLLRGNFTEVDLPALEDVKGAFDTQSTGNIDTSCDVFNKMEGRQIQGDYKCRSNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCH7</accession>
    <name>A0AAD8UCH7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_584894</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361662.1">
        <property type="nucleotide sequence ID" value="XM_060505804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCH7"/>
    <dbReference type="GeneID" id="85389703"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02666">
        <property type="entry name" value="Peptidase_C19J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025305">
        <property type="entry name" value="UCH_repeat_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13446">
        <property type="entry name" value="RPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="579"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="707"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1215" mass="136247" checksum="BE2CFE2DD18464ED" modified="2024-05-29" version="1">MSPSDSPTTQHWEGSPAPVKENMVGKTGRLAPRWIQDLLNSDLDSGSFARIEWDQQARCSKAGVPHRLVLVGNQSTSDTRNPGVLSCVCAICDFHFLIRTCWDPDQLVCLCRPNALHFPPKDTDFYLHHLVNIKQPVRPTKSTSNYHPLIRETILAVEHFACSAPRCTLQVTVEISRPRLKREWLHLLLNEQRILDNLANARKQSPDRFADARDDWCTSAPVTLNTYLRDLLDRPNPRNISQRNKRFQVVFGEECYAIFRAIMFTEENLDKDGVLEPYFIPPTLEPGTPGIPTELSALRAFVEDMQAETESVIIRGGKTGENRPYVGNRLFKELQCLDYPQNKIAQTATEAHRILGVLPDFDKALIFFAYTRQSALCEKRRPTFVEALKDIALLTNDDDFQTRAIQELTIMDGMPAPDSVGAGDELQTQAYSFFSLKYTASDDNVVSAFNTKIEHSPSQADSAREMLQIIGRHRNSDRILTHANGPMDVASAYRILEVDPQWPDSTIVMMSSVKLNKDPKSKATEEVAIKAMEAIAEDRNSDEIREAARTLSLLAQAPDQSAQAVEMDARPSNAANLPVGLENIGNTCYLNSILQYLNTVIPIKDLLAHYPDYELGLDDSHIQRRLVGGNKLKIDRAEAVVARAFVDELSKLLDNLSGSQASAIRPSQRLANAVLLPTSNLTEDPTKQASKTAEGPKTLEVMGTQFPAPPPLPARPAPGPPTNTAEHVEDVDMVNVTVDPISESASSVSSQTLVNLSDVDHEKKDWVPEDKTDIRIVSQPVEESSARPANDNDVRMTGVETTVLNVEQRVLKALETQTRDSGTDQQDVEEVMGSIINRLQAAIKPTRVDATDEVQWEPIMDTFYVELTNHTKFPNQDKYKSDSTLERAITAYPAEGGPTNIHDGLSRNFDLQRVAAGEADIMRYTSIKKLPPILHVLIQRTKGDGHKNMNPVEVFETLYLDRYMDTPDDPQFFKLRQKGWALQQRLDQLNNMPKIAAEDTQLIDSFTRDFVHVDKPDVEETSSLLNDMPTSSLSFAGQEPTFPTYPSQSETAFEKVDPPEPTGFTVEGRQQISNMREDELKSHKAELDQLFAQHKKHAYRLHAVICHSGQLRAGHYWVWIHDFEAGVWRKYNDRVVTENADTREVMKTLNSNGDPYYLCYVEEGKEGDLVKVPKRQQANPDSAAQDGDRDVDGDIELVDVENKWPQGSGILSLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCI9</accession>
    <name>A0AAD8UCI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_797505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000196">
        <property type="protein sequence ID" value="KAK1708402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358280.1">
        <property type="nucleotide sequence ID" value="XM_060515898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCI9"/>
    <dbReference type="GeneID" id="85399796"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="41412" checksum="64BB0446FDB1D674" modified="2024-05-29" version="1">MRELSEREFPITFYTSVSFALFKTYGIPTISKLLVATSQLSGDRTASKRRTDTGVLMYEIIYNTPDSRRNIDAISRVNFLHSRWREAGKISNDDMLYTLSLFVLEPMRWTALYEWRDLTMFEKNALAIFWKDLGNEMGISYDCLVPHMSQKHDALAWLEALQKWCLEYQEHNMVHAISNEKLAHANITLLLMDFPKFTHNFVFRQLRCLMEPVLRRAMGYEDPSKLDFFIFENLVAFRRNVLKYFCLPRPKWWTNPMIQDVDEKTGRMYLPSYLAHPYYVKPGFWWRWGPSALYTRLIGGHLPGDEGSKYHPDGYTIPEVGPDAQRCKGKEYMERTRERISQARGCPMAFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDS5</accession>
    <name>A0AAD8UDS5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_723412</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359718.1">
        <property type="nucleotide sequence ID" value="XM_060512558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDS5"/>
    <dbReference type="GeneID" id="85396456"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041933257" evidence="5">
        <location>
            <begin position="22"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="63"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1713392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="499" mass="54053" checksum="CDC22CCD5BF5DB28" modified="2024-05-29" version="1">MQIFYLVVAFILAATAIESAAVERSEFKCCLALLKDDVLSGKVLTPCNEDFHHRLESYYSANAAEPPRCMVLPQTAEDVARTIQIISARNCSFGMRIGAHSAFRGSNGLKDGITVDFGYMNSTEYDPTTGIASVRPGSNWGDVYSALDPFGVTAVGGRASVVGVGGFTTGGGYSFHSNRRGFACDNVVNFEVVLANGTIVNANAHENAGLWRALKGGSGNFGFVTRVDVEVVRSTQIWGGITTYDLSKTGDVVNAYVNFVNNMDEDPASQAIVTLLYGQQGLSLVAVLTNSDAKSSAPAFREFASIANVSSTARVGSVAEMVPEFTGPTPLGLYANWRTGMTSHSAAFMDFVLRTVPEYTKRMQLAAPASDFELLTQFQPVTKSMVAHGDERGGNVLGLGRVVADGSALMWLLALTVDTAKNQELILPLLLDLERVINQFAVEKGLQEDWEFLNYSGFDQTPISHYGEETVHFMRNISLEYDPGRVFQDLRKTGFQIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF44</accession>
    <name>A0AAD8UF44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_42921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360569.1">
        <property type="nucleotide sequence ID" value="XM_060503037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF44"/>
    <dbReference type="GeneID" id="85386936"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="371" mass="40894" checksum="F7E082C86C217481" modified="2024-05-29" version="1">MLTSREGFTVDVIARWLRKSVLNPYLSIPLATGLAVVSARKNGTVGLSDIRFDTAQRVAFLAALASFVLSTTEYLNKWSANNWTTDHTWDFDKEIIVVTGGSSGIGHSIIKHILARNPRANIVVVDLAPLLWEPPKGSNIHFFKCDLTDTKALKTLCTLIRTQVGDPTVLINNAGIARGYSIMEGSYADVELTIKTNLLAPFLLTKEFLPYMVRTNHGHIVNVGSMSSVVPPVRIADYSATKAGLTAMHESLQLELKYIHKAPKVRQTLGIFGFIRTPLVPFDPGQPHFMMPLLHVDSVGEAIVDSLYSGFGRTIYLPGIMSSVTALRAGPEWLWRLARETTASAKDIAYTPRQKIDDTTGQFEMVEPAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFN0</accession>
    <name>A0AAD8UFN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_40583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360651.1">
        <property type="nucleotide sequence ID" value="XM_060502873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFN0"/>
    <dbReference type="GeneID" id="85386772"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="14405" checksum="831B6B8E8A3167B0" modified="2024-05-29" version="1">MDRWFWWWSLLALVPILERGAGFARFAVWFPRWVCKHDWTVKQPGKRCGKRSSFALFSVVRVVWVSCVEVVRSILPFQVLSYPPVSPIMTPVLTSHCRSVVWVVLFFFFPFLNCSGDRRLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG79</accession>
    <name>A0AAD8UG79_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amine oxidase</fullName>
            <ecNumber evidence="10">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_633352</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a D-alpha-amino acid + O2 + H2O = a 2-oxocarboxylate + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="EC" id="1.4.3.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:21817"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361008.1">
        <property type="nucleotide sequence ID" value="XM_060509030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG79"/>
    <dbReference type="GeneID" id="85392929"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.9.10:FF:000018">
        <property type="entry name" value="D-amino acid oxidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="11">
        <location>
            <begin position="5"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1718008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="376" mass="40917" checksum="D969C0C09AC5E91B" modified="2024-05-29" version="1">MTNNVVVLGAGVSGLTAALLLSKSKSNSITVISKHMPGDYDIEYTSPWAGANMLPMAPEFDSRWERRTWPELNRLAAEVPEAGIHFQKSRVFRRKKDIEAGGNPYDALYAVDPWYRNVLPDYRELAKDELPPNAYSGSEFTSVCINTALYLPYLVGQCRKNGVVFKRGDVAHVNELTALHHSGKPADIIVNSAGLLACKLGGVEDKKVIPARGQVVVVRNEVEPMATISGTDDGPTEVCYMMTRAAGGGTILGGTYDKGNWDANPDPNIAIRIMKRCVELCPSLTGGKGIEALSIIRHGVGLRPYREGGLRLEIDKTTLADGTPIVHHYGHAGWGYQGSYGTAEGVVELVNKIRAEKGENLAAEPKLFSWDRPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHD3</accession>
    <name>A0AAD8UHD3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional activator of proteases prtT</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Zn(2)-C6 zinc finger-containing protein prtT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_753072</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the prtT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364006.1">
        <property type="nucleotide sequence ID" value="XM_060514296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHD3"/>
    <dbReference type="GeneID" id="85398194"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF34">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR OF PROTEASES PRTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="12">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="99"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="623"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="583"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="637"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1723951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="681" mass="75600" checksum="E16922EC559F079C" modified="2024-05-29" version="1">MEESSRKRKRRILSCDTCRRQKCRCELDEDSEACARCRSLRITCTWNDSGDTHSVSSREAPAKLDVEGRFRSLEASIVDLKATVQALASGSRPEVRRALATGRQERLHQQQQQQSLADKSFVDDHDSQKARENEDVEPGDRHVYLSPAEVVRKVGSQLSGGYRRTFDVQADVVSSGILDDKTARDLVGEFVSRRRNTLLINSEADLAPKNRDLRHASPFLHDACCLHAMRFSEHSSSVLHRRVFEHVRLQMGQLMIASPLPLEELTGIMIMALWASAPSQGPEYIDSWLVSGHCAQQAMLSINFSEVLSRTKSRTSTDEDQRVMRLWANTCLVNLHWAATTSRPATVPTAYLLQCKLLLNFEKPTMLDAMVYAEIMLYMILQDKFAQRSYLGSDGTCEELSTWKTRWNYLFDLPAASTLRISYSIAWLILARRSLEHDLATSDQDSLSSSPRLAPADARTDRRHRNADPQSLPDMTQSRVRAFATDVVRAFVDMPGSRAEELPEFHRLCVAYAMLIISKYEPRSSLLEGDGVGTGVVEGDDAVLELLRAAQRHNGVRGNSAPSAIQFGLERALKKVAERTEARAGSTAGTTTGSDGHGLPEVGVSFIRSGSLRGPSAVAAAATATPTWTHHQDNVRGQHNHNPSSFTGATLVPEFDESLSLETMDIFFSGGHLGLGDHSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHJ2</accession>
    <name>A0AAD8UHJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_722624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360830.1">
        <property type="nucleotide sequence ID" value="XM_060512487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHJ2"/>
    <dbReference type="SMR" id="A0AAD8UHJ2"/>
    <dbReference type="GeneID" id="85396385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1717343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="44209" checksum="73109044C2101164" modified="2024-05-29" version="1">MAAEAPIVLDGGTGFLKVGYAAQNFPEFQYPSIVGRPILRTEEKGEDNDLVIKDIMCGDEAAAARTMLQISYPMENGIVKKWDDMQHLWDYTFFEKMKVDPRGRKILLTEPPMNPLRNREQMCEVMFDRYGFGGVYVAIQAVLALYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLTRRLDVAGRDVTRNLIALLLRRGYALNRTADFETVRQIKEKLCYVSYDLELDKRLSEDTTVLVESYTLPDGRVIRVGSERFEAPECMFQPHLVDCEQPGIAEFLFNTIQAADVDVRSSLYKAIVLSGGSSMYPGLPSRLEKELKQLWLTRVLGGNPERLNKFKVRIEDPPRRRHMVFLGGAVLANIMADKEGMWVTKEEWDEQGPRVLEKLGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHN8</accession>
    <name>A0AAD8UHN8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_586572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360905.1">
        <property type="nucleotide sequence ID" value="XM_060505964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHN8"/>
    <dbReference type="GeneID" id="85389863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="42"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="715" mass="81089" checksum="5A7EBF0B1038DD28" modified="2024-05-29" version="1">MSTFTYDEKLALDEIRLIQLLPGEWLDGLECRLYLAQQEHKYQALSYTWGSSKRSNQITVNGKIHRITFNLDRALRSVRGQTKAITLWVDSICIDQNDAAEKSHQVGLMHSIFRNATEVIAYLGDGLDRSRRDYARRFEKLGKSPLINFGSLSEASLAGVQGLWDKWKDSPPESLTEHEEIICLYGLLMELSGSLQYHMFPGKQSPEQNGMWLDLSEAHRRVLSERMRHFATSDWWNRMWIVQEACVARQLTVVCGRASIPFLCIGHAAQALLHSPVTKHSDLAKVMIFVAGKIDAINTLRLGFGSLTHFTTSNSLLWLLRRFRSRKSSEPRDKIFALLRLAEDLKRTKPFRDNHLCITVDYGIDVGEVFSDAAYDIVRDTGLLWMTTTDLLAKTRIDIPSWVPDWSSEHMVPGFNQRRYRLQEETLLHFNASRLRFCHSQLHSSNDQPRYALPQQHFEELLKGDDRDRWKPVHCLPSMIKYTSSPPFQKDRQRSALILQGVTCGVVASASVVILSDLSNIGLAILQVRESYGGHGGWQIGQRSFFETVVTCLSSSHIRTLVPQAAAFRLVALPKDHDLRAPSNLHVPPWIEDTVRTMAAGNRLFVTNRGQVGLGPESMHVGDSLCVLEGGLVPYILRKHAGTIYTESSMVHQTESIMGTHRFTMVGSCYADGIMHWGDEEHGWGDNADDIERLESKLRRKLKAPELVETAFLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ38</accession>
    <name>A0AAD8UJ38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_794355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362523.1">
        <property type="nucleotide sequence ID" value="XM_060515812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ38"/>
    <dbReference type="GeneID" id="85399710"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="20638" checksum="E91C0A2547B4D34A" modified="2024-05-29" version="1">MRRRPRENALCQKSRTKSRRPLAYRIPRFSTPTPTSQHPTTKNHQTHRPLTHPSSQKTTHQTSQLLPQNIMAKAKKEKLAINSYTLNLPSNSTSSPQHHSLIPKPYLTLPSILNIIPLQPFITSTPLTALTSPAYSDPISDLYSGAHTLQLLAYLIAHVLVSSIIYFLTSPECHAVPPRLQLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJH1</accession>
    <name>A0AAD8UJH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_582006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362925.1">
        <property type="nucleotide sequence ID" value="XM_060505512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJH1"/>
    <dbReference type="GeneID" id="85389411"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="23"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="402" mass="43828" checksum="9FC0A6C6A83EBFC9" modified="2024-05-29" version="1">MASTFSVEKARAQFPALAKNQIFGDNAGGSQVLGTVAKSISEYLVNNNVQLGASYKTSKISTETFDRAYKVAADYVNADVGEIVIAPSTTQAFRNLAAALKLKAGDEVILSEVDHESNIDPWLHYATLAGATVKWWAPPDHSNPKLDVAALRNLLTPKTRFVACTHASNILGSIHDIKAFADIVHAVPGALLCVDGVAYAPHRAIDVKEIGADFYAFSWYKVYGPHISLLYGSFKAQEQLQSLGHYFNPSGTLMDKLELAAASYELTQAVMPLVAYFGDNPKQTWAQIAQHEQVLQKHLLEFLKSRPDVSIRGDVSSAASTRVPTVSFTVKGKSSRSVVEGVEAQSIAGIRWGHFFSKRLAEKILGLGEDGVVRVSLVHYNTGELRSSTFWMIQRADVSSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJH7</accession>
    <name>A0AAD8UJH7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prenylated rab acceptor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_651622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365086.1">
        <property type="nucleotide sequence ID" value="XM_060510463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJH7"/>
    <dbReference type="GeneID" id="85394362"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="25622" checksum="A0CB37CBC204240E" modified="2024-05-29" version="1">MGFFDLSTGSVISGRSSHSRRHSSHHSKKHSSKHRSRSRSSSRSRSKRHSAPSIAASIFGGDDYKKNNASRGSFFGIPNASRSSFFGFGGGRPSYYKRSPRNGFVQKTLKQVKRLWRDLVYYAKKHPYKVVALVIMPLITGGFLTALLARFGLRLPPGIERMIGIGAKAASGDSMGLVGEAVRMASGGFGGGAATRAHVERGYDGDYSWERRSVERDGGGGGGWADGLMNGVAKMFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKQ1</accession>
    <name>A0AAD8UKQ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_348610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364667.1">
        <property type="nucleotide sequence ID" value="XM_060502505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKQ1"/>
    <dbReference type="GeneID" id="85386404"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="197" mass="22447" checksum="AEE39A52C2B1E350" modified="2024-05-29" version="1">MFTFLGREFDLYVGIIWWSFGAVLGCTIFGALMRGVSNKTLFVLLGLAGLFDVVLEECLLNYGGLYLYYGHQPLVLFSLFPCWWAFCNVSAVFLGISMTYRYREWFNGWRSIFVLPILPFCYVAGWSLAAMPTVYAVHADYSPVVTQLCGILTCCLALLQIGVIMDVVLRRQVFETDHTSGRVVRFKEKAWSVKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL88</accession>
    <name>A0AAD8UL88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_792514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364952.1">
        <property type="nucleotide sequence ID" value="XM_060515763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL88"/>
    <dbReference type="GeneID" id="85399661"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104411" evidence="1">
        <location>
            <begin position="22"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="225" mass="23434" checksum="1A70DDD18DCDE305" modified="2024-05-29" version="1">MKGPSKAIGGVLATLIGLTQANSDIVSLFTNGAAYIQEASATLVLPKLPSSVSGDVAIWSAVMMENQASFLQGVTSNSPSGSYCNDGGKSWCNFAYTLVGSNPTVGDPVTASSGSTIRTHYKLNSATNLWDQDVYIDNKLASSVSTSKGQKGNIFYISIECASGGCVEHPAHSWEDVSIVLSQADKSFGHTGGWEHGATGGEMSSPDGGKTWNFSTLNIPAQKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULC9</accession>
    <name>A0AAD8ULC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Appr-1-p processing domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_542722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363723.1">
        <property type="nucleotide sequence ID" value="XM_060503412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULC9"/>
    <dbReference type="GeneID" id="85387311"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF121">
        <property type="entry name" value="ADP-RIBOSE 1''-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Macro" evidence="6">
        <location>
            <begin position="97"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="458" mass="50248" checksum="556A8E2188AFA4B4" modified="2024-05-29" version="1" fragment="single">MDNIQQILVHLLDEADSGADSDHGDCDHGHHHHHLRHIKDQLDDLEPPTHLQLLHQLLCVRTPDPPLPEDILIGIDSVLQQQASHRVLTLAGSIQPTLTLKRPNHKSVRVTLWQGDITTLTGITAITNAANSQGLGCFQPPHRCIDNIIHSAAGPRLRDECYRVMIKRGRELGPGEAIVTDAYCLPANHVVHTVGPQLQRGSKPTTNETLQLAQCYRSVLDAVEPLPATPDGRKIVALCGISTGLFAYPARDAAAVAVSAVADWLEHHEDTSITDIIFNTFTNADHAVYQEILASPPHISTWMGQAAPTFTPPASANHPPLIQCDSLDRARQWLDAADAVIVSAGAGLSASDGLDYTSSALFAKNFPGFLKYGLRTLYSVFGFNSWPTEQVRWGYYFTHLAMVKSWPASRMYRTLISWLERFGENAHVRTSNADGLFVANGLSPERLSTPQGSYSVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULG6</accession>
    <name>A0AAD8ULG6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Cation-transporting ATPase 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_626622</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[protein]-with a C-terminal TM segment(out) + ATP + H2O = [protein]-with a C-terminal TM segment(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66168"/>
            <dbReference type="Rhea" id="RHEA-COMP:16963"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:90782"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363319.1">
        <property type="nucleotide sequence ID" value="XM_060508576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85392475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07543">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000049">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000054">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000071">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057255">
        <property type="entry name" value="2TM_P5A-ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047820">
        <property type="entry name" value="P5A-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23143">
        <property type="entry name" value="2TM_P5A-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1111"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1194"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1233"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="domain" description="P5A-ATPase transmembrane helical hairpin" evidence="17">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="256"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1280"/>
            <end position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1723264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1321" mass="147282" checksum="3E23C5A65AE8C91E" modified="2024-05-29" version="1">MAPLVDNPQIKVAELWKPLPTYFHAYVWPFAIIWPIFLRYYLTAELYEKHIASEEWTFVWIGSIVTLQSLAWLSTHWSVNLQATFTATRAKSIDEAELVKIIPVANAGSADICKIIRDKVGGKINTTFLFQKRRFIYFPEDKSFRTLAYDIDAEPKPKIGRYQQSKGITTEAELKRIEEHYGANAFDIPVPTFTELFKEHAVAPFFVFQVFCVGLWMLDEYWYYSLFTLFMLVAFESTVVWQRQRTLNEFRGMSIKPYDVYVYRLGKWTEVLSDKLLPGDLVSVGRTKEDSGVACDMLLVEGTAIVNEAMLSGESTPLLKDSVQLRPSDASIEPEGLDKNAFLWGGTKVLQITHGNPDEEKPKLASGVPPPPDNGAMAIVQKTGFETSQGSLVRTMIYSTERVSANNVEALLFILFLLIFAIAASWYVWDEGVKKDRKRSKLLLDCVLIVTSVVPPELPMELSLAVNTSLAALAKLAIFCTEPFRIPYAGRIDIACFDKTGTLTGEDLVVEGIAGLGLGQEGTSTPREADGAHSTMTPVNEIRLDTTLVLATAHALVKLDEGEVVGDPMEKATLTSLGWTLGRNDTLASKPTTAATTGVSGTVQIKRRFQFSSALKRQSTVATVNGAGKAGNRIRGTFVAVKGAPETIMKRLTIIPADYEETYKYFTRRGSRVLALAYKQLTVDNELGGSKINDLKRDNVESGLTFAGFLVLSCPLKDDAKQAVQMLNESSHRVVMITGDNPLTAVYVARDVEIVDREVLILDAPEDNEGGDKLVWRSVDEKTIIPADPSKPLDPKILENNDLCVTGYALAKFKDQVGWRQILRHAWVYARVSPKQKEDILVGLRDMGYYTLMAGDGTNDVGALKQAHIGIALLNGTMDDLTRIAEHSRNTKMKEIYQKQVDLMKRFNQPAPPVPVMIAHLYPPGTSNPHFTKAVEREAQKKNITPEEWLKANGVSAIETVTSPGAKQLLNNNDPNAARQAKAAANAASFADKMTSSLMETEMGDDEPPTLKLGDASVAAPFTSKLRNVIAVPNIIRQGRCTLVATIQTYKILALNCLISAYSLSVLYLEGIKFGDGQYTISGILMSVCFLSISRARVVEGLSKERPQPNIFNFYIIGSILGQFAVHVVTLIYIARFCDRLEPRSGDVDLEAEFAPSLLNSAVYLLQLIQQISTFAINYQGRPFREGLRENKGMFYGIVGVSALAFSCSMEFIPEINEQMKLVPFSDEFKMTMTGIMVVDYAACWVIEVVLKNLFSDFRPRDIAARRPEQLERERVRKAAEQKIKDEEEEKKAQEKVAEFERKVEERRQQLEAWRTGRQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULG9</accession>
    <name>A0AAD8ULG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_791892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365578.1">
        <property type="nucleotide sequence ID" value="XM_060515742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULG9"/>
    <dbReference type="GeneID" id="85399640"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="277" mass="29061" checksum="E25FBC2F2634E29D" modified="2024-05-29" version="1">MEVSSQTTLFVCRTATIVQCFTKQPFAPLRGSCMATPAVGLPAVTGQPITVQLQAPNCNKCGCDTCVHTVFYTTEYDAFCSTGLAKQMYAVTETYRGMPSKPTVTSTGVPFGFTAEVQTCTTCGPTPVVATITRPVSEVAQDVRASGVITIPAGIDPQYSLFSMTDFPSAALPSESTRVTAAQNPQGLVLQSGSAPGETLPLSKDTSLTASLHGAVTAHESNPEQAPTMGLLDLSVMPSLPATTSLPITNTVSGSLKQYGPSAIYKFILWSWVSDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULR3</accession>
    <name>A0AAD8ULR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_386264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363726.1">
        <property type="nucleotide sequence ID" value="XM_060502746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULR3"/>
    <dbReference type="GeneID" id="85386645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="207"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="765" mass="87002" checksum="1801957689448898" modified="2024-05-29" version="1">MGSHLQNTETHYMNASTVTSMARDVSKSLQYYGGKSQGAQWLPVNQLFRIVTRDSVFRALRECRPKLELSETKLWKYAEDICPRSRPDGSCLMGARSMFAILTILERVNEIIQFIDLNLSDYNLPFVPDANQPSLDGQLFPKNPPPGFANQIFGRHWTLRDWGAFERYQKTMRSPFFDIGPNDKERNIHHYELEPDTVLPFIKEFPATSSDITSYSKVQRVQIHMHHHTMHKGVPDENPFFAVKELLPEPDDKMDTSREKNFRAEVRALAKTVGLSSHDHVIKLLATWRKGDSWSMLFPWAISNLKDYWKRGEPERSPEFVKWISTQCRGLAEGLQKIHKSPSDHADHAQEYGIHGDIKPENILLFHSDSNPFGIMVISDFGYTRFHRRNTRSNTPAAGYSPTHRAPELDLEKFISRSYDMWTFGCVFLEFITWYLMGPEGIGEFVGCRTADDTGAPIGIKEDKFFIPSIEENGEKEATVKPSVNDWIDGLRRQPYCGGYFRDFLDLIVKDLLQPKPGKRESCANIAGQLRELEHRCKIEPPDMEYLMGQVSESTTARSLSRTKQHSQQSDAEMNARAYSPLLGSLCDETWGPKSDRGSLNCASYGEMENIADIFSRDGPAYETAQKVHRLTTRSLRMELKAQSTERTPLITKIDSCLPDDTRPTLPGAQRLGEASEGGACLRTRDRPFEAQEMSPRIRARDGQSHLSTDGRHGDRASDSRSIEYKRPGSFLSVYSDGHWCGLEDVFQCCFASSENSTSSQDLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULS0</accession>
    <name>A0AAD8ULS0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cyanide hydratase</fullName>
            <shortName evidence="7">CHT</shortName>
            <ecNumber evidence="2 7">4.2.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cyanide-degrading nitrilase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Formamide hydrolyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_751966</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>formamide = hydrogen cyanide + H2O</text>
            <dbReference type="Rhea" id="RHEA:21720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16397"/>
            <dbReference type="ChEBI" id="CHEBI:18407"/>
            <dbReference type="EC" id="4.2.1.66"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Oligomer of dimers, forming left-handed helical fibers.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By cyanide.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.66" evidence="2 7"/>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365222.1">
        <property type="nucleotide sequence ID" value="XM_060514128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULS0"/>
    <dbReference type="GeneID" id="85398026"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030196">
        <property type="term" value="F:cyanide hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
        <property type="term" value="F:nitrilase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019500">
        <property type="term" value="P:cyanide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07564">
        <property type="entry name" value="nitrilases_CHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.110.10:FF:000011">
        <property type="entry name" value="Cyanide hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03224">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037544">
        <property type="entry name" value="CN_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044149">
        <property type="entry name" value="Nitrilases_CHs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044:SF4">
        <property type="entry name" value="CYANIDE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46044">
        <property type="entry name" value="NITRILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00921">
        <property type="entry name" value="NITRIL_CHT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="340"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="42106" checksum="D51BF881D37D2B78" modified="2024-05-29" version="1">MPITKYKAAAVTSEPGWFDLEGGVQKTINFINEAGQAGCKLVAFPEVWIPGYPYWMWKVTYLQSLPMLKKYRENSLRVDSEEMRRIRRAARDNQIFVSMGFAELDHATLYLAQVFIDPTGAIINHRRKIKPTHVEKLVYGDGSGDTFMSVSETEIGRVGQLNCWENMNPFLKSLNVSQGEQVHVAGWPIYPGVQRQVSPDPATNYADTASELVTPAYAIETGTWVLAPFQRLSVEGLKKNTPEGVEPETDPSDYNGHARIYKPDGSLAVPKPDKDFDGLMFVDIDLNETHLTKVLADFAGHYMRPDLIRLLVDTRRKELVTEADPQGGIASYSTYHRLGLDRPLDSKPELHERDEQETAKRISKEPAAKPVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULT4</accession>
    <name>A0AAD8ULT4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_623730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364199.1">
        <property type="nucleotide sequence ID" value="XM_060508392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULT4"/>
    <dbReference type="GeneID" id="85392291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="63887" checksum="E8EBBF70765C099D" modified="2024-05-29" version="1">MRNEDLKKPAKYVLPYRKGDENQDTYELMPLPGPAPDPNLHRFAEIPIKIKSKRVRLVRRLQKKPRLYKLVPIQDSTFHQFAKLPDKIKSRVWREFYLEPRYYIAELHPKDHKIEGKDYNWDLESCDEELSGEEPCVEHMAEEDASKEMTPEDNSSKNSTPQSDALHTNALKQQPYDEYLSDEYSSEEESSEDEVAENGDAEDGTAENGTVENGAIRDRAIDDPFDELEFGQVEDELDNVEGRDSTDSLVRPSSNASNPFDKENEETDKQTHRTVFWTLSRQDAEYSDGYYDSVDTKIDSLSRSVAQSVRSPFWFPTFVKDELEQGEEGPWMAIPPPKDPASKMGKSVTINWDIDFVHLKVRFRKCVTESIGWMQNIQNLVVDTKPFIARRPQHVTNTCLWMWTNKATLANLKTIRQIAAPEYQVPFWHSEWCHYQIRHLLRFAPGTPPQWRDIQSELVSDEFWLPPDNLPRQPQWKKFVRDFFGKLRHAVGSRTFKNYMRVPHRSDKDEAKGARVLFDVVKRHPSHFHGVLFHSPDKCGHNFTAAEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMN1</accession>
    <name>A0AAD8UMN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_574110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366676.1">
        <property type="nucleotide sequence ID" value="XM_060504684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMN1"/>
    <dbReference type="GeneID" id="85388583"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF8">
        <property type="entry name" value="S-TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00590)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="94"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="25914" checksum="C7EC4935F3901FBE" modified="2024-05-29" version="1">MSSAAPKIKLYTNHGCPWAHRAHIALAELGLPFEEEIIDLSVPRTKEYLAINPRGLVPSLSYDGEIITESAIVSQFLADAHPSHLVPAAGSKDAALRRARINFFVDTYFSKANSSLYKLQLAKSEAEANEVAAGFIDVIAKEVEPLLKDAKPYFGGSDKVTLAEVLTGSFTLRLFSFANYELIPKNILTSLEEKAPSFYKWAQTVNSTPSVNGIYDEKNVVERTKHRIAAMKAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNJ1</accession>
    <name>A0AAD8UNJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365129.1">
        <property type="nucleotide sequence ID" value="XM_060508229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNJ1"/>
    <dbReference type="GeneID" id="85392128"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="874" mass="98010" checksum="C218B89531AE2DDC" modified="2024-05-29" version="1">MREYHAKAKAEYIKRHQREPSPPIASPPDNEEAPANSKGKERMREEQTSEERVREWQSKSASPGDDDSRRAQGDRSDESSSGSVTESSLDFSFDGDSIDVAVPPTFPSFAKRSRAAPSYKVPRPFAPPNPPAGRQHSRLNRQRSWRHQSFPEPPYGGRGKPAMGEAPINTPMSTFYHLPQQSEAETPYNPYDISEAMKDQSPRQSKANQPKVNVDPQNPQDITIHTELVATIDLEEELEDYSRLVRLGRFKAAQKFFTYKLSGFIENSYVLDHYCEGLAAMPDFHKLSQIGETFVPGPQCGVVQAHTYMLLSKADFVGGVSMLSRAANRQPPDWENCMKTVWEHWPKLDSTEIQILAGGLSPKENVAKFHHNEIAEVYLHLRAEGRIWEFGDLLQVLLRGSREPACQVLEVLLHCDLGDGRDRLIKLIQAIEEDWSVAETNEETSFALLEIFTTIVLDSMCQSENIGLVNTIFEFSRKKALDVLELNPTNSKSRPYLRWIISKVLLEQYRDPRITGFFSLKRCLHNFPGHRIAPNLSDLPKLCMISYAPDEDEAPRWSPDPTTTIGHDEVLRTVLGVAEELGDVWMQATCLQLLIYQSPEPRTLLYSLDDLWRSAGTHQRHLETRLYRYIPEALRTTEDRAGLQRQILLSAKASSQGLKPYAEYMILRALATRQEEKDSYLERAMDALNSSFQGYVPQSHTQFPTENPSARNTAGHDWINGNISAPLGGPWQNIPSGTSGEANYVGTQYPHMGYAPAQGNTYAAGLAPFRETRTTGNPGYIGVPTNTPYVTSNDRFGWTGGAQSGPFGQYQTNFGTPYAQNQFPHRQPPQPPPPPPPPPPPSPPPTKTPATGTNFDWGRQHPSGPGPKTKLKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNQ4</accession>
    <name>A0AAD8UNQ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_700424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364489.1">
        <property type="nucleotide sequence ID" value="XM_060511428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNQ4"/>
    <dbReference type="GeneID" id="85395326"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="58491" checksum="1956FF7DAA0720F8" modified="2024-05-29" version="1">MTLPRLGKASSYPSSAHSADAITEPVEPTKLPKPLDVRIPNRVEQAGPFPWPERFFNRRKLPSDWENTPWLYATLRDMEQDLKCPEEEDILRSLRTEENWAPDQFRLDVFLDIIQGRTLQQLEEDGDGVPETKVALLIDSNNVGSKPEFRPLLGGLSARQLLREATKERYELDYEQSTVSSGFVEAERRLIYVVDLDSWSILALLGSSPESLYREVTECILNHLSAKSEIGVSFAVRQHKKLLDDFLLASRNLRAQQEAERKLNECEMMVKEAGDVLRDLKRTLGETLSSAAVFTETDVNYFLHQDGRVGDAIDCMMPLSQIRKTLNKMGRTHRDIGELQGTCESMLESGIRGRKKSMLTPNMNATNTLEKRMLLWITMMSQPLLNVAAIFSCDGIITFPRTWYNFLYALFFMVAAMGSIVVLLLKLLESGVSLFESRAGGQSSAEETSDCSRERGGTGPVDASNRLPPRRSTWCTSGMGHIQRRHAGDIGLLDLPGRSVLGQPATIGPSLNKPSTAVLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNW7</accession>
    <name>A0AAD8UNW7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_620245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365309.1">
        <property type="nucleotide sequence ID" value="XM_060508181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNW7"/>
    <dbReference type="GeneID" id="85392080"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="56307" checksum="34AF694E9A67EA2E" modified="2024-05-29" version="1">MGLINAPTALVVAAISLLIYAIFGQPKLRRNGVPLRRPPNTLPLAGNGIIFLRNRQKLFDWFTKCEQLYGYETLQISVPSLPPGVIISDPKNLEYVFKNEGIFAKGEFFKGRSRDLFGNGIINVDGELWKVQRKAGLNFLHTSNLRVLTDVALPQYLSQSVAYLGSQSGNDVVDLQAVFHEITTQLMGKMAYNMEMHAEDTFGLAFDYASGATAERFQNPTWFLTEMLTGARLKKSISVVKSFGQSIVSSAMTDRKASPKTASVVSQDLGSDRLNDISGSLVQSLLDSIGDEQLVADAALNYLSAGKDTTAQALTWTFYLLMQHPEVVAKVREEVDGIKENSEDTLEKAIAERGNPNTMPYVFSVFYEALRIFPPIPFEIKQAVQATTLPDGTFLPQNSVIVWCTWAMNRSRTTWGSNADQFRPERWLVDGKVINKSTSEFPVFNGGPRTCLGKKMAEIIAVQVIATVAGLFDCVRVDDSTRVSKSSLTLPMKDGLPCFIRRRPDVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP31</accession>
    <name>A0AAD8UP31_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Superoxide dismutase</fullName>
            <ecNumber evidence="13">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_577129</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 18">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365193.1">
        <property type="nucleotide sequence ID" value="XM_060504989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP31"/>
    <dbReference type="GeneID" id="85388888"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000004">
        <property type="entry name" value="Superoxide dismutase [Fe]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF29">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="14">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="15">
        <location>
            <begin position="96"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1725138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="23142" checksum="110992DFBE4FE204" modified="2024-05-29" version="1">MASAQYTLPKLPYAYDALEPHISAQIMELHHSKHHQTYVTNLNKAIETYNANPLQSRFAVLAALNFHGGGHINHSLFWENLSPASSPDASPDAAPKLIAEITRIWDGLDQFKVAFNTALLGITGSGWGWLVKDDVTGLSIVTTKDQDPVTKGVPIFGVDMWEHAYYLQYLNGKAAYVENIWNVINWKTSELRFSGSRDDAFKALKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPA1</accession>
    <name>A0AAD8UPA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_148888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368142.1">
        <property type="nucleotide sequence ID" value="XM_060501314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPA1"/>
    <dbReference type="GeneID" id="85385213"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF1">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="179"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="761" mass="86120" checksum="E4CB993787F45DEC" modified="2024-05-29" version="1">MGREKKPHPGPGTTAKDRHRKAGKINKAIDRSQPLPPGLVAAKPVTVVSNSKHQSYFEFIENKDKKKPLLFQITTNKTPPPGMRHIPLGNPELTERCKDISRETGASVYIVTMAKNNASDLSQQIHRVGHHIREYIVDRALEELGLDSVNEPELIGQGDAQVEKIPEKQNDIDKQADAALRELFPRIPNTDRQQIIDHAFQKGTKFKGDLVVGLQQELSLSRRVQLAVLAHIRHNHTRYDQLLRETTWHNARRVTEQLCLDFLVKWRGDDENGRDQLDEILREVVVLSDDSDEEDSDEEPDSDSSEVLITRSNNIGRLSTPAVAQNVANRDKRLSTAIPSHPGSPMLIATPGMSRRAYKKARRRAKHRERNFSRYEAAANAAWDNARQRQRGPDDRMNQAGSSVSHGAHQQGPPVEFIENRAPMEHINHAGSQMRLPPAPPNHAGARARESHQLQDFLHPSIEPRSPDGVRSPSRYSRGVVEFTDRRGDELYPRLNSPPRGPLVREERYVHQAPPIHQSHPIHARPLRDGQDVVPPPESLYRNVPQDSHRPLVYQQPVRDHGPSRPQIYADRTIHRENNLRRRQGSVPGERANPIMIEDHNVHQGTVVLGTGESVRDRFGPNAEILAVHRPGRDRGHRGPDSQRFNSMDEGFIRLRENNIDQRNGLVEEGFLRLRERPVVDPRHSACGIDGRSRLDDHRATHQPQPYRPAEPSGQAIYVRRVERPPRADVSYPAHSYERVEAVRNDSLAQRGVPSPTYGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPB0</accession>
    <name>A0AAD8UPB0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_750790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366467.1">
        <property type="nucleotide sequence ID" value="XM_060513964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPB0"/>
    <dbReference type="GeneID" id="85397862"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="9"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="60346" checksum="6E381CED6D9A0310" modified="2024-05-29" version="1">MGSTFQDARPSVKLTQGTVIGTVVSDSLPRPVEAFKGIPYALPPTGDRRFRAPVKVEPSTKEIDASKWGPVAPGKQLFPGGPAFEYSEDCLSANVFRPVSSSRDGTLLPVAVYIHGGAFNRGTAMMHNTASFLANSGQAFIAVSFNYRVGALGFLPSTKSFEEGSVNLGLKDQLILLEWVRDNITAFGGDPNNVTLFGISAGAHSIGHILINDEGQYNPPLFHKVILESGAPTSRAVRPYSAPIHEAQFADFLAETGCPPDLSAAETFAYLRAAPTEVVQKAQIAVFDKYNPSLRWAFQPVVDGDIIPRPPMESWRLNKWRKVPIMTGFNRNEGSIYISKTVSKSDQFTSFFADLLPLLSKEDVETIDKLYPDPLTIPTSPYKESLDGTGAQYRRLEIAYGQYAYVAPVRQTADLASRADPALPIYLYQWGLESSLLDRARHGENMYYEACEPAKTKISPTQKELCLTLNAYLASFIVAGDPNAVRGESAPERPTWERYVAEDPKALVFAEENKELIGGEAGVPARLCADTWARKESEFWWTKVDVSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPK2</accession>
    <name>A0AAD8UPK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_579464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364175.1">
        <property type="nucleotide sequence ID" value="XM_060505242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPK2"/>
    <dbReference type="GeneID" id="85389141"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF15">
        <property type="entry name" value="TRANSPORTER SEO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="453"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="488" mass="54996" checksum="9EA7EAC7B74D3CC6" modified="2024-05-29" version="1">MVVQARRKWWHIQWYADTDTPEERKLINRLDLLIVPYAVLSYWVKYIDQSNLNNAYVAGLKEDLGFKGNELVQLQTFYIIGAVTGQLPMMFVLTYIPIHWLIPFLDIAWGVFTLLQFRVTGFAELAAYRFLVGWFEAAFFPVMHYLFGSWYRGDEIARRGGIFYVGLSLGTLTAGLIQAGASARLDGVHGLAGWRWMYIICSLITIPIGILGYFVIPGTPEQPNRLVLKRENIELSVERLKRAGHSSHGKFKFSNLKKVFFSWQFWGIIVVDVLFWNAGIHTSSGSFLLWIKSLGRYSAAKVNELGTIAPALGIFYTLFVCFASDLLMGPAWAITMSSAWNALGLLILTIWNVPEPAKWFAFSTIYSSVALSSVFHGWVNTQLRSSPAERSFTLVLINAISQSSTAWTPLLVFPTVEAPRYPKGFAFTLACAILLIVATHILRMYVKRRDPQLENSAGFPESDHEDISTIEHGKQPPVAVSGRDDRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPR1</accession>
    <name>A0AAD8UPR1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_611800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367771.1">
        <property type="nucleotide sequence ID" value="XM_060507681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPR1"/>
    <dbReference type="GeneID" id="85391580"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="194"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="236"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="318" mass="33972" checksum="FF97597162EF574E" modified="2024-05-29" version="1">MSKQYLTTHTVDNAHITDIFSLATTSRAVLSASGSSTLHIHDTADPTISITQSISGAHKLGCHHICTSRNGLVAASAGFAGEVKIWVINKDTSEWKLHSEITNKAAKAGEVWAIALSEDGKFLAGTTYDGRVNVWDVGEEGTPKIREYETGSPGQGSFGMSVDLSRDGRYTASGHQNGAVYVFNNDNGKLLFSLPGLVKSVRSVAFSPGNTRLAAAGDSSVIALYDIKNGEQVSNMTGHSSWITSVDWNDTGEYLLSGAMDGKVKVWSVERSACVATHSETDKALWAVKWLPKTGKNESFCTAGANRSISFYREATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPZ7</accession>
    <name>A0AAD8UPZ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Prp31 C terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_575685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365849.1">
        <property type="nucleotide sequence ID" value="XM_060504837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPZ7"/>
    <dbReference type="GeneID" id="85388736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000002">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein Prp31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000003">
        <property type="entry name" value="U4/U6 small nuclear ribonucleoprotein PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027105">
        <property type="entry name" value="Prp31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019175">
        <property type="entry name" value="Prp31_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09785">
        <property type="entry name" value="Prp31_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="270"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="384"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="570"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="570"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="581"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="608" mass="64998" checksum="E40F9C834EED189D" modified="2024-05-29" version="1">MATLADELLNDFEDSGSEAEETQQDNDPLGLDHAPEASGRKASGGMDLDDDQSEPEDQDEEMGGTPKGAVDPVEDAEDTKAKVEKMQLGGVNDVRSVASLMSSLEPVLEKIAHYQSQPTPTELLGNIEDHPEYHLLTQSNSLSTLIDSEIVLVHKYIRDHYSIRFPELETLITNPLEYAKVVAILGNGPLDSENIKKLQHSTDNVLQASLKSVLDGPSLMIVTVEATTTKGRDMSQEELERVYRACEMVISLDKAKKTLTGYVQSRMNLFAPNLTAMIGSLTAAQLLNAAGGLTGLSKTPACNIAAWGSKKGAGAAGLATNIGVRQQGFLYHSPIIQGIPNDLKRQAMRIVSAKLLLAARVDRIHSSADGSTGEDLKEQCLTRLEKLTEPPPNKGPRALPVPDDKPSRKRGGRRARKAKEATAMTELRKAQNRMAFGKEEREVGYGTGETTVGMGMIGQGNDGRIRNLQVDQRTRAKLGQKNKGWGGATPMGGAASSLKGFGQSANSNIDLRGKGLRTSGVGTSLGAGAGTASSLAFTPVQGLELVDPKVQAELSRKRKAEEDRWFKGGTFTQVAGSSNDGFKKPDLPPSKRVDTGAGKMGPPPPRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ11</accession>
    <name>A0AAD8UQ11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_652212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364430.1">
        <property type="nucleotide sequence ID" value="XM_060510508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ11"/>
    <dbReference type="GeneID" id="85394407"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="54"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="17689" checksum="F787400088F4F7F5" modified="2024-05-29" version="1">MCYFYCIQTPEHQGSGGDATIAVPSGSTTASATATAGPTPPAPTLDGQPSNCNKWHVVAAGDNCGVIESEYSLTHSQFLEWNPASSEDCLTGFWGAYAYCVGVSGGGGAVTTAPPATTTSAAPAEPTNGPVAAPEPNQAGNAIAFCNKDGQAQSGDWCSAFADRYGLAYSDFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQN5</accession>
    <name>A0AAD8UQN5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipase B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_578179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364745.1">
        <property type="nucleotide sequence ID" value="XM_060505094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQN5"/>
    <dbReference type="GeneID" id="85388993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053228">
        <property type="entry name" value="Stereospecific_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574:SF1">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154663" description="Lipase B" evidence="2">
        <location>
            <begin position="21"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="42090" checksum="02A66CD490160C06" modified="2024-05-29" version="1">MKTTSAAALVLILGWTQVLARPVNDPNINVRDANANVSPVAIESRPLEPDRQALNPFLGEDKNSIKNDNPDPKTKIYPKRSEKDAPYSRSERDLKASIYIPKTFSASSNKQPVILVPGTAAMAGTTYRANLGPLLAKSDFADPLWVNIPDASLDDAQENSEYVAYAINYVQDMTGKKPAVVAWSQGNLNVQWALKYWPSTRDSVTDLVSMSPDFHGTKEAFAACKTPAAIIGCTPSVYQQMYDSKFVQTLRANGGDSAYVPTTSIFSATDEVVQPQSGPIASAMLKDGNGVAVSNIEVQKACPATPAGGEVTHEGMLYNSLAFALLKDALTNEGPGKLDRIDKKICADPAAGKLDALEIQATEAVLVDAGANVLAYPNKVRREPAIKDYAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR66</accession>
    <name>A0AAD8UR66_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_616857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366288.1">
        <property type="nucleotide sequence ID" value="XM_060507998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR66"/>
    <dbReference type="GeneID" id="85391897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="181" mass="19738" checksum="B3EC2B528CDC9733" modified="2024-05-29" version="1">MDHAHMDHSKMDHSAMDHGDMGGHGMGGGMGDRCSMNMLFTWDTKNLCIVFRQWHVRSTSGLVISLLLVVALAAGYEALRAASRRYENSVNKRVDSLPSVAGTVTETTPFLWTGREQAEASRSAHLVKAALYAAQNFYAFMLMLVFMTYNGWVMVAVAIGAFVGYAAFGSSTSSTKDNACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URX9</accession>
    <name>A0AAD8URX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-acetolactate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_615652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-acetolactate + H(+) = (R)-acetoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:21580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15686"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="4.1.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-butane-2,3-diol from pyruvate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-acetolactate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.5" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366678.1">
        <property type="nucleotide sequence ID" value="XM_060507908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URX9"/>
    <dbReference type="GeneID" id="85391807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047605">
        <property type="term" value="F:acetolactate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045151">
        <property type="term" value="P:acetoin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17299">
        <property type="entry name" value="acetolactate_decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.80">
        <property type="entry name" value="Hypothetical protein, similar to alpha- acetolactate decarboxylase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005128">
        <property type="entry name" value="Acetolactate_a_deCO2ase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01252">
        <property type="entry name" value="acetolac_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35524">
        <property type="entry name" value="ALPHA-ACETOLACTATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35524:SF1">
        <property type="entry name" value="ALPHA-ACETOLACTATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03306">
        <property type="entry name" value="AAL_decarboxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001332">
        <property type="entry name" value="Acetolac_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0005">Acetoin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26021" checksum="0BB62582BC91A9A1" modified="2024-05-29" version="1">MAVNEIFQYSIISALMDGVASKGLPVSDLISHGNQGLGTFRYMVGEMIILDGKLYQMKSDNTVTPIETSPASDAVAPFAMVTRFQPTATIKAAFSNKKELFEHLSQDFPDSKNFFLAIRIEGVFKGITVRTAGGQSKPGESLTEVGKHQASHTFEEPVRGTVVGFRSPEYTMGISVAGDHLHFITEDRTQGGHILSFGTDGEVEIGAAQISQWHVELPTNDPEFNKAALEGDKEGIAAVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US99</accession>
    <name>A0AAD8US99_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF2433 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_113472</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368638.1">
        <property type="nucleotide sequence ID" value="XM_060501107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US99"/>
    <dbReference type="GeneID" id="85385006"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018829">
        <property type="entry name" value="DUF2433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056812">
        <property type="entry name" value="RRM_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF11">
        <property type="entry name" value="DUF2433 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10360">
        <property type="entry name" value="DUF2433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25061">
        <property type="entry name" value="RRM_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2433" evidence="2">
        <location>
            <begin position="278"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding" evidence="3">
        <location>
            <begin position="509"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="71085" checksum="1DE4EB98A7CE492A" modified="2024-05-29" version="1">MAAPRPYNNNPGYMPNGASSIPPGAAPLLPNQGRVIQTGPIRVLCIADVRGNLTSLNDLARQARADHIIHTGDFGFYDDTSLERIAEKTLKHVAQYSPLISEPVKKAIQQGGPGPVKSRFPANELPLSELSLLLSGEIKLDIPVYTVWGACEDVRVLEKFRSGEYKVHNLHIIDEARSMLLELGGVKLRLLGLGGAVVMHKLFDNGEGRTTIAGGQGTMWTTLLQMGELVDTAHRVYDPTETRVFVTHASPAREGILNQLSVTLKADFSISAGLHFRYGSSYNEFSVNPTLDHYRGKLAASKASFNDVWETVKNEVEPAISQNEGQQNLLKNALQIVEKMPTTAAGGNPFGGPVAGQAQLGQVDESAFKNMWNFNLADAAFGWLVLEIQDGRIGTEMRAQGFNFSHRGAKAAAPVPAGPAGAGNLPAPAPPSTQTTAPPPTSRQPSSQAPPKPAVATPLPSAKPGTPQPAAAAPPAVPPKDERPAPAPANGSANGPEPVSSPAPKTPAQDIVGLFIMNVNSEEQTRDLFDGEHKNNILKVEKWGNSNKVVMFKTIEERDAALNSLPEDLKTRAQEDRSRPLVKVFQHRESKFQPRGGAGNWGSSRGGGNSANTGSGYRSAGGASDSESTRRGGRGGGRGGRGGERGGRGGRGRGGLKGEGGASPAPGPATPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USL1</accession>
    <name>A0AAD8USL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_650527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366409.1">
        <property type="nucleotide sequence ID" value="XM_060510379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USL1"/>
    <dbReference type="GeneID" id="85394278"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202442" evidence="1">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="147" mass="16668" checksum="E902191CE703E36B" modified="2024-05-29" version="1">MDKIIPLMAWLVLVTSAWLEGHRGMAVDESKEDLRQEELKLHWRSVVRFFPISPYLVDTLPTNVIWGRDLRQAGRQAGRQAGIWQVHKKPRQPPRVQESPALIVSNLAAWPQQASSSLIALLAWLQTLLWVDPVPSSTDTFGLRSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT21</accession>
    <name>A0AAD8UT21_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-1,2-mannosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_574277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366664.1">
        <property type="nucleotide sequence ID" value="XM_060504698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT21"/>
    <dbReference type="GeneID" id="85388597"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021848">
        <property type="entry name" value="HODM_asu-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11927">
        <property type="entry name" value="HODM_asu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="54816" checksum="FFCF1A512CA837C2" modified="2024-05-29" version="1">MSFAIELGDHYAFTTVLGIAAFTGALLYLISTLIDSRKVFSRFNRAPSFSQPAEKPSVTTAEKQSYVNTFPPSQRTTIAELGPHFADVKEVDLAVTPKPLLRVDANYRSADPSLFNFSGFSIDDIQKLGDFPDYAAISGVPLPSPLANFDIDKAVPRPYRPFRWAYHQTMSLTKMDTDFWIELENTYRERVAERKDLYAKNGSDVLDSMPGSELACKELMEMVIQFICARYPNQFKLEGNVLYNNILGTTTDLSATEPLIVLLDNVPEDFGIMLRDHETGKYVLRAGIICSSVGWKLSEKAGLGLPGIHKVVPDYKEKMEFSMDRFFTKMPTNKPIQRGSWGLEKGQPLYLPSEHPEFSHREHQNPSLQPEDVHLRVDWQTLRRLPLSGGVVFNFKALFTPLTEFKDEPYIPSLVLKVLNEGKESLLKYKGTWHVEHVVKPTLKEYEKYQVENGLIEKDWEPQTLAEAPFFKGWEKKWTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT97</accession>
    <name>A0AAD8UT97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_252430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366784.1">
        <property type="nucleotide sequence ID" value="XM_060501937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT97"/>
    <dbReference type="GeneID" id="85385836"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="382"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="674" mass="72778" checksum="72B28177BB529679" modified="2024-05-29" version="1">MDEAMDYAYHHPEQSQSQAQNPYAQQRPRCPYFLNREGQQQLPGMPQHRSTMHYDPVHSSANYTSWQPQGPPLPGPYHWQHQPQMMNHRGHPAPQHRPSNSASEAPYYNHVPVPNFGNVAGGYSGAPPSEMVGPPTMQPSFPHTQLPPVRFNFPTALPAGHPAQGQPFYTSSERNFGGQNAAPRHSAFNTASHSVNTSTPSVAQTSSEHLAGAPNPPQIEMSESTGGTVQAPSSGASIQFGSAPPSTAPHRSTSTFLNPPHDVHQPTSGASSSGASSSSSNLGSHHHPERRRVPAIRRASRRQSPLSDSDVDSDRGALEQVIALAGNPTQMARHIMTLEEDHVRAAQFMRGSVTTKYVASSSAIQSLQSVPIAELSESERTCVICYNEFGVETPEGVKEAPLRLPKCKHVFGDHCIKKWFEESDSCPYCRDKVPHEPRITSTHPNFDRYYRNRGHVNLGGLAGYAGYMRDRDASLAQEDSNRSQGSGSSHGERRSPPTDSGESRRRIRPRTGVQGPGSPTFSSSRPRPVSSTYDSNRRAHAAIPALLPPRGAFASNGSSRTNHGGISQVSFSSSNMHQHHHQATGFAGLGETGSASTQGVPILARHPNGAAPTALGVPDGLHGNGYLNPNNRTSLPAALPSAWIGDLTAPEESHRRMMGGENGVSLQANPWVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTE9</accession>
    <name>A0AAD8UTE9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368205.1">
        <property type="nucleotide sequence ID" value="XM_060510235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTE9"/>
    <dbReference type="GeneID" id="85394134"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041924290" description="Inhibitor I9 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11167" checksum="1575EA66795E055B" modified="2024-05-29" version="1">MRPSTFLVAALAVVPGALAVDQMKSVIVWAKTDSVGDDIIQRAKQSIIDAGGEALLFNRFEVFESQLTTIRGFAAVTPAKVLESVQAFSESLTIEEDHTVTNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTP8</accession>
    <name>A0AAD8UTP8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_612300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367638.1">
        <property type="nucleotide sequence ID" value="XM_060507709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTP8"/>
    <dbReference type="GeneID" id="85391608"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="62" mass="6872" checksum="5AEEDF5476DC5B85" modified="2024-05-29" version="1">MKVLPGIPLSASWRLEPATVCRVQHHHGFASTPSLSSTECSLSNRSRSLKRYHPDVGLDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUM2</accession>
    <name>A0AAD8UUM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_197500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367671.1">
        <property type="nucleotide sequence ID" value="XM_060501636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUM2"/>
    <dbReference type="GeneID" id="85385535"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="103" mass="11564" checksum="B768CAFD2AE1BE98" modified="2024-05-29" version="1">MSPFRHSTRIHSCKADNLHPHRQPPSTPGFWPPSKASRSTTQRRRKAHARHRTPSKPRVNSPQAQRRSRSPACRDSELRQEMVASTAEDVTGGVALDSFAISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW05</accession>
    <name>A0AAD8UW05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_717187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368376.1">
        <property type="nucleotide sequence ID" value="XM_060511919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW05"/>
    <dbReference type="GeneID" id="85395817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12183">
        <property type="entry name" value="LDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="33"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="127"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="40347" checksum="B6D62E3AEBC75B1B" modified="2024-05-29" version="1">MKLAVFSAKAYDKKYINAAHDVRKEEFKKHNAKLVDDNTDFGIIYHDFSLSTETVSLVKDVDAVCVFVNDSLTADVVEELHKAGCRAILLRCAGFNNVDLKTAEKLGIFVANVPSYSPEAVAEFAVALLQSLNRRTHRAYNRTREGNFNLDGLLGKTVHGKTVGIIGTGRIGVSMARIMKGFGCTLYAFDPYESDAFKELGEYLPLEELLPKCDFISLHCPLMEKTKHIINEKTLKQMKPGAMLINTSRGGLVDTKSVVHALKTKHLGGLALDVYEGEGDLFYNDHSGHIIDDDLLTRLMTFPNVLICGHQGFFTEEALQEISECTFRNLEDFMLGRKCNNSLVKEEFVMSRRESLPVRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW79</accession>
    <name>A0AAD8UW79_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_749148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368496.1">
        <property type="nucleotide sequence ID" value="XM_060513727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW79"/>
    <dbReference type="GeneID" id="85397625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050031">
        <property type="term" value="F:L-pipecolate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF46">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="52209" checksum="76219CC54602F83D" modified="2024-05-29" version="1">MPSDPAAAAAAATEPAPSSILIIGSGVFGLTTAYELAQRPRYASTKITVLDRSPIPGPSEDAASVDSSRIIRADYADPAYATLAAEAQTEWRKTSHPSDLGAEGRYSQSGLCLVADPVATASTSYFSSSSASAAKTNADAKQKAKKTSLEYVRESYNNVVSLAGKDGDKIIKELPTPTAIKDYLGTPEAPGTWGYINPLAGWADAGASMSYLARKVVALNRVTFVSGVATRLNYTLDKSTVTGATLQDGSVLSADLVIVAAGAWTGALVDLSGQAIATGQAVGYIDITPSELEVLRKMPVTLNFSTGLFMIPPSGLQLKVARHAFGYLNPTAIPHPSPSTPPSTKSTVSLPATHLTDANLKFPAEGVAALRKAVRTIVPIPAIHDRPFVHTRLCWYTDTQTGDFLVCHHPTARNLFVATGGSGHGFKFLPVLGREIVNVLEGRGDEVFSEKWRWREVKSKADVTDLYEHIMTEDGSRGGIPGLLLKQEQAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWA0</accession>
    <name>A0AAD8UWA0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Atos-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_543485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367520.1">
        <property type="nucleotide sequence ID" value="XM_060503422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWA0"/>
    <dbReference type="GeneID" id="85387321"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033473">
        <property type="entry name" value="Atos-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025261">
        <property type="entry name" value="Atos-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13889">
        <property type="entry name" value="Chromosome_seg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13915">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01177">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atos-like conserved" evidence="2">
        <location>
            <begin position="403"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="770"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="859" mass="92764" checksum="2B7470395FD206BB" modified="2024-05-29" version="1" fragment="single">MPIFQDDLEHHHHLLSSIAEHRTSAPPETPQAVPPVPQHRPSPMRRLSEESIRTELCEGPVVESPTRPSTPETDTDAAAAAAAAAVTSDRAELIERLKRGESPTWIPNRRIASPRNDLVAHNITKLESLFNNLPRPSTPKSPRPPSSSSNNSLLPPASITPERAAVDGPREDDERLREGLSIQRPRSALHSGDFTEDHQPRPRPRSRQQEVQQTAQEEETHVATNKFLASRNSWLATSPPRDFSPFQFDTRLPFPATNDDYRSVPSSLSSSFSSSFVYKPPTSPLVQSESNDQLDLSAPLDSIAITGGSPSFAGPSRRHTLNSVTSSPFTFPSPSHGTVHRQSSHRGPAALPYQAHQPRRSLTSIPQMPLPGTASSPQTPAAFLRPRRPSFNSDTSPLQHASMVGSYEESILRGRMSTTPSKPLDFLAQIGVLGLGKCKSSLRCPAHVTLPFPAVFYSYGGASQGRVRSEDGPSPYVGQIDLENGLPNPEEGQRSKRKMQSRYVEKKIAEDDVLMADVPADGSSDRAAQRARRRSASPRAPPGGSYRIPEKGQIQIVIKNPNKTAVKLFLVPYDLAGMEPGTKTFIRQRSYSAGPILETSTPGLEDAAAAAAAAADRPILRYLVHLHICCPSKGRFYLYKSVRIVFANRVPDGKEKLRNETTNPEPRFTPYKPIRVMHPPMSSSHSGPAATLAAEKAFRRRSAGFPLVPSAYPYAADGGSTSDGFSQSPQAAGYSQQSPSPFSFGGGHNNQPVEAVPFALSGRGRARLGSDVSDTTNTTSTTTPSILSPQSSSQASRPTTKDGWDAQIARYEKLSKGDVGYGGNAFAPSSGRGGSPGGAAEGLLSQRLRSLGVQNQGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXX3</accession>
    <name>A0AAD8UXX3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_97642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368750.1">
        <property type="nucleotide sequence ID" value="XM_060516039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXX3"/>
    <dbReference type="GeneID" id="85399937"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="432"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="665" mass="72457" checksum="43DAE2E6C606DE39" modified="2024-05-29" version="1">MAASFVDLAGIAKLGVQLATKLAIYQLGTSGSDSDIHSLSDDVLATAAALSQLREFLASDALEVSPVYRYAGREAIGDLATRCGKVYTTIIRSVYRASLAVKVVTDVDFETLGTEDLKASRLHAISDNMDWGVIEEVIETSEVQLRWLKASLLLHIQVAGIAGLQIKPRYPGSFDEELASRSLAMRLLTCKGKAAKELVEMTERKERLALADKPDTESVYESSAASSVSGSDVDDDAESWKSGETANDSRAPSVCGDKTEENAKVTPVVEIDTPPPPPPPMAAPTSFWHQPWDGGPDAGPVEIKLLAPKRRFPAKVFKSVGKWFKGIFSRNTIPSITDLELEATVLRNGPFPESFLALEPKMLRLELKRILKQSSKIPGDAFLIQDDQLRSAVQGALFRAQRKDGRTRQLITVDVTTRPDVAVVYMSVDPAAEPVHMTDVLGRKYDIPFEQCRTVQGARVSIHQRFKDVNRLWNLVRDGVYEIVDENDTVITPEAWQTTIKPGAVLHMRISAFNDGTNAGVFVPPGAPDPLTWAEPYTPPPMPPGCWRGPPMPRGMRPPGFCRPGGPGPKGCMPPPPPPPAAFPRVITVEPRERAELGFEPDFGPILTREEDLGEGRKDLGRWVALWTNATDTDFTSDSGGIPSYDDASSIMSGSSSSSDEIVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X965</accession>
    <name>A0AAD8X965_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 93 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_765361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359124.1">
        <property type="nucleotide sequence ID" value="XM_060515251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X965"/>
    <dbReference type="GeneID" id="85399149"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF3">
        <property type="entry name" value="BNR_ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042046359" description="Glycoside hydrolase family 93 protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="399" mass="43430" checksum="E3F95424B0D4ABBE" modified="2024-05-29" version="1">MMGFTIIQASVVAFLATVSLAAQISKTAVPKPWSNFNNNGVFYPEQAATSWRTLYGRTLQLPDQSLLLSWEDYDPAATLTYFPIYKSEDGGASFTAFSRVDDQVNGWGNWYQPFLYELPQPFGGFPKGTILLAGVSTPRNLSQAYIDLYASTDQGKAWTFVSHIVYGPGPETIARGDKAVWEPFLLMHEGELVCYYSTQVDPDHNQKLSHRTTKDLRQWSDEVDDVAQADAGVRPGMATVAFSPISQKYVMTFEYCGGPIASGCPVYYKVSDSPLTFGDADLQPIIPGDGQLNPNGSPFVIWTAEPGTNGTSGVFIANGSSREEVFVNSDAVDPNGWKVVNVGQWSAYSRELRIIATPESGPSNGNPKLLLTNGGNVGCSGDCYNFVANGVVDIPTYHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAG6</accession>
    <name>A0AAD8XAG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="17">BCS1 N terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_655955</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360097.1">
        <property type="nucleotide sequence ID" value="XM_060510834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAG6"/>
    <dbReference type="GeneID" id="85394733"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="16">
        <location>
            <begin position="59"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="291"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="555"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="556"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="669"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1714954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="691" mass="77014" checksum="0D55AB8BB5653C15" modified="2024-05-29" version="1">MDTITDTGYADPINTSSSTAQPPPQLALLDFFFPGFSVFTTAFQKYLGIDLNVYIPLVILCGGATFAWRYFSEYLWEKVEKHLMSTVEVRTDDEIYNILMSWVAAQKFAKNSRRFVVNTNLSSRSWFLWRWDDEEEESDESSDGGLVEISGQKKKPLAYTPSFGSHSFWYRGHLLLFKRSQNREQASYLVVSEREEISLSCFGRNPWVLKELLQEARAEYLKKDSQKTMIYRGSTRAGTTEPTWQRCMARTSRPFSTVILNEKTKKELVDDVADYLSPVTRKWYSNRGIPWRRGYLLTGPPGTGKSSLSLALAGFFKMRIYIVSLSSISANEENLATLFAELPRRCVVLLEDIDTAGLTHTRENGTGTGGDAADAKDGGDMVPGQLTAGNGANNTSGRLSLSGLLNILDGVASQEGRVLIMTTNHVEKLDKALIRPGRVDQIVKFTLADGEIIGAIFRAIYAPLEGDEDIAAQPLQEHKQLVGDTLEDDDDEKKKKLAEQAAARTAEIVATVEALSETFVARIPAHEFSPAEIQGYLMKHKRSAEAAVAGAAEWVTETRKEKKEKELKAAEEKRAAEAKQKEEDEKKRKEEAEEKEKEAKEKRKEEREKKRKAEKKNKKSKRNKNKEAADSSDSSSSDSDSGSDSESETLAKGSEKKTAEEPVVVSGAKAEHGAEDVTQKRDSGYGTPVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAL2</accession>
    <name>A0AAD8XAL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_634515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360654.1">
        <property type="nucleotide sequence ID" value="XM_060509107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAL2"/>
    <dbReference type="GeneID" id="85393006"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="29587" checksum="1281A90F5891DC1B" modified="2024-05-29" version="1">MTACEKSGSQSMLPRGLDGKRRASCEPEPDLLSIDPVTSLRGSICNRKADRPPKPTLNNSRTLCKQLAKRHRGSNVSYETMAVSQLNREWHYCVWASQVARSQSVFGGSHRLPCYQLTSLDQAECSQVAVKEDVSHSIIVRLRFHARLRRSPQGPKGFFFKREAFLYDPAKTGTFALRQERQGQAEEREEKKKLHITSYSRPMTMAHSVSLREGEKQQQEHGAVSYQLDTGASLVDSQKAEKGSEGKGRVEQQTVCVPSARVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAW1</accession>
    <name>A0AAD8XAW1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_643513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357863.1">
        <property type="nucleotide sequence ID" value="XM_060509682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAW1"/>
    <dbReference type="GeneID" id="85393581"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146694" evidence="2">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="81" mass="8342" checksum="C90BE9FD58A50CAE" modified="2024-05-29" version="1">MHVPEIAAFALLRAGLAAAQLTYASNQVEVIPDSEAVAANFPEVEDVELRSPAFANPDSVPATFANGTSGPTDQATLGESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAY4</accession>
    <name>A0AAD8XAY4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_758861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000277">
        <property type="protein sequence ID" value="KAK1703663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357326.1">
        <property type="nucleotide sequence ID" value="XM_060515103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAY4"/>
    <dbReference type="GeneID" id="85399001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19146">
        <property type="entry name" value="AKR_AKR9A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF7">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="29"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1703663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="42566" checksum="A8D326A486D04FB7" modified="2024-05-29" version="1">MAPQLQQPLETYLARHRQLSPTAAVRVSPLALGAMNFGEKQKATMGECTKETAFEIMDHYYSQGGNFIDTANNYQAGQSEEWVGEWLASRGNRDDIVLATKYSSAYQLHDKSKLQSNYGGNSTKSLKHSVARSLKALQTTYIDILYLHWWDYSASIPEVMHSLNDLVTSGQVHYLGISDTPAWVVAKANQYARLSGLRQFVVYQGNWNASLRDFEREIIPMCLDEGMGLCPWGVLNAGRFQTEEGFKEREKHNPGRQNKVSEHDKKVSKALEKVANANGASLPDVAVAYVMHKAPFVFPIVGGRKLGHIESNIKGLGLALADEDIREIEGSHEFDPGFPHTFLSGTSLFGGAPKGAYHPRDVWLTNLMGKFDWVDAPKAISSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB42</accession>
    <name>A0AAD8XB42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_642692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000205">
        <property type="protein sequence ID" value="KAK1707740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358118.1">
        <property type="nucleotide sequence ID" value="XM_060509632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB42"/>
    <dbReference type="GeneID" id="85393531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="322" mass="36962" checksum="31271BE05135FF5A" modified="2024-05-29" version="1">MEDELNGKEVKLESLKVELQQKDADLADVRKRWKQTAKELNRLKMSQKRELYEVTDRHLVELATRLRYNVRDLAIRYFEGKMGPRGSAHELTGSKFLQYFGRVVHDTTVRNALLKSGNRRSSVMQAYLWEIFTAEIFGRYLWIGSELSGAIQVLNDHMRQARCPITSFDVESCRSFQLWSTETTGLILHTIDAKKESAVRRFIENTVRDIASGIVDAVASLIIVENDELGSEIERILHEALALDKEVCSQVARVDWITYETPMIFDPEQMEWEGEDESGRRDQPVRLVVAPALRKRGKSTGEDFDVDRLLLPMVVSRLSTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBN2</accession>
    <name>A0AAD8XBN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_640875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1709992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358688.1">
        <property type="nucleotide sequence ID" value="XM_060509522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBN2"/>
    <dbReference type="GeneID" id="85393421"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1709992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="21739" checksum="80C802CB5B81BB12" modified="2024-05-29" version="1">MLWTVSFKGFPSHQDPTLSPVYFIQMFNHNPSVGDITCHYFNNTNSVASTSTTTSTSPTSTASTLTEVFTLVEASQTASPSSSGMSNGASTGVVAGIAVGAVVGTLATIGLVGWAIWRHLRKKEKEQGHRSRVTGASDVGNFSAVQGIGPSPPVRWKHELSMDAQQPHYEADGTEGVRYEMASQSVTTNNENKGLRVKSDGMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC03</accession>
    <name>A0AAD8XC03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_584805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361702.1">
        <property type="nucleotide sequence ID" value="XM_060505797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC03"/>
    <dbReference type="GeneID" id="85389696"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF32">
        <property type="entry name" value="ARGININE METABOLISM REGULATION PROTEIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1720191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="784" mass="87415" checksum="C5B5021679148349" modified="2024-05-29" version="1">MPARPATRGSKSGVKPPPPKGKPTAKTRTTTDSAAPTKKVPRSRTFTGCRTCRSRHLKCDEARPVCSSCRRLNLVCEGYDGQLLWVPDPLCSAEQKHAHRGTSYRYPLFTEEERKTMSVEIVTSMGRQSAGDIVLDLDEKSVHRDDAHVAGPFGVFRAFDGSPDAGSSPLQHSLSESSPNTSPSDALPETVDGELDEDTEEVVIEPWSVDDNSLALEPYFLPGPFDNFSTEGMINNMSQPWMHGEGSGSLSHMMAMDNSALDLFFSPLSPRTPAMAHTELGPAEDTNNRRQNHDRVQTHIEEPASPSTDEQDLSISRKLSTPFTNNMPAIEPCLPSHAASLLRYYKTMESSSSVKGMRISPWQLWLLPCALETFAELSLWNTTSHTRHSILCTLLAKSAFHMHQSSNKESQKSTRQWLDIGQNYQKSAQSHLKMALQGESDEPSQAKYNEILMAILATAMVSVLYNGSRAVKIFLLDAERLIRLRGLAMPKSFHVRVLHHVYTHLRVIAESTDIAIDSAKSQAQAATEMAVSLRKFRIAEDSLGADLDLSREKPAEVGYADIHLDVSGHWPVTMYPEIYGVPESLMTLLSQTISFANEKTKLEAMAMYDHRISMALSRHIKQLEQNIWSWSLGSSDMQSGPSRPRELVTQETKLVDHPIIRYLTLAMHQALIIYFYRRVYNMSAMVIQDSVRKTLDFIQPCLEETADDHDFATSIGWAAFIAACEATTPDLQEMGLKVLQAIDNSGVIFGTDKPSVLAQSVWDKRTETGDWTLSWPDMMNTIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCJ2</accession>
    <name>A0AAD8XCJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ASST-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_676308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362302.1">
        <property type="nucleotide sequence ID" value="XM_060511158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCJ2"/>
    <dbReference type="GeneID" id="85395057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053143">
        <property type="entry name" value="Arylsulfate_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039535">
        <property type="entry name" value="ASST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340:SF6">
        <property type="entry name" value="ASST-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35340">
        <property type="entry name" value="PQQ ENZYME REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14269">
        <property type="entry name" value="Arylsulfotran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041899186" evidence="1">
        <location>
            <begin position="23"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="518" mass="56723" checksum="F515541150FA0077" modified="2024-05-29" version="1">MVRSTSLLKATALLGLSQAAAAQNSTTNPWPWQTYRSEPALQPPSLKITQTGDIAEGHLFFDQSGSGGHNYSVFIMSNENELIWEGPYGDISAWRAQTLFGEPVLTFYTGITMPEPYGFGYGAVFIYDQTYKNIYNVTLDQYANGLNLQTFTGWDSSGLTGGSWLDMHEDYITPEGTMFAPAVNVTQTDLTSVGGPVDGWIVDSLFFEIDIKTNEILFQWSHLDHLDEISLASAAPTYPLEDLGLNQTYPWGPFHINSIERFADGGFLISSRHYCSIFKIAKDGSVEWTLNGQTGGSFTLKNGLSFCYQHDARIHAEGNGTALISLFNNDNSGIRSGVNETSGIFLTVNTATWEATLKQELIDPNDTIFAVSQGNVQVLNDGSGHTVIGYGSTPKIKEFNAEGECVFTAQFGEDKIVQSYRNHRYPWVGKPYYAPKAFACDAGNQTEVYMSWNGATENNKWTVFAGTSEDALTEKASVEKTGFETKATFSGSAQFVRVESAGEGIETGVSEVVAVESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCZ2</accession>
    <name>A0AAD8XCZ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_584717</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361751.1">
        <property type="nucleotide sequence ID" value="XM_060505787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCZ2"/>
    <dbReference type="GeneID" id="85389686"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="597" mass="63728" checksum="F1CC849DCC87440B" modified="2024-05-29" version="1">MARAANTPTPSDDRTLVAGAHDDDDASSTISRFSSSRSSFDSQTPPRRKRPSRRAATTLRAISFVAALVSALCAGSITVFSMYGHIFQERLHYTQFQVNGLAISSSIALYLPVSFLGYICDRVGTPPLSLLAAILFSGGYAIAAGTYRKLEAENLGGLRDYAGRRIGGGADWTYPLMIFAFVCVGVGTCSMYLAAVATCAKNFGKGKHRGLALAVPIAAFGLSGMWLSQLGSHVLYERLPDGSAGDLDVFHFFVFLAILLLVVGVTGAFTLKVVDEEEIFEEAVEELERSGLLERSTSFLSARSLERSRNYGAIGQIDDEEDGGVLGPAEDDAKLRKKLVLNAETRSFLTDKTMWCFALGFLLMIGPGEAFINNLGTVIGTLYPPTMHYVGPPTSAATHVSIVGITSTIARLATGTLTDLLAPSPQTQHLQVSSTPPFLRGRPTISRVAFLLFFAIILSLGLVALASGLIQEHGERFWIVSGLIGSGYGAVFSLTPIIITVIWGVENFATNWGIVAMFPALGSTFWGLVYSAVYQSGAENSPQRGGGSGGGGDVFCYGAQCYAPTFWAMAVTVWVACGMILFAWKGKGGWAQRGIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDF3</accession>
    <name>A0AAD8XDF3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_753864</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363157.1">
        <property type="nucleotide sequence ID" value="XM_060514408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDF3"/>
    <dbReference type="GeneID" id="85398306"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041777647" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="599" mass="63730" checksum="F9EA48359E655993" modified="2024-05-29" version="1">MLQRLVVLASAVSICHATTQIVTGATLFVGDSTPIVNTSYAQFQGKNDDRTGTSNYLGIPYATAARFSHSVLAETVVSGVQNVSAYGAVCPQHELPSSIDPSVLPLGSLSGTLVAALSQSTLEQGEDCLSINIHVPQNTSSTAGLPVLVWIHGGGFEAGAGGSLMQADVENPGVVYEAANVVERSVAMGQPIIVASINYRLNHFGFSASEELATAGLLNLGFGDQRNALRWVNKHIGSFGGDADKVTIWGESAGSWSVAAHLVANGGDNEGLFRAAVGSSGGPLKVDGPARQQETFDSLASYVGCSDAADVIACLREASYDDIYAHMQTVPYFLGYNSLASSWTIRPDGEVFTDSPDKLVSAGAIADVPLLWGDMRDEGTLFSLVNAANTTTDDEVMDYFLRTWWPNATDAQLEQILTLYPANQTAGSPFGTGESNALYTQFKRISAITGDYSFESQRRQLLDAAPGTKWNYQVDQALPAAILDGSATLGAVTAADYADASVLEAIPYLGSFHASDVVLNFFGTLPANNSRHMMGTLIAFVNNLDPNKHDMSDVPTWPQYESTSRSTILWSEAGAEIVVDDYREEAIAYLNEIGESLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDN5</accession>
    <name>A0AAD8XDN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinetochore complex Sim4 subunit Fta1-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_581171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363367.1">
        <property type="nucleotide sequence ID" value="XM_060505432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDN5"/>
    <dbReference type="GeneID" id="85389331"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025204">
        <property type="entry name" value="CENP-L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13092">
        <property type="entry name" value="CENP-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="423" mass="45524" checksum="B5A8F9F1AC2483AB" modified="2024-05-29" version="1">MPPRGRPRAAAAESDSEVLPDRPSPSSLEDREPPPPFFNTTFSTHRASPLYVGANTLSFPQLQALSQRLRDTLVGDVVRGVQVGLEGSDSSLGRAGPLEKVGIRWVGVEALLGGADDTDPDLSRDLGGDAIETDDAVRKKRCLIFEMRYENALCTAVLLPSISEKTAEESTAGLQSANSLGVPGLLASSGSKDDRHFLHLPLLLLRMPAPLKSVIVDFLSSTFDCRISPLRLGTKGLTTAWERWIEDAGLPSQGPLAKDMVLTLGFYIPPAVTTDGTDEQPPDGLGIKSIDIIIPAEELKRFAKEGRSLTNPVATNKAGLTQGYQDDPRKRKKLAGGKANEGWGWIDGQGQHEEAFLHALGAYLEKHLALNLFHPGVRVTKIACGGFVLSEGRVKVFVPPGDDEEVFEPVKHMISDLIASANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF76</accession>
    <name>A0AAD8XF76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_317148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365107.1">
        <property type="nucleotide sequence ID" value="XM_060502344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF76"/>
    <dbReference type="GeneID" id="85386243"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03751">
        <property type="entry name" value="proteasome_alpha_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000044">
        <property type="entry name" value="Probable proteasome subunit alpha type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32078" checksum="A2CD6AB9BCCF93ED" modified="2024-05-29" version="1">MTSIGTGYDLSNSIFSPDGRNFQVEYAVKAVENGGTSIGIRCKGGVVLAVEKIIASKLWKPNANKRIATIDRHLGVVYSGMIPDGRHFVDRAREEARGWRDTFKTPISTADLAARMGGYLQAYTLYSSVRPFGITAIVGGFDPSTETPVDGEVGSGPKVGAGGKDTTKKHGGPFLYMIEPSGLYWGYYGAATGKGRQAAKAELEKLDLADGELTLEDAVKEAARIIYVAHDDNKDKEFELEMSWISDIDGPTKGRHEEVPKELREEAERFAKKSLEGDDDDDEDKKEDDKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFP1</accession>
    <name>A0AAD8XFP1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_622440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364631.1">
        <property type="nucleotide sequence ID" value="XM_060508333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFP1"/>
    <dbReference type="GeneID" id="85392232"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041917846" description="Trehalase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1724576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="680" mass="76089" checksum="6F9BE79AC0EADDCC" modified="2024-05-29" version="1">MVNFALALAAVAVLPRTAQALYENGSVIAPCDSPIYCHGDILKEVELARPFSDSKTFVDMPAIKSLEEIQAAFNNLSKPLSNNTALNDFLRANFAAAGGELKEVPKDQLKTDPKFLDKINDTVIKEFSQKVIAIWPDLTRTYAGSASNCTTCPNSFIPVNHTFVVAGGRFREPYYWDSFWILEGLLRTGGAFTEISKNVIENFLDLVEKLGFVPNGARIYYLNRSQPPLLAQMVRLYVEYTSDRSILERAIPLLIKEHDFWMTNRTVEVNRNGTIYTLNQYNVTNTQPRPESYREDYVTASNASYYSTSGIIYPEVEKLNDTEKARVYANLASGAESGWDYTSRWLSRPADAARDVYFPLRSLNVLETVPVELNSILYWNEMTIAALLNSTNNGTGAVAWTELATKRSQAMYDLMWNSTLSSYFDYNVTSGGQNIYIPKDDDASTLETDTAEAEQQVLFSVSQFYPFWTGAAPSHLKNNPYAVKQAYQRVEKYLDIKKGGIPATNLKTGQQWDQPNVWPPLMHVLMEGLRRTPATFGESDPAWRDVQSLALRLGQRYLDSTFCTWYATGGSTSETPQLQGLTAQSVGTMFEKYGDNSTNVAGGGGEYEVVEGFGWTNGILLWAVDVFGNDLKRPDCGNITAANIHPAKRSLPQRAVELDSYDASWIKKFGRRAEEAARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFU8</accession>
    <name>A0AAD8XFU8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="15">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_697019</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366294.1">
        <property type="nucleotide sequence ID" value="XM_060511377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFU8"/>
    <dbReference type="GeneID" id="85395275"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000040">
        <property type="entry name" value="Calcium-transporting ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006413">
        <property type="entry name" value="P-type_ATPase_IIA_PMR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01522">
        <property type="entry name" value="ATPase-IIA2_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 15" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="917"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="951"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="988"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1020"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="60"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="183"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1726239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1058" mass="114940" checksum="826380AE4CCF18A5" modified="2024-05-29" version="1">MQWPWHKRKDSNDGEALLPLAAKMPSINGLTMEPMETESSRSRPGHIRTTSAQSRSTADEFSWMSSAEAASRLQTSLTHGLSPTEALTRLSDYGPNEIPHEPPEPLWLRFIKQFQEPLILLLLVSAGASLFLGNMDDAVSITVAVTIVVSVGFVQEYRSEKSIEALSHLVPAHAHLVRSAISKTPGSAKTPTWPPQGPMDGTESVGSTTPGEEMLEATSSKVMASQLVPGDLVYFTTGDRIPADIRVTKAADLTIDESNLTGENEPVRITAETKARSLLSPAYGADTLQLPSPSALSDNRDAGGSGENNIAWMGTLVRSGHGQGIVFATGGQTNFGTIATSVSGTESPRSPLQLSMDDLGSQLSKASFVVIGLISLVGWLQGKKLLEIFTISISLAVAAIPEGLPIIVTVTLALGVHRMARHNAIVRRMPKVETLGSVNVVCTDKTGTLTMNHMTTAKMWYFGTNDAIDVESDDEATETKPDPATLRILRIGNIANNGRLAQQYTENGAAARAVLSSTQGADFTSTYTRWCGQPTDVAMLDLLDRFKEHDVRESIGPRLTETPFSSERKWMGVTIGTNDKEFAYMKGSIDRILEACDTYLTRDGREIVLDSTRREEALQAAETMASKGLRVLAFASGAVSRSRGRAALAPTSRTNTPQPVDETYRGLTFAGLVGMSDPPRPGVGKSIRRLLRGGVRVVMITGDAETTAVAIGRQLGMPIAKPIEYASNQAAVRPVLRGEDVDNMSEEELSHAIQHTTIFARTNPDHKLKIIRAFQARGDIVAMTGDGVNDAPALKRADIGISMGLHGTDVAKEAADMILTDDDFSTILRAIEEGKGIFNNIQNFLTFQLSTSAAGLSLVLICTILGFKSPLNAMQILWINIIMDGPPAQSLGVESVDADVMNRPPRKRNDAVLTRALLYRVMTSAFIIMAGTMLVYRREMLADGEVNRRDTTMTFTCFVLFDMFNAMACRSESKSVLRGEVGLFSNTLFNWAVSLSIAGQLLVIYFPWLQEVFQTEALGLFDLLGLLVLCSTVFWADEFRKYWKYARRRMGGGYSQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGF6</accession>
    <name>A0AAD8XGF6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_649862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367074.1">
        <property type="nucleotide sequence ID" value="XM_060510322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGF6"/>
    <dbReference type="GeneID" id="85394221"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="17481" checksum="01A7887405D99C1D" modified="2024-05-29" version="1">MAKYHEILKDELSAWNQNALSSDLWQGISEERKRKETKMKEEAFDQRLFQRKTTGGMILVNLKKDPKANPDYSHAKAPTGQTSPMTHLAAEWKNNNDDAWERNVITIEWFCSIPFPNRTNEDEIKLQESPRGKMLQSYADQYFEDNIVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGQ6</accession>
    <name>A0AAD8XGQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_582348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362800.1">
        <property type="nucleotide sequence ID" value="XM_060505544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGQ6"/>
    <dbReference type="GeneID" id="85389443"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053144">
        <property type="entry name" value="Acetyltransferase_Butenolide"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43233:SF1">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="20276" checksum="33F5ECC4A47F80E1" modified="2024-05-29" version="1">MPNQISKQWYKDEYLISTDRSLVDLNAVNDAFDSELLWWTKRVPEVALKRLIDNSLCLGVYKLPQSTADIAGKKGPELIGFARIVTDYATIGYLADIYVLPTHQGKGLAPWLMQCLNEILDEWPDLRRFLLLTSSPQASKLYEQALGTTEWGVSHSGKLYLLEKRGRAMPSGPSDGEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH16</accession>
    <name>A0AAD8XH16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_718781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366056.1">
        <property type="nucleotide sequence ID" value="XM_060512111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH16"/>
    <dbReference type="GeneID" id="85396009"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF241">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="134"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="206" mass="22615" checksum="76ACE9947A8B559C" modified="2024-05-29" version="1">MATQYEVEHNIKPGPSTQDGTRRIDMSSFTSFLSNLTTDNHSATAAAAAAAHHNPHATPTPVDAAALYTLLQQQFQTLFSTAPNTQNAAFLSSLVEALESDIVSPPTEIPGVSHEYLDSLDRVPKKSIKEDEACPICAEKFLDDKYPLVVELPCHSSHRFDLECVSPWLRSKGSCPMCRKDLTKKKEPVVVVDDDEENDDPDGLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI48</accession>
    <name>A0AAD8XI48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_576251</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365633.1">
        <property type="nucleotide sequence ID" value="XM_060504904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI48"/>
    <dbReference type="GeneID" id="85388803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000016">
        <property type="entry name" value="Putative ubiquitin thioesterase otu1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OTU" evidence="13">
        <location>
            <begin position="120"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="75"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="43119" checksum="E3A0B4242D8561C4" modified="2024-05-29" version="1">MRARYKGPGGTGVVSLEDTATVGDLFKEIKDKTGIAEFTLKYGWPLQTLTLEHKDANAKDLGLNGQSFSIEPAHHRAITPPPAAPAARGPEASKKPRLDPDADPSPSDISIPWPERESTLLLRVMPDDNSCLFTAFGGAIPGKQMEAKELRKMVADYIRQHPDDYPEAVLDMPVEKYIRTIQDPERWGGAIELGIFSDLFDLEVVAFDVKSQNPLRFGENKESRCILVYSGIHYDRIACSPSEPPHYSHSDLPPELDRTNWSTADDEVLDRTRALIRKLHEMHYFTDTTEFLLRCTVGGCDWLGNGQREANKHAKATGHMGFSEIKDEPAGGGGGAFGGSSAGGAGGVASVGGAGGAFGDNALRKCDTPGCEWLGSGTAEARIHTGATGHTAMTEIPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJH1</accession>
    <name>A0AAD8XJH1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_718337</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366610.1">
        <property type="nucleotide sequence ID" value="XM_060512058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJH1"/>
    <dbReference type="GeneID" id="85395956"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1726555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="546" mass="62886" checksum="59A7F135765C6246" modified="2024-05-29" version="1">MPAKSKVSSKAKEAEGKSKQTPSSSSSTAAAAQEPPKTVNERSLHRFYQTNPHERKREEAGGLHSLTPAERQAWVNASLVRRVASKEICLNNKAEREFWKQVNRESPPIRRLDRQKTQADKSTGTGTAAVVYDWGRDKNGRDVGEYPLEQFAARAAKQAQLTALEVLHRRFLQRREFASAEVTDAATGKVEEITKEDIQEETQRRREMSAIRKELYGDKMGPYATDPEWDDVMPIPAEEPEGALATIAYPEDYAEVMSYLRAVMVSEEYSPRCLRLTEHVISMNPAHYTVWLYRFKIVRALETPLADEIEWLNEVSLEHIKNYQIWHHRQLLLDHYYEGIKATPDEVKRFGRSETEFLTRMLEEDTKNYHVWSYRQYLVRKLGLWNLQELLSTQNWIEEDVRNNSAWSHRFFLVFSDPANSTEGSHATEHDPKVPADVVDREVRYVEEKTLLAPQNQAAWNYLRGVLVKGGRKLETAEAFAGQFVKNVGAEEEEEVRSSHALDFLAEVLAEKGQKEEAAKYLDRLAAKWDPVRAGYWKYRKQQLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK02</accession>
    <name>A0AAD8XK02_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_112818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368620.1">
        <property type="nucleotide sequence ID" value="XM_060501104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK02"/>
    <dbReference type="GeneID" id="85385003"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="28431" checksum="A6F4609EAB0EF81D" modified="2024-05-29" version="1">MESGDSGRRALSQVVVLRLSFRRRLLSFCAFSAVRDTYLTIRDRLQTAESRRRFVVEFLLLRHFSSLAFPVTENTNRHTEYTVHRGRKRRFSLRNTTFSRPTDQPTNRPTDQAIRSTMAANRVACTAARSLGAPKSQAAASQVRMMSSAGRSNGTSQCWANCLSTAFKKFCLLQVGVCYPALSPSQALFLSFMRVRGWCSSKLSQARFSSTAQTGQLPSKLPYAFLPHLFCSPAYTARHASLFAILHRTNGQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKG7</accession>
    <name>A0AAD8XKG7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_90067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1729015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369070.1">
        <property type="nucleotide sequence ID" value="XM_060515991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKG7"/>
    <dbReference type="GeneID" id="85399889"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="93"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="317" mass="35891" checksum="C897B7954857A5AD" modified="2024-05-29" version="1">MNPLPDVIVIQDPPPEFAWKSCPGYNPEYLPARELLEKDNPKTTEDPFPVKLVGFYVTKSIDPSDWRIDWREHDNDHYGSVASLFLNTSCGEITIHNVYNNKQSISMSKLLTASDHPVTGESAVLIGNFNLHHPEWGGDRVAQVEKDAGILHQATSMAGMRCLLPPGLRTYSRSATDTGDFSTTIDLAFAAQRLESRAHPTRVLSVPGFDSDHRPLHTRISIAPNRDKEPRFNWDKANEKKYCEEVKKQLLTIGCPTIRTAAEVDDYAKALVLAIYQAVRRTIPCYRKTAPRPKPEMDPEDVQRARENEKNQHRILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKQ8</accession>
    <name>A0AAD8XKQ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369221.1">
        <property type="nucleotide sequence ID" value="XM_060513642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKQ8"/>
    <dbReference type="GeneID" id="85397540"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="15"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="63049" checksum="9A9495FF9053A7C4" modified="2024-05-29" version="1">MSQPPPLQQQQQHQVLHINMLPAEILHHIFSGLEPRDLGRLPRTCRFLHSYVKGNQKLCKDVYLNALDTPKQTGLDWERELHDFVRLGLVCAGDSVNEKSRDLLPFVSDVVNRLLQHASPTGETQNDTGTHAVSRNATALARFFHEEPARVAFLCRSHIFDRARGDAARPTSSSRRLQSSSSSASSSSRTDPTADDIHQQSAKLHCLYGRPIFNTGRTRSSRVYPYAACKVYDMRQYTTRTKWGPFRDDDSGRVDWEKMEAIMIVLGSNIRSQRLTAKVFSNLWEKPFAGSWSGSYVPSPGRGIRDLDLEDPYGVAGTWLRVVCFIDYNDFFHYNFPIGEEPPPIEVQRPPLDVGEATRIILMKMFVVDVQPPGEDDGKELPVVHFHGLSRSVDDSWDENAHSQLRATEGTVRMTKEGEVRWTTFSVFNGHARWRSEGIQIGGVGSARGVMGHWFDTDYDPHGPCGPSAYFKVSDRAPGPKEGDDNKIDIHDFLPIMDFDAELASNEDDDEDFVVGEWGEDEDDDGGEIDDEELVEDLAALAAPDSELMDLVLSGHHLIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL11</accession>
    <name>A0AAD8XL11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WLM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369386.1">
        <property type="nucleotide sequence ID" value="XM_060504096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL11"/>
    <dbReference type="GeneID" id="85387995"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053136">
        <property type="entry name" value="UTP_pyrophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30399">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YGJP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30399:SF1">
        <property type="entry name" value="UTP PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="10"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="516" mass="57380" checksum="D81C2EAF13A88165" modified="2024-05-29" version="1">MPIGIQRLNAKRSHPNDRIIFIKPLKGRDEKVAQDFLERIAAQCLPIMKEHHLSVMSLEQYEFNREFVGRNFNAGEIIQLVLKSQSGRWLPFEYVQMVMMHELAHCKQMNHSRAFWAVRNNYAEQMRGLWQRGYFGEGIWGRGALLGTGQFQNNVALPSEPLPEHLCGGTYRSRGRKRKIKPILSYKEQRERRILKKFGANGTALGADEETKVKLEGGKRTQAKPRVAGSARGRELRAAAALARFDQPKKEPEEDIKNEVKDEDSGESEYEDDPADIKNEDAVDIDGKVIKDGKGRGMIKVCEDENPDDQDAQNELQELQASVKQWRQTHLEFKREPVNEAEVAAVPPQNQAAESSRKQEPMIRNPKQESPPRVKVKEEPNDDQEAPILDIASTTPTIKREARDDPRSIATSHPTSPPSASSTASPSAEKQRATATATESATMTAPNEAESICGVCSFANSALSITCAVCSHVLDPASVPNAWRCEGAACQGSEYLNPGDFGVCGVCGHSKRKKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLA2</accession>
    <name>A0AAD8XLA2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_605109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369502.1">
        <property type="nucleotide sequence ID" value="XM_060507316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLA2"/>
    <dbReference type="GeneID" id="85391215"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000828">
        <property type="term" value="F:inositol hexakisphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="5">
        <location>
            <begin position="366"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="405"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="232"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="45361" checksum="65C4D83CA26D9000" modified="2024-05-29" version="1">MDRPNFNTRRSVDSARTATATTPASPAAANAAAPASPLNPHFSQTSSSSSHSTVNTSAPTDVPLRSRPGRSVSHSLNLSSSASRKSRHAEPGTTDAHSASASLSMPPPSSIPLKSPRTSLCRTRRESNNSLEAWSDSALQFADVDEVDNTPRLMSGSSQQDSTAPYRPLPEPALTSRSSFSSESDLKDKRTSVSSIFSVYSLASARGAAPTSVPATQSSAASTNGSDGGPSRSVSGIMSSGKPVTNASQPGAELSNVTVTTSSNGQNANAAPGGHHLAPRETNTHTHHEVIKRPPRPAQPTRSRSRNKRRFSGSTGASSHSPSSDRGPYHNKEKEEGQSRDTSAPRQRVPTSSNAPAVKPAPWGVIGVCALDVKARSKPSRNILNRLIANREFDVVVFGDKVILDEGKPPFSPMERRNPSSERIRNPEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLE8</accession>
    <name>A0AAD8XLE8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_647853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369627.1">
        <property type="nucleotide sequence ID" value="XM_060510120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLE8"/>
    <dbReference type="GeneID" id="85394019"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="40470" checksum="B9FFD29C338A35E8" modified="2024-05-29" version="1">MYTRLQHFADAVYKRAVEETPREPELPGWSFWVFLADFIVFLPIILWTSYTLHQVYPIFAIVEDENPPAYDPVNLAEDEGAIPSAGPEVRPDGPVPQTKVTGGRPTTVTSSIRSINRLLTTYGGWRSNFRGFGVYFVQALATNFLFGIFSSFLPDILASLATLLSALALVQLSAVWVHIVITPSSSDYFWKRLPPFKRTFDATAKPVAAYWLAEQVATWVPIAVGWALGLDLPNFQFGKPNSVVSQPQSSDAWKSIVITLISIAFQIIIVIPAHVVLVRVQASLIPEEANTIIPFDRSFKGKVEPRVVGGKGYATMDDAWSGFSRNAWKRLVILYVKIFAVSFAAFALMAAVVIPEIIVFSKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMB4</accession>
    <name>A0AAD8XMB4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_747705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370122.1">
        <property type="nucleotide sequence ID" value="XM_060513489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMB4"/>
    <dbReference type="GeneID" id="85397387"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042015685" evidence="3">
        <location>
            <begin position="17"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="152"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="673" mass="72379" checksum="33C8C37F31037FE7" modified="2024-05-29" version="1">MKFLFSVAALFAAAHAAFDQPLGPTLNATGPSANSTYDYVVVGSGPGGAPLAARLAMAGFSVLLIDAGEDRGEDPAVQVPALHVLASQHQPIAWDFFVNHYSDPEQAKRDSKMSYRKPDGEIYVGLDPPQGSEQLGILYPRVGALGGCSQHNALVTILPQDSDWDNIATITGDSSWEASNMREYYKKLEKCHYLPGGLDNSVHGYDGWLETQTTPPILIVQDQKVLSLVLAAATTMGKSLLGKVINTVTGLLEILAVDVNNDSPDRDSGEKIYQIPLSMKDPSFTRSSPRDFIFDVVTATNDDGSKKYKLDVALNTLVTKVNFDTTGEKPKATGVEYLVGKSLYRADPRATKEDGGVPGRVFASKEVIVSAGTFNTPQLLKLSGIGPASELESFGIPVVKDLPGVGGNMQDRYEVGIVGKAPTDFSLLEKCTFLDMNGTHNGEDPCFSQWQSGIGGLKGGYTTNGIAFGYFKHSSVAENGNPDLFLGGVPAYFNGYFPNYAEHALADLSVWTWLTLKGHSRNNAGVVNLTSTNPRDTPNITFHSLFEGIGGEEDLQAVYEGMQYGIEAFENLIPLDGSFERIWPPKEISSEADLKQFAKDEAWGHHASCTAPIGADDDPLAVLDSNFKVRGVDGLRVVDASIFPKIPGFYIVLGIYMASEKAADVIIAEAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMN5</accession>
    <name>A0AAD8XMN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_602132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370317.1">
        <property type="nucleotide sequence ID" value="XM_060507147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMN5"/>
    <dbReference type="GeneID" id="85391046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="307" mass="32234" checksum="82E0297038257D9C" modified="2024-05-29" version="1">MEAARTAVAPTTAVAPTTAVAPTTAVVPTTAVAPTTGVAPTMAAVPEETAVAPTALLPPAARAPEATASTAATALTTTPRPVVVPLPSPVSPVLPVLAVLLALPELLVPAVPLVRLALPVPVVPPVELPLSLALLVPLARLVLLAPVALPVVLEVLEALVALPASLALAAPAAVPLAQPPRVVLPAPRRPQSRSPRHRLSRRASASFAVSQWLPALPSLLKTTTYSLVFFFPIMQSPHSQNAVCSRPQRSKEEGKKEKKGVKEKRVQIGNTVLFGSLFLCKPLFGYNSREFFSISLIHERKLSFCFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMU0</accession>
    <name>A0AAD8XMU0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_401937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370395.1">
        <property type="nucleotide sequence ID" value="XM_060502852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMU0"/>
    <dbReference type="GeneID" id="85386751"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="27850" checksum="980AD6AB0E5A0077" modified="2024-05-29" version="1">MMTGCGAGVQARGNLYPHSTGCCARVCLSRAGLGSLPFPPCRSTYLTDTRYIGCYHSVRTWEIPRHLSRKAGTQEGPSWSCHPASQLSAPAAPGVRWLFPGLPVRCPPPSPFRAGTQLHSQCPVVTEVTPFPRRNSLMLDSKFEGTGRSFSQLITTKPAALGPDDRTIASQPHIFLPVLFGQPTGCLWETTKAIALHCRLPTSNNKQTSPGFPLHLQPCSPCVVHLRIRTPPFFLFTNAPVCRTECLFRKTEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMU7</accession>
    <name>A0AAD8XMU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein SEC22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_747523</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370358.1">
        <property type="nucleotide sequence ID" value="XM_060513449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMU7"/>
    <dbReference type="GeneID" id="85397347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15866">
        <property type="entry name" value="R-SNARE_SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000007">
        <property type="entry name" value="SNARE complex subunit SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000014">
        <property type="entry name" value="Transport protein sec22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="16">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="17">
        <location>
            <begin position="134"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1730303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="215" mass="24963" checksum="362C8B965EC9785E" modified="2024-05-29" version="1">MIRSTQIARLDGLMLCASVDDEQQEAALSEVKSQIKQVLRKLTRNSEPQASIESGAYNLNYLMDSDITFICITDKSYPRKLAFTYLSDLAREFTTTYPVSQLHSPSLRPYAFMEFDTFISRTKSTYSDARASQNLDKLNDELRDVTKVMTKNIEDLLYRGDSLERMGELSSRLRDDSKKYRRAAVRINWELLLKQYGPLGALGFIVIVFFWWRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMV2</accession>
    <name>A0AAD8XMV2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_602447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370407.1">
        <property type="nucleotide sequence ID" value="XM_060507170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMV2"/>
    <dbReference type="GeneID" id="85391069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="192"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="270"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="342"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="44939" checksum="5C17BC3D8E49A0C2" modified="2024-05-29" version="1">MDDPSSSSSSSASKDNAGPGSMPTSHPSQQQPSGNGPLQPPVVATAASIARPHGHELPFVTPSSYLRPRPPSVARKMPEKPPSPLDKDQIQGLRAIRDFLKVRTSYDVLPLSFRLIVLDNDLLIKKSLNILIQNAIVSAPLWDSHNSRFAGLLTATDFINVIQYYCQFPDEMHKLEQFRLSSLRDIEKAIGASPLETVSVNPMRPLYEACRRMLKTRARRIPLVDVDDETGREMVVSVITQYRILKFIAVNNEHNTVLLKKSLREIGLGTYKDLATAQMHDSVLSVVDLMVKQNISCVPIVDKYNRLLNVFEAVDIIPCIKGGVYEELQSSIGEALVKRPDDSPGIYTCSPEDRLDSIFDTVRKSRVHRLIVVDDDNRLAGVISLSDILKYVLLHGEEDDVVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNV8</accession>
    <name>A0AAD8XNV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine-threonine protein kinase 19-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_336208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STK19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370859.1">
        <property type="nucleotide sequence ID" value="XM_060502450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNV8"/>
    <dbReference type="GeneID" id="85386349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046579">
        <property type="term" value="P:positive regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018865">
        <property type="entry name" value="STK19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10494">
        <property type="entry name" value="Stk19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="416" mass="44560" checksum="6F261D6025BF864A" modified="2024-05-29" version="1">MSLRSILSGGRIKKPKPKPKPSASPRKNSGTSSPRKSAGGSSSNAKRNTTTPSDVQDDDGGYDDDFFHDRLDDAGLVAALATDMSLRDVVQAIKYTRSRMFGPVPTEAAGMNSTRIAEVLNYRRAMPGIVTTSHLHALLASPTAVEREVAELQRGGALRKIYVQRRGGLGEALIQTSELEDMIAKSAELDDDARSAYVKFLRENPLAQTMPRLACGGHKQADALVRAGFLTSSIHPQHVNTPLMNLHLRPEDRGSLMSIQAVSRAASGSFDAVGGQGGIHAAGGGGGAPRLSRGGGTADASSYSGAEFTIAVPGNGSFLKLTAAAVEHLAHLLSKSQFREMPVSMLRERWEGGVARDEARLARRARGEFAGVLPGRTKRWKEFYGLEFNWVLEEAMGAGLVEVFETRSVGRGVRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNZ5</accession>
    <name>A0AAD8XNZ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_600626</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:18865"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="2.3.1.168"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:18866"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370843.1">
        <property type="nucleotide sequence ID" value="XM_060507045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNZ5"/>
    <dbReference type="GeneID" id="85390944"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043754">
        <property type="term" value="F:dihydrolipoamide branched chain acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000013">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.320.10:FF:000002">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="46"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="13">
        <location>
            <begin position="195"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="136"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1730788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="511" mass="55212" checksum="57FA5793ABDDA30A" modified="2024-05-29" version="1">MFLQRGSRAVRTQWHVSKSMARLAAARAAGVYPSRRFHDTRHLRVVKPVLLADIGEGIVECEIIQWFVEPGARVEEFSPLCEVQSDKASVEITSRFSGVVKKLHYDAGDMAKVGKPFVDIDIQGGAKKEDLDALTAPTEAVQEKPSQKTPEPPAQPKTQQEDKTQDQTRRESGVASQDAVSAEDTPRPKGTHASLATPAVRHLTKSLNVDIAEINGTGRDGRVLKEDVQNFVKRRDAGDRPAGAATPSPAAAAPPSGAAQLETRVPLTNTQQQMFKSMTRSLAIPHFLYADEIDFSSLVQLRTRLNRVLATSPEVGGGETGVAKLSYLPFIIKAVSMALYQYPILNARVDLDPSSSPSSKPSLVMRSQHNIGVAMDTPAGLLVPVIRDVGSLNILSIASELTRLQKAALAGKLAPADLKGGTITVSNIGNIGGTYLSPVIVDKEVAILGIGRMRAVPAFEGEDSDRVVRKHVTNFSWSADHRVVDGATMARAAEVVRRVVEEPDVMVMHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ80</accession>
    <name>A0AAD8XQ80_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_736880</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371579.1">
        <property type="nucleotide sequence ID" value="XM_060513010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ80"/>
    <dbReference type="GeneID" id="85396908"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000211">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="6"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1731524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="460" mass="49827" checksum="67736904CC7CBE63" modified="2024-05-29" version="1">MGKEEKNHINVVVIGHVDSGKSTTTGHLIYQCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAAGVGEFEAGISKDGQTREHALLAYTLGVKQLIVAINKMDTTKWSEARYEEIIKETSGFIKKVGYNPKTVAFVPISGFHGDNMLAPTTNAPWYKGWEKETKAGKSTGKTLLEAIDAIDTPKRPTDKPLRLPLQDVYKIGGIGTVPVGRIETGVLKPGMVVTFAPANVTTEVKSVEMHHEQLTEGLPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPLGAASFNAQVIVLNHPGQVGAGYAPVLDCHTAHIACKFSEILEKIDRRTGKSVENNPKFIKSGDAAIVKMVPSKPMCVEAFTDYPPLGRFAVRDMRQTVAVGVIKSVEKSAGNAGKVTKSAAKAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQU3</accession>
    <name>A0AAD8XQU3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_786952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371831.1">
        <property type="nucleotide sequence ID" value="XM_060515655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQU3"/>
    <dbReference type="GeneID" id="85399553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="56486" checksum="34046AA27E84232C" modified="2024-05-29" version="1">MVGQITYTEEEIIFILNHSLSKGKNQTDTLREYEQRFSKTLTMAQLKYVRAKYGHDPEFGTAMINGQVPDNGGNRKTAVPSPWQEAMATPVQYENDQNNQTFTSSTNEDDSSLENHMLQALASYVYDSPSETPENLALSSEKVQQQDEQARIDAEEYAAAHEKILQMFQEHPDRPYGVQPVQQYYEQMLFPSTVQKRKRNELEEASEQPITAPDSRSSLSVLEIPHESIPKRLKTQLRETSSQNAPAQYSSPIPNNNASHTVGHGDEALSLLNVDLPEVPGTPDNLEMGADYVHAERDHSVSPLTKLLNSIDNEYAQGTTTDSSVFTQLNHQMDPSGHNVVNFENDMFQEPNLAAAPLWTEANSTMFSANTSLNFSHLMPHAPWEAPYNEEESNFWGTQSDNWQSATGYDTALGFDFDPLVPQYPQASAPYAYAGMMASAGETYHGSEAFTSMQQQAEGQNAAGFSGDISIDWNNVSKADWEELFMSSAEPQGHADYSQQFFGPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR70</accession>
    <name>A0AAD8XR70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 28 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_564319</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371994.1">
        <property type="nucleotide sequence ID" value="XM_060503629.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85387528"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000100">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="3">
        <location>
            <begin position="142"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="4">
        <location>
            <begin position="476"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="684"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1005"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1121"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="703"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="787"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1212"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1233"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1299"/>
            <end position="1308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1321" mass="143288" checksum="CECD1A4F0B8C3CBE" modified="2024-05-29" version="1">MTVVKNSEAGASSSAPPPPPRRPSDLNLDRTDSAEVPDALVSDGFSLPSLEAENEAPPAYGDLPDQLQFNQAGFEAGANVTGDGRVNININQSGNRLAEILAPTLRNQLLADKRPQAPLPPAYIPPSLGGQPGQTPPPQLNVVIQIVGSRGDVQPFVALGKVLKDTYGHRVRIATHATFQKFVEENGLEFFCIGGDPAELMAFMVKNPGLMPGFDTLKSGEVSKRRRGIQDILLGCWRSCIEAGDGLGPPPKPHAKDQPLDEHYGIPGDPTQKPFVADAIIANPPSFAHIHIAEKMGIPLHLMFTMPWTPTRAFPHPLANIQSTNTDTVMTNYVSYALVEMMTWQGLGDVINRFRDKALDLEPMSLIWAPGVLTRLRIPYTYCWSPALIPKPNDWGREIDISGFYFLNLASAFTPEPDLAAFLAAGPPPVYIGFGSIVVDDPNALTRMIFDAVHQTGVRALVSKGWGGLGAEDVGLPEGVFMLGNVPHDWLFKHVSAVCHHGGAGTTAAGIQAGKPTIVVPFFGDQPFWGAMVSRAGAGPDPIQYKELTGDKLAEAIKFAIKPETQARAQELGHKIREEKGTDLGGKSFHDHLDTDELRCSIEPSRAAAWRVRRTKVRLSPMAAAVLVERGLIKYSDLKLYRPKEYITEGQPWDPISAVSTSLVADLSSIGMAVADFPRELFKSRSKGDKTPEASTPSLTEASSSKQSLHQSSSKQSLHQSDKASIAAPSTHASESSTQLGLMEMEGSTPTLPQSPQPDTASLTQSQTASTAPSMVFSPPDGASIARSETTPSEHASTTQSVRPPNSPAKRSFKESMPANVGVDAAVAAGTSVSRIVTTGVKTPMNVCLGLARGFRNAPRLYNDDTVRPPEKVTDLASGIRIAAKEFGYGMFDGIGGLVTQPLKGAEKEGGIGLIKGFGKGIGGLILKPASAVWSVPAYTMQGVHATLRNAFSSSVQNYIIASRMKQGQMDMDSASVAEREDVVVRWNNVKFDLKNFQAMKLKEQREKQRAEGEGPYGQPEKSLTAPVTGWAHTRKLSFEERKQLHARKEAWKKGHVEAIVPASRSDLSLSEPTSTSAAEDEEFERAIRVSVAETSRGNAEEDAAVEQAIRASVNHFRSSGVPDIRAEKAAPLDRDAKNQDQDPFTSAELEITDEEYQRLIEEAINQSMSLKAAGVQPGEGSHGDDEEFQRALEQSRIAQQQPPAHEDDEELQRILEESKRQHAEGNTNEEEELRKAIEASEAAHREQQNKDAAARTEEDVVMEYVKKQSLAEEEFRRNASKGKGRDVAEDADDEEDEELRRAMEESLKMSGRPGGSSSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0C7</accession>
    <name>A0AAD9D0C7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369948.1">
        <property type="nucleotide sequence ID" value="XM_060510077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0C7"/>
    <dbReference type="GeneID" id="85393976"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="155" mass="17358" checksum="AE51417A337415EF" modified="2024-05-29" version="1">MRRGRISEQGPGDVEDDCEGSSSSELRVEGGCELTLIDRTPLARYWMPHHFSMNRGVSRAIPDPKPLGQTTFECSHSKTWSGLAPVTPTPRLELRKDEGQWPICRLSRSLEFDTLVLSKVSAVALVALVTCKFPLSGVLGKRQKPQRRLETQWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D253</accession>
    <name>A0AAD9D253_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MIF4G like-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_647057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370341.1">
        <property type="nucleotide sequence ID" value="XM_060510038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D253"/>
    <dbReference type="GeneID" id="85393937"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000079">
        <property type="entry name" value="Related to cap binding protein 80 (Cbp80)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000035">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000045">
        <property type="entry name" value="snRNA cap binding complex subunit (Gcr3), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G-like type 1" evidence="2">
        <location>
            <begin position="331"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="3">
        <location>
            <begin position="538"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="800" mass="89983" checksum="9458321D9F0BFB0C" modified="2024-05-29" version="1">MGDYERRRYHGGGGGGGYNNRKRRYRDDDDNDHRQSRRRIDTAPLPVRVRRQLLSLAESPLRRWHEEVQGIAHVVAENAEDAELRESFVSLVLQLSLEQPLKTPFVAGVVLLVNTLKPEIVDEVLTKLSAATQEKIQAGEWRDVKLYLKLLACLQSSLDGEGIFPVLEELFGRAVDLQTASSDDTIGTELVKIILLTIPYIMSAAPDQWLQKAADLMDKTEIIASEPHALQALIDPYLPEKQDQPTGSMSFIGMLQKQLQHEAANGWGLSCLPRPWKLPLEEIEAQEKLDNATKHTLPTITVPEKIVAGSRPLFPEVYYSVYSTQDVESVPPVTDIAASLVRDGLVDTINILDFNRNVTARYLIDLDCYFSDSTFVKRATPFDRLRDVETGRSTWKPEDVAVDAVFSQLFQLPLPEHKLVYYHSVLTEACKIAPAAIAPSLGRAIRHMYRNSSRIDLELSQRFVDWFSHHLSNFGFTWKWTEWVDDVYLPDLHPQKAFIIGALDKEIRLSFAQRIKGTLPEPYQPLIGPEKEKDVPDFKFSDESTPFSAEGREIAALLRRKAPDEEFQPIIERIHSLAIERSLDPLVTSTDVFVTAVCWVGSKSLSHVLACIERTKDRLLDVGAASEAAKSQIITAVMSYWAAQPGVAISIVEKLLNYSILLPISVIEWALSGGSHVQGQSSGDSLAQPHVFELVFGTVSKVTGRVRQLLTKESEADEDLKERETKAMRDLFKAMEDALVSWASGSKDEMMEEMDGAGQRDALLRRWGERWLRAFRRRSAIEEAFISEATKEQVALDNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D333</accession>
    <name>A0AAD9D333_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDZ83DRAFT_746262</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371913.1">
        <property type="nucleotide sequence ID" value="XM_060513240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D333"/>
    <dbReference type="GeneID" id="85397138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="222"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="393"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1731858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="868" mass="93709" checksum="D79BA0C080506E03" modified="2024-05-29" version="1">METTLPFPFLISVAVPPGLAKLDGLDREQVSILGAPFFEANDQTLDKFHSFLKQHNAEFRGYFDVTGISAKDDVVSLLDAGARMVFVSPENLAQYEEFGSRVGSILTTDDVTTKPASKHAVLVKDFDPTLCNLGSFIEHCKVEKLPNLFIKPVPESNLEHFVDIAKQCNAIPVLPSDGLTASKEESKKLPLSKLIASFWKSDRPDGLIPTVVCDESGTAMGLAYSSAESVGEALRTRAGVYQSRKRGLWVKGATSGDTQELIRIALDCDNDTLKFVVKQTGGFCHLEQHGCFGDLNGIPRLEQTLQSRKKSAPAGSYTARLFSDEKLLRAKIMEEAEELCDAKTPQEVAFEAADLIYFALTKAVSAGVSLADIERNLDAKAFKVKRRTGDAKGKWAEKEGIKTTTAPAPAAAPAPAPAPAAKTEKSERISMRRFDLSNSSAAEIDEVLKRPSQKSPDAILNIVRPIIDEVRNGGDKAVLSYTHKFEKATSLTSPVLKAPFPKEAMQLSPESTKAIDISFENIRKFHAAQKEDKPLKVETMPGVVCSRFSRPIERVGLYVPGGTAVLPSTALMLGVPAMVAGCQKIVFASPPRADGSLTPEIVYVAHKVGAESIVLAGGAQAVAAMAYGTESVTKVDKILGPGNQFVTAAKMYVSNDTNAGVSIDMPAGPSEVLVIADKDSNPAFVASDLLSQAEHGVDSQVILIAIDLNEQQLQAIEDELHNQAMALPRVDIVRGAIAHSVTIQVKTVDEAMRISNDYAPEHLILQINDAEKVTEKVMNAGSVFIGEWTPESVGDYSAGVNHSLPTYGYAKQYSGVNLASFVKHITSSNLTAEGLRNVGESVMQLAKTEALEAHRRAVEIRIDHMNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6L2</accession>
    <name>A0AAD8U6L2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_797419</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000189">
        <property type="protein sequence ID" value="KAK1708908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358426.1">
        <property type="nucleotide sequence ID" value="XM_060515890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6L2"/>
    <dbReference type="GeneID" id="85399788"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="250" mass="28326" checksum="FB11F6386005B4FA" modified="2024-05-29" version="1">MDKRKTYKQDRRYIHPNLSLIENTFSSIVQSLESDRSFARNIAMYGSPLSLIMCALAARLVTSHAVPIDTTINPRSLDEQGREKQPWAAHDVQCHNEADFPGHADINPSMQWEASLSFCASDQGKRIFTTYHDPAENHYPTVFRSRYRWKDNWKINYDFYVQWVAGCRTAFGAQRVDDPLLSKDGKPSCASIMNENFKKCNNGGVGGATQVGCLLYTFNGGKGNNLLTVAELEQRKIYDEKYSITRGPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8G2</accession>
    <name>A0AAD8U8G2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BAR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_797730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000218">
        <property type="protein sequence ID" value="KAK1706958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357958.1">
        <property type="nucleotide sequence ID" value="XM_060515905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8G2"/>
    <dbReference type="GeneID" id="85399803"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07591">
        <property type="entry name" value="BAR_Rvs161p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000014">
        <property type="entry name" value="Protein hob3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037429">
        <property type="entry name" value="Rvs161/Hob3_BAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01251">
        <property type="entry name" value="AMPHIPHYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="4">
        <location>
            <begin position="17"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1706958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="261" mass="29998" checksum="5BDBDB17AA4F6222" modified="2024-05-29" version="1">MSWAGFKKNVNRATTQVMMKTGHVEKTNDRDYEVEERRFRTMETASLRLQKEAKGYLDSLRAMTASQMRIAETIDAFYGDSGAKDGVSRSYKQAVEDLDAETIKALDGPYQQTVLEPISRFCAYFPDVNECIKKRGHKLLDYDALRAKVKKLVEKPDKDVTKLPRAEKEMEMAKAAYEQLNEQLSSELPQLIDLRVPYLDPTFEALVKIQLRFCAEAYSRMAQVQQYLDADTREQYAQGQLDQRVEQVLQEIRELSISGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9X8</accession>
    <name>A0AAD8U9X8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_796097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360166.1">
        <property type="nucleotide sequence ID" value="XM_060515859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9X8"/>
    <dbReference type="GeneID" id="85399757"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042282380" evidence="1">
        <location>
            <begin position="32"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="38513" checksum="5ABC6EF015689DA9" modified="2024-05-29" version="1">MSSTSHSFGASGLRLLLSWAVLQAALVGASPAPVARPDTLPYPDDEPLAKRVVGQFPSFPNDYNGRVQKGVYLRTLMPLSDAEATRHNRGVSVASPWQNQAAVEQWGWTREINWAPFNTNGGDEFSDGDDFDQFETSPGFGNLMDDVFADPSHPVDPMENGLSTFLHANDFTLRDGSWGEPSQASYQNVFNPRSGAIIFDRDFSPRYQIAESGAGDVPELEQLSDLAYFQWLDACAAKRIRPNNINLIFQSHITYVPSFNLIAQALYDAGHRRVPGWGQRVTFSMDSRPGLAILGSTHGAAPALFLIQHKATFGRKVITEVTVWGGASGFSFRANPEVETLNLRFTVRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAB4</accession>
    <name>A0AAD8UAB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell surface protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_189392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357921.1">
        <property type="nucleotide sequence ID" value="XM_060501584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAB4"/>
    <dbReference type="GeneID" id="85385483"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606:SF1">
        <property type="entry name" value="CELL SURFACE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39606">
        <property type="entry name" value="SURFACE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="61453" checksum="07C058248D7AF1D8" modified="2024-05-29" version="1">MGLGAKIKNALHSDDHPQKTTYEGDQPPGAFPSDSTTTGTSKHTTGGYTGGTTGTTGSHVPGTTGTSTHHTSNTTTGYNDPDGVHGPHAGRVANKADPRVDSDRDHRDAPTSGLTGNTYGTTHGTTTGHTGGLTGSNTAGYSNTTTGYNDPDGVHGPHGGRAANKLDPRVDSDRDHRGAPTTGLTGSNTYDNTTGTGHAGGLHNNPHGTTGSVGGVAGNTTTGYNDPDGVHGPHSGRAANKLDPRVDSDRDHRGAPGAGLTGTHRPHDSGVEVGHGVGHNKPYKGEYLANAERTNAQDPYWGDVGRDGSALNTDLPLRPNESAVGHGGPQAVGGGHYNPAASTHHDPASSVDRSMEGRDFTHPHSSGAGVGGAGSDPYSGVHSAAHNPQAALSGGNVNDPYDTRMRDRDMGRERTGHGAAGAGIGAGVGAGAAVAAGQAAHRHRRDDLHESGLGGNNTVGSVNSSVGHNTHGTHSGVTGTHGGVTGTHAGGVHDHHRSSLTGNEPGVPKTSMLDPYNESPTGTHGTHGTTHSNVASTGLGGNTGSSGLNQGTHSSHVPGTTGLGPQGMGPDHYGPGHDGAKVFHTCTKCGEDNDISRYFKKDAVYRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAH1</accession>
    <name>A0AAD8UAH1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pantothenate transporter liz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_758342</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357904.1">
        <property type="nucleotide sequence ID" value="XM_060515021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAH1"/>
    <dbReference type="GeneID" id="85398919"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:001719">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF43">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="71"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1706776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="57089" checksum="2FBA2C358210C653" modified="2024-05-29" version="1">MSNIKSVAPVAVSDAISDLDKNVKDTTPVNAAEAIPEQSPSRWRKIVGLVWDSVDGDPEYRKYVQRLDTFFFPTVCFGYFIKYLDQTNYSNAFISGMQTDLGLYGNERNWLNTWFSLGIMVGSVPAQMSQLSFIRPSVLIPSCEVIWSLLVIGMGFAKNIETMYALRFFIGLFEACAFPGYIAMLGGWYGPKELTKRLAILLQVESIASMFSGYLQAGLYTSMDGRHGIAGWRWLFIMDAIISLPIAFWGFFGLPDLPHNTKAFYWSAEHVKYGINRIEKFGQKAQQKLTWKEAKRIYLGWEIWVFVVPYTMVAACHTATSYFNLWLKSAGYSVVDANIYPTGGSALNIVATVIWGIIADRTGQNYTMIVIVQALMILSNVLLSVWYIPKGALMFAYYLSYAGSAATPVLISWANRLNAGDPSLRQLLVATANVVSYAWVLWVPLVLFPTYDAPKYKYGYQILILFGGLAIISVTLMWYMYRRRDQKRAQEENQGTEAGLERPDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAK2</accession>
    <name>A0AAD8UAK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_593490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000218">
        <property type="protein sequence ID" value="KAK1706949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357949.1">
        <property type="nucleotide sequence ID" value="XM_060506631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAK2"/>
    <dbReference type="GeneID" id="85390530"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF81">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="34"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="162" mass="18703" checksum="D226179DD038F947" modified="2024-05-29" version="1" fragment="single">EFRLAVLYAAGDKGKSYPIHVDLELHKDTHFPDYDAVSYTWGDENSDAERCQPVYVGDHWDIIFQTKNCCDMLRYLRSSRGMKLLWVDAICIDQNNTDERATQVAKMNQIYSRCSQVWAWMSSDLVSDNLEGLPERRWLHELGTAHDYAVTSSQSQPIPNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAN2</accession>
    <name>A0AAD8UAN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_765178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000155">
        <property type="protein sequence ID" value="KAK1711879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359203.1">
        <property type="nucleotide sequence ID" value="XM_060515246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAN2"/>
    <dbReference type="GeneID" id="85399144"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32302" checksum="9B4E7161994156E6" modified="2024-05-29" version="1">MLFGGWKESCPQIANGQVEATKSEASKEEVSKDEVSKGKAGEGEGPASKDEAGEGKPGEVEVSKDKASEGESAESKKANDWIIELPEDGLEEMILMLEIIHGHFDRVPFSLSVRRLHDLLVLCNKYDVLSLLRPWSWHWLSAMRSTLDEPYVLWVAWEMGDVLLFRDMVVRIAEGVPISALNNPNVMGVQYGKQRMHWTPQSGQINEFPMVPLDCLQNTSADDLSDLISLTRLMLIEAAVKPYRTILSQMKSKTHSSNQNAIKNNCVKNCIPSGVGSLVLAGTPGYLSTSQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBF0</accession>
    <name>A0AAD8UBF0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_756789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359668.1">
        <property type="nucleotide sequence ID" value="XM_060514796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBF0"/>
    <dbReference type="GeneID" id="85398694"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF23">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="722"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="753"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="840" mass="93757" checksum="6A9601189D4FB53B" modified="2024-05-29" version="1">MDLTTPAPASGSQPPDGSDGDIPSCQGCRRRKLRCSRDQPICSHCKRLDSPCVYDLKKNKPGIKPGAVESLNRRVEVLENALLQKSSEGSYPTSNGNGNTESHSAPAESQNVVGILSLLARELHKLNSKTKAGSQAGTPEGAAEHAVFSPTTSSSSRRNTIDGIEIVSHPHNQPRKRRRVDSCGNPNIDLAFPLEDLENITTSLPTPELLEDIINIHFNIIQPWIPILHETQFRRRVHDPEQLPRLVVVLHAMVVAALRFVDNSEIRLSALEVERRTSRSRNIVILNAMDHLSVENLQALVILAFNDIGNGDASKAWSIVGSLTRTVEYLQMSIEADHQDKEPLLKPLPSIPPPQNWTEEEERRRVFWNIFNLDRFCSVTTGWNTSLTSDDVYRRLPADGGLWHKEESVITPFFGIWDRSAAKMGNSIAFLPAHYPSPEQTADAPPQTPITAHPRKGPNTVDMTTVGAFAYCIEATESLSRVTTYFLQQKINFLDRQEVSSWLTRFKELDLRLVHWKMFLPQKWKDSNISRQPALINMDPNLTLAHITHNTSMILLHQRIAYPEPRWSNIVKLPSFCSAETCQEAAVETTTITEKYLKYTPENSPATSQFAFCVFISARVLLVHWRYYDAELAPEFWTLVESMEEMAKRWVGPILKEKHAQCLAGKYAAQLRDLHRKCQADPQFTVDVLGYSSGVSGQGCSPAAQTPAFSHQQGNALFAQSSNRMAPPVSSPLAPNQTTGLSQPRPPPIFSNQQPQGQMRQGSMMGPMGSPMPMTGFTPRDSDAPDELSAISHMLMDQRFMEMDRIISFDDMMFTAQTANNGNASMPVNGWGPVDNTQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCA3</accession>
    <name>A0AAD8UCA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_461076</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361542.1">
        <property type="nucleotide sequence ID" value="XM_060503234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCA3"/>
    <dbReference type="GeneID" id="85387133"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="653"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="688"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="720"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="768"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="799"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1719458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="896" mass="101767" checksum="A4ABD3AA959961A7" modified="2024-05-29" version="1">MSDIREERAPVHQGGVVSNEKVSTEKTAPIVDAHPDGADYNEHVEHDFNVTEDDLLEAKELASQMSLEEVREMMFNVHKIHEKDPNFPLAIIEKIEDFLHNDDVFENPEKHETLIQEMKLEAALITGNSPYAEVRAVVDNHDDPTMPSSTLRAWVIGLVFSALLAFVNQLFSVRYPSITILANVAQLLAYPLGKLWEKSLPDVGFTVAGHRYSLNPGPFNRKEHMLITIMANVAYNIPYTNYIIWTQWLPKFFNQSYAANFGYQLLISLSTNFIGYGLAGLCRRFLVYPSYCVWPASLVTIALNSAFHTDKNSTVDGPFNSIWRWSRQKFFYITFAAMFVWFWFPNYLFTALSTFSWMTWIAPKNRNLATITGFNSGLGLNPFPTFDWNILLYDNTDPLMVPFFSTFNKFLGTFISMFVVLAVWYTNTYNTGYLPINSNKVYDHFGALYNVSRAVNEHGLFDKEAYEAYSPPFLGAANVMIYMFFFAIYTATITYAALYHRHEIALGFKALIGSFRKNSDIEKDQVLDVHSRLMKAYPEVPEWHYLTVLVIAIALGCAGIAGWPTYTTVGVVFYGIILCMIFVVPVGIIKAMTGIEVTLNVLAEFIGGSWVEGNALAMNYFKSFGYVTCAHAVWFSNDLKLAHYVKIPPRHTFWAQIVATFVSTLVCLAVLKFQMFSIPGICTEDAKFKMTCPGINTFFTASVLWGTVGPKKIWGAGGQYTATLLGFPLGVAIVLFFWSLNKFFPKWKWVRQIHPVAIMYGGLVWAPYNMSFVWPSVPIAYFSWVYLKSRFLGLWSKYNFVLSAAFSCGIAISSIIMFFGLQWQDIEVDWWGNSVVRFFPVPNLILKDPTNIPLLTGQPGLRRQGLPSAYSCRGRVLRSPHWRLPLDVEVSFVLHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCI8</accession>
    <name>A0AAD8UCI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SIS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_654576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361677.1">
        <property type="nucleotide sequence ID" value="XM_060510728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCI8"/>
    <dbReference type="GeneID" id="85394627"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF/GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418:SF2">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF_GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="109"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="419" mass="44925" checksum="FF3F132598B22B13" modified="2024-05-29" version="1">MGDQRHHMEHRPVQNSAVFVLGANHCDSMPPPSPPSPPVSPPEDDFLEELEELSLGSPDDLPENDDSSVKVQDRLHAATHVLKTEAAALRSVANLYETDPVARDGFNRTVAAITRHKGEKGKLIITGVGKSGHIANKLVATFNSLSLTSVFLNPIDALHGDLGIIQKHDILLFITFSGKTSELFSLLPHLDKPSSLVILTGHTRPDTCELIKLRPDTILLPAPVHESETSSFGVSAPTTSTTVALAVGDALAIAAAQELHPSVAQVFSKNHPGGAIGAAFRKPQTILDLAIPWVDIDDSEHLCVDSSVGADLFRAAYDSPSGWVRVGDAVASPSRIRKLATVDFTRSLRDIPHLLVSRAEMLSISSGTTIRRAVDFLRSMQGAADDGEYVCNSDSLLAVLDHGDMVGVLEAGKLLEWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCP7</accession>
    <name>A0AAD8UCP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pepsinogen c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_755983</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360602.1">
        <property type="nucleotide sequence ID" value="XM_060514688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCP7"/>
    <dbReference type="GeneID" id="85398586"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF68">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042084385" evidence="4">
        <location>
            <begin position="20"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="33"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="390" mass="41775" checksum="BC94FBE675E2571C" modified="2024-05-29" version="1">MSPVTRFFSAAAVASAASAAVLDLGIIVDNGYKVVEFGIGTPAKTFRLLFDTGSSSSWATDSQCLAKGNCNNGSGYDRTGYSINASTSGHYTGESAVIPYLGGDVAGPTVAEKWTVGNFTWDQSFIAANESNWAALAADGFMGLGFSSIIDGGANTVVETLMAENRLDAAKFGIYYGTEAKNTSGVPGDGVLTIGGSREDEYVEGDLVTIPITRVDGTYDVWRSTILKVNGTRTTSNGSVIETQTDFDQARVVFDTGAGSITLPTKQNLAVYESIGMNYTKILKGEHIPLCSEFNSSWSFKFTFGDYRYPQTIEIPGDQLARPGFAYRDDACWPPFEDGAQSGFVLIGTPFLKNFYTVWDYGSAANETVIGKFDPTLSFGYLKNKTTPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCU3</accession>
    <name>A0AAD8UCU3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359429.1">
        <property type="nucleotide sequence ID" value="XM_060510884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCU3"/>
    <dbReference type="GeneID" id="85394783"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="27624" checksum="3F43692FDBB0FFCF" modified="2024-05-29" version="1">MVNLVGVPRSKAADNLEHSKRKVRGGGRQDHDVGFGVRCDETSRRVLEGAAGLKMELSPVHFPECPPRDPKGHQGWPGLGCAPYLRRGHARAFPAQTVRSTEDPEIAPLRPSLFGLFFTTYCPSTADRSLPPPFFNLKGTKDTPYSKGDSNTAVCRASKTQCADAYCVSIHTAFLQDIIPSAIRIQSHVCKVRESSDCQSRIPPLSRSSASSLQSRVALHVPILECSELCPSFIQLSNLPTWCGASIALVLIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCY9</accession>
    <name>A0AAD8UCY9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_638184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000144">
        <property type="protein sequence ID" value="KAK1712888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359504.1">
        <property type="nucleotide sequence ID" value="XM_060509351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCY9"/>
    <dbReference type="GeneID" id="85393250"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="526"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1712888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="933" mass="104198" checksum="448263DCA60044D9" modified="2024-05-29" version="1">MPLSHRLGQALAEARSKARSVYHLLRDRGVNDEARVAVRILLGTLHSLWLLFEDFSEQGTSPACPDHTIFDDLSDLLDNPSLEWSASSSTPSEPPSLSAFTSGIYRIQCQLDFLVRCDSWAALLVRLSTDSHRKDVLSQHLDHTGEFIPKPTEIDSDRCIAILLNAEFDKQLTECFIHRQYVAERDIKCPEYGAAAKLLPDLARQRYTDYKTPLHVLFHSRKSSHFLQWLMEYARQEWPEHFNLSSGALSMTPLNLLMSRLEDDLVTPFHVAASLGLPRLCEQLISWGVDVNKPSSMGTPLYCALLGPTALLGRSADPSQLVSDCKPTDSQEETIRVLLDSGASCTVETAGPCQDEKFSLATLAFLICQAIRAPKILLQLLKSGISLDLRFVQLFHGKDSLLQYWPSPLKPPTRSFLEGMLPAILDRAIPEYDSYNDISLLATGIYEILDHFDLARPSSIARSRPLDVSDTLYVELVREAVQDGETAVVRRLILDPRWNPNALMAPQRALSIASSEDEFVMGEPRDETTILHYAAETDEIALLAAILTSGEDVNVHVRNHKDQTPLMLSESPEVFRLLLDHGARTTDTDESGRNVWHFAAANSDIELLNCLQEYDKHKDHNLRAVMNDGQTPIAEAVLYPFSSMRKGQKITPAALKGAIHMLKICRPDLAYLKSSEPLVLLAVECGSADLLRSLVDFGADPFEVDGVFRNALHYLNVSATKPLIDILLNLDFETVLNAQGISPAETIFQVFNDRALFGPTSATHPASFCTLDAGVYSRLLDYKNILASRDDTNTGLWERFSRNVFATDAPRWPAGLTESAQPSLQTAIECLIKKGALTKYEEERGRCGIIPIFSRWTEISGTQKRLPKWLESILLPILEATTKIDEVRESPGVVEFITQATELENHEISQQYLDTGDHEMAQHYLDLGDMVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCZ4</accession>
    <name>A0AAD8UCZ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_757299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359134.1">
        <property type="nucleotide sequence ID" value="XM_060514875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCZ4"/>
    <dbReference type="GeneID" id="85398773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042258238" evidence="1">
        <location>
            <begin position="19"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="75" mass="7806" checksum="DBF63D7E6D024386" modified="2024-05-29" version="1" fragment="single">MRFSTVAAALQAVAFVQAAALPAMPAGELIELVKDDTISLPGDATVDLVARKEVNEVHAIESIAEQTNSADKSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDI1</accession>
    <name>A0AAD8UDI1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar H+/Ca2+ exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_437179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362202.1">
        <property type="nucleotide sequence ID" value="XM_060503081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDI1"/>
    <dbReference type="GeneID" id="85386980"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="58873" checksum="E74CCBF6D7997F75" modified="2024-05-29" version="1">MDVSNLENIVRSYGIAIDRHTLQAALDDPEHGTAFTEWARLHLGPENLLSRDELALYTALDRSGQIDKLVESQDLAAVQAVSEREIQTAIEELNRATAAIVKQTETLKQQQDALSKLIKTHSRVEEARSDLVFQRNQKHDTERRKMMTTVEELSQSLEYKASDFEQQSKVSGNGLQQTLDSLLHSDDKLLSSLRKLGLELETEDPEDRENVEKLREICMRLIKYTVETVRAKLDRLYLEALNSAHQNGVTSHPSDDVKTSQEELESLYAEILPVAQMSVEQQHLEPALKSLSSKNGQSLRRSAAAVIYIDECLDYLLDHMDRLSTRIEGYQSHQTATSSLLTTARAELSTPVATPKKKTPTQDLVSPVRRRNNTNPGRSPTRDGVTRRRRSSAYDEPPLEALLRSLAIAFPEDATDSAGQTAVLAATLAERQTKARDVARNAQETLESAAATQLADSKLAIQLLRDSLLAESPFGDVRLVDEGIEASIAVLGQEVEKVKERVEKIDAGKARLRSERKREILERWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE06</accession>
    <name>A0AAD8UE06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_637266</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359838.1">
        <property type="nucleotide sequence ID" value="XM_060509296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE06"/>
    <dbReference type="GeneID" id="85393195"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="52"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="116"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1713785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="183" mass="19233" checksum="ADFA8A359B718326" modified="2024-05-29" version="1">MALSCRFAAQSCARQLRATGSMRASTSLFQTRTPATARRYNSTEAAAPTNPKIAAIVDQISTLTLLETADLVSSLKSKLNIPDLPVGGFAAAPAAAPAAVEEAEEAAPAAAEKSVFNIKLQAFEAGSKPKVIKEIKNLLGLSLVDSKKFVESAPKLMKENVAKDEAEKIIAAMKELGATVTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEF7</accession>
    <name>A0AAD8UEF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_723171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360063.1">
        <property type="nucleotide sequence ID" value="XM_060512529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEF7"/>
    <dbReference type="GeneID" id="85396427"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF160">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="54"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1714920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="57860" checksum="E9F4C16BE5B6D263" modified="2024-05-29" version="1">MSRASSRSSDRPASADLSGSIYLITSDGKTLKLPMPSNSPYDPLNWSLPKRLVAMGVLILYSIVSMLETQAASLMYKSLAVEFNGQFPLNILVSTPSTIFLGLGAFLWIPLSVAIGRRPVFLLASCFMTIATALAANASGFYQLLGALSLQGFSAGLSLSASILIVIDLTFIDERPNALGMFWSIGCGGGLVSLRIVPALAAPGWRSFYTAWLVPCLAVFVCAFFFLPETYFVRPAVAFDGHILVQGGSEKVKMYDDWEELPGGKTSEVIQSEAAPETVWQGMVRRWGVRKSGAGFREMWTCYVQTMLCACNPLVFWVAILNALNFGAMIFIGETYAVVMSQPPYNLPERVISMVNPVSAIGSLLAWPVSTILTSRVARRLTLRNGGIRDAEHYLIAFLPAVLAGAGSIFLYGFTVHYKWSFIWIFVSYLINAFSAAAYGIASTLWVTEAFPRWAAPAMVIVGGAGYMLSFATSYAVTPWLRSQGYLGANFELGAILLVVGGVAVPLAFWGKSLRQYIDGRWGVSEAGALRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF41</accession>
    <name>A0AAD8UF41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_54194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360366.1">
        <property type="nucleotide sequence ID" value="XM_060503406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF41"/>
    <dbReference type="GeneID" id="85387305"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041932868" evidence="2">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="9256" checksum="B305BF08792E7257" modified="2024-05-29" version="1">MTDLATVLASLVLVVTEGTVEGSKLAKLVALELVLSFGNGRGLAEESCQHSLPIVIEKVGGGLTVSMTLWMSFLALLTFSSVSAMMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFB3</accession>
    <name>A0AAD8UFB3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_634985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360528.1">
        <property type="nucleotide sequence ID" value="XM_060509139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFB3"/>
    <dbReference type="GeneID" id="85393038"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="337" mass="35944" checksum="2857CAE9EEE59E26" modified="2024-05-29" version="1">MAKLSATWIRIASSNRLRRSSQAVSAIGNQAFVFGGELLPREPVDNQLDVVELLSEKGSASAKTISTDTETPSPRVGAPSTVLKDAFYLFSGRGGIAMEPVEESGSVWRYTPTQARWDLLKPTDATAPHPAGRSYHCTASDGNTTIYIHAGCPEKGRLADLWSFNIESKTWKELAAAPPPARGGASIAFSGGKLYRINGFDGTSEQGGSLDVYDPASAAWSTITYNPDGVEGPEARSVSALVAVEVSRKPHLVTLFGERDPSSLGHAGAGKMLSDVWAFDIEAGKWEKVLFEGGAPPPRGWFDADVVVDGGKQAVVVHGGLAEDNSRLGDIWRLDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC9</accession>
    <name>A0AAD8UFC9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_721777</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361922.1">
        <property type="nucleotide sequence ID" value="XM_060512411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC9"/>
    <dbReference type="GeneID" id="85396309"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000012">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1720411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="41710" checksum="07E2A48D70141CDB" modified="2024-05-29" version="1">MASDLAEHPLRACQLSYNLTSSPQPVPSEATILSSDQSICTDHMVVASWKYGIGWSKPELKPYGPLNLLPTASCLHYATECFEGLKAYRGHDGKLRVFRIEHNVARLRSSAARISLPTFEPGEVKKLVLGLLAVDAGRWLPEEQAGGFLYVRPTIIGTSPQLGVQAPKEAMLFIVLAYMPRLDVPPGGMRLYSSPKDAVRAWVGGFGYAKIGANYGPSVLVLQEAASRGYHQVLWLYGEDGECTEAGGCNFFVVWVRKDGKTELITAPLDDKTILDGVTRRSCLELARERLGEEIEVSERKFTVTEIMEAAAEGRLLESFAAGTAYFIAAVSHIHHRGHDISVPMGDAGKGAKITTTLKEWLTEIMYGDTEHPWATIVSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFD9</accession>
    <name>A0AAD8UFD9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DSHCT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_755844</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360780.1">
        <property type="nucleotide sequence ID" value="XM_060514673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFD9"/>
    <dbReference type="GeneID" id="85398571"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000003">
        <property type="entry name" value="ATP dependent RNA helicase (Dob1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="183"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="453"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1115" mass="126069" checksum="59BEAD4D541B9923" modified="2024-05-29" version="1">MDELFDVFDAQPDAQNESHSEPEPETEVAEPPQKSRKKDKKSKKRKADGGMKNGVADKPEDDDMPDADETSKDGQDADEAEDAAASSDEQQEPHKDKRRKKEDEAQPVLTDTFQTAQSREVAGAAVFTPAQDESLVLSHNIQHQVALPPDLDYEYIPLSEHKPPAEPARQYSFKLDPFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCLKRNQRVIYTSPIKALSNQKYRDFEALFGDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEIMREVAWVVFDEIHYMRDKTRGVVWEETIILLPDKVRYVFLSATIPNAFQFAEWIAKIHHQACHVVYTDFRPTPLQNYFFPAGGNGIFLVVDEKGVFREGNFQKTMSLIEAGKGQDPNNANASWKGKGAKKQTQKGGQASDMKSDISKIIRMIMQKSFHPVIVFNFSKKEVENLALQISHFQFNNDSEQAMVKTVFNNAIQSLSEADRELPQIQNLLPLLQKGIGVHHSGLLPILKETIEILFQESLIKVLVATETFSIGLNMPAKTVVFTQTNKWDGVQRRPLTPSEYIQMSGRAGRRGLDTRGIVIMMIDDKMEPDTARGMVVGEQDRLNSAFYLGYNMILNLLRIEAISPEFMLERCFHQFQTGASVPALERDLVALQQERDSMSIADEATVKDYYNLRNQLEQYTSDMRAVIQHPEHCTDFMQPGRLVRIHDPKKTNNTIGGTDFGWGVVANLIRRDRNRKQGEPEYPPQESCLIDVMMVVDQKSAPVAEGSRHLTSDLPKGLVPYPNPEQPDNGARFEIIPCLLTCVKSISQIRVFMPKDCKSQSALNEVGNSLREVHRRFPDGLPILDPVENMGINDDSFKALMRKIEMLEARLLTNPLHGSPLLPELYLQYRSKEKLGEQIKSKKKEIARLHSIAQMDELKARKRVLRRLGFLNESEVVELKARVACEISSTEGHELVLAELLFDRFFNELSPELIAATLSCFVLDEKLETAALREELAKPYREVQAKAKQVAKVSRESKLELNEEEYLAGFKWQLMETVYSWAQGKPFADICKMTNAYEGSLIRLFRRLEELLRQMGQGAKVMGSDELTQKFEDSLAKIRRDIVAAQSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGA1</accession>
    <name>A0AAD8UGA1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GAS2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_586524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360981.1">
        <property type="nucleotide sequence ID" value="XM_060505960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGA1"/>
    <dbReference type="GeneID" id="85389859"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAR" evidence="5">
        <location>
            <begin position="687"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="378"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="643"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="781"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="672"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="782"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="878"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1717494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="926" mass="101814" checksum="034D09A4BC4152F8" modified="2024-05-29" version="1">MTDPPPPITPGPGHQLRPARRQYRHSDEHSPTRARTNADLLSRLTPLTAVEMLQTPNTELKQCLDNSTVNEQEFAMRAAVASRKIYEWLEELSDWPWPSTSGSAGFEMPEAKRTKLDEDADESVYLGSLPAESVAQYEQRVDGISHDMDELHIEEIKTHVMHTHIIPLSRPGTPLSPTRPMGGGALSYNRMDDLTALLTAIIVQALPNLSKLCRLLKVWHIRLSVLRRIPDLLSGIAEAEYALESAWNVLSSPAGTPSAEEGAQDGLSQLKHAVTVVKSVLETQITKSGRSLDFMLDSLEGLQDTLPDAWLDRMEAVERNYADWVTSGEQRIRQGDWASVRQQKALPPVIREEIEAEPTKSSGLPVVDEDVRTVTLPVPITINPPEEDSQPAPDVEATPEQSDGSEDDTIELSPSQLQAQKKTQPVAGLDGSNEATKPKRTPLGEVQNEENTKRKVSGKESVVSKLRAVFESNARSSSDDADEIMPDDEEMQLPPLIRPDRRGSDASDSSTIIHGHTSLLADASSDMPEVSASPPLPRQKRAETLSRKSAADRFMSMSPPSSPPSRPSYREESVSPMMRPQDEGLLPALPLESSFNEEDFDHSFISMGTPRETGNKEDDHLRKQISDILESIPANIKLARATPKVDLNPPPPDLPTMPAKRLKKPSRETMRRSVSAMSTTSRTSSRATTPWLTLAPAYAKNPRPRRPQSGQDVRVYHLSRSTGEAPIKLLIRCVGEHGERVMVRVGGGWADLGEYLKEYASHHGRRSAGPVETAEIKVQDLPRANSRAANSSPPSRPASALEMSPMTPLNVRKSRKSFGAGDSSVPRLLPNTPAVPPIPDKFTPTPSSEDSNRSRSSSHISWEEDESSFLGLAGPTGRKVEMSEENRAWVESVKEKVRAASGETRKISEFGDMGKVGGTKRVFRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGD6</accession>
    <name>A0AAD8UGD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_743614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361098.1">
        <property type="nucleotide sequence ID" value="XM_060513142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGD6"/>
    <dbReference type="GeneID" id="85397040"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000556">
        <property type="entry name" value="MFS transporter, putative (AFU_orthologue AFUA_1G17530)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF55">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="64"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="524" mass="57711" checksum="8B5060D7E99609B7" modified="2024-05-29" version="1">MEMTTDTTEKSRHTALDDGFFTASGADDKNAPSQAAKLEAIGEEGLAIDPVIEKRVLRKIDLFLMPAMMIGYGLVYYDKAILGSAALFGMTGDLHLSVVDTSFTPPKTDTTRLSWATSIFYFGQLIGSYPMTYLLQCFNTRWTLGPVVMIWAVICAATAGVTTWQGLLVQRFFLGFTESVIPTAFMTIVSGYYTQREQALRQSWWFSGTGWFTIIGSALNYGFSQIQGGALTPWQYIYVLAGGLTFLFGIWCFFLPNSPLIAWFLTAEERVVAVERLRQGQTGVKNQTIKTGQIKEALMDAKVWLVALTMASGYTVNGAVSGFGPLIVSTFGYSALDSILFQFPLGAICAIGIPLAGWVCSKYRNIRIPVLIGCTLPVVAGFIIIWKSDWSHRSVAPVVGYSLIGFFGPVVSLTVTLGASNVAGETKKSFMASAVFVAYCVGNIVGPQLVKSETKAQHYPELWTGLIICHLATALLFLSSSALYVILYRENKRRDALGLDESERHRLTFKDLTDKENEHFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHJ5</accession>
    <name>A0AAD8UHJ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_457956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361641.1">
        <property type="nucleotide sequence ID" value="XM_060503209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHJ5"/>
    <dbReference type="GeneID" id="85387108"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="143" mass="16177" checksum="17604D892983C824" modified="2024-05-29" version="1">MEPYFRLFSAEESASGLEPSWHPISQESLMAPPVTTVTVRVEALDSWEKLWVELNRYCVANTSTDPNRPRAKDAQLEVTTAGSFLTTHEYISVVHPWLMGMRERILDALRKLERQAGEVLWTPEAILAVHLFDGPIRIGTEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHL8</accession>
    <name>A0AAD8UHL8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Beta-xylosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_707308</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360875.1">
        <property type="nucleotide sequence ID" value="XM_060511544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHL8"/>
    <dbReference type="GeneID" id="85395442"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18617">
        <property type="entry name" value="GH43_XynB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041542">
        <property type="entry name" value="GH43_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051795">
        <property type="entry name" value="Glycosyl_Hydrlase_43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812">
        <property type="entry name" value="BETA-XYLOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42812:SF16">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17851">
        <property type="entry name" value="GH43_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042144983" evidence="7">
        <location>
            <begin position="18"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-xylosidase C-terminal Concanavalin A-like" evidence="8">
        <location>
            <begin position="337"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1717388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="571" mass="63059" checksum="F3064DAE392657A4" modified="2024-05-29" version="1">MKLLARATLLLAAFVSAIKNPILPGWNPDPAILRVQDTYYMAVSSFTYYPGIPIYKSTDLAKWDLVSHALQDPSVLALYGVSAGEGVWAPSFSHHNGLFYITSMTRWGSDPDSRPWPRIWYISSADLVTWSTLTWAEPYGIDPDLFHDSATGKTYLNLMGPNNNYDRLWGITQCEIDLATGKCIGRYRNIWNGTLPQLPSSRPEGPKMFKRGEWYYLLLAEGGTSTGHRATIGRSNSPQGPWESSPTNPLIYNGADPKLTVQSTGHATFTDTPDGEWYASLLARRNVKGASPLGREAFLVKVDWEDGWPTMNGGKPLLLSEIVEGPNQEYPKAKWVDDFTGLELGISWYQQRTPYTENFRLKGATTGAFGKRVVANDSGIVFNPNVFTLGDRDTAAAVLRKQTSLNMTFSARLSSTSAGLGPRQSVGIASYLSEVNHQDIGVRGCWNTTGLCLYVDLLPTSTGPTTRPNSTEYPLGELTIPADLTLHIRASPLEYSLGYSRGNATSSTWLKTFSSKQMGSNPGYPNFEGSMFALFASGNGEPWPYDAPEVGFNRVEEVYFDEGLPDYDNWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHP3</accession>
    <name>A0AAD8UHP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Frequency clock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_27723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360920.1">
        <property type="nucleotide sequence ID" value="XM_060502104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHP3"/>
    <dbReference type="GeneID" id="85386003"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018554">
        <property type="entry name" value="FRQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09421">
        <property type="entry name" value="FRQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="958"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1717433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="983" mass="105952" checksum="33C94B2E42388DED" modified="2024-05-29" version="1">MTDAKPSHEGGRPPTSSNGHPLPRRSSPEHSITLRNHRLAHEATEKAALRRALAAASPGSSSSPNRQSSGESHNTGPSDPEKWFDQNNENPATTYAGAMDVDPPFFQKESDSSNDDAKPSAYPTHLRPPMDGIMNRANKPSATHSSSADDYRSVIDDLTVEIKRLRDELKRYKQKGPELMKRDKLFEIKVHGLPKRKKRELESTLREFASGLESSTPSAEASSSRQKSRHNVHLHSGFGYASKHASSSSGSHSRPVDSAYASMSTGANSSGTHLARPSTSSRTKSSEQKVENYLKDIPEGLYPRHMVLTEKDRKKLIVRRLEQIFTGRISGRNLARPQPKSAANIASYAPIMVEPTTGNTTTHHGPSNVPAGYFEPSREAPILASDGKKNIPKDVESSNSNGDQRDSSGNWTTAADVSSTSPQDPPPPEQRPTRPLDLDPDRMQNPSANMDYIRHLGLAPPHLTALMTDGDVSPDADGWVYLNLLCSMAQLHMLNVAPDYIRSAVSEKSTKFQLSHDGRKIRWRGGTEGTKFSSDSSGNTSQLSRSDESDETQPDNQGKKRKQRSGKTGYCSTPYGKNSSDQSKPEYPIPSADIFHYKPLFVHQSSSAEQTSLDDVGSSYGAVEDSNNGESRWDGSGSSRRKRRRLDGAIIYYSGAPFCTDLSGDPGDASPASYMTSSGQDQQLSSSAGFLRPDLPRRTESGSALPYRPLLEGRKARSVAVTTENGSDDSDSGFEADFPWSNNHQDAVGSKLDACGLGGVIPDDHFVVVATTKRPKVDVKQETTMNLQSEDFSKLISRITSPLGSSGSQAKSAKFESRKTTPINIEYTSRSVRKLNPTPLPPPGLYFAFDSDSSDTSDDDDDESDLDNNSKVGGGVQAHAPTFDRQCPDDAQVSSGEEGDSEPDNGDEVAGVAEDEESGAEFKIPLPPRDLRRASSSSAVAAVGTARGRSNSAELPVAAGSSAATAGGAESGYSSGREESGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHQ0</accession>
    <name>A0AAD8UHQ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GPI inositol-deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_630998</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361803.1">
        <property type="nucleotide sequence ID" value="XM_060508874.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85392773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="374"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="669"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1246"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1601" mass="181260" checksum="D7AD6C16B4FEF9E5" modified="2024-05-29" version="1">MSSRWIMSSSDKYQEEKPETCPETRSPSYSTAIVRPLLNKPHRHSAPTLFRGGWRRRPSSSVTGQAVATGDNSLKGPLGLNILFEPSETRVDFIFVHGLQGGSRKTWSLRPEDASTCWPEQWLPYEPGFKHVRVHSFGYDSDWSQIQHSAIRIRDFAESLLANIAHSQLLKKTRDVPIVFVAHSMGGLIIKQTYLLAKQQSIYQELLPRFHSMYFLGTPHRGSNFAAYLKHYLSLPMSQGAKEYVKELLPGSNTVRDINEDFRHVCKDLALWSFHEAVPTAGFYIVDKESAVMGLQGERVEMIHADHRHVCKFHTTTDTNYRMLVDRFKTTIELVDQDCATRQNTQMKSIARALNVPQSLQNDLLGVSEKCHRGTCQWITQNESFHRWLDFDIDHDDEDVDPLDTSKLNQKPPRFLWLNGAPGSGKSVVSGHVIKYLQSYNLDCSYFFFKNDAKATITQMLLSLAYQMTECNFEARQNFLFMIQNGDEVNTQDHTVIWNTLFLGRLFKIQYPQPHFWVIDALDECGKKSLVSLVQKFSKIEPSVPLRIFLTSRPDSPEAPVEQLLNEERIQRLELHTGQEESMKDIAAYIRSRPRLSRLLDDNDSSEKIVSSILERSRGIFLWASLMVDRLDSLYSLEDMQKALDQVPSEMNGFYGKILEGISNSANADKANCILRWVVCAPVPMKIDELKEAIRLDIGHTLLVSTSGDIFAEICRNLVKTGHNSEINFMHQTVREYLTSWASNLYIDHRAGHADIAAICLKFLNSQAFARHTTRRKNQGSVRQGSSSFAEYASLNFAYHLRHSQSKSSKLFSAFVDFINNKSLIWIEKISRLGKLAPFITSIQNLQRHLVRQLERSPPFDDQIQMVNTWVADLTRLVTIFGPTLIECPESIYAFIPALSPTSSVIHRTFAAASSQKVVSGSHDSWDERLSCVLFPSVVKSVASREQQLAVGLSNGTIRLLSTLTLEHLTTMEHGEAVRQVAFGNITNLLASLSPRKLVLWDARYKRIWQKQIKSTAFSVSFNANDSKVFVTLKGNVKQAVLTFSTSDGEQLDSLSIIEDRSDSDSDDHHESLDRFCPEVVRFSPVLGYAAVTYRSSHLTLFDLNEEDKLERLFRIEKKGSEKLRPPQILDVVFNPAVESGLMAVAYQDGDIIVIYFDEDRWYQVGSVSLHSRVLASSPDGMILAAGDTEGGVSLFNFDSLQLIHRLECLEEIVVGIIFSSNTLRLYDVRGRSCNVWEPSVLVRQNATDDTSSDQDDIPGESHLQSPVTRPFDEAKFVTVLTPMGDDKHVFCGREDGSVSIHDVRDGSKIVEFKRHSASIRVVEWNSKVNLLVSVDASTRCIGMRISPHLKHHNPWYQQDLVFNSRASSSVSQAIIEPNGLAVLFSTQRGEELWQNKTPPEPFSASQLSTETSQWMQHPTDKSLLLLFEQSTVRPFRWDDLSSIAFTSSVSMVLPPALKDTTLTNQWFSRVDFSSIVQAFHLQAENQNTFLLLASSNIHTASKQVPVSCTTSSFLGSVKAIVGVTRSAVIFLTRSGWISSFSLKSFEQAKFYTQHLFIPSFWRTGDLLIRTVSKDSVAIAYRDEVIIIRGFLDFDKKVEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHR1</accession>
    <name>A0AAD8UHR1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_630811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361859.1">
        <property type="nucleotide sequence ID" value="XM_060508851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHR1"/>
    <dbReference type="GeneID" id="85392750"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000042">
        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="33483" checksum="1A2CBEDAB6FB6448" modified="2024-05-29" version="1">MRLFQLQRPLMAAAAGLLRTTAPIQSTTSTAAQLLRADAANALVAGRRYASVKSQGAYKLAPKRTIPKKLGAKRTGDQYVIPGNIIYKQRGSLWWPGENCIMGRDHTIHAMATGYVKYYRDPARHPDRKYIGVVFNKDDVLPYPTHAERKRKLNMSAHTIAKPVETPAISASGIPTQVVRPAPRTAKGAPTQPARILKLRDDYSYREDNWRIGRLVKMNIGGMSRKAKLRQKRYAKERNLSGQRAAQARFAEMEVDEWTIAASKRLSEQKNAAVLAKQKKQKQKAQKVAAKAAKSQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIC8</accession>
    <name>A0AAD8UIC8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_439641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362076.1">
        <property type="nucleotide sequence ID" value="XM_060503098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIC8"/>
    <dbReference type="GeneID" id="85386997"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF19">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042094506" evidence="8">
        <location>
            <begin position="20"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="27"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1721280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="26181" checksum="9542BA2891E7E959" modified="2024-05-29" version="1">MRASAVLAATCAMSVTGAAVPRDAAPAAHPWLAPDVAGGAVRGPCPMLNSLANHGYLARDGKSISMQDLIAGLGSALHFNESLVRTLGTPAFATSTTGNASTFNLDDIAKHNVIEHDGSLSRADFAVTGDAKTFNTTVWAETKGYLESGAVASDNKVGVATMASARSKRIATAKATNPSFNLTTSQVTVSLGESAVILGTLGQSYTAPAAPVEWLKVVFEEERLPFNEGWNTSADVITTAQVLGLSQLIATSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIH9</accession>
    <name>A0AAD8UIH9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_584239</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361924.1">
        <property type="nucleotide sequence ID" value="XM_060505740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIH9"/>
    <dbReference type="GeneID" id="85389639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1720413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="671" mass="74401" checksum="E42601041EAF9869" modified="2024-05-29" version="1" fragment="single">SCHRCHERKVKCSGGRPCQNCQQSDKANECSFPQRNRTVKVPQSLLDELFQEIDRLKRQSTSRPHSDARTAENDEPHDTNTPEGSAVQSLQSPLDLQPESSAESAGNETSPAISIDPWFDSLNVFRSPVLIGEAADAAFATRFRQVITDPSAPEPIHLIRLTYASNESMMSLAHVNTTWPGPSRAKFLLEAAMKYIGRSYHIVEAQAITESWKQNTHDASPEAIALRCRTWALFAIGELYISKSTSVHGFPGMAYFAQASKALGYLDERPEVETVELYLLLSFYSMALNRRYSAYVFAGTAVRVAVVIGLHLNIPESQLPDPMVRRHRKSLFWTAYIIDRLYAANLNHPPAIQDDDIGVDLPCEPSTSSSADSRGDSDYHVADIRLAGLLTSIIRSVYSVRTQAEGTCANLSSRVQGCLKDLQSWFEILPRPLQIGDKSLNEPHDHKVVSLHLRFYQCVILATRPLLLHALRIQVASSRAGSSPATSSIPAEATALSKACIRCAHQSTRLLTRAWIDGIFVTFDCFFTQHLFSSLTILAISSLLDGIGSRHDRDVYEEACRLLDQLKMAGNMVAQEYSRHVEVMESTMLSNLKAHTQSQSDGVADPCDDTLTQEIDQNLADGVVPAAGIPWPEPSLQELLSQPVLDVHFLEAAVRGEHSQGIHWPDVYVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIM7</accession>
    <name>A0AAD8UIM7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_583127</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362459.1">
        <property type="nucleotide sequence ID" value="XM_060505619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIM7"/>
    <dbReference type="GeneID" id="85389518"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF9">
        <property type="entry name" value="SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041966472" evidence="3">
        <location>
            <begin position="23"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="36"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="141"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="63499" checksum="4C6236F45D2795E3" modified="2024-05-29" version="1">MAPIIRALAALAAATLFNQVTATTTELPPCLDEFQPFTYQGCFQEKGTKGENALDFRSSLNQQNMTIETCVDACKGNGYRYAGLTYYGVCYCSATINSPTLDESVCSYKCTGNSSETCGGPSAFSVWQDPTFPSGGATVDDYTSIGCYTDDTNHGRTIAERQDSVDSATMTPSTCLAACASEGYAFAGVEYGGECYCGVVMGNYTTATTMDKCNKPCNGDSTKNCGGSAVMEIYVASKLKSLEPCGYVPPVNSVSSSSTISISTSATIPSISIPPTSSTTSTTSTTVSSQAPPSTTTAPVTTSQPPVTTSKPPTTIATTTAPAVCTTTIVTPATCEYGCGSWCNKNLPDFDDNDSCTKAHNSCKLQVSACLKNAGWPGSASCMDFKAWCSDVSSYCSSSCKGKGSCSKKDCFAKKAPKGYKPGTTSVSTFPCPSKPTTTSTPVTVVPPPPTGVCKQPSSWWFGYGPGNPVGGIEIPIVTCNDIAIDFKAGNQFKLYLQADTKLCKSFGRGSVASVCQDACKEQYNACQNTYAQGCKTWNNRRGRRDDAAVYARAPEFAKRWFFSDNFSVAINKCTVQYTDCLSENRNSYAASKCGSFGTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIQ6</accession>
    <name>A0AAD8UIQ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364048.1">
        <property type="nucleotide sequence ID" value="XM_060514287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIQ6"/>
    <dbReference type="GeneID" id="85398185"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="96"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="337" mass="36658" checksum="FA4FC88F866AAA26" modified="2024-05-29" version="1">MLSIEEILALAEPNAEFIELQSESPIRVGAWNKDTDIQQIRGIMANVLEAKLAAKPDPSTLPYVEEDVHITVGDGASIAVRIHKPRVVADDGCPVLVAFHGGGFVIGDLEGVGSLCQLFTTLGGIAVNVDYRLAPEHPFPVPVQDCFDVVKWTVDNAKTIGINLSKGFLVGGESAGADLALGVNRLWIDEKQTPKLTGIFSSISGALAEDTVPETYRNRFLSLKQNASAPVVTADSIEFIRDMYKPDPRSPVAYPVISPDLSGIPKTYFQACGLDPVRDCTLIMEQVWKDAGIPTKLDVYPGLPHGFWALFPQADFSKKHQRDQKAGLEWLLHKDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIV6</accession>
    <name>A0AAD8UIV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_580606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363662.1">
        <property type="nucleotide sequence ID" value="XM_060505366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIV6"/>
    <dbReference type="GeneID" id="85389265"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF6">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="232"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="521"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="610" mass="68728" checksum="4657ED39625244D1" modified="2024-05-29" version="1">MRDESSGPIIADGTHEKESQETRPKAPIDPVASNLINPLSTGQSEYTSAPNGRLFYLGTSSNWSFTRRVLNITHQYVHKTPLPSNALLFDGTTYALDWDGYRASEAPEMPALPTQDYAIYLVNAVKFHCGQMFHLFDEETFMKSLYSFYSDPNPRPDPTDPWFIHFLLILSFGKAFTTKTNRGSRPPGHDFFVKAMQLLPDFSVLLKNHVLSTEIMCCIALYTQCIDFRHCSYNYIGQALRIALGEGMHTDMPVQQLGEAYVERCRRLWWTVHILDREITSLFGMPPSIHDDYVLCQLPTYSGSVQRTAALRMRIKLSKVIGSINRKVYGLDGRLNNKFMLGTKEVLASVAEIADELQQSFALPLEKDTSCISRTSAHLHLLHHQCIVLATRPLLFCFLKVRFESQSKCTELLGSSQTVRNLIQMCIDSSQQMVSILDCLQSQGLLETFLPFDLEASFVSASSLLLGPAIDPQCFECLDPSLEKVYSVLDEMIMAGNGIAKYRKFELQQLENMLQRLTPWPSQASEQTTLVDEGRQTHPPGDTSPQDTVVSAMASEHSQHESYSSSIPGNMDEMAYDSGLTMAQLLDMANSIEQEDSEWMSQTIVEHSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIY5</accession>
    <name>A0AAD8UIY5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_620707</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365247.1">
        <property type="nucleotide sequence ID" value="XM_060508210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIY5"/>
    <dbReference type="GeneID" id="85392109"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF237">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ATNE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="496" mass="55714" checksum="F2413A8BB1C3792A" modified="2024-05-29" version="1">METQKATASWHDPSLQVAAVILTIICFLTIPLTYNVLFHPLARVPGPFLAKLNDFWHAYQLYTDMRHETLCKLHDQYGPLVRLGPSTISVNTTEGYQKVYSATSPIDKSPFYQSFTPGFQSSFSSIGAAYKEKKSILSQAFSQKKLDAMEPAFMGHIWKLCEVMKSQGKVNLDDCLSALTIDILSDVCFGETFDLLRNPTEKAKVSDGLVQAAKFVSLEGTLWRWPLLQRMIRKLSYSSTTRGYPAKMAIGAMIKQRQNPSGRQDIFNYLLTAKSPTTDTPFPDRELFGEAIVMFVAGSDTTSTALLTILWHLLAHRDAYDKLALEVRSIVTTHDELSYHKIQHLPYLRAVIEEGLRIFPPNAGFIPRQVLQSDGAFVLHGIPLPVGTEIGVANMAMHRNPIYFERPNDFMPERWIGDGQSAVKDKSAFSPFSRGPRACLGRTMAYMEMSLALAAIFLEMDMEFEDSDLEARQGYTATDSFVLVRPKANIIITPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF9</accession>
    <name>A0AAD8UJF9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_754013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362924.1">
        <property type="nucleotide sequence ID" value="XM_060514423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF9"/>
    <dbReference type="GeneID" id="85398321"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF2">
        <property type="entry name" value="HYPOTHETICAL POLYSACCHARIDE DEACETYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="108"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="39514" checksum="48FBA25A138ED334" modified="2024-05-29" version="1">MEHVVEVGGVRVRMTPVDESPKTAVAFQDLIGQLQLTTALARIPRPISEARRRVQVLVSVDFDAVSGWMGTGQHPNNCLADFSSGIFAGQVGVGRLLGLFERIGVSDKVTWFIPGHSMETFPAETKSIVDSGAEIALHGYCHEDCTKLDTKQEEDVLDKCIALAESLTGKRPVGFRAPLYRIRHETISLLEKRGFLYDTSLSGHDSQLYPLDQGFSLTPVDYSKPAHTWMQPSVQPESTGIVEIPANWYMEDMTPLQFWPNVENSHGFVSVQTIEKMWKDRFTWLWNHGADGHGPGDFVFPLVLHPDTSGMAHIAGAIEDVLLWLKSWGSQVEFVTYETAARSYVEQKGKVISAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJQ5</accession>
    <name>A0AAD8UJQ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_366730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Transport of phosphate groups from the cytosol to the mitochondrial matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364097.1">
        <property type="nucleotide sequence ID" value="XM_060502614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJQ5"/>
    <dbReference type="GeneID" id="85386513"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035434">
        <property type="term" value="P:copper ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000076">
        <property type="entry name" value="Mitochondrial phosphate carrier protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000131">
        <property type="entry name" value="Mitochondrial phosphate carrier protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="90"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="187"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="288"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1724042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="388" mass="42294" checksum="F8107654647C9061" modified="2024-05-29" version="1">MSFLYPRQDTLKGCFASPFGSRSNKAAETTTMAKPTRYQARPEFYGAFSTVDDVKGKAKQLSAEATAEFEKASAKAQSAAGGKIELYSGKYYAACTVGGLMACGLTHTAVTPLDLVKVRRQIDSKLYRGNFQAWGMIFRKEGLRGIMTGWGPTFWGYSAQGACKYGFYEYFKKTYADLAGPDNAKKYQTILFLSASASAEFLADIALCPFEAVKVRMQGGIPSPYKGTLDGISKVTAKEGWGGLYKGLYPLWGRQIPYTMMKFASFETIVEMMYARLPGQKSDYSKAAQTGVSFVSGYLAGILCAIVSHPADVMVSKLNANRAQGEAFGAAMGRIYKDIGFSGLWNGLPVRIVMIGTLTGLQWMIYDYFKIFMGFPTTGGAAPPAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKT2</accession>
    <name>A0AAD8UKT2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">6-O-methylguanine DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_580515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363599.1">
        <property type="nucleotide sequence ID" value="XM_060505360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKT2"/>
    <dbReference type="GeneID" id="85389259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052520">
        <property type="entry name" value="ATL_DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942">
        <property type="entry name" value="6-O-METHYLGUANINE DNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942:SF1">
        <property type="entry name" value="ALKYLTRANSFERASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="3">
        <location>
            <begin position="10"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="14161" checksum="FF92B2D27FD048A5" modified="2024-05-29" version="1">MARTEEAEAFFHAVYTAVQEIPVGKVTTYGHIARLVGTPERPRQVGICLKHLPTDPTSRFNNENVPWQRVINAKGTISPRSQPSGARNQAESLQAEDVEVSRTAMGEFQVDFSSYGWFPDVLPSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULB8</accession>
    <name>A0AAD8ULB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RmlC-like cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_575402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366016.1">
        <property type="nucleotide sequence ID" value="XM_060504811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULB8"/>
    <dbReference type="GeneID" id="85388710"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20281">
        <property type="entry name" value="cupin_QDO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02215">
        <property type="entry name" value="cupin_QDO_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052538">
        <property type="entry name" value="Flavonoid_dioxygenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346">
        <property type="entry name" value="LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43346:SF1">
        <property type="entry name" value="QUERCETIN 2,3-DIOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042137214" evidence="1">
        <location>
            <begin position="16"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40263" checksum="C1513768C27FED10" modified="2024-05-29" version="1">MRFSTLAAGLPLVAAAPQGHSFKQQANSTGKSLILDQAPETSQPYALRKGSGRAVAVGEQVYRFSVTGNSSAGAFTLMQTNAPDSSDLGVLPHIHKVHYENFYCTKGQIQLWAKTNSSGEQARVLTPGDYGAVPHNTVHTFQITDPDTQLTGVIQPGGFEELFIAIANSDFVSPTGSEFVPAASNGSSSGSDPALISALEAFDVYAQLDFNPRRDLVNGSAGGANTWHTAANTLAPDAVTPNFVAKNRGPKYLNADGGVYHLVAPFATANQTASNFTMGTVTLSPLLSNQTATKANLGQPLAFQLEEGSLEVAVEGYDAVTLIQGDVVFVPANVAFTYAASSAFTKFLYVSGGGDGFDYQLLQRAVPWSYATYPIDAGFTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULP0</accession>
    <name>A0AAD8ULP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_779448</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000054">
        <property type="protein sequence ID" value="KAK1724235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364290.1">
        <property type="nucleotide sequence ID" value="XM_060515517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULP0"/>
    <dbReference type="GeneID" id="85399415"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="11">
        <location>
            <begin position="37"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="435"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1724235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="56501" checksum="10E589BD7A5FBAAB" modified="2024-05-29" version="1">MTNYSSITDGNANSIASGSSGEMSRQRRRNTKEGGGQASMLSSVINLLNTIVGAGTLAMPSVVSHMGCMLGVLMIMWSGLTAAFGLYLQSRCARYLDRGTSSFFAISKITYPNAAIIFDTAIAIKCFGVGVSYMIIIGDLMPKVFIGLFASAVAENPYLGERNFWITAFMLVIIPLSFLKKLDSLKYTSIVALVSIGYLVILVIYHFSTDRLKDMSEIRVVEPESAVAFLSTLPVVVFAYTCHQNMFAILNEIKDNSPGSVIGVVGTSIGTAASIYIVVAITGYLTFGNAVKGNIVMMYSATAASYIGQLAIVVLVTFSVPLQVHPCRASVDAILKWRPNRASNANGRSTSPGGRPLLPSSASVRSDHGSSSSMGETRFAILTSVILVLSYVTALSVHSLERVLAYVGSTGSTSISFILPGLFYYKISDPDSIHQQRLHKEDDDADAHNDEEDADPMTTSIASLGSIASHVTDPRQWKRKWRWDLEHIEQDALRKMALALAIYGVCVMVVCLFMNIVFHASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULY9</accession>
    <name>A0AAD8ULY9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364038.1">
        <property type="nucleotide sequence ID" value="XM_060514281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULY9"/>
    <dbReference type="GeneID" id="85398179"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="28839" checksum="428F605B2376D2EF" modified="2024-05-29" version="1">MSFPQFKKLPPEIRRKIWVEALPAPQIYEPDSHEGNWYSDKGTRFFHEYYYTRVREACKEAYEACMSFGRFTFGCFGNSNIRGLWYNDARDAIYYATLGQWHGTNLKASRKMIISVEIALDEFLKTGFEDEKFAACRHLVVALFIDRYLPIGSIMTDDLARMEPLLRAMKDDANIAQTASCSGIIANRFPELAGKDYLTWAEVRGMLLKTREERILANAGKPKMYKRPLLLEAVEVFKNENAQDPERIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMP6</accession>
    <name>A0AAD8UMP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_753034</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363964.1">
        <property type="nucleotide sequence ID" value="XM_060514292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMP6"/>
    <dbReference type="GeneID" id="85398190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000684">
        <property type="entry name" value="Putative glycine-rich RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="118"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="170" mass="17892" checksum="C745D50FDCA0131C" modified="2024-05-29" version="1">MSKLFIGGLAWHTEEGTLRQKFEEFGAVEEAVVVKDRDTGRSRGFGFVRYTQDSDAQKAIAAMNNVEFDGRTIRVDKASDNGPRGGGGYRGGFGGGGGRGGYGAPPVPYGGAPGGYGVPNMGYQQQQPAYGRGYPPQQPYGGAPPQDGYAPQAPYGYADPSQQPQGGRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNH3</accession>
    <name>A0AAD8UNH3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_774123</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366688.1">
        <property type="nucleotide sequence ID" value="XM_060515414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNH3"/>
    <dbReference type="GeneID" id="85399312"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF333">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 12" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152684" description="chitinase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="15">
        <location>
            <begin position="15"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="15">
        <location>
            <begin position="67"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="16">
        <location>
            <begin position="123"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="60"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1726633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="542" mass="60022" checksum="D0F4D6FCB6650945" modified="2024-05-29" version="1">MMSSRSFFSLVLLIFFSCLLASTNAQDGTECSASLPCKVGCCSKFGFCGFGADYCSKSVCTNNCDRKAECDPGGFGKDYVNKTTCPLNVCCSKHGFCGTTEEFCGNKKVSRPSCTVDKSSKFKRVVGYYETWSASRSCNRFYPEQIPRGVYSHINIAFASINPTTFEIVPAKKEDLEMYKRVSALKAKDPNLKVLIAVGGWTFNDPGPTATTFSDIARSAGAQKKFFDSTIKILETYDLDGIDLDWEYPEADDRSGRLEDFANFPKFMKNLKAALKKYEVSITLPASYWYLQHFDLKALSPHVDFFNMMTYDFHGVWDKPNEFVGPYLNSHTNLTEIKGGLDLLWRNGVDKDKVTLGLAFYGRGFIASSSSCMSPGCTYESGTYAQACSAEVGVALNSEIDQLVSEQGAKVTLNKDAAVKIVTWGGNNWLTFDDEETLRLKADYARSLCLGGVMVWAISHDTRAGKYSMALSRVAPRLFTSEMATEEDDGYVTDVEEHKQCRWTNCDENCPSDWTRMMRSGPGAGKNEYMVNGAGCGGRGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNZ5</accession>
    <name>A0AAD8UNZ5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UBA domain-containing protein Ucp14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_701407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363830.1">
        <property type="nucleotide sequence ID" value="XM_060511441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNZ5"/>
    <dbReference type="GeneID" id="85395339"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="267" mass="29731" checksum="0F0ADD247B3C5F3F" modified="2024-05-29" version="1">MSFTNAPVTRTLVLGLVTSSIAASLLDVKHYFYIVVDTHLWRYHQFWRLLAYQLCCTNSSEVLFASITLYHLRVVEQIWGSRKYASFVAVSALFTAVIPPVLLSIIPRVLTAGLFNYMPAGPTPIIFAILAQYHAAIPNIYRYRVAASAAPPTNDQFVGLTFSDKTYRYALALQLALFQWPGSLLGAAVGWIVGHSWRSDLLPVALTTWRLPGWMVGVKTPRRRTEFEGLRRRLEGEGSSATTSGAQGQVDGDAGRRRPAGQDRRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPX4</accession>
    <name>A0AAD8UPX4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_127319</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368487.1">
        <property type="nucleotide sequence ID" value="XM_060501193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPX4"/>
    <dbReference type="GeneID" id="85385092"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="14">
        <location>
            <begin position="30"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="15">
        <location>
            <begin position="294"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1728432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="415" mass="42862" checksum="EEC25FF897DCBEAC" modified="2024-05-29" version="1">MGALERLTQLGGQFSAGGKDKILQKNADDVVVTAALRTPFTKGGKGGFKDTQAADLIAGTLKALLERSKIDPALVEDIAVGTVLAPGGGATEMRAAALVAGFPQTTAVRTLNRQCSSGLQASVDIINAIKTGMIEVGIGAGVESMSTQYGPAAVSEFSELLENTPEAANCKVPMGVLSENMAQDLGIPRTKQDAFAASSYAKATKAQAEGLFDQEITPLKVKWEDPKSGETKEITVAKDDGIRAGVTAESLAKIKPAFAKDGGIHAGNASQVSDGAAAVLFMKRSTAERLGQPILGKFVSAAIVGLPPLLMGQGPAKAIPVANAKAGIATEDVDIYEINEAFASQCLWSAEQLGIPFEKVNPKGGAIAFGHPLGCTGARQISTLLYELKRTGKKIGNTSMCIGTGMGMSAVWVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPY5</accession>
    <name>A0AAD8UPY5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000053">
        <property type="protein sequence ID" value="KAK1724330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364385.1">
        <property type="nucleotide sequence ID" value="XM_060514239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPY5"/>
    <dbReference type="GeneID" id="85398137"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32435" checksum="9742B596E34393CE" modified="2024-05-29" version="1">MLRLDPTVIRITLSDVKRYEGQRKAQDGGGRGNNTHSSLQSSTSSLLHESLRLRFLPDNIRSSEESIEIYNSPAALDGDVGDTIVEDSEKMETSPSDNEDEEQEAENESMRDTYDDRLPGLNAPRLPLPLPFSATARVTTAMNHPGTIIRLPRGSQHGESRCTAYLAPKILSKRAADVISRHNDLSTRQTLRQIPVHNDDAANTWQPYASGDLAEAEQHGRQQPPFLPSIPSPSPRSPRRGERANIPAGGIAEAIRRVGVMVDSEETDEQGMNMWRLAAPPQDEQDEVQDLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQF0</accession>
    <name>A0AAD8UQF0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha beta hydrolase fold family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_576494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365526.1">
        <property type="nucleotide sequence ID" value="XM_060504922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQF0"/>
    <dbReference type="GeneID" id="85388821"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="61874" checksum="6A000636A29ABBDF" modified="2024-05-29" version="1">MLGRTLHEYIFIRACIIPLRYPLLPYAALLIASFLGANYTTSSSSSSSKWLTTAAVITCMAATELIYALFIWLPYTKRLREPASHPSPSSPADRLALFERCMATIPDFERYVRMWFLGADMADIHRDNVRDFLLWAFFDMGEKDVGRASARDGENYDVEVDQYITRSEHLLGRPFKPGRGPAKCLRLTIDSVDTKYRTVWWYAIMAFLDHVTHLSLWFYGFQYYAQPRDKAIFPPRLQQVFASRRSSAGNLSYWHRPHRAEGLPVVFLHGIGIGLWPYVRFLAEITTMRIRGRGQTGVIAIEILPVSFRLTDPPLGKEVFLQQFKQIVNHHAWDKFTLVSHSYGSILSTHAMRCPDLQARIPRAVLIDPVSILLHLPDVAYNFTRRAPSTANEWQLWYFASMDPGVAHCLGRYFFWRENAIWADELVGRTAGSESAGVERQEARQVTVCLSGLDLIVDSHAVARYLAEGGQGQQAGHPAWLQSEHGRRNVAGPKAGPISGMGYESHRSAGSGIDILWFPDKDHAQVFDSPRAIARIVGAIWGDDEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR15</accession>
    <name>A0AAD8UR15_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365689.1">
        <property type="nucleotide sequence ID" value="XM_060504870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR15"/>
    <dbReference type="GeneID" id="85388769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19077">
        <property type="entry name" value="AKR_AKR8A1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF78">
        <property type="entry name" value="PYRIDOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="12"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="35648" checksum="6CB6E9B13DADE1CA" modified="2024-05-29" version="1">MPKLNGQDVGQIGYGLMGLTWRPQPCSEEQAFEAMRTALANGNNFWNGGEFYGTPEYNSSTLLERYFTKYPKDADKVVLSMKGGLILPQLKPDGSPENVRRSLDKILSQLGGRKKVDIFECARRDKNTPLEVTFGVIQKEYIDTGKVGGITLSEVSAATIHEAVKVAKIIGVEVELSLFSTEPLTNGVAAACAQYGIPIIAYSPIGRGMLTGEVKSLDDIPQGDMRRHMPRFQPDTFGINIKLVEQVEALAKKKGVTPAQLAIGWLVALSKRPDVPEIIPIPGATTAARVTENAKLVELTEAEMAEIDATLAKFEVAGGRYPDGAPVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URA3</accession>
    <name>A0AAD8URA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Life-span regulatory factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_231338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366990.1">
        <property type="nucleotide sequence ID" value="XM_060501812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URA3"/>
    <dbReference type="GeneID" id="85385711"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28465" checksum="E57A7626B9E71365" modified="2024-05-29" version="1">MHHSRRKSGNTSMTEKTVTATDPSRYGKRPSTLTRRQTPQKLGKNPRDRDREREQQDSWDDERESFPQFCMTCEKQFVPQDDRFLYCSESCRKHDQQTASTGRTMSQPHMGNYPFYAACNPEPRDIVPRASPSRPNSMHFSPPTTPGATSGAQYSSAISALRSLSIRPPSPPSPTSSHASIWPFTKSSTNSPSTSYNRGSNSFFPATYDGGYAANGYAYNYSSSGMDRPLPTRRPTGPGYSRPKSIELVTPMVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT94</accession>
    <name>A0AAD8UT94_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_697609</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365990.1">
        <property type="nucleotide sequence ID" value="XM_060511388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT94"/>
    <dbReference type="GeneID" id="85395286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="55138" checksum="D077FBE2A0147261" modified="2024-05-29" version="1">MSREYLAYAVSAFIAYSVVSIARQYLRLRHIKGPPSAGFSKWWLVRAVGGGRTHLDFYEACEKYGSIVRVGPNDLITSDPDLMKRMLNVRTTYKRSNWYDGMRLKPGQDNVLSTRDDELHNKLRSKMAAGYSGKEVEDLEAKIDQNVLRLIGLIEKYASRDEAFDFGAKAQYFTLDVISDLAFGEPFGDLATDSDVHEYIKTMEQNMPTILVTSVLPWLLALLSSPIFRSMMPSEKDAIGVGKTMGIAKKVASERFGPNKKVQKDMLGSFVARGLTQAEAESEILMQLLAGSDTTATAIRATILHIITNPQVTATLRAEIDAAKLSWPIVSDAEAREMPYLQAVIKEGLRIFPPVVGQMSKEVSNGGAGDDFKGVHLPEGTRIGYCAWGIFRRQDIWGQDSHVFRPERWLESDVERLRLMEGTLELVFGYGRWQCLGRNVALMELNKVFVELLRRFDLVVIDPTNPWHSVCSGVFLQSQYWMRGCTRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUE3</accession>
    <name>A0AAD8UUE3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_750073</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367339.1">
        <property type="nucleotide sequence ID" value="XM_060513872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUE3"/>
    <dbReference type="GeneID" id="85397770"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1727284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="58826" checksum="6AAD475D31A776B6" modified="2024-05-29" version="1">MNTATVTSLESSSTTTTSSSLHNKHNGTSNGNSNPKAAVKPTTPETNRTTDELRRAIQKKYRHVAAVHSKSRPSTLSHDSNTAPSFIGFRNLMIIVLIVGNLRLMMENIQKYGVLICVRCHDFRQQDLALGLGLYLLIPCHLFAAYLIELAAAQQARGLRAKSKDGAASPTEDQRARFNSTWKVIAWIHAVNITLALTVTSYVVYFHIHHPLIGTLTELHAIIVWLKTASYAFTNRDLRHAYLHPVKGELAAMPEIYQQCPYPQNISMHNLAYFWWAPTLVYQPAYPRTDKIRWVFVAKRMAEVFGLGVFIWFASAQYAAPVLINSLDKIASLDVPKILERLMKLSTISLVIWLAGFFALFQSFLNALAEVTRFGDRCFYEDWWNSESLGAYWRLWNKPVYQYFKRHVYSPLIGRGWSPRAAQLAVFFASAVLHEVLVGIPTHNIIGVAFAGMFFQLPLIALTTPLEKMQSPTGRMLGNCIFWVSFTILGQPFAALMYFYAWQAKYGSVSRQMAWNSVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVG3</accession>
    <name>A0AAD8UVG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_170850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368091.1">
        <property type="nucleotide sequence ID" value="XM_060501469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVG3"/>
    <dbReference type="GeneID" id="85385368"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033934">
        <property type="term" value="F:glucan 1,4-alpha-maltotriohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004574">
        <property type="term" value="F:oligo-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000025">
        <property type="term" value="P:maltose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11333">
        <property type="entry name" value="AmyAc_SI_OligoGlu_DGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000064">
        <property type="entry name" value="Oligo-1,6-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000087">
        <property type="entry name" value="Oligo-1,6-glucosidase IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000003">
        <property type="entry name" value="Probable alpha-glucosidase (Maltase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF222">
        <property type="entry name" value="MALTASE MALT (AFU_ORTHOLOGUE AFUA_8G07070)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="9">
        <location>
            <begin position="21"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="584" mass="67681" checksum="6884954F6492D741" modified="2024-05-29" version="1">MGSITLNNASRAWWKDAVIYQIYPASFKDGNGDGLGDVQGMIDKVDYLKDLGTDIVWVSPMYASPQVDMGYDISDYQDVHRPYGTVRDMEVLIEECHKRGMKLILDLVVNHTSDQHKWFQESRSSKTNPKRNWYIWKPPRYAEDGTRLPPTNWRSHFSGSTWEWDEPTGEYYLHLFAKEQPDLNWENEETREAIYENAMRFWLDKGVDGFRIDTVNMYSKGVDFRDAPIMNKNAYEQPAYMIYCNGPRIHEFLREMNAKVLNHYDTVTVGELPHTPDPKHVLKFISAADRQLDMVFQFDIVDLGQGVGYKYQAQKWTLPELKRIVAKWQQFIEGTDGWTTAFCENHDQGRSVSRWGSDKPEWRETSAKMLALMMCSQTGTLFVYQGQEIGMTNVSRSWGIEDYKDIEALNYYDDIKKEFGEGSDMLKYVMDGINLLGRDNARIPMQWDDKPYAGFTDNKDGAWMRVHDEYRSINVAKQEKEPGSVLNFWREMLKLRKEEGDLLTHGAFELFDVENKETFVYKKSRGGRSAVVVLNFTGEEQAVEVPSEGGKIRVGNYDDVKERVASEGGKTVLRPWEGRLYLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVH6</accession>
    <name>A0AAD8UVH6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_128312</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368504.1">
        <property type="nucleotide sequence ID" value="XM_060501197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVH6"/>
    <dbReference type="GeneID" id="85385096"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="243"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="901" mass="100776" checksum="2CD62B6FA4A1B430" modified="2024-05-29" version="1">MMPLQSIEGQPHGGSGIAGENGEARQQKPKTLPCKYCSKRFRRVEHVQRHERTHTKEKPFACGWARCGKTFGRRDLLVRHEKLVHLNEGSKENNRPRKTSSSTHNPPSSSDSHVEHEMLGVQRPPQPQYHQESITAVASTMAPDPRMPGPARAAACNLDLLSDAALASEVNPMQQPMMAEMGRPPSDHTRIKSYDESMGYPERPREDQNMLAPGYVPQPQAAPYDDYHIFLDDFAPSSHYLPPPFESDQQMGGLWPRGDMHHRGPSKPSSQFPSRFPSVQPDGREGMEGGPRSHEESMRAPLRISAVDHTVIKNRLEEFSSVIPNDFVFPFRHTLTRFLEGYISGFHEYLPFLHIPTLTPAEMAPELLLAILAVGAQYRFESHRGHALWYAAKAVALEQIRRRHSHEVHALLPTPAAYSPHSTRPSPSSGFRHTFASAQQDRPMTQDTHREPFSPNTPQARLETTQAVLLLFAVGLWGAKAILHEALSLQSHLAMLVREEGLIAESSPAVAPDWETWIRLEGATRTKLIAYCFFNLCSIAYNMPPLILTSELGLFLPYPSRLWRAESAWQWQEDRQNYPSVEITVHDAFSRVLTTSPQGLPPHMSSLGNYVLIHALLQHIYLLKQTSFALSSPFGPQRGLKPEDVEEVTAALRIWQVSFEHRHQLRAADAGHVGNSDSFPGGPVAFNSTALLRLAYIRLYTEIPPNRSLETRDHMLVASSLSNMPLLVRTLRLHRAVFQAIHALSMLVKAGVNYVARTKSLEWSIQHSLCNFECAILLSKWLLTLASIGPNDPPATPEEKNLLQSVRRMLDETEFAVPIDPSLGGPTAGQPANNEVSANDSTRLRQLAAAVIRLWAETFKGSHIFDMVRVMGSSLDGYADLVEKPRDRTPLGRIAHDPNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVV8</accession>
    <name>A0AAD8UVV8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-nitropropane dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_716807</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368808.1">
        <property type="nucleotide sequence ID" value="XM_060511881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVV8"/>
    <dbReference type="GeneID" id="85395779"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF34">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="33215" checksum="9EBA8096F46CE59A" modified="2024-05-29" version="1">MAISRLVSWFPHVKAPVIINAPMLGSAGAAMATEVHKAGGFGLPLGVGFITSHETAGHFTANVLPILVRHGVAAAWLFAPHPETKPHGEIIAALRGKGTKVFVQVGNVAAAREAAADGADVIVAQGVDAGGHQFSRGCGVVALVPEVKAMLASEFPDRDVAVVAAGGIVEGSGVAAALALGAEGVVLGTRFVATDEAMSAQLHKEVIVRTKDGGLSTWKSEFHDRLVDNKLWKDGYDGRAIVGDIHREYHALGGQTATVEESRERLRTGWSEEEGKKMIGKWAGAGLGLIDEIKPAGVVVTEVREAARKRIQELAGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWD5</accession>
    <name>A0AAD8UWD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_570193</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368601.1">
        <property type="nucleotide sequence ID" value="XM_060504277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388176"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000055">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000066">
        <property type="entry name" value="ABC multidrug transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="537"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="953"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1052"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1128"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1167"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="284"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="621"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="919"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1232"/>
            <end position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1728546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1487" mass="162703" checksum="AF9AE0508667E23F" modified="2024-05-29" version="1">MWVPQPACSSGLDNSLGPWAGELCRGGFDFTLFFEEVILAVPLQSLLLLLLPTCALRLARSDVKVVPSTLRWFKASASISLAALNFALLILWITAPSTTITHTRATIPTAILSLIASIGLGLLSWLAHQRSVRPSFVLSIYLFLSILFDTARARTLWMLGPHQTIPAIFTCTLAVRAVMILLESTEKRRILVPEHRGYSKEVTSGTFNRSVFFWLTSLFINGYRNILHLDDLYPLDPKLASEPLYRKLADAWDQVPDKTVPGALFSTWLRAFAGPLSAAIVPKLFQIAFNYAQPFLIDEAIRLASQPQQQPYNNHGFGLIGAYVIVYSGIAVSTGQYDWRNQRAASMTRGSTTALIYRKALRLNLTSPNVSPSGALTLVGTDSETISQGITQLHEVWSGLLEIGIGIYLIYRQLGAACAMPVALVFVVLLATAFLAVPTGKASAEWIKASQDRVSTTSKTLGNIKWLKISGLNDVAFSVIQKLRTVELEVSKRFRVLLGISMMFLICTPIWSPILTFSTFVATAARTGDTLTIQKAFTAYSVLILVNQPLVGIVMGLPLLASAMASFQRIQDFLNGKERVDARLASEGVKIAGAGKSVTESPKAAGLGPDVELSDMRESELLVADLAPNIIASVKGTFSWSDDSKPVIDIDNWNIRGRAFTLVLGPVGCGKSTLLKCLLGELSSFEGTILTNFSGVTYCGQTAWIPNDNVRNIITGQAAFDSTWYHTVIKACALEQDISSWPNGNSTVAGTKGISMSGGQKHRLAIARALYARQELVVFDDVFSGLDASTEDIVFNNLFGSSGLLRHTDTTVILASSDSRRVPLADDVVLLNDGGRIIDNEMAMKVGQSTEYPNEHAGISASDSAAPLPMITSNDKPPGTVLGLLEDQADSARQLGDWGMYSFYARAAGWFSLSTFAGAMIVFAFCDSFPDIWLKWWAESNEKKPNQDLGKWLGVYAALGVGSVASVLFGMWQLFIVIINKSGVYFHGVLLDTTSRAPISFHSSVDSGITVNRFSQDLQLIDMELPAAALGLAVGVAFGAARFIVMSVSSRYMAAILPFLIPAFYAIQHFYLRTSRQMRLLDIEHKAPLYSQLIETLEGLATIRAFRREDGFEKVNFHRLDDSQRPKYLLACLQSWLTFSVDMVIAVIAVVLIVLVTTLREQIGPGFIGVALTNVLAFSGCVKAIITSWVMLEVSLGAVARVRNFSLTTRSEDDSRVQLAEPEGEWPSQGAVELRKVTASYASSGAVLKDVDISIKPGQKVAICGRTGRQVIPFPHLYQSKTSNTPSSGKSSLILCLLRMMQVDSGTITIDDVDIATLPHEYVRSKIVAVPQEFYIFDGTVRLNLDPGQTASDEIIMAVLKRVQLWDKVEERGGLDAVIDDKFFSQGEAQLLVFARAMLRKGRVLILDEITSSLDDESSRIIDEVLRSWFRDWTIIAIAHKLESMMDFDRVAVVDSGVVVQYGEPRELLGSESSFKALYERSSGVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7Y2</accession>
    <name>A0AAD8X7Y2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Thiol-specific monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_658343</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000276">
        <property type="protein sequence ID" value="KAK1703675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357338.1">
        <property type="nucleotide sequence ID" value="XM_060511033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7Y2"/>
    <dbReference type="GeneID" id="85394932"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000138">
        <property type="entry name" value="Flavin-containing monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1703675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="55323" checksum="DCAFBB41DC8F4020" modified="2024-05-29" version="1">MSPMYMEDKLNIDRVAVIGAGPCGLAAAKYLLAEKKFSKVQVFEQRDTVGGVWTYSPLNVIDGDFSIPRTQPTKNPDTAIAVEGHDAKQFVSPVYDYLETNIPHTLMNYSDKKFPSNASLFPPHQTVKKYLEDYAEELKPIISLSTQILSIRKSTGGSEVYWEIESLDLKTNETNTAQFDAVFVASGHYNDPFVPDIPGLAEFDKAHPGSISHSKFYRNAEQYKGKKVIIIGNSASGIDLSAQISTVCALPIIVSEKTIPNTPAEDRSSWAQPVPEILEFIPENRQVRFANGETESEIDGIVFCTGYFYSFPFLRDLSPPVVTDGAYARNLYEHLLYIDDPTLAFAGIPQRIVPFPVSEGQAAYVARAWADRLRLPSRGVMRQWEARMLKDKGESKMLHNLAFPKDLDYINMLHARSLEAEKREGLENDGVGKIPPYWDDEKRWTRERFPLIKIASRKLGERRHEITTLEELGFDYKAWKAGLNEEEKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X842</accession>
    <name>A0AAD8X842_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_713866</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000255">
        <property type="protein sequence ID" value="KAK1704893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357503.1">
        <property type="nucleotide sequence ID" value="XM_060511647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X842"/>
    <dbReference type="GeneID" id="85395545"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF35">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1704893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="31760" checksum="9F072D9E5BBF5AAE" modified="2024-05-29" version="1">MDSPTENSPGEFVFYHYEPSLPAACVFIALFGISSALHLYQMIKLRAWYFVPFLIGCCFEIVGYIGRALSATETPNWSTTSYTIQSLTLLLGPALLAASIYMVLGRLIRFLEAEHLALIRTKWLTKLFVLGDVISFVTQGAGGAILSRAKSLSDVDLGENIIIAGLAVQILFFGGFIVVTCLFHYRINQNPTDACNSASLRWKPIHWILYGASLLIMIRSVFRVAEYVTGSNGALMASEMYIYVFDAALMLLVAAVFNVFHPGTIIQTENKLTAISESSVPLDLQTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8S8</accession>
    <name>A0AAD8X8S8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_657214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358659.1">
        <property type="nucleotide sequence ID" value="XM_060510946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8S8"/>
    <dbReference type="GeneID" id="85394845"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1709748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="114" mass="12565" checksum="75B6D762A389B567" modified="2024-05-29" version="1">MVLAPLRCFCCFCCSSPRFMSVPHTNFPRKFETRTTLPNGQRPPVSRQSPVVFLSLKTAAGEHQTERCPINTTDIRPRHGGTWAPAFTSKQSGCAAGAEYAATYVQSWTSVIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X941</accession>
    <name>A0AAD8X941_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_710857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359049.1">
        <property type="nucleotide sequence ID" value="XM_060511594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X941"/>
    <dbReference type="GeneID" id="85395492"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="56592" checksum="FED6FA3C48C50C64" modified="2024-05-29" version="1">MATQQISSATPISAADDAASRRAKKRELDRRAQRAARERNKNRIAYLEATIQAMSEQEQNAKIASLMNQLSDMTRQRDTLSKTLSSLETTIQVHREGERADSLQDRASQPRDTASNCQSWPGAHESSNAFDIEVEDMPLDVFTPDISAITWGLPVSDVAVHTLATETELANRVPASSTLTMAGNPNLECLPDSPPPRHQGDGVIVPEPDSACECLGSRQDPQSPGSSTTSLWRSANEALGVSEKLSRNVLNMEDEMSDDIPVRVILEGWDAVERSGKLPPLWKRLRQTDTLQFRNCPDTERLAILRLMHRLLRYQAEPTVEQCAKLPAWYLSRPSQSLPHSSAIDFFVWPGVRERFVFSQHQYCSNLFWEVFASSFRIMWPFEFRDCYRRNIETRRYCVAPEFEDRIRDINSWTMSSDFFNHFPEMYADIPAYQEVPRLLTWKDARDSRLRQRGRVKELETESSPRSRRNSDMDMLSLTTVQNWPAGGFLLSDPSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X980</accession>
    <name>A0AAD8X980_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_758505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357716.1">
        <property type="nucleotide sequence ID" value="XM_060515044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X980"/>
    <dbReference type="GeneID" id="85398942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="242"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1705937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="390" mass="44198" checksum="52A959B3DF040F4E" modified="2024-05-29" version="1">MGDMLAWYIVIFLGSAILTTISIYNSEFITNPTISFLVHITTSIVLYFTSLTCLALTAIEDWRLQARLARKKGRGLEPFRFFPKEHAIFVTRATGLAAGAYVMALPLLMPTDDVISQVCLRIPTFFYACKCWDLTIARVRKPPVPRVGKEEVVYGLTSWRPVASYVWRLGSETRYASFNIAVDESKRKSIPKSAAWTYGPLLVVPLTYLFPVTELKVMCGLLAIQHGLEGIHFIFHPHCPNKLFFQPWAADSFSSFWAIHWHHGAQPFLQHLGYVPARALFTRLFGKDAGKAAGVLAAFSLSGVWHAWCGVVLTLDEYAWTQAVGLWTVFMVQGVGCLVERWLLRNESWRTGRRRQMLTALCWMASVESAAFWLRYGEARAKRPQGWTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9R8</accession>
    <name>A0AAD8X9R8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_548944</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358331.1">
        <property type="nucleotide sequence ID" value="XM_060503472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9R8"/>
    <dbReference type="GeneID" id="85387371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1708453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="89" mass="10345" checksum="6E34A84EBAE3AB05" modified="2024-05-29" version="1" fragment="single">PQQPRQLPYVCTGNPNCTRSYEKKHELNRHMRKHSRPCACPVENCTAKFADKKSLDRHKATHGIGRGEFDCPECTETFTRADNLHRHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAF5</accession>
    <name>A0AAD8XAF5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Regulatory P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000269">
        <property type="protein sequence ID" value="KAK1704177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357384.1">
        <property type="nucleotide sequence ID" value="XM_060506757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAF5"/>
    <dbReference type="GeneID" id="85390656"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04312">
        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041994459" description="Regulatory P domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="52263" checksum="E587D676B9409869" modified="2024-05-29" version="1">MKAITLATLAVSALLSGASAKEIAPSELVSEIYDSGVIHKDLMARKKASWDRQREAGEMESTKYTSRLAEEGPVSCVNGVAEVIPGDANNTFKCNKVDFYDFKSHSDLGSTAGEGSSSWGWTSPDGREFAIIAQADGAAFAEITSAGKLVYLGRLPQYSTQSIWRELRGYKNYVVIGSEASRHGVQIFDLTKLLDIDPASPVTFSNSRDLTGYWNGLPAGSTHNIVINEEKQYAVAVGAQPRSSACRSGLIFIDLSDPANPTSPGCAAGDGYVHDAQCLVYRGPDEKYFGRDICYGYNEDTLTIYDVTNKNETNIISRTSYEGASYTHQGWVTNTEWQEYLVLDDEYDEVDATGPAASGYPITYFWDIRSLEAPKQTGYYRSEAYGIDHNQFVIDGLAFQSHYGAGLRILDVSSLPDDPTGGGVSEVGFFDIYPENDNEPLGGSIDFVGTWSHYPYFKSGHILINTIERGAFVVKRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBF9</accession>
    <name>A0AAD8XBF9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_758394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357835.1">
        <property type="nucleotide sequence ID" value="XM_060515026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBF9"/>
    <dbReference type="GeneID" id="85398924"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="36"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1706435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="54923" checksum="ED0DD0A413E53195" modified="2024-05-29" version="1">MLNFRRKKSAESEATAQEAVAVDDAPRQPFRKAIVPVIACGAGLFSDGYINNVIGSVTTILALQYGDLYKNSNAKKYVGDIAFAGTVVGQLAFGWLADHWSRTNSLLVSTVILLVFTALAAGSYYKGDDIGMFNILAAWRFFVGIGIGGEYPAGSVGAAESTGELKSGSRNLWFIMFTNTMIDWGFVIGAFVPYVVAAACHNGHYSTIWRTSLGIGVVFPMFLFALRLFVKEPEASTKNSMRYAKTPYLLSLKFYGWRLFVVSLIWFIYDFSAYSFGIYSSTILSNLYGETAPLTTVFGWNTVINLFYIPGTMLGAPASDWLGPRYALALGVFLQAVVGFIMAGDYFNLSQPGMVGGFVVVYGIFLALGEFGPGNNIGLLAAKTCATGIRGKYYGVAAAIGKIGAFVGTWVFPYIQAAGGDNAVASAQYPFWVSSSLCVLSAALAIFCLPHIGQDTIALEDARYRAYLEANGYDTRQLGMKRGESFENTDAEIPAEGLAETTKGEKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBG0</accession>
    <name>A0AAD8XBG0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361569.1">
        <property type="nucleotide sequence ID" value="XM_060508919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBG0"/>
    <dbReference type="GeneID" id="85392818"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041984586" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="16035" checksum="C1D04FE621BF6042" modified="2024-05-29" version="1">MLKMVILHLLTLGLTATAMASPASSNGATPTDPKDTLVRKDDWDKYLKYKARLGTQASEQGVVQRICDLVLCLGPNHTGECSLWCHYKGELQSFEEAKQREITMSTYFTMSDRCNFYAYVVFRPSQHRIMNQKADYGMQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBK4</accession>
    <name>A0AAD8XBK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_758277</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000217">
        <property type="protein sequence ID" value="KAK1707122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357970.1">
        <property type="nucleotide sequence ID" value="XM_060515008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBK4"/>
    <dbReference type="GeneID" id="85398906"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF162">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1707122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="56675" checksum="2048A36071A38057" modified="2024-05-29" version="1">MAFTSPLSTWSMGQQLSLALVILALAFVSVIIYGCFLHPLRRIPGPFLAKFSPLWIMRALHRMRFNSELQALHQQYGRVVRVGPNEVSFASLEAETAIYAKQEDGRFSKDGTFLTLFSDLVLNAPTLITIPDPALHRKLHKVIQQAFTPQALARQEPIQKLHIDMAMSEFEELAKSGGTVDIADTLETMFWEIIGDLAFGEPLMSGKRPTYESLKQLGKSTMPMVEALSFFLALPGIAPILGIARCLITALPFPSQLSKLVPSSKLRDCAERQDGREDFLTAIMGSEKQDLTLDADAFFSNAMGLTLAGYQTTATTLSATFYHILRYPEAYNRVCFEIRSTFASDEEITGARLGRLPFLNACIRETLRLLPPANGKTAQRTAPSCTIDGVHIPAGTTVSADLYTIQRSPEYFADPAVFRPERWLDGAEDTEFKGDNRAAYRPFLIGSRACIGREMAQQSIRLIVGKLLWKYDFQQLGQDGFVWERDAGSSLIYTDYKVMVHVMKASGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBL6</accession>
    <name>A0AAD8XBL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromatin remodeling complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_585839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361282.1">
        <property type="nucleotide sequence ID" value="XM_060505877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBL6"/>
    <dbReference type="GeneID" id="85389776"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF5">
        <property type="entry name" value="LOCALIZATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="494"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="447"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="601"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="638" mass="69162" checksum="20D1A115EE4286B7" modified="2024-05-29" version="1">MYSTQPNGADSATINPAALNSPDLLNASTRGIKRSRSPDNFQGNPSAGIAGDSNPRKRGKSSKSRSSGAISETAGQAPVANMPQNIPPPQTPQNQSAPLPGGQAVNYAPAQASPPPKTTPTKTTLKALPTVRDHTTDQLNPAGDEYLPREIDEFGEKKVMPNGQLLGGREYRCRTFLVPNRGDKLFMLATECARVLGYRDSYLLFNKNRSLFKIIASQPEKDDLVSQEILPFSYRSRQIAIVTARSMFRQFGSRVIVNGRRVRDDYWETKARKQGFTEADPAGEKRPGAAKAREAAAEAQNQVLLGGPHGEIVYSNTPSQFPGAPQPQIVQPGMLGAPTGTTTRMPVITLGSELSDNRPRDYSGILKGGPRQEITGPAYQDQTRPAQIGEVHAQAHHAAEYNRSLNQQREMRGDYLQGIWRRPHEQPQSTNLVQNVATSEAAVPATRATQSPHTTASNMPSQSGIVPNQSPQMMMTAPPYSQSIHAQNPISQAPMRGMAQPSAQKNNKPTTLPAAGSASSMPQGAQGYHYPGTGQMWPQTQQTPQQHNYSGYTTQGQQPHQQSPAPQLRHATSGVQPGMQFSGMPGMGQSYGAAGQGIYPTDQTPRQYMPQPNQGSPAVTQAWSNQQTPAQWWSNQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCC3</accession>
    <name>A0AAD8XCC3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_657201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358645.1">
        <property type="nucleotide sequence ID" value="XM_060510943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCC3"/>
    <dbReference type="GeneID" id="85394842"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1709734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="588" mass="64836" checksum="57F87445268CB73F" modified="2024-05-29" version="1">MGLFSKKAPVEEQVAAEPTGSPHYDEKTTGEHPGDRSSDDEPISKDLQAGVAKVEAMTTVWTKRDLIIAYTLIWLFYVVTSIQEVSMRVLSPFVTSSFAMHSLTATTGVMSTLIAGLIKLPLAKILDTWGRPQGLGIMLICWILGFIMMAACNGVETYAAAQVFYSVGSQGISYCITIFIADTSTLKSRALMLSFATTPYIFITWAAGPITDSILREDGIGWRWGLGMWAIVAPVVIGPLVLLFLWNQHKAKKMGVIESRGSIKNISGAKILKFLIDVDALGILILATGMALFLLPFNIYSYQSDGWRSPMIIAFIVVGFFLIIGFVAYEKFFAPVTFIPFSLLMDRTVFFGGMMFVFVFFNSAVWGSFFTSMLMVVWNTSTSQTTYISNIYRTGSCFFSIIISWLIYRTGRFKPFALFFCIPLMMLGVGLMIHFRQPDQPLGYIIMTQIFVAFAGGPTVICGEMAMLSPSDHAHVAVIMAILDLFGSIGSTVGYTVATAIWTGTFRKNIAKYTPAGTPVDTIYGDIYQQLSYEVGSPERIGIQRAYGDSQRIMLITSICLLVGALGSVAMWRNLNVKKIKQVRGNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCF7</accession>
    <name>A0AAD8XCF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359528.1">
        <property type="nucleotide sequence ID" value="XM_060506268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCF7"/>
    <dbReference type="GeneID" id="85390167"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052512">
        <property type="entry name" value="4CMD/NDH-1_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33570">
        <property type="entry name" value="4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33570:SF2">
        <property type="entry name" value="CARBOXYMUCONOLACTONE DECARBOXYLASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxymuconolactone decarboxylase-like" evidence="1">
        <location>
            <begin position="46"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="153" mass="17215" checksum="A64C2CC780659CDF" modified="2024-05-29" version="1">MSSENSKKLRAELFEAGLKNRREVVGEGYVETAMHNGSSEFAFAQQELITEWAWGNIWSRPGLERKQRSLLNIGMLIALKSWAEFGIHIRGAIRNGLTELEIREAILQATVYCGAPAGVQAMKVADEVIKDMIEKGEHQRQLSEVSPNYKKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCM4</accession>
    <name>A0AAD8XCM4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362859.1">
        <property type="nucleotide sequence ID" value="XM_060510632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCM4"/>
    <dbReference type="GeneID" id="85394531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="324" mass="35691" checksum="FD17666D8DA89360" modified="2024-05-29" version="1">MLGEMGEGKGKPPAKVGWQVRLCRPLLPLGSYHAIIDKVRKDQPDRGVKEGRSYHHSLSACLGIYLSNTFLFSHSDYLNFTQWSHPPLPTIHRKTYSEMDVAFRRVGTPVTEAPEVHASQARSLIKVRSMDGKACQSIPPQPRIRYNTLPYEGQSTRTPIPSLSYSVPITLVAQWAESVSKLPFSPAPRPLSSQPASPKTSTRSFTDDSTSNESQLIPSHLKTELVLTIGHLIALGTSSASPQNTPIRRSQTPSGSYFHVPPPTSESSMIISGPVHLSRSREGKAEKLSRHKRLPLIHHPRGSSLSVFLSYTRGPTTITTPLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCP0</accession>
    <name>A0AAD8XCP0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359783.1">
        <property type="nucleotide sequence ID" value="XM_060510858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCP0"/>
    <dbReference type="GeneID" id="85394757"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="176"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="425" mass="46298" checksum="45F14C7E0E1296CD" modified="2024-05-29" version="1">MSTLSLFQQIHLQSLTANLAGSIVGPEWILQDAMNIAAKRMVKKHLSQYGWDLTWGPRVWKSETSKWYEGLNNCWMVMKASNVEYPDGTKFDTYVVAIAGTAVFSIEDWKFEDFGVDKVVDFNAYTKTFKTGSAEQPVGVQNPPFRDIPYGAWGTTLGAWAVVTHASPSGNPGAGTNLLEYLANLKKSPGDFRVIFTGHSLGGALSPYLSLATKANNLVPGVADIAGDILALPAAGATPGEQLLSDAYSKLSKVSGPGGYQLWNADFYNTLDIVPNAWSTDDTQDRNIDKIVSIYGPLQGKILTQIQGLVQKAKDRAKSSGFTYIPIEGNPFKGTPPAKTPTNFLSFMSEAVLQHTKAYHNAVNVSDELVDLYDTIISASGVKKKSARILAKEMPVLCNVDDSEWDDNSDETYPFDCILTGERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDJ8</accession>
    <name>A0AAD8XDJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid/polyamine transporter I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_707538</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360803.1">
        <property type="nucleotide sequence ID" value="XM_060511548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDJ8"/>
    <dbReference type="GeneID" id="85395446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF13">
        <property type="entry name" value="THIAMINE TRANSPORTER THI9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="532" mass="57919" checksum="573FC978738F7DEC" modified="2024-05-29" version="1">MAATERQDEGAAKNVNTFQSDVEDESTKDARVLENLGYKPVLHRTFNTFHNFATTFAALYFIGGVRVTFSTGIAAGGNLAYWTSFIVTCVFTFITAAVIAEICSSLPLAGSIYLWAAEAGGPRFGRFFGFIVAWWSTTAWTTFCASNTQAAVNYMLSEIVVFNLDFPSDSSSVKFRAVQWITTEVMLALAAIWNLLPPRYFKWIFYLSTGFVLLDFVLNMVWLPVATSKSEYGFRSAHDAFMTTYNGTGAPAGWNWCLSYLATAGILIGFDASGHVAEETKNASVAAARGIFWSTVVSGIGGFVVVILFLFCVPDADTLFSFGGAQPFVPLYAAILGEGGHIFMNIVCIVALWFNTAIAILAASRLVFAVARDGVLPWSPWVAKVVDGQPRNAVLVVWGVASVITCTILPSSVAFTSLVSAAGVPSAAAYGLICLCRLFLTPKQFPKPAWSLGRLSKPFQAIAVLWNGWVVAVLFSPYAFPVEASTLNYAPVIMGIVTIFAILSWWFIPAERWLPSQRIQETLLAGERPIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDM0</accession>
    <name>A0AAD8XDM0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1688 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_733841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360878.1">
        <property type="nucleotide sequence ID" value="XM_060512928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDM0"/>
    <dbReference type="GeneID" id="85396826"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1717391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="47388" checksum="5945C89B224BF8F6" modified="2024-05-29" version="1">MDSEVEYLLSLRAIRERAKIVGDVAKAGNLSHFEVREDKLDEVVDFVASVIKRDYGPDKFHTIPPHGRWQHFEVGNVPRVTNIIEEWKANGSDETEVTRRLIDLFFVSVLLDAGAGDHWRYKEPKTDQVYERSEGIAVASLHMFNALAYTTSTDKANPIVDGKGLERLETSALAGGFQVSDSNPMLGVDSRAGLLRSLGQSLLAHPEVFGADGRPGNLVDYLVKSAKGSSKIDVLYLWDILQTLLIPAWPKDRTTIGGTPIGDAWPLSTLRKGAEAGSSDSPAAGIQPFHKLTQWLTYSLMVPFQRVLGLEWANADSLTALPEYRNGGLFVDMGVLALKKETLERGLKASGSELPMFEAGDDVIVEWRAMTLVLIDSLYGKIRSRMGEGVELSMAQLLEAGTWKSGRETAAKFRPQTKSSPILIKSDGTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDM3</accession>
    <name>A0AAD8XDM3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_626720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363352.1">
        <property type="nucleotide sequence ID" value="XM_060508582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDM3"/>
    <dbReference type="GeneID" id="85392481"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07406">
        <property type="entry name" value="MPP_CG11883_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041821">
        <property type="entry name" value="CG11883_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="5">
        <location>
            <begin position="323"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="636" mass="70750" checksum="524DE88C5C03C44F" modified="2024-05-29" version="1">MPKNTPAPDEPVVTFSSGSNAPVALRLLHLNDVYHLEPASAEPVGGVARFITAVNEYRSHERYQGQPELLTLFSGDVFNPSLESSVTKGEHMVPVLNKIGVDCTCVGNHDFDFGVKQFEHLTAKCNFPWLLANVLDPALGENVPLGHAKHTHMITSSNGIKIGLLGLGEREWLETINSLPPNIIYKSASETAKELVPQLRAQGADIIICLSHQREPNDNKLAEKTEGLIDIILGGHDHYYAHSFVNGTHVLRSGSDFKQLSYIEVRKKEDGSGKWDFDILQRDIVSSIAEDQETLKLTEELTSKLKHSLAKSVGWTASPLDARFSTVRMKESNMGNFVCDVMRHYHNADCALMAAGTIRGDQIYPPGAIRVRDITNCFPFEDPVIFIRVTGQQLWEALENGVSQYPAQEGRFPQVSNIEYTFDPSKPAGSRIVAATLGGGPIEPEKKYTLATRGYMGRGKDGFTSLLVEPEGGTAEEIVCEENGILISAMLRQYFMSLRTVGQWKNLSEHWVKVAEKCHSPVEPRKMWETPAETGTSDPKPKVESKSWAEWMVKRHALNIKPPKDDSDEEVDSEDEVDSVAQIDMEMLIMRKFFARWASKAGVKAEVCDPLHEGEFTVDWTRVIAPVLEGRIKMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDR6</accession>
    <name>A0AAD8XDR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_753509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363472.1">
        <property type="nucleotide sequence ID" value="XM_060514359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDR6"/>
    <dbReference type="GeneID" id="85398257"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="604"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="756" mass="84313" checksum="86A7B4BD848A7DEE" modified="2024-05-29" version="1">MFHSFDSHRSPEGSAGSSPTTSRKVNRSCQECTRRKVKCDGGHPCASCQYYKVADSCEYRQRSRRHAVSRSTLEKTSEQLRAQSSVLQKLFPDVDVNDLVGKSRAELLSLLPRESLFALGSSVPQADPSPAGVSAADEDDDDDRHDDSAQNSENGDAANERRWDEPAQQPATLGSSDDINAVSLATDQHRRSYLGVTSMSAVLRVIFRLCPAAKEHTAQRAKAWNDVHYQSQLLPSLSLVSPGAGMNPLREQRCIDFYFDHIHPVTPILNEDDFRRNFASGTRLDGSWLALLNMVYTLGSIASGSDSLHVQYYRQARSFLDLDSLGSGNMESLQALCLLGGYYLHYRNSPNMAYAVLGAAHRVAIALGLHREPARSRAENVTEHDNYISRAETRRRTWWSLFCLDTWASMTLGRPTCGRWDSSTMDTLLPTPLFPDDHVAASLRASCLFCHICDRIQHRFAQPARLSAREAMAFDRELVEWHNSLPDFLKNPANSPPRLTEAREFMRNRYLNVRLILTRSFLLYLAHDHSLRRGANAISAVSGPSPEELALVETCRSVAMEAIDAITLYWTPNRIHVWNSAWYLFQACMVPILSIAIDAHVRNSARRQQHQQQQEQSQYPPPPSSTVPSQASHLGILQMPTAVTINSPEHNILLPSWCASLTKALELFNDMRSWMRDSDRTPDIVGALYEAVTTDLEGSGAGSAIRTPSTENSIDMSMWCDEQLVEMDWSAFLGGGGDSGSGGVDEMHNTNMFVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEF0</accession>
    <name>A0AAD8XEF0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364779.1">
        <property type="nucleotide sequence ID" value="XM_060508285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEF0"/>
    <dbReference type="GeneID" id="85392184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="207" mass="23504" checksum="064DB946D755B0C2" modified="2024-05-29" version="1">MNSTTHLTYLALVRIGNPDSHISLWPLHVRSSTDIRQPATSRPRQITFTMEDAVTHHHDLSQTSCTILPSRKGRDASVPPGRAVHSLPSRETTHQPLNQQPEPFELNLKFTAQSAPSRSTHNPPELNRGHDRLTHPLAKRCFQKKKKKSLHLGHSPDSFIRCCSIRSTMASAFVFSDVRNSHVQDIHQHYATRFLDLRGIVCYHMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFI9</accession>
    <name>A0AAD8XFI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_619592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365497.1">
        <property type="nucleotide sequence ID" value="XM_060508134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFI9"/>
    <dbReference type="GeneID" id="85392033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042276937" evidence="2">
        <location>
            <begin position="21"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="61" mass="6044" checksum="94F843C4A04DE583" modified="2024-05-29" version="1">MSNRVSNVLITWVLAAVAAADEPIPDTGSVGAGAIAGIVIGGVFVVALLAAAVGLARNRTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFP0</accession>
    <name>A0AAD8XFP0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361810.1">
        <property type="nucleotide sequence ID" value="XM_060510722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFP0"/>
    <dbReference type="GeneID" id="85394621"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="25817" checksum="CE468351E2706628" modified="2024-05-29" version="1">MRWWDKPPISAKLLRGSGPFGLLVLTNIARLSLRFDDIELLIASRLGSGLCELIVSAMTSQTRNKRGFLDALASFNKNILQTASVVIGHPSSGCRVPEWARVSPLVRLEMLNRHVDAPLLEHRQDFWDVALGDGSITYCTSPIVILLTKLRSEPLRARSSTRNVTEFWGHKQLVPHIRRLVPHIVRLCWAFTPRGRSIKNAKCEIRAWDDVRLRHAWESASRLGDARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFU7</accession>
    <name>A0AAD8XFU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_282966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365842.1">
        <property type="nucleotide sequence ID" value="XM_060502145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFU7"/>
    <dbReference type="GeneID" id="85386044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077523" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15379" checksum="B24EE2C3DB423CD9" modified="2024-05-29" version="1">MPFPLVFSCFFFFFPSSRVSRQPGPTMIDGLASAENPEKRECFGDFRNPFTSQLTLSVLKVIRGREGRSHGGWESHRSSVHLGRWIPARPGRLGRRASPLHSRENDKCPRAPVEKALIVKWDPGRLGSFAEDERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG65</accession>
    <name>A0AAD8XG65_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_252812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366789.1">
        <property type="nucleotide sequence ID" value="XM_060501940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG65"/>
    <dbReference type="GeneID" id="85385839"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042226613" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14224" checksum="10A016916FC9C194" modified="2024-05-29" version="1">MLCPTHTQHWHRPLLVLLWSCSLRILAAYDSLSQVTNLAPPSVHRLLSVRLCKRKSGQQTNAQSGAVPCICHLTPPKPDIPRRLVSSSLIHRLCADVQTPQCSALQTSTKLEYAELSSYQLSSGPSLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI14</accession>
    <name>A0AAD8XI14_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_624131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364135.1">
        <property type="nucleotide sequence ID" value="XM_060508426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI14"/>
    <dbReference type="GeneID" id="85392325"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="12">
        <location>
            <begin position="11"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="333"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1724080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="478" mass="52463" checksum="366A4F12EE8A7C4C" modified="2024-05-29" version="1">MTDTIPSLQAGPPDGERRCFICLMDENESGASESAWVDPCPCTLEGHQDCMIQWVTELEREGKEILCPVCKAKINIDEPYDPALALSNQIYKSFSRVSPGLILGGIGAGTWVSLAMYGNIAVRVFAGPEATYRFFFNDRNPRGVPMVNWIHVAILPTIAPALVLGSSVPILGNVFFMPVAALYGVFHMAKDDRFFTWPPSPQLAAACFPYIRAVYNNLWHEFVCPYEKRWERTIAGLPEPAPQANNRPNGNRRRRGRNNDGANAAARNVGLVGGLIDAAIDMLDIPDVEMEVELEEVEVGQDHDVVNLEILVEEIEEAHAAEQENGAGDIAAALPAQLPPPGNEPQQAPIVAPQQPAAQPAPAAPRQRGIQASLKDVTNAIVSTLLLPVFSAAMGEAIRLALPKHWTTPAGTFGRFKIRTGLLQEQWGRNLVGGCMYVVIRDVFRLYTKYRLAKNKPLRKIRNVDRRRSQTSSTSPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ5</accession>
    <name>A0AAD8XIZ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription factor MST12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_573392</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Transcription factor that may function downstream of PMK1 to regulate genes involved in infectious hyphae growth. Is not essential for vegetative growth, conidiation or appressorium formation. May be involved in the regulation of the expression of the cell surface sensor MSB2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the STE12 transcription factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366983.1">
        <property type="nucleotide sequence ID" value="XM_060504612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ5"/>
    <dbReference type="GeneID" id="85388511"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990526">
        <property type="term" value="C:Ste12p-Dig1p-Dig2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990527">
        <property type="term" value="C:Tec1p-Ste12p-Dig1p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000243">
        <property type="entry name" value="Probable transcription factor steA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000390">
        <property type="entry name" value="Transcription factor stea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003120">
        <property type="entry name" value="Ste12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052127">
        <property type="entry name" value="STE12_transcription_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427:SF1">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02200">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00424">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="573"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="603"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="404"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="416"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1726928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="712" mass="78582" checksum="B962F4F8B61E4C27" modified="2024-05-29" version="1">MYSQHAAAGMAPQKPETFMLSTEAQQALPHDAQVALQQVDNLKYFLISAPVDWQPDQYIRRFLLPTGEYVSCVLWNNLFHISGTDIVRCLSFRFQAFGRPVKNSKKFEEGIFSDLRNLKSGTDASLEEPKSPFLDFLYKNNCIRTQKKQKVFYWYSVPHDRLFLDALERDLKREKMGQEATTVAVSEPALSFQYDSSQSLYEQLTKAQQANSSSFNAQQVTFSQSQSTSPIMRPMDNMPPPQMIPQSVAPMQDGMESMVPYGAMGMPQQMPPQQMVKREPDFARVQYNQNGVPITQGHQRHASMPAYGLEYSPAPSFVSSQYEDYSNRGISFEPITPPQQALGMAAEPAYIANEETGLYTAIPDHMGGNVNGLNGMIQLPPSNLAGPQFSRAYGSNNVYSVIEGSPTYKQRRRRSSIPPSMSAIAAATAQAQAQAAAQQQQHQQHQQQHRPSDLRRSVSASVGPVAEGDESADNSPPGLAYSSSAMSMVSQQHKEMLDLSRHGTPLSTVEGSPALNPMSLQQQDYSHLQHDDMSGDGSMNGAPRPGMQGPNGVVRRARSATVMELGPYPQKSHSCPIPTCGRLFKRLEHLKRHVRTHTQERPYICPYCSKAFSRSDNLAQHKRTHDRGENGEAALNFSGEEEEEYSGEDQLGSLEEASPNSENAYVTASLNGVANGSTPPTSNGMAQSFNSLQTLSMPMTISQPAVNASAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ12</accession>
    <name>A0AAD8XJ12_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_117322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368726.1">
        <property type="nucleotide sequence ID" value="XM_060501131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ12"/>
    <dbReference type="GeneID" id="85385030"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079082" evidence="2">
        <location>
            <begin position="37"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="15072" checksum="77587DE5A1784637" modified="2024-05-29" version="1">MLKPCFFCPPSAIHLPSVPLWLAAVCLLAGSLAAAGQDSSHLLPPCLLLTPPLPYINILRICPGQGISSHPTQSTRQTRQTGGIQTHRTLGGFQDVCSRCLSVARVVEERDIESDGMPSFHFTPDSGPGSNTIEATQPSAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ91</accession>
    <name>A0AAD8XJ91_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_274493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366025.1">
        <property type="nucleotide sequence ID" value="XM_060502082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ91"/>
    <dbReference type="GeneID" id="85385981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042028189" description="Secreted protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9309" checksum="10C372A4C972705F" modified="2024-05-29" version="1">MVAYTTATSCRFLSVIALFFLLPTRQKSSGTIPPSGPRVAQHPFSPSTFDCQQSFLSRASVCSQSRQGSFRSQQEQTKRFGDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJI6</accession>
    <name>A0AAD8XJI6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_696357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366715.1">
        <property type="nucleotide sequence ID" value="XM_060511367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJI6"/>
    <dbReference type="GeneID" id="85395265"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167718" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="17"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="45"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="51562" checksum="FE84BA09342D2605" modified="2024-05-29" version="1">MYLAIALLVQVALALSAPLDDLTACLRTASVPIASSTPTPYNLRVPVKPLLVAVPTTNAQIASAVTCGSKSGVRVSAKSGGHSYISTGYGGEDGHLLINLDRMYSVTVASDGTAKVQAGARLGHVATELYNQGKRAISHGTCPAVGVSGHALHGGHGMVSHTYGLATDWIKAATVILANGTITRCSATERPNLFWSIRGAGSSMAIVAELEFNTFAAPEKVTYFDIDLVWDTVKLPQVLLDTQEFAKTMPAELTMSTTFNNDGSYLNGAYVGDDAGFRAAVQPLLAKIGAKVSSSKTFGWIDFIKHYAGVTDIDVTTATYNEHDNSYASSLTTPALTKTTFQSLVDAIAKNGLAPTRSWYMHMNFHGGSNSAVARPKTNDTAYVHRDKMLLFQLKDAVTTSQTYPSDGFALLQGLRQSITKRLSSDQWGMYANYPDSQISESEATRLYWGSNLNRLEWIKADYDPTDVFQFVQSIKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK38</accession>
    <name>A0AAD8XK38_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 2</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD2</name>
        <name evidence="16" type="ORF">BDZ83DRAFT_569848</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit. Interacts with pstB2. This interaction may be a means to structurally tether the donor membrane (ER) harboring PstB2 to acceptor membranes (Golgi/endosomes) harboring PSD2 during PtdSer transport to the site of PtdEtn synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endosome membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK38"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04039">
        <property type="entry name" value="C2_PSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04024">
        <property type="entry name" value="C2A_Synaptotagmin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000445">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000198">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000295">
        <property type="entry name" value="Phosphatidylserine decarboxylase proenzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00663">
        <property type="entry name" value="PS_decarb_PSD_B_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033179">
        <property type="entry name" value="PSD_type2_pro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5041755918" description="Phosphatidylserine decarboxylase 2 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041755917" description="Phosphatidylserine decarboxylase 2 alpha chain" evidence="12">
        <location>
            <begin position="1022"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="28"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="274"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="206"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="419"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="630"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1058"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="11"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1069"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1094"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1105"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="877"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="935"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="1022"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="1022"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="1021"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1728820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1119" mass="124658" checksum="C46D45D22B62BF20" modified="2024-05-29" version="1">MVRIIPGRLKSSSSLRNSRSSSPTRNNSTGSTNSKMELSPKENGLTLKVVVMKARNLAAKDRRGTSDPYLVLTLGDAKVTTHEVPKTLNPEWNVIEELPVNSTQSLLLDVICWDKDRFGKDYLGEFDLALEEIFANEQIEQAPKWYPLKSKRPGKKTSVVSGEVMLQFTLFDQSNTAASHEQIFEKLNTLLNQLPAGSRQITPTMTPLIQPVQNIRVSGTNPSPPLSRNQTDAYQEDDDDDDLDIEDDTPEDDDPSKPEVAEKRKRRLRIKGLKKKRRDQTYEFNNSGSDVVGVIYLEVLNITDLPPEPNSTRTTFDMDPFVVASLGKKTYRTKRVRHNLNPVFNEKMIFQVQGHEQTYSFSFTVMDHDKYSGNDFIADCSLSIRDLIDKAPKADPETGLYDVPEPHEYVAPQQRRFKKLGMSRTSSSQSLSKVRPGLSKNASSASTTTQTGTTTPTPPAQGSTLNPEFLSPEQALAGAGAQTAELEADDAEFHDFSVALKMKDAKKWEAKHNPVLYIRAKYVPYPALRQQFWRSMLKQYDTDESGRISKIELTTMLDTLGSTLRESTIDSFFQRFPHRAQGDDISDLTFDEAVICLEDQLEAKSRPQLSVTDRMKGMLPDADKVKNLLSTQGTSNVPSGPPAEGSSSSEGTLDVPELSTPGEEGELLDRDDLAEDRAGEEHVVEIRECPICHQPRLNKRKDTDIITHIATCASQDWRQVNNLVMGGFVTASQAQRKWYSKVITKISYGGYKLGANSANILVQDRITGQINEEKMSVYVRLGIRLLYKGLKSSNMETKRIRKMLKSMSVKQGKKFDDPASKAEIPKFIEFHRLDMSEVLLPTEEFKNFNEFFYRALKPEARPCSAPDRPDVVVSPADCRSVVFNSVNQATQVWIKGREFSIKRLLGDAYPEDVKRFENGALGIFRLAPQDYHRFHIPVDGVLGKPKTIAGEYYTVNPMAIRSALDVYGENVRVLCPIDSPTHGRVMVICVGAMMVGSTVITQKEGAQVNRADELGYFKFGGSTIVLLFEPGKMKFDDDLTDNSNGALETLVRVGMSVGHAPDQPQWGPDMRKDAKDVTDAEKKDAKRRIGGSLGSEESSSGEETPNASAGITTHAASAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKP8</accession>
    <name>A0AAD8XKP8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_748575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369179.1">
        <property type="nucleotide sequence ID" value="XM_060513633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKP8"/>
    <dbReference type="GeneID" id="85397531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="67" mass="7560" checksum="8EA8B184B2CEA3F2" modified="2024-05-29" version="1">MAVNKDTGNRKTASTLLKPRGRPAKSSTENALVLRMEGPDSLMKMLEIPLLMNLQLQDSLLREHQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL00</accession>
    <name>A0AAD8XL00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_568607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369376.1">
        <property type="nucleotide sequence ID" value="XM_060504092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL00"/>
    <dbReference type="GeneID" id="85387991"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844">
        <property type="entry name" value="SER/THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37844:SF2">
        <property type="entry name" value="SER_THR PROTEIN PHOSPHATASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_1G14840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="266" mass="30036" checksum="6BE14830DA6011FD" modified="2024-05-29" version="1">MAIQIVSDLHLESPRAYDIFEIVPQAPYLGLLGDIGNVAAHKEECLAFLTQQLRQFRAVLFVPGNHEAYHSSWGITLKILQDFEAAAKKDSSLGDFVLLDRSMFRVPDSNVVILGCSLFSLIPPESADSVSMGLQDFFQIDDWEISSHNEAHKRDLSWLNSQVAELEKSEVRIIIFSHWSPTRDARASDPRHSQSPINSGFATDLSKEDCFKSARVKIWAFGHTHYNCDFSVEREGDTEPLRLIANQRGYYFAQAAGFEENKVIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH6</accession>
    <name>A0AAD8XLH6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369653.1">
        <property type="nucleotide sequence ID" value="XM_060510098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH6"/>
    <dbReference type="GeneID" id="85393997"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="149"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="375" mass="42196" checksum="14E08D43850A7EE9" modified="2024-05-29" version="1" fragment="single">MLPCSSSISRFKQIINHSNQKGIRDEHLQENSRDILKESSVEDAGPSLMLISEAVQQLVALGGLRCVVSKCQVSTKRTGNPQSKKHPNEEQHQATTALITSAEFSWEGRFRRPTAVCAIWFTKFARQPEEVQEQASGSNGEPGDVLSIQYCEAAHIYPFASIKKSGTIVTSVHALIKVFGRGTAQRFTDALRMVDLDSTVNLICLDHIPRRMFNDGRLALQPINRGTQSNGDHFIRLRVHLLQTQARQYELRAWRSDLAQDPYELLENFQLGDDEPQKPRLVSSVTQRGISDGHKFDITAKTQEDLPNWDLELRYRISVMNHLISAAGVSNEEAGESDEEVSDEEFEDIDVVEGAIRNLEEIAKQRLEEADEDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMB7</accession>
    <name>A0AAD8XMB7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_567105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370140.1">
        <property type="nucleotide sequence ID" value="XM_060503922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMB7"/>
    <dbReference type="GeneID" id="85387821"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205">
        <property type="entry name" value="NB-ARC AND TPR DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35205:SF1">
        <property type="entry name" value="ZU5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="25723" checksum="F1C4109907C72FEE" modified="2024-05-29" version="1" fragment="single">MARFLPKYGNGSILVMTRNKEAGSRLVPGQPLLEVGPMSDGESVQMIREITGDSSLSMDAFTVLSNRLENLPLAIAQAAAFMHENCMSLDKYLDILNKSNSVEVQLLGGNFEAVGRDADVPHAVTATWVVSFEHIKEKNPLAADILSMMAFFDRQAIQRQFITIYMYLERDGAYSILLEQALGILKAFSFIKENKDGTLCMHRLVQLATADWLKRKGSARRFFGRALETLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XME0</accession>
    <name>A0AAD8XME0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vps54-like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_747999</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370049.1">
        <property type="nucleotide sequence ID" value="XM_060513548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XME0"/>
    <dbReference type="GeneID" id="85397446"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="845"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="811"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1096"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="329"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1111"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1124"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1152" mass="125613" checksum="AAE45B69A1E628DC" modified="2024-05-29" version="1">MYSSPGARKSMDTISSMSPPATRTEFPFHKLVTLPGPSVATVALTAARQGQAHTYHTTRRGSNASSIHSIGGSLDTSSSTWANAVLESGQNAISTLLQPPIVRTGLQPHTSAPASSAHKPPTARDIPPVTLTNIPHIDPAEFKPYLSQVGALYEQLRRVKEQDDDRPGSSGRRSSKHDEFGDSVDESHLKPAGRQPSRRKSSIASITSISSLEGPGLLRRSSSGYSRKGAHGPPPLSTIPNVYFDDDFHLENPRTFDVVSERSEVVPPAPGSVDSKNDGNGNIVAPRKALATNAILQEKLSWYMDTIEIHLINSISTASTTFFTALGSLRELHSEASESVDRIKALRKELEALDEEIATKGLNIVQKRRRRENVQALNDAVLQLKHIVEGVASCEALVDAGEVDKALSNIDTLELLIAGEHDDSPEAEPPVLPLARMRDLRAATALQSVNDDLQQLRSRIGKAYETKFQSLLLADLRRHVESVQSREVLLRWGSSSLRARGGASRESAGPPAYLASTQELRKAIMPNLHGLHRAHHISAAIAAYREIVLREIKNLIRRPLPSSNDDDNESMMSASTMSGGKHLSNQEKSSILSRNLRALDPKDAEDLLNSIYIGVTETLRRLTTQVKVLLDIASCLTEEATAAGLKSPPIRSPLASPTPFDREFPRFDESPSFEVQEEIHKAMDIANLVGQAVDVAQDKIVRVLKVRSEQSTHLSLSWFLRYFTLNLFFANECEALSGRSGTALKTLVNGHIKEFVQQHGDAEKQKLAQGMESDQWSAKDFDEKNKALLDQVLESSTKDAAVWSEGTKIWEENPDDVSNGSAAPPPETNGTSGKEKARVAEIESETFLLPNSAILGLEGISHFMHLIGSIPSMATDVASSLIGYLQLFNSRCTQLILGAGATRSAGLKNITTRHLALASQALSFIATLIPHIREFVRRHAGSGASVSSLMGEFDKVRRLFQEHQNSIYDKLVEIMSGRAAQHSKSMRAIDWDHDGSQSTHPYMETLAKETTTLHRVLTKHLPETSVQLIMRPVFSSYKDQFGRVFEVADPKTAIGRDSMLRDVDFFITKLGKLDGFGDAGEYLKSFINAKEIKSAVASPPPEKQAAADGGSETTVSARNSTAEPESRQSADDSGKTESPPSGAGEEETKQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNC3</accession>
    <name>A0AAD8XNC3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_373580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370574.1">
        <property type="nucleotide sequence ID" value="XM_060502659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNC3"/>
    <dbReference type="GeneID" id="85386558"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032506">
        <property type="term" value="P:cytokinetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000678">
        <property type="entry name" value="Rho GTPase Rho4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="249"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="31533" checksum="0E10E95C8240328C" modified="2024-05-29" version="1">MASSYQYRNSYHNSSQNISEKYDDGRPATSRRNTRLRSSDGTVSTTMSSSTGRESAATHVTEGPAYSKKIVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITYPTHPPSGKTVELALWDTAGQEEYDRLRPLSYPETDLIFVCFAIDCPNSLENVMDKWYPEVLHFCPYTPLVLVGLKSDLRFKKTCIDMLKTQGLTPVTQEQGRAVARKMGAQYVECSSKEMTGVDEIFEQAILTVVANDRKNQEAQAAASPSTPSGPPGSSAGFPGVALKKKKKRNCKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNN6</accession>
    <name>A0AAD8XNN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcipressin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_566550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RCAN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370674.1">
        <property type="nucleotide sequence ID" value="XM_060503859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNN6"/>
    <dbReference type="GeneID" id="85387758"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008597">
        <property type="term" value="F:calcium-dependent protein serine/threonine phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12434">
        <property type="entry name" value="RRM_RCAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000503">
        <property type="entry name" value="Calcineurin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006931">
        <property type="entry name" value="Calcipressin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300">
        <property type="entry name" value="CALCIPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10300:SF14">
        <property type="entry name" value="PROTEIN SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04847">
        <property type="entry name" value="Calcipressin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="27934" checksum="D47C8FBBF8687BD0" modified="2024-05-29" version="1">MESPQLDTRPIFSRRSTGSNKSLSLDLSSLPPLVQPTPPTNTLLFTNLNDTSIFRPDNLQTIRDLILKTAPVHSWAPLKSFRRIVVSFFSEDDAIAVRRVWDGEAVMGERVRVYFGQPTPVEVTDRHLALPDAGKLFFISPPPSPPHGWEMKLEDAPNKMVHAEDLADALAKLHHRPTGVETPISPVDGSRQTRSRSSTLLYQPDANGTSPDLPAICLEDMTDEPMEFSPIEPKPIMAHTSRPPVELMHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP07</accession>
    <name>A0AAD8XP07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-ubiquinone oxidoreductase 12 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_600727</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370867.1">
        <property type="nucleotide sequence ID" value="XM_060507052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP07"/>
    <dbReference type="GeneID" id="85390951"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1730812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="101" mass="11646" checksum="7990DB477C15358D" modified="2024-05-29" version="1">MPTPESAMFLAQKPKVPPTFDGVDYDDTKAFKQAQDAIIREQWVGAMMLRLVGEELGKCYKKEGVNHLENCGHLREKYLQLLKEKKVKGTLFEQQNYISKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP18</accession>
    <name>A0AAD8XP18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_600799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_060507055.1"/>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="166"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
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        <location>
            <begin position="381"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="66368" checksum="CFC11A52FF5B431C" modified="2024-05-29" version="1">MSRASLGKRTRSVQDQDLVDLPAKRTRRRTRAASENDENADPEVTATTPDVDNDLDDTYVEPAAKKLRRSPSQSFLKSIPITPQTPRHRDVFANSPSTPRQVVKSAGKLFQRLTPQSPLTPGSLQTVYHSARQLFARGADPGELVGREKEREQLTQFVQRCSSTTPNGCLYVSGPPGTGKSAMVKEITEKSTEPTVVRQAYVNCMSVKSSKDLYNTLLELLGHESDLPEALAMEELQKIFVTKKKGSPVYLLVLDEIDHILTMGLESLYRLFEWSLQQPSRLVLIGIANALDLTDRFLPRLKSKNLKPNLLPFHPYSAAQIKSIISTRLMTLLPTDSSNKTLPFFHPAAIELCSRKVSSQTGDLRKAFEICRRALDVVESETRRQHENEAREKVLQMTPSRKPLGENANMAGSSGSSRSVSHVAATSLKSLTAESAPRVLLKHLNQVTQAAFSNGTNQRLKALNLQQKAALCSLVALEKRNRALRMTTGPSTPTKSQTMAPTVKTLYETYSILCTRDSVLHPLSSSEFREVIGSLETLGLVNPVDGKTGGLVMTQTPSKRGRKAALPTGEDKRVASCVGEKEMENIAEGVGAGILSSILSGEALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP30</accession>
    <name>A0AAD8XP30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_295078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371100.1">
        <property type="nucleotide sequence ID" value="XM_060502212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP30"/>
    <dbReference type="GeneID" id="85386111"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042147095" evidence="2">
        <location>
            <begin position="18"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="252" mass="24236" checksum="9E88F314D981C5D4" modified="2024-05-29" version="1">MKTSATLILAASALASAQVTYNATTGQYICSRPNSAFCAGDSFGTDIIIRCDANGRGQPGRCTNNLAGQFPLGVNPSLCWMSQPYSGDAACEKNCVVYASPSPFQLPPSVCTPYASGTGTGTGYVPRPTYPIGPPPRSSGNGTMTSTAGPSRPTGTGGGGGTGGGPAPSGNGTAPTSRGGGGGGGGNGGGGGGGGSSGRPTTATSSSIPSGTRTPIPPSGTITNPTSVPTAAAVHNSVGSLVVAGIVAAYFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQK7</accession>
    <name>A0AAD8XQK7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_746189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371828.1">
        <property type="nucleotide sequence ID" value="XM_060513225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQK7"/>
    <dbReference type="GeneID" id="85397123"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8809" checksum="93021836BDC9A31E" modified="2024-05-29" version="1">MIIPVRCFSCGKVTGDLWERYLKLIDDGITDGDAMDQLGLKRYCCRRMVMTHVDLIEKLLKYTPDGRNEKKMSLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0I3</accession>
    <name>A0AAD9D0I3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_647552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370053.1">
        <property type="nucleotide sequence ID" value="XM_060510097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0I3"/>
    <dbReference type="GeneID" id="85393996"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="557" mass="56011" checksum="0E583B66D4FA0628" modified="2024-05-29" version="1">MTKSLRGSSLPQARSYHHNHYHLHNQRAATPENANHHHRQLDDPSPTTPSPDAATSSSAAAPRIVVQTVSLIQIVDATGSPIQVQTIFPTAATVDASSTTSAALDLSIAAVPSSTSSTDSSTTSSSTTNDSALSTPAPTTSSSTDSSTSQDISLTSDPLSTPAPSEAAPSLYPTLSGQSNSTIFACPRPKQLTQYLAFLTSTNSSSTSVSTTTSLTSQLSSGTTSVTSSILSSLLSTTWGSNSGSTATSTSASISTSGSSRLSTSTFTTSASQSSSNEATASGDGTAGGIGGGAAGTAAPTSTSTSDDSSGSGSPTPTGTVVGSVVGSLAGAAFLVVLVFLALRWKKRTGGRFRLSEASAGKRGILTGSGGPPGGNSGGMVQRSLSFDPTTAAAGAGAGAGAMAVAHKPSSRRASEPSETGERGFVRVAGRKLPSVLQAGGDGYTDPREGTSAAVNDDESVYFRDSQAFFDPNGQTTRLALGSPMRPVSGVVVFKESPARTPVTESAPFPPPAASPQSNPPFVPLQPPGRDPIGRTLPSQDGSRGSRGSASRFHEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0J0</accession>
    <name>A0AAD9D0J0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_716043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369932.1">
        <property type="nucleotide sequence ID" value="XM_060511811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0J0"/>
    <dbReference type="GeneID" id="85395709"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="190"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="303" mass="35103" checksum="E56692CF7DF5A37B" modified="2024-05-29" version="1">MLSGKRKQGFSGLQRRVKPRREAEPEVDEQISSEPEEMGIDGDELSEDEEDENMDEDDEESDASPPPKKSNIDISSVSFGALAKAQASMPSAKRRKRGASPSEDSDSDSDSGPEEVGRKSKHGADHVKRSSKHAPMEQSSKKPVSRRREIIAVPKMEVRDPRFDPMSGPVDESKARRAYAFLDDYRKDEMKQLRAEIKKTKDADKKEEIKRMLLSMESKMKARERKQRADDVIQEHKRKEKELVKEGKQPFYLKKSEQKKRFLMDQFAGMKKKQVDRTIERKRKKVVGRERKELDKMQRRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D244</accession>
    <name>A0AAD9D244_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_566540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370549.1">
        <property type="nucleotide sequence ID" value="XM_060503857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D244"/>
    <dbReference type="GeneID" id="85387756"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041770976" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="30"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="490" mass="52422" checksum="C565A52A6D653ACA" modified="2024-05-29" version="1">MKHATLIIGLLCGLVVAKPTNFKTWSVGQAVFTTSGRVIGHAAQDVPDVSEYLGIPFAAAPVGALRFQPPVPYDGSAVINGSAFGPGCMQPSDTEYPQSEDCLSVNVWTKPQVGERKKSVLVWVHGGAYSYGSAREDGYSGRFFANDSDVVLMSINYRLGIFGFPGNPATTANLGLLDMRLAMEWIRDNAQKFGGDPSRISVFGQSAGAGMADFYAYAYASDPIANGFVLQSATVVGFPALSRNYTSTRWFRLAAVVGCGTGTSNYTDPKLVTDCMKNRTTEQIFGAFGPEETGVGSTPAFGPGVDDILVFEDYTDRRAAEAGYLIGDNANEAGLFRSMQPNRSDAYWNDFNFRYYTCGDAIRISQAVNDGMSAWRYRYFGDFPNLAISNNPASGAYHGAELPPLFGTLPQTPPSTSVELATAEFLRGAWTTFAKDTSSGLLGYAGGWPIYDPSQPTLAQIASDNQTGINLGFGNSFDGICSSLPAIPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2F5</accession>
    <name>A0AAD9D2F5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_600242</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370745.1">
        <property type="nucleotide sequence ID" value="XM_060507024.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85390923"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000393">
        <property type="term" value="P:spliceosomal conformational changes to generate catalytic conformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18019">
        <property type="entry name" value="DEXHc_Brr2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000005">
        <property type="entry name" value="Pre-mRNA splicing helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000133">
        <property type="entry name" value="Pre-mRNA splicing helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000368">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000254">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000013">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="536"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="755"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="1387"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="197"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2205" mass="249582" checksum="A386991FEE331E02" modified="2024-05-29" version="1">MSNQDQHRDVSQYKYSAMSNLVLQADRRFVSRRNDEATGDPESLAGKLSIRDMGARVAREIAPKQKKSTGLTGVERGSLQEGEDVLAREQKKKKGEKAQPRGAGVLGTGDLFVEGIRYRPRTPATRATFELILKIVSDNLGDVPQTAVISAADVTLEFLKDDDLKDTEKKREIDDLLGVSMSAKEFNELVNLGKKVTDYDAQDEDEDMDDNAEDADGAELDERQGVAVVFEDSDDEEGGIVNEVREESSEDEEADEDEDEPAADANDAMDMEDDAMVIDSAPRKKAQESKQAKSVSARDIDAFWLQRQIGKLYADSHEQHDKTTDALRILSGEPDEQGGEDKSLREIENDLMELFDYEHHELVQLLIGNREKVVWLTRHSRAETDEERAVLEREMASEGLQWILNEKFGKKGDDQKGRKMEIKMDLDAPSSLTNAPPAEDERPQGLVGGLQPRKLINLENLVFDQGNHLMSNPKVRLPEGSTKRTFKGYEEIHVPPPKKRSDASDTLVPITEMPEWSRLPFGTTKSLNKIQSKCYPTAFGDDGNMLICAPTGSGKTNVAMLTILREIGKNRNPETGDIELDNFKIVYIAPLKALVQEQVGNFGKRLEPYGVKVSELTGDRQLTKAQIAETQIIVTTPEKWDVITRKATDLSYTNLVRLVIIDEIHLLHDDRGPVLESIVSRTIRKTEQTGEPVRLVGLSATLPNYKDVASFLRVDISTGLFHFDGSFRPCPLRQEFIGVTDRKAIKQLKTMNDVTYNKVIEHVGAKGNQMLIFVHSRKETAKTARYIRDKALEMDTINQILRHDAGSREVLNEAASQATDKDLKDILPYGFGIHHAGMNRIDRTDVEDLFARGAIQVLVCTATLAWGVNLPAHTVIIKGTSVYSPEKGSWVELSPQDVLQMLGRAGRPQYDTYGEGIIITTQNEIQYYLSLLNQQLPIESQFVSKLVDNLNAEIVLGNVRSRDEGVEWLGYTYLFVRMLRSPGLYQVGAEYEDDEALEQKRVDLIHSAASVLRKSNLIKYDEKTGKLQSTELGRIASHYYITHGSMETYNNLIQPSITTIELFRVFSLSAEFKYIPVRQDEKLELAKLLGRVPIPVKESIEEPHAKINVLLQAYISRLKLDGLALMADMVYVTQSAGRILRAIFEITMKKGWASVAKTALDLCKMAEKRMWPTMSPLRQFPNCPRDIVQKSERIEVSWSNYFDLDPPRMGELLGMPKAGRTVCGLVAKFPRVEVQAQVQPLTRSMLRVELSIAPNFEWDVEIHGPAESFWIFVEDCDGEDILFSDQFLLRKEYAESESNEHIVDFTVPITEPMPPNYFISVVSDRWMHSETRLPVSFHKLILPERFPPPTELLELQPLPVAALKAKEYTKLYPDWDHFNRIQTQTFNSLYNTDQNVFVGAPTGSGKTVCAEFSLLRHWSKADAGRAVYIAPFQELVDSRLDDWQKRLGGLRGGKTIEKLTGETTTDLKILERSDLILATPIQWDVLSRQWKRRKNVSTVELFIADEVHLLGNNMGYVYEIIISRMHYIRTQTELPMRIIALGVSLANARDLGEWIDAKKHDIYNFSPHVRPVPLELHIQSYTNPHFPSLMLSMAKPTYLAITQMSADKPAIVFVPSRKQTRATTRDLLTAAFMDDDEDRFLHAEVEQMRPLLDRISEEALAESLSHGVGYYHEALSQSDKRIVKHLYEHGAIQVLVASRDVCWELNSTAHLVIVMGTQYFEGREHRYVDYSLSEVLHMFGKALRPSKDGRGRGVLMLPSAKREFYKKFLNEALPVESHLHNYLHDAFVTEISTKMIESGDDAINWTTFTYFYRRLLANPSFYSLTSTTQDGLSDYMSDLIQTTLQELSDSKIIELDEDDGSVAPQNAAMIAAYYNISYITMQTFLLSLSAKTKLKGVLEIITSATEFEAIQIRRHEEGILRRIYDRIPVKMAEPVYDSAHFKAFVLLQAHFSRMQLPIDLAKDQEVIISKVLSLLSATVDILSSDGHINAMNAMEMSQMVVQAMWDRDSPLKQIPHFTPEVLKAANEFGVKDIFDFMEAMNPEENPDYAKLVKRLGLSQKQLGEAAAFTNDKYPDIELEHSVLDEDDIRANEPAYLSVQIQRQVEEDEEFDPTVHAPFYPAKKLENWWLVVGEQTTKNLLAIKRVTIGRELKVKVEFTVPTAGKHDLKLFLMSDSYVGVDQEREFSITAAEGMDVDDSDEEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3I5</accession>
    <name>A0AAD9D3I5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal calcium binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_746160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371795.1">
        <property type="nucleotide sequence ID" value="XM_060513219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3I5"/>
    <dbReference type="GeneID" id="85397117"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022013">
        <property type="entry name" value="CBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12192">
        <property type="entry name" value="CBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918605" description="Fungal calcium binding protein domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal calcium binding protein" evidence="2">
        <location>
            <begin position="58"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="116" mass="12014" checksum="1A6C1CBA7A90EA5C" modified="2024-05-29" version="1">MQFNINTVALLAAALLPLASAVPSDANAVEATLAKRQRQYQCETSNNLGACNNAIAKLRGHEARGCDVWSCIGAFAAVIPACGAAVDEFFLNPLADVACLGAVANFQGPCKGCEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4L5</accession>
    <name>A0AAD8U4L5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000283">
        <property type="protein sequence ID" value="KAK1703431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357287.1">
        <property type="nucleotide sequence ID" value="XM_060509791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4L5"/>
    <dbReference type="GeneID" id="85393690"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053018">
        <property type="entry name" value="Elsinochrome_Biosynth-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37577:SF1">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="49443" checksum="BB21E88C1FEF319B" modified="2024-05-29" version="1">MTFEVYLYFQVYCLGGRNTSQWTIMGASISIAQCKSHYNTTVDCSVTPDGSGGFQTIAGYGRGEVPPEPDIAGIGIVSVFIAVASFAFAIGVFDVTWTMVKHCSRKHQRIKTSGFQRPRWASKFSRSKFFQALVISCSDQQVFTGGAYLVTIRFWAGCSITAYHYNIVANMLLITCATHLMSVVISKNYFERFFLACLRVCFITAVFAMTGLLLSNQNASNDLPFPTKVPPSNETESLLFYHAVCFQTGEDSIEQLKHLLLDSVRNGTAAEKALFQSTPGNYIQGWNLYLVILIWYGVSILAELGRCCYRSRRKHREAAENNGWRKHDNYFIKIFSGVGKISYGVYLIGGIGICGTTVVMSSLYIMSLRRWVKTSRWLELKEGGQSEEDDATSFGQLVPIILVGLTAFTFLSILSEMCAEGRKSCQTKDGYSSVTQHRKGSGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7K9</accession>
    <name>A0AAD8U7K9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyoverdine/dityrosine biosynthesis protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_594749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000254">
        <property type="protein sequence ID" value="KAK1704899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357509.1">
        <property type="nucleotide sequence ID" value="XM_060506731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7K9"/>
    <dbReference type="GeneID" id="85390630"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007817">
        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285:SF5">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05141">
        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1704899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="336" mass="38629" checksum="8D1A46735277CCBD" modified="2024-05-29" version="1">MIWKRNKTDETSARILAIIFEYALDKFDNSKDLHAAGMTKFLSVINGFVTADKPIDMCLPAFPFKSANKADKVLGSLPDKAEELALQRLNAICLRIRDIYSPGARITIISDGLVYNDLLCIPDRDTWAYGEALRAIAVKQSFNRINFSCLKELLEFPLSERMSEIVYIANATNLRRYLLNKYGKEDLDINYEIATQPDTLMTYCGYRRFLESDLQHIFPTGKNRSHNSYKRDIKYLAREMMIRGYAFAGAIKAAFPNHLRLSIHHSTGEHKVSLSLLHTETGYTTPWHCCVALMANGEWLSAPISTFKDDPYFDVIFEDGRPSYFREKLYRDEDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U850</accession>
    <name>A0AAD8U850_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_108184</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000154">
        <property type="protein sequence ID" value="KAK1711912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359236.1">
        <property type="nucleotide sequence ID" value="XM_060501068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U850"/>
    <dbReference type="GeneID" id="85384968"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000171">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01740)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="72"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1711912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="527" mass="56785" checksum="7B61ED15E42CAA97" modified="2024-05-29" version="1">MGTDTDPTRKLDTAQKIDSHAGVAHDGSIDIHGIDDAAIIPKGALDPVYEAKARVLNRAIQDIGMGWYQWQLFIVVGFGWASDNLWPIVTSLIFTPITNEFGPSRPPLLTLSQNIGLLAGAMFWGFGCDLFGRKVAFNLTLGLTALWGMAAAGAPSFAGIGIFAAFWSFGVGGNLPVDSAIFLEFLPGTHQYLLTVLSIDWAIAQVIATLIAWPLLGNLTCQEGATCTKANNMGWRYFLITIGGLTLIMFLIRFVLFTIYESPKYLMGKGRDEDAVRIVHKVARRNGKLTSLSIEDLKACEPEGYVARTDAATAVKRNLEKLDLSRIRVLFSTRRLALSTGTIMAIWALIGLGYPLYNAFIPYIQATRGAELGDGSTYLTYRNSLIIAVLGVPGALLGGWLVELPALGRKGTLAISTVATGVFLYCSTTAMTSNALLGWNCAFNFCSNVMYAVLYGFTPELFPTPQRGTGNALTATCNRIFGIMAPIVAMFANLKTSAPVYTSGALFIAAGLLVLILPFESRGKAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8K9</accession>
    <name>A0AAD8U8K9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multidrug resistance protein fnx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_723591</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359476.1">
        <property type="nucleotide sequence ID" value="XM_060512579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8K9"/>
    <dbReference type="GeneID" id="85396477"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="60"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1712619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="50549" checksum="4855D81929A0EC06" modified="2024-05-29" version="1">MAAPNEKTSGILTEAASAPVVGQLTAGPSPELANSSEDEKPTHEFNEQTNYVRPRTIITIFLACASVDLVALMDQTTLAASLNIIGNSLNASNQTAWIASGYFITSTVGQLLYGRLSDIWSRKVILLIGLAIFFTGSLASSVSNTGTQLIVFRAWTGIGGGGLMTVAQMIVSDVVPLRERGKYQGILGSVVAIANGIGPVIGGALASQSKDSWRWIFRLNMPLTLLCTLCVIFFMPLRKVEGNWKLKLKAVDFVGSFLALAGTTVLMLGLTWGGGDHPWNSAHVIATLIVGFFVCVGFILWQWKGAKFPLVPLHIFKSKIVNGACITMAINGWNFVVQVYYIPAFYQLAYGYSATKSGAMLLPVTLTQTLFSTLAGLVVHKVGRYRECILLGWVMWAVGIGLMSTLDEFSSVGNQVGYSLLVGAGVGNTLQPALIAIQAGVSRRDMAVVTSFRNFIRNFGSTIGLAISGTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8T8</accession>
    <name>A0AAD8U8T8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_767445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358487.1">
        <property type="nucleotide sequence ID" value="XM_060515286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8T8"/>
    <dbReference type="GeneID" id="85399184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF129">
        <property type="entry name" value="FLAVIN OXIDOREDUCTASE HXNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1709148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="410" mass="44956" checksum="849686427EE8B839" modified="2024-05-29" version="1">MPKATTPPPAFAALKDTVLFTPLKLGGISLKHRIVQAPTTRMRSEFESRGVHVPGARVAKYYGERASAGGLQITEATDICLNASAYPGVAGVFTDSQLQGWRKVTDAVHSKGGFIFVQLWHTGRASSAGMRGGETPISSGTQPMDGNYLDGTACKDGPPRPMTIEEIHGLTAEWAAASKRAVEVAGFDGVEIHGANGYLLEQFLHDNINTRTDEYGGSIENRSKFLFEVLSAVSAAIGPEKVGVRLSPYNYFQGTRDSNPNKHWSFISQKIAEMTETERPAYVHMIEPRFDEVLDEEQKLASLSGIKSEATQTNNLTQFRDILKPAGVHFFAAGNFNRDNAVTKLKSGEADAIVFGRYFIANPDLVERLKNGWELNPYDRTTFYGAEPPEKGYNDYEFYKVDNAKVTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8X4</accession>
    <name>A0AAD8U8X4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TLC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_684567</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000199">
        <property type="protein sequence ID" value="KAK1708196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358228.1">
        <property type="nucleotide sequence ID" value="XM_060511241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8X4"/>
    <dbReference type="GeneID" id="85395140"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="135"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1708196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="52220" checksum="26BA9DC9E9C9C6DE" modified="2024-05-29" version="1">MIEPTTKIAHTERASPVASMAPRLGHSQKLKIIDSSRRKKFVQWLFDNQTHLAFHTTAPLLLTHICIPAARPYTSKFIKLSYYNTTTGKYGAGHDDLYFVAFCVVLLIGIRAALMRHVLEPLGRHWGISKKKDVARFSEQGSMLTYYSVLWPVGMYLYCKAPYYLNMKELWNNWPQRELDGLMKGYIMVQWAYWVQQVISVNIEARRKDYWEMIVHHAITISLIAACYAYHQTRVGHLILVLMDVIELIFPLAKCLKYIGFTTLCDVIFGVFLLVWVWTRHVFYLMTCWSVYYDLPRSLKEPCFRGAPSDIEGPFSAPKEGWSHLLEPFKDPAGTVCFTNGIRYGFLTFLLALELVICAWSFFIIRVSVRVLKGAPAEDVRSDVDDEEEEEEKIEYEEIEAIEEDVGVESIDLKAWDRSSSRKEPSSSRVSGVRTHSGRKELLNRIGCEKQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U982</accession>
    <name>A0AAD8U982_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_78093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359821.1">
        <property type="nucleotide sequence ID" value="XM_060515536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U982"/>
    <dbReference type="GeneID" id="85399434"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42032:SF1">
        <property type="entry name" value="YALI0E30679P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1713768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="504" mass="55282" checksum="697E7453CF3A5519" modified="2024-05-29" version="1">MSDENSSRSPTSPLTTTSNTSRKQTISSPGTTASPAPSGHAFKRAVTVDETSQVRRRPPFSHIPTENSFAERGLGRRRSSTLSDYSFGDARDFLNPRPGDGIPSTSTDELSSWASVPLAFALLPAVGGLLFKNGSAVVTDVMLLGLSAVFLHWSVTHPWNWYHSAQAVRERAEISTSAVIDDESETEQGAGSPSPAASTANGHTTNGSVDEASEVPTTPTSLVQEQVRKTTTPPRNKKEDALAELWVHEILALISCFMFPMLGAYLLHAIRAQLSRPSEGLVSNYNLTIFLLAAEVRPISHLMKLVQCRTIQLQRDVHVNPYKDDGATSDQMRVLMARLEMLESRPEPTPMKHNGNSDNSKIKQEAAIARDVRNAIQPDLDALNRAVRRYEKKATVLAFQTESRFAAVDTRLNDAIALAAAAAKNSVARPGFMQWLVESVWAIITMPFFAMVALLVLPFKTIRGLLKRKKKSLPERTSKSSRNGKTMGHGRMTADRQPSRVSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9M1</accession>
    <name>A0AAD8U9M1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_594701</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000251">
        <property type="protein sequence ID" value="KAK1705030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357532.1">
        <property type="nucleotide sequence ID" value="XM_060506726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9M1"/>
    <dbReference type="GeneID" id="85390625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF84">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09170)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="51"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1705030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="476" mass="52698" checksum="9FFAA9BC7B75D78A" modified="2024-05-29" version="1">MVKDQEAVVDHIDHQESSKGGVFQSHPDKFGSAAKVDPKEIALVRKLDTYLMPILWLMYFLNFLDRNAIVNGKLNNLDNDLNMKGSEYNTCVSVFFVGYITGQVPSNMLVTRVKPAYYMSGWMMAWAIVSTLICVVKDYHGMLALVLGLTEAPFYSGACYLVSLFYTRKEVATRLAVFYTGNLLASSFSGLIAAGVFAGLDGRHGMAGWRWLFLIQGVVTIGVAVVAFFVLPNAPLQTRWLTQEEREMAHSRVAKDTTEKRQGTSIWSGLWDAVTDYRTWVFALMGNLHLSANNFKNYLPTAVKSLGFSTTTTLVLTCPPYLIGGATSVLVSWSSGRFNERTWHITGSKAVAIVGFAVATSTIHIGARYFAMVLFVAATYGVNNINVAWTSATVGQTDEKKAAAIAIVNTFGNLSFVYTPYLWPDSDSPLFRRAMVASITFSLGVVLTAWTMKFVLKRANREIRSTQDESINLYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9V0</accession>
    <name>A0AAD8U9V0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="10">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_643395</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357915.1">
        <property type="nucleotide sequence ID" value="XM_060509670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9V0"/>
    <dbReference type="GeneID" id="85393569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF101">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="51"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1706787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="296" mass="32243" checksum="0A68E20FED4EE0D7" modified="2024-05-29" version="1">MASVTLRRVRPATIAATVAAGGIGLAAYSRLFVNSASAESGAPPRVFGAGPAFVSLALESSEDVNHNTRRLRFKLPQREAVSGLSLTSAVLTMSWPEGRWLPVARPYTPVQPLDDTGYLELMVKKYPDGKQSTHIHSLTPGQKLLFALAIKGHQWKPNSYSHITLIAGGAGITPIYQLAQGILRNPEDKTAITLVFGVNSDQDVLLKQEFEQFEKEFPGRFKAVYTVSNPVANSPYQKGYVTKQLLEEVGVAPQKEEDTKVFVCGPPAMEAALVGKRSAPGVLQQLGYRKDQIHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA45</accession>
    <name>A0AAD8UA45_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metalloprotease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_594054</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Secreted metalloproteinase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357724.1">
        <property type="nucleotide sequence ID" value="XM_060506689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA45"/>
    <dbReference type="GeneID" id="85390588"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="11">
        <location>
            <begin position="169"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1705945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="25683" checksum="5FB5C2EA0AE489F5" modified="2024-05-29" version="1" fragment="single">LSASLAQASLHSPTSFCGTPDPSDHQIARSLAGRDVSSGSSLLAANISVPVYLHSIAPNETALLSQATLEAQFQVLHDTFSKYGITMTLGGTSRTVNASWSTVTNPTDELAMKSALRKGTYQSLNIYVQAIHPTLGRCFYPEADAFPGSETFILDGCQIDANTVPGADSPTGNDRGYMAVHEVGHWFGLPHTFQGGCTGTDYVDDTPAQATPSWNCTLGQDTCPDLPGVDPLYNFMNYQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA52</accession>
    <name>A0AAD8UA52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_723991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000168">
        <property type="protein sequence ID" value="KAK1710594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358873.1">
        <property type="nucleotide sequence ID" value="XM_060512614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA52"/>
    <dbReference type="GeneID" id="85396512"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF6">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041914669" evidence="2">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1710594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27421" checksum="FB28923841AF7EC4" modified="2024-05-29" version="1">MARTPLTWLITGCSSGFGLALIKLAEKQGHTIIATSHKPQKTPDLLPLDVNDLNSGDLIMDLEKANTLIDILSIYSPIDTVFFRPYRLIRRNSGIIVNISSGARLEGRESIGVYIATKAIIDRINKVLVKEMAPFSICVLIVTLGSFNINIGLTVRLASKPMLSDYDDIIFKVIATSVIEGFPADRDHVKVAKVKYKVVTGIGVGEGKESERMLPLGRDMAKRVDDVVGGWQRTMEVFGDVCNNVYLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAK5</accession>
    <name>A0AAD8UAK5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pathogen-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_181689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000211">
        <property type="protein sequence ID" value="KAK1707350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358038.1">
        <property type="nucleotide sequence ID" value="XM_060501528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAK5"/>
    <dbReference type="GeneID" id="85385427"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053218">
        <property type="entry name" value="Pathogen-related_defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31723:SF10">
        <property type="entry name" value="PATHOGEN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31723">
        <property type="entry name" value="PATHOGENESIS-RELATED FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32656" checksum="FBD323F3DD937EF7" modified="2024-05-29" version="1">MVIVNAQDPTPQAAAAQRNVLPDYVTTPNAVFSDEGVQWRYGRAPDYTRTRKVWREGRKMNHKAGSLEEIVENLVKNWEVEASFKTKLDDWRTVDHANYTFSVNGGAPQTGEHMLKVGTYNAVITPNEYYSPDYSDFASSHKTFKRMMPTFAWEVIEVYSGPPCIAFKWRHWGVMKNDYVGFNDKGDKVTAKAHGGQIDIEGVTIARVDDQLRLQGVDTWFDSLQMFRQIAPDGVVKKEAKTDNRGPEARFDEAVAQDVQLSAEDISKLHTDVVEGKRSGGCPVMMNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB66</accession>
    <name>A0AAD8UB66_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_29913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360811.1">
        <property type="nucleotide sequence ID" value="XM_060502236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB66"/>
    <dbReference type="GeneID" id="85386135"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041953324" evidence="6">
        <location>
            <begin position="17"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1717324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="539" mass="60130" checksum="025776FC52ABE390" modified="2024-05-29" version="1">MKVSLALLSCLAVAQAHFAFQPIQPPLRAEDEGEGILSKREAGFFEQLIDHNDPSLGTFQQRYWWNSTYWEGPGSPVVFFTPGESEAAPYTGYLTDRAITGAIAKAIGGAIVMVEHRNWGTSLPYAVQDTKNLQQHTMTNAVLDFANLARNVQLPFDKNGSSNAPQAPWVYTGGSYSGVLAAAIAKLAPGTFWAYHSSSGPVEATYDYWSYFLPMQNGMPKNCSRDFERIVDHVDNVLLTGSDDEIYSLKKKFGLQDLAHKEDFASALVGPLGYWQSIQLYSGYSAFYEMCDTVQGAIGNFSAPNTTYSADGVGLTKALNNYANWWSTNYLPGTCASYNIEEWSDPMNVACFDSFNATSPIYTDWSAENPFGRTWYWMTCNEPFFYWQTGAPKDRPSIVSRFVTPEYYQSQCDLFFPKQGEFTYASNAGKTAADLNKATDGWFFTNTTRLMWSNGEFDPWRSASVSSELRPGGPLKSRPGAPVHLIPGSRHCNDLLVRNGAVNEDMQEVITAEVDQMKAWVDTFYASKGKYRRRSTRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBB6</accession>
    <name>A0AAD8UBB6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ferric reductase like transmembrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_756668</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359867.1">
        <property type="nucleotide sequence ID" value="XM_060514780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBB6"/>
    <dbReference type="GeneID" id="85398678"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="328"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1713814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="630" mass="70989" checksum="3BB1C9A75D6E942F" modified="2024-05-29" version="1">MDSHRRRIAGLVADLIPTQILQQRAHAAATTGAAEATSTISPYHSNLAGVNQPVNMLFKDMLWASFGGMAIVVLVITISRILWAQLRHVSAMSVEGERQNYWKTAQWNWMPSLKKHLMYAPLWNKRHNKEIKLSSAIGIGTLPSRMHSVILGFYIASNMVYMFFLNWENANLYSFCAELRGRSGTLSVVNMVPLIILAGRNNPLIGMLHVSFDTYNLLHRWVGRMSVIEAVLHTIAWLIVQIADSGWDGVWHRMSNELFIGSGMAGTLALIVIMILSFSPVRHAFYETFLNVHIILAFFIFLMTYIHCAVAGLPGGLPQLPWMIAIFILWFLERMARIVRVAYMNWSDRGTTDAIVEAVPGECTRVTMNLPRYVDVKPGTHAYLRFKDIRPWDCHPFSIGWVEHIPDHRSLPLGVDEEKATLTAIDKKNTTTSISFIIGAQSGFTRDLYNVARQSGDRAIRMKACVEGPYSGHHSLDSYGHAVLFAGATGITHGISYLKPLIDGYNNGSVATRRITLVWIVRDYEALEWVRPWMDTILRLPNRKDILRIQLYITRPQNSQQIVSASNTVQMFPGRPNIPLIMKREVSEQQGAMCVHICGPGALADDVRSAVREVQDEGTVVDFVEESFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBH6</accession>
    <name>A0AAD8UBH6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_706874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361092.1">
        <property type="nucleotide sequence ID" value="XM_060511534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBH6"/>
    <dbReference type="GeneID" id="85395432"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000153">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="292"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="475" mass="52253" checksum="3E60C21FD672A03B" modified="2024-05-29" version="1">MSDANEKFEIAIIGGGIVGLITALGLLKRNIPVKIYEQSRSFREIGAGIGFTTNARQCMALLNPSIEVAVNAVATHNGENEDEPEECLRFNDGYTWDATRPDEEDMPLYNLDTGHDGFIGCHRAHLLDELVKFIPDDAVEFRKKLVNVTDEDIGGKVLLHFQDGTTSSADAVIGCDGIKSKVRQLVLGPDNPAAYPHSSHKVAYRALIPMDRAVAAIGSFKAYNEHCHTGPQAHVLHFAVAGGTILNFVAFADDTTNWDKIGDGVADMTSQTTRKEVADVFQDWGPTVKSLIDLLPDEVTKWVIFDTHDHPAPTYVKGRLCLAGDAAHASTPHHGAGAGMGVEDALALATLLENGTKILQSLPKPTQHGKSVLLEAMFRAYDTVRPPRGKWLVKSSREACEIYEWNHPDTMRDWDKCLKDLEERSHKIWDYDIEGMISRLEAEFADQVQSRSQPRQDASLPRAVAPQRVKDAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBU4</accession>
    <name>A0AAD8UBU4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_588916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000132">
        <property type="protein sequence ID" value="KAK1714107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359923.1">
        <property type="nucleotide sequence ID" value="XM_060506188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBU4"/>
    <dbReference type="GeneID" id="85390087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042192317" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="39"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="205" mass="22356" checksum="22EA2D265A2F4B97" modified="2024-05-29" version="1">MKAAYAIALLGATLASAQFTNQTRPFWLKFTPCTGGSGETYLTSCHSGAGQAGLCPETTEPVQEANRPTTHTNYFLNETQSDYNGHLLGALTWNQPIGNGDPVSSGMMLNLQIVSNGAIPIFSPGNTALFTLGFDENEKLFIYSRADDSKAVAGSQAPYGDEAYYRWHVCYTFVGNYYYRSLVWITAGPASNPTCEAVDVYREWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCI2</accession>
    <name>A0AAD8UCI2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_592719</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000197">
        <property type="protein sequence ID" value="KAK1708387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358265.1">
        <property type="nucleotide sequence ID" value="XM_060506558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCI2"/>
    <dbReference type="GeneID" id="85390457"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF16">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1708387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="64029" checksum="E875F98D901D0DD6" modified="2024-05-29" version="1">MSCGLSPPGTSGSKSRPSVQAKKSCTPCRIHRVKCDETKPACRRCSITGKVCDGYGGEDGGSAARRPSLPLLQTSSASPSRCDTHAGSAELSCTDKLHFEWFVSRTTNQLPGVFNSPFWKTLVLQASSTEPAILYAILALGAAHETSNTDACIVKREPPSPETADPQEHLSLQYYNKSIYHLQKHLRTPSTESIRVVLVVCTVYICMEFMQKRYKTGFLHFRHSLQLLGSLLKSSAPASSCDPADDWFLDVIPRLDIQATLLTNEFYQGAGTKHTSSIWPPLPPLFQSVRDASQSLDGLLFRAYQLQKDGAAAGPAEDAADIFELLATQQTLRNELESWIQAFDVFKARTWNFVTDRERIAYGPLPIYHTMAYIITNTSLNPGNELIFDLYTSHFASVVASARQLLEATSSATMPTPAAESSPEDYTQQTEHASDTGLVPPLFFTAVKCRVPRIRRQALELLLASQRQEGIWDAILSARIAKEVMVLEERGLYEGDIDEKRASPDFVIPVLPGPPRIHKLWIEVPEEPRGDILLSIQRIFPDGKRETLGRRFHAEYDYWTSVPVTLRVAKVTEQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCL9</accession>
    <name>A0AAD8UCL9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_590296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359309.1">
        <property type="nucleotide sequence ID" value="XM_060506320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCL9"/>
    <dbReference type="GeneID" id="85390219"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF6">
        <property type="entry name" value="CYTOCHROME P450 2C30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1712191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="62585" checksum="19BDD636BBE1CE7C" modified="2024-05-29" version="1">MESFTLVIFYLGILVVPGFLFSSLRRLVGWSTKAPADGKTSKPPARFPGPKQYPVVGRVHDLPRFAMWLKLKEWADEFGPIYQTSMLGQKFVIISDEGMAQDLLIKDGNKFAGRPQIRALIDHKLGPAYSALMDRHDTWKHQRKWVHAAMAAAHQHHFYGHIENEVKRWLVTLLVDPEKFHGNTRELTGRIISRLAWDDSTQGRAYGESAIETLTRMSISGPIVNTMTPLWHVADLVRYNPWRKYEVNREKNQRTWWLKTFRLAKARYLRGDLPSDTWTYRYFEQLQKSGNETLKQTEKAEDFAACMLGFQCLVGVVTISGPMQFFLMCMALHPEWLKKCQEEIDRVCGDRMPTRDDFAELSTVRACLKETLRWRSGVPLGVPHQCEQDSEFRGVKIEKGTIILACEWNINRVPEKYPDPEHYRPDRYLDPSFPTYQEPLSRYPNFRDGVGMHTFGWGRRTCLGQNLVDDEMFVAGAGVCWAFDMSLKKCPSTGKDVTFDTQATNSNVILEPLPFPMQFKIRSPERAKDVFEGYNAVRDALKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD61</accession>
    <name>A0AAD8UD61_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent rRNA helicase RRP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP-dependent rRNA helicase rrp3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_590111</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359391.1">
        <property type="nucleotide sequence ID" value="XM_060506303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD61"/>
    <dbReference type="GeneID" id="85390202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17954">
        <property type="entry name" value="DEADc_DDX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044765">
        <property type="entry name" value="DDX47/Rrp3_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="113"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="308"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="489"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1712273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="508" mass="55502" checksum="C8AB2F4E34EBE3DB" modified="2024-05-29" version="1">MPSSTTKQASLKANVPSSKRQKVAQKGSSSKVSRRVEAEASPSPPAESEAESESEDNVAADADSDVEINADVTADATEEVTKSFKELGVVESLCEACESLGYKKPTPIQAQSIPHALANRDIIGLAETGSGKTAAFALPVIQALLEKPQPFFGLVLAPTRELAAQIGAQFEALGSLINLRCAVIVGGLDFVSQAIALGKRPHILVATPGRLVDHLEKTKGFSLRSLKYLVMDEADRLLDMDFGPAITSLLKFLPRERRTFLFSATMSTKIESLSRASLRDPVRVSISSNKYQTVKGLIQHYCFVPHTQKDTYLIYLGNEFAGKRIIIFARTVAEVQRLSILLRALGFSAIPLHGQLNQTARLGALSRFREGTRQILVATDVAARGLDIPLVDVVINHDLPQDSKTMIHRIGRTARAGKSGIAISLVTQYDLEIYLRIEAALGKKLTEYPTQKDEVMVFQSRVEEAQRHARMEMKNLMENQGKKGSTLKGGKKGKGNKRRHDDMDAEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDN2</accession>
    <name>A0AAD8UDN2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_681327</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359849.1">
        <property type="nucleotide sequence ID" value="XM_060511213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDN2"/>
    <dbReference type="GeneID" id="85395112"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="376"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1713796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="592" mass="66847" checksum="813CFB85A9B45ECF" modified="2024-05-29" version="1">MGTSPNRRGRQAPTRSKAAGSAVRDSRISLHLSSERKNSSRRRIRNVLIGIFVSAILVACLRGYFSGHALGHMQYNPQVQFVDWHERREEVKDAFLTSWNAYKKHAWGNDVFHPLSKRGENMSPKGLGWIIVDSLDTMMLMNLTQPLADARRWLHRSLTWDQDQDVNTFETTIRMLGGLLSAHYLSTQLPHVASKRDSVYLSKAIDLADRLLVAFDSNSGIPYASVNIGKREGIASHADGGASSTAEAATVQLEMKYLSQLTGNDVYWKKAERVMKVLDDQRMEGGLLPIFVHPSHGQFTTREIRLGSRGDSYYEYLAKQYLQTGEAIYRDMWGDALGGIAKHLVTTTRNAALKFVAELPTGVGGPLSPKMDHLVCFLPGTIAMAATEGRPLAEARRDPGWTPQHEDDIELAIEIMNTCWGMYAVTDTSLAPEIAWFNATEADLQPGPGDRWLRKESSALSKWKKDFIIKPLDAHNLQRPETVESLFMMYRITGNAMYREWGWKIFQSFQAYTLVPDGEGYTSLNDVRTVPAATRDNMESFWLAETLKYLYLLFSPTDYMPLTEVVFNTEAHPFPRFAPRSSLKTGWERLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDP6</accession>
    <name>A0AAD8UDP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stress responsive A/B barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_742784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362307.1">
        <property type="nucleotide sequence ID" value="XM_060513120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDP6"/>
    <dbReference type="GeneID" id="85397018"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF17">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="14170" checksum="747E6B2317D19F59" modified="2024-05-29" version="1">MTIVHIVLFKFRTDVSEDHKSTFVRELKTLKSLPCVKDQRLIVGGPSITDPIERSKGYHFALLSFHQDRGALEAYQASPEHHRVTSTYLWPFKEDVTRFDFEVDQDDEYMCEFMAKGLANGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEK1</accession>
    <name>A0AAD8UEK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Squalene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the trichodiene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359944.1">
        <property type="nucleotide sequence ID" value="XM_060514765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEK1"/>
    <dbReference type="GeneID" id="85398663"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016838">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on phosphates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024652">
        <property type="entry name" value="Trichodiene_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06330">
        <property type="entry name" value="TRI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="333" mass="37667" checksum="2557DBEB1DA18238" modified="2024-05-29" version="1">MLQPPVIVQTDHLDQGTNLRQTLSCLIPTFLNAIKYVPPREVDKKALRISLLDRALQSGVHLGTDDASQMRFEAGLAVAAEMYPLHPFEIQIHIGLFTWYGFIIDDMNAELGQDLEQFQTRLLMGEQQPSALLQAFADVLKMTKKYYDPIVANLIVLSALAFVNSNAIEIRPQYHTIVLSKETVSWPYYFRDKEGLPEVYTYFCFYKETCPDIACFLPAAPEMGKFINLTNDILSFYKEEKAGEVRNYIHKQASSLNQSPLSILESAIMETVVAYNRSRAILKNSHPLRVFGSYRFPIVTPGPLQLSLSMSRPEPKAGVPASECVWISNAHTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEL6</accession>
    <name>A0AAD8UEL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_680792</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360153.1">
        <property type="nucleotide sequence ID" value="XM_060511208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEL6"/>
    <dbReference type="GeneID" id="85395107"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF66">
        <property type="entry name" value="MFS HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="42"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1715010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="536" mass="59867" checksum="6E8D72C90E7D2C02" modified="2024-05-29" version="1">MVKKAVMSRQVADNVGIAQAEAPRFEKVYWLREPHLRKLYFSTIFLMVASATTGYDGMLVNTSQQMSRWKDYFGDGVSDNNKLGILINMFNIGSIVSYFITPYVADNFGRKIAIVSGCCFMIVGGAVTAFCNGWGMYIGGRFILGFGNSLAQMASPLLLTEICHPQHRGPVTAIYNCLWNLGALIVASIGWGTSYVNNDWCWRSITFIQIVPSVIQLIGIWWVPESPRYLINKDRSEEALAVLAKHHAGGDLNNATVQFEFREMKETILMERNADKTTSYVDFLKTKGNRWRLAIIISLGIISQYSGNALFSNYMDAIYEGAGITEQNQKLAISTGKSILDLSCSIGAALTVDYFGRRPLFLTAISGMVASFVCWTITGAVFENSGNTNQGSGYAQLVFIWIFGIFYDIGFSGLLIAYGLEVLPFHLRAKGMMIMNITVQAILAIGNQTNKVAWDKLPNHWNFMLFYTLWDFCELVFVYFFYVETKGPTLEEISKIFDGDDAVAHVDLTQVEKEIDANIHEEDINTRAAHSEKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UES6</accession>
    <name>A0AAD8UES6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_627982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362937.1">
        <property type="nucleotide sequence ID" value="XM_060508671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UES6"/>
    <dbReference type="GeneID" id="85392570"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="20815" checksum="BA8FC03F498D129C" modified="2024-05-29" version="1">MVSPQITNLIIMLGMVQVSRKVPFEDPNVLNMCRAGYIASNIIIAIIYLYVQAQINKKKDLTTLKYVEPPAMGSAEEGKLVTTTIHAYDTTQLRQAFRSQAMGIAMMAFMHIYMKYTNPLLIQSIIPLKSALESNLVKIHVFGQPAAGDLKRPFKAPAGFMQGLQSGPAASDKKAIETAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF51</accession>
    <name>A0AAD8UF51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_40460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360645.1">
        <property type="nucleotide sequence ID" value="XM_060502863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF51"/>
    <dbReference type="GeneID" id="85386762"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF1">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="3">
        <location>
            <begin position="138"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="373" mass="41437" checksum="71DB4973C0D658BB" modified="2024-05-29" version="1">MPQAWRIYLYGAGSIAWRHGVAAESLGDDVQLFAADPSKLAREVLLAKFPKSTVYEDAEEMLASSPGQERDIVVVAVPPFLHHAATLHAFRSNRHVLCEKPLATSEKEMNEMLAASDEANRVFGECSFRYLGNKALDRARHLIETGGIGSVYHARFINRQPRARAGIEYQPSSRWFLEKEKSGGGIVFDWGVYDVTMFFDVLRPVAATVNHAWLAMPTTAADPSGVEISVETHAGASMTLKLQNGTVIPFYWERASGFHGDAQVALNIDGTAGGLTWEWVPTFDYKDEVDELEQGFKLAHYVDDNGNVKAREEKFPAFGWEDANQRPLLSFVDLIQGRDSVALSRNRLEFNFGVVSAIYKCASEGKPVHVQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFF8</accession>
    <name>A0AAD8UFF8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_634672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360603.1">
        <property type="nucleotide sequence ID" value="XM_060509115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFF8"/>
    <dbReference type="GeneID" id="85393014"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="77767" checksum="289C7FDFDBE1645C" modified="2024-05-29" version="1">MPRTLLLCFIHGFKGNEDTFHDFPDDLKRSVTKQLPDHRVESIVYPQYETKGELAQATEAFLAWLKERVMDVRKASVEKPWPPKDREVGVVLVAHSMGGFVAADSLFLAINERAQSNPSEDDPIFPLIQGILTFDTPYNGLARSMFVYGGFSNYQKVSSVFNVMTALSAAAPSTLARLGTRRAATSAVTTTATRNPGWKTWQLVAVRTGTVGAIAAGGVAAYVNREAIMKSLKGLNKNSVKEGYQQSVDALGQGLAYINRGNVGQSFAWLSDHFTFVGALMKQKELNRRLERMGALKGVGIHDFYASLGENGYWQGGYFVPERTFCAVPEESHPASSLFSRQVLPEVDDEVAAHMAMFQPGKHKGYEKMTEQAADLVIEWFKSEEPVVDDAKFRETPPEEVAEDAEVEETLEKAISNTEAPAEKSDDKIDEKFDEKEASKSTDDEMPDESPIDIAAAASLVPLPADGEGDLVGDINPENMTTEEKRTYMQHLFRIAQSTGTGVKGWLPGMPSMPGMPNMPNMPNMLNMPNMPKVPASVSSLGQASLPSVNIFRKSTPSQALADGEKPEADKTTDATGDVAKAEGDVVKTDSDAADNKNEAQETTSETVGNETAQAAAATGQLESQPADPVADDGKKKGWSLPSVNIFRKSTPSQAPATDTKEAAKVESDKKPEVGVADDGKVEGQSDPEAQTTGNEVAQAAAASGQLETADVGEDAKQTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFG7</accession>
    <name>A0AAD8UFG7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phytochrome chromophore attachment site domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360561.1">
        <property type="nucleotide sequence ID" value="XM_060514693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFG7"/>
    <dbReference type="GeneID" id="85398591"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phytochrome chromophore attachment site" evidence="1">
        <location>
            <begin position="203"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="619" mass="67790" checksum="4BA1B4514C01F272" modified="2024-05-29" version="1">MAQPAPPIEDDVQLHQNPDNLSEPAAIAIQSFGFLVVLTATEDNVSRLVVDCASDNSATFTGYSPNDLFDLFDFGSILERADVGTLMARLGLLREDKFDVGAAGGRAVFSLSILPKKSDKATRFWCSMHLTRNPPGPETIICEFEPHEDGSAPQMGPRSSTGDIVTKTPRMSRRVGKEGVELSTMQAIGIMSEIQASFAAIAGLAAVPDTIVATVEEVTGFDRVVLYRIDEFMAITILDTSDRESRGSQRCIHFTRPRRADNVSHQPPFPSQLRILHDRDAQPARLVYKNAESHQDESIHLDQSYLSRASPTFFEELASEDSKARSFLTIPINTFGKRWGLVVCYGYSPEGTRIPISRRQMCEFIGSTSGVAIERLSYASMLGHVESLQTQRSSIQNSAKNTAVSQDLLRLFGADFALMSTRGELGRLGEPSKELYHEATAIVRCIQPYRSESVIMSTDVPAELPDVGIATSARTIFGLLWAPLSTSTGDFVVFFRLKQLASSVPYDSASSSVASYLKPATQSALRWSDRQVRMATALGSLGRQLPLSQLPKESASVTIQSVLSLARIEPHVYGAVGSIVEGLNGTLQNLGEQHDAYDNVNQAYFSSRALEYLLNDLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFI0</accession>
    <name>A0AAD8UFI0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_581798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1722976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363031.1">
        <property type="nucleotide sequence ID" value="XM_060505490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFI0"/>
    <dbReference type="GeneID" id="85389389"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF26">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="339" mass="37282" checksum="2EA8839701D2F316" modified="2024-05-29" version="1">MSQKLIVVVGATGNQGGSVARRFLAAGYRVRALTRDTKSTSATALSALGSDVELVGADLEDVASIEEAFTGANVIFSVTNYWEPFFRPDCRMKAQEQGISCRKFAYDVELRQGRNIVDAAAKTVESLDKNGFLVSTLSHAEKCSGGKFKELYHFDSKAEVFPGYVNEKYPELAAKMSCIHTGYFYTSYNILPNSYFGKNSDGTFTMAFTTSPDKPVPHFSPVDDMGNFTYAVSQMPPGKAYMAEGTTATWPQFLETWAKVNGVQASYKQIRPEEMIEATGEHDTGIEVAYMFSYSSDPGYDGGMDLLTAADLAKAGIDCPMTTWEQWSKQNDWSSVLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFN9</accession>
    <name>A0AAD8UFN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_630126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362233.1">
        <property type="nucleotide sequence ID" value="XM_060508800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFN9"/>
    <dbReference type="GeneID" id="85392699"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="16763" checksum="2C9BECAD5850BF82" modified="2024-05-29" version="1">MTTQIPSIYKAVFLYWDPPCALWGAFMSFFTRDWMLDQFFLESHTGARDAAHDMLLYQGGGALVGCVILNGMLLRYTQDIGVWKIAQAAILAIDLSLLAGTYEVFGKQGRLSPTTWQVGDWVGMIITIGVTVTRISFLAELGFKEQKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFS2</accession>
    <name>A0AAD8UFS2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_633626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360899.1">
        <property type="nucleotide sequence ID" value="XM_060509049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFS2"/>
    <dbReference type="GeneID" id="85392948"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052742">
        <property type="entry name" value="Mito_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015416">
        <property type="entry name" value="Znf_H2C2_histone_UAS-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138:SF2">
        <property type="entry name" value="PROTEIN SPT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09337">
        <property type="entry name" value="zf-H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="612" mass="66550" checksum="519FE56F7387A2FF" modified="2024-05-29" version="1">MPAMLDDPASPTIYRVSGVTPYPDPMNPSLPADITPRQVTLRDRQTVATIIPFASRHEVPPSLVRYLSDQLNKEIEGGDTYPMMETMTAEQFGAYWFQNFGAVMMLGNIEQPHADLNDDMDWSRECLGSFYIKPNYPGRSSHVCNAGFLVTDASRNRGVGRLMGECYIDWAPKLGYTYSVFNLVYETNVASCKIWDALGFKRIGRVKGCGNLASYPGTLIDAIIYGRDLPVPGSNGAESEDLVSEERFDKIKFYLKYGRYPAGADRAEKSRLRSAATHYKLVGEGEAGGGGERLMLKDKEVVPDPRRQYEIAREVHAAGHGGINKTTATIAEKYHWSRIKETASDVIRNCTECKELGKTPAPGGGNGGGAKGRSAAALAAAATAASTTSSAPPVSVVNPLTNTSFHHTHSTSPPQQPLSPGPTSTVLSTADHVLSLQHQHPHHHHHLPPLSPPRSSPYAEVTSLPPSHTLRDPSASPLPRHPHHNPMLQDESFQPIDPQIIGGLQPPGPTSHHDLHHHHHHENPYNPYHPHHTDFQALLNATEAEEGVEGLGEMGVSAEEAAAVDRDLDMLIEQGDDDDVGVGVGVDGDADAVMGEKDGREKDVYSIEFING</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGJ6</accession>
    <name>A0AAD8UGJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_721409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362522.1">
        <property type="nucleotide sequence ID" value="XM_060512382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGJ6"/>
    <dbReference type="GeneID" id="85396280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058525">
        <property type="entry name" value="DUF8212"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="22"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="222"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="586" mass="65853" checksum="B291C04963828A03" modified="2024-05-29" version="1">MRLLETETLTLHEFVEGQVPEYAILSHTWGEEEVLFRDLENGPSDKAGWIKIQSACRVAYERGYDWLWIDTCCIDKASSSELSEAINSMFRWYKEAAICLAYLSDVVYSEPGTDECETTLAGSRWFTRGWTLQELLAPSSLDFYDRDWTLVGPRTLFRGVIEKKTGIESIYLSGERGLASASVAERMSWASERTTTRIEDVAYCLLGIFDVNMPLIYGEGIKAFQRLQEAIIRDNDDQSIFAWGNPHEGNVVRIPSPLDGWSLLASSPKDFTHSGDVIPIFHITTSARVRIENSGITFMTPLLAETPSKWVNGPSSTAFLAPLLCRRRTDIFNTIALSLHNGMSYYRVSNQLFKYPMTAWVNERLCSAFIYLKASRRFRDIGDERGYAPNWGCAIRTLPQGFTLGTPYSSTWGQHNDEMQSDVVPITERLVGSYGLASPIVIPLHHYGFEASLALVLQYQYMSTATGYSGSVIFDKAPSWMVNRVVSIPLGSTIEEIAETVRIESEAWPAEYVRRISGTNRRVKPASSIDLFDRSSLKTFTRFHVGVSTELVHGNLQIVDVEDSRGSNVSLEVDHNGIYTPVKSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGK6</accession>
    <name>A0AAD8UGK6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stress response protein ish1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_585907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361218.1">
        <property type="nucleotide sequence ID" value="XM_060505892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGK6"/>
    <dbReference type="GeneID" id="85389791"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018803">
        <property type="entry name" value="Ish1/Msc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10281">
        <property type="entry name" value="Ish1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042287635" description="Stress response protein ish1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1718718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="59678" checksum="03B7872E39D78C75" modified="2024-05-29" version="1">MRFLPAVLTALAAQGAIASSWFSKAAYNKWHETELERWLSDHDIPYPTPADRKDLEKLIENNWNDYVVSPYNSWDTDRLQNYLKAKGLETEGAAKANKESLVAQVQSSWYETSDQAQNAYLNVKDWILDSWTDSQLKAFADKHGVPVPQPRNRDSVLQKARANYETIAQKAGETASYPGNWLYETWSESDFKEWLDTHGFPAPQVTSRDKLIASVRRNSRLASLKAQEQAASASASAQQAYATLTDMVIDAWSESQLKEFADKNGIPVPQGTKANELRALVRKHRADFLNSNIAGKANSAFGAATSNVNQAAAKATDAASNAATEAFNEAVGTWSESRLKGYLGSRGVPVPQGSKTDELRALVRKNQHKAATGWSAWTYDDLSTENLRKYLASSSDAAVKNVADKKDATRDELVNAAQSAYSSASSAGGTSYASVTSYLSQATDAVKSNFFDTWSESELKSYLDSYGVNVPQGSTVNELRAYARKQYTYFKYGTSTPSETLFAKVAENVKDTWNWVSNQIGLGADAAQKKAAESKDKVKQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH59</accession>
    <name>A0AAD8UH59_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_587451</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360590.1">
        <property type="nucleotide sequence ID" value="XM_060506043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH59"/>
    <dbReference type="GeneID" id="85389942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000023">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF7">
        <property type="entry name" value="SUCCINATE SEMIALDEHYDE DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="500" mass="54875" checksum="1515633B3D3E2600" modified="2024-05-29" version="1">MAQDLPFKLANPDLLKTDAYVHGSWVEASSKKRFEIEDPGTGKVFASSPDFDRSDVDAVAKSSHEAFQTFRYENPRSRAKKLLEWDRLIRENRDDIAQVLTHESGKPLAEAQGELDYALGFTWWFAGEAERIRGNISTPSAPNRRVVVVKQPIGVAVALVPWNFPIAMILRKAGAALAAGCTMIAKPSPETPLTCLILAHLATKAGFGPGVFNVITTSLDNTPEVAEALCKHPLTKKVSFTGSTNIGSLIAKHCAEGLKKLTLELGGNCPFIIFDDCNQDQALEQLLALKWRHAGQACITANRVYVQDGIYEEFLEKLVERTKKIKMGHGTKSDTTMGPLTTPRAIPKAQAHVKDAVEAGAKVVHGGRKGTEVGLEAGYFHEPTILRDMKQSMLLSREETFAPVLGVYRFKTEDEAVQWANDTSMGLASYFFTKNIDRTWRLMENLDAGMIGMNTGNSSAAESPFGGMKQSGYGKESGKDVAIEEYLVSKTVTMTLEDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHF4</accession>
    <name>A0AAD8UHF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_634350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360755.1">
        <property type="nucleotide sequence ID" value="XM_060509089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHF4"/>
    <dbReference type="GeneID" id="85392988"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF15">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="4">
        <location>
            <begin position="329"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="845" mass="95017" checksum="0DD485F914733D5F" modified="2024-05-29" version="1">MSLLHWIKARHNLPLRERAILKLSGFNVKCANPLHEFQDSLRNRIALEPPIHSDATCDRCEKLRNDPDDYKLISGLRYWCLDCETTQADVCSTCVVVPGQGIDHDPAHRLVQVQPTACSVCEDVERLEVKPADMHRGPYKEFLVKGGTFKEVAETRSCGFCTFLWRLLAQSPPEGLKWPPDDDKEVQIRIRKQWRDWLNISVVSDLATEEEFEMRGEKYVRRGQNAADMEKEMLVGPSVAWSHEMPVSEITSEEEDRRTWQVGVCKVLPSSGSSEALQLAKSWLDNCCKRHSKCAGTPPHILPSRVLVLQGQDFSRVYLKETMGIEGSYAALSYCWGPGRPGLITIKDNYRDHQNFGIPINGLPETIRDAVHAARTLGLDYLWVDRLCIVQDSVEDWAHEAALMCAVYSGATLTLSADGSNSATQGLFQSNQTLSALDYKTYYDPGADDLVYIKRPSHASLSGRASDMTQPIDQRGWTMQERLMSPRVLHFTSEEMVWECNTLTECECRRESAMSTRELAPSGITTREGLYEHWRHIVREYAKRSLAYETDKMPALRGLVEKFQRVMQDLVGKDTDIKDEYLAGLWRNDLVEGLAWKPPTPGDLEGFLKATNHRRILNIGVDRDVDSEAWEKILAHRNRLEDWHQSGGYVAPTWSWAHLRGPMSYLYCRPLTPFIPYVNVVEANVVPVNANEPTGQVSSGFVTLEGRLVHGLRLSITQGIEVVVLLLGTRNFVPEKGGYGTVGGLSNPVKMSWNMPAERGIAEASEEDTGVAAGSPACELPGELVEAFVEDTEYPRFTTFLVLKESDLEKGKYERLGCFDVWGRNDVGVAKALFSSSVNETVTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHL9</accession>
    <name>A0AAD8UHL9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_585315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361474.1">
        <property type="nucleotide sequence ID" value="XM_060505837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHL9"/>
    <dbReference type="GeneID" id="85389736"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052820">
        <property type="entry name" value="PhiA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42047">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42047:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042016522" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23164" checksum="877FC01B25DFF347" modified="2024-05-29" version="1">MFAKLLSLLVISTTLASAASYQLRTFAPSEPSVHDKLVNVEEERFWIGLERPTTWCPDFSGGSCPPGNTTVVDGVFGRMKSMMSPGQLVYLDPFGVISYTAGDALTWNTMPHGSNFNCFEAVEIWDPADATKKLRLVKFINLGDPAASARPFFYSCPIEGKKHSFVRVRWTSQHGHREWGVDWDSQCTAMEGLILVESKVEIGAYQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW6</accession>
    <name>A0AAD8UHW6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Proteasome regulatory subunit C-terminal-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_755078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361639.1">
        <property type="nucleotide sequence ID" value="XM_060514567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW6"/>
    <dbReference type="GeneID" id="85398465"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="321"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="545"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="575" mass="63705" checksum="419B0A6224D0EF13" modified="2024-05-29" version="1">MPGKTPSRSGKDPLENGVRKNNKDADSKSKGKKGAKDGDEEMTVVVPPSKKAAAPPADTDGDVAMGDEAGADDAEVKIDPVVQAVADIKSNFALLDRAVALFDARFSLRALRSISTIRKRLTPDIIAQAIAESFPATVASGNVAKQLLIAIGRENVPLGRSSGPEMEVDSEPAKTKNGQKKDVKEIIPEVDIFLGILIQVHLYDTKQFQHGAEFSKQLTDRIHTLNRRTLDSLSAKVYFYYSMFCESLAPQPPSPQSPVVAIRPTLLAALRTAVLRKDIDTQASVIVLLLRSYLLTSHIAQADLLVSHTQFPENAANNQVARFLYYLGRIRAIQLRYTEAHEHLTAATRKAPSSACAVGFSQTATKLLLVVELLMGDIPERSTFRQPTLELSLHPYFLLVQAVRVGKVQNFETIIADHADTFRRDGTYSLILRLRQNVIKTGIRMMSLSYSRISLRDICIRLDLGSEESAEYIVAKAIRDGVIEATLDREHGYMKSKEVGDVYATREPGEAFHDRIRACLALHDESVKAMRFPMNQHRLELKNAQEAREREREMAKEIQEGDLDEDDLGGDFDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIT8</accession>
    <name>A0AAD8UIT8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_625933</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363632.1">
        <property type="nucleotide sequence ID" value="XM_060508523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIT8"/>
    <dbReference type="GeneID" id="85392422"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="78"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="331"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="411" mass="45311" checksum="9D511A2E17C08D73" modified="2024-05-29" version="1">MSNATTSAKIGKPPNNTRDYNIIRGIYRQYGVTTLDPSLGYLFAAKEPANAVHESKQGAIIAGMIIVLLAIIVPTAGRLWVRGRGAQTKFGWDDWVIIAAATLAVVYPILQILVVVDAGGGTHTWENTYDDYQFYSYYLTICRLLYYPTVGIIKISITLFIRRLVDTAYRTWRILADVFLVTVVAYVIAALFWSIFLCNPPRAVWDREFAGALAEPATCGNQFLSAKVLSIIHVVQSVLLLATPIIILWSIRIDRGKKIRLFIIWAAGGLTVTGGLLQQLQPFTSTDIFWDYTIILRWTVLDISMGIVTASLPVLDAAIMGSWHAAKSTLGLSNPDKQNSRGTKGTRGTNVETISSGPRKNYASSAENIVGKDDGLEMDVIQHNGPDDTGDNHSIPDTTGHDRRHRVNNMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIZ4</accession>
    <name>A0AAD8UIZ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_327092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364816.1">
        <property type="nucleotide sequence ID" value="XM_060502396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIZ4"/>
    <dbReference type="GeneID" id="85386295"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="995" mass="112395" checksum="6D52D67CF49FFC01" modified="2024-05-29" version="1">MRPPPISRSHGIVLTRGRWVLGRDWQALSQRHNYQPCHTAAALQQTPSWQLIRPFKRSPQSHEAPRASSRRDLIRIVRHERSIFSDLLLADAADLYRLPSEPPSESKLSNLRFLAQLRSPQLSVITAQEILRQVPELRPDIARLLCDSRQWQATLQQLSARGHTPANVSSWAWIIIPRDPDKRVERFLSRPGHKPLFVLIYLLTSRPYFQSSESLLGLLRYCNTWYAERQKSSNDAPQAFDLDSVITPVLFSKLLDKLCQHASRLQPDALPDIAELSVSYIKIIPLGHRQPDKAYKLQCQVLNRAIQAVSVLSRKSPYQYSSYNWTAVTKLLSLSSTSEKTLIIEEESYRAIRQVLLALPKTASERDTASTLASHWPPHRIMRDGMEEKSGPEAYQSRVVKAGIMMQEGGYSKKDFDLITDILGGMAPDGSPTVQTRANYPRHLRVEQGAWAAQIRTTRNAQEAWALFKHPPEPGMKPTFEVYRELIAKLSAKSAKSGHHNLPGDGREVFPYNDENLSDFERARTNPPSIRKIVEEMYNAGIPIRGSFLAGLIKQSPSVDVALHHVDCSSLEEGLKSSIRQSLKDYQGLTGSALTNPPHDILHAFIDLFCRLQPNRTSNTPSHISNKSMFSIHYAFQLAQMGWASTDVSGRAPWETILFNLGRSNIMVSNSMPSENNIEVLHLAVKALKMAEGHSGLSLNMITAFASVLRKAVQPRLAALLTKDVAKTPVHSEEQPSDEMATGSPRVEDAAASRTLDEDEEFLSLYQAQTSKIKNPKGRIYRLHGPSSKLSYRQILTPIFQREELGHDQTPIEAVQKASSQLKTAWRALATLGPAPKPDVNKLVTAATINTYMRTLAFLGDREEMVLLMWWIIREWTPKAGGDLSLAHARYLARAFRAFRAYAEPLLDQETVMALREEVTALSDSRNGGPMHWPSDEEVEEYIYEDEWGNHQNLHEVIKRGLAMRQEQSRLEEDTQENEASDKKYRIGVGRVRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJG7</accession>
    <name>A0AAD8UJG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_777010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365532.1">
        <property type="nucleotide sequence ID" value="XM_060515473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJG7"/>
    <dbReference type="GeneID" id="85399371"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF57">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="47"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="54445" checksum="B8F3B69BA4FEA449" modified="2024-05-29" version="1">MSTSEKDIKNGAAVDPSIEVEYASDPDRAGFDQAATKRLLRKIDWTLIPFLALLYLLSFLDRTNIGNARLAGLEKDLGMQGLDYNVALSVFFPWYVAAEIPSNLAMKRFRPSIWIPCIMIAWGICCTLMGLVNNYAGLLAARMALGLAEGGLFPGITYYITMWYRRHECGLRMAIFFSAATAAGAFGGLLARGIVEMRGIGGRPGWAWIFILEGILTLAVAIAAFFVMNDYPATAKFLTVAEKEEVTRRLEQDRSALADEFSMVYFKDAMKDWKIWVHMLITIGIYTPLYSYSLFLPTIVSGLGYTNETAQLMTVPPYIVACVCCISGGWVADRHKQRGIYMIFFCLIAMTGFIMLLSSQSNGVKYAGCFFAASGIYPNVPQGVAWNGNNIGGSVKRGVGIAMHVGFGNLGGAIAGFLYQAKDKPHYYPGHGTLLSTLTMSMLLSTFMTIYLRRENARRDREYKDPSQYTAEEKAAERHKGDNATFFRYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKW8</accession>
    <name>A0AAD8UKW8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_583239</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362390.1">
        <property type="nucleotide sequence ID" value="XM_060505637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKW8"/>
    <dbReference type="GeneID" id="85389536"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="149"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1722335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="320" mass="35370" checksum="E0352AC298A0954E" modified="2024-05-29" version="1">MTSSNNPNLGSGTGLPGTAPPFIQPLVACAMLVVYTAIYVAPLYISPASRPSPTLSRDDPVVIRTRIRSVLFSTASCSALTYLILARLPEDTLPYGPLHAMGYWPIGILESASCLLLTAILFAAPLYETLLIDGVWEGWRGLGPVTRVWTRLTTWRNIVMGPLTEEMLFRSASVPLMLCARMSLTKTVFLSPVIFGFAHVHHFYEFRISHPKVPLVAAVARSVLQFSYTSLFGAYATFLFLRSGSLLAIVLVHAFCNAMGLPRFWGAVEPYWHVSGHHTPADGRKWTVIYYVLLFTGAITWWRSLLPLTQTSASLFPQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM85</accession>
    <name>A0AAD8UM85_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_624641</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363981.1">
        <property type="nucleotide sequence ID" value="XM_060508456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM85"/>
    <dbReference type="GeneID" id="85392355"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="50"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="32347" checksum="5DF495BD5749F68E" modified="2024-05-29" version="1">MSPTSLHQGASKGFADAATYDAYRPSYPPAATQKFLEHLRLADVPHAKILDLAAGTGKMTEVLAARHEGFEVVAVEPHEGMRAELEKKGLRGVEVKDGFAAKLPLGEEWGDGAVVAQAFHWFATAESLKEIHRVLKPTAVLGFIWNIEDYNKPKHWKASTPWEQALNELVFTLGGDGQPRFRDFVWKDVFDTQLDANPLRAVKDVVLEGGRKMPLFSVPVGEEKVPFTVWLTPEAVWNRLRTLSQVAVLEGARAAAFKAEFDTILGGESVERNEKGEIALHGVTYFAWTSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNJ6</accession>
    <name>A0AAD8UNJ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonselective cation channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_347067</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364641.1">
        <property type="nucleotide sequence ID" value="XM_060502494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNJ6"/>
    <dbReference type="GeneID" id="85386393"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056337">
        <property type="entry name" value="LHD_YVC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052971">
        <property type="entry name" value="TRP_calcium_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056336">
        <property type="entry name" value="YVC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35859:SF1">
        <property type="entry name" value="NONSELECTIVE CATION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23190">
        <property type="entry name" value="LHD_TRPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23317">
        <property type="entry name" value="YVC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="YVC1 N-terminal linker helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium channel YVC1-like C-terminal transmembrane" evidence="4">
        <location>
            <begin position="268"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="718" mass="81918" checksum="56F0E0FBB4C0F440" modified="2024-05-29" version="1">MSERTRRARLQLPEERPLLQRNRASHTSEIQVPLYGCMVNPHSHLPVYTNIHRIRRDIISIVEDYLSLEQLRDVRINIAVVRPLVDKLYELDDISIVYCLLVNRAQFLYEQSHLNNRQNVNYSRAALCELVATRILRRFSEDNEGPDGLVLLAHILVAGFEPFQMAPAGIREAASTESYRSYNRMLPSLEVAILTESKYFLSATPCQKVVDAIYEGRIVYTPSSFMDIIPDHYKLKPISLYNPREGPLLDQYRLLVPRTRNILEVFQFLILLALYLFVMAERKPETFTVLEGCFAVYAFGWSLDQFATILEHGWHVYTQNLWSFLDVGFIGIYVVYAVLRIHGARVGELVPKQQALDVLAMGAPVLVPRLAFNLLSDNLVFLSLRSMMSDFVLLTFLSAWCFGGFLLSLLWLGEGAHPPVTISKWMLWIWFGLDGTGINESVQFHPILGPVLMVAFAFLGNTLFLTILVSMLSNTFSTIVKNATAEIMFRKAVLTLEGVKGDAIFAYQPPFNILAVFILIPLKFILTPRWFHKIHVASVRLVNLPLLLIIAVAERRILWPAPQPEKKQSSSLTLYPRVKQWFWEKWRITAHRDIRAVFDLPPPESVEEEIAVDDELTHHLIRRQFTRSITNDTMRKKSPLRRDSMFPGVSSKLRGSFTGSEDMQDVGSRLDSLEQTSLRIEALLARMLDGEDYSDRGFGTGESSTLRDGEAPLTQSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP02</accession>
    <name>A0AAD8UP02_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_327737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364836.1">
        <property type="nucleotide sequence ID" value="XM_060502398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP02"/>
    <dbReference type="GeneID" id="85386297"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="40107" checksum="0245D089B0AF8C62" modified="2024-05-29" version="1">MTERIRRAHHKSRLGCRRCKTRRIKCDEVQPACGGCTKANLRPPVLVDTMTDGLKARFFRHYLDMTAAYPSTDQQSWSSWITDLAVTDSTLMDAVIGFAAFHLRRSSASDDSSGNGSNTYAVAVSEASHAYMARAIEAHSRLIVREGINAQNAPVVMATCTIIMFHTSANQSFLDSSGGGPGAETGYRVPHHWFTPFRNVNALLKVALPGIRNSRIGHLYKPERQTSSQQNETLGPARPGTFDFLLEDLNEDETDPETAKAYRIAVDSLDKIQGSALQRDLLRFPAHVPPRLVELLEAEDPRTLAIVGYFFMLLRRATHLWWAQGAAEKEFDGVMGVLPREWWPKMAWAIEEFKWTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP42</accession>
    <name>A0AAD8UP42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_573544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366973.1">
        <property type="nucleotide sequence ID" value="XM_060504625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP42"/>
    <dbReference type="GeneID" id="85388524"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF80">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041913843" evidence="2">
        <location>
            <begin position="22"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="384" mass="40297" checksum="62D5875DB9821EFC" modified="2024-05-29" version="1">MVFSLRKAFAALLATTATVYALPSDSSSSTESTVNTTSLAATSSNSTVCNNSPTLCSRKYNNITHMGAHDSAFLRDASTSNSIAGNQYYNATVALNSGLRLLQAQVHLVNGTSGSVLQLCHTTCSLLDAGTLENWLSAIKDWMDKHTDDVVTILLVNSDNQAASAFGKVFESSGISKYGYKPSTSSATSSWPTLQTMIDADTRLVTFVASITADTDYPYLLPEFSYVFETAYEVTSAAGFNCTIDRPSTYSTAAAAVSANMLPLMNHFQYQTLATDILIPDVSDIDTTNSASTSTAGNLGLHAQTCKSQWGTKPVFVLVDFFNKGPAIDAADNLNGLSSSDISGRSSSNSATASSSSGKSAGRAPGGMETGALVAFLAAAVFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP60</accession>
    <name>A0AAD8UP60_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_739101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1728012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368067.1">
        <property type="nucleotide sequence ID" value="XM_060513035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP60"/>
    <dbReference type="GeneID" id="85396933"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF112">
        <property type="entry name" value="FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G02370)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="78"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1728012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="31555" checksum="4E72A96A76CBA8FB" modified="2024-05-29" version="1">MSPSWTHLVRFVAEEDNEIHLGQIDASQYPDVGLATLDGQKVRANVVVGDVFDGRVTEDVLHIKHLLSPVTADQVPIIRCMGLNYRDHAKEASMPIPEVPVLFIKPRTALTGPYPSTINIPKISQDGSSDYEAELSLVLSKSGRDIPEEEAVDYVLGYTCSNDVSARKQQFKNSQWSFSKGLDGSCPIGPVLVAKSAMEDPHSLQIKAIYNDQVVQDSNTKEMIFTIPKMISFLSQGTTLEKGTIIMTGTGPGIGVMRDPPITLRDGDDIRIEISEIGTLVNRVRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPH9</accession>
    <name>A0AAD8UPH9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene synthase</fullName>
            <ecNumber evidence="4">4.2.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_693029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the terpene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.-" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368262.1">
        <property type="nucleotide sequence ID" value="XM_060511334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPH9"/>
    <dbReference type="GeneID" id="85395232"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034686">
        <property type="entry name" value="Terpene_cyclase-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201:SF4">
        <property type="entry name" value="BETA-PINACENE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35201">
        <property type="entry name" value="TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042190338" description="Terpene synthase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="38595" checksum="687CFA6BD591861E" modified="2024-05-29" version="1">MISLHALASFILPAQSTSLKVFDQSAKSGKRSYNPSNPPSAAQFTAKIHPREREVSAEVNGFFLDHWPFPDAKSRKKFVAAGFSQVTCFYYPTALDDRISFACHLLTLLFLIDDLLEDMSFEAGSSYNERLISLSKGVSLPDRSVPVEWITYDLWNDMRACDEALANEILEPVITFMRAQTDKTRLQIKELGHYLKYREKDVGKALLSALMRFSMKLHLSPEDLNSVEDIEINCSKHISVVNDIYSWEKELKASQIGHKEGSALCSSVAVLASETSLDYSASKRILWIMCREWEILHIQLVTSRLSSGEGCSPDLQAFMKGLEYQMSGNEAWSSITPRYHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPI8</accession>
    <name>A0AAD8UPI8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="12">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_561677</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368277.1">
        <property type="nucleotide sequence ID" value="XM_060503567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPI8"/>
    <dbReference type="GeneID" id="85387466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF17">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042142553" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="14">
        <location>
            <begin position="20"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="15">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1728222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="27928" checksum="97B381E67E7902A3" modified="2024-05-29" version="1" fragment="single">MQFSFTAAALATLIGYSAAHTLTIDVWVNGEDQGDGRSTGTGTTKYIRSPDNNNPVKDITSDAIVCNVNGAKAQTGFVKAAAGDEFKFEWYHNSRGDDIIDLSHKGPISTWIAPYTEGSGAEAIWTKIQESTYEGGKWAVETLVANKGMSPSVTIPSTLKAGKYLVRQEIIAHHESDTTYDVNPARGAQFYPACAQFEITGTGSDVPPQNFDFTTGYKYTDAGIHFNLYSADASTYKAPGPEVWTGGSGSGSAPASSAAAPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQG7</accession>
    <name>A0AAD8UQG7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_619760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365556.1">
        <property type="nucleotide sequence ID" value="XM_060508149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQG7"/>
    <dbReference type="GeneID" id="85392048"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042130456" description="Secreted protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7477" checksum="D6BF2D91968BB09C" modified="2024-05-29" version="1">MSHFAARRISLLLCSLISLGPCRTCPNEYSEDEGGILLVCHAGAMPGSSPTLRPSHTPKKLSTLVPDTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URD9</accession>
    <name>A0AAD8URD9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">dihydroxy-acid dehydratase</fullName>
            <ecNumber evidence="14">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_616295</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366378.1">
        <property type="nucleotide sequence ID" value="XM_060507964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URD9"/>
    <dbReference type="GeneID" id="85391863"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009082">
        <property type="term" value="P:branched-chain amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.80:FF:000001">
        <property type="entry name" value="Dihydroxy-acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="entry name" value="IlvD/EDD C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050165">
        <property type="entry name" value="DHAD_IlvD/Edd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056740">
        <property type="entry name" value="ILV_EDD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="ILV_EDD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002068">
        <property type="entry name" value="PRK00911.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000:SF13">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21000">
        <property type="entry name" value="DIHYDROXY-ACID DEHYDRATASE DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24877">
        <property type="entry name" value="ILV_EDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="IlvD/EDD N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase N-terminal" evidence="17">
        <location>
            <begin position="17"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroxy-acid/6-phosphogluconate dehydratase C-terminal" evidence="18">
        <location>
            <begin position="359"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1726323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="560" mass="59876" checksum="430D34E3E31080A6" modified="2024-05-29" version="1">MLYGAGVPNKEMMKKAPHVGIATVWWEGNPCNTHLLDFGKIVKKAVEKQGMLGWQFNTVGVSDAITMGGEGMRFSLQTREIIADSIESVTCAQHHDANISIPGCDKNMPGTIMAAARHNRPFIMIYGGTIMKGHSDLLEKPINISTCYEARGAFTYDRLHAKTNPGTEGRTPSDVLDDIEQHACPGAGACGGMYTANTMATAIEAMGLSLPGSSSYPALSPEKARECERAAATIRITMEKDLRPRKLMTRAAFENALVLTMILGGSTNGVLHFLAMANTADVPLTIDDIDRTSNRIPFLADLAPSGKYYMEDLYKVGGTPSVLKMLVAANLIDGSIMTVTGRTLAENVADWPSLDPNQKIIRPLSNPIKATGHIRILRGNLAPEGAVAKITGKEGLTFTGKARVFDKEHELDVALSAGSIRREDGNLVLIVRYEGPKGGPGMPEQLRASAAIMGAGLDNVALVTDGRYSGASHGFIIGHVCPEAAVGGPLALVKNGDTVTINGETNRIDAVDVDEAEMERRKKEWKAPLPHVRRGALGKYARLVGDASHGAVTDAADPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USE8</accession>
    <name>A0AAD8USE8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366501.1">
        <property type="nucleotide sequence ID" value="XM_060504724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USE8"/>
    <dbReference type="GeneID" id="85388623"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF2">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="42870" checksum="647AC31A9DC0A4FB" modified="2024-05-29" version="1">MSSRKRTCYVCRMVLDNPHAQLGSMCIPCGEFNLAERALSLPENMSLKDKTAVVTGGRVNLGFHTALRLLRCGAAVIVSSRYPEDALSRYQQEADFDKWAQKLRIIGADFRAAADAFALVQSIKKTLQQEGWDLDHLINNAAQTLTDPLEKEERAIEHERFLLDKPSSDGKGVVVRQGYSPRARGGAGSLPDGVAGKVSGSIAGPSAPKNTTLSDSMSKLQVSGVETPTPSSWVQSLSEIPYEDVITAHSVNTFVPLILIRELLPSMRKGGHIVNVSSREGIFESAYRTPAKHSKHVHTNMSKAGLNMITETEAPTAWKLGVAMNTVDPGYMSAAPEFEQAYGGERPIGWEDGAARVLWPIARAGRKGSYSPPIRGQFLKHYGGVRVDTRLGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USQ9</accession>
    <name>A0AAD8USQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hpt domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_649786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367259.1">
        <property type="nucleotide sequence ID" value="XM_060510314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USQ9"/>
    <dbReference type="GeneID" id="85394213"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043424">
        <property type="term" value="F:protein histidine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.160:FF:000007">
        <property type="entry name" value="Multistep phosphorelay regulator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045871">
        <property type="entry name" value="AHP1-5/YPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242:SF52">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="4">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="155" mass="17668" checksum="840D471ADF64CBA6" modified="2024-05-29" version="1">MPASEDKSDDGPLSTPDFGDAIDSVTFGQILEMDEDENDRDFSQSIVFGFFEQAEETFEQMDEALEEKDLEKLSSLGHFLKGSSATLGLVKVRDSCEKIQRYGKKENEDGTAEPDEKLCLERIEKTLKDLKTEYEDAEKLLKKFFGTEEEEEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UT55</accession>
    <name>A0AAD8UT55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_650167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366724.1">
        <property type="nucleotide sequence ID" value="XM_060510349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UT55"/>
    <dbReference type="GeneID" id="85394248"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="25667" checksum="E406C6A1CD2443BC" modified="2024-05-29" version="1">MVTSLKRSPSRAILCIHGGGASPDIFRFQLAGFRAALKEDFEFVFATAPHVAVPGPDVLPFFAGMKSFFSWFRKGATDTEGEVAVFNEAIKMAVQDWQLENEHVKIVGVLGFSQGGLASTVLLWEQEVGLVPWLPRLEFGVLVCCAYSDVATDYIRSKSEGGDVAKISVPTLHLHGSQDCNLGQARNTLATHYSSKVAHVINFEGGHHIPQKREDIIKMTNHIRHLGKKDIMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTV0</accession>
    <name>A0AAD8UTV0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_717997</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367069.1">
        <property type="nucleotide sequence ID" value="XM_060512011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTV0"/>
    <dbReference type="GeneID" id="85395909"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1727014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="299" mass="31926" checksum="039DBF54352CBA3F" modified="2024-05-29" version="1">MADKMGSFTEFLEFIMTPSTPVILIGAAIVLLFPVLLHYILIKSTPYTTLPSVLLLGPAGAGKTALLTLFERGDAPATTHTSQRPQTVELTASRDSKTAQSFRNHDDTSGTHTKFLLVDTPGHGKLRNYALGKLASGAGAGNSKNSKLKAIVFMVDAAAIGENEALAPTASYLYEVLLGLQKRAASSKSSKPPPPIPVLVAANKTDLFTALPGALVKSNLEAEITRIRSSRSKGLLDSGVGIDDVGSEEHDDWLGAYGTEKFTFDQLREFDVEVDVIAGNVTGSATGPDKWWSWIAQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWZ6</accession>
    <name>A0AAD8UWZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367940.1">
        <property type="nucleotide sequence ID" value="XM_060510255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWZ6"/>
    <dbReference type="GeneID" id="85394154"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042057509" evidence="1">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="155" mass="16865" checksum="2818ACCCE51A6053" modified="2024-05-29" version="1">MRYTTALIAALQVAGFVQASPILSNRDVATPVDSQALDVRIPGDISNLDADKIVDLEVRGIEKRATDITLSADTGYYKRVAYKGAVILLHLFYDLAVNHVVFYWTIDGTTPAPGSIPLAFDDPIGGGFPLRQYTHDTRYNLGSAMRPGDVIKVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UX21</accession>
    <name>A0AAD8UX21_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-ornithine N(5)-monooxygenase [NAD(P)H]</fullName>
            <ecNumber evidence="4">1.14.13.196</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_569963</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41512"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:41508"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78275"/>
            <dbReference type="EC" id="1.14.13.196"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.196" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368764.1">
        <property type="nucleotide sequence ID" value="XM_060504251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UX21"/>
    <dbReference type="GeneID" id="85388150"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025700">
        <property type="entry name" value="Lys/Orn_oxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13434">
        <property type="entry name" value="Lys_Orn_oxgnase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="545" mass="61414" checksum="9D1942CAE7DEEFFF" modified="2024-05-29" version="1">MTEAFIHDVLIIGAGPCGLAVASRLCEHSPSALFTDEEHQRYHWIRKYGRRMPLKNRRNGNIIEKRTPERSQRYSTLVLDATGDEWMNRWNRLFKTFDITHLRSPMFFHVDPSDRDALLARAHERNQENELQELRACVGKEISKHLRKARLKSRNPKQHAVVEVDERDRKDYFTPPTNLFANHCECIVDRYGLREGLIQNEKVEDIQYRTIKQVSPDANLFAVHTNKGTHYARTVVLAVGPANAPTIPPVLGLNSEPCCAAPPQVCHSMQIQKFPDPVVQVKISAKKTTNVLVVGGGLTSAQLSDLAIRRGVTKVWHLMRGPCKVKPFDIDLAWMGKFRNVEQAYFWSADSDEERLQQIQSARGGGSITPPYQKRLKQHIAKGSLRLLTNTKLSEARFDEEQKVWNVKTEPPAAEGDLPGMDFIYFATGVQTDYASLPYMQTMLQEHPIHGHGGLPCIDDDLKWSKDVPLFISGRLAALRLGPGAANLAGARAGAERIAWAIEDVLPDRTGDVPEEADMSDEKMRFVTGRGNRFDSLITVGDGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXN9</accession>
    <name>A0AAD8UXN9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS7m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_570464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368480.1">
        <property type="nucleotide sequence ID" value="XM_060504306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXN9"/>
    <dbReference type="GeneID" id="85388205"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000006">
        <property type="entry name" value="37S ribosomal protein S7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="9">
        <location>
            <begin position="165"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="37272" checksum="501225531EB0CFB0" modified="2024-05-29" version="1">MSLRPSLQTACRALALRSRPLAQRQEPLIWAATKRGYSDELRKGERSQIPVLKKTENAAFPQGQEVPESAPGQQQPTNEALEAAAALSELAEAAKGHSTGLQGGLTEAQEQMLYAEGAIPPTQSDGNGQRDLEIIASGGLLAQAGDAAEVAPSRSYKFPLPTLPLPPHSHLKSRYHPVLDQLTNLMMRDGKKAQAQRNMAMVLNFLRTSPPPIINPKYPLLPGAPPPAHLPLNPVLYLTLAVDSVAPLIKIRRIAGGAGGGRPLELPAPLAVRQRRRAAFQWILDVVNKKPSKGSGRTQFAHRVADELIAVTEGRSSVWEKRLALHKLGTATRANLTAKPVKQNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X889</accession>
    <name>A0AAD8X889_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_175686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000207">
        <property type="protein sequence ID" value="KAK1707552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358089.1">
        <property type="nucleotide sequence ID" value="XM_060501492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X889"/>
    <dbReference type="GeneID" id="85385391"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029010">
        <property type="entry name" value="ThuA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469:SF2">
        <property type="entry name" value="GALACTOSE-BINDING DOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40469">
        <property type="entry name" value="SECRETED GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06283">
        <property type="entry name" value="ThuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThuA-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27570" checksum="882C4B2724252BBF" modified="2024-05-29" version="1">MTPTSKPTREPFRVLAFSKTSGYRHDCISAAVSAVKALGERTGLFTVDASEDAEAYINPQSLATYATVVFLHCTGAFLNVEQLSALKGHVNSGGGFVGVHAAASGLREDEWYGKLVGAHFDQHPPPEEGTCVIEDPGHFIMRRGGGNHLAEACKDVRKQWTDEWYNFLSHPRDNDNLHILARGDPTSFNGGSMGDDHPLVWCQEFDGGRSFYTALGHYEQAYEDKWFVGQILRAILWTARREDEVIPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9Q6</accession>
    <name>A0AAD8X9Q6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_734976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359362.1">
        <property type="nucleotide sequence ID" value="XM_060512958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9Q6"/>
    <dbReference type="GeneID" id="85396856"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="23392" checksum="3A2553517963FAA9" modified="2024-05-29" version="1">MAKQQRDGHTATRRTSLKYMKASSNHGVARAQLRLNALRIFPKCPAAKLKANPIFFGSDLERLALGEDCHELHLAAASMDWVGDLQYKAKVAESLKRPRFKSSGGLLRHQGPSQRFTLNIQEDSDDMDYHTTVRAYGSLFCQKGDELTTCVLYYNKGQGFLEYFYIPRHQLPWKKQYRIPLQHSLSGYDSRPLDWVVVEDVNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAC7</accession>
    <name>A0AAD8XAC7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_595209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000277">
        <property type="protein sequence ID" value="KAK1703661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357324.1">
        <property type="nucleotide sequence ID" value="XM_060506774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAC7"/>
    <dbReference type="GeneID" id="85390673"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF9">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="127"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1703661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="565" mass="63570" checksum="1CBFD89C079DE1B6" modified="2024-05-29" version="1">MPRKFDVTATKYDSGRPLDVEETILLIQGRSSEQSWQVRLQQANAWIHHCLDNHQCNGGLAAKTSQDKYENKVGDKNENRPEKGESSGARYQNSQTPKLPRRVLDLRQFDSEKKLRLIDSMTDYGVYACLSYTWGRQNTGVTTTQNLRHRLDNLPFDSLPQTYKDAVTVAAFLEIPFLWIDGLCIIQGDADFKDWAEQSSQMAEIYGNAVLVIAAADSNSVEEGFLSTPQLPRELVKFQSSDLENLNSGREGTALTVFARALPDHSWLGWSTLAEPKSRGTLSRSWCFQEEVLASRLLTFFGGEMNFQCLEDEYRCECAFPAAPLGLVTIKELYEPRLALGDMETTNWMWQSTVEHYTRRRLTVATDRLTALSGVARVVQSGLCTKYAAGHWLDRDFLCSLCWAPVRNRETERTFSKDYVAPSWSWAAHNGPITMWIPYGGSEEPVTPRFLNKTVVRNVDITPATEDDTGAVIGGSITVSGVFLDISVTMTSREQSAGVMIRSSEKIPFYFDRPTEAVRDTDNMPSGPAHYCERVGFTDFDATASDRSMKFFKGFRVSSRTAIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAT3</accession>
    <name>A0AAD8XAT3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_682133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359486.1">
        <property type="nucleotide sequence ID" value="XM_060511218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAT3"/>
    <dbReference type="GeneID" id="85395117"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26639">
        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="119"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="684" mass="76972" checksum="93167E89EB4B5D14" modified="2024-05-29" version="1">MLANDTQFFKQSLRSEYWINFNVDKKFSLAGVYGPELDSEDKELVRTWASTKGASKTAPAQTQPSSLYRSILDPVEIRVLEILPGTGDDGLRGRLHHCSLELKASFALAVDGSATPMAYTALSYTWGPNVFDEAIECEGHVKNITKSLAVALRAFRQEDRSVVMWIDQICINQDDNEEKAQQIPLMSRIYQNAMNTVIWLGESTSNSASAIKLLEDVRLLLQFTEKTIGPDEFEGLNLPLKDSEVWGALWDFLSRPWFTRLWIIQEVILSFDSWVVCGNHMTTWDVLSLACLHLWTCGISRWLGEKFNSGSRALDFQRDLCESVQHLSSMKSSYHSAAMPLFDLLIESREAKCYDNRDKVYGLLGVCQDQDRSAIKPSYADEFPVTRLYRDITTRHLDDNKGSLRLGVVLTCVDHESPDLPSWVPDWRNPRRTHSLGHSTTTTTPYMACGHLTIEIGRLHPPLESKNKDELRLHGVSVDTIAKVGTTSTNPELSLDDPTTANGDLKDMCFFVAELQEYPGHETVFSAFWQTLVAGKDATEMAKAPIAYEEIISLLLDASTGLSPSLPGQTYSARQRRPAGKGKLQLANLKERTAGKTFQDVRTSMVHARRNRRLCFTAKGYLGLVPETSKVGDEIHILDGCHIPYLLRKVDHRRHRLVGECYVHGIMRGEAVHDNQSMDEIVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBV7</accession>
    <name>A0AAD8XBV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_755119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361567.1">
        <property type="nucleotide sequence ID" value="XM_060514570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBV7"/>
    <dbReference type="GeneID" id="85398468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054390" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="20444" checksum="B9B9EEA715987DCD" modified="2024-05-29" version="1">MQLISLTSVVLASWAFQQAAALPEIQENTNIITVAQSVQEKHPEAFAAFQKSNLINLVATNEKRQAVPGDGNPDPNRPPVIPENIFLLQCSEAGFLGECLSWGAPPGRCVNYSSFNKTQAFLDKYENQTTSLSSNTGGLCQFYKFINCNNKGDDRGVSLSYNYNLAVADDQGYSGDYDNQISSWRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBX6</accession>
    <name>A0AAD8XBX6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_743226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361627.1">
        <property type="nucleotide sequence ID" value="XM_060513133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBX6"/>
    <dbReference type="GeneID" id="85397031"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF92">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="73"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1720116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="383" mass="42918" checksum="365F520F69E5A31A" modified="2024-05-29" version="1">MGIVYPQPSEFIQAMSTSLCIPWRAPALPYLRPCSAFTHVQEGRPMGATFKDKTTGWVTILTAGAVLAASLHLRINIQGRKLQISDYFLCLAWCSAVVTASFDIQFTVMGALHQNIKINLDGFKGNDNEVMLIMRLFWASSIPFFTTFYLCKGALLAVYIQIFPIFMYYRRMMLWTAIVYVGLAYLVSMILLFTICLPLSKNWSVEDRVVGTENVMCSASSPAIVFQVGWALHFFGDILIFCLPWLILPDLKIKRALKIGVYCTFGLGIINMTFSLVRFITIQTASTCADGRAAELWSELDVNIGLLVATLPCLRPYFRSNRNAGYSDKSNAYNYKSTVKTLQITRMSRFDVVSEPAYDLNVDLEHVAACSTTTQSQKSSETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC13</accession>
    <name>A0AAD8XC13_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000092">
        <property type="protein sequence ID" value="KAK1720221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361732.1">
        <property type="nucleotide sequence ID" value="XM_060508907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC13"/>
    <dbReference type="GeneID" id="85392806"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="22447" checksum="77F4E9590B124C41" modified="2024-05-29" version="1">MAAWPASPLDDPTQSPALNCRHTPKRQNFYSPEPRRAQIETFHKVANRLLSRSPTTCAHHPKSQTLPVIQTCAVETWRQLTLSFPPVHFDSRLFHHFHRKDSHRSHKRPPAVPLSPVKYRPEKAKATGPNGLLPVIDTKPAYKSVSRLISSRIEVQASQAPRTDPLLREQILGGLAIFTVRLRRPKFQVGVQVGSQALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCA6</accession>
    <name>A0AAD8XCA6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_723645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000148">
        <property type="protein sequence ID" value="KAK1712260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359378.1">
        <property type="nucleotide sequence ID" value="XM_060512583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCA6"/>
    <dbReference type="GeneID" id="85396481"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF9">
        <property type="entry name" value="EPIMERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="26892" checksum="9ECF1F52A07D261B" modified="2024-05-29" version="1">MKLIIAGASGFVGTELLKQSLRIPDFKTVVALTRQPLKIRAETSPDVNHSKLKNIVVDGYDQYSAETKAELATADACIWTVAITPSKSTLYDWDEIHRVCYESPLASFRAILEARGSSTASNKNTPFRFMYMSGAKTERDQSKIPSFKPEYSLLRGKTETAILAFAKEHESQLDACIVKPGLITAPNDFLKMALAYTLWWTVSLPSIGVRQISTAMLSQSLFGFEKDTLENDDLLRLGESEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCY2</accession>
    <name>A0AAD8XCY2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_61584</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360158.1">
        <property type="nucleotide sequence ID" value="XM_060507924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCY2"/>
    <dbReference type="GeneID" id="85391823"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03128">
        <property type="entry name" value="GAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003190" description="xylan 1,4-beta-xylosidase" evidence="12">
        <location>
            <begin position="27"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="13">
        <location>
            <begin position="709"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1715015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="802" mass="87091" checksum="A52247A8C97448B0" modified="2024-05-29" version="1">MYKLIRNHLLLLPGTILAAGSGPSDQQKPLTSRTCLTPLPASDPRSGASNFPDCTRDPLCSIKVCDESLSANQRAKALVAELTIWEKLDNLVNEAPGVPRLGIPPYEWWSEGLHGVASSPGTKFAKSGNFSYATSFPQPIVIGSAFNDELVEAIGAVVSKEARAFSNDGRSGLDLYSPNINAFKDPRWGRGQETPGEDPFHLQNYVAAMLTGLEGSSDPSNKNLIATCKHYAANDFEHYNGVDRAGFNAIITTQDLSEYYLPPFKTCAVEKNVGSFMCSYNGINGTPLCANAYLLEDILRGHWRWNGEGQYVSTDCDCVALMVSYHHYAPDLGHAAAWSMKAGTDLECNAFPGSEALQLAWNQSLISEEEVDRSLTRMYTALISVGQFDAAREQPLRSLLWRDVDTEEARELAYRAAVEGSVLLKNDGILPLSADSGKKFALVGPWAKATTQMQGNYYGPAPYLVSPYQAAQDLGLDFTYTLGSMINASDDSLSDALKSAKEADVVIFAGGVDNTLEAETLDRKTLAWPESQLELLRALAEFGKPVIVLQFGGGQVDDTELLASDSISAILWGGYPGQSGGKAIFDLLFGREAPSGRLSVTQYPAIYNEAVPSTDMNLRPVPGNSGLGRTYMWYLGETPLPYGFGLHYTTFDVKLKALQEPAITTTNQLTLLEDSGAASGVPSWQKTLERPMLTIAVTVTNIGEVASDYVALLFLKSDVGPQPRPLKTLAGYTRFRSIQPGQAAVKEVVVTVERLVRVDELGNRVLHPGSYEVFVDLDKKAVHKFHVGGPAVVVEEFPQPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD49</accession>
    <name>A0AAD8XD49_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_723586</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359470.1">
        <property type="nucleotide sequence ID" value="XM_060512577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD49"/>
    <dbReference type="GeneID" id="85396475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="28"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1712613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="24451" checksum="0299594A272A6C36" modified="2024-05-29" version="1">MAPKVLIVLTSVDKTEKSGKPIGWYLPELAHPFDVLKEAGVEMTFASPKGGVAPLDQASVEMFARDPSSKNFLENHKAIWENTEKLSNFVGRASEFDAIFYPGGHGPMYDLAFDATSHALIAEFAAQNKPVASVCHGPAAIVNAKLNDGTYLIAGKTVTGFSNTEEDQAGFTPEMNFMLEDRLKENGGKYELAAEPWGEKVVVDGIVITGQNPASAHGVGKAIAKALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD54</accession>
    <name>A0AAD8XD54_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_538318</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361931.1">
        <property type="nucleotide sequence ID" value="XM_060503376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD54"/>
    <dbReference type="GeneID" id="85387275"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="117" mass="13588" checksum="7D53F693E3BF2AB5" modified="2024-05-29" version="1" fragment="single">TPAAAGIDISRLRFECRWQNCGKVFRRPSDLTKHERYHIKEYLCDEANCDKAFATMKDLKRHKKTHETLDGDGAGGGYRCRVPGCRKAKTGHVYNRRDNFVRHLRTKHVGMDIDVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDD2</accession>
    <name>A0AAD8XDD2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_387687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363639.1">
        <property type="nucleotide sequence ID" value="XM_060502755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDD2"/>
    <dbReference type="GeneID" id="85386654"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF82">
        <property type="entry name" value="FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="581" mass="64575" checksum="D45FDB2FA3F84601" modified="2024-05-29" version="1">MDAFDFGQLSVSGRKIIVGIDFGTTYSGVAWAETQRPDRRTAITTWPISKTIREGESSDKVPTKLRYAGDEVQWGFSIPVTAPQDEVVEWFKLDLDPSLQSMGQAVSSEARGGRNVDKLVTDYISALGDHLVYTLKEKLGEQVVNTTPLEFVVTVPAIWSDLAKDKTKQACQKAAGLNTVTNAVAPIHLVSEPEAAAIYALHGLDPHGLKVDDTVVVVDAGGGTVDLISYTITSLKPILEVQEAAPGSGALCGSTFLNMRFAKFLKAKLGKEDGFDDEIMAEAMEQFEKKVKRQFTLGAAPDDTYTIPVGGLANNKELGINRGRFALKASDLQTIFEPVVLECIKLVKDQITASNVPIRAILLVGGFGASNYLKERLRNAIDKSIQIMQPPNAWQAVVQGAVMKGLAQVSPDKLTQVKVQNRKARKHYGTEWRSKYDAKLHKHLEQKRHWCGLDGCYKVYTMEWFIQRGDNVSENEPFYTSFVWTGLVSQGRIKKIKMDIYADRNQRIAPVARDENVAMLVHVEADVGHIPEHMLSRRQGLDGQWYYELNCKIEAVYLSASTTYTLLYNNQRYNTVTAEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE93</accession>
    <name>A0AAD8XE93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_743273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361583.1">
        <property type="nucleotide sequence ID" value="XM_060513135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE93"/>
    <dbReference type="GeneID" id="85397033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36625" checksum="19D90A53A2B6D318" modified="2024-05-29" version="1">MSSPIGEVEAQPVQPAAASTANAPSASADIEVDSEVRNDASTMDDRMSSYTASLSSSVVDYPTEYGRTYHAFRAGSYNFPNDERESDRLDLTHTVMVKTIGNKLFLAPIDEAKTHRILDIGTGTGIWAIEVGDFFPNAEVTGIDLSPIQPPWVPPNVKFEVDDVESPWVGNKKYNFIFSRYMAGSIADWQLYISRIFENLTPGGWAEFQDWSLMLDSDDGSLNNTQTHRWATLFMEACANLGRDGAPGPSLNSWVKDQGFQNDIGMCNLIQMLEGLDAFTLKLFCTALDWTREGALVLLSQVRQEMKACKSHVYLHFHMVYGQKPEPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEZ0</accession>
    <name>A0AAD8XEZ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_654076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362318.1">
        <property type="nucleotide sequence ID" value="XM_060510690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEZ0"/>
    <dbReference type="GeneID" id="85394589"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="214" mass="24195" checksum="EC9343451D4E978A" modified="2024-05-29" version="1">MDQARATVEYLPPPTEVFRILQESGDRIPIFRSEGVIACGQPRASARKNTTVQDLEGLLSKFEGCKSSPLSRSCVYAYRRFRVTTNKLSGIAGNMVDYIPYEQALCGSGNLSDLEPNMNQQIWTYGHRRQPHRPTDGRQSLQIKNSTHHRRLQKAVTDLKAILLGDFVLLMESLGYETKLDVIKQRWRLVGWVVSAHILCHLHGPIEIPISSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFU3</accession>
    <name>A0AAD8XFU3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CPL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_718938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365827.1">
        <property type="nucleotide sequence ID" value="XM_060512128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFU3"/>
    <dbReference type="GeneID" id="85396026"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CPL" evidence="5">
        <location>
            <begin position="433"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="640"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="641"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="694" mass="76594" checksum="E548AC0F1043B52D" modified="2024-05-29" version="1">MASTGVKRKSAPAAGKGVADGKFNKKAKVESKKKAQPVETPEEDDEGSFEDDSEDSDDGGVQLTPRDRAQQAQAKGKKDGANGADKNKNFERGQNSRESHAIQKKLALERKMAKPLADELARTKKIWERKSHVPSEERKQLVDELFTIITGRVKEFVLKHDATRAVQTALKYATATQRKQITRELQGTYTQLAESRYAKFLIAKMVVQADGEIKDLIIPEFYGKLINHPEASWILDDIYRQIATKEQKAILLREWYGPEFALLERSKDEKPTSDLATILEQNPSKKAYILKSLNDMINSLVQKKMTGFTMLHDAMLQYFLNVEPGTENFNLFVEMIKDDEEGDLLKNMAFTRSGSRLVALLLAHGSSKDRRNLLKAYKDNFVLMSGDPNAHIVILTAFDVIDDTKMSSKAIFPELIGDDKEKATDNIVVSTSNPFAKATLLYLLEGQTRALFSDNMSDDLAILKEVHAIRQTTSKKDAEIRRKELIAVMSPALITAVVEAAPVLVADPFGCQLVADVLLSAEGDKTAALEAVAAVAEGDPSAEPMEVEGAPTPVHVSRTAFGGRLIKTLIAGGKFNKETGKVESVEPPLKFADVLYPIIKDYIVDWATGPSSFVVLNMLEAEDFSHAAELKKTLKKHKKDLQKAATEETAEQKEAKEARAQKDGEKGAKKGKKGAKKADKPVGNLGSKLLLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG31</accession>
    <name>A0AAD8XG31_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364991.1">
        <property type="nucleotide sequence ID" value="XM_060514151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG31"/>
    <dbReference type="GeneID" id="85398049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="22799" checksum="DBDEA454FCFA1115" modified="2024-05-29" version="1">MDDKGPFPWPDPHAQVSFSGSESERTMAASRAPSEMGASSTLPMDIDIQQSQIRRRTISCRHFYFPTPQEEHEAEHHKQPQDTAKEVATYIVKNIAPEKRADAVKTVARALALRRLKEQAQLQIQREKEKQAEENDQMTISKSAFKLHMARIKAAQEISASWMKDTEDSLEAESIQARIIDMALEEMHDTAMALEKGKGPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG36</accession>
    <name>A0AAD8XG36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_577485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365006.1">
        <property type="nucleotide sequence ID" value="XM_060505024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG36"/>
    <dbReference type="GeneID" id="85388923"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1251" mass="137271" checksum="3D4A4CF40C38A507" modified="2024-05-29" version="1" fragment="single">NNGSSSVCPCACGKTTWVPTTYTEVYTLYDSTNSDGPIVTAPSATMSDSSALSGFFSSIASDDDDDDGDHGGDDDDDDGGGDDDDHGGDDDDGGDDDHGGDDDDDGGDDDHGGDDDDHGGDDDHGGDDGHGSDDDDRGHTSDDDDENSLFDFRIDLGIDILNKARNILGHGMDIGFGTNKPAGKTEPDEPEPSQSEKETSTSTSTSSCTQTYTIAPHCTQPCVVSQIRSQGTSSFTTSCATATCRTTQLCTSIETTTTTTYTTKKPKPTAGCMAGKCLSCQDDNKKLEARQGWWDEDILTETISEPEEWHEGEYEWWEKMRRVAKYYGPGLAMGSKTGHDSSASWEAFGPTPHGGGAGPVWGCTIIASFSPEGVYANHLWEIPNFNIPPDEEKYFKVEKGYREPYYFEQNVNRFLQYGSLDTPKQKEYPALCPMNLPGGPLYGDDYQFFRTIMFVPIETTGKMYYAHQNSLIMSILTEQCKIDKKYITIYGYEPKEVLDKDFQYDLGRATPPADRRASNPWDGLFSWQYTPKGSSGKKELVVRFEKSIIHRDAWCGDGLVTQPEAPVRFDLRPNTPRPSDTGTPRPPAKKLKLRQDEGTCPHMIACGLGSPKLSVCDYKKFPPPPLEGPSRLKSRAPPSNDPAKGPIQAELDLESETMIEPEDSIGGERWWYTRMRHAIWSTSSMVRFNQEVDGTYTNRPRFGGSGPIWGCTVVVVASPAGVWTSHMWEIPTFSLGAEFGSGDTTEWARVYPKSQIEYFGEGVVDFLSWGNNRGSYRQLKNGKVPTRNPGFVEFAAKNSGEPFDVKTKTWLWAGIITRAHKDMRGPSLQYQDSAMRTAYSWQVERIQNILRQKLGINDKDFVKIITYAPRPNMAQRNPDMQPEYGLVNWQYHPSHVEEGKKYSERKLRIRFEKHVIFEKTWCGSGNKIIIADGSTKPPPPPPPSKHRRQEDEGGEVEACLLAHNSSSAAASASSVAASAASVLPRPTQACTADAECGSLACPQPRFGACLYGACRCVLSESLGYTKTPATPHCSSLSCGSNQTYACITKGANPKPTCRCVNRPKLFEPCAAAADCEHLKCDANHFSTCRPLINFPGADSICQCEALALKPGAFCTVDSHCDGLPCDGTKNRRGKCIKPTSDDTGGVGLSGGCQCDYYQSEGVGCASHDDCSTIRCNEDKPYNALDCAGKGNLLCGEKSMCECKPCTENWKGLTCQVDADCNHCCKRGTLPKCKYTRLEFWSGNECQCDLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG77</accession>
    <name>A0AAD8XG77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NmrA-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_625647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363683.1">
        <property type="nucleotide sequence ID" value="XM_060508504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG77"/>
    <dbReference type="GeneID" id="85392403"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="36455" checksum="E0D7DC014E4326EE" modified="2024-05-29" version="1">MVRIAIAGGSGNVGREILDALVARGKHEILILSRKDDPANDFGSGVKWVKTSYNDVAQLAQVLEGVHTVLSFVAGPVDPTNVAQRDTQKNLIDASIKAGVRRFAPSEWASSKLEHMFWYGFKEETRKYLARINKDKKVLEYCLFQPGLFTNYMTYPFNSSKHVQLFETPFNFYQRRALVIDGGEEAIITFTTAQDLARVVALAVEYEGEWPLIGGVQGAQVSVRQLIALGEKIRGGPFDVTKLKSDDLKAGVVNAPWLPKVEHPSIPPETLGAVASSLLSGFLQGIVAGNLECSDEWNRLLPGYEFTQPEDFLPTAWAEINAGATTVFTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGA4</accession>
    <name>A0AAD8XGA4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362455.1">
        <property type="nucleotide sequence ID" value="XM_060514476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGA4"/>
    <dbReference type="GeneID" id="85398374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524:SF1">
        <property type="entry name" value="MRH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="582" mass="61846" checksum="9CC2E7F2D3ECEA95" modified="2024-05-29" version="1">MAILSRYLPFSEATTTLQAVTYLLGISLFSISFLVFLNSSISFVITDLIGVKDGVGDIVGTLGFVDELVALVACPVWGLVSDRLGVRWVAVIGYAVIGAALLLFVQAKNVYPQLLLARIFFAIGATASATMVTAILPSLTDDGDNSDSSADAANKPTHNPRNSVAMSLESDMTITPARFHGFGGDGQTATAGEREEAKAGRPSSLAGYVGLFTGCGALVALSLFLPLPARFGEIDGITPATAVADSFYVVGIVAFVISVFVFFGLRNLKGEEGKGWSVLLGLKTNSDSEDESDESGSDHPTRPKVLPYFRLLRDSVTLGFTDSQIALGYLGGFVARASTVAISLFIPLYINTYYISNGFCQGSPHDPSPELKKECRAAYLLSSILTGVAQLFGLFAAPAFGYFNRRRGRINYPILLATAFGIIGYIILPQLQSPEYKNVDGRGGSPAIFLIVILIGISQIGAIVCSLGFLGRGVLTADIPKSQVIDTVEDSAEAMETSPESAPLLQHNASVDAVSRVRLKGSIAGMYSWFGGAAILLLTKLGGYLFDTVSNGAPFYMMASFNAILFFASLGIDAARFYRDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGK5</accession>
    <name>A0AAD8XGK5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_649781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367254.1">
        <property type="nucleotide sequence ID" value="XM_060510312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGK5"/>
    <dbReference type="GeneID" id="85394211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000233">
        <property type="entry name" value="Meiosis induction protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000314">
        <property type="entry name" value="Serine threonine-protein kinase mak"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="539"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="617"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="680"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="719"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="768" mass="84762" checksum="1780AEDFB55B77A8" modified="2024-05-29" version="1">MTVAHELAHRGSSSHSANNMALEDRFEVLKEIGDGSFGSVVLARVRSAGASVARRGTVVAIKTMKKTFESFTPCLELREVVFLKTLPNHAHLVPALDIFLDPYTKKLHIAMEYMEGNLYQLMKARDHKCLDNASVKSILFQIMQGLEHIHAHHFFHRDIKPENILVSTSSHQDTVTSFRRYSALVTPPSTPPNYTVKIADFGLARETHSKLPYTTYVSTRWYRAPEVLLRAGEYSAPVDIWAVGAMAVEIATLKPLFPGGNEVDQVWRVCEIMGSPGNWYNKSGARVGGGEWKDGTRLAGKLGFSFPKMAPHAMDTILQQPQWPASLSHFVTWCLMWDPKTRPTSTQAIAHEYFVDAVDPLRPKSSASRILGRKQSDLGRGNNSNSSTPTSTKPSWFRKSLIGRSESAEVAVPQSISKESTPRPSPVPSQTTNEVPVAKTRPAQSKRTTWTNGPSNARNGVTYNDSYANGRQRTVQIDEKKKIGRQLSVASSTNNYAEIHRQQAERALNGNSGLASPPGGHKESFFSHLRKRARRFSGRHQAPMSPNSDDVEAQAGCGPWNSNRSSMVIDNNAPTPPPKPTELYEPLDKALRDVQQNHDNAPVPPAHLITPSSTLKRHHSLPQHHPRSVDNLMGAAKGTGPISSRTRRAHAHGVQHYDAPDEEDELLDEVLNSTHRAMKRLEKDGKPGLRQSASNIGISNPYPTPSPSANGNNSVLFGDNHEAVAPKPLDLKKSHGAESQYKWPTPPYEESEWAASASASIWAASNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGL8</accession>
    <name>A0AAD8XGL8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_616033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366547.1">
        <property type="nucleotide sequence ID" value="XM_060507945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGL8"/>
    <dbReference type="GeneID" id="85391844"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="75" mass="8816" checksum="55786E825E5DDB99" modified="2024-05-29" version="1">MRFAVSLLRRIDLFRLSVNISRLQCPIVLLAYLLPELNAKLFLQLEPKRRKSGSRWQLLRAYVQTNFADSSVKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGY2</accession>
    <name>A0AAD8XGY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_410192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363025.1">
        <property type="nucleotide sequence ID" value="XM_060502909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGY2"/>
    <dbReference type="GeneID" id="85386808"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="715" mass="76005" checksum="98B488942D92E480" modified="2024-05-29" version="1">MPPKKDNGTAPPKSWIPPSGYTRRQTRNQQQQPNLWQGLTDRGEAYDTQGNHVLVRPVRQRRRGQQTAAPPPAPPQAPAPPAPPPPTAPVLPPMPSPRNADSGDESDDDPGGEPGTKPDDGSNDEPNKTAEPETDGGAGDEPNNESGEEPEAGSGDESEEESRAGSGDESGNESGDEAETESGNGPGDGTSIGSGDESEAESGDESAEEPEAESDNESGDDTAGPSSALTPPKRPTRTPLPTERPTKIKIKLKTTKTRTATAAESLDGTDSNDSDSPVGPSAGESDSDSPGDGSDGESSKKKKTNKGKQNATQNNAETDSDPEAPEESSEPEEPEDDASRDDNEEQTDNSQRSEGSDLEGPQDSDQGTPDEATPSRRSAPGSVGGDSEQMFTPSKTPQERKGSKNEDPIQMGSDESESSEVFRDPRSEESQGEDEPHQRTIVHYGSDDETEMLVHERPDPDHTFDNGENTLNLEDYLSSVGGDPDWRGEYDGSEDDGDNRYDQSSNVGGDYEGNQDDDDDSEMHLPDYTMFEPDETEGQPEMGRGQGSESNLPRQSSPSSVSPSFPRSNRSPSHSPDPFAGGQQQPSSSSGGQGSIAQGSKNGQSSGSKTGSATGSGNGLVAMKAKNVAGKRGRSEEHTKDDEARPQKRQREDSGKTAVPTARNKFPRTQYRQICPYPSPRDLHSQTSDKWATAKRPGSSLEEAVVKPAKKTKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH37</accession>
    <name>A0AAD8XH37_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_270786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366116.1">
        <property type="nucleotide sequence ID" value="XM_060502053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH37"/>
    <dbReference type="GeneID" id="85385952"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="129" mass="14507" checksum="1880507D12AEE15D" modified="2024-05-29" version="1">MTTSLTDYQCQALSATDSIRLFSISRDDSYPHGLCLSLKEVNLDDEPVFAALSYTWQLPKYSNIQDAQEPGPGRTFEVICDGKVMQISENVFDFLRTILDFRCRSTDQSSSATRKCPPKVRSALDTMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH99</accession>
    <name>A0AAD8XH99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_621862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364823.1">
        <property type="nucleotide sequence ID" value="XM_060508293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH99"/>
    <dbReference type="GeneID" id="85392192"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="42998" checksum="BFCD3C935A5C6C0E" modified="2024-05-29" version="1">MASVGLGEPVEWFDLRELRQPCKYDQETASHVKKGQDPGPQNYKRNHGSVLQGKKEFPNTDTTMETSPQPSNPPRKRDFKRRFTDLHIDITSILHGYTPSPHFLASDVTGFILFTLLATDWPSVWRAKLFRAFPLAQTAPETLSGFWNAFWQERWHQEDHAESKTDKWNPGLYKSPPPRMRSCREVLNRQQALRNCCAAQMEELDGPEVGKELLLQVALAFCWLWAVIKDYKRLLCLVHAIETDGEGCRREEFEREVPVVVCKGEGTMLVARGGPSYCCLRRLQRHIDRGQSMIDKFVELEMCDGTDDALWTELEWLSEKEGEIPAEMPQKDRFLVNRVVFSAGLSWLMVAISCDFATFYFLVLIRQLGARSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHA9</accession>
    <name>A0AAD8XHA9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_393275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363370.1">
        <property type="nucleotide sequence ID" value="XM_060502804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHA9"/>
    <dbReference type="GeneID" id="85386703"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000365">
        <property type="entry name" value="Start control protein cdc10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0183">Conidiation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0749">Sporulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="9">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="626"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="445"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="637"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1723315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="763" mass="82721" checksum="6BA4AD0BF848D293" modified="2024-05-29" version="1">MEVNGVAVMRRRQDSWLNATQILKVAGVDKGKRTKILEKEIQTGEHEKVQGGYGKYQGTWIKFDRGVEVCRQYGVEEVLRPLLTYDMGQDGGVAGRGDFNTPTKEQAMAAQRKRMYNAGNEARTNAMAGLNGTFFKNISSTASHAVAAISKARFDSPGPRSRNGPTKAPSFSRQSSMQNGDDFPGNSQQSFASDYGNQNDSAYSTQQTSQQFDGPEPPRKRQRVTMTPQDSFGYNNNSMEMYQNQFPGSPTEPNESFIYSQANVPPHDGHSPLSPLPFEMSPDAEAKRSMLMSLFMDSATSDQSKHEMLRTLAPIELDMPIDQQSHTALHWAATLSRMSLLRALIAAGASPFRVNASGETALVRACVVTNSMDLGQFPDLLDVLGSTIEVRDSKGRTVLHHIAMTSAVKGRNAASRYYLESLLEWVVRQGSNPNGQLTANGKGESAPASSQSQPSSQPKMGIARFMSEIVNAQDHAGDTALNIAARIGNRSIISQLLEVGADGEIANRAGLRPVDFGIGGEPADETSKIINGANGNATNGDVEKNGLVSSEPTKESSDDIISSITHLLTEASSTFQSEVKSKQAVIESLHTTLRTTSAQLGEAKRNLEAMQATLRKQQLARQKVSNLSHAREEEQVRLTQEQNRAGRTNALSSSWETELSAALETAGTNGEGGLLPSAATLKARLSAVSARRDVTRKMAGALKGRSKDLEVKYRRVVAMCTGEPEDQVDAVVDGLLRAVESEKGELEVERVRRFLGGVEGVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHE7</accession>
    <name>A0AAD8XHE7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_750986</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366446.1">
        <property type="nucleotide sequence ID" value="XM_060513989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHE7"/>
    <dbReference type="GeneID" id="85397887"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042224736" evidence="6">
        <location>
            <begin position="19"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="115"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="63849" checksum="849C0DADCC2B9B44" modified="2024-05-29" version="1">MFIRYLPITLLLSSIVSADSICKATPYDTTWPRDSDWTALNQSVGGTLIKTRPVASSCYDGNPFSSALTCDTVDVGLSSSAFHAALPESIDYPFWANNSCVPPSDYAYKNDGCKLGGLPEFILNATTAEQVATAVKWASARNIRIIAKGTGHDLNGRSSGAYSLSIWTHQLRSIKLDRRWPRPSTNITEKVAILGSGNNWGRALEATAATGRILVSGQVKTVGLGGFIGGGGHGPLSSHYGLAADQVLQATVVTTAGDILVANEAQNQDLLWAIRGGGPGLYGIVTEFVLRTHPIPSNVVQTTLSLSMTGNDTGSSAAASWDAMALLSSALPDLMDAGVAGFGNAATLNVSPKSSSGVIQGIGATFTFFGYNTTASDLVSLLNPIRARILQSENGTLSVVIAEPTVFPTYLSFVDALNGPATPVAQISLISSRLLGRSELTEIPLEKLRAHLQEITKSQVEGGTAALVYGLQGGLGPRQVEASMRGAVTPAWRSAYIHLISSGTYINTTNTTPQDALVTAAAWAEENKEAVWRKWAPGTGAYINEANPFNSNFQEDFYGGNYDRLLEIKDKYDPTASLYIRSGVGSHKWDYNSTTGKLCHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ55</accession>
    <name>A0AAD8XJ55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol-specific phospholipase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_718998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365695.1">
        <property type="nucleotide sequence ID" value="XM_060512135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ55"/>
    <dbReference type="GeneID" id="85396033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08586">
        <property type="entry name" value="PI-PLCc_BcPLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="1">
        <location>
            <begin position="154"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="471" mass="52435" checksum="C9C31D1DF1DBC05B" modified="2024-05-29" version="1">MTNITIRNLTALPATLKRVERFEGERKRTGDFLGNTFGTIGSFMNATNFTTKETHAKGDAHQTEDVDVHVEPFAISGTEIGAPDIGNHDVVRLQFEIEGHRYEIDAPSPTNRSSVMKKLDDAPLELTAVYVANGAFLAIMSSANLNAWMHELRDEYPLPLLSIPGTHNSPTCYTALPSVRCQAVGVREQLDNGVRFLDIRVSVSQDNDDLALVHSAFPISLTGNKYFADMLSDIYAYLDANPSETVLMSVKREGTGKGNDEQLSRYLRDRYVGRDAHRWFIEPRIPHLGDCRGRIVLIRRFGLDEPLRGEHDGRGWAIDAQNWPDNCEDGTVGGGLIRVQDFYEIDQSTNVEKKINFSHGQLERAAEQLFHLPGMPDFNADAPPLPFFVNFLSASNFFNATCWPERIAAKVNPAVIEYLCIRHGEPGKGPHQLNVGDAATGIIVTDWVGAHGDWDLIRCIVGMNARLQLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJA1</accession>
    <name>A0AAD8XJA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_575386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366100.1">
        <property type="nucleotide sequence ID" value="XM_060504808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJA1"/>
    <dbReference type="GeneID" id="85388707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22922" checksum="34E2B400ED4A353A" modified="2024-05-29" version="1">MSAPPAGGVTERMIIPVKGTKEDWKEPLKTYLLALKTQDGYLRTRWGPWSENEQVLDLISGWKSKESRDSFFASSECAKAMEEFKTVMTGPVKSYFIKFVPYAPRAAIDSPIAETITISGSTMSEDDMRAQFEKVRGMDGFNDFASGFSTEEVDGGGKVFVAALGWESLEKSRAADKSVYIPASGKVESHHVNFHYPIKGFSVTNTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJT9</accession>
    <name>A0AAD8XJT9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein L34e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_717700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367675.1">
        <property type="nucleotide sequence ID" value="XM_060511978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJT9"/>
    <dbReference type="GeneID" id="85395876"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="116" mass="13109" checksum="FDDEB902880E5208" modified="2024-05-29" version="1">MAGNRVQYRRRNGYNTSSNLTRIVKTPGGELRILHIKKRGTAPKCGDCGVKLPGVPALRPREYSQISKPKKTVQRAYGGSRCGNCVRDRIVRAFLIEEQKIVKKVLKEQSQSEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJU9</accession>
    <name>A0AAD8XJU9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_188735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367825.1">
        <property type="nucleotide sequence ID" value="XM_060501578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJU9"/>
    <dbReference type="GeneID" id="85385477"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="164" mass="18491" checksum="1FDFA9FA73C39281" modified="2024-05-29" version="1">MPAKIAQQLVICRTCKVCRSRKVKCDGQRPECSGCRMRSHRCEYPEDGRKAAVRSKESEIQSLQSQIEQLKPQVSERSPSTGIDSCLQTRPLLLFLHSSGMYVLRDLRLAGIRQTPIFPCLSYTSALPLRATRPCMVPPVFFMMMPAVISGRVQRQAKTRSMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJX9</accession>
    <name>A0AAD8XJX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome c oxidase-assembly factor COX23, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_749236</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of cytochrome c oxidase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the COX23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368275.1">
        <property type="nucleotide sequence ID" value="XM_060513738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJX9"/>
    <dbReference type="GeneID" id="85397636"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033108">
        <property type="term" value="P:mitochondrial respiratory chain complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051040">
        <property type="entry name" value="COX23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46811:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="8">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="10203" checksum="BA51081F1B507495" modified="2024-05-29" version="1">MSEPQKPETAAPEKVDETYTESKAKFEGKAKSEYFDPCQELAQKSIKCLHRNGGDRTMCGDYFQAYRDCKKAWFDKLKADRKAQGAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK97</accession>
    <name>A0AAD8XK97_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_569291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368970.1">
        <property type="nucleotide sequence ID" value="XM_060504175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK97"/>
    <dbReference type="GeneID" id="85388074"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="4"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="371" mass="40378" checksum="CD489990BAA91CE8" modified="2024-05-29" version="1">MVKTVVVLGAAYGGLAVAHRLLKYTRQTEPDLRVILVSKTTHFYWNMGSVRAIVPGIVKDDQIFQPIEPGFASYPKESFEFVLGTATGLDMARQSALVSTASGPRSLPYDYLVLATGARAASPDMPWKSSNSHEDTLRLLHATAEKVKTANHIVVAGAGPTGVEVAAEIRFEFKDKEVHLLAAEDEILAGDSIAKPVENEITRLGVQLRKHARVANSRPLPDGKTEVKLMSGEVIRTDLYLPTMGLVPNTEYLDPGMLNERKYVNVDEYMRVKGVENVWACGDIVSFPRAGFMLTDKQAAGVAKNIELAIKGKEQAVVKGMPVDVYVCATGRSRGAGRIGWVKAPSLMIWAVKSRNLGMPMAVPYANGGQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKZ3</accession>
    <name>A0AAD8XKZ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH:flavin oxidoreductase/NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369337.1">
        <property type="nucleotide sequence ID" value="XM_060513606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKZ3"/>
    <dbReference type="GeneID" id="85397504"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF2">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE PYRROLE 2,3-DIOXYGENASE (AFU_ORTHOLOGUE AFUA_5G01450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="46982" checksum="B50E42A05C2D827B" modified="2024-05-29" version="1">MTGTANKAAPGVPFYTPAQEPPAGTPVDAPAAPTLFQPLQIRDLTLNNRIWVSPMCQYSADNGHMTDYHLVHLGQFALHGAALTIIEATGVEARGRISPEDVGLWQDSQVAPLKRVVDFIHSQNQAAGIQLAHAGRKASTLAPWITETKGKALALESEGGWPGDCVAPSSIPFTEGWATPRELTVEEIQGVVKAFAESAKRAVEAGVDVIEIHGAHGYLITEFLSPLSNQRTDQYGGSFENRTRILFEVIKAVRDVIPSGMPLFLRISATEWMEYDGKPSWMVEDSIKLAKLLPEAGVDLLDVSSGGNNEAQKIEISPYYQVSIAGKIREALAAEGKKLFIGAVGMISSGEMARSIVQAQGSGSAEANGHNGVDQGNAATLEVDEEHGQVTQADAVFVARQFLREPNFVYKIADEIGVRIKWSNQYHRAPRRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL30</accession>
    <name>A0AAD8XL30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369358.1">
        <property type="nucleotide sequence ID" value="XM_060510130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL30"/>
    <dbReference type="GeneID" id="85394029"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052897">
        <property type="entry name" value="Sec-Metab_Biosynth_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37017:SF11">
        <property type="entry name" value="ESTERASE_LIPASE_THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="254" mass="27260" checksum="CEA1B27DFEA3D8A3" modified="2024-05-29" version="1">MSSRTPPTFLLVPGAWHRPWSFDLLRDDLHGRGFSTETVTLAGVGSTDANVGLEQDTAAVRTELQKLVDDGREVVVVAHSYGGVPTANAVEGFNYKARVAQSKTGGVLMVVYMASFAIGAGSALSDGAGSVPWWDVKDGFISPLYPISVFYADVEPGLATKAVEALRPQPFKTFQDKSGFEPWNEGFEMGYIFAENDQAIPLDLQIMMASQFSPSSFTDSLSASHSPFLSMPKDLGDALQQAAKTAVAKTEGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN04</accession>
    <name>A0AAD8XN04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_566979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370406.1">
        <property type="nucleotide sequence ID" value="XM_060503907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN04"/>
    <dbReference type="GeneID" id="85387806"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="10"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="341" mass="37448" checksum="25B18BD0C51EEEF3" modified="2024-05-29" version="1">MVRLSGKSLFHLPADYAVGSLIVPTCFRATAQYLAQYGPVTRGVFRIPGSLRVVNAIFDYYCYEKPGEEVTSTIRCPTLPSHINAGAQDVASAFKRLLSVLPGGILGSLTLFDALVAIHSQLRGEPELSRTKESKLRARLIAMAIGTIKSHFRRELICAVFGLLSLIGRAAETAAREDEQGRPLPTSDLMGYAALGIVFGPLLVGNLLDSYTMKLANPSSGLLLFPLTPPRLKRERQRKNTVQDNTDSMSVDKIRVANDITEMLTSNWREVVRNMKGLSSFRGPNEDLESTSRRRFLRSSNSDSLAVGLPKGWRSKHSSPRSSINQHRSKSPITPTPAPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNA3</accession>
    <name>A0AAD8XNA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_715575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370556.1">
        <property type="nucleotide sequence ID" value="XM_060511761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNA3"/>
    <dbReference type="GeneID" id="85395659"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="22"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="53811" checksum="61FA5C66B2F53291" modified="2024-05-29" version="1">MVQKTVIGAALAQAASAALYDTTVQTKYGMIQGYPAFNSSPANMSLDNWADIAVWKGIPFAASTAGNNRFKAPQPIVAWNSTLDAKSFGSICPSAVGSGTDAYTVGEDCLNLNVWSAANSTDAKLPVVMWSYPAGSTAAMPLFDGAGIADKGVVYVNYNYRTGSFGWLATPELNQERLSTAGSNSSGNYGMLDQFAALKWIHENIASFGGDPNHITVMGQSAGSAATYHMLNGPLHGVPLHGAIIQSGTASRYMASMNCSDIACMRALPMEDLVTEFLNSEFDFTATLDYYAMPDTYINTLEKGIAQDVPVMTGNTKDESGAEYGLNITLSTYISDFNETFNTWKDKFLAAYPANDSATASAAENAQWTDRSKVGTFFWSQLWQANATSSIYNYIWDHAPPGQTQGAFHMSEINYVHNNLYVTDSPWTSEDYEIAEIMNSYWVNFIKTGDPNGDGLNQWTPASNASATVMELGDALPIAKDNQIELFAQWSDTLVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPT1</accession>
    <name>A0AAD8XPT1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_242162</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371251.1">
        <property type="nucleotide sequence ID" value="XM_060501876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPT1"/>
    <dbReference type="GeneID" id="85385775"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="122"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="416"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="480" mass="53594" checksum="BA2BAFCDBD39E85F" modified="2024-05-29" version="1">MTSNAKSRWADSAEDAALDAKLKREKEEKKRLKAEKARKAAEAERLAQQARAAKNSNGAENDGEGDDSTRPAKRRKFTPDAEDRTTTADGDGGAPLDVKEGAAKLMRFPVGHWGKCRSVENYDKLNDIEEGTYGWVSRAKEASSGKVVALKRLKIEPSDRNGLPVTGLREIQILRDCNHRNIVNLEEVVVGDDTSKIENIFLVLEFVEHDLKSILEDMPEPFLLSEVKTLLRQLTAGVAYLHDNWILHRDLKTSNLLLNNRGQLKIADFGMARYVGDPAPKLTQLVVTLWYRSPELLLGARAYGKAVDIWSVGCIFGELLTREPLLQGTNEVDQVTKIFELCGVPTQETWPSFRSLPNARSLRFPKTPNATGSMIRTKFTTLTNAGCKLLNDLLSLNPDSRPSAKEMLEHKYFREDPKPKKEGMFPTFPSKAGQEKRRRHEPNAPVRGQNAADLGDVDFSGIFQGRDKEEKGGGFSLRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQC6</accession>
    <name>A0AAD8XQC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_160430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371521.1">
        <property type="nucleotide sequence ID" value="XM_060501394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQC6"/>
    <dbReference type="GeneID" id="85385293"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="250" mass="28101" checksum="02B1FF4027E27506" modified="2024-05-29" version="1">MAYPIRISVLNRRKEQPLHPASSRLIPAWWNHRYPHVPRTQSGEGGAAWTRKWTDPDRGGRQARYVLDSPTFSIGFRWRRFPLKIARRRSPISSSSATYTPTYLTFTTTPHIKSHSSTHHSDQTHIPYTSTHIHTHPPTYLYPDRLLGPASYHSFTSRSRHYRLITDSQPPLSSPPPLLSAALPYLSTPYILYTPHPAGATNRRAPPPPPTVSPSSSAGIHTSLPPSHDAHLLTRPGSLKPNPVHLIQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYQ5</accession>
    <name>A0AAD9CYQ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dicer-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_763793</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="16 17">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368942.1">
        <property type="nucleotide sequence ID" value="XM_060515220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399118"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050688">
        <property type="term" value="P:regulation of defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000015">
        <property type="entry name" value="Dicer-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056755">
        <property type="entry name" value="DSRM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF62">
        <property type="entry name" value="DICER-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24995">
        <property type="entry name" value="DSRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0930">Antiviral protein</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="96"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="22">
        <location>
            <begin position="385"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="23">
        <location>
            <begin position="584"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="PAZ" evidence="20">
        <location>
            <begin position="834"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="1027"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="19">
        <location>
            <begin position="1189"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00035116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1728887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1474" mass="168156" checksum="857D2F6652F6F53D" modified="2024-05-29" version="1">METSKHGVDEQDQAEEDDDEDDYRRWSVNPERPRKISEKKRQDHAKFQSWIESNQAKVLEAASKTKAPTHGSVAHLVKESENRRIIQTPREYQIELFERAKQKNIIAVLDTGTGKTLIAALLLRHILEKEVEDRAVGKPKRTAFFLVDKVSLHAVLECNLEHTVARYCGDMMWSSEFWAKQFEENMVVVCTAAILQKCLMHSYIRMDQINLLIFDEAHHTKKNHPYARIIKDFYIKESDKEKRPKILGMTASPTNMKVATAQLDEIATVSEESLSLNPNKRKITEREIHYTPLMRSFESELVQKIRALLFEKELQWTTTAMAELGPWVADRFWKLYLTDNTIARLANRTDINYSGFDAAVQKLRDIIQSHNFKPPTLSLDDVSSKVLRLWDELKVRFSQPTDYRCIVFVEMRLTAVLLAELFRQDGMDLPHLKPAALVGSQSSAGLANMSFKEQLLAITKFRRGEVNCIFSTQVAEEGIDIPACNVVMRFDLYKSVIQYIQSKGRARQQDSEYLSFVEIGNGRHTRAIAQATYDQSVLRRFCSALPEDKKVMGMDINATILQGELHYQTYTIKETGAKLTWMSSLEVLANFASSLRQSSDEVLMPEYVVTNQGQSFIAEVQLPAQSPILSMTGMPHKRKQSARCSAAFELCKELIRKKYIDLNLQPIFTKKLPAMRNARLAISANKKAEYKMRTKPEIWSRVGAFDQLFVTVLVLGSPDAVGKDKVSKPLLLLTREKLPDLPPIPLFFGNDQQSDAFAVSLPKPINISSADSELLKTFTLRVFKDVFSKEYEAMVCDMPYLLAPTTQSHFVDYQHADAATLIDWNHLQATKDKEYLDWDNSTSDEFFTNKLVVDPCAGSRKLRLRGVRKDLKPMDPVPEGVPDPCHRPWRDLAVEKNIKEYSVSLWMKSRLKRTWRDTQPVVEAEVISLRRNLLDDFVEVTNEGSKVCYVILEPLRVSTLPMETVVMAFTFPAIIHRMDQVMVALDLCKLLKLDIRPDLALEAVTKDSDNSDEHDAEKINFQGGMGNNYERLEFIGDTCLKMATTIALFTNNPDSNEFQYHVERMLLISNRNLLNKAIDRKLQEYVRSKSFNRRSWYPQGLRLIRGKEGIVDAKHALADKSIADVCEALIGAAYLTFSDSNNFDMAIRAVSAMVNDKNQRMTSWADYYAEYKPPSWQVEPASAMYRDVARQVKNKMGYDFKSPALLRSAFKHPSCPHNVCSLPNYQRLEFLGDALLDMVCVDFLYHKFPSADPEWLTRHKSTMVSNRFLACLCVKLELHKHILTAQASLLSQTQEFVAALRFAEESAREEALMEQEDAPKYLSDMMEAYIGAVFVDSGYNYDQVRAFFEAHVRPFFTDMSLYSDYALNHPVTNVSHMLRSDFGCDGWRLMTNEVVPPIEAGAGVITETQVLCGIMIHGQVYFHATAASGRYAKVAVAKMAITKFTDMDREAFRKEFGCDCQDVEGECGTQLADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ04</accession>
    <name>A0AAD9CZ04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_64943</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369108.1">
        <property type="nucleotide sequence ID" value="XM_060510276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ04"/>
    <dbReference type="GeneID" id="85394175"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="476" mass="51773" checksum="50D951327D0B7202" modified="2024-05-29" version="1">MSGPREKELHRARLVASVAATVISLACGTNYVYSAWSPQFAERLKLSSTETNLIGLSANLGMYSLGVPVGMLVDHKGPRSAVIIGSVLLALGYFPFHIAYDRAAGPVPLLCFFSYLSGLGGCLAFAASVKTSALNWPHHRGTATAFPLAAFGLSAFFFSTFGSLFFPGNTSAFLALLSIGTCGLTFFGFFFLRVYPHATYHSLPASDGLSGSQQLRRTSSEEAKPNRPGYGHRGAPVEPDIRGWALLREIDFWQFFLIMGILTGIGLMTINNIGNDVKALWRHYDESVDEAYLITKQQMHVSILSIGSFAGRLLSGVGSDFIVKVLHGSRVWCLVASSAVFFVAQLMALHVTNPHMLGLVSGLSGIAYGFLFGVFPSIVAETFGIHGLSQNWGLMTLSPVVSGNVFNIFYGRIYDRHSVVGPDGERVCHDGLDCYRAAYLMTLGACSIGLVLTLWVIRHQRVKWAKEEKMKAEQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D248</accession>
    <name>A0AAD9D248_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_602762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370490.1">
        <property type="nucleotide sequence ID" value="XM_060507191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D248"/>
    <dbReference type="GeneID" id="85391090"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="15954" checksum="3704A267F8D780FC" modified="2024-05-29" version="1">MNPRARTERARSPLRGHPGVSRLFWSGTLGIFRAGARWTGRTWSTVGRGGLLQRLHAVCMNSPFRACEIAWRKCSSLDLIGSASVAFPFPFGLLLFFSSSSFPEIWWMSLWVWCLCCGIGEASVGIPRAPCNSIRDEFSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Y1</accession>
    <name>A0AAD9D2Y1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_596872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371882.1">
        <property type="nucleotide sequence ID" value="XM_060506872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2Y1"/>
    <dbReference type="GeneID" id="85390771"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="68" mass="7151" checksum="CB6C94038C275127" modified="2024-05-29" version="1">MVEVVIGTLKSVRLAMASLCRGPGEGEGNSDSDKGRGVRKGADRQQERRNAGAVDAKAGPRTQLSNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2Z3</accession>
    <name>A0AAD9D2Z3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_290799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371016.1">
        <property type="nucleotide sequence ID" value="XM_060502188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2Z3"/>
    <dbReference type="GeneID" id="85386087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="217" mass="24456" checksum="EFD5CE11F6EC6373" modified="2024-05-29" version="1">MIPYFVVSWQRLSGSSHRRLERWPSHTWMGTKSVWGGSKVIQCRWWLEWLSATSDPKPTSRPFDTASPSRLNSKRCCRCQASRAVGHAWPWQSIIAVRVTAVFVVRVTFILQQSGRSMSVQTCSRGAVEALENDQSCSSTSSHTLFLRKLSEPPRGRGSRNRIVGSDMLMHVATDISMPVVDSRHRLIGPLVEPAHELLTRSWARVACRSLSRSPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3C1</accession>
    <name>A0AAD9D3C1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bifunctional lycopene cyclase/phytoene synthase</fullName>
            <ecNumber evidence="8">2.5.1.32</ecNumber>
            <ecNumber evidence="7">5.5.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_564698</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 (2E,6E,10E)-geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:34475"/>
            <dbReference type="ChEBI" id="CHEBI:27787"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>all-trans-lycopene = gamma-carotene</text>
            <dbReference type="Rhea" id="RHEA:32219"/>
            <dbReference type="ChEBI" id="CHEBI:15948"/>
            <dbReference type="ChEBI" id="CHEBI:27740"/>
            <dbReference type="EC" id="5.5.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>gamma-carotene = all-trans-beta-carotene</text>
            <dbReference type="Rhea" id="RHEA:32239"/>
            <dbReference type="ChEBI" id="CHEBI:17579"/>
            <dbReference type="ChEBI" id="CHEBI:27740"/>
            <dbReference type="EC" id="5.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carotenoid biosynthesis; beta-carotene biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carotenoid biosynthesis; phytoene biosynthesis; all-trans-phytoene from geranylgeranyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the lycopene beta-cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.32" evidence="8"/>
    <dbReference type="EC" id="5.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371570.1">
        <property type="nucleotide sequence ID" value="XM_060503672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3C1"/>
    <dbReference type="GeneID" id="85387571"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045436">
        <property type="term" value="F:lycopene beta cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017825">
        <property type="entry name" value="Lycopene_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03462">
        <property type="entry name" value="CarR_dom_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31480">
        <property type="entry name" value="BIFUNCTIONAL LYCOPENE CYCLASE/PHYTOENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00018909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1731515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="549" mass="60772" checksum="D4BE15560AAF85D4" modified="2024-05-29" version="1" fragment="single">FIVTIAFAATIPWDSYLIRTGIWTYPPNAVLGPTLYDIPIEELFFFVIQTYITAQLYIILNKPVLHAQYLNSPATLPKWIKTAKPLGQLALFSSVVLGAWLIAKEGGGTYLGLILVWACSFALLTWTITAQFILALPLACTALPILLPTIYLWVVDEMALGRGTWAIESGTKLELKLFGSLEIEEATFFLVTNMLIVFGVAAFDKAVAVCDAFPDKFDKPADALSMSLLRARVFPSSQYNMERILGIRQAVTRLARKSRSFHLASSVFPGRLRIDLTLLYSYCRLADDLVDDAETPDEAASWISKLDRHLSMLYKDPDATSAPLAAKYAAENFPESALSALDLLPSSLIPREPLAELLKGFEMDLSFSKDAFPITDPEDLELYAARVASTVGQACLELVFRHCQHNLPDYMQAYLRNTARQMGLALQFVNIARDIAVDAKIGRVYLPTSWLKEEGLTPKDVLVNPNSEGAGNVRRRILAKAFDHYGEARDSMKWIPSEARGPMVVAVESYMEIGRVLMRNGGAAADGSGRATVPKSRRIWVAWSTLMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7H0</accession>
    <name>A0AAD8U7H0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Permease for cytosine/purines, uracil, thiamine, allantoin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_594907</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000263">
        <property type="protein sequence ID" value="KAK1704422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357434.1">
        <property type="nucleotide sequence ID" value="XM_060506747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7H0"/>
    <dbReference type="GeneID" id="85390646"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF7">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1704422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="55556" checksum="7DD1BC694526F616" modified="2024-05-29" version="1">MERFEEKGRGEKTSPQACLEAGSGDLPRENGILAALRRFEGRMDKALGIEAHAIDRKTDADKKPVKWHEELTMALLWASGTMGISCFATGFLGWEFGLDLQRAIPIYIFGSILGGAVSGYCATFGAATGLRQISVSRFSFGWWPNKLIAFLNGLEQLGWASVGSISGGLALTAVADGRISLVVGVIIIAIVSLLVSFLGLRCILIYERYAWLTYFIIFMIIFDMVGPYADDVTPAQVTGADLSASALSLLAVVYGSSASWATMVSDYYVQYPTNVSRFKVFALTTLGIAIPTSIGMTAGAVAASSLNNQTAWKDAYENQGLGFLIRDMLHPRGFAKFLLVIFSFSGINTNIISLYSAAISFQQMARPFARIPRFLWTFLCFAIVIGLALGGRSQLNTYLQNFLSLLGYWCTSYFVILLMEHSIFRRGDFANYDLDGWNDPSRLPLGIGASVAFLIGVVAWCMGMVETWFVGPLGGLIGESGGDIANEMTLVVTAVAYLPARYLELKLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9I1</accession>
    <name>A0AAD8U9I1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_686111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000263">
        <property type="protein sequence ID" value="KAK1704427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357439.1">
        <property type="nucleotide sequence ID" value="XM_060511258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9I1"/>
    <dbReference type="GeneID" id="85395157"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="34"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1704427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="343" mass="37549" checksum="0C75ED515AC61824" modified="2024-05-29" version="1">METAHDETPLLNRQPAALGIIIVFLILAYLCGLARLYIRFCVVHRPGWDDGFLIIVLMTTTLLSIATCIALSNGLGKHFAGLGLIGMEAFIKIFYICNAAYCMATTFIKLALLSQYLTMFEFGSLSFRLTMIVAVVTAMWGLAYSTIAWFPCDPVSSQWELTQPATARWGFGSSDLGIYRRTYVSHVATNMVLDVLVCGLPLHWAWQHAAQKRSIYGVVFLFVLGDIVVAIGVSRLVSIVNTAAGTYPTLDPSWYGCVPAVLATVEVNLATVCASIPIVWPVTQRALSKIWVTREFEVISEPRDFRLKSTASSYDGDFSDRMPISSISGGPTRSTTVQATSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA51</accession>
    <name>A0AAD8UA51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Alpha glucoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_588106</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360271.1">
        <property type="nucleotide sequence ID" value="XM_060506102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA51"/>
    <dbReference type="GeneID" id="85390001"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000023">
        <property type="term" value="P:maltose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000149">
        <property type="entry name" value="MFS transporter, SP family, general alpha glucoside:H+ symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF5">
        <property type="entry name" value="ALPHA-GLUCOSIDES PERMEASE MPH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0462">Maltose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="488"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="65"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1715472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="62898" checksum="BCBA8175E3E55E4A" modified="2024-05-29" version="1">MVHIGSSAGRAPTETIQIDSEATRRMSIADADAAGLAREAAKATEAELSMGLMASIKLYPRAVMWSLFFSTAVIMEGFDKTLIGNLYAYDVFQRKFGEIQPDGSYQLTAAWQAGLSNGALVGEITGLFLNGIIAERFGYRKTMIGGLVGVTAFIFIIFFSETLVQLLIGEMLIGIPWGIFQTLTVTYASEVCPTHLRAYLTTYVNLCWVIGQLIASGVLRGVITRTDEWGYKIPFALQWMWPVPLIIGIFFAPESPWWLIRKERLDDARKSLIRLTSRNQQQNFNADETISMMVHTNELEKAAQSGTSYIDCFKGTDLRRTEIVCVTWAIQTLCGSTFMGYSTYFYQQAGMAKENAFTMSLAQYALGALGTVFSWFLMQHFGRRTLYLSGQGIMCAILAAIGFASLAGKSNVAAQWAIGSLLLVYTFMYDCTVGPVCYSLVSELSSTRLRTKTVVLARNLYNITGITTNILTPLMLNPSAWNWGAKSGFFWAVSCAVCFVWTWFRLPEPRGRTYGELEILFDQRIPARKFRKTEIAGLTHGAQFTDRISEKESMAAVSQIEKTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA86</accession>
    <name>A0AAD8UA86_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_757157</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359252.1">
        <property type="nucleotide sequence ID" value="XM_060514857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA86"/>
    <dbReference type="GeneID" id="85398755"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF89">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042039222" description="alpha-1,2-Mannosidase" evidence="10">
        <location>
            <begin position="28"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1711928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="570" mass="64902" checksum="9D9CA55E499BD4CB" modified="2024-05-29" version="1">MANRRQRRAIIIAVILFGLFAFHSLRSRSEPPPVVREHVNIRLVKSSFDWANHRHKYPVSPSRMHHLPTQRPKTLPRVQFNFGAKQLRKNDAKSESRRRAVREVFVKSWNSYKEYAWGFDELTPVTAKGKDTFGGYAATLVDALDSLWIMDLRDDFDAALSVIGAMDWDDTKETAVNVFETTIRHLGGLLSAYDLSGEPVLLLKAIELGDMLYAAFDTPNRMPPFWLDFQLAKEGKLVAGTSDPSASPCSLSLEFTRLSQVTGDHKYFDAIERVKLFLESTQRETQLPGMWPALINFRDESVLQHNEFTLGALADSLYEYLPKMHALLGGTDPAYEKMYRHAMHVVEQYLLFRPMLPDNEDILFSGTAFAEGDVRRNPESQHLSCFVGGMFGLGGKLFGIKEHMGLAERLARGCGWAYNSFPTGLMPEIFGMVPCETLDGCKWDEGRWKREGASGLKKGFSHARDPRYILRPEAIESIFLMYRMTGNPEYQEIAWTMFQSIVNATETEIANSAIEDVTVRGETKKLDSMESFWMAETLKYFYLIFSPPSLVNLDEYVLNTEAHPLKRQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAA9</accession>
    <name>A0AAD8UAA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_768937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000203">
        <property type="protein sequence ID" value="KAK1707938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358154.1">
        <property type="nucleotide sequence ID" value="XM_060515320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAA9"/>
    <dbReference type="GeneID" id="85399218"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042066376" evidence="1">
        <location>
            <begin position="22"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="130" mass="14580" checksum="A12EC644DAA1A3CE" modified="2024-05-29" version="1">MFCYFMAAMGGLSCLGILSGGAKDALPQWLSVVLPSEGLGYGTATRLMRPRSGVRDRELTCASESEARQKEWNQSSRTFGWMMKPGSWTLLDLGDKPLFYRLLRESRIGLYEVAYDIVRPEISFSSRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBJ1</accession>
    <name>A0AAD8UBJ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kelch domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_550857</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000184">
        <property type="protein sequence ID" value="KAK1709399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358533.1">
        <property type="nucleotide sequence ID" value="XM_060503488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBJ1"/>
    <dbReference type="GeneID" id="85387387"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF68">
        <property type="entry name" value="GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042134543" evidence="2">
        <location>
            <begin position="21"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="67"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="384"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1709399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="480" mass="51521" checksum="557B1D7D7996CF1C" modified="2024-05-29" version="1" fragment="single">QSIGQWSALVKFPVVPVAVALLPKTGELLAWSSGWRNRWTFPGNGKTYTSIYNPYSKEVTEALVENTQHDMFCPGISMDADGHIIVSGGSTAAKTSIFDEDTNSWAATGDLKIPRGYQSSTLTSDNKVFTIGGSFRGGAQGKQGEIYDTVSKEWKKLDGCSVTPMLTQDTRGSFRADSHAWLHAWKDGYVFQAGPSKAMNWYSTRDSGSVKGAGNRGSDSDAMCGVNVMYDAVAGKILTVGGAPRYDGVASTANAHVLTIGEAGGAVEVEKLENAKYNRGFANGVVLPDGKVFIVGGQSRTVLFSDANPQLFPEMWDPATKKFTTLKSHTTPRNYHSVALLMPDATIFSGGGGLCNGCTANHFDGQFFSPPYLFETDGQTLAKRPVVSELSISECKAGDSFTITMEEAANYTFSMIRMGTSTHAVNTDQRRCPLEAQANDKQYTVTVPGDAGIALPGYWMLFAVNEAGVPSVAKTFRVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBL7</accession>
    <name>A0AAD8UBL7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7029 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360032.1">
        <property type="nucleotide sequence ID" value="XM_060514761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBL7"/>
    <dbReference type="GeneID" id="85398659"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054293">
        <property type="entry name" value="DUF7029"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22974">
        <property type="entry name" value="DUF7029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042096251" description="DUF7029 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7029" evidence="2">
        <location>
            <begin position="149"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="561" mass="59128" checksum="14B0ABECAEE28ED8" modified="2024-05-29" version="1">MVRSSVIGRFLAGLLLASGAAAHTEGCSCSSDGIQRVTYIVVEMPDQPEQAASSLSSFTTLTTVPTPTSTERFTAQAAHVIEDIPAYEPIAIKPEALRPAVNTTHTFGATPAPGIDTKDPINIVPATNVSLYYAATDTEEQGSIDMKLAFKNPAVVLEHVNAVSNVACGDDELTVSFSSADTFAEAVKDWSDSAEEGFILITNHMGNCDAEFERGFFLATGLTSSEGDLSITVAASKEELTNIAGECEMSFTSLPAATLSKRLTLDPSVSLSFAEGLAENTVLYSDGQYVNITADEAWFSSKITFSGYLKYNFWGFKLQALYFDLDTTFDSAVGVSVDVAASYSHALKYAPDALSYSLVSVPGIVELGPGVAFAVGLDFDVSAAVGVTAGLSVSLPGGNVHLDLLHGEKSSASGWEPKYSSYANITESADVRVDASADVTVQLAFKLLGGLVDLSSGITATPGFDNVFKLRGEQNLGVSGTIGSGSSSSSSTIGGGNFTSKPAELTQVSVDVPKDGLICAEKNGVEFATDFYFNLTGFATKWWSGELYSTRVPLWDLCYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBN5</accession>
    <name>A0AAD8UBN5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_62496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360062.1">
        <property type="nucleotide sequence ID" value="XM_060508475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBN5"/>
    <dbReference type="GeneID" id="85392374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="94" mass="10583" checksum="B5CDF85C02EBB395" modified="2024-05-29" version="1">MPSQIVKRLSQSTTEHAVRFFLPTFWLRHASASPSTLSNPGPNVVFFLHAPHVNRNSRDFHVLHIKGPSLPFPSTLVCRCLHRVVLAAHRPSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC61</accession>
    <name>A0AAD8UC61_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_635562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360332.1">
        <property type="nucleotide sequence ID" value="XM_060509188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC61"/>
    <dbReference type="GeneID" id="85393087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1715533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="20997" checksum="6B9995841127B28B" modified="2024-05-29" version="1">MAASNYVTRQYASEAFVESCGAIPFDLSKDPARVCLLHYLSTDEWLLAKGRRNYGESRHEAALREVHEETGFRCRLLPVDMATRAPAPDDDANAPDQAAARRGLTEPFMLTMRDVDGGSGVKLIWWYVATLEEGTAVEAAGGEAQFSASFFSLDEAVQRLTFEDDRNVLRKATQIVKQTALGPYAARFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCY6</accession>
    <name>A0AAD8UCY6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360568.1">
        <property type="nucleotide sequence ID" value="XM_060512508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCY6"/>
    <dbReference type="GeneID" id="85396406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="123"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="386" mass="43080" checksum="2BF0B1A87ED0DDDB" modified="2024-05-29" version="1">MSISRPQLSLWEKRDLVFRLLFRAPIQLAWNFFYGIPFAIARGVSIRFFAFCAYYRFALGSMRAREIQFLIPPSIKTYEKWIAKKQKRHPELGDKLQKKIETLPANDGSILWIGNRQKATKFVLFFHGGGYVVPLLPGHLDWCWNAYVTGGPGAHAEVAVAVLQYTLVPEARYPTQLRQAIAALNQLILSGIKPNDLLIGGDSAGGNLACSVVRHICHPCHLEIPALRLENRLAGVFLVSPWLSSKTTTPAFTENNYVDMLTTTCMSRATAELLHPRFPVRNKSDESDLAMAMPMDGDMAWVDEISAATKSLYVTGGQQEAFRDDIRAFSEHVSCGNNDLDLLVELPEREAHDFILLEGQTGRVGDATVRMRNWASSQLGTGRASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDG6</accession>
    <name>A0AAD8UDG6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clr5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_93330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359553.1">
        <property type="nucleotide sequence ID" value="XM_060516015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDG6"/>
    <dbReference type="GeneID" id="85399913"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025676">
        <property type="entry name" value="Clr5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14420">
        <property type="entry name" value="Clr5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clr5" evidence="1">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="556" mass="62121" checksum="DE902B409C6D2FFC" modified="2024-05-29" version="1">MASEHMPAFEILGNTFWASPAQSYTINELGMGMAKGEKETRPRAARIPAETWEKMRSNICEEYKTKTLEELIKFIKDAYGLNVTKRQLVYRLGLWGCGKYNLKDYKGEQGNEDSDHNDEEFGPDGGHVNEATNALWPTSCFEAGSYAYDQVNQNIRAATAIFAAGGGSDGFAWTAYKDGSLNTVGHANRLVALCRSAETEEQFQESLGALEPHKLRSGDQHILMYVHVLESMNDERYRNDRYQLEGPMARNLAYAVSAILDSSGKGFLLKEDGTVDLFAFQLLDVIYERYSAHLDKSQEGKLRILLDCLEGWVLSRDKNGATTSAALDTLRKCVQWCYQMLEKVCNDFAKTKRPVLCCADSQDDLIWKEHLEVYGTLWYRLASQQEDERAGNVEREEEGEEEGADGLGWARHAREYLGISHAEVLSYVCWVFVNHEASSIIMHGTGTVDMTTTAAAANGYYGGLGGNGYNESSPESLFLRVKAAANVMTGAEPRDLWHGFLYAFKDFNDLTGGNDAFGDVAARAAEYKRFRGWIVAEFAGFVRDALNELEISLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE76</accession>
    <name>A0AAD8UE76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_416168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362607.1">
        <property type="nucleotide sequence ID" value="XM_060502948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE76"/>
    <dbReference type="GeneID" id="85386847"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042271553" description="Secreted protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16063" checksum="08368D28E4C72E27" modified="2024-05-29" version="1">MIKRCGAWVRIYNLSALLSSLLTSSAKLCSNSVHYRDPEPTTRLPELASSTHVSEIARPCEVRGTRRLEKEKALRPEAERAGGVTSTPDWRVDLGPSASTGIVSCTVPMPSASISKSACLRLNIVSRQCQSRQGIAPSTGQKQLTMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE84</accession>
    <name>A0AAD8UE84_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_589155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359779.1">
        <property type="nucleotide sequence ID" value="XM_060506206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE84"/>
    <dbReference type="GeneID" id="85390105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="671" mass="76072" checksum="6108EE4483345B16" modified="2024-05-29" version="1">MSTKSTDKPFQCPACSSRFTRQQENLNRHTASVHQRSNLRPFPCPQCEVSFSRSDLRKRHVRRYHANPDRTGETIHVASHAAPADEPTKETNKATEANRSIDLSNGQGISWLFKLPQFVSAYFDRFQPTFPLLHKPTFDLDTAQEPLIQAIVCLGAIYQVQGSGQEISATLFSSGLKSLDVYVSEYTRSRRVRFRELWVMQAYLLFEYYAFYSCDDGRFSTALKIHRKLVDAVRQYQMLQDRVALGVDEVSSPNEPAVASSMTETEHAWRVAMYNESRKRIVYCLYYLDAQLSVCCNIRPLLAALELKYELPCQDDIWQAATAETWQALIFSEEGSFNEEDDYEANGDPRPAHGDLYASLMYLMNPNPPDRPLRLLWHSSFACLMLMTQILMMIRDLTLASSFLYNNVRCGESKNNLSIISEASRTSIMQALNALSDIMRKPSLPGTCPLSSPLYDSKSVESGLWSNVWIVWHYAAMNLTHQEALLTSGIVEYSLPSAVSTCWELGKPRVKQHRDVYEDRDVMRVASSLESILVLLSHDTRPIGINFQLQSEFTPKTIEDPFITMIGYKACLLGWRIVRLMAVSLQASSASFNIQAQSIYSMSARVVLTGILAAISSESANQRGQWDSTAAVDDAESRYLTWMEATFLARDVWPPGKWIVAVCNESRHETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE88</accession>
    <name>A0AAD8UE88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_655910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360195.1">
        <property type="nucleotide sequence ID" value="XM_060510829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE88"/>
    <dbReference type="GeneID" id="85394728"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="157" mass="17543" checksum="0CF770BE215F095B" modified="2024-05-29" version="1">MSLAGLRYLRQNPGFPTSHSEPRIAGSSTESNEPLGITASTSFTIATPEPHNRPSEAVMAFNSSTKEEKFSIRHFGWRQRDGPELFATGPSSFPDSTYHGGNYYFLLRIGGFQPSDNFRRVALFHSNENGDNVLETSLLGHRMLPSAWNLRRISRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEG3</accession>
    <name>A0AAD8UEG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2-16 kDa</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">E2 ubiquitin-conjugating enzyme 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_56582</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360300.1">
        <property type="nucleotide sequence ID" value="XM_060503802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEG3"/>
    <dbReference type="SMR" id="A0AAD8UEG3"/>
    <dbReference type="GeneID" id="85387701"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1715501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="147" mass="16480" checksum="2C1877D34F37D955" modified="2024-05-29" version="1">MALKRINKELTDLGRDPPSSCSAGPVGEDLFHWQATIMGPGDSPYSGGVFFLAIHFPTDYPFKPPKVNFTTRIYHPNINSNGSICLDILRDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKTDRARYEATAREWTRKYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEL4</accession>
    <name>A0AAD8UEL4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Concanavalin A-like lectin/glucanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_675306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362832.1">
        <property type="nucleotide sequence ID" value="XM_060511150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEL4"/>
    <dbReference type="GeneID" id="85395049"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289854" description="Concanavalin A-like lectin/glucanase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="26626" checksum="DF6A11DED67D4F97" modified="2024-05-29" version="1">MRSFSSIAVLPLAARIVAAGQYDAWKFGNMFTLGSDSSVITKATYTLVPPSIPCGTVISNKNDQPWMSIWVGISQSVSDQGSDLFQPLLNWAPDNSAAGCPASNTEWCVAASTFTGSTQVAQPYIAIPSKSDVDFELVYDASKGVTQKVWINGAMVSQQTDVDGNGKAPTYIYSSNECYQGACGTLPAYSWSNLTVVLAKADKTFGDSLQLTGATSTGVKTTDDGKTWHVDAIKINQDFFYTDGSNKQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEL7</accession>
    <name>A0AAD8UEL7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_60883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360126.1">
        <property type="nucleotide sequence ID" value="XM_060507497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEL7"/>
    <dbReference type="GeneID" id="85391396"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="133" mass="14338" checksum="06AE3CAFC8F7B6C7" modified="2024-05-29" version="1">MVSLEPYATSNPSTDIPPSQMRLPSILSTTLLAAGRAQAQNCVENGPTDDAITGFRFSGTCESWQWFSRDKGTQVKLQPDCFLRQTFPNATPVGHVCIQLESGGHKCFSAPGAGAPQCRVPDDFCSGIQNMWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF27</accession>
    <name>A0AAD8UF27_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_587532</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000116">
        <property type="protein sequence ID" value="KAK1716145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360539.1">
        <property type="nucleotide sequence ID" value="XM_060506059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF27"/>
    <dbReference type="GeneID" id="85389958"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF15">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8 16" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042180360" description="tripeptidyl-peptidase II" evidence="16">
        <location>
            <begin position="18"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S53" evidence="17">
        <location>
            <begin position="203"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1716145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="585" mass="63366" checksum="BF4830C8D41E782D" modified="2024-05-29" version="1">MRLSSVSALLLSSFALSQPTTSGHAVHEAVKQLPQGWRHVATADDLNTIQLSVALKQPGLSELKARLEVTSDPNHAEYGAHVSRDLLEMFQEPNTDAHAVVATWLFAHDIRNFVQDGAWVRINTTVGKANRLLGCKFSKYQYKSEKAVLRAKEYTLPSQVSEVVDFVFPVTQFMSKPPRRQIKSRESGKVKRQSTMPRSCWDYTTPDCVVDLYNINYSPPNGPSPTDFGIAGFLEEYPNVPTLQAFLASYSPRRNATAFSPKYNLTVESINGGSDTTEGGGVEALLDIQYSMPFIQPMNVTYFSTGGRGPEIGPDGKEKDPKDSAHEPWIEFLEALLARETIPDVISISYTDDEQLIPQPYARRVCDLFMQVAARGVSVLVATGDGGAAGIGSGDCISNDGKNTTKFIPTFPVDCPWVTGVGATGNYAPTEPAWYSSGGFSEYFERPAWQESAAKAYIAGINGSHAGWYAPNGRGSPDISAIGSRFLMQPGWTQKGTSASTPVVAAMIALANDKRMREGKPALGFLNPLLYSDKVRSAINDVTSGSSGSCSYGTKVESGWSATAGWDPATGLGTLDFAKFLQALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFX9</accession>
    <name>A0AAD8UFX9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_588719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359990.1">
        <property type="nucleotide sequence ID" value="XM_060506165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFX9"/>
    <dbReference type="GeneID" id="85390064"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF274">
        <property type="entry name" value="ALPHA-CARBONIC ANHYDRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042084387" evidence="1">
        <location>
            <begin position="19"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1714528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="30567" checksum="6FDA933747C106EB" modified="2024-05-29" version="1">MITTVFLGALLMASDVLACAGHQNHYAMADRKRAEMAPLPAADWAYEASFNWGRLNPNYTLCQTGTQQSPIALSLNNGLALNHILRFNYPNQTAGNFYNWGYGPAFTVTHPEGVYTGNPSFTYDDMKLYLKGWHIHSPADHSVNGDRSKAELHLVHVDEEGHEKAVLAIRLDPGNANNTFFDQLPPMIGFNDVGVQQEIEVDHMPALNSVLQFNEFWTYRGSLTSPPCHEGIRWFVARQVMFLGVDQMRAILGASTYSARAEQEVWQHRINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG80</accession>
    <name>A0AAD8UG80_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_633107</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000103">
        <property type="protein sequence ID" value="KAK1718124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361124.1">
        <property type="nucleotide sequence ID" value="XM_060509010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG80"/>
    <dbReference type="GeneID" id="85392909"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="112"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="35914" checksum="3B497F442E1DCF5A" modified="2024-05-29" version="1">MSSHTAKAARSASQALSRSSSLIPRQPHFPTPAIASRSTTTTTLKSFANCCSSTTSTPLTQQLHKSFSTQAAKMSTMPAQHGHSEGCCNIPPVVSKGYDAKGSYEEIGSKKTYVTGPADAKKAIVVTFDIFGFFPQTLQGADILATSGAEKYRVFIPDWFAGEPCPIEWFPPDTEEKQKNLGGFFQKFPPPKIAEQTPDYVKAIQSKYSSIESFATIGYCWGGKVVSLVTSGDKNPFKVAAEVHPAMVEPEDAKGIKIPLIMLASKDEPEEDVKKFEANLNVTKHVETFKDQIHGWMAARSDLEDSRVKEEYTRGYKTVLEFFGKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGI3</accession>
    <name>A0AAD8UGI3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_633685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360919.1">
        <property type="nucleotide sequence ID" value="XM_060509050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGI3"/>
    <dbReference type="GeneID" id="85392949"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1717432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="660" mass="74646" checksum="1B06A5078782A7BB" modified="2024-05-29" version="1">MENPVMVVADSQQQGSHEVAARALSDRPLKRDPACVECRQRKLKCDRKYPCSECIIHGRHCLAPPPSGPRKPRRKNHHELRDKLASIESLLEECMGSKPIDLANETPPVLIDKESPTDSRNHDDHRPMLQSPGWLVNTKNGIEFRDSKTASATREDKQTIRALFEVESEQSTWLPALAILNQHHDSIGIPPASGLSSNCVPSSPNIIILWRVFLDRVNPVTKIIHVPTFQANIADAVSHFHAIPPVTQGLLFSIFLAASGSLSQKEHWEMLHWSKKDASRVLSKGFKTAMARYNYLRRFNEDTVRSLIFYSLHQRTLRDLVDPWILNGIVVNIAHHLGLHIDGTRLRFKPFQTEMRRRLWWQTVLIEAKTSAASSISARILPSSQDTCIPLNVNDEDLHPYMKEAPSARKGPSEMSYCVHTYEAESLAMDMQIPSVDEVLWGQASSSPASTHAAMRPPEPFDSPFVTAIQDALQRFDRTLGPLERRLLSNSAANPLHAMALYARTSLAAIVEKVITPLDAAPEWGTEMHGPDDKFFSVGLMVLEILLEQRRLAGHKFAWLVDLDFKIQTFYYLGAQLQNRVSGSLADRTWAVIEKMYACREDLWELKDEENMTLANLLIVAWSRRAENFLGNRVLLLEPPLVTRLRDEVMMIKAEALSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGL2</accession>
    <name>A0AAD8UGL2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_388956</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363571.1">
        <property type="nucleotide sequence ID" value="XM_060502772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGL2"/>
    <dbReference type="GeneID" id="85386671"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="85" mass="9796" checksum="0FF0FA5AB6122A76" modified="2024-05-29" version="1">MPFSSLAIQHTHAHSHKFCSQPLTLVIAHEVTITKTKIGRFRWQILFFVLLGHHLLCPSYQKYRSLGILIKCSYIGSSRGMKRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHR8</accession>
    <name>A0AAD8UHR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">(S)-ureidoglycine aminohydrolase cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_454479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361833.1">
        <property type="nucleotide sequence ID" value="XM_060503173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHR8"/>
    <dbReference type="GeneID" id="85387072"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010424">
        <property type="entry name" value="EutQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36169:SF1">
        <property type="entry name" value="ACETATE KINASE EUTQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36169">
        <property type="entry name" value="ETHANOLAMINE UTILIZATION PROTEIN EUTQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="(S)-ureidoglycine aminohydrolase cupin" evidence="1">
        <location>
            <begin position="60"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="139" mass="15248" checksum="37C56E87490837F3" modified="2024-05-29" version="1">MSGNLVPLTVIKGAGHEYIPLPEGENATVADFHSIRTNTKDSPAHFTSGFYKIVAGPARPAHYNFEETKYVLNGQIDILDEATGITHHLVPGDFAFFHVGSKVKFSTNSEGLAFYAVTRPVRVPHPNLKGREEDTKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHS7</accession>
    <name>A0AAD8UHS7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase family 31 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361761.1">
        <property type="nucleotide sequence ID" value="XM_060505778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHS7"/>
    <dbReference type="GeneID" id="85389677"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000036">
        <property type="entry name" value="Putative glycosyltransferase family 31 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006740">
        <property type="entry name" value="DUF604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10811">
        <property type="entry name" value="FRINGE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04646">
        <property type="entry name" value="DUF604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58982" checksum="5469669D56A32CA6" modified="2024-05-29" version="1">MALTLRNDAIDVRGRIMKTGAGVKSSITHQQPLDPVKSHGSSSLSEKIPAEPAPSSSHVMNCDINTDHIKTLKDKYGLSEKIHYFKRYVRFSRKPIQRKGYTVLDQEFLPKKFKTVDITKSYAPEECHEPLDVPVTQSSYPSTVNASDFMFAVSTTYKRFNDPKTSPIKEWAHWLTDSNGKSNGGKLLLLLLDASDAELKDASDRLKRVGIDADVAHSDPSMEMAVRYLTLVPYLYNHPERKTRKWLVTCDDDTFFPSMHGLIDKFATFDHLDPLYIGTLSEDVNAIHRHGSQAFGGAGVFLSVPLAAAINQLYESCKTETKIKEANSGWGPQGDILLRKCIYENTEVRLTNIWELWQLDLYGDPAGFYESGIKPLSLHHYKGGGWHYAKPLQSAKVGHACGEDCAYQRFITADDFIIANGFSVAHYPQGIDFNLDQMERTFTPAPDDIGWNLDYMFGPQRRSLHKTGRKIAWELQEAHVQEDGSVLQVYTRRKDDERWVEEDGEPMSKIDGVIELVWIPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW1</accession>
    <name>A0AAD8UHW1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AN1-like zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_655201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361040.1">
        <property type="nucleotide sequence ID" value="XM_060510785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW1"/>
    <dbReference type="GeneID" id="85394684"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057358">
        <property type="entry name" value="UBL_ZFAND1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25327">
        <property type="entry name" value="UBL_ZFAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="5">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="5">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1718040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="311" mass="34455" checksum="C7F454D8424B8087" modified="2024-05-29" version="1">MASSSTPEETSYVKMDESKDGFDETLVGKHCEYEYCNQLDFLPFFCQSCKHTFCLDHRSETTHKCANAGAWAERRRKAELAKPSYGQGRQLRDTVTQKPCASPTCKTTIGTSLVTGVHCPGCNRDYCLKHRLKEDHDCKNLVPLGARPGSQIDVAARTKSAFDKLKAWGSAKKEQAGRALPKPKPTSASARLIAVNNLKKTAKGDDKLAQEKRVYLYVEAEAATAKAKFPKGEFFFSKDWVVGRVLDEAAKRLQVENLNNRSSNEQDKLRVFHVEGGRLLEFNEKVGASLVSGNTVVLLRGVGPPPDLMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHW8</accession>
    <name>A0AAD8UHW8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT-NTPase and P-loop NTPases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_584145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362010.1">
        <property type="nucleotide sequence ID" value="XM_060505732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHW8"/>
    <dbReference type="GeneID" id="85389631"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031352">
        <property type="entry name" value="SesA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17107">
        <property type="entry name" value="SesA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT-NTPase and P-loop NTPases N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="225" mass="24532" checksum="36598C2AE108E136" modified="2024-05-29" version="1">MDPLSITASTLTVIQSLLATFDAIKHIKGLPAAFKEVGKSLPLVENTLQLAHEALKAEKPDAAAEKELIPALGDCQKRASTLRDIFKDIEGGKNQEKEAKEWSALVKFYHNKVVPLGKAHKVESLMQDILKKLKVLAIRQIFKASAELQKQVGGLEDAIRSLSEVDPSLPDSDFDAASSNISMNNYGKAKGFVSTGSNADIAMGDKYQSGHNMYFGRRSRDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIY3</accession>
    <name>A0AAD8UIY3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_651920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364801.1">
        <property type="nucleotide sequence ID" value="XM_060510492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIY3"/>
    <dbReference type="GeneID" id="85394391"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="342" mass="39567" checksum="4FD0E7BBA601E5A3" modified="2024-05-29" version="1">MAPKVKAVKSKAPKKAAVGAPPKPFKKPAEVLQPFIETLDPKHVYITHIDSKPVEFKKKIFLVPVGMNLAVAALFVLRMYWILPYYFKFVQSALGYPNETTFPTADSTWGQLLWEVAKRGGSLTLDLMLFIFVWPWPVEFVFGTSYSNPVSWRRKIGFREKEIYVRRSREWDQQLGDIFKDRERNEALQQVIRQACSPLLLQEKTGYLTMTGQWDLDWQAMIDAHTMVDRNDVALDAFRRLVLVYHEDFGWMSVEEEGVTAKEDDRRRQVFQFRDALNAIGKENLFFRWIEIVQFESSQPGGFGPEKQTVVAKQIRDLFQKEGVDFDQVWHDAVGSDGLSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ21</accession>
    <name>A0AAD8UJ21_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Inactive metallocarboxypeptidase ECM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Inactive metallocarboxypeptidase ecm14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_580143</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363752.1">
        <property type="nucleotide sequence ID" value="XM_060505316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ21"/>
    <dbReference type="GeneID" id="85389215"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000060">
        <property type="entry name" value="Putative metallocarboxypeptidase ecm14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF147">
        <property type="entry name" value="INACTIVE METALLOCARBOXYPEPTIDASE ECM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="17">
        <location>
            <begin position="95"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1723697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="49817" checksum="5B9005A125AAA714" modified="2024-05-29" version="1" fragment="single">ETAFAAAAARTFLDIWAFNHEFVDVRIRQDNVRSLLGLLPDSLKSAYSTLISDVAAAVYDTYPAVDVPAQTYRIPNGRANLKNAQNGNENYFFQDYQRLDTIVQWMRLTEAMFPAITEVITIGQSSEQRDILGLKVGMKTRAPGSEKRKTVVVAGGMHAREWISTTTTNYVAWSFITAFGREPMITKLLEHFDFVFIPAVNPDGIEYTWTTDRLWRKSRQETGMSWCHGFDLDHAFGYEWGDYSENDPCSESYGGKQPWQAAEARAVALWARNASLEDTEFIGLIDLHSYSQQVLFPFAYSCDVDPPNVENLEELAAGLAKAIRLSNGELYSVTSACEGAVAGRGSAPDAKRLETGGGSAIDWFYHELHAHYSYQIKLRDTGSYGFLLPRENIIPVGEEIFSAMKYFGDYLLGNNGIEKSVGASTPTPDEPDRSLELRRLRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ70</accession>
    <name>A0AAD8UJ70_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_544364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000096">
        <property type="protein sequence ID" value="KAK1719421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361505.1">
        <property type="nucleotide sequence ID" value="XM_060503435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ70"/>
    <dbReference type="GeneID" id="85387334"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1719421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24214" checksum="424F632106D48760" modified="2024-05-29" version="1" fragment="single">SAAITFLAAAYRLDILILNAGVMNVPAGSVTQEGYEMHFGTNHVGHALFVKLLIPILQTTASEGNVGSGKADVRVVFVSSVAHKYPPSGGLQFDSFHPKGQSEILSANALYGQSKLANLLYAREMAKRHPEWTTVSIHPGTVKTDLQKSTDGSLLIRAFQKVVVPLIGVDVEEGARSQLWAATAHGVENGEYYEPVGVAGNGSAFAKDNNIALKLWDWTQKEIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF4</accession>
    <name>A0AAD8UJF4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fibronectin type III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_579861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363947.1">
        <property type="nucleotide sequence ID" value="XM_060505286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF4"/>
    <dbReference type="GeneID" id="85389185"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF19">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="265"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="541" mass="60154" checksum="8E07D09AE0FC7350" modified="2024-05-29" version="1">MGDIIQESVRPIRIMVVGDSMSHGREGDFTWRYRLWQWLKEENINVEFVGPYEGTKTPDQPRPPQPPPLKDDSLPAPDVPIDHGGYAAGVQFNSHHFSVWGRQATQCKDLIKEQVARFRPDYLLVMLGFNDMGWGVADAENTLSAMKTLVDNARTAKPDVKFALADVPMRTPIDGAERLPGMIEEYNQLLRTSVSKWAAFESPVELVGVRRGYHCHQESYDGLHPNSLGEFQIARAFSQTLSQKFHIGIKALTIPQGIPQRPTPVPANIVAEAVSYGVSVKWDPVYGAIGYDVRIRNHDNLPWNESRADVAQYNSTWTQEGQEYQYQVRTFNGESLRSSWSTTASTIAHPKTAPGPGNIITKPDLYQVLVEWEKPQGQAEVDRYELILVDLSLPGSFPATVAVRENDTTFTDLSTGHRYGLAISTWTDCGGGIPAGGRSFIAGNGKPPTPTQLQIEVQNPTTVHLKWEESKGAAGYRIWVRNLVEKSDFVEDGETDSAEYGITFLIPGAWNFEFCVSAYNGSLESERSGSIAPIRGDIESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKF1</accession>
    <name>A0AAD8UKF1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_754618</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362195.1">
        <property type="nucleotide sequence ID" value="XM_060514499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKF1"/>
    <dbReference type="GeneID" id="85398397"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000208">
        <property type="entry name" value="3-ketosteroid dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF10">
        <property type="entry name" value="3-OXOSTEROID 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="6">
        <location>
            <begin position="49"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="596" mass="63903" checksum="E5B84B0F89456203" modified="2024-05-29" version="1">MMRSNVVRGTNLTRLRPTPSLSLHRCRSVLQPNRRFSEKTPSTADEQVDILIIGSGAGGLTAALRSRTLGLNPVVIEKEATLGGASVISGGGLWIPANPVSRAAGIADSKEDALAYFDQAVGDVGPASSLAKRKAYLDNGPQMISFLRDLGFEWRFSRGYPDYYPKMKGAMGKGGGRTIESVAFDTRKLGKWRDALPPANIPVAIHGEQAPWITMMTASLQAFIKSTRIMLPIIGKTISGQKLVSLGRGLIAQLLFLNIKHSTDIRLRTSLLDLTVSQSGKVTGAKVRLPDGSTRTIKASRAVILAAGGFAHNKPLREKYGPIPASTSWTNSPKSDTGDAVIAGQTLGAATALMDDAWWGPTIFDPVTGKPHFALIERSRPHCIIVDNAGKRFMNEAQSYTDAGHDQYERNKSVKAIPAWLIMDTNHRNRYMLGTQLFARMKPKKPVADGTMFAASTLRDLAKQIGVDAEGLEGTVTRYNDMCKTGIDEDFGKGDNAYDNFFGDPAAGGPNPNMGALSKAPFYAIAIWPGDLGTKGGLLTDEHQRVLKEAGEAIPGLYAIGNTAASIMGRTYLGAGSTLGPAMTHGFLAVNYIAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKU0</accession>
    <name>A0AAD8UKU0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_620554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365188.1">
        <property type="nucleotide sequence ID" value="XM_060508198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKU0"/>
    <dbReference type="GeneID" id="85392097"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05652">
        <property type="entry name" value="M20_ArgE_DapE-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF14">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="183"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="365" mass="39284" checksum="748BA3E5D144CA3C" modified="2024-05-29" version="1">MPKSISQTRNPSQLKAMASAIMEHPVVGLLKSLMSIVSTSELEESIGVFLEHHLHSLGFTVERIPISPDSSRHNVYAYLGSSRKTRVLLTAHMDTVPPHIPLTIDGDIIRGRGSSDDLGPLAAQILAAEELGKEGKVQEGDIALLFVVGEENGGNGMIAANDMGLKWESGIFAEPTESKLAKGHKGQVAFEVIANGVACHSGYPHLGKSATSALLAVLNDLSAATWPESDLLGPSTFNIGTIEGGEKHNIVAPSAKALCEVRMVSDLPGIKTKVAEIVSRHPDVELKFVFEYPEALLQWEIDGFDAAPVAFGTDVPRLKAEYCDNRVLYGPGSILVAHGPDEFIRVPELIESIEGYKKLVLHFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKV9</accession>
    <name>A0AAD8UKV9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nrm1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_752297</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364772.1">
        <property type="nucleotide sequence ID" value="XM_060514178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKV9"/>
    <dbReference type="GeneID" id="85398076"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468:SF1">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40468">
        <property type="entry name" value="YALI0A15257P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="211"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38908" checksum="5FA5265C0F344A9F" modified="2024-05-29" version="1">MSSVWKQQPEEVADKVLKRVEVSKIARRLQNRLALAQFKTKHGWEDLTLDTIEPKYEEELRRKRLAEGDLLSDSSSSASDLPYPTRALMSSPLKAPLFSDAIGSSNGSTGHRKRTYMASFDCPSSSPSKRYRSSPTPIKSLHGHTSWKESHQLAQSSPIKPRRQQHFTTSTGPDVSFFQGARRLADDLVSPNFAAASDDEDDLLPVQSFRTTNIRSSPPTTPPMRNRVLPNRRTRDQGANGEPVKSGQEGADLLLYLAASPSPAVPSTKTRMEPPSTPPSKVSRDMTLPSSHMTTPGGGNMFPNTPGQGFDFADFVNITPSPAQKAWKTPVALSSARTPVSLARRRLTFDEPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL81</accession>
    <name>A0AAD8UL81_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase/esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_627150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363199.1">
        <property type="nucleotide sequence ID" value="XM_060508613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL81"/>
    <dbReference type="GeneID" id="85392512"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="87"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="359" mass="38955" checksum="8BA28D758F608ED6" modified="2024-05-29" version="1">MGSLENKTSVDKMEYDTKEKLAALSVIDLEIAEYLAGEHPLPESAPPAPDTEFEYSIQIPMRDGGREQEARVHKPSTSTGAKSPVIVLIYGGAFTMGDCHQMSPWARIARKLFNATVVNLSYRLAPTHPFPAAPNDVEDGLKWVSENAHTLGGDLNAGFIIGGPSAGANLAAVMAQKTVDGITKLGAPLTGVWLLAPLFLEDDIVPPEYKDIFLAREQNAEAPIFSKAAWGYLAANYKADIKSVDYSPFNSKNPHVGMPPTVVQVGGLDFLRDDGLVYEKALRAHGVETRLDVYPGAPHGHFIFPGIKSAFKANIDIFKGLGWLLKQETSEDEIKKAVVADPFMTVPENSSTAYDAVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULG8</accession>
    <name>A0AAD8ULG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TTL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_626150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363576.1">
        <property type="nucleotide sequence ID" value="XM_060508544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULG8"/>
    <dbReference type="GeneID" id="85392443"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="479" mass="53900" checksum="DE6B5C2C0A1F07DB" modified="2024-05-29" version="1">MYAYVQPASPWLSEHIKSYIRKHAPETKFIDDFDHFPTDAKTVFQFCDGWALNRNFAALNSATTGLINTYPNSDALARKDYLARVVELWTAKRPESILKKHVPATVRLSLDYAEYVEESLTAADDLSLLYSLEANESKPPTERDWWIMKPALVDCGAGIRLFSTVDELANHLELAEYEVEEEDESILVYKSQQPIPDTTPYSEKGDTDFSPTLSTPGLDSLDVLVTATGALSLKPILEAIQRSPKPQYLFKEGGRIPSAQMREFVAQQYVVSIPPMEKRKWHARAYVLSVGRLKVYVFKEMLALLAGEDYEPPWLYPSLKSSLTNTALQDEDVFVNRDSMRDLWDAPDDLLPGDWKAHVFEQVCAVSAELFQAAAHTMADKFTTVDKCFELFAVDFLIDSSGTAWLLEVNETPAFYNVEIAGPLALRLMESVICVTMEHMGMAQPEGYNHTSAKEGLIQVLDETEKLAKSNITEILPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULN5</accession>
    <name>A0AAD8ULN5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Abc transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_574079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366627.1">
        <property type="nucleotide sequence ID" value="XM_060504679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULN5"/>
    <dbReference type="GeneID" id="85388578"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="49987" checksum="36CC7FEB9E5DE955" modified="2024-05-29" version="1">MSMPGAFSPDLSPFEPDSKKDDASSAAANPPPLRLNQPSDAFSLHTNDPYYDDIATASSSNAGDLPPSYTDEPSSLDPKHNITTTVTPLLADESGHSPLLFRRDPETGAEIHCSRRLDTDPAFLESHITSLAQSPPRPYLRVRGTHTESIRKRDDKTESKTVVDFDVRVELTPYLYRDIATRRSWRELRTADNFSKVRRGTVFPTRAPGFGGRSSGARGGAAGEEVSKEPPTLREWCHRYCASHAGLKTFSLLRTVPGFDDDERLKARLEDLVRATNYRGRIDVSFPVHDSTVEIYNTCRVNRWRQTTWIRWLFYLTFLWIFAWPYLFFRTKRFEVVEAEWAFSRRRRDPLTGAAGGRDYVSLSEADLYNMWARAISKAVLERRQGELDQRDLRDAEGRQDTSFEDVLAGIDQETTRGLVRAGVSAMNVVNRHFGWGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN84</accession>
    <name>A0AAD8UN84_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase II-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_750452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367006.1">
        <property type="nucleotide sequence ID" value="XM_060513919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN84"/>
    <dbReference type="GeneID" id="85397817"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="51425" checksum="6D24B4D1F5F709C4" modified="2024-05-29" version="1">MSSSAPRGGERMIHQDFIARIRYSNALPPPPNPPKLLDIPNTGLASGQYTTPGFASRLAREQPLNIEVDAELGMPLDLVGMPGIFDGDESSIQASSHPPAVHPHDRALLRPLSTLGRAKSNADASVSFLRRTEYISSVAPRKAGVAAGAFINPKIKRAEKRRSPEPDKDSPAAIRRKIEKSFESAERFLSNPTRHRHPSKPNVHLTQSLPLLPDHDAFPDSGAYVTVKLLTNPVASANKYDSRLLSGLLRPLDRSPEENEAFQAAVEAHERDPARNPKPANLMDYSFFLPKTKTTGDNFRAKFDPENPDRDDESLYTYQSGSNPCFQFSRLRAYETTKEIELDHNTKYSEEVILAFNDEPSAGGRPKAAYYYPVIQRTTIRPQRAKNIARTLSQVDDETQVVNEVEISITDPKGAPAENMKRYKEKPIGYVEEAEPVEETSRAPGTPSDRDADGDADGDEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNG4</accession>
    <name>A0AAD8UNG4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cutinase</fullName>
            <ecNumber evidence="3">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_578542</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364581.1">
        <property type="nucleotide sequence ID" value="XM_060505138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNG4"/>
    <dbReference type="GeneID" id="85389037"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000235">
        <property type="entry name" value="Cutinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF3">
        <property type="entry name" value="CUTINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042272953" description="cutinase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="50"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="189"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1724526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="227" mass="24138" checksum="CBDB3BE33BB13126" modified="2024-05-29" version="1">MKTQITILTLIATAICSPILLVHRAQVDTAVQLQSRQTGTMAKEYTQGGCRDVIFIFARGSTEVGNMGSTVGPPTSDGLKKKYGDNKVATEGVDYAAGLTTNFLPGGADPVGVDEMKRLLTDAANKCGKSKIVAGGYSQGAATAHRAIEKLPDSAKGKILGVVTYGDTQNQQDKGQIPNFPKDKLKLICNEGDKVCTGTLEITPAHLDYERHVPEAVDFLTEKIGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNG8</accession>
    <name>A0AAD8UNG8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_717683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367662.1">
        <property type="nucleotide sequence ID" value="XM_060511975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNG8"/>
    <dbReference type="GeneID" id="85395873"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="269"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="46312" checksum="038D484DB079197A" modified="2024-05-29" version="1">MFLVPTQHQFVDNHASLLSSGSPQLGGSRPEAAAISSLLTSLSTSMERSATEYSQSGLPSPYPSNCGDTRSEGSSADHASAAQYATQQEVRPSNYSTSATPTSEYSVYPPSARSGSFPEHIQRSYHPASNHNGGSGGMAQQASSPSLPQQDGRNHQVPLAKSDHDVPIDPSIAAPSPTYAYGQHSPYGPPPGDMSHSYQHPAYQPRPDWTGYGQHSAGPLTPASHVFPPTPSSAPPQGRPSQVYSFVPIPGAQQHKRPRRRYEEIERMYKCGWNGCEKAYGTLNHLNAHVTMQSHGQKRTPEEFKEIRKEWKQRKKEEEAARKAEDERQRQAAAAAQAAAQNGSGDPQSAPDGSSSASAYAPGRQVQLPPIGYQPSQYPAPPSAGGVAQQPLPEYNGSHMYSANYQPQSPYGQPNQSMYNSHNGAQASSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNM0</accession>
    <name>A0AAD8UNM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP11 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_615187</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366748.1">
        <property type="nucleotide sequence ID" value="XM_060507881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNM0"/>
    <dbReference type="GeneID" id="85391780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="323" mass="36227" checksum="0F6AC80DEE8E0C88" modified="2024-05-29" version="1">MASCRIPALRHLVTTSQRAFRASNQRRWAQVHDARFLATTQQPRAVVEKYRAKLEKKAQQEGVSNIDELKAAYADKIQEQKKKDALSVPGLEHLLNDEPAPAAIPTTATTTSETGEAQTQTQDKALIPGSSSGNGVKPLDEILDLPKARELPDKELTAIWRLRHASDPSSLCAVIPAATYAQMESLARQNPQFILPVPHESQGAEIHFLQWVFDAASRTATVMFTQLAEFKARGEFAQPHTTITHHTDLAAERGLVLMQGKCLEDRGVKTAHAQWLVLCLQRFYGEAEGKERAEERRKLLEWFRLGDERFSVEKLMEEAERIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPB9</accession>
    <name>A0AAD8UPB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_615874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366482.1">
        <property type="nucleotide sequence ID" value="XM_060507927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPB9"/>
    <dbReference type="GeneID" id="85391826"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="27"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="42446" checksum="B324BDE282DABC94" modified="2024-05-29" version="1">MTQTQTQTHGTCDPKFQEVRKRLQDNIDCGEEVGAAIAINIDGSDVVNLWGGYTDKERTKPWTEDTLVTVFSSTKTVLSLAILILVDRKVLSINDKVSKHWPEFAANGKEDIEIRHILSHTSGVSGWDADGPLSFEEISDLDAAAANLATQAPWWEPGTASGYHSFTFGHLLAAIVRRATGTKLRDFIMEEIVKPLDADFHFGVPDKELPRTTDVISAPMPPLSPGMGPQPGSITFKTMNPMPFPSDFANGPTWRQGDILAGSGHANAHALTRILSIISLGGSVDGKRFLSQDTINLIFEQQSNGFDLVMGVPMRFGIGFGITGEGGTAVADFLPNGRICFWAGLGGSFVLMDLDRKLTIAYVMNKLSMTGLGNNAAKSYIRAIYKALDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPD9</accession>
    <name>A0AAD8UPD9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_619679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365534.1">
        <property type="nucleotide sequence ID" value="XM_060508141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPD9"/>
    <dbReference type="GeneID" id="85392040"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042048551" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="8053" checksum="673CBD218A052E7A" modified="2024-05-29" version="1">MTITHSLCSFLWMLFCLNPSSRQPSAFSYNTRPPTSNFQPHCSPRPIPHPSLPFPSEMLHTTPFFTFRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPV5</accession>
    <name>A0AAD8UPV5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_771367</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367363.1">
        <property type="nucleotide sequence ID" value="XM_060515365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPV5"/>
    <dbReference type="GeneID" id="85399263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="26155" checksum="713642381014D569" modified="2024-05-29" version="1">MSSDLKNVTQTSDFEVDSDDAHYPSHTRLLKTVDTARVSLTAVALLVSITILGTSADALAVYDATSVPAGFMLPLWPDAFDLRPTVALVVGSSLLIIVNLVSLLFSQVQSTDIKKLRGQTLIHNSLAVAAPSVGLVASIIAMSFFYSINASITVDTLQSWSCRWSDVVMMTRPHFGTLCKQSKAGLYLSILLIPIEAIIVGMGGYQMMLERTISKTNRVVLEQRKSGSPVPSSVRDVEGDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQK6</accession>
    <name>A0AAD8UQK6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar sorting protein Vps3844 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_616085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366555.1">
        <property type="nucleotide sequence ID" value="XM_060507947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQK6"/>
    <dbReference type="GeneID" id="85391846"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041934585" description="Vacuolar sorting protein Vps3844 C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="4">
        <location>
            <begin position="277"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="387" mass="41037" checksum="A1400D6464EB815E" modified="2024-05-29" version="1">MKLSVGLAAALTGVATALSSDQPADVYLLQSKQPSSSDIPSLPRQIARLILLQRLSPEGQHASWDLPESISNEKAVSYLNEFGKAPQALFNNAASTNPSQLVVMLEGITADDAKTLQKSLATSGPAFRVGDAPSITANDMLLANDLPSVGVTAKNCAFDKAINPFAEQCWSGKSSVVRYDTKKDSSILVSLTENATLLKRLAANGEMETVIIAMPESSRNSKLRHWTSKPEELRRRQAEEVMTMTETDDHDPPAPTTPVQSTAPFVGNAERGTIPSCFGSQDACVKATGNCSGHGECLNKYAKADGQSAGKECFSCMCLGTKNETTGSVTHWGGRTCSKIDVSVPFWLFVGFGIAMVGTLTFAIGLLFSVGEEKLPGVIGAGVSKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQR8</accession>
    <name>A0AAD8UQR8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RuvB-like helicase</fullName>
            <ecNumber evidence="15">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_666878</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367202.1">
        <property type="nucleotide sequence ID" value="XM_060511095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQR8"/>
    <dbReference type="GeneID" id="85394994"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 15 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 15" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="68"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1727147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="470" mass="51295" checksum="0069B05420111AEC" modified="2024-05-29" version="1">MAAPVMTVSESKELKGLNLIAAHSHIRGLGVDGTTLEPRAASQGLVGQEKARKAAAVILQMIKESKIAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTSLASSEIFSLEMSKTEALTQAFRKSIGVRIKEESEIMEGEVVEIQIDRSVTGGAKQGKLTIKTTDMEAVYDMGAKMIDAMTKERVMAGDIISIDKSSGKITKLGRSYARSRDYDAMGVDTKFLQCPDGELQKRKEVVHTVTLHEIDVINSRTQGFLALFSGDTGEIRSEIRDQINTKVGEWKEEGKAEIVPGVLFIDEVHMLDIECFSYINRALEDDLAPIVIMASNRGNSRIRGTDYRSPHGLPLDFLDRVVIIHTNTYSPEEIKQIITIRAQEEEVDVSADALALLTKIGQEAGLRYASNLITTSQLICAKRRAKQVEIADVQRSFSLFYDPSRSVKFVSESEKRLIGNDGAVDFTVTNGHGDAMELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQV7</accession>
    <name>A0AAD8UQV7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_221344</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367262.1">
        <property type="nucleotide sequence ID" value="XM_060501752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQV7"/>
    <dbReference type="GeneID" id="85385651"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="7">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="8">
        <location>
            <begin position="267"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="10">
        <location>
            <begin position="551"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="9">
        <location>
            <begin position="764"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="11">
        <location>
            <begin position="937"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1028"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1176" mass="129936" checksum="FAB40AF0A8FBFE8E" modified="2024-05-29" version="1">MGRTFDPIADVVMTADDLKLSKHVSVGWGKKETQFQGKGAKAMRDPTIPEKVDEGLPSVNEDGSAAVSWRGDGAYVAVNSVAGDARRVVRVYSREGVLDSVSEPVDYLEGGLSWRPSGNLIAGIQRFEDRTDVVFFERNGLRHGQFTVRCADGPLSLHEKIRLEWNSDSTVLAVILSDRIQLWTTGNYHWYLKQEIPLASAFAGLAWHPEKPLRFAAATTCEFPDPLFAHELDFADWLIAIVNVAEYIFTVSRGSLSPPHDHGAVAVIDGQTLKLTPFRTAQVPPPMALFELEFPSSVLDVVFDPSNKLMAVLHRKGLDVYEWQTKGERSVKPTLKAKLELEANAITRVPLQVVFSGAAECRVLVSDGGLKLESYTIEASSISDSGATQLRPTETISSLFSREGDSGVEACAQDRSGKLYSVAGTQAPELLLGIQLSMQLPWCELHNINGRSVGIGMTRNGHLYANSKQLAKNCTSFVVTPAHIIFTTNNHFVKFVHLVDPEEMEVPGDDPEIDERCRSIERGARLVTATPTNMNLVLQMPRGNLETIFPRAMVVAGIRQLVDEKNYGRAFAFCRTQRVDMNILYDHQPSQFLSNVGLFLDQLKDISYIDLFLSSLRDEDVTQTMYKDTKRSARSFDPSTETLAPADASSKSKVNKICDAILKSLQTKKSTSLQNIITAHVCKVPPALEDGLTLVAELMQEDEKLAEKAVEHICFLVDVNRLYDNALGLYNLDLALLVAQQSQRDPREYLPFIQNLHNLSDLRRKFEIDDHLDRRAKALLHLKALDAFDELCRYTTKHALYQDALGLYRYDQARHQALTGLYASYLESNSKYRDAGLAYETLQDFAKATSCYRAAGVTCWRESLFAAQQQSPPPSDEALAELASSLADALWEGKEYAAAATIHADYLASLETAVKCLCKGYHFAEALRLIARERRVDLLPTVFDNGLVEALSSSTEFLADCKAQLLAQVPRIAELRRKAAEDPLAFYEGERPGGTGVDIPDDVSVATSRVSTSASLFTRYTGKDGSIGTAGTGVSRATSKNRKREEKKRARGRKGTVYEEEYLVNSVRRLVERVEGGAKDEVGRLVFALVRRGMTERARAVEVLVAEVVEGCKAAVREVFAVKEAEQEGGVIVGLDGETYLASGGDAVFQEHLEARTKKMEPPALSAFQKLTLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ0</accession>
    <name>A0AAD8URJ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_695395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367125.1">
        <property type="nucleotide sequence ID" value="XM_060511357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ0"/>
    <dbReference type="GeneID" id="85395255"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF7">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="567" mass="63940" checksum="F9254C05AFF1F440" modified="2024-05-29" version="1">MSNSHAETRASSRKRPAYPRKRAVQACLTCRQRRTKCDNEKPACNSCRKLGIDCVYHEFEKASFDAASLAILRRLDELESVVKGSRPLPAAPQPCLDFASSLSSSPFPTTDIDWINSFEVRYVNRDVLLNWPVWKAANVHYSSHDSPPAISPGIDSVSRPLLVSDVDVQDASRLLGIFLSVYHIFNPVLDIPTIEEHVKSTSLNGFGWDSGSCLVLLVLALGTTVDHDTVTAHTSLFIRQNEYFSRAEAFFVAAQRRMGLLLSSSGIAEAQCFFLAGVYLMTTMRPADAWKMFTRALSSCHTFQLSCRDASPGAMRLQQTIHWACFKSELEVRLELGIIKTSAWDLRYPDLFPDPPESIQSQGEPAWYFYLAEIALRRLNNRILSATCLDSQDTGEVADKVAMTLEFERQAHSWARSLPPSLRPAIDDSSDITFDFDENGQLRFILSGHLIDCLELMYWPFIYAAVHGRLGDDRDSHMLASRGLDFCVRRININKTGFFHRHHGTWLMLQSCTRSALVLIAAAYGGLHDKLPHDWKTSVADVVNLLKYWVDEVPDFRRMIEILASHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US25</accession>
    <name>A0AAD8US25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_728062</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368518.1">
        <property type="nucleotide sequence ID" value="XM_060512796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US25"/>
    <dbReference type="GeneID" id="85396694"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="34"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="57706" checksum="B265CB457F66FDD6" modified="2024-05-29" version="1">MKDEQIVGAALAEVLPKTDRYWFQQPHLLRLNLLLLIPLLSSSVAGYDGSLMNGLQSLQQWREYFGHPAGVRLGVVNAAQSIGSVLALPIVGYLADRFGRKPVLLSGIILIIVATIIQSTSINLPMFIISRLVVGFGGMFVVHPSPMLIAELAYPTHRGKYTSAYWTMYYLGAILASWTTFGCQDYQSEWAWRVPSILQAGFPLVQLCFYAWVPESPRWLVARERTTEAAAILAKYHSGIYVPSEGHTPLVRREVAEIVQTIQQEKSAETTGWMALVSTPGNRKRTLIAVCVGAFAQWNGIGVVSYYLTLVLNTVGITDTFTQTLINGLLQIFNFAAALSAAFLVDRLGRRTLFLWSGAGMLVSYIVWTACSAVNTDTGSKSAGIVVVVCLFTFYFHYDIAYTPLLMGYPTEIFPYSLRSKGIAVELFAIYGSLIIAAFVNPIGLQNIGWRYYIVFCCFLVVFFVVTWVLFPETKGHSLEEIAVIFDGPQAVENFEDASESKEEKILAKGGLHDIVHKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USK2</accession>
    <name>A0AAD8USK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_574286</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366591.1">
        <property type="nucleotide sequence ID" value="XM_060504701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USK2"/>
    <dbReference type="GeneID" id="85388600"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="277"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="390"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="169"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1726536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="609" mass="68336" checksum="32FAEB4F3D55EEB8" modified="2024-05-29" version="1" fragment="single">SEGPRMGDAAFAAYLTSTYNLPAIKEPKTYSLDRPLNEYFISSSHNTYLMGRQVAGLSSVEGYISALVRGCRCVEVDCWDGPDGNPTVNHGRTLTTSISFQETMTTINKYAFIATKYPLWISLEVHCNPAQQAEMARIIKETFGARLVTAPLDPSSDKFPSPEQLKERVLIKVKRPQPPPEPTKPAESTGRRRGNSLSSPYPKPVQLDNSIVPSQSLPQSPILSPSHSSRRLVSKSRVNTITEGEVQDALSSSTSDNDSAGERMPPRRSSNKTVKVLGDLGVYCAGLKFGGFDATEAKAYNHIFSFMESSFHKNSRSKEEKRAIQLHNMRYLMRVYPDRTRITSNNFNPIGYWRKGVQMAALNWQTFDLGMQLNQAMYESGTDRSGYVLKPKELREIKVMPPGWEGHHRERQEVTFSIDVISAQQLMRPNGMPNNKTVDPYVEVEVFHSSDKRDKKDTDAEGSLSDTPLMFRTKIKAGNGFNPIFNEKFTFKVTTKFPELIFVRWSVKLSHNGESYNDRQPVATHTAKLNGLKRGYRTLPLFDHNGEQYLFSTLFCRVNIDSVQTVLLSNNDDVESTGTSKSRGVGRVFNTFGTRSNNISPKSSMEKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USN7</accession>
    <name>A0AAD8USN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_101830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368833.1">
        <property type="nucleotide sequence ID" value="XM_060501028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USN7"/>
    <dbReference type="GeneID" id="85384928"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17618" checksum="DFFAA2E13CF70A04" modified="2024-05-29" version="1">MRAATKKNPAIHYLSHAPPPANAHSKRREEKKSKAQAPATSARRVPKHHRRQKAATAPAASSSSSSSSSSSTTSCSCCTCTLYQQRVSSLRLIPHHSLFFPPLVQIFERDQGVTRGKERERKKKKEKKTLPTPTTKQRLGSQPHQTRGPHFLLIHVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USS4</accession>
    <name>A0AAD8USS4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylserine decarboxylase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_750832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366514.1">
        <property type="nucleotide sequence ID" value="XM_060513970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USS4"/>
    <dbReference type="GeneID" id="85397868"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF13">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="49631" checksum="5274EE5E15822C7B" modified="2024-05-29" version="1">MPPKSSPPDPAPFPLSSKVDPWIQTSLVESIFDGNLTLLQEAVNAATAQDIPQLHDWGIKDADTFLRFLSAMLNWVPSEVCSGKLIYNTFCVLYFILDQRPINIPPYSTPITPNAIGQAPLPLSQWTIDFANKVGSWMDTSNSINAAAIQTFQDSPRYNYDEAIVPFGGWKNFNQLFARLLKPGMRPISASNPEDPDYNRLVVYPADCVFDGAWPVNQNNDIMIKDVPWNIKDLLSGSQYAEEFEGGTFMHAYLNTYDYHRQQAPVAGTVVEANVIKGLAYLQVITDPETGELKPHRSYTSPGAQATKKLGDGENSTLSMPDEAGYQFLQARGCVIIKNSLLGYVAVLPIGMAQVSSVNLVWQPGPGEQYPIQPNVKINKGEEISHFEFGGSDIILVFQQDAQVHILGAQGKAADGTPTSKQKYLVGMPLGYSTKGLVPSSNGLRNGATNGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU58</accession>
    <name>A0AAD8UU58_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_749821</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367829.1">
        <property type="nucleotide sequence ID" value="XM_060513822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU58"/>
    <dbReference type="GeneID" id="85397720"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.150.10:FF:000004">
        <property type="entry name" value="Chorismate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="408" mass="43811" checksum="64793F6A4B961AA5" modified="2024-05-29" version="1">MSTFGNYFKVTTYGESHGKSVGVIVDGVPPGMALTESDIQPQLNRRRPGQSSITTPRNEKDRVVIQSGTEFGVTLGTPIGMLVQNEDQRPKDYGNSTMDMFPRPSHADWTYLEKYGVKASSGGGRSSARETIARVAAGALAEKYLREAYGTEITAFTTSVGNCHLFPPTPEHPSPSTNPAFLSLLNTVDRKTVDQFLPVRCPHEETNEKMIDLISDYKARDDSIGGTVTCVIRNPPSALGEPCFDKLEASLAHAMLSIPATKGFEIGSGFGGCEIPGSQHNDAFIKAPESELQADAQRMGIPRSKLTTKTNYSGGIQGGISNGAPIYFRIAFKPPATIGVDQTTATYDGSEEGVLAAKGRHDPCVVPRAIPIVEGMAAIVLLDALMAQHARQMTKSLLPPIKRENGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU76</accession>
    <name>A0AAD8UU76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_571657</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367893.1">
        <property type="nucleotide sequence ID" value="XM_060504429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU76"/>
    <dbReference type="GeneID" id="85388328"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="23"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="55614" checksum="B7E10276AF3FFAED" modified="2024-05-29" version="1">MLLASTAVTAAPYNTFDGPGFPACNDVAAVHNATSVSDIQSLVKDAIASGQKVRASGKGHMWYDTMCSDDANTVIIRTEDVNSISEFDLESGSVVIEAGVTFLQLAEYLHARGASAGYTLVNWNITLAGCVAMGAHRSSIREDSMVAAGVLELDIVDGNGELRHLVRDNNDDTWLAASTSLGLLGVIVRMKFKIYPDFKVYAQQKTLEESEVLDGDIYGMIAPYATANFWWWPYKRKFHHRYYDVVPTNTSDQQGFQNTFSVTDLEGTTARTLLDSGRYLPTSNMLAEEIFFGLWSKPNFREKTTNQPIEEWPVYGWNYDVLIGGLYPDQRPLWEVGVQGYTLELAFPITQANAMLKRVRALFDDEAKKLIVMTSTYRSGINIKFGRPYFDLLGQVTYGTADGADWSKGVIMLDFPTFRPTVGDHSRFNEPFYHNLAKVLIDEFPCRPHWTKNTREVFAQAAKNIDPDHIVRFKAVREQFDPNGIFKSVVGEAIGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7W4</accession>
    <name>A0AAD8X7W4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_644878</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000281">
        <property type="protein sequence ID" value="KAK1703480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357293.1">
        <property type="nucleotide sequence ID" value="XM_060509790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7W4"/>
    <dbReference type="GeneID" id="85393689"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF7">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1703480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="46771" checksum="4E076F489372CA12" modified="2024-05-29" version="1">MPSPLKILISGGGIAGGCLAFWLVKLGHDVTVVEWFSTLRATGLQIDLRGHGIEVLKRMGLEEGFRAKSVPEQGLQFVDSSGRRRGHFPMNHSGSGAQNFTSEYEIMRGDLCRLFYDATKGRAKYIFGTSVENFDQKNGGVDVRFKDGKTEHFDLLVGADGQGSRTRKMMLKSEASDGFYPLRGIHASYFTIPRPIEKGEKYYSTAYFATNSRIVMTRRHSPEAIQAYTFFTSHDEEFQNARRTHGKEVKDVVAKAFKGAGWKVDYFLDAMMDSQDFYCEQIGLVKIDHWSEGRVALVGDAAYGPSSMTGMGTTSAIVGAYVLAGEIGQHCGSERGQDGIETALQEYERKMRPFMDQVQEGITDDAFVYKLWPTGPIGMAILYWIIGIVSFFHMNLGKWVLKESAVKWNLPDYKELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9P7</accession>
    <name>A0AAD8X9P7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_589335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359709.1">
        <property type="nucleotide sequence ID" value="XM_060506226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9P7"/>
    <dbReference type="GeneID" id="85390125"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF7">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="273" mass="31774" checksum="7B299CB3DEEE9642" modified="2024-05-29" version="1" fragment="single">MKTATPLPLEKLSSPPHGNHTDTSQDGTAVDHENGEEDNAPTDLIVPPPNGHCACIPINASADPELLEVNVWQAVNEVLSVPWRTSTEAHVTEDAKGKDTIVRALIEGWDVAAKFQPLSDLWIKLRRVDELCFQACPRTERLAILWMVSLQLRYHSNPTTKRRDKLPPWYWKRPSQKIPHSYAINLFVWPGVRERFVFEQHKYCDNQFWKSFARNFRLLWPSDFQHTYAKNFTTGLYEMLQSFEQSISDINIWTMTEDFFNRYPEFRADIPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAK2</accession>
    <name>A0AAD8XAK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_756002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HyuE racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
        <property type="protein sequence ID" value="KAK1716694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360624.1">
        <property type="nucleotide sequence ID" value="XM_060514689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAK2"/>
    <dbReference type="GeneID" id="85398587"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07569">
        <property type="entry name" value="DCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052186">
        <property type="entry name" value="Hydantoin_racemase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053714">
        <property type="entry name" value="Iso_Racemase_Enz_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047:SF6">
        <property type="entry name" value="CN HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28047">
        <property type="entry name" value="PROTEIN DCG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="606" mass="65379" checksum="0CD6B164B839612C" modified="2024-05-29" version="1">MSSRKLRVAAAQMGATHYNDTRPKTLNRMISLLEDAAAKGAQLILFPEAAFTTFFPRHLINDPSELDSFFEHGDVATQPQTKPLFDKAIQLGVDISVGFAEKADNGETFNSCIYYHAKSGSILSKYRKIHLPGDFEPFADPDATNQLEKRYFKPGDLGFNAFRVPDLTALETAPERGDPIFGMMICNDRRWAESWRVLGLQGVEVVLCGYNTAGFAPHLWGTSASMDPDEARSKALFHHKLVMQAHSYTNACFSISAARCGLDDGKYDLIGGSCITGPEGELIAEASTTEDEVVYAEIDLAECRPGKERTFDFARHRRVEHYARITEQTGVVEPPKLSSTAENHHGAASNDIAPQKSQKKIRILLINPNSTRAMTDACVAMVESQLPPDVLVTGFTAPRPAPSAIEGSFDNVMSAAAAARAVLPLAATHDAVLVACYSDHALIRMLREELPCQPVIGIMEASLFAARTLGGRFGLIAVSERSRVLHEDSIHHYGFSTSCAGVVSCKLGVLDLHEKSQDEVMGIMAAVGKKLVEEKGADVLLLGCAGMTPLKGAVEAAVGDGVQVVDGVLAGVHHLVGLVRMGGATAKRGVYKSSGDGRKARGQDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB97</accession>
    <name>A0AAD8XB97_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_755724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360922.1">
        <property type="nucleotide sequence ID" value="XM_060514656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB97"/>
    <dbReference type="GeneID" id="85398554"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="176"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="954" mass="107951" checksum="EDF92C3617C3C1C9" modified="2024-05-29" version="1">MSSHEYLDLCHEVHNLFLGHLKRKNSESLRFATRETPKSVLSPHYLRFFFRSLIGGEAPKGRRFSITEDEFVENVQGRELHKFLAILVFAGCRIEAARNFTEKLAAAPKWPPPEDGEISRRVCSLPADRQSLTEFFDGDEATADKFYGSQALFCTVVLRQREETTIQDGDTQRLPYVEEELLGSGSFGRVYKVKIAKGHFEDRRRNDNRERWVARKDYIVRSSSDSDVESREEGEIMKMILSLSKTCENIMENLGTLNIEYPTGASPAPYSLFMPLAVCDLGAYMKKDGSNAPKTAINRAGFIRSAIGLANGLKFLHQEMQTPGLDRIVCYHMDLKPSNVLIFRESGNGDGAGPRYIWKLSDFGMSRVKIRHHTSREEEKDIAKWFTKRRDMQQRTMSGTQNRRGQGTYLPPESFREGKVMNTRSDVWSLGCILSVLFVYLEGGKRAIDNYETNRLKNRRGIDASYDVFFHVKLFGHTSVHSAVKNAHKQLIHKAAARSVKEHQAVRTMLNFLGSKVLKINQNKRCSAKEVENMLRRTLDAYEEIDRLESSSESLRQPKSSMEQIVQRWRVPRDNSDVFKGCKVSPDGSIIAYWSDNKISLFTPSSAPNADGDVLNILREHSLESMGSTSRFWKAVCLTNRHLVATTTGNIFNCYIFDLGQGAAVDSSAQNYWHIRLPTVPEVYIMAMSTDQQNLVFVVENQEDESLSGSVFHVRIEDLIEMGSISEGHGVDQSGSNLLGRFIALDWPAEDVISLSLTEQNRCYAAIRPYLREDGIYHMPIVAYSLTTRDIEEVFIEPRSQESNGSSLFTTFAGLHQRAACIAVFQETRLFTVDLLANSCNSPKRRSRYPKNIEEYRLLRVMADQNDDTIFALGIKPDGGRIRLLEITIPETRDPMTVRELAQLPSLSENDEFTGTIVGDDGSRHILVTALVGSHRHAVFKINLPSRHPASSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBF4</accession>
    <name>A0AAD8XBF4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_593788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000226">
        <property type="protein sequence ID" value="KAK1706420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357820.1">
        <property type="nucleotide sequence ID" value="XM_060506664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBF4"/>
    <dbReference type="GeneID" id="85390563"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1706420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="507" mass="56910" checksum="72B51A1760E82D0B" modified="2024-05-29" version="1">MTTPVAPAHSNGAASRSSLACLSCRSRHLKCDGKRPRCDRCAAAAKECNYAPSRRGGLDRVALAERRKRLAVVNSVGNSSSESPTSLPSQQSSDSQIFGQDSLAELNHGLGIFDDGSLENQIPTSVPPVPSTIRPDDPKHDALTNAYYTDFHKFHPFLLPQEQFTRFRQDPNWIGRLRPLISTMHLVGHIYTTRTWSSELQDDVESQLSEPAPIDPVIVQCRLLYSIALFWYSHKMEAKYQMDLAVRLALDLRMFQKEFAATHGAESTMLMECWRRTWWMLYIIDAYYAGTLGTMNFAVVDVDSNVELPCMESEYESGDIPESQSLEEFDLREFASEDTSYSSFAYLIGAVRCAALAISTTPRLVAREDSTRMIEEADSIIDGWSLLLPEDRRHVMSKTGEIDELMFQAHLLVNVASIGLHRPLSDLRFNPVEYISSCAREPPQENLETELINVHTVRVLRAVQAQLRLLALPTERFHHTPFTTCMVSEGTLALLSACSFLLKGNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBQ4</accession>
    <name>A0AAD8XBQ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">galacturonan 1,4-alpha-galacturonidase</fullName>
            <ecNumber evidence="12">3.2.1.67</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Galacturan 1,4-alpha-galacturonidase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Poly(1,4-alpha-D-galacturonide)galacturonohydrolase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_761805</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1-&gt;4)-alpha-D-galacturonosyl](n-1)</text>
            <dbReference type="Rhea" id="RHEA:14117"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14572"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58658"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.2.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.67" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360416.1">
        <property type="nucleotide sequence ID" value="XM_060515198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBQ4"/>
    <dbReference type="GeneID" id="85399096"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047911">
        <property type="term" value="F:galacturan 1,4-alpha-galacturonidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF6">
        <property type="entry name" value="EXOPOLYGALACTURONASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 16 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042266839" description="galacturonan 1,4-alpha-galacturonidase" evidence="17">
        <location>
            <begin position="20"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1716022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="51487" checksum="748C098708BC77BC" modified="2024-05-29" version="1">MRFSRSLALFGAVAGVVSSYGIELPAGVPRSLEEFRDKHPYTPPSQGCGRKTFTIRASRNATDDVSEELKKGLQEANNGGTLYLPKNQTFVIAKALDLTFLNDIHVRLEGEIKFTDDVKYWQTNAFTHPFQVSPRSRKWGGKDIKIYGDGVINGQGQRWWNEFNSGIGSILNPDNKYLRPILFYVENTTNLEVEGIHMKDSPCWTNFVVGSSNIEYRDVIATAITNNGSIIPKNTDFFDSLDVQDVKIERVWVNIDDDCFSPKSNNTNLYVNTMYCNGTHGQSIGSLGQYAGEMSYVKDVHIENVWMLNGDYSGARIKTWAGPNVGYGFVDNITYKNFWVARMDYGVILDSCYFNINETTCEQYPSGMNVSNVLFENFSGYTSGIYGNAVAKLTCSTNPDAVCHNIKFKNFNVTSPCGGEPVIICDGVDGGIDTPCVSIDSDEAKAALAAKCQTPLAPINEKPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC47</accession>
    <name>A0AAD8XC47_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_721901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361837.1">
        <property type="nucleotide sequence ID" value="XM_060512418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC47"/>
    <dbReference type="GeneID" id="85396316"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056693">
        <property type="entry name" value="DUF7791"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25053">
        <property type="entry name" value="DUF7791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="172"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7791" evidence="4">
        <location>
            <begin position="427"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="783" mass="89469" checksum="D2AA0045AC492098" modified="2024-05-29" version="1">MAELAYISLAINLLQFAELGAKLVRGALERYKSADGLTIHDEMFIADARRLRHLAGVILNNESDTTKTTESPILRSIAQRCTEDAAVLIEILDALKSFEQAIRCMLKEHKIRELELRLGSLRRELQLFLTHAAGAEIDDLNEEQQHAKQEAIKEKHRATFDWVFSHDDTLFPQYFCRRGKPGSGKSILMKFLVTHPATRVKLGAWGNGYTMVIASHYFWNAGSSMQKSQRGLLQTLLYEVLRKVPSLIDRVCSRRRSALQHKLMESWGMEELLDAFALLATQTDLSVKFCFFIDGLDEYTDRAKRYDNTFEDVGITTTGTKLRPTEDLLRVIQDLASSPSIKICASSRPWDAFLDAFGAQPWQLRMEDLIKDDIRTYSLKNDLAKGDTFRELKTDLEEYFQHMIESIDPIYWESMARILRIMIESAFEFLEQEAESARYALQMKVSSILPENVEIMKKRLNARGKDLLYVTFRPAKKPFLQYQVDFLHRTVRDFFIDRDVIEETKAKRKTSHFNPALSLCRIMLALVKTVSYAEIAVDYNEAYLNNRETADNRSQCLLDDLEDMFNLLDALDHTNTSNARDKSVHWTNFRDIPKGNFKEKRQKSFLASAIQARLPLYAKHKTNTNLDQAKKKMGRPLLDYALRPTTVTPLELPTQEGPVRAMVESLLQNGADPNQTIELYGGKTPWQSFLSVCYRHSLQADKPNLDADEITDTIVAMLLSGADPKVRVDLQGGGKADILGVAQRLELSRAKIERIKSVMHIGGNSKQLGFIGTLSSWWWKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCC8</accession>
    <name>A0AAD8XCC8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_745152</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358660.1">
        <property type="nucleotide sequence ID" value="XM_060513180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCC8"/>
    <dbReference type="GeneID" id="85397078"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="136"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1709749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="393" mass="43923" checksum="2AF803A4F4C1E46C" modified="2024-05-29" version="1">MARFNPFARRRQDTTTLPTHRKSSHETKVNDRWHGQDYSMAHRPPFMLWLKVTWLDILTMIIMGVIALVVFRAHPPAHRTFPVTFDNGEVVYPQFAYPHIPQYIPSHAATALGIGVPILSILLCQIRVRSFWDINNGIMGLLYSVIGSTVFQVMIKWLIGGLRPNFLEVCQPDISKASQPGGNATGLDGTGYGGIMWTSDICTREMDGTLSNAMESFPSGHTTAMFSGMVFLYLYLNAKFKVFSNHHTPMWKLVLVYAPILLATLVGGSLTVDQSHNWYDVLAGAIIGTVFAFSSYRMAYAAVWDWRINHIPLHRKMPLEFNLEAIGEGGTVVTRKAGWGKRRGDKGNGPDRMASRTRYTTGSRDTRGVGVPRKAVASHHSRGDRRPSGEDMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCL1</accession>
    <name>A0AAD8XCL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transport protein particle component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_429851</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362362.1">
        <property type="nucleotide sequence ID" value="XM_060503039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCL1"/>
    <dbReference type="GeneID" id="85386938"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="25373" checksum="5008F8BE093B0E19" modified="2024-05-29" version="1">MSFESVMPPYNATDPSASFLNSSCLDFLLIELVPMAFRVTRDLEAAPTDANGTSGGGAAGGGASADALSSVSHSQGGGADGGPAPSSADGAAGGSTVRKLDEDEERDAVFYRLETLGYRVGQGLVERFSRDRPRFNDTLDVIKFVCKDLWSLVFRKQIDNLKTNHRGVYVLTDNSFKPFSRMSTEAGGQAVVRAQPFLWFPCGIVRGALAALGINATVQAETNELPAAIFQIKTLPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCQ4</accession>
    <name>A0AAD8XCQ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_637231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000135">
        <property type="protein sequence ID" value="KAK1713775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359828.1">
        <property type="nucleotide sequence ID" value="XM_060509292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCQ4"/>
    <dbReference type="GeneID" id="85393191"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="694" mass="75344" checksum="65F3A8846BC7803D" modified="2024-05-29" version="1">MDVDHRTKGPRACTTCAKAKARCISGPDGSNKCERCHRLRKPCGSQTPAPPRAKKEPKPTKVSELEKRLDELTTQLSATTQQGGVGGGRHSNSTTEVATTVANGTVVGSANSPLPPSGSIAPASAKIPINCDHLFPPEEVIGGGGEGGWSDASPAPSASTADDHHTVGSSQADNNGASGMGSTSTTTNESPWPLNNEQSKVLKVFLDDMQPLYPFVIVPPHMSPTQLAAERPFLWKGIMMTACHLDATKQVLLGEELLQDIVQAAFMKPKKSLDVLQGLQLLIAWYHYNINSYQLTNLLFLARSMCVSLGFKDSPMQLAERGGKGTGLSISFQKPESEARKVQTPEQISAQLELMRAFAGCYYLNTLVFTTNKRPDAFMNTTYLETCCRQIEEAAEYPSDALLVHLFKIQQLAQTISLTLGTESTSFQSLQLPLTMVVQSFQQQLDIFKTSLPEHLKDNVGLLAHISIAQVLLYEIGIPEAQGPASFISLTERLELLWGCCSAAKQFLEIRFPLNHLSLQPRFTCLSSSDFLYVFIVCLKLMTLDQVPGWDLPLVQKHLDLGGVVESQVAHLEVFVAHRSGKFRRAAADAAAARGEGEATGPATDVPGPKVVDPFVRLTEMLRYFKDIVKGELCGLKSQPAIQEPIQLPANLSDGTQAMIRDLDASFWTGVLGEDAAGTWDVGSMFPSMDWTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCX2</accession>
    <name>A0AAD8XCX2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_588398</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360128.1">
        <property type="nucleotide sequence ID" value="XM_060506136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCX2"/>
    <dbReference type="GeneID" id="85390035"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000012">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1714985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="46262" checksum="9455EAF199381982" modified="2024-05-29" version="1">MAPGTISPGLHHGNQDIDLTSSAIEHKLEAIPNGKASNGTKPAYQELDASKLIYTRTQNPRAVPDPASANAGSETIATDHMVAATWKVGTGWSTPELKPYGPISLMPTASVLHYATECFEGLKVFRGFDGKLRLFRPDRNCERMLMSSTRIALPSFPPAELEKLIIALMAVDGPKWLPRERPGSFLYLRPTMIGTQPQLGVQAPSEAMLYIICTYMPVMDSPVGGMKLHTSPEDMVRAWVGGFGYAKVGANYGPSLLATVEARSRGFGQILWLYGQEQYCTEAGASNFFVVWKNKETGRTEIITAPLDDRLILDGVTRRSVLQLARERLGDSVDIVERRYTIDEVIQAHEEGRIVESFAAGTAFFICPISLIHHRGKDVNMGMGGEGVGGEYTLQIKNWMKDIMYGGEQHEWGVVVQEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDC1</accession>
    <name>A0AAD8XDC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_589446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000139">
        <property type="protein sequence ID" value="KAK1713354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359680.1">
        <property type="nucleotide sequence ID" value="XM_060506235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDC1"/>
    <dbReference type="GeneID" id="85390134"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="643"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="749"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="783"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="813"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1713354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="878" mass="99114" checksum="0482BF28B961AB7E" modified="2024-05-29" version="1">MSGKVETVGEEPTPAREEDIEKIPARVDNPEQKISDQISHEKLEELAPNGEGEYILERINEMTEEDALEIIEESVEFFKDDWNFPSDMRERMKKLLEGPKKYGENYDRDLRIDAVMIRFSSPYPGVRAVAEILDDQSVPIETFRAYFLGIGWAIIGTFISTFFNSRFPAISLSGQVIQILLFPCAKVLEFVLPDWGITVRGTRHSLNPGPWNFKEQMFATITYNIAIYTTNSYGMILVQKSPVYYGLDFVNFGYQLMLTLFVQLMGMGFAGYLRRFSVYPVKALWPTILPTIAMNRALTRPEPRENINGWTISRYKFFYVVTICMFFYYWFPGYIFTALATFNWMTWISPQNVTLAIITGSSLGLGLFNPITTFDWNVATSSYAALAQPFFATCTMYIGAILGGVIIIGIYYTNMYNTAYLPINSSSAFANDGTPYVVQNVVFNNQLNETAYQEYSPPFYSAGYLLTVGANYCFYPIYFLYIMGNQWKTISQAYIDFYKGLRHGKGNYEGAMDIHSRLLAKYPEVPDWWFLIILVAAIVVSVIFLNIYPLGTPVWIVFLMIAINLVFAVPLSFLSATTGTNLGLGALIQVITGYLLPGNTNAFLFSQTLGSWALAGYGDNYVQDQKMAHYAKIAPRAVFRSQIGTIIITCFVAVATQNFILENVKGLCTPTQPSRFTCANDGAPLYTNSLMWGLLGSERMFVSFYPILKWCFLFGTLIAIVFLVGQGYGPKYLPGVREKLRLKLSPKTFARLDKTLFPFVASLLWLNPVLVIQGIQHWAPSNLSYKTPGFILGYIFMYWLPRHRLAWWEKYNYVLSAALTAGVAVSALVMFFAVGYNPIAFKWWGNTVSGAGVDGSQIGILPIPERGYFGPEKGSFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDT6</accession>
    <name>A0AAD8XDT6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_626035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363532.1">
        <property type="nucleotide sequence ID" value="XM_060508532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDT6"/>
    <dbReference type="GeneID" id="85392431"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05918">
        <property type="entry name" value="A_NRPS_SidN3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="599"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1124" mass="123094" checksum="577021125B80C268" modified="2024-05-29" version="1">MEPRRLHFIKDSVVHIISVLLSQPNKKLASLSVMNHAETDYVSNTLSNRTSLRVPGAELLHSAFERIATSTPDAIAIDFDGKEIVSYALLDRLSNRFAQTLIAHGISPGDLVPLMLEKSVDMMIAILGVMKAGGAYVPLSPDNPNERNGFVVSDTRSKLLVVHPQHAEFGAYVKQLYSVETLTMPSHGTLSTVSSDGSDANIAPITRTTPDNIAYMIYTSGSTGMPKGVMVPHRAAAAAVTSMAQVEGRFEGTWRTLQFANYVFDASVQDFFNTLSTGGTLCMAPTETLLSDIAGCINRMDVRQAIITPTVAKLFSPEDVPGFETLIVGGEPLTPDVVDVWSPHCKILNVYGPTETSMVVTTKSIESSSGVTSHRIGNIGAPFSTAMAFILSPDGETFVPYGAVGELCIAGPQVTDGYMNRLDLTEAAYVDSKSLGMRIYRTGDLARWLPGGEIECLGRKDNQVKVHGHRIELGEVENSIRRSGLVKDTVALAATIQGKAHLIAFCIFDEASAAIGPTGVQDPSTFRDSLAELRENLSSLATYMVPKFVVPMDAFPKLPSRKVDRKALKVLANELDREYLAQCVLESPGENHQVVPVQAPSEEILEIVWADIFSIPQNDIGREANFFTLGGDSISAISLTGQLRRVGYSLTVLDILKTPKLKDMASTLRKIEARGQVVERSFEVPPSIKVAAQEVGIVWDTDVDHVYPCPPGQAEFLKQGSRESQMWALQTVRRMTADVDPDIWIEATTRLTEVNEILRTTWIDTPEAGWVGVVLDGSELDITKVALNSESESSSFIEEFWQARFEFGRPFIKYAIIAYGDASWDLVIKMDHAVYDGTLLRVFDDHFGAILRGESVPPPVEFRDFSQHVFEEDKTASLGYWKAKMDGLGPVNQQLHGRDLAAAPSPKITASLRREIVTTDIDQAASRLGVTPSIIFQGAFSLWLAAATEATDIRFDYLLSGRNVALPDPQSINGTLANFLPFRTFVGPKELVHDFLAKLQDDFWDVTENGLVGLDDIYGVAGLSRETHGNRVLFLSQPFEPAAKDDPNGRYRWLVMAKSKVRMYQPYALVVEVSKSLGDRHILKVMYDDTILDVTVAESIADGIVALVEVLTDATNANLALEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEH5</accession>
    <name>A0AAD8XEH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RPAP1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_621946</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RPAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364854.1">
        <property type="nucleotide sequence ID" value="XM_060508300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEH5"/>
    <dbReference type="GeneID" id="85392199"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013930">
        <property type="entry name" value="RPAP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08621">
        <property type="entry name" value="RPAP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPAP1 N-terminal" evidence="4">
        <location>
            <begin position="89"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1 C-terminal" evidence="3">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="426" mass="46380" checksum="75B40FC685CABD2B" modified="2024-05-29" version="1">MGPMMLVGDIVEKETAPAKPVVFDDIDAAPTGFPAHKKRAARVSAFKQQRQGKPTTGAQAAAATSSIQPKSSDDVAADSQKSFEAAERRRIDRENRQKLEDMSPEDIAQERQELLNSLDPSLIQRLLGRANIDEQHGPNPFDPPADDTKREPPAPAPEIKIEDTSAPPKPKPAPKPTSAPKSVSFADEEDEPTAKAPPKPPHTHEDKAPAAPPADLFPLNDQPDKTHFPQAPALPDLDPSHPDFLQTLHEKFFPNLPADPSKLAWMAPIPTVDSPADRESPYYPGQSSLPIAALRFDFKGGLIPPRLSRSIPTSKGLHHHGQAPEAAGYTIEELAIYARSAVPAQRCVAFQTLGRILYRLGKGEWGNGEEDSLGRGIWSSVQEGRVLESLSEAAIVDGGHRGSRAYATEALWLFEKGGWREQWSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XER4</accession>
    <name>A0AAD8XER4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_730662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365109.1">
        <property type="nucleotide sequence ID" value="XM_060512852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XER4"/>
    <dbReference type="GeneID" id="85396750"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="116" mass="12668" checksum="4F80A59F3570B09C" modified="2024-05-29" version="1">MDGLAPPVFTTLLCFGYGRSDLLNGRQPATTMRNWRLEAGGWRLELGLSDKTRDGERGTYPPLGVMKEGTLSPAASAKVGRLQPAGALTAAPETIGEDSQEIYHQQKRPPKKHCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEX7</accession>
    <name>A0AAD8XEX7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_580043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363881.1">
        <property type="nucleotide sequence ID" value="XM_060505305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389204"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="2">
        <location>
            <begin position="605"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1307"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1316" mass="146959" checksum="4399C2AB1CA1E599" modified="2024-05-29" version="1">MRAVLPGRPRSGLQALATGFWDSRHFNVYITGSAITILGDADTIIQTIYDDDPSHLQAAAFDESSGKITTCTESVIRVYKPFGQSENALKWGLQSSWPVPDRQHATKGISLSWGGNEELLVAHSALYLYSTADEPEQLWNKQLPNSVKLAEISYDSAYIACVGAHDCLVKVWRRLTYGAEDVRFDLAYLRHPDLVASLRWRKPLHTDQTVENVLFTTCADNLVRVWTGTDTHAFRHMNLWGSVDLASSFRDLGLGSTRPTAPLVTFVIDGREVSAATELAVQRCSVKDKPRDAALERLISLANNSAELCVASDAIGNMMIFAFEDVGSKTRKSQDAIRVTSFKSHTLDFRSDQYVSIQSYCDRATGRLHVLIHDFDGQIQVYDADLAEFLSAENKSGRLARRCIWAGHSAPIQKMVRNFSGRAVVSRTEKGESIVWTHSETSQTSLSCQSVIQGNAHIHRICVLRKGRFVIFLEHGKISLWDCRHQKAILLASQSYEISGKPLCLLILPRHQVEEYAVAHIATVTSEEEGLVWEVNLPRYSSQGADAHANGQEKTSISEFCRFKLKDAEGIAYMLPVDPAGSTPATSGFLDVFARDIAVSYTHAGRVDFWTARVGNTGKSVGWLSTSSAETGLVEPALVSGSTLKKAAIVDSARSQLFIWDIGGARLEFTQDYGRHNTIQDLDWTSTPDSQSILAVGFQSKVVLLSQMRFDYLNKGPAWAAVREISIREFTPHPIGDSTWLGDGHLVIGSGNQMFVHGREYDLSGSLINSLQLPHRKNGVWDLFDAVQRFNGPLPVFHPQFLSQCILAGKSTIVRTILMSLHKTLKFLIAGETVDDYLGLEPAVFYSSGASPTQASESQVGSHFSLQVSADETDSEEPFSEETALAINGRLTKVGLQQLSGHEQIQLADIVECVGIVEKQRRSLDENGARFMLFFRQHGLRKGRTSEIQMSWREINWAYHSNSQDILTDFVSKQCHGALRWEDARESGMFMWLTDRNALLAQFELVARNEYTKSEMKNPVDCSIYYLALKKKTVLQGLWRMAHWNREQGATQKLLSNNFEDPKWRTTALKNAYALLSKRRFEYAAAFFLLADHLQDAVNVCLNQLKDLQLAVAIARVYEGDRGPVLKKLLEEEVLAVAAKEGNRWLASWAFWMLNRKDMAVRALISPVYTLVETPCSPNMQSKLFLTDDPALVVLYSQLRQKTLQTLRGASKVTPRVEWEFVLHSAKLYDRMGCDLLGLDLVRNWEFLKPAPPITNGLGGEVNPLKLLRRRSSLVVADLPVSRLHSEIRPSGQGKQSTPTVFHEPDSSSLLDSFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGR5</accession>
    <name>A0AAD8XGR5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MYND finger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_719034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365741.1">
        <property type="nucleotide sequence ID" value="XM_060512138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGR5"/>
    <dbReference type="GeneID" id="85396036"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="550" mass="61943" checksum="CB67B1FA606AD00D" modified="2024-05-29" version="1">MTELSSGIEVRGEKGGAKGRSIHATRRFEPGDIMARFNNPAVVLPPGPRALEYCNQCLNQQQEDVPATEKLRACTGCKTVAYCGPACQRANWSVVHKVECKAIQRLHKTKPADQPNWVPTPVRAAAQVMLRPKVMEKFEELEGNVESWQGIEMVKLQLQARGVVMCLGGDENSTDLLESAFQVLCKLQTNAFSVSEDETDGVYLDTTLAMMNHSCSPNAMVQFDGRLASLRAMAFIEPGDEVEISYIDETQPKSKRHENLRSYYFDCKCFKCIEDLDEYQIAQKDPRVARLNELSVTPDIERFKHPQVADKDGLRQAIEVQKLLEMFPVQLRNMEPAAKHKWLRKAYKSASWFPTNGRWAIEPFAQLVDEAAVYFGKTLGNHECALAIACLTAYEVEPYKHPIPFHVERIRGLSAIATELSQTAPEPEKLVKLARDMAAKKKFSAAGVRVLADLDQVSMCQMVLSLINSYKDRTPTVDWDGIMFRWMVAEIESLPGRDRENSLINAWIMDPKGMDQFFRYALVEPLKALSELGKAVLEVDLGEDRDLSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGX3</accession>
    <name>A0AAD8XGX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS allantoate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_578688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364448.1">
        <property type="nucleotide sequence ID" value="XM_060505155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGX3"/>
    <dbReference type="GeneID" id="85389054"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF26">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09470)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="85"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="59264" checksum="1088F8E1E16B6DC7" modified="2024-05-29" version="1">MSTNLSSEHVDLQPSRPQSIGHGIDEFKPSAAQFETMEEGDPQKFKLSKAGGDVALALFDNVGDVHDPIDPEEERRLVRKVDWMILPYISVCYVFFYIDKTTLSYAAIFGIQSDLKLKGTEYSWLSSIFYFGFLVWALPTNFMLQKFPIAKYLGLNIFAWGTFLMLQAAAPNFGVLAALRAISGAAEACADPAFMIITSMWYTRREQPIKIGLWYTANGIGIALGGLLGYGIGNIKGALASWKYEFIIVGTLCCAWGIVIAVFLPDNPITSSKLTNREKEIIVERLRENQTGVENKTLKLYQVREAFADYKLYFFFMIALLQAIVNGGTSNFGTLIIKGFKFSTLVTAVLQIPYGAIIFIAILACVFINDRLPPNNRCFVLVLFLLPNVAGAFGLRFVPDDQQVGRLICYYLTGSINASFVLLLSLQTANIAGHTKKVVTSACLFLGYCVGNIAGPFFYKSDQAPKYELGIWSMIVAHLLEVLVVIALRFLLKWENDRRDRVQGEVAEVDLDATAFGDLTDRENLNFRYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHP9</accession>
    <name>A0AAD8XHP9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_574014</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366806.1">
        <property type="nucleotide sequence ID" value="XM_060504673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHP9"/>
    <dbReference type="GeneID" id="85388572"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="532" mass="60184" checksum="51762125884387FA" modified="2024-05-29" version="1">MVVTQIHSVLQRLRQEHFVASILFAAAATTILLITILLQYFKPVGKRRGKDGRRPVLPPGPEGVPLFGNLLQVNASKGDPYNRGLLSMAKYGEMTTLHLGSKTLVLLNSSRVVSEIIAKRSSQTSTRTPMPISNDIVGRNRKSLIMSQKDWAEPRRVMHSLLSGTALRQYGEFQELESTQMMAEYVFKPGMWYRHHYRYANSVIHRIALGERLVKSEEELVDMQNAVTFFVGSIGSSIIDWFPDLAKLPRFLQLWRPHWEALGQWNYDLYDRWYSPIAAKVENGTAPPSFVRDTLLHPDTKYKGDHVDGMYVAMQLIEAGSDTTREALNIMTMAALEYPAVFRAARAEVDALCGVDEQARLPTLADMDDLKYICAMAKEILRWHVIFPLTPDHTTSADMEFEGYYFPAGTGFAINGPAVANECEDPDEFKPERWLDGHEADIAHGLWAFGGGRRICVGYRLAQRSMFLNIARLVQCVDYKPNGPYNRNILNLEATGEPFPVKVDMRNKHYESLILREAQVAGVLEDAKLMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIJ9</accession>
    <name>A0AAD8XIJ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="1">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_574951</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366233.1">
        <property type="nucleotide sequence ID" value="XM_060504758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIJ9"/>
    <dbReference type="GeneID" id="85388657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06156">
        <property type="entry name" value="eu_AANH_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthamide synthase" evidence="7">
        <location>
            <begin position="175"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="366"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="846" mass="90460" checksum="E671B91648A6B88E" modified="2024-05-29" version="1">MSSEQLNVIALVSGGKDSFFSALHCQRNGHRLVALANLFPSASVSAGSDATRSAPATVIYKPTRDHVKDVQLSDQSTGKEEKPVEEEEAGKGADDEADLNSFMYQTVGHQVIPLYADATGLPLYRQPIYGGAKYEGRDYDSHAVPSSGADGDGDGDADETESMVPLLRTVMANHPEANALCAGAILSTYQRTRVESVALRLGLTPLAYLWKYPVLPPVVPGAVEDAQLLHDMAAAGLDARIIKVASAGLDDDFLWEKVSSIAGASRVKRALRRFGAAEGAVIGEGGEFETLVLDGPPGLFKKAIEVPESGRRTVREGGGTSWLSFQGASVREKRAPDAATGESCSPPRVPDALDPRFQSILESLPAARDGQVPIPDSSSSVDGFTQSDGKTPVLPRTPSDDIHWSSAAQAVSGQDSSVEQQTEDIVQQIQKLLAGHTPPLPTTAITNTIIVLQSMSDFPAINKIYSKLFQHPNPPSRVTISCGELQTGSAINVHLTIKPVLEPRERNGLHVQSRSYWAPANIGPYSQAIDVPLRGGRQDTTHADIRAVTIAGQIPLVPASMILPTEKEGNLEMQITLSLQHLWRIATEMKVQLWTSAVAYFPRTPEEADMRRQGQLAAAAWKAVHKHDEDEDGDGDGAGGPDLWDRKFNPAYMSLGEDAAAAQKLPDWSAVVTADGGGDDGEAEGPVPPFFSVEVEELPRQAGVEWHAHLGLAKVPSSSVEYRSADLAPSADVPFYRRVCHVVVSGTLVHSTIAWLAVSGPATRASKSFDEVEAWMRRAYRESVGDAGEGGDQPYLMYLNVPKCVVVAAAPAGSSGGEKGQATAYVKARSIWGVDGEKVLALGFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIR9</accession>
    <name>A0AAD8XIR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cys/Met metabolism PLP-dependent enzyme-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_693025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368261.1">
        <property type="nucleotide sequence ID" value="XM_060511333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIR9"/>
    <dbReference type="GeneID" id="85395231"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="53308" checksum="F130E67865443E49" modified="2024-05-29" version="1">MGEPIHDIPLASSAPLSLSVLPEGHDAFQPYKVEKFDEGLRYDTLQVHGGHRPDIETHARAVPIYNSVPTVAVFEKRAAALEGGTAAVATASGQAAIFNTIIGLAGAGDNVVASINLYGGTYSLFKTLLPRLGITVKWAKQETREEFAKHIDENTKLLFVESIGNPRCSIPDLQGLADVAHENHVPFVVDNTFGACGTWCRPIEFGADIILHSATKWMGGHGTTVGGVIIDCGTFDWGAAGHRFPRMIKKDGPMSFSYWKAFGNISFAMAMRIDILMEVGSILSPASAQQLLIGMETLSLRCERHTKNTMAVAQFLESHPRIAWVNYPGLEKNQYHDNAKKYLRNGYGGVLSFGPKGGDAASKMLMNFVKVVSHQTNVGDSKTLATHPWNSTHVIMSEKDRREAGITPAFIRFSVGTEDVRDIIEDLDQALARLPNDIVNAHDERLEAKLASANNGSNTAESLDSVDFIDADVSLSKANVPLGRQTAVGNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIV5</accession>
    <name>A0AAD8XIV5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CWC16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_570606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368441.1">
        <property type="nucleotide sequence ID" value="XM_060504324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIV5"/>
    <dbReference type="GeneID" id="85388223"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="371" mass="40826" checksum="71E65CEF46184EDC" modified="2024-05-29" version="1">MQGFNMGRYVPPDHEGTTTGNRLARKHPLGARASKPGILVVRFEMPFAIWCSTCPKPTIIGQGVRFNAEKKRIGSYFSTAVWQFRMKHADCGGWIEIHTDPKNTAYVVVSGAKKRDTGEEGRVPEEGEMVILTEEEREKLRSNAFASLEKTIEDRQHLAQATERIDELQDAANKAWDDPYTRNKALRATFRVGRHQREREAAVGEALKDKMSLGIELVPATEEDARRARLVEFGGVGDGVDEAGQKAFAKPLFASKDGKSTKTTTTTTTTGKAALLPKGTPKAEILASKRRETIVSEIVGNTRMARDPFLIETKGAAERSSAPRIPGLKRKRDEAGGSGVSEERRDAMKTAEPEQSLPPSKSLVAYDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJN0</accession>
    <name>A0AAD8XJN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxy-cis,cis-muconate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_664275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368603.1">
        <property type="nucleotide sequence ID" value="XM_060511078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJN0"/>
    <dbReference type="GeneID" id="85394977"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000244">
        <property type="entry name" value="Carboxy-cis,cis-muconate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="43633" checksum="205B1A9725E63340" modified="2024-05-29" version="1">MLSRSSRLLSAFQAKSSPTRLFSTTAKMPVHHLMIGTWTPPGAIFTVAFDDEKLTLELVKRTEIPEDQPISWMTFSHDKKNLYGAAMKKWASFAVKSPSEIVHEASHDMTHDPNAALSTTNTRAIFLLAAQKPPYAVYCNPFYKHASHGNIFSVSSSGALETNVQNYPYDPNTGIHGMVFDPTETYLYSADLTANKLWVHKKTAPDSPELELVGSVDAPDPGDHPRWVAIHPTGRYLYALMEAGNRLCEYVVDPATRLPVYTHRSFPLIPPGIPGATTKMYRSDVCTLSHSGKYLFATARSNSFDVTGYIAAFKLDDSGHIERQICLNPTPTSGGHSNAVSPCDWSDEWIAITDDQEGWIEIYRWQDEFLGRVARLRIPEPGFGMNAIWYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJY1</accession>
    <name>A0AAD8XJY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_749265</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368305.1">
        <property type="nucleotide sequence ID" value="XM_060513741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJY1"/>
    <dbReference type="GeneID" id="85397639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF45">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="18"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1728250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="57141" checksum="E7D50310D9EBFAAB" modified="2024-05-29" version="1">MGANYFGQTGNALSVIQIALVVCPAFILFGYNQAGLGGLLTTEDWVKTFPQIDTVNTTGETKNANSTLQGFVVATFTIGALFGSLSCSWSGNAFGRRNVIFFAGVCTLIGEILECASFHLAQLIVGRLIVGLGVGQLSSIVPVWQSETSGAKNRGRQVVLTGLFTCVGYVLESWINLGFWEFKTGPVTWRPPIAIAILFSLMLMGSIYFLPESPRWLVMKARSAEARSIIAAFRGLPEDSLEVQAEVAGIEHSLEETTQNAAKLSDMLKMGDDKLAYRFGLCILLQFYQQMSGSNLVSVYAPILFQQNLGMEAEQSKALAGGALTWKFLSSFLAFFAIDRFGRRAVFIFSGFGMAACMTCLAITTSFPKDNTAAQIAAGCFIYLFNTFVPIGFLGANFLYCTEIAPIRLRMAMSSISTANHWLWNFIVVMVTPVALNTIGYQYYIVYAVISACIPVSVYFLFPETMGRNLEEIEMLFKDSPSVFATVKFAKNRPIAMPQEFESDKPSQKADYVEKQTDDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJY5</accession>
    <name>A0AAD8XJY5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_570927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368365.1">
        <property type="nucleotide sequence ID" value="XM_060504355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJY5"/>
    <dbReference type="GeneID" id="85388254"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="908" mass="103634" checksum="E2E8D90F20D36D85" modified="2024-05-29" version="1" fragment="single">NLERFRNFKSNHLIKPIAAYEQDQDRCLLFPWAEGGNLAQYWRRTPGASLNNFELAWVFGQLTGLFEALEELHGKNCRHGDLKPENILVFIDADKNKSLQIADMGLTTFHELEAATGIRRAHEILTLTPPGTSRYEPPEMDINRNKKLPAHETRSRAYDIWSMGCVVLELLIWLACGFETVKAFRGGTAYFWEWNDDEKKYCVGSDTRDHITTLATKWQAQSAWRELLELVESRLLVVDVSKDSKSSSPECREIASAAHRQMRGIQEKYYLATRLANSIIVCEFAGFDLMDQRAVNIEPAQKQSQLNDSWESLADNDFASQVLEKIQWAQSEASLTGRKIFCSKCSIVSPPDLFPAEFRPSEAQLHCGLCSILLNALQRVYDNVLPEVVKLRQTLTAVCVDGGPNLLSIYVDPGGEIPRGMQVGLPRLPIMNSPDQFTVLNQWLQSCNTHPECNRHTAQQNLKMPTRLVKVTTPIQLVSCSTMGPKSCQYIALSHCWGQLQKHERFCLYTANHSQLQDHIDFDHLPKTFQDAIKVTRGLGIDYIWIDSLCIIQDNKDDWEKESTKMEEVFSAAYCTISAASARSSLDGFLSNRPPRPSVLVPVKGSPDLYVCAHIDDFQQDVELAEISRRGWVLQERALSRRSIYFTPTQVYWECGYGIRCETLCRLYNSKAVFLGDANFPQSALDHYRDGRQLLIQDLHERYSALAFTKASDRAVAILGLQTRLARALQTQAAHGSFEKYFARGILWKRDQVVDMTAITQSTWLVPTWSWFSKTGKIQYMNLEFDKIEWANEDFESPFSRHQDMLSGSSYYGRDEDYTILRGIARRMDVSEQQIASEVCFDRKNKFKAKDLRAVIIGRDKKSREPKVHVLVICQSQGVANDTRYERVGVASFCEKQVSKECIWVDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJY9</accession>
    <name>A0AAD8XJY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_570352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368425.1">
        <property type="nucleotide sequence ID" value="XM_060504294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJY9"/>
    <dbReference type="GeneID" id="85388193"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1186" mass="129944" checksum="68975277D78C0994" modified="2024-05-29" version="1">MNNPRDPTRLRQGLNPLLTQSLGAYHNQVNTPLSAVSSSHLHSAAHTPASAIQPYNPQEWIASPAAGSERSHQSHQFPEQGSPLPPPPYSPPRSQRPQSGFFESSPAANTSAARIPPTNVHRPSPEPSTNTSFPPPPGAGGRTSSRERRFGFHSLRRSREPQESSPPEPMPPMPMPLSRPTPLQIQIPHPMPQHNDPNSSHGPPGARRAASASAVETPTSARSRSASQSRWEPGMPLPPPPPVPPPASSRSQSVQSGPRTTTPVASPPTRRPPPTGVAALGPVPPTPADWVDQPEEPGSSSQRRHSPKLTIDTASAASSTQTGESSNSGALSSGGSLSRARAVRHDKTIVQRRAESRTRPHNSIDGTINPVQLNDIVVPNENTLSRRLTINRSGPRSGGRTSNDTPRTDEQSTTPRAPGSSSSRSRIEAATPPFSPHPSKGTPMMDGSPSVLPKALPTPPPQTRSASSSQTRFSSMTPADGPPSASISSTKHTVITQTADQFCCETIERFQAFATQESTAATDAERVRMFADFIVNESRIRRERYSSAIGAMGSEIFDLTRDLFRPMITRRESATSQAEWTPQSSEPTRSHRGSMNSVYRETPGESSSAPTSANVPGSPIVPSANNPNYSSNYMPSLSPILSLSVSDNHDDGDSRGRPASRWWEADSSGAGGKFVERSKRESKYMGVPKEAHEALQWEDSPQAGPSNPRSSGEYPPEKTGWHEMEPVVTPQPLRYSSESLGSSASPTTPNPAHLDVSRLVTLPPPYPRHHPAVNNNHPELTETRVAVRQISDLSQIETTKERFQVTSTKKREEAAKASIERRNALRSNLQQEINAGNISFADASTIEDDSVAAEKEKQKELGKTEFEQFQSQVVMPLNDLITGRIAQATTLFDKLAGGLFDDVASAADMPQEEGDDKPELLEKLTLLKWIFEAREMLHRAIFDVLTDRNNRYRDVVLTPYRLAGNEEKLQNAVAFFAEDAAKRQLAFAHEVFARTQEFQAVMERNVMRGVEVQLSAFWDIAPPLCRLLDKITPADPEALHIQIPSAEYDENPSYRRHPLQYLFSLLLHTEKSTYQFIESQTNLLCLLHEVKEAVTHAKAKVVQNEMDDGRGREFTAEERDARAQRLRDGEGRMLTDDLKEKVRVVQEQWTSALGENIKNVKQMLGEYLLETGGWDETLEEGGVGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLG3</accession>
    <name>A0AAD8XLG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Class II aldolase and Adducin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_605235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369534.1">
        <property type="nucleotide sequence ID" value="XM_060507328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLG3"/>
    <dbReference type="GeneID" id="85391227"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF41">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G01330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="2">
        <location>
            <begin position="69"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="306" mass="33391" checksum="475D157EA1D9E233" modified="2024-05-29" version="1">MAPSTSVSQIPHADVSAVKHTNGNGVLPSSTIAPEKKPGQDKSKTLETKGFPRPQKFDDPYQQRQHLKERLALGFRIFAKNGFDAGVAGHITVRDPVEPQTFWLNPFGVPWPLLKASDLIRVDENGEVVEGGPVRLLNTAAYMIHHAVHEARPEINCVAHSHSLYGQAFSALGRNLDITTQDTCAFYNDVVLYNSFGGIVLGKEEGLRIAAALGGKKAAILQNHGLITCGKSVESCVYWFLSLERCCHQQLLADAAAGGRGHETVKIDEEDAEFTYKSIGSEVAGWFSGKPTFDMMEHESGVAYKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLM2</accession>
    <name>A0AAD8XLM2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748046</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369701.1">
        <property type="nucleotide sequence ID" value="XM_060513559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLM2"/>
    <dbReference type="GeneID" id="85397457"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="68"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="386" mass="43579" checksum="FE564DB0364331BF" modified="2024-05-29" version="1">MESPTLIPNPSEQNHVTISTGATDATDSPEPSRHITNTPSLTFKGDLIILPNAQARISPTCASIADPSQHTLHLFADASFPGHDWHKGPSKPSAPAGAAVFWKPWPCTDPVDPWHSRAFQILACHNSRQAELYAVVAALETATLLAHLMPDLRRVTIFSDCQGVMNTLAAAEGSYPSALDPLVKRAFEACGSLRDKRNIRVAVCWCPGHVGIVGNEKADELSKEIRRYNFRHLVPKEQPTRVSGYEIPSKYLERARRGHWWKDEADFEWTANMPRKRFYPVAASRECDDENYDYEDYDYEADDGAYNDEDYNYDADDEFSDDEFYDDEASATLSLYSYSSATQSQTRKRERSISDPPEYPCKRQRTGRLEHGIKQSRTLEWTPTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLR5</accession>
    <name>A0AAD8XLR5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pectate lyase</fullName>
            <ecNumber evidence="10">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_16254</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the polysaccharide lyase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369807.1">
        <property type="nucleotide sequence ID" value="XM_060501406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLR5"/>
    <dbReference type="GeneID" id="85385305"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004898">
        <property type="entry name" value="Pectate_lyase_PlyH/PlyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33407:SF9">
        <property type="entry name" value="PECTATE LYASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03211">
        <property type="entry name" value="Pectate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041772705" description="Pectate lyase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="315" mass="31632" checksum="D13743D69E460B8C" modified="2024-05-29" version="1">MYIRNNLLVLALCLSTLGLASPTTSSKSGSKTSHKGSSGSSKGSKAHSSVPAHAPKGTSAPSSGSAAGGGGGGSAAGNGTTSGGANTELQTTFPTAKGSQNIAAVKTIAAGQSFDGGMVMWDRSPSTCKGQTEGGNKDAVFILEEGATISNVIIGPNNGEGIHCLGSCTINNVWFQKVCEDAITFRQTSGTSYVNGGGAQDAADKVLQHDGGGTVAVKNYFCKNCSKMYRSCGNCKTQVARHSTFDNIRLDGGKVLSGVNGNLGDGTIVRDSCVLGGAQVCENFEGNSSGAEPKLVSSGPDGKLCVATNVKTSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLS8</accession>
    <name>A0AAD8XLS8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_568124</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
        <text evidence="11">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369766.1">
        <property type="nucleotide sequence ID" value="XM_060504028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLS8"/>
    <dbReference type="GeneID" id="85387927"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000355">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="13">
        <location>
            <begin position="115"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-T C-terminal" evidence="14">
        <location>
            <begin position="348"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF19282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1729711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1035" mass="116580" checksum="D9869D4618BE7D09" modified="2024-05-29" version="1">MDLVAHELELTPLVAQIENAVEAAFNVGSDQNLKQQAFDYLNQLRADPQGWQVCTTLFTRSQRPSEVVRLFCLEVVNYAIYTQGLDRNSLSWLKDNLLEYVRNIYGQNLQDQVDPSHLQNKLSQTLTYLFVFLYNDGWESFIDDFLAIASSPNNTAGVVLYLRIIGSVHDEIADMLLTRNSNDAKRNTDLKDQLRERDVQKIAQSWKDLLAQYSGQSDVIVEMILKVIGKWISWMDISLIVNQEMLNLLLPVVGRTNRSGSEDKVRDAAIDTLTEIVGKKMRGPEKMELISFLNLRDIVAQLIASAPLSELKSTPQYDTDLAEAVAKLVNTVMADIVRALEDGQASEDTRAKSEQHLHDFLPFLLRFFSDEYDEVCSTVIPSLTDLLTLLRKVGANLPASYKEMLPPILNAIIMKMRYDETSNWGDEDEQTDEAEFQELRKRLQVLQKTVAAVDQELYIDVLSNLVSQTFTTLDQQGSQMDWRDLDLALHEMYLFGELALPNQGLGTKSQPSSTATERLTIMVTKMVESGIANFPHPAILLQYMEICVRYWQVFDARQEYIPQVLENFVRLVHHDHVRIKTRSWYLFQRFVKFLRAQVGNVAETVIQSISDLLPIKAEVSESNGDDDMSSDESDHSADALFTSQLYLFEAIGCIASTGSTPADKQAYYARLVLNPLFSDMESHLPKAKANDAQAILQIHHIILALGRLAHGFSDWQPGSTSVQNRPPPDKLVSDEFSRAAEAILIALSELNNSTDIRTACRASFSKLLGVLGSAVLPQLPQWIEGFLSQSSSKDEMAIFLRLLDQIVFGFKTEIYNVLNMLLTPLLQRIFAGLSEPVTGTDDEIQLGELRREYLSFLLVILNNELQSVFISEANQGFFESLINSVITLGRTLVAENIGPSRLAFSVLARMVVVWGGPDCAKIAENPEAPSGSPNPTIPGFDRFMIDRFHPLCWEVFQDPNFRPHNDAQSKQVLNEIAGLEQAIYLKTGEMFIQHLQSSLFPHLGIDGSDFLRSMSTSTDRKGFSSYLQGLLKSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNU5</accession>
    <name>A0AAD8XNU5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_332103</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370768.1">
        <property type="nucleotide sequence ID" value="XM_060502422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNU5"/>
    <dbReference type="GeneID" id="85386321"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="69"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1730713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="171" mass="18396" checksum="940D332963A6C2E4" modified="2024-05-29" version="1">MGFTPEVFDIANESQTAETAKKYGLTPAEVTELHQKATAAKATAYCPYSQFRVGATLLSKDGQYTSGANVENASYPVGTCAERVAFGKAITEGIRGFKAVAVATDIEAPCSPCGMCRQFIREFVDLETPILMFNKDGKYAVMRLEALLPLSFGPEYLPPPDVLEKARAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPC4</accession>
    <name>A0AAD8XPC4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_715329</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371114.1">
        <property type="nucleotide sequence ID" value="XM_060511736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPC4"/>
    <dbReference type="GeneID" id="85395634"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="671" mass="74625" checksum="F65EFA4F46492651" modified="2024-05-29" version="1">MAAAAPGLQPLTLLAGFTYYSLLGTYLDTALLLLFTSYRNKRLLADLISPYINPHLIRNQLLLLPGFLLGFIFLQICRFLLGLNAATASETETKKWKTTPVKPLLIPCTTTHRRTFPEKHAFVYSYLVVGIPVGWKGNYAGMVSCDVEEAGWLSWFSLAPRTAGRGWFHVDPADYLERGSGHLGLRGKLDAYLTSQGADPAQYPNAYLVTAARFLGYHFNPVSFWYLYSRDKELTAMVLEVNNTFDERRMYFLTTDAVPSEQRLDGRGSEPQEGIEEPASQEADAEPVPTASAAKKTQQIRMTKTWPKDFHVSPFNSRKGSYALSATDFFPPSPPSGGGAAESKDEYTLDSTITLSSSKHHPKIVARLFNSAPAIDPATMNPLQKLVFLARWWWVGFVTFPRIVKEAAVLSLRKGLHVWFRPEPLKESIGRKADATESRLEPVFRSYLRHLVAQSTAAIAVTYIPAGISTTGGAGGGLTETMLSPAAQKNPKRAEHLDVKVLTPVFYTRFVRYAHDLEAICCEFQDNGTLWISQPEVLPKLILKKPAPPLKTTNILDYVYFRAIRALRQRPDRIERPMTSATKSSGAKDGDTGGGVQKIDIRDFRNSSMDGFVLGQTDRQTRSAYRSLVLRSFLADRLALGSVELLDLQHLILRAGVAWVLSSTVAPLMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPG1</accession>
    <name>A0AAD8XPG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase M16 inactive domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_715130</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371310.1">
        <property type="nucleotide sequence ID" value="XM_060511712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPG1"/>
    <dbReference type="GeneID" id="85395610"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000003">
        <property type="entry name" value="Insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000005">
        <property type="entry name" value="nardilysin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000004">
        <property type="entry name" value="Putative insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="8">
        <location>
            <begin position="56"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="9">
        <location>
            <begin position="231"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="10">
        <location>
            <begin position="417"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="11">
        <location>
            <begin position="812"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1028" mass="117453" checksum="9E9EB5B9CD336965" modified="2024-05-29" version="1">MPNADTAAAGHPAGSAIPHREPRPQSVERVTDHLETPSLDDRTYRVVRLSNKLEALLVHDPETDKASAALDCNVGNFSDEEEMPGMAHAVEHLLFMGTKKFPIENEYSQYLSNNSGSSNAYTGATSTNYFFDVSAKPANDQEPTAENPSPFKGALDRFAQFFIEPLFLESTLDRELRAVDSENKKNLQNDQWRLHQLEKSLSNPKHPFCHFSTGNLEVLKEDPESKGVNVRAKFMEFHDKHYSANRMKLVVLGREPLDVLETWVAEFFSGVPNKDLAPNRWEAEVPFRESELGMQVFAKPVMDSRELNLFFPFLDEEKMYESQPSRYVSHLIGHEGPGSIMAYVKEKGWANGLSAGAYPVCPGSPGIFDCQIRLTEEGLKNYKEIVKVFFQYVALLQEAPPQEWIFDEQKGMADVDFKFKQKTPASRFTSKISSVMQKPLPREWLLSGYSRLRKFDSGLIEKAVACLRPDNFRMTIVSQKFPGDWNQKEKWYGTDYRHEKIPEDFMAEIKKAVSSPASERLSELHLPHKNNFIPTKLEVEKKEVKEPALSPRVVRSDGLARTWFKKDDTFWVPKANLVISCRNPNIYSTAENAVKARFFTDLVRDALEAYSYDAELAGLQYSVSLDARGLFLDLSGYNDKLAVLLEQVLITIRDLKIRDERFDIIKERLNRGYNNWELQQPFSQVSDYTTWLNSERDYVVEEYLAELPNITAEDVRQFKKQMLSQVHIESYVHGNLYKEDALKLTDMIETVLKPRVLPRPQWPVIRSLVIPPGSNYVYKKTLKDPANVNHCIEVWLYVGDKGDRMVRAKTMLLDQMAHEPAFDQLRTKEQLGYVVFSGVRSFSTTYGFRFIIQSERTPEYLESRIEAFLNLFSNTLDNMSEADFEGHKRSLIVRRLEKLKNLDQESSRHWAQIASEYYDFELPQEDAAHIKTLTKADMLEFFQTYIKPGSATRAKLSVHLRAQATAPAKEGAEAKVNGVSKDEEALPSSETPPVVIEDVRSFRASLVATSGARPAKDLTEYEDTDAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPS8</accession>
    <name>A0AAD8XPS8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_555304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371257.1">
        <property type="nucleotide sequence ID" value="XM_060503515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPS8"/>
    <dbReference type="GeneID" id="85387414"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="267" mass="29366" checksum="D794AD995CDFBBD8" modified="2024-05-29" version="1" fragment="single">MASLIAKWVSKKILAEKVENKFGREDPYFESVPATRLDGTPNGKVKKRRKALPPGLSKQDGEVLTKVKRRAYRLDQSLFSCCGVKFGWGSVIGLVPAVGDVLDAFMAMMVFRTCSKVEGGLPNSVKSQMMFNIIIDFVIGLVPFVGDIADAAFRANTKNAILLEEHLREKGKKNLKRSGAPIPAVDPSEADEWDRLQGDRTPPEYVSREPSRNGHMSAGRHERTPTAPAAAAVREERSGGRGWFGFGGRSRVDDDVEAARDPRDRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQN0</accession>
    <name>A0AAD8XQN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_564392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371785.1">
        <property type="nucleotide sequence ID" value="XM_060503637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQN0"/>
    <dbReference type="GeneID" id="85387536"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="364" mass="41187" checksum="C086D474BD52E794" modified="2024-05-29" version="1">MNGSRPSSGASGPLGFGFMGAKWPRIFFLITLVQALLCLGFECYVFWKFQTGLTDQDPHQNTDTTDATDSPRRTIPTFLTLFIFGFLYELVIVWDALRAKNTIQVIGVCIANLALLVYTAIQVEQIEEAVQQLKDNNALRDPTDDMWADVKPYLVASPCVLAFGTITMALTAWKLYQVFAWDILKTIGADYRMKKRFLHYQIYIALLKFDFFFFLGFTVQFLVIVNARTDAEFGLTIAAIPITIAILLLAAWFTRIENKVGMATVLVLYFGGLSYFIFKLVRIYQPHTAEQYMPVRKSLTAFTVITILLIICTIANCVVCMRNFGAGLKTHLRKPSRDLEKSQDLNSINLQDVKPQIASRMTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQY5</accession>
    <name>A0AAD8XQY5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_3725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371821.1">
        <property type="nucleotide sequence ID" value="XM_060502649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQY5"/>
    <dbReference type="GeneID" id="85386548"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="357"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="584"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="617"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="654"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1017" mass="112045" checksum="32573B4840252EF6" modified="2024-05-29" version="1">MVTHSNPFEASKVWEHYASRIVQGAGCTSKYIDAATRCLIRTGIFERYEKHRSKSALLPVAEACSNEWFVDRSSVRYFLLTDDTLCSLLKATTYWNGFQDSLCAVELLKVSSTLNYSMTVDQLLIRGIGVHRRCKGVSALEYICALPAADENDTWRVRQLLDHADSMCLNHTNPRSGLGLIHLSNEADVPRFRREIVEMLLERGATPDLRVNIWPYSSAMDYHLSEKHAYLAATILRHGANPTISCRSGWSAIHAATASGSVSFLNDLFEQRNPIWEIDWEGRSDSQSFKGMRPLHYAASSSVGCLQVILDKVASISLEAPSENGYTAVHFAVMSGEISAVELLHARGANINARSVDGQSALHIAVAKGNLAAVERLLELGSEMTPDCDGRTPLLLAYQQNDQNIIDCLRDHDRSQRGVVSAGMRSATLAKGIFRAIQAGNLSSCQEIFASLPTVDIDMPAIFGGLTALGVAVSFGKLNIVTWLLQQGANANYPCGNDSSIILSMILQPLLNPGLPAMLERYIATGGSVLRESRCVVAAAVRAKNEEGLVLLLDHLKANGKLYAHRVGVCSSAALALAVNRKWQGKTPLHWAASMSNVPTAQLLIDNGANIEAKDDLGLTPLLVSVMASASVQQSAVVRVLLQAGSNINCRDNDGSTPIAEACKHGDPSVISALMSRGSDVLVRDRRGRNVLHCLFFGRETVEENSVRPALFIKLNRMGVNPFELDIFGCSALHLIIHDKSMTSFVLNENMRIQDERPMPWSHLFLARNATNATCLTTAFGLYRRKLSTEKFRTFLNLEDVSIRNPLCFAASRGRIQAMENILSLGSLIDFEGCPEGSALMAASNAGNLESVIYLVRHGASISFQGHNDFRSAVELAATSPRVLRWLLVDRFTDQKKLNPSCHESTFPSTNYRPWSGIQKAEMIISGRWERQSNESSRQYWARLSSMTEQLRGKFLPPNTGKTTRRQSKLVPTESVKIAVGGYFVPYDASLGERVTRKSKWSELSSEVRECLERYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ11</accession>
    <name>A0AAD9CZ11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_569105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369123.1">
        <property type="nucleotide sequence ID" value="XM_060504152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ11"/>
    <dbReference type="GeneID" id="85388051"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF1">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="49035" checksum="4A7C2E2843ACD50B" modified="2024-05-29" version="1">MSQPATGRKRSASAMSMSDSNEYRYQSQLPSDSINPLSHTPSILRQLHLAGLAETDELPSRTQHRFPHRNWQDRDAPARPGPSASSASLSKALETSEVEEEDEEDLDEEEDDKKRHRKKKDGTPKPKYASEKSPLRPLVRAIYGFLDAGDIANAKRAFGILARSTAHGRPVDVRRNNYWALGAEILMREGGSARATATDDEAYPFANAPRVREYFRDLIQRFPYNYKHRHAVCAVDFWPALLSYEVFQVHAQHAASLRRVNREAEDWEDESWQEPSSLLDGGGGGGDSMMEGSGFRSEQVNGRDTRLRQARDQIRLKTLDMLREMAGRMNDLLEDRPFSHSAELWRVRGMVSLYIGDLLIPAYTHDEGGGQMAEARARREVERNNARSSFHKMAEHGGKLDALIQKLMAPVEEDEGPVLPVFSSLPFREYRTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ28</accession>
    <name>A0AAD9CZ28_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_606754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369153.1">
        <property type="nucleotide sequence ID" value="XM_060507392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ28"/>
    <dbReference type="GeneID" id="85391291"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="838"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="878" mass="96339" checksum="4144C2FF1A083890" modified="2024-05-29" version="1">MAQGQLASLPPLANGTSSGLSRDELHKIQQYERIVQFRDAILAGSHSKIKVPAQLASQTPTPAIASSSNPSTPAKETNGSIAQGYQVGNLQSFATTTPQASLPGLGNPPPANANLPARPFVGSGKTEINPIFLQKSDDLIKAEIQLQRQRLERALRDEVDQRRVSMKASAQSEPLADFDLSDVLSKALTLVQAAAPSSVNATLAAANISAASDSVDENSYYSSQVNSPDSSHRSSRGGNDAEITAQIQKASTTGQPFEGQAQVQANQKTQAGLQSSRPHASATHQPQGQASNSNPSQPRPVPSRPDAAPEFSRYPSVGTTQRMDRGDNTGLSTSGGGSGNTSRSEESGVMDLDDSADRSVPAAGQQQLRESMLARQPSPLIQVRAHNISPLAPQPSHVSPLAMARGQAADAQDLIIPQGTTAQVAALRNEPNIISSPDSSPQGGRSGEKRKGKKKKNGKRAARQAPDEPYIKPEPRSPSPMNAPSFIRPQKRQRRQGDEEPRYAQPERQFSRSYREEGAAPMYDTQEYRPRPASQAAAIGDYGYGREYIEEPRVISGAEYVRHVPSPGVYAVHAAPGEVYATSPASVDRYGREPARYYRDGYEVTRMSTRPMTDRARSRSPAMRERASPLMGPPKAPPGRVVVDPATGRRYYEPSTVVRQSVAPSPLRPGEPEVVYERAPIRAESRRPGPPPRDDDVLYQRTSPVYAAPRRVVTQPEYLADPQRIYRQREYSTRPMAPPGEEFIPARGGMEQRRIIEEAPREYMMRATTARPAETAVRYELPREYGRVQSVRPEQIPMQEYASAPMHLDLRREMIQPGPRSYSVRPAEPQVVRREYSARPMEQQPYYGQPAPARGEPEVSYIERPMYYTDEAPRPVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0W2</accession>
    <name>A0AAD9D0W2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_427510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370263.1">
        <property type="nucleotide sequence ID" value="XM_060503022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0W2"/>
    <dbReference type="GeneID" id="85386921"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="159" mass="17947" checksum="4BF7BCFE4B540F08" modified="2024-05-29" version="1">MRRDSGDWDSVTRQRGSADRWCFAGGLLLALVSWARSSRVRRPLGKQETSSIGTGCGRRGGIFRLTGRCQLASLPVSPFGPLGKRSQEHARLEEWTVEMRYHGMYQSSQWGTNCPSKATWRNAQRMRRKKGYKHGNGGLAAVHDQQSKRANQHCPCCRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1T8</accession>
    <name>A0AAD9D1T8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_747043</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370772.1">
        <property type="nucleotide sequence ID" value="XM_060513368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1T8"/>
    <dbReference type="GeneID" id="85397266"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="12">
        <location>
            <begin position="163"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="370"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="44814" checksum="CC7CCAC5ECE72671" modified="2024-05-29" version="1">MPADYESAARALSLSPNPPSSPSEAHADVRPPWIRNIGGNSSSSRTTTTRRMSAARFGRGGQSGSRRTTALSGANRAVRSAVKAGNRLWSMYLGLSPVQRVAVAAFLLVVNVLGLLFLIYSHAIFKWLAPVSQKWRALPFGWLIIWAFTFMTAFPPMIGYSTAISVSGFVYGFPLGYPIVATATVAGSLTAFYTSRGIFSGYVHKLVGQDHRFIALGQVLRKDGIGMLTAVRFCPLPYSLSNGFLSTIPSIKPWMFAVSTALASPKLLVHVFIGSRLALIAEKGDEMTAGGKAINYISMILGGLVGLVVGWLIYQRTMARAAELALEQAETEGGLVPGQDAPDYSDIEAGLVDPEDVAALMDDDDISLWAREADEEGGYHDDDDDENDGGGQKVGREGPVNPFDDEHNGKGGGFKDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2A6</accession>
    <name>A0AAD9D2A6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_747349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370625.1">
        <property type="nucleotide sequence ID" value="XM_060513422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2A6"/>
    <dbReference type="GeneID" id="85397320"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="154" mass="15946" checksum="2AFA2BAA0A6970EF" modified="2024-05-29" version="1">MSEIALANLEGIYRGLQSQQDLRYFPESNCREEEEEEGSHTPPNSSGTAAAVFTSGPSSSGSSGLISSPPPTGQSGDHPSGVANEVYHDSQATESAPEDDTSGVEEVEEDPVVSALGAHGIQSPGRARNAATHQHLTSVMPCAAALDLMLSPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2P5</accession>
    <name>A0AAD9D2P5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_565450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371044.1">
        <property type="nucleotide sequence ID" value="XM_060503756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2P5"/>
    <dbReference type="GeneID" id="85387655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="700"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="967" mass="107098" checksum="0D2FF6FC34463856" modified="2024-05-29" version="1">MATTPFDPPLPGSSFFDIYNDGAAQRNPVQLPGGACNYVDLTPGANGAKCGCRRFWSRFAAGKAYTDGLGSDNSFWCMCSHHACFHDDGRAASEAPAPAPVPALPPTPTTNVPRQENERPRMSREPLSPVQLPDMSSRMPAGYPPTMDFMNLDTAMAISPSKPEEPRPHRMDHVSQRPESTLQDTLSWGDFIQSQPRNGSTSLPPIPAQCLMQSQPSSTTSSSQARYLRPFYGKGLQTLSGVATSKVQSLRKDRLQDIVTSAPQDQFTKGDSSAMVVHSDHGADTPRALSPCVRKEDSVFAGPSRDTFRHLSDTVQGHEHRLERLENVSFSAAGHDECHEKHDATDLRVTDLEVRFEEVERLINDNGSVVGRLADRQTFDESTNSVVSVATSTTTARAGHSGEIFSQIQTLQSQILQLQSQLPTLTQAWEIEVVYLPFPLRRVWVELQDFKSDGPSSLDEWTQMPNTMSSHTLRAQSPFCAEWADPGHDYAWLMAKACSPTSIINSRLKSRGLVRTISVRGSDARSVQAAIHTAFGTAFTELSGGTRSASRRRSLDNKTSRFLGLQQPWVPLRKIHKDSRLRFLTPAEMVTPALWDVSFLNSVIMRSSEPRLFITQPEAYLQDLPSYESGWSWQRLREMSRFYPDSQATQEVPEADAKEDHWTWNDHLDETATAPSSLSMRQAGQRVSASPSLHHIAIQSSMRSSSPMAARGQTPVRDGRITKPPYIRTASLPPSVPANMSPSQIKRRVSSFGQRAAVPVRPNPPSISTAYKRRRTTRSPSRPLNTPRWTVSPSPMPGVIPSDERHPSARGITPHYYATPYSNAPLGETRPRGTGVVVDDSPADDDENLDPDYGSTNPYDDDDDSDYSVEMVAHVPPEREGDSSFSRQVHLPEDEPWPGIEDQEHMSDGENIDPLFSPTAEDDVHSEVSSQPSEYPSTQRGWQVPGADDGVGFRIHEDADRMQHGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D306</accession>
    <name>A0AAD9D306_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Eukaryotic initiation factor 4E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_9591</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G. eIF4E is also known to interact with other partners.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371957.1">
        <property type="nucleotide sequence ID" value="XM_060516029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D306"/>
    <dbReference type="GeneID" id="85399927"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000004">
        <property type="entry name" value="Eukaryotic translation initiation factor 4E-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="257" mass="28666" checksum="427EAA291933B731" modified="2024-05-29" version="1">MATSVQTPTNPDQQVDLSTIPISPEGGEKSETKENDSEKPVTVFHDKENFNVKHPLQNKWTLWFTKPPSGKGDNWNDLLKEVITFNSVEEFWGVYNNIAPVSELALKSDYHLFKAGVRPEWEDAQNKHGGKWSYQFKEKRSIPIDDLWLHVMLAAIGETLEAEDDGEVMGVVVNVRKAFFRIGVWTRTIGKSIPGRGDGDVAGGKGRSQDKGRDILLNIGKRFKDILNLPANEVVEFSGHTDSAHSGSSRAKAKHTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D320</accession>
    <name>A0AAD9D320_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_646204</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371285.1">
        <property type="nucleotide sequence ID" value="XM_060509935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D320"/>
    <dbReference type="GeneID" id="85393834"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF7">
        <property type="entry name" value="DUF1749-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="288" mass="31933" checksum="49B44A9847ECA4E6" modified="2024-05-29" version="1">MAPAPFSCTVHPFDSRTSHSSAYEIGPTGASNALLFIGGLADGPHTVGYTKAIAKHLETAAQDWSVFEIRMRSSFSGYGFSSLKNDVEDISALVRYLRGIGKKKIVLMGHSTGCQDCMEYTKHKEDPVDGFIMQGPASDRESIEDFVKPDWLKKSLEHAEKLISAGKEAEAIPKDLVPSFFSTPMTAYRWHSLAAKGGDDDYFSSDLEESFVSEVWNRFQQPVMVLHSAEDEFVPAKIDKQALIDLWKKTNSNVKELSGLIPGASHTVKNPESQQWLAERVAQFIQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D377</accession>
    <name>A0AAD9D377_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_598401</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371256.1">
        <property type="nucleotide sequence ID" value="XM_060506946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D377"/>
    <dbReference type="GeneID" id="85390845"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1050:FF:000003">
        <property type="entry name" value="Decapping enzyme Dcp2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="95"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="355"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="523"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="638"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="755"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="647"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="706"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="755"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="870" mass="94824" checksum="EB80464FC47AB967" modified="2024-05-29" version="1">MAEEKMQLEDWLDDLCVRFIINLPEEDLSSVARICFQIEEAQWFYEDFVRPLDPTLPSMTLRSFSLRIFQHCPLLAPFSVENHTKAFEEFLQYKTRVPVRGAIMLNEAMDSTILVKGWKKGANWSFPRGKINKDEDDLECAVREVYEETGYDLHAAGLVPKNREDVKYIEVTMREQQLRLYVFRDVPMDTHFEPRTRKEISKIQWYKLSELPAFRKKGNQPQNEAAAAANANKFYMVAPFLVPLKKWVVQQKRKDAVKAANEAHFNPYSLHEEPVTEDEVWQTEPATDVSTRTPGLDTLEGATQELQRLLKVHPTAAQATSKPASPDIGADKGASLLAILQAKNQAVAQGVPVSQLPHTPLDHTIRQAPQPQSPHGQHHPQQRAPLASYQAPPAFPIGPDGTPQAWAFQQPGNAGSTHPQARQYGSSMMGGAAHLPQPPLRHPQPLPPQAQKILLNRNAFADGTPPPPPQHAQGTVNQPLNAQYQSAHFQQQGQNMMYQPKPPSSQLSNHSMALLGVLKSDTRTASPDKARQANQQLYGSASQGQGQSPIGLHGNGAPQYPQSPSMPGAGVVHPQGSPSMRTQQPVDPAHRSALLSMFKNPEVSSPPANQPVELPGTTASAALLKGISTVKASNQEVPSPVFRGVQPASSSPLSRPPQSASDPTSQIPFQSLSLQSQLSRQEHRSPQNVGGYSPRTTENKGLYHQGANNNPAIYNNHSPQMHPNQILQRAENMSKPVGPRAPALASVFGVDKPASLASPPSASALPAPAGLQQKSQMPPEQRQKLLSLFGKPQSPSPGPGFASEDKGKAREMMAPPDGSMRSRVASLASASGQGVPEGLSESRRGSQTPISPADRSFLLGYLASVANNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3I9</accession>
    <name>A0AAD9D3I9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371810.1">
        <property type="nucleotide sequence ID" value="XM_060513223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3I9"/>
    <dbReference type="GeneID" id="85397121"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="33743" checksum="0304DAEB86BB6632" modified="2024-05-29" version="1">MSQNGGTVGTEYPDYTEHGRQYGSFGRGRYLFPVDELEKDRLDIFHHLITKARGGLWEVPLPAKPHVLDLGTGTGIWAIDVGDKLYVNEDQRAQVLGLDLSLIQPKLIPTCVRFERADVEAPLPAPEQTFDLVHIQMLLGSIRDWPDLYRKSFRHIKPGGYIEQVEIEWIPRSDDNTLTPDSPLVFWGENLRHAMHRYGQSIDIIDTKKELHAAGFTDITEKMIRLPTNPWSQNPMEEELGRWFNLGLTHCLEGLTLAPFIQVERWPKHDVDRLVDDLKKEICRLNVHAYCRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3N3</accession>
    <name>A0AAD9D3N3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-glucuronidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_564232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371736.1">
        <property type="nucleotide sequence ID" value="XM_060503617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3N3"/>
    <dbReference type="GeneID" id="85387516"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031728">
        <property type="entry name" value="GlcAase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16862">
        <property type="entry name" value="Glyco_hydro_79C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-glucuronidase C-terminal" evidence="1">
        <location>
            <begin position="441"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="572" mass="61769" checksum="FC214F11ADC5214F" modified="2024-05-29" version="1">MSSVIRSVGSALGDELECLFSAFSPWFYAFKLPSALTGVVELLAVGAVNVTVPGPKEASPVFDAFVSYSLEFAFFPDFAGNASAPNKFSDNLLANLGNLQGVRPYIRVGGNTQDYALYDVSLPYAVNGSYDFARSKDYPTTIHIGPSFFESYSTFKDTKFTHGFNLGLGGNRSEGWDTLKATVPLACKAIGRDNLDVWEYGNEPDLFSTSAQGPARPSSWNETTYVEQWLNGTREIASVLAEACPDFPKPVFMAPSNAGTANRLRAPAQWAAGLNTDDNVALFSTHNYISGAESPGVTLRGTLMNHTRTVQSVQAHIKEYANLTGRFDDVPPHIYGEHNSLYNQGKPGLSNSFGAALWGVDLNLYAASQGIKRVHMHMGTDYRYQSWQPVHTNITALGTKAPYYGNIAIAAFLAPSKASPVTLVSVAYIPLPASDQETTSAYAAYHGDTLARILVINLNPHNSTVNGTGTTPDPDSNPFRGVKVYSFAVPWANDVFANVRRLAANGSDAISGVTWDGWSYNYELDEGKPVRLGNVTVGETAIVYGGRVTVAVRDSEAVVVSPVLGCRAKRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4T9</accession>
    <name>A0AAD8U4T9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_658307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000270">
        <property type="protein sequence ID" value="KAK1704084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357377.1">
        <property type="nucleotide sequence ID" value="XM_060511030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4T9"/>
    <dbReference type="GeneID" id="85394929"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="2">
        <location>
            <begin position="140"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1704084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="368" mass="41016" checksum="72F47E021A0BC39A" modified="2024-05-29" version="1">MASLTNSLTTPLYILESGYLMTVPLAQDGGMTTWVLVDKNRLPNQRDILCSCETFRKRCLVSDNSMGNTTEGIVHGIVSVFCPGNFRGRGYAARHMKELATVLRDWQPEDGMVVGSVLYSDVGKEYYTRLGWTPNPVSGHLVLPPARMEIPAGSRPIFESELESLCLRDQAVMRNDMATPSASRKRVVILPDLDHMLWHVHKEDFATKQIFGKKAVINGAIAGAAGKQVWATWVLRYYRHPNHHSTEDADDKSVLYILRLVVEGDETANKPREGNITMPMEDYAEQAAALKAVLQAAQAEAADWRLDQVQLWDPSPMVKCLLDRSGLDAVYIERQSHSIASLLSFEDGEGLGSEDAPILINNEHYAWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U621</accession>
    <name>A0AAD8U621_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetylornithine transaminase</fullName>
            <ecNumber evidence="5">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_593252</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000209">
        <property type="protein sequence ID" value="KAK1707510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358047.1">
        <property type="nucleotide sequence ID" value="XM_060506610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U621"/>
    <dbReference type="GeneID" id="85390509"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002325">
        <property type="entry name" value="PRK01278.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF79">
        <property type="entry name" value="ACETYLORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1707510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="468" mass="50253" checksum="C29D7B71960089F5" modified="2024-05-29" version="1">MAFRAPLRLQLAKCQPRLAVASRINSRALSSAAAAATSDVKSNFGQKQSSVPNPDPTEDSPSAALVREHAPYMVATYARPPPVFVQGQGSLLWDVEGRKYLDFTAGIAVNALGHCDPELTQILTEQGSTLMHASNLYYNPWTGALSKLLIEKTREAGAMHDANSVFVCNSGSEANEAAIKFARKAAKVSQPSGDKYEVVSFNNAFHGRTMGSLSATHNPKYQEPFAPMLPGFKLGAFNDVSAINETVTEKTCGVIVEPIQGEGGVTPATDEFLIALAKRCREVGAVLIYDEIQCGLSRTGTFWAHTHLPKEAHPDIITTAKALGNGFPIGATIVNSTVSEKIKVGDHGTTFGGNPLACRLAHNIVSRLADPGLQKAVAAKAEIFKTRFDALRERFPDLIKEVRGRGLILGLQLTQDPTPIVKAARECGLLIITAGTNTLRFVPPLTITEEEIQQGLDIVEEAISITRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7J4</accession>
    <name>A0AAD8U7J4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_640148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000166">
        <property type="protein sequence ID" value="KAK1710876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358936.1">
        <property type="nucleotide sequence ID" value="XM_060509474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7J4"/>
    <dbReference type="GeneID" id="85393373"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF5">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="4">
        <location>
            <begin position="140"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1710876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="42158" checksum="71BB40BE0C8D8B4F" modified="2024-05-29" version="1">MSTIKVGVVGYGFAAKSFHLPFITANNDYQVIAILQRAEAPEDLSSAAPGSHCKVDFPNIRHYRTEEEFFADPDTQLIVVATHTDTHASFAEKALRAGKHAIADKPFARSSEEADRVIELAESKGLILSCFQNRRWDGDFQTLRKLIKEDALGDIKEAEIHYDFESPPWLSGMTKKEYTPGDGMAFGLGTHSIDQAVTLFGQPKSVTGFFRAQRGIESEVEDSFTIILQYDGSQKDLLVTVKTSVTTPMSQQLKHFIRGTKGSWLKFQQRSTCPQEEQIAEGRKPLEPGFGEEPAEVYGTLTTYKEFNKDQKFDEATNKFVGRVPTIAGRWLGIYENLADAINGKAELEVKAKQSRDAIRIIELARESHKSGATVAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7S8</accession>
    <name>A0AAD8U7S8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_758322</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000219">
        <property type="protein sequence ID" value="KAK1706947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357947.1">
        <property type="nucleotide sequence ID" value="XM_060515018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7S8"/>
    <dbReference type="GeneID" id="85398916"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF43">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16230)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="11"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="495"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1706947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="57505" checksum="7E9541B24B39A910" modified="2024-05-29" version="1">MVQFNTYYLLTIIVISCGSIPKGYDEGGFSASTGLASFKQDFGLVSSLWKGNESGLADRKANISSFGVLGAAFGSIIALAVNDRLGRLRAWQLFIAVWMTGCLMQVFSSGILGLMLFARIWGGLGAGGLTVVAPLYLSEIAPARSRGMVVSIYMVVLLSFLTIGFFINYAANATLAATRMQYRLVIAIPLIPVGIAFVTSFFLDDTPRWLASRDRGDEALAVLAKLRHADPSDQALAHEYDEIHEQIHTRQQILADSSTWAIIKDIATIPTYRTRFLLGAVMQTVAQWSGGNGITYYIPEIFRYAGVVGENTSLITSGAYGAVKLVFTMVFTWGLVDVFGRRRCFITGLFLQCITHVYMAIYMAIWIDGTNKPASDAAIASVFVYAVGWSIGLCTVQYLYGTEIYPTRIRSVCYASNMALHWFFQFAVVRVTPNMFVSLNVWGAYVFWAVVCGVGLVVLGLWAPETKGIPMERMEELFSGRWWMGWRASVDLDSSETKPFGRGDSSGKESKAPFAHDRKTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8G4</accession>
    <name>A0AAD8U8G4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_95915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359412.1">
        <property type="nucleotide sequence ID" value="XM_060516030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8G4"/>
    <dbReference type="GeneID" id="85399928"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="64" mass="6836" checksum="EC175BEA235053E3" modified="2024-05-29" version="1">MAVGRSMSDLGRLLQHRIGYHSAAHGPADAAGFRILDTAGSARELLTANGLGRIAHSQTIHHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8I3</accession>
    <name>A0AAD8U8I3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_593414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000216">
        <property type="protein sequence ID" value="KAK1707140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357988.1">
        <property type="nucleotide sequence ID" value="XM_060506624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8I3"/>
    <dbReference type="GeneID" id="85390523"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1707140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="63" mass="7434" checksum="EAD9FC774F7BD337" modified="2024-05-29" version="1" fragment="single">VINTTNISSLYNYTFGFILTERYKGYDFFIKFIKLIRAEINTKYSKVVIIDFKKVIKSVIITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Y6</accession>
    <name>A0AAD8U8Y6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_591989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000182">
        <property type="protein sequence ID" value="KAK1709428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358562.1">
        <property type="nucleotide sequence ID" value="XM_060506495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Y6"/>
    <dbReference type="GeneID" id="85390394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01094">
        <property type="entry name" value="Alkanesulfonate_monoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050172">
        <property type="entry name" value="SsuD_RutA_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42847:SF4">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="6">
        <location>
            <begin position="48"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1709428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="394" mass="43342" checksum="F743D4400384300F" modified="2024-05-29" version="1">MSPTSVREGGPELKGPLDFKDSPLRRASRQPLLLGLFLNLQDINFSTQPTTNTWTFDYNVALVRRAEQLGFELAFSRTQWLPKGGYDGEASLDAFVALGAMAAVTESILLISTMHVLYGPLHPLHIAKYGATLDHIAKGRWGINVVTGHRAVEHEMFGRQRIEHDQRYKMAGELFDVVNSLWNETENISYEGKVSPWRLENAWVTPKPQFGRPILVNATGSPAGIEFAARYSDLIFITSPGTAHIDSALETLPAHIANIRAAIEAQGRSGVKIIINPIIVSKDTPEEAWAYAESIAEGTKIQAGTKKFGTANGAYDSDAHAWRGRKDAKENKGLNLGGNIEIIGSPEQVVEQLDALHKVGIDGVQINFYDFAPDLEYFGEKILPLLKEAGLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Z1</accession>
    <name>A0AAD8U8Z1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_735760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000198">
        <property type="protein sequence ID" value="KAK1708226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358258.1">
        <property type="nucleotide sequence ID" value="XM_060512974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Z1"/>
    <dbReference type="GeneID" id="85396872"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042156537" evidence="2">
        <location>
            <begin position="19"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="419" mass="42121" checksum="CA67EC3A17EC9947" modified="2024-05-29" version="1">MQKFTLLTFLVAALSVQARHHDGAAAAHELLDRAEHYKHTAHRHNGLIPRQTGPLDPTVTPPPSFNSTGPSTFSTHLFTNTTTTHRNTTSSRSSSTSSSSKSSSKRSSSSSKSSSRSSTSSSSNTASSSSSSSSRVSSSSSSQASSSQSSFTLSSSISSSFSSSAPTSSTLTSGTSLSSTAVSTSSGTTSAVTSSDSISSTGSRPIESSARSTWSRRESTHTSVSSETFSLTVSSGVSWSTSYTTATYTTVDANGNPYVPVAPIAIPVVGGVPVVPPVGGGGGGGGGAGAESTTTTMSSSPPTPTSLRPASTFSSSVDPITSAVESSSGSSIVEVVTATSPETTIEVSETATSAAPASTSAAPSPVPCYNYEWKSYGWCCPGPDSPCQNDLGTCYFDGSGATDVLPNTAACPPGEGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9D4</accession>
    <name>A0AAD8U9D4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_592137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358483.1">
        <property type="nucleotide sequence ID" value="XM_060506505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9D4"/>
    <dbReference type="GeneID" id="85390404"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="317" mass="36730" checksum="CD13F1D8D38431B1" modified="2024-05-29" version="1">MGKKKVLVCYGVDIDAVAGWLGSYGGEDSTSDISRGLWAGTIGTRRLLKLFEKYNIKASWFIPGHSLETFPEECAMVRDAGHEIGLHGYSHENPVDMTLEQQRDVLDKTWKMLTEFCGKPPKGSVAPWWETSEEGTELMLSYGIEYDHSMSHHDCQAYWLRTGDSWTKIDYTKKAEEWMKPLVKGKETGLVEIPGSWYIDDLPPMMFMKNSANSHGWVNPRDVEDIWRDHFDYFYREYDEFIFPMTIHPDVSGRPHVLLMHERIIEHINKHEGVEWVTMGEMSDYFKSKNPAPEGGLMPATQEEVMKKYEEWKKTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA96</accession>
    <name>A0AAD8UA96_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000165">
        <property type="protein sequence ID" value="KAK1710903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358963.1">
        <property type="nucleotide sequence ID" value="XM_060510920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA96"/>
    <dbReference type="GeneID" id="85394819"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="25450" checksum="618332DC465F867A" modified="2024-05-29" version="1">MQSQGNSAADLPVAPSMHRSGCAAERHGLPDVQRTGYLIQHYIAELESYVKVQQMVSGETSLIIKALAAVITNLHHIKRKAAITPKDIEHVIAAVKDAMSAANARTKTAGVKEAEAKAKIRAETEDEERRCKNASTNIPVAAAFLHIVDTLDIAYHELGKALQASQFQSYRTLERENTRLQLNLEAQEDTIARLEQEIAELKVSFLAQPVKFRAILTRHSNPKAVRLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAI6</accession>
    <name>A0AAD8UAI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquinol-cytochrome C chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_638487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359417.1">
        <property type="nucleotide sequence ID" value="XM_060509368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAI6"/>
    <dbReference type="GeneID" id="85393267"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="2">
        <location>
            <begin position="148"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="326" mass="35767" checksum="83E3FC34D714BA7D" modified="2024-05-29" version="1">MACQSCRYQARLLARSLRATADLASASSAQQTSIAATARRAALTTSKTGGPAATTTMGRRHFSQTATRRDAAPSSGGLKQAIASGMMAAAPKTMAATLTTSRLEALYKICSSPALYKISEQERAKDMVRMTAEGEEVGDPIGPWLQFLDLQPGFSSWSQATMLHMYLVLARLRCLDRDSSRNLQHQFIDQFFFDCERMMHLNHGMTSSALRQRYLKEIFVQWRGLIAAYDEGVVKDDKVLGAAVWRNLFKSREDADLRQVAAVVGWMRATLQDLEAAPVEDILVAPAKVFKRDVREMFALVDAVGPQVKEDVAKLGGGQEQAAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAT6</accession>
    <name>A0AAD8UAT6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_638985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1 2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000152">
        <property type="protein sequence ID" value="KAK1711969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359293.1">
        <property type="nucleotide sequence ID" value="XM_060509396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAT6"/>
    <dbReference type="GeneID" id="85393295"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041778282" description="Metalloendopeptidase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="3">
        <location>
            <begin position="36"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1711969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="402" mass="44790" checksum="DD56CFEEEE0A961F" modified="2024-05-29" version="1">MAPVSCKSLAALALALSQPALAAVFPTNIFNRSEIEAMSLEKRGSMYAYQLWDSAEIPYILQGLPHDLSESIRGAMREWEQSTCIRFLPKTSQGAWANFKKFDDGCYSKGLGSPGSGERHVNLDYPNAWEKFLSAGTYKACLDAGTPSHELGHLIGLTHEHQRPDRDQYIRVLTDRVQKDELDQFTIDTSADVSVPFDYNSVMLYDTKAFAKTNKLTPISGSASLKHTMETITDKKIDPWNSPTANDFKAVNDAYACEEYYTRVIPQCLAGSIPSNGDFSSYSFILDKHTEAYMAANGYTHVAAHQNCRANMVGQDTDNWGFTPLNGWGPRAQYKITTNRCKKDHDRHASRYEVALCKGDNEGACDIKCGLRRVCPFDASGKQVDSKAIDVVDNNLWICHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB06</accession>
    <name>A0AAD8UB06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_146021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358499.1">
        <property type="nucleotide sequence ID" value="XM_060501307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB06"/>
    <dbReference type="GeneID" id="85385206"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="333" mass="36441" checksum="4E4596A51A0BE11C" modified="2024-05-29" version="1">MEILETPLPQNQLKTHDVSDDAPGAPLINSTPAVSSPSCLHDNDVFDLLWLAFDNKQAVQGVFNVQGAVASGKAELVVFAWQNLMMKDHLRDAIEHRTWQFCKEHHIPTFFVSSMYFLGHGCGFDYAIRAVAVTFQEGSELTDEINDMKRRIQMLRRIPDESEAEEFINSDTLEGKPDGFEAEDHICTGTFGNKPDDFKPEEDVCVENLNGKPDDADTQDSACSEILSHKPDGLETEISASADVLESKPSDLEAIQPMRADSFGSLSMASEIAQSTRTDSFGSTSSASSMSGESDDFDPLESSRADSFGSQPSMSEGSVAEDPTFAESMEDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB77</accession>
    <name>A0AAD8UB77_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_79140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359807.1">
        <property type="nucleotide sequence ID" value="XM_060515732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB77"/>
    <dbReference type="GeneID" id="85399630"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041993259" evidence="1">
        <location>
            <begin position="21"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="112" mass="12756" checksum="497FB19FD0A21D15" modified="2024-05-29" version="1">MLHALLLAQLFLNLVYRFTALQFAASFTQFPQPSTRPIHLSQADAMSTNKIWGQLQVDLTKAHPIQRITDSGDFRFVIANDFPPPQPVPWGKDQTWSPVLSKSLYYKRPAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBC1</accession>
    <name>A0AAD8UBC1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="1">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_755699</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000106">
        <property type="protein sequence ID" value="KAK1717515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361002.1">
        <property type="nucleotide sequence ID" value="XM_060514652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBC1"/>
    <dbReference type="GeneID" id="85398550"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008142">
        <property type="entry name" value="AlaDH/PNT_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00836">
        <property type="entry name" value="ALADH_PNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="6">
        <location>
            <begin position="114"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1717515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="18300" checksum="8CEC9ADFE8AD2D97" modified="2024-05-29" version="1" fragment="single">MANLSVLRPTLAYNVCSSRASSGRLVGSRAWRNGLAAVAPASVVVAGKWQSTHARARRQTKALVPAVSYRPLQLIRHASVVSAGSSAGPTATPAATYATVAEPQSVPYAQLTVGVPKEIYLNERRVALTPQNVALLLKKGFAKVLVERGAGASADFPDEAYDRAGATLVDHPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBI8</accession>
    <name>A0AAD8UBI8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_641789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358444.1">
        <property type="nucleotide sequence ID" value="XM_060509573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBI8"/>
    <dbReference type="GeneID" id="85393472"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF10">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="40483" checksum="030CF16430EAC8EE" modified="2024-05-29" version="1">MAKSASPTANTSAELSSDPAASPAHGGITIEAASLEVDDNSSTIDDSSTIEDRLSSYTASLSSSVIDYPEEYGRRYHAFRAGSYNFPNDEREMDRLDLSHLVVVKTIGNRFFLAPVDTETTHRILDVGTGTGIWAIEVADLFPTAEIIGNDLSPIQPEWVPPNVKFEVDDVECAWIVNKKYDFIFSRGMAASIGDWPRLVRRIYENLAPNGWAEFEDMSVIYGCDDGTVTEDLALMKWARLFAEACQKLGREDSPGPKLEDWVRQAPFKNVVHQHFKIPLGPWPKDAHNKDVGMCNLAQTLEGLDAFTLKLFIGVLGWTREEVVVLLAQVRKDLKNSAIHAYLNYHVVYGQKIEVEEERAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBP5</accession>
    <name>A0AAD8UBP5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_640496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358845.1">
        <property type="nucleotide sequence ID" value="XM_060509491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBP5"/>
    <dbReference type="GeneID" id="85393390"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052073">
        <property type="entry name" value="Amide_Lactam_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171:SF4">
        <property type="entry name" value="ACETAMIDASE REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47171">
        <property type="entry name" value="FARA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1710566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="734" mass="80994" checksum="0098E7FB38A3DBAA" modified="2024-05-29" version="1">MSAAGRRGASSPTGSASGQASKKARTNGRACVTCHQRKVRCDILEKGTPCSKCEANNISDCRIFEKKKTKCSTRVSRSPNISIQPRTTTAPSSRPTTTPTASNAASPWVPVNVDSRPGSAPGNELNAQTHYATEVATRNLADFLDREETGYQDILPSGRLYFIGTEFSNLNYLVRQRSQRPDQHVLHFGSHPLAPRMSSVPPEALELPTKALADELVQAYFVHINRGIPIVDEEFFMKKYNNTDTNEDFARQRPLSLLLLNAILLVGAHVLSNQRDELKALKAVFFKRAKALFDCRFEQHRETYLQAAILLTWQCDDLEDVISNSWYWIGIAARTAYGMGMHRDASPSGLNVMDKRLWRRLWWTLYQYDVLVSMAHGRPQAISLDDSDVPLIEQCHLEDTPEAEASFIVQHTQLCIIFAKVMKKRVALRCKEGEKAEATRKADIALAELVTNLPERLQLSSGDPDIWQSMFHITYNSFLILLHRPPPRAVPGPSSVEASNDLTICSDAAATIASIFESLRKREMLAGLWLPSLHMLFTALVHTASQMHSSNPIVAAKSKRHTESMIHTLHAMKSQWLYAQSLLNLFEPKRQRNRGLDQQSTHLGEVSNRVGSGGEQNPSRISLPTDILRFNDHAIAGSSVLASVGDDHPGQSLVSGATYGSQNTSTAPSHGLARDPVEQYAAAVVGNMSQGGQPYGTGFVGDDMGLTDADTMDMLQLPSALEFLLAGAGNNFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCF7</accession>
    <name>A0AAD8UCF7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">E2 ubiquitin-conjugating enzyme 11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_587662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360467.1">
        <property type="nucleotide sequence ID" value="XM_060506065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCF7"/>
    <dbReference type="GeneID" id="85389964"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000068">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-20 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="32"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00080142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="180" mass="19730" checksum="898CE0CB3CD9D006" modified="2024-05-29" version="1">MDYSMEDTQNSAPGSVPAAKIAGARKGPDAQSVTKRLQTELMQLMTSPAPGVSAFPSADGNLMSWTATIEGPEQTPYAGLTLKLSLSFPNNYPYAAPTVLFTTPIYHPNFDFSGRICLDILKDKWTPAYNIQTVLLSLQSLLGEPNNASPLNGEAAELWDKDPEEFKRKVLARHRDVEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD10</accession>
    <name>A0AAD8UD10_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_654469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361917.1">
        <property type="nucleotide sequence ID" value="XM_060510720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD10"/>
    <dbReference type="GeneID" id="85394619"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="596" mass="63871" checksum="F2026D876248CDDE" modified="2024-05-29" version="1">MTKILLPDCSLPRPTDTETVPLLATADSAPDGPIVDLKYAKYQGTFNSTLNLNIFRGIRYAAPPTGDLRWKLPQDPTSNDTLTPATANPPRCPWARRSLQYPKTAAEEAALQNFAFAGDEDCLFLNVFAPAGVAALPKPLPVVVWIHGGGYNLDSASSFDFSSQIVTNNNSYVAVVIQYRLGAFGFLSSEELVKGGGVTNAGLWDMIHALKWVKTHVDKFGGDPRRVTVAGQSAGAGGALLLAASDEAVGLFDGVIASSPYLTTLPSELTFDNSKHDGDRPTRAYKSLAERIGCSSNATSSSLLSCLQNADSLTLQNASDWVSTQGRYGQWEWRPVIDGKLVRDTLTQELSQGKADVNGRRVLTSNVADEGPYFTWQNITSQAHFVSFLQSNYPALSEGNVTEILATYAQKHEAFLMANSKDANNTDPGFSTNGLESPYATTVSDYATGWQQVANNFYAEATFICASHWLANAYAAKDGARAWRYQYSVPPAYHGVDIGSGSAVDVLLAPVDTPGTAVTMPLRLALQNSWGQFITRGEDLVLGGSGGNSTVWAQWKEGGRGAASMLNANMTGGVPVGKVSSFDGMAQKFAHCVNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD48</accession>
    <name>A0AAD8UD48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_756911</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359594.1">
        <property type="nucleotide sequence ID" value="XM_060514819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD48"/>
    <dbReference type="GeneID" id="85398717"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF6">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041931353" description="Mid2 domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1712978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="34268" checksum="49B3F44C00A7FEBD" modified="2024-05-29" version="1">MRATTFVLAAVIRFAYAQDIDDIPEYVWPPFAAYCVANGWLNTFQTDVISTATLTETQPSIITITKSATYDVGDKYTTVDIETSTSRIESGLTASQATTPTAQSTASIPESTPTAEPTSTIDGGNSESSSDRLSTGVKAGIGAGAALVAMLAVVLLFWWRKRKKASQGDGNEDITPELSGGDKSNRYELDSYTAPLEADKKSPAIFSNQQNQMMAELDGTPCASPEPNIHERHEVTPSVEQHTVSPEVVSTISPPKSTLSSAPKPLIADMAELEHLLHEERLLRDRRQTLEQLQRIQADELALGERIRTLRQSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEX3</accession>
    <name>A0AAD8UEX3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Autophagy protein Apg6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_635512</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360318.1">
        <property type="nucleotide sequence ID" value="XM_060509184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEX3"/>
    <dbReference type="GeneID" id="85393083"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000005">
        <property type="entry name" value="Autophagy protein Apg6, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="154"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="285"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="205"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1715519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="494" mass="55004" checksum="317AA7A50FB50DD4" modified="2024-05-29" version="1">MICQKCRTPLKLDSSLEELNPAAYDLLVASSSQQSPKKTPSSRPYHPQDGQRKVLYDKVSQNAASATFKRHGSGPSNSAQRDSTMSFIYLTESQVAQPVLSRPEPLPPNTKLNRGNKGGQKSLEEQRGGSKAHEIERINKLFEILSARSDIDHPICVECTDMLVEGLQKKLEAAARERDAYVGFLKQVQSDQPNEEDVKAQEEALKKARQAETGAMAELLRLEQEKASVDAEIIALEKESQQLDHEEEQFWRERNAFATKLADFQNERDSTNSRFDNDAQLLEKLQRSNVYNDTFCISHDGTFATINGLRLGRLSNKPVDWPEINAAWGHALLLLVTVADKLGYKFDGFEPQPMGSTSKIIRFELPSPTASRLGSHRNAPPPAPKKHVLELFSNGDLPLGLTFMHRKFDNAMVAFLELVRQLGAFVHRQTAADGHPLSLPYKIEGDKIMDVSIKLGIAQDDGWTKACKLTLTCCKFLLAHASNVNTSARAANNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFK7</accession>
    <name>A0AAD8UFK7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diacylglycerol kinase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_722592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360885.1">
        <property type="nucleotide sequence ID" value="XM_060512483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFK7"/>
    <dbReference type="GeneID" id="85396381"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055916">
        <property type="entry name" value="DUF7493"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24321">
        <property type="entry name" value="DUF7493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="143"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="532" mass="57729" checksum="EEB7D8EEDB1C7E93" modified="2024-05-29" version="1">MATLAGEHNTAPNGTESISESSQSYGKPASRNGPPETIKVDDNKSLTLTSENLLLNDPTANKANRTCGFAGFGASAPSTQTVPLYNVLWAEQTGETLTIDYAKQAGKQRVQAAIWTFTLNDAEGPDVKSWIDTLMRKAYGPAKLCKRAKVLVNPHAGPGGAEKKWRVDVEPLFKAARMPMDVEHTTYSGQALEIAREVDVDAFDTIVTCSGDGLAHEVFNGLGQRPDASQALHKVAVSHIPCGSGNAMSCNLYGSYRPSICALAIVKGVETPMDLVSITQGDRRTLSFLSQALGVVAESDLATEHLRWMGGARFTWGFLVRIFEKKCYPCDLAVKVEIEDKAGVKKHYKEYTRSASVTHTGASEPPRAENADAVSSPFGDQEGLPPLRFGTINDDLPDGWELIPHDKMGNFYCGNMAYMAADANFFAAALANDGLMDLVCIDGDMSVGAQLSMLMSVENGKFFDNCLVSYRKISAYRIIPKNQKDGYISIDGEKVPFEPFQAEIHHGLGRVISKRGKYEAPGPIGWEKMSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGR6</accession>
    <name>A0AAD8UGR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_782780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362908.1">
        <property type="nucleotide sequence ID" value="XM_060515568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGR6"/>
    <dbReference type="GeneID" id="85399466"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="34147" checksum="7EC530004FFC48E1" modified="2024-05-29" version="1">MPKRLPEVSVPSTITDDKQQPADSVTHDSLRGNSPLDSSKSTAALDHGTTTDTALSLDYHLDDFSWDMSLDPQLDGSISAQMAEEEMGRITSTPQIADPAIQNEAFVKISKINVELHSYLSSVEIDRPHLDFCSSAHPPSILSVDGHTMPELVPVAFQDFIGVLSGLNKTAVPITNDINQPLVLIITSCYVQIITIFEEVSVQIRKRLEAIAWNPIQPTEGIKFGAFPIEDAHLQDVIISQIVESLREKADRCRGVQQSMVSPPGTVMSFEILSSQSDLLHGQLESKDQASVPRSIGLKSANQHLRSTLTAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGS9</accession>
    <name>A0AAD8UGS9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_743407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361338.1">
        <property type="nucleotide sequence ID" value="XM_060513140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGS9"/>
    <dbReference type="GeneID" id="85397038"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="192"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1718838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="42096" checksum="C97C296DD36657CF" modified="2024-05-29" version="1">MSSTLTATTSSQSQTLRIESKDPMKSTWRRSDKRSWKIGHWIIERLGLYHDELDRTAPVHSKAESVPYVPHWQFHRWILLHATIPLLFHQSFVSLTGYNVHPVAAFVFYSVAIKAVAIHQINIMRGLGQRYGFLDGDKHERDGVPDKSVKTVLESLISTATFRSMMAVILSYRSNEAPTTINWMLLPFEIGLYGVVLDFWFYWYHRLMHEVDSLWKYHKTHHLTKHPNPLLTLFADSEQEFWDIAGIPFLTWATLKLIGLPMGFYEWWFCQEYVIFTELTGHSGLRLYATTPTPFAWPLQFFNCELVLEDHDLHHRKGWKTSGNYGKHTRLWDRIFGTCMDRIECTADSADYTNTAVIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGW6</accession>
    <name>A0AAD8UGW6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_753951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362998.1">
        <property type="nucleotide sequence ID" value="XM_060514419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85398317"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1439"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1876" mass="204648" checksum="2771313AD0FC93CD" modified="2024-05-29" version="1">MPTPPTEDDRQRRIIQFAEEWGLEPPPSPTPLTRPSSPPSFRTPEDDFKAEELLKRKQMSHGRTESTTNLRRAFTGKKKSWDYKVVFDTLDKHVADRGSPGVAEALITQLVSSGGDVNMAQKAKTSILPRRKSLDSFGERSKLLQHAVHNGQVDMIQVLLPHADTFALDASLPVAMQSENVEVVELLLRYGAGVAHSPEAQESFRQACAAGGQADLVGIVLRSEGRPPTSWLSQCMVDATKAGCLETVLQLSRSNADGDYNQAEALKVAISQGRHDIALAILMGNHPPKRPGLDEAFSNLLDHPSMNPRDKLAVAELLLCAGTDGDAPAMALIHAAAAEFQDMVSLLVKYGVSIEYQDAMAIRKAVQNGRVDVAHIILSGNAELSATHASECVELIPKNMGVESRRLLLDLLLRRGANGTALHDMLIEAAEAGDVDSAKLLLTAVFPGGRPIAEHDVKKGPRSMVYDRHQTASVDHKGGLALQIAVMRSDAAMAKELLMSKPSSDTLAQIFPLTKTLSRKNRYRMVECFLTSGLAGPIVHDALQEAIDEEPPHRDEDLIGLFLKYNTDINTNEGSALVAAVSQKDVRLLNALLKKNVTPHTAAGVLPRIIATQDAKARLDMATLLLTSVPDLDPVKVSQAMLNALNYRPADLKLLQVLLVQGRADVNVDNGIAMASAIHSHDPPVLETLLMHGKPSHATVSRAVSEFGQLIFSDTKAAKLEILLQKTKDRAPFNDVLVKEVHALLQTLPEHRQLSIVKVLLSAGADVNSHNAAALCHAVAASDTQITDLLFAARPNPASLASALPHALRIADPMDRLEFSQKLLDAGAPSAEVNRALGFAINTYTNDIPLLRTLSAKANTSDGEALVSAVKKERPDIVQLVLAQKHPLPVLNDAFAEAALLSNREARAAICEVLLQHGASGSVLSDALLAAAADGDLVLGNLLVSHGAQIDEDAIVEACRSGAADVLNMLLSGTTTPKRSTIERGFQAATEVGNLKTRAAILEPLLIHGVEGEALDAQLASAVRFGEEGDDLVKILLEAGADPNYNKGEAIWAATRSAYLSSLKMMLGLVELGTRLVSKPSSASLRSIASAKSHASLKGSNKRKQHKPSHATLNRALRAAWKLSREPRAAAIDMLFRAGLPVSDDLHVVLNNAINEEELDLKIIRSLLRYGASPIANDCQTLVDATRRALVKPLAFMLESKILSADLNLAIREGFTRENTDAWFSEAGFTILHSFLKKGAHGDGLSSVLTQVVDLPLTESEPDSLALANGFVDILLDHKVDVNYADGKLLQSAAAACNSFLVKRLLDKKPNTESISRSFYRIFDNPASEDDALELITMFTEYADGETRLDVMYTPPDSLPLMFLALQQHPRSIRITKALLDAGYYYDQMMPCKVMEDLDEEAITLMMWALLQPQKKVSSGIVQMLIETGAKVNFESKISQSTPLMLAIRNRRPDVVKMLLLEGAEVDVCDVKGNTPLTLSTEVGGDTAIKMMSNLLAAGASRNDGSLHNSARELNLSACQVLVQYGHEPDFPSTLHGGRSALGELARHCADSGELTAARQKLMERAINFLIEAGSDTTLRSEGKSILLLGLESRDPLVTCRTLLKAGMWKYINKKFNHYSDGKMTYSPTMYVMHVLPKSDQQDALIKLLRANRAEDVYYANMGPQPEGAVGMPEDVEAQERTRRARLDRINLEQEDHALSIARNRELATVQAQIWSAQAELEDSRRQRVAQDELVALNERARIEEDHFAAQMRRKRNERSADLEHQAALTEASITRARAVELAESDLTMARQSMMLEWEKQIATEKVDQAKTLSAIRVAEREDVDRLDREQEERFRARLAEQRRLVDGQTNLASQLTNAGVNGRRQIGYITGEIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH18</accession>
    <name>A0AAD8UH18_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine carboxypeptidase S28-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_579291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364197.1">
        <property type="nucleotide sequence ID" value="XM_060505218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH18"/>
    <dbReference type="GeneID" id="85389117"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000251">
        <property type="entry name" value="Extracelular serine carboxypeptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042044303" evidence="6">
        <location>
            <begin position="20"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="575" mass="63329" checksum="B89009AEC7A22C56" modified="2024-05-29" version="1">MTNWKSGACFMLAAGRAVAAGLGLQHLAGHEAWNALQSAARAESESQVDIASAAFAEQYPEYNLSVPIDHFHNDSRYEPHSDEYFDLRYWFDAKHYRKGGPVIILAAGETDAKERLPFLDHGILSILAKATGGVGVVLEHRYYGKSFPVPDLSTKNLRFLSTDQALADTAYFAKHISFPGHEDLNLTAPGTPYLAYGGSYAGAFAAFLRKLYPEVFWGGISSSGVTAAIIDYWEYYEGARLFSPGDCAETTQKLTEVVDKILLGKSDSDKSQLKDLFGLGPLKDDDFASTLSYGISGLQSTNWDPAQDTTAFGTYCATVSSDSVLFGSTRHLKSSVDELLSASGSDAKLTNRMLNYVGYVKDYVKKGCKSGDLVKCFSGRNSEEHQNTSIRQGPGRSWIYQVCTEWGYFQTGSGVPDDELPLISRLINVDYSSIYCREAFNITEPPNVDAINKHGGFNFSYPRVAIVDGEADPWRAATPHKIGLNRKSTTSEPFLLIDLGVHHWDENSLKPEEVTPDFPPASITNVQAQEVEFVKAWMKEWEESRSQDSAKGGMFSNGHVSFGKLTRAKEVSEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH42</accession>
    <name>A0AAD8UH42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363856.1">
        <property type="nucleotide sequence ID" value="XM_060514318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH42"/>
    <dbReference type="GeneID" id="85398216"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="27921" checksum="CF5F59777EB27E03" modified="2024-05-29" version="1">MRPPLGYIPRLYAPLRLSTRQSFGPSPALTAAATATRSTRRLTFKSRMSTSSGPQSTTMWPAAGQGEGEEERSLNGSGTGSHREHHPTESTSPAPKKTTSNAPAEASPNTSGADSSQCQPHSQGDDQGLAGAQRRDGPLALPPLPEGHETSSAAGGTSAGGRGGGDNNNNNNNNNNGVSSRSSSSSSSSSSGSNTITLDMSRGDASTKLDHLGPLVVNQDGTMSRISNWGEMTEIERRNTVRILSKRNQLRLAGLRGEKEKNGAEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI84</accession>
    <name>A0AAD8UI84_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vegetative cell wall protein gp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_721608</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362189.1">
        <property type="nucleotide sequence ID" value="XM_060512395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI84"/>
    <dbReference type="GeneID" id="85396293"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="634" mass="71671" checksum="2B4FD7B2153B0DB1" modified="2024-05-29" version="1">MSDAGNEAPETSNKRRRTSGMYQRRRAVAACGPCRVRKTKCDNVRPACGFCQRNGGQCTYPDTSNDFSTFDPASLAILDRLNHVVSLLEARPELPAENVVAAPPIPSILSPTSLQGPQTSTSVTIDENLSHSPDGLPEDEVMIRLDIPDSAAARSNCEAILRWPIFRGYAPETESFILELEDGDAESSHQSQPLRSRNLGRGVQEDDFTVLSKKFLAYVHVKNPVLDVSDFKAYVKDTVENGPRWDGPSCLVLIACALACLASPFQSEINFNSTPESMRSSVSATADPDTAQAYYLAAKKRLGLLEPSLLQIQCLFFCAVFEMYSLRPLQGWFYFNQASVQFKNLFWRRAQRRNWQSVSQKTRRLEQRLYWSCMKSECELRCEIPLPPSGITGLGYPDLFPSPPSEVASPAAQPSALDILEDDIQPEEEKSWFYYLAEISSRRMINRAISIFGYNGEQAWIRDIAKVLEKSEEFDEHINLWCLHIPSQIHWQNREPSNNELVHFIQNRATSCREWIHRPFLYYVVHQPADDPWIPRVMPLAEKCLELSLELLLDANPHHRHHGTWFMARAAMTRALLLLTAVKSGRFSRLPERWKQGVDAATWALQRWYGEAPDLRKAASVLEDLVGQVVGPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIV7</accession>
    <name>A0AAD8UIV7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BZIP family transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362580.1">
        <property type="nucleotide sequence ID" value="XM_060514466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIV7"/>
    <dbReference type="GeneID" id="85398364"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40618:SF1">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40618">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="78"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="636" mass="70535" checksum="EECD67319DB26849" modified="2024-05-29" version="1">MQNPGLSILNAESFDDGMSGFRAPRSLPTGGKPGADTSEEPKRSSKKRSKAQSAEVVELDEEEKKRSRGRPRLDTNDETAKDRRRTQIRLAQRAYRNRKETAIQSLEKKVDELRRTNEEMSKEFMKLYDFAVSKGMHESTPEFGRQLQATTEKFVSLARKTSEEPEKEGDVLPSQENDGDAEDVDGPASGRERSNQKSPSAEIAKPIEQVIYDALSSEQPQQHQLRSTPRTHAMTAVHTTSWAPDSQSHMPHSTLSQAPMGYEIVTEPTPDNASFPFGMSYEHSLDQPGTFDLLANQPFSESLFNILSSPTSYAHQERTFGRRLQRSTLEKAYTLLRMPNPPSSLINSAFGFSLLFEPKERIVERIANRLSVNQRETMFNWKFPFLHLGGGGTWFDEMNDLDEMAYPSGHKQRNPVGNQGTAEPYRQKVDSLYGMGPWDAPTEEMRDLRVERAAARLRMNVPGLQGDFYDADEVEWVLRRRGVDIPAAADFVTAEINPADFSDDTAVAGRALGSGLDSNSSSSINNASDIFSSYGTSPGDAAARQWLGQTLKPTRPSDIHLGDTRSVGQSSDAASSQMPLDPSLAGDIFGLESTSTNQTTTSGSKRRAVTINVGVLVQGMFIFPSRDPSTICDRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ96</accession>
    <name>A0AAD8UJ96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_754369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362511.1">
        <property type="nucleotide sequence ID" value="XM_060514469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ96"/>
    <dbReference type="GeneID" id="85398367"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF2">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042161312" description="Hemerythrin-like domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="63"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="297" mass="33330" checksum="74A35DB16D8BCAF7" modified="2024-05-29" version="1">MAGYLLLVIPSILISLLASRAPFMMTTTPQTTKPWADGPMKLITTPQYATKKTDLFTLGSTHMALLHNSILRGYNSIYQQAPYIQEADKADFIGYSQTWFKFVKSHHDDEEESLFTKVEDLLEDKSVFAETHKEHESFLGGLAEFNKYLTSLSSPADFSGDKLLEIMRSFQEPFENHFHSEITTIAGMAEHPNAPKEGTPEAANASLTFKTWGKSTVTKAGTADVVPFFLLNLDRTTEDGLWANWPPMPAPIKWGLINIAGAWHWGWWKFASCDAAGQPRELYALESKMEDNTKAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJJ0</accession>
    <name>A0AAD8UJJ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_627567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362955.1">
        <property type="nucleotide sequence ID" value="XM_060508645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJJ0"/>
    <dbReference type="GeneID" id="85392544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022198">
        <property type="entry name" value="DUF3723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12520">
        <property type="entry name" value="DUF3723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="444" mass="50859" checksum="0CA9D09CB5B4F476" modified="2024-05-29" version="1" fragment="single">MQELLSYLHFVYDTWLQLAGGNESELEKIDWITVEAVQLRCPKFSASDEQALRGIILRGDIFGYFSQAERVAAFAKLCSFDFPIPSLSTFFKDFGYLERCGNSMKHLVPMKRRGPTVRRMLLQSFNPPTLPAQPESPLLDEFDNLEAQFQLAMRRLWLFAMREFHSIRTDPSLLPRFASLAVELGFDNDEIRSLKKLSPHREIARQAMALVRSSQDQDYNSVADEAIIGQIAQAFSGHQHGPKRQTYSAFTTNATTTKMHVRPWLDSKAYLMDRPNLVVEVLDQQPIVKKKEVTSLFLLRSIYKAIFHKDIAYLAGGSRAEPSHSENHQHVQNHRTKESRDHAATRHADSTVTLDSTNTRTRRVRLQITQAGINREERHVDINLDDRNGPNQIGSIIQQLMVQYRVLPFSPMGYPLLAEECYGEIVRKGHDCLYLTDDKRGKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKN4</accession>
    <name>A0AAD8UKN4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_581509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363171.1">
        <property type="nucleotide sequence ID" value="XM_060505465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKN4"/>
    <dbReference type="GeneID" id="85389364"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="14"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="559"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1036" mass="113349" checksum="5332668AABEC5AB2" modified="2024-05-29" version="1">MASVAQDFDHPIIGKVKGQASDGVIQFLGLKYATLQHWFDNAKLAQYDGSGLNATRHGSQAVSDPDGVKNEHIIIQKSLPIPEFPGLSGTECLNLNLTAPLEIGDLKQVPVLVFIHGGGFGTGSNWWPQYDTKRIVQHSNKLGKPIIAININYRLGIPGFLTSEELRKEGFKSNQGHHDQRMALEWVGKYVSGFGGNPQRVTVVGESAGGISAGRLLYSEKALASQLIILGGSPPSLAPLDLGVAEQAYTGVLKALGAGDVSSSERIKILSRASPEELSSKIGRTLPFLPVLDEETVPFVPTFETASAGKLIPKTTSCKAIMVGYAPLDASIFGFMGLFQRKENIAASFTQIINTALSHHAGIAAQILQAYDINDTTNDDEAFIRILQFASDIGFRATAESFANSFHGDSYLLEFAEPNPWEGPFRGYSTHVLDVAFLFQNYKEYLGEEQRKSAESFVTDIVDFVHGQAPWRRFQGAGGRMVYQDGTRAYKEAGASTTRYDLLLELGEKIGLDTLLKGWEAFLISVTLFVLSYAIRITMAYTLESKSLGSTLCGVDLGTIAQFRGIPYGKIVSRFAKPEPLVALPQSINCTEFGPRCPQVKVDVGHLLRIPPEHRLPVEAEDEFRCLNLDITVPKSQELLRAQRLPVLVWIHGGSQAVTFGSAASGVCDTRRIVEDSVSLSKPVIVVTVQYRLNIFAFGSESSSSNLALKDQSLALRWVTDHIPDFGGDPNDVSLAGESAGAVYCHAHIATGLRVRRVILSSGSLYLSPPQPRTKASALRQTLVNHLGTLGDFDLSTAPVEKMVKAMELAGIHSWFLQVDPTLVGWETTIGAAESVMIGDVRDEAVLWREGVWKMEASDIAQAFNYAGEHQDTLKKLYNIHSDRTSASKIGALDFMNDYKFLLPAENIARLFRAANKPAYRYLVDECNPWQPSNGAHHAVDLLFLFGGFDLSFAPGAQQTGKQMRKSVIEFIHAQEPWQLGSYAAFGPYGMFQELDSVGVKLRRRSEQAEFLHSVPSEMLDKVFFALAAGRISLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULD2</accession>
    <name>A0AAD8ULD2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_302751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365518.1">
        <property type="nucleotide sequence ID" value="XM_060502264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULD2"/>
    <dbReference type="GeneID" id="85386163"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="224" mass="24732" checksum="A0D4C6773218FE9A" modified="2024-05-29" version="1">MCQEPQNQSPTPRQPLSMQSSSETQTCYSICCERSVAVERKRERKRAVGSLPSNRVVWTRDADSDRGPGHASGRLGEVWQWKAGTWNARNNPALLPANRNSPLKKHPSKSPETCCLACVCCPPLPNRLLKTTSGAEYRREGARASTDAEAQASICSSFSPVWQARPSLAMQQYHKRNANQRAASLLSICGCWLASLSLHTSTGLLRLQHAGESIRTAMSELRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM48</accession>
    <name>A0AAD8UM48_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_263016</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366406.1">
        <property type="nucleotide sequence ID" value="XM_060502011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM48"/>
    <dbReference type="GeneID" id="85385910"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1726351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="336" mass="37304" checksum="3B9D490DC22610C1" modified="2024-05-29" version="1">MSGFGDFTNICHMAPLPLCASIGPITEVTSGVGIEPDCYARNIELANTIIFEGAASAMHIVSLLMTVVMILHIRGKFTAVGRKEILMFFYIYMLLSFISLCVDAGVVPPGSDPYPYFVSVQNGLSSALITCLLINGFVGFQLYEDGTFLSVWLLRVCSLVAFAICFLVSLATFKSWAGLGPTNTVGLFVVLYLLNAIELFVYVALQILLVVRTLQDRWPLGDIAFGIFFFVVGQVILYAVSTQICTAVSHYLDGLFFATICNLLGVMMVYKYWDSITREDLEFSVGTRMNNWEVKELLPEEDRRATVYDNDPYNHTGGYDHSYSPSPAPARYSARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM92</accession>
    <name>A0AAD8UM92_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_793995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363020.1">
        <property type="nucleotide sequence ID" value="XM_060515795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM92"/>
    <dbReference type="GeneID" id="85399693"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="167"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="347" mass="38933" checksum="F6745FB7927A2262" modified="2024-05-29" version="1">MSVSEHPEIDGALVEERLTSLGDDSVAQLGVTVALNICDDYVPCGKSDDTDQVLKIFLRRLEGNGLTTLAAEVYLYQNEPDKLRALRNHLIDALLKPMLARGRGKGVISQPVDENAQTEIESSLHEVETVQRDEVLRRDCLKREGGKCILSQYWSRSWEERPSEGAQCSTKCAHCIPFSLSTTNGSYTQTLNIATIWHAYHRYFTDLKGAIASDSINQISNAITLMDTLHKQFRRLEMAFKSTDVQNQYAIQWFGAGEQFFLRWSLPSTVQFSAHNGDENLPNPAFLRCHYILAEVYNDMNLQNHSLKVLPILPPDEKMTQNDALSFIGGAGDQPVEATAQDLQLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMJ5</accession>
    <name>A0AAD8UMJ5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_719809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364619.1">
        <property type="nucleotide sequence ID" value="XM_060512212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMJ5"/>
    <dbReference type="GeneID" id="85396110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00877">
        <property type="entry name" value="Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000131">
        <property type="entry name" value="GTP-binding nuclear protein Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1724564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="24398" checksum="C63CC333DDD024CE" modified="2024-05-29" version="1">MAETQTPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYMATLGVEVHPLGFSTNFGQIQFDVWDTAGQEKFGGLRDGYYINGQCGIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLVGNPALEFVAAPALAPPTAQVDEKLLEQYRQEMAEASNMPLPGELSDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMX8</accession>
    <name>A0AAD8UMX8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynamitin-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_624475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364084.1">
        <property type="nucleotide sequence ID" value="XM_060508445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMX8"/>
    <dbReference type="GeneID" id="85392344"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="46696" checksum="10A6901CB7345C84" modified="2024-05-29" version="1">MALNRKYAALPDLDSAPDVYETPELTDDTSTVPTTTGQSHSDDDFDDDLDDDANGISRSRLRVDEARSRFLPAGVDATGVDFSDRVDGKRKSYKASTRRQRFLQDGTEQFGDLSDEDEEDSLERKIARLQREVEEAKEEYGKRKEAAAKPTTGDHDEKLGSLSKVLDEISKTLEPHTSASRALQPVSQSSGPSKNESQDLVAPGSSATYTVTYAPTYEQSHALATAADFDRRLVLLEKAIGVGSTALPEVDINGLPRAILPTLDGLQKQITTLSQASTSNLDSISRRVRTLIQEAQELEKARQGAKSAQETLGNGTASSEDAPAPEQLAKINALYGTLPAIENLAPLLPPLLDRLRSLRAIHSDAATAGEMLGRIEKQQTDMATDLKQWKDGLEKVEEAMKEGGTAMTGNMKVMEAWVKDLEGRIAKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN56</accession>
    <name>A0AAD8UN56_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_278785</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365942.1">
        <property type="nucleotide sequence ID" value="XM_060502117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN56"/>
    <dbReference type="GeneID" id="85386016"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF189">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="17"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1725887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="533" mass="57704" checksum="38B58D06A5846F73" modified="2024-05-29" version="1">MFNEQTNYVSKVKVITIFLACASVDLVALMDQTTLAASLSIVGNYLHAGQQLSWLANGYFITSTVGQLLYGRLSDIWSRKVILMVGLAIFGLGSLASSLAQTATQLIVFRCFTGLGGGGLMTVAQMIVSDVVPLRERGKYQGILGAVTALANGIGPVIGGTLSSKGGDSWRWIFRLNLPLTALSAGCALFFMPLRKVEGDWKVKTRAIDFIGILLALAGTTSLMLGLTWGGGEYPWASAAVLTTLIVGAFICVVFVSWQWKGPRYPLVPLDIFRARMTIGACITMAINGWNFVVQVYYIPTFYQLVYNYGATRSGVMLLPITLVQTASSTLSGLIVHWVGRYRECILFGWLCWSVGLGLMSTLNEASGLGKQIGYSLLIGVGVGNTLQPALVAIQAGVPRKDMAVVTSFRNFVRNLGATFGLAICGTILNNIVKNSVNSLDLSAERRDSLLTNPQQYLSSLSREDAQRIRDVLAPAYQRSFKVIFELGSGLAAAGFFVAWFLMPHIDLARPDDHKLKEEGHQAQLKGNAEKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNR7</accession>
    <name>A0AAD8UNR7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_385567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363695.1">
        <property type="nucleotide sequence ID" value="XM_060502740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNR7"/>
    <dbReference type="GeneID" id="85386639"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="2">
        <location>
            <begin position="78"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="258" mass="28978" checksum="83EC0F4F20FDDB00" modified="2024-05-29" version="1">MNEIRAKALAEKEDEVNAFATLSDAETLRSLEGSFARMSIQSSQTLSEDGFKEILDRLCVAPYYRHHHQFIAQSRLSGAGQWLLQHEKFVAWQNSSSSSLLLIHGIPGSGKSTLCSVFVDSMLSMVSKTSTAAPFGYFYCANPQSEKERRSADDVLRTILFQVSIDPVHRTKLKACLDCEYERQVALARAGKFDLAKLYAPDCVRLILEIAEQDPMTIVIDGVDSVDEIERPVIIDALLSTSHEMFLWARLQVERICR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPP3</accession>
    <name>A0AAD8UPP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipocalin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_623811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000055">
        <property type="protein sequence ID" value="KAK1724180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364235.1">
        <property type="nucleotide sequence ID" value="XM_060508405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPP3"/>
    <dbReference type="GeneID" id="85392304"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19438">
        <property type="entry name" value="lipocalin_Blc-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047202">
        <property type="entry name" value="Lipocalin_Blc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041785307" evidence="2">
        <location>
            <begin position="19"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="52"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="201" mass="21255" checksum="83CCF6033EE8424C" modified="2024-05-29" version="1">MRSSTLSTILSWAAVASAVAVTNDTSPSPSIPNVVQSTWDGKCFYPTPDAAFDLESYLGRWYQVAGTVAPFTAGCKCIFAQYSLNDNGTVKVNNTCEAGGRAINILGTAAPADPSYGAKGVLRVQFPGQPGPDCAGPNYIVQDYTPDFALVQASNFTTLFVLSRQRNPEDAVLDAWIARAGQLGSNLADVVKTDQTGCQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPU5</accession>
    <name>A0AAD8UPU5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_717829</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367348.1">
        <property type="nucleotide sequence ID" value="XM_060511991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPU5"/>
    <dbReference type="GeneID" id="85395889"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000097">
        <property type="entry name" value="DnaJ homolog subfamily C member 7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000055">
        <property type="entry name" value="DnaJ subfamily C member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052758">
        <property type="entry name" value="SRC_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="548"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="703" mass="75836" checksum="42FD206E4397F0A8" modified="2024-05-29" version="1">MKLFAKKSSKKQGQDDDDNHQESSYFPSSEASSPTKSPTKPRSPIKSPTKSPTKKPSQPASPGPRETKPSRTSRTFGRHPTDPGSRRSSKIDLDSHPLNLPPEERAKRLSALSAMSGNAMDIDRESSAAPSSPPAAAAAAAAAPQPSAQTSFSVPKPNGINTNVNGNGDAPAPPPHKSNPSSPVPTTEDEAEAYKAAGNKFFKEKDYKNAILQYSKAIELVPDSATYLSNRAAAYMSNTQYEYALDDCTRASDLDPENPKILLRLARIYTSLGQPQEALLVFGRINPPPSAKDQAPAKEMLKHVNAAQSALRDGTAGSMVLHALDQAERQLGFGASRPRKWQLMRGEAYLKMGTVNALGEAQNLAMGLLRGNSQDPEALVLRGRALYAQGENDKAVSHFRKAISCDPDMRDAVKYLRIVQKLDRMKEEGNQDYKMGRWQSAIEKYSAALEVDPANRGTNSKILQNRALCKIKLREYDAAIADCERAISLDSTYLKARKTKANAYGQAGKWEDAVKEWKNIQESDPEDRSIAKEVRRAELELKKSQRKDYYKILGVEKDADDNQIKKAYRKLAIIHHPDKNPNDEQAAERFKDIGEAYETLSDSQKRASYDSGEDLMDPSDMFSHGGGMGGMGGMGGMHGGIDPEILFNMMGGGGGFGGGGGFNGGGFPGGGGGAHFNFADGGGRPRGGGGAGGFGGRGFNFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQM1</accession>
    <name>A0AAD8UQM1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial alpha-L-rhamnosidase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_750331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367127.1">
        <property type="nucleotide sequence ID" value="XM_060513906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQM1"/>
    <dbReference type="GeneID" id="85397804"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Maltose phosphorylase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035396">
        <property type="entry name" value="Bac_rhamnosid6H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987:SF2">
        <property type="entry name" value="B, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34987">
        <property type="entry name" value="C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17389">
        <property type="entry name" value="Bac_rhamnosid6H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-L-rhamnosidase six-hairpin glycosidase" evidence="1">
        <location>
            <begin position="388"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="831" mass="93797" checksum="860E921E8D38F2C5" modified="2024-05-29" version="1">MDPQLLDTPWIWHPEWQDHGANTAGGIVHFRKSLKLKEVPHGPSKIQITADTRYKLFVNDQDVFSGPVKGDEHLWFYDEIDIQPFLKVGVNCISVRVLRFFHATQYATSFPRLPIPGLFVRPLAANDGVPLPVRSDSSWEAAIDRATVLRIDQKEDDFLHVYEDVDARKALELAWVSAKQLELPTSHGITPPWVLSPRMIPQATTTSQSIAAVHNVKSSISQASWESFFKDGASTLRLPAGTHHHIEVEAEIHLTAMLTFRFRRSKTSGSTLRVRYSEAYEEEPEYVPYIRRKGDRRDTTKSLFGPEDKYIFAGSSGAHASSEIAYGLDAAEFETFSPFHFRTLRFMSIDIQVDPESGLEFVGIVIDQVHYPLEIKSGLTLLSTDDHQKTYQRLWENSARTLTNCMHDCYEDCPFYEQLQYAMDVRSSCLFTYFVSGDDRMARQAIVQLHNSYRPSIGLIASRSPAHVFQVIPHFSLFWICTVADHFTHYGDGDFTQKFLAVCDGILSSFTQRLNAETGLISSDCQSVKTHWDFVDWTTQWRPMGIPPAAQRTGTQTFTNFLYAYTLKTIAETVRDLGRPALAQEYSSRAEDIISATQKHCRVGTIFTDGLAARADHSLDFSQHNQIWAVLCGATSGEEARQLLTQCFNHGSRASNLSTTSGQPITFTKVSTAMSFYALRALSEVGGDLYDKAFHSFWDPWRHQLSQNLTTWCEDEVTLRSDCHAWSAVPLYEFTTEVAGIKPLEPGWRAISCAPRFNLFSEFDAKVALGGELAPGIARVRWSREVGTDELSLSVVLQDIPVEDSIRVSVKLPSGVEEHFGRDLKFNLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR72</accession>
    <name>A0AAD8UR72_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_610791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368023.1">
        <property type="nucleotide sequence ID" value="XM_060507611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR72"/>
    <dbReference type="GeneID" id="85391510"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="88" mass="9478" checksum="562D63A30D754D07" modified="2024-05-29" version="1">MQLSARRAPSPATPSSERRGALSWPAGKHDSKKHAREPARNGRHRCSHQCCKHPIRATLGPTFTDRLTNVSPAHDAPLADDDGDSGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URG0</accession>
    <name>A0AAD8URG0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_750041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367547.1">
        <property type="nucleotide sequence ID" value="XM_060513866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URG0"/>
    <dbReference type="GeneID" id="85397764"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12467">
        <property type="entry name" value="RRM_Srp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000123">
        <property type="entry name" value="Pre-mRNA splicing factor (Srp1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034403">
        <property type="entry name" value="Srp1p_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="195" mass="22968" checksum="938B0869691F1E43" modified="2024-05-29" version="1">MSRGGQTLYVTGFSHGTRARDLAYEFERYGHLVRCDIPAPRSASSRLFAFVEYEDRRDADDAYHEMHNKRIGRDDILKIEWARTPPSASWRFDSGRDRERAPRRSSPRRGRSPSPRRSTRDYSPRKDDRRDRDRDYDCSDRRDTRDRSRSPDRRDRDAKEDREDREPRENGTNGDDRKALDSPPPAHDDLDVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URI9</accession>
    <name>A0AAD8URI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_752095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365165.1">
        <property type="nucleotide sequence ID" value="XM_060514145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URI9"/>
    <dbReference type="GeneID" id="85398043"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000002">
        <property type="entry name" value="2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="80"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="34630" checksum="E7D84693573B4280" modified="2024-05-29" version="1">MITPRWKRLVRFIAEDDWREYIGEPVDETVDVGAALAASLPVPTRVFTGISALDASAEPTPRILTVQKLLPPLTRKEIGTIRCIGLNYRKHAKEMNLELPEHPTLFFKPASCLNASNAPLLIPHQATDLQADYEAELAVIIGRDARNVSVEDAMDYVLGYTCSNDVTARKHQFAGAQWGFGKGFDGFAPMGPCIVSAGSLPDPSVIELKTVLNGEIMQEGRGDDMIFSIAEIVAYLSQGTTLEAGTVIMTGTPHGIGVSRTPPVFLAPGDDLRIVMSHGLGSLVNKVEYEENPQKNMNGANGVKAVNGVNGVKEVKVNGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URU5</accession>
    <name>A0AAD8URU5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS0</name>
        <name evidence="10" type="ORF">BDZ83DRAFT_611666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URU5"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000010">
        <property type="entry name" value="40S ribosomal protein S0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032281">
        <property type="entry name" value="Ribosomal_uS2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16122">
        <property type="entry name" value="40S_SA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS2 C-terminal" evidence="9">
        <location>
            <begin position="205"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="294" mass="31714" checksum="C44310CCD6A8A3CE" modified="2024-05-29" version="1">MAPANLPSIFNATSQDIEMLLAAQAHLGSKNLQVHMEPYLWKTRADGVNVINVGKTWEKIVLAARIIAAVDNPADICVISARPYGQRAVLKFAAHTGAVAIAGRFTPGSFTNYITRSFKEPRLIIVTDPRTDAQAIKEASYVNIPVIALCDTDSPTEYVDVAIPTNNKGRHSIGLVWWMLAREVLRLRGTIYNRETPWDTMVDLYFYRDPEAEAEEKVEEEKLPGVEEEGVAAIESGFPATGDWDAQAPGFTGAQAGANWDGAGDEWAAAGAAPTGDWAAAGDAAAAAPKESSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU44</accession>
    <name>A0AAD8UU44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_573030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367204.1">
        <property type="nucleotide sequence ID" value="XM_060504581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU44"/>
    <dbReference type="GeneID" id="85388480"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="760" mass="85141" checksum="5770ADC65969515B" modified="2024-05-29" version="1">MEAAAKKVQLLAQRILPDRPHSLSMNPDQRFRVPPDHSKTFEEFKFPALQYMTLLSDADRGMLLTRAYHDMREEPPIPPAVKDSNAKMEKKNVTKLSLSDYKNKQKKVSDSPPDSGSTPKTDVSRKERNVVESRIDREPKRPDAYRNREPDASRDVKAHKARDGAHDERTSRPDARSRAAQDSNDTPDKRKRIADVDGELRPQKRARPEASTPLDERSRTPRDDTPRRKEIHSSQDRTPQKDGKFGTSSSSLPNGRSALKTAFGSGANKSPISRARGDSINGNKPSPSSSGRARADTASSRSAVPPLLSPLHLPNESDSRSKEKRRDDPPEHNRPQKSSRAEPPPPIKRPKSPLKLPELLSPTLPPLLEEELARMKNTPTKGSDASQRTQPPDSPTNGKRPHVVVKEEEDDRKEVKGKEKPKEKPRRFMVTLKYSKKYTKSVQRLLALGPPRKDIKKERSVSIEPPPPQARKRPITSTENVGDSIAVKRPRTSEITSSKLNAPSTPSKGGATSMSRVASSNSVNTPGDGHSLTPAPPSSDRDRPQTRDDSREAANPHRVQALRDRWNRFSRLGTKLKHERDILLERKHGDRGAPVSDSDIKLSMMLGLETAMAFMVSFRALFESRRIENKAQDPKQWSSILPLLNVMRNDVRKSKPLEALFWQMQGVIHEELIKCYWSLDPATHALHIIGAERGRSNVWKSAYDSAERVEASSMRTNMGPWTSVEEAVSSALKIMRRWAHEEGVSWRAEVTVSAANGTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVN2</accession>
    <name>A0AAD8UVN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Piwi domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_748957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368594.1">
        <property type="nucleotide sequence ID" value="XM_060513696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVN2"/>
    <dbReference type="GeneID" id="85397594"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="759"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1728539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1109" mass="122077" checksum="D981C0A1CD5557FB" modified="2024-05-29" version="1">MADSGRGGRGGGRGGRGGDRGGRGGDRGGRGGGGRGGGDFQPRGGGDGGGFRGDRGGGRGGFRGDRGGRGGGPGGDRGGRGGGFRGDRGGGGFRGDRGGRGGFDRGGRGGGGRGGYSGFRDPFENESQFFGQNKPIPQPDGSTTELENRIVKSHQAKDTKLVEKMSSMTLIEASSAALMPRRPAYGTKGKKVVLWANYFHLTVNPDAVWRYNLEVRKGESKEKEFTPKDKGKGKEKAQPGGGGSSSGGGGSDGPPSSIPARKLKIILQAALEELKNLEPNAILATEFKSQLVSLKKLKLAVNPIKVIFKQENSDRSESYLVKIVGETAAPLKEMKEYLQTMVDKSDPDEANFPRFAASVDALGVILGYTPRKNDQVTAIGKGRFFPWGQGSTSHQLGQQDPLTAIRGYFQSVKLGTGSMLLNVNVTHGVFKMPVSIRDLCLWSQVDVFQRSPADATRNITRLRALSKFLARTRVEIKFKDAKGQEITRKKTILGLAYRGDLRGNDARIADPWHYGGPRQVSFRMEPADGQRTVMNNRPPGMYTVEQYWTWKYGTAPDLTLPLVNLGTREKPTFFPAEQCTIIPGQAVRAKLNGQETTEMLNFACRSPFSNAISLTFDSCKALGLDSEVVKDFGLKVDKNLLTVHGRELIAPNLAYANRNITASKGSWNMVDVKFAKVGPNISRWTWVRIKDRYSRNQTSDVRQIVGNFVQFLKISGMSITEKPLPLEDHEREIDDNLSTIERYFTWIDGRLQQRTKGVFVLVVLPRQDTALYSKVKTLADTRFGFHSVCVVEKTFMKDNKQTYANVGLKWNLKNGGVNHIVKDPIDIVNQGKTMIVGYDVTHPTNMPNDKNAAPSLVGLVASVDKDMGQWPGAAWEQDSRQEMLGDELITHFKRRLELWRARNNGNLPEYIVIYRDGVSEGQFTQVLDIELPMIRQACAAMYGNRRPKISIIVSVKRHQTRFYPTSEANMDPKSRNIKNGTVVDRGITQARYWDFFLTAHTALKGTARPAHYTVLLDEIFRDKYGVGDRAADNLEKLTHDLCYSFGRATKAVSICPPAYYADIVCERARVHRPEHFDASEASETGSTVGAPSTLSVSVHENLKDTMYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW01</accession>
    <name>A0AAD8UW01_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparaginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_572671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367355.1">
        <property type="nucleotide sequence ID" value="XM_060504536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW01"/>
    <dbReference type="GeneID" id="85388435"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04323">
        <property type="entry name" value="AsnRS_cyto_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048952">
        <property type="entry name" value="AsnRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF16">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20917">
        <property type="entry name" value="AsnRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="278"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1727300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="583" mass="65727" checksum="FB3ABCD2CF10888A" modified="2024-05-29" version="1">MAAPQELAERPKTEDKVYIDTDAGADEPSTQGTESSPFKSLAAAYIANNESVTSRQFLTRASKTGDDEAARLEWKEPAKSAVKKAQSALDAHRKKLVKQAQIEAKEEEQKKARQQALEAAKQIVIKEDESLPEAKRITIADKTVVLGEGDKKGDRVKIAGRIHRLRAQKQATFITLVDGYGHLQCVLQAGDLTKTYDALTFAQGTSLWVYGELKKVPEGQTAPDNRELHVDYYKVIGTSPTDEDAITNKVSLLQNQWDSQMLDNRHLVLRGDNASAIMKIRAAVEWAFTKTYKDLKITKVSPPALVQTQVEGGSTLFSVPYYDEAAYLTQSSQLYLETVLPSLGSVYCIEKSFRAERSLTRRHLSEYTHVEAELDFIEFPDLLAHLEEVMCRVIDNVLADEEIAAYVKELNPDFKKPVRPFLRMKYTDAIDWLNAQDPPILNEDGETHKFGDDIAEAAERRMTDIINKPIFLTHFPTEIKAFYMKKDPNDPRVTESVDCLMPGVGEIVGGSMRMEGYDELLAAYDREGIPSKDYYWYTDQRKYGTSPHGGYGLGLERFLAWLANQHTVRTTCLYPRYMGRCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X843</accession>
    <name>A0AAD8X843_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_184325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000218">
        <property type="protein sequence ID" value="KAK1706954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357954.1">
        <property type="nucleotide sequence ID" value="XM_060501544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X843"/>
    <dbReference type="GeneID" id="85385443"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015368">
        <property type="entry name" value="UBA_C_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09288">
        <property type="entry name" value="UBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1706954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="237" mass="26309" checksum="C5CC54914F2B183E" modified="2024-05-29" version="1">MSGPSPRERRIGKELMDIRNDKDNSGVFAQPLDEANLLHLKGSFPAPPDTPYAGGLYEVDIKIPDSYPFKSPTIKFITKIWHPNVSSQTGAICLDTLGSGWSPVQTIKTALLSLRMLLEFPNPKDPQDAEVAKMMLENPEGFAKKAHEWAVKYAGAPSKDFDTTKYKQVASEVKEDDANRYAGYNKDLIDRFVGMGFELDAVVEAFTFIGIDRNGGMDYELEEAYLGDITAHLLGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8H1</accession>
    <name>A0AAD8X8H1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_642048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000193">
        <property type="protein sequence ID" value="KAK1708662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358344.1">
        <property type="nucleotide sequence ID" value="XM_060509589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8H1"/>
    <dbReference type="GeneID" id="85393488"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000435">
        <property type="term" value="P:positive regulation of transcription from RNA polymerase II promoter by galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051127">
        <property type="entry name" value="Fungal_SecMet_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424">
        <property type="entry name" value="REGULATORY PROTEIN GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47424:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR ASQA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1708662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="742" mass="82819" checksum="A4DD18AEDA2A5CB0" modified="2024-05-29" version="1">MANSAPRAQLAENRSRSGIRPKRRQVGRACDACRLRRIKCDDASPCANCRGRGQQCSNTEATRTSTLSQAHEEIDRLRLKVLDLERELQRHRGAHTNPETPFSLHSQQVVANVEATATSNIEVHFVTPKNKPWDGALLRPARSPHVAWFGPSSLYFFIHRLGVFLSTDVEHAQPDHMLLRSTSGSAVPAQSRTTSEDASHLLRPLFNGNKPGVYLNPIQEEYFVNLFWQSYHTSLYAIVDEAEFKKEYQALYLDVPPGYTRKPSALVDIVVAMCMQYMASSLPSSHQGNIVEGNDATTAGRWHYRRAQTLLAGEMESPTISTLQCHLLSAVYVCGASFHNMADSICGQAVRIAYMLGLHIDPPLDTPEKERQVRRRLWWAVYVLDSKVGMKLGRPFLLHGSFFMPPFPDDQLGASMLSGSTFAPISGDATWLSFSLHHLKLFKTMRDAHTTLYSHDVGLGQHKTIWDDPTSLAKVAESLEPHTVMIERWVQNLPGALKNSRVNNGRILSTDGSALVIEQYAPLWLQRQRLLLEMEYHHMSINLYRPFISFKRVPAVGSLLETVAVESINHAIELSKITQQALSSTAILDGWHEAFQWQWNSAITLAGFILANPRHSAVVSARSAMDLALSVFSTFGQSFELAKNAETVVRMLCTKIDGLISASSQHYGQKEPAELSTLRIGQEVEVANDFASELTHTSTSPELLTQFPEFDFTEMAVGVDFWANIDMLGVGDINTFGESSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8L5</accession>
    <name>A0AAD8X8L5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_592153</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358479.1">
        <property type="nucleotide sequence ID" value="XM_060506508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8L5"/>
    <dbReference type="GeneID" id="85390407"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042248042" evidence="2">
        <location>
            <begin position="21"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="36"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1709140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="432" mass="47865" checksum="303A28551FF6CDB3" modified="2024-05-29" version="1">MSPKAFFWLLVPSYIARIFGHATENSIIPAPNKTSYLNGLRGIASLIVALQHTIDGDYPLIHRAWGDSEESVYVVQLPFIRLIHSGVFMVSVFFVISGFALTYGPLSKSYAAQGAQGAQGPNPISSFPSSIFRRPFRLFLPTIPIIAVSTALVPFSAFYALNSTEPMGPVAEGFWSHVYYVWTTLITIITSGSANTVMPQGWTLAAEYQGSLLVFLACMAFIRMSPMVRLPATVLLLIYSFNLQRATNCLFIAGMFIADLRLFRAKLPELPKMVRTVVTVTSWLMLVPIIFLGCWPMHGDATQAPIYSWFAGFNTFGFGVHQFFQGTCAVALVLSLENLPVLQHVLNTKPVLYLGEVSFSFYLVHWGCGKNFLSYGLKLKMLAAGYSLIVSWGTLFVVAMLSIIVLGDLHWRLVDQKSVTFSHWLAKRLGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9A0</accession>
    <name>A0AAD8X9A0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_591348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000170">
        <property type="protein sequence ID" value="KAK1710558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358837.1">
        <property type="nucleotide sequence ID" value="XM_060506428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9A0"/>
    <dbReference type="GeneID" id="85390327"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF7">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042007741" description="DUF1996 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1996" evidence="3">
        <location>
            <begin position="37"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="517" mass="55743" checksum="5436E45AC148CF44" modified="2024-05-29" version="1">MKLSNTQALALVSALITSAEAFWRMECPGRVGLARVDPLMSFGGAAPHVHAIHGSGGISPTADFGDLTASDCTSCRVKQDKSAYWHPALYFQDSATGEFELVDQVGGLLAYYLLNGKDIKAFPPGFRMIAGDTNRRNYTAGDPSKPDPQKSEWAILGQTDQSVLRQRAIGFNCLNYGRDPEGTLYRHFLPDKTYLDANCANGVRFEMMFPSCWNGKDVDSTDHKSHMAYPDLVIDGTCPDGFETSTPNLLYEVIWNTYAFKDRSGRFVIANGDTQGYGYHADFISGWDEDFLQSAVDTCTNLSGRIEDCAVFSLQDEATSKQCEMKVPDLVAKDNVTGPDAQLPGNCPITYADGSSEGGDADPVSSTSSIAAPTVPTLTYKPGKTATSNPLPGEVFKETGKIPYGSSSSVSETVAAEAVATPTPEPTPTPELTPTPVFEPITTSTPASSSAPGMSCVSTQTITAVNTVSIICWEEDIVYVTEYEDITSTLTVTPTPSASVPAMRAKRHLHQHRHHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAW6</accession>
    <name>A0AAD8XAW6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_91923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000142">
        <property type="protein sequence ID" value="KAK1712960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359576.1">
        <property type="nucleotide sequence ID" value="XM_060516007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAW6"/>
    <dbReference type="GeneID" id="85399905"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
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            <begin position="557"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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    </feature>
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        <location>
            <begin position="626"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="648"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="684"/>
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    </feature>
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        <location>
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            <begin position="829"/>
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    </feature>
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        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
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            <begin position="899"/>
            <end position="908"/>
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        <location>
            <begin position="938"/>
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        <location>
            <begin position="973"/>
            <end position="989"/>
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        <location>
            <begin position="1195"/>
            <end position="1207"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1712960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1207" mass="128212" checksum="AA7F8B37EA2D8090" modified="2024-05-29" version="1">MMATEATLAAPVDASVHSDPKLTNDADIDSQNVGPNRARLNGSPAVDDLENKHITGVEDQLNSADVSVSGGSDTEASRAARDGEKGHDRTSSTVKKPATFKAVSVNKTFLASKGPTISSTTKPGEKTNSTSILSSSPSGTSTLSSRPRLVAKSGTGTGSSPGLKAAANGAKPASGPDPSAVWNKNRPVPTPEPKKLTDEELKKYGIHMASRLAPESGQSAQGNWADIEDDDDDWAPETITWTDGTKTTLPHPDEVPAPPPPEPTPAPPKEKVIEKPKSPVPPPRITASPSIKTGGLASGRGLILKAGSAEKPTLVAKPPAPPTPVKSPWAPLPPVEKAPPPVIAEPPAPQQGARYPPRDPAINNNAPFYHAKEIAADDFNRSAWREGAPPGGNRELFNSQSGRYEPVPTDRRGSFRSDVHPRQPALLQRPSQSDHPEPSAAFQTSRSSVPDGPMGRRRGSSVASGGSGSYLQRPGKGHELPGPPQDLLSARRGSMAGSVESPISPRNFSPSGLQHGPRMHGNQQWQPRPSPGTNHATLHSAGPQTDGRPAAPPPMARLEEDLEMQKKVMREKRELAMQRRREEEAREEAARKARIAAKLEAMGPPPERKSDKKEASPESSNAAPAQTQSRQDGSINQEAGSQPPAASPDTSAVPSTPANTKDKPYGERPVTAGGEHARRPSGSEARQPNSWVAPTPQQERLPTWGAAAAGPQAPRNVWGSPNNDRGLGNGTFNTDLGRLPEPQAAGKGPAPIAPPSSQRAQVQVPPVPQARPTTGNAREVNEMRNRWAHSVLEGDKIVLDEKRSQRLERDRSLAERGLTIEQAQATIKDTWRPSGDGRRDPAHVIHHDVARAAGSVDHPSVLPPTGPSAATQSRSSSRFFPPKDVRHDSSASHAEPSRPSSPSPPPPDMLGHPAFDGDAMHPHVSLPRPHPVVKLPPSAAAAQSAAARSTGPFAWATPAGYKDGPGTHGRGPYQQNHVSQRSQDSAGNENWQDRINNLLTGRKPNSPPKAPGVEPVTKSALDYSGHYNPATVSLPRSATQNLSDDVKSFTTKPPAEECFEEQEMGSLPRIHLPHKTPEAAWQPAATPIKPLPRRFWVSDIETVRSLWFPHEMSTSGSVYRILLPGMGDARTVPLPFSRSGSNPRRSSGRGGGQRGSGPNHRGGKGREPSYSGEASSSTPPPSRGGRGGYRGRGSENWSRRATPTQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAY8</accession>
    <name>A0AAD8XAY8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_41384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000114">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980340" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13252" checksum="D6871E4DAF1630A6" modified="2024-05-29" version="1">MSLSAAAWFISFLFPSSVPAWPQNICDVCAVPRNIRGSYGRDGCWFQDGHAACRHLSFAPHFRYSSKSSAICLPLPPHTIRAAGLSTLNLTRSPSDEDRDRGAYVAQTSKRQISCLLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC00</accession>
    <name>A0AAD8XC00_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_641876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Colletotrichum acutatum species complex</taxon>
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    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
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                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_060509579.1"/>
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        <property type="entry name" value="HET"/>
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    </dbReference>
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        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
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    </dbReference>
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        <location>
            <begin position="64"/>
            <end position="215"/>
        </location>
    </feature>
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        <location>
            <begin position="484"/>
            <end position="510"/>
        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="58134" checksum="636004704A859849" modified="2024-05-29" version="1">MSANESKRRSEPRPLDKTTAFNYQPLEEMIECTRFLSIHPAKDDSDPIISCALNHIAFGEKPSYEALSYRWGEEASVHTIILNGHTFLVRKNLYDALLYLRSRGNCGLLWVDAICIDQENVQERNRQVAIMRHIYFRAQTVVVWLGSSYSQFQEEMGPLEARFASEESTMDESPTTATEFGDPDDGHAASLECEREMVLRLAKDEYWNRVWIIQEIGQARQRRVCFGNMELSWGNFIRMMTHHSVTTEGPLRLNQQVEQKYQGSHTLRRLLYDHQKSRCQDPKDKIFGLIGLAVDGRGYPSPDYDKSLLQIWTETMEFMNSRRMFDDKNELDIVSHATLIKFLLMGTRSTPIQQILGPYVAEPEKQLISLQHGYIHPHAFKLTGYLLGIIRSLGPSVKDVAGNLGQVDEWSHGVQTNYGDDLGNACRQSDDLIGAILDKENAGIGQMCFNQSSLVTWEDQIDSNYSLTDLLNWIDRNKHALGSIESTPNHSDHSSHTTTTDSTDAETLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC44</accession>
    <name>A0AAD8XC44_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_755767</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000108">
        <property type="protein sequence ID" value="KAK1717394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360881.1">
        <property type="nucleotide sequence ID" value="XM_060514664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC44"/>
    <dbReference type="GeneID" id="85398562"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="328"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="362"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="395"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="460"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="493"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="526"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="594"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="627"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="691"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1717394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="765" mass="83337" checksum="47C2BB8068663435" modified="2024-05-29" version="1">MDSPGRQSGTSLADLIRTSQLLTDRYSTVANSLNTAPVTLSDLAKECSAVTDALRRFKYLRETIPETLVFDPILLDQSCQDALDSINTDLSSLDFYSTRIRPATSDSAVDMSSGQITIIWNEDSLRQIQRQLKTNRQSLTFLLNCVPSEHVTSKNHSTFMHSSRLVSWDCAISPAVLNKGSRLRLSTIGPRPRPEAEITPVNDSFEVRSALKRLRPPPGILYKQSMRTTKDLHDAIDRGDEAAVVKLLLQRIDPNAPRFGSKLCPLRRALNRQIPSLVTFIAIAGADLESRGDEGDTILITAIKYGYSDKVVSLLCELGADVNAVDTLGCSAVHYAAMSAKYDDTLEVLIRAGGEVDRRDLGTRTPLIAAVQNYRFNAIEKLLEYGADLEARLQNGRTALHVAISMRSTPMTEFLSDQGAYLDRRVNEHTALTYAISTACPDIAEVLIGAGADINLPSSKGNFPLLAAASAGDLRTMKLLLSRGANFDAAGSEGYLPIHMAAHKNRVEVLQLLFKAGSRIDPTTEHGETPLTIAMHLGCFEAAQFLIEVGAEVDHSAPGAERIICQALKAGNTRIAIALIRGGADLTTPLLRNSSMTPLHLAAHYGQNDVLATMISTGVDLDTRTWPGFTPLFAAVRAGHLDTVRLLLAAGAYLRARSMSGANLMFFGTAHPAMIKLLMDLGLDVRERDHHGATPLHYAAVKGQYATVKLLLQHGARLVHASAVFESLQDYKTKAKYRQGTAAGLARQKGHLKLARLIEGWKFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCA9</accession>
    <name>A0AAD8XCA9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">MIP family channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_705085</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362017.1">
        <property type="nucleotide sequence ID" value="XM_060511502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCA9"/>
    <dbReference type="GeneID" id="85395400"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1721221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="364" mass="39619" checksum="B4F515C8E5F6D135" modified="2024-05-29" version="1">MSPASSIHDPGESQPLLSRHRRRTGTFQLPSFSGQRLVSPLSMRRASLQEVHPHHEDVEPVLPAAPVAAHQETRLHKPQWALSDRPPNTWAQIRHYWREEFAEFWGTFMILLFGAGVECETRLNYQSADIRENAGDFLQCRLAWAAGVAMAVWMSGGVSGGHCNPTVTVVLALFRGFPWRKVPSFLAAQVLGATFASLAVYLNYSTSIAEYEGGAARTLIGEHATAGLFFTFPKSGLPYAGAFYTEFLASAALVAIVFALADKNNLSPPKGTQPFAMFLALLAIGSALGINTGYAMNGARDTGPRIALAIVGYGSDVFTHDSYYWLWAPWAAAIVGGIAGACVYDGFIYTGRDSPFNIPRKEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDD3</accession>
    <name>A0AAD8XDD3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_80690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359710.1">
        <property type="nucleotide sequence ID" value="XM_060515934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDD3"/>
    <dbReference type="GeneID" id="85399832"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="39828" checksum="79D7985F9CBAA69C" modified="2024-05-29" version="1">MAEWTQFQDDEACSASDDSDADSVFDHPAFSFIEPDTDSSVGDTDEDTDEDTDEDTDEDTDEDTDEDTDIDNDVDTYVDPDVGPDVYPDVDPDDEPDGDFDEDSDDGEPDPVQMVLDAVIRHMRYWKFPSVTHGRFIISDIFSRFSSADFSVNTENEECSTVVGSLSPQTDEGGIRYEGYSYGDDPGVQPFHDHVSICVAGTTIPSHIFEELYRSVKAGVFVDVQIVEHVTLQPESLCPIQRSERTPEKHKSTVDRVKRMLFDAGFNIKHIRELSIPSGSRVAHEVETGDLYRDRHRYANRQGMYDELLAWQTAQIRTGGYIKLPLVRAYKRQKKRVRSDLGDGRALKRIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDY1</accession>
    <name>A0AAD8XDY1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_625644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363682.1">
        <property type="nucleotide sequence ID" value="XM_060508503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDY1"/>
    <dbReference type="GeneID" id="85392402"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52765" checksum="ED13B8785137DC4B" modified="2024-05-29" version="1">MTGKRRRSSESTPSAAHDVSLQNTIRRANRGLVNRPSEPGTHADAYYRNLYSTEPDFGKLGRQDPLFGAMLKRGNLDFNDPSAVMQLTKTLLKADFGLNIELPDDRLCPPVPNRHNYLLWLKTLLDSTTYGVPDQKVLGLDIGTGASCIYPLLGCTQRKWSFFATDIDSKSLQFAQRNVELNNLQSRISVIARVPQDPIMPLADLGIESLTFVMTNPPFYTSEDDLLNSAKQKSRPPLTACTGAPVEMVTDGGEVKFVSRILEESLFLRERVQWYTSMFGKQSSLEEFIAILKEKNINNYAVTEFVQGNKTRRWAVAWSFGTMRPSEEAARGMKAAVWKKLLPPSVESEVTTFPLGTEIGKLQDKIQELMSLLELVSWEWNREKLVGIGRAQENVWSRAWRRKKMREEREGKTVVEGSANPEVCKFGFEIAMDVGREGIVLRCRWREGHDQALFDSFGGFLKTRVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE18</accession>
    <name>A0AAD8XE18_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AttH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_384376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363817.1">
        <property type="nucleotide sequence ID" value="XM_060502733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE18"/>
    <dbReference type="GeneID" id="85386632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.370.10">
        <property type="entry name" value="AttH-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023374">
        <property type="entry name" value="AttH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010791">
        <property type="entry name" value="AttH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053112">
        <property type="entry name" value="Fungal_Dehydratase/Hydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40617:SF1">
        <property type="entry name" value="ATTH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40617">
        <property type="entry name" value="TERPENE CYCLASE ASQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07143">
        <property type="entry name" value="CrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17186">
        <property type="entry name" value="Lipocalin_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042297506" description="AttH domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="AttH" evidence="2">
        <location>
            <begin position="111"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="343" mass="37421" checksum="865673BC2EA0EE10" modified="2024-05-29" version="1">MRRLSRGCWALLVGATSAVRFDIVPDTTGIDSLGSSLPTLYSFQESQLASEQSNSYWAASFVTASNDRQYAIMSQQMPTGTGQSIFQSSILDLEDTSNYWLTAGLAPLQGNQTIKNGLLDIAVDGSAFKSPSSDSFSSLNTWGEYDTYAFNLTFDASSPVILNGGVGRFRWGTGTTTQWSLPSCKTQGSFTINGTTLEVDPTRSLTWYDRQHGVGGPNNFTWFGLNFPGGIRASIWYSNTAEPSQKLRFATIRAEDGLHIVRFKMAPGNATTWTSPVTNTTYSQDWKLFFDNGDSLAIKSIRQDQEKGSGAGRFYSGVVEAEGSLFGQEKGFGFVDIVPKLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE36</accession>
    <name>A0AAD8XE36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mo25-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363877.1">
        <property type="nucleotide sequence ID" value="XM_060514324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE36"/>
    <dbReference type="GeneID" id="85398222"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000257">
        <property type="entry name" value="Conidiophore development protein hymA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="376" mass="43266" checksum="E7448EA0D8597A96" modified="2024-05-29" version="1">MSFLFGRARTRPAVDLPKQARDHVTKLEGPNGAAKAEELAKVLNQMKFILQGTHESDSSPEQIYQLVTGLIEEDLLYLLAVNLWRLPFESRKDTQVIFSYVFRFRPPTASPKSDPLALSYVVNNRPQVLLELCRGYEHKESATPAGSVLREVLKSEAAAAIILYDDNEESGSSNKGINLIDRDRRQSGEGVFWRFFDWVDKSSFEVAADAFTTFRELLTKHKELVPRYLSVNFDLFFDKYNNILVQSNSYVTKRQSIKLLGEILLDRSNYSVMTAYVDRGEHLKICMNLLRDDRKMVQYEGFHVFKVFVANPHKSIAVQKILLMNREKLLTFLSHFLEDRTDDEQFIDEREFLIKQIRNMPPNPVPPQRHGMPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE78</accession>
    <name>A0AAD8XE78_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_755188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361538.1">
        <property type="nucleotide sequence ID" value="XM_060514579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE78"/>
    <dbReference type="GeneID" id="85398477"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1719454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="58132" checksum="577579E1D2BD4984" modified="2024-05-29" version="1">MGNQKRPTSKGFAFVITDTSGKPKTDDRKLIRSHVMRGKNTRPSRGGQKRSTKWVNQTSPQPPQEPEEPPAPKSLTALVKEPRKQKLYKIAWYEHVFRTPNDLYMFQFADDIDAASRGMLFEFYAVVKETMYPIEWCLQYDESKTPWFYWLLTDAAFLHSILFTVGLMNDTVKGDNPSKHTNFHIWKTLQLLNQNIADQDMALADSTIATIVSMCMVAEIFGQRDNAAAHIQGMRQIVKLRGGIESFSHNLQLQVKICRYVSFLDIYAQHLTKQRVDIGWSLCTGEKPLYFRDTFSWEPAFSPILGKVPVGSEICPGSSSVRLLLDAADSRLGNVFQDLHDFSRLATALYHTNRKIDPNLFQEFMTCVQYRLLYSETTAHNALAELGRLGMISYITTLFLQVQGAKFQFTSLTTKLRSACKKFEISASTCASTKLLLAWSLVIGAISVFEEEDDRWLLPKLANLRDSLGPTWPEAKAKLENVIWTENVHDSAGIKVFEKLVLHVARIPRASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XED6</accession>
    <name>A0AAD8XED6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_587412</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000115">
        <property type="protein sequence ID" value="KAK1716186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360580.1">
        <property type="nucleotide sequence ID" value="XM_060506035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XED6"/>
    <dbReference type="GeneID" id="85389934"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1716186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="430" mass="47568" checksum="5C5D5D8BB1F64B39" modified="2024-05-29" version="1">MAIKNFSGPSPLKVAIIGGGPGGLGAAIEFGKLNYVDWSLYEKKSRISETGGGISLQRHTWRLLELNGAAKNIDPLDFFRSPDGTSGQSRNGRTGKLLEQHHHPKDTPPQQVSCRMVRAKLQAALLKEVDQSRIKTSKKLVDITKLPTGRIAIRFEDGFSDEVDLLVGADGIRSFVRSYAFPEHKIKYNGQSAYRTIIHKPTAEKVEGIPKSPVFWQNTGGKYVFTCPLGGDDFEVTARIRRPIEGQEHVSWGRPFDFATIASEYDEFCEPVRKVIQLAAQGETQEFALFSGPRLKSVVHEQAIALIGDASHPLSGAFGAGAGFALEDVYALTQSIDWHWSNGGDLSAALELYDQIRSPHYRDLYKVLDDFGAMNTTLLSENIPVNEEIEERVRRAAESKSTWMYHYEIDKAVEKLLGAANQHGQVAAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFC9</accession>
    <name>A0AAD8XFC9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_628361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362813.1">
        <property type="nucleotide sequence ID" value="XM_060508699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFC9"/>
    <dbReference type="GeneID" id="85392598"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="59" mass="6640" checksum="2C763D79E216A60D" modified="2024-05-29" version="1">MNVDFTKAIDAMRLAICVESLSATCQQLSASTKIQQYQGIEIEYTQEQQNYCCCCCCCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFE5</accession>
    <name>A0AAD8XFE5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_777440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365347.1">
        <property type="nucleotide sequence ID" value="XM_060515480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFE5"/>
    <dbReference type="GeneID" id="85399378"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="222" mass="25002" checksum="0618BA328332DFDC" modified="2024-05-29" version="1">MRKLLIGTTGYAQKKLSWLAKSSTKADVTVQFASQLASSKRDKTSSGLVNMLQAPRSNGKSGLFSRFGEASRGKRYQLFRAAAFLSLGMQATVIYGQVTSDVYKWMKGDILVGLFLIHNSAWVLCTNNAQVDYYHNEVVFDACPQNHPTQISVSCNNRKTWQKKWLKKVAQGAVILYATFNSICIWEAWITLAVFFTGASKKTESGWNWARHLPLPLSYRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFX5</accession>
    <name>A0AAD8XFX5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">precorrin-2 dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_581096</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>precorrin-2 + NAD(+) = sirohydrochlorin + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.76" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363368.1">
        <property type="nucleotide sequence ID" value="XM_060505425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFX5"/>
    <dbReference type="GeneID" id="85389324"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.110">
        <property type="entry name" value="Siroheme synthase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3280.10">
        <property type="entry name" value="Siroheme synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028161">
        <property type="entry name" value="Met8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028162">
        <property type="entry name" value="Met8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35330:SF1">
        <property type="entry name" value="SIROHEME BIOSYNTHESIS PROTEIN MET8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13241">
        <property type="entry name" value="NAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14823">
        <property type="entry name" value="Sirohm_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75615">
        <property type="entry name" value="Siroheme synthase middle domains-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Siroheme synthase central" evidence="8">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Siroheme biosynthesis protein Met8 C-terminal" evidence="7">
        <location>
            <begin position="165"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="262" mass="28416" checksum="C4DBFFD2452A282B" modified="2024-05-29" version="1">MAAKSTTKKFPEVKGGGSLILAWQIKGKKVLVVGGGEVAAGRILNCLDADANVTVVCPASGLNPEVAHRVEQAQVTHVDRLFEPSDLDGAAMVLVAIDDPAASTVIWKLCKERKVPANIADVPPECDFYFGSVHRDGPLQIMVSTNGKGPRLAAIIRRHIAKSLPKNAGNAIEAIGTLRAKLRKIAPNSEESPKRMGWMIKVSNKFDWEEICDLTDEDMENLLRFYATNEVPTIDDLLAMRENPGFNKMDVFDGSFGFSVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGM2</accession>
    <name>A0AAD8XGM2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Immunoglobulin I-set domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_750872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366562.1">
        <property type="nucleotide sequence ID" value="XM_060513977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGM2"/>
    <dbReference type="GeneID" id="85397875"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.520">
        <property type="entry name" value="Glycosyl hydrolase family 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031924">
        <property type="entry name" value="GH115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042301">
        <property type="entry name" value="GH115_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842:SF2">
        <property type="entry name" value="GYLCOSYL HYDROLASE 115 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15979">
        <property type="entry name" value="Glyco_hydro_115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085897" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="domain" description="Gylcosyl hydrolase 115 C-terminal" evidence="3">
        <location>
            <begin position="856"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1078" mass="119410" checksum="131CFC00FAB4F975" modified="2024-05-29" version="1">MAFVNLRSISLVVLSSLAPLILALGQQPIVSFESASGSFQIAGGDVGTGQILVSDDDYWGVIRAAGDLALDFGRVTGTNYTLSNGGNSSKPALYTFAPVDVTNNTVYRVLDEQSFSGPNYTNPAPDHTVVIVGTIGHSKVIDSLVKAQKLNTSEVEGQWESFVSQLIDEPIPGCSRALVIAGSDPRGTIYGIYDVSEQIGVSPWYFWADVPSKKATEIYVLPERKVQGSPAVKYRGFFINDEQPGLSSWVSTKWNDTWNDAAGYNYHFYSLVSELLLRLRANYLWPTLWGSMVYVDDPLNQPLLDAYEVVLGGSHTEPLMRAQNEFRTFYQGQWAYNLNNKTIDDYFRYGVQRAKPYARNSLWTMAMRGTGDTAIEGNLGVEGIVKMLEQLVANQRAIIEGGLEIDSASEVPSLWCLYKEVQSYQEKGLVVPEDITLLWADDNWGNVRRLPLVNETDRSGGAGVYYHFDYVGDPRDYKWINTIQLEKTAEQMSLAYARNARRIWIVNVGDLKPLEIPTSHFFDLAYDTEKWGVDGTGKWLEAWATREFGGDHAGNITDILTRYGMYAARRKYELVEPNTYSVINYNEADAVLGQWATLREEAQAVYDALSEEYQASFFEMILHPISAGEILHKIQINGAKNQLFAGQKRNLANDIIDESRTLLDADAELTIRWDELLDGKWQHMLDQTHLGYDGYWQQPMRNTLPDMRYVQTAFPSLGGQIGVGVEGSNASVQGDDKWHTNSANDLAVPPLDPYGAISRYFEVFTRGNTACPWTASPWQPWVKLSQYNGTVGGNNGTDSRVYISIDWENAPAAPNTTQVYINVTTPCKGKEKYAGSGQRVIVPVVNRAVPSNFTKGFVESDGHVSIEGPHYQNIIEPSNSTRISNSSSKLEYHLFENYGRTLGGVGLYPPESEKVKLDEGPALEYQMYLFTNTSKANVTLYISSTSNYLGDGNPLEYGISLYPTGGSAPQPKTVQPVGKTQGQNMPDGWGYAVGDAVWGLTGNYTTTAFNVTQEGAYTLRVWALLPNIIVQKVVVDLGGVRKSYLGPPESLLLGRDEQGAVKRTAFTETPGIVGGRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHC8</accession>
    <name>A0AAD8XHC8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">GTPase CDC42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_649651</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367357.1">
        <property type="nucleotide sequence ID" value="XM_060510298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHC8"/>
    <dbReference type="GeneID" id="85394197"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01874">
        <property type="entry name" value="Cdc42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000236">
        <property type="entry name" value="Cell division control protein 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037874">
        <property type="entry name" value="Cdc42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1727302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="21593" checksum="982A25F4AD4E8CA4" modified="2024-05-29" version="1">MVVATIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVREKWFPEVHHHCPGVPCLIVGTQVDLREDPSVREKLSKQKMSPVRKEDGERMAKDLGAVKYVECSALTQYKLKDVFDEAIVAALEPPAPKKKSHKCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHH1</accession>
    <name>A0AAD8XHH1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_750852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366536.1">
        <property type="nucleotide sequence ID" value="XM_060513972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHH1"/>
    <dbReference type="GeneID" id="85397870"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="313" mass="34717" checksum="F2B963B2BBAD5F6A" modified="2024-05-29" version="1">MASIVAIAGGTGDLGRTIVEAILADRKFSVVILSREANDDREKEIGARILPVDYSSADDIARVLEENNVHTVISTLNNMASVEPELNLIAAADQAAATKRYVPSIWGAKFSREYAEEMPIIKPKILIIDALEKTSLEFSAWYTGYFADYYVCPPLKSHIKNMAMVVDVVNNKAGIPGSGDVPVAMTFTADLAKFVAAALTLPKWEQEVYLVGDRLAWNQLVELAEAVKGVKFDVTYDTIETLRTGTVTKLPRHRSPYPYISDEQLQPMFATLGLMFERGVFDVKAETSITRNFPDLKLRSMKELLEEAYKLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHQ3</accession>
    <name>A0AAD8XHQ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_777944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000045">
        <property type="protein sequence ID" value="KAK1725113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365168.1">
        <property type="nucleotide sequence ID" value="XM_060515493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHQ3"/>
    <dbReference type="GeneID" id="85399391"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALNH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042142578" evidence="7">
        <location>
            <begin position="16"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="542" mass="61128" checksum="8BA420DA0DBC8535" modified="2024-05-29" version="1">MVSLFLIPLAIVAFAIFKLRNVGRRPKNYPPGPPTLPLIGNLHQIPPTQSHHQFKQWAKEYGPVYSLILGTKVMIVLSSDRAVKDLLDKRSNIYSSRTDLYLGNIVSGNLRVVMMQYGETWRMIRKIFHQVLHINAAKGYVPYQDLESKQMLSGFLEEPDSFVDHIRRFTTSLTTQMVFGFRTTSIHDEKLKRLYHCVEKWSEVVGSSTAALLDVYPPLRNLGFMSPGKRYAAALHKEERALYVGHWMDAKDRVLEGTAKSQPCFCVGIVESQKTLGFSDALAGYISGSALEAGSDTTASTLTGFVQAMVLHPSVQKQAQEELDRVCGTERLPNMDDWDSMPYIRACVKESLRWMPTAILGLPHAVIQDDEYMGYKIPKGAGVMLNVWAINMDENRFENPRAFDPSRYEGDEQNSFESAMNGDPSKRDHYVFGAGRRLCQGTHIADRSLFLSISRLLWAFNLEKAVDAEGNEITPNAENLTDGFLVQPKPFPAKIAPRSDAHVQVIRREWKASQALLDKSKQWKEIPSGMVFESLVSSDFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHR9</accession>
    <name>A0AAD8XHR9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_573645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366866.1">
        <property type="nucleotide sequence ID" value="XM_060504632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHR9"/>
    <dbReference type="GeneID" id="85388531"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="424" mass="48118" checksum="C322EF68411CC4D6" modified="2024-05-29" version="1">MLAYGASKVLKALWFGFTGPLAKIPGPRLNRFTALPWMAAVVRGKAFEQGINYNRKYGDIVRVAPDLVLVSDEKSVHQILVEMDLRKSVLYEKFSQNEDGVTLFTMRDRAQYRTRRRLFSHGFSISYLKGLEPLKLSCIEALEEFIDKQCTQDGGETVIDAWNLMGRLASDIMSATAFGGSFELVKNGEHPIRKKFSESFKRGTIYQLLPFLKYIPFLPKFRDPELAQLISDIIEKRQASTDKLAKPDLLQLLLDTHEKNPETLSRIEVFSEMLVFWLAGSETTASTLTFAMMFLLNDPPSYQRLVNEIRTRFPLSDSPVSDDQTTDLPFLHAVLKETMRLAPPATGGLQRQTDEDVILSDHLIPAGTRVTANTTVLHWDEKQWPDAEKFVPERWLSDYKGMAASERTAYYPFSAGSRNCIGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHS6</accession>
    <name>A0AAD8XHS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CAP20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_753186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363865.1">
        <property type="nucleotide sequence ID" value="XM_060514321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHS6"/>
    <dbReference type="GeneID" id="85398219"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="19910" checksum="68FFF91913D8BC10" modified="2024-05-29" version="1">MAQVNGDLPSVPSAALQHFLDYPVVHDGVVTFRNHPVGKKSLVYSDSAYKTFAEPLLPYFARPWGYLRPYAEKADNLGDQALTKVDERFPVVKKPTEELYAGAKGIIALPIRTGVEAKDHVLKTFSQQKKKVGSENVVAYGKALIGTALITTSELIIWVGDVIHYKKEEAKDVVNEKVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHW0</accession>
    <name>A0AAD8XHW0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_576844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365348.1">
        <property type="nucleotide sequence ID" value="XM_060504958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHW0"/>
    <dbReference type="GeneID" id="85388857"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000247">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000106">
        <property type="entry name" value="MFS transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF14">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="555" mass="63295" checksum="82E0AA241C4F2088" modified="2024-05-29" version="1">MASKGVEGPFRDSTKEVNTIQTQAATDTSASSLKEQVAQQYGSTDEHVFSDPSIADHWRKVYEKASYENRHRFDPNYTWSAEDEKKLVRKIDRKIMVWAWVMFCALDLHRRNINRAISDNMLPELGMTTNDFNYGQTIFLLSFLAAELPSGLVSKKLGADVWIPSIMIGWSITAGCQAFLSNRAGFYAVKALLGLLMGGFIPDIVLWLTYFYKSNELPLRLAWFWTALSTVNIVGSLVAAGVLQMRGVAGWAGWRWLFLIEGIVTLIIGLFSWGLMPPGPTQTRNWFRGKDGWFTEHEELIMVNRLLRDDPSKGDMHNREAVGPSLLFKAIKDWEQWPLYLIGLTTYIPPSPPSTYLSYILRRLGFSTFQANLLAIPSQFLFAVNLLIISWVSGKFKERAIVSSISNIWIFPWLVALVALPADTSTWIRYALLTGLLSYPYCHAILVGWNAKNSNAVRTRAVSAALYNMFVQAGNIAASNIYRDDDQPLYRRGNKILLGVCCFNIVLFYIVKAFYIWRNKVRDRRWNAMSKEQQEDYSLNTTDEGQQRLDFRFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI73</accession>
    <name>A0AAD8XI73_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH:ubiquinone oxidoreductase 17.8kD subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_719032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365738.1">
        <property type="nucleotide sequence ID" value="XM_060512136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI73"/>
    <dbReference type="GeneID" id="85396034"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034444">
        <property type="entry name" value="Nuo17.8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42100:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 178 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="172" mass="19561" checksum="00B67D3DCE21FEA2" modified="2024-05-29" version="1">MQAIRTRAVCIARQSRLTGLRQSRTYASGGDHGHHHAHTVEEPIGNFFWAVVAIIPSAYAVYKITAPGKEGEPPYLTQKIHEAWHWQETWKERNALHTKAVEQAGFDRLLFFSTPANRDVDLRFPEAVSNFAARNVIAGSQTNLDHVIAHYKKQHLDEEERKAKKLAAQKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIG1</accession>
    <name>A0AAD8XIG1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_575336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366083.1">
        <property type="nucleotide sequence ID" value="XM_060504801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIG1"/>
    <dbReference type="GeneID" id="85388700"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017171">
        <property type="term" value="F:serine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46331:SF2">
        <property type="entry name" value="VALACYCLOVIR HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042144995" evidence="1">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="67"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="290" mass="30732" checksum="F601AC442156F0F2" modified="2024-05-29" version="1">MHFNNALMAAVAVAGSVSGLAVRQTPIWQTLPATPNLPTPISTAKTAINGIQMWFQEYNKAAGGVPIVMDHGGLGYSAYFGSVISRLVSAGHYVIAVDRRGHGRTTYNKNDVFTYDQMALDIHDLLAGAGVSSYNVVGWSDGGITTLAALINSVTAKPINKAFIFGASAKPDQTNATFSDTAIFSTLVARCRTEYGTLQPGANFTEFATKVATMEGTLPQFTDAQLKSIPGAKVMIAGAEHEEAVNRDVPGILNKAIPGSKVTILTGVSHFAPMQDPDQFTKAVTDFFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJD4</accession>
    <name>A0AAD8XJD4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_668510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ustYa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366340.1">
        <property type="nucleotide sequence ID" value="XM_060511106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJD4"/>
    <dbReference type="GeneID" id="85395005"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="231" mass="26435" checksum="56169C17F2E625FE" modified="2024-05-29" version="1">MSSTPEYQPFLKYSDDPRTEEPTSPSRPSTRRNTLFSHILVLIGTSLVWILVFFLFFPTPAATTASQDAALSQSSASYGAGQRHNITTGRKRISCGNTTKEARAKGCRYDVLLNHWVPAQCFDKDSVDEYQEDASWGAFADKNMTQQLTIDEMSERDFYWTSIRDHINHCAIMWRRQFYALYDERAAIDTIVTSPGHTEHCSQYLMDAVDSKWKEPTKTMRGFAGCWVRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJG7</accession>
    <name>A0AAD8XJG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alcohol dehydrogenase GroES-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_574362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366580.1">
        <property type="nucleotide sequence ID" value="XM_060504708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJG7"/>
    <dbReference type="GeneID" id="85388607"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08296">
        <property type="entry name" value="CAD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000039">
        <property type="entry name" value="Alcohol dehydrogenase AdhP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF7">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="8">
        <location>
            <begin position="17"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="340" mass="35597" checksum="808F0810C1C35678" modified="2024-05-29" version="1">MSGLPKTFKAAVIESKSAPLKIVDQELKQPGPGLVLVKVLACGVCHSDVGMAEGGFGDVFPRIPGHEIIGDVVAVGEGVSRFSGGERVGGAWHGGHDGTCRQCQKGFFQACDNETINGVFRDGGYAEYVLLRAESAVRVPKDVDPAEAAPLLCAGVTVFNSIRKMQIEQGNLVAIQGLGGLGHLGVQYASRMGYKVVVLSSGSTKKDFAMKLGAHEYIDSSATDPVKELKKLGGAALILATAPNPKIISPLTGGLQPGGKLCVLAPVGGLEVDTIDLIVGGKSVCGWPSGHQMDSEEAIDFAATHGIKCMVERFSLDDAKKASEHMISNKVRFRSVLVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJZ1</accession>
    <name>A0AAD8XJZ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Family 92 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_126510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368455.1">
        <property type="nucleotide sequence ID" value="XM_060501188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJZ1"/>
    <dbReference type="GeneID" id="85385087"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1610.10:FF:000002">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.10:FF:000010">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2080.10:FF:000001">
        <property type="entry name" value="Alpha-1,2-mannosidase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.60:FF:000002">
        <property type="entry name" value="Glycosyl hydrolase family 92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF23">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227578" evidence="2">
        <location>
            <begin position="19"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="4">
        <location>
            <begin position="24"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="3">
        <location>
            <begin position="273"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1728400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="775" mass="85209" checksum="1553D5A4B7DD2E7B" modified="2024-05-29" version="1">MRFLASLIAFVEAGYCQSFDPLAFVDPLIGSQRGGNVFAGATLPYGLAKAVADVDGEKTGGYSTDGSNITGFSIVHDSGTGGNPSLGNFPLFPQICPGDELNNCRFRIGDRATQHDVNKTIAEPGYFSVELASGVKADMTVSEHAALMRFKFPSGGNEHPLVLLDLTDLWASRQNASIKVDTPTGRMFGNGTFLPSFGAGSYELHYCVDFFGAKVFDTGVWVNNRAGNEPKELFITRGFNLFYLEGGGFVRFKELANDTITARVGVSFKSSDQACRNAEKEIPDPLNNFDTLVKTAKDAWREKLSPISVKAAGATEDLQKSFWSGLYRNMISPQNYTGENPHWDSGIPYFDSFYCMWDSFRAQHPLLTVIDPAAQAQMVNSMLDIYKHEGWLPDCRMSLCKGWTQGGSNADVVIVDSYVKNLTSIDWKVALAAITKDAEDEPLEWSYEGRGGLTSWKTLNYIPYLDFDPIGFGTNSRSVTRTLEYSYNDYCLATLAQGLGEGQLHDKYISRSMNWQNLWKADQKSLINGTDTGFSGFFQPKYMNGTWGFQDPIACSNLAGFCSLTTNPSETFEASIWQYQFIVSHSTSTLIDFMGGDDAFVSRLSYFHASPLADISNEPVFLTVYLYHYAGRPGLSAERIHKYIPSAFNSSRGGLPGNDDSGAMGAFLAFSVMGLFPVAGQNVYLITPPFFEEVSVKSPVTGKSATIKCVGFDAAYKNIYVQSAKLDGEAYTKSWIGHEFFSQGKTLELTLGDKESDWGKSKEARPPSYVAVSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL21</accession>
    <name>A0AAD8XL21_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone-like transcription factor and archaeal histone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_51084</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369401.1">
        <property type="nucleotide sequence ID" value="XM_060503301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL21"/>
    <dbReference type="GeneID" id="85387200"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="9">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="134"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="21928" checksum="60169BE3FC42495C" modified="2024-05-29" version="1">MSDSPQSPPKDVDQGVQSPEEEQMNEAQDPQSGGLTYEFEVKEQDRWLPIANVARIMKNALPENAKIAKEAKECMQECVSEFISFITSEASEKCHQEKRKTVNGEDILFAMTSLGFENYAEALKIYLSKYREQSQSNRGETSHRPGSSGYGANPPTGAGSFQAEPQNSVLGGQQGDGTADAQGYMYGAQTAHNGTGGADGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLU7</accession>
    <name>A0AAD8XLU7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_604986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369855.1">
        <property type="nucleotide sequence ID" value="XM_060507305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLU7"/>
    <dbReference type="GeneID" id="85391204"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="118" mass="13615" checksum="30A6D700095B0338" modified="2024-05-29" version="1">MRGCCISLARPLGTRNRIVCVGVSLRSGQNHPLRQLSSLHGFRIYRRKLQKYHHKDSLQVIESYDRSHAHQRESCELGSGYILALQTMDRIGYRGFLVTEPIHIRPSFSARCFYGIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM45</accession>
    <name>A0AAD8XM45_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369956.1">
        <property type="nucleotide sequence ID" value="XM_060513529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM45"/>
    <dbReference type="GeneID" id="85397427"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000221">
        <property type="entry name" value="Methyltransferase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="6">
        <location>
            <begin position="151"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="349" mass="40327" checksum="3DFC886A3E967DF0" modified="2024-05-29" version="1">MTSLASENTGADEQVLVEKAAELQISEPATGEEPAAHRSHDPQFNQKRSDPFQFGSRLLGEQDDVFEFNAWDHVETDEVYKEYSEQQYEMQRQSPVSDFDKNRLNNNPARMWDLFYKNNTANFFKNRKWLQQEFPILSEVTKEDAGKKTILEIGAGAGNTAFPILATNKNPNLRVHACDYSKQAVEVMRTHESYNQDHMQADVWDVTSEELPPGLEEGSVDVAILIFIFSALAPNQWNQAVANVHHLLKPGGQVCFRDYGRGDLAQVRFKKGRYLDENFYVRGDGTRVYFFEKEELERIWSGKTQEVSDNDAKVEFNVDDLGVDRRMLVNRARKLKMYRCWMQGRFTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMA4</accession>
    <name>A0AAD8XMA4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_422079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370107.1">
        <property type="nucleotide sequence ID" value="XM_060502986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMA4"/>
    <dbReference type="GeneID" id="85386885"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF3">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="70510" checksum="F43E51477F196A53" modified="2024-05-29" version="1">MAGYPGQRPYGGGPPAPRPGPGPGPAPAQRGPPQQYDNFQQDGYGYDYYDDGGYDQNYGGQYQDPNYGRGPPPNQGYPPQGMYPPNPMPPPPQQQQQQLPPPQNAGYGGPGEFGGDQDGYRDTRASFGDVYDAYYQPSRMSNQSAHSYGHHDAPEYNGAPSHAPRGSFEQHMRPGIAEHTQPGAKRVPEMSRTKSQPDLRQSQQAVFEMAGDAPPMPPMGNGYQDAYNQPNGWDQPQNPQMGRPGLPQGPSPNRGPDSLPSHPAPVRPGHMPNSMVVKSTPNDQETAMRLAKRLVEAADVLAPNLADPKMKTRARERYLADANKILKKLSSAQNSEAMFFYADCLGRGLFGLEPDNKEAFTLYQSAAKLGHAAAAYRTAVCCEIGHEEGGGTRKDPLKAIQWYKRAATLGDTPAMYKVGMILLKGLLGQPKNPREAVGWLKRAAERADAENPHALHELGLLYESAAPNDAIIKDEAYAFQLFREAADLGYKFSQYRLGCAFEYGLMGCPVDPRQSIMWYSRAAQQGEHQSELSLSGWYLTGTDNVLQQSDTEAYLWARKAATAGLAKAEYAMGYFTEVGIGVPANMEDAKRWYWRAAAQDFPKARERLEDLKRAGKNGPRQRERISRSKIGKQQEGECSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMF6</accession>
    <name>A0AAD8XMF6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GDP/GTP exchange factor Sec2p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_424732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370200.1">
        <property type="nucleotide sequence ID" value="XM_060503003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMF6"/>
    <dbReference type="GeneID" id="85386902"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="126"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="12"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="367"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="575"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="126"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="691" mass="75467" checksum="A78A94AC48B016C6" modified="2024-05-29" version="1">MDSFIAVAGWAQHTSPQPGGRPFGHFRSLSSIARSPSPSPRATKTSSQAPSVVDMPIMSSSVASSPTLRPTTTVTPPDDDGELSTLPDPRSRAMSPASEADAAQHPELNDEVATLSAKLINAINHQTTLDDTLSATRQELERAREKIKHLEEQNESQREMLAGDIWIRRKTAEEEKKTIMLRVNQEKKLREDAEKEQKRIEQELESLSTALFEEANNMVITAKEEARVEQEAIQRKNDNLRSQLGDMEALLTSQQQQLADLKHVMEQMMLERDDATTGTAPSSPGFSKPDTTKDDDRSEGLVASPLLDPSSPTYPTSLTHLIQPVLRTDLGAYEDFLSLTKLSRNRAGSRVSSGSYNGLSGLGLGMGGSTSSAHPSNASTASLSTAGTPATSSPQTPNTPASVSSTASANVGPPPPALKETKFFKRVLAEDVEPTLRLDIAPGLSWLARRSVLNAMSDGSIVVEPIPANAPFASIVKPQFYPCSLCGDARKDEEHLRTYRFRTSESESAQRYPLCKYCLGRVRSTCDFLNFLRIVKDGHWRAEDEDAEKAAWEESVRLREQMFWSRIGGGVVPASHHHSLPLEKSPRTSHESESREIEPEVAVTPSENINDDATPFATPLEETASQLDAEESLARPETPCPSNRNSTLSSSPEKGSIAEKDGEKRLSINIPIKEEQQIIVATTEEKAEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMV0</accession>
    <name>A0AAD8XMV0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_566880</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370345.1">
        <property type="nucleotide sequence ID" value="XM_060503896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMV0"/>
    <dbReference type="GeneID" id="85387795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000411">
        <property type="entry name" value="Probable Ste20-like kinase Don3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF27">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="10"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="341"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="539"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1730290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="625" mass="69309" checksum="9B32A40E27AC0C48" modified="2024-05-29" version="1">MADEGVAEHYQVLEELGRGSFGVVYKAIEKATGETVAIKHIDLESSEDDIQEIQGEIAVLSTCASSFVTQYKGSFLRGHKLWIVMEYLGGGSCLDLLKPANFAEVHIAIICRELLRGLEYLHAEGKIHRDIKAANVLLSEAGKVKLADFGVAAQLTNIKSQRNTFVGTPFWMAPEVIQQDGYGFKADIWSLGITAMEMANGEPPLAHIHPMKVLFHIPKNPPPRLENNFSKDFRDFVAQCLVKDSDRRPSAKDLLRHRFIRSAGKVEALQELIARKQMWDANQNRRSHPTFYQETLHTMSSRDDTDEWVFDTVKSVAPKRPNGHARKPSYFAAEEAMRRLDPKDAPLGPSSPAPGTVRRSTVRRQPSSRQSSGTQIQTNGSPRSTVARRPLQPDMSYGNSGSSVRLFRRVPSDGSVTAWEDTSPEGTMGNENKAPMRAAAIDTNSKEALLGRRLFNRVLDPTLAELHAQTSGMQRREALAKLTDAFALLDSVDPEGAYHLMQNMMTAVSQDPKLNQALMPQQSVKIPSDGTPQGTVIIRSAAPTPSSSPTKLMMAPNNPHLKSHRRRNGSIATPESAEKERSEKTAVEAKYPGRPPRPGMEHCKQLSDVLYGRWTEGLRIRWPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XN93</accession>
    <name>A0AAD8XN93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370477.1">
        <property type="nucleotide sequence ID" value="XM_060513470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XN93"/>
    <dbReference type="GeneID" id="85397368"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042053646" evidence="3">
        <location>
            <begin position="26"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="41817" checksum="B2B30A48C08626A3" modified="2024-05-29" version="1">MASLRNWRRLCIITWLLYTEIFVSGLQITPLSLPTSNPHNINNQLTPRSTLRADASCPVKGYTACGNGMADYFCCPSETTCIVLAEKTTALCCPKGSSCETISPITCDVTLQDVVENPTSPIHTTRRKESLPQCGSKCCPFGYTCRGGSACVLDDGQEEERPQTSSTPVSSTKTRTRTVSSAIPTTFTQAATTTTAVETVPAASSTPSPTPGEDLPTPSAVTSPSETTPAAAAAASPRSSTSGGIIAGTTVAAIASVAGITCLLWFKRRSISESVGSAKFPRPWQQLRQNGSDQDVSSLPRYNSPPPAYAVEMKSPLAKPYTWKHYSPDSFGRDRYGGRDDDGSVPVPVSVALALAVELPATPVSFSQWHVREEGEATRPRSHYEPYRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP06</accession>
    <name>A0AAD8XP06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_289722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370988.1">
        <property type="nucleotide sequence ID" value="XM_060502180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP06"/>
    <dbReference type="GeneID" id="85386079"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="177" mass="19155" checksum="DA7C3D564A8B58F4" modified="2024-05-29" version="1">MSSSDGSLGSTGSSYSLSNMPYTWILTPLIVFLALGIIATLVQFQRRRRLRKLGLQRPWPRRDLEANRQRGQRSSRNGRWAWTTRSDEGLDEFGEAPPAYEPKAKPGQAYAREGSFEMAHHVEHTARGAMPPPPPIGGTAGVGRGSLPPDYGTATGSTSSSTPPPAVTSPPTAMTRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPA2</accession>
    <name>A0AAD8XPA2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome b5-like Heme/Steroid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_599274</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1730947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371002.1">
        <property type="nucleotide sequence ID" value="XM_060506983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPA2"/>
    <dbReference type="GeneID" id="85390882"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF14">
        <property type="entry name" value="CYTOCHROME B5 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="83" mass="9488" checksum="8F4E8D7EAD6BC7B3" modified="2024-05-29" version="1">MSKTFTTQEVAQHKTEKDMWLIVENGVYDITAFQSEHPGGEKILKRFAGKNATKVFWKYHNEKVLEKYGGKLKIGEVAESAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPW5</accession>
    <name>A0AAD8XPW5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Multifunctional tryptophan biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Anthranilate synthase component 2</fullName>
                <shortName evidence="16">AS</shortName>
                <ecNumber evidence="16">4.1.3.27</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">Anthranilate synthase, glutamine amidotransferase component</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="16">IGPS</shortName>
                <ecNumber evidence="16">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="16">PRAI</shortName>
                <ecNumber evidence="16">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_564905</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="16"/>
    <dbReference type="EC" id="4.1.1.48" evidence="16"/>
    <dbReference type="EC" id="5.3.1.24" evidence="16"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371425.1">
        <property type="nucleotide sequence ID" value="XM_060503693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPW5"/>
    <dbReference type="GeneID" id="85387592"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000136">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000031">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016302">
        <property type="entry name" value="Anthranilate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001377">
        <property type="entry name" value="PRK00278.2-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001382">
        <property type="entry name" value="TrpG-trpC-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="18">
        <location>
            <begin position="28"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="19">
        <location>
            <begin position="255"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="20">
        <location>
            <begin position="589"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR001382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1731370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="765" mass="82966" checksum="9D1BE3D2E9286685" modified="2024-05-29" version="1">MPSLDIVDHSPQHPDPSPPIPTASNLILIDNYDSFTWNVYQYLILEGANVTVFRNDKITLAELIDKKPTQLIISPGPGHPTTDSGVSRDAIKHFSGKIPIFGVCMGQQCIFDVYGGEVGSAGEWLHGKTSPLTHDAKGVYAGLRQGLPVTRYHSLAGTRVTLPDCLEVTSWVATEDGSPGIIQGVRHKEYTIEGVQFHPESILTAEGRTMLRNFLQLQGGTWEENSRLQKGSATNGAAAKTTSSAPAASKKNNILQQIYAHRKAAVAAQKLIPSQRPADLQAAYDLNAAPPQVSFIERLRQTPFDVSLMAEIKRASPSKGIFDININAPTQAKKYALAGASVISVLTEPEWFKGSIEDLRAVRQVLDGMPNRPAILRKEFIFEEYQILEARLAGADTVLLIVKMLETELLERLYKYSLSLGMEPLVEVQTAEEMTTALKLGSKAIGVNNRNLESFEVDMNTTSRLRSMVPENTIICALSGINSHQDVILCKNDGVNAVLVGEAIVRAPDTTKFIRELCSGTDAEPEPVKTQPLFVKICGTRTPEAALEAIKAGADFVGICLVPGAKRCISDETASAISEAVHTFVPTTTRTPTSIPTKSATDYYTASVARLSSSRPLLAGIFQNQPLDEVLEKQKRFNLDIVQLHGNEPVEWANLIPVPVIRAFKPSNVGIGKRGYHTIPLLDSGAGSGKLLDVSSVKEILAKDQELQVILAGGLNPDNVLEAVNAVGEFGDRIVGVDVSSGVEEDGKQSLEKIRTFVKNAKSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ45</accession>
    <name>A0AAD8XQ45_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Solute carrier family 35 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_746431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371545.1">
        <property type="nucleotide sequence ID" value="XM_060513272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ45"/>
    <dbReference type="GeneID" id="85397170"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44082" checksum="4B06FD6DF47DF3D0" modified="2024-05-29" version="1">MAADDDTTKNLNTAPVTTTQITAGHDESELVGQGLHDIEARKVHWWSYFTTVDFWIVLIIGQILALCITSTNTFTSFLANNGVSIPAFQTVFNYILLFLIYFPVTIYKYGFKKWGKLLLRDGWKYFILSFLDVEGNYFTVLAYRYTNILSAQLLNFWAIVVVIILSFFLLRVRYKVFQIVGIIVAIGGCGVLLASDHITGSNGGPGIDMVKGDLFALLGATLYGVTNVAEEWFVSRRPVYEVLSFMGMWGMCINGVQAAIFDRESFREATWNGPAIGYLLGYTFALCLFYSLVPLLLRMASAAFYNISLLTGNFWGIIIGVNVFGYSIHWMYPIAFVLIILGQVAYFLAGSMLGDSKKPWLGDNQENGVAGLGTAKLKAINAARKRQMAAAEPPAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQG7</accession>
    <name>A0AAD8XQG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-terminal C2 in EEIG1 and EHBP1 proteins-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_564551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371647.1">
        <property type="nucleotide sequence ID" value="XM_060503654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQG7"/>
    <dbReference type="GeneID" id="85387553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="53174" checksum="033477CF6494B84A" modified="2024-05-29" version="1">MSPLKSMANGGFLPTVNKNRKPKFELHLKIFDLNNVPLVSGTSIVKWNLAHSIHAEHRGRTPQCPISNHKVEYNYSKVVSHIRISIDKNNNLTECPVEFEVLQQFPGSGREEKISLGIVKLNLSEYVEESDGLTRESASFDRGHSRKRSSGTSQSPMSTRAPALDDPDVEDGIVRRYLMQESKINSTLKIGILMMQLDGDKNYSAPPLKTAPVFGGIAGIMAGEAVEQDDAGQLPTMAKSRDASEVQDMYRRALAASWSCQPGELPADQCIEDIFSGGDGWQAGRTGRTGKKTATFDLDNGGSLSSDEGGMNGTLRPSDFRKLERKQQQQHQHQQLLDPPQQDHLHLHRLHNGHRHHSRNNSGSSDRSMRSLRSIKSMATIVTGRGDAASSTAGASNVARRGSHSRTRGRDDDQRLGVGGGGGGGNGGGISARDYGRSRSRSGSMVSLAPTMGSSDRGRESSRRNRELEEFDVRDDLVAWRLPGAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQX5</accession>
    <name>A0AAD8XQX5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_746170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371806.1">
        <property type="nucleotide sequence ID" value="XM_060513221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQX5"/>
    <dbReference type="GeneID" id="85397119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042052701" evidence="1">
        <location>
            <begin position="23"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="60" mass="6364" checksum="8582A381AFE74132" modified="2024-05-29" version="1">MQFPAVFSMVLAIASLGAFVQARPSPCPDWKRDDILNGKASPEICCSYGVCKGDVVVMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQZ6</accession>
    <name>A0AAD8XQZ6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_3355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371812.1">
        <property type="nucleotide sequence ID" value="XM_060502441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQZ6"/>
    <dbReference type="GeneID" id="85386340"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="14243" checksum="04745D2E4A16E2AA" modified="2024-05-29" version="1">MGRTTSKSPLCQYAAWLGHLYHIFTWSTVVCLVKKAQALHGAGGHEPGRYLWYYLLVPILGTWTSSKCLRPLRHSFLSRPASASNVAATGYQAWIRICLDVYLAMLAFLCISYLTFTIRNSPCGFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XR29</accession>
    <name>A0AAD8XR29_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_9099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371951.1">
        <property type="nucleotide sequence ID" value="XM_060515999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XR29"/>
    <dbReference type="GeneID" id="85399897"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042219983" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12003" checksum="B3894E615B13544A" modified="2024-05-29" version="1">MQFSHCSFFALSPIFLQCVIAPKMEASFRLLCFLLLPSTDTPPLSVSLSLSHTNGNTTYPNPTQHYLVHQLNPVSGFSSLASHGPGNAMCPPIKPSGSFGHCCWPRLWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYV8</accession>
    <name>A0AAD9CYV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_763959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369033.1">
        <property type="nucleotide sequence ID" value="XM_060515224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYV8"/>
    <dbReference type="GeneID" id="85399122"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140115">
        <property type="term" value="P:export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF145">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="45"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="53184" checksum="4AB6E66CFCA9F7B6" modified="2024-05-29" version="1">MNIDLQVVLNRCVPNLDRAPEFEVKWDSEYVQDPRSWPTWYKVFTVTTVSLGATVVSLFSTLYTSGIPGLQAEFHVSKLVALLGLTTYLLGMAAGSLIVAPMSESLGRRPLYIASMAAFLVLVLPSALAESITTIIATRFFGGFFGSTMMSNSPATVNDIVSDKHRALALGFWSIGPANGPVYGPLIGGFVYQYMGWRWTNWIVLIVGGVVFVLLASVKETYAPVLLRRRAAERSKATRDNRWWTRYDHGQGLWPLLKINLYRPLKMMCTEPICMFWNTYIGIVYATLYLCFVAYPIAFQQERGWAPGIGGLAFLGIGCGTLIPIAAEPLLRRIVNLHQKDPATGNVKPEARVSVVCIGAVLLAVGQLWFAWTCRPGTHWIVPILAGVPYGAGNACTFIYANNYMAQSYGIYAASALAGNMVVRSIMGACLPLAGPSMYGTLGLNWAGTLLGLVEMLCVSVPVAFYFYGYKIRQGSPMIQEITKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYZ9</accession>
    <name>A0AAD9CYZ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_87056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368974.1">
        <property type="nucleotide sequence ID" value="XM_060515968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYZ9"/>
    <dbReference type="GeneID" id="85399866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160668" evidence="7">
        <location>
            <begin position="21"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="705"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="14"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="282"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="760" mass="86131" checksum="D610AABE6B0DC504" modified="2024-05-29" version="1">MRLSPLFLFLGTTLLSGVQAAEADKDDRENTYFNSMKVPPILELTPDTFDKEVKASQFMLIKHYSPYCPHCIDYAPIYQTLYEWYYTSKPESKEDKTFTELYDFRFATINCVAYFDLCASHNVASYPSTILYKNGELAELIKGVKDIDQISPIIEKYLEAAKPGTRPRSLEYPEPGDKTSPEKAPGKADDSKKPGDDKADAKTDAKTDSKTPAKADEKTPPKEETKAPPKAPPAKEDDKPAGKTDAKADTKGDAKTETKTDAKADVKADAKPSTTTEKAIAAPTKAVVKKPTVTPNKEGASVPLSAERFQTLVTMTQDPWFVKFYAPWCHHCQAMAPNWQQLAKEMKGRLNIGEVNCDVETRLCKDVRLRGYPTILFFKGGERVEYDGLRGLGDFVHYANKAIDISEGVLDVDAESLAVLEEKEEVIFIYFYDHATTSEDFMALERIPLSLIGKAKLVKTKDPVLFARYKITTWPRLLVSREGRPTYYQPLTPKEMRDIHQVLNWMKSVWLPIVPEMTASNAREIMDGKVVVLGIVNREDQEGFLRAKRELKSAANEWMDKQILLFQHERQELRDAKQLRIDEADDRGDGRALRAAKAIRINMDKSDRKQVGFAWVDSVFWQRWIRTTYGIDTKDGDRVIINDEDNRRYWDTTITGNNILLSRTSILETINKVVSSPPKIKPKLTISSFEKIFFDIRVTFVEHPYLTMGCILGLAFGAFSWFRSRTRKGRGGHFRLEESWGNKELMKEGLLGPNGNGKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0R6</accession>
    <name>A0AAD9D0R6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369799.1">
        <property type="nucleotide sequence ID" value="XM_060510110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0R6"/>
    <dbReference type="GeneID" id="85394009"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045014" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="17860" checksum="AB92BFE0B3CA0730" modified="2024-05-29" version="1">MKATLLASALAGFTLIGQTTAGAGATVYACVYFATKPTTPIQMNFSVENAQTHCMNNQGNDVSMTITSAPVTCVSVGYVEQKSSSSGGDTCATDKSYWALSYTSPNTGYSGSMLSRWSGHDMSLSSASGKTQFCGSSAPCGQTEVTWSGTGTIYLRLYWVYSQLKNQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1K4</accession>
    <name>A0AAD9D1K4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_378553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370713.1">
        <property type="nucleotide sequence ID" value="XM_060502700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1K4"/>
    <dbReference type="GeneID" id="85386599"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042052720" evidence="1">
        <location>
            <begin position="19"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="205" mass="21832" checksum="122F4F90F975E4AF" modified="2024-05-29" version="1">MQFFFALGLSGSCSVAAGLVYRVDGGRAWKGNGNGGYAVCGMHNSSLPPFLPLSYAPGNGGRETVRPFWDCGLLAPRQRYTIEDFPIPSIGKLVKMGSAFGVPEPLSLIAVTSRGDEDGDAATAGREIGGVELTKALFISCSSHVWNLRGLHQPFLRSMLWGRGIGIFTGPVVRIVRSWGDHRVSLTGRLTESRAASGSSLQMAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2J8</accession>
    <name>A0AAD9D2J8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_601917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370716.1">
        <property type="nucleotide sequence ID" value="XM_060507133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2J8"/>
    <dbReference type="GeneID" id="85391032"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="96" mass="10736" checksum="B4439F10084F6FB7" modified="2024-05-29" version="1">MPRLQCVTVRSLASRTRAKRNRTSLNSTCQKEHPAAQQYPDHQKKPESWFLGFLKAKVTTSREAVASSALQLPYSTPPLIQTPGFPIHPDPSSNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2L7</accession>
    <name>A0AAD9D2L7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_342555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370910.1">
        <property type="nucleotide sequence ID" value="XM_060502469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2L7"/>
    <dbReference type="GeneID" id="85386368"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041960841" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11782" checksum="9D7E8265F3CE7DF0" modified="2024-05-29" version="1">MDQCQARPTNMSNLLFVLLYTQTLLQVSSTARPRVFHQRFATTQRPERYLDSSEETLDPTRRICTSPIPVCQPSKVKVSSKLWPEFLIDWHFPLISEPTCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6R5</accession>
    <name>A0AAD8U6R5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Necrosis inducing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_555566</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000188">
        <property type="protein sequence ID" value="KAK1708934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358452.1">
        <property type="nucleotide sequence ID" value="XM_060503518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6R5"/>
    <dbReference type="GeneID" id="85387417"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1708934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="25811" checksum="19582C03B90FFD1E" modified="2024-05-29" version="1" fragment="single">NWIDHDKVAALNEATSLGLEGQLQLRFNPELFVSGGCDPYPAVDAFGSLGAGLRPTGGGRSGCGNGGTGQVYVRRGSSQGRTAIMYSYYFPKVRWAKGNDNGHTHYWASIVVWVNRWGCEGDTDVSAVFPVGVSFTRDHTVWDTAQTGDISYLESTHPKMQIHDNAMSPFTGADGDKVFERTLVAWDALPDAAERALSLVEYEKTQVPFIDANFQTYLDAAYKESFYGALTDQQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7B4</accession>
    <name>A0AAD8U7B4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_724832</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000237">
        <property type="protein sequence ID" value="KAK1705773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357677.1">
        <property type="nucleotide sequence ID" value="XM_060512699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7B4"/>
    <dbReference type="GeneID" id="85396597"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="255" mass="29444" checksum="2E82353869D0A88F" modified="2024-05-29" version="1">MHEHCCERGTIVSSTTSLADSIYNFRVENGRTYHRYKDGKYSYPNDERESDGLESRVPPNVTYEVDDIAEPRTFSLPFDYIHSRMITSSISDWRRLIQNAFDNLTPGRYLELQEMDLMPQSDDGSLKPDAAIVRCFALLGKAATALNRSFQDIPDLVNVMKDIGFVDVSIKKVKWPTNTWPKEQHYKLLGEWAHENCMSGIEGWTMAPLTRGLGWSKQEVEVFLIELLKEFKDRSIHAYWPCYGLYGRKPEATCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U936</accession>
    <name>A0AAD8U936_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase T2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_758710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000257">
        <property type="protein sequence ID" value="KAK1704796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357495.1">
        <property type="nucleotide sequence ID" value="XM_060515076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U936"/>
    <dbReference type="GeneID" id="85398974"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057328">
        <property type="entry name" value="RNaseT2L_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25488">
        <property type="entry name" value="RNaseT2L_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase T2-like C-terminal" evidence="1">
        <location>
            <begin position="25"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="142" mass="14736" checksum="2B81FA37D083895A" modified="2024-05-29" version="1">MQPKFIALTVGSFCGVFATLPRTFELLVFQNGQRIGCINGYGNFITGSLACYPFNTVGTPVEKVAIRGYEPCSVSNGSLVCYQAVGPSSLYGLTGADLDLIGNGTLFSADSLPQTSDRVGVPVDVGDDGIGAMSLQVRGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9B8</accession>
    <name>A0AAD8U9B8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_636930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359881.1">
        <property type="nucleotide sequence ID" value="XM_060509283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9B8"/>
    <dbReference type="GeneID" id="85393182"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="3">
        <location>
            <begin position="104"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="556" mass="62769" checksum="A08267595DD70783" modified="2024-05-29" version="1">MPGDLESSLLKSQPSSPSSSSQASFSSSLDDLEYARICQEDKVESFRIETLEVEDDISVADTIVAPRPLPPWLRYSKNLVLALIPSFLHPVDPDATPKPLHPSAWLDGLRGLAAFFVVCHHWSLCTLTGEFRRGFMSDDTPIFLQIPILRLAVSGLSNVCVFFVISGYALSYKPMKLIRQKKSAEFAIATASSAFRRYIRLFLPTMITSLAVAGLAYFKLFELEPIPGPLITMFRPPALDNVWDQVVGWWGHFSILSDPMAKNLDRGRTFPYQPQLWTIPVEFDGSLIVFLAHVAFYRVRPSVRIFFLVCLLVYTIHSGYWQFFLFLFGLLLAALRFYGDDEDADYESNGYDWETLPHLSSPSYWRREGLRGFSAPISFIKSSKTYCISKKTLQLASFIGALWVLSFPEGSGSVAQTPGFRTISWLTPTRYGEGDGFWIPVAAVWLVSTIDQSQFIQPIFTGRVIQYLGRISFAIYLVHNCLIWLWGYHCIQFFSAITGIPLEANLSTSWGFVVFLSTCLYLPGVVCVADFVQRYVDVNAVKFAAWFEGKLIEKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9K5</accession>
    <name>A0AAD8U9K5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_538820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000265">
        <property type="protein sequence ID" value="KAK1704413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357425.1">
        <property type="nucleotide sequence ID" value="XM_060503381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9K5"/>
    <dbReference type="GeneID" id="85387280"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1704413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21260" checksum="E39B5CACB983BBBE" modified="2024-05-29" version="1" fragment="single">LQAKSALGDSYDWDGQLLKSLSLRKKVHKARLELLGVDHPDTLHAFNRLVDTRSLLAHTQEEKEEVCRLREEAVASWRRVRGEVHPQTNEARVNLGHSYTAASRFEEALLEQQDVLAIRNEKDPGEESQETLDNKKGLASVLSAVNAAPQAAVLMEEVLRVETRHLGRDHPRTRETGALLHRYYQEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9X3</accession>
    <name>A0AAD8U9X3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dcp1-like decapping family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_184658</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000218">
        <property type="protein sequence ID" value="KAK1706959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357959.1">
        <property type="nucleotide sequence ID" value="XM_060501545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9X3"/>
    <dbReference type="GeneID" id="85385444"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1706959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="26695" checksum="50522B2E0FB13E21" modified="2024-05-29" version="1">MSRSTPRRRGGAHARHSSQGNPISGPRPVQSDYESDAAHYIDSHPVPDPNPALLNRTNTDLNLSVLRRYLPSINSTLSIAANAVVYTFNPTLPGWDKTGIEGTYFLCMQDPVPGASRPNPRACIFVLNRRGLENVILDLNEVDDFEVMDEIYIFRLRGTSEEAAEGTNKVMGIWIHADKEDTRVMNAALISETLKHVRLAEEQNAVAGIGGPGGPGGEEELGPAMQAIGRKLSLSDLFGAHNGLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAF2</accession>
    <name>A0AAD8UAF2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_639688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359068.1">
        <property type="nucleotide sequence ID" value="XM_060509448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAF2"/>
    <dbReference type="GeneID" id="85393347"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="21455" checksum="861313ABDC772D15" modified="2024-05-29" version="1">MLAYLAVFYDVQLRSASHLPEEESNSDDSDDDEIVLEHPDLVVEKLEDILGLNEDKITKFKERALQMASRAPSKPIKRSQISWPEDGPIPGPRRQRLELRITAKEEPYFYDPERPKSVSSEGLTNARVGWGTRSTPSSQRARIQWSPKPARVSQPPKSEPERPKSASKSTAAESTDTDNDTHVFTNSPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAT0</accession>
    <name>A0AAD8UAT0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GYF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_797429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000190">
        <property type="protein sequence ID" value="KAK1708876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358394.1">
        <property type="nucleotide sequence ID" value="XM_060515891.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85399789"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="3">
        <location>
            <begin position="706"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="843"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="945"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1179"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1258"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1404"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="861"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="900"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="996"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1421"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1449"/>
            <end position="1459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1708876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1459" mass="151722" checksum="B84232ACA1B5415F" modified="2024-05-29" version="1">MPSNLPSSFASAAAGQNANRDARGGRQDGRGAGSGEWARRDGRVNGTLTFRRSSTTPGQPSQPAASSETAFPSTPLDSGAIPQTPGAATYDYPAPSQYQKDSIVGVYKNGAAEIDASNVFESGWTPGHTNGSAARGWGKTNNNHNSQDPAACWNNRGDSNPVAINGMSEEEKEAFATDVNSTLKPPIQKQEGTQGPGPNGRKASLSHGSAAGYGLQSPSSASRPGTRRRETTDSNPFGSGPLASPSATRFARDDQQSFLFGRKNNDVKEQEQGEDEGAGQPQSKPPFGNLTRSNTAGNPSMGANISSLWGASQPPSAGATTGGGGGGMGSFGQFALPTPTSTIGGGNRGGSRFANLMNKEGTDSPAIKPNEASTPEATRSWRSRPRTDTDPFGGDDNLSGSAALGGAQDTSPPPIPNPSNIGMFETPVKGSTGDFGMSGLNLGRPSENEPGPASPSETNPYRSPPADRNESQEEGSGEKHHGGAAVGAEQNPGFGTVSRGFPTHAFDGSDRSQTSSAGPRGYASGWPVPLSTGTPDRERAGFGGGVFGNALFSPMGTDLQSPGLSSIGGGVFGPASAGGLGGPGTIGRSKLGSLFPAAMQAQMQGHEQENLSDSLPDLRQSNPLGAIGRNNFSVAPRDTGSPLRSGRGGVFEEMFPSDPTRTHSGFGGADHPGAAGIVHPQAFTPGASTGGEFGSTPVRQMVMPDRMRWVYLDPQGQVQGPFSGLEMNDWYKANFFTPDLRVKKVEDPEFEPLGQLIRRIGNSREPFLVPQIGIAHGPPSQAGPFSPSGNTGVIPPLSGVFPSFGRTLTAEEQNNLERRKQEEQQAMAQQRDFMMRQQAITRLQGQGPGGVPGSLHHQHSAHSLQSQPSFSSISSPIGPHTQQPPIGGGAGPTSGFFDSAAQQGSTQPPVGSGLDHFREEELATLNASERQMLANVPVPPSLAGLFPQQPVGAPANEGNLRNHLPGTEQLDKDEEGFRERLKEFEDIRAERDSEQSQEAATSQSVQEDVAQDVSAPAMAQAISNEHHKSPAPGMKEIMEEEHQLSLTQRVQQAQAAAEAAKNAAAGLPMPFPPPLPAAGTPLPAPTAQRVRSNLPEQYNRSQTGTPDTGSATEPPPLAPWAKEAASRKGPSLKEIQEAEARKAAKAEEVAAERRRLALEQEAATLREREKAIVAATGLPTTSTWGNGSPVAAASPWTKPAVVKPTPGTSTPSKQKTLADIQREEEVRKLKAKEVAIQTGLATAAAGKRYADLATKPNAAPGLAQSSTPAPPPGPGWATVGAGGKVKVPTGPASQTRSVSAAGVKPVPVVAKPAVKPVATVIAAAPAKGNVAMDEFNKWLHHELSRGLNGVDVDTFAGILVELPLEDGIIADAVYANSKTMHGAHFAEEFVRRKRLADKGIVEKQGAVDSKTGSSSSGWNEVAKKGGHKETPPAVAGDAGIQGAGFKVVPTRKKAGKKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB70</accession>
    <name>A0AAD8UB70_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane amino acid transporter protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_745369</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000196">
        <property type="protein sequence ID" value="KAK1708401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358279.1">
        <property type="nucleotide sequence ID" value="XM_060513187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB70"/>
    <dbReference type="GeneID" id="85397085"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000039">
        <property type="entry name" value="Neutral amino acid transporter (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF697">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="55"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1708401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="475" mass="51348" checksum="B5B4B788C591B824" modified="2024-05-29" version="1">MTAHEVDAGHAMPSGMNDDKIRPPSVHNEISSLKEQALTTHEVFKDTEDGVQFRTVTWQSATIMFLKIQFAMSILSVPGAFATLGAVGGALSLVGWHVLNTYTAVILGEFRNRHPECHTLADMCGRLWGRVGKELVGLQILIAQVLISAAGIVSISTAFNALSNHGACTVIFTLVGAILITMFSAVRTFSRLGWLTWFGFATFFIAVFIFVVAVTQQDRPAVAPPGDFDLGWTAIAHPTFVAGITASANIFISNSGSSMYLPIISEMRRPDQYRKAALVTGCLVLAMYLSFSLVIYRWCGVWLATPAFGSAGPLFKKISYGVALPGLIIGVGIYQHVAAKYLFVRILRDSQHLQANTVIHWTTWIGSNMTLGILAFIVAEAVPILNYLLGLAGALCFAPFSLIFPALLWMQDFSSYRKGGASKKAMYGFHVFVVLVGLFMVVAGTYSVAVSIKDAYASGLISKVFNCADNSGTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC72</accession>
    <name>A0AAD8UC72_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_175294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000206">
        <property type="protein sequence ID" value="KAK1707722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358100.1">
        <property type="nucleotide sequence ID" value="XM_060501487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC72"/>
    <dbReference type="GeneID" id="85385386"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="357"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="524"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1707722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="672" mass="72805" checksum="6574ED43272B97CF" modified="2024-05-29" version="1">MGWFDRKKAVKHGPEPVKPVPVNNHHHQNINPSQYHAPPHPPTQQSSRYATSTTQTPPYWQSQPGSQGQYQHPPPPYRHPQSQHHHQQQQQTHRPQGWSQQYPQQQHQQPIVVNQHYYLHPPPSHLALPAPPGSGPPTTTTATGHPIGLDKFTGSMVTIAKDFTSPNFLEEPNFHPHATQLINSTAACVDQIAGCFNDVMTLIDRDRMVGNEKALFTYQNGGGGSGAVQQTTSPGDAKRSGGSGGRGEKSGQRKKSKESSSPGSKGQSAAVATCVVSGGYFAKVELYANSKLPMNLPPLRLYMPTWPLLCMAAQYAERVYDHPKGAERDAHVSADWKTGTKAMVIKSVPMDHMNTIVFAIRGSATFMDWAVNLNTAPASPEGFLDDAGNSCHAGFLAVARKMVKPVAARLRQLLEEDPGRAAYSLLITGHSAGGAVASLLYAHMVSTSARAGSELNALTVCFKRVHCVTFGTPPVSLLPLKRPERAELRKSLFLTFVNEGDPIARADKAYVKSLLELYASPAPSVTGSVSGGGSGCDSGGDKKGRLAAKASKMSLRNKESKMSLAPHASGKESDRNRERRKREESGKPVWRLPPGTLSSPGRIVVLRSGDPKARPRDRKTVAERLDEGVVAQTVSDEELRGVIWGDPVCHVMKLYSGRIETLAVGAVTGRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCP5</accession>
    <name>A0AAD8UCP5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_591047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000164">
        <property type="protein sequence ID" value="KAK1710924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358984.1">
        <property type="nucleotide sequence ID" value="XM_060506395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCP5"/>
    <dbReference type="GeneID" id="85390294"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF11">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="229"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1710924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="714" mass="79800" checksum="9290E3ECFC7F4CFF" modified="2024-05-29" version="1">MLCQICVGAFQHRKGWVRDTDEGSEPTILLAHHESVASLEASALDACEICRPFWLQISEEDQTRLREFDAVWTLRPGAGGAKSKTPGQRLDEFDGLVTMGAVVLLEEPSLKAIGSDLMLSISFESGFTDEIHFDQKNISGTYVVQRGDYKDAGKMVPFSSSNTDSEEAWAKANSWMQACLSTHTACNVELKADPWYPTRLLDLEADCGGIDVARLVITAEHSPSHNDRYATLSHCWGSAQFLQLKKATCDDFKRGIELSKLPKTFREAVQVTRRLGVRYLWIDSLCIFQDRDDLSDWLVEAGLMHKVYSNSFCNISAAGARDSSKGLFFERDPRVSLTTDMCLNAEGFGLETEYVDCSIVDMSFWGHAVGQCHLNKRGWVLQERLLSPRVLHFGRDQLFWECREQVAAECYPEKMPEILANSVPTKFKRLSKGAYGPDAMSREREPDDPTFYHRIWDLIVRAYGSTRLTMASDKLLALSGIAQHFETLVDDTYVVGMWRKHLASNLLWHVDKETQVDGSPSVRPDAYRAPSFSWASVDGKILTGPLVDQSNLLIDVDDVQIEYVSSNKTGLVKGGHVDLRCCVLPFKIFVESIGQRQFLFLKVNGAIVMASRKDAQRDTGPLIHMDVGQRSFNDENAAGSLYYVVAQKQDELDGFVRCILLMAVDEGRKVFKRIGLAVTSEVEEIEMLQNAANVADGDVSSNGGLHGVRTIRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCR3</accession>
    <name>A0AAD8UCR3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_587690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000118">
        <property type="protein sequence ID" value="KAK1716054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360448.1">
        <property type="nucleotide sequence ID" value="XM_060506067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCR3"/>
    <dbReference type="GeneID" id="85389966"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="277"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1716054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="58840" checksum="A1DF9CC5496BEEC5" modified="2024-05-29" version="1">MPPHDIWSQDAFQHSSYNPTPIPRRPHPQPQPGASNSSSSTRVNVNTRSSEPGPSDAVTKEFFKHSSAKRVNTDALISKALKEQYPHLELVVVPESLGYGNGCNLLAYAQGGHATFEVIDDKDGSNLPSSLEWLLYLPPSRRMDGNLGGLATITSFGKYLYKWQGHEFIVYLVDGRDGVMPYPIKNYYVLAPQTYHVDQLVLAAGKWSSDLHEEVWVFDQGYWQKSHELFKSFRDASWENVILDADMKKALIEDHLSFYNSKETYQNLKVPWKRGLIYYGPPGNGKTISIKATMNMLFQKDITTLYVRTLASFMGPEYSIQQIFGKAREYAPCYLVLEDLDTIVSDDVRSYFLNEMDGLKANDGIFIIGSTNHLDRLDPGISKRPSRFDRKYFFPDPNLEQRIAYCHFWQNKLKSNKEIDFPDQLCEAIAKITDKFSFAYIQEAFVAALLAIARRSDHRGSRKRDSIEALTEQLEDDWLGVVDDAEDDGDLKKLTLWVEIKKQIEILRDGMEEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEW2</accession>
    <name>A0AAD8UEW2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_45502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360495.1">
        <property type="nucleotide sequence ID" value="XM_060503176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEW2"/>
    <dbReference type="GeneID" id="85387075"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="51046" checksum="08FD58B30940F8E6" modified="2024-05-29" version="1">MIKELQTLLETEEVTMSVVQSLVDLYQSQLASIPLLRELLQLQGPSQHGPQGMEEILKTIRKDLKPIETRAMREPPTVRLKMKGHTEYLEAATALKPSQIMEIVSRIRTRERKSKRSAQQQIRGTVDNAPDDGVHGHEQSCWDAVLGARIDRNVLKLFCKDDNAVQDIYSRSNIVCQELKLGELEQVPENYYVEVHGLRLSREEFEQNHNRDEAWGKENSVKIVHSARTFGRTVLTLTDEKDALRLCNEWVYLSGSKVAAEAVDIRSVPLFCVNCCGPGHFKDQCTNSQRCGKCAEEHSTFLCKAIKQRCPNCKNEGLRDIKDQGHTAWSPECQSVATKRMFDNCKQLASVKVPWASSSAQHQTTCETCQTTAPPKTRRNRKIQLGHHQCRRLSAVRTAATASKSWVCRWVRMGPKLRRGATKPCRRPEPPQAVPLWDLRLKFPMPSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF49</accession>
    <name>A0AAD8UF49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_405682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363132.1">
        <property type="nucleotide sequence ID" value="XM_060502870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF49"/>
    <dbReference type="GeneID" id="85386769"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="558"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="92"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="600"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1723077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="628" mass="66762" checksum="EF77AD0EDDD1B54C" modified="2024-05-29" version="1">MASISSGLAVVYPVDEGSGKFGSVTPLQRGPLDENHHQILSPPQFQEPPISTIRTPSIQDEYLSNATDADPPLPSNPTTAVPKLSGTSITLTMTSLCLSATLSALDMTIVTTAVPNIVASLDSVAGYIWVGSAFILGFTAVTPVWGSVADLWGRKPIILLALTIFLAGSLLCALAPHMDALIAGRAVQGVGASGMGVMVNTIICDLFSLRDRGLYLAVTSVIWAAGSAVGPVLGGVFTTRLNWRWCFWINLGGVVFIVLIFFLDLPSPNTPVLAGLKAIDWTGSALCMGGALMVLLALDFGDVVHPWSSATVICLIVFGAVVIGIFLVNEWKFAANPVLPLRLLSSWSKAAAYSVFAFNAYVFIGITYYLPLYSQAVLGANALTSGLYMLPLIVSCSLSAAFAGVFIQRTGRYRMLMYAAQVLLILGTGLLINLEFDKNLAKLFTFQILTGVGVGLNIEAPVLAAQAATTVRDTAAVVATMGFLRSIATAISVVVGGVVFQNQMKAENPDLVEMIGGELAGQFDGENASAHVEDIALLAAEQQVPVRQAYFRALKTVWIMYVAFSGLALVLNLFVSEHHLSDERKAAVLGVDRGNPGLLDQPAQGEEIPFETTGRQRDNVHQLRNRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFD6</accession>
    <name>A0AAD8UFD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_630269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362038.1">
        <property type="nucleotide sequence ID" value="XM_060508814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFD6"/>
    <dbReference type="GeneID" id="85392713"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042032794" evidence="1">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="73" mass="8006" checksum="74AFCADAABDE2581" modified="2024-05-29" version="1">MQLTQLLLAIVPFIGVSQAILCSCDRSTTASITCCPDIQKWNGYECEPADRQAYTDCCADQFSTTTFCRDGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH07</accession>
    <name>A0AAD8UH07_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aflatoxin B1 aldehyde reductase member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_628215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362747.1">
        <property type="nucleotide sequence ID" value="XM_060508678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH07"/>
    <dbReference type="GeneID" id="85392577"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="39319" checksum="C43BAB00CBD11B45" modified="2024-05-29" version="1">MCYLYQQQFYYLLIASLSPFRRQILIVQMSSASKQPVNLVLGVANVGDSSADPMARYDTPDQVNSFLDVFARRGYNQLDTSRMYSPQAPTSSEPRLGAANAGERFTIDTKVTSRSPGCHTKDNILKEIDESLRALKIKQINIEYLHMPDRTTPFGEACEAMNQAIGEGKIKKWGISNYSAAEVQRFVDICQERGLVKPSVYQGHYNPLVRGGEKDLFPVLRENGIAFYGYSPAAAGFFAGNHKTVKAGGRYDTSIPVGSIYAKFYVKESIMTATEKAIDVASKHGIGGHAAALRWTVYHSVLSKEHEDSVIIGASSPEQLEANLDMIKQGPLPEDVVSALEELHEQIVDKIPYHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHA3</accession>
    <name>A0AAD8UHA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_634589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360665.1">
        <property type="nucleotide sequence ID" value="XM_060509109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHA3"/>
    <dbReference type="GeneID" id="85393008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="306"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1716735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="394" mass="43841" checksum="5C43F803187CB6B8" modified="2024-05-29" version="1">MPPKKQVVEEKILLGRPGNNLKSGIVGLANVGKSTLFQAITKCNLGNPANFPYATIDPEEARVIVPDERYDWLCEKYNPKSRVPANLTVYDIAGLTRGASTGAGLGNAFLSHIRAVDAIFQVVRCFDDAEIIHVEGDVNPTRDLDIISDELRLKDIEFTEKALENQKKKTRSGGKGLEHKKAMEEQATIEKILQHLKDGNEVRKGTWGPKEIEVINPLFLLTAKPVVYLVNLSEKDFIRKKNKYLPKVAEWVKEHAQGDPIIPISVSFEERLTRYETEAESKEEQKNVGAESALPKIVLQMRKVLNLGSFFTTGTDEVRQWTLRNGTKAPQAAGVIHTDFEKTFIQVLVYNFTTLKELGTEAEVKAKGKVMTKGKDYVVEDGDILLIKAGAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHK2</accession>
    <name>A0AAD8UHK2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_623165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364482.1">
        <property type="nucleotide sequence ID" value="XM_060508367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHK2"/>
    <dbReference type="GeneID" id="85392266"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF8">
        <property type="entry name" value="CYSTEINE DESULFURASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="84"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="425" mass="46398" checksum="B81FC8EF0E3D3B09" modified="2024-05-29" version="1">MAPSSTQDLFDVEHLTSSKSIDKTSSAHQPTAPDFELFRHLVPLVSSGKTTHLNAAFMPPSNLIVNEALSRFCSEALYHPSPKSRWKEDVEAVRELLGRYINTDPSTIAFVRDTTEGLGSFIRGLKFQPGDNVVILDCEHPNQAFAWLTLRSAGLEVRLVPADPENPVAADAATFAPFVDERTRAIGLSSIMFHTGQRNNVADVCAAFRHRGIHVLADLTQQVGFAAVDVKALGVSAAAFSLHKGLNSPTGFAALYVDTQVIQEMDPVPPIVGYGGVSCVGDSEDFVVPEDPIIFHPTARRYEHANMSFISAVAARAFLQFYLEVLGPRNLEQRLYSLGDVLRQSCAELGIGVVGPSERKHHAPHLHVLRLQDPRWSERLEAAGIVATTFRTGIRVSFGFYSNLEDAERLMTVIRTGLASGIPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHU1</accession>
    <name>A0AAD8UHU1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor 1A/IF-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_586293</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361010.1">
        <property type="nucleotide sequence ID" value="XM_060505932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHU1"/>
    <dbReference type="GeneID" id="85389831"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="25"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1718010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="134" mass="15451" checksum="29EF2316B4B847F7" modified="2024-05-29" version="1">MGKPKRSALQAAEDTLTPPATLEKNQAIVRVVKAEGNNLYACELPNKKDFVLELAQRFRNTIWIKRGGFVLAERYEEHDGRVMGEIINVVRDEKAWRKQAYWPKEFVKTNTYEDSDEEESNVGKMPPSDSEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI10</accession>
    <name>A0AAD8UI10_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_742961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362054.1">
        <property type="nucleotide sequence ID" value="XM_060513127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI10"/>
    <dbReference type="GeneID" id="85397025"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF7">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G01630)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="14"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="28588" checksum="D0E4F7ADC94F0CA2" modified="2024-05-29" version="1" fragment="single">MSPVRQGRKIALVGASGNLGQHTLTALLSHGIHDITIIVRNESTSQFPDNITVKRVAFDDEAALTSVLKGQEVLILQLGIPAVGLSDVFIYAAAEANVRYILPTEFGSDPEGKLIEELPEIADKRKYRELIEKLGVGSWIGVITNPWYDFCLPMGDIFGVDARTLKATLWNGGRTKMNYTTLTRAGAVTAEVVAMPDEELARYRNKCFYTTSFHVTQREVLNSVMLATGTSESDWDIRQESVDEVIERANAMSGDDAHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIB2</accession>
    <name>A0AAD8UIB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminotransferase class IV-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_794878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361849.1">
        <property type="nucleotide sequence ID" value="XM_060515825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIB2"/>
    <dbReference type="GeneID" id="85399723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="285" mass="31332" checksum="84DA723464508A4E" modified="2024-05-29" version="1">MASNDEVEAIVSDPNFEIITTFAYSAGLPYNEASLPEPYCYLLQHGIDRLQAAASDISWTAVAEDLRSIDRVQALSKQVSAHMLSTHGEASKDPGRRFIVRLAFKRDGILSIMSGPRPTSTDSLYPRTLSNITDSLSTSEIPVYLDMEPTKPSLFTKHKTTHRQSYSAAWKRAGIDEATSPAECDVLLQNENGHIMGAAFRTVYFWRGGRLVTPSSVTGCKMGVSRRWAVENAGVKETLITALDIGDGEVVWLSSAVGGFIQGKVTLERKTRDEALNVYPWPVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJF8</accession>
    <name>A0AAD8UJF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperonin 10-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_754192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362703.1">
        <property type="nucleotide sequence ID" value="XM_060514447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJF8"/>
    <dbReference type="GeneID" id="85398345"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="10"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="341" mass="36435" checksum="45DD2EAC065DB9FC" modified="2024-05-29" version="1">MSRNKAAWLTRAKNYPFKVDDAPFPTAGPGEVVIKNITTALENPAEWKIQDMGIIVQKYPTVLGADAAGLIEEVGDGVTHLKRGQRVIGYCTGLGKQNHEFGTFQLYSKADANLVSPIPGDMSFESASVLPLAIATAAVGLYKKQHLGLPLPSHNPRQTGKTVLIWGGASSVGGTAVQLAVASGLRVVTTASQRNFDKVLELGAEVVLDYHSDTLVHDALKALSGADLVGVYDAISGPESLEPISSILDQIRRCKVTVVLPTEDDYGKNMDISMMTAYQITQDAEEVQNPVWRNFVPGALKNGQLKPKPDPEVAGKGLESIQAGLDVLKQGVSAKKLVIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJH6</accession>
    <name>A0AAD8UJH6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362616.1">
        <property type="nucleotide sequence ID" value="XM_060510645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJH6"/>
    <dbReference type="GeneID" id="85394544"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042296756" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="18329" checksum="8AA67FA8E0CB7317" modified="2024-05-29" version="1">MLIFAVRIRTALFLLGLAAGRDDNAKGGAGGHAPVASRKDEDGCTNTYEQLALPRLRVTGGVSNVSRSALIPSMIHLIPGGPGDENRSNGPKKWEGRLGMIQDDTDALVYVRQLCYAYYVLRRRRRRRGKLLRRQSSLVLVCRTTDGYGNQIEAATDGRGLEICTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJJ2</accession>
    <name>A0AAD8UJJ2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_354557</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364483.1">
        <property type="nucleotide sequence ID" value="XM_060502541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJJ2"/>
    <dbReference type="GeneID" id="85386440"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1724428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="23079" checksum="ED32FE013E952085" modified="2024-05-29" version="1">MNVWRPVGFDEEYRESTQASSMIPYLYEQIRLSRIIERMMSTLFSPRSNLDDLGRRVCFDNLNLDLNRWRESLPDVAKWHKWGGSSSKTIPGVLALHLLFHSVRIALNYDQAIASRRSDADEKPQSYCVTSAQHITSLVRTYRSQYGLQHAPLVFVYGAVQASRSAKAFNITEESQSLIQMLGELSSAWSLSREVMAKVLDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJU7</accession>
    <name>A0AAD8UJU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_576028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365727.1">
        <property type="nucleotide sequence ID" value="XM_060504881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJU7"/>
    <dbReference type="GeneID" id="85388780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041914887" description="F-box domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41575" checksum="B170987FAE468A20" modified="2024-05-29" version="1">MSSLLPGHLLLLVAEHADFAQIQDLRATCRTNRALLDSYQHTVTRVNTARYPCPPRNHILASDTREREVLPKDTFDTIRELETRHRRIEEIIHGAYLAFWEEYGLQDANKADTIRANLKRALWQCSAIADLETHSIRYRDDVVPRRDPCVKSLIHQEIILHDAPPPDGWHLALREVHESNRQDVRLRQISHVRNDLSTQDLAGIVVLAHLASQGYRRYRAPTTNGLSRPEIIEMGVCMAENTIRHGVFFLYSKVAAGEGGVDEDGRHHARLLLDDTFDEMRRWEAGDPSVLPGLTMSVASTFCEKMGCEHRDMLDAACTLLRGDVWRPVKEGEEEEVEPEAGREKPTGEEVEQNIGVTGGGVEEQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKC1</accession>
    <name>A0AAD8UKC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_621433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364873.1">
        <property type="nucleotide sequence ID" value="XM_060508263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKC1"/>
    <dbReference type="GeneID" id="85392162"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="47242" checksum="BD50F81E76941447" modified="2024-05-29" version="1">MPSRSYGFSAYVTSGSIVYASCRMTLMTGARSQFRWGASTKMPKSLSPRRVPKTDPRVASFHVLHCNQPSVFPTETRIKENICRQLCFLTHQEWMLSPRVIHYTKARMVWACRTLLKCEDGENETSGDEQRLFDSARRYRQAKEGKPKNGSYVDNEEILGFYADWCDLVSTYAARSLTYESDKPVAILGLATEVGKGIAEDYTSGVFHDDSQLNEEFHAHCVLTQLLWFAKSTLARPLALRDQPHWSWTSTIGAISFLAPARAAKSCIQQLNRVQTKDSVSSWRFSARLKKWEARQEGDPSTRSGDDYYFMEFYPKGSITYGGFVTHNTKLFSGRDMAPGGWVVFDLNEWPAEPFCLAEISTNKFNEKPGGFNVMFLAEIKSDPGDGSDRRFKRLGVGQVIDQTWFDHAELVTIALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKI6</accession>
    <name>A0AAD8UKI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_753811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363096.1">
        <property type="nucleotide sequence ID" value="XM_060514399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKI6"/>
    <dbReference type="GeneID" id="85398297"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF2">
        <property type="entry name" value="DLTD N-TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G00380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="34"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="319" mass="35207" checksum="F2E55D2092BE7E2C" modified="2024-05-29" version="1">MSTFFRDVEFQTVDGLTLRGCFYPAPGRGLAAIITPGFNCVKEMFVPEVAEQFQLAGISALIYDPRSLGLSDGQPRNEIDPMKQVSDYSDALTYLRGLPEVDPEQIFFWGQSFAGCVALCAGALDKRARMVVSICPLLDFELTPQKFPRVLARSMADRESRAAGNPPVFLPVLTEDGVNPAGLGIGADKEEFDYMVNAKKYGASRHENRTTLQSYYKLIMWQPHGIMKYMYQTPVLMVIPELDQISPPDQQFDLFGTFPGPKKAHVSVGKGHLNVLSGPEFPDLIKMQVDFIRNVLAGKVDKYVGVAHGTSNGETNGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKY1</accession>
    <name>A0AAD8UKY1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_753520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363483.1">
        <property type="nucleotide sequence ID" value="XM_060514361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKY1"/>
    <dbReference type="GeneID" id="85398259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046784">
        <property type="entry name" value="Eap1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20566">
        <property type="entry name" value="Eap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="791" mass="87282" checksum="E2C7D94135F2976E" modified="2024-05-29" version="1">MALQYSAEVLIHLRESPLCIKPSALPPAEEWMGPPPDNNRTQTNVTKPATDRRSHDNPLLDQTNRRPGVDRHVSRNSANPEDIILGPPRTAFASATLRNGKPFDNDKGLKDADSPSRFNFRNRNGDTPEGDRFRDSRNTNFGRRRGDGDPQDQEGWSTVKPRKSFGHEGAERFQGRMGAGGGDRLPNERRPRDRDDRDGPRDRTHRTFDHHDKEHDHEEAEPRPRNGLSRGKSEPWFKNDNSTASNNTNSANTPEKPPLTARERIDRAKSWRDRNREAEPVEEKSTGRNYERRWERGEHRQEREPEWFDEPAGEKAGGHTEEDFKKFMESMKASRNGPAEDKAPAAAVEAAIKAEQPAVASAPAVEIGPDQFFLKFASTAGLDVSSPSEPKRETPSKSKTGGGKSSRFTSFFNAPQDDPTQRMKTEPSTPMAGLPFGGPDLSGPAPDNEKQAFQALLMKLQRSNLQSATPPASQPFQEPPPPAREHAPSSSVASPEPFQQYGGERREDPRPRMPQGSMSMSDILAPRPTMPHQQQPPAARQDQLLQELVGQRHQASSQGSGRMESNQGRNMSNTEFLMNLMRNQPEPPRTEQQLLMRMPQPQRAAQIPHAPDREPDFQQGLPQGLPQGGRGSQRQMRGQGPPGFMDEGFHHPEPEARMQPTQILQRPPPPPGLDQMNPNWIQQGGGGPPMPPQQRSIIPPPGLAGGPGRNHPMAAMFPPNFPPGAFPPPEAMAGPPPRNMPPPPGFFGGPPPGFIPPPGMPGFPGPGGPDGHGFPFDGRMPPGAAQAFRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL02</accession>
    <name>A0AAD8UL02_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial glycine transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Solute carrier family 25 member 38 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_285153</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>glycine(in) = glycine(out)</text>
            <dbReference type="Rhea" id="RHEA:70715"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365881.1">
        <property type="nucleotide sequence ID" value="XM_060502160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL02"/>
    <dbReference type="GeneID" id="85386059"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000103">
        <property type="entry name" value="Mitochondrial glycine transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03064">
        <property type="entry name" value="SLC25A38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030847">
        <property type="entry name" value="Hem25/SLC25A38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="10"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="117"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="224"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1725826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="325" mass="35254" checksum="155FEF58754EA604" modified="2024-05-29" version="1">MSQQVTPGRTKSSRHFVAGLGSGVASAVLLQPLDLLKTRVQQSGHRSLTSYLREVAAAPNKIQTLWRGTIPSALRTGFGSALYFTSLNSIRQHVAQSRLLSQAAGNRAAHSSSLPTLTPSANLVAGAVARTFAGFVLMPLTVIKVRYESNLYSYKSLLGASSDIYRTNGPRGFFAGFGATAVRDAPYAGMYVLFYELLKKQLSSLSTRKDGQNSNRPVAITTSHATLVNFSSAVMAGGACSVISNPFDAIKTRIQLQPAVYRNMYQACHKMILEEGVRSLMDGVALRMSRKAMSSALAWTVYEELMRRAERTWSSNLTTTTTAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL11</accession>
    <name>A0AAD8UL11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_621929</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364847.1">
        <property type="nucleotide sequence ID" value="XM_060508297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL11"/>
    <dbReference type="GeneID" id="85392196"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF18">
        <property type="entry name" value="MALTOSE FERMENTATION REGULATORY PROTEIN MAL13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1724792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="560" mass="63124" checksum="40B51440C63B1176" modified="2024-05-29" version="1">MVFRKHNCSLPDLKPGLAIFIIHFSDISCNRKLHYRKMEKGKKRTNYPCDGCSLRRVRCHLQGSNPPCNECRKRSVECTFLRVPRKRGPKGPRSSTTHKVVNYQEQIRQNRSGLPLPARGPTQSPRSPSTPGVENESTAQQNPLEVYIEYLDKFRDHLTCVWPIVNVESLKSRISGSPNDHDAWALAGAVCATVIAQLRLSQLRLSKQHNLASDDNSIAESFAHHAQLSHNLSNQHHQSTYYKEDTTVSLLTAFFLHIYFANTERIRLATVYLHEAISQLHLQSLHRPEILVSLAEDQRELLLRIFWLVFVTERTFCVQNCFPPCLKPIQTFPLSGFHIQGVGEVDASFQLLAQLFALLDDNIVMAADRGGVTPDSSNADNLYSALSAMAKQDFSALAPNLPETQRVNVLMTGNWIHILWWQFALSHYQMSSRMDDTMLSMLKPAKVAHETMRLLGSVSQQAIRTHGYGLELKVFRIADALIDVLACNTWLSSSLQPGCNSMLLGARDVLHSLQKALLLIGGPESLFHKKLMLVMAESQLPVPNVKNLTPCEEEEYVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL52</accession>
    <name>A0AAD8UL52_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">deuterolysin</fullName>
            <ecNumber evidence="4">3.4.24.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_671334</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Preferential cleavage of bonds with hydrophobic residues in P1'. Also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain.</text>
            <dbReference type="EC" id="3.4.24.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.39" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364892.1">
        <property type="nucleotide sequence ID" value="XM_060511125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL52"/>
    <dbReference type="GeneID" id="85395024"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11008">
        <property type="entry name" value="M35_deuterolysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001384">
        <property type="entry name" value="Peptidase_M35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF5">
        <property type="entry name" value="DEUTEROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00768">
        <property type="entry name" value="DEUTEROLYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041921282" description="deuterolysin" evidence="16">
        <location>
            <begin position="18"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="17">
        <location>
            <begin position="208"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601384-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1724837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="355" mass="37251" checksum="350931735611C43B" modified="2024-05-29" version="1">MVAKALSVALLAGAASATCPLSIEISNAENHTVNVAVTNTGSEAVSVFKGNTVFSDHATQDLLVTDAEGTALPFEGIFVNYKRTGLDAKLFQKIAAGETITVPVNAAKSYKLDGIADAKVTAIQGFRYAVGDSIPSAFKDLASCADVTSGEVEVTVDQTTAAADHISRKREEPFNSRIQKRAITYSSCTTAQTTALKTSVTDAISMAKAASTAAGTSSYYYTTWFKSTSVASKVQTIYNDVAGVQTTSPKISCTDTYSDCTDGSALLYTVPSDNVIVPCPNNGFWGFPELASQCSGDDYDRAGSMLHEMTHLYGTTDWAYGPTAAQALSATKAAANADTYEMYAESVRLGGCTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULC6</accession>
    <name>A0AAD8ULC6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_575391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366031.1">
        <property type="nucleotide sequence ID" value="XM_060504810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULC6"/>
    <dbReference type="GeneID" id="85388709"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="109"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1725976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="692" mass="75810" checksum="C46C59CFCD751DF4" modified="2024-05-29" version="1">MPDYTTGVMPLYQVHKPPFSVESPGYERVEGETLPRRHWKAKNGLRTQPHPDVHTVYDIVKRSAQVYPNEPAVGTRKLVHLHKEKKKVPKNVDGEVIEVEKEWQYFELSRYSYLTYADLLTYINQIGSGLRKLGLSKGSRVHLFATTTANWMAMSHACGSQSISIVTAYDTLGASGVEHSLLQSNADAMYIDPQLLKTASGALKKAENVKFVIYNNSSLFSDGTEVDAFKKANPDIKLVSIEEVRALGEENPVETVEAKPEDLFCIMYTSGSTGPPKGVPMTHAGTVAAITGLWTCVEECVSNKEYVLAYLPLAHIFELVLENLVLFVGGTLGYGNPRTLSDTSVKNCAGDMREFRPTALVGVPQIWETVKKGVIAKVNSSGPLIKALFWGAFNYKTFMVKHGLPGATIFDNVVFKKVRELTGGRLRFIMNGASGISDGTKHFLSMTLAPMLTGYGLTETAANGALGDPLEYTSDAIGSIPAAVDLKLVSIPDLNYYADSNPPQGEIWVKGPAVLKEYYRNPEETAKAITEDGWFKTGDIGEFDKVGHVKVIDRVKNLVKMQGGEYIALEKMESVYRGSPFVANIMVYGDGEHSRAIAVVAPNEKVLAEEAKKLGVDEHSMHTDSKVVDAVLKDLISNGKKAGLSGLEIVGGVVLCEEEWTPDSGLVTATQKVNRRAIKDKYKKQMDKAFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULV9</accession>
    <name>A0AAD8ULV9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class-V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_730085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365803.1">
        <property type="nucleotide sequence ID" value="XM_060512835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULV9"/>
    <dbReference type="GeneID" id="85396733"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="22"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="411" mass="45000" checksum="9AE2A2DA239EE250" modified="2024-05-29" version="1">MASQIDISAVRSKFPALGQDQVFFDNAGGSQTLGTVIESIRDYLTQSNVQLGASYKVGQKATASYGEGYQAGAKYINASSDEIVFGASTTQLFRNLSHTFTFDKGDEIVVSAVDHEANIASWVDLAARQGLELKWWKPTDAASTTNPKLTTENLKPLLSDKTRLVTLTHASNILGTIHDVASVASLVHESTPRGLVCVDGVAYAPHRPIDVKALGVDFYAFSWYKVYGPHTAMLYASRAAQDAHMRSLGHFFNPSESLEGKLGLAGGSYELVSAVPRVLEYLGTPDAQGWKGKVEQEGQLQATLLEYLNGRGDVKIYGETDAGTDRRVPTISFRVQGWGTKELVNAVENESEFAFRWGHFYSYRLIKEILQLDPADGIIRVSMVHYNSPVVDEIKGFIAALDKALQHKTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMT6</accession>
    <name>A0AAD8UMT6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dicer-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_222112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367272.1">
        <property type="nucleotide sequence ID" value="XM_060501755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMT6"/>
    <dbReference type="GeneID" id="85385654"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25639" checksum="AC048C59C1D4EA53" modified="2024-05-29" version="1">MHRTHRTRQILRVRIHGSSIRRRPRVLCIEPHESWSPRHTNFCPIFRFEPRHLTLHTFFDSYRPPHYLASLLIVPRYFECAGVPVLGLLGFSRSTALPRTVIRTLGLGPQVHARTIQTMTGHSPSSSGEGADPVQDDVPPNVPVLGPHNQETLSAAAEELFLNNEASSPPAEPASGNSVIMNARAYQSEMLAESMRQNIIVAMDTGSGKTQVAVLRIRAELERTTSQKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMW8</accession>
    <name>A0AAD8UMW8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_652580</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364069.1">
        <property type="nucleotide sequence ID" value="XM_060510536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMW8"/>
    <dbReference type="GeneID" id="85394435"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2210:FF:000002">
        <property type="entry name" value="ATP synthase subunit 4 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0138">CF(0)</keyword>
    <keyword evidence="4 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="244" mass="26248" checksum="69ABB07FE7DC52FB" modified="2024-05-29" version="1">MASRLARSAVGANLLRPTLARRTLPAISASIAGARNASNVPAEDPKKKAQSIVDALPGNSLLSKTAILSSSAALSVYAISNEYYVVNEETVVAFCLLAVWGGLIKYGGPMYSEWAQGQADKIKGILNSARADHTQAVKGRIEDVQQMSGVVDITKSLFAVSKETAQLEAQAYEHQQKTALAAEAKAVLDSWVRYEGQVKARQQKELAETIIAKVTKELENPKVLQQILQQSIADVEKIVSSKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UN30</accession>
    <name>A0AAD8UN30_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_719826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364638.1">
        <property type="nucleotide sequence ID" value="XM_060512215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UN30"/>
    <dbReference type="GeneID" id="85396113"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000274">
        <property type="entry name" value="ERF1 methyltransferase catalytic subunit MTQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="268" mass="28325" checksum="CFD19D24FA92E9CE" modified="2024-05-29" version="1">MLPTPDTSHVPFERVYEPAEDSYLLLDTLSAPSETTFLTSRFGSETSSSSSSSKSRPAAPLVVEIGTGSGVVIAFLAAHAATLFGTPAVLTAGIDLNGHACHATTSTVRRAVADNPSTASPLSFWLGASLGDLTTPLRPASVDVLVFNPPYVPSPELPAQSSATLVADAQTKTTFDEDSYLLSLSYAGGRDGMETTDRLIEALPGVLSPRGCAYILLCAQNKPDEVKGRIEGFGGGWKAVTVGESGKKAGWEKLQIIRVWRETEEHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP92</accession>
    <name>A0AAD8UP92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_263871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366437.1">
        <property type="nucleotide sequence ID" value="XM_060502015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP92"/>
    <dbReference type="GeneID" id="85385914"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="419" mass="47891" checksum="ED14E1B4BFEC8333" modified="2024-05-29" version="1">MYVALSYCWGGEQPGNLVGTTLERMTEEIRMEELEQTVRDAVVATRKLGFRYLWVDAYCIIQDCAQDKANEIGDMALIYKNAAVMIAAGTAARARDGFLATSRTYLPEEEFRIPMSSGGLGTVYLRTGTHIPRHAIDTRGWVLQEFMLSSRILFFSEYELLWQCQETELRGVTGEGLEYLQPLESLPWLAFNDEAGSNFGGQEEEKRYIWMTVVEQYPRRLLSDPGDRLDALKGITLELQSLWRDTNSFGLWKKWFIEQLTWSKKDCEEDGDAEDVRSARAPSWSWASLNGRVRYTGLFTTEYAKIRSMTLLEERTSPHNMVLSCPILTLDDMDQSRLDEDEEWITEYPELAEVSLEIEDRETEYLILGKTMLGDLELLIALMVVEDDACGGVYRRVGLATFIDMAVLNSARDKVITLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPP6</accession>
    <name>A0AAD8UPP6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_618753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365699.1">
        <property type="nucleotide sequence ID" value="XM_060508086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPP6"/>
    <dbReference type="GeneID" id="85391985"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="25863" checksum="3B0643FFED2D4A7C" modified="2024-05-29" version="1">MMASATESIQTQQLTLLSGLHALTIPKDNGPWRQPQPPAYSPQAQPMVFSSVASHFVRRDVTNDSQYSQRASRLPQDSILDVDEEEEEEEPSPISLRISTRIDVASDSNLIALPYSPAVQANSIAKAIVDAIYERDWTVGCPLIDENGRPRPLKLEVDAGITVRGSSNVIGTEAVITEFLRRGTHTQKKPPHRQPRREPTDSATSPSLPNRRRPASELDAPEHPVYKRARSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQA4</accession>
    <name>A0AAD8UQA4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNF2 super family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_575556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365999.1">
        <property type="nucleotide sequence ID" value="XM_060504824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQA4"/>
    <dbReference type="GeneID" id="85388723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="422"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="916"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1099"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1099"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1132"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1149" mass="130269" checksum="108EA0DC46917D49" modified="2024-05-29" version="1">MSCDESSHVEVNSANRQRQPFLLDDDDKDGDSGSEKGGFRPTIDLQAEHNIFDESIEDMIKESRRDVHDGGRAATLSYHGNDELDGLFCSSDEQVPNVERSHDAVPIKSEESDDDSGLMIINQGEASSKARERWSKPRGTRSTDLTSPPRVKQEPAADTRLNPMLEATGREPATEGLEERQAELHSKALNGAITMEEISEMYLVSSKLSQIQEAAKTESKPPKVAPSLASNVDERTAGESKKKAKRKSHAPIKTREEFWRHEGKVRLDREKKDDYRKAKGKKRLGVCQGTSRDVKRMKKSDQTLEDAGEEGVNTGIQLQINTILRTVDAIQERADAGKLPDAPVIIATTRAEQLKQLRDAAPDYFEPDLLRDQARQLLQSTKGLGPRAVRAKNGLWNVKGMLSDMHNHQLVVGAWMRSRELNTVPKMPKGGILADSMGLGKTIETLSCIVRNQASEKLRDEGKGPTLVVVPSGQTITQWMDEVRTHCNRKFARHIIHFKEKDKMDVDPLAFFNIVFASYHQLRRSIPCVETMEQKRREIADPEKYKKWLAEATGVLHRIEWHRVVLDEAHAIKNHQTHSAYASFRLKAKYRWAVTGTPLINAASEFFSYLKFIRCHGIQKFRDFERKFRAGVIFSLTHSVRTQGEYFLGQPILNLPTTKPTHQYLKLSKEEMVIFKMMEGCFRRKINRDIEQGTAANQMRSYLVMLLRLRQASTHPFLLEGMMAEYFTSNDFQSIKEKLKNLENGNTVYNQIGSWTQRQRIGMDVNTEDSQLQPFGQSDFGLAFDMSKQIQYLEKVLEIKRSKCVSCHQISPSNSCGCVFCSNCVVVHLASKGRKCPRCRRFIGYPNPLKPFDNEEGGNAGSTTQTLTDKEYAKGFDYTGFQHTEDDKDDKHAVRFLQVADRHPHLPLTPSAKLTALKETVLRWQAEAPDDKIIIFSQFNVVMKLIGRLLEAEGIDFAYLSGKQNTEQRNRAVDEFQNGDKIKVLIVSLRAGGQCLNLTKANRVILMELWWNQAVEQQAFARVYRIGQIKETHFVRFSVDTPIEQRMLQMQASKILAINTALQDDKIRAPKISLEDIGTLLGKVTFRDGVIHRISADYDDYNDDYDDDDDSSDDSSESSSEEEGNLEGFVVSDDEEEAMDSLSDESEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQG0</accession>
    <name>A0AAD8UQG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_578292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364640.1">
        <property type="nucleotide sequence ID" value="XM_060505108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQG0"/>
    <dbReference type="GeneID" id="85389007"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="99" mass="10831" checksum="9526E11A68FB7C08" modified="2024-05-29" version="1">MCEVFIYKHVKCKCVWGEIAVQCGPGMGYTTCGQFGSGIAKRPLRLQMADKRPCPTHDLYGLYDRNQARVIKKISHGIKIGAGPSKQDAGIEVPCCAVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQH6</accession>
    <name>A0AAD8UQH6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tryptophan synthase beta subunit-like PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_791677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365943.1">
        <property type="nucleotide sequence ID" value="XM_060515739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQH6"/>
    <dbReference type="GeneID" id="85399637"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000058">
        <property type="entry name" value="Cysteine synthase B, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="398"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="58972" checksum="7265FBEAE0E4E964" modified="2024-05-29" version="1">MQPRNNLNVYKGPESVKDYFSPDKAPPLPLVELPNSLNPYRQDGVRIYAKMMTMHPANNVKSMPALNLLEHGVAPDKTKTVVEYSSGSTVISMALMSRVLYDLGDVHAFLSNKTTAAKLKLMQFFGLNITLFGGPSQPEPNDERGGIRAAYRWAQESESVLNPDQYNNDLNWQSHMRWTGPQILEQLPEISLICAGMGTSGTMSGLGSFFKKKSPSVFRLGVCTAAGDRVPGPRSLALLAPVNFPWKSAVDHIEEVASHPSYSLSLELCRNGIVCGPSSGFNLQGLYQFIEKRKKEGTLSELTGEDGQIHCVTLCCDLPYQYMDEYFAKLEAEQFPPIRNSELSDVDLYRYDSAWEKDPLVALNDFYRLDKVLTRDLLFFLSKRRSDERQGWERIIAPSPDTIVVDLRQPEDFEQFSLPGSVNFPLIHSGTPSPFADPKVLASLWQELEAKLSSENEDICSQLRDKLSLIICYDGDSARVATSVLRAKGYAADSMNGGIRAMRKLGLQLEDPCGKPNVPAHHGQSVGSVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQM9</accession>
    <name>A0AAD8UQM9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_254660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366600.1">
        <property type="nucleotide sequence ID" value="XM_060501956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQM9"/>
    <dbReference type="GeneID" id="85385855"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042109449" evidence="1">
        <location>
            <begin position="25"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="96" mass="10220" checksum="8687BBC161BDBB56" modified="2024-05-29" version="1">MANTFSVKSLAVALLASHISSCDAAVISVRSDVPAGYVAAPYYPAPYGGWASDWTDSYRRAKAVVDKMTLAEKTNITSGTGIFMGCVHHHNMYGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR65</accession>
    <name>A0AAD8UR65_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">KH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_572748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367412.1">
        <property type="nucleotide sequence ID" value="XM_060504543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR65"/>
    <dbReference type="GeneID" id="85388442"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="48"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="134"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="301"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="385" mass="40437" checksum="F1ED3C8406AB6E04" modified="2024-05-29" version="1">MSATQDNIAANGNDLVGSLDQLKLDDGETRLGPDGEPAPRTDEEYAGSQLTLRAIVSSKEAGVIIGKAGKNVAELRDETGVKAGVSKVVQGVHDRVLTITGGCQAISEAYAIVARALLEGAPAMGMGGVVSNTGTHPIKLLISHNQMGTIIGRQGLKIKHIQDVSGVRMVAQKEMLPQSTERIVEVQGTPEGIKGAIWEICKCLVDDWQRGTGTVLYNPVVRTQPGTTSTISGTSNSYSSGGGRASEYSAPRVMRTGNGADFSTTTNNGGSGGSGGRPYGRRSDSDAASRGPPTHDENGEELQTQNISIPADMVGCIIGRAGSKISEIRKTSGARISIAKAPHDESGERMFTIMGTAKANESALFLLYENLEAEKMRRQTANSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US52</accession>
    <name>A0AAD8US52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_619557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365480.1">
        <property type="nucleotide sequence ID" value="XM_060508129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US52"/>
    <dbReference type="GeneID" id="85392028"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23703">
        <property type="entry name" value="mS26_PET12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058940">
        <property type="entry name" value="mS26_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26163">
        <property type="entry name" value="mS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="312" mass="34971" checksum="94DB20519407CAC1" modified="2024-05-29" version="1">MSSRCSCARLTRLPTIIVPRQANLNLTRPFSSTTAQLKVPPQHPDWIKVPTPPQSQASEEKAPIVKGTLPTPRDVFPAKENDRKVQPSYLLETAPAPTSASSTKPAPPGSRLEHRRRMAESRRENLGIALQGLYQRKQEGVETVTAERQRRLRDHQRAAVAPERADDRLTRGSVLSSLVGSASVAPNKDRYDQANASKARTARLAAKKSEARQDALMELYINASKFIVTEEELGKHLDQLFSEDFWKRQGKSMAHDADNAWDVWGQPPTVQSMLDDMLRTQQRAIDFQTSDQDRTVKRQKSIAEELTGGKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTM4</accession>
    <name>A0AAD8UTM4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine pyrophosphate enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_718065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367161.1">
        <property type="nucleotide sequence ID" value="XM_060512020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTM4"/>
    <dbReference type="GeneID" id="85395918"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02002">
        <property type="entry name" value="TPP_BFDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006203">
        <property type="entry name" value="PRK08327.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF164">
        <property type="entry name" value="PYRUVATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="4">
        <location>
            <begin position="207"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="5">
        <location>
            <begin position="413"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="585" mass="63232" checksum="96C618C543B3667B" modified="2024-05-29" version="1">MYTASFAFFEALWDAGVTHCFVNLGSDHPSIIEAMVKGQRERKGNFPRIITCPNEMVAMSMADGYARLTGKPQCVIVHVDVGTQGLGAAVHNSSCGRAPVLVFAGLSPFTIEGEMRGSRTEYIHWIQDVPDQKQIVSQYCRYSGELKTAANVKQMVNRALQFSKSDPQGPVYLCGAREVMEAEVEPYSIRQEDWDPVELGGLPKNAVNKIAEALAGAKEPLIVTGFGGRDHRFPGALVELANTVKGLRVVDTGGSDMCFPADHPGWLGLRFGIEDAVNTADVIVVLDCDVPWINTLCHPKKDAKIFHIDVDPLKQQMPVFYIAAQSRYRASSLLSIEQITAHLKGQYAAQLESAEAKEREAKVKESHKQLLAKIEEKAQPKADGEFGTGHLTRSLKKLCPEDTIWAIEAVTNTIFVHDNLQPTLPGSWINCGGGGLGWSGGGALGIKLATDFENGGNNKGKFVVQIVGDGTFLFSVPGSVYWIAKRYNIPILTIILNNKGWNAPRRSLLLVHPDGEGSRATNEEINISFDPAPDYAGIAKAAAGGDLFAARVDNAADLDGVLKKAIETVQGGQPAVLDIKVALGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UU93</accession>
    <name>A0AAD8UU93_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_570073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368700.1">
        <property type="nucleotide sequence ID" value="XM_060504265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UU93"/>
    <dbReference type="GeneID" id="85388164"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="665"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="733" mass="76332" checksum="5D0AF9E216354FA3" modified="2024-05-29" version="1">MANIVRTATPDQASRKKAGGTEAKKNIKALAVESGLSKDIASQASPSKGKSVLQLQEEDFPALGNVPRPATPAKSAAATPKIAPASIKKPPPEAATPASVPSPVLAVEAPKATKATEKPVPGILNIAAATSAAQSKQPETTTTEQSDVSAFPALPTPTTTSVASPIARAAPKTLRVVSTPKAEVPPALSSGAAFSAAARAVSSASGRPETPASEIISDSASIVSASVSASRTSSPPPTRVGTAPVRNTTKSQQRKQRKEAHKEQSASITVAPKVVETEEQAPILGRKKKQKKEKPITAAPTLVKKPVERAATPPPPPKEPTPPPKPIVERTVVDLPPPKGKAAKQAAKMAKAAEEKGKSKEGTPTTPTPPPPAPTAVAVPEESQDIADNPNTFPEVVYHALHEAGEVPTAELLALLKPFLDAHSRFDRPSAATLSNNPPPTATTKNMVSEADHAVLLTGQPVRKVMEGQRVLITPNGDCLRNLTEEEEGRYLALQKSVAVGSDQPDSFVAPRHQARPGGFSLIKGRAVPNGPPSYFPPSPNAQKMFSDDPVNKIQREEAISYINQFVLPRLNLGNTNLFPGSWKSAPGAKDALSARETAAASLNSLAPYIYGHDAAAGAGIYSAESGGSGKDIPEDETPFGGLDSPQHQQGSEGFVTDASPSTMAAAAAQVDAQQRTGAVHPKLPGTPLNAMSLMSVEDAESALGIARKETEKLEKGLNQAMKRNRRLLLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUG4</accession>
    <name>A0AAD8UUG4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000020">
        <property type="protein sequence ID" value="KAK1727988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368043.1">
        <property type="nucleotide sequence ID" value="XM_060510242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUG4"/>
    <dbReference type="GeneID" id="85394141"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="226" mass="23774" checksum="16C577871C4C92CA" modified="2024-05-29" version="1">MPSLLNGAKWVPPTSRSSAPSPDTVRYFPALQPIICGSPQTPRADGLGDTRRSPPVISSHPAPARPSHPPNHCQAPFLVALGPVIFARNAEADRGTAAAQAHGQLGGCSTIGGGLSPPPLDDLGPSPKAEVNGEPTAKLVSVPRAKVSGESSRRRNVCNLGDDEILSLRRQRLKFSVAPQEPIPNGLDRVAALSALGQGVHRLPSQLCCHSFRPEGEYLQYLSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UV20</accession>
    <name>A0AAD8UV20_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amidohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_648798</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368279.1">
        <property type="nucleotide sequence ID" value="XM_060510220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UV20"/>
    <dbReference type="GeneID" id="85394119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01309">
        <property type="entry name" value="Met_dep_hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="7">
        <location>
            <begin position="361"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Extradiol ring-cleavage dioxygenase class III enzyme subunit B" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1263" mass="137057" checksum="C6350701D7367321" modified="2024-05-29" version="1">MDSEKSGMLPPYSAADLPPPSGPRHSHHHKRWLRPRRSMKLIVGCLAFIAFAQWKQISILPSHEPASSLSAERLQQDLATCAKLRHKPQDPIGLGREKNARFVDGQRPTLIRNATIWVGEAVEGTSLEDARAGKGYSWITADVLIDYGLIQKVEADISLNSLPKDTQIWDAKGRQLTSGIIDMHSHAGVGALPELVGNQDVNEMSNDITPYVRSIDGLNPLDPQIQVIKSGGVTTSLVLPGSGNNMGGEAFVIKHAVGKHDGRTELSAEDMLADPDRNWRYMKMACGENAKRVYGKVGHSPFSRLGESWEFRHAFEQAAKLVQEQDDWCAAADKFGVESQSSYLPQDLKWESLSAALRGQVHINTHCYTIPDLEAFVDHTNEFKFPVRAFHHAHQTFLVPEILKRVWGGRPPASALFADNMYYKSESYIGSEYAGKILWENGLTPVYVSDNPVLNAQHVLFEAAKAYRYGLPYHAALSGVTSAPAELLGLGQRIGKIKPGFDADIAVWDSDPLSVGAAPVQVWIDGAAQFSDPFELNKPLDGPISPDPKLANTTEDTTDLKEVVFTGISNVWLSGEEASTANSETVNVVFSNGDIKCIGACTEEVAAAKSSSKKIIDLKNGHITETFTAFGSLIGLNEIDNEADTDNGRNPTGFSRGLDGLVLDNKKLHIAKKYGVTKAISAPKFTGGLTHSGTSVGFNTDAKHSLEKGAVWAEDVAVHRTLTLAAKRGDNPSISDAIGKLRHTLLEAVATNDTGSDPFSEAAYLKKVVNGELPLVLTVHSADTIVAALRVKATVEEALAAKSQSKESPKLRVSIIGGAESHLVASELANAGVGVLLAPFQSYSYTWDQRRSLTGAPLTNGTAIDTLLDAGVVTAIGLEEDWLIRDLGLLAGIAQKNGNGRLSEKKALDLVSSNVYKILGIEASQSKKARHFAVYEGSPLEIGGRIRAVGSGRETVSVFVTLRFPKVNWINRRKLRTSSSTMTRAAAICVAHGGGPMPVLGDPGHASITASLQKRVPKILKLNTPDAPRAVVVVTAHWSEGAPTISSGDRHDLYYDYGGFPREAYSLKYPAPGSRSIANELKQALEKEGLSPVMNSRRGWDHGVFIPLLLIHPAADIPVIQLSVLASEDPEEHFRMGRALSALRDTNVAVVGSGFASLHNMGKLRSLMMGDPSTAKRIGTQVNEWNKELTGAALLEKREDRITALSNWRKFSHSYEMHPRYGAEHFMPLLVCAGAADDEVGREYNDDFLGADIKTYYWGDVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UW38</accession>
    <name>A0AAD8UW38_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_572688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367415.1">
        <property type="nucleotide sequence ID" value="XM_060504539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UW38"/>
    <dbReference type="GeneID" id="85388438"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14521">
        <property type="entry name" value="DSP_fungal_SDP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="325"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="435"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="514"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="712"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="630"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1727360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="784" mass="84727" checksum="B6D368D310C114CA" modified="2024-05-29" version="1">MPSAAARRIYEDQIPSFMSVFDLDAETIAAQETVTLVDPKLIEMEATGKPLANPVQSLRPTMDHSHKHHDSTSTQASESAESSPTTTLSTSDCSPLSDPSPSSSPDSPVNLIPLNSFPATSFGGLGPLSSMNTMSAAETTSFGRPMTSPSPRRPKNMKGLSIQPPFMGNSASTLVSEPASPSFIKPTIPAMKRKPSQLSLKTQTSDLVMRNTLEIPGTPGMAPILQRRALKHSTSSPHMLPSLKSATFGPPGGMTFPKVLERNESGLSEFLRPTKTGMGQSFDTTIVEEDSPIRTQLASRAALDFEPYHENENNEDQKTPGYPDGPIAIYEDNVYLYLEPTADEASKFDTVINVAREVNNPFNFLPKSDEVMSDSPAVLSPIPDTAVSNASFSTAFEFPTNDRPETPTTPKAMSFSIKRPEYIHMPWDHNTDIAQDLMHLCETIETRTKEGKKVLVHCQQGASRSASLIIAYGLYRNPELSVNDAYYAAQEKSKWISPNMKLMYCLQDFQKQMSKKKTSPGSAFRPRTGRSPTKHRLTLSADAAIDIAPKEPLTAPLPGEKEGSSGSSSPKKGSPTRARGHSTPGSQPISPGPSSAPSSFSWSEKENDDSAKFGNFDVDRLMPFKPTPPVSGLAPPSSSSFFAKPPPSPGPPPSPGFGAHRFGPATGFGFSSLNLGPSLEGEEEVAAPKDRHFMVGAVPDDAALLSPRAETMTKNPLHDSNHGFPGMQFVEVPPTPSEGLFSPRETMFPRDPFYPFGRPTQVADPRSPPTKGETPIVRSIDELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWB9</accession>
    <name>A0AAD8UWB9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic ribosomal protein L18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_750043</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000024">
        <property type="protein sequence ID" value="KAK1727495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367550.1">
        <property type="nucleotide sequence ID" value="XM_060513867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWB9"/>
    <dbReference type="GeneID" id="85397765"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="12"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1727495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="193" mass="21938" checksum="014B6CE88F5C52ED" modified="2024-05-29" version="1">MDRAHKCAFYTGIDLDRHHVRSTHRKAPKSDNVYLKLLVKLYRFLTRRTDSNFNKVILRRLFMSRINRPPVSISRIVGNLDKEDKRTVVIVGTVTDDNRLLTVPKLTVAALRFTATARARITAAGGEAITLDQLALRAPTGGNTLLLRGPKNSREAVKHFGMGPHKHKKPYVESKGRKFEKARGRRRSRGFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UWI1</accession>
    <name>A0AAD8UWI1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">beta-glucosidase</fullName>
            <ecNumber evidence="4 10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_717208</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="4 10"/>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368404.1">
        <property type="nucleotide sequence ID" value="XM_060511921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UWI1"/>
    <dbReference type="GeneID" id="85395819"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF13">
        <property type="entry name" value="BETA-GLUCOSIDASE K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="403"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="709" mass="77721" checksum="A7ABFF45EA963AB3" modified="2024-05-29" version="1">MQPPPRKLVNVDQIIENATLAEKVSLLAGSDFWHSTPLPQHNVPAIKCTDGPNGVRGSRFFNPVPALCIPCGSGLGATWNPELIEQAGQLLSKECDAKGAHVWLGPTVNIIRSPLNGRGFESFSEDPHLSGMLAAAIIRGVQSRGTLAALKHFVANDQETEKMSLDVRMSDRALREVYLLPFQIALRDSNPRVVMSSYNKIDGLHVSENPMILRDILRKEWGFDGLIMSDWYGTYSCEAALNAGVDIEMPGPSRYREKEALAAVFSGKVHQHTIDERARKVLQFVNDAASARVEKEENMRDVPEDRSLNRRLAGESIVLLKNSANLLPLSPEDCDEVAIIGPNAELAAACGGGSASLRPYYTSSVLKGIRDSLPPTARVHHEPGVYGHILLPPFTEDSVCNDEGRRGVTIELFNEPHTTKQRTAFDRVTIPDTTYQLMDYEHPQKEETFFMSMRASFVPEHTGTYEFGLATYGIGDLFINDELVIDNSTDQTPGGMFFGKGSAEKRATYEMTAGKGYHLRVEAGSAITSKVKGGSLLAIPGGACRLGGCRKIAPEEGIQRAVELAKRCKYTFVVAGLNADLEKEGKDRDTMNMPPQVDNLIAAVLEAQPNTIVITQAGNPISLPWRHSASTMVHSWYGGNEAGNAVADVIFGRINPSGKLPMTFPAQLEDNPAYLAFGSDNGKVYYSEDIFVGYRWYEARKMEVAFPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXB4</accession>
    <name>A0AAD8UXB4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_610161</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368150.1">
        <property type="nucleotide sequence ID" value="XM_060507576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXB4"/>
    <dbReference type="GeneID" id="85391475"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004402">
        <property type="entry name" value="PRK05758.2-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="23737" checksum="D40897FCEF4D0653" modified="2024-05-29" version="1">MFSRQAVRTLRAAAPASRLVARAPAVRTYAAAAATEAVKPPVAVFGLDGTYATALYTAASKTSSLDPTAKALATLDAIFAKDPKLTTVLAAPTLTPEDKSAIVAELTKQAGAGSQETVKNFLAALAENNRLGLLPGITQKFAEIMSAARGEVELTVTSATQLDNKTLNRLESSIAKSSYVGQGKKLKVTNNVNPDIVGGLIVEIGDRTIDLSVSGKIAKLNKLLTDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7A4</accession>
    <name>A0AAD8X7A4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_595903</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000339">
        <property type="protein sequence ID" value="KAK1701746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357055.1">
        <property type="nucleotide sequence ID" value="XM_060506829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7A4"/>
    <dbReference type="GeneID" id="85390728"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF120">
        <property type="entry name" value="HIGH-AFFINITY COPPER TRANSPORTER CTRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1701746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="154" mass="16729" checksum="3C9F6AE86CCD7544" modified="2024-05-29" version="1">MTFFEAFQTPLYSDAWTPTSPGQYAGTCIFLIVLGSILRLLLALKPVLEDRFWRNYPAYESDKQALASHHAESIEPGQAGSVIRRDIVGRWKGWRAGAAAARATYEVIVGGIGYLLMLAVMTMNVGYFLSVLSGVWLGTFLLGGLAGGSPTIHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7J2</accession>
    <name>A0AAD8X7J2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_725101</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000279">
        <property type="protein sequence ID" value="KAK1703559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357310.1">
        <property type="nucleotide sequence ID" value="XM_060512718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7J2"/>
    <dbReference type="GeneID" id="85396616"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF316">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1703559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="428" mass="47288" checksum="ABDBCD602DDA069F" modified="2024-05-29" version="1">MAQVAIIGGGLSGLTLALYLHKSGISSAVYEARPKDFVSGGNIALSPNALRVLDHIGVYDTLRPQGFAFESVAFLNGRGGLLAKVLNGSYEEYNYPALRIRRTVLRGELIRQLELLGVPIHYEKKCAGVREETDTSATVEFEDGETVTAEFVIGADGIHSRVRSFVRPNGSKPVFQGLAGISGTYKLSDLPDVDTDTHYPCMLFGGNGSFAVMPASADGDEVSYFATFEVEERPREEWAALDADKETLAKMIKERFPIDSSWPEVVRALCHRTPTESLTLWPFYLLSAKESWSSPSRRVLLIGDATHGMPPTASGATSFEDAETLAYTLAHIKAPLFNDSARPQVIQAWEDHRKDRVSKIVDFTTQNGDLRKTSTSFIHQWIKEMTIWAYIKMVGPHMGCKWMYSYHGESVRAVLGRLGIDESKAKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X951</accession>
    <name>A0AAD8X951_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_119759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359079.1">
        <property type="nucleotide sequence ID" value="XM_060501145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X951"/>
    <dbReference type="GeneID" id="85385044"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="287" mass="31795" checksum="65CC47624B4DB781" modified="2024-05-29" version="1">MKANPRKRGSETPVPEPKRQCVALPDTRDDDAQGHPPSANVGHVREQPESGPSVFGAISTNAATSPSASELGTEQAPGTQPVDSTAPKDTSHPQPTNTGDRKNLDNQPTRTQDTQKKIMFMTLSRCRVAVYPVQVFPDLIQQTSQDMQFRRREPGGCIYRSDLIRSRAGQFHILVSHEILGKLGRSRKDQDCVVVPTSLAIRLFVVGDCHLATSIFWPTRGSVTHIRKGCDVVWESSPDWVLFLKHLSTIRPNVPELCSLQTMLFSYPVSERRPGVRHEAPHATSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9E6</accession>
    <name>A0AAD8X9E6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_735262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000165">
        <property type="protein sequence ID" value="KAK1710897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358957.1">
        <property type="nucleotide sequence ID" value="XM_060512964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9E6"/>
    <dbReference type="GeneID" id="85396862"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1710897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="709" mass="78930" checksum="C773C681890BDA6D" modified="2024-05-29" version="1">MESHSSRPKKTDIVRKRTGCQNCKKKRRKCDETRPECLACVKKGVKCSGYERPVTFRDVTTRAAESSRKFEEARWAALRLEDERRKRRRIGLTGEPSPTPQQSPTPGDVVELPARDAALTVPAPAPMPPWHSANAEGWLAGSFTLPWPLYDTSVSSSAVQDLPQQQQDVAKSSNNLRELEQATTFENSTNRLMLTSGVPNISAPVGEAQSPALTTGWDEFLVTDGSSPGSSTSTSSPLGGPTVDCQLSIPLEEVLIQHFDRNVLPLIPVALSFPNLFRQSSCFRSAVLALSASNIKLTQPLPIDPLVLRRVCDDSSVWIYYDTAVKGLQAQLQNVENYRGEELAGAALLLAYHELEAGTALGIRNHATGLDAIASKLDFAASSIPDLFKAWRMLRYDVRFMMLPTRATCNVVDNYDVSSLLDPQLAIRDILFRLHGLHARYAMEATFSQDTTAEGNSASEKVALWLMSVLGRESDRRNVRLKDFHKVNLTPDMILRQCNVFSHRLDNWHKGLCTHDMPVVNLGTDSDLISGATFETFVTYRFGDTRKALEYVIYLVCRMTCSYLRSLFDPSVQSSGTDALAKVILGIVCGMNMQQRQQFTILRVDVLLRMAAGLSEGTNFITTVLDYLLPRLISSGLTGPDIVAWVYLKSALELELRERRKGRAIRMTIDGVEEDCEMWQLVNRHPVAAFGDYNGKGYFRDCYVIECLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9U1</accession>
    <name>A0AAD8X9U1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-glucuronosyl/UDP-glucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_153790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000190">
        <property type="protein sequence ID" value="KAK1708873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358391.1">
        <property type="nucleotide sequence ID" value="XM_060501341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9U1"/>
    <dbReference type="GeneID" id="85385240"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="480" mass="52581" checksum="F6947000010F3024" modified="2024-05-29" version="1">MLVQQKTKPWILYAVPPREGHMRPALQITKHLISSGFDVTVLGTKRWKPTIEAIGAHFSPIIGLWKTLDDPSRWPDIAQASDPATRLAASLDGGFISLLPSGLESVRVALAGMRRREPGCQIFVLSDTCFSGTLALKLGTDLPELFEEDEVIKTIGIGVVPVFWTSPERPPWGSGLPFDDSEEGRAKNVRVHKETWNSAAEDRARWVLGLMGCPKPVVSLYEGLSTSIEHPFWDASTVCHDTVLQMCLPSLEFLSSDWPRKIKFAGTLPIKPIPSDLTYPRWFNDILSNSSSLQVSKPSRKKIVFVAQGTEVLDHEELIIPTMKALATCHDILVVACLCVAGATLNTSTFGNGELPVNARVVDYFPYDAILAHADVFVSNSGYGGFQHAVSNGVPMVQAGNTFDKPDIGRRIEWSDLGVFLSESPPSVSAVEQAVTEVLGDDKFKRRAEELRKEASTYDPLKMVEEEILLLATSAGSSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBG6</accession>
    <name>A0AAD8XBG6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trehalose-6-phosphate synthase</fullName>
            <ecNumber evidence="6">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_60084</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360176.1">
        <property type="nucleotide sequence ID" value="XM_060507057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBG6"/>
    <dbReference type="GeneID" id="85390956"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000007">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000035">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1715033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="530" mass="59436" checksum="B311077193C5B1F6" modified="2024-05-29" version="1">MPSLVPDEETAPGRLLLLSNRLPITIKRSDDGSYSFSMSSGGLVTGLSGLSKTTSFQWYGWPGLEVPENEIAGMKQRLKDEYDAHPVFIDDELADKHYNGFSNSILWPLFHYHPGEITFDESAWAAYREVNRLFAKAVVQDVQDGDLIWVHDYHLMLLPEMLREEIGDSKKNVKIGFFLHTPFPSSEIYRILPVREALLTGVLDCDLIGFHTYDYARHFLSSCSRILGTPTTPNGVDYNGKFVTVGAFPIGIDPEKFVEGLKKPKVQERIDALTRKFNGVKLIVGVDRLDYIKGVPQKLHALEVFLTEHPEWIGKIVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTIEFMPIHFLHQSVSFDELTALYAVSDVCLVSSTRDGMNLVSYEYIATQRERHGVMILSEFTGAAQSLNGSLIVNPWNTEELANAIHDAVTMSPEQRETNYKKLERYVFKYTSSWWGQSFVAEMTRLSQEATQSKTLKNIGGNVVGQVTKAIQGAVESVTGSKDSAEDAKETKAEKQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBY9</accession>
    <name>A0AAD8XBY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_634424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360701.1">
        <property type="nucleotide sequence ID" value="XM_060509094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBY9"/>
    <dbReference type="GeneID" id="85392993"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="510" mass="55891" checksum="781359EB517FC170" modified="2024-05-29" version="1">MYKSLGAAADLDAVLHSAFEVTIRVSIYSHRGSLERDTVSAIMTLSADSVAQATEAAANNGVSDGNKKRPYLLFCAAPATGHTYPLLQVADEMIQRGFEGTFIAGEEFHPQVKRIGAQHVSIPPMLNPEQQAIREKVPVGIPRLMFDLSNVFIRAVTPHFHVVMETLEKIRVEHPDKQVVIVHETFYMGLAPMMYGTPLPKGYTTRPPVVDINIIPIVTTSIDTAPFGPGLPPDSTESGRGRNKLLNEMFFSPMGPFGAAAKEYNDVVKALGGTRELPPALFESWQTSYDVTLQMCSPSLEYPRSDLPDAIKYAGCLPPKPIDPNYKYPEWWGEITAGNKKVVGVAQGTIAIDYTDLIIPTIQGLAHRDDIILVAILGVKGATLPEELTIPANTKVIDFLSYDALLKHADVWVLNAGYGGFLHGIVNGVPMVLGGDTEDKPEIAMRGQWTGVAVNLKTGRPTSQQVAEGVEEVLANDKYKKRVLEIKKENEDMKALDFIEKHIWEYADSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCC0</accession>
    <name>A0AAD8XCC0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_590038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000147">
        <property type="protein sequence ID" value="KAK1712566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359423.1">
        <property type="nucleotide sequence ID" value="XM_060506293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCC0"/>
    <dbReference type="GeneID" id="85390192"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="78"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="179"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="394" mass="43869" checksum="F5FB546C65D98427" modified="2024-05-29" version="1">MAKKRKLGSINHKSHFVDTVKKKTGGAPQNNNGKNNNKKKNPKSAQATESDAKKKKAQQQYHQNQEPVIPFSKEDAILLIGEGDLSFAASLATHHGCRNLTATVLEKNERELLEKYPHAVENIAQINGTASTTKPTKSKGAKGEGEGDVENDQNDSEGPAEAESPEAKEEEEEEIDEDDDEKYKPPVQNNNRVLYNIDARSMKPFTRKSAPNHRGFHMSAPTKTGIFNRILFNFPHVGGKSTDRNRQVRYNQELLVAFFTSALPSLAPKGTIVVTLFEGDPYTLWNVKDLGRHAGLQALESFKFHSRAYPGYKHARTAGVIREKKTGEASGAAWKGEERAARSFVFMRKDEAPEVQSTQKKKRKRGGEESSSEDEVSEVEMEEEFDETGGWVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCH1</accession>
    <name>A0AAD8XCH1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_437698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362227.1">
        <property type="nucleotide sequence ID" value="XM_060503085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCH1"/>
    <dbReference type="GeneID" id="85386984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="14"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1721431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="344" mass="38699" checksum="EF50A6D24BF5D64A" modified="2024-05-29" version="1">MSSKIFRIFNPGEAKKDPVEKRRAQLRSAQRSYRDRKDKYTKSLEQEVERAQNRETELMIRCEQMYAALESLTELLSRHGIGVPAAFVDSLISKSDSGMHSSLHSRTDETLTGVGVIEYSKAPEIKSKDGRAADRSPVHAKLYTAADIVVDDLQTATDALSSRQYTEKKETDLPWLKINTAVTMYDCEDNRMCEVDLIAAGMEFVLRLERPCLEHVHGDPKKPEDSTGHILTVSARTLSLHTDPSRPNEKDCVGTPSYEGAPRDILERILALSPHVCFDGEMTPAQAWKYIRSQPHFGGIELRRLWALADKLMEGIKCHGFGAVIETQNFQTLVYDALLLGTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCZ4</accession>
    <name>A0AAD8XCZ4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Life-span regulatory factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_590360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000152">
        <property type="protein sequence ID" value="KAK1711966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359290.1">
        <property type="nucleotide sequence ID" value="XM_060506329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCZ4"/>
    <dbReference type="GeneID" id="85390228"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1711966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="16848" checksum="5979663FB14D2AE4" modified="2024-05-29" version="1">MAAFDLGTHEFCLGCDKQTDGTAYCSESCRLADFEKTSTPSSVASSPGLNTPSYPWTSPRQQSNNFYLSPAYDFTNAQPYGSTPTRRSYLSSSRAPISTRRTLTTSSSNSSLCSMQSTTSSNTDGSQLSEKAKRELQAYAVSFDQARLQRRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDA3</accession>
    <name>A0AAD8XDA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360503.1">
        <property type="nucleotide sequence ID" value="XM_060514703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDA3"/>
    <dbReference type="GeneID" id="85398601"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1716109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="201" mass="22236" checksum="197ED05BB4FC42C1" modified="2024-05-29" version="1">MPRRRRHRRGKRLIGDAVLDTGVLAAAAAPSDRRNGDAEAKAAVPTLLPSRCVLLSAAVLLHDFYCCPACPDGRLKSPEETAQQARSVDVLLKISKDVAVLSEELLLLVSRRERGGDDDDMGNEQNNGGHHQNHNHNEGQSGGSSDIGRTPECEDEMNVIKRCLERLGSRWRLAGEYGRMLEQQDFAMMMQEKGHSTLRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDK5</accession>
    <name>A0AAD8XDK5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_783977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362411.1">
        <property type="nucleotide sequence ID" value="XM_060515600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDK5"/>
    <dbReference type="GeneID" id="85399498"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22041" checksum="CA54C233C36B6AF1" modified="2024-05-29" version="1" fragment="single">HEALAASKYRLISHTIHQRLLDAAYLPTVLRSIRAALFPNNAPGVSTLVAPSSDEELRALRRRCASAMLASIPPWLAGLYLGGRGLGFRWRSGPESRPGADDDDDAAPALATSESEADVPGRGGATNDNRTNDLGNGSKGNEDDDQQRMLFEIEEGILDIFSDEYCNKHLVYSILELILVRLMPELAEKGVVELWEERLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDW6</accession>
    <name>A0AAD8XDW6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_762616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360160.1">
        <property type="nucleotide sequence ID" value="XM_060515207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDW6"/>
    <dbReference type="GeneID" id="85399105"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="34"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="37"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="87"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="152"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="208"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="263"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="320"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="402"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1715017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="48720" checksum="FDE306B5E9FB2A77" modified="2024-05-29" version="1">MPSTTVAQNARAANNRRQTQDNDHRRLERPTRILDIKVWGSGENCELGLGPRITQAPRPHAQKSLLPYDVVQISAGGMHSAALTSHGEILTWGVNDDGALGRVKTPDAPEEGPRDLLDPFESTPGLVRFEHEVDVVQVATTNSACFALTSEGTVYGWGSFAGGDGNFGFLYDKPPKTTEPLPVHIPGLNSIAELAGGANHVLALTQDGDVFAWGSGEQNELGRRLLARRRFESLIPQRVGLPRHKTAKIFAGSHHSFAIDVHGKVWAFGLNNFGQCGVPTREDTGFTTIISPTVVKSLEGYTIHHIACGLHHSIACTSEGEVLVWGRCDDGQMGIHLNAVPQDNIIFDSRGEPRVLNVPTVVPGMFLSTLSLSSKTDHCLLVPSADFVAAGIDNCFAVSRGGDVFAWGFSVSHNTGLATTETVREPTEMRRSSPLTFVDAGGQFGISAGPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE16</accession>
    <name>A0AAD8XE16_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cellulase</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_627980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362936.1">
        <property type="nucleotide sequence ID" value="XM_060508670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE16"/>
    <dbReference type="GeneID" id="85392569"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF1">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="259" mass="28708" checksum="386362AB895398F7" modified="2024-05-29" version="1">MMERIIPDKLTGTINETYFSGLEDLVKDVTSKGSYAVIDPHNYGRYYGNIITSSADFGAWWKTVAARFKDNDKVIFDTNNEYHDMDNTLVHDLNQAAITNIRAAGATKQNIFIEGNSYSGAWHWIESGSGDALKNLTDPSDSTGKLLFYEMHQYLDTDGSGTNEACVSSTIGAERLAVATKWLKDNNKQGVLGEIGAGVNTQCETAVKGAIQHLADNSEQWRGVLWWAAGPWWADYMYSMEPTTGKAYGTYLPILKSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEA0</accession>
    <name>A0AAD8XEA0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_627092</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000069">
        <property type="protein sequence ID" value="KAK1723136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363191.1">
        <property type="nucleotide sequence ID" value="XM_060508609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEA0"/>
    <dbReference type="GeneID" id="85392508"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="7"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="99"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="188"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="236" mass="24581" checksum="B667275CBB5ECB62" modified="2024-05-29" version="1">MVSNCNKFYFVASGVTCSKVLSDANISLADFAKWNPNVGAECTGMWAEVNVCVGVIGGTTPTTPPTTTSKPVTTTTTTPGNGIQTPQPTQPGMVTNCNKFHWIAQGVTCSQVLSYNGISLADFAKWNTGVGADCSGMWAEVNVCVGVIGGAATPPTTTTKPPVSTTAPGNGVTTPQPTQPGMVTNCKKFHYVSEGNTCDQIISYNGITLANFVKWNTGVGATCQSMWAKTYVCVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEK9</accession>
    <name>A0AAD8XEK9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-aminocyclopropane-1-carboxylate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_584319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361913.1">
        <property type="nucleotide sequence ID" value="XM_060505746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEK9"/>
    <dbReference type="GeneID" id="85389645"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="2">
        <location>
            <begin position="69"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="417" mass="45603" checksum="3A41216761C00359" modified="2024-05-29" version="1">MLSPRAAKTASALHRPWRFAPVQTYSASSNPSGLISFGSASNALMQPAVADFAATVPLTPDVFGYSYSTAGGARLRAAMAGHLNATFSPYAPLEVEHVRVAAGATAVQCILAFALASPGEGVLVPRPVYGRFELDFRNEMGVEVVYADTTPETCFLPDVVVEEMEAAVRREMGRGLRVRAVMIVNPSNPLGRCYPRETLVAILRFCGRHKIHLVSDEVYGLSVFRSCEEMPGFTSVLSIDPAGIIDPDLVHVEYGLAKDFASSGLRLGALVSRNAALQEAFSSVVRFHSPAGPSVAIAAAMFEDRVWHDEFIASSRRAIAGAYEFVTGRLREMGVGYVEANAGLFVYIDLSPWLPPPEEEEEEGEYESDREREFALAERFVERGVFLHPGEEHCLAPGWFRLVYTQEEHIVAEGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEM2</accession>
    <name>A0AAD8XEM2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_719982</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364477.1">
        <property type="nucleotide sequence ID" value="XM_060512234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEM2"/>
    <dbReference type="GeneID" id="85396132"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="10">
        <location>
            <begin position="50"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40901" checksum="5B2981DB4430E7C6" modified="2024-05-29" version="1">MPGLDLEHEPLAADDVRILGQDPLIPPALLSSEIPMTDAALQTVVRGRNEAVDIIMGKDDRLLVIIGPCSLHDPATAIEYCARLKDLAAKLSSDLCVIMRAYLEKPRTTVGWKGLINDPDIDSTFKINKGLRISRQLFSDLTTAGMPIASEMLDTISPQFLADFISVGAIGARTTESQLHRELASGLSFPVGFKNGTDGNLGVAIDAIGAAAAKHHFMGVTKQGLAAITRTKGNEHGFVILRGGSHGPNFDKENVQKAKDTLTKKGQKQAIMIDCSHGNSNKDHRNQPKVAAVIGDQLREGEKSIIGVMIESNINEGNQKVPAEGPAALKKGVSITDACIDWDSTVDVLEGLASAVRARRERNAGSANGNEDSHKVTHLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF30</accession>
    <name>A0AAD8XF30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_624377</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364061.1">
        <property type="nucleotide sequence ID" value="XM_060508439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF30"/>
    <dbReference type="GeneID" id="85392338"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000003">
        <property type="entry name" value="Dna-directed rna polymerases i and iii subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="64"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1724006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="41741" checksum="D26003B6957DE579" modified="2024-05-29" version="1">MAPSSTPSQAELDRRRIVGINKETVTDVTSTDYPGTYAGEDHAWDLDRFASNFRVQFHHNAQHEASFSLIGVDASIANAFRRTLIAEIPTIAIENVYIENNTSVIQDEVLAHRLGLIPFTGNPEGLHKFLKWYRKPEQAGKGSFDYNTVQLRLRIECTRNPDAAPGETDPAKAFHHASVYAKDIEFVPTGRQVEFFSGEDAIRPVNPDILIAKLRPGQCIELDMHMHKGIGSDHAKFSPVATASYRLMPTITITRPIIGQDADKFAKCFPQGVIGFEKVTKKEAAVAGSGYEGHEGEKKAVVKDAMRDTVSRECLRHPEFEGKVKLGRVRDHFIFSIESTGQWDSDELFLESVKQFKTRCIRLEQQVINMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFG2</accession>
    <name>A0AAD8XFG2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_617881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365919.1">
        <property type="nucleotide sequence ID" value="XM_060508050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFG2"/>
    <dbReference type="GeneID" id="85391949"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="116"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="695" mass="76927" checksum="0B0A48763D87442B" modified="2024-05-29" version="1">MLDSSPQSKNQEPTLPLAGTKRPAPSLLPAFEPLSSSPGFPRPSKRQARPGSVGASNAYLKYPTPIPTSSTGILSSSPPRVHSRPGGLSRTLSTASERTPLGAVSSIELNENGETLLMGRSSNSSHYQLSANRLVSRIHVKARYVPAPSALEPNKIEIICNGWNGLKLHCQGRTWELLKGDSFTSETEGTEIMIDVQDARVMIQWPKRDRRDRLASPDDSAWGDSPPRSAARVAADLLQSSPLRRPSRIESPDSPTAHLSSSQRLQALLPREDGEVQIYEDSSADEPELPKLVDSGTIIGQSFATEATNSFSSELSEPEDENANDPDEENDPIVHSFGPFGADISNRLASITTASPKFPPFKRTGLPTVRDESRPSSPISAPPKSPEEAEEGEVLEDEEEVKEAEPPYENPTVRNHVVNQLAFSRLSSNPLSTIMNNLPSEERKGLTKDQLRSLIEATACIGIIQRQGKDAAGKQLESEYYYVPEFDDDDQRRLAVTDGLRKPSLRACRKQHKVSPAMLRSKEVEVNMVDFSNTTGSAPVHLEPCSNYRFSFHVFSGFLYPFCLAEAELMPCIYRAWPLVSSLLHNTFLLSIPWLSKTAIGQNQLVCTGCIAQGVFLFSNTSKYYYCTIPLLLYLRDGRPPLFYPKDSPKGARHKFTVTRPRLQTWPLPRTRTPLDEIHAASMLRSIWKRRVCVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFY7</accession>
    <name>A0AAD8XFY7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxypeptidase</fullName>
            <ecNumber evidence="6">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_630367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000086">
        <property type="protein sequence ID" value="KAK1721284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362080.1">
        <property type="nucleotide sequence ID" value="XM_060508822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFY7"/>
    <dbReference type="GeneID" id="85392721"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF432">
        <property type="entry name" value="Y, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041767387" description="Carboxypeptidase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1721284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="55889" checksum="D07A4E8BCF749998" modified="2024-05-29" version="1">MVRVTSLAVSGLALLTGFASAVATQADIKSPDFSTLSVPEHPHHAIRIKEQSDEICNAGSRQWTGWLDTGGKHLFFWYFESLNDPENDPLSLWMTGGPGGSGLVGLMLELGPCLINDNGTGTVHNPYAWNANTSMIFVDQPAGTGLSYFDEDVTPPATSYTAAEDMNIFLRIFYQAFPGLATAPFHIVGESYGGHYIPALAAEIVSYNTGSPPPDFKVPLASVLIGNGYVSPADTTWGFYDTLCTTKPGVPEPVFNESMCGLIADALPRCMYLQQACYAFPDPIVCGAATDFCFGHVDLLYYQDVKAGGRNPFDITRPCETENICYGAGDGIEKYIKTERVLAALEVPEAVGKNFSLISMDVNERFELAGDVFLSTEADVKYILENGVDVLVYNGDLDLACNTAGNVRWTNKLSWAGQVEFVARELEPWFAVKKGGETVKAGMWKQVSKKMRGGKETRLAFVTVAGSGHMVPLDQPEVGLQMVRNWLSGDFGKAVKGGPELMGEGQQEEFVSHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG26</accession>
    <name>A0AAD8XG26_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NWD NACHT-NTPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_719521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364976.1">
        <property type="nucleotide sequence ID" value="XM_060512182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG26"/>
    <dbReference type="GeneID" id="85396080"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="4">
        <location>
            <begin position="262"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="539"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1724921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="657" mass="75043" checksum="E4FBF94BEFFA8D87" modified="2024-05-29" version="1">MQDDPDSEKRELAQQYAEILASELSGSESGPGAEGPSHLKHEQVAEDLNAKVEELSQERLTVSLGSRELPIEPLFNNVSKHIIAAKDLISSAAGADPHAALACAGGLVILTFLVRPIEQREHILRGLELTSSLICRYFAMEQVYRPQAHIIEFQARALCYLQRSRPTRFIRDMFRGDTWKALIEEIERLDAQCRAIAELITHDKILTFVELPSQKTEPAIVTFNLPKPVSNDLLRRRTKLLNRLYTCLYRDRKDINPERAPGTCEWFTEHEYFRDWIVASESRMLWVSADPGAGKSVLARYLVDDVCPSTPDRTTSYFFFKDGFDDQRSASTAMCAVLRQILEQNSELMEESTVAKFEADGNHLLNSFSRLFDVLLEAAMKVETEVTCLFDAPDECNGDDCRQVTSTLAKFYKNPPDHSRLKFIITSRLYTRIQRSLQPLKTSLPTIHLRGDDESNTERISGEIGIVIRHRLQGIAQIQLLEAKEVNLLEESLLTWQHRTYLWVKLAIDFIESRLESPTQENVEIIFNSVPEKLDGLYEKILEQSANKERARKAFHIILGAYRPLSLSEISGALCVESHHQYTSQTCQEPIKKFPSYLREICGLFVTIVDGNVYLLHETAREFLAYRPGHKGYTQLSRRSRISSWPKLAFGIYSWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGD6</accession>
    <name>A0AAD8XGD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DENN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_753184</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363863.1">
        <property type="nucleotide sequence ID" value="XM_060514320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGD6"/>
    <dbReference type="GeneID" id="85398218"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032483">
        <property type="term" value="P:regulation of Rab protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001194">
        <property type="entry name" value="cDENN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051696">
        <property type="entry name" value="DENN_Domain_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005113">
        <property type="entry name" value="uDENN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296:SF31">
        <property type="entry name" value="DENN (AEX-3) DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G11200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02141">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03456">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00799">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00800">
        <property type="entry name" value="uDENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="87"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="779"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="529"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="833"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="908" mass="102316" checksum="DC091A1CF4740037" modified="2024-05-29" version="1">MAPSLNAHSSFTRPRTGDRDGRPTTRDQGDNNLIIPSRTSSLHSRITQPIPSTLNAKPQQRTPKTLTHAYMVCGVGREPSQWVKAPAPAQGKIGHMKGAVGQFWLPEILGSSPRLEQDNEIARSLHAAMRACFPHDVEICTGRSQPHCVHHAFVLQQDSSHTLYGICLRVWSRADEKRAETIRDLRKRTEPDYYDNPDETYWIPYCLSFLSRYPLYNLLGDYLRGMWIHWNKATNLFHAEEVSRILSFPAPRLNDLVRIDMKDYALCYQFPSSPTGFQNFAMWPLFCCLSIPNIVGVVEAAISPTRRIIFVSHYPAMLTMAAETVRYCVRVYEWSGLYVPVVHARHAKDLVQEPGPYILGVTAECRSLFTAPTDALVVDLDRNFVLTSSPPTALNPSQRNKFVTRLTQSLNGDVTPSGVPPHLRSAYGGGKLVPAGQIIVMRGEVESIQDPEWWNQDTVMAVMDHVCEKMGRNTGIKAVFGGSVKKPLMTKVSMRHLNEIVRERNQYSRDALEAWQDFINLKGRMDTELNKVTKRNNYLNEELESWKQQFLKFQAFAEQLTKETQDLKAKIETHKRENRRLAGLIDQQKDDNGRLNVRLGATEKQRDDALEALVLQQEIAEELERERKRNKKELAALQHTNVTILRQRDEARRVVLHLRSLIGGQSHHMEHLVQSLTKPDDLAHEIEEGFEPEMGEDGITPREADVNQARLLSAAAEANKRLSTSSFKDVADRHLKDKTDAIAHIIRNIAEQCQAAVEGLQLAQDADFDERSASAARLRAQRRRSNLSATHSDDGHETQSNATSDMGEDSLLHPASGRISSIPPTPDLVPNRSSTAMSFASSAATPERSSQQYMIHQDIPTKIVEDDEDFEEDRSESETMPQQTVGKHTDSLIHRPSGARISALGGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGS6</accession>
    <name>A0AAD8XGS6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_412991</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000074">
        <property type="protein sequence ID" value="KAK1722805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362860.1">
        <property type="nucleotide sequence ID" value="XM_060502928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGS6"/>
    <dbReference type="GeneID" id="85386827"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="30135" checksum="EE83F1DD3B4FC8C9" modified="2024-05-29" version="1">MPSIRNTASDVPDMNLYKLNRVHRTLDKLKEKKEWEAEDTKSFDCMHYLGDSAIETAAKSLGLQAGERVLDIGSGFGGTGRYLYRHFDATTAGIELQKEIHDIAQTINEKSGAGANATSTNGNFLELDSAKMGAPFDHIVSFLCILHIPEREALFKRAHSVLKPRGKMYIEDFFARTSLDAKTLEVLRSSVSCPDLPDKKHYIAELEKAGFEVTDWVDMSTVWTDFVHERAEAYKKDPSIDADLTAFYDAVDEVFSGGQVGGTRITCQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGT4</accession>
    <name>A0AAD8XGT4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Endopolyphosphatase</fullName>
            <ecNumber evidence="3 12">3.6.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_281146</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[phosphate](n+1) + n H2O = (n+1) phosphate + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22452"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the endopolyphosphatase PPN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.10" evidence="3 12"/>
    <dbReference type="EMBL" id="JAHMHS010000038">
        <property type="protein sequence ID" value="KAK1725746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365801.1">
        <property type="nucleotide sequence ID" value="XM_060502134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGT4"/>
    <dbReference type="GeneID" id="85386033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000082">
        <property type="entry name" value="Endopolyphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012358">
        <property type="entry name" value="EndopolyPtase_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF55">
        <property type="entry name" value="ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027093">
        <property type="entry name" value="EndopolyPtase_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 12" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999171" description="Endopolyphosphatase" evidence="14">
        <location>
            <begin position="30"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="15">
        <location>
            <begin position="60"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="483"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="551"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="612"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="626"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR027093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1725746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="720" mass="80934" checksum="B910DA6614526CA0" modified="2024-05-29" version="1">MRSLPAIVGAALPLQLALLQQLCLHGVIATPVASGQQQIVIGSEVAGTVAQEGSRRLSGKFLHITDFHPDQFYKTHSSTEEGVACHSGDGPAGYYGAETSDCDTPSSLVNATFDWIAANIADDIDFVIWTGDSARHDSDESIPRSPGQVLGTNRWIADKFAETFGDPKDSSKMAVPVIPTFGNNDILPHNILLPGPNKWLGYYAEIWKRFIPEEQRHSFEFGGWFYTEVIPKKLAVFSLNTLYFFDRNAGVDDCQQPSEPGFKQMEWLRVQLEFLRERGMKAILMGHVPPARTDSKKNWDETCWQKYNLWMQQYRDVVVGSLYGHMNIDHFIVHDTKEIDINILGGFAVDDDVGREAFEDELEIQSAQDYLTELREGWAKLPAVNVKALEEEDTVESDAKDKKKKKKKPGKDLGGKYAERYHLSLVGPSIVPNYFPTLRVVEYNISGLEDAAVWTDSFTNSVPALALPSDDDPVHEELKREIDAAKKKKKGNKGKKGKKPTKPKDPNLVIPQPPPAGTGPGPAYAPQPLTFLGYTQYFANLTYLNNDMTHESKDASGNKWRDGIHKDKDPKSKKPKPRPFAFEVEYSTFTDKIYKLSDLTVRSYVKLASRIAKENAKKGKGKALAEDFEDDDEDVEEEESLDEKKELVEDGEHDDDDVDDDDEDDDKDEDVEAEEKKGKKGKKGKKGKGGKKKKKHNKVWLHFLKHAFIKTVPQKKLKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHZ2</accession>
    <name>A0AAD8XHZ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_573245</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367106.1">
        <property type="nucleotide sequence ID" value="XM_060504601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85388500"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16702">
        <property type="entry name" value="RING_CH-C4HC3_MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000287">
        <property type="entry name" value="RING finger membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057211">
        <property type="entry name" value="DUF7889"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056521">
        <property type="entry name" value="MARCHF6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25417">
        <property type="entry name" value="DUF7889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23113">
        <property type="entry name" value="MARCHF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="854"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1070"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1120"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1167"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1226"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1458"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1501"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1559"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1663"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1714"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="17">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="52"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="441"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="522"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="729"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="542"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="623"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="781"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="795"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1727051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1777" mass="196247" checksum="D97B7DC87E70ABF6" modified="2024-05-29" version="1">MDDPAMEPLAAADAYAHSRRRFSASKPDSVSHEAAKPRSQANDAGALDPDTCRICRGEATAEEPLFYPCKCSGSIKYVHQDCLMEWLSHSQKKHCELCKTPFRFTKLYSPKMPKTLPAHVFVGHMAKYLFRNVLVWLRAALVISVWLCWLPYLMRSVWAFLFWVSDEGLGSGALWNSSNATVSRGVSVAFSVANSNVCPASPLLEPTTTPANLGGMLKDIIQGQELPFSRSFHGVNITTNDSMTAALMRMLLGSITSSASANSSSVPVGTSDPVLDRHPSLLSGVSWLRNMTRYPVVNRTIIGVLEGQIITILVIISFILVILVRDYVVQQQPEINMRAAFAANDNAQPQPQPEPQHQHEQQFHGHDQEHAHAHAHDGAGMLDDYGAANLRGPSDSEDDDDESFTAGRRTSQDGLPHMAWDEREPMPELAAPLLPAGLPAARRHGGFGSRIQGGPEPEFDFNTPPEGGSNKDSQTPVATVHEYLRIYRQANGDPEKILKIIEEEKLDEPLGYWARITKSMMEKNRESGASQSKKSQAGLEGSSASRDSQATSPFSVQLPAPSTPQFSWPPQPLGESSTNGTGKGKEKEASTDFGFESGLGEEGASTSRSTPFQSPLRPRSVSDGPQMNNNINPLANNSWSFSGLNTAPQLAEPQAQEPMQSFGFDPQGQEFGLPPARFTPPRSNTPDFGSDADHDFETVEPIHEDGLFGLNEPEMQLPDDVVPAQFVGVPEEPLEDINGLPQDTEDGRPAQRPPLQRGVMDRVADFMWGDIEVRELDIGGRDDDAAHEHDHDHDSDDDDFDDDLDDDEQDAVEQDREVVEAAVAAGLDPEAIDDAEDFEGIMELIGMRGPIAGLFQNAIFCVVLVSVTIFVCVFIPYNLGRVSVWAAMNPMRLVRMLFSATKFIQDVAVGVMSGLTSLTLCFIYTTGRMMGFPAKNGVGLLMKKTFDIFTSASTRVLESLTSELPIISTTEMQNFSAISHEALLSFKSLLSGSFAAVGDVLGAIFDRDLIANTKYAASLSANATMYAWNAVRDVPIGILNPGSWVISFSVPEPSTAVNPALSYWSGTDRFWAILCGYFTFSAISALYLKRGSPFSTGQTGQDWEASLIDLLNQASGVMKVILIISIEMLIFPLYCGLLLDVALLPLFEATTLKSRVAFTVNFPLTSIFVHWFVGTGYMFHFALFVSMCRKIMRKGVLYFIRDPDDPEFHPVRDVLERNVVTQLRKILFSAFVYGALVIVCLGGVVWGLALSLPSVLPIHYSSNEPVLEFPVDLLFYNFAMPLAVKFFKPSDGLHAMYTWWFRKCARGLRLTWFLFGERRIDEEGILALRPGSDQLSLPWWRRALLEVNKENKVVPKTWEDTFEGGTAKPTSTIASDQMVILTIKKASLVKTGQLIEEGQFVRTPASDQVKIPKGRRVFMPVSESNSRLDGKDDTPDADLYSTDQYQLVYIPPHFRARVFLFIMFIWIFAAVTGVSFTIIPLVFGRKMFKVLIPAHIRTNDIYAFSIGIYILGSTAYFLFHARSIFNKMKTWASSNLQSVWQSDAPMRVALMGIHTARLAYAYTILLVVFPLILTALMELYCLIPLHTYMYPPTPYVIGTNNGGQFKDGVVVSNQHTARVIQSWTLGLLYVKLGARTITSLYEGTRLAQAVRAVLRRGWLQPDVLVLTRAFVVPGLLIGCLAIFGPPYVVGWLESQGMLGVPVPAPHELKMIYRLSYPAAAFIALAAMAFWSIVGVFNNWKARIRDEAYLIGERLHNFGVGAAGAAGARGPWRVRGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIZ9</accession>
    <name>A0AAD8XIZ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_576977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365365.1">
        <property type="nucleotide sequence ID" value="XM_060504970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIZ9"/>
    <dbReference type="GeneID" id="85388869"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="62"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="205"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="423" mass="47193" checksum="B41EABB825927E04" modified="2024-05-29" version="1">MAIAASKQRKASLPRALRALFFLISLPLLVQYILSRWNRASPSSSSASFHQSSTTPADQNANLTIWKVLSNDERVSRFAKIIGELPDIVRGLSAPQAQFTVYAPVNEAFESFYFPPDPPPFFGLFIAGYHMGPGPVPVEHLRSVGTVSSFVNGDIFFDYKQRISVQHTSTGITFNHEAKYIPRRESESKALNGHIHHIDGVLGLPNSTAHVLRTWPQLSKLREALSLTNLANSVYDTNSHVSQTMFAPTDAAFDRLGHKAVKFLFSPWGKPYLRALLKCHVVSNHTLFSDMYWPHGGVESVDFRKLSASDRHEQYDLSTLHPKLNLTVGSQKTDGRWHLDVSSSALLQAKGKSKPVYVTTSDILTMDGVVHLIDSLVLPPSAVEGEDVSWLEKMFTSLWQQDKNIENLVDLFGPYVDEEEAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ90</accession>
    <name>A0AAD8XJ90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_273948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366010.1">
        <property type="nucleotide sequence ID" value="XM_060502080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ90"/>
    <dbReference type="GeneID" id="85385979"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="54" mass="5867" checksum="0F37EAB97B0493A8" modified="2024-05-29" version="1">MLSIRHGNFCRIQVGSRKSLEGGIGQGRGSGVNTSNPQGERTAVVNFVPLRKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJP3</accession>
    <name>A0AAD8XJP3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Protein farnesyltransferase subunit beta</fullName>
            <shortName evidence="9">FTase-beta</shortName>
            <ecNumber evidence="2 9">2.5.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_570290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11535"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:86019"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="2 9"/>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368693.1">
        <property type="nucleotide sequence ID" value="XM_060504285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJP3"/>
    <dbReference type="GeneID" id="85388184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02893">
        <property type="entry name" value="FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000014">
        <property type="entry name" value="Protein farnesyltransferase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026872">
        <property type="entry name" value="FTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF6">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="89"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1728638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="52691" checksum="BCD6545696B4C772" modified="2024-05-29" version="1">MAASAQTGSPQRSDSDVDEEFIDDLSDLGIEEIETNSTVPELFTASPPVRDTLPTATSYAQDATVRECVPLLAATDSDIDQNAHGVPSLLRDNHIKFLQKQLGRFPAPYVAADASRPWFLYWSLNALALLGYDTAVYREDLIKTVRTMQNPSGGIGGGHGQDSHLATTYAVVLALAIVGGEDAYEVIDRKAMWKWLCSLKQPSGGIQMALGGEVDVRGAYCAAVIVTLLNLPLDLSTDSPAWTPERPTLFTGLADYVRRCQTFEGGISGKPDGEAHGAYAFCALGCLSILDTPHRIIPKFLDVPRLISWLSSRQYAPEGGFSGRTNKLVDGCYSHWVGGCWPLIDAVLKGAIELEDQPNEANFTPHQGSLYSREGLIRYILCCGQDRSKRGGLRDKPSRPSDAYHTCYVLSGLSSAQHQWDLTYVNEDETILSEPKWVASPCAEGTQVFNEEDRVGTIHPVYTIPQESVDDMKAYFASKQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKB8</accession>
    <name>A0AAD8XKB8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_569590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369013.1">
        <property type="nucleotide sequence ID" value="XM_060504212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKB8"/>
    <dbReference type="GeneID" id="85388111"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003119">
        <property type="entry name" value="ABC ATPase, putative (AFU_orthologue AFUA_1G16440)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF135">
        <property type="entry name" value="ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16440)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="38"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="498"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="751" mass="82909" checksum="A369EC395D3F01B8" modified="2024-05-29" version="1">MTSIASESVATILCTSKQTRFNIQTADYRELDIDGLNITVASARRSGGGSGAKGKSKARSEGTEILVDAKLRLKAGQRYALVGRNGSGKSTLLRAIAEKLIPGIPEATRISLLQQTSISDTDSDVRPEDNDSTITPSPADGSIQSSRTVLEHVIEQATARSDVEQDIRALSDGINSTDSIGPVRALRALRHERNQKHLFQVDKNARLRSGDRGLAARKALKAFEKKVAESQSLVNQQQDEISAETIKTETQEALDMLADLQLQVEPSKVAEKESKAKRILTGLGFSEAYMSKSVTSLSGGWRMRTALCISLLQETDILILDEPTNFLDLLGIIWLQRYLGSLQDTDDAPTLILVSHDRDFITICSDLLILKEKGLTYFHGDLPTYEASQSERKLWLTKMKDAQDKQKAHIQQSISNNIKAGKANDDQNKLRQAKSRQKKLDDRWGLTVSAKGGRFELNRDLVGFHLTAREEIDVPQDERPVSFVLPEPLDLRFPGPLISVENATFRYPTRGKTKLAAPTVLQDINLSVHMGDRIGILGLNGAGKSTLVKLLVDETKPTSGTVTTHPRLKLGYYSQHAVDTLQEKGQGDPSLTALSMLMEEVAGELDEGQVRGVLGSLGLPGRIASDVPLGKLSGGQLVRCELARLLWQRPHCLILDEVTTHLDYETVTAMREALRDWEGAVVLVSHDRWFMRGAVEGLIEDSDSEDDEDERGVPRRRLVYKLRQGNMTRLKSGVTEFEQSVAKRVTKLLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKY2</accession>
    <name>A0AAD8XKY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_49153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369322.1">
        <property type="nucleotide sequence ID" value="XM_060503290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKY2"/>
    <dbReference type="GeneID" id="85387189"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="132" mass="13969" checksum="D822E84CD9AD5816" modified="2024-05-29" version="1">MLVTIILGKSWALVGLHQQGLARELGPGIGFQQWRNGGKMDGEQKKMVRFTTRVGWVSAECGAVGFGVLLAFGTCAVGRGGILGAMGRSCELDVDFAMLVLSISGSACLAWRCRAFLSATAWSMQTPMGIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL03</accession>
    <name>A0AAD8XL03_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_727364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369371.1">
        <property type="nucleotide sequence ID" value="XM_060512782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL03"/>
    <dbReference type="GeneID" id="85396680"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042026216" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="399" mass="43598" checksum="F8D05F56C49FA071" modified="2024-05-29" version="1">MIPVKITAVLSLAVVACGAPLDTPLEARDAGDVLADLQAQAMENLKAAEANGTISKRGCNLFNASVRRDWAAFSTTERKEYISAVQCMLTSPSKSDPSFAPGARNRYDDFVAVHINQTRTIHGTGNFLTWHRYFTWAYENALKTECGYKGAQPYWNWFAHTDDPRKSPVYDGSDTSLSGDGAFIAHNGSVSASPYGEIAVPSGNGGGCVMSGPLVKVHLTGYSMTVNLGPVSPGMNGLDPNPHGPMEYNPRCLRRDLSSYAASTWLTTPNLLNVTVGQASKNISTFQNELQGRFWDGFLGMHASGHFVANGDASDLYSSPTDPTFFLHHAMVDRVYWIWQALHLWEAFEIAGTITILNLPPSRDATKEDIVEMGVLAQDRPIKELLSTADDTPFCYIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL42</accession>
    <name>A0AAD8XL42_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_568240</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369462.1">
        <property type="nucleotide sequence ID" value="XM_060504043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL42"/>
    <dbReference type="GeneID" id="85387942"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000595">
        <property type="entry name" value="Protein kinase, putative (AFU_orthologue AFUA_5G11840)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="372"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="77"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="331"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="598"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="747" mass="82120" checksum="8F0ADFE1EF406040" modified="2024-05-29" version="1">MPPQDAPAVRFASSVEEITPTVTTTSPTETLSPTDAATGDGEESLAEVTPDQIRALSKSLQGAPLQQRRMNVFGFEPYSLPASRVGSREEESDNSRLPTPNSSGPKSPRFGPAHPMQSPPLTPAGTDPSDPTARKSRDQNDDRKSSTSDPHVITPQASSSQDSPPSSTRKELPVRGKSTEEVPQRSASAEDQPHDTRSHRRGMFSVGPGGSVPVSRESSPSRASLYYSKPMTPGGDANDPYAAHKRQPPAPAPQRGQIDSRFVFSRRKNKHGSSPSGSTSSLGRASDKRHSGLLGMKGHGDELQVPHDDSASITSRQGSFADLKRFFKVGGHHKMKREASPSSVRSGTKTPPTRGSQHVPFGDDHGLTSKYGKLGRVLGSGAGGSVRLMKRSDDGVVFAVKEFRPRHSYETEKEYVKKLTAEFCVGSTLHHGNVIETLDILQEKGKWYEVMEYAPFDLFACVMTGKMTREEVGCCFLQILNGVTYLHSMGLAHRDLKLDNVVVSEHGIMKIIDFGSAHVYKYPFESDIVLASGIVGSDPYLAPEVYDERKYDPQAVDIWSLAIIFCCMTLRRFPWKVPRMTDNSFKLFAAEPTAGHDPKKLIMPSKSANDLSNTPQRDIFEDGKHHTHKHEPKESQKENQKEAPKDGEGSVAQGSSTQISAKSDGQQPADKKEVIRGPWRILRLLPRESRHIIGRMLEIKVKDRATMQEILDEPWVANTVICQQPEPGRVVHAEDHIHTLEPPQPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL79</accession>
    <name>A0AAD8XL79_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_32150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369490.1">
        <property type="nucleotide sequence ID" value="XM_060502373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL79"/>
    <dbReference type="GeneID" id="85386272"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="352" mass="40084" checksum="ABFB1DE83992DE37" modified="2024-05-29" version="1">MPFAQLILGAPGSGKSTYCDGMHQFMGAIGRACSVVNLDPANDHTNYPKALDIRDLVKLEDIMAGDKLGPNGGILYALEELEHNMEWLEEGLKEFSEDYILFDCPGQVELYTHHNSLRNIFFRLQKIGFRLVVVHLSDSFCLTQPSLYISNLLLALRAMLQMDMPHINVLTKIDKVASYDNLPFNLEYYTDVDDLSYLIPYLEEESPAMRNEKFSRLNEAVSNMIESYSLVRFEVLAVEDKKSMMHLLRVIDRAGGYAFGSAEGANDSVWQVAMRNESSMMEVQDIQERWVDRKAEYDELERKEWEEQAKMREDDDPNAGQAPPPPADDYDPDFGDMTIPADSGIKVVRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLH5</accession>
    <name>A0AAD8XLH5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_604429</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369672.1">
        <property type="nucleotide sequence ID" value="XM_060507273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLH5"/>
    <dbReference type="GeneID" id="85391172"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="671"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="154"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="274"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="401"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="538"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1729617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="723" mass="82794" checksum="564791CC31483EBB" modified="2024-05-29" version="1">MPVATSAPTASPRPSTLAKMEDRKRPPISTAEDLAPPSKRHQSVNGSKSKGDSGDHAEEHWIENYQKGAIYRQLLETKREKQEFETRVEQLQKNIVYREDHIRIIEAWWKQVLEEMEQLVDPATPPSGPTNPPYITSTHFKDNDEFQRHLDEAASDIKKRAEAVLNRIANARGEITPNIADLETRVNSLLAQQKEYLVKLDRAQQENEQLSEDLNKASLRFFKAEKRMDRLKSAQVQKLEQQFIASAKPTIAAGENGQDAAEANGNAAEALLKFEEASAVVNKQKEQLESAQADIKTLQEENSALKARREGLTDEDFIRTDVFKQFKNQNEDLIKRVNHLEATNKQLREEAEKLHSERTAFRTKLHDEAQTITSDLERQVEERDADLTRIRAARDEWYAKANMLETREKEEKQALQHLKELTGAQEDRIASLELELQRLKPEDQPMADPDPELESMPADELISKYKKLQQDFESINKELPALQQAYKRSMGLAQKKVMEYTVLEDRAAAALAEKQKVDQKYFAVKKDADMRDRELGVLRSQNRKSSEIVAQLKEVEAQNRILISNLEKQLSDLKQANAAMAAEHKKMESSSSDAARRVDSYKNQIGELTSLVKSRDAAMAAARERTTTQEADVERLKVRADMMQKEKDEWKRKALSNSSEEEEMLRTFALCTVCRNNFKDTALKTCGHLFCHQCVDDRISNRMRKCPNCSRAFDRLDVMSVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLR6</accession>
    <name>A0AAD8XLR6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_604513</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the second glucose residue from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide intermediate Glc(1)Man(9)GlcNAc(2)-PP-Dol to produce Glc(2)Man(9)GlcNAc(2)-PP-Dol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31307"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19521"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132521"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="EC" id="2.4.1.265"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:31308"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369703.1">
        <property type="nucleotide sequence ID" value="XM_060507280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLR6"/>
    <dbReference type="GeneID" id="85391179"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="503" mass="56799" checksum="6380F6FFB5193D54" modified="2024-05-29" version="1">MAESYPTLTQCALVAGALKVLLFPAYKSTDFEVHRNWLAITNSLPLSEWYYEKTSEWTLDYPPFFAYFEWAMSQVAKLVDPAMLKLYNLEYDSWQTVYFQRWTVIISELVLVYALQRFIDSATGPTRRAAQAAAISILLSPGLLIIDHIHFQYNGAMYGVLILSLVLARSKSGLLGSGLVFAALLCMKHIYLYLAPAYFVFLLRAYCLSPKSIFRIQFLNCVKLGGGIAAIFGAAFGPFAALEQIPQMMSRLFPFSRGLCHAYWAPNIWALYSFADRVLIYAAPRLNLPVKAEAINSVTRGLVGDTAFAVLPEITPRTCFALTLFFQVLPLIKLFFQAPPTWDAFIGAVTLCGYASFLFGWHVHEKAILLVIIPFSLIALKDRRYLGAFRPLAVAGHVSLFPLLFTSAEFPIKTVYTIFWLVLFLMVFDRLAPASRKARFFLLDRFSTLYIAISIPLIFYCSLLHQVVFGKRYEFLPLMFTSSYCAVGVVGSWIGFMVVYFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLX9</accession>
    <name>A0AAD8XLX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_567666</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.4"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 10">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369915.1">
        <property type="nucleotide sequence ID" value="XM_060503973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLX9"/>
    <dbReference type="GeneID" id="85387872"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004354">
        <property type="term" value="F:glutamate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.285.10:FF:000001">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.285.10:FF:000003">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000002">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000030">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.10">
        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006929">
        <property type="entry name" value="PRK09414.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="190"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="9">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="452" mass="49222" checksum="0F11FE59E013F8B5" modified="2024-05-29" version="1">MSNLPTEPEFQQAYNELVSTLENSSLFTQNPEYRTALEVVSIPERVIQFRVVWEDDKGKLQVNRGYRVQFNSALGPYKGGLRFHPTVNLSVLKFLGFEQIFKNALTGLNMGGGKGGSDFDPKGKSDNEIRRFCVSFMRQLSKHIGADTDVPAGDIGVSGREIGWLFGTYRQERNKFEGVLTGKGLTWGGSLIRPEATGYGVVYYVEQMLKYANKGSFAGKRVAISGSGNVAQYAALKCIELGATVVSLSDSQGCLVAEGDAAFTPEQIENIADLKVQRKSLTEFDHKGSFMYIKGARPWTHVGKVDIALPSATQNEVSKEEAEALIAAGCIAIAEGSNMGCTQEAIDVFEAQRKEKGGEAIWYAPGKAANCGGVAVSGLEMAQNSQRLSWTREEVDQKLKDIMTAAFFNGLNTAKEYVKGGETELPSLVAGSNIAGFVKVARAMHDQGDWWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM34</accession>
    <name>A0AAD8XM34_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_747907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369941.1">
        <property type="nucleotide sequence ID" value="XM_060513524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM34"/>
    <dbReference type="GeneID" id="85397422"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="165" mass="18596" checksum="D9EA00280013743E" modified="2024-05-29" version="1">MSAQDRVQNYIGQLDRELSKYPALNNIEKSTNVPKAYAVIGVASLYFFLIIFNLGGQLLTNFAGFVIPGYYSLNALFTASKQDDTQWLTYWVVFAFFTVAESLVNVVYWFPFYFTFKFVFLLWLALPTFRGAEIIFNSFLSPMLAKHFAGASTASGLRAQAGKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMB2</accession>
    <name>A0AAD8XMB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]</fullName>
            <ecNumber evidence="8">1.5.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Saccharopine reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_747954</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-saccharopine + NADP(+) + H2O = (S)-2-amino-6-oxohexanoate + L-glutamate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="ChEBI" id="CHEBI:58321"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.10" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369997.1">
        <property type="nucleotide sequence ID" value="XM_060513534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMB2"/>
    <dbReference type="GeneID" id="85397432"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004755">
        <property type="term" value="F:saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1870.10:FF:000002">
        <property type="entry name" value="Saccharopine dehydrogenase Lys9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="11">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase-like C-terminal" evidence="12">
        <location>
            <begin position="124"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00060549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00066976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00083134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1729942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="447" mass="48904" checksum="EA2D4E78191B226E" modified="2024-05-29" version="1">MASQSVLMLGAGFVTRPTLDILSDAGIPVTVACRTLESAKKLSEGVKHATPISLDVNDDKALDAEVAKHDVVISLIPYTFHATVIKSAIRQKKHVVTTSYVSPAMMELDQAAKDAGITVMNEIGLDPGIDHLYAVKTIEEVHREGGKILSFLSYCGGLPAPEASDNPLGYKFSWSSRGVLLALRNAAKYYKDGQVVDVSSKDLMATAKPYFIYPGYAFVAYPNRDSTPYKERYNIPEAQTIVRGTLRYQGFPQFIKVLVDIGFLEDAAQETLASPIAWKDATKAVVGAASSSESDLEAAIVGKAHFESPEDKQRILSGLRWIGVFSDEKITPRGNPLDTLCATLEKKMQFEEGERDMVMLQHKFEIEHKDGSRETRTSTLAEYGEPKGYSAMAKLVGVPCGVAVQQVLNGTISERGVLAPMNSKINDPIMKELKDKYGIYLIEKTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XML6</accession>
    <name>A0AAD8XML6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_426321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370225.1">
        <property type="nucleotide sequence ID" value="XM_060503010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XML6"/>
    <dbReference type="GeneID" id="85386909"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26547" checksum="2AEDC1501D13C59F" modified="2024-05-29" version="1">MYVCGSAPSGIKFQVGEMVAWLSVKVSGQRSPLPFVEHTCSGQSSSPSPSTKSFKSTDKSRRAAEQSLLREPQAPFILRIRMASRVVCWPMASFCRPSPYFRRKTQGITHRRCSYLPGHTVTSHRTTAPDIQTPVGDLSGQTLHTNGRPRGVLIGRRSCGIRRRVMECEFVTAPTFAEASRMPSGTATMGTSSTTGVPTKTTHSRRPRLRLRLPVNKCLVTIVRWLETSLVNNSVASARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XP45</accession>
    <name>A0AAD8XP45_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_599832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371127.1">
        <property type="nucleotide sequence ID" value="XM_060507008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XP45"/>
    <dbReference type="GeneID" id="85390907"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152694" evidence="2">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="302" mass="32352" checksum="CA49D0DDE9E0E3FB" modified="2024-05-29" version="1">MHLISKILYVCVALHVAFQGASGAILRGRTSDADSNQLSASDFQTLSQAAEDLNSQLDNFLRNWSGGHRKPETEETTTIVKRQNSGVSISAQDLQDLLKLIQSIERQLAAIISGSTTASGTVAPAPSNTVNNPGPLASSPAQSVVQPTATDNSPANPGVSSPTPNPVLTNTRNGGPLTTAYGTSVSTGTRCITTITQTFTEYVNEDGTTAVPGARRSVVDDVEVDAEEDDEPWVTATVPRDIEEDDEWEPWVQFDGTTTEEDESDVGFTTRDSWTELGVKRRDPLDETSSPGLLFVRDEEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ10</accession>
    <name>A0AAD8XQ10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371474.1">
        <property type="nucleotide sequence ID" value="XM_060509896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ10"/>
    <dbReference type="GeneID" id="85393795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="377" mass="41576" checksum="03C3A3AA45493807" modified="2024-05-29" version="1">MLVASTLTLLMGYDVSRKGESIQQLSPHASAVLVDSWEKVADTFPATALLLPWTLAFLRANPQLLPAQSVLSLQESKITTFQVKDQIVSGLNLNGQLQITTHRPSESISPITIHPSWAPGKPVNPTQLSPAQAASSIARAAEPGKPSHLPQVLGPPKAVIKAVKTNRATSRSLLREHKKKERQDNHIEVPKSQSRLGLASTIDFQENGSPPSSNTRTQYQSIPNFRQSLIGQVGPALPTWLHQGPLGSLTRRLWFDRPADWEHDNSTLAFIFLDEPAQDWPSLVLKRTIQRAVGREQQRIPNRTSQVHELQTFWSEIEERRDRQQIQQLNQAVGYCGNGYDNGVDVGPGSGSPTRYDTGKPGPKKGDVNLHFCSVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ30</accession>
    <name>A0AAD8XQ30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_768382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371558.1">
        <property type="nucleotide sequence ID" value="XM_060515310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ30"/>
    <dbReference type="GeneID" id="85399208"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041916278" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="505" mass="55636" checksum="0383130D4606A57E" modified="2024-05-29" version="1">MARHAIVQALPALLAIIQTASSTPLTSSILYPRNESQVVWPTEVSSLVHGKSWASFGEKTTRWSSYKAPTFDEVFLPETEEQLSLALEYMSGNNMTWLAKSGGHGYAPSLHTIQDAVLINLENFNYVKLQDDNTAVVGTGVRFNNLIDTVAAAGRELTVGSCPCVGSTGAMLGGGLGRLQGLHGLTSDALRKVRLALWNGTIIEASNNVNSDLFWGIRGSGQNYGIVIESTYETWPATNGGKHYSADLVFTKDSVQRVMEITNELTAEGLDEKLAVLMFFALDATTSQITVIVNLVYSGPEEEGRKYTDRFSSFSVDLQENMLGWEELATKTVHGLIPQSCATGPRYNLRALNTKILNPATWVNFTDAFETFLVANPLAAGSAMMIETFPVQGVKALADDYSAFPHRDHFENVIESIGSYTDDSVADAVNNFFAEWRDKFAEPSSSGYDKLYVYQNYANEDEPLSALYGYDEWRHERLTSLKNKFDPRGFFNGYHPIPPNAAGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQP3</accession>
    <name>A0AAD8XQP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_5972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371873.1">
        <property type="nucleotide sequence ID" value="XM_060506893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQP3"/>
    <dbReference type="GeneID" id="85390792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="145"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="330" mass="36056" checksum="5A275DF84E357411" modified="2024-05-29" version="1">MYNLSCVDGHRFGDVYVLDTQRLNAGLSAISSDQKLSLFDPARVGQGPIKSYQTNHGNLTCLRTFDWQNSVLCTAGENGEVSVWDMREASKPQVAHFAATQSPILSMACDPRSNTIALGTEFQNHTSSVLLWDIRAGPKQRLQYDEVHSDDVTELRFHPSESHILLSGSTDGLVNVYDTRISDEDEVVVQTLNQGSVHHASFLSNIEVYVLTHDEKLAVYSVAEDCGSGAALVDFGDARETLGCQYIANMTTKVDGSGAIVGAGSQDRQVFELVHLSRTAEGSWGFDRANSVGLPGGHGEEIVRSFCFYDDEQVVFTAGEDGNIKAWRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYX0</accession>
    <name>A0AAD9CYX0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_569664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368929.1">
        <property type="nucleotide sequence ID" value="XM_060504219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYX0"/>
    <dbReference type="GeneID" id="85388118"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09394">
        <property type="entry name" value="LIM1_Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09395">
        <property type="entry name" value="LIM2_Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000044">
        <property type="entry name" value="Rho GTPase activator Rga"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF4">
        <property type="entry name" value="PROTEIN ESPINAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1728874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="489" mass="53245" checksum="85EC5DD8F556801C" modified="2024-05-29" version="1">MTAVVEDYLESPMDNDDVFPCKGCGEILEEGKAFELAGNRWHLNCFRCNTCGTLLDSDANLLLLGDGSLICNNCTYSCSACNNKIEDLAILTGDQAFCATCFRCRNCKRKIENLRYARTSQGIFCMSCHESLMARRRKKSKAAAQAKSKEKDGSPMITDKSLPALPPNAIPPNAFHDTKVDPDSDKETPTELSPRPRPAYGRNDSSSKSSTRPSRSPERVSEPTRESGLGLPAANYRNNRNSTMYAPNNNADTNGGDDGFFIPVALDNNPASNATPRSTSENVSSASKKDKDYFSVPRASTDKKGESQSSTPHIAFQEKGRQPSSDYESGPIKLPLRKTSKSSRHDGRSSVINDEKSQKVTTGKLSPSIDEFKLQDAPKSKKLISPRSASHSAALTPESGSAKSSEGVLRKDKEPFPNLPSSDSPPRMARSSQDSRQRDESDVRPSMDSISSSRTDTTAGKSIARKELPSRNCKSISHSCFTIMQGAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZ08</accession>
    <name>A0AAD9CZ08_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ETC complex I subunit conserved region-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_606572</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369122.1">
        <property type="nucleotide sequence ID" value="XM_060507389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZ08"/>
    <dbReference type="GeneID" id="85391288"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1729067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="242" mass="27385" checksum="9AF384C2CEC16717" modified="2024-05-29" version="1">MRRTLRLLAGVKPARYLEAGTPTGLTGLWTHNSPRSTLLYLYGTTLEKLQTVPESSLYRQSVEAITKHRLSLVEATVPPGYPEWEKRAEQIVKEKPEQFRLVSGRVDGSGARTVKLGGRTFVVATQHEEQDVRYEEWDGEKDEGGTLEGPRSEAERKDHQLLADRKDLNDIAKVQWEAEPQLTADQISELETKIGAGLIEEVIQVAEGELKLVDVMTQAKVWEDLEEKPVEGQWTYFERKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D222</accession>
    <name>A0AAD9D222_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_747585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370430.1">
        <property type="nucleotide sequence ID" value="XM_060513460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D222"/>
    <dbReference type="GeneID" id="85397358"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1730375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="34567" checksum="58C8ADC91A941F73" modified="2024-05-29" version="1">MTSKTPKILIVGATGQTGSATIAALASTPSPPQILALTRSPSSPKSQALLSLFTDRRATTTTVTPSAITLIQGTPENPSPIFASHPDISALYLVTVPPGDEAQAIPLIDAAVSHKVPHIVFSSVDRGGDERSWTNPTPVPHFAAKHRVEVYLRDKTRGTPTKWTILRPAGFMDNYRAEAGLMGSVMGGLWATMPAGGKKMQLVSARDIGLFAARALVEGPGTEAEGGGWGGRAVGLAGDEIGFDEAEEVFKRVVGQRMPRTWGVVGQGVRWAFEDAGRSMEWFEEEGYKADVEELRAMEPRLQTWETWLRESSGWVKDDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2W5</accession>
    <name>A0AAD9D2W5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_1643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371763.1">
        <property type="nucleotide sequence ID" value="XM_060501419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2W5"/>
    <dbReference type="GeneID" id="85385318"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="207" mass="23115" checksum="FC492CD8F51CD357" modified="2024-05-29" version="1">MKWLNHRLGHVQGLAPFAPGQSGLHIEALFRQERVTRYGSGTFFQAVSAQLLRSWSWTVMGSMRFVSWRHGRAVQPLVGSFKISGCLSSDSGVLLFPKSTLHAISSPVHLVRCAQDHRQPFPLSPHAPQPRVVLTMITGEVLGSSTPIPRSAYRICLGYTGGHAVDSRMKDPDLQEQRRRRHRGLQQTTSGVHLSPWIPSKPRPSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3N2</accession>
    <name>A0AAD9D3N2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371930.1">
        <property type="nucleotide sequence ID" value="XM_060515144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3N2"/>
    <dbReference type="GeneID" id="85399042"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="230" mass="24529" checksum="ABDB79AA5D52D826" modified="2024-05-29" version="1">MSTEFVAPIGRHCLITPLVASVTVPDAVMGVHIDDLGPNQANTASSSPGILVCVALRILMHFERFRSLGSRGQLVSGKRPTGYARKQVSTAKHRLLGLGTANCPGPSSSKSTHSGGKPVSNQPRINDILLLGRGDKLSGRDSLHLHAKPCYGFESPDQMCPHKAPKHAETDSDLAARHVSFSSEISSGQWFDDACRGCTVQIRDSTVHCNQRSPTPPPLDEDLLAIPGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U475</accession>
    <name>A0AAD8U475_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid permease-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_595878</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000334">
        <property type="protein sequence ID" value="KAK1701833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357062.1">
        <property type="nucleotide sequence ID" value="XM_060506826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U475"/>
    <dbReference type="GeneID" id="85390725"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF6">
        <property type="entry name" value="AMINO ACID TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1701833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="23648" checksum="768DDCFE9BD07BB9" modified="2024-05-29" version="1" fragment="single">YCATRALYSLSLEGRAPRFLRRCNKNGTPIYCFAIVMLFPMLSFLQVSSSSAVVITWLTALITGGGLISFIIMSITFINYHKACVVQGVDRKTRPYYGYFQPYGAYIALGFQLLILLVYGYYAFRPWSVELFFQSYTMQILAIVLFCGWKLFKKTRYIRPHEVDLIWERPLIEAYEDSLVDPPVGFWTEMAQMVGFRRNKVGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U4E3</accession>
    <name>A0AAD8U4E3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_645232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000304">
        <property type="protein sequence ID" value="KAK1702627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357167.1">
        <property type="nucleotide sequence ID" value="XM_060509826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U4E3"/>
    <dbReference type="GeneID" id="85393725"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042260581" evidence="1">
        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="103" mass="11623" checksum="8A58A44DD9A36AD3" modified="2024-05-29" version="1">MYTRIERLCVIVASILGSVFALRIDPASAQNVTKRLGDGGRETDLLKNVILFTNISKANNASMVAKIGKPGFIYRRPYEYIMSQRVPWELGKQPASSKQNHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U611</accession>
    <name>A0AAD8U611_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipase B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_642970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000212">
        <property type="protein sequence ID" value="KAK1707329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358017.1">
        <property type="nucleotide sequence ID" value="XM_060509649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U611"/>
    <dbReference type="GeneID" id="85393548"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053228">
        <property type="entry name" value="Stereospecific_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37574:SF1">
        <property type="entry name" value="LIPASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041905192" description="Lipase B" evidence="1">
        <location>
            <begin position="21"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="469" mass="49275" checksum="70E166D87DAF3BA3" modified="2024-05-29" version="1">MRSQIQQLVLAAALLQSADAAPAGLLDGLGVVTQLLALPTDYVSSLTGVLGTKPGSGVGAGVLNVGDLQTKLGSIWNTGSTGDFYGKLQKQIGQGLVPNNLLSSFQGLLGTGLLGSLDLANNANKLIAPLNSIDSTSNNNPVNPAKPVYPKKDASDAPYTLSEQQLRQAIYIPQTFTYGQKPPVIFIPGTGVYGGETFSPNLLKLLTNVPYADPVWLNIPGALLGDAQVNSEYVAYAINYINGISNKNSSIISWSQGGLDTQWAFTFWPSTRNAVANFFPVSPDFHGTVLANVLCLSPGNGALNAPCDPSVIQQQYTSVFINTLRSRGGADAYVPTTTFYSAVLDEVVEPQQGTAASAYLTDARRVGVTNIEVQSVCPGRPAGSIYGHATMLFNPLTTALIKDVLQRGSGPAKISNINLNDVCKDFIAPGLNLEDGIATAGSIVAAGIRLLAYLPKLIAEPTLMAYARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9T3</accession>
    <name>A0AAD8U9T3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_643353</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000221">
        <property type="protein sequence ID" value="KAK1706771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357899.1">
        <property type="nucleotide sequence ID" value="XM_060509666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9T3"/>
    <dbReference type="GeneID" id="85393565"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="71"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1706771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="661" mass="74627" checksum="8F99CE5FF1FDF285" modified="2024-05-29" version="1">MNNLSFTQTMPQGHQASAHVEGARQSRILPLLPHPSTIQPTNQDLELPFNDPGDTSHPKRKRASRPKVRSGCITCKIRRVKCDERKPTCFRCEKADVGCDGYSKEDADSKRSAEQRRLAVAAQDAQASRQLLPRPNESGPVAAGQGIAARVPVPPPLYPSTLRINQEDVHYYDLFRHRLVRDLWGSGHSDAWSRIVLQESSDDPCVQESLLAIGAISQAQMLEEMSKDQLDAMPSALRPWGTKIAPSGGLLNHHHRSALLHHVKAVSIYRQRIQDPSSTSPRSVIIMTLLLVGFEFIQGNMNNVDTLTGTGMRLLENRISLTQRPPRHANGNGDTSIETPQPVANQLRRGVRYDEMEDIEHLLPCLSLMSGFTHFFNSHRTAMPMMNGTPILELPEPGVTVVAKLEVFWGQFFTRAVVHIMRSLHDQLRYKQRNITQAALEQATFLSYIRMWDSVLEVYLKDPSLEDNARRALRKIQIHRLLIHIVISCGLDRTDMCYDAFEADFRDLLNRIVTYMRDPGPIPKVGFTFTEGLTTPLATIVAKCRNHELRMQAVHLLNTMAWRESAWDGKALVIGKSGVVMLEERGMDANGFIPSGSRWVWMSGKWDLEKRELVATYLRLMPNEDGLPVHAHLELDMDNLLDTCSMVGCHGRHDPFQCYQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA38</accession>
    <name>A0AAD8UA38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynamin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_539299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000123">
        <property type="protein sequence ID" value="KAK1715457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360256.1">
        <property type="nucleotide sequence ID" value="XM_060503386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA38"/>
    <dbReference type="GeneID" id="85387285"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001425">
        <property type="entry name" value="Dynamin GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF66">
        <property type="entry name" value="INTERFERON-INDUCED GTP-BINDING PROTEIN MX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="4">
        <location>
            <begin position="35"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="3">
        <location>
            <begin position="577"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1715457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="679" mass="77266" checksum="926604653FAA8BE5" modified="2024-05-29" version="1" fragment="single">MAPNIDSALGTADMANEQRGLLELIDKLQFAQLDNVKLPQIVVVGDQSAGKSSVLEAITGTPFPRDAGACTRFATEIRLRRSAEASLNVSIIPDKNKPFRDQERLKQFGGAVDTDMSFESLMRSAVEMIAPKNIPGRFAARDILVVEKRGPDMPLLTLVDLPGLVKNANNDQSMDDIKTIETLCERYMKSSRTIILAVVGGNTDYVQAPILTKARHFDPSGSRTIGVLTKPDLCESIGLEDKFIELVQNRDKQNYFKLGWYVLLNPGPRDQGQPWPSARERRQREEEFFGRGKWRALPSSMCGANALKQKLSVQLQRHIGRHVKTLRKQIQKALDDCDSELKSMGTGKDTVEEMRIELVELFSSSKELVIPAVYGFYKNPPRKNFFRATADPRGTPAQNLRARAIEENEKFSHRIRQNGRKFGFSSSTAPGTADGVTISDSSKREFVGREVEMLLRQIRGSEFPMDPKPRAVYMLFQSYSENWPKLAQEHKDNLGVVCNEFLSEVIDFAWPQRMREPLRYQFLDVQMKKLLADAQVELEHLTQDMNLEIQPYDPEYEERLRKWQIETTKDGATYTEAQEVCEKMLIFYELAAKTFIRNTITQVVERHLLQGMYSIFNSVEILGMPAETVEAIAAENKETRDRRMTLKTQKTAIEEARDICASLAMRKELRMYADEDRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB10</accession>
    <name>A0AAD8UB10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_745371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000196">
        <property type="protein sequence ID" value="KAK1708403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358281.1">
        <property type="nucleotide sequence ID" value="XM_060513188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB10"/>
    <dbReference type="GeneID" id="85397086"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF3">
        <property type="entry name" value="HEXOSE TRANSPORTER PROTEIN (AFU_ORTHOLOGUE AFUA_8G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="38"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1708403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56248" checksum="CD6C477D32751E95" modified="2024-05-29" version="1">MGHVKEANAKAVGAELAAVLPDIGPWYKQPHILRLNLCIASLIMCASANGYDGSMMNGLLALPQWHAFMKQPTGAWLGFVNAAYSLGNVLVYPIAAWVCNKYGRKMGIYVSWVCLGTGSVLQTAAPNDAAFVCARFLIGCASGFFLSAPLLITENAYPTHRGMVSALYNCGWYFGAVVAAWATYGTRNLDHWAWRLPSLLQVTLPVLSIPGLLFIGESPRWLVSVDRTDEARAIIARNHAGGDTHSPLVNFEMMEIEDTIRAEKEAHSETKWSDLWATPGNRHRLFISVSLGVFAQWCGVGVVSYYLAMVLSSVGITSVDDQTLISACIQIWNLICASTAAIMVDRAGRRGLFLASGTIMLISFSIVTGLSGSFANTGNAPTGTAVIPFLFIFYLGYDIALTPLMVSYPVEIWPYRLRAKGLTVALMVSIGCVFFNTFVNPIALEAIEWKYYFVFLAVLVIMLISVWFYYPETRGRTLENMAYLFDGESAEVGTGNASSALKEAEASHVEVTHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBD8</accession>
    <name>A0AAD8UBD8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Family 2 glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_757857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000187">
        <property type="protein sequence ID" value="KAK1709119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358458.1">
        <property type="nucleotide sequence ID" value="XM_060514953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBD8"/>
    <dbReference type="GeneID" id="85398851"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1709119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="400" mass="45844" checksum="D92C11C547D13981" modified="2024-05-29" version="1">MSEYVLGVMWAWYAYDEVLTKKLMQKVEPIPLPQEPSFKSTDVSIIVATINTPDTFTDCLRLWLANKPKEIIIVTIDRDLQRVHDLVKPVIIEGDDRISVMTADYASKRYQMVVGIKEAKGKILALVDDDAFWGTLETLPYLLAGFEDPKVGGVTGKQSALISSDRRNPAIITPWEVASLRSLDNQNNVQAVRSAADGGCWCMVGRTMMVRTDLAQDPRFMEAITNDRWNGQLMNTGDDVFLTRWLQTEGWDIAVQNAPQAEITTLVMRDSGLLHQMIRWQRNAIQSFLTTVIYQPGIRKIKQKHPYMARKMIERLLRPVIAWVHIIAFMMCIAKKSPIAYFVAGYYIWGWFRTYNAFARRFPFTSRQIWACFLLDNANPILDVYAWLTLSTEAWGTRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBI4</accession>
    <name>A0AAD8UBI4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_537710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359728.1">
        <property type="nucleotide sequence ID" value="XM_060503375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBI4"/>
    <dbReference type="GeneID" id="85387274"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33148" checksum="8832898CB9A5D42D" modified="2024-05-29" version="1" fragment="single">RSHTLDPDGDVVLVLENANPAFALWDQCTTAGLQELNLCPVSTVSCVEFIVSSRHLTFSSHYFKAQLCGPWAEASVHSQDGRRHTQIRDWDADALLILLQIFHAKTGDTPRLIDLELLAKIAVLVDYLSCYNTVRFFSTLWIDALKEQLPSQCNRELLLWLFVAVVFRRDDIFQTITKTAVTESKGPLPTLGLPFRVDLIGLCSCRTVYIPLLIVADQIDFRRQDAIAGILGTLETLGTSLLRGLTGCDFGCSSALFGALAKEMAKHNLMDPEPCAPFLGYSITALEKATKDFQTPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBJ2</accession>
    <name>A0AAD8UBJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Threonine dehydratase</fullName>
            <ecNumber evidence="14">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_744468</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000137">
        <property type="protein sequence ID" value="KAK1713417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359743.1">
        <property type="nucleotide sequence ID" value="XM_060513159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBJ2"/>
    <dbReference type="GeneID" id="85397057"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04906">
        <property type="entry name" value="ACT_ThrD-I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04907">
        <property type="entry name" value="ACT_ThrD-I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1020.10:FF:000001">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000008">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000005">
        <property type="entry name" value="Threonine dehydratase catabolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="16">
        <location>
            <begin position="402"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="16">
        <location>
            <begin position="500"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1713417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="581" mass="63255" checksum="69ECC7C2B3767433" modified="2024-05-29" version="1">MSENAEPPVVAVMTNGTLNGVNGDHQPRPRTPQPAGMSLTEYSANPSTPPEERRSRIKGVVPEDFLLPDGHPDYLRMIAAATSRVYEACKVTPLQPAVNLSNRLECNVLLKREDQQPVFSFKLRGAYNKMAHLDPAVSWKGVVCCSAGNHAQGVAYSARKLKIPATIVMPEATPSIKHLNVARLGGHVVLHGADFDAAKEECGRRAAQDGLINIPPFDDPYVIAGQGTIGMELFGQINMSKLDAIFCCVGGGGLISGIGVYVKRMAPHVKIIGVETYDANALVQSLAKGERVVLDSVGLFADGAAVKTVGEETFRLCKDVVDEVIQVTTDEVCAAIKDMYDDTRAGLEPAGALSIAGLKKYVAQNPSDRRKTMVAVTSGANMNFDRLRFVAERATLGEGKEALLAVSIPEKPGAFSNLITSIMPHSVTEFSYRYATDEVANVLIGISLTAPASQRTQELQMLLERIRSHDMSVTDLSGDELAKSHIRYLVGGRSNVPNERLYMFNFPERPGALEKFLMTLRPKFNISLFNYRNYGGDTGKILAGILCPDNEVDQLETFLTEIGYPWEDCTQSAVFKTFLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCC2</accession>
    <name>A0AAD8UCC2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_585072</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361572.1">
        <property type="nucleotide sequence ID" value="XM_060505819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCC2"/>
    <dbReference type="GeneID" id="85389718"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="46"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="306"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1719488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="408" mass="44786" checksum="42898B9D0D017AFE" modified="2024-05-29" version="1">MSGLVLAAEGETTHNVTAEYLAEDSGGTLIGISIAFAVLTTFFLGLRLFAKRFTAGGYGLDDYFLAAAYVVDLGMCAVGIVMVKVGGVGRHVEFVEEFHPALLTGWAKCILAFEIIYFTSVALPKMGIVCLYLRVFNWKGAMRTTAYVLLATLAATSFSFIITACFQCQPIEFWWDRTIPGGKCVDVQAFFHAQSIPGFVLDFFIMTLPLKTIWDLKLPTHKRIALIGIFMIGSFGIVASIIRAVIFFSNSAFSDRTWASVGLVGWSIIETGTYIIAACLPHLRPMISHYTPPWLKSMVRKTISQASNSMSKVTNSKTHTQPRRGDDEVELTARSKKQTVDTESDMGGDEERGYAGGIRSPASGMTVEVRKSDDLVGGEWARQGQIRVTTEVKMERVRTSAFLKGPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCS7</accession>
    <name>A0AAD8UCS7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7053 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_589972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359445.1">
        <property type="nucleotide sequence ID" value="XM_060506286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCS7"/>
    <dbReference type="GeneID" id="85390185"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055481">
        <property type="entry name" value="DUF7053"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38117:SF2">
        <property type="entry name" value="NACHT AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23155">
        <property type="entry name" value="DUF7053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7053" evidence="2">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="420" mass="46320" checksum="4480964CF924C50E" modified="2024-05-29" version="1">MLRKKEVYTTVTPIPGFIPRQLAIDILHSHSEVITLNPLVLDHKPIKAPRDAASDEYYSTWYEITERIQYIPGIGKMGSGKISFNGCFHDMPWGLQTHTYAPMNIDIRIKYKIDGNQPGVEPPQPPEIGMSGLGVPADGLYLREDIEIRCNITMVNFVKAQLKAASKEMVSRIIKKAELLDAGVLQAMITDGKLKTINPADRTSTGMSGAHSPLFNQRPEGSPRPESYSPTTPYQVPRPVSMQQFRPGSQGSYGAHQNQPSELYSQHSAPQTSFIAELPGNFYHPQQSSNNLQPPQPSPGLQGGDRDSMSQQSQLSPDPNSWRWSQGQPSPSQQSSRPTSMASSEASSGYASPALDHKGFSSELPTHPETQEEHRGDAHAKAAEAAQQQQQQHRVKGPQAYPTYGQAYTYNPADYAPMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD64</accession>
    <name>A0AAD8UD64_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_591944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000181">
        <property type="protein sequence ID" value="KAK1709461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358595.1">
        <property type="nucleotide sequence ID" value="XM_060506492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD64"/>
    <dbReference type="GeneID" id="85390391"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF213">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042275092" evidence="3">
        <location>
            <begin position="22"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1709461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="662" mass="70728" checksum="0C2A70B2DD67CEAD" modified="2024-05-29" version="1">MRWCLHVTNVVLGYIVATASAVPSQHFVPRQSTDILASYDYVVVGSGPGGGPLAARLAIAGKKVLLIDAGDDQGDSIPYQVPALNLQSTEYAPMKWDYYVQHFADLEAQKKDSKMTYRQANGELYVGLNPPAGAEPLGILYPRAGTLGGCGSHNALITVYPHKSDWDGIATLTGDTTWGASNMRKYFQRLENAEYLPNGIVGHGFDGWLTTSVTDLGLVIKDIKLLTVILSAASAMGKSLLGLIFSTIQGLGEVLLRDLNVDLPSRDSAEGLYQVPISVNKGVRNGPREFVLDTANAKNADGSRKYHLDIKLTTLVTKVRFDQSGAKPRAVGVDFVTGQSLYRADPRSGDAGSGVAGSVNATAEVIISAGAFNTPQLLKLSGVGPKVELSSFGIPSIVDLPGVGTNLQDRYETSVIGETPTDFQIIEGCTFIRPGTDDPCLKKWQDGAASGDRGIYGSNGISLGIVKKSTVAEGDPDLFIAGAPVAFPGYYPGYSVDGTADQRHWTWITLKAHSRNRAGTVKLRSADPRDMPQIDFNSFQDEATGAKDIQAVVEGMKLSRKMFESVVPLTGGFTEVWPGKNVTDADLPEFVRNEAWGHHASCTCPIGKDGDATAVLDSNFKVRGTEGLRVVDASVFPKIPGYYIASAVYMISEKAADVILGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDL5</accession>
    <name>A0AAD8UDL5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_637911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000141">
        <property type="protein sequence ID" value="KAK1713012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359628.1">
        <property type="nucleotide sequence ID" value="XM_060509337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDL5"/>
    <dbReference type="GeneID" id="85393236"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF40">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1713012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="688" mass="77281" checksum="60C6742747DB80A1" modified="2024-05-29" version="1">MDSFHHKQHTASILSYDGTYESNMKSKMNVRLAACEPCRRSKLACGHERPACTRCTGRGQRSHCVYRSRPFRRRVTRTQVQETESLMSVGPTETIATVTSSTPQSPADAPSPSTGTPTASTQPYRYPNPGFLGVSSHSTIFNHVFSGDGFRPPSDADLTPQPSLASPIDLVGNQVVMDKAMHALSRLEKMDISKVTPLVRSWLERGVNLPLAGPIVIECLWSLEHWREVLTPTTDISGESGGSSSGITSAGYVATLLTNTLRPFALSSHSTRQDFLAQMVGSSLRWETLGIFFRRRLMQALTYIGDYCLETSLSLDCLNDLQLILQYENFIVHSHLDGDQSYHSWRRIGDLASSLFALGYHEKIERCNPNLPSFIIELRKACFCRIYTADKGLAVFLGRPPRIVKDYCQFQIPKVHNGWIEDEVDVRVAHLEPINYNADTRCVARFALLKEEVLQLLRRKNMTDVTKNIREFREKVEALWQNLPGHFRLGSSLRECQQSPFGRDFLAHIRLDYLHNLFLLGLVSQQPISEPNDELLKVAIEMLSIVVEVILLRDQLVNSGTCLIWKVAQYGLPAAGVISLALLKENAASDVFLHSRSKMIQDLSVLVAETRTGAWIQAGEPNFALFTRATGTIQTMLDSLLATRPSAEQVQTTNVTTLEVWEPYSNHQLWDFEMEFWSNLAEHPTLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDN1</accession>
    <name>A0AAD8UDN1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Cytochrome P450</fullName>
                <ecNumber evidence="14">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="14">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_710049</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="14">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="14"/>
    <dbReference type="EC" id="1.6.2.4" evidence="14"/>
    <dbReference type="EMBL" id="JAHMHS010000145">
        <property type="protein sequence ID" value="KAK1712622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359479.1">
        <property type="nucleotide sequence ID" value="XM_060511582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDN1"/>
    <dbReference type="GeneID" id="85395480"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 14" id="KW-0288">FMN</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="12 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0521">NADP</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="16">
        <location>
            <begin position="507"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="17">
        <location>
            <begin position="682"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1712622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1066" mass="117319" checksum="FCCEF747816553E6" modified="2024-05-29" version="1">MDIGIDEESTKLSLGIEVPIPGPKPLPILGNILDIDLVSPLDSLIRLVGKYGPIFSLTFAGTREITVSSRELVNEVSDEDRFCKIVTSGVETMRAAAGDGLFTAQHNNHTWGVAHRILMPVFGPLKIRSMFDDMNDLSEQLCLKWARHCHSAPIEVADDFTPLTLDTISLCAMDYRFNSFYLDKKAHPFVESMVEVLAEADLQAVLPDVFSLLRPRAMSKFRNNIEQMQATCRDIIAQRRRANGKKMPNDLLDAMLNGKDPETGDSLSEEAIVHNIITFLVAGHETTSGLLSFAIYYLVEHPQELKKAREEVDRVVGHGPINVDHLQQLPFLDSVFRETLRLMPTAPGYYVTPFKDEIIGGKYLVKPGEALCILLHTLHRDPKVWGSDAEDFRPDRMRTLEGIPQNAWKPFGNGMRGCIGRAFAWQEAQLVISMILRNFDLSKGDPDYKLKVKHLLTIKPANFKVRVSLRNDKRPTDFLKSLRTISEPIPKLIVNPMVISPSLLGPITILFGSDTGTCEAVAQRIAVEAGPKGYSPIVLTMNDAVDRLPQNQPVILVSASYNGLPSRNAAKFVPWVQGLKPGDLQHLKYAVFGCGHRDWPATLFKVPRSLDSILETAGGQRLCTLGVADTAATDVFFEVEKWLTNDLWPILLGYSATRATRPKSDVDVKLTLEDPPRLALRSGFVAATVKDIRALSAEGVPAKRHLELELPLGTAYQAGGHVHILPVNDAQLVRRALSYFRLSGDVVLTIKSESGRPLPVPSNTPLTAWDLFASYVELTGTATPGNIQVMSELAVSDETRRVLEVMSKSLLGSEPRSRGLSVLEVLESYPDLNLPLSEFLIMLPRMRPRTYSFSSSPAWQSNSATLTYTVEKKGVASNYLASLRPGSVFFVSPLPSTPQFCLPSAATQATTPVIMIAAGAGLAPFRGFIQDRAISLRSGATLAPALLFFGCHGKLLDDMYRDELDGFEAENAVKVFRAFSRDGDMSCKHVTDQLRNHLGEVSALWEAGANFYVCGGKKISDSVFDILTPTLFKNEKNTGKGAGAADNVQKSSSMASSSRYVVDVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE78</accession>
    <name>A0AAD8UE78_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin-nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000127">
        <property type="protein sequence ID" value="KAK1714976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360119.1">
        <property type="nucleotide sequence ID" value="XM_060514748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE78"/>
    <dbReference type="GeneID" id="85398646"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071">
        <property type="entry name" value="5-NITROIMIDAZOLE ANTIBIOTICS RESISTANCE PROTEIN, NIMA-FAMILY-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071:SF2">
        <property type="entry name" value="FLAVIN-NUCLEOTIDE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="280" mass="30264" checksum="8320051F3518B8C8" modified="2024-05-29" version="1">MPRTELEYPKEPYGTVKRYSPRASYALRTIHTIINTSTILHVSFNDPQSPFPTILPMLGQMGSFSRPSADEGDVLDLYLHGYVSSRLINISRQPSNTSSASDAPPSSPPGLPVCIAASHLDGLVLALTPNAHSYNYRSAVLFGHATLVSDPSERLYAMQLITDGVVPGRWEGSRVPPNKGELSSTSVLKVRIATGSAKIREGPPGDDRADKEDKSVTGRVWTGVVPVYQVLGEPVAGPYNEVTEVPGYLGEYVRETNAVTKEAAFEAARKIVVKKGGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEP1</accession>
    <name>A0AAD8UEP1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline rich protein 5MeD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1715996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360390.1">
        <property type="nucleotide sequence ID" value="XM_060506076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEP1"/>
    <dbReference type="GeneID" id="85389975"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054215">
        <property type="entry name" value="DUF6923"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21959">
        <property type="entry name" value="DUF6923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6923" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="211" mass="22210" checksum="F99FB159C8DB19E6" modified="2024-05-29" version="1" fragment="single">LGYNAREDYLYGISQNEAATDFKIIRILANGTGTYVATVSKLTTGLFNSGDIDENGQYWISTGGADFYQYNFAPGTANYGGLVNSGKLSGTGGYTIGDWTVVPGVGGGDLWSVGVSNQVAYLLRWSRTTHAFTVVRNLGNLTGATGTTVPFWGASYATTDGYLFAVENGSGQIWRIAVDGSSNPLRLKDAPVSSRNDGARCLDSGAIVVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UES5</accession>
    <name>A0AAD8UES5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tat pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_584961</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361652.1">
        <property type="nucleotide sequence ID" value="XM_060505810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UES5"/>
    <dbReference type="GeneID" id="85389709"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="55"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="601" mass="65730" checksum="6BE6E000785F6212" modified="2024-05-29" version="1">MTSAYANGSAKAAYSTSSATTTALSRWSIATTQLPVVDKIKALHIYDFDNTLFKTPLPNPALWSGPTIGVLSSQDVICNGGWWHDSRILSATGEGADTEEKRAWEGWWNEKIVELVKLSVKQKDALCVLLTGRSERGFGELIKRMIHSKGLEFDMVGLKPAVSPTNQNFSSTMHFKQLFLTAVMETYKNAEEIRIYEDRPKHVKGFRDFMTEYNRKQNINATRTRGPITAEVVQVADMSTTLDPVVEVAEVQHMINLHNEEIGKQSSDVRPQRLRIKKTVYFTGYLISKEDTAQLMKMAQIPSGLPEQELKFHANNILICPRPCPASILEKVGGMGSKMKWEVTGTACFENSIWAASLRPVPATAKFHTDNPSPLVVLALRKGARPVDAGKIQNWQPIPADKAMTFETTVGEKMILRIEPEDPREDEYESLFANKSSKRKHDGGDYSRDHHRHNPYNGRNERRDFHSGRGGGGRGGGGGGFRGGGGRGGRGRGNGKGGRGGRGMHGYRSLDDVEPRNQQGGYGQTVEYDDNSYPSLPAQQQGSFQGGQQQQYQPPLSAWNSGPPPNAPTGPAGRPMGGGGGGGNYGGGGGGGNSNDLQNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFT1</accession>
    <name>A0AAD8UFT1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">OPT family small oligopeptide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_755847</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360783.1">
        <property type="nucleotide sequence ID" value="XM_060514674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFT1"/>
    <dbReference type="GeneID" id="85398572"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="627"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="707"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="770" mass="86263" checksum="866E4B3CFBB59306" modified="2024-05-29" version="1">MSGTTDQHGEKTAVASPRPQLRPDEEARDVENLDKAMAYAIDEIEEHFNIESDNSPYPEVRANVPNTDDPSMPVNTLRMWVLGVVFTMVGSGINQFFSMRYPGVTISSLVAQLIAYPVGCAVARILPVKKVRIFGRWDLVINPDHYFNIKEHAVITIMSNLSFGPSWATDIIQAQKASAFYGLDTPVAYQFLLGLSMQLFGLGMAGLAYRFIVEPPHMIWPSTLANAALFQTLHGRANPLADGWRITRYRFFLYVFIGGFFWYWLPGYLFTGLSTFAFVCWAVPNNVVVNNLFGMSTGLAYLPITFDWSQIAYNGSPLVVPFWAQANVFAGWVILFALVTPILYYTNTWYTAFLPFSGADTYDNTGKIYNATRVVGKDGNFIVEEYEKYSPLFMPVTFALSYGISFATMTCVPTYIFINYYKDIIGAFNPSRKKDIHTRLIEKYPDTPWWWYGIMTAAVLALTIIVQEVYKTQMPVWGVFVAFGLALIYLIPTGSVYAVANLNSNVLTVLGEIISGYAIPGKPIVMLIFKFYAYTGLSQAMIFSSDMKLGLYMKIPRRTLFVAQLAACITGSLTQNAVLLWMLNHVKDICHESQPNGYTCPQGRVNFSSSIVWGAIGPARLYSVGKIYSGLLHLFWIGALLPVVTFFLKKRFPENKFLRYLHWPLFFAGTGNVPPATGINYTSAFVVSFIFNKWLKGKFPQWWAKYNYVLSAALDSGLAISAIVIFFALVFPGVQLSWWGNNIQRSTIDGQGVPLKAVPLNGTFGPATWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFU7</accession>
    <name>A0AAD8UFU7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 6B homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_755730</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360929.1">
        <property type="nucleotide sequence ID" value="XM_060514658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFU7"/>
    <dbReference type="GeneID" id="85398556"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000020">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000049">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000033">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="198"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1717442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="421" mass="46989" checksum="51DA9DB0312EAB48" modified="2024-05-29" version="1">MGDVLVENPANQVAPHKKTAPSTIPSIENFEGIATEGGDDYATLKKLQRQLEYIQLQEEYIKDEQRSLKRELVRAQEEIKRIQSVPLVIGQFMEAIDQNTGIVQSSTGSNYVVRILSTLDREKLKPSSSVALHRHSNALVDILPPEADSSIAMLGADEKPDVTYADVGGLDMQKQEIREAVELPLTHFDLYKQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTTANFIRVVGSEFVQKYLGEGPRMVRDVFRMARENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTANVKVIMATNRADTLDPALLRPGRLDRKIEFPSLRDRRERRLIFSTIASKMSLAPEVDMDSLIVRNDPLSGAVIAAIMQEAGLRAVRKNRYNIIQSDLEDAYSSQVKGTSDENKFDFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGF9</accession>
    <name>A0AAD8UGF9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4 9">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_755382</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4 9"/>
    <dbReference type="EMBL" id="JAHMHS010000099">
        <property type="protein sequence ID" value="KAK1718820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361320.1">
        <property type="nucleotide sequence ID" value="XM_060514602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGF9"/>
    <dbReference type="GeneID" id="85398500"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000005">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000001">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1718820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="24272" checksum="0A644A56B6E68FF5" modified="2024-05-29" version="1">MSTTSHPPRWAALARDTNETKIQMALNLDGGAFPPDTDERLTAAVTEHASQASKSQTISVNTGIGFLDHMLHALSKHAGWSLAIACKGDLHIDDHHTAEDVCIALGYAFAAALGSATGLARFGYAYAPLDEALSRAVVDLSNRPYSVVELGLRREKIGDLSCEMIPHCLQSFAQGARITLHVDCLRGENDHHRAESAFKALAVAVKMATSRVAGKEGEVPSTKGTLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGN7</accession>
    <name>A0AAD8UGN7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_582869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362582.1">
        <property type="nucleotide sequence ID" value="XM_060505594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGN7"/>
    <dbReference type="GeneID" id="85389493"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20273">
        <property type="entry name" value="Complex1_LYR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046896">
        <property type="entry name" value="Cup1-like_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="378" mass="43726" checksum="23F8BD2CD55F66E0" modified="2024-05-29" version="1">MPSHFVPAQNSRHRIAAIALYRALVREARAVPLPNDVLRKGVENPLPRLVKKGFKRNQTEASYRLVLAALSKGYKFLNLFKGAQTPSSKEHSEILTYLREKSLRDARSEAGKPPPLPPKIERPKPKWPPLLKRISPLDEPPVYISERHPVPREELSGIRHVPNVAVTAHGVVFLRQGKPQHRSVCDYVQKKNKYKIKNMDHLLASMRDEQQFAKEEDQWDGHLQSEIKSQKRVVERLVRLRQRIEQPLADLPDWVEKPGFERVGTLEPYVYEESYTSSVAATYDDASKRLSDDAADQSARARAFLEIREAEKKALEEDNEYYREKGYKWMIDTPYKKKQRRVAKRKKGGQDRFERRAVRQDKARKSNFVGLSPAPIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGU0</accession>
    <name>A0AAD8UGU0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase epsilon subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA polymerase II subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_632754</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361281.1">
        <property type="nucleotide sequence ID" value="XM_060508994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGU0"/>
    <dbReference type="GeneID" id="85392893"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="7">
        <location>
            <begin position="111"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="27"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1718781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="34449" checksum="A43A69AF450FA5F2" modified="2024-05-29" version="1">MPPRKSDASRRSDVSNARFIVMDEEPSASSTPAKAAAAPAAAATAAGTPSSASAAKPSSATPSSVPAPTPDYAAAAAAAKSTPATTEKKESQTHDKMAKADRDALTIEDLSLPKSIITRLAKGVLPPQTQIQANAVLAMGKSATVFINYLASHANEITTNAGKKTVSAEDVFKALDDIEFGFLREPLEQEFAKYTQIQNAKRTNYRNKVAAKKGGAAAGAAGTASADASLLSNPDDSVMTAASSDTAPRSKKARVDDSAMTVDEEADDAETEPEEEAEEEEDEEADEEEEEEDDDEDEEGSSEEMHDALETKEGEGSDVDEALDGDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGU6</accession>
    <name>A0AAD8UGU6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pantothenate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_706857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361084.1">
        <property type="nucleotide sequence ID" value="XM_060511533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGU6"/>
    <dbReference type="GeneID" id="85395431"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF43">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1718084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="487" mass="54896" checksum="2F20033885418D08" modified="2024-05-29" version="1">MTSDGRKQDFEVSTDPEVQLASSEVGRWRVLSNISRKIWGDDPRERKYVRKLDTFLFSYVLLGYFIKYLDQNNYSNAFVSGMQEELDLYGNERNLLNTYFNIGIILGTIPAQMIQLKYVRPSIWIPACELGWSALTMIMASARNVETLYALRFFIGLLESCSFPGFASILGSWYGKSQLAKRMALFEQTAAIAGMFSGYLQAGLFTGMNGTAGLSGWRWLFIMDGVISIPIALYGFFALPDLPHNTRAFYLQKEDREYGMERIKAMGRISPSKLTLKAIKEIYTSWQLWAFILPYLMVAEAGSGTGYFNLFLKSEGYSVVKTNILPTIGNAIQIVAAFAMGWLSDVTGSRVMTVIFVQVMVLVSNIMLSIWNVPKAALFAAFYLSYTGGAAQPIVISYGHEITQSNANLRQLLVATGNIFTYTFSAWMPVVLFPTYDAPKYRYGYQILILFGGLAVGGMYLLDFLYKRDLWVRILGNETIRKALTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGV8</accession>
    <name>A0AAD8UGV8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1-aminocyclopropane-1-carboxylate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_586181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000104">
        <property type="protein sequence ID" value="KAK1718099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361099.1">
        <property type="nucleotide sequence ID" value="XM_060505921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGV8"/>
    <dbReference type="GeneID" id="85389820"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000040">
        <property type="entry name" value="Chromosome 21, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-haem dioxygenase N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase" evidence="2">
        <location>
            <begin position="198"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="373" mass="41946" checksum="351E5D9752526B01" modified="2024-05-29" version="1">MTTSISETAPVHVPYVQATETTEQLDWADLVALDLSKFNKPGGKQELAIEFTRAIEQIGFFYVINHGLSREAIDQQYALASSVLSLSDEDKAPYRAALEAGDFNGWKPPGTRELVPGVRDNFEIYNIPKFIPEHASRSHPEVVKENLATIEWFSRYVNDEIVRKLLVIFALALGLEDEEWFVKKHLYEQSSGDHLRYMKYYARSEEENRKLGGVWLKGHSDMGSLTLLFRQPVAALQVLTNDGTWKWVRPQTDALTVNIADALQFLTNGYLKSSIHRVVAPPKDQAHIDRLGVIYMVRIEDDTDLIPIKESPVLQKLGLSEGAVLGSDGKPVKAGEWVRERIIKNIGTTSQSDGDNSVNDLEVLKGVKTTYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH60</accession>
    <name>A0AAD8UH60_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activator protein for ras-like GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_382094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363886.1">
        <property type="nucleotide sequence ID" value="XM_060502712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85386611"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05392">
        <property type="entry name" value="RasGAP_Neurofibromin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054071">
        <property type="entry name" value="PH_NF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF142">
        <property type="entry name" value="NEUROFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21877">
        <property type="entry name" value="PH_NF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="1207"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="2572" mass="285823" checksum="1E47AA7A9E0F83A6" modified="2024-05-29" version="1">MNGDAGLVGCLVDRLATRLPHRTGTHGQELQQDDVVLITRSTLVKISTSAVAFVLDSLVALLEDIIRNYKGLPPPAHPPHVLLSEVYVLALAADCCTAHWDQVKAQGIRQPSAEADTRRVTSANLANVPEPLDEALVNRVFDLVKWLVEPIPEGYVLPSSTILDDTSRHADSIARSSGGLASPLPGDTDATEDDETLSTTQLAVLEPCIRIIVEYVTASTWSCSFDYFRNVVYTVRTAAVVQAAPGQSAATPDDDKASLAVLKILSFFWVDAQKLGLIIQEICSSFLHFRKSFQNTVAVVAPLLVTRWLDRYPHEFVQQHTLHRRLDGGADTLFDMTQTVVDNGRKKGVLYPLQTTLLFLLPDVFEVASNLREAKSSSMAKKVGFLDNLRKALRNKNEQAAYSLVSLLRASRHFVAEDDAALVSYAMDVQDEVREAVFRRGNESSLFDQDLMTAAFVSLAELSLESCVDSLRESYLGLSSPQAFKTAVVQGCRYFARQNDSHIYEQLFAVAGPFMRTQLKAVADLPAEATAVALALPRRDSNLHSFTNMACDVLKFLDASPRSLFDGDSQSDTVTGAADEDVFLSFLSCVVSANPTIRRLATGVAKRLFSDSSIIDTLRARGRLSSVALRREFWRRSSLVLLNMCNDVTSDGNGSEVKAIHEYLEARKFLLASLRELSDMPEGVPEIEAASSRLETTLLVSLCSADVETCQTVTSCIGLFFEENNLVDITSDTAKVFATLLRNGEVYGEIASRAFRFTGLVAFQKRVRGLLRRLQYPTSGILSAWEYGFERWLLLSREVSMAPVDAVDERTLTEWRNYSGFLASLGGICTANQTIILEEPALNGLRWIDKLSSENHEEPLLSRYLKLSIQLLGCASVRIREATREVLSSEVSSTLYQALFKSLESELEVLFTGALAPSDKAQDVEIIFAEQAISLLKALVERLESPSDLGAASAIHLGALALNFAKFLDGIADSTNTLRVKIKVCQLCEAVTKRKEHLNLRDDVRIRNQLLEFIFGWIARPRSPRLDPSTSSSGRLDEVVRVQKDLDKACLKSLAELTFRLPLQPGEGQTDAGTSELKSQMFHTYFNRFLSLLNHESLEGGRNDLLAGISSRDEGGSSSEFAITILSNLLSANIDVGLKHSLNIGYHDNVEIRTAFVKVLYNILIQGTEFSNLTDAAVSEKYDELLELLTKDMTLVAAMSAVCPSSEVDELTVSLLTIFEHRGLSFELLEVLIKQEIEETDNESEILRRTCVATKMLSVYAKWKGQPYLKATLQKVVERLMLTSKDLDLELDPARVSSTDELQKNALQLRIVAKVFIDDICASSSTMPASFRRICNIISAAVLPRFQEAKYTAVGAFVFLRFFCPAIVAPEVEGLVTTTPSKEMRRGLLLIAKVIQNLANNVLFGAKEPYMFPLNDFLTQNIYKVTTFLREISVPPENLETPPTIESFDFGSCVALHRFLYDHWDHMRQRLVTQERKDFVRSPAEVSRGRSPVLEPLRNLITNLGPPPLAVTWNRPQISTNTPPSYSRFQNFMLRNAFRSTESFITARAVYDGGESKDSLSIICIILRHIDAESIDYDTLLYCYLKIASRLWHKPFGLLIDATCYNGQNEPQDELFKKLEQLTPVELSRNLVRVYVYNMNSAFRKCFRRLLRVSAKSDNSVFNPKNVDYHLIGSLQDLQAHFHLSQLHLPKETISVVTDTRYVFQPITRLSKTKGKIEVVIKVGSQFVQVTTTKKQEVFPGYRLSTTVNDIFRLGEVEEAPTSIQTEDDSAFGLRADNGKIVMYFTSPKKADVLQTIRGAKAKYGKDTRAHKAYERLIRPQDVPGTLLNLALTNLSSSDHVLRLSSYNLLGALCKAFKFGAASNLMCTKDVSVPMDPSHFIIKISRQLAASEPQLTFDFLTEFFVGWETFTDEQKPLSLAYMAPWLPGLRTGVLANESDAEKGKEKIAALFRKLIDVAMSDHGLTYTLEQAVWPAIYQDETILDIFLEELMRAALSFGFSEEPMEALSSIVSGMGSITLRGKVISRLRKALNRSSLRPTKYLPDNTVWAEICVLLHFCLSLSFDNGVQSQLYLPEIFHIVTILANTGAPEVRLLVHRLLVNTVHAACTSFNLDETRFNKLRGSLDFLSEPRSEIFSTPPPFLRDGASMSTTQDAGPSLAATENLAAVLFEVCSVAAPSIDISNAWRSRWMSLVASTAFQNNPAIQPRAFAVMGCLAREEVDDDLLYQVLVALRNSVGRLGDDTNSDMLISIVTSLSKMMAKLPSASRYGLQLFWLAISLLRLVPPALFNCTAQFLEAVMTNISTVGDLRGDKMGPLLLQGRVQLEEAALPLDDAYGIHFTPENFHFAVCACLARGLADTTTKTNAMRVLSAFLDMAGNPIGDTGKPSDDLSRSPYMALILARTVESDELRDSLWLAGIDPSLLRDITGQQRYDDLGGMKDKDLLLNTAIELIDFQYLEDALQNRTLQWLTELAAARPSVIMHLCGPIVSILDDVLLHCQNSSTLESAQDLLHALTSNPKFSTALESTAVLNEILEDMGFSGLWRSCSFNFSQDQDRKCFLLTEKLIEVSHNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH89</accession>
    <name>A0AAD8UH89_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arginase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_722049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361578.1">
        <property type="nucleotide sequence ID" value="XM_060512428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH89"/>
    <dbReference type="GeneID" id="85396326"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09999">
        <property type="entry name" value="Arginase-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1719494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="32160" checksum="5EE31F894DBE9095" modified="2024-05-29" version="1">MPYTSITIIVSPYHVGIPNHRVGTGPHRILYHGLADKLGNLVPIRFVNIGPVDDFEGEIGRTFELLRRISSAVSQAVAAHSFPLVLSGNCYASTAVAAGLNASVPDLNVLWIDAHDDLDTPSTNENGYLDAMALSMAAGMSWHKLMGSVPGHKPLSLDRVAYCGLRDVSELQRKTVAETGVDVIWGDAETKVDFAKELGMLLDRRRFEKTHVHLDLDVLDESLGRVNEFPSPGGLHEKDLMGCLETIPRKTSPTSLVVCSFNAELEGGDTVARLAVKGIVQFVERLIETEVLRAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHA1</accession>
    <name>A0AAD8UHA1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_654635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361634.1">
        <property type="nucleotide sequence ID" value="XM_060510733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHA1"/>
    <dbReference type="GeneID" id="85394632"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF7">
        <property type="entry name" value="ZINC BINDING OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="4">
        <location>
            <begin position="68"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="412" mass="42964" checksum="3DC12107E68C2D63" modified="2024-05-29" version="1">MSEQKTAPPPAIDVQEPAPAYERESPVTSTVQGSGPAPAREMPANLVQLDGPRRSLLKKALPCKCADGQLTIKQVTEDYTPQKLQALVSIKYSGINPCDLNFFHVGLNSFVTGFEFAGIVEAVGSESALQVGDAVLGISPVGFPQKSPACTHQDKAIVESNLTFKLPHGLALKDAGGLALTTQTAADAIFNVLGFAFPAAGVTGTGGTDKPILIWGGASSVGIAAIQLAKAAGFNPIFTTASVKNHAALQLLGATHCFDYKSPDVTGDIRAAAKSLGVSLTFGFDTVGSGLHGPNADSETSTPTLLRRSLSKGAEEISVKLVCTQPVAHDPAFGFCTCYRPVGSIGAMGHPQDPEFPTRVRKVMEYVLGSAERAPKHPNITVVKGGEAGLQEIQRVAYGGASLEKVVIEHPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHE4</accession>
    <name>A0AAD8UHE4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_654680</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361566.1">
        <property type="nucleotide sequence ID" value="XM_060510736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHE4"/>
    <dbReference type="GeneID" id="85394635"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1719482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="61013" checksum="8502F36C7D21A541" modified="2024-05-29" version="1">MATANDSFSNQSSWGPLETLQAFPSPLEKPVPYFITAFLLFVFYFSIQQAEQTPHTDLPIVNPKHKWDFTGLKVKYDFITKVRNIVLERAKTNPDEPYQVLTDMGDMTILPAVPFANEIRNHEDLSFDRVLDKNFHAQMPGFEPLKENNAQKAVLKYVIRTRLTQFLSKLTSPVSDEATLSLTNVLGEDKEWSTVVIKENMLRVVARVSTRVFGGEELCRNQDWIKITSEYARTSFLASEFLRMFPKSLRNLAHQVLPICRQLQAQVKEAREIINPIVEERRKEKKAALDRGEEEPEWNDCLDWCEEASDDAKSDPAMMQLGLSFAALHTTSDLITQVMLDLAKYPDYFEPLRKEISDVIRTDGWARMGLYKMRLLDSFCKETQRLHPIGIVAMHREATKPVTLSNGLELPEGSRIAVSCQRMTDGSVYLDPSRFDGYRYLRMRESLGAGNDGAAHFVSTSPEHLGFGHGQHACPGRFFAANEVKIILCHLLLKYDWRLAAEQQPNTINFGFTMEVDPKAKLEIRRRTGDLGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIJ8</accession>
    <name>A0AAD8UIJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gti1/Pac2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_430951</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIT1/WOR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362385.1">
        <property type="nucleotide sequence ID" value="XM_060503049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIJ8"/>
    <dbReference type="GeneID" id="85386948"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="453" mass="49613" checksum="03C7F365706F8BC1" modified="2024-05-29" version="1">MANSNVPLNPTFIGHVASTLDALVLFEACLSSALHHVPRRPHDRERQDLIKSGNVFIYEEHSSGIKRWTDGVAWSPSRILGNFLIYRELDRPFPPGEKKRAMKRNKKPTGVTKPEVARQGSVNGAASTMGMGDGSQGGNKDAERALIGSLVDSYPFKENGLVKKTISVTYQGVPHHLVSYYNVEDVTEGKLMTPSKDHQLSTIIPRGELIMSQNFRAPIDEVEMDDSRGGHGLFAQHYPVNGHHQSLSRAMSVPSLHMSGMPATQFGHPPYMSYMNPVPGSVSNVGYAQPQHPNYAYDSLSRAGRYPSSAGLAPDMSRNMALESQHHPRRHSTAYEPVTGPEMGLASSLPAVSSDPSRSMGGGNYMTSMLYSQQRPHDMSPHEPFPSPSPRHVHNESGMGGDRSAQGFPIEGLNRDTWNTFDQIGEDDQGQYMPQGSAGWPSSNNNNNSLGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIP5</accession>
    <name>A0AAD8UIP5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetylesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_705108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000087">
        <property type="protein sequence ID" value="KAK1721233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362029.1">
        <property type="nucleotide sequence ID" value="XM_060511503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIP5"/>
    <dbReference type="GeneID" id="85395401"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF85">
        <property type="entry name" value="A, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10760)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042067756" description="Acetylesterase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1721233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40181" checksum="74CB1BC6C58C9B45" modified="2024-05-29" version="1">MIVSRAYLLGWAAAVAVASPIAVETPFSWKNTEYVLTFGDSYTFVQGTEGRWAYSFIGSQLNISFTPEQLLGDRIVPGQNTSSAGGPNWVQELTGCKEGHPRDCEKQLWGFAYAGADISTTFVPLHWNHTISYEKQVEQWDTYGKSVIDADPTKSLVASYIGINDINDMANFQLPVNGLNSWEELYTAVIAEQFAALETVYEAGHRNFLFLNLPPLDKNPASQLNPARRPSTDMIKTFNGVVNQTAKAFSEKHPDATALVFDTYNWLTQVFDNAASYGFTNTSSFCPSYKAWDIDTNYAAYGCQPIYEYFWYNSGHITYHVHELLAQKVEEFLLQKSASGCGGKNQTLSAWGTTWIGGEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJR7</accession>
    <name>A0AAD8UJR7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_618696</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365682.1">
        <property type="nucleotide sequence ID" value="XM_060508084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJR7"/>
    <dbReference type="GeneID" id="85391983"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09865">
        <property type="entry name" value="PIN_ScUtp23p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000006">
        <property type="entry name" value="rRNA-processing protein UTP23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="9">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="171"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="34302" checksum="78F7BCAFEC9B3245" modified="2024-05-29" version="1">MRGKRSKQYRKLMNQYQLTWGFREPYQCLVDAEMVVDCHNFRYDLLAGLERTLHGKVKPMITQCEIRKLYLRKNEPDMNKIIDFAKTLERRRCGHLPEDYPEPLSTMECMKAVVDPKSNLVNKHRYCVASQSGDVRRMLREIPGVPQIYIKRSVMILEPMATESVAIRTKEEKSKFRDGLVRPERKRKREEDEEDDDDESGKEGKAGAGAQEQKKKDKKRGRKGPNPLAVKKAKRATNGGDAAHKEAKEARAAADGGEGEGEGPAKKKRRRRNKGQAAGDAADSSSTPAANQGEASTEQAAAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULD5</accession>
    <name>A0AAD8ULD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364125.1">
        <property type="nucleotide sequence ID" value="XM_060514269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULD5"/>
    <dbReference type="GeneID" id="85398167"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045992">
        <property type="entry name" value="DUF5948"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19373">
        <property type="entry name" value="DUF5948"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042005151" evidence="1">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="96" mass="10131" checksum="9198CB156E117B9F" modified="2024-05-29" version="1">MLSQYIFVIVAACAAGSFASIVTCKGSFYAGVCQDIFAPGAHHDALTQSCCQPPHDTTYHDGPETFCCTNADSLAIAYLSSCCSNGGKRQINFNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULD8</accession>
    <name>A0AAD8ULD8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_579865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000059">
        <property type="protein sequence ID" value="KAK1723889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363944.1">
        <property type="nucleotide sequence ID" value="XM_060505287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULD8"/>
    <dbReference type="GeneID" id="85389186"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF2">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042262165" evidence="5">
        <location>
            <begin position="20"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="5"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="436" mass="48226" checksum="6AF55805D7691B19" modified="2024-05-29" version="1">MAPLNILIIGCSIAGPTLATFLLMSPVPASEKPRITILERASVFRPQGQNIDIRGAGVTIIRKLGLEPAIRAATTGEEGVQLVDKENRVWAAFGADKSGKTQTPTSDIEILRGRLAQLLLEQSQKVNGEVQADGGAGIEYIFGDSLDDLEQDGDKVHVHFTKSGERRTFDLVVGADGVQSRTRILTWGEAGEEDRRRRLGMYGGFFSMPRGPTDSAWRRWFHAPGRRGIMIRPSGVEDRTTVFMAVVNEKDERLKAVAERKGGSTDAQKAILQEYFWGLGWETDRVIKEMIATDDFYYDTICQIKMDKWSKGRVVLLGDAGYCASPLSGMGTTLAMSGAYNLAGAILRHPNNLETAFGDYEEKMRPTVARAQKLAPGMPHSLHPETVWGVWLLNTVMFVLYWSGLFSFVARFAGPPANNVPIEEYGFKSLPIYQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULI3</accession>
    <name>A0AAD8ULI3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.12</ecNumber>
            <ecNumber evidence="10">1.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Xylitol dehydrogenase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_574524</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate degradation; L-arabinose degradation via L-arabinitol; D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="13"/>
    <dbReference type="EC" id="1.1.1.9" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366537.1">
        <property type="nucleotide sequence ID" value="XM_060504718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULI3"/>
    <dbReference type="GeneID" id="85388617"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046526">
        <property type="term" value="F:D-xylulose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019568">
        <property type="term" value="P:arabinose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0054">Arabinose catabolism</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="17">
        <location>
            <begin position="15"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1726482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="40447" checksum="2439C38FE12C532B" modified="2024-05-29" version="1">MAGTEGKSNLSFILNKPHDVEFAERPIPKLSDPHEVLVAVNYTGICGSDVHYWEHGAIGHFVVKDPMVLGHESAGTVIQVGENVKNLVVGDRIALEPGYPCRRCGDCLAGHYNLCPDMRFAATPPYDGTLAGFWTAPSDFCYKLPDNVSLQEGALIEPLAVAVHITKQAQITPGASVVVMGAGPVGLLCAAVARSFGATKVVSVDIVQSKLDFAKDLASTHTYLSQRISAEENAKALIKQCDLGAGADCVIDASGAEPSIQTSLHVVRMGGTYVQGGMGKSDINFPIMALCLKEVTARGSFRYGPGDYKLAIDLVANGSVNVKKLISGIVEFKQAEEAFKKVKEGQVIKILIAGPNEKVDGTFSTEVDPKKAAENGNQGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULN6</accession>
    <name>A0AAD8ULN6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_580039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363888.1">
        <property type="nucleotide sequence ID" value="XM_060505304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULN6"/>
    <dbReference type="GeneID" id="85389203"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37013">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_1G05950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7703" evidence="2">
        <location>
            <begin position="24"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="283" mass="31811" checksum="0F64B29DFF31D946" modified="2024-05-29" version="1">MSALIPQHVRDGCSTPAFEFILATVFHSIAMYNVVELDLWIWSTFVRRSGLYFWSFVIATNGIILYSVGFVLLAYTLRSPDYYMIFLLVLGTILMVSGQSMVLYSRLHLVRQEPLLLRSVLLMIIIFGAVTHIPTMVFQFGTTAKPSNLITWFKVLFVWRKVEMMMFCIEESIISGLYIHAAISFFRLKSSAHGNPRKDLATPLLVVNGFVIFLDLTLLASPFASLPTAQPAYRALVYSVKLKVEIKLLNSLVKITQHPTVLTLPTIPQSSTSEIPLANGQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULY2</accession>
    <name>A0AAD8ULY2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_620258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365312.1">
        <property type="nucleotide sequence ID" value="XM_060508183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULY2"/>
    <dbReference type="GeneID" id="85392082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="84" mass="9418" checksum="1C7CFEE257779CE8" modified="2024-05-29" version="1">MTPLSPLSSTHFLPYLVVLVYCTVLHASIPNLGGTMQRYKVTKGSRQDVSREAFPNSPRFYPYSSSIPNPHRDLRPSAEPEIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UME6</accession>
    <name>A0AAD8UME6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_719894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364544.1">
        <property type="nucleotide sequence ID" value="XM_060512221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UME6"/>
    <dbReference type="GeneID" id="85396119"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027915">
        <property type="entry name" value="DUF4452"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39615">
        <property type="entry name" value="YALI0E17897P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39615:SF1">
        <property type="entry name" value="YALI0E17897P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14618">
        <property type="entry name" value="DUF4452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="188" mass="20565" checksum="E05517A52A7F86E3" modified="2024-05-29" version="1">MSSYYQFNHHQAHPTPAVPGASHNHHGGRNRRAPRLSVSQNQHKQFRGVRSMKELTESATLNAFRTKFEAGRSFDLEDDMEFCPGLLTDSDMNSIHSSSERSSLASNSPESSPTQQPQTVAPGFSLNSSSPAFIPPAYQQSSLKLHQPAATRARNAIPIVNPATGITMSSPPPSVSPARMQQGMGRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMK0</accession>
    <name>A0AAD8UMK0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_719101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000040">
        <property type="protein sequence ID" value="KAK1725572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365627.1">
        <property type="nucleotide sequence ID" value="XM_060512143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UMK0"/>
    <dbReference type="GeneID" id="85396041"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097237">
        <property type="term" value="P:cellular response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="4">
        <location>
            <begin position="42"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="32673" checksum="1C939838BF85924F" modified="2024-05-29" version="1">MMTVLFDSNLYRNARASNMHNVLGFDHVPPPVFRAKAREDLRARYAETVTFADGVEVVKTTKVKDGLFRAEDKHGKAWFGRRLVLATGVTDISPDITGYADCWGYGIFHCLFCHGFEERGAERVGVLAFGLTGSVKMATHIAYMARPLGKKVTIYTHGNEALASEISAMTNNPFVIDTRKITSMRMAGGGEHSTSVTLTLGGKDGEEGEEITEGFLAHAPFTRPNGPFVEQLGLETAENGDIKTAAPFGETSVSGVYAVGDCGNMVKAVATAAASGALAAGGMVVPMQMEPRVKMDVEAMEKVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNE0</accession>
    <name>A0AAD8UNE0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365024.1">
        <property type="nucleotide sequence ID" value="XM_060508251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNE0"/>
    <dbReference type="GeneID" id="85392150"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="62" mass="6695" checksum="E16A0975D4B6F98B" modified="2024-05-29" version="1">MRAPLKILNEKLAASLNLSPPPTPCKVVQQATLPSSRPPPINVRRASYRPQLGLTPSPANCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNN1</accession>
    <name>A0AAD8UNN1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_621972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364686.1">
        <property type="nucleotide sequence ID" value="XM_060508303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNN1"/>
    <dbReference type="GeneID" id="85392202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="239" mass="25917" checksum="210497F0F79A2BDE" modified="2024-05-29" version="1">MGSTMHIQAAPLTILFVTRRGHDVAQSSKHISFRQPCSTSGSLSVARCAYTPFLPSALTIVAATVGHLICEERNQTVWHMGTMFAATSVSVASTAHPLRRSSADTSASLAGSCAFLTISCRLTTTRYKTPALVHVTPWQATLARFTIDFPLDTGTSIQPFLLGATAFSGSHLLTKSKSPLPSSSASLRFIGPCARSGHRYQNITSQFFDWVVSAVSTWVWMRDLNVLLRYPKSHDPASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP10</accession>
    <name>A0AAD8UP10_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_312252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365369.1">
        <property type="nucleotide sequence ID" value="XM_060502310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP10"/>
    <dbReference type="GeneID" id="85386209"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF85">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="4">
        <location>
            <begin position="227"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="533"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1725314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="637" mass="72006" checksum="7870851F014C023A" modified="2024-05-29" version="1">MAELKITRGHSCGPCQHRKIRCNAQARLLSQNGSATAKGQVVVSGDQRRYVEDNKLWSSLGNEMGKKDPSPTPSSTPTPSRIELPTTNINLIFGHKLDSPVMLHPSAIQSFRLWQVFTTNVHPLTKILHAPTVQQELIQGLSEPDSIHGPTEALIFSIYLVAVVSLTDEECRSQLGEPREKHLARYCYATEAALSRVDFLRSTNLKVLQAFTFYLLSLRHLCHHDILWLLTGLATRMGQRMGLHRESSLRDLPPFEAELRRRLWWQIVILDGRTAQLTGASMNPGIQLYGDTKQPLGVNDDYLVPSMSALPLPSPVTTEMVFCSVRIEIGVWMIEQKCLLDFATSHERRAKFLKSIDELESHIEEKYLRSINTDIPLNLLTTYLARSAVCQLRLSVYHPNHRPKRTSELDEEQMDMLLENSLEVIRYDILSHSTGSLQRFLWHIANFFPFETFVLLISALSGRAGGQIVDVAWHVINQVYEHHPCFITDSNDSLYWALGNLTLRAWQQRIAASRNVGMELPSEPPCIGQLARQRTNMSRNAQPKQQAPTLSTASDGPATPQEMPQVRDWLQDTGHASSMVQQPASYGQDIVMPGIEEEMSGITKGVDMDWNFWQELLDGNARESQECFPFSSFMNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UP26</accession>
    <name>A0AAD8UP26_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SWIB/MDM2 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_579991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363875.1">
        <property type="nucleotide sequence ID" value="XM_060505301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UP26"/>
    <dbReference type="GeneID" id="85389200"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10568">
        <property type="entry name" value="SWIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="240"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="470" mass="52599" checksum="30DC817C1452D413" modified="2024-05-29" version="1">MPPSHHAQAAMNQAAMAQHHPPGQALTSELAKRRSRKPTDKTLPDGVEECITDTEVAQRYKDLRDFERRLDAAMTRKRLDIVETVGRNAKHYKTLRIWISNTVEDQAWQGSGLSVDSFDFTPSAEPSYRVKIEGRLLEDGSDDASGESDQKTESAQGEGATGSRRQSSAPVSQKHRLSHFFKALNVDFDRTRSRAASDQTVDWKKPALQGAAASADFDEFTFKRSGDENMNITINLHRQEDPERYLLSPELADVVDMTEASRQEVVLAIWEYIKMMGLQEDEEKRNFRCDELLKKIVNGSDTGIIPNLNDYIQPHLQPLPPVSLPYTVRVDEDFHRDAQPTIYDVRVAVADPLRAKLVPFVTTPAYASALKEVVAMDEQLATLISAVASSKAKHSFFTSMSQDPTNFVRNWMSSQKRDLEIIMGEATRGGGEDATGDDWRRGGRDSVWTTSNARESVSVMLAKQAPQASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPA4</accession>
    <name>A0AAD8UPA4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_719155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365489.1">
        <property type="nucleotide sequence ID" value="XM_060512148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPA4"/>
    <dbReference type="GeneID" id="85396046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540">
        <property type="entry name" value="TRANSCRIPTION FACTOR (ACR-2), PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37540:SF9">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="67223" checksum="3AC5B20F77EF61E7" modified="2024-05-29" version="1">MIVIEYQSKCNWLRALDGEKLNANVVMRNSFSIICIIRQPETQCVNCSRRFPPVECTIVQLGPCLPKPVYETQVLTFDLSSLSPKSEKQTEVTSHGPCVTSLPGIASLKLPGRLPVRNRCREQIRSRYLEGHDHARLGGDCCKDNREEERAVSKGQARANLFLDGDGDPQAFFHNGIASIGGILTEVTTLHGMPLPEGPRTTELLHFYVHFVAPNMVSIDGRSQPPVFLKEVLPWMLQSPLFPNIGILMSSMTQSLERGTEVAKSPESLALKSWVLSMIADYMRRPFDAIAVEMVRCIVNLVVMEWFWGADESMFAHMRGIKRMIKLRKGMRGLRDIVGESIIILTDYEIACAFETDLYWLENDPARDEEIPVPTTWPDCYDSPLLASAPRFESIAEKLGICGATAKILDDVRFLTDSVTSASAMASAASKSKIRSTASWLYDKLREQGTATAARRPTQVASSSSEKERILETVRIATVIYSWSIKSLRQISRFDDAEMLQAAYASLTSVSMTTWKGIPGIFLWVMLVAAPNAAADAKGRFVRRKMAVTGLSIGFEDFALGISYLKAFWGVQRWIAREGGGEGEGAGVQRLEDKWSFGSWPGVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPP7</accession>
    <name>A0AAD8UPP7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPR1/FUN34/yaaH family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_740005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366662.1">
        <property type="nucleotide sequence ID" value="XM_060513052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPP7"/>
    <dbReference type="GeneID" id="85396950"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF7">
        <property type="entry name" value="MARVEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1726607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="25132" checksum="0A1CF6CA79D0387E" modified="2024-05-29" version="1">MSAETTCEVDIESIRPLATPKERLANSSPFGYGAFATTLMTLSLANMGIRNIENQAVFIANLCFLAGLGLLISAQWEMVRGNTFAYTTLIAFALYYGGYGFLLIPSVGIVDSYGGKTEQYYTAFGFYLAVWSLFNFFFFIAAFATNVANVIVYGGLELSYILNCSANFLFASGSASAGGTLAKIAGGFGFVAALAGFYVMAAEFCGEVLPFRIPLGDLSQLFPRKKSHRHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQ35</accession>
    <name>A0AAD8UQ35_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_611466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367951.1">
        <property type="nucleotide sequence ID" value="XM_060507658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQ35"/>
    <dbReference type="GeneID" id="85391557"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="55" mass="6901" checksum="B4807534737AD80F" modified="2024-05-29" version="1">MENIFLTSNYQTNELNPPNHDKWKWRTFRKRVRSYRVEGRIKFMRTNFHIFLIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQB8</accession>
    <name>A0AAD8UQB8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_302404</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365481.1">
        <property type="nucleotide sequence ID" value="XM_060502262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQB8"/>
    <dbReference type="GeneID" id="85386161"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000005">
        <property type="entry name" value="Nucleolar GTP-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="CP-type G" evidence="10">
        <location>
            <begin position="219"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="475"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="522"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="586"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="613" mass="67688" checksum="0DED828E6ECFB941" modified="2024-05-29" version="1">MGTGKKEASRKVRQGKTGDGMGNVKVKGENFYRSAKRVRQLNMYKDGKPQRNADGEITKAASFQSREIPNARIEPNRKWFGNTRVISQESLTAFRSAMAEKAADPYSVLLKSNKLPMSLIKDGADNVNGIKQHQAKMTIETSSFGDTFGPKSQRKRVKIGAGSIADLAGEVDKDLDKFNELQERNKLLSGQAGGADEDESHVTLSIEPIFNKGQSKRIWNELYRVLDSSDVVIHVLDARDPLGTRCRSVEKYLREEAPHKHLIFVLNKTDLVPTSVAARWVKHFSKDKPTLAMHSSLTNPFGKGSLIELLRQYAKLHSDRKQISVGLIGYPNVGKSSIVNTLRQKKVANVAPIPGETKVWQYITLTRKIYMIDCPGIVPPSQTDTPQDLLLRGVVRVENVHNPEQYIPAVLEKVKTHHMERTYGLKGWTNHVEFLEMLARKGGRLLKHGEADLDGVAKMVLNDFMRGKIPWFTPAPVEEEGTETAEGIEGRGGRLGEMPQKRKRDTTDVAESVADTSMGPSSDEEEEGDDEEFEGFGSDDDKAEGDKSLAEASEDAGEASDDMIPLDDVSDDDSASEDGGDGAASETSYNTSVRAVSDRSASNASKKRRKTKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQG8</accession>
    <name>A0AAD8UQG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal-specific transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_277220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366089.1">
        <property type="nucleotide sequence ID" value="XM_060502103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQG8"/>
    <dbReference type="GeneID" id="85386002"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF29">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="269"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="797"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="837" mass="91075" checksum="456E5F05E86C8B46" modified="2024-05-29" version="1">MHVITIFISITKNCSFHVRNSRIRCDGKFPCEQCVHASLTCKREHVPKKRGPKRGHGRVINELRARESSQGKQQPKVQKPFNAETALESPTDVDIGMSGSDLGEATSQHSSNASAASTPPSFWAAVTSNPAHSNVPEPRGIFSSDELRPRTRSYFHMIPQLVELYYEHIYPIMPLIYMPTVRETINRPMTPSEKNLIYALCALTSMHMSGKSIGAPGPTSWEVVGRFFLDETISTRQTYDFLEDLSLSAVISSFYLSTSFFEINQSRKSWYYLREALTNAQDLGLQDDSTYYGLSREETLCRQRVFWILFVTERSFAILRNKPITFKRTPSLPTTRHPYEGPDIHAGFLQLVSSYTPLDESFVTAWNEGSDPRVSATTFLALQNLLSLPPAFLRPHGRSSPPTQPHGQLMGSYGSTSASRDAGAPEPTDIQKADLLITQQWLRLIVWQSSMRQGLLSWTNPADSGGGVSSGSGVGGGNSMCFSFPLTVARDTASILSSLPSKAVEVHGMGIMEKIFEIGTWCVNVLGACESVGFSTAMDFTSGDMGVLGSGRKGASLDPIEFFVRTLSASDNSRKQFAEKLLTAAGENPGSMRTQLSPAMSGMSSAAAAMIAAGQAHHMMEQGWGQVGQQRGSVVGEVFDDNEENNGNNQQQRQQQQQQQRLDLGSNSMHHPSTIPSMGLGIDLGSDRLTGGMGGVDMDASSVDLMSPLGLTRSNTSDMAAMGMPVYDTAWSPSSGGTGPREYPEHNPGPYTNQREGAQGYPDMGNGMLMHDRMATGTGGPVGGPVGGENPGMDPRQQQQHQQQQHQGDNGGYDGRRPEDKNGGYPNGGRVGLWLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQN1</accession>
    <name>A0AAD8UQN1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450 monooxygenase ABA1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Abscisic acid biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Cytochrome P450 monooxygenase aba1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_227287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Hormone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367142.1">
        <property type="nucleotide sequence ID" value="XM_060501782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQN1"/>
    <dbReference type="GeneID" id="85385681"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000076">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF77">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="7 13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00079990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1727087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="505" mass="56475" checksum="C4EF346E3E9C3FD5" modified="2024-05-29" version="1">MALSNFTSYLNAGSTLLYVSFAFIIYYAVSSIIAYGRLRDFPGPLIGRFSYLWLIRNACSGRPAEHFTNLNRKHGSLVRIGPNDLVTDDPEILRRMNAARSTYGRSSWYDTTKLNPHEDSLFSLRDTGAHDKLKAKCAAGYAGKENLALEDGINSQVAGFVDLIRRKYVTIDDEVRPMDLGKTTQYFTLDVITRVAYGKEFGYLATDSDVHDYISTTEAAIPLLQLCSEVPWLANFMFSKPILGAVGPKHTDKSGLGKLMGVAKEVVGRRFGTDAKEEPDMLGAFIRHGVSQSECETEVLFQIIAGSDTTATAIRTTFLYLITSPRAYHTLKTEIITAVTQGRISSPITYEEGKAMPYLQAIIYEGLRMCAPFTGLCAKEVPVGGDTIDGHFIPSGTRIAQNVWGTLRRIDVFGKDADLFRPERWIEADAATKDKMQKTTELAFGYGRWGCAGKNVAFLELNKVFVELLRNFEFQILDPAKPWHSVNHNLFMQDNFWVRVTEHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQT0</accession>
    <name>A0AAD8UQT0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_576026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365721.1">
        <property type="nucleotide sequence ID" value="XM_060504879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQT0"/>
    <dbReference type="GeneID" id="85388778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF14">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1725666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="53181" checksum="0DBE9B33BA721655" modified="2024-05-29" version="1">MPPRRSHKKSRAGCKRCKSRKIKCDEVHPRCGNCLKHGVPCDFENPEMFDELLTALTPSNTQSSQSPIDRASSTAPSPSAHRAKTPSFSGSPPAMNCSPLYTTPSTAAVSATTTPNNRLLELRLMHQFTSMTSRTLVVNTPATQDIWTNTVPRLAFGGATYLADAMLAVAALHLRSFNPDDRALIRASHSYMASSLAAYCTTLQNGITEANAESLFLTAALIAFQSTATRIFIRDEADPSDPSSAYSLPLSWFHAFQGVKTVVATSWPWIRNSGVVIPIIDSQPVLQLDLDATSPTSFFGKLLDNLDEELQTEDTLMAMSTRQSYQHAIAVLNWAHKLPHRGAALAFPATVSKRFIELLEERRPRALTILACFFALLKGFESAVWWLDGVARREVMGIVSQFEATSPWWEHLEWPVRIALYKNTIIPPEVWGSDWVTEESKAEKGHNMTAESFVNHIEILTGVFQKAQQIPVTGITVPANAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR26</accession>
    <name>A0AAD8UR26_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Methylenetetrahydrofolate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="12">1.5.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BDZ83DRAFT_576093</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.15" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365704.1">
        <property type="nucleotide sequence ID" value="XM_060504891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR26"/>
    <dbReference type="GeneID" id="85388790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004487">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01079">
        <property type="entry name" value="NAD_bind_m-THF_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000255">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000012">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035812">
        <property type="entry name" value="m-THF_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="15">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="16">
        <location>
            <begin position="156"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00053076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00074830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAK1725649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="343" mass="37882" checksum="BDEC55AC84B156FD" modified="2024-05-29" version="1">MASNEAVPKTCKVILADTIAKRLLAEVHETLAKVQGNGASKPTLAAFLANDDPAALQYAEWSKKTCVENGFDFDLRRVDKEQLEEKITEANEDDKVDGIIVYYPIFPGNPLQDKYIQETVSLAKDVEGLCHQHIFNMYHNVRFLDPPQNLRKSILPCTPLAVVKILEHLQIYNPILAYGNRLFGKTITVINRSEVNGRPLAALLANDGATVYSVDITGVQLFTRGKGIKQIRHQVENKEGWGLEQVLPLSDVIIGGVPSEKYKISTDLIREGAVCINFSSHRNFDAPTVKEKAAIYVPSVGKVTIACLLRNLVRLIANRPTTKDNGNEDASTAQARSEAFTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR69</accession>
    <name>A0AAD8UR69_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_609408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368551.1">
        <property type="nucleotide sequence ID" value="XM_060507529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR69"/>
    <dbReference type="GeneID" id="85391428"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021276">
        <property type="entry name" value="DUF2855"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11017">
        <property type="entry name" value="DUF2855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="418" mass="46090" checksum="ABF0C54A027A763E" modified="2024-05-29" version="1">MVSEIHVISKHDLSKHETVAVDLPLPQLGASSIRVCTSLIGITSNNLSYAKLGDMLQWWNTWPVPLDAPAPYNDRAEWGIVPAWGFARVLESNIEAIPAKSLLYGYWPTSSHPVDLSLVPSEPKGHFHEVSEHRQGLGNIYNRYNLVDESAQSEEYRAWFANVSPIWNCGYVMNRFTFATEFKPVHPLGAGAGEWTEKDADLSSAVVVSLSASSRTGRSFSWNLARDRKSDGGPFALLQATSTPESLRAIPKAAFEIKTVNYSELAAQDTIDWIVKLQPKRVVVADFGGRPKETEEFREAIKSTLPDSTTFTNIQVGGEPKITAPEEALKSMAIFEKWGLVQLNTTGIVDAGIAVEGAGKYFDGAESTFQRFLEEESVADLELVWGSDVGGTNGIEKAWKNIIQGTLSPQNAWVYRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URR2</accession>
    <name>A0AAD8URR2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA repair protein rad9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_572242</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the rad9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367682.1">
        <property type="nucleotide sequence ID" value="XM_060504483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URR2"/>
    <dbReference type="GeneID" id="85388382"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026584">
        <property type="entry name" value="Rad9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009303">
        <property type="entry name" value="Cell_cycle_RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="288"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="457" mass="50852" checksum="D939E6A4B70CA987" modified="2024-05-29" version="1">MAVLNFTLSEDAVAAFRDVLACLNKFSDEVSLEAKKDKLVLTALNASKSAYSCFTFTTNRFCSRYQFEGSAQYRDKFYCTLYIRSLASIFRSRAGGDSQRDREKESTIDRCDVAIEDGPGVKSRFIVKLVFRNGVTSTHRLPFEVAVPVHAKFDRDETTHHWTIPSRTLRQLMEHFGPGVELLDINSDGEHVNFTCYTEKTTNGDEVLKKPLHTSIAIEVDEFEDIEVEDKLRIVISVKDFRAIIQHAGITGNHISARYSNPARPILFTYSGDGISCEFLLMTVGEKGNPAQKTKKGKAKGAQAAPQQQLEATSRRQSAAPSETPQPQEQPPAQSMPPPALSASASRSGIAARTSLFDLRPSQRPPPATMASQSLFVDDQDEQAWEPVRYEEDDDPDLDARLGWDHSNQPTASSMHLDRKVAEENAEFDPTPASSAGLEPTQRLDDVRRLGLFYQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US41</accession>
    <name>A0AAD8US41_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Laccase-like multicopper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_307240</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365465.1">
        <property type="nucleotide sequence ID" value="XM_060502287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US41"/>
    <dbReference type="GeneID" id="85386186"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13851">
        <property type="entry name" value="CuRO_1_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000071">
        <property type="entry name" value="Conidial pigment biosynthesis oxidase Abr1/brown 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041899598" evidence="8">
        <location>
            <begin position="17"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="149"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="358"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="574" mass="64012" checksum="25F5D7CB7FEE8ED3" modified="2024-05-29" version="1">MLRSLFALAWANTALAATVTYNWEATWVNAAPLNVSRAVIGINGQWPCPKIEATVGDTVVVHLTNKLGNQTTGIHFHGIDQVSTNWMDGPSMVTQCPLPPDMTMTYSFTADTGGTYWWHSHNMGQYPDGMRGPLIIHDPADPYAGQYDEEYILSVSDWYNSETIPLVQNMLLPSNTRFAPPIPDNMVVNDGLGAKFKFEKGKTYRIRMINFAAFASFMIHFDSHDMNVIMSDAAYIKQKASYMLRIAPAQRYDVLIKCIDRDNRNYGFLIAADINRDYSNKDFAQSWPFNYTGQLVMFPDRAFSTDVVKEWRPSDDAVFEPYGDVAILPAATKIFQYDWAFCFDKNGIPRACVNGTPYVDQKVPTLYTASTTGENNTNPLVYGAVHPFIVNYGDIVDIVVNNNNEANHPFHLHGHHFQVVRRPASGTGVWPGVARARLNQKPPRRDTVTVMGNSHAVLRFEAKNPGVYLFHCHIEWHVEMGLTATIIEAPERLRNLTIPDDHKAACRAQGIPTAGNAAGNTANVLDQTGMNLEPFPTYTGAAYNPPASPPTKRYNAPAHPPAQLRGRTIRRTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUZ8</accession>
    <name>A0AAD8UUZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_236055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366845.1">
        <property type="nucleotide sequence ID" value="XM_060501842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUZ8"/>
    <dbReference type="GeneID" id="85385741"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1726790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="391" mass="45697" checksum="8D1EBFFE69D497EF" modified="2024-05-29" version="1">MRPSQPQIAVQKKSVGVIKLLLDKGLACFLQDPWSNSVECNRYPFLLYQLKSLGQPSRYHDLEPTLRRLFLDNFLDDFLEDSKQVSVLLEFGISLSFLRLLLKRNNHMNTSFSFLTRLFHFRLVAVNCSWEACEIYSIFPEARCLDAHPGILAYSRNIKGYALFHSFVIGMAGNFTRKSCHPNPDQWAVSRDLWKRLLHDSIRLDYSSLHHIDRTSVWSKNKFMSSPLIAVINSVMAADYSILCTAEQVCKSLVATLSEWVTILSSSDVELLDYGREERHMYEQGLTAVSQRWAPWNYESRGTTRFSLLGITYGSSPSHWRLWWTYEYEDYAGEFWNMIQDEASKVPGAWVDDSWDPDDYREEVWDRLQAWEDEQPIPLIWSEHRRVRPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Y6</accession>
    <name>A0AAD8X8Y6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">1-aminocyclopropane-1-carboxylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_686157</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16933"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58360"/>
            <dbReference type="EC" id="3.5.99.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000267">
        <property type="protein sequence ID" value="KAK1704295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357402.1">
        <property type="nucleotide sequence ID" value="XM_060511259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Y6"/>
    <dbReference type="GeneID" id="85395158"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008660">
        <property type="term" value="F:1-aminocyclopropane-1-carboxylate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019148">
        <property type="term" value="F:D-cysteine desulfhydrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009310">
        <property type="term" value="P:amine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06449">
        <property type="entry name" value="ACCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000048">
        <property type="entry name" value="1-aminocyclopropane-1-carboxylate deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005965">
        <property type="entry name" value="ACP_carboxylate_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01274">
        <property type="entry name" value="ACC_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780:SF2">
        <property type="entry name" value="1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="8">
        <location>
            <begin position="19"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1704295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="345" mass="36733" checksum="FCFFB7B92761F5B4" modified="2024-05-29" version="1">MAAVLPEPFASIPRENFLFGPSPIEPLPRISAALGGKVNVYAKREDCNSGLAYGGNKTRKLEYLASDALAQGCDTLVSIGGVQSNHTRQVTAVAAKLGLKAALVQEKWVDWTDPVYDKVGNLQLSRLMGADVRLDPSTFGIEHKNTLANLKEELLAAGRKPYYIPAGASDHPLGGLGFARWAFEVQAQEKELGVFFDTVIVCAVTGSTMAGMVAGFKLAEKLGGKKRKVIGIDASATVKQTFDQVLRIAKNTGAKIGLEEGDITEADIILDDRFHGGVYGIPDQVTIDAIKFGASTEGFITDPVYEGKSLAGMMQLIKNEEIAAGSNVLYAHLGGQLALNAYSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9S7</accession>
    <name>A0AAD8X9S7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_589214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359799.1">
        <property type="nucleotide sequence ID" value="XM_060506212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9S7"/>
    <dbReference type="GeneID" id="85390111"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022025">
        <property type="entry name" value="Amidoligase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36847:SF1">
        <property type="entry name" value="AMIDOLIGASE ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12224">
        <property type="entry name" value="Amidoligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="758" mass="85574" checksum="9EAACDE98B3663E3" modified="2024-05-29" version="1">MTPHTSAIIISICSALKPSKNLTIALNEVPRLSVEVKPTEGDFTLPEVRRILNFLWFASPRLNELHAPYCGPGSLVAPGLEFARMFSTDIHAFLSDAEWRGEPTEAFFTRGLPTANKVKMLEPPSIRGLDIENEAIIRVNTTESFNDIMNGTEIHVRDWEGRPGIFPGAYDFSRLLDRDPTKRTIGFSQHAGTLDSAAIENWIKVCHGIVNICLNETEDRVEGVLGKLKLPRSAVGFSGSYTATQFLEDINLHEQAAYYEPLGRTPFVPELDTHRLRRPAINFEEEEDLSPYTFGIELEFLVPFTNTKYTGKGIKDQRWVYDHFTPYVIPNERGQAHDESAKHLETILCDAGHFSATFDTIFDLQDKFEGKVCIDGIQSVADAMGCHLHFFEDILAEFQCWYIERDPSLSDWASGEKGYAGHIGIEMSSPILRDSPKDFGKIVDVLRILRGGLRPMLDISCGLHVHVGSVRGFSLHSLKRIATLIMIVDPILYTLVHPSRQWSPMTEPLHLEATVAKAEDLPDYTAAFEFEDAYDKSESNPLQVVMSKVLLDLEANVPMNDLPRKLRGQLAKLWATDSLASFLGQLAPFRGCKGGTAFGALKWDFTKPSNGPRVKGTIEFRMLEGTLDPVLITHWTKLLLRIVEKGDAATTKEYFAMLSTLAEERENADEKLAALLGALGLERHLSFWSKVMQKNQAMDVDLEENDYGRKIMPEDWELPIYREAEGNRQEFERGWYERNVVRLPELDEDIWDRIIGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA11</accession>
    <name>A0AAD8XA11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_645635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="JAHMHS010000365">
        <property type="protein sequence ID" value="KAK1701588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357009.1">
        <property type="nucleotide sequence ID" value="XM_060509869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA11"/>
    <dbReference type="GeneID" id="85393768"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF49">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="64"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1701588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="447" mass="48975" checksum="7A7CA29CAC4622DA" modified="2024-05-29" version="1">MASAFHGGVIHSLGPNQVEILDSAGIVVGSDGLISQFYTQISVDELSAKLPIDQKVKVLAKGQFISPGFIDTHNHAPQWAMRGQGQGLHILDWLDQVTFPHEARFSDPAYARKIYESCVKGFLKQGITAASYYGSKHAEATQILADICHQLNQRAFIGKCNMDRNAPSYLHDESAESSLKETEECVKHIRKIDPTGQLIRPVLTPRFAICCTPDLLKGLGQMASQDPELAIQTHFNEAEQEIKATRELFPQFSSEVDLYQHYGLLNQRSILAHCTFMTDYEMDRIKELQCGVAHCPISNMTVGGGFMAASVRQFLTKGIKVGLGTDSGGGFSSSMLDSIRQAIIASNAREVMSGGKDKAISLDEVFYLSTLGGAQVCCLEDMIGNFAIGKAFDAILVTSSLDEASGVMTVREETDSLRTVFEKFLMTGDDRNIAQVYVQGRLVKDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAA7</accession>
    <name>A0AAD8XAA7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000286">
        <property type="protein sequence ID" value="KAK1703247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357264.1">
        <property type="nucleotide sequence ID" value="XM_060509799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAA7"/>
    <dbReference type="GeneID" id="85393698"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042210163" evidence="1">
        <location>
            <begin position="26"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1703247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="125" mass="12936" checksum="65B4D1E6D9A21348" modified="2024-05-29" version="1">MKTQHITLPTIQIAAAAFFAASAEAKVYCADTAGKVVAQASCDGNQPAKTFFLAEHEGDDLQLGDFIAEDKVDASHSVARGLETLETEAEQVSGGFGRRSPQRQCDPSLGHCVVSGVGKGGNNGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAD6</accession>
    <name>A0AAD8XAD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_120944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000162">
        <property type="protein sequence ID" value="KAK1711218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359021.1">
        <property type="nucleotide sequence ID" value="XM_060501147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAD6"/>
    <dbReference type="GeneID" id="85385046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="174" mass="18706" checksum="8B1808FC17006283" modified="2024-05-29" version="1">MGAALREKARGDLLLSVLLGASASSSSSPCLGVLYLSAPNSHQDGCRQDVATNSWLFLPVPLGGCAAKGDPSCRCCLSFMAPDRKENRPLVRDTQGRCAGTAVGVQVRMGNDECKCVPICIHVCQDSQARYLRKGIRMLVRYGQSRISSCLRVQRRRAAASHGQQNIIAVSDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAP3</accession>
    <name>A0AAD8XAP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_587937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360322.1">
        <property type="nucleotide sequence ID" value="XM_060506085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAP3"/>
    <dbReference type="GeneID" id="85389984"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="140" mass="16008" checksum="37547992428F18C6" modified="2024-05-29" version="1">MADAGNNQQQKAKSLQTTKTPEPRLDQQLANDHDNGNNTPSTPGIFPAFDWEDFEARYEKALADADDKERELLLEFDGLVKYFNVWASTSSAHDNERAVKRLHTRQRFVNLEEQNMAQKQEHMTEVLRAFQSALALLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAV6</accession>
    <name>A0AAD8XAV6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_724726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000225">
        <property type="protein sequence ID" value="KAK1706448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357848.1">
        <property type="nucleotide sequence ID" value="XM_060512691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAV6"/>
    <dbReference type="GeneID" id="85396589"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22477" checksum="EAAB092BDF6540CB" modified="2024-05-29" version="1">MFKLLPSSAELRGIDMDTIKFPPPSDLPPNISILQHNALKPFPEEMHGSFDMVHIRLIGSGMRKEDWRTVAANAFTLLRSGGYIHWEEAGDTSWKCVPPSHAFDEWSRIRLFCMPAQLALVLRDAGFADVDDKFGTFSSMRKIATEVAQPVMLSILESGGVDTLQTTKDMYRLESELKRDIQNGALIGISLTWFWVRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB50</accession>
    <name>A0AAD8XB50_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polyamine transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_586977</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000110">
        <property type="protein sequence ID" value="KAK1716857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360787.1">
        <property type="nucleotide sequence ID" value="XM_060505994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB50"/>
    <dbReference type="GeneID" id="85389893"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="80"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1716857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="518" mass="56669" checksum="DF7E7897BDBB186A" modified="2024-05-29" version="1">MADLKSPDSAPRDVDVEKGISPNASDLEGATIRPESRQEPEENAQDAAKEAHQDPNVVDWDGPDDPENPQNWPMKKKWFNIATISMLTFVTPLGSSMFAPGIPKIMVEFHETSATVATFVVSVYVLGFAFGPLIIAPMSEVFGRARLYIYGNILFTIFTVGTALSQNMAMMMAFRFLMGLAGAVPVTIGSGSIADIMPIEQRGRAMSAWALGPLLGPCIGPVAGGYLIKAAGWRWVYWLVTIVGGIFIPLSWFMMKETFAPLILERKVARLRKETGNTNLRSKLDDGQTTKQKFQHAIVRPVKLLFVTPIVTLMALYVAITYGILYLLITTFSFVYRDQYGFDEGTIGLTFLPAGIGMMIGVGTFGALTDFIVIRNKKKGLVHRPEARLTPVLTMPCGVVLPIGLFIYGWTTEKGVHFIVPMLGVVIFATGLMGVMMCIQNYLLDTYPRYAASVTAALAVLRSLAGALLPLGGLEMYNALGLGWGNSLLAFISVALIPIPLVFYIFGERIRGRFKPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE23</accession>
    <name>A0AAD8XE23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_753152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000060">
        <property type="protein sequence ID" value="KAK1723777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363832.1">
        <property type="nucleotide sequence ID" value="XM_060514313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE23"/>
    <dbReference type="GeneID" id="85398211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1723777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="77" mass="8170" checksum="8C92A1CB7C253E7C" modified="2024-05-29" version="1">MQPATNKAVLLIAFAINSSPRFGAVVVCSSMHVATDSYTITLRMEMPSDPHAYEAHTVPLQTHGISKSVTTPAGCPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEE7</accession>
    <name>A0AAD8XEE7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Aspartic peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_581095</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363326.1">
        <property type="nucleotide sequence ID" value="XM_060505424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEE7"/>
    <dbReference type="GeneID" id="85389323"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000026">
        <property type="entry name" value="Endothiapepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF23">
        <property type="entry name" value="ASPARTIC ENDOPEPTIDASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G15950)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041981249" evidence="12">
        <location>
            <begin position="22"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="109"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="437" mass="46288" checksum="252357A2390DDB22" modified="2024-05-29" version="1">MESTSLRSLVLYGLLSTFADASPVEKRANIQKRGHFLVPRVPNDNFAGHNGPRQLIKAYRKYSMPIPQGLQDAMDAMAAQNPSPEPTAAAGQPGTGLVTATPIRNDVEYVSPIKIGGQEVNVDFDSGSSDLWVFTSMLDATSQTGHQLYDPTKSTNAKMLSGQQFSIRYGDGSGAQGVVGTDVVDIGGAVVQEQAVEMATAVSQQFVQDTANNGLLGLAFSKLNTVKPTAQKTFFDNVMPSLAEPVFTADLRKKTVGAYEFGRIDSSKFTGQMAWIPVNTTSGFWQFSSEKFQVAGGQVQQGTAGAQAIADTGTTLILANPPMVQAYYQQVQGAKQDQQVGGITFPCNAQLPDLMMDIGGVYMARVKGADINFAQVDAQTCFGGLQATTSKLQIYGDIMFKSQFVAFNGGNMSLGMAEHVVNSQQAAAPATGAGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFD2</accession>
    <name>A0AAD8XFD2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="6">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NCS6</name>
        <name evidence="6" type="synonym">CTU1</name>
        <name evidence="11" type="ORF">BDZ83DRAFT_751857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFD2"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000132">
        <property type="entry name" value="Cytoplasmic tRNA 2-thiolation protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032442">
        <property type="entry name" value="CTU1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020554">
        <property type="entry name" value="UPF0021_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16503">
        <property type="entry name" value="zn-ribbon_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01263">
        <property type="entry name" value="UPF0021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="9">
        <location>
            <begin position="53"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Cytoplasmic tRNA 2-thiolation protein 1 C-terminal" evidence="10">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004976-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="44078" checksum="366DE89D7AB762E6" modified="2024-05-29" version="1">MAPVLCAKCKTERALVKRPKNHQKLCKACFISVFEEEVHHTIVSSSLFSRGEQVAIGASGGKDSTVLASVLKTLNDRYDYGLNLVLLSIDEGIKGYRDDSLETVKRNAVQYDMPLTIVGYDELYGWTMDQVVEVIGKKGNCTYCGVFRRQALDRGARILNIKHVVTGHNADDVAETILMNLLRGDLPRLGRSTSIVTGDDTSDVKRSKPLKYSYEKEIVLYAHHKKLDYFSTECIYSPEAFRGTARTLIKNLERVRPSAILDIVRSGEDMARLVAGGSGSSCACKGSAPRVAEDDFVAGCGSQQSKGLETEIAQLDASLSQTTLAKSQETDFTTAPSPSPKIGKKIQNSSETPRSRHGQAQATPNAPLQTLGKCERCGYMSSQAICQACLLVDGLNKNKAQISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFK1</accession>
    <name>A0AAD8XFK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arid/bright DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_274525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366024.1">
        <property type="nucleotide sequence ID" value="XM_060502083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFK1"/>
    <dbReference type="GeneID" id="85385982"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000021">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit rsc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="RFX-type winged-helix" evidence="7">
        <location>
            <begin position="654"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="216"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="954" mass="106910" checksum="1E8FF642E3D90A43" modified="2024-05-29" version="1">MAPKEAEVELHAISRTPEYEEFMAKLKAYHQERGTALEAEPKVGPVYLDLYKTFTHICANGGYDKVSDEKLAWRRMAEQLGIHSSNVASTAFSLKEKYYKNLAAYEIKFFHGKEPPPKDILEDVSAKGGGLLSRTRENFRGAKRDSGTAADSAAASGDDGTPTRERPTPDAAPTSSVRASRGLREAPPQRVIFQPDTGPARPTRHVSGQQPSHLNTPTPGGHSGSHHGTPQQVQHTPVPLPHQPRAPPRGPSGSYNPPNPDNSSASVESYLPRSLQPPNQQHVLPMRPVDTPSNNPAEFARRRHVARSLLEPPRRSGPYPGVGFEGPNIYIRCLMALRSAIFEEQQFALYHLVKISYERHDKFKFEGFPGLSEGLVEKVLEIGSIFYDVKWKISWVSQNAVDYFDTLDGNEGTEDILERIDSLEPKEVNELIVPEHLSDQMVLVNEAALTLRNMSQLRENAAHLAEFLPIKDLICIVLSLPKHEWLVELKHQMLDIAEALTPYLEIDSRDPLYKVLMKQLKGSDDRGIILTALRALGRISMNLEATNRLDKVPTAILTKISELMLLNDDELKDACLDFLYQYTAVVGNVDNLVKSLNCEHLIHHLVRLLSHNARRYQVEEVLKPAPKPATSNDPAAMPEDLLQDLLKLEEPERCNQWVKCFFEEVNDSFVTQIAAWQAYQNAFKAALQAIDQPLITPADFIRNSCAAYKSSKAEVWAGTGNPGQVQQKFIIRGIQCRLRPVGLDGQVFVRCLWDSASGRPNEKCGHFFGTKETMWKHVVTTHLKWVRNDKGGFDNKEEEVRCQWADCAKYKKPTKMKLALMGHHLQTHCCQSFNGIAINEKKAQAGLQPSDSLVVHFEETATAPDEQNPAAPPQAAGIPLSAVLILRNIARNVVKTRAQEDLLKQHELGGEAGGWNERLFRNVLPRLYEIMTENKVLRSHVFSLIEFAESERDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFQ7</accession>
    <name>A0AAD8XFQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_702893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363128.1">
        <property type="nucleotide sequence ID" value="XM_060511470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFQ7"/>
    <dbReference type="GeneID" id="85395368"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051698">
        <property type="term" value="F:saccharopine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF26">
        <property type="entry name" value="L-SACCHAROPINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="403" mass="44538" checksum="DF6ABD2A3861C688" modified="2024-05-29" version="1">MAKPSILIVGGGVFGTSTAYHLSQRGYENVTVLDRFDAPSKDSAATDLNKVVRADYPNPLYAKLGMESMQEWKDPKSIFAGMYRESGWVMAGHGLTRGWLNSAMETAKKAGREGVRFMTAGEMKTRWPALTGEFPDWTNLWSPAAGWVPSGQALLRMANAAKSQGVKYICGESGYAKKLVLDGNGKCEGVLAADGTLHVADIVVVSTGANTATLVDAKKEVVAQTSVICVMKLEPHEIENCRCLTNYRNRYVPGASILHSLGDYPDDGCPKEVEDEMRTFVREMIPELADRPFISSKMCWDGLAGDLNFRICPYPETQNLFVATIGSNHGFKFLPIIGKYVADMLEGKLGKEWQDLWAWKFGKVPDDFQDPHPWPLRDISDLSGWKGRNAVGDGKLPWTWSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFV9</accession>
    <name>A0AAD8XFV9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Eukaryotic translation initiation factor 2A</fullName>
            <shortName evidence="8">eIF-2A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_577912</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the WD repeat EIF2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364856.1">
        <property type="nucleotide sequence ID" value="XM_060505073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFV9"/>
    <dbReference type="GeneID" id="85388972"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000596">
        <property type="entry name" value="Eukaryotic translation initiation factor 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011387">
        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017222">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="10">
        <location>
            <begin position="217"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="477"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="506"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1724801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="693" mass="74850" checksum="3CDE7D5BE650937B" modified="2024-05-29" version="1">MASSQLQFAYRTQKGIGLFDAAPSYQPVSGFTNPEGNLRCCAYSPCGRYFAWASPEVVTVVDASTGQQVLALPILNVLELGFSPLGTFLVTWERPGKDENGDATKNLKVWRTVEDGVAGADKLPLGKYVQKSQGGWNLQYTADEKFCARQVTNEVQFYESHDLGTVWNKLRVEGVADFALAPGRSHSVAVFIPERKGQPAAVKVYNVPQFNAPISQKTFFKGDKVQLKWNQLGTSILVLAQTDVDKSNKSYYGETTLYLLSVNGSFDARVSLDKEGPIHDVTWSPNSKEFGVVYGYMPAKTTIFNHRAVAQHSFPLGPRNTIIFSPTGRFALVAGFGNLAGQIDVIDLEKDFRKLHTIESGNPSVCTWSPDSRYIMTATTSPRLRVDNGIKLWHVSGPLMYNEDKVELYHVVWRPLAVEKVAGGDPLNPVPTPHASAATYLGSVKTPSKPAGAYRPPGARGLATPLHFKREDEGGAAHISMNNGSAPIGPNGFGRPRRGVPGAEFAVPGAAPKVPGADPNDDENLSKAALKNKKKRNNRKKDGEINPEGQNGGGASLAPPPRDFGAGSGHEGRSPERRGGAGGNHRHRSHSRNPGAGQHRNRSNTHRGQNGAPQVPNAQPQQATPVTVTSPGADNSQNPNAKKIRSLQKKVRAIEDLEMRLAGGEKLEDTQMKKIGTKSSVLKELDGLGGEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFY3</accession>
    <name>A0AAD8XFY3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Gentiobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Gentiobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Probable beta-glucosidase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_650556</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000033">
        <property type="protein sequence ID" value="KAK1726389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366444.1">
        <property type="nucleotide sequence ID" value="XM_060510387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFY3"/>
    <dbReference type="GeneID" id="85394286"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 24" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042115987" description="Beta-glucosidase cel3A" evidence="22">
        <location>
            <begin position="21"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="23">
        <location>
            <begin position="698"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1726389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="783" mass="83950" checksum="53EFFB3E75CE479C" modified="2024-05-29" version="1">MFSKVWFFAAGATFLGPSLSQSLPAGHSLSWTEASVAAKDFVSQLTTVEKIGLATGGYSSPNLPCVGTIGSIERLGFEGVCYSDGPSGYSRSDGVSVFPAGISTAATWDKDLMYRRAVALGEEFRAKGAHVHLGPSSGPLGRHAVGGRNWEGFGPDPYLAGVAMNASVIGIQSVGVQACSKHFIGNEQETQRTSTISDNGTTIEAISSDIDGRTLHELYLWPFANAIKAGTASIMCSYNRVNGNYSCANSETISILKDELAFPGYVVSDWYATHETLSSANSGLDLEMPGNVSAAAGASYFGDSLLEAVNSGLVSADRLGDMATRVLTPYFLLGQDKKFPPTDPSSGAAFLRYQYGHQVQLPLTYPEVPARDVRGNHAELIRDIGSAGTVLLKNVNGTLPLTDELNVGVFGNDAPYPTIGSVFLDIGTRPEGFEMGTVDIGGGSGTVRHTDLVSPFEAIRKHVESIGGRVQALFDNDELVDGRFRTIYPVPDVCLLFLKSYATEGQDRQSAELQWSATKAVENIAAVCPNTVVVIHGPGVVVIPWADNENVTAILNAHYPGEQTGSSIVDVLWGMVEPSGRLPYSIPENESDYGPSIVNLTGPITDPDAWHSAFEEGQMIDYRHLDANDIESRYEFGFGLSYTEFDMEDALEIEVDANVSSVADEANGVEPGGLSDLWKVVASTSIQVTNSGDLAGSAVPQLYVSFPISTTPEGTPVKVLRGFEKVHLEVGETRSVAFQLMRRDLSFWDTEKKQWVIPSGTFRFMVGFSSKDIRAQAEAQVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG06</accession>
    <name>A0AAD8XG06_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Neutral protease 2</fullName>
            <ecNumber evidence="13">3.4.24.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Deuterolysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_784445</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Preferential cleavage of bonds with hydrophobic residues in P1'. Also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain.</text>
            <dbReference type="EC" id="3.4.24.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase M35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.39" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362185.1">
        <property type="nucleotide sequence ID" value="XM_060515608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG06"/>
    <dbReference type="GeneID" id="85399506"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11008">
        <property type="entry name" value="M35_deuterolysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001384">
        <property type="entry name" value="Peptidase_M35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF3">
        <property type="entry name" value="NEUTRAL PROTEASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02102">
        <property type="entry name" value="Peptidase_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00768">
        <property type="entry name" value="DEUTEROLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041776061" description="Neutral protease 2" evidence="13">
        <location>
            <begin position="19"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601384-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1721389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="374" mass="40155" checksum="CCC59B5501D35524" modified="2024-05-29" version="1">MLWRKVFAFAPLVAIASGHPNAHGIRYSKRDSTLEVTLAPVVSESGAEVSATIKNTGSLDLNLLKVGTILDDKLPVQRVSIVDESGNAVSFRGIDPSIQYDALKPIHFESLPAGDSVTVSIDASKVHQFTQSGTYSITAEGTIPIALAPSTDFSQPAVAFKSNTIQVDVDADAAAKSLVAAALKERTNLQPGCNATTLNASTKALANCQVLALAAAADAADPSSRRFVEYFGTNSSETRDIVVTRLRNVAQECSSTTSGVSRYFCYDYYGVCELDGPLNAYTAWDVNTMVMCPLFFGLPPLPVGCHRQCQATTTIHETTHCEAVYAPHTDDYAYAYNASVALPPERALQNADNYSLYANGMLPYVPFLACDMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG49</accession>
    <name>A0AAD8XG49_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_794446</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362290.1">
        <property type="nucleotide sequence ID" value="XM_060515815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG49"/>
    <dbReference type="GeneID" id="85399713"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106094" evidence="10">
        <location>
            <begin position="19"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="140"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="12">
        <location>
            <begin position="609"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1722235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="912" mass="99350" checksum="4F39E00B09313CAE" modified="2024-05-29" version="1">MRLYAVVAILSFAGTSLARFGQQQQTPSENPSSRTRRFIVELTKDSDIKQLQTDLCAFTGATVYKTFRSDVFTGVSVELTGNNEEDLGFLRDASNVWPSRRVQRAVVEDGQEFSRGFSGDNYNIHGITGVQRLHEKGILGKGVKVAVVDAGIDYTHPALGGGFGEGFKVMGGYDLVGDSDWPSGDGPKRPDKDPYEQDSLGGHGTHVSGIVAGQSDTWQGVAPEANILSYKVFSGTSGDTDEETLIEAFLMAHNDGADIITASIGGRGGFSSNAWAEIASRLVDQGVFVTISAGNTGEGGAFLGDNGQSGRSVLSVASTEPSYVPGMPFEVTFDYANSDVNKSRYGFFYGGLTHSFPLNSSLPITALSYDPLNTTIGCRFLPPGTVNLTSALVMVPRGGCNGFNKRYALQSAGAKYMLLFNDNETFPMPNSYDVYRTEGITEHAVGVDILAALAKGAKVTARFFNESDSNLVNLRNPAVVSSYFTSMGGLYDLQIKPDIAAPGSNIFSTIPHGKYGLKSGTSMATPYIAGVAALFISKHGGRKVHGAGFGKMLSARILSSGDSLPWNNGLNMTDYGTTRAPIFQLGNGLVNATKVLDYGTELSYTKFVLNDTANFRASHSVMITNNCTSPITYSFCVETAGTYEVLDDRDNIKMGPQYTGLVPLATPLVPNVTFPKEFTVGAGETREAKFTFEHPKGGNHSAMPLYSGKIRIHGSNGEQLSAPYMGVASDLRKTFRKMFVDDYPYINSGADDIPMIYKTNFSFDLSLEAQDFPKLYMNFRWGCSVLRWDIFERGWEEKSWGTYPPIPGEGGFVGHAATWDNERHATVFDPDNDNEFDLIRGPMGEFSREDYNYAPWRVWWLGRFSDGSKIKPGNYTMRVAALNPFGDPTKSDHWDIWRRDFMVIGNQTSPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG55</accession>
    <name>A0AAD8XG55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_752190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1725011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365066.1">
        <property type="nucleotide sequence ID" value="XM_060514160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG55"/>
    <dbReference type="GeneID" id="85398058"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12809">
        <property type="entry name" value="Esterase_713_like-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042055304" evidence="1">
        <location>
            <begin position="20"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="392" mass="42708" checksum="DF6408E71EDC89DB" modified="2024-05-29" version="1">MVCLSIASILFFGVVATQALVSGNCTGVNAISTKCASKEAAHTRDFFYVGGRYIETTSGNVTVDQLYVEKLVPVTTSRTRRRSNVTTPKPIVFFHGGGTTGVTWLNTPDNRPGWATFFLQQGHTVYLADTAAIGRSTENNLANFTMIAGAAAEGVERGFTHVEAYDAYPQAILHTQWPGTGQKGDPTFEQFKTTILPLSTSWVPQEYALRASGCELLSLLGEKAYLISHSIGARAPILLSNDCPEYIAGNINLEGTTVPFWSFESRSATNAWGLTNTPLDYNPAIASAAELETEVVGNDTAAHRSCYRQKEPARQLPKIASVPYLMVTTEASVHVTYDHCTVDYLKQVGGQPEWIKLGDIGIHGNGHFMHLEKNSLEIAEVVNKWIQEKEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGL6</accession>
    <name>A0AAD8XGL6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_653725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362680.1">
        <property type="nucleotide sequence ID" value="XM_060510638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGL6"/>
    <dbReference type="GeneID" id="85394537"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053008">
        <property type="entry name" value="Phomopsin_biosynth_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35896:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="18707" checksum="9902A11856A8FF90" modified="2024-05-29" version="1">MTPARPPEPVSLGKCSPDWKESKARGCVYDFMLSTWMHPRCFNEEMHEKYLGYMKWRNTTYWYERERINEVPFDVAASGEHGEIFTDGTIHHMHCSYVWDRITYASHFKPRVLDSLCRDPKHVEHCILYNGIPQSWEIDLPNITRVYNEPHEVDCLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH56</accession>
    <name>A0AAD8XH56_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PLC-like phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_699809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000049">
        <property type="protein sequence ID" value="KAK1724648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364703.1">
        <property type="nucleotide sequence ID" value="XM_060511419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH56"/>
    <dbReference type="GeneID" id="85395317"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF146">
        <property type="entry name" value="PLC-LIKE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26146">
        <property type="entry name" value="PI-PLC_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214073" evidence="1">
        <location>
            <begin position="17"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="286" mass="31866" checksum="7616031242388838" modified="2024-05-29" version="1">MRVACFLPAFVGVVAAAACNGNDALCAKKYSDVTFVGSHNSAFVGITPAHNQYVSVTDQLDLGVRFLQAQTQNKDGQIQMCHTDCALLDSGPLSKYLEEIDTWMEAHPREVVTLLLTNIDAMPVTQFGDTFKSTGLDKYVFKPGDKVAIDQWPTLQTLIDDGTRLVVFMDYHADTSKVDYILDEFQYYWETPFGETNADFPNCNIDRPQGVDPNGFMYLVNHFLDIELFAGIKIPNQIEAPKTNSLSSIDKQVNLCRGMWGRTANVVLLDWINIGEAIKAQSQYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHK6</accession>
    <name>A0AAD8XHK6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_792415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365033.1">
        <property type="nucleotide sequence ID" value="XM_060515758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHK6"/>
    <dbReference type="GeneID" id="85399656"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="563" mass="62388" checksum="E1EE1BC7360963F8" modified="2024-05-29" version="1">MLSSNPVDQAGQEEHQPANFRKMQSDIQSASKLLVAPEPTETDAIEHSITWPQMATSSDKQLATGDSVILRLAGLASRNSDLKELMRRVGNGKAEAQEVSYFQQFVDTTQDIGPRKWNVQSAFNDSKLPLLVQQNDDREVSQSPEPRIQSIIPLSEAQANSDAESLASGITWTSFLGGDIPYDNLAGMAGGFLFPVDESMQAEGSDNVFEDTGMEEIYFPPLPPTPKQDVPFTDSGYSSGINLDDLPRMELGVAATSDYDRKYPDAKTVYFRDSTVAIDQAQQYIFELSSTIHGNLGGNIDGDNWRLLSDRVSGLIKDFAIKIGLESSVQVNRDIMHFIHKRSREIATRLDSMILSVDPPAEDAGEGIEAKRDNMLLSDKMALWVSKATGTETPVNDDELFVGVTDVEETIDAPELSKYNKTVTESDSFKWLIESLRRELTLKRDFDESEGWDAQAAIVEDYMEQTWPSTWKTIFNLLQTVSRRPNGHVYADVLHDKTQVSVSSEHGILMMSLDGPAHTIAECGEQLAWLRASYANPPPQQGMSNTAQRIPVIMKMATLHVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHQ0</accession>
    <name>A0AAD8XHQ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_625492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363790.1">
        <property type="nucleotide sequence ID" value="XM_060508495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHQ0"/>
    <dbReference type="GeneID" id="85392394"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042236219" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="13738" checksum="CA460651A548305D" modified="2024-05-29" version="1">MCPRSARCGGLLSLRLCVCLSLSLDKSVARSRSISVVKPPRLLVICFSPPSVSTSIYQTQISGYLRHQDDGPSPSSLSHVSRKTSSTQTVSYFTLVSNNSLDTTLCYLTWQILRNHILGGILPPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI06</accession>
    <name>A0AAD8XI06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ORMDL family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_716813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368814.1">
        <property type="nucleotide sequence ID" value="XM_060511882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI06"/>
    <dbReference type="GeneID" id="85395780"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018147">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1728759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="179" mass="20617" checksum="6AFE520C08A8E7D2" modified="2024-05-29" version="1">MAEPGARRRRSSSILQVHYEPQETLEQISDQAVVPNLNANWVNAKGAWTIHFVLILCLKIFYDVMPGVSQETSWTLTNISYMFGSYIMFHYVRGVPFEFNGGAFDNLNMWEQIDDGAQYTPAKKFLLSVPIVLFLLSTHYTHYDLAYFSINFLAVLAVVIPKLPFSHRMRFGLFTDSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIL1</accession>
    <name>A0AAD8XIL1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_178180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367901.1">
        <property type="nucleotide sequence ID" value="XM_060501507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIL1"/>
    <dbReference type="GeneID" id="85385406"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="777" mass="84375" checksum="AD2DF2A6A7869F1D" modified="2024-05-29" version="1">MRLQKQQRRPSPDATMGTGQGKRPPPNQQQQQQQEQLRAHSPYPPQQRYYVQQPQSQPQPQPQYQQQFQPYQPPQQQQYYNPPRQPQYASRPTSPNPPQRKQTPQQQQQHQQQYPAQQQFLAELEVPTSAPRPTSPSTSSPNTTTSAPVPGTGTAQHGPVAYEMPADDVVTAKPTTQIHRKPHRIASASSVTAPSSSTSPPPASPTTAAAANKQDDLDQPKDEEKAQPPPQPPLIQANPWGFFLEDDLPSRNSDSPSPSKDDVPSVPPEEQKLSVKPLRIVKTGSTEESSGQGSRPSSSTVDDMTPKPLQLAAAVPARQDSPDTAQLKPAPLKLARPQPPVAEHRPSRTPSPANPAPPAANVPQLPYPAEGPSIPTPDSHPQHQPGIQPGPPTTLPFGIRPAGSPPPVSPSFAPSRLSPAPTGASAPPQQPQQSHPHPQPTHTQAAPVSPVFVQAALPPTLPVSSYFPQQPSYAKQEATSPNLSVHSPVASTPRPSTSQGIAQAPQHSPAQPYASPPPSYTQAMSQMHLSNTSPSPTQTQWLPPPPPPQGLSPNSTGVPPPLSPPPSQYPWSPNSIGPQSAPLQQQFTGYNMPPPVPQPTYVNGSQQFQPQPTQTPPPLPPRNSPPMPGTPQSGFGALTPYGGPPPPTRPNYQAPPPKSESRLFSSATARKLLTKTTELVDQTITPYLQDNKYYRPPYNWYQNQNPQNQNQNTHNQNQNYQNQNQNHQFPNRPQTATGYPAQQQQQYYTQQQSYAPSQPTYAHSQSSQQSQGVTRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIY9</accession>
    <name>A0AAD8XIY9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_537609</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366953.1">
        <property type="nucleotide sequence ID" value="XM_060503373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIY9"/>
    <dbReference type="GeneID" id="85387272"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1726898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="76" mass="8372" checksum="A01CEDA4A096BA9A" modified="2024-05-29" version="1" fragment="single">SGTLVGFAMLVAASVIFTYYSIWTLLMPFVDEGHPLQSFFPARVWAIRIPVILILLGSAVVGSFLGTVMIRSNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ51</accession>
    <name>A0AAD8XJ51_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_649821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367298.1">
        <property type="nucleotide sequence ID" value="XM_060510316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ51"/>
    <dbReference type="GeneID" id="85394215"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="161" mass="18266" checksum="A7B24A44DDB55EA8" modified="2024-05-29" version="1">MSSPGSSPDHGIGDAHLRINPLDNHIPRQSQLARFQQEHLQDGNTLVPLSHNPRDLKSAIDHHKSRATRAIKTFQQSFAKHKPDDATESSTDKPSSTEIVAHAFDVEEARNSFRKSQEGRELQVYSAPRHQCQDLYSHEDTREGLTREELRLWAVLVSNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL83</accession>
    <name>A0AAD8XL83_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369496.1">
        <property type="nucleotide sequence ID" value="XM_060507313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL83"/>
    <dbReference type="GeneID" id="85391212"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="104" mass="11627" checksum="109571441FADEE6F" modified="2024-05-29" version="1">MVYILLQHYRFTAPSERANEPTDDRSGRSPFLEGPSRVFASTPNLNSRADTTMETTPWRSVLLECLLESMEGLAQSSFPAGVDPERVTICLGEIVNLIELEIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL85</accession>
    <name>A0AAD8XL85_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_568897</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369433.1">
        <property type="nucleotide sequence ID" value="XM_060504131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL85"/>
    <dbReference type="GeneID" id="85388030"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21692">
        <property type="entry name" value="GINS_B_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1030:FF:000006">
        <property type="entry name" value="DNA replication complex GINS protein SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="10">
        <location>
            <begin position="61"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="11">
        <location>
            <begin position="167"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1729378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="221" mass="24873" checksum="C292F51A1F31805A" modified="2024-05-29" version="1">MDIDDILREVDPVSYSIPSETRDLQALTRAWVAERTAPELLEWPTGGLFERVNDRIKHQIEKVEDMTGDMDPKTNFALIVIQTELERFKFLVRSFLRARIAKIDKHALHYLSSPALRARLSETELAYATRHQALLHNHYLSSFLSSFPPNLQNLNDTAGNISMIDGPDLDTAVFIRMLRDTEVEGKGTDADGSVLAETGDILILRWSSAKPVVDDGNAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB2</accession>
    <name>A0AAD8XLB2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_31862</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369479.1">
        <property type="nucleotide sequence ID" value="XM_060502354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB2"/>
    <dbReference type="GeneID" id="85386253"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12841">
        <property type="entry name" value="TM_EphA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="59118" checksum="ACEF989D9114090A" modified="2024-05-29" version="1">MFSFPISIRFDDRLCGGDFVRCAITNCRVLTLTILDSPFLQYVSSRETFDQQMSSYLETTYVREKYQTLLGCSNVNLTNPDELYARFTATVVCNSIVQNSIDACNLTASNSRPVCADTCAEFAQSEALLTSDSSLCGNPGSNLVNQIRADFTNCALPAGSLSSSNCIQGIANEKENCGYGNSTVGLCSYCASGGINSTDTCCYNSNIDQRCAGVTLPSIFPTMTFAPPTATATPTPSNTAAASKGLSGGAIAGIVIGSVVGALLLAGLIFACILLAKRRRRGSQKGSVFNQPSPSRQGPSTVKIAPAQTTSGYEVLPGGRIARMSALESASDPAPVPPSRNSGPLMAAAAGGAAGYMTGRRRGDDPSSSEFGDSPESESRAGVLRPPPTNIRRTGSLSSSSVLADPQSPTSAGMSSPQGMASQQSEQLPFFKDYYSQDDIHPGDRVATLWAYQPRAPDEFTLERGDMLKIVGIWDDGWATGILVDERADEWEARRQAQRDSGVSNTSGRHQDNSPPVSGEIKAFPLVCVCLPEHWRKTIEGDVSTEGSSAHQGHSSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLX7</accession>
    <name>A0AAD8XLX7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase family C78</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_715991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369865.1">
        <property type="nucleotide sequence ID" value="XM_060511805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLX7"/>
    <dbReference type="GeneID" id="85395703"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="3">
        <location>
            <begin position="164"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1729810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="384" mass="42604" checksum="41C065B2C5822584" modified="2024-05-29" version="1">METFHPEEDNSHSSAPATGTPQEQYAECPIEGCGESIPLAEIDYHMDLHLEEDRQVAENPNSQAIIQSRQPNTSSVAAASSSHRESATEGQNANVEKRGKLLSLTAKSTGKEGEKRLGKAELGKYAHEQQMPDWLVSLLHKGGEVKSDGVISVLEQLLSQSKSTEYAFLCDPAVQHVSKLKKEGGFCGYRNIQMMISYIIGANAPGVDHFRGRLPTIFEIQELIERAWDLGINSQGRIETGGIKGTRKYIGTPEAQALFVGLQIPCTAQGFRDQEQGKSEAKLMIAVEQYFKQGAHRQGSKVTCTSLPPIYFQHAGHSLTIVGFEKQKHGPANLLVFDPVFRDPPALARLIGQTFKHKSADESLKPYRRGAKYLRRYREFEILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMX5</accession>
    <name>A0AAD8XMX5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">6-phosphofructo-2-kinase-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_398719</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000007">
        <property type="protein sequence ID" value="KAK1730244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370299.1">
        <property type="nucleotide sequence ID" value="XM_060502833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMX5"/>
    <dbReference type="GeneID" id="85386732"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000031">
        <property type="entry name" value="6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001280">
        <property type="entry name" value="Related to 6-phosphofructo-2-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF39">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="44"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1730244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="61120" checksum="B2014CFF207A4041" modified="2024-05-29" version="1">MDTLLTAEIAANAPRYRRKSSTFIDGIHDVPEDQDMAPAQLYSTMSGRLFHSGRIAIVMVGLPARGKTHICVSLARYLGWLGVKTRIFHLGDYRRATVGKGGIVPEDYFFPDASPQSVILRQKILKKCREDIYAWLNHENGQVAIYDAVNPTAAGRRALAKELAKHDVQTLFIESFVDDEAILRENARNVKISSPDFAGMDPDEAAKLYLRRIDMKIPVFDTMDEKELNYIKMINAGQKFFYNNVSFGYLSHRIVFYLTNLHIKSRTTYFVRAGVTTEEDSYKADAPLSEEGMAYAARMSETLLKHREQERAALVEKGGNAVPLRPLSVWTSTRCRTVQTADYLKNKGFKVRQRSQMSQINPGVCEKMSERAIRHLYPEEVEKHELDPYHHRYPRAESYHDLAVRLEPIILELEREQSDLLIIAHESVLRVLYAYLMHCATMDIPILKFPRDEIIEIIPAAYQNEAKRVHIPGVDPKITPGSPEDISIPVPGGGSGSGVASGNLSPMPGISSPAEPNVVVERPPEKVINTAAEMVADRQNDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNI2</accession>
    <name>A0AAD8XNI2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytanoyl-CoA dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_566542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370603.1">
        <property type="nucleotide sequence ID" value="XM_060503858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNI2"/>
    <dbReference type="GeneID" id="85387757"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1730548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="332" mass="36746" checksum="045E943CAC75E869" modified="2024-05-29" version="1">MASLTPNNHDYDHKDLPKTPATIHPSQSELLNARLSPRNLELAVRHLHRDGLVVVADVIPHADLDALNAKMVQDALYLRSLGDKGPFNYNLGNLQQDPPPVAEYFYKSIFTNAIATQITSSILGPRPNWTFCSANAAMPPSPDAKPQRQPVHSDADFAHPSHPFALVINVPLVKMTPSNGSTELWFGTHAPYTGTIIPSGLAAQQGAHGTRASGRITPPLLDLRRAVRPPSQPTVEKGSIVIRDLRLWHAGMPNTTPDVRVMLAMIHFAGWYRNPMRLQFAEDVRPFLEGETEAETGKSDLEIPVDWTTREEALKTYLGRGFGNSYDFDQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNK0</accession>
    <name>A0AAD8XNK0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-xylosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_646595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370748.1">
        <property type="nucleotide sequence ID" value="XM_060509986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNK0"/>
    <dbReference type="GeneID" id="85393885"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17415" checksum="66BB3BCA46F1A1C5" modified="2024-05-29" version="1">MATRHHHTTSGGIGNRRAARNAAFQEKMRQMRLPLAPLVQMSTGAVHPAFPTTLLNFWLLTEDQLDDLARFYHQRSPSPWSGQYPCPITWQSGLTLEEKRRKIGKFIGLRGCETPIRIRIKTEEQIMEEARQARLAEDEEALRRKMPWYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNK8</accession>
    <name>A0AAD8XNK8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_334689</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370827.1">
        <property type="nucleotide sequence ID" value="XM_060502437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNK8"/>
    <dbReference type="GeneID" id="85386336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1730772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26674" checksum="75DBBBAD026F9A9B" modified="2024-05-29" version="1">MIQQTSPAAESSHPNLRHGIQTSRTNAACCAEFALKSRKFLCKSHLWLGPPITHILVLCREAQAARRPGRFLSQVSITIRLGTARALKTAQMCAIRQLVLEHRRLHLCALRHSPLFQRRLDASKLAAKDWLRVLQRNGLCQVIFLARGKRYNAGVQDPVVDGLVVYDGLALPVLKLRHGLLALHDDFFDAIPEYKRLDRHGFLLANASSSANSLGLDLGVQNGVDEVDSRGSPHVETNSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNZ0</accession>
    <name>A0AAD8XNZ0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_335551</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370846.1">
        <property type="nucleotide sequence ID" value="XM_060502442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNZ0"/>
    <dbReference type="GeneID" id="85386341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000014">
        <property type="entry name" value="60S ribosomal protein L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049633">
        <property type="entry name" value="Ribosomal_eL6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01170">
        <property type="entry name" value="RIBOSOMAL_L6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="22467" checksum="D1958263F7F3F505" modified="2024-05-29" version="1">MSAKTESTTKKFGSSTRVVPAPSQKAQKWYNADDEPEAKKVRKAVRPWAPRQTLQPGTILILLAGRFRGKRVVLLKTLDQGVLLVTGPFKINGVPLRRVNSRYVIATSYKVDVSGVESKKIEEISAPKYFTADKAKKQVGEDAFFKQGEKPEKKEINSSRAADQKAVDKALLASIKKVDMLASYLASSFSLRKGDKPHEMTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPF5</accession>
    <name>A0AAD8XPF5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_293154</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371064.1">
        <property type="nucleotide sequence ID" value="XM_060502200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPF5"/>
    <dbReference type="GeneID" id="85386099"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042163686" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="22"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="382"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="445"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1731009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="482" mass="53352" checksum="7185F6CE56531E84" modified="2024-05-29" version="1">MRFPLSFAFLVAALLAVTAAAQKVNSITDAVAQLPTCAVTCILSAVKDSPCGLTNTTCICNDAKFESDTETCIVGTCSIKDTLHAKAVFETTCDKLVRDHSAEYVRLTWVLLGLTTFVVAARLIYKYFSSAELGLDDMFTLLAYLAVLPSFIINLVGIVPAGLGKDIWTLTSHQIESFGYWFYILEPMYFVQMGIVKMAILCFYMRIFDRAGLGKLLWGTAAFNAVNTFVFLMVGIFQCTPIQYYWTRWDGEQKGTCININAVPWANAIISILLDLWMLYLPLSRIRTLNLHWWKKLAVTLMFCVGTFVTIVSILRLQSLVRFASSLNPTWDQFDIAFWTCLEVPTGIICCCLPAIRLILIKAFPKLFGMLTKRYDTQKYAESPSSAADGSRSTNRMSRPLGDSSTTELQSALRGGKGIVCTKQFALETHDTSSLYAMQDLESGSAKNSLSQSHRSTSISHTSSPVSDYGASGRKQSGPSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPY9</accession>
    <name>A0AAD8XPY9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_565205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371347.1">
        <property type="nucleotide sequence ID" value="XM_060503724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPY9"/>
    <dbReference type="GeneID" id="85387623"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000013">
        <property type="entry name" value="Cation efflux family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000010">
        <property type="entry name" value="Cation efflux family protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF15">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="50"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="367"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1731292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="392" mass="42095" checksum="F0BABD67ABE19CCF" modified="2024-05-29" version="1">MSATTTATMTANPPQSRKSHGHHHHHHHGHDNVYLTSANKNDAGVRITRIGLYSNLGMAFAKGAGGYAFGSQAMIADAWHSLTDLASDVLTLATVSWSLKPPTEAFPTGFGKIESLGSLGVSSMLLGGGLFMCWSSLITLHAHLFLDPAAAAEAIAHAHHGHSHGHGHATPSLHAAWLALGTIAIKEWLYRATMKVAVERKSSVLASNAVHHRVDSWTGIVTLLAILGANFFKDATWLDPVGGLMISLLVIKAGAENTLSSVYELADRAIDDEVKGDVQKYALRSLSDVTDGHEVDVRNVSGVKSGQNYLVDIDLAVPGAWSVEAVREVEDQVRTLVGAKVRGVRRIKVRFVPKEAEVARPFDEFIPGEANREASEEADDHSHTNGNGHKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQ54</accession>
    <name>A0AAD8XQ54_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_688053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371424.1">
        <property type="nucleotide sequence ID" value="XM_060511287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQ54"/>
    <dbReference type="GeneID" id="85395186"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="379" mass="43306" checksum="8465A8DD8F82EAA4" modified="2024-05-29" version="1">MVAAIFNKLVITAAGDFPSGCSREQVVQWAKMRKGKFSSRLDETTTHLLFTDAEFKSKKKHHRIKEAERRSNTKGARKIHIVSWSWFAKSCCDNKKLALKEYRYDAMKIKEKRDAQAETERARAAASAYRWISTESYSVAKDLTSFEYKVDLFRSSENEDGTLHEKYELYFFRSHSSRPHMYWFGAKLFHKKDNGKWVERGIERPSPCCSTFRNEYDRFRKFFELKTKIRWADRVARAGTQEKTAFSYSPPTGGKPVGCRMVGALYNKAVRSNKKMLRRYAELFGDELPSDIQIEDACNDILKDIVDEVCATPKMDAEEENGVNEVTMANMNLGPGKNDAVDSDMEGHAEIDALSDPGVMAQSSSEIEDIVMEGHVEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQA4</accession>
    <name>A0AAD8XQA4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_725657</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371635.1">
        <property type="nucleotide sequence ID" value="XM_060512739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQA4"/>
    <dbReference type="GeneID" id="85396637"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054464">
        <property type="entry name" value="ULD_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886:SF1">
        <property type="entry name" value="NACHT-NTPASE AND P-LOOP NTPASES N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38886">
        <property type="entry name" value="SESA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22893">
        <property type="entry name" value="ULD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="297"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="544" mass="61065" checksum="E3EFB906BDDD0480" modified="2024-05-29" version="1">MSFGWSTGDIIVALQLFNKVRIALKDSGGSRTEYQNAIAFIDELSTTLRTLDDIQTTSPHPDLLQDVCSHAKRLRIEVDLFLKTIQDEYGESLGPFSTSGKTRILQNKIRYAISTSKNVQGLRVKIGPELSTLQLKISHHVLLVCANLPSDIERQMNHATKAAFKSFCSNQEIGDILQTVLSLGNKIDTCHEQTSKVLSIIEAVHNKLQAQERGPLIQLESWPESLPFTRDTVAENHNNLKSPLSILQNSQQVVSGLSGILRAAICLLSFSMVALYRKAVFTISKRSTLIPIRPSLQSGIKFIDALGRTSTLPYDCGRSWEIFEKTIHVWFQGCPGEDLVRQGFYCVADARTPSEFFTQESWSCCVKDGMTIQMSVIINNCMECGSRVTSDDVNDYALCSSCNRQHIVVTRDAFLGASSDLFSLGIKQAQNSYLGKTTSFSPQNSIRKQLKHAVFYNPPSYRSYQTTHEDSGPLDFGEIDTDTESHCKCFAMAEETHGELSQCYVCYLIDLEKDLLHVPYLRKNWGCPEPFLTNGFQHWSEFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZG8</accession>
    <name>A0AAD9CZG8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vps52/Sac2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_569246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369139.1">
        <property type="nucleotide sequence ID" value="XM_060504169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZG8"/>
    <dbReference type="GeneID" id="85388068"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="153"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="337"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1729084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="658" mass="73450" checksum="3232DAF3E94D8214" modified="2024-05-29" version="1">MWLDRLAAQSNSSPSASQPGSRPYSPLPRRTSSSPYVTSQRPGITPRGSQLSLVSNDSSNSFLASRRVNGSGLKQSQTTYDGPDSVEILGQILDTAPTSEATTITISENDLELDFQFEGLSLRELASSDEIDSSDADSYRRQTAEEFEASKAQFEDLHRSIAACDGVLGSVETNLTSFRNDLAAVSADIESLQSRSAAMNVRLDNRKAVEKAFGPVVEELSVSPHVVSKISEGQIDETWVKMLAEVDKRASAYKKSVSNQGESKAWADLGPLLEKLTMKAVERIRDFIVAQIKALRSPHINAQIIQQQNFLKFKDLYTFLHKHHATLAEEISQAYMNTMRWYYANQFGRYQRALEKLKLHILDKNDVLGHEEPTRRATVLSATKPAGPPHDAFNLGRRIDLLKSGNAAAISSYLAEEDQTTHYLEVPFRNFNLALIDNATAEYTFLAAFFSPPLSLQAVSRQFNYIFEPTFALGKTLTRTLTAESYDALGLLLSIRINQHLAFELQRRKVPAVDGYINMTTMLLWPRLQVVMDHHCESLRQLMNTLPTKPRAADQNKLSAAPHLVTQRFGQILQGVLALSTEAGDDEPVVTSLRRLRSEAEAFLTRYSQSFSDKRKRERFLYNNYSLISTIISDVGGKLGTEQQEHFEGLKAAFQEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0R0</accession>
    <name>A0AAD9D0R0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_423652</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370173.1">
        <property type="nucleotide sequence ID" value="XM_060502996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0R0"/>
    <dbReference type="GeneID" id="85386895"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1730118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="621" mass="66260" checksum="D6F7938612458E3D" modified="2024-05-29" version="1">MFASDSFLPSAFTDHDPNMPPSAVISPLSLNRMASSCYFDNRSAATTSATGNSIYSPRSSGAVRYPPQTQSLLSPHLHPNGVNGTNGYRETVSNDQVPRVVSPTHFEQFEGHNPSAFASTARVSPNGMPHPRSVSADAASAPASAQIIRRLAQQNARIREAWEAERKYMEANRERVEEVYKEERIIMEDERLAWEAEKNDLTEQIRRLKEQVAAIDNDKIRLQGALQRAELEKAGKVAGVTVAIPGTGTRGGADGSTELSFPGFSSQPNDARFGLSNGTAQRRPTNGSSSASVSPAQIRSHFISPGSSRISPSRQPESSPFIPLNPKMQPTTADPVDFLGSPKDEEPVPIVDIQIINPQLEGVPLKAPAIQKSTFIDSGMTPPENSKTSSRAVSPPGESGKSRRSPTQEHTLEVLAAPEPARLVMHAGHTPSHSLSVLGTAPGTEVATVADGSGGSTPTLAPTDMSSNPATLYDVRARADSSDLQDDAYGGTEEPLPTLEAADDVALKGPLMVRNIPAHDEIFFKRLSEKLEGVSSGADAVPTCMKAPTPELVEEPLEAKENLFVAKADADAASDKGSTSDRASSSDRDDVSESQSKLEEIDIPLKLKQSTNFGAPLGAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D0V3</accession>
    <name>A0AAD9D0V3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Family 43 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_567164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370248.1">
        <property type="nucleotide sequence ID" value="XM_060503929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D0V3"/>
    <dbReference type="GeneID" id="85387828"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18619">
        <property type="entry name" value="GH43_CoXyl43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1730193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="326" mass="36963" checksum="EB930C60CF1D5C0A" modified="2024-05-29" version="1">MAPLINHLYTADPSAHVFNGKVYIYPSHDRETDIKFNDNGDQYDMADYHVFSTSSLDPLEPVVDHGVVLKTEDVPWVSKQLWAPDAAYKDGKYYLYFPARDKQDVFRIGVAVSDKPEGPFTPDPEPIKGSYSIDPASFVDDDGQGYLYFGGLWGGQLQCYQKGNEVFEKQWLGAQEPSGEGAYALGPRVAKLTGDMHQFDGEVQEIQILAPETGKPILADDHDRRFFEAAWLHKRDGLYYFSYSTGDTHYLCYATSESPLGPFTYGGRILEPVLGWTTHHSIVEFKGQWWLFHHDCELSKGVDHLRSVKVKEIFYDKDGKIVTEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1L4</accession>
    <name>A0AAD9D1L4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_747858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369891.1">
        <property type="nucleotide sequence ID" value="XM_060513518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1L4"/>
    <dbReference type="GeneID" id="85397416"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="123" mass="13786" checksum="AB41C391BA851C9E" modified="2024-05-29" version="1">MSATVTENPVTTTIQRDYLHDYQIRLTGGVEEAFARGNADAPSPVAVNPPGWYDQHRQVPPYRPANTNMDIADRPWGSNGIESAFVFVMLNGCWLQGVTNWLWRATGGRVNKDIFRFKVGGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1X5</accession>
    <name>A0AAD9D1X5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PQ loop repeat-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_603002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370131.1">
        <property type="nucleotide sequence ID" value="XM_060507201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1X5"/>
    <dbReference type="GeneID" id="85391100"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="113"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1730076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="338" mass="36314" checksum="DAE391562B4E2FF6" modified="2024-05-29" version="1">MASVAVTAFAALSSTPKVEEALSGIFGSISLTAWICLLLPQLLTNYKSQSADGLSMGFLIIWLIGDVTNLMGALFTHLAPTAVALASYFCFADLVLISQCVYYNTKNARHASSRRRSSAPVTATGANPTEAREDEPLLAPRRRSSSAAAGLPGSQRRHAHHEESSLDPLRKMVTGEDDTPDSNPWLHNTLSILAVYLVGAAGWFLSYKAGAWDAPDSDTGAGSGAGSPAAADGTWEKIGLALGYFSAVCYLCARIPQIIKNYREKSCEGLALLFFLLSLTGNLTYGASLVAFKQDRAYLLNALPWLLGSLGTMVEDFVIFGQFHMYATKREGKRDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D2P9</accession>
    <name>A0AAD9D2P9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_646074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371628.1">
        <property type="nucleotide sequence ID" value="XM_060509916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D2P9"/>
    <dbReference type="GeneID" id="85393815"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF177">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER MCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="136"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1731573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="529" mass="56101" checksum="3AC8A92338019193" modified="2024-05-29" version="1">MDPEKVSTAHQGDHITPEPDYSSYDYPLPSKPESAAHNGAAAVIGNDLIPSVSNAVAGAGGANYHHQCSSDFINNSNKNNNNATYSKEAGGDGGEGGAGDTTDDDDNGNYIHRTDTAGAASTTAAEEETYPEGGLRAWSVVLGSWLALFSALGIMNSIAIFQTYVATHQLKGYSEGTIGWIFSVYTFLCFFGGIYIGPVFDQYGPRWLVLAGTVCLVIGVMLLSICTVYWHFMLAFGILCGLGSSLVFTPSIAAVGHWFKRRRGFATGMASTGGSIGGIVFPLMMKSLFPRIGWGWTIRAVGFICLALCGASNFLIRSRLPPARNASPHPDPRIFRSAAFSLTTAGIFLMEFALFIPLTYISSYTLSQGFSESFAFSILPILNAGSVLGRALPGWWADRAGPFNSNMAAIMLSVVACLAVWLPAGSTAAGVIVFAVLFGFASGNNISISPVCVGRLCKTQHYGRYYSTTYTAVSIACLIGIPIGGEIVTATGGQYWGLIIFTGLVYVLALVALMAAKFVCVGKVIWGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3Q1</accession>
    <name>A0AAD9D3Q1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter transmembrane region 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_645888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371990.1">
        <property type="nucleotide sequence ID" value="XM_060509893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3Q1"/>
    <dbReference type="GeneID" id="85393792"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="173"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="527"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="788"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="747"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="817"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="829" mass="93251" checksum="1DB1D59138162FA7" modified="2024-05-29" version="1">MAEQSTLRQSAAEEALAAFFEKYTTLIRNRLRSTSRTTRLLGTLALAASIVLSAAGGRRWWRQRREEKEQGRKLVRTNSWLHNKDGSRTIYVPYKDGTSKVVIQTTKPLTFEAHRRLFLNPPRVSGLGDGTVPSAQTKPGLNLAFLHQFLSLMSIMIPRWSSKEAGLLLSHSVFLMLRTYLSLVVARLDGEIVRDLVAGQGKAFLWGLVKWCGLGGFASYTNAMIKFLESKVSIAFRTRLTRYIHDLYLNNNLNYYKLSNLDGGVGQGADQFITQDLTLFCAAAANLYSSLGKPFVDLCVFNYQLFRSLGPLALTGLLSNYFLTASILRRLSPPFGKLKAVEGRKEGDFRGLHARLIANAEEIAFYGGADMEKTFLNKEFKSLKNWMEGIYMLKIRYNMLEDFILKYSWSAYGYLLSSLPVFLPAWGGLGGAAELAENAAKGSRERGRMKEFITNKRLMLSLADAGGRMMYSIKDLSELAGYTSRVYTLISTLHRVHADAYFLRGQQNELYSLSDVQGTIQKGFDGVRFENVPVVAPSLWPNGGEELMDSLSMVVRRGEHLLISGPNGVGKTSIARILAGLWPVYRGLVSRPKDIGQDGIMFLPQRPYLSIGTLRDQVIYPDGHHDMREKRKSEDDLKRILEDARLGYLPDREGGWDTRKEWKDVLSGGEKQRMGFARVLYHEPQFAILDEGTSAVSQDVEGLLYEVCKEKGITLITISTRASLKKYHTYNLILGGGERGDEWEFERIGTEHEKMQVEKELQDLRERLEQVENWKARRQEIEEELSKVWVAGGDELDPPSYAESESDSSKGKGKETASLSSTQEILGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U755</accession>
    <name>A0AAD8U755_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_134584</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000176">
        <property type="protein sequence ID" value="KAK1709996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358692.1">
        <property type="nucleotide sequence ID" value="XM_060501239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U755"/>
    <dbReference type="GeneID" id="85385138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF10">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042059176" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="9">
        <location>
            <begin position="16"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1709996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="232" mass="24560" checksum="DD533907E92ED822" modified="2024-05-29" version="1">MLFSTLSALVLAATASAHIVISYPGWRGNNLITNDTFPYGMQWNYPCGGMHVTQNRTYWPTTGGALAFQPGWFQGHAQAMMYANMGFGSDGPDGGPLNMSFPMVPVFQILGPSKNPYPGTVCLPQVPLPANTTVKAGDHATIQIVELAVHGAALFSCVDIEFAEPGDPKIGKVNETNCFNSTDIGFGDVYTITTKESGAEYVQGTSAGARTTTSFSVAGGLPLLLGALWILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7R7</accession>
    <name>A0AAD8U7R7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_644158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000242">
        <property type="protein sequence ID" value="KAK1705457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357613.1">
        <property type="nucleotide sequence ID" value="XM_060509732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7R7"/>
    <dbReference type="GeneID" id="85393631"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1705457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="281" mass="31204" checksum="EAAEE3006CC48C73" modified="2024-05-29" version="1">MIGDCDIIIPKGLHLVSLPRLWDKIIPFWVANASIHSKLYNLLYSRSAQLISQEDLSDRADNLLADLKLIEPVGLVNPTMVSSDSTQPTTKLEAVLAKSAKVMYHTTATLISRARTSRASVPSFSPDCLAYARATIDAHLECVPLMSGDLHVVNLYLHWRLLQTPFIPLLVVFCHIVETQDTSDAQRLKSFADSLEQGADLSPSAKDFYDITQELSMIAEKHIETSSKQDWASFPSLSTLGLSQFYPANAMGDNYHLAAEHVQSNQDMEMIFGGEQVMGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8K1</accession>
    <name>A0AAD8U8K1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_759162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000367">
        <property type="protein sequence ID" value="KAK1701586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357007.1">
        <property type="nucleotide sequence ID" value="XM_060515139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8K1"/>
    <dbReference type="GeneID" id="85399037"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148345" evidence="1">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="102" mass="11308" checksum="91238CDEFF3CE1E6" modified="2024-05-29" version="1">MAAVFKTFALAFLLIQGAQSKDHSSHNCCLLTAEGWIPRNDWTKAVCEERWGSVATFDGVKCIQKPGNVISGDDFFTACKLYGYINGYQQWERGAGYRGTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA25</accession>
    <name>A0AAD8UA25_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_756283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360297.1">
        <property type="nucleotide sequence ID" value="XM_060514726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA25"/>
    <dbReference type="GeneID" id="85398624"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042217281" evidence="1">
        <location>
            <begin position="23"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="249" mass="27742" checksum="49D597FC2BA27891" modified="2024-05-29" version="1">MLPTHTLTSFLIWAEIASPAKPVTCPSSSELRVTIPPSHQSPSNADYKSLDEVHDALTHCPNITSLNLRVGEIGCVGEPDRWSLPLDPAGTSRYFPVLDTLSLEKYQFYDTDGDYLRPLRGWTHLSAWIWSGGAFGWVKWGLLTEDQRSVNNIELWLDAMDFSKIRNLSILDYDGPLETLVESKLPQSLPSLRTLRLERSTTVDFALSLPPHSLHSLSWLDAGQNQSIAPSSITMAALSLTWNGVRQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAA6</accession>
    <name>A0AAD8UAA6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_656701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359282.1">
        <property type="nucleotide sequence ID" value="XM_060510896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAA6"/>
    <dbReference type="GeneID" id="85394795"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1711958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="15098" checksum="89296088938397D6" modified="2024-05-29" version="1">MRYREYLDAYSSPDENAKSPFYAEDCQFQFDDLKLSGRDPIMAMFAKGHVGVKEELRPIHVLETDKQILAELDACFMPFEDTPGNLIHPFRKYQPISFRFFASYEIRDNQIQSFRLAHWPQPTVIEPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UB21</accession>
    <name>A0AAD8UB21_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_81249</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359717.1">
        <property type="nucleotide sequence ID" value="XM_060515938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UB21"/>
    <dbReference type="GeneID" id="85399836"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="41"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1713391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="351" mass="38842" checksum="5D01576C3C5191C9" modified="2024-05-29" version="1">MSEPSFTSANTVAPAATGNLVYLHYVVFGVGYGVSTLLLLLRLYSRYRYSRLRLDDMLVVFSWVFSSAMQILMIVAISMGTMCFPRVSIPDDRFRIYVESQLSYNAAPAFMMSIGCAKASILCLYLETFYVDEWLYKAARITQGVLITITVTITLLLYLSRLPSLSLDAVALFLATAASNIIMDLVLLILPIRPVFRLQTSLGRKLRLTGFFSLGLITTVTSILRLYLLSKIQQSEDLTWDAAPANITSFLEINLLLICACVPAMRQFFRALKPDSPIVNQSTFTNRASGTTQSRLDSSSQVQLRESQDSIVELGIIASRSQSSGAGSARADSAWSEPVHEKKVLSASLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBS7</accession>
    <name>A0AAD8UBS7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_632678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361257.1">
        <property type="nucleotide sequence ID" value="XM_060508986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBS7"/>
    <dbReference type="GeneID" id="85392885"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="21867" checksum="FDF06CF4F7788AB4" modified="2024-05-29" version="1">MEMLLRILFISLPHRHHGLFQTASGVTTHAANHSHASLAPQVSGRRRNRGAPKTCGGVGTGKRGGRARRRQPGKRNELPRTRRKSTTAMQEILRSNTYTMHRDPPNPRPALPYHPQLPVFGTPTRNTPVSVRIDRQSPCSAKSRSYRISRALFCFPPCLIFGVVIHLPCALQMVTVDSAGKSTLSSPLCSAALLPLLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC32</accession>
    <name>A0AAD8UC32_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_588594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000128">
        <property type="protein sequence ID" value="KAK1714930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360073.1">
        <property type="nucleotide sequence ID" value="XM_060506152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC32"/>
    <dbReference type="GeneID" id="85390051"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="251"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1714930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="69704" checksum="010035C1B4B7E316" modified="2024-05-29" version="1">MAAKPQEVFKLLFQQGKLVLDNPQKVTHIHDRGESFRLKSEQRNPPSRRTIGASMRPEEFRFEHDVIRIIAEELDEAAAMVPDLLEPDKDFIPRRTFEQIMTHSRVLSAVHVLKCFKGVQDKDQLAREIRYGSVDGSKSPCVKLLAILIGIDRAEDMSIHMWTDELRDSCLPLKKVPNDRRRALQCRKHKEHRLLNSYRRPEDRNRFSQWTYSMCSPFIKWEHGTHQHYLLDTGDVFPMEVMAKVEEEDRKSDSGGNSYGGFSEVYKVKIHQGHSDFGVHGIRHPQGYFALKKLTSHSRDSFNLELSSLVSTAQNYQKKHIIQLLATFEVKNAATRESTFYLLFDWADGTLNKFWQSNEALVRDKRHCKWMATQFYEVCEALRYVHNDREPTVRYLEDRDSNKQLYGRHGDIKPGNFLWFKSDSFPGLLALADFGLGRLHTQVSRSKQDPNSLERTATYRCPEFDLEFGLVSPRSDIFSLGCVFLEYVTWFLLGLEDVEKTFPDFRLEQDKHGFDSDVFFSIKDKKAYLKSSVTKWITKLKNHRDCSWYLSDLLDVIRDRMLDPESTTRIPSSLLSKKMKDLLSTCTVDPDYYLKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCT1</accession>
    <name>A0AAD8UCT1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Squalene synthase</fullName>
            <shortName evidence="15">SQS</shortName>
            <shortName evidence="15">SS</shortName>
            <ecNumber evidence="4 15">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_584533</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 (2E,6E)-farnesyl diphosphate + NADH + H(+) = squalene + 2 diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:32299"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 (2E,6E)-farnesyl diphosphate + NADPH + H(+) = squalene + 2 diphosphate + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:32295"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="4 15"/>
    <dbReference type="EMBL" id="JAHMHS010000090">
        <property type="protein sequence ID" value="KAK1720301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361812.1">
        <property type="nucleotide sequence ID" value="XM_060505765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCT1"/>
    <dbReference type="GeneID" id="85389664"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055056">
        <property type="term" value="F:D-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000003">
        <property type="entry name" value="Farnesyl-diphosphate farnesyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1720301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="464" mass="53471" checksum="782B8A22602151F6" modified="2024-05-29" version="1">MGVIYYLLHPNQLRSIIQWKVWHDPVHHRDPSKEDPTLKSCFEFLNKTSRSFSAVIQELNPELLVPVCLFYLVLRGLDTIEDDMTLDIKEKEPLLRQFDKYMETDGWTFTKNGPNEKDRELLVHFDDVVTELKKIKKPYYEIIKDITIKMGNGMADYALNAEHNENGVATIKEYELYCHYVAGLVGDGLTRLFVEGNMANPKLLERPALTESMGQFLQKTNIIRDVHEDYLDKRRFWPKEIWSKHVDTWDDLFKPENLPKALECSSEMVLNALKHTEECLFYMAGIKDQSVFNFVAIPQSMAIATLELVFRNPAIFSSHIKITKGDACYLMTKSTQNLQIVCEVFRDYTRRIHKKNDPRDPNYVQISVQCGKIEQFIDSLFPRQDPKLLGDAAKQKERGQPGMDAGEAFVLGGMVLLTLFFVSGLMIGTAWFFGARFDSLWKTDSIYWPGSETGAATPIEHKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD38</accession>
    <name>A0AAD8UD38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_105377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000150">
        <property type="protein sequence ID" value="KAK1712243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359361.1">
        <property type="nucleotide sequence ID" value="XM_060501050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD38"/>
    <dbReference type="GeneID" id="85384950"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="274" mass="29361" checksum="3337E30B93F8B0AA" modified="2024-05-29" version="1">MPSRTSIEYLLAPTAATPTLCNETEAFQEDIIGPHTPPTGAMSPSIDFQRHQADMDQYSDTRGHATSACSLLSPAKLTSSGQPTLNDMVSVYTQQSPSVTFSSMTLQEQMFSGYYNAGSGLSAQMCPICLHIAFMNPCFLRSMCGQQYFEVPSAAVYDPAFLHASHDCYCGWCAGCGICAFKPAEHSIPSGSYTESSHLQTGFTDGYLTNAADSSHAIYDGPLSPSVYDLDGQPISQQGFVLGNVDDGGAVGENVRPTTLPVSVFPEQITAWKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDM5</accession>
    <name>A0AAD8UDM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_545000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359643.1">
        <property type="nucleotide sequence ID" value="XM_060503442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDM5"/>
    <dbReference type="GeneID" id="85387341"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1713317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="135" mass="14004" checksum="3958E01C4D51C6C8" modified="2024-05-29" version="1" fragment="single">IIVAILGLIPLAVAQRCNADNCARRVTGTFRAAGVPDVTNRGLDCSSYMQTAVIPDTFTSTVTTTIYTDNIPTNPTTTFSQSTTRAAITQSPTSVPSYAAVSCTSTGAYSSACSCWGYIPSIKTLPAPVAIVTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE33</accession>
    <name>A0AAD8UE33_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA/RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_637457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000138">
        <property type="protein sequence ID" value="KAK1713378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359704.1">
        <property type="nucleotide sequence ID" value="XM_060509312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE33"/>
    <dbReference type="GeneID" id="85393211"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005697">
        <property type="term" value="C:telomerase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000202">
        <property type="entry name" value="Unplaced genomic scaffold supercont1.7, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018834">
        <property type="entry name" value="DNA/RNA-bd_Est1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045153">
        <property type="entry name" value="Est1/Ebs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696">
        <property type="entry name" value="SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15696:SF0">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN EST1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10373">
        <property type="entry name" value="EST1_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding" evidence="1">
        <location>
            <begin position="149"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="492" mass="56814" checksum="60392F8087AFF00A" modified="2024-05-29" version="1">MIESQCIEVDNAQSSNNETNPKLNNEQWQALIGLHRTLLHEHHDFFLASQHPLASPALRRLASKHAMPERMWRHGIHSFLELLRHRLPASLEHMLTFIYLAYSMMTLLYETVPTFQNIWIECLGDLSRYRMAIEDDDLKDREVWTSVSRHWYSKASDKAPQTGRLYHHLAILARPNALQQLFYYTKSLCVPLPFLSARESIMTLFDPHLNGTQTRLQEIDAAFVRAHAILFSGKNTEQLSSSINVFIDSLNNHIAHHTCRWLESAYHISIALSCSLLEYGSESNPIMRAIQSGRADDADVPMKGTETVGAPTQKFLDALDFAARTHNVVLRRFGDESIRPYLHVTLSLLQHLSHFPAAMELVEKKMPWKLIALLLNTIMHTNMPAEAYKIIESEDFPRPDKGDPRPLPDDFAQRGLLWVDEYYPDDWFSTTKVDDDEKYLESSSMMSERSIRCLWLGCRLATSGKWLTYREGHFRATCEASEMSFKRKPWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF76</accession>
    <name>A0AAD8UF76_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sterol 3-beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.173</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Autophagy-related protein 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_587120</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a sterol + UDP-alpha-D-glucose = a sterol 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22724"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15889"/>
            <dbReference type="ChEBI" id="CHEBI:37424"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.173"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:22725"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61836"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16933"/>
            <dbReference type="ChEBI" id="CHEBI:52973"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61837"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000112">
        <property type="protein sequence ID" value="KAK1716760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360690.1">
        <property type="nucleotide sequence ID" value="XM_060506010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389909"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13215">
        <property type="entry name" value="PH-GRAM1_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13216">
        <property type="entry name" value="PH-GRAM2_AGT26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000303">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000560">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048066">
        <property type="entry name" value="ATG26_PH_GRAM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048065">
        <property type="entry name" value="ATG26_PH_GRAM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="17">
        <location>
            <begin position="315"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="86"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="495"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="584"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1402"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="510"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="632"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="665"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="1408"/>
            <end position="1417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1716760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1468" mass="164669" checksum="55E5A6407909CCF4" modified="2024-05-29" version="1">MASPAPAGAASVSFGEDDVKKRVGKKLQKKRHESNTPTMELPERLKEGDDSREEDLVPQQGPPMFMNMNQSIFGLIAAAGSRVDFHDRFESSDEESGDEDEPTRRHGADKLEGGDDKVHGIGHLLHRKQRRQNDSDLSKTTVLKKDSSSKTEKHRRKISGSKLLRSLPALPRLPRHKSKKEPSKLEPTSEEASDTSEPSPSQPADDTREDDDQDGHRLAPVMSRMLEAKAEMSARPSFDVDRRSSDQLNYSDSGDSNSTALARRLQDIFEFDHPEAVIEAEYPCWLLQSVLLQGYMYITAKHICFYAYLPKKAHEVVKSGYLSKSGKRNPKYNRYWFRLKGDVLAYYKDPSNVYFPSGQIDLRYGISASVNNNKDGLTFTVVTHHRTYHFRADSAPSAKEWVKSLQRVIFRSHNEGDSVKISLPIENVIDIEDTQMLEFADTCKIRVIDNDETYAIDEYFFSFFSFGKDAISVLKILIEDASSSAKDAALLKAAQAQEEQERQEKQPVPASARSSMSVSRRIAPPKLRTTKLPDAVKATLSPLSAHSPSALSPRASMDAARASFDAFRGFRRRSLDLSTIIRDSSPRRSFSGNRRSMSRNRLDDSRHGIHKQGSTDSYVQSSMEDPSYSGMVASSNEDPSASQILRGSDVFQNPTVRRSASASRTELEKNQRRDDRSPPALAAYSGQHAATTGSINDGDKPPVTPTLQSITKMGAFPLQRVGAFAQYLNSTSGKLGSMLATESMGYVEKVSGMWRGGRKHYDAPPEIKTDDEDLYEDAEGKIQTSMDRFRAHFALPETEKLQATYFGYILRVLPLYGKIYISDKSFCFRSLLPGTRTKLILPLKDIENVDKEKGFRFGYSGLVVVIRGHEEVFFEFGQAELRDDCAVTLLQSLETTRYLKESGDLDLDEKEEEENAMAERDALKEARQVEEFHDHELRLPKEGSGVSDAPTILFDDPKASFLNFKPPHSMKITCLTIGSRGDVQPYIALCKGLIAEGHKPRIATHAEFKDWIEGHGIEFAKVDGDPGELMRLCIENGTFTWAFLREANSMFRGWLDELLVSAWEACQGSDLLIESPSAMAGIHIAEKLSIPYFRAFTMPWTRTRAYPHAFVMPEYKMGGAYNYMTYVMFDNIFWKATAHQVNRWRNNTLKLPNTSLEKMQPNKVPFLYNFSEYVVAPPLDFSDWIRVTGYWFLEEGTDFKPPQELVDFIAKARADEKKLVYVGFGSIIVNDTAKMTQEVIDAVQKADVRCILSKGWSDRVAKQGEADSAKDEPIIPPEIFVIKSAPHDWLFSQIDAAAHHGGSGTTGASLRAGIPTIIRPFFGDQFFFGGRVEDIGVGICLKKWGAVSFARALWEATHNDRMIVKARVLGEQIRSERGVENAIQCLYRDMEYATSLIKRKAGKHAHAEEDEDEEAEESWTFIGNDEPDPDMTTKKLSEMGTLPGLPGDKPLGNRVMRVSPSPSQQPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFC3</accession>
    <name>A0AAD8UFC3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BDZ83DRAFT_630904</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361907.1">
        <property type="nucleotide sequence ID" value="XM_060508864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFC3"/>
    <dbReference type="GeneID" id="85392763"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="15">
        <location>
            <begin position="121"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="16">
        <location>
            <begin position="429"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="17">
        <location>
            <begin position="533"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAK1720396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="627" mass="71183" checksum="E8BEC23F22844592" modified="2024-05-29" version="1">MKAEELQTLPTALAGDFKSIEPHLRALDKHLTLRTFVEGYSLGETETKIWQTLKLNKVAMGFIRKGTMANLTRWFTFVEVTYPEIQAETNAVDAERKAKVVAASKKGASYSLALQNAEAGVVTRFLPEPSGYLHIGHAKAALLSDYFAHEAYKGKLLLRLDDTNPAKESEEFQDAIVEDLKMMGITPDSLSYTSDYFDYLYETCVRLIKEGHAYADDTEQETMRNERTDGIESKCRNRSVEENLRIFEAMKEGTPEGLNNCIRAKISVDNVNKALRDPVIYRCNVENKHHRTGDKWKIYPMYDLACPVVDSHEGVTHALRSTEYTDRNPLYQWFIDTLKLRQVYMHDFSRINLVRTFLSKRKLAKIVAQGTVWGWDDPRMPTIRGVRRRGMTIPALREFIIKQGPSRNVVNMDWASFWNINKKVIDPIAPRHTAILEKDAVKVKVTGADAPATPRTEDKPKHPKNPDVGTKKVVFSNELILDQADVKSFKKDEEFTLMGWGNAFAREIGATDPITDLSVELNLKGDFKTTEKKVTWLSTAGTKLVKAELWDFDYLINKDKLEEDDVLEKVLNPNTSTMETALCDAGVGELKKDDIIQLERRGFYRVDKGLDEGDVVVLFNIPTGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGD5</accession>
    <name>A0AAD8UGD5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_636106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000125">
        <property type="protein sequence ID" value="KAK1715057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360200.1">
        <property type="nucleotide sequence ID" value="XM_060509229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGD5"/>
    <dbReference type="GeneID" id="85393128"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05198">
        <property type="entry name" value="formate_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="6">
        <location>
            <begin position="52"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="7">
        <location>
            <begin position="176"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1715057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="40889" checksum="97C1FDD6226DF5F4" modified="2024-05-29" version="1">MTDPATEVKKPARLPSATHHVIVKLETIHVPPPEVNDGDLGAGVTHEVIGYEYTRPSESAVAAARAWPASVLITTTVPINRETLGEAPHLKCIITETVGTDHIDLEECRRRGVTVIYSPNATVEAVSEHALGLYFSSRRRFVTLHNTMMDHAEGRPNPWRAEGSMSSLLLNSEGRPPHTCGNEVVGMIGYGPIGQRVAKMCRALGMEVLVAARKNDTAPVENGNRVTPATTDASQPNGNGDAHRTPFAEVLRRATTLFLIVPLTAETKNLVGEAEMATMRPDVVIINVGRGGTVNEAALVAALREGRISGAATDVYEVEPAGSGRDSVLLGEGARDLNLTLTPHLAWCADQTRVNIRRVVGENVRLFFGGGKGSNVVLDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGI9</accession>
    <name>A0AAD8UGI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Serine endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_721190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362773.1">
        <property type="nucleotide sequence ID" value="XM_060512360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGI9"/>
    <dbReference type="GeneID" id="85396258"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1710">
        <property type="entry name" value="Subtilisin-like superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041947215" evidence="9">
        <location>
            <begin position="21"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="171"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="11">
        <location>
            <begin position="609"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1722718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="890" mass="94722" checksum="53BDD2425EDCB2E1" modified="2024-05-29" version="1">MKSFVKQAAFAACLPWLVVSGYDDAFVVEFDASVQLSPGDLISRTQASLAASGLDCTASSRYHFTHAVFQGGSFNVDCTNTGVSQKAVLSTIQSIDGIQKAWPVTSAAPAVHMPRIPGISDGDWGSRTHGSSKRDLSQILTLHARDGIAADTLPTHVDTGVSKLHASNITGKGIRVAVIDTGFDVDTPGLSKTDIVYAHDMTDGDNDVRDNCSFHGTHVLGIVGAKGDEGRFGVVGVAPDATYELYRITGCTSGTQDDAIINSFLEAAERGVDVISCSYGGDLTFPEDPWSIVATRLFNNGTYVSLVAGNGGPGIFTGASPGGADAVAAVGSTDNSQTPYYNWGGNWTAGGESGALRFVPGMPFDFPSNEGLTVWTSDTPNTNGCQLLPDKSTLPADLSKVIFLSQFDQCWMAADNSTVSLTKEFGIPYVMYYSSSNYTVSEGPLFLKVSAANQKGSVTVDYETAKQLLDAKAKYGSVQVFLANEVSVADVSLTYKANNRSGLMSSVFTSWGPTLRAGSMPAFHAPGGNILSTFPGWLGGYGVVSGTSQATPFVAGIAALVKQQHPDYSAEDIRNVIAATSRPVKWYDGRGNAGDFLAPVFQQGASALSFNDTANRPKELTFTIKNTGLETTTYDLSHVGASSGYVLEKADSYQLTEAVVYPVYAEVNINPTTLSVEPGKTAIVSVSVSKEPALLEASTRVSYFGGYINVEAKGVTDVNKLSLPYTGFGAPLTTLHSINRDKSYLSSYNVTEGKASHAEPGRIYTCTLNITADVPASFPGHEYPGIEVFLFLQSRNMSIHMVDAKTGKIVANSYQSTSEVPWNGSTWYWDGSDDNKAPVPAGTYTWRVKALKLLGDAAKEEDWETWEAGTWVLEYTADSIFSSSLTVPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGU5</accession>
    <name>A0AAD8UGU5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_654829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361409.1">
        <property type="nucleotide sequence ID" value="XM_060510756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGU5"/>
    <dbReference type="GeneID" id="85394655"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638:SF1">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="15887" checksum="EBBE45984A5C05E0" modified="2024-05-29" version="1">MSLHYLPPVKPSAIALGTIFNHTAELAVLTPIFGQTYQRAKAANTKEEFARSKEAQGAAVAWGTSLVGSALQSYGVGALINATGTLSYKGAAYLGSLIFFATSAPGYISQVFVEKRPVDTVGVSVLAKVIETVGLSVFLTWWGTRTNPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGV1</accession>
    <name>A0AAD8UGV1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Adenylate cyclase</fullName>
            <ecNumber evidence="5">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_579573</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364092.1">
        <property type="nucleotide sequence ID" value="XM_060505257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000408">
        <property type="entry name" value="Adenylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000055">
        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000220">
        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000305">
        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013716">
        <property type="entry name" value="Adenylate_cyclase_G-a-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08509">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00789">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="7" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="19">
        <location>
            <begin position="257"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="20">
        <location>
            <begin position="1052"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="18">
        <location>
            <begin position="1391"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="197"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="733"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="779"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="818"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1724037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1774" mass="198203" checksum="2549842E7E9E742F" modified="2024-05-29" version="1">MYGSNRSRAQSPTPSGGYFSSRHGTVDGSTSPSGQQQQQQQPQHHSKRNLLHRLRRNKDKDDGASRLRDLPGSTRSLATKPSRPEFARPELSPSTFPLAFSGTEPGSDQDPRLAAYNQRNQTFNNRFPFSKSKGRQQRTMEPDEQIGPTDRQPGANNNLGSLGGIHLDTNLSDMDGILTKPQPLTPMDSGVFSSIGDSEKVEQPPPVPAKPDAVLGPNGSWNAPDSWAVRRNTEDTTYQAPDIDDIGSPPRPDEKMTPYCIRIFRSDGTFATLSMALDASVTDVISQLIKKTYATDGLENYHIILKKHDLVRVLAAPERPLLMQKRLLQQIGYEERDRIEDVGREDNSYLCRFMFLSSRESDFHSVTNDLGLGRIQKFNHVDLAGRNLITIPISLYSKASEIISLNLSRNLSLDLPRDFIQSCQNLRDIKFNNNEARRLPPSLGKAAKLTYLDVSNNRLEQLDHAELNGLQGILKLNIANNRLKALPPYFGAYRALRNLNISSNFLDKFPLFLCQVETLVELDLSFNSISSLPDEIGRLRNLEKFVMTNNRLSNALPDTFSELQGLRELDIKYNAITSIDIISLLPKLEILSADHNSISQFIGSFDRIRSLKLNSNPITKFEINEPVLTLKMLNLSHCQLASIDETFNMMLNLERLVLDKNYFVSLPPLIGNLSKLEHFSIANNNVAELPPSIGCLTELRVLDVRRNNIRKLPMELWWANKLETLNASSNILENFPKPGSRQPRPSGEEAQTPAAVNKANPMERIAQSPLEESPDPSRRPSQNSSSTLLSVGPSPVPGGGDRKSSVVSVYGKGGRKTSVVSRSTSAGTVPPLPPSATARKDSSLSSRLYTTFAGSLRNLYLAENKLDDEVFDQITMLNELRVLNLSWNYINDMPQRSIKSWPQMVELYLSGNELTTLPADDLEDASLLQVLHINGNKFTNLPADISRAKKLAVLDCGSNSLKYNISNVPYDWNWNLNPNLRYLNLSGNKRLEIKQTTVGPAVTNRESLADFNRLSNLRVLGLMDVTLTQPTIPDQSEDRRVRTSGSLAGHLPYGMADTLGKNEHLSTIDLVVPRYNSTETETLLGLFDGQALSSGGSKIAKYLHENFGHIFGMELKGLKTRLNETPADALRRAFLSLNKDLVTIAIQHTEERSQKTHRGSATPVVLSKEDLNSGGVATVVYLQNTELYVANVGDAQAMLIQTDGSHKILTRKHDPAEPSERQRIREAGGWVSRNGRLNDLLEVSRAFGYVDLMPAVQAAPYVSNFTIREQDDIILIATREFWEYLDPALVVDFARQERGDLMRASQKLRDLAIAYGATNKIMVMMMSVADLKRRVERSRLHRGQSMSLYPSGVPEDLQQPMRRGKRNKADVLDSSLQRLEAEIPAPTGNVSIAFTDIKNSTTLWEMYPAAMRSAIKLHNEVMRRQLRRIGGYEVKTEGDAFMVSFPTATSALLWCFAVQMSLLDVNWPSEVINSVSCQALYDKDNALIFKGLSVRMGIHFGEAVSEMDPVTRRMDYFGPMVNKASRISSVADGGQITVSSDFISEIQRCLENYQDTDRNGSTGSEDTFDDDQMGSAIRKDLRSLSSQGFEVKEMGEKKLKGLENPEVVYSLYPHALAGRIEHHQQHEQRTEVDKPAILQAGSELAFDTESIWALWRVSLRLEMLCSSLENVSGQGLQPPETELLERMKHRGGEVTERFLLNFMEHQVSRIETCVTSLSLRHISFGSAPLQQLEDMRGPMSDILDQVAKQMAELARYKALYGELNDTEDDGSETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH67</accession>
    <name>A0AAD8UH67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_581716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363148.1">
        <property type="nucleotide sequence ID" value="XM_060505483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH67"/>
    <dbReference type="GeneID" id="85389382"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="49"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1723093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="146" mass="15480" checksum="EE81A8F7E00866AC" modified="2024-05-29" version="1">MDPSQSATSLPPEAIALAGRMYDAARKGDVAIFQQALPAGLPANMTNEKGDTLLMLAAYHGHADLVKLLIQHGADANRLNDRGQSPLAGAVFKQEDKVIEVLLEGGADPDFGAPSALQCVAMFKQEEKWQAKFESAPGRGKAVPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHV3</accession>
    <name>A0AAD8UHV3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000065">
        <property type="protein sequence ID" value="KAK1723453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363508.1">
        <property type="nucleotide sequence ID" value="XM_060510592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHV3"/>
    <dbReference type="GeneID" id="85394491"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="190" mass="21336" checksum="D77E180FB6274737" modified="2024-05-29" version="1">MGSHNVARVPAPAPRTTDLHSPITKRLTNWSRPSARSIGRRGQIHGSDARSRERVQACFPGRKVQASEFESSDPRWLSLGLSRTRTRTTVTTTSRILESTSTLTHHNSPAYHPKQKRTWKARAKASRSSVHSDHAHLPPLPSSGPRPDQLHRSTIQYPPKLASVTLHHAAQPSWSRQPWDLKSLVKVWPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI38</accession>
    <name>A0AAD8UI38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_584698</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361744.1">
        <property type="nucleotide sequence ID" value="XM_060505784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI38"/>
    <dbReference type="GeneID" id="85389683"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="159"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="749"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="798"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="693"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="750"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="798"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="837"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1720233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="861" mass="94393" checksum="50F0214B997EA94D" modified="2024-05-29" version="1">MFVERRLPTVHRLGEPVESSLNQTREHWSVEPRSAMAASSHNPYPRSPNPSTRSYDSSSVSSATSPRQPTQYIPRGLMNTGARTTAAPPPQPIGIPPLPPMNQNAFTPYTPVTAGSMMGRDSLPSADSVASTPGPSTASLPPISQAQKRAYRQRRKDPSCDACRERKVKCDATETTSCSECSSRNVKCQFTKETNRRMSSIKQVQDLEKQMERLRRDNTNLKRALQERDGAMDVDPDGLEPLPLQLPELNADIKRRKRPAPIHDLARARSNMRIFSRGIWKAPAQYRQAPSTPLFDPQRPELPPRQTTDQLLHTYYGSAHTMFPILHWPTFQMGVEDLYRIGNTKSVQPAWLSTFFSALALGSLFSQDPHRAFRAAELLEVARGMIDPWNNDYVLDNVRALLLVTLCLNEMNQKSAAWTWLGTAVRAGQDLGLYSESGPWPVIEGEMRRRVWWTIYILDRSLALDLGRPVLIDDTDCDVSLPAPVDDHYIHEGGIMVPPGREPLNHSLLAVINVVRSYSSLIKTLAAPIVVPTRLATFETHFNACHALFPQVCDTASTGQISPHLLTPYTYLLHARFALHRHNLAPTCPSDVRLAAMEQCTHIALETASLLSRATPTLADGATALLTTHTFRCALFLLLAGYWDHATTCLRALATIDSKRDVAIPCGRFLAFFVSTLGTKRTEYAAFVARTTPPKPFAPPPPPHGRPGPSPLQEALMQDEELLAYVSADLQAAPDSAWVWAGGEREAILSPTSPGSITASGGASSGLFSAEQRTGLSDEEVKEWGGWERLEAALRGLASGNTTPTPTSATWTSALPAGIKTEGTPTLPSIMPGPGEGSSNNSPTTSTKGRPQDRLSIANII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UID4</accession>
    <name>A0AAD8UID4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6 zinc finger domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_621458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364887.1">
        <property type="nucleotide sequence ID" value="XM_060508266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UID4"/>
    <dbReference type="GeneID" id="85392165"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="506"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="65296" checksum="5E1B57E4A3DEC935" modified="2024-05-29" version="1">MSNSRGLPDVLMTKVDEYVDSLAPQIQPRIASEIDTFQTRTIDSLEDQVVDAFRSLFNKDKNSDDGSRGLNDTPPDAYGIQSLPFADEIGKLTRSFSVITDEAGDDLRDIFNLTDEARGGGGGGPETQSRGISHSDSFGGAKGFLSSAINVVQDHLEKNKGSGGGGQGFELDGLLGVLSNTVKDAARNPEEKARVISPEIKEKVGMKLREQHAPIAEQFTKIALEHIKRWLRGNTSTRDLGDGVKGEIEDQVKDLVKGLGGLFGNKKSSQEGSRGIGDRDGPEGEGEKGGFSKVISDKLSTGLAKVHREVRLEFRKILGAIEKQLFELLPDAFQRPLEKILGGNPFDSQLDRDAGGHADRGFGDDIKVKLVNKIRALVRKVQETLRESILGVVNGGHRKFERESWVFVQNIVEQKVQKYLPKVKINVPDDIGNENVSVGAPTAGSQLGGEHHSGQPQGGNYAPPPSQQYGGQGSHPQQSYNPPPSQEYRPEQHQQQHQSHQEYRPDQNQPPSSYQQYHSDQYQGQGQNQNYGQSQNYNQNYNQNQDQGYGQGHGQGQQNYGGNQSYGGNQGHESGQGYGGNEGYQQNQGYGENPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIM0</accession>
    <name>A0AAD8UIM0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_654984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361280.1">
        <property type="nucleotide sequence ID" value="XM_060510771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIM0"/>
    <dbReference type="GeneID" id="85394670"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="264" mass="29418" checksum="D7C97BA38DAFBC5D" modified="2024-05-29" version="1">MSGNKSQGIEGNRGLVVALSTVLSVLGVIIIIGAIFLCYRYRRGRLPFSRRGNSPIDDEEIESWKACRTIEKCTTVVVDKHDSAGYIRKPASVIVYQNHSQHQPRPSTDTAPRSLYHKRSMDKKSIDIPQTPVLARAPNARVGLTDDAVEGDLAFLPSPKRQNSRLSKLPSPRHGRHRSSRSSASVGSLREHWYGYHTDTEMSPRPSVDPYSRMPSSAHSDVRHQRVYSSPSNPPRLSLDEEYHMGGLSPRPFLRQSEIGLAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIT9</accession>
    <name>A0AAD8UIT9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="6">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UTR4</name>
        <name evidence="7" type="ORF">BDZ83DRAFT_430523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000081">
        <property type="protein sequence ID" value="KAK1722318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIT9"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03117">
        <property type="entry name" value="Salvage_MtnC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027511">
        <property type="entry name" value="ENOPH1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371:SF1">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01133">
        <property type="entry name" value="C1.5.4:_Enolase-phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="128"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1722318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26562" checksum="DB15C0E739FB69BB" modified="2024-05-29" version="1">MAHNLGVISVVLLDIEGTVCPISFVKDVLYPYAVDALPATLDKQWDNPEFAVYRNAFPEDCVSDRSVFEAHFRDLVKRDVKASYLKALQGYLWKEGYKSGEIKAPLFPDVAERLLSWKDAGLRLVIYSSGSVPAQKLFFGYTDAQPADLTPLISGWFDTVNAGLKTEPGSYASILSSFADTKPEEWLFLSDNPNEVTAAIKAGMHSIPVVRPGNAPLPDDLSPTLQPIRDFNELKGLGSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ42</accession>
    <name>A0AAD8UJ42_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EthD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_583602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tpcK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362239.1">
        <property type="nucleotide sequence ID" value="XM_060505678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ42"/>
    <dbReference type="GeneID" id="85389577"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041922996" evidence="2">
        <location>
            <begin position="21"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="EthD" evidence="3">
        <location>
            <begin position="39"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1721443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="177" mass="19420" checksum="0445E57A5572028C" modified="2024-05-29" version="1">MVRLSVPLTIAATLIASGMAACSNTGQAQMVTYVKRATNLTQEQFWDYWQTQHAPKVAPLAVHFNITRYQQIQVGGQILPTEAGSTVPASTVPVDFDGIAMFLYKSPAVLTAMLSHPYYLAVVEPDEHVFIDKGAFGNGMVATFVGTDIEIVDGKQDVWVGSQATREKFQKIFESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJA0</accession>
    <name>A0AAD8UJA0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_323046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000047">
        <property type="protein sequence ID" value="KAK1724911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364966.1">
        <property type="nucleotide sequence ID" value="XM_060502384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJA0"/>
    <dbReference type="GeneID" id="85386283"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="216" mass="23684" checksum="5F964F34007034F5" modified="2024-05-29" version="1">MPAGRPLPGRLSESLTMVRGVYLFPTTPQALRSRHVSVDPSIHTPQNQRLCRRVSEDRQAIRCKPSDPVSSQARDGEVQRIGYRPQEGHYRKRNKALQQDAYAGHRLQWCATFSHWTSLRLSAKVQGQQSAKIAREPPDGKEKRGLGPLGSVQDLPASPPEASASKVTPLSGTPSPPNAKTCAQHCGTLPTSPRIPRILPQTPYGYVQPDSQCLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJA6</accession>
    <name>A0AAD8UJA6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_416665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362628.1">
        <property type="nucleotide sequence ID" value="XM_060502957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJA6"/>
    <dbReference type="GeneID" id="85386856"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041622">
        <property type="entry name" value="SLATT_fungi"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033635">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793">
        <property type="entry name" value="SLATT_FUNGAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38793:SF3">
        <property type="entry name" value="SMODS AND SLOG-ASSOCIATING 2TM EFFECTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18142">
        <property type="entry name" value="SLATT_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="SMODS and SLOG-associating 2TM effector" evidence="3">
        <location>
            <begin position="80"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1722573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="228" mass="24751" checksum="32076B755D94ECC9" modified="2024-05-29" version="1">MSKPLPSRPSDDHNDENSPLLPRDASPSSPHNEADADPNPSTLLLFRRAVGINTHLQPADDCDLEAGRTSALGIYASTIAAHRRFRTLRILATVLIYSCHATQIVVGGVLTCLGPKAGVHRTSITVLGGVNTVVAGVLTWMKGQGMPDKLKGKEIEFRRLQNWIEETEALMVLGTVGGTREEVGGLVEAAYRRWNAANERGEDGGPGEEYEDEGRKGKGSTMRWLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJJ4</accession>
    <name>A0AAD8UJJ4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_753073</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000058">
        <property type="protein sequence ID" value="KAK1723952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364007.1">
        <property type="nucleotide sequence ID" value="XM_060514297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJJ4"/>
    <dbReference type="GeneID" id="85398195"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF29">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1723952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="566" mass="61899" checksum="85AAC06ACB4E2935" modified="2024-05-29" version="1">MGLGILESKALDNVPGTTRYFDDPNRPQTANDSHHGLKVDASGDVPIILVPQPSDDPNDPLNWPLWKRDLITFVLSMTAIFATALGPILAANTVTIALLFRTSFTRIALLTGYFLLGVGAAAIFFVPSARVWGKRHLFILGICILVASSAWAGSVGTSYNSLLGARIVQGIGCTPFETLVNAAVGDLYFVHQRGSRMAFTNLAVFGGAFFTPIVVGKITHSIGWWWTFYLEAIFCAVCLPAVFFLCPETAYRRDTALNTDMVADSIELTDNKTSYADGPGSRSSDHEKLNPTSAPYGSGLEAVRGAGAQTPKKTFIQSLALFDGRKTDEHYWKLLLRPFPLFAQPAFLWGCLIQGTMIGWTVFIGVIVAALFLGPPYYWNEVYAGYAYVGAFVGALVGFIIAGAFSDWSAKFLTRRNNGIYEPEFRIVMVLPMFIIGSIGLYGFGVTSAGLSAREYHYSIPLVFFGFEVAGMVIGAVASSLYIVDAYRDLAIEGFTIMIIFKNIFSFGLTFSAYDWIIGGGIKPTMMAIASIQVVVCATSIPMYFYGKRIRAYFHQHDLLKLTGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJL2</accession>
    <name>A0AAD8UJL2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">O-acetylhomoserine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="12">2.5.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_578617</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-acetyl-L-homoserine + hydrogen sulfide = L-homocysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:27822"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.5.1.49"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-acetyl-L-homoserine + methanethiol = L-methionine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10048"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16007"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="EC" id="2.5.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-acetyl-L-homoserine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="12"/>
    <dbReference type="EMBL" id="JAHMHS010000051">
        <property type="protein sequence ID" value="KAK1724458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364513.1">
        <property type="nucleotide sequence ID" value="XM_060505147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJL2"/>
    <dbReference type="GeneID" id="85389046"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071269">
        <property type="term" value="P:L-homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000083">
        <property type="entry name" value="O-acetylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000035">
        <property type="entry name" value="O-succinylhomoserine sulfhydrylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797">
        <property type="entry name" value="HOMOCYSTEINE/CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43797:SF2">
        <property type="entry name" value="HOMOCYSTEINE_CYSTEINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 13 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1724458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="452" mass="48647" checksum="BEF87D57B2F7EEC1" modified="2024-05-29" version="1">MAEELSKNFETLQLHAGQEPDPTTNSRAVPIYATTSFTFNDSAHGARLFGLKEFGNIYSRIMNPTVDVFEKRIAALEGGVAALATSSGQAAQFIAINALAHAGDNIVSTSLLYGGTYNQFKVFLPRLGIHTKFVDGDRVEDIAAAIDDKTKAVYVESIGNPKYNVPDLEAIAKVAHEKGVPVIVDNTFGAGGYFIRPIDHGADIVVHSATKWIGGHGTTIGGVIVDSGKFKWDNGRFPQMTEPSDGYHGLKFWETFGPITFIIRARVEILRDLGASLNPFAAQQLIIGIETLSLRAERHAQNALALAKWLEASDYVSWVSYPGLESHPYHETAKKYLKRGFGGVLSFGVKGGGDAGSQVVDGFKLISNLANVGDSKTLAIHPWTTTHEQLSDEEKTSSGVSEDLIRISVGTEHIDDIIADFEQSFKNASSASTTGKPAPAAETKQDDAPLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJM9</accession>
    <name>A0AAD8UJM9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_620525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365176.1">
        <property type="nucleotide sequence ID" value="XM_060508195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJM9"/>
    <dbReference type="GeneID" id="85392094"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="32"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="509" mass="54872" checksum="86BA9860539CA51F" modified="2024-05-29" version="1">MKSISTTSVTNVPEEEKDLPLGQAIRQYPKVVAYCLSLTIVVIGWGYALVIVGSIVAVEPFQHDYGELYKDKWIIPSLWVSLWSAAIPLGMAIGSVFAGWYQDRVGRIWSLRTGAIICAIGVAGIFFSYLPANIETMRALFFAGKTVQGIAIGILKVTAMTFISETAPTSLRASVMGLVPTGNLLGQLLGSIVVFLVNKAPNRTGYLVAFGSQWLLAVVPFILSVIIPESPAYLEERGQSDRALESSRKLYAPKVDAAKVLEKVRASIAQEKEATSGATYLTCFQGVNTRRTMIVIMANLLPAMFGLDLIAKSSYFLQTIGMKSSTSLMILIGGIVAGTFANGVGLWVLSRVGRRKVTLISMSISTILWIAVGISGIWRGPAVAYFTAGGCIAIIIVCGMGAWPAGYAIMGETSSLRLRAKTQGIGGVAQQGSSVLINFLLPLAYNPDAGNWGGKTGFIYVGLCALGVLLSWLFLPEMKGRSVMEIDHMFNIKLPARQFKKWRGDVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJN2</accession>
    <name>A0AAD8UJN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BRO1-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_631203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palA/RIM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361760.1">
        <property type="nucleotide sequence ID" value="XM_060508892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJN2"/>
    <dbReference type="GeneID" id="85392791"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09241">
        <property type="entry name" value="BRO1_ScRim20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09236">
        <property type="entry name" value="V_AnPalA_UmRIM20_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="4">
        <location>
            <begin position="6"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="734"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="641"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="741"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="844"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="856"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1720249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="866" mass="97044" checksum="2733070D9F5D4EA4" modified="2024-05-29" version="1">MASISNILSLPFRKSTQLSLSSTIRQYINTKYDQHPDMFRQDLEVIDALRRDAVNVREPHPSGVKKLQAYAGQLVWIGGKFPIDIGAEFTWYPALGYNTERPMVRNNLKYELMNILYNLASLYSQLAVAQSRSGTEGLKTAAGHFASASGVLEHMLKEVLPELRMSDPPEDMDANTLESLSQLLLAQSQECFWQKAVMDGYKDAIIARLAARVSDLYNSAGEAAMKSEAISSAWIHHMSAKHHHFAGAAQYRAACDCLEKRKYGEEVARLQDAVSCVNEGLKESRGGYLNKAVLEDLNGLKRKVEEDLKRAEKDNDVIYLQPVPPKSELKILDRANMAVARVPPQVANPFDYVGDQAEFGPALFTKLVPFSVHAAITIYEQLRDRIVNENIIGQMETQTEKLHAMLSSINLPGSLQALEKPLGLPHSLVHHAEEIRQADAIGRIQRAFSDIDKLRTADIAIFNEGKAILAAEEEEDNRMRRKYGTDRWSRPESRSDPQGGQFWAQVAEIEGYFASSTSSDAVVREKYKEVQDLLEMLSGSDRAIMDYVPSSRRMDIPEHLKPVIGRLRGAYNDVLRLESKRRKKAEALREKARTDDIKPDILKEAARLERTYPTTAIVPAHFEDFFEKRLDKLYDSEIEAVAKEEDEQERLMTEVQRVNREFESQKKNMSSGSRERELALQKLDNAYYKYKEIVNNVDVGRKFYNDLSKVVGQNFRDPVKAWAAERRMDAKSLEEEVSMPPLNSLNLNRSPVHSPTGSNYDPRSQSYFSASVVPGTTAQQQQPPSRHEVHSPAEAHIQSWAGSTVEPQHPRPAAAMSNMWQPDMGIKFGAQPGAPAPPGGPTQGQGPASQPPQGGTWNPSSGIKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK03</accession>
    <name>A0AAD8UK03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_584228</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361940.1">
        <property type="nucleotide sequence ID" value="XM_060505738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK03"/>
    <dbReference type="GeneID" id="85389637"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="699"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1720429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="767" mass="86478" checksum="95DC0B55B7472BCB" modified="2024-05-29" version="1">MSTRSPEELLRAVEASHDQYLCNLRSLHDSLASAVRDRSDTKTTNNTRQPSPLLQPSPSPVHSPGQSPPLSSEATFQPALRRARRSTFSDPIEKRTLPSVVERKHVSASIHSELDVEYLPLLDIAGPRSVNSSDGTLAIPPTKLVERVSWTDNQLLRHLKYTDFTGGAAIALTDVIRRQADIDEDAVFEEFAAYESQGYVSSTFELYDVDKEGSPRPVGKHPDRRPRNAAADAAPTPTQIVDAPTVWNALKEIHADGQAVGLVTILQEPSALMLGALHMTMRPYFDMTELLNHLITDHENNGKTTAHVHRAFAKDASPSHLRQRSFFFVFKYYTVVGEGLEPAPFQKYDKRPADRRSKDHIDIAECSSILALSLSGPPRQSVKQTRRREGPQEGFLFDTFAPWHLLSIQSFPDDEHTLRGGDAEAHKNFPSGPYAFLDALVTEYRDATKRNLALHARIAKLITPPTDFMFDARLRDKLLFEDKHFTYIRRYFWAYNTLGVVNEGLRAMLAAYRETFPDDFWEGRHQTLWPHPAPESPEGAAYRDKMVLLRSDLERACRDLETVHAKNAATRKEIENLRDQLFSGSSIKESRRAIEQGDNIKVLTLGSMVFLPLTFVTSVFGITEFTISPEDWRFPVTMVCVCVPFIVALILLQTRAGYSLARHTFAALAWPFRLFTDAGTDEQFTPAAVIIPVTETRPRRKRRLTGRRPSPTRSLRHQQQQPPPQQHQRNNDLGLIQSFMGWWTWVRKNGVRGSGGEQGDGSAFANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKI5</accession>
    <name>A0AAD8UKI5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_580735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000064">
        <property type="protein sequence ID" value="KAK1723530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363585.1">
        <property type="nucleotide sequence ID" value="XM_060505376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKI5"/>
    <dbReference type="GeneID" id="85389275"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF33">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="71"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="576" mass="61444" checksum="5694F69893F444C4" modified="2024-05-29" version="1">MARVKISQSGEGVQRVVDESSPLLSNTRRGSSSSEVVDSSVDVEQVTPVATASDDPKLQAQKTSTWAVVKIVSILLVGTFTANADGSLVMATHPTIASEFDDLENSSWLFVSFALAGAATQTLYGKLSDIYGRRALLMVAYTLFSIGCAMVGVGRTMWQVVLGRVISGSGGSALNVLGLLLVTDLVPLRDVAAWQAGINLAATVGRSLGGPVGGWLADTIGWRWSFLGQAPIFLLAVLLCWFFLPKGKQVGKGEEGAEARGKPIDIEKSSLARIDFLGAALLALFILTFLLPIEIGGTKIPWSHPLIFILFGVAAVFGGLFAAVEEWWAKEPIFPLELLKHRDIILTYVISGGQVAAQLGLMFSVPLYFQVTQRVSNTVAGIHLFPAVFGNAVGGVLAGYLIRKTGRYKSLLIIATVASMFSYSLLLLRWHGDTNAWESLYIVPGGFGAGLVQSAGFISIQAAANPKHKAAVTSGMFLTFQIGMILGLSCVSAVMMETMRWRLDALLEGMDLSAVVRKQIIAKATSSVDYIDHADKKVSAAVVQAYVEGLGFSHGFSLISSALALIAAVFVREHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UM88</accession>
    <name>A0AAD8UM88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_574528</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366466.1">
        <property type="nucleotide sequence ID" value="XM_060504719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UM88"/>
    <dbReference type="GeneID" id="85388618"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF81">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="515" mass="56762" checksum="E1CBCB143818AF6C" modified="2024-05-29" version="1">MAEKVSKDIKVAEDGLEPTKSFTAGEVAHLDESEAFLQENNITEEYLAELVNDKEKNRRLVRKIDLMILPLLAGTYVLQYIDKQALSYAAVFDLFSSTSVTQTEYSWFASIFYLAYLVAEYPWVYIAQKTRMGKVVAGCVLSWGSVLMITAACSNFPGLAACRFLLGVFEAPITTCFMMMVSMWYVRSEQPMRAGLFYCCNGVGSMLGGVLSYGIGQIDSFPVWKAVFLICGGITVVWGGLLLVFLPDSILSAKRFSLEERALLVGRARLAKTGVLNKTIKWYQVKEACLDPQVWLLTLFVLLNEVINGGVANFGKLIIKGLVSDPLLTTALGIPQGAFQVFWILTGAYTASRFRNQRTTVMAVWLIPTIIGCCMIWKLDRTHYKVGVLFGYYMIGCYVASLVLALQMPATNLGGYTKRITASAIVFTAYCVGNIIGPHAFLAKEAPLYETGCKLILACSASQVAIATGLRMLLIRRNKQRDAAAAAAGISPDAEHEDEGVDLTDKENPNFRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UND2</accession>
    <name>A0AAD8UND2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SNF2 family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_574238</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366598.1">
        <property type="nucleotide sequence ID" value="XM_060504694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UND2"/>
    <dbReference type="GeneID" id="85388593"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="454"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="795"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="876"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="128"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="284"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="386"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1726543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1044" mass="115648" checksum="5DD5DC29D1E00F0E" modified="2024-05-29" version="1">MTGRRGRPSLAQKESMASTRGNSPDPLSVAGTGRLTRSASSRNLAAAAQPVTSAPPTAKRGRGRPSRASLANDSASSTASASAAASADLTSASEASTPATSNVATPAPSVSGSGYVPLVLPAALRNPRLKGPQSASKFEVQLPTSAGLNERALRHSQYSMQPAKRKVGGGYYDDDDEEDEEPSDNDRDAVVARRLQKEENKKSTASTGLSDAALARRLQEEEYEMDESDVPLATGRGRRATAAKATVKDSDADSEDVPLLSRSKPVGRGRGRPPKKQKVVVPESDNEDEPADSTDDELSDLSDNFSELEDDDSNKIPKKAKAKGKAKQPVRRTRASASTLPPASVGLPEDEDDALSSLDSGDFDSSESDEADSDGGLQSAVAAQSRGRRAYQRGSKRRGMLERARLENNHPELLTMWQTLEASPALRPDKIAQPQQISRQLKPFQLEGVSWMIEMEKTDYKGGLLGDEMGLGKTIQAVSLIMSDYPQKKPSLVLVPPVALMQWKSEIESYTDGTLKVFVYHGTMKNAKNMTLKELKKYNVIMMSYNSLESMYRKQEKGFTRADGVHKEKSLIHQVDFHRIILDEAHSIKTRTTMTAKACFALKTSYRWCLTGTPLQNRIGEFFSLIRFLQVAPFASYLCKQCPCAGLDWNLDDDHRCHSCGHAGMQHVSVFNQELLNPIQKFGNFGPGREAFQKLRLMTDRIMLRRLKKDHTNSMELPVKEIYVDRQFFGEAENDFANSIMTNGQRKFETYVAQGVLLNNYANIFGLIMQMRQVADHPDLILRKHGEGGQNTLMCGVCDEPAEDAIRSRCKHDFCRACARSYLLSSAEPDCPRCHIALAIDLEQPEIEQNEADVKKSSIINRIKMEEWTSSSKIELLVHELHKLRSDNASHKSIIFSQFSSMLQLIEWRLRRAGITTVMLDGSMSPAQRQASIDHFMTKTECECFLVSLKAGGVALNLTEASRVFIVDPWWNPAAEWQSADRCHRIGQTRPCTITRLCIEDSVESRMVLIQEKKTNMINSTVNADDKAMESLSPEDMQFLFRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNS0</accession>
    <name>A0AAD8UNS0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_619680</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365535.1">
        <property type="nucleotide sequence ID" value="XM_060508142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNS0"/>
    <dbReference type="GeneID" id="85392041"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000019">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000006">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000771">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="13">
        <location>
            <begin position="1058"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="794"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1725480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1220" mass="136340" checksum="C3D9432ACD8F4489" modified="2024-05-29" version="1">MGERSSSAARTPAKTPTLKRQPSSSAGTQKTIVQFFSKSTSVSRSTPTPKPTAKAPDSSPCLRESKRTNTLPQAPKSSSLTPVPSSDAIEPASSQENLSVSTVKVADDSLPSPSTSAEHMTPQTTTKLPVPSSSPTRKSRKPVNYAEASDDEDDDPFIRLRTASTRRRTRTPAAIVDDGDDYEEDTASNDLPEDDDDMIDFVVSDESDEGSQSKKRKRPATSKAASRKKSHVSSPIKEEEYEEIDEEAMLDVPVPSTAQQWRYDPNNVASAATRTAPTQQARRTLKTKEKAHTREPEDRYPWLANIVDINKKPRGDPDYDPSSVYIPPGAWNNFSPFEKQYWEIKQKLWDTVVFFKKGKFYELYENDATIGHQLFDLKLTDRVNMRMVGVPESSLDMWVNQFVAKGYKVARVDQMESALGKEMRERGDTSAKSKKADKIIRRELACILTGGTLVDGSMLQDDLATYCASIKESTVDGNPAFGITFVDCATGQFSVTEFEDDSDLTKFETFVAQTSPRELILEKSRISTKALRILKNNTSPMTIWNYLKSGSEFWDAETTRRELENSNYFAKEDDGEGAWPDTLAKAKGKDLLMSALGALVQYLRVLKLESDLLSQGSFDWYTPIRRNGTLILDGQTLINLEIFSNTVNGGQDGTLFTLLNRCVTPFGKRLFRQWVCHPLCDIKRINERLDAVDMLNSDRGMREKFTSQMTRMPDLERLISRIHAASCKPEDFVRVLEGFEQIEYTMELLGEVGGGNGLVERLVASMPNLGEPLAYWKTAFDRKKAKEDKLLIPERGIEEDFDNSQDRIEAIKEELQTLLTAKKSELKCKTLKFTDIGKEVYQIEAPKAVKVPRDWRQMSATASVKRYYFDELTDLVRELQEAEETHSQIVKEVAARFFHRFDADYETWSQSIRIISQLDCLISLAKASSSLGEPSCRPEFVDLERSVVEFSELRHPCMLNAVADFIPNDIELGGDSPNINLLTGANAAGKSTVLRMSCIAVIMAQIGCHVPATSARLTPVDRIMSRLGANDNIFASQSTFFVELSETKKILAEATPRSLVILDELGRGTSSYDGVAVAQAVLHHIATHVGCVGFFATHYHSLATEFENHTEIRPRRMQIHVDEEERRVTFLYKLEDGIAEGSFGMHCAAMCGISSRVIERAEVAAKEWEHTSRLKESLEKAKSGCYIPLGVLSDVSSLLKGGDELEKRGVEVLLKTIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UNY7</accession>
    <name>A0AAD8UNY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000061">
        <property type="protein sequence ID" value="KAK1723760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363815.1">
        <property type="nucleotide sequence ID" value="XM_060510560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UNY7"/>
    <dbReference type="GeneID" id="85394459"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1723760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="156" mass="17309" checksum="FD63C8A222661D7A" modified="2024-05-29" version="1">MFTLRIPAPAQSRLLLRTPCRAAALPFPAMARRLWALEVEPEVRLFSCRAHPSTLSTILTDAISMSQRNHLFALLWSPSSNARPPLPSPGLVTTSDPHPSKPFGGHRRLNPRIRPWLRSPRARCLLLDSRRGPLVLPEAQSRNPGSYACSPAISHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPY6</accession>
    <name>A0AAD8UPY6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIP41-like family-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_750134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367408.1">
        <property type="nucleotide sequence ID" value="XM_060513883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPY6"/>
    <dbReference type="GeneID" id="85397781"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1727353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="298" mass="33533" checksum="86D0221F812AD12B" modified="2024-05-29" version="1">MNHITNPNEPFPTPSALAAATTTHTQRNFRVASRKLPISKAGPIDDMTASLGIPVPEMIFGDNLVSVSHVPTGWSIAFNAYDALDAVDKTDKKMLQVAYARDWSSSREKTSAGIKEVVKPYDWSYSTEYRGTLEEPSAGSATGAGAGVQQEDAQGNKNKLEETTTRMIPLELLKRRDPILFFDDVVLFESELDDNGISIVSVKVRVHEKRMLLLCRLFMRLDNVLVRIRDTRVYVDFETDEVIREYTAKEDSFDSVKRSLFMEGRLPDDIVIALRDPNLLYNLLPTVEQTVQSVFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQC1</accession>
    <name>A0AAD8UQC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_789605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368727.1">
        <property type="nucleotide sequence ID" value="XM_060515697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQC1"/>
    <dbReference type="GeneID" id="85399595"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="204" mass="19293" checksum="7ADAE52574D906A4" modified="2024-05-29" version="1">MPGVPIDALDNLKSKFKAIFKKKDEKKAEAKPAEAKPAATTTTPAATEPTKTEAAPAAAPATEPAAAPAPAPAAAAEPAKAPEPEAKKEDAAPATTEPAKAPEAAPAAPAVPAVAAEAPKAPEPATAPAPAAAPAAPAAPAATEPAKTEETPAPTAPAAAPAAAETAPAAAETAPAPAAAAAPAAAAPTEAAKPEEKKEAAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQF8</accession>
    <name>A0AAD8UQF8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_276391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366074.1">
        <property type="nucleotide sequence ID" value="XM_060502099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQF8"/>
    <dbReference type="GeneID" id="85385998"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041955484" evidence="2">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="157" mass="17353" checksum="A868E0BEE507FB93" modified="2024-05-29" version="1">MLLSSFPLTVDLTLLFLPPLHSSFPRGPWRHGPWQLPYLRQLQPFEIVASLLDSNDHKKAEPQAQPGKTRILDGNHPPGPLHYSLTAPPSKVPSNTLASTSHNTTSPHKPKATTIHLNLVYATLHYLHQTTPCLCDHGYQSCQIADPSVPREPPGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UR61</accession>
    <name>A0AAD8UR61_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_577528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000046">
        <property type="protein sequence ID" value="KAK1724915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364970.1">
        <property type="nucleotide sequence ID" value="XM_060505025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UR61"/>
    <dbReference type="GeneID" id="85388924"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042201134" description="Cell wall protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="18111" checksum="93F35716DF82D849" modified="2024-05-29" version="1">MLGFQVLLVALQAWAITAAPLLVARQKDTITTALGMVQTSLEKLDTAVKGISANDANSVAPVLTAAQGSQDALTKATSMIDGADSIGLFGALGLQQTADGLVTQVQTTLGDLSQKKPVFDQLGVTSVVKDALMQQKSGSGALGDTLLSKVPAIARPIAQMSTGQLTEALDGAIATFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URJ7</accession>
    <name>A0AAD8URJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_615838</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000032">
        <property type="protein sequence ID" value="KAK1726413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366468.1">
        <property type="nucleotide sequence ID" value="XM_060507923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URJ7"/>
    <dbReference type="GeneID" id="85391822"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000001">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF34">
        <property type="entry name" value="NAD-DEPENDENT MALIC ENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="120"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="311"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1726413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="625" mass="69045" checksum="CD666A51D18F4868" modified="2024-05-29" version="1">MPPRIIVNPLRNTITNRLSHLPRLSHTMAGTKDRKESKFSHLPLSTSGPISCAVTGSALLNTPYLNKGTAFPDDERREFNLTGLLPQSIHSLDQQLHRAYEQYKSRQDDLAKNTFLTSLKEQNEVLYYRLLQEHLPEMFSIVYTPTEGDAIQNFSRLFRRPDGCFLNINDIDRVYHDLAQWGRPEDIDYIVVTDGEEILGIGDQGVGGVLISVAKLVLTTLCAGVHPNRTLPVVLDCGTDNEELLNDDLYLGLRQKRVRGHKYDRFVDEFVKAARRLYPRAYIHFEDFGLTNARRILDQYRPHIPCFNDDVQGTGCVTLAAITAALHVSKQKLTDLRLAIFGAGSAGVGIADQVRDAIAAEGNMSKEDASKQIWLIDKPGLLTTDSEVSAAQKGFAKDPSDWKDKDASLLSVIKNVKPNVLIGTSTKPKAFTEEIVRAMADGVERPIILPLSNPTRLHEAVPEDIYKWTDGKALPVKGPWGEGGKEIEIEVAECNNSVVFPGIGLGSVLCRASLVTDKMLVAAVEGVASLSPALKDQTAPLLPGVDVVRDVSVRVARAVIKAAVKEGVATEEGIPEGDEDLDEWIREQMWSPEYRPLKLVEYSEASREAKGEMKVAGSFSRVGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8URN0</accession>
    <name>A0AAD8URN0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_717123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368278.1">
        <property type="nucleotide sequence ID" value="XM_060511913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8URN0"/>
    <dbReference type="GeneID" id="85395811"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF2">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="47826" checksum="79A43164B3E1AAEA" modified="2024-05-29" version="1">MWQMMPGLMASLRTHVANHRQHLSKSHLKDIIVQLSLAIVEVGIVTLAIPLFIVLPGILFGAWLGISMSMVLGLSWLMNGNEVMSSCDEFGSSTTDIDDDEERWIFIGGMGTSSTHLKHCTIPRLARLFGRSFSGIQMATYGLPFDMLLLAIQRCFPFETQASRALYTELRTALLDAAVHRVAVLAHNNGSLPVAHVLARLCSDIQAEKLSKLEIYTFGAAASEFVAPLGETSRKVTRFEDGSTAVVEERGPHIEHFAYANDPFAQMGVLRSVQKKLDGRFCGGVFVIQNQVPQPSGHWVPDQRPVMLLTDYLSALFPDPSSPQAPSSILDYVMMIDRDIAEKRELAAMANYAQTRRSRKDSRRLSWTGLGATVGGRSGVMDGVTGLEMARRGCRDCDGHRGREVSWLSNYVQTGWIVEKEAHVVDAMGIGGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US89</accession>
    <name>A0AAD8US89_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RED-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_266854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366259.1">
        <property type="nucleotide sequence ID" value="XM_060502029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US89"/>
    <dbReference type="GeneID" id="85385928"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="278"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="528" mass="58378" checksum="803119039D6008A2" modified="2024-05-29" version="1">MNNQQFRKLLGADSVKAASPSNASTKGAATPGGGALGSRQRSSIPMTPRSVGVGHSRNEFARQLAERNQAGQPQKKFRTSAPKGSRLAEGYVDRARDRTDDEEDDRAKRIKALEEALKNEEIDQATFEKLSSQIAGGDLSSTHLIKGLDFKLLERIRKGEDVYGDKKDNEEEAEAPPEEEVDDAFDELESTEVQAVEKEKVKKKGQLAPVALAPGKKRTRDQILAEMKAAREAAKAQQEAALNSKFKKIGAKQQAGSRIERDSKGREVLIIIDEDGHEKRKVRKLQPGAEEEMRKEFIPDKDAKPLGMEVPEFYQKQQEEVEEDDNDDIFADAGDDYDPLAGMDDSSDEDSEGEVKDNEKETKNESSADKIAMPPPPRPAQARNYFKDSKTDLISSQTLQGPSMSDPAIQAAFKRAAQLKAANKDPEGEAEDDDEEAKARRERHKRMLQSVDRDAEDMDMGFGTSRFEDEADFDDAPVKLSGWGNDGDDDDGQSGKSKRKRGPKKRKGDANNAADVLRVMEQRKAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8USP4</accession>
    <name>A0AAD8USP4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_718366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000031">
        <property type="protein sequence ID" value="KAK1726596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366651.1">
        <property type="nucleotide sequence ID" value="XM_060512063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8USP4"/>
    <dbReference type="GeneID" id="85395961"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042136815" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="32568" checksum="5F4B4F8A3C77B76B" modified="2024-05-29" version="1">MPLFNYLVQASIAVLLVIFGIQMQTTAAQAPPLTCMNVDQPNPIFSQYPNNATGLLNVTMVIIPIPMTTARQIIPQQYGILEGAYRALMPNFPADMYPVVVQAGHDHDIRFQDFGIPDFSKSGFEFPFLDLLGDGKSSFRWAPEQLISASNPAAVTGSQAYGTEVHAATFTPECNAYSATTGGGTSFNGTAGAKYMSLEMKKSACGGKAPPYTLAMFDTIINQPIFANGSTCDQQIRLFNTSVTTGAFEPVPVRGSLKSNLGPFQTDASFSDVAGFQAATPFIENNYLPCEMFRGYNPVKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTK5</accession>
    <name>A0AAD8UTK5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_113534</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368642.1">
        <property type="nucleotide sequence ID" value="XM_060501109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTK5"/>
    <dbReference type="GeneID" id="85385008"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000064">
        <property type="entry name" value="MFS allantoate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF97">
        <property type="entry name" value="ALLANTOATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="50"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1728587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="497" mass="54813" checksum="B05B336A7E0D80E1" modified="2024-05-29" version="1">MEPKSAIVDHDATEQTDVKDVQDGTSQYDETLAPTPAQNRRILWKTDLVVLPCAVISMTLAFLDKNALGFAAIFGLRQDANLKGQEYSWLGSVFYFGYLAMEFPALYLITKLPIGKFIGACLVLWGACICLMSACHNFAGLAAIRVLLGIFEAALLPCMLVLNATWYRREEQPLRTALWHNTFAGVFGGILSYAIGNIKGSLSTWKYIFIIYGAVTVLVGFVVLFALPDSPQKAWFFDEREKRQVVSRLAENQTGVDVKKKFDAQQILEAVKDPKCWCVWACAIGYAVANAGITNFNPLIISGYGFSQTKTVLMATPQAAVAMVAGVVLTTISMFVQNLRCLFWIFSALVGLVGAVMVHTLDINQNRNASLACVYIMGFYNVPWVFMLSLNSSNTAGATKKSFMGVTVAVCYAVGNIVGPQLFLSSQAPRYPLGISAMMFAFALMAASGLVYYLLCVAENRRRNSKFGVPEDRLQAGLEQEREDKTDGENKDFRYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTQ7</accession>
    <name>A0AAD8UTQ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_196689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367653.1">
        <property type="nucleotide sequence ID" value="XM_060501631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTQ7"/>
    <dbReference type="GeneID" id="85385530"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="229" mass="25318" checksum="BE20D3185BFE9E7A" modified="2024-05-29" version="1">MSATSQFPLATAASASLCNAICVHALTTDSGPYHGKAVPAPLRSSKISPTLKPCLVGLLWHRPLSPFPRNGCSISLLAPLSHLSHRPETIKNSAENSDRDKPWGAWHTEVNLHEPVTTDENPQPYRDPRVQGSMPRHWRGSASVSNSTMVRFFGLLTPQPQHPLASCLSVFWKPWPPTLTRGRRRSPKIYVHRKNRTILFMVAATPRVASGDHHKGYPAHQPSSLARNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUI6</accession>
    <name>A0AAD8UUI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_569774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368850.1">
        <property type="nucleotide sequence ID" value="XM_060504227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUI6"/>
    <dbReference type="GeneID" id="85388126"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046536">
        <property type="entry name" value="DUF6601"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34414:SF1">
        <property type="entry name" value="SUBTILISIN-LIKE SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20246">
        <property type="entry name" value="DUF6601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="40180" checksum="306B8AC3711C4D50" modified="2024-05-29" version="1">MDKSSVPFTVRVLDDAVNPAVTVQELRDWSDLLPATSRTKHDHITVPQADDIEFLERELLVQRINDVQDLLWICGRPMPPRSLHYQTISREIHITENPELHLVWAKNRIFVKPIPRWLLSSDFWAANLVEASGNQSDPRKQQLVACALGFLFTYTALIAYESDFRIAVERGLLPDRMNWYQWKAISAQIAQNHCYASVNPRYWYGELRLSRLNKIYRIRLGYLLRGYSKVVSHAVYEDLIRDNFATLAAMLGYVVIVLTAMQVGLATDRLVGDSAFQSVSYGFTVFSILAPLIAGVCIIGIVVVMFVSSWGVTKVYEKKRFQEMGVEPFWRFQKADNQYTKVESKQGPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X864</accession>
    <name>A0AAD8X864_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_685877</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000245">
        <property type="protein sequence ID" value="KAK1705309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357577.1">
        <property type="nucleotide sequence ID" value="XM_060511257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X864"/>
    <dbReference type="GeneID" id="85395156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF1">
        <property type="entry name" value="PYRIMIDINE PATHWAY REGULATORY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="84"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1705309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="819" mass="91198" checksum="332B0D39294B6E6F" modified="2024-05-29" version="1">MATRANPPKKVRLACRRCRTRRIKCDGEVPACTNCAKAGETCLDVDSQNSRLLVPRNFASAARARIQWLEDIIKQRLPDVDIAGGPQIDAFPDPKGSVVVGGGDHDEDNISTSSPRSGRGCSQPVPVGGTPSLGSQRPGSLKRTAEAAGSNDHDEEFPDRAHSVARNLGMLSLNSDSDQKHYLGSSSGVLFTNLIGASPSSAGSTPVALIDDVQAQGPASEWHDSTVSSNVSQEYNRALHVCLRQELPRKEDAIKLVHTYIRWMHPDYPVLEATSLLSSLDALYATFECSLEEDPLPNGWPSSVQAFRWNGRQITPSDQGVQAVPMPVVAFTLFMVFNIAAIMKIRSRIYEFPPERFYRAALHFSKDCFSQISLSSIQALVTLIIHSMLTPAEVNLFTLIHIALAHCVELGIHREPPAAIQPSSEFENQQIKRLTFFTIYSLDRQVSIGRPLGFRDETFDIMMPEPQSSRTGNTNSLNPIPSSFLEAVLKYARHQFELDRLVSDVKQQLYHLPCDSSWFSMPQSPTDQQGRIKQELVNWWRKVSEESFDFPGVDHRQRRIWKLKLKIKYHTTMVMLYQPSQVIRNPPPESLQVCFNSASSILQDYQMLHDMQGLHHGWRTVQNIFAAGATLIYSFWTCSVVRQSASTADLSKSLRACSGLLAVGGEWWPSVKRGQRSFGAIVDLTVRKLYTGNMPSKNPRLFMPLSSEDGETAIENSEGAPVYDATGQQSDLSHIALNGADAPWHQMAGASMELPNAHDPVHWQGVYSDPTFHSTTNDYVPEIETFLADFDKSEFSWSFPLTSISDPYDIANFPNPGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8I1</accession>
    <name>A0AAD8X8I1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RTA1 like protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_767939</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358374.1">
        <property type="nucleotide sequence ID" value="XM_060515297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8I1"/>
    <dbReference type="GeneID" id="85399195"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF17">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1708692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="282" mass="31971" checksum="D2142A689C97436E" modified="2024-05-29" version="1">MGLVHFEDGKVLFYPYTPSKAAGVIFLFLFAGISVYHVWLVRKYKTKYFMPMVLGGICDTFGHLGRAWAGSAPLSPKPFMLQLMLILVAPVFISATVYVNLGRLKETLLGHQRRKCSPTSIFILTDIIAFCTQIGGSLVQVIANPKIMEIGGHVVLGGLLFQLCVLVIYFALVMRFQRATQRETIYSQHWRRYVWTLIISVVAIWVRNLVRAVEFAEGWYGFVNQHEAMMYIFDSFLMFSVMVTFAVFHPGQSIWRHSLTGAELDEATEMHLIFSSPSGYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8T9</accession>
    <name>A0AAD8X8T9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_644939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000285">
        <property type="protein sequence ID" value="KAK1703340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357267.1">
        <property type="nucleotide sequence ID" value="XM_060509794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8T9"/>
    <dbReference type="GeneID" id="85393693"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1703340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="310" mass="33704" checksum="89DB69291995A7D6" modified="2024-05-29" version="1">MPSFNRIAIYGHRGWASSKITEALIASGAPIRIIYRPGSDISSLPASVDCVEVDVNDERALIDALHDIDIVISLVGHEGVERQHAFVKTIPKTEVKLFSPSELAGRYDEQGLKVGVNKAKRQVEEASIAAGIPTTLVLLGNFAEFALNTPGMGVDLPGNRIVYSGNSDKEIVDLCTRNYVAAAYAAIFASTPVAQLQNRSISISELKVTGEHVATTLEKKHGAPPSISSLSLERVNSEVEEGLKSGSLFTLAWYCRKIWGTGQQAEMVGNDIWEVQGYKKATVEDLIIDGKLEAYRQLPPQVAEYFQGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8Y2</accession>
    <name>A0AAD8X8Y2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_644655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000268">
        <property type="protein sequence ID" value="KAK1704180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357387.1">
        <property type="nucleotide sequence ID" value="XM_060509767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8Y2"/>
    <dbReference type="GeneID" id="85393666"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="404" mass="45430" checksum="8556D7A0DCBF2B64" modified="2024-05-29" version="1" fragment="single">SLLGYVGGQAATSAIFERFLWPQRHFSSFSIYDMPRLACLYSMAGPIGSIALEVVDTAYKNGLFSGAVQGHMLGTHFYRDLEWTYILHARGGESERESQIRNCLWVQALLNMPLPTIKEPTIRQPNDTESGKVTSEEKTKPVRARVAVSHLVLSKATDEDIGNSKISFISEEIKRVDLLCLVEIILTECVGIGIMICVAAITGSLWSIIFIIPLVLRIIGTLFALDREGLNFFPNTIDDEQTRDWEINCPAIEGKFMLITGPPSIVNQFFRHYGHPVRNRFREVIQLAVVIAFGTYFPVGLLCQVTWMPVFVQYIWTVWQVWQVLVMHFDRYTQRGTSRTTTDAAIAAKLFKNFQTSDSDRVFGSAILFGQRRNGPAVVKASLSLTVADSYADGKKFLKSKVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9K8</accession>
    <name>A0AAD8X9K8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_723770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000155">
        <property type="protein sequence ID" value="KAK1711873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359197.1">
        <property type="nucleotide sequence ID" value="XM_060512597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9K8"/>
    <dbReference type="GeneID" id="85396495"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="137" mass="15214" checksum="09A219EF569FCE41" modified="2024-05-29" version="1">MSSSLSATSLLAPVARAVHYLAARDDCADGNNSSRCEKPFQSSKIIGITIGITAAVLICGTLGVLTVLHMRRQKQERKEDEIDLEIDGDVYDHPTMGKPPRAWQPHGQNNQPGNDNPFEAERQPHQRAENPFEPERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9M7</accession>
    <name>A0AAD8X9M7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_723736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the avfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000153">
        <property type="protein sequence ID" value="KAK1711948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359272.1">
        <property type="nucleotide sequence ID" value="XM_060512593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9M7"/>
    <dbReference type="GeneID" id="85396491"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004074">
        <property type="term" value="F:biliverdin reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051606">
        <property type="entry name" value="Polyketide_Oxido-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43355:SF2">
        <property type="entry name" value="FLAVIN REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="248" mass="26881" checksum="F0CD9B711DF39ACC" modified="2024-05-29" version="1">MSSTKTILFLGATGGCGLSALRRSLDAGFTCIALCRTPSKLTSVLPSEKYPNLRVEQGNAHDADVIARCVISPLDATRFVDAVVSSIGAWFELRKMNLEDVNVCEKGMTVLLNAIKKQRTEKGVSGRPRVIGLSSTGISKFGRDTPLVVQPLYKGLLHTPHMDKKAMEELLFASGEAWTVVRASFLTNGKEQPAGTVRVGVEDPVKGVEELAIGYSIAREDVGKWMYESILQKGGDDKYVAKIATVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAS7</accession>
    <name>A0AAD8XAS7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aromatic prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_756170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan dimethylallyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360397.1">
        <property type="nucleotide sequence ID" value="XM_060514710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAS7"/>
    <dbReference type="GeneID" id="85398608"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13929">
        <property type="entry name" value="PT-DMATS_CymD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033964">
        <property type="entry name" value="ABBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012148">
        <property type="entry name" value="ABBA_DMATS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017795">
        <property type="entry name" value="ABBA_NscD-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03429">
        <property type="entry name" value="arom_pren_DMATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627">
        <property type="entry name" value="INDOLE PRENYLTRANSFERASE TDIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40627:SF4">
        <property type="entry name" value="PRENYLTRANSFERASE ASQH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11991">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000509">
        <property type="entry name" value="Trp_DMAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00036">
        <property type="entry name" value="Aromatic_Prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01162">
        <property type="entry name" value="I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>dimethylallyl diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000509-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1716003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="425" mass="48695" checksum="32701B45AC32FEBF" modified="2024-05-29" version="1">MGEMMMSNEPWDFLNSVLRFRDDDSQFWWDKTGRMFSKLLKYAGYSAADQYRELNFYSLFVAPELGPSPDCHGNVRRWRSPGTPDSTPIDFSWEWGRDNQAVVRYSFEPIGLHAGTEFDPLNRHATNDWIFKLQQQKLVPNLDLEWYNHFTRQILPHGTRTKTVDCFIEETTPKAGTVVALDIEKSGPVMKIYIYPGLKAEELGITNLELVEQSIRSLPTDQFKSLGAEPLLDFLRVGTKKYNFETGILAIDCLAPKDARIKVYIRAKHTTFEYMMDCLTLGGKLDMSGEAIDDLKDFWKTFLADAPDVLDDDAPGRASPGFYYTLGCGKAISPKVYISPNYFSKNDVDVLARLRKFFSTRRSDSMMDNYEQALNDIFGRKTLETRCGSHYYVGCALAKGQLRVVTYLSPQSFDCERDMIQARRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XB36</accession>
    <name>A0AAD8XB36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Early growth response protein 1 is a zinc-finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_724535</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000206">
        <property type="protein sequence ID" value="KAK1707725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358103.1">
        <property type="nucleotide sequence ID" value="XM_060512670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XB36"/>
    <dbReference type="GeneID" id="85396568"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1707725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="425" mass="47117" checksum="72BCB371C4B9F46E" modified="2024-05-29" version="1">MVLHGPSAPPTRVAQACVPCHRTKTRCDGQQPTCSTCNDKGKSCEWPQPRGGSKSLTDRSSSSPSSSSGLPTSGCTPPANSMVLPDHGGHPMTAPSMQHQHQHQHPQRPPTGMTTTSHAMMSAGPMPMTTMSDTLDFTTPGSILDEAMRLQLQSIYFTKFHPQWPLLHRETFETTAQPKLLMQAVMTVGLWFASWPDARNLAIKFHDSLLVETGNKLLDLLEQSRQGMLSPRMDLLPIFQAMLISTILVPYRADQSMDNVMMTHAMLLETFKATGVYDQSKINLGSQLCGHSGYPWIFKELYQRLAVFQFKLHLILQTIFITIHPALRLSRNAEPGMLRVKIPLPLMMWDGPAAHWYGMVPTDPALLDANTGDEEASLTMDNKALVPLLSWDRCLGSESDKEFIENVKPFVLDPLKDTNVFPGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBI9</accession>
    <name>A0AAD8XBI9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_593547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000220">
        <property type="protein sequence ID" value="KAK1706925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357925.1">
        <property type="nucleotide sequence ID" value="XM_060506637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBI9"/>
    <dbReference type="GeneID" id="85390536"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1706925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="500" mass="57883" checksum="C5C7E4CFF61A7073" modified="2024-05-29" version="1">MAQTNSRLDVNPGSKSVADADLHEPDLKTSIEREGSTGSLVAQASTLFGSTENEENEFDPKVEPNTHFRQTVHNSSCEDLRSVNDPWKLRNSKDHESFLLSRIFSVSRSMLSAFLPDEGRLVHHPVCKRFWGSVDAILRMKGYLSPEEALEHWHKIHMRTPCLRQAKKGRVFDDPCFVWIRRHEVEESSTIRSKEAPRNEVVSCLELFYEELLDMVDRTEELHKLVMSVTSLSDSANCHDNRPHLPNSIVEAFEQIVGLFVLKAKEISWMNRLTITPDSLYGRHAERRLMDLKRNGAAIRERVRNHLDRAKEDIILLGTSRGDMDRIIIAPIGPEFLAVALISNLQNNISKQGTNDKVDLISHYRNHTARLRFNTNRKPKRQAFVEIHALEEELEALQMVVASQQGMLRAYQRLFSPLTFKYPTTDWIYYKERKSLFKLESKCVRRQQRRLAERDRALGVLRKKVRVLRDETKQRIEILDEGHGKAIRVFTIVTLFFLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBP7</accession>
    <name>A0AAD8XBP7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_175391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000206">
        <property type="protein sequence ID" value="KAK1707727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358105.1">
        <property type="nucleotide sequence ID" value="XM_060501489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBP7"/>
    <dbReference type="GeneID" id="85385388"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232563" description="Secreted protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1707727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14051" checksum="2B91C0B2B08FCC8E" modified="2024-05-29" version="1">MGFLGFLLCHPFFPLFPFCFVGKWVEGSRATRTTDLTQGGQMKLKLKTAAAPTSSQCRPDGNMTGLGEPWRRMPSSQPYISTINRLMNAMTRNGSKGWMTKHLFFFLFSYLASARPPRQAKHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBS1</accession>
    <name>A0AAD8XBS1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General substrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_584341</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>myo-inositol(out) + H(+)(out) = myo-inositol(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:60364"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361884.1">
        <property type="nucleotide sequence ID" value="XM_060505748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBS1"/>
    <dbReference type="GeneID" id="85389647"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005366">
        <property type="term" value="F:myo-inositol:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904679">
        <property type="term" value="P:myo-inositol import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000073">
        <property type="entry name" value="MFS myo-inositol transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF22">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="45"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="531" mass="57612" checksum="A7B3BFB7BA21AC8D" modified="2024-05-29" version="1">METKDFKELAQHKETVADGSSEIQASLDGLDSIEQTQTGKFSWLVSITAAIGGMLFGYDTGIISAVLVYIDNDLGHTLSSSEKELITSITSGGAFIGAIFAGATADRFGRKIAIYVGSFLFTAGAIIQAAANSLALMTVGRLVVGFGVGSAAMIIPMYIAELSPAKYRGRMIGLDNMCITGGQLVSYGVGAGFAHVQGGWRYMVGGGAIPALILACMLPFCPESPRQLIYHGKEQEAEKVIRKIFPNGTDEQVRMKVRHITIHVEEAKNMNAGKSQWWVLKQLYVVPANLRALIAACGLMAISQLSGFNSLMYFSPTIFSLVGFSNPVAVGTIIAGTNFIFTLVNLLLVDRVGRRRILLCTVQFMGLFLVVAAVAFKWIPINHDLSLGERATIGPPAIIVLVSMVFFVAFYSSGIGNTAWLSSEFFPMEVRAMGTMMLTMSCWGSNIIVASTFLTQMENTTPSGAFGFYAAICVLGWVSIYFCYPEVKNMTLENIREVFNHGFGVKRARELQKQMKAHRNMGSVSEENVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XC88</accession>
    <name>A0AAD8XC88_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_656639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000151">
        <property type="protein sequence ID" value="KAK1712200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359318.1">
        <property type="nucleotide sequence ID" value="XM_060510891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XC88"/>
    <dbReference type="GeneID" id="85394790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1712200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="375" mass="40904" checksum="7342DDA3C262712A" modified="2024-05-29" version="1">MTFSRTLKAFTAMSSLNHFNLHRLAHTNADQNLVLADCGIGSNPENLTWSTSRQMNWYRGAIWSTPAETDPAPPDMVAEMPYNDGKYPWNYEGASATFSNGDTWSAWIEDGTPELLRAGKAMSTKDGGTTLWCYTYRGRPISMSASGNSTCVSAFICNHLETGPTPWARIPGVWVPTDNGTASTGGTNNPSDVGRTLSVKVEVSPRPAIWYGTIAHFLSSILFTTDGYCSPYSFSNRLNSTVTAHCQGTNATPLNFLPVFFNALKNLGTVPGSDGYFVYNHGPAPFANDTSDDTLTLPTTFNLTAYDMATGELKGFIGYEVHWPEPGMGIHCSECNATKFNEEYNTAIASAFDVLYPAYSEVVIESNCTFATLCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCQ9</accession>
    <name>A0AAD8XCQ9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_656168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000134">
        <property type="protein sequence ID" value="KAK1713790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359843.1">
        <property type="nucleotide sequence ID" value="XM_060510852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCQ9"/>
    <dbReference type="GeneID" id="85394751"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1713790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="16858" checksum="BE399062A05046C8" modified="2024-05-29" version="1">MAACRATNVHVSIALFSLTKASFSSDQDFPFCISELVTCSTLYDSNGSRPAAPNLGIVYDGTLDIRFRAKEYPDADTPRAVKKRDRSQPAVLWGLPETQDENKPGIPRINNATRERETFATNYLHHRDASKTPYNSSTDPSVETMKFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XD47</accession>
    <name>A0AAD8XD47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_733080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361901.1">
        <property type="nucleotide sequence ID" value="XM_060512909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XD47"/>
    <dbReference type="GeneID" id="85396807"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF86">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1720390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="759" mass="83604" checksum="7E08B8AF9BE28EE2" modified="2024-05-29" version="1">MAGSEGSEDAEAGLQTPRAQTASASASSAARKARRYGFACSSCKARKVKCSGNRPICTGCRRSGETCSWPTQTSTESRLREANARIRNLEASIRSPIRSPNDPQPELETPDTDATNAGTARSHPLSHDGSRAAEGNADTEGSLWFQVGLGEDGTVIYNGPTSRFHAGSLEETHLTGDHQDSDPKRAQIEVLQSQYALMDSVWLPLIAAKPAMNGTGVDTTLGMALLDIYWTWLHPLHSCVYRPILMMDLALGGPYCTDFLLLFIFGLAARHLPEQVTAASGVGRGDRFIARARELLLEEMTAMKPAIPTIQGLLILGGRQCAMGKSSEGWLYTGMAVRMMKDIGLHLDITKLSRLERWTPAEIETRKRLYNSAYIWDKTLSLALGRPPSLIRRPYPAQDILDKVDDQRFWKPVQATEVSENFVASLSWTTSAFCAFCRLHEATTDMMLLFSSTSRNEEFTAQMEELDGRICQWYDEIPSPLRIEDASILDQSPPPHIVSLNLLYHALHILLRRPYLSSSDTTIKEKALEVCVRHSKKIYSIHSLFSKTFPHRLMTYQVSYCIYTAATVEAEELKRASTGAERESAAARLAAACRILQQEASHTPGSGRSLDTIRRLLSNGQPRVVDVGNNLDRRHNVVSNSSENSNQLDQRQTRSLNTEMGIVQRGNTGRHRTISRKYPTAQNAPQLSSAVDAEVDDNAFFTEGASWNDDISYGGTNTGAGFQPDAFPWGVADHILGNSGMSFSGANLVWPSGSHLDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDC8</accession>
    <name>A0AAD8XDC8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pectate lyase</fullName>
            <ecNumber evidence="5">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_580551</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363624.1">
        <property type="nucleotide sequence ID" value="XM_060505362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDC8"/>
    <dbReference type="GeneID" id="85389261"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000036">
        <property type="entry name" value="Pectate lyase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF18">
        <property type="entry name" value="PECTATE LYASE 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042234527" description="pectate lyase" evidence="12">
        <location>
            <begin position="19"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="13">
        <location>
            <begin position="55"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1723569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="34445" checksum="14040224B116065C" modified="2024-05-29" version="1">MKLSGFASWALLVVAVSASPTPTNPEGHLLNKRAAITDAASIGYATQNGGTKGGAGGTTTTVTNLAQLSAAAIASGPGIIIVSGNIVGAAKVQVGSDKTIVGKTGSSLEGIGLTILGQKNVIVRNMKISKVEADYGDAITIQLSKNVWVDHCDLSATRDGDKDFYDGLTDLSHAADWVTISHTYFHDHSKGSLVGHSDSNAAEDTGTLHVTYANNHFYNVRSRGPLLRFGTAHVYNQFYDTMDTGLNTRMGAQALIQSSVFENVGKKAIFSESSKEIGYAVAIDVVLGGESQNTASVGTLNANSPPYSYSLLGSANVKAAVTKEAGQTLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDQ3</accession>
    <name>A0AAD8XDQ3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RhoGAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_652548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1723974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364029.1">
        <property type="nucleotide sequence ID" value="XM_060510533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85394432"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13277">
        <property type="entry name" value="PH_Bem3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000452">
        <property type="entry name" value="Rho GTPase activator (Bem3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="905"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="1201"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="387"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="947"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1028"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1158"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1396"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1528"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="647"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="681"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="958"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1038"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1052"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1428"/>
            <end position="1440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1723974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1548" mass="167767" checksum="C09517212C6A93DD" modified="2024-05-29" version="1">MSQLALQTQSAQGSTSYPDASGTTSTSGPPVDVSASASASAAAVASASAADAPPRRPAVAPGTHHHPRLPHQKHPLHRLQVADVSSYSPSSKDGPTTGLLIPASDPASISNSTTTANTSIAAATAASHTPSSATSPLLTPSPRSPRRPIPSPLHESTAISSPTSPFSPRSSSFFPPGARFHTYRSRTVPDIVTTPTDDFRSPVDLSGEPQTYYQSDSSCSSTPERNTLRPLAGPLRSPMSSSGGLAAASRGKQSKGAPRNSSMDSAISAISTKSQSHRGAPGSQSDPTDIEGLIKTAGSPEAVIQYLLKEKNSQSQQNAQLWRLVDKQRAMILGLNKDLERALKDKEKYRKKLKEVMSIPELTGADGSKTGSKVLKMPVSRGIPTVDVSAPKERQVVAPDSPTLDSDSQKHSPVDMAMAPYPITPPADQPNGPPSAVGALLDPSHEMPKAHEHAYDQYDHDAEEQAAEAARREHEDEQIMDLPLNFGLPPSRSLPSQPPSMPPPKPPGVSEPASAASEGISQFPAPPPRKPPPAPLQLQSQSQPGAEDDDSDSDFDDILEVDEILTEQRGRRRTREEDDQDREILAIQEAERRSLSKKSTSQSQTTSPTEGIPEAPSGLPPSPPKRMQRENIPASLGSVLSATTLEAPLLSPGLPSSPRPMGGPSSSDSPAPSVSSFPAAPLSPRPPRQPIPLPPGHSLQTPAGPEPMVLKSPQPLNIVKKGWDSASEKSRGSPTERGRIFKGFTTEEYPDLLLPPNVLPTIKVKVASSRMKPSRASLMSLTQLEEDPVFTLAIFSRSEPGELWRVEKDSASLAKLDQRLKQCPAFTAKTPERSLFSGHAPAKLDARRIALNHYLEELLETPLDTASALELCKYLSTHTLPPNADDAGSMESMAEAKVKTGPGGRPFRTGYLTKRGKNFGGWKARFFVLDGPHLKYYETPGGAHLGTIKLPSSQIGKQSQSNENQSPQPSANSDDMDNQYRHAFLILEPKKKDSTSHVKHVLCAENDRERDQWVDALLRWIDYKDPEEDEAHAAKQQTQDRQHASAAERAEKKKQRYKKTASQHHHQPTESDSLIGVRYDATSQGDLPHHGGPARPKNSGHMPENSHPVEPMGMSSQPSMMISAPRDMQVIADSAQWGNRAGLGVPVNEEKKLKKRSFFGFGPKTRSSSDGQDSLFGGSEGGSSTPPQGGYQGPIRQAFGAPLAEAVRYNHPVDVNVPLPAVVYRCIQYLDAKNAILEEGIFRLSGSNVVIKQLRERFNTEGDVNLVTDETYYDIHAVASLLKLYLRELPTTILTRDLHLEFLSVTEMTDQRDKIAAVSELVQRLPQANATLLKYLIAFLIKIINNADMNKMTVRNVGIVFSPTLNIPAPVFALLLQNYFGIFGLEPEQYELPSSFAEGETGRERSGSLPSMNNGLPNRPSYDPSQHARPSTSAGSSQSPHRQRLMDAMTGQQRTGNTPPPLLQDLQSARQSPTPPPNYPVGRGTTYEPQYMPSGYQNNNYQQMARGYDSGSSGYDPHKRRESAIFMGNMVGLNPQSSKSRLREETQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE17</accession>
    <name>A0AAD8XE17_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Internalin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_632393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000098">
        <property type="protein sequence ID" value="KAK1718843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361343.1">
        <property type="nucleotide sequence ID" value="XM_060508967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE17"/>
    <dbReference type="GeneID" id="85392866"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37411">
        <property type="entry name" value="PROTEOPHOSPHOGLYCAN PPG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37411:SF1">
        <property type="entry name" value="PROTEOPHOSPHOGLYCAN PPG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042029936" description="Internalin" evidence="2">
        <location>
            <begin position="27"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13574" checksum="7398BA0D17CD5BAA" modified="2024-05-29" version="1">MKVTVLLTAMAACIAALPTIPHSGQAQTSADESYLPMKTRAETNADESYLPMKRAETSADESYLPMRRAETNADESYLPMKRFETSADESYDPMKRAETSADESYDPMKRAETSADESYLPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XE29</accession>
    <name>A0AAD8XE29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_588085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000122">
        <property type="protein sequence ID" value="KAK1715496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360295.1">
        <property type="nucleotide sequence ID" value="XM_060506101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XE29"/>
    <dbReference type="GeneID" id="85390000"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="3"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1715496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="450" mass="49901" checksum="961B7C8A14CBA901" modified="2024-05-29" version="1">MHIVPLVMLLYLFSFLDRVNIGNARLYNLERDLNLQGNQFQVAVSILFVTYIIFEVPSNLVLKLLTPRRWIAFITVSWGIIATLTGLVNSYGALIACRLLLGVVEAGLFPGLNVYLTFFYSKHELALRVGYLFVSAAIAGGLGGLLAYGIGHMEGVAGLSGWRWIMIIEGLPTVVLGVVTYFALPNDAGSAYFLSEEEKAVLVRRRGREYGNTSSAQEFSRGDMVKAFMDWKVWVFCVAQFGADTMLYVGFSTFLPTIINSLGTWTAAQVQLLTVPCYFLGAVVYMTMAFLSDRTQKRGLFCVIFGSISVIGYGVLISPSSNGVHYFGCFLVAAGLYVVVGLPLAWLPNNSPRYGKRTTASGMQLTIGNCSGVMSSFIYQAVDKPRYIRGHAVTLSMVGMATCMYGFMWFWYSRENKQRQGGRIENKYADLSDDELAELGDESPRFRYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XES0</accession>
    <name>A0AAD8XES0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl transferase group 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_720494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363701.1">
        <property type="nucleotide sequence ID" value="XM_060512280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XES0"/>
    <dbReference type="GeneID" id="85396178"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03814">
        <property type="entry name" value="GT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="4">
        <location>
            <begin position="44"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="3">
        <location>
            <begin position="240"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="521" mass="58471" checksum="AFC51290359E9621" modified="2024-05-29" version="1">MAEPLLPKSYGTMPRYPAHDNSVFPSSLRGKRILLCTESFGPVNGVSRTTLMLVEHLRSHGALVAVVAPHNHTQHNTFSPATENDSQVEVRLQGYPLPFNPELSVVYPVRVSALFARTFGSDNPPDLIYLASPASLGFQVMLQLQQQPKERRVPVICNFQTDLAGYCAILFPHPFSTMAVFAFAMVQSYLFQHESIKTIFYPSRFVRKYLEAQGVQSSKLEVLRRGVKTEVFRPEMRSEMLRKQIAPNGEIILICVSRVAGEKGFDFLAKAVKELDARGLRFKLYVVGGNRNAEVEREVHEMFDPLREQGKVIFAGFKTGDDLATAYASGDIFLHCSITETFGLVVLESMASGVPVVARDEGGPSDIIDNGRSGYLVPPNDLDTFVDKVMYLSKDRDCREAMAAQARVMACEATWEKINNQVAWRMVDTIEEREREKAQITHQRSSIAMQARQLVPVYSWALMNNAMRDVVVGRIVDAKLVGGFGVVMTFWFFTGMYLAFTEAALWAKGKLPRYWGQRVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEX9</accession>
    <name>A0AAD8XEX9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_583444</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000082">
        <property type="protein sequence ID" value="KAK1722233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362288.1">
        <property type="nucleotide sequence ID" value="XM_060505660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEX9"/>
    <dbReference type="GeneID" id="85389559"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053001">
        <property type="entry name" value="MNNG_permease-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814:SF2">
        <property type="entry name" value="DUF3533 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34814">
        <property type="entry name" value="NITROSOGUANIDINE RESISTANCE PROTEIN SNG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042023679" description="DUF3533 domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="4">
        <location>
            <begin position="4"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1722233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="429" mass="46183" checksum="4B370CB9A8B9FD73" modified="2024-05-29" version="1">MSSILILVLVLANMSYLFGATFEQGKRTHALKILAVDLDGGAIGSAIVGASKSFQAANFPTIEFGSASKYSTPAAVKNAVCKGDYWGAIYINVGASAKLASAINGTSTAAYNAADSVTYTYNQARYPAIADSTINSNIQKVVGASRAFYYQSPNGTAALRSLNTTNLAAIAAYLNPISSTPDLIGAQTQASRVFFNTVNIIVPTLAQFFFILALNGIGMSSGLLAKMRVRDVWLIRFTIGKIYGFLTAVTVTGYLWAFRENWAVGGPEFGKTLLVFWLYMDVQWQVLESLIGSFVPMQLIPFFFLTWMLTNVASSVFPFEIMAGFYRIGYAFPAHEIYSLLVQAWTGCADQTRVALPVLFSWWLVGHVGSVFSIRKRCADAAAIVAAGAAAAAAAKAPAQQDDTVSIPPRSASTEVTLQSDEEQVRNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF49</accession>
    <name>A0AAD8XF49_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_583035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362528.1">
        <property type="nucleotide sequence ID" value="XM_060505612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF49"/>
    <dbReference type="GeneID" id="85389511"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1060.10:FF:000006">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="7">
        <location>
            <begin position="17"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="184" mass="20593" checksum="9768693CEE966DDB" modified="2024-05-29" version="1">MSITPPAPVSLPEGAQKATIAAGCFWGVEHLYRKHFASKGLIDARVGYIGGDLSNPTYRAVCGGDTGHAEALQVVFKPEEVSYRQLLEFFYKMHDPTTANRQGPDTGPQYRSAIFYHDEEQEKIAKEVTRLANEQWYKGAIKTQVAPAGQWWDAEAYHQLYLDNNPGGYECPSHFLRTFPPLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFA3</accession>
    <name>A0AAD8XFA3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_654849</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000097">
        <property type="protein sequence ID" value="KAK1719351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361435.1">
        <property type="nucleotide sequence ID" value="XM_060510759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFA3"/>
    <dbReference type="GeneID" id="85394658"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000002">
        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="11">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1719351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="124" mass="13458" checksum="F4B5DE38DEF255A6" modified="2024-05-29" version="1">MSESAAWPLADDALQQELLDMVQQCQHYRQLKKGANEATKTLNRGVSELIILAADTNPLSIVLHLPLLSEDKNVPYVYVKSKTALGRACGVSRAVIACSITSNEGSELAGPIRALKDKIERLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFG3</accession>
    <name>A0AAD8XFG3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CST complex subunit Ten1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_305872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365407.1">
        <property type="nucleotide sequence ID" value="XM_060502279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFG3"/>
    <dbReference type="GeneID" id="85386178"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024222">
        <property type="entry name" value="Ten1_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12658">
        <property type="entry name" value="Ten1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="127" mass="13724" checksum="EDEE702DDAA33389" modified="2024-05-29" version="1">MSRGPLPSQLCLLSDLPSRPQGDKVRFLGCVTAYSTHSAVLTLEHSFPKGSNISVLVDVQLLLSTMPSNQTRVGEWVNVVGYLTPAPPGTWAKGTTREPRIAAVQALMLWSAGPLNLQRYEASFATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGX2</accession>
    <name>A0AAD8XGX2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="11">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_721039</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="11"/>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362995.1">
        <property type="nucleotide sequence ID" value="XM_060512343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGX2"/>
    <dbReference type="GeneID" id="85396241"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007956">
        <property type="entry name" value="PRK10675.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="13">
        <location>
            <begin position="6"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1722940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="372" mass="40819" checksum="7DD40B97BF955C9C" modified="2024-05-29" version="1">MAIGTVLVTGGTGYIGSFTSLTLLQNGYDVVIVDSLYNSSKVAVDRIELLSGKRPHFYQVDVTDKAGLDEVFKKHPEIDSVIHFAALKAVGESGEIPLEYYRVNVAGTVSLLQAMTDNDVPNIVFSSSATVYGDATRFENMIPIPEHCPIGPTNTYGHTKAFVEQVITDHINAERNKLKKAGKPYEQFNGALLRYFNPCGAHPSGLMGEDPQGVPYNLLPLLGKVATGDRDKLLVFGDDYASRDGTAIRDYIHVVDLAKGHLSALNYLRENKPGVKAWNLGSGRGSTVFEMIKAFSHVVGRDLPYDVVPRRQGDVLDLTANPSLANKELNWKTEETLEKACEDLWRWVSNNPKGYRQDPPPELLANAKPTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGY3</accession>
    <name>A0AAD8XGY3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_623145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364478.1">
        <property type="nucleotide sequence ID" value="XM_060508366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGY3"/>
    <dbReference type="GeneID" id="85392265"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041897418" description="MFS transporter" evidence="3">
        <location>
            <begin position="21"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1724423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17533" checksum="7BE01021BF824DE9" modified="2024-05-29" version="1">MNRKSILLLLLCSFVALVSANSAPTFCKCTCFKNSTIVALGPQHADGESPGNAPPSSRDSSSSSLLNKRAASSSCSQCTKAFCLSRGIDFCSKAKDEDVQTMCFQRDSNKDRVIVWGFLLGTSGLLGWAVFKRANELREGKRAADAAAASGGRGDYSQLSPARPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI38</accession>
    <name>A0AAD8XI38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_221043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367256.1">
        <property type="nucleotide sequence ID" value="XM_060501751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI38"/>
    <dbReference type="GeneID" id="85385650"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1727201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="260" mass="29692" checksum="AAFFFC20A816AC34" modified="2024-05-29" version="1">MSSNGQGHDDPYHSSSWSGYSQPGSWNSTPRYTPSVSSYASSSSASQVSGSSYGSQSHYTHSAGGLMPYDEFGMPQAYSDTPAPSQYSAISTFHQGIVQQQIAPPPSNNMLYCEFQPWTGCREQFRLDDVDSWIRHTEDIHLRGAYPAVCVCWFCDDFNFKVSQRCPDPGENWSQRMRHIAHHMLHDAYRFEQRRPDFSLLEHLYHYNRITPQSFQQAISASEGPRTQNVYPSGWRPPREEADVIVAGNGRRRRNQGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XI85</accession>
    <name>A0AAD8XI85_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_776421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365783.1">
        <property type="nucleotide sequence ID" value="XM_060515463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XI85"/>
    <dbReference type="GeneID" id="85399361"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="74"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="321" mass="35507" checksum="0A060FB840BD1A7E" modified="2024-05-29" version="1">MAVVPPPGCEHCSRSQIKELGSVARAANQTYLTRSELDTTLLVLNIRADDTAQAENIQTVLWTLVVLSAVFLGLRIYCKISYTYTKIRIEDILLVASWLVLASDAALNEFIIKSRFGRPDFPITVDNITVLAIVGLSSITCSFVGQVWSKTAFAISLLRMCDGWKKAFVWFSIISMNVLFAFSSLSFWIGCVPLEKRWKPFAEGTCYDLKWVVSFGIFVSVYSGLLDIALSIIPWLILMRPRPAEESSGLTLSKKEKIGVSVALSMGMLAGIAAFVKASYMRSVNDTTGDFSRKWGSLLNDRFSSNASYRWGSRVGSLGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIJ3</accession>
    <name>A0AAD8XIJ3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_749831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000022">
        <property type="protein sequence ID" value="KAK1727786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367841.1">
        <property type="nucleotide sequence ID" value="XM_060513825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIJ3"/>
    <dbReference type="GeneID" id="85397723"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47783">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="670"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="863"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="874"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="915"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1028" mass="113406" checksum="76E8A47C053A3970" modified="2024-05-29" version="1">MTSIVNGATPAPKQIRFVTNQGHPPSKRRRINAACLTCRKRKTRCAGERPSCSTCAKNGHTCLGYNEVIEKKSSSGAIATRDPHHDEDDDVEEDEDEDEHIREEEGGGGGNPDKRKYGKNTATGRRLSGLKSEGEQPPKTVVETNAGHSPTFLRRSSEHSSRDQDQSSGPRRPSHPRATSFSDDARSTQSRSPVSHHTDRHRVPYFRYFGPTAIVPGYKQMVVSVRDRRRSTGGSAGATSPSSGSSVVQSMGMALSGIPQHEEVAVADEDLPVYDPNDPAPVHPLVLHLVKTFFLHLGCNYPFLKEDNFIRMVKEKRVEPILVDAVCALAARFSDSPQLGHSKDEEASHAEQGQFYAHRAKAATVDTFPCPSVGAVQALLMMAYEGFGADQDSALWMYLGLAIRMAVDLGLQKMVGVIYQGERDPWYTRHGDQASSDAGATDGPQEDDNGLTREEQLEVEQERTDTFWAVFVLDRVISSGTGRPVTIRDDDFELALPVSTLDPASGWPAPFPVFIQIIHLYGRVSDVLNNIRNANDLTSEKWAKLSRMEHELTKLYQKQDPRLHFSVSNFKTYLKLGQGTNFILLHFWFHALIIILHQPTLLTPFGSLRSTHQLLPNSRELSMSSAKTIADILAFAELIDPKSFIGNPFTSQPMYIAACAFLMESIANASNPTSRETSPPNEPKMEGQRQKSSSHEQRMSTKHSLLASAANQNYSRCYKSLQQLHKYWGGVKYILTALDQKSKGIWDCETYTNEEYESARLPRRGSIGGRFPHPSTPNMPPIAWSLTGTTNSPNSSLTLMYQNMHASQSGHHGTMQPQQSNIPTSAPTPPGNMIYDPIRQSLPEAAPQSIFATAYPQPLISAMRQTSRSHHTQRLSTSSMSPTNQGRGHLQFEGIHEEQTSPPARHAGPMLAATSHPQQPTSFTPSSHNSAGYDHSMMPSVSPSGNMHDAVSQQHHNGQHIAFDPTYANATYSYLGQGMGPITDVITFENPIDIGALGLPNEMMPPWLEYLPGDVLGLFENNNMDPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XIK1</accession>
    <name>A0AAD8XIK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_751029</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366248.1">
        <property type="nucleotide sequence ID" value="XM_060513996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XIK1"/>
    <dbReference type="GeneID" id="85397894"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="166"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="658"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="839" mass="93487" checksum="1F8F03D588BBB305" modified="2024-05-29" version="1">MREKAPMRDTFFGIKAEPQRPTSVATEFMDMEWDDDVLSEFEDNSPRISVNSSGGQPSITTLSSYDEVQTPRSSQGRMMYATEMMESPNKNIEGPSGPHLFRASTASYFDEAILTLSPVTPKTARPFDEPFRHIRPQQPPMPPSRLQSGPFQFTYEEFESRELVSWTPEMVAQSMLNAGIELSVAGRFVENDINGPILITLKFEDLKELDIPSFGMRTRVWNQIQVLRDSRPSSPRAPTPIQDEPSREVKKETREVRAAERQQTDDCGMKRSKSSRRRPKKPSHDDIITPMESVSIVGIEQVVPKPHQCPKGENCSKWRKQQRLIEAFKKEHPFVDLDTEQVVITGNPGNPQTARALDPTQILRPISDAVPSVVASSDVLGPGNATPLQYLQEAALRNVVARDPQDNVRQFLDFQKHEDTTVPPTPPFEMGFPAMKAQPERLRHLPKLSIPGKQAPRASPLRASTVPPPSAHPEPLPTPPYQQQQPQGFVPYHMDRAEAMSPDLQSPINNPYRFGTPFSEMDVPVTAVPMDRIARDVSQSVPPEMNYRPGVSKQQQPPLSRTQSRSSARRPSFPVLPALNENTATPIARTSPRHTSPRTSVRPQPLQQQQPLQAPPRVNYPWSPIERTTPFEQAIPPITHLAPSLPVKQAASAAQQDGVTFQGPMKKRKTKMLRHEWNDTFCTLKGTRLAVHKDAKTVDRTLEYVDVDDYAIACSSLASQSKLSAAFKAVHFSSSSSHSREKSDPVAAFSFQLIPQDKDKESAGAKLRKRGSALHGFGHGHSSSSGSIPAEGANGTGKTHHFAVKSRDDRIDWMRELMLAKALKQKGDGFEVSVNGNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJK6</accession>
    <name>A0AAD8XJK6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">3'(2'),5'-bisphosphate nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_549328</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000017">
        <property type="protein sequence ID" value="KAK1728368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368423.1">
        <property type="nucleotide sequence ID" value="XM_060503475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJK6"/>
    <dbReference type="GeneID" id="85387374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000015">
        <property type="entry name" value="3',5'-bisphosphate nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="22406" checksum="407485FF480F4C3E" modified="2024-05-29" version="1" fragment="single">MSSYAKELEVAQLAVQRASILTKRVFHEKAKGTVDKNDKSPVTIGDFGAQALIIAALRHHFPDDEIVAEEEAAQLRSESQLRDQIWDLVKTTQLDDAAAEASLGGGIASAESMMDIIDQGNSKGGAAGRIWAIDPIDGTKGFLRGGQYAVCLALMVDGDVKVGVLGCPNLPVDDKAPLAADIGSNANDDTGYGVIFSAVLGQGATSRPLRTGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJR1</accession>
    <name>A0AAD8XJR1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_750230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367270.1">
        <property type="nucleotide sequence ID" value="XM_060513896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJR1"/>
    <dbReference type="GeneID" id="85397794"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347">
        <property type="entry name" value="RING/FYVE/PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46347:SF1">
        <property type="entry name" value="RING_FYVE_PHD ZINC FINGER SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1727215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="37104" checksum="405E2B6EADC5EB86" modified="2024-05-29" version="1">MDAAKPQWNWPSDLPTGGPARKSHFEADLPEKTEPIKSEDHDQHDRDQPQEQPQSPPKQRYYGPRTCRICFESVYPTFEEPSVMSGFMNSRPRPVYKSDDPDSGRLISPCKCKGSQRYVHEGCLQAWRYADSTATRNFFACPTCSYSYKLERLSWANRLQGTFAQIVLTILIFIVSVFILGFIADPILNLWTDPMGAIADMAANVLDDIEAIHEPVPEMGAEPGTWLEHFLKGFFSLGLLGFVKSLFAMSPVQWWNLRSSGILSTSGRRGGTGRARVENINLGLVVIGAATFLWGVWKGVRKFSASALQRASDRVFDVGGDDDEDEDIKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJT7</accession>
    <name>A0AAD8XJT7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase class I and II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_572148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000023">
        <property type="protein sequence ID" value="KAK1727590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367645.1">
        <property type="nucleotide sequence ID" value="XM_060504475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJT7"/>
    <dbReference type="GeneID" id="85388374"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="4">
        <location>
            <begin position="245"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1727590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="671" mass="74317" checksum="1617E8D61C9FE054" modified="2024-05-29" version="1">MPRRIANPFSNAHSPAMPFSEKERRPSRSGNRITNFFTSPKGVKDKDHQTAQQALLAMQQQNISSTQITPSTISLPTISLSTATAGEPDTTEPPTTLFSPPSAVETEKKRRFDAQFGPLLHPTHRYVSKSNDGKPLDPPIIDEPPYYYILTTYISYLLLILFGHARDFFGKRFGDKKHYQALKPQNGYAPLNEDFDNFYVRRLKMRIDDCFARPITGVPGRYITLMDRESRDYNRTYNYTGTHTETLNMSSYNYLGFAQSEGPCADAVEECVKRYSLSTCSPRADVGTSDLALEVEKEIASFVGKPASMVFSMGFVTNASSFPALVSKGCLILSDELNHASIRVGARLSGAVISSFKHNDVVDLERKLREAISQGQPRTHRPWKKILVAVEGLYSMEGTMCDLPGVMALKDKYKFYLFIDEAHSIGAVGPRGRGVCDYYGIDPARVDILMGTLTKSFGANGGYVAADKSIIDKLRSSNAATTLGESPAPSVLMQILASLRLITGELCPGQGAERLERIAFNSRYLRLGLKRLGLIVYGHDDSPIIPVMLYNPGKMPAFSHAMLKRKISVVIVGYPATPLISSRVRFCVSSAHNKEDLDRLLAAVDEVADQLQIRFSTGIAGGQEPLPEGITPETEAEWRKANGTEGMYKAPRWKLEDVIARGVQDAKLRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK28</accession>
    <name>A0AAD8XK28_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368881.1">
        <property type="nucleotide sequence ID" value="XM_060510183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK28"/>
    <dbReference type="GeneID" id="85394082"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="283" mass="31139" checksum="C2DDA538CFF5F528" modified="2024-05-29" version="1">MVVAVKAKWLKTTTELQTCLGVNIKSCFNCQGHSATKSSCGNAISQASRSEMAFVMLDIINCGSLASASAHLERLASLTLCKRSHQAQAGEKATHWKARIQIYLEAGTGDGVTDEKEVKAPRVRPQRTTMITPPSTPVANKRDVRQPVSTRSSQRTAAPPPPVTPRRATRAPRGSASSIAVLIEEDLGDNSEEDDSEGEYSEEDSEEDSEEGEKYYEPEPVRSQTRRAPAPAPSVKWEPNGKAGFPYPYPSQTKDRENLEYKLAKAQAELAVYEAWVKLRKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XK75</accession>
    <name>A0AAD8XK75_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Developmental regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_85656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368935.1">
        <property type="nucleotide sequence ID" value="XM_060515957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XK75"/>
    <dbReference type="GeneID" id="85399855"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="37136" checksum="A049065C5F884CC1" modified="2024-05-29" version="1">MPTYLCHGFRWDRRSIRVFVVVQNIDDAAPEWIIAPNSSPAILESFYSLFDFLPEPIPDETEAQRDKKKRNKSKASKAAALRNEYDVPASTVPPEEDDVLQNDWSAVKLLEEYDPTDLSYVSRPYAYVADHVVRIDLSNSITEEIMRYEERLSETKAMASAPSDEFYKAKKSSSGKKAGWFEKLRDQLQRGEDIRWYIVVCGDEVRDFPEDMGAARAEQEELEREADNATPRPRDRSAGPSTSRGGASPREYMSSVPASQFATAMSPQQLSPKEAGLPYGTLPQHPNMVGNWTEKETPTLQSKPSMDFRPKTPKGGGFRRLFGKKGDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKL4</accession>
    <name>A0AAD8XKL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_569240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369166.1">
        <property type="nucleotide sequence ID" value="XM_060504168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKL4"/>
    <dbReference type="GeneID" id="85388067"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05188">
        <property type="entry name" value="MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000481">
        <property type="entry name" value="Alcohol dehydrogenase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="16"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="361" mass="38869" checksum="536D107EB7849809" modified="2024-05-29" version="1">MPHSITVKKIEGKPGKVYYPLQLNEVPKPTPGPKDVLVRLTAAALNHRDLFIRRHLYPGISFDHPLMADGYGIVVEVGKDADKGLLNKPVLITPSRGWASSPDGPEDIRQFSVIGATQTYPDGTAQDYLALPQDEVELAPEHLTPAEGAALPLVGLTGWRALVTKSGNAEKGRNILVTGIGGGVALQVLQFAVAFGCNVYITSGDEAKIEKAKSMGAAGGVNYKKKGWEKELQAQLPKSRPYLDAVVDGAGGEIVGKAVKVLKPGGVISQYGMTVSPQMDWLMQAVLKNVELKGTTMGSREEFRDMVAFVREKKIKPVVSRTVKGLTNLEGIDGLFKDMEAGKQFGKLVVEFEEPSVSPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL05</accession>
    <name>A0AAD8XL05_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_606158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369375.1">
        <property type="nucleotide sequence ID" value="XM_060507364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL05"/>
    <dbReference type="GeneID" id="85391263"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF4">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="294" mass="32263" checksum="5953DD6D91A0FA0D" modified="2024-05-29" version="1">MFTVRQAIGKGLGVFASKPILTGQRILTDQALLTIISSDSNSILRQAQLLSTAGRDSLLSLSTNPGKSSVFSWLESIWRSKSAPQHTVSNHTILNIFRNNNFNIGNQTQALFSQVARLNHSCVPNAQGNFNKDLNAFTIHATRNIEPEEEITISYLDEHLGLRQSRQTALHHGYGFTCGCSACSPTTLSEAGEVRRAEIQRKLELFAEAASEDPEDEFKMMLALLDAHEAEAIRGREVSTMYIATARKAFDLGKREEGCELALKGLQLEKEAVGDDSPFYAASLEAVHALGVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLA3</accession>
    <name>A0AAD8XLA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_31575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369464.1">
        <property type="nucleotide sequence ID" value="XM_060502335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLA3"/>
    <dbReference type="GeneID" id="85386234"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1729409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="150" mass="17454" checksum="AA8A07512B9AA4A5" modified="2024-05-29" version="1">MKQKWAALLGALWGSIAVAFGELLRRIFQGTENKQDQMIDQEPNNELDERCYHTTHRMSGSERHFPQPWVRGLRVRMGSRVHFSLLPECPSPPTTRTVWTLWSLPTGIPRPDHRHGRTKKPGSCRWSQTFPRYNSPTKRCTVLTRIPMCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLB5</accession>
    <name>A0AAD8XLB5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heterokaryon incompatibility protein-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_605347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369555.1">
        <property type="nucleotide sequence ID" value="XM_060507333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLB5"/>
    <dbReference type="GeneID" id="85391232"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF10">
        <property type="entry name" value="TOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="228"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="705" mass="80828" checksum="36BD881B3EA27F09" modified="2024-05-29" version="1">MNRESNQSSTRDGTTKRTIQFDDNPPPKHRQLHHPTLTYSNDTVLCTACKNAFSKEAVKADDFRRRRRNQHHESSEDLANAVEKGCYFCERFARHSADPGISTVLNEDIILHPRPDPVRLFFASSEQHTGRAWREDDLDDLVCFNLLKRSPDDEPPARLSPRMDSQETFGTMMKWLNDCVRNHPECRVFLSHSTWLPSRLIDVGDPGSHLWRIIATEHHQTPANYGGYLTLSHRWGSSPFVQLTSDTLPRFQNYTAIESLPKTFRDAIALAHHFNIRHIWIDSLCILQDSPLDWKKESSRMDDVYSNSTCNIVAAHSEGPNGGLFRARDPSVLESFVVCSERTDIPSGEYTVWDHTSILNDYNRAPLYRRGWVFQERLLPKRTLHFGKDQVFWKCRRRLTCESLPDGIPVAPDIDVVEREKGVIRIRRMRPQEEEDSPEDDKTFATVWEHLVEEYSGCSLTYEKDKLAALDGMAGIFSNASLSRYIFGIWDTHIARQICWSLNPAAEKKPRPAHPAPSWSWASVQGKVSFKAIVNSDESILHLARHFYHSAHSDTPAGRRIPLGGYIGMSGSVYTLKVSDISNDGVSLDLDGKSERLDYNPFVFDFYRDDLLPMELVILPLICTREPPVNARGVEIAGLILHPLGRIIDDCEGMVFRRSYRYERVGFFNFRPCDGKGQQLLYGSHFTEAEKIKRPYNSNHRILLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLL8</accession>
    <name>A0AAD8XLL8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_605634</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369628.1">
        <property type="nucleotide sequence ID" value="XM_060507340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLL8"/>
    <dbReference type="GeneID" id="85391239"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="198"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1729573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="362" mass="40094" checksum="94A268B2978831EC" modified="2024-05-29" version="1">MSGHPIPNLLSLRGARGGRVGRGHGRGPGGGPSSSGPTHDQTIQGTDDDAAGSRLSAVNVGYLADPYAHFFVDNINGPPPRRLPIINRGTYTRTVALDNLIDSFLDESDSAQPGSNERQIISLGAGTDTRPFRLFPRAKRPRLVYHEIDFSVTVRKKARIVQAAPPLRNILGVPSVEEDGSWSCQPSASDKYYCHARDLREMVQDGATPLAGIRTDVPTLLISECCLCYLETSTTKQVVSLFEQKIPNLAIVVYEPIRPDDPFGKMMTSNLAARRIRMPTLEDYKLPQDQMQRLSDAGFEHAKTLTVERIWESWVPSEEKERVDRLEGLDEVEEWKLLADHYVIAWGWRGAGFTMGNADGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLU2</accession>
    <name>A0AAD8XLU2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_15049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369757.1">
        <property type="nucleotide sequence ID" value="XM_060501323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLU2"/>
    <dbReference type="GeneID" id="85385222"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="194" mass="21136" checksum="09C8D3DDC52B7345" modified="2024-05-29" version="1">MASPKTPPVSDDTHTPPAKIDGHRERLWLFAIASPHPAKHTHRALHLTAVERATSPYLRAYMATVRRLQLLEAIDKGNSVQQTAALLIQSKMCDRHTQIDNPGRARGPDPPPLVVGRAHARVPEPAPPSHCMRSTARRTARDACQFFLDQDGAFHSCAAQGTSRKRAFMPLSISLEGDGSVCVSLGRVSTARQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM23</accession>
    <name>A0AAD8XM23_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_567705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369901.1">
        <property type="nucleotide sequence ID" value="XM_060503977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM23"/>
    <dbReference type="GeneID" id="85387876"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000115">
        <property type="entry name" value="Salicylate hydroxylase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF238">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G01680)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="314"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="463" mass="50676" checksum="3EA64074D9D80CDF" modified="2024-05-29" version="1">MEGHTQNSSNNDGIHVIIIGAGLAGLTTALSTKLANPSHRVTILEAVKELQEVGAGLQLTPNATRLLEAWGLFPALAPLATVPSTLSVHRYDGTRLLAHEPRLQETIQSRYGHPFWGLHRVELQRALVDRCTALGVDIRLASRVRSVDFASATVTLDQGSDSSSPDSTSTVSGDVVVCADGMWSATRAQFLNRPSPPSLTGDLAFRIAIPIDSLKGPHKAELEAFIKSETVHFWIGPQGHGVSYTVKQGRMLNLGLLSPDNLPEGSTKVLGDVEEMRGLFSSWDPLLRKLLDQVESVHKWKLCWIEPLDEWASKDGRFFMAGDCCHPMLPYLAQGANSSLEDGAVLGHLLGKVRGRATGTEAEESSTSTSTSQLAAAAAMYQRLRMARGQRIVMESFAQRDDFHMPDSPEQERRDEIMTASLAPGEEPRSGFPSRWTCPDIQHFLYSYDAYAEAEAAYKQDPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM99</accession>
    <name>A0AAD8XM99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_647483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000009">
        <property type="protein sequence ID" value="KAK1729927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369982.1">
        <property type="nucleotide sequence ID" value="XM_060510081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM99"/>
    <dbReference type="GeneID" id="85393980"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="111" mass="12382" checksum="559E0416F235F6DA" modified="2024-05-29" version="1">MDVGQTVVVSLLPLVCRLGILVGLDIGSHRYRVEVALATIYLCPVRCFNYVTVVRLFIRGFTEDMTLPLQNSACYKWSIMYECHTAEGPKRDAGHFRGATNSLGSWELLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XNZ9</accession>
    <name>A0AAD8XNZ9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="4 11">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_601021</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="4 11"/>
    <dbReference type="EMBL" id="JAHMHS010000005">
        <property type="protein sequence ID" value="KAK1730890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370945.1">
        <property type="nucleotide sequence ID" value="XM_060507071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XNZ9"/>
    <dbReference type="GeneID" id="85390970"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="12">
        <location>
            <begin position="85"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1730890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="614" mass="68091" checksum="A1BEF5C13DA43145" modified="2024-05-29" version="1">MVLRRADDAFMALLRSYHSQRFCSAALGVCGRSAAAAAVVPARRSFSTTTVVARQERQRSQKEAEPIFTKNIQVPTDIAVVGSGIAGLTTAHYLAKLLPETSNITIYEAGDRVGGWINTQELEVEVNGKKSNVRFERGPRTLRGMGKDTWKFDDLVLFDMIRDLQMQGEYLGIKSPPRYIYYPDHLVEMHPRNVFREAAFKGIIPGFLNLMWRRQKAREEVKPADMSVADFIATYTGRPELTNNLASAMLHGIWGGDADKLSMRSFMAGPWHRFFDKPYKEDDYVSYPRSEVGIMATLGQDQELRQYLKSAQKDQLVFFEKGMSSLPNTIAEHLRRRKNVTFKMGEPVTSLEYDNKGKKVMLSSPSSTSPTPYDKVISTTTSKALHAATGGALPSLANSPNVSIMAVNLWYPQPNLNAAHPGVGYLVPRATDSNLEGLLGVFFDSDVVPRAPDEPEGTKFFVLMGGHYFDGLPDDALPTEAEGIEMAKAVVERHLGIPQSTPAFAMASLAKDCIPQHHVGHYKRMAHASYELRDAFKGQLTVAGGSYTGIGVMGALRAGYDVAVHIAQSAQEHVGDTGLEQFDSSAEIFSSPRWQLREIGRDIDDKIGWRNYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPT0</accession>
    <name>A0AAD8XPT0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pathogenicity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_565152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371408.1">
        <property type="nucleotide sequence ID" value="XM_060503718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPT0"/>
    <dbReference type="GeneID" id="85387617"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1731353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="45499" checksum="9E44C7DF026D31B8" modified="2024-05-29" version="1">MAPSPAPHDRPSFPSDLAPASSAQHGASSPAQQRTLAPTGTPNATAHRSGSGSPRGAAQAPKSSPPSAARHASGAPKIVVKKEPNSPDLPTTRHRPRKLDLSNKGAHPGSNTPGTARPMTARDNLGIQEVGLACLSPGFVTQDPVMKEQLQRSMSVRDQQRMIIEQRMQQQSAKGDGPDTSGKDPVSQFAAKTPGLSRRNKAQLSILPPSAESFANERVIQSAPLGHSFTGRQHPAPLSRHITNQPNTLSNTSHIHHVPANQTNNRLPPISDVFGQVSGHPDNAPTSLYPQTSRPPMASPGHPPQMQHGPPTSGRAREYKSAEEAQHEIAGGRPELLPKIVHYGNAHQPPTPPSPAPGSRAADPSRSASRRRTRAEYEDGSPPLGHGPAPQRRGPFGAGRDSPESQRQKREEFMQLCARAWDLFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPX3</accession>
    <name>A0AAD8XPX3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_243963</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371311.1">
        <property type="nucleotide sequence ID" value="XM_060501891.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85385790"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="10">
        <location>
            <begin position="94"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="443"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="714"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="921"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="983"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1288"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1398"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1484"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="405"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="927"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1000"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1290"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1307"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1334"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1355"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1398"/>
            <end position="1408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1731256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1512" mass="167841" checksum="E0E89237B32D1E00" modified="2024-05-29" version="1">MTSDANPHQRSSSPLKRRASSMDPDADVSMKEEDVEMASTNHHQQQQQQQQQSAEGAESAPASSNTHLPRAMSVDLPDNVAKGASNKSNDKDLPPLEDQIKTIQTLLKAFNDEPPKVGDVAYVVSRSWVEKALALGGDPKFAKKETINEPLGPVDNSDLILEVLSQPSGDDFVRMKPGTGMEECELFPEDAWTLVSEWYGVGEGQKPIVRSAINAAPDSTSEKNVMFELNPPVFTIHRLWSMASPFKIKDELKSKEPLVLARSATTPYNPFYKELKELTGVPLDRKMRVWQLTQQPEAQESSPRSALTPPDSPNPDKDSESSSGPWQRMLVEVPSFTKVNGGDRQLVPAVDNTSNPNYNGNSPLSVYGLMQDMTLVIDEEIAKNAWVSTYFKNGKNDKVLASRGSATSLKANSSGRSSPAPQGPITRGRTQQKKKPGRGLGAVGLQNLGNTCYMNSALQCVRSVEELTKYFLTDKYKEELNKGNPLGYKGQVAMAYGGLLKEIYNESRGAVSPRDFKNTVGRARATFQGWGQQDTQEFLGFLLDALQEDLSRIHKKPYIEKPDSTDDMIGDEEAIRKMAEEVWDITRKRDDSVIADLFTGLYKSTLKCPTCDKISITFDPFNNLTLPLPMEDMWSRPVKFYPLNDVPVKFEIELPKHSAIELLKKALSDKTGVPVELLMGAEEFKGKFFKVYSDATSVSEEIQSNDIPAFHELESSPTNYPPKQKKMGTPSSMLEISDEPWVDPRTERLLVPVLHRKKTGNTYRSRGDDIAAPPHFIVVTPEESRDEDVIRRKVLEKVATFSTWSEFEEIDESTDADMVITSQSDADSSGDSKVVSNSVEGEDDLVNVSVGAGEQQQTRRPTLKQFNIRRPKWANPKEYLPPHLQNLFELSFFGESNDYGLPVGWNTVDDNKSFRLLSSRAPELPNEDSNSPGSTNGADSEHESVSEETTPQSVDEQTRMAEESEEDEPVRVIKVYIHRASATAGEAAQANITQPMNRGRGNHKVGGARRKNNKGNKTYGKRGGKRRNRDSRNSKEQSFHVVDVEPQPSPEDDVRGGPLVRLDEGIVVDWSEETWDLVFGKESVRDTDDNRGSKTFTEPEELKDPVLEQKRKSRMARKKQGITLEECLDEFEKAEVLSEQDMWYCPRCKEHRRASKKFDLWKTPDILVVHLKRFSSAGWRRDKLDVLVDFPIEGLDLHKRVLCQETGKEEIYDLIAVDDHFGGLGGGHYTAYGRNFVDGQWYNYNDTSASKTSPESVVTRAAYLLFYRRRSEGPLGGPRFKEIFDKFDKDGEDDDEEDTDSGEDQRLVGGSSLTGSSRLGIGAEATHPRGNRGLASNTMSTANPGAEDELPPYEGSSSTNVGSDNIQNSIEDEGIGMTDYNGDSTAFSATQGWNWNSLDSADGNNNSLGLDGYGSDDAQPDSSDEREVGNDTDMQFDETMGDYETAHDEAPPPPDFGAQVGLSEIQTAAWARQNNAEVISVPAADEDAASTEAAEIHLDDDAEAHGQTTRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQJ7</accession>
    <name>A0AAD8XQJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_746539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371668.1">
        <property type="nucleotide sequence ID" value="XM_060513287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQJ7"/>
    <dbReference type="GeneID" id="85397185"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF7">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="110"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="28539" checksum="1BCB1E867F127D44" modified="2024-05-29" version="1">MDRQTIIETNRSLRTIKNELENLLEKGVISEDAYDSMHATLPAETPLHGAASRAAPAAAATPVQHNNPTSPPAPTAAMAALNVNPSASPAPPSYNQTGPPSLPARTNEKPVLAHARALYRYAGADARDVAFERDDRIAIHEYMNADWWMGRNLRTGQEGIFPKTYVLVEQDMAKGAFAPVPAPAQPQYAAQQPQWAPQPQYAQPQGPPPQQNPYNADAPPQAVADQSTGGKEGGGKGAEMGKKFGKKLGNAAIFGAGATIGSNIVNSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQL6</accession>
    <name>A0AAD8XQL6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_10892</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371997.1">
        <property type="nucleotide sequence ID" value="XM_060501074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQL6"/>
    <dbReference type="GeneID" id="85384973"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1731942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="779" mass="86660" checksum="B605FA24D04EF3CE" modified="2024-05-29" version="1">MEQSPEDHQSPPDGQAANRGSDALPRPRPLACTPCRRRKIRCDHKTPICSNCVRYGLECAWPEGRRSSGRRQRPLYEDVVSRLAQMERLVEELQKPDQGPTPPQQYVPTASEAAKASASNASPLATTSSNNPSPLSRRKASSASPSAGNPDNYPSPPSATSSASTGARPYYIGAPDESTIIAAGACSLLSPQGLSQIELLIGDSRFSNALKAMQPKVVYDNVQPYLEHADTNHPLPPNHVIMECVNDYFVTMNTGIRLFQEHEVRAALKSYFQGMPPADPGWRMAVNVIIAHTLRKRNVMRNKEEYQKYIHNALGMLPNIILRTPSPLAIGALLSTVLYFSFTSENHIALTLMGLTVQLLLMAGYHRPEPDVAFARPQQLIPTEHLHRRRLFWHAYVIDHDLMLRIGKPALISDDFLLDLPEEHPSDGYSMYYYPNDVTLNFFLEQVRLAQIQGRISTTLYSRSGLPAAELEAEIRRLDNELTEWRQSIPPMIRADNVDALLDGDYSRLVCLTTLHFTYFQLVVAIHSAAFRLPTLEDQEGVESGDIGPSLALCVSASRAAISLLNYHQIEHPYTPYLLYQIAWSVDILFVNILQNKNNPRARRDLDLIRTVISFFEKYDPYHQSVISYQIIKVIADVAATVLANTPTLPPHMLPVQHGQAVQQVPLPAPSMPIMPDSSGAMQGAFSPQMSGPGTARSGSINGSTPDVLGSMTSLSMADQQQQQTSPFMDLSAGLASPNNGQLFPGFMDMADWRLPMDYQPELWQYDNLLDNRFPNNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQZ8</accession>
    <name>A0AAD8XQZ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_787091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371999.1">
        <property type="nucleotide sequence ID" value="XM_060515659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQZ8"/>
    <dbReference type="GeneID" id="85399557"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042074514" evidence="2">
        <location>
            <begin position="18"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="31"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1731944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="546" mass="59761" checksum="F13D697E97C212EB" modified="2024-05-29" version="1">MKLVILSLLASVASVRSAASNTNSSHSNNPLTVRTSTGTFTGIVDPDAPNTLQWRSIPFAEPPVASRRWLPPAKLQPNNTTRPQYATKFPPSCPQFVSSVESMWNLPLTKGNLIYNGAQNDTSGLEGEATSEDCLYLAIWKPTTPPPTKAGFPVLFFMTGGGFIMGGIDLPWQIPTSWVERSQSAIIVTINYRVNIFGFPNARGLATEGISQNLGILDQRAALEWVQENIAAFGGDPDRIMQWGRSAGSVSADIHAYAYYDDPIAQSYYMESGVAQSGIEADTTFSNFTFVAQNVGCGSPCGADCEDEDGTAELDCMRRVSPTQISNFIGQYTDRGEAPAIFFSLVQDERIIFRDYEARAAEGKLARRPVLISLTANEFSSLVPWPKENLTEGPWQPLVTEADVVWVCAAYAATVARNQLSTTEAPVFRFQYAAEFPNLNVYDWLGAYHNSETPLVFGTYGLLDHIAPTTEFEVEVSHAMQDRIMAFAEDPYHGPQKEFGWQPRIVSEANGGDVLRFGAGGKVVERIDGVDMDSVCTGLGEYDPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZN4</accession>
    <name>A0AAD9CZN4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_607050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000013">
        <property type="protein sequence ID" value="KAK1729189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369244.1">
        <property type="nucleotide sequence ID" value="XM_060507406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZN4"/>
    <dbReference type="GeneID" id="85391305"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00488">
        <property type="entry name" value="PCD_DCoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF0">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1729189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="208" mass="22542" checksum="5D4C36F9C04AEB34" modified="2024-05-29" version="1">MSTPARTLVRRIAHCTPRPLTSTPSRLSKAATSPSPLQNFTQLSAPRHQRTMSTTPATAAPVPTPRFSKGSDEPSLSSTLETLLGQGRGWALVNDGEAVERSFKFKNFAKTWDFMTAVSLQCKIHNHHPEWSNVYNTTFIRWTTHSPKGLSDKDLKLALICDALAKDFGEVEVPASEATTDTEVVSCGIRGLADKAAGTAGDCCTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CZU4</accession>
    <name>A0AAD9CZU4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_605457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369587.1">
        <property type="nucleotide sequence ID" value="XM_060507337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CZU4"/>
    <dbReference type="GeneID" id="85391236"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="209" mass="23585" checksum="9F31B4075EA73D28" modified="2024-05-29" version="1">MLRAYGWFLESTPILPSLSNPLPHRLHPTSGPHRDASRIDNHGQEGDGVPLCNKIRNQTARQRRAGRRAEEKGSGRGGEKRTSWPARRLVRHARLPERKKQRCQSRSTLHHSSRITPTANLTLGRMLPFFAHRFPFASSISPPPPQTMPPTSHPPTTGRNQSQWVSIPLWSEPFLHATVLILLTDSYRPAPLSGRLVVDPRKSIANRHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D1K2</accession>
    <name>A0AAD9D1K2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_747289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000006">
        <property type="protein sequence ID" value="KAK1730507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370562.1">
        <property type="nucleotide sequence ID" value="XM_060513409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D1K2"/>
    <dbReference type="GeneID" id="85397307"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF230">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1730507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="512" mass="58344" checksum="701BDD59EB3D012E" modified="2024-05-29" version="1">MVTVNLPEHIQAQLSRLPALPAVNTAITSLCLIATYIFCRSFYYLYLSPLRHYPGPKLWAISRLPWNYVNMKGRITWRIRELHDQYGPVVRIAPDELSYTSSTAWKKIYGQRTPSEFPKALDGRGIAPPTMEGRKTLMTEDQAGHAKLRRAINPAFSERALREQEYYFQNYTDTLVSQLKKVCKEGAVDLSTWFNLLAFDILNDLAFGTSENCLNNADQLWLRLINTRAKAYVWIQLTVQYGVFDLLTWIAPRRVIESRRKHIAMTEAKVRQRIEATTPGKDFMSYILNNPEAGNKLTNIELTMLAGTFIVAGSGTTAGGMSGLTYLLLHNPEKLEKVQAEIRGKFSTQEEITMVAAQNCRYLRACIDEGMRLYPPTPGSLPRWVPGEGEVIDGRWVPGGYAVAVNQFAAGHSEHNFRRPQEFIPERWLELGPDSEFAGDDRAAVQPFSYGQHICIGRAMAYAEMSLTMAKLIWNFDFELENPAEDWWSKQGTYIMWEKVPLMIKLRPRIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D279</accession>
    <name>A0AAD9D279_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-L-rhamnosidase C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_746584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371223.1">
        <property type="nucleotide sequence ID" value="XM_060513292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D279"/>
    <dbReference type="GeneID" id="85397190"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872:SF1">
        <property type="entry name" value="ALPHA-L-RHAMNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35872">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1731168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="39957" checksum="238B24B33EC4ED0A" modified="2024-05-29" version="1">MSRPDSSLDSSEKDRNAPLDHPHSDQSTTETKFSDSNNNNHHEDKKQDVEGRIPTSAASATVATAEHELYEPYDNGYHFPPAHTKSQSMKIGAKAFWNYTCTPLGFFVVLYGLNVVAWGGMLFLLLCNASPAMCYPTCNDINSPRRKWIEWDSQILNALFCVTGFGLAPWRFRDLYFLMQYRILKKSEALGRLAGIHRGWFRLPGSDQLPVHIGPENVTELANERPVLHIPHPEKAIPNAPLTGVRAPPTAIWKMDFVIWFNVWNTFLQCVLSGFMWGMNRFDRPSWSTGLFVALACLAAAIGGLMMFFEGKKVKSIEGVPLSKEDEERLAKDKEMGVHHYNNIKDKKPKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5T1</accession>
    <name>A0AAD8U5T1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipocalin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_593702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000224">
        <property type="protein sequence ID" value="KAK1706612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357867.1">
        <property type="nucleotide sequence ID" value="XM_060506654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5T1"/>
    <dbReference type="GeneID" id="85390553"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin-like" evidence="1">
        <location>
            <begin position="12"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17024" checksum="6AFB1A776CF5B588" modified="2024-05-29" version="1">MQPTEILAILAGTYQLLNTSATRDGVAVPDRTYGSNPVGILSYSKSGFMSATITSTDPEDRPANLTFPFEDSQSDADWALVGKHSIGYAGPLRISEAFPANATFGQVIHGPLTVANVPSMAGGSQARNYTLYEDGKILRISSQRDGGNRGELWWKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U5U3</accession>
    <name>A0AAD8U5U3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inner membrane transporter yfaV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_643174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000217">
        <property type="protein sequence ID" value="KAK1707128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357976.1">
        <property type="nucleotide sequence ID" value="XM_060509658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U5U3"/>
    <dbReference type="GeneID" id="85393557"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF32">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="68"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1707128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="514" mass="57184" checksum="8E3A7D7ABE4C0271" modified="2024-05-29" version="1">MTRPLSPGKKITVSVSLVLSPCAHDKMSESKQESLQSIDSRGQVTPGIEPDWTRHEEIRARQKIDSSVLPLLYLGLLVFQLDRMNLASALTGGFAKDIGVNQDTINLGNQLMFLGIVILEIPSNMLLQKIGPRKYISSQVILFGFVATMQVFLVDRKGFLASRMMLGLAEAGYIPGACYTLSTWYTKKELAKRIAIFFFGMFSGNALSPILASGILKLEGERGLRGWQWLFLVEGVFTIFVGLSLLFLLPGSPDIPDPLLSPGLIRFKGSEKSIIQRRLEIDDKEKRGGAQGMRIPPKLVWKTVLHWKRWPHFLSSFAVFSTWSPLTTYTPTIIMNLGFNRIQANALAAVGASLALVVVFIFAYISDKTNKRGLSVIGAQFCYLIVLVVARTAHPHVGKWSRWGLWTAVNSFAVGYHPVNNSWVQLNCREPGERSISIAMWVMLSISGLMVGTQYYRGNDAPFYQTGLRTQIIMVSVGMAFAVLQVVIYTVHNKRVAGGKHKPRVGEARRIYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U7H4</accession>
    <name>A0AAD8U7H4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_593893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000229">
        <property type="protein sequence ID" value="KAK1706134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357782.1">
        <property type="nucleotide sequence ID" value="XM_060506673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U7H4"/>
    <dbReference type="GeneID" id="85390572"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32161">
        <property type="entry name" value="DPP6 N-TERMINAL DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32161:SF8">
        <property type="entry name" value="DPP6 N-TERMINAL DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042167003" evidence="1">
        <location>
            <begin position="22"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1706134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="667" mass="72898" checksum="5ABCC45CCD25C797" modified="2024-05-29" version="1">MRSSLPFSLLCLCLATSSTSARHVHQLRADFNLASLPQAHSARGLPAADGKKGVLLMNRIGPSTSELYIANADGTNEQKLLGNASSFEYHAAFSPDGKHVAFTTERNGDGNSDLYRCSFSAAGTGNSTSASCSNLEELIATPAVEDAGALSPDGTKLAYVSTENGYRANIWVLDIATGARRNLTNTPEIAGDPLLPDGHFRPSWSPDGEWIAFASDRNTAWRGHGNGTGWEHTQELSVYVVRPDGSGFRQVATKTGYCLGSPKWSPDGKRILYYEITTEQTWDAHRPESLAAAISQIVSVDFETGEDRIEHTSGASVKMFPQWLADDGTSDEPNSNNIAYLIKGGDNEGYNYTSRAHSPVKAAIRSPAWSPDGRFVIYEKVGFTARAMEKPLYSWDADWEYRSTDVFPQLSLQGRLVITQKQLGNSSIVSMNPDGTDLKLVFDSSKTGEIDAALVAKGLAGAFQPAWSSDGQWIAFGLGSWFQSRATGKARVYRTTSNGSFYEALTDGTVHSGFPSYSPDGRSLVFREWGVRYGLRVIDLETKTVRSLTNATDNLPFWSPDGERIVFTRKTSATNFDVCTIRPDGSDLQTLTSSGANDAHAVWSHDGRILYSSGMYGFRDEAAIYDQTFQPYGQIIVMDADGSNKRMLTDSLWEDSMPLYVPNQFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U8Q2</accession>
    <name>A0AAD8U8Q2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_595821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000328">
        <property type="protein sequence ID" value="KAK1701941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357082.1">
        <property type="nucleotide sequence ID" value="XM_060506825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U8Q2"/>
    <dbReference type="GeneID" id="85390724"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF382">
        <property type="entry name" value="ACYL-COENZYME A OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214063" evidence="1">
        <location>
            <begin position="20"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1701941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="501" mass="54421" checksum="954A1D4F5AC3E7CC" modified="2024-05-29" version="1">MTAFVIATIHLNLCVGTIAKFSRERPDLMATLEELLTFKACGEFMLTEVGHGLDARNLETTARMEADGSFTLNTPNAGAAKAMPPSSPLAGMARVAVVFARLIVGGDDRGVKPFVVRINDARGMCDGVVSRVLPVRAGTKPLDHSITTFHNVRLQPEALLGSASRADNEREEFLAHIWRVSVGTLSLSIMGVSAIRVAGCIAALYSQRRLVGDRKKLPIMQFSTQQRPILEALAHGEVLHAYAKWSVGEFMNQNHNADVRRGIATVFKVLVVRSSRLLRELAERCGWQGLYAHNQITELASTFQGNAVAEGDTLVISIRRSSSLASELLMNRYGLPQPTDPTGSLAMYEAGMLEEVARDKNLALGVSGSLRGTTYNNSVLPRCRAMVEAIGQRMAYEAAQAQGNIAPEVIDVFEKSCIQKDPSWFVEHGYGTRSALRDNENGAYSNLLPLLPTLVERANAEVYITAPLVEEGAMEDFIKALPAFGAGADDVIVEQAPKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U949</accession>
    <name>A0AAD8U949_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_637325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359802.1">
        <property type="nucleotide sequence ID" value="XM_060509303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U949"/>
    <dbReference type="GeneID" id="85393202"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17324">
        <property type="entry name" value="MFS_NepI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42910">
        <property type="entry name" value="TRANSPORTER SCO4007-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="141"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1713749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="598" mass="64560" checksum="19DB7FFB58359004" modified="2024-05-29" version="1">MLEKRNSAERRRGDTDASSNKDMGSTPTGAGAGATAGPDEAAVVAAEGKEAFMSQEVIQNSTANSTQDGGLGGDDDEKRVFTGGGNDTRSPSPSPSNSDCESHRDGGEKGGRKGIVGATVGFLTWTPRKLRYDPKNPPQFTLGLNFLFAVAATFTVANLYYNQPVLNRIAETFNVSFERASSVATLMQAGYAAGLLFICPLGDMLRRRPFILGLIWVTAMLVSNPKITSRKPHHPNTIQWLGLCLTNSFQAFLGLSFIVGATTVTPQLMLPLVADMAPPERKASSLSITTSGLMLGMLIARLLSGIVANYTSWRNIYWFSFGAQNLLLVLLFFFVPDYPSTNPDGLNYFRALWTIVTMLFTEPILVQACLIGFFISSIFTSFWTTLTFLLASPPYEYPSITIGLFSLIGIAAICGGPVYGRLIMDRYVPWMSSVLGQTVILIGCIIGAFTGTFTVAGPVIQAICIDMGIQTAQTANRTAIYTINPKARNRVNTAYMVCVFCGQLTGTAVGNRLYAQGGWKYSAGTSIGFIGLSLIITMLKGPREKSWIGWSGGFKLRKDAPKPQPASPEEAQGPVEEPVEEPVEKRTDIGAGGEENRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9Q7</accession>
    <name>A0AAD8U9Q7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_591781</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000178">
        <property type="protein sequence ID" value="KAK1709752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358663.1">
        <property type="nucleotide sequence ID" value="XM_060506474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9Q7"/>
    <dbReference type="GeneID" id="85390373"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF96">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="37"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1709752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="39738" checksum="1CE9CFA2B5E12B17" modified="2024-05-29" version="1">MSVVPRDDSLPPNEDVGPISFSLALALTIFLVITTGLRLWARSANRKLGWDDLTIALAGATAIIRFAFVVLQWKRGNGRHRVYLSDHDYMIINMYGWWGQMLLFISVAFLKVSICLLILRIKDSKVLKCLLHVIMAGVLITNFGVVIILIAECQPIGFWRGKSAVCWPTHIRIYFIYATIAYSVLTDLICSLLPLVVIWNVKIPRRTKISVCCLMGLGLVATGFGVARAASLGISTSDLSWAYCIAGIWSNLELFLGIIAANLALSRSIYVYFLGNGDAQQTLPGSTGRCDPLQSGYLDSNLRGDRFEVPSTMIGSPRRRGSETRSSDSDILLKLGIQKKTEFWWTEDDEGQPQKQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA03</accession>
    <name>A0AAD8UA03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_736142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000234">
        <property type="protein sequence ID" value="KAK1705944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357723.1">
        <property type="nucleotide sequence ID" value="XM_060512988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA03"/>
    <dbReference type="GeneID" id="85396886"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042146678" evidence="1">
        <location>
            <begin position="18"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1705944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="251" mass="25518" checksum="B08C3EEC49C61E2E" modified="2024-05-29" version="1">MLAKNFLLLASLALVSAAPAKRQAGCVSKPTAPTLPVNGNGVELPAPAADLVLKHIALGHGIQNYTCTSVNATAITATATGALAGLYDAQPLYPATGPASLASVDIFNGLTTNAVWSTPLPLTSDGTTKFGASATSPFPAKADLVMPGIAPMKQLGVHFFDNTGVPTFQVGEDLFRGAKLNGTKAPASADVGPEKTGSVDWLLLGDKGGSKGVTAVYRVVTAGGVAHQCTTPGATDSVPYAAYYWFYGPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA04</accession>
    <name>A0AAD8UA04_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Actin-like protein arp-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_590705</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin family. ARP6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000158">
        <property type="protein sequence ID" value="KAK1711564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359117.1">
        <property type="nucleotide sequence ID" value="XM_060506360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA04"/>
    <dbReference type="GeneID" id="85390259"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10210">
        <property type="entry name" value="ASKHA_NBD_Arp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000040">
        <property type="entry name" value="Actin-like protein ARP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.36.70">
        <property type="entry name" value="Actin, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1711564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="448" mass="50088" checksum="FC3645040D2F78D4" modified="2024-05-29" version="1">MAGGRNTKSSGPVPPSRTLVLDNGASTIKAGFVSDDHTDEPRVIPNCIARDRARKVYVASDLEKCHDFGEIQFRRPVEKGYIVNWEAQKEIWDHEFFDDKAPQKCDPSETRLLLAEQPNSLPILQANCDQIIFEEYQFASYYRGIGASFNTYHDIQGILQTPRDPNSVPQIPAEAVLLIDSGYSNTIVMPLLNGKPLHSAVRRLDVGGKLMTNYLTRLLSLRYYDMRNDTYIVNEIKEQASYVSLDFNGDLEKTWKGTRGEKREPYVTGAGIAKDYILPDFHTKTKGVVRDYDPAMHTKARKMAARAADNDEDILTLRNERFSVPELLFQPSDIGLRQPGLADVIMQSLSELPIGLWPGLLANIVVVGGNALFPGFIQRLEKELVKRVPDACIVRVAHPVDPITSTWHGGAKLANHSDIHKLSATKQEYEEYGGAWVARKFGCGNTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UA84</accession>
    <name>A0AAD8UA84_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_54441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360372.1">
        <property type="nucleotide sequence ID" value="XM_060503436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UA84"/>
    <dbReference type="GeneID" id="85387335"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="62" mass="6995" checksum="DC5ED8CDB11DFA74" modified="2024-05-29" version="1">MRTTRPIWLPDSGSKQDEGAPNSTACPGWGSALALNYNHHFDAVTTPRHGKFRRFPSRLETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAY6</accession>
    <name>A0AAD8UAY6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_641657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000187">
        <property type="protein sequence ID" value="KAK1709130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358469.1">
        <property type="nucleotide sequence ID" value="XM_060509569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAY6"/>
    <dbReference type="GeneID" id="85393468"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1709130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="36403" checksum="47BBC266CB37FCCE" modified="2024-05-29" version="1">MGLHGRYTTEKVTYPSHGETITGILYKPKDIINPPGIVVLGPYSFIKEQAPLQYATRLADEGYAALIFDPRTVGESTGQPRRLENPVMKNEDVVSGLDYLASRGDVDAKRLFLVGVCQGGPECLDVASYDDRVVAVASVTGYYRDRETDIWMICSGCVNVEPGVDVGSLKMPTPEQGEALYQARIQRARDAKALYEKTGEVIYQPLVDPKAADPDVGSLAGLPGPVTWSWYGPWTMKGFENRYAVMSDLDHFGYSTVAGVAKLTKPVLVIHGDNCMNAAAAKRHYESIPTKEKKLIWDNEISHFQHYEQPDVVDRNVREIAAWFGQAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBD4</accession>
    <name>A0AAD8UBD4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase FSH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_684282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000191">
        <property type="protein sequence ID" value="KAK1708687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358369.1">
        <property type="nucleotide sequence ID" value="XM_060511239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UBD4"/>
    <dbReference type="GeneID" id="85395138"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF4">
        <property type="entry name" value="ESTERASE ALNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1708687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="305" mass="32775" checksum="0C19951FDDCC1F92" modified="2024-05-29" version="1">MRILCLHGYGTSGAILRSQLDAFIHRADASYEFVFLDGEYECQRAHGIGKFAQPPFRCFNQSFGPHAIQSSLDHLQDFIDDEGPFDGLLGFSQGGSLALSYLLQMAETMAANPGTPPAFSFAIFLSTIVAFSPDPDFCSHLITGLTPSDRENVLAGFPRGATHNDYAALAGAPERAIFFSSLGKVLEKSIVGGFIAPDTPLGLEALLHPASAATNNDIDHLPRLMHPVIASPGCKVPVPTVHVVGALDDPLLVSMSKVMEGLCVATLTRSLVHDGGHDVPRKPRDVQALWSAVEWATREAAKQVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UBT7</accession>
    <name>A0AAD8UBT7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="14">SNF2 super family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_585842</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000100">
        <property type="protein sequence ID" value="KAK1718772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361272.1">
        <property type="nucleotide sequence ID" value="XM_060505879.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389778"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13907">
        <property type="entry name" value="CHD1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="11">
        <location>
            <begin position="267"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="11">
        <location>
            <begin position="366"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="464"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="766"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1043"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1308"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1054"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1308"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1319"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1334"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1366"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1384"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1413"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1454"/>
            <end position="1477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1718772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1599" mass="182463" checksum="8E55523751EE188A" modified="2024-05-29" version="1">MSSPLEPGPTNGYGSPEGGSPSPIVAAGHQSDSDLSDMHDNAARLASSSPSPDPNDLSGYLNGAPDFAESESSGDENNASDDADFDMDEDAASVAQSDGAGDVHSDSNDSQRPTKRKAPAREDDYIKANPELYGLRRSSRPTQQRRMVDSSDDSESDVVPTNRRVVKKRRVETSRQSSKRGTPARQPSTNSDSDSDNYGGARAKSLQKKARRQREAQPSALLAEKRWSSRRAAQVQQGAYEESDVDDEDEDMLTPNYYAADVVDDSPYIDKVLRHKLKDGLELSWSSTRTDFEYFVKWQGKSHLHDTWETAETLRSMRGYRRVENYFRTIVEHELLIRYGEDIPPETKEQFFLDRERAEEALEDFTKVDRVVAVRDGDEETEYLVKWKGCYYDECTWEVASAISADFQDKIDQFLDRSSRSWVSDRKESNPDTRTRMTKLESQPDFIKNGELRSFQLRGLNFLCLNWTRANNVILADEMGLGKTVQSVSFLSWLRNEREQEGPFLIVAPLSVIPAWGDTFDNWSPDMNYVVYLGNEASRSTIRDNELMINGNPKKPKFNALITSYEMILQDWQFLQQIKWQALLVDEAHRLKNKESQLYARLVSFGVPCKILITGTPIQNNLAELSALMDFLNPGKVVIDEELEDLAGNDTQEKLQDLHKSIAPYILRRTKETVESDLPPKTEKIIRVELSDVQLDYYKNILTRNYAALSSATGQKNSLLNIMMELKKVSNHPYMFAGAEERVLAGSTRREDQIKGLIASSGKMMLLDQLLTKLKKDGHRVLVFSQMVKMLDILSDYMALRGYKFQRLDGTIAAGPRRMAINHFNAEDSDDFCFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMGRAHRIGQKKPVSIYRLVSKETVEEEVLERARNKLLLEYLTIQAGVTDDGKAFRDEMNKKGLKIDGPNSAEDIQLILKMRSQKMFEQSGNQERLEQLDIDSILENAEITKTKVDDKMNLSSGGIDWDNFMQYTDVKVDDLALDWDQIIPAEELAVIKADEEQRKNEEYVAKVAAESAPRRATMKNRNETDRSDRLAKKRQREEQQRREAEEQRALLSDPKRPLNEKETRNLLKAFFRYGSMDDRGEEIVQEARLGERDRDFLKSILDDFVKRCEDALNDNNTRLMDDERKLGKSLTKKDKKAVLVDFGEVRKMNAETAVERPQQLRLLRQTIRKSDDFKTFRLADATKAAHYSCEWGAREDGMLLVGIDKYGFGAWTQIRDDATLDMSDKFFLEEHRIEKKEERNKATEKGVNSPGAVHLVRRSEYLLSVLAAKHSSDPLAHRTVENHHRNNKRLANGHRRSDVGSGAASPAPPALKKSGSHRDRERSHADHHRSRSNADEKGTPRPDSKRKHSGHDEGRIPKHRRTEEARRTKSNGDEQQSPRADRPRHRDEGERSGKHRRAEDHRHGDDRRRSSNTPRANQPDNERRNQALHRLDQLRKMGDNKEEREKDADAMLWYLLKPVRANFEAILVTTKERIKSSKERAKIFGEELVVIGNFLDREFVQERDNALKNRFWEFLANLWPVDSTSNEVTGDRLSAMYRVLRDREVKKHNGDKPAAAAANGTAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD34</accession>
    <name>A0AAD8UD34_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_785376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361756.1">
        <property type="nucleotide sequence ID" value="XM_060515629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD34"/>
    <dbReference type="GeneID" id="85399527"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="44041" checksum="E7AF72F2465EBF41" modified="2024-05-29" version="1">MMNAASIDLALMDFASMDDAFIARFLQSHVHGPIPGRESGPNPVAVALKPVFLRLMEQRFTPKGSKGNPDPDSLTVLHEMQRLQDAFLSREGPRLLISNSKPSMLDLEQLHRRLTSYPKRLPDSDYHKDLDQKIPLVQQINQLCRQFHTDASMKELHLDKASFWSMLMTMDLERLEEVRRDLDDMTSAKAKRLLLTDFPAWSMATPMLLRSRMSYKGMRKSLSGSCTQLGRWVTCPNSNLNKAVLTFFPRKARLRDCKRCIITERSFDSDVVRIIPLDLLRSRTHMVKQLEGMRSRYSDDSVTALLKKLTSESCDENIIDTRRNMICMDRSMDNHWYTGEFILKPMGRPVQMFVPFPAEDPAEEPQVKGVWVLKLIFYWLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UD99</accession>
    <name>A0AAD8UD99_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_796674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000146">
        <property type="protein sequence ID" value="KAK1712594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359451.1">
        <property type="nucleotide sequence ID" value="XM_060515875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UD99"/>
    <dbReference type="GeneID" id="85399773"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="380"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1712594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="748" mass="83905" checksum="E04692E7F459E57E" modified="2024-05-29" version="1">MGLDQRHKRDADGDTDTSNPTHPTLNTIDFNLQIGVEEILTDVDPDVSLEFLQKAEAHSGKPPPTRISREVLISTHNDYVEQQQKSGQQNGPRMVKKVVLALSYPPSVKSVVDLSLMRLDELLVENHHEDKYVVLRTIVQPYAGAGTITIVEDQYGNVDKMALYNQGNSTVLQSIPKGSVVIVKEPYYRYSGDTDFMLCIDHPSDIVLLRQGPDDALIPEIFRKVPEFETAADWKAAGDRAFISKNLPLAAANYTRALELELEGDTSFRVDVLLKRAGINLTLKCFDRALSDALSSRGASSDWRPHFIAGKAAYELTDFQTSKQYFESALVLKPEAGNIRKEYERCIARLEEEKGNYDLADMTASVTSKNIHIDRASFLSRTEVRDSPHHGRGLFATEDIEAGEMIFAERATSVPNEFNPEHNAAAAYSQLVELCADNPTIHNKILDLHGGSYKRTGQEGTLVGGRPVIDVFLLESIRRKNCFSGAQVSAQSANPEWNMWKQGMSRGLWVYSAYANHACLPNANRSFIGDMLIATATMDIPSGTEITHIYLPPKAAYLLRMPQFRRSWGFVCSCALCAGESGSSAEQHQKRNAALAEIEALVRRKRPTKFYPDATIRQVEKLANKLANLHEKEVYDDLSLPRLMLVWPTMWLVEVWHTRKQWNKVVKWGSEVFRNFGFVEPVRQGRLWMYKDTQAATTFEVIRALKWSAEAYTALGEEALARDCLDAARIGLKTMVGFVTDDTFAAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDQ2</accession>
    <name>A0AAD8UDQ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol dehydrogenase</fullName>
            <shortName evidence="6">HDH</shortName>
            <ecNumber evidence="6">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_636919</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="JAHMHS010000133">
        <property type="protein sequence ID" value="KAK1713826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359879.1">
        <property type="nucleotide sequence ID" value="XM_060509281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDQ2"/>
    <dbReference type="GeneID" id="85393180"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000026">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF14">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1713826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="434" mass="46686" checksum="521978619DA03038" modified="2024-05-29" version="1">MVQYLKSKATTNGTNSTSPLDVPGIVRGVIDDIRATGDKAVRNYSEKFDKWSPASFKLSQSDIDSIVSEVPAQVIADIKTVQSNVRTFALAQRDSLREFELEIRPGVFLGQKNIPIDRVGAYIPGGRYPLLASAHMTILTAKAAGVPKVIACTPPINGEIPPSTVAAAYHAGADEIWILGGVQAVAAMAIGTETMDKVDFIAGPGNPFVAEAKRQLFGEIGIDLPAGPTEILIVADDKADPTTVATDLLSQAEHGPDTPAVLITNSRTVAQKSLEEVDRLLKILPTAPLASVSWNTYGEVIVVDSLEEAYALADDYASEHVQILTERPREALEKMRNYGALFLGAKTCVSYGDKCIGTNHVLPTKKAGRFTGGLWVGKFLKTVTYQEVVSESESGELGRLCGRAARAENFEGHARSGDLRAKQFLGDEFEWLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEA0</accession>
    <name>A0AAD8UEA0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_636158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360149.1">
        <property type="nucleotide sequence ID" value="XM_060509235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEA0"/>
    <dbReference type="GeneID" id="85393134"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042087874" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7429" checksum="6698ED7944F23D74" modified="2024-05-29" version="1">MVLYILILPSNLFAVPTLSLASDFSVSMSLKPGQTTIELTARIRAGPEASQAFPPVPCMPNPKTVWPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEG0</accession>
    <name>A0AAD8UEG0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Family 26 glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_754225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000076">
        <property type="protein sequence ID" value="KAK1722687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362742.1">
        <property type="nucleotide sequence ID" value="XM_060514451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEG0"/>
    <dbReference type="GeneID" id="85398349"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006080">
        <property type="term" value="P:substituted mannan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04086">
        <property type="entry name" value="CBM35_mannanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022790">
        <property type="entry name" value="GH26_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000805">
        <property type="entry name" value="Glyco_hydro_26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40079:SF4">
        <property type="entry name" value="GH26 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40079">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16990">
        <property type="entry name" value="CBM_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02156">
        <property type="entry name" value="Glyco_hydro_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00739">
        <property type="entry name" value="GLHYDRLASE26"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51764">
        <property type="entry name" value="GH26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042052480" evidence="5">
        <location>
            <begin position="22"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="6">
        <location>
            <begin position="31"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="GH26" evidence="7">
        <location>
            <begin position="172"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="472" mass="52095" checksum="B882F44CFB27AA91" modified="2024-05-29" version="1">MARYTALSLRAVLAFAAGAYSQNCIGSTGAKVYEAENGVLNGTTVATEQAGFTGTGYVTGFEDATDKFTINLDCQGEGQKLFDLNIRYAGIYGEKRTNVILNGGAASEVLLAATETWANVSAGQVLLNEGNNTLDIVTHWGWYLIDSITLTPTEARGPHNVNTALVNTKANADANALYTYLRSIYGKNILSGQQELNYANWVNETIGKSPALVSVDLMDYSPSRVERGTVGTAVEEAITHHERGGIVSVLWHWNAPTGLYDTEENKWWSGFYTRATDFDVSTALADTTNANYTLIIRDIDAIAVQLKKLQDAGVPVLWRPLHEAEGAWFWWGAKGPEACKKLWALVYDRLTNHHELNNLVWIWNSVAADWYPGDDTVDVLSADVYAQGHGPMTTQYNDLITLGQDKKLIAATEVGSAPFPDLLQAYEAHWLYFCVWSDGFINNTEWNSVDDLKKIYGSEYVLTLDEIQGWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UEG9</accession>
    <name>A0AAD8UEG9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G protein-coupled glucose receptor regulating Gpa2-domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_708979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360051.1">
        <property type="nucleotide sequence ID" value="XM_060511565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UEG9"/>
    <dbReference type="GeneID" id="85395463"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF37">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR GPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1714589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="543" mass="61007" checksum="6E5CF309CF3A8D9E" modified="2024-05-29" version="1">MAFDAAVASVTLTGSILSFLATTGVLISFALYHEHQRSFRHALVLNLTLAEFINSLGNTISGIIYIKNKELQPGAACVLNGMVGQLSVQASDFSILAIAVVTFLTITRKTYMPNASTFRKVMICLSVWVIPLITSTTATLMGTMKPVSGNWCWITRERPDLRYALTHGWRFGIIFTTILIYLYVWWYLGRHFRTMVSTSDPLYNSENSNGNVVTSSIRKKQGFESIHTPELEMDQFERANPTWGELPQFSPTQQAQQTSPVAPRSAPAALARRPSATEVDEDKEVQVQVGGRRPSAVRMAHFAEDKIDEEPTGEQEPGRKMSARISRFDDHDMDMSQASEARFSYLEQEDKLHKSASGGPSHLQKDMLPPAAIATQAQFAQYRMDSGPPRRPSVSIWKKTHRSRSSTLSALSFKMPGTREMQSRDFPTNPTLNHVDSRKSAPQNVTATMMSDFPIRTQTRKVEREIKRMMLLNAYPVMYVVLWIPGLVNRLMEASGNGSQSRVLAALQSSSQFIGLANAITYGFNQHVRHRIKGDFFTWLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFA3</accession>
    <name>A0AAD8UFA3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_630840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000089">
        <property type="protein sequence ID" value="KAK1720366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361877.1">
        <property type="nucleotide sequence ID" value="XM_060508859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFA3"/>
    <dbReference type="GeneID" id="85392758"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF48">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1720366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="506" mass="57281" checksum="EF6869E2A2DBC742" modified="2024-05-29" version="1">MSPAPQPSLSPEIPEKRRCWECQRRRLVCDSVKPVCNKCRASGIVCPGYDDRKPLTWLAPGKITCRTRRKGRLVDKDTAAKRMKTKPKPNRPGAIEDTEALTRSKNKYGGELIFHSTLRTDICDVFEAVQYFNDVFYPYTKSGHSPTSNVFIAEIPLKVVKYLPISIAHNLVGIVYHHRMHVQKEWKNDCPSILYAQHRMHHHRGLSIRAINEDLANPKTQSSDVVLTGVILLLQSEINACITPQWRQHVDGLLAILACRGGARGWAMSEPYRQGLLLSFIIVMTSANTTSPPDDQVTICDHEEFIELIQELYPLGLHPHIPCPMPLFLEISRINHLRAKVSKKLMGKSTANAVAEDIVARIESFDGTDCDSFYEDRDDRDLIAAIFHSAVAVFCISSLQSVGTLPRSHRLTMLRTMHGNRLYSLMEETRNHPQLKKSVQWPLVVAGIEASVRVDKRRLVAELYLEQAKDIATPLPLHAKNVMRTFWDGDATNWDACFDQPYAFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UFE8</accession>
    <name>A0AAD8UFE8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_721031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000072">
        <property type="protein sequence ID" value="KAK1722931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362986.1">
        <property type="nucleotide sequence ID" value="XM_060512340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UFE8"/>
    <dbReference type="GeneID" id="85396238"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="478" mass="52947" checksum="53F9BC26AB2A6F65" modified="2024-05-29" version="1">MKDFDGGRERVMSRNVTRNVINNDPVTAAPPGRSSTKLPILTVYLASQKTYIVNSPELIALISRRSKEVDGNVPFVTIVYGKLFAFSQTDISELLRNPLQKGSLRQEAHAMEHSLLSPGSLSLKEVYEEIFNGLANHVNNISEGPRTIALQNWLQEIFTISTAKALHGPDGPFTNNKELLQAFWDFENGLKALTMGVFPTITAAKPAAARQKIVDALLQYFGDSFPENTASELIRRTRRLALDHSRGPEFIARYGLGLMTGFLINTVPAVFWIILRIAKDEDMLKKVRLELSLIIQPCAHDESFSTLEVAAIRKSCPLLMSICHETLRCISSSTGTFLVHQDAEIGDEYILKKGAIVQMAATAIHSNPDVWGADADAFEPERFLRPSKVHPAANRTFGGGSTLCPGRHLAVDEMITFTAMFLSKFDVTFPDGADSLPKEDDTNMLSVKKPNSDVLVGIRTRPETKHQKWCFSTGTLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG06</accession>
    <name>A0AAD8UG06_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_754563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000083">
        <property type="protein sequence ID" value="KAK1721456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362252.1">
        <property type="nucleotide sequence ID" value="XM_060514487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG06"/>
    <dbReference type="GeneID" id="85398385"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF146">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="485" mass="53562" checksum="DD7A0AED461038FE" modified="2024-05-29" version="1">MDELVDWAKSHGAVLHPSVEVYNDTNTGNSFRVSRDGAGVNPGDTVVTCPLALTLSYLNATTTPNSGFHHDSTSSQAFPTSFLESVPPHVISRFFLIKQYLQGPSSFWHPYIRILPQPTNLAAWALPPLWPTDDIELLEDTNAHVAIAEIKTRLKAEHKHALAAFGDDPARHDYTRLLYNWAYCIFTSRSFRPSLVIPAHRQHTLLLPEGCAIDDFSLLMPLFDVGNHSPTARVAWETSDDAVKDEEATVGLRTLDTYAPGAQVFNNYGTTKTNAELMLAYGFTIPESEILHNDYVHVQKRGGGAKAAAEKGDDGAGAASGNNKPKDYLISLRPVSDPSSVAARSGQLLSDVDGDAILPPFRHVQDIMVWELVLAQTTAEQRDEMIPVPEGGGGDDDGSKADLERLRMILTGRVPAATQPLLFQTIGIIQHKVLQELERLDQSEFEMEEAESTRNQIMAYRYRRQCRKVLESVLESMEMPDEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG67</accession>
    <name>A0AAD8UG67_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_755508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361185.1">
        <property type="nucleotide sequence ID" value="XM_060514624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG67"/>
    <dbReference type="GeneID" id="85398522"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1718185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="353" mass="39097" checksum="1E90EF0808A038F3" modified="2024-05-29" version="1">MIADRASVPRSNSGSGSSRSDSSSPVPAAAIAADDGASDGDGYHDASDDSSNASTSLASTIRDYNFENRRRYHKFKEGRYMLPNDDEEQDREDMKHAMLVHVCEGALHNAPLKSPQKILDIGTGTGIWAMDMGDEYPEADITGLDLSPIQPVYVPPNVHFIVDDVEADWLYPDDSIDYIHVRNMAPALKDWPRLLSQAYKALKPGGWIEVQDMVWAFACDDGTVGPDYAPRKTMDLLKEALDKFGVDIDVADKFADRIESAGFVNQIHDVKKVPVGTWPKEHHLKSIGSYCAAVNYDSLGAVTNVPFTKGLGWTDLEIEVFLIQVRKDLLDNSNHAYHYYHSYSGQKPLEAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGH6</accession>
    <name>A0AAD8UGH6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide exchange factor Vps9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_678620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361244.1">
        <property type="nucleotide sequence ID" value="XM_060511180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGH6"/>
    <dbReference type="GeneID" id="85395079"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14369">
        <property type="entry name" value="CUE_VPS9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041545">
        <property type="entry name" value="DUF5601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041804">
        <property type="entry name" value="Vps9_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="453"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="764"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="807" mass="88368" checksum="5EED0732FEF6BC0F" modified="2024-05-29" version="1">MSSIDPTDHSSGLSGAPQNDTAAAPVTSAETAGSKAETELLKLDNHVEDKQPVLSAKAAGKQQATDDLIDFGEDTPVTTTTTKDDPNVDDKPSKDSPKTVFKPAPVTIPEPMTSSIATLKPTSPLPAETATQFLTIESTTYVDPTPPTPRTSQPPSRTPSNAKRRPTSASPTRSDAGYDERRYASEDEQENGSRSEIQSIMEQFTGDGGGPGAEEVMSPRLEIASPMLGSPGIQHPPRKSSLEPLVPSLSHQVQELQGLRIQSASPASMFSKERAPDDQGPPVPPKDGPPATPARSHDDRQMSIDSQMSPGMPVHRPPPPEPEPEPALPFDFHRFLEQLRNKKADPVARYLKSFLSEFGKRQWMVHEQVKIISDFLAFIANKMAQCEVWRDVSDAEFDNAREGMEKLVMNRLYTQTFSPAIPPPQPIPGAKPKRRGGERPMGPGRRGQHQEDVERDDILTQKINIYAWLREDHLDIPPAGDSGKRFLKLAQQEILKIKSYRAPRDKIICVLNCCKVIFGLLKHSKSDSSADSFMPLLIYVVLQANPEHLVSNVQYILRFRNQEKLGGEAGYYLSSLMGAIQFIENMDRTTLTITDEEFEKNVEAAVSAIAEKHRLDSPAVAQEPVFSEKSSTEYQTGESSTRPSLDIMGESSTPRRSTSSNEGGKDSDDQAPITGLLRSIQKPLSTIGRMFSDEPSPAPPVPSNASRPTSRPRESSERLSPRPSAEISPDGRPPSSRHHLSAEEAAARQASAEVAEAQRLSRVEHNNVVETLQGMFPDLDREIISDVVHQKQGRVGQAVDACLALST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UGV6</accession>
    <name>A0AAD8UGV6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_580348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363721.1">
        <property type="nucleotide sequence ID" value="XM_060505343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UGV6"/>
    <dbReference type="GeneID" id="85389242"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07739">
        <property type="entry name" value="metallo-hydrolase-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050855">
        <property type="entry name" value="NDM-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42951:SF14">
        <property type="entry name" value="METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041989145" evidence="1">
        <location>
            <begin position="21"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="329" mass="35768" checksum="033B5DBE8D285BE9" modified="2024-05-29" version="1">MFSKIITAVTLSGVFGKAAASCTCDLKVESYISPGFSLDVVSSLIIGSQAAVMIDLPLAVADAEILAQWVKNTTDKPLLAAFTTHNHPDHYLSGKAFLQHFPEAKHYATPETVHGIQNEAINKTEFWSAAYGPGVIAPVPAIPTAYNFSFFTLPGDEKCPIEILKNIGGDTIDLSSFWIPSIKTLIAGDVVYGHQMHAWLADLLTPALTESWLTTLDFITGLRPSLVIPGHALSSDTFSAVADVDHTRDYVSFFQKNIEAKGADFYTPQEISTMIEAAFPGLTNLTSSTTSATLLNITSENFGRAGQRQVHYFDLTVYNDTDVLDGWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH12</accession>
    <name>A0AAD8UH12_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carnitinyl-CoA dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_631834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000094">
        <property type="protein sequence ID" value="KAK1719521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361605.1">
        <property type="nucleotide sequence ID" value="XM_060508925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH12"/>
    <dbReference type="GeneID" id="85392824"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="283" mass="31529" checksum="54A48001F7B752D9" modified="2024-05-29" version="1">MATPRTKKPVPPWIENPYPHIEHSLIAFPRKHILLVTINRPEHMNCLPVEATIELGALWKWYDAEPELRCAVFTGAGTKAFCAGMDLKQRLDIIKTNDVAFDYPPGQFAGMSNRTGRKPIIVACNGHAHGGGFEAILNADVIFASPNATFRLPEVLRGVSALAGALPRCMMLFGNHRTMDLILTGRTMSVEEAYNWGLVKEVVPQERLLERTLNYAGQIAALSPDSVIISRLAAREVWETGVSRATMRGQELWAEAMLRSKNATEGLAAYREKRDPKWFPSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI46</accession>
    <name>A0AAD8UI46_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_581229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363302.1">
        <property type="nucleotide sequence ID" value="XM_060505437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI46"/>
    <dbReference type="GeneID" id="85389336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF3">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="35"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="331" mass="36277" checksum="3DA9907911D084CA" modified="2024-05-29" version="1">MSLTKTTLVFAKRTIPLECDVYSSAEYPLTAPVFLYFHSGGLVSGSRECVPPWLVQVCFKNQWTLISASYRMLPQAKASGLLQDATDAYSFALRWGITNELASNRKVIVGGSSAGFFVASLTAHHLRPTPIALLSITGITTFRHPYFSSSVLLTPEPITEAQMSHHLSAPVSIGVTSANNPQVFHIEKILPDGARNTAFVLPPLPISDDGNCDEFPRGCLYDYYLYRNEFLNLVGEVDPGYEWAESERGESRAAAWPPTTVIQGDADEDVDLSVSTHMVHCLGESKVKLFLAEGQSHLYEATRFIEDDVSGMDAVRQAVSNLEADVARVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI53</accession>
    <name>A0AAD8UI53_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Cellobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Gentiobiase G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Gentiobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Probable beta-glucosidase G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">BDZ83DRAFT_752603</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="JAHMHS010000052">
        <property type="protein sequence ID" value="KAK1724356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364411.1">
        <property type="nucleotide sequence ID" value="XM_060514220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI53"/>
    <dbReference type="GeneID" id="85398118"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041991380" description="Beta-glucosidase cel3A" evidence="22">
        <location>
            <begin position="20"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="23">
        <location>
            <begin position="709"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAK1724356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="793" mass="85419" checksum="922254FBE15A1CB4" modified="2024-05-29" version="1">MLWTSLLLLLLAGAQLSLSSQVHHRSNKNGTRDRPTALALANTLISHLTLEEKVSMITGNSSAGNCIGVIAPIPRLGFKGICMLDGPSAVNRADLVSVFPSGITAAATWDREMIYRRGVAIAEEFKGKGGHVILGPSTGPMGRAALGGRNWEGFGPDPYLAGITIEHTITGMQSTGVQTCSKHYIANEQETQRSNTTVNGTVIEAISSNVDDRTVHELYLWPFANAIRAGTTSIMCSYNRFNQTYACENSHLLKELLRDELGFQGYTVSDWFATHSTADSINNGLDLEMPGAVPGNYPGAASFFGDKVFEAVASGTVSESRIDEMVRNILTPYYLLGQDAESYPSPDPSLRFVTLFQEVGPQVAKDTGFIPDGFIFTHGRDVRGDHAKLIREMGSAGTVLFKNVNQTLPLSKPKIIGVFGNDAGEMTNGFLRPSEVPEDTNTGTMIIGGGSGTGRPSYVISPLAAVRAKAAEYGAEVLYVTNNDVLAANDFRGVYPPPEICLVFQQTFASESFDRTSFELDGNSTAVINNVADFCETTVVVTHSGGVNTMPWANHTKIGAILAAHYPGQESGNSIVDLLWGDVAPSGRLPYSVPRNEEDAGPAIVNLTQPVVDPLAWQADFTEGQMIDYRHYDALDIDPLYEFGFGLTYTTFAVVDNQVEVSFIGGNSSVAAQPDAAIPIQPGGHPQLWEDLISVKASISNTGNRTAFAVPQLYVSFPGSAPEGTPKKVLRGFEKIQIEAGGSAEAEFRLMRRDVSLWNASDKIWVIPEGEFTFRVGFSSRDLPAEKAFSVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI93</accession>
    <name>A0AAD8UI93_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn 2cys6 transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_586026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000102">
        <property type="protein sequence ID" value="KAK1718160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361160.1">
        <property type="nucleotide sequence ID" value="XM_060505905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI93"/>
    <dbReference type="GeneID" id="85389804"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF46">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1718160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="50901" checksum="DBDA8CE05945CAB9" modified="2024-05-29" version="1">MGTGVPCPNPIPRKANVIVPTTAPPTTTTTTVARVSSPPCSVSRKPSIATASSVGSPPDDASSDSSTESASSPPSKILESLSPYGSTLGRLDTVERNSLSRLLHKSNFMQYFISPTFVDSMQLDMTVHLFSMFDQGKDAYIAMYSAFASSMGLETGEYDPEANLHRGAMAVEHLRSCPLPTLKRDELLPWAGLGLGIVYFSNMALGTSAAPVRRYVLSHIRHLLGTSQISSSRTHYILVYMTAVDINECLMQRELPVCGIAPPEAGHVDAYVGVCMPLLQHMYDLCRISYHLYHEVDVEEQTQALDEVEQEIEAWQPVIPPDFTNRFTTTEVIHMLAQSRIYKTAAMLYIHRLRYKFGEKDDMASAMAKSIISDLQMTLTVSQDKQRCVSFPYTLAAIEAKDAAERETTMDAIKSLIDSGNSKYRSSMETFLKAVWDIRDNQPGASWLDFMQTLPPISVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJG5</accession>
    <name>A0AAD8UJG5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_458220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361655.1">
        <property type="nucleotide sequence ID" value="XM_060503215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJG5"/>
    <dbReference type="GeneID" id="85387114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1720144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="59" mass="6925" checksum="3527B87ED0C0D7B0" modified="2024-05-29" version="1">MKFGSSDHLVSVSDEEHCLGIQGSMIEQFTLLHIFCEPLLHTISRLLRFKYFPQYCYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJP6</accession>
    <name>A0AAD8UJP6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PSI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_652593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000057">
        <property type="protein sequence ID" value="KAK1724027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364082.1">
        <property type="nucleotide sequence ID" value="XM_060510540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJP6"/>
    <dbReference type="GeneID" id="85394439"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1724027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="59648" checksum="FACC1B97E6E767B3" modified="2024-05-29" version="1">MGLNRFKTKLRCQVWLREVSSHEGREALLYSPLPLFPKKSAAVRTGECESDTYFSKLWQLYFAGRLCGHFNPLDKDKTRWEKGERCESSHFAERSPWGPVEKEVEAKPKVQTSPSRRCNFVEEGPLLRERHPRRFSADAFLVADLQVASRLSRSRHSQPPSCFLLSEVSFNRADFSITAVCGQSRQLMTASLAASILQDWPLSSLRSKPQDQDIDVPVGATVKRRYLHSSQCPVAALFRGRCRRVTAACAARPDLYKMDKLSAQELWQLKHNFSSARESSEEHFFRCWNHQDCKVCLAEDECSWCPMTSACVPNAYAIPLLAPAYDENICPHWAERWELRTKPLGCQVSTITSLTSIVSIVSTFIVVLLVALIVLGVRWGRRRTNATRCWVKRKAREMARSEKQELLEGFTPAVPMTTRWNQITDTSAATDGTLHPELTGGMMATSSPDRIIGPSSSSGPGMSTYSKLTVTKHDSKNLSLNPPCLSSSASNSLFKGRGAGNTSYCLDVKEPALAKNKTLKWSLGGLGAAAMFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJW0</accession>
    <name>A0AAD8UJW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_620256</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365311.1">
        <property type="nucleotide sequence ID" value="XM_060508182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJW0"/>
    <dbReference type="GeneID" id="85392081"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1725256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="591" mass="65521" checksum="CDA39A739B47AC99" modified="2024-05-29" version="1">MKDPVQRTASPYTDPKVKGPKSQILAEGTQADLRKMIASNVNKTPLHPGGVAPHQEHTELEEELHETAHIDYDRVAIIPNPSVPALYEDALVYETGSAITSSGALTAYSGKKTGRSPLDKRIVEEDSSKNDIWWGPVNKPMSPEVWKINRERAIDYLNTRNRIYVVDGYAGWDEKYRIRVRVICARAYHALFMRNMLIRPPREELEHFHPDYTIYNAGSFPANRYTEGMTSGTSVAINFAEKEMVILGTEYAGEMKKGVFTVLFYEMPIKHNVLTLHSSANEGKNGDVTLFFGLSGTGKTTLSADPQRALIGDDEHCWSDRGVFNIEGGCYAKTIGLSAEKEPDIFGAIRFGSVLENVVFDPETRAVDYDDSTLTENTRCAYPIEYISNAKIPCLSESHPTNIILLTCDARGVLPPISKLDRAQTMFHFISGYTSKMAGTEDGVTEPQATFSSCFAQPFLALHPMRYAKMLADKIEHHNANAWLLNTGWVGAGAAQGGKRCPLKYTRAILDAIHSGELAKVEYETYDVFNLQVPKTCPGVPDELLNPKAAWTAGNDSFNTEVKKLGTLFNENFKKYASEATEEVVKAGPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK52</accession>
    <name>A0AAD8UK52_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_651424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000042">
        <property type="protein sequence ID" value="KAK1725406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365461.1">
        <property type="nucleotide sequence ID" value="XM_060510453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK52"/>
    <dbReference type="GeneID" id="85394352"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1725406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="147" mass="16181" checksum="1A58AA4237366477" modified="2024-05-29" version="1">MAVCRLWDRIVLDGLGGAMEQQKNALSNERRWDAPHVLPKMMCVCLGKTLGVFQGLVLVPGAGCWVLGGAWWDSWTGIVEGTRGSGFGPPPRSAIRELRPRLTSRRHLGSLVPVTGQWAQLAQRGPTLFRWCRGSGCYRAQCTYLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKJ8</accession>
    <name>A0AAD8UKJ8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_753608</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000067">
        <property type="protein sequence ID" value="KAK1723248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363303.1">
        <property type="nucleotide sequence ID" value="XM_060514369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKJ8"/>
    <dbReference type="GeneID" id="85398267"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000036">
        <property type="entry name" value="Putative sulfate transporter YPR003C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="568"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="625"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1723248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="770" mass="84453" checksum="2C6EE31C9E606D80" modified="2024-05-29" version="1">MGSPIQSPSSLGGESEYLSTREDATPLATPLPNDNETRDPPRAGSSLHRPNTFPPSESTSLLQNVLIDHPPANSYPNGTFSPRPASPAGSMDPEFDRASSSASEIPILDPVLTAITGDDHWRKRFVRKIKSRKMHSSRTLAEQAGFKDTVWMYLSYYIPLLTWLPQYQWSYLKGDLVAALTLASLYLPMALSLADNLAHVPPINGLYAFVFNPFVYAVFGSAPQMVVGPEAAGSLLVGSVVRGSIDHDKSDEYNAEVQAKICGVVAGMAGATVFLAGLARLGFLDSVLSKPFLRGFISAIGFVIAVDQSIPELGLAKYAAEMGVGHGSSMDKLEFIFSSFDHVHKLTFIVAGVSFVIMMTMRELKKHMVPKYPGVAYIPDRFFVVVIAAVLSWHFDWESKGVEILGPVKAASGHLFQFRWPFQTSHMEHVREAMGTSFLIALLGFFESSVAAKSLSSSDSPHGIQLSPNRELVALGAANIVGACFMSLPAFGGYGRSKLNKQTGGKTPMSSIFLSLITLLAVFFLLPYFYYLPKPVLSSMITVVAWSLLEEAPHDIAFFFKIRGWTELGLMLIIFVSTIFYSLTLGMAIGVGLSLLQVIKHSTRPRIQILGRIPGTQRFENAELNPDRLEFVEGCLIVKIPEPLTFANTGELKARLRRLELYGTSMAHPALPRLRGEQHNKNVIFDIHGVTSLDGSGTQVLLEIVSGYRERGVRVFFSRGPTNPRHHIWRLLRQAGIIDLVGGESHFVTDVQEALKLTEYETSISEVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKT1</accession>
    <name>A0AAD8UKT1_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_272092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366177.1">
        <property type="nucleotide sequence ID" value="XM_060502063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKT1"/>
    <dbReference type="GeneID" id="85385962"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1726122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="385" mass="43760" checksum="85223E466CF66A9E" modified="2024-05-29" version="1">MSTSADIPNKTRLSHQPSKIRAVLSLPPQWLHMYEEFITKNSSQVSQIESALRSLTYIIPGRFRDAEIASETVHSSVQLLSLYHDTLLMRALSRIPMARLPSPHARYTKYWTQRSPMYRRIAMLLQMVTYTQLLCEMAAKRRGGERSRWRVVVLLEAIKAICRLLLLRVTRSRPLVSPVLPEREPIPEETEAESDAALKDILEEPTNGHAPEDSEEAQKPHEKDWTMPRTGMSLPSLPNAGDISGYLLGKVLTAEDIKPAAKLLNQLQGSAQAAEVLHILAPLVYAIALSKSKNKKSWTPWLVGLSVEYAARQLRDRGFRTTPLERDEWSKRGWAMGWWTMRGAFYENIMKGVVGGVRSRVPNLVGGILEDYEYLWENYYFSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UL30</accession>
    <name>A0AAD8UL30_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="9">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_309896</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the carbohydrate esterase 1 (CE1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JAHMHS010000043">
        <property type="protein sequence ID" value="KAK1725283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365338.1">
        <property type="nucleotide sequence ID" value="XM_060502304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UL30"/>
    <dbReference type="GeneID" id="85386203"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010126">
        <property type="entry name" value="Esterase_phb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050955">
        <property type="entry name" value="Plant_Biomass_Hydrol_Est"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01840">
        <property type="entry name" value="esterase_phb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037:SF3">
        <property type="entry name" value="FERULOYL ESTERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43037">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10503">
        <property type="entry name" value="Esterase_PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="2 9" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041771621" description="Carboxylic ester hydrolase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1725283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="292" mass="30593" checksum="FEE6E04D74087E35" modified="2024-05-29" version="1">MHPLTLFVAALPLATQANAALQRVTNFGSNPTGLTMDISVPPNLSASPAIVLALHGCGGSGAAYSRQAEYIPLSDTKGTFVVIYPSSSRDFNCWDVATTASLTRDGGGDSTGLANMIRYTIGQYGADPKRVFVTGSSSGCMMTNVLTATYPDLFAATSCYSGVAAGCLAGSPGSSPISADPTCANGLVVKTGEQWAAQVRAMYPGYNGSYPRVQTFHGTADSLVKYPNLAEQLKEWSTIHGVSFAKNNTNTPISGYTQMIYGDGTKLVGYSAQGVGHTVPVQEDQDLKWFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULP3</accession>
    <name>A0AAD8ULP3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_651071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365698.1">
        <property type="nucleotide sequence ID" value="XM_060510424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULP3"/>
    <dbReference type="GeneID" id="85394323"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="446" mass="48234" checksum="B78D2F97A964A072" modified="2024-05-29" version="1">MCCGDDEKGDRCFFRVSSLKFHGGDLIVTASGTPSHPDDIIPIGETEWGRWIPRGHHPQPSTASEPTFTWGSAPVATSGSAIPDAGSASFEGSGPPSTTRSPSIVLVTAGLPGTPGNPLSNSSSAGNSSSLQASRNCDAPVDTKYGLPTACLGEYFGEDLDDDLGYNDLSAESIRFVQKIAPQFIQESILEDFKYAIDPEDTFWKQRWHLHGRSFWSFLDVIACAQITYKEEFYNDLINVDLPGLSYGVVTIGPRINVESRVEVEAAAKGKLLVGAEMGHQGNGNLYADLTGGPDNELCSELWAHQNDALIYDGAQRLMHYYGTTMAKLGVSRLRVEAELHGPTDSVVVAWASYYGGPGPEEYYFVAVDPLGEVFYPAVCDYVDGQSPKLFLVRDPVEGIETLESPDLMYTVTGGRVSDCFALVLMQGAHEAKSYLNLSNSLNSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULU0</accession>
    <name>A0AAD8ULU0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_576022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Preautophagosomal structure membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Vacuole membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="4">During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ATG11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365773.1">
        <property type="nucleotide sequence ID" value="XM_060504878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULU0"/>
    <dbReference type="GeneID" id="85388777"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903599">
        <property type="term" value="P:positive regulation of autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040040">
        <property type="entry name" value="ATG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019460">
        <property type="entry name" value="Atg11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13222:SF1">
        <property type="entry name" value="RB1-INDUCIBLE COILED-COIL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10377">
        <property type="entry name" value="ATG11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Autophagy-related protein 11 C-terminal" evidence="7">
        <location>
            <begin position="30"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="327" mass="36027" checksum="93FC738E7F7F7C6B" modified="2024-05-29" version="1">MNSSDADAETEKYEAFMTRLGTFDMDLFAETVYKRVKDVEHLARKLQRDARAYREKAHTLQRDSHEKIAFKHFKEGDLALFLPTRNQTAGAWAAFNVGFPHYFLRETDAHRLRSREWLVARITRVQERVVDLSKSMHKQLPDTDSVNGEEDDNPFQLSDGLRWYLIDAHEDKPGAPATPGLGKSTIATNNVEAMADMHTHAQTNGKDKQRANTHSIEGVSKALSKSLESRRSSSNSKRALPFAVGGGGAALLKGNALGSETNSLRAVAPDTPTETSHPEEGQLGPSMNGHEQSGQAGQASSPLVEEGQADRPRSPEVRNMIDSLVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UPD8</accession>
    <name>A0AAD8UPD8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate-binding module family 19 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000048">
        <property type="protein sequence ID" value="KAK1724764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364819.1">
        <property type="nucleotide sequence ID" value="XM_060514185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UPD8"/>
    <dbReference type="GeneID" id="85398083"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999520" description="Carbohydrate-binding module family 19 protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="58881" checksum="E51AAEA88DD4ABE3" modified="2024-05-29" version="1">MLPSLRIADVVLLLLITQTTQAGPLRRGERYFRREWNSTYSQSIAASSDSLSPSSEPSSSVAPPVTQQDQDGTTPTPIFVTLDGSSTRTAAATTQLVDQSPSTTPVESTVQTQTIPTTTSAVFLPPMDSTISLPPQLTSGFKNVSSVVPGNTASASAIISESLTVTPHLGGSPGASSSASPGTPLQSSLSLPFPVPGGETSVAESTTIAVATPSSLASTTATAASTTAPNPQSSPDTPSSLPTTTASSSLPSSTLQPQVTGTPNNQVPTIRTSTPAATATISPAAAANNVASAKTFNALFASLTEQSACTAGQIACVKGNVGICGTNSAFAVQSCGAGTSCFALPMTTTEGVIVGCYDPQVASRILGTPISGSASVPGSTFTTTTAVPAPPPASSDLGYESTVTITPTVIATYTISVTAPGAPGTTSAVQAPGFTTTVFVTQTMTPAPAPSSTAAEGEDPSTTSTSTRKTRTSTVEEETSKSGHSSTTKSTIVESSTTEPTTTKAAGSTTTKASNPSTLTGTFTDTLIVNPIPTDAPSAAADAPSPITTPKPLSMPANGAQQGVSVLTVFVTVTEKEKETVTVTVTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQM5</accession>
    <name>A0AAD8UQM5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/Beta hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_729856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366164.1">
        <property type="nucleotide sequence ID" value="XM_060512829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQM5"/>
    <dbReference type="GeneID" id="85396727"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050654">
        <property type="entry name" value="AChE-related_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918">
        <property type="entry name" value="ACETYLCHOLINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43918:SF4">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="6"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="446"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1726109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="620" mass="64622" checksum="48A1C7288C54B7A5" modified="2024-05-29" version="1">MKPNKRFTTDEDCLYVNIFAPSNATPDSKLPVMYFIQGGGFQSLSNANFNGSDLARFGNMLVVQVNYRVGPYGFLQSKEVEAGASMNNGLKDQIQGLKWLKQHAAAFGGNPDQMVAVGDSAGATSVAMLLAAFGDNDPGLIKGAIMESVSVATVRTLEQGQEQYNCLTNATGCNKQAESLACLRSLNATALQTEDCQFNPNLDGDLVKAPTLQRFAEGKYLKVPTIAGTCTDEGTKNVPQKTDTVEEAFKNMNDQATQSLSNASLALLKETYLDKPQPVFPKSGKLWRQLATAHGDYRAHCITKIFQDAMARDGVATFNYRYGPLDDEQEAQGFGAYHTVELNGVFGPNNTDGAPPKSYSTTNAPIVPLTQAYWASFVRSLDPNAAKIQAGMPQWAAWTVDGKQRLLFQNNTGTMEGMPAAQQDNCAMLAPMIPFIETPATDAQKASVNLQKVSSGAAPPASQPAKAPAAGSGAGMNMGESMSGKQMEMESEHGNKRNGTKHGGGEGGGKGGGKDKDKGKGMGHKNGTSPDAPKHGGGEGGGKGGGKGGGKGGHKNETMPKPGGGGGKGGGRGGMGGRNGTNSTPPTAPPRVGSASSMGYGITGVLSATVVVCLGQFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UQW0</accession>
    <name>A0AAD8UQW0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphoglucomutase</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Glucose phosphomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BDZ83DRAFT_619006</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate. Key enzyme in hexose metabolism. The reverse reaction is an essential step for biosynthesis because glucose 1-phosphate is the starting point for the synthesis of UDP-glucose, which acts as a precursor for the synthesis of oligosaccharides and trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:68748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:68752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000039">
        <property type="protein sequence ID" value="KAK1725711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365766.1">
        <property type="nucleotide sequence ID" value="XM_060508098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UQW0"/>
    <dbReference type="GeneID" id="85391997"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03085">
        <property type="entry name" value="PGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000005">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000006">
        <property type="entry name" value="Phosphoglucomutase PgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="17">
        <location>
            <begin position="14"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="18">
        <location>
            <begin position="185"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="296"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00056382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAK1725711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="553" mass="59897" checksum="D43CE9CC98DF923C" modified="2024-05-29" version="1">MDVQTVEFKPFQDQKPGTSGLRKKVTVFQQAHYSEAFVTSILLSIPEGVEGSFLVIGGDGRFWNPEVVQLIAKIGAAYGVKKLLIGQDGILSTPAASHVIRKRKATGGILLTASHNPGGPKNDFGIKYNLANGGPAPESVTNKIYEASKTLTSYKIANIPDVDISTIGTKTYGSLEVEVVDSTVDYIEMLKDIFDFDLIKKFFQSNPDFKVLFDGLHGVTGPYGTAIFEKELGLKGATQNCVPSPDFNGGHPDPNLTYAHSLVEVVDKNNIPFGAASDGDGDRNMIYGANAFVSPGDSLAIIAHHANLIPYFKKQGVYGLARSMPTSGAVDLVAKKQGLNCYEVPTGWKFFCALFDADKLSICGEESFGTGSNHIREKDGLWAVVAWLNIIAGIGEQNPGVTPSIKKIQQDFWTEYGRTFFTRYDYEDVDSEGANKVVGVLKDLVADSNFIGSKVGDRTVTGAGNFSYTDLDGSVSSNQGLYATFSSGSRIIVRLSGTGSSGATIRLYLEQHSSDPKTYDLDAQDFLKPEIQMATELLKFKEFIGRDEPDVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8US91</accession>
    <name>A0AAD8US91_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_608480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368623.1">
        <property type="nucleotide sequence ID" value="XM_060507483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8US91"/>
    <dbReference type="GeneID" id="85391382"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041978169" description="Secreted protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="8150" checksum="7699EE1E259C1568" modified="2024-05-29" version="1">MLPNTDVLMDCISLLTTVLSWMAKARSSDWYYYCLLTTISSSIQQISQAICHVFHLDRPLFRAFKSYRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UTN2</accession>
    <name>A0AAD8UTN2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_614370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000028">
        <property type="protein sequence ID" value="KAK1726924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366979.1">
        <property type="nucleotide sequence ID" value="XM_060507829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UTN2"/>
    <dbReference type="GeneID" id="85391728"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="26500" checksum="C43839C98B3C349D" modified="2024-05-29" version="1">MSCISSREGVCRIISRAPAYEKNRENGEETRKKGFFSVLTRRWSIRTTPRTLSDLAVSVHPDEGAQEFKGVERAYDLSDRPVNHESVNQIKAGKQKKMVFVIHQEHPLGCRKEYTRVTANKPHRGGEGGKPDVSMPSCLNSPPGIPASRLFASLFSRRLAPTLQVLPPPPSSRLERTTLPVDGSWPSSKRVGTWTTNPSIPACTALPTTREKVRRSERLRWGEKREKRKRRTAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUD3</accession>
    <name>A0AAD8UUD3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_649226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000021">
        <property type="protein sequence ID" value="KAK1727864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367919.1">
        <property type="nucleotide sequence ID" value="XM_060510253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUD3"/>
    <dbReference type="GeneID" id="85394152"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="163" mass="18160" checksum="7A3D06E3E8003786" modified="2024-05-29" version="1">MHSALIPRCLSYLLFPQSNFSQKRRQISSLRDPLCKVRIAFWELLVDLRRSFTSLGLSTRTVPSLLVSSTAPDQTRIYLGLEAASPLPPSFFGLFLTDDYGRCRLRSQKKQQQQSSSSGSSKRAHLHLTVIAPLRSFPGYFGLDDASLDPEPGKLGLPDHLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UUY7</accession>
    <name>A0AAD8UUY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_614685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000029">
        <property type="protein sequence ID" value="KAK1726775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366830.1">
        <property type="nucleotide sequence ID" value="XM_060507855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UUY7"/>
    <dbReference type="GeneID" id="85391754"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="315"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="416"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="445"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1726775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="621" mass="59911" checksum="0BC7AF747BD1BA0E" modified="2024-05-29" version="1">MLPAPCGMGWPCYHCKGGWYCAPDNNNMAPAAANDPPVVVIKTVTAFVAPQPTGVGNGGTGDSGNNNASGDGGNGNGGNGDNGNGTPGNGNSGAGNGGSSAASTPCTTASNGQYTGPPGNGAGSAPNPSPDNSSSGNGNGNGNGNGNGNGNNDPGNGNAGKGNPGNPASTPCTTTGGQPTSQSGSDGGSGDGSGISGPANVPEPPAASPTLSPSNRNPPASPGQPLSPASPSPNGNPPAGYGSSPANPANGNSNNGSGNGSGSGAPSDNGAPGNTGPSSPEAGSNAGAGSGNAGAESDNGSPDNRGPKPAPEVTGWEYLGCFKDYAVRTLDGDPSIYFTGSMSNEKCIAHCGSMGFQLAGTEYGKECWCGTAFQLAVRIPEEMCNEVCDGKSNDICGGDWAVTVYSKTGQALSLPSDDDVANGAGGGNGNSGSGTGNNGGAGNPPSAPQNPAPGPPAGPPAAPPASPPQTPGQGQPPPPPAGNPQDSSTPPTSPNPAPQPQIDIASLIQSIINALPKSSPDGAYGSSLGARDSGAPGSSGLALPVNSAVPNNSAGGSPMMGPGLINPMEGLSRYGGKTREMESRNMKRSSIIGRRAVAKFDGIICDREDECDDGCLTKAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UVN6</accession>
    <name>A0AAD8UVN6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_648597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000016">
        <property type="protein sequence ID" value="KAK1728648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368703.1">
        <property type="nucleotide sequence ID" value="XM_060510196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UVN6"/>
    <dbReference type="GeneID" id="85394095"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1728648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="152" mass="17153" checksum="E3DF7F52A3FD7D39" modified="2024-05-29" version="1">MNAAGLLQSPQWFLTSTSSSLISDSSLRLTSRSNTPKTSRFHTNYLSPHTSLHTTAKMFVFAVSRSQLLSADRLEELRYKAKMQYYQAHVLDLAFCDVDLEDHINDFIEGYYKQQTCATTSSSSVSLASDEASTKSKSRLRHLLHRITGKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UXL4</accession>
    <name>A0AAD8UXL4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_570950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368420.1">
        <property type="nucleotide sequence ID" value="XM_060504357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UXL4"/>
    <dbReference type="GeneID" id="85388256"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="50"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1728365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="395" mass="43371" checksum="0C001C801A428EB8" modified="2024-05-29" version="1">MPVVNGVVTVLSPPEGYVVNFDNPQRQAVPEAYYVAGFGTLLSLLLMAQRLYTKAFLIGRLQWDDVFLLLAWFTSIATIGLCVHMFAYGSGGVHGWEISVEKYNIYMMDVFLAAAIYTLCGSFAKVSLLIFYFRLSPQRWFKRAVWISLAIIAGYSIGIFFALVFACDPIAMSWDVTVTEGTCINRPSLYIATAAANIISDLILFALPIPIVVKLQIPRRQKVGLFFIFAVGSLTVVTSIVRVSLLPAMLTSMDQSWVISWASLWIIVEANLVVICASLPTLRKFFRHVAPKIIGESTYGKGTKTVGGTGSKPMSRMTIGGTNGTRNRAEYSQFDRDNNGEAFVMASMGSNEPVTIATGHSEGDPAEDDSSEKAIIRGNNIVQTKTITVEYSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7U8</accession>
    <name>A0AAD8X7U8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity methionine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_758562</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000240">
        <property type="protein sequence ID" value="KAK1705615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357639.1">
        <property type="nucleotide sequence ID" value="XM_060515053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7U8"/>
    <dbReference type="GeneID" id="85398951"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000025">
        <property type="entry name" value="High-affinity methionine permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1705615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="593" mass="65493" checksum="906DF270F5E40342" modified="2024-05-29" version="1">MVFSRFFPSEKSGGADSTVRADPEASDSEPSIIHDGDLAYTRVKGGNGSKPSYQEAVGAPVESDSPLEYHVNWVAIIFLNINMMVGTGVFSTPASILNRTGSIGLALMYWVIGFLMASAGFSVYLELASYFPNRSGSEVVYLEQQYPRPKHFFPVAFAVQSVILSFSSSNAVVLSRYLWRMADITPSEWQMRGVAIAAYTLAVICVLAHNRYSLWLVNFIGVLKLLTLVFISIAGLVVLGGNVKHIPDPKANFRNAFEGTTSNGNDLSNALVSIIFSYAGYYNAFNMTNEIKNPIPTLKKNGIISLLTVAILYMLCNIAYFAAVPKAEFKGASEIAAAVFFSKLFGGSKAAANVLNFLVLLSAFGNLLAVLIGSSRMIREIGRQGVLPFTNFWVSTKPFGTPLGPYMLKWTMTFIMIVAPPAGDAFSFVVDLASYPSAIFNFAMTFGVFVLRRRRQRSGISRSEFRAWDFVVLFFLAIQVFVLAMPWWPPKGGPYAGSVSFWYATYCVVGIGIILLCILYYVFWMYVLPRWLGYEIRTEIVEVDSNGANTHRLVRVPKAEVAAWDEVHDEAGNLRRRHVTTELDSGNSNEKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X7Y9</accession>
    <name>A0AAD8X7Y9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_198851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000230">
        <property type="protein sequence ID" value="KAK1706126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357774.1">
        <property type="nucleotide sequence ID" value="XM_060501646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X7Y9"/>
    <dbReference type="GeneID" id="85385545"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1706126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="246" mass="26698" checksum="895E1348D2A5B68D" modified="2024-05-29" version="1">MLEAKEGENTVQIFRDTGDGKPKLLYTDSDVAAMEKSIEEGGFDNCKICIEGGGVKIRRQKGILRKFCCFLSPQTLEAPEPVWNDQTGLATGLGTSEAIPLANRVVATLSETAALTADEKTLITTMSQGFANWYTKAQSVSANVDEISAVLLEARKKTADWGKIATATSKAYGLSDQEKWALKTWIQWYMINPEFNNALSKLPSATGLVVRSTDLDAATVNMLNKLESGVISKGKAGIYEVQGQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X8U3</accession>
    <name>A0AAD8X8U3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_757989</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000194">
        <property type="protein sequence ID" value="KAK1708449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358327.1">
        <property type="nucleotide sequence ID" value="XM_060514969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X8U3"/>
    <dbReference type="GeneID" id="85398867"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10917">
        <property type="entry name" value="CE4_NodB_like_6s_7s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF6">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="510"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1708449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="713" mass="77167" checksum="580B9A8A90397FDF" modified="2024-05-29" version="1">MTSISAAGGILSFTPKSGAYYYETFPCQAMQTDLYTHVQLDIKAPVSGAAFTTELNSASSCSATTSSKTSFRVTGLTGGWQTLRIPLSSFAAGNLNAALSFVLGSFSSTQEWQLDKISFVCAQGSSATSTFTTITTVTQAPTSSVPSPTQSNNPACSALLVDDWASQSRLDFLQYNSLLLPTGDDGTMQSKVVSNHHITLTPKDTSSYFFTQVGCLDASKYGGISLRINAPAGTTFKIELTSKTTCEGEVTAYSSQTTAQLGWTFDGTEKLYSFPWSKFSGVNLSKLRSIVLEAPTRPITLGSLALYCGSTPTGWVVPMATTPTGPTQTVPAPAATVSGLVIDTFANANTNSLGFWHGGDELGLTWGSNRVTIVASAPDYAFTSLMSGGCRDLRSQSGSYLHITYSGHTKFSISLQQHNSQCNDGVAPYPETRDSLEASRYATTSSDIYIPISHFNINLQRVASVAIRGIYSTEPVVLTKIEIVPSIPSGVSIPQKLPSGTLVFACTRPNSFAFGIDDGNPKYAARLAQIISDAGIKVTFFAVGAVLENPSTGMASLYQQLKSEGHQIALHSYTHPRMEGLPDTESIDWEYNEDYRVMTNLFGERSNYFRPPYGVEGARMRQRWAAASRSDKAYLINWSVDVQDWLWAETSTPEKQVDSFKADVAKGGNLVVMHFSYNTTVEYFPEFIRQAKATGKQIMRIDQCMEDPNAPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8X9J3</accession>
    <name>A0AAD8X9J3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thiol-specific monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_734815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000143">
        <property type="protein sequence ID" value="KAK1712913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359529.1">
        <property type="nucleotide sequence ID" value="XM_060512956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8X9J3"/>
    <dbReference type="GeneID" id="85396854"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="461"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1712913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="59360" checksum="E91ADA1384358FE0" modified="2024-05-29" version="1">MGGERKIKSVAIIGAGAAGAVTAAAFKAEDYFERIQVFERRESAGGTWIYDPSPSELPPLQPGSLPPDVDPAVEIPGELPQVKPHSQRERYSQTPIYHSLTTNVPDIAMSFSDSRFAYGPFAPHWIPRQYIENYFSLHKTDSILVLNTTVEDVTKVPAKDRPEQWRLTLRKFDAARNVDVWWQEVFDAVVFANGHYSVPYVPHVKGLDEYIKKFPGRVVHSKTYRTPQPYTGKKIVTIGNSASGHDVTEELVQTVRIPVYQSRRSKSRWDGDEPPPGIAWKPIIKEFRLDGRIIFEDDSYLDDVDHIIYCTGYKPSYPFWNSQANGGRALYDYKSGKLIKTFWHTFFQDFQTLGIVGMPRVLTFRSFEYQAIALARVFSGRESVALPPVEEQERWEREREELVRKEGRKFHDIAWETGETFEWLNWLFRVAGLPTLRGKGRTPPVLSEELIWAVEHLRKYPEPGNPDDDDDEHQRKDKRAQSLGLYEEIHQQDKEGHKGKWKLAQRPKKDLLEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XA32</accession>
    <name>A0AAD8XA32_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BDZ83DRAFT_756398</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CBS 112980</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1714986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360129.1">
        <property type="nucleotide sequence ID" value="XM_060514736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XA32"/>
    <dbReference type="GeneID" id="85398634"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02173">
        <property type="entry name" value="ECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="415"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAK1714986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="451" mass="50249" checksum="9FDBFB095963A3A1" modified="2024-05-29" version="1">MVNSDPEYPPGEPAPEILEERIWIDGCFDFFHHGHAGAIVQARQLGSELYIGVHSDESILENKGPTVMTLQERLAAVDACRWVTKSVGQAPYVTQLDWISHYGCKYVVHGDDITSDADGYDCYRFVKEAGRFKVVKRTPSISTTDLVGRMLLCTKTHFIKSLENLLSGDEGQGQGAASRDEVKAEAQALTERMKLYATDETGKNPGVEVWFWAASGEAKAEATVEEKGVFSRFLPGKGPRIGQRVVYVDGGFDLFSSGHIEFLRRVVEAEEELARGEGWYTEQAVNERVSKGGDYPPAYVVAGIHSDEEINHWKGINYPIMNIYERGLCVLQCRYVDAVVFGAPFAPTKAYLTSLPWGTPDAVYHGPTAFMPLTYDPYTAPKEMGIMRAVGEHEFASVNAGTIVQRIMRSRDMYEERQRKKGIKAEGESAARGREILEEEQAAREADRARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAA8</accession>
    <name>A0AAD8XAA8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Subtilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BDZ83DRAFT_587964</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000121">
        <property type="protein sequence ID" value="KAK1715540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360339.1">
        <property type="nucleotide sequence ID" value="XM_060506089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAA8"/>
    <dbReference type="GeneID" id="85389988"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000026">
        <property type="entry name" value="proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000005">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF14">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 14" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003188" evidence="17">
        <location>
            <begin position="17"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="706"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="18">
        <location>
            <begin position="473"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="649"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="753"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="672"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="780"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAK1715540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="804" mass="88089" checksum="9EBA691139B01DB4" modified="2024-05-29" version="1">MKLSAVLLGLAALASGTSTPRNYETNDYYVLELDSSTSPGQVADRLGLRHEGTLGSLDGHHIFSARKVEHDIVKPALQERKLRKRTLGGSDVLDGVRLSQKQQLRKPWEKRVPPRSHGPANYARQDAADPKMVEQMNEVMKTLGIADPIFNEQWHLLNTVQPGHDINVAGVWKSGITGKNATVAIVDDGLDMYSDDLKPNYYAAGSYDFNDHREEPKPTLSDDKHGTRCAGEVSAAKNNVCGVGVAYDSKIAGIRILSKLISDADEAVAMTYDYQHNDIYSCSWGPPDDGRSMDAPGILIKRAMLKGIQQGRGGKGSIYVFASGNGAANDDNCNFDGYTNSIYSITVGAIDRKGQHPYYSEKCSAQLVVTYSSGSGDAIHTTDVGQNACYNGHGGTSAAAPLGAGVYALVLEARPDLTWRDMQWLAMDTAVPIDEANGEWMPTKIGKKFSHTYGYGKIDAFKMVEAAKAWKNVKPQAWYYSPWIHVNKDIPQGKDGIAVSFDVTVDALKQANLERLEHVTVTMNVNHTRRGDLSADLISPEGVTSHLSVTRKMDSAKSGYVDWTFMSVAHWGESGIGKWTVVVKDSNENEHKGTFVDWHLKLWGESIDASKATLLPMPTEEDDNDHALVATTTLPAATTTMTHAAENTATVVKPSDHPERPTKIQSGADATPTETGKPTDTQETPAATTSPSNWVSWLPSFGKAGVWVYGAIGLIAVFCSALGIWFYIRKRRNSAPRDNYEFELLNEDETEGLNGEKRTRGRELYDAFAGDDEDDDDETGAYHDNRDRSREGSGNRETDRLTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAI6</accession>
    <name>A0AAD8XAI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_588379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000126">
        <property type="protein sequence ID" value="KAK1715014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360157.1">
        <property type="nucleotide sequence ID" value="XM_060506134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAI6"/>
    <dbReference type="GeneID" id="85390033"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="841"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1715014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="931" mass="101003" checksum="4484DE2706FF9A38" modified="2024-05-29" version="1">MGRTSKFTFPVPGRKQKPPFGPIVSGPMSKAQKILGTAEINIDAPRQWDSASNSGISVCVSESTATYNPSERSRGVMRHEEEGSYAGNNRSRNNNANAQWEQESEIVPAFLTNRFAQLNTEGSQREFTTETSSLARRGSNSTITSWYDKTKMPLSISQQTSSSAMAKGLPQKANAVLDIEGQSSTNVPAPLNLKAKKRPSRLDLGPLLSRAKHNSLKGKSDSQRASSVRGNEYTNRSPSLASVTSPKSTPPPIQQRIERKLTRKSTYDSLNSTGSRPRTGSSSRRGANDISTLPNLYEHYEQMSFDSVLGHDGPLAAASTHSLNSVAHTPLRSPSTTDQQRRNFSRPPLRHDGTTSTYQPQFGPLPESTAASTGHQQTQPDRDCASSVSSRYTKTSKASKRTSQSLNGSDLMEKSVLSLSSDSEDDFFPDSVSKFTGGSRSSDAGSLAPSSLRSTHSRDAPSLGQGSRKSVKHASFAPTNTYLTIPSKSPPSKPPSVNARMSSLPSTTYRPPPAASNRSSQYSTMSTSTTDSLNNSLTNSVNSRQSRASYGVQEARVIAVLPPQESHPTPDRMMSNPPQRMLSTKSSSVHSVDQPTPPTSPTSVESFMSSGGGAAADVNNTADSRFMAVTRQEEMLLAALRMKRARMRESILAEYEDESRSSSSFHQRNSSQGTITEMDWPEPPQTLRHQTSATSNSTIKAGSRASDSRPASLVRGRSHQRSNSRHLDFPAPSSQPASGASSRTGSLRKMRPVQETTQPSESSKQERILLYLDRPVGNVNSMDFAEPSPDLSDFMDFDNVSEEDEEFTSGMSMFRNRDHHRITMGAVGNKGRGRMLMTGERVRHESSPLRPRGEDDDFGSRSASTKRAPTTEIVESDSDVEPMFGIPRPDSPVSPEGTLGLPHQGLSKKKAVRLSAVGNAGVEAGWWGDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAK1</accession>
    <name>A0AAD8XAK1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_58100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000124">
        <property type="protein sequence ID" value="KAK1715059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360202.1">
        <property type="nucleotide sequence ID" value="XM_060505409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAK1"/>
    <dbReference type="GeneID" id="85389308"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1715059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="503" mass="53695" checksum="81827E5F0FB2DD88" modified="2024-05-29" version="1">MSETSSADTLGPPAMSSRTETTALLPKPPAVKSKEPRAVRPWLAEILLLAKAAVPVILAYTLQNSLQTSSVLIVGRLSPEALATAAFSYMFAMATAWLIALGGTTALDTLASSSFTGSSNKHDLGILLQRGILVLSAFYAVVAVLWWFSEPVFRALGQEEFICVQSSAFLRCLIPGGLGYVWFEAMKKYLQAQAIYRPGTYVLLITSPMNAVLNYLFIHTFGLGLYGAPLATGISYWVSFLLLVAYAVFVRGKECWGGLELRKAIRNIGPFSKLALLGVVHVGTEWWAFEIVALAAGRLGTIPLAAQSVIMTADQIINTIPFGLGVAASARLGNLLGAQRPRDAAIAAHSAAILSVILGSVVLTVLMATKDVFGKIFNDDERVVQLVGEVMPYVALFQIADGLNGSCGGALRGMGRQWVGAVVNLVSYYGGALPAGIYLAFHGWGLAGLWVGQCVALYLVGALEWVIVGFSKWEKECQRAIDRLDDSSSDDEVESESTASGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XAX8</accession>
    <name>A0AAD8XAX8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_22405</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000105">
        <property type="protein sequence ID" value="KAK1718014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361014.1">
        <property type="nucleotide sequence ID" value="XM_060501758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XAX8"/>
    <dbReference type="GeneID" id="85385657"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF390">
        <property type="entry name" value="PROTEIN KINASE C, BRAIN ISOZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="248"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1718014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="367" mass="40303" checksum="06AB5232206E3037" modified="2024-05-29" version="1">MSMAVANQILEGIKSTRMISKNKTSTSLSDRTLRQKPTSPTSTIGSPHSGGQPYAGGSPEATEAAKLMYQQQQQQSPPGQRPMHPDRTSSSTAAAAAATAAMSGSMASQQKPQSQDYSSYGGRPGYPAQAEQPDSYNSGGPKYNPADYAQVNQQAGYGQHPPAQQQQQQRPVQQQPPQQQQPPPQQYPQPPQQQMYQQSPVSSPKLQEPPQISPIASTGGVPSSGAGRKPLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVMLAETKRSKRLYAIKVLKKEFIIENDEVESIRSEKRVFLIANRERHPFLTNLHACFQTETRVYFVMEYISGGDLMLHIQRGQFGTKRAQYVTPRPFSPRYLLTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBY6</accession>
    <name>A0AAD8XBY6_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_584942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000093">
        <property type="protein sequence ID" value="KAK1720146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361657.1">
        <property type="nucleotide sequence ID" value="XM_060505808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBY6"/>
    <dbReference type="GeneID" id="85389707"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000212">
        <property type="entry name" value="Stress response regulator/HFS transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014402">
        <property type="entry name" value="Sig_transdc_resp-reg_Skn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF361">
        <property type="entry name" value="TRANSCRIPTION FACTOR SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002595">
        <property type="entry name" value="RR_SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="361"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="328"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="501"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="565"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="518"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1720146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="605" mass="68047" checksum="8A09E8CB53FC0BBB" modified="2024-05-29" version="1">MPEPDNVAAQGGGSNSSDFVRKLYKMLEDPAYANIVRWGNEGDTFVILETDKFTNDILPKHFKHSNFSSFVRQLNKYDFHKLRRNDENNESPYGKQAWEFKHSAFRADRKDNLDNIRRKAPAQRKTQQTEDQFTTNQSINLLQETLFAQQQQVQALQEQVAEMARTNKTLVHEVHTMHKIIDAQRQSQHEMLNFMSHAEDRMRGQQRYPGQNPQMNGGAMDDQPPELRRARELLSSVTTNSGYDRELERLNGMYAQSSPPDSASSLMFQPGNAGMPPMLPEHMNMRHLVYPVGENVGIDPLSQDHFNNIPYTLNSLPMNDFQAPPVVKPEPGPATPAPAAAAPARPPSTNDKGLWGNKKPRVYLVEDDRTCSRIGSKFLTQMECIVELAENGIDAVNRCKEVPSGHFDLIFMDIVMPQMDGVSATQLIREVHPDVPVVAMTSNIRPEDISHYFNWSLNDVLAKPFTKDGMLRILRKHVPHLLKNAPPDELAVGHGAAQLHANNMTAPPMNPQVKFDSTPGQSPATTASWHSPAQMHQPSPNVTNIETGYPMANTAQMVMTPTSAQRPTFQNMPPGMQQMRVPDHIVGDDRPEKRQRLYGPQGGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XBZ8</accession>
    <name>A0AAD8XBZ8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_590955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000162">
        <property type="protein sequence ID" value="KAK1711215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359018.1">
        <property type="nucleotide sequence ID" value="XM_060506385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XBZ8"/>
    <dbReference type="GeneID" id="85390284"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07713">
        <property type="entry name" value="DUF1604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26093">
        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1711215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="719" mass="77601" checksum="852558EF97F0BC5A" modified="2024-05-29" version="1">MSRSKRSHTTYEADLHDGAAVHVAFGTPLPPLESEVRDDGAYIPVHKQEVRDEHGRRRLHGAFTGGWSAGYFNTVGSKEGWTPSTFVSSRTNRRRNEPRTSQQRPEDYMDEEDLADAAATQNIQTTDPFSALGASAHTIHHAGDFTGLARAFGDTMGLKLLRKMGWKDGQGIGPKVRRTARLGVMTSTQYAATGDTHLFAPDDINMIEFDRKQNRQGLGFTGEQKLSQLSGPGIIRTNRDQFGMEDEASNGNEVSGGLQPALSISRKTGKPSQAAPRGGLGVGILNDTGSDDEDPYDIGPRISYNRVLGGDKSRKKKKQPASLSANPSVRSKPVFVAKSSSANAYGQTRCLDGKLPLKGFALAHSTESRLTGQPAVSYRPPTVPDHWRSTKRSVGGNTTTAYISTADAAKTAQHEPKSRALLLGESTLPGKSIFDYMSVAARERLAVATGRTNLPPAKAEIPAEHARTAEQKLQDRLGSIPVLAKETAIAAMSRGSGTGGPYANNEAKQARYRLYLQDAAGFGGSAPLKPLGMTEDDYVKEIEEFYGCARLFQPMTGFMATRFTTASTGPKEGADVGSPHTAQQVPGPVGQTDPTETAAKMGMYGRMTRLTADFFPTRLLCKRFNVRPPAHSRPDSDAATSLEPHKAYCGVPANEVTPHEPLSRETNSDVDDMLSFDMTKQLSKPKADIPKLGSEAGEVLRPSNDVFKSIFGDSSDEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XCG6</accession>
    <name>A0AAD8XCG6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_437399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000084">
        <property type="protein sequence ID" value="KAK1721416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362212.1">
        <property type="nucleotide sequence ID" value="XM_060503082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XCG6"/>
    <dbReference type="GeneID" id="85386981"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1721416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="199" mass="21568" checksum="3CC7B74437F4D8D5" modified="2024-05-29" version="1">MLLGEHQSQPFYGMSIHSGLSSSPPIVLHSGPSDRFPPLASVEYHGFSSRMSITLPPAPIRTPGGGPIIELESKSDFPSWSYIFAIGVGPNCETLEHFEWRTSSGEAIAALDGRSRGWKLIRLAQSVPQNAGPGAFRGGDGKEVVAVWTDAGMSMTKLAKFAFMGSGLTGELGERWAIMAVISGLAIFERQRQRRRNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDA6</accession>
    <name>A0AAD8XDA6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_589525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359635.1">
        <property type="nucleotide sequence ID" value="XM_060506242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDA6"/>
    <dbReference type="GeneID" id="85390141"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF20">
        <property type="entry name" value="2-MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G13660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="457"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1713309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="705" mass="78646" checksum="1ADE3FAE51C46E41" modified="2024-05-29" version="1">MTELPESKVDVLIIGAGPAGLMLALWLSRLGVKTRIVDKRTAKVYSGQADGFQVRSLEILDSFGVAERVWKEANRMLEVSFWNPDENGTIQRSAKSVNTIPGLSRFTESVLHQGRIEQFFIDGIRASYPSNETPLQVERMVIPTSLEIDEAAAEDPDPEAHPVTVTLRHLTEQEATPTQMLSNLSDGIFRSNLAEDDVAGILDRSKGREARDEVVRAKYVVGCDGAHSWTRKALGKEFEMKGESTDAIWGVMDIVPITDFPDIRFRTMIQNTAGALMIIPRENRMVRLYIQLKEVSAGGGRVDRSQITPEIIFKSAQRIFSPYKLEYHYCDWWTAYQIGQRTGDHFSKLNRVFLAGDAVHTHSPKAGQGMNVSMQDSYNLGWKIGLACKNILPRDVLSTYELERKKIAKDLIAFDGKFSKLFTGAPPKDIQSETGVSEDVFQKAFHTSRMFTTGVGVNYQPTVLVAKEADADQETEDDLPNTLAKSAAKSTQSLATNCKLGQRFPSYKVIRQSDARLWELHHKLPSNGRFRLVVFGGDISQPTQRDTVNALGAWLSSYLPKLPTIALGPASDPHSGQIKFKTDAAPSIVDVVLVHSAPRGEIDLLRDVHEAYHPFDSKLGWDYDKVFSDGKTFYEEPERAYEKYGIDLGKGAVVGLRPDGYVGLVTPVGHDGAEQIQKWFDGIFQRSRDDARHRQKGHEKCEGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XDG2</accession>
    <name>A0AAD8XDG2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SCP-like extracellular protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_763442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000136">
        <property type="protein sequence ID" value="KAK1713747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359800.1">
        <property type="nucleotide sequence ID" value="XM_060515218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XDG2"/>
    <dbReference type="GeneID" id="85399116"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165068" evidence="2">
        <location>
            <begin position="24"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="36"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1713747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="30987" checksum="A50A5B02827A1304" modified="2024-05-29" version="1">MISIKTVVTGIAVGLTAVGMVHASPTITSGDENRALSMINTARSEADTPPILWDNKLKEDADTWALLLARQGYIGRAPAHQRDGAGEVVAYFSSLSEDSVQVTNPLVSAVKLWLSFKDMNNFQTTVEDYYETLSTTEQLLSDKATHIGCSTRLGKKGRAVNPLTSFTVCRVYKDVEPPAVMARQDLSPGPFQGDITFFNPGLGACGWTDNDDSMIVAISHIKMGSQSNGNPLCGNTVRIQAEGKSVDVKVTDKCMGCAVNDIDVSPVVFKALLGDLGRGRVSGVTWTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XEI9</accession>
    <name>A0AAD8XEI9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_707618</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000111">
        <property type="protein sequence ID" value="KAK1716830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360760.1">
        <property type="nucleotide sequence ID" value="XM_060511551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XEI9"/>
    <dbReference type="GeneID" id="85395449"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053175">
        <property type="entry name" value="DHMBA_Reg_Transcription_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791:SF13">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38791">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1716830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="535" mass="59660" checksum="B242FF83777A9ECA" modified="2024-05-29" version="1">MVYTGKPSGGCKLCRIRKVKCDEAKPFCMRCTKSKRHCPGYGPVVRDSSKSADKLKKMRTNSTDSNMSSANSSTKIKIGSPGYCCDKTSSLSPPRRNSSPFKIGHEEGDLIECFKNVPGGLTNPLDEQASCLFLSEFVNVPLTPTARGYYAFLPRFLGRGQISVCLSAAFKATSMAALAMRQSKGARGPALLRAQEHHVAALRAVGQAIADPEEIDSDQTLGAVLMLAFYETLMSKDSMKEYISHLKGAAKIVQVRGQKCLETDEGREMFAMTRNQCISVQNLFKESEMSGYSWLLYNEAVQRSNRATVDINLLCNQLQQGVDRIIALARDPTDETVDKMLELLEKCRKLEDEFRKLSENPNPQWKVEVAEWVFDRTDEELDTEPTFDGQVYKFFNLPMAVLHLVTWCSHLNLITTMIRASSWLASAGREGLSDYDEYGDLVQSASARVANIVSAVPYFCSWNGYGVIVSQFPCGTTKPDDPLKGEAGLIVMWPLAMALKSDYATPRQRRYLRGRLRYIADVSGISQARFFMNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF36</accession>
    <name>A0AAD8XF36_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cutinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_704011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000079">
        <property type="protein sequence ID" value="KAK1722428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362483.1">
        <property type="nucleotide sequence ID" value="XM_060511490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF36"/>
    <dbReference type="GeneID" id="85395388"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="233" mass="23920" checksum="6267D0332540E912" modified="2024-05-29" version="1">MVYSPVVALGFLGALQGRSEVYSRQTNATGCATGVHMIVARASTEQPGTGVIGAIANSIQSQVPGSDIVPVDYPALLNPYQPSQKAGVTAMTKLVQDYAKACPQTKMVLMGYSQGAHVTADVLCGTSETGFASTEPQATDVTDKIAAVVLMGDPSHVTGQPFDQGTSQKNGIFPRTKTAGCDAVSSKMASFCNSGDPFCDSGANIQVHLSYVQSDGDAATKFIMSKVGGGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XF52</accession>
    <name>A0AAD8XF52_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Formylmethionine deformylase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_582802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362543.1">
        <property type="nucleotide sequence ID" value="XM_060505587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XF52"/>
    <dbReference type="GeneID" id="85389486"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF3">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="75456" checksum="499D0D8A0ADC2424" modified="2024-05-29" version="1">MYYPPEQIRLFNKYWHPSWNMYFFLFAGIAFALGHHFFYAGLDGTEANGQIRMLRYGAALSFLSKASLGSAVILAFRQRVWMTVRRKMLTLAAVDSLFAAAEDMTAIFNIEVFRQARIAMILAIYVWCTPLVVVLTSDTLTAQPATTRQTTTCPSIRTLNFAQEETNDFRTGTKINNLFELSTSLWNTTTLNQSSEDFFDYWIGTSWQFEEISTSAILGKKPLSRTNASLDVCGMGWNCSFSIQFKGPGYKCEELASGVGSTPKKLNGAEVPFNMSMLAPVGNHTYIAHATAGEYQNPQMNDTGPAGVINTPPPYPQNLGALRVEPVLWFGIAEVDEPSDPQPMNPALPAWKTAYTPKVFGCEHRETEYEVDFNYTGLTQKTTVRKRTFFDRIVDTRYLPGVDAQDGTADNTTGTPESNYIFPQDVARYRRTMAYHSIGYQFRQYINGTIFQPNTDANTKILQTRILDQHNYLVVKDFMFQVQSLYEDILISMFSQPRLLAVVWANDTSEKTGTRLGDNHTYPCTRERTDLRYKYHARDLWAVYSVAILLAIVGVAFGLAAVREEGLVRNTRFSSIVAATRGPGLEKLPWATTPNSDHRPVAGAKVGYGLVPKDPHVGGVETYGFGLEGDVKQPQREREQRDDSGRTPTRLGSPFQRGPFNRRWSRLSGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFN9</accession>
    <name>A0AAD8XFN9_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_775252</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000035">
        <property type="protein sequence ID" value="KAK1726089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366144.1">
        <property type="nucleotide sequence ID" value="XM_060515440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFN9"/>
    <dbReference type="GeneID" id="85399338"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF16">
        <property type="entry name" value="O-METHYLTRANSFERASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="236"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="458"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1726089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="491" mass="54945" checksum="BA2815638AEDEBD4" modified="2024-05-29" version="1">MNKFKFSNWLGTNPSPTAAESTPVVASEKPAYTPSRLMELAKKIASETEKLERYMQENNLPMPTLDPNGPGDFPKLPEDIQKSRMEIIFATRELEALAHGPREDVRWKTWSYQDSLSLQLVNHFGIAKLVPIDGTITLAELQTKTTMDPVNLARVLRHVMTNRIFREPSHGVIAHTAASRLLAEDQALQDWVGYNLEDNFPASAHVLQALKAYPEATSLTRTGFNFAFDTVDKEPMFVTFGKDPPRAKRFGGAMLSLTGGEGYEVRHLVDSYDFGEIDARGGTMVDIGGSHGFVSIDLAKKWKNMKFVVQDLPKTVDSAPSPLCDDAQVAERVQLMAHDFFKVQTVKDADVYFFRWIMHNYSTPYAISILKNLVPALKPGARVVIKDHCLREAGQETPWDERIIRSMDMVMLAVLNAQERNEDEYRELFRAADERFVFKGVMRPPGCRMSIIEAVWDPETESEGDGEGGRIEADAQTDAGSADSAVVVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XFQ0</accession>
    <name>A0AAD8XFQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TfdA family taurine catabolism dioxygenase TauD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_719844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000050">
        <property type="protein sequence ID" value="KAK1724606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364661.1">
        <property type="nucleotide sequence ID" value="XM_060512216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XFQ0"/>
    <dbReference type="GeneID" id="85396114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF49">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="90"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1724606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="385" mass="42442" checksum="C6F33C60995A06BB" modified="2024-05-29" version="1">MASSAVGPVVGATTAAAGHHIHHLDRNAPVADVPVIPTGFPETVVNESAWTGPQFTKQSQYTYSLTNADLDELAAALKHFKTLGLDGDLVGRNNFPLPTLGATLDGIARDIHHGKGFAVVRGIDPQQHSVEDLTILYLGIQGYVANQRARQDKKGNMLVHIVADNTSQAKADHHRHSTSAITFHNEESGDVISWLTRNTAAAGGKCIIASAHTVYNVLAATRPDIIRTLSRSDWPFALPKFQCRPVLFHHDGKIIINFGRTPLIGNSAHPRPAHFPSLTARQIEALDAVEAIAKATQMEIQTRAGDIHFINNLAILHRREAFVNGQGASEKRHLVRMRVRNEQLGWSIPDALKREWHDAFDKPADRVWHLEPMPDAFFPLRKYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG12</accession>
    <name>A0AAD8XG12_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_618057</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365962.1">
        <property type="nucleotide sequence ID" value="XM_060508056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG12"/>
    <dbReference type="GeneID" id="85391955"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF16">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="192"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="4">
        <location>
            <begin position="468"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="693"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="718"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="789" mass="89126" checksum="FEAB98305088F1C6" modified="2024-05-29" version="1">MAEALTVIEVALCITEVVERLCKYVSAVKSAKDDVRKLTQELLALKGAMDHFHVQNERSMDNPLQEQARAMLKMTQETLDAIRKKLGTPKTSSLGRAAQSLAWPFRQGDIETYFATVERAKTWFIMVLMRDSLDTTASVLSEMQKLTALVHEDIVARKTDRMLEETADLLKWLSPVDSEDKLVSSRHDRAPGTGRWIVDKTFLEWQRSTPTDRPVFWITGRSGSGKTVLFSQLVEDLRAHPSDEASEENGNIGVGFHCCSLDDAASQAVPNVFGSILAQIGATNPSILDHVRPLRKSGNTLIPQNNLSVEQIYDVMGEALELFDVFYLMVDALNETNQESVIVKALLHLCSKHSNLRILVTCTREPAQPDPSIYVRHMSTQSIDCDIEVYVEKRLSSEHSFQSLSAKIRTKIKDKVTSEADGTFRWAKLCMDRLSTLRTGRDVRRALIDIPSTLNGFYAGILTRVPQQDRALAREALAWLCFSLRPLHLNELAEAIVLEGDEVDIDDDDRLTDPSAIIEICQDLAHVSEHYVTLAHDSIRTFLQSEWIRTSSASEYALDASACHQIIMRKCLAYLRLEPFTTGPLDKLRHVKARFAAYPLLNYATNMWPIHSERFPLSDKDEKLILDFFDTKKLAHGGAFEAWVQFVLRSADLDVIRHTEPLYYAASFNMTSVLQLILRPEYKVDVNKRGGRFSSPPLFVALWRDNVEAAMLLLRAGADPDSRDTSGQTSRRLATSRKHHEVVKLMKEMSPAGAKRAPTWNWDKESQDEWAMEDALAQVRLRSYMDEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG47</accession>
    <name>A0AAD8XG47_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_575293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1725997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366052.1">
        <property type="nucleotide sequence ID" value="XM_060504794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG47"/>
    <dbReference type="GeneID" id="85388693"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000469">
        <property type="entry name" value="Serine/threonine-protein kinase 32B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1725997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="445" mass="49282" checksum="7EF3AB38FB8D6E59" modified="2024-05-29" version="1" fragment="single">YLVVDLMSGGDLRFHISRKTFTEDAVRFWIAELGCALRYIHSQNIIHRDVKPDNVLLDADGHVHLTDFNVASDIIPGKVLSSKSGTLAYLAPEVYAGKGYDVRADWWSLGVLFYECIYNKRPFDGNSESTLSQQIQLANPKYPITSPPVSLPCLYAIRDALDSNRDQRMGATWESFTKHEFFMMIDFEALERKEIEPVFVPAADKTNFDATYDLEELLLEEAPLEARARRQKPRERLKEDASDKEIREDELYRMIENDFRPFDYTLAAYKKITGQGEEGGYVNGDMVNMNQPQALTTDEATPAAMATNGGRPMPPPGPLRKSSSLERRPGSSQSGVPRRPVSKPPPIPHYPSEYSNQRAAPPAAGKRVTSPTGGMQVTLDGGGSWSDLARQDATLPTDANAISEGKSESSSGVFGFLRGKKGRGHSPKPKERGVLGKEGARQVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XG90</accession>
    <name>A0AAD8XG90_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_386558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000062">
        <property type="protein sequence ID" value="KAK1723673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363728.1">
        <property type="nucleotide sequence ID" value="XM_060502747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XG90"/>
    <dbReference type="GeneID" id="85386646"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="251"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="647" mass="74208" checksum="CFF994355BC0B468" modified="2024-05-29" version="1">MANQNGIPGGATPSIQINDGPQYGVDDLRATDSAVTSWITPVLPRLESNTSDIDDAQEHIEARLWDNAIRPPFALHSDPVFWPSKLIEHLFDREAVLSVVVHLYRRNALPAAHNAGSLDSICQEWTNRIFGIGGRTTRYRLVFAILVLMQKASCIQSFINERLDDSCLPLRLDQIKAYQGQRSRQSHRPFGRWTPLLVDNFYSLQCRLFVQFIAKSPYKGEVSHYNFDAAHVLPWVMISQPVSITAPIGADESTSMSLSGGFGEVKQIVIHGWQHNFHRTLHEISAAPGCFALKKLYIPNKEEFEQEVKHLKRFGGRHPHIVTLLATFTRHSSGGIEYLLLFPWAECDLLEFWRRNTYIQRDYQLYLWTVDQICGIADALSYIHDPNDMDHLDAKGNRLYGRHGDIKPENVLWFKSRGLGNLVLSDLGLTRTHRQESRSNRPGAEIPVSPNYRPPECDIEGTEGRISRSFDIWTLGCLILEFMVWFLDGWEGYESFKQKRMSPYINSHDTPIYFNIVRVSDDNYAFNIKKSVTDEFDRLRRHKRCSQFISDLLSLVQTRMLIVQSMDQKRIASSDLCRELVVLQGNCFRREYYCAPPVSSMATIERPWPVEARLNKVAKRHIAAIDIRHFDAIIMDYEGPTRSAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGB1</accession>
    <name>A0AAD8XGB1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_314226</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365231.1">
        <property type="nucleotide sequence ID" value="XM_060502328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGB1"/>
    <dbReference type="GeneID" id="85386227"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1725176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="202" mass="22996" checksum="F5B1356B890F7976" modified="2024-05-29" version="1">MSSFEPVVVIDGKGHLLGRLASIVAKQLLNGQKIVVVRTEALNISGEFFRAKLKYHAYLRKMTRYNPTRGGPFHFRAPSRIFYKTVRGMIPHKTARGAAALERLKVFEGVPPPYDKQKKMVVPQALRVLRLQPGRKFCTVGRLSHEVGWKYQDVVARLEERRKAKGAAYYERKKVAQRQLTDAKKNAKVDQKTAQALEAFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGD4</accession>
    <name>A0AAD8XGD4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Modin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_417448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000078">
        <property type="protein sequence ID" value="KAK1722490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362545.1">
        <property type="nucleotide sequence ID" value="XM_060502960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGD4"/>
    <dbReference type="GeneID" id="85386859"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="693" mass="79066" checksum="408A9AD0046E4F4E" modified="2024-05-29" version="1">MAMEGMSEAQFNQTLQQINDNINDDDKELFVAIVALVISIVALLASLLQVAQQYFASAAGYSSCGSKVIGKWSESKQRKIKFTEFRFEVLFEAPVIFLCPPTNKKGPVKDEPIIFIDGSEKSLLDSRSELQDQKDVSDKELAKQSVHTADNERASWVALLSALQKMEHESREWQERQYTEKVYQKPPKGSDQLESQENVTSVLKEVSDKYTLTVAIQKKRRSWDTMPTNVKKPYATTTWCHMVEMLAMLGVYWVEFNRTNDRYRAEGNGYTITGEKVSDLGIMFTFQVYGRSRFENNRVIPVDETKELCFGFLPTIYRATSDNRRLKFPNDEPRDLSTLNFASNHEIAETLVLIGCNTNTVNYFSTTSTARVGHLFPVAFEIVGMLGRTLHIEKSAFRLLPNPTHYRWDTKNFSLTKLLEAYTMQMNKLKSDQPTPSLVGRAIRRNIRKINGLIKTHTAAPGNWLSLPLMDALHEALDDTDEILTARAKVSRPTAPPRVDSMMTAKPSVFEGNPEGAVESARREMVQDVLRSHIQEVLGGFNEKPEKTTPKATGNAATMENRVRSQLRFEDIDAAPPELKQEKLMEVYFRLVRRKVIEVSRESSDRREQPTVGFGGLKKRNQTNFSTRTVETIDDEEPILLHELGEEHVTHEDIWCTLVFRMICWLMLHDFHKKDVQVSKSELLGSRLPVYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGG7</accession>
    <name>A0AAD8XGG7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_227125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000027">
        <property type="protein sequence ID" value="KAK1727064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367119.1">
        <property type="nucleotide sequence ID" value="XM_060501777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGG7"/>
    <dbReference type="GeneID" id="85385676"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="171" mass="19508" checksum="E878B0458FCEEBB4" modified="2024-05-29" version="1">MQKAMCGVCCSSLHSPRSDSLAWILERFCSCVFFIAWGDCDLRVHLFIQNIVYIFFTPNIRSLLEMAEVLGIVASVAALIQLAKYGEKFAKVLIRYSKQSSSPGKEVERCAFQAQDFSDCIDMTQFALERHFDKYTESSLLQYLLSQGILQGILNRSKLIKWQLEMATKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGJ2</accession>
    <name>A0AAD8XGJ2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_730368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000041">
        <property type="protein sequence ID" value="KAK1725461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365516.1">
        <property type="nucleotide sequence ID" value="XM_060512842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGJ2"/>
    <dbReference type="GeneID" id="85396740"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103:SF2">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1725461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="57437" checksum="0B36B4344E0AED01" modified="2024-05-29" version="1">MLPEPTLSFTLPSLHDDTVLDCRLYHCQALNPSATNPPPWRRHAAVVAHPYAPLGGSYDDPVVDIVAATLLRQGFLVGTFNFRGASGSAGRTSWTAKPERSDYMSFIGFMVYYIHFLDPYGATNARSPTTTLSPGLPDAQSKSPSYHPLLLIGGYSYGAMVTTQIPPMAHILAQFKVPAAGSAAADIRLRAQHLAEQQNVILASARAASSVSPRKKYLGMRVGGDEDTQRKSHEARRSMSETRRSFSIDAEDKIRRGVNDLLAKTKRHHHKGVAVPQEKLATIPSNHEVSVVVEEVPNLIQVRPAYLLVSPLQGVITHLAAMSFLHTTPGRGLFSRGGGRLREQGAPTFTADQKHQSESKLVENDTLALYGDRDIFVPVAKLRGWVERLEGNDGSHFHGEEVSSAGHFWTEGNVASVLRDKVSEYAAKLLQGADESRPASEPAPNSTLEARIFPCVTRWKVRGLHGLVASFPSRWPALLAHSYRAVVPSDLRDNDVWSVTDAANRKWGDEQNESVSWQGHNGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGN3</accession>
    <name>A0AAD8XGN3_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine rich repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_573069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367329.1">
        <property type="nucleotide sequence ID" value="XM_060504585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGN3"/>
    <dbReference type="GeneID" id="85388484"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1727274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="336" mass="38060" checksum="CA8384FB51EFB7CF" modified="2024-05-29" version="1" fragment="single">HIDDDLGAEVLQKLFFGMPRLQALDFAGCTSPSFKNSFASLVDMDWPETLSITRLSLHKCLTLPPALFEKIMPRLTNVTHLDLAQTKITDRALQAIPKTARITHLNLAKCTLLTAPTVINFLATHPAVRNLVYLSVATDARSHQLLDVEDVSQLIPVLPKTLRSLSLKGSRMDDSHLELLRPLTKYLEELAVGRDMDVNAAAKLLEPADEKKQEEPHMIRYLDLSDLWGSELDIVDLFSSRNSLLKPSSVPLEVVEISEQSFKSLSRNRALERVGWSLQEIGSRCWMVRMQDHRKDQDRGYRWWKIGADNWGMRKIPVARAEVGGMYGSFMFGRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XGP3</accession>
    <name>A0AAD8XGP3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Vacuolar ATPase assembly protein VMA22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_572768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000025">
        <property type="protein sequence ID" value="KAK1727304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367359.1">
        <property type="nucleotide sequence ID" value="XM_060504545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XGP3"/>
    <dbReference type="GeneID" id="85388444"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990871">
        <property type="term" value="C:Vma12-Vma22 assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040357">
        <property type="entry name" value="Vma22/CCDC115"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31996:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21730">
        <property type="entry name" value="Vma22_CCDC115"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1727304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="243" mass="27279" checksum="C44F009714A5EA42" modified="2024-05-29" version="1">METNHVDSLLERYLVLLDEYTTLRERLSRTQAGMYQNIARANFSAERGVRYGPDYYDERMRASRTLELAVDDRGVPRFEVVRAAEGDDAVTEPRTETTEAAAAAAAARRNDDVDEAPSMEAEGVTSVGEEQMEKEAEKEEEVEKENEKAKQKKKKKSNDPLRWFGILAPMPLRQAQTLSVQAVQDIVPRLVSVDAEMKDIEIEVRRARKRRAKAEAAALKSNDVDEGVGTVRQETQVPVAAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XH03</accession>
    <name>A0AAD8XH03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_407500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000071">
        <property type="protein sequence ID" value="KAK1723030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363085.1">
        <property type="nucleotide sequence ID" value="XM_060502887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XH03"/>
    <dbReference type="GeneID" id="85386786"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000008">
        <property type="entry name" value="2,3-dihydroxybenzoate-AMP ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF32">
        <property type="entry name" value="2-SUCCINYLBENZOATE--COA LIGASE, CHLOROPLASTIC_PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="410"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1723030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="499" mass="53593" checksum="1AC147A68295F7F0" modified="2024-05-29" version="1">MEFHAPDPVQLHARLRPNGLACIDVATNRRWTYAELNADIQRATAVLSEQGVQIGDRVATISVNNVHQIILQQALMRLGAIHVPLNWRLARPELAKLLADCTPTILFTDHEDPPALPLGCRHIGFSTFCVSVDAAEPGPRLSARPLHETCIILYTSGTSGAPKGVMLTGQSILATTFNFSILTEIDTGSVFLCDGPMFHFMGLIAQIWPSLMRGGALIVSSKFQPETTNARLSDADLGVTHYFCVPQMAEALAGASNFNPSAWSALKALFTGGAPNPPARIKWWLSRGVRMVDGYGSTEMGTCSGMPLSAELISSKAGSVGLPGPLTAVRVVDGGGQEVPVGEPGEILISGPSVTPGYWNRLDDNMAAFTEDGWFRTGDIGRVDEDGYVFLIDRRKNMFISGGENVYPAEVEAALAEHPGVLDAAVVGVPDQLWGEAGRAYVIVAPNSQLTHGDLVSHCQSLIARFKIPRETVFVGSFPRTGSGKVQKHMLTEDSVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHB4</accession>
    <name>A0AAD8XHB4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Choline/Carnitine O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_572855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000026">
        <property type="protein sequence ID" value="KAK1727257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060367312.1">
        <property type="nucleotide sequence ID" value="XM_060504559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHB4"/>
    <dbReference type="GeneID" id="85388458"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.20:FF:000003">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000019">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000025">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000003">
        <property type="entry name" value="Carnitine acetyl transferase FacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.20">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042572">
        <property type="entry name" value="Carn_acyl_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="9">
        <location>
            <begin position="79"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="599"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="836"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="637"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="796"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="836"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1727257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="869" mass="96238" checksum="CEB2D00D2D644432" modified="2024-05-29" version="1">MPTQVRIFSRPRPLGETLEKAVPPSSVPRSIPDTSDLWKQVEPSKPKQSTEATRSMAVYTDKSVEGGVTFAAQEKLKHLPIPELEATAQKYLVALKPLQSAREHSETKQALQDFLKHDGPALQEKLKTYAQDKTSYIEQFWYDSYLNFDNPVVLNLNPFFLLEDDPTPARNNQVTRAASLVVSALEFVRAVRKEELPPDTVKGQPLCMYQYSRLFGTARVPTENGCQIEQDPESKHIIVMCHGQFYWFDVLDDNNDLIMSEKDVSINLQTIIDDAAQTPIQDAAKGALGVLSTENRKIWSGLRDVLTREEGSNNADCLGIVDSALFVLCLDYTEPVDADALCGNMLCGTSLVEKGVQIGTCTNRWYDKLQIIVCKNGSAGINFEHTGVDGHTVLRFASDVYTDTILRFARTINGQAPTLWASTSPDPAKRDPDSFGEVNTTPHKLEWDMNPELSVAVRFAETRLADLIEQNEFKTLDFKHYGKNFMTSMGFSPDAFVQMAFQAAYYGLYGRVECTYEPAMTKIFLHGRTEAIRSVSDESVNFVQTFWADNPAEHKVEALRKACQRHVNSTRECAKAEGCDRHLYALFCTWQRSMDDELSGSSNGYSSPIDALSEQDVSESAVGSPGRDSVLSLNGAELQSSSTGRARGDSTNSRNGNNQASMPQIFADSGWDKLNNTIMSTSNCGNPSLRQFGFGPTSGDGFGIGYIIKDESISICVSSKHRQTKRFVDTLESYLLEVRRILRITSRRGTGGAGMGAAKQTRARELDLQARPKPPKGIKSRGRLITAHDAIKPSVARSSTGTQSPTEESVTLSEDDELGGYGFFDAGMLLQALKARGENMDPGETKPSERAAVQARRREIGKKLRLIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHJ7</accession>
    <name>A0AAD8XHJ7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_720573</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000063">
        <property type="protein sequence ID" value="KAK1723585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363640.1">
        <property type="nucleotide sequence ID" value="XM_060512286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHJ7"/>
    <dbReference type="GeneID" id="85396184"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="524" mass="60182" checksum="77C1043DD2D25BE2" modified="2024-05-29" version="1">MGFTKVEMPAPENGAQSSGPRQALPKGLVATRFNNYPTSSSPRHHLSPSSTVTSSSFVECDLIDIGADISSPSREFSEKDVLPNARDGEDEAEASDDFLLRRGIMELRHRLKSTTARAEIAEEKVERAERRIGEIKSTVNSTITEIEKDTAPLASKINELSTENAALKEQLRDAQSHIFSLQPYRKELTPEEVGREYDDLIEGISDWVSKFMDPYLDDHEKGVEDLMAAARRRPSDALKLKQVIHQYPDLVHGAVFPETDEDIVVATIMRFINENIFQKVMYGSIVNYVEVLSFVETALQNHVDPKRDLFAIRTWTAEAYNAILSSRDFKGCREKKLRELTIELASIFKIFCRRDKIDAFYRSFEQICIKPAMQLYEKIQVSTNHFYFDINPYIVWGGDGEMQTSTDFLDNLQDLDCKNILLNRKAFNLARIDPRPTKKELYHHLLNVCTLTPALYMRQIGRKDVIKEPQLVRRQQMLVAWGPQEKRDRFQENGDRTLLSHLYYAKSDRERQEAGGWTNFRWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XHN5</accession>
    <name>A0AAD8XHN5_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Telomerase reverse transcriptase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Telomerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_251301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the reverse transcriptase family. Telomerase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="JAHMHS010000030">
        <property type="protein sequence ID" value="KAK1726706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366761.1">
        <property type="nucleotide sequence ID" value="XM_060501928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XHN5"/>
    <dbReference type="GeneID" id="85385827"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000333">
        <property type="term" value="C:telomerase catalytic core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003720">
        <property type="term" value="F:telomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003545">
        <property type="entry name" value="Telomerase_RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066:SF0">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0158">Chromosome</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0779">Telomere</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1726706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="419" mass="47265" checksum="E686C338281A12EC" modified="2024-05-29" version="1">MATKRKFLALEGPKDERSGNKKSKSIQIKGQVRHTLLQQHYDVVQTLREYLLSKLPGPSRLRRKKIAALGKYEAPWARIQDHDIIPELSSLLDTTLVCTQHRAEAQADSRWEQWRSFSQKADDSIVSLSGELAQATSSQSEIVDFVVWQIFNRHAARPKHLLCDGFRRQAQNITDTKGHNRDSGIQGLVAVDPNHYVQALKKAPWPQVLMLLGKSGEQIMIDLLIDTAIFLPVRAGLGNMYQLSGIPMSETGVAANQDIKKQTKGDATAPPPIPQERLPSEISFIRNRMLYARAALTAKGTVQYGMRHIHVLSRCPRLSCSEQAPEEEKSRTTQSNERNTLKVMMYIFPRQFGLHNAFTSRVDHSKTSQSFQGDCAETQNDWYRGYNFSTVVVLTLRYCGTIALLPLMSKPGNPSQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJ95</accession>
    <name>A0AAD8XJ95_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_275480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000036">
        <property type="protein sequence ID" value="KAK1726000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366055.1">
        <property type="nucleotide sequence ID" value="XM_060502092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJ95"/>
    <dbReference type="GeneID" id="85385991"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42090:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1726000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="138" mass="14093" checksum="42AB73F4A996806E" modified="2024-05-29" version="1">MASQALLRSLNLRATAHMPFRASLPTAATVTRPFTASSTTKFAYKDTQDRESLNPASNEGTKTGRDTEVAHEKEAFDPSTTRPKGEKSEDSGTLDVSGANQAASKPQGDNPGGKGAGRKEGGGEGSSGAGSAPKAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJC8</accession>
    <name>A0AAD8XJC8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_697024</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000034">
        <property type="protein sequence ID" value="KAK1726240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060366295.1">
        <property type="nucleotide sequence ID" value="XM_060511378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJC8"/>
    <dbReference type="GeneID" id="85395276"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="11">
        <location>
            <begin position="198"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="663"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1726240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="820" mass="90558" checksum="C1B5E1769811DC41" modified="2024-05-29" version="1">MSTLTNGVSSHRAESDNAADGAHSSTAARPSSSSTNSIYAASNVAEVRAALEALHVRESTITSRLDALLGSQADLARELGRLDLLRAGLGSQVIAARSVGNDMLSTAADTAGRLSNKVKELDLEKSRVEDTLEVVKQVVELKACVQGVVGSMGAPQDWEAAAAYLARAAQVPEDITKGKFASSIVPSVEVPDPPWVTLENAKESLCGLFLREFEKATKEGDGAKVTRFFKLFPLIGRGDVGLDVYGRYVCQGVAGTARSVLKESPGVQARKEGFFYANALTRLFDHIARIVEGHGGLVELHYGSGKMVRVIERLQQEADVQGGIVLDSWSDERDVDRRLKDVKSYPFSFLVQSFLPQQRGGTPRVNSPAMGAGANPRASEDEGVNMKEVDGLLSEIAIMLGRWSLYSKFLAGKTRDPSAPDDAPLSVPEVVVKSNLRKKVSDKLTSPYNIMMTFFFRRSVEKAFQLDESPASSLSLSMNKHIDTNQAFIISAVDDVMYVVSAVIQKSISTSQRDVISSVIPTIGRVLGSDFVGMIQRKMRDESYPKPIVQGGFPPEDRIIQFIVLINSLDTANEYLGRIITTNVGSTNDPPKANGDAHEPSLKDTFPFDKDVAFVASALNTLQSSFTTKTTELLNEGLQVLFKQVVQPRLRPVLSDTFRDVDYSLTEEELAEFAQQNDEDEEEMLDQVSRRFEHGWDQLMKPVARLMTPHTFTTLHDLTARYLSRVLERRVWDARANAYGVIRMERDFSSIVSTVSKGNYGVRELFARVSQILMVANMEEEEWEEISAQPDDGEEDGMIWVLTEDERRRARHLTSRERRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJH2</accession>
    <name>A0AAD8XJH2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_560085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000019">
        <property type="protein sequence ID" value="KAK1728098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368153.1">
        <property type="nucleotide sequence ID" value="XM_060503553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJH2"/>
    <dbReference type="GeneID" id="85387452"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="183" mass="20633" checksum="D4EB8C3D16F455CD" modified="2024-05-29" version="1" fragment="single">SDSKGLVRKLSRTALRIAQGHRERHQDRAPITHEQIPEMAELGSPRAHRDRNHHRHTIEGPLGVGRAGEMDHSRSARRATTGDILLPFESGASSPYHLDDPEAADHNPYEHRVDWTQSDEAQPQPKTKPSLRKADSIWALKHKLGALTRHGREENHSRDNSPPSDTALRSPKSGFFARFKVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XJK2</accession>
    <name>A0AAD8XJK2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA mismatch repair protein MSH3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 10">DNA mismatch repair protein MSH3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">MutS protein homolog 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BDZ83DRAFT_570830</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Heterodimer consisting of MSH2-MSH3 (MutS beta). Forms a ternary complex with MutL alpha (MLH1-PMS1).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000018">
        <property type="protein sequence ID" value="KAK1728338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368393.1">
        <property type="nucleotide sequence ID" value="XM_060504346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XJK2"/>
    <dbReference type="GeneID" id="85388245"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000870">
        <property type="entry name" value="MutS protein homolog 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF21">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="12">
        <location>
            <begin position="779"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="737"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="748"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAK1728338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1005" mass="113781" checksum="43D47F66D8550FB5" modified="2024-05-29" version="1">MEPTHLLIVSSCCPPNPKSRLYSHIEEHMPDAKITSLDRKYWSEMDGLNRIQTFAFREDAEAVKVAIEGSFYATCSFAAAMSFLETEFSVRVVSHSLRIRYQPSEDTMMIDVSAIMSLEILQNRRHATSNDSLYGVLKHTLTPMGGRVLRSNLLQPSTLKESYLEPRYDALEELLANQDMFAEVRTALKAFPDVESMLTKLVIIPNKPSVEASERAINHILVVKTFIDAVPPVFQALGPATCPLLAKIRDLCRPELTAAVRELVYQNIHEDVHYVKGALDLRNQRTFAVKANWLTMQQPGINGLLDVARQAYKENTDDVHKHVEELNREHRIEAILRFDNGRKYSLRMRAVDFEDRAVPAVLVNQTMKGRYIECLTMHLKKLNQRITDSVAEVVMLSDKVIQDLIDSIRTQLQPLYRVCDSIALLDMIASFAQASSTYDWRRPEISDTLALKAARHPIMDKTLKGGFVPNDYYAAEEHRFQIVTGCNMSGKSTYIKSVSLLQIMAQIGCFVPVEYASFPIVHNIFARVTTDDNIESNMSSFSLEMREMAFILSNVTHKSIVIIDELGRATSTRDGLAIAIAIAEALIQSRAIVWFATHFTELADILADRPGVLNLRLVTQVSTMDNNVPKLTMMYKVESGKTEELRYGITLAKAMAFPKRFLEVAEEVAMSLHQRREQNKQSSQARKMLNRRKLILNLHEQLKQVRNSEMDDSSMRSYLIRLRKEFVLRMDAIENGGNQSSSTASEALGDEEDGEYGEFDDEDVIGAVDADLWETKKGADILLIMGDSKWELHDKVVRGRSGLIDHILGMVQMKEGLRKIPLKERMFPYSALNTVLKYFYFGESLITEKSEVIDLLSLYEVSATLDILPLQERIAFQTGNLLGEILSSGTDRMGDFYIVVEVIIAEQDSSWVFMHEEMQRALSPYFLKLLQQDTFVDLIKQNPAFCLQVLFTAIDRIEILEDAAKEATSVKGVSDAGTHAVIEHGSDISRRYGRYLAVGHQLCLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XKF0</accession>
    <name>A0AAD8XKF0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_648330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369052.1">
        <property type="nucleotide sequence ID" value="XM_060510170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XKF0"/>
    <dbReference type="GeneID" id="85394069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041938991" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13702" checksum="7CEDA9675B36F309" modified="2024-05-29" version="1">MGLTFRLCLCSLLCDGWSLVTQSSWAVSTAQLSLEDPWNFGPVDRTEADRQTRPRFKKSCYGMDDDLRGKVATPEATLSHASFMVGETMVHGSVSLYQSVRRRVQGAGAKKCSSEPEGVANLLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL38</accession>
    <name>A0AAD8XL38_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_568633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000012">
        <property type="protein sequence ID" value="KAK1729375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369430.1">
        <property type="nucleotide sequence ID" value="XM_060504097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL38"/>
    <dbReference type="GeneID" id="85387996"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01830">
        <property type="entry name" value="XynE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053140">
        <property type="entry name" value="GDSL_Rv0518-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784:SF3">
        <property type="entry name" value="GDSL FAMILY LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43784">
        <property type="entry name" value="GDSL-LIKE LIPASE/ACYLHYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00820)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042057965" evidence="1">
        <location>
            <begin position="23"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="225"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="438" mass="46266" checksum="E1C79561D2D09D63" modified="2024-05-29" version="1">MMIASLKTAFAALLFLSPLAEARPQHPARDEREWVTVWGTMPQLVEPANLPPAPFNETGRVFHDATLRQTVKVSLATSTLRLQISNAFGGSDLPITAVTIARTANNTAGTSGVDADSLQVVTFSGSGGFVVPNGAIVFSDPIDLAVEAQSIISVTIYLADGQTTNSITGHPGSRTTSFLKSGNHVADQDLATTAGNATATTTDHWYLISALEGWVPKGASAVAIVGDSISDGRGSTTNANNRWPDRLLARMQNESSTSGIAIVNEAAGGNRVLADGLGPNGLGRIDRDVIAQSVIKYAIVFIGVNDIGTATNTTAAQEAVGDRLVAAYDQMVTRLHRFGIAVFGATITPLTGDGQPYSDPTREAARQRVNEWIRSSGRYDAVIDFDAIVRDPAAPEKLRAEYDTGDHLHLNPAGYEAMAAGIDLSIFEKFKDGVSGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XL58</accession>
    <name>A0AAD8XL58_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidative stress survival, Svf1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_605004</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369460.1">
        <property type="nucleotide sequence ID" value="XM_060507307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XL58"/>
    <dbReference type="GeneID" id="85391206"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Svf1-like N-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="5">
        <location>
            <begin position="216"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1729405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="381" mass="42160" checksum="DC144A5A2881722C" modified="2024-05-29" version="1">MFKWAQQKLADVAGTQEPIYGPTAIRSVAEEAKTTTHTETTKEDLKWIAADSTSVETQSFYLMGDNGHLGLAQIIYSNVGGIRTTCQFNAKIFYPNKSKPTLWETTQLSHYEVSEDRMSFYADDCAVELSEDGTYYTIKSMNSENAIVNLKVTRMSPGFHAGKTGKTLFGTDMSKPWGTMRHAFWPRCITEGTITTKDGAVDFKGRAFYVYALQGMKPHHAAAKWNFVDFQGPNYSAVMMEYTTPPSYGSTTVSVGGIAKDGEMIYGGVTQTAKHTKAKNDSVNEWPEPEEIKFTWSGTDKDGKAVEGIIEGPLGERLDRVDVLAEVPGFVKKIVAGTAGTKPYIYQYCPTEKKLTLKLKIGDQEISEEGLCFSEATFISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XLT9</accession>
    <name>A0AAD8XLT9_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_727086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369781.1">
        <property type="nucleotide sequence ID" value="XM_060512772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XLT9"/>
    <dbReference type="GeneID" id="85396670"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="908"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="947" mass="106240" checksum="A9801F770BAD348F" modified="2024-05-29" version="1">MRWEEGRNFREKPVPAPNRSPWFKSDALSPYILVQILLEVSALLHQHCRNQQLDSKGGITPDKKTGGSIIQFSHVGKNLGKSLDLKLSASAKPFIPAKRSGEQSTPLSHDEKDHGEDFDLSISVPKGPVTNEEHIGEHENQSRHGENKCGKFECIDLTTSNPAESIVLKNQTGNKENQYIHEERSCGDHFFLKFAKEPVSTEKRADDNKSQCSHDEEHRGEGISRIDSPYPWSSVGLYPQKAGSARFTFYPPSPAVVVSSANEKAKAAALSSNSPSGKPTQPIKRSTSIRWAMNLPVPQRRLTPPAFLNDPTSSPEARRISFEFNTRRAPGGDIYNAGLENADYDYLAERRAYVARSFERTRRQREAKIAAQRLKIQSDADDDDDGTMASTLPMPSDYIPPHKRLAKTKAKAGAKAESKIEDPVTENQEPATTTSYYAESDTASSTDDASSRVSLSGTLKKPSPLTPMALENLPERMGVTTKSKKSHSSWDVSNNGRASPVQDREDPNKVARSETKVAGTPSFLTWLYTLDGPLVTSFLDENQDHHHHDVSTDTGKLIDRIEQPPTKADIVDEKDMTPEMIQRRREWTSNLIVHREIMVRKNIAIRQRLQEEERAHHEIAILRDRDYKRDAATPTKMRTAVAPTLDGNSRLADCVLRPAQHSDAEACAEMYNLAVGKDHLVTDTYPVSVERFEYIMIECKRQKLPFIVATTKTTDLTDPGNWPSRDGYRQYMKWMQSQPAKVSSPETTVYGFAYLRPYETGIGGLTGNATPTVKATIFVHPEHRGGRIGSALLHQLLSQVSILYHGFVECQWADPKAGEDALYKPDFRDIHRVIVHTMAQSEGEQGLKWMDDFMSSFQFEKAGRLNQVYKVKQPHGADWYDQVIWQHWANKIACKTFYVADDSECSYDYPGKRHSPGARRAKSPDTPKDQQHDDGSHDSDSDDVFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XM03</accession>
    <name>A0AAD8XM03_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_16851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000010">
        <property type="protein sequence ID" value="KAK1729784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369839.1">
        <property type="nucleotide sequence ID" value="XM_060501445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XM03"/>
    <dbReference type="GeneID" id="85385344"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1729784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="309" mass="33895" checksum="9D40AF7A6BEAE088" modified="2024-05-29" version="1">MTKLRAESQSEFWFRIWEVAFPDEPRPLSPYRDDVQRLAYRQQVEPRMAETTWRIGRQHGVEDHVIEQLVRGITDSFNAVQTTSHSPVEHFDPSPNAPGIHEQPASSSSQQLRPASPSLLAQSQALVVSTASITNPILSHTQASMTPNPVNVGELHPHPTSSTLHNTFRPNSQRPYSQALTANNSALPAQNRVIAPSILNSPAYPYPSVPYMNEQSPFSMNTAFTANYLLQHPYGSSHGLSNEYFSGQGPGNNSAVSDDTWVLAGLGDDLASFTNMPGNDAVQTTSNLLPPELRHCECETGSTCPRHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMC1</accession>
    <name>A0AAD8XMC1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L24e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_567238</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370103.1">
        <property type="nucleotide sequence ID" value="XM_060503938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMC1"/>
    <dbReference type="GeneID" id="85387837"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="158" mass="17571" checksum="5AF862F6E7B91C18" modified="2024-05-29" version="1">MRTYDDTFSGQRIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHRKGISEEVAKKRTRRTVKAQRAIVGASLDVIKEKRSMRPEARSAARAAAIKESKDKKNADAAAKKAEKAKSAAAGGKKGPIASKQGSKGAAPKVQARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMD6</accession>
    <name>A0AAD8XMD6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RhoGAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_567313</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370170.1">
        <property type="nucleotide sequence ID" value="XM_060503942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMD6"/>
    <dbReference type="GeneID" id="85387841"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07652">
        <property type="entry name" value="F-BAR_Rgd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000063">
        <property type="entry name" value="Rho GTPase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF136">
        <property type="entry name" value="RHO GTPASE ACTIVATOR (RGD1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="64"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="579"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="210"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="368"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1730115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="774" mass="84336" checksum="77073FCE13EBF5D7" modified="2024-05-29" version="1">MADLRSPSDDNLPSHNEQRDRASSMSLGNTETVAPSQNGGAATANGGAPAGTETGSAPTSEVSRQVQEVLSSDIGVATMLNQLKASIASAKEFALFLKKRSHIEESHASSLKKLSRISQETMHQPDHRQGSFAQAYSEMMYIHERMAENGTQFALSLQQMHDDLLELAAVAERSRKGWKANGLAAEHRVAELEAAMRKSKAKYDSLAEEYDRARTGDTSRNSGKMFSLKSKSGPQHEEDLLRKAQGADQDYQAKVQTLQSEKAELIARTRPEAISALQDLVKETDSGLALQMQKFASFNEKLLLSNGLSISPIKGQGSSGGPRSLREAVLAINNEKDLHDYLTSHHSKVANNNGEVKYEKNPILATARQQAMGHQPNASVSNVPQAAPSGSFSGPPGGPNQQQQRDMPPPARPGNFQPPSDSPQSFAPPNMPAAQQPRPSSQQQHPPPQAQQHGRSFSTNNMLNQPSQQQQFQSNRNSGVVAPTYNNGGMSSQGPPQLGALPFQTSQSPPPPQQEPQQRAPPPQSQYQPPQQHQAPPAQQYPQGPPPGAGGYPQQNRQSPPLGGPSGPSPNAARPTFGLSLPRLYERDGLPVPMVVYQCIQAVDLYGLGVEGIYRQSGSLTHINKLKTMFDTDSSNPALDFRNPENFYHDVNSVTGLLKQFLRDLPNPLLTTEHHSELIEAAKQEDDIVRRDSLHAIINSLPDPNYATLRSLTLHLHRVMENSHVNRMNSHNLSVIFGPTVMGTDPATSIADAGWQIKVVDTILQNTYEIFDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMH5</accession>
    <name>A0AAD8XMH5_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Importin-beta domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_426633</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370230.1">
        <property type="nucleotide sequence ID" value="XM_060503011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XMH5"/>
    <dbReference type="GeneID" id="85386910"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000244">
        <property type="entry name" value="Nonsense-mediated mRNA decay protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="882"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1730175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1017" mass="116040" checksum="5C41ABF1EA1B6A7C" modified="2024-05-29" version="1">MDVLLEVLQNEQDNSVRLSTVIYIKNRVNRGWEKSDHNPNDTQIAEDEKARFRDRLLPIMAASQGLVRQQLIPVLQRILHFDFPEKWPNFMDYTMQLLNTNDAASVLAGLQCLLAICRAYRFKSSDGDNRVHFDKIIEASFPRLLAICNELIAQESDEAGEMLHLALKAYKHATWLELSAFLRAQQTNFGWCTVFLQTVSKTIPASAMADDSYEREKHHWWKAKKWAYFNLNRLFIRHGNPQSVTNTKDEDAVRFAKEFSATIAPEILKHYLAEIEKWVAKTAWLSRPCLSYTLVFLDESVRPKEMWNHLKPHLQNLVMHFVFPVLCLSEEDIEKFEDEPDEYLHRKLNFYEEASAPDVAATNFLVGLTKNRRKQTFEILKFVNAVVNEYEQAPEDKKNHIAKEGALRMIGTLAPVILGKKSPIADQVEYFLVRYVFPEFTSQQGYLRARACDTIEKFEQLNFQDQNNLLTIYRHILDCMADVALPVRVTAALALQPLIRHDIIRTSMQQSIPTIMQQLLKLANEADIDALANVMEDFVEVFATELTPFAVALSEQLRDTYLRIVREVLDKNKDNGEDEFGDYLDEKSITALGVLQTIGTLILTLESTPDVLLHIEAVLMPVIQVTLENKLYDLYNEVFEIIDSCTFAAKGISPTMWQAFELIHATFKAGAELYLEDMLPALDNFVQYGAGQLVQKPEYIEALFSMISDMFNDNKVGGVDRICACKLAEAMMLNLRGNIDNYVLRFIEFAMTVLTAQDVKVKAYKIHLMELVINSIHYNPILTLHILETKGWTNRFFSLWFGSMSNFTRVHDKKLCIVAIAALLSLKADQVPQSIAVGWPRLLQGVTELFKTLPAAMKNREEALRDDYHLDAGTYDYGEEDEWAEDEANWNVEDEPEEEETNEGRDESTAYLEFLNEEAQKFSRGVDDIESEDDLGEDSVLLESPLDKVDPYQLFSATLMKMEEEQPQFYQSLASHLTAEDQAALQGVMQKATENAQAAQLALAQQQGAAPVNGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XMM4</accession>
    <name>A0AAD8XMM4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase zeta catalytic subunit</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BDZ83DRAFT_603157</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="JAHMHS010000008">
        <property type="protein sequence ID" value="KAK1730129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060370184.1">
        <property type="nucleotide sequence ID" value="XM_060507211.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85391110"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.342.10:FF:000018">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000024">
        <property type="entry name" value="DNA polymerase zeta catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="21">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="20">
        <location>
            <begin position="61"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="19">
        <location>
            <begin position="869"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="18">
        <location>
            <begin position="1120"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="509"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="576"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="619"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="835"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="850"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAK1730129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1299" mass="146664" checksum="AD2819BC29051E5F" modified="2024-05-29" version="1">MDLFRVRLNCIDHYQATATHYDPQLRNDVGPAQAKKGPKVPVVRVFGSTETGQKVCAHIHGAFPYVYVEYRGSLEPEDVGAYIYRLHLSIDHALAVSYRRDQFGENAKFVARITLVKGVPFYGFHVGYRFFLKIYMFNPIVMTRLSDLLQQGVILKQKFQPYEAHLQYLLQFMTDYNLYGCGYLDVSDVYFRGPIPSFDQEGNSQHLWHDRTIPKTRVLDDLTLPRVSHCSIEVDICVQHITNRRMVKERRLHHDFVERVKPLPADIKLVYSMAGLWKDETRRRKMKMPNADQGSSPFPAEVLVSMSANKRDSQPQGWIHEEEYKEEVAKLIETEKGLEDSEPPSFETFVEHSPLEAAIKTALQSVEDLYPVNLLPALGLPSNHPPANKNPASSIEVDEQGVLDLGVDDYDPYPADSDEEALIQMGEPKARQDGQISDSGIDGRRSLISGNKSRSVPVAGDLKVMKTVNGLGSLYEGVCASRLKTGNPPMVPVWDDLLDMAEEEGLVSKLSDPSSLGHRRTVSVKRSISPHAIAPSTKRPRTETSVAPASDAVVPKPSLKGILSNSAASEKHQITMLPPNSQDKPRSSQNAGSKSAANQLLGFPVVKSQEDPGTKLRLSQMNQPRASQQAEQDSQKHVAFSLAPQETRSKPDSVTPAKKVRIATPTTDSPGTEAGTETILHRIQTAIGSFSAKRQCVIGVLPPAPKVITSTMEDLQIPDMIYQDAYYSEEKDVPARPREYAGREFRLESNTLPYLADFDPTGTSAASMGIKSDTPIDKAKNDVRYDAQASLCSYRSWEIAQPPPSAKDVQDWWNKKHHVLKEQKNVTAKIMGTPRATRRDLSQIEGPTPKNKHGFKYSPKKKSTSVKHEAQYMSTMALEVHVNTRGKFVPNPDEDEVQCIFWSIKADGTASSSQEASGGIIAGVVVLSPDGSLAQRMRRFVSAEVIEESSELDVMVRMVQIVRDHDPDILTGYEVHGSSWGYLIERARVKYDYDLCDEFSRMKSNSYGRIGKENDRWGFNTTSTIRVTGRHMINIWRAMRGELNLLQYTMENVIWHVLHRRIPHYSWRTLTQWYNSSRQRDLDKLTRYYLTRTRIDIHILESNELIPRTSEQARLLGVDFFSVFSRGSQFKVESIMFRIAKPENLMLVSPSRKQVGGQNALECLPLVMEPQSDFYNSPLLVLDFQSLYPSVMIAYNLCYSTFLGRIVNWRGMNKMGFTEYQRHKRLLELLKDHINITPNGMMYVRPEIRKSLLAKMLGEILETRVMVKSGMKQDKDDKTLQALLNNRQLALKLLANVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XPI6</accession>
    <name>A0AAD8XPI6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Misato segment II myosin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_715068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the misato family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371230.1">
        <property type="nucleotide sequence ID" value="XM_060511708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XPI6"/>
    <dbReference type="GeneID" id="85395606"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06060">
        <property type="entry name" value="misato"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="6">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="7">
        <location>
            <begin position="118"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="522" mass="58045" checksum="CF5523595FDF9C1D" modified="2024-05-29" version="1">MHEIITLQLGQLSNYAATHFWNTQESYFTYSDQDESPVNHDVHWRPGVALDGSETFLPRTVVYDLKGGFGSLRKINALYEASQEEAPAHLWEGSAQVHKQRPVEPSAYQKSLDLGTPAPKLKSSDVRYWSDFSRVYYHPKSLNQLYDYEINSSIRPFDKWSLGRELFDSLDKEHDIVDRDFRPFVEEADQMQGLQIVTTIDDAWGGFATDYVERLRDEYGKTTIWVWGLQTPVPAARIDQRRLQLANTARTVKDMCEHASMLVPMALPQTQLNSNISIDMQSPWQTTALLSTAMETAGIASRLNSSSSGSGLQATLGELVSGLNLRGRQTMSRLQMTVVDPATETIQDIRAPESGLDDDEAGEITKLDTDLFDILRSKSIPGRRNMNGGGGKAHLFGQTITTRGSQQVLKHDEGEGSDGRQRPRATLIETSTQRYLTDKGFPMLDSFPDIYLDGSGKPLSESFGVKTSLSTDTSVSAALNALRTTVASSLGVEDREDISNELADFAEAYREGWSSGSDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQF7</accession>
    <name>A0AAD8XQF7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_746424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371536.1">
        <property type="nucleotide sequence ID" value="XM_060513268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQF7"/>
    <dbReference type="GeneID" id="85397166"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1731481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="279" mass="31410" checksum="93156AD3F606C503" modified="2024-05-29" version="1">MSSKLIPQNPADVMVIRDLTPNITTFSVPFSRFGTLKIGGRATLVRLTSGSLAVFSPVALTDAVKAKIAEKGGNLAYIIAPDMEHHIFISEYKAAYPQAKIIGPDGLPQKRAKQTGDPKINTSDEFFVVFKDGAEKRSTTITPEFEADFEYEYVDAHANKELVFYFKPERVLIQADLLFNLPPREQYSKAPEGERDTSSGFGNKLFGGLQTTEGDVKWVKRFQWYVMSSKDRPSFNESIQRIDAWDFDTLIPCHGDTIQGDGKERFRKVFEWHLAGTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8XQR8</accession>
    <name>A0AAD8XQR8_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_686990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000001">
        <property type="protein sequence ID" value="KAK1731733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371788.1">
        <property type="nucleotide sequence ID" value="XM_060511275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8XQR8"/>
    <dbReference type="GeneID" id="85395174"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="236"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="847"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1731733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1206" mass="129938" checksum="81C0E6098E99E1A0" modified="2024-05-29" version="1">MNRHHAQFVAGPLQRDHYFTPVTGLSFFNARDGETYLLAGEDTELKVYDGEGRLRCQLGIFHAQPIHGIHVAAAAAGHGERRHVLLWGNQAVTVVSAAVIEELILGSGGEDEAVVAATPVEIIEAKAPDWIYDGVICPEDPDRGVLITAHNEVLEFSVAADGKTISFGRIVSPSRPILYSANLTWLSETSVLVAGGTVFGEIIVWKCHFSSSDGAATASGEDAASMKPWCEALFVFTGHEGSIFGVDISREIDLGGGCTARLLASCSDDRTIRIWDITERPGSPRLQYDAFGEARETGFGGSSSSSAPAAAAAAATDLTTTQVASSAPLTMVMGHISRIWHVRFPLGGVDELARGRPVTVYSFGEDSTLQAWSLDVDLEAWRRRAAKSAATVEGCEAPIIAASITYKETYARHDGKHIWATAVTEEADGRVLIATGGADSKINLFSDRSRAAGGTGTGSGSDISTTASKLQELPSELQTLVMRDVVSKLAPRSPDHAIPLETKEAFQRFAFVYEDTIVATSTTGRLLVGSFGPELTWAQIGTDGETLRALNACTSLKSPAPGLALIGTANKKILLHRDSTIQQVGTVPGKVADIFPLRKSPAEDGGASDKKLEFLVTMLGSGDAMQILTLDLDAAAVTSMVPVPELDSRFVVTAACQINDLLVLGSRHGYVSVFRRVEDEQQLIPFPAPDRRSGDAITSINVLPTSSTSGAAASHIITTSRDGNYRVYETSDSAIQLRHETAPAAVPNLEDAWLSDNGDLILCGFRSKNFIVWNETRHEEILRVDCGGAHRAFAYTRQSHHDKNTDSDSNKDRVHGMRFVFNKAATLGVFTKHSPSVAATHHRTLKRGSHGREVRAIAYSGHSGRRRRYIATGSEDTSIRIWEYTTAAGATSSPDENRGLRCVKVVKVHTAGLQSLKWLGEDLLFSCSGNEEFMVWRACDLGDRGLGLMREAVFADKSEDGDLRITSFDVVALDNEKNGNVAVTMAFSNSFVKTYRYTPGLGFELLFQGQYTGACLTQARHLRVREGVFDVITAATDGCLAVWRSQGSEYVLRHTERIHQSSIKALDVHFTTDDRVVVLTGGDDNALGIVTLVSDSSSSSSSSSDADNMNDGGFENWTRAGVRKAHAAAINGLTVLGERGGRIDFVTVSNDQRVKMWRLGWREGVEEITLLADEYSGVADAGDIEIIGDGKVAVGGVGLEVWDWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9CYL7</accession>
    <name>A0AAD9CYL7_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Forkhead domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_716865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000015">
        <property type="protein sequence ID" value="KAK1728828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060368883.1">
        <property type="nucleotide sequence ID" value="XM_060511886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9CYL7"/>
    <dbReference type="GeneID" id="85395784"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060962">
        <property type="term" value="P:regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="325"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="698"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="698"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="436"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="830"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="880"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="488"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="635"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="654"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="843"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="904"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="923"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1728828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1132" mass="121300" checksum="CD0E39952029C042" modified="2024-05-29" version="1">MTSSNAGQNGLAPLPTTPPPKHKSTTPGRTDHPDDNDNNNHIATNAADQQQPSRTDASTTVHPSIEDASTKEQSTSLAVDTFMVDADAGSAPPATMSQPASAVQVDADPFASSFPHTPMPNMDHAYMMMALAHMAGNQMSNQISPPPTVTPAQVTLPSTMGNGNDPLVASTHNLAAATQGLESFARIEFADSVFQMTTYAVIIGRDQKALNQARRDQKRDDAYRKKAEEYEREGLPPPSPVRHGPGKFSKSYVSEEGGMLGPESDSEGEGRPAKRRKTTSTGSSQKQEEDESQEKLISNRQYVSHTPGAAAVDLASLRPSPHHVPFVGIHSPGPDIASKTKAISREHLKIQFNKREGVFEAIPLHKNGFFIDEVHHKEGVAVLRSGDHLQIKDVDFRFVINGVPEGRTGAEEYAEEEEKLKKKATGGKEMSFEFEASHGNGLDDTSDSSLSSPAPSDVEMSDVEPEEEEEVEAESSSKAEAEAEAKAEAVAAAEKATAEAAADVAEAAQTQTEADDEADAEADAEVDVDADADAEADAEGEMSLDYGEEADDIQPTTEVKPEDQEMVHLLMGGAPLGYLNKKRGPGRPPKNGIMSKREQRLLKKAQQEMAKKTIPQPPPGEPPIKRKVGRPRKHPLPDEGGDRPEKRKYKPRKPKGEDGLEGSDAERRAREKKEKKARPKSPPLELKIEDYTEEQLQKPNKNYGVLIDETLTAAGPDGLTLKQIYKRITQRYPWFYFHTETKGWESSVRHNLIGNEAFKKDDTTGLWSRVPGVELDAGKKRKATSPDRSMSAGYGHYNHPMYTQYAQQQQSHMPPGYQHLPHNYHAQAYAGQQAQTAARTPQYSPPGVAPNPGQPAPPVTSQPVAPVTLPGYGAAAAIARPQGPSTYSSPPPPAHPAVKTEEGAAATSAPPITQPAPAAIPGAQPPPPQIPAAAPPQQARPTPTPPAQAEPRPVIQPRLLSAVNGLKNGLIENLKKAKNPKAEAIVMSALNRCLGLKSAATENQTMEDICMKGIQKLLDGFSTRSNTPGSGGTPTPTGPTNVFDSKVFNSLLGFKNVSSNALKSRIGEAKAEAVTLSAIDRVLGLADASIVPPPAEASASGSPAAGFDGIESHLMNSVKQLLLGLNQKLHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D017</accession>
    <name>A0AAD9D017_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acid phosphatase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_89250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000014">
        <property type="protein sequence ID" value="KAK1728966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369021.1">
        <property type="nucleotide sequence ID" value="XM_060515981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D017"/>
    <dbReference type="GeneID" id="85399879"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="379"/>
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            <end position="422"/>
        </location>
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        <location>
            <begin position="445"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
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        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
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            <end position="249"/>
        </location>
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        <location>
            <begin position="468"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1728966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="56761" checksum="897D211CAC327ACA" modified="2024-05-29" version="1">MKGLSGILADAYATWLSPLTNCCAPFSDSVEEKPRQNTFDISEKLSPPHTVTRNQPVPMPPPFAGTMQKSAGPRPQPQGKSKGVKRSFASLRERFSVRKRSRSDSSSRRLQISAPSNFRHLHSESFQFPQYSNLQHVGRTPPPRPMPRPRPSSFRPLELSIYVHKRELSPILPHFDMVTPPRPSAQVRPNPDDDVFGPSHEPNYSPMSFHLPRKMSASPSTLATMASDTPPKIPPKSRARSQTSSSASAERMKERIAGAMLEVDKLQREIELVMERQSIYASSRPSTAHSMALTAHEGILDLEPIPTVPALPPSAPSFAERLNPGAERPHTAPPRPPVHIPHRGMAFADASAAFITPPPSRGRENNRPPPPPPLPLVLRPPLRKKKSFSRVSSWLFPGGGNAAEQHNNNHHGRSISHDSITNFPRPVKGREGFYQCVHAPRDRRTSVDTASTVSTWQESDDDTGGGQTVPTTTWSPGSTLATRAEEQQPPLERVTTFGKEKDVGSPRRTGFAAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D169</accession>
    <name>A0AAD9D169_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat-containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_37228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000011">
        <property type="protein sequence ID" value="KAK1729596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060369651.1">
        <property type="nucleotide sequence ID" value="XM_060502644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D169"/>
    <dbReference type="GeneID" id="85386543"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050745">
        <property type="entry name" value="Multifunctional_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189:SF50">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24189">
        <property type="entry name" value="MYOTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1729596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="269" mass="29761" checksum="D0731FF2FD6EA020" modified="2024-05-29" version="1">MTDTVHVLLEHRAKPLLADDEGRTPLHWFCTLDTEFDEPHRKAFVALVDHGPDAVHMADLKGRKPIHLALEKYEDRSQMSTFAIRHLMAAGAEMSEPDPVTSNSALHTIAPRLVGEKTAAGDAATLFRDVAIAVDINTRNASGETPVFSFMAAGWKGTRDADYAIAHDVFHDTSLAMFIELGVDLTAVDAKGRTLLHAVADRNVRDTGVNWDQMEDVERSFQVLMELGVDPHKEDQDLKTAADVAVARQLRRVVDLFGEKDKIGEDDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D252</accession>
    <name>A0AAD9D252_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BDZ83DRAFT_746955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000004">
        <property type="protein sequence ID" value="KAK1731108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371163.1">
        <property type="nucleotide sequence ID" value="XM_060513349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D252"/>
    <dbReference type="GeneID" id="85397247"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12306">
        <property type="entry name" value="RRM_II_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF12">
        <property type="entry name" value="EUKARYOTIC INITIATION FACTOR 4B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="73"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="149"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAK1731108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="198" mass="21700" checksum="6A4C6CC34DF40DAB" modified="2024-05-29" version="1">MADVKPEDTPVEDHNVENNSVGEEDGHDEEEISAMKRRVAEMEEEAAKLREMQASLDQQSRELSENKEDIDSRSIFVGNVDYSASPEEIQAHFQSCGSINRVTILLDKFTGQPKGYAYVEFTEPSLVAQALVLNESVFKGRNLKVVPKRTNIPGMSRGRGRGGGRGGRGGFGGRGGFPPRGGYRGGYRGRGRGGYTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D362</accession>
    <name>A0AAD9D362_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="19">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BDZ83DRAFT_246381</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NADH-dependent reductase for DPH3 and cytochrome b5. Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1. By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex. The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>2 Fe(3+)-[Dph3] + NADH = 2 Fe(2+)-[Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71231"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:71232"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 19">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer. Component of the 2-(3-amino-3-carboxypropyl)histidine synthase complex composed of DPH1, DPH2, DPH3 and a NADH-dependent reductase, predominantly CBR1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="19"/>
    <dbReference type="EMBL" id="JAHMHS010000003">
        <property type="protein sequence ID" value="KAK1731335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371390.1">
        <property type="nucleotide sequence ID" value="XM_060501900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D362"/>
    <dbReference type="GeneID" id="85385799"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 18 19" id="KW-0274">FAD</keyword>
    <keyword evidence="5 18 19" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="59"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAK1731335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="308" mass="33931" checksum="21E81D98B91D8C0A" modified="2024-05-29" version="1">MSDLTTRKYFDNIYIPAGLIVFGCFITKREWTPYAVALALALAAYKFNAMQIKKVLKPDTFQDFELKEKTIISHNVAIYRFNLPSEKAILGLPIGQHISIGANCPQPDGTTKEIVRSYTPISGDHQPGYFDLLIKSYPTGNISKYMASMKVGQTLKVRGPKGAFVYTPNMVRHFGMIAGGTGITPMLQIVRAVIRGRPTGDKTEIDLIFANVTPQDILLKEDLDALAKEDSGFRVHYVLDKPPADWTGGVGYVTGDMITKLLPKAADDVKLLLCGPPPMVSGLKKTAETLGFKKARPVSKLEDQIFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD9D3F4</accession>
    <name>A0AAD9D3F4_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Beta-galactosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_564598</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 8"/>
    <dbReference type="EMBL" id="JAHMHS010000002">
        <property type="protein sequence ID" value="KAK1731456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060371511.1">
        <property type="nucleotide sequence ID" value="XM_060503660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD9D3F4"/>
    <dbReference type="GeneID" id="85387559"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.20.10:FF:000001">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000065">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000040">
        <property type="entry name" value="Beta-galactosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.20.10">
        <property type="entry name" value="Beta-galactosidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.390.10">
        <property type="entry name" value="Beta-galactosidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018954">
        <property type="entry name" value="Betagal_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037110">
        <property type="entry name" value="Betagal_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025972">
        <property type="entry name" value="BetaGal_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036833">
        <property type="entry name" value="BetaGal_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025300">
        <property type="entry name" value="BetaGal_jelly_roll_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13364">
        <property type="entry name" value="BetaGal_ABD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10435">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13363">
        <property type="entry name" value="BetaGal_dom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SMART" id="SM01029">
        <property type="entry name" value="BetaGal_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117100">
        <property type="entry name" value="Beta-galactosidase LacA, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041796" description="Beta-galactosidase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase" evidence="11">
        <location>
            <begin position="393"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1731456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1011" mass="109707" checksum="D77C809C553E3163" modified="2024-05-29" version="1">MRPSLFSIALLGLGLCSAAGVRSSLALAPAVKVLDEKRDQLQDIVTWDEHSLFVRGERVMIFSGEIHPFRLPVPSLYLDVFQKVKALGLNTVSFYVDWALLEGKAGDFTAEGVFDLQPFFDAATKAGIYLIARPGPYINAEVSGGGFPGWLARLKAKLRTSDPEFLSATDNYMANICGIIAKAQITNGGPVILFQPENEYTNFEDGSSADGPYFQYVIDQARKAGVVVPLISNDAKAAGHNAPGTGVGAVDIYGFDAYPLGFNCANPNTWPDNALPTTYHALHLQLSPSTPFTIPEFQGGSFDPYGGPGFEKCAALVNHEFERVFYKNNFGAGVTIYNIYMIFGGTNWGNLGHPGGYTSYDYGSAITEERSVSREKYSELKLEAQFLKVSPAYLTATPGNLTVGVYSATPDITVTPLLGNGNGSFFVIRHSNYNSLATTDYTLRLPTSQGTITIPQSRDLLQLTRRDSKVVVTDYPIGNTTLLYSTAEIFTWKQYKNQTVLVVYSGPGETHEIAVKSTATPVLVEGTSVDHNYVNNTLLLAWETSSTRRVVKVDNLVIYILDRNSAYNYWVPDKPGGSQTAYGTSIMNPDSLIINGGYLVRSISIQDGTLRVQADFNRTTEIEIIGVEPEVAKLEVNGKQLDHTTNNLTNWVANASLAGAAPTVSDLKSLNWTFIDSLPEIRAGYDDSAWPLADHKTTNNTIANLTTPVSLFASDYGFHTGTLVFRGYFVSNGTEDKLNITTQGGSAFASSVWLNDTFLGSFANGPDASGDNTSNYTLANLTAGATYVLTVLVDTTGLEENFVIPADVMKNPRGIMDYSITSPSGAETNVTTWKITGNLGGEDYADRVRGPLNEGGLFIERQGYHLPSPPESALNTQRSPFEGTETPGVTFYAAKLDLQIPATDLDVHLAFVFDDIAASNGTGAYRAILYVNGFQYGRYVSNIGPQTRFPVPEGILQYQGTNYIGLAVWALDNGGARVQNFRLEVGEVVTTGREEVKVVEAPAWSQRAGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U6R0</accession>
    <name>A0AAD8U6R0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_757851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000186">
        <property type="protein sequence ID" value="KAK1709162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060358501.1">
        <property type="nucleotide sequence ID" value="XM_060514952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U6R0"/>
    <dbReference type="GeneID" id="85398850"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085882" evidence="1">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1709162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="148" mass="15661" checksum="D2E60B042DFDFAB4" modified="2024-05-29" version="1">MAHFSRPVLLILTTLFLFYGFSTAFPSLAGALEPRCWRKACDHCERVTVTIDHPGSCNSVNRDNLKAAIDSTFVNYAGNCRGEEAGFSNQAIAGIQGIGCRVTVNFPRGNKGVDWGGLIGSNLVGTGSWAVSGTSTDGSVHCGGSCQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U762</accession>
    <name>A0AAD8U762_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_713660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a monocarboxylic acid amide + H2O = a monocarboxylate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12020"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35757"/>
            <dbReference type="ChEBI" id="CHEBI:83628"/>
            <dbReference type="EC" id="3.5.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAHMHS010000243">
        <property type="protein sequence ID" value="KAK1705334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357602.1">
        <property type="nucleotide sequence ID" value="XM_060511641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U762"/>
    <dbReference type="GeneID" id="85395539"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF4">
        <property type="entry name" value="AMIDASE C550.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="528"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1705334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1011" mass="112888" checksum="09B31D7AF0F1F19D" modified="2024-05-29" version="1">MGSLAPASWELKADKLRKILKDSLNPKWLLAPEDLPPSSQLNISKFIDTCKLLTPQEQEITACSGTELVSRMAAGKLTAVETVTAFLKRAHVAHQLTNFATEFLVDDALAAAANLDATFQVTGKIVGPLHGLPISIKEHIGLKGKIVHSAYVAWADNVAQEDALVLRLAAKAGAVFHVRTNVPQSCMHLDCSNPIYGTTVNPYNRNLTSGGSSGGEGACLGLRGSVLGLGTDIGGSVRGPAAFCGCYGLRTTALRNPYKGICLPGLGQESIKCILGPLANSISDIQLFEDVVLNQEPWDEETSLVPLPWKKMNPYQPGQFTIGVIWDDGMVHPHPPVIRGLKNAVDKLKAAGVKVVDFEPYKHSEGAEIIELLYFPDAAETQKEVLAEGGEPVAPLTEWAFHYSKPEPLTIRENWELNLRREAFREEYHKVMKDRGIDFILCPAYVGVAAKCGTPQYWHYTTIWNILDQPSITFPTGLHVDPTVDVVDADYKPRSATDEREYKKYIPEAFVDAPIALQLAAKLRTKTGCSTCKKRRVKCGEEKPVCRACVASGRGCTWPSSDDMYDRRHRCRRSFSDDRTLPSPSSWSEESIISLELRELPDLEQELTHHYLNVFLSVLLLTTVRERDLEGYGSQVMSMMLRSESVKCAVLAACASNKYMLLRARRYHDAALGYYFRAVELVNRALHDLGASTKGPGDPLLTTVVYLYLYDMWGPPDETLDARKHVDGAMNLLKLRYEDTYSPMSMSRPLHRINTESVLYQAFLLAMRKPFAPNFHVDEQFLDRSEHVLKARKLFDILSEGDSPVLGLPLPLYRLITDLIDVLNSPKHPTEAFLIRMREEMETWEGLVLVEDGEASCHSSMTSFHKDAVTLFVLGASLLLDYIAEFSFANHTSSPQVPRTTKDSLNPLHQTRSAPRWQVQRAFEILRRPAAYETWTRCFLGAWPMLILGYSVTSSGDISLIRRVLTQMIERMGYGEIQRILDDLEGVWTKRAEEIQRESVVMSAIERTCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U905</accession>
    <name>A0AAD8U905_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_253820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000306">
        <property type="protein sequence ID" value="KAK1702566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357155.1">
        <property type="nucleotide sequence ID" value="XM_060501951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U905"/>
    <dbReference type="GeneID" id="85385850"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1702566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="276" mass="30803" checksum="3709C8F04FB95033" modified="2024-05-29" version="1">MKRPDVCTSPGSRLPASRVGDIPNAQFNAKFPSLRTRVFMENHDSRLVDSNALNAPHTKETQQQIQCTASTFETIFGLPESLVSLISRTTHLINILGDALTELETPGIVDIIRTLEHDLCIWTFEGHATNAPHPRQDVGNQREAAFDNAREAVHAAVEIYFYREIRHVNPTSVQHLVEKALRHLLDYEKGVEERGNLAAAGVCWAAFIAGCEAEGISSRQQIAQFLSRIAQKSGTGNFRAASEFLPCVWESRMGLDKFDQSWREVMRSSNTCLILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U908</accession>
    <name>A0AAD8U908_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Emopamil binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BDZ83DRAFT_225304</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000266">
        <property type="protein sequence ID" value="KAK1704314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357421.1">
        <property type="nucleotide sequence ID" value="XM_060501766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U908"/>
    <dbReference type="GeneID" id="85385665"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000247">
        <property type="term" value="F:C-8 sterol isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047750">
        <property type="term" value="F:cholestenol delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004769">
        <property type="term" value="F:steroid Delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF0">
        <property type="entry name" value="3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="15">
        <location>
            <begin position="65"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAK1704314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="237" mass="26935" checksum="398FCD675FBEE817" modified="2024-05-29" version="1">MAAEIVMNATIPAHPYFPAQAVLPGYVANTFGAHALRGMFAAGATAILVPTYRIIKRTSPNLPNGEVATALWFTLSAFIHLFFEGYFSYNQSSMPASLHIFGQLWKEYSLSDSRYLTQDSFIVCMETITAFCWGPLSFACAYFIVNGHPLRHPLQIIISLGQLYGDVLYFATCSFDKLVAKMIYCRPEDFYFWCYYVFFNAFWIIIPFYLIIKSCAETKRVFAKVAELEKSSLKKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9G8</accession>
    <name>A0AAD8U9G8_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_658246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000262">
        <property type="protein sequence ID" value="KAK1704528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060357442.1">
        <property type="nucleotide sequence ID" value="XM_060511025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9G8"/>
    <dbReference type="GeneID" id="85394924"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1704528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="41101" checksum="20CFC053D00360AA" modified="2024-05-29" version="1">MAPILVATAPAQQQQQQQQVEGGPRPFQRTWDQKCPISDIMTTDVSPMLAWRKINPVIVPVTSPAPAPVGGSLLQAPQSPDLSAPGPSKIPGPSTMPEPSGTKATPGWPNQEACAAFEHASKQCTILDLGAETTCGFSLGSSCSSSSSLGCDSCSCGCPSHRTTSGRGSRQPDVEDEEGEREGKYGPNGKMLAEKTWKEHKRAETTAREGTVQDPKCGKCENGGYICVRKETGPCNICMRMSDVCSFTGQSNRKREVFRRGRMKVKSKKGATTVTDPPADPAIQQAKQKRGQEPSAQDGKDDDQLPDLPVSFGQQAGQPIVKDEVEGVGESGSHASGSSGLGLRSRTLSTSLPPVVRKRSDEVEEDAGEDSGPRAKRRRIAVNKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8U9J7</accession>
    <name>A0AAD8U9J7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_636574</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000130">
        <property type="protein sequence ID" value="KAK1714524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359986.1">
        <property type="nucleotide sequence ID" value="XM_060509263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8U9J7"/>
    <dbReference type="GeneID" id="85393162"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="652"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1714524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="729" mass="80688" checksum="D35EE5B0C45CC6C8" modified="2024-05-29" version="1">MSTSLPQRQPEGKKRQRVSIACLACRQRRMRCDGQQPICGSCTRRGTECEFQHADNKRRPPSKKYVESLQARIRHLEAQVVALGSQPASGDLAAETTEDHDPQDDSVGDDDDDGQGGPLSDLTGLVGRLNVTEDGQLHYFGSQSSYNLVRELPRDAPADPREPSLKMQRQGLVAAAQLGKMVTVPDELQAHLLELYWRWQNPWNYVIHKSAFLRSYRGEDDGTYCSPLLLCSIFAIAARYSDRPELRTVPDDPSTAGDAFGEHAKILLLYESEAPTITTVQAACLLALRIMSDGKEALGWLYSGNATRMAHNLGLHLDCSKWATAGLLTEEEAEARKVTWWGCYVVDKLFSTGLGRPSSTPKSTISCPKPSIDSNEEYTPWLPTSDTLGSEKSLGVHSHISSTACHVSETFTIACESMDIIYAANSKLSTREIEDVVSKTDVQLRTHYRELPSYLRLPASPKVPMLPHVCLFHIQYHAHLILLHRPLVHKRKRRSVSVNTPTDDGSIDGDGYDNQHMATCRHSAAEISRLLRIYKQQYTLRRIPIAAVHLCFSAVVIHLIDARPSNPNRQQAIRHLQTCVDALRDLRTAWCAWSDRALRAARLLAREWYQCEDVSLLQHWGGLSGVEGSMTGPTANAAAAAAAAAATGVTVGIPNTNDQQQQNQHQPYQQGGTADAERMMGQGQTTDGDVQGDPLAFLFDVATPDQYTDNLVKEWLAESGYDVLNTVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UAX2</accession>
    <name>A0AAD8UAX2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase family M3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_681749</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000140">
        <property type="protein sequence ID" value="KAK1713316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359642.1">
        <property type="nucleotide sequence ID" value="XM_060511215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UAX2"/>
    <dbReference type="GeneID" id="85395114"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000074">
        <property type="entry name" value="Metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="9">
        <location>
            <begin position="221"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="697"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1713316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="719" mass="82430" checksum="FB46A79C528903C5" modified="2024-05-29" version="1">MPRQPPQPLARFLAADEIVPTVQRVLATQRAARENAAATITPSEATFANTIASFLRADDETQGETGSFSVLRFSGPDKATAEAVEEGMRLWSASTAERLRMKGVYELVNAVRERDEKELGEEEKKIVKDLWLDYRGAGHGVLDEEGIRVYLERREIIEELKRAFRKNLYQGGGGLWLTEAELEGVPRAEMERWKVGRDEDVPEERSKRLVTLERADYDAVLRHARDPETRRRVYVAFDNRFPENVPLFKEMLVLRDENARMLGYGSHAEFRIERRVAPSTGWVEGFLGRLSKGLEPRGREEMTRIAERKRTDLGIVHEEKDSEEGRILPWDFEYYTRLLEEEADVDQEKISEYFPLNHTLSAMLGLFSEFLGLEFETVPDQDLVGKIWDKEVQVWAVWEGRGERKGEFVGYLYADVLWREGKYRTACNVNLQCGYLKEDGSRVYPATVLMCAFQPPTAASCALLKHREVVTLFHELGHGLHDLVSRTKHTRFHGSRVAPDFGEAPSTMLEKWCWMPDELVKMGRHYTRVNTAYMAKWREDHADGKEPPPETMPKELADRLVKSRELNRGLWFLRQLVFATFDMMVNNQESTEALREMDELKLYNDLQDSMTLRPNPDKRGYGLVHSTHLIELYDAGYYAYMSAQAFAASLFESCFAKDPRSPEAWDLYRRGILEYGGSRDEMEMMKEFLGREPGPDALLRSLGLSEGDGSDVGPTAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC46</accession>
    <name>A0AAD8UC46_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BDZ83DRAFT_590916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000161">
        <property type="protein sequence ID" value="KAK1711236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359039.1">
        <property type="nucleotide sequence ID" value="XM_060506379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC46"/>
    <dbReference type="GeneID" id="85390278"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16293">
        <property type="entry name" value="CPSF2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035639">
        <property type="entry name" value="CPSF2_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="6">
        <location>
            <begin position="287"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="611"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="833"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAK1711236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="972" mass="106365" checksum="EBF73452050CAF7A" modified="2024-05-29" version="1">MFTFCPLQGALSDSTASQSILELDGGVKILIDLGWDESFDVEKLRELEKQVPTLSIILLTHATTSHLAAFAHCCKNFPLFTRIPVYATRPVIDLGRTLTQDLYASTPLAATKIPHGSLTEAAYSFSQQPTADSEFLLQAPTPEEITRYFSLIQPLKYSQPHEPLPSPFSPPLNGLMITAYNAGHTLGGTIWHIQHGLESIVYAVDWNQAKENVFAGAAWLGGAGGGGAEVIEQLRKPTALVCSSRGAEKVAQAGGRAKRDEQLVDMIKSCVSRGGTALIPVDSSARVLETAYMLEQAWRVDSQTDGGSLKAAKLYLAGRNMSSTLRYARSMLEWMDDNIVREFESVADGQRRTNGAEGKSKEGVPFDFRYLKLVERRAQIEKLLSGSADNVQAEGRVILASDDTLEWGFSKDLIQGLAKDSRNLVILTDKPAKSQTERPSIARTLWDWWTERRDGASVEESSNGNSLELVYGGGRELEIQEAKRQALEGDELNVYQQWLATQRQLQATLQSGGGASLQAPADAADDVSSESSSDSGESDNEQQGKALNISTTMGQATRKKVVLTDEDLGINILTKKRGAYDFDVRGKKGRERSFPLVMRRRRDDQFGDVIRPEDYLRAEEKEEDTPDNEGLRRDDDDDRLGKKRKWDDGNNKAANKRQNNRAGSVDDLDANGPGDHVADEFDDVEDVAEEEIQGPSKLIVSTEKVMVNLRIAFVDFSGLHDKRSLNMLIPLIQPRKLILVGGTADETTALAADCKKLLAAQIGASEESAIDVYTPAMGAWVDASVDTNAWVVKLADSLVKKLKWQNVRGLGVVTVTGQLIAEALAKEKLVEKDDGANKRQKTEAEDAEAGEEVKKEEDEEDETTEIEVVPTLDLLPSNMASAVRSVAQPLHVGDLRLTDLRRAMQSAGYTAEFRGEGTLVINGAVAVRKTSTGKVEVESVGIADAATMMQHRSTFYEVKRMIYDGLAVVAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UC55</accession>
    <name>A0AAD8UC55_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BDZ83DRAFT_757334</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000160">
        <property type="protein sequence ID" value="KAK1711251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359054.1">
        <property type="nucleotide sequence ID" value="XM_060514883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UC55"/>
    <dbReference type="GeneID" id="85398781"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12163">
        <property type="entry name" value="2-Hacid_dh_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333">
        <property type="entry name" value="2-HACID_DH_C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43333:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE NAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="128"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="3">
        <location>
            <begin position="233"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAK1711251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="363" mass="40702" checksum="E09174F7AE8F8D32" modified="2024-05-29" version="1">MGDLGNRQSPLAGDKLLVFLSAPEDTKWTSRISERFPGLKVCWESNLRPGGGFLLPDELPDEVWEDVTIFMAFNPPSAHRLSKVRFVQLTSAGADRWLDHDVYKDPNVSFCTTNGCHPPQIAEWVIGSWLAHQHHFQRYHNHMKEGFWEGPMEVDFEDSVGLRMGVLGYGAIGRQCGKVAQAMGMEVYAYTRSERATPESRKDDSYCVPGTGDPDGLVPTKWFHGASKEAINNFLSQDLDLLVLGLPLTEETKGLIGKEQFEILSKRKTFVSNVARGPLIQTDALMEALEDGKIRAAALDVTDPEPLPKDHPLWKAPNVFITPHVSWRTDGYWERVLGVLEANLERIDAGKPLINVVNKKLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UCU0</accession>
    <name>A0AAD8UCU0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED8</name>
        <name evidence="11" type="ORF">BDZ83DRAFT_756109</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000117">
        <property type="protein sequence ID" value="KAK1716099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UCU0"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074:SF9">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="203"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1716099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="293" mass="32067" checksum="62B12D37B3CDDD9F" modified="2024-05-29" version="1">MDKPNALGITADEFKAIEQTRQRLFQLSNSIQGLRMDVLKSNPLPPPASLQAQSQILLRNLQSLLETLTENTHVFQHLHVFPDVAYPGRVHENILLQLLRKKLEPGVEEWVERGRETTRELRGTNAPLSLSDGSSVGIGGGPGIAGGPVAAGNGGGGGGEAQLEAVWRDVRAWTVERVQKYVLEEAGDVYTEDERRMGVDNVRTGLKRGLEEDDEDDDDEDEDEESDEEGGGGGGDGDVVMSGQSQPQSQKTKKPTKPTGPEPEMLFWFEARGDFDLPRNVDLLSQAGMKRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDQ0</accession>
    <name>A0AAD8UDQ0_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GMC oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BDZ83DRAFT_723250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000131">
        <property type="protein sequence ID" value="KAK1714109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060359925.1">
        <property type="nucleotide sequence ID" value="XM_060512544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDQ0"/>
    <dbReference type="GeneID" id="85396442"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF123">
        <property type="entry name" value="GMC OXIDOREDUCTASE (AFU_ORTHOLOGUE AFUA_2G01770)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="5">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1714109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="495" mass="53059" checksum="FE00EEC8AD88910E" modified="2024-05-29" version="1">MTLWDCIVVGGGIAGSVVASTGPNLKILLVEAGTNTHAVENIEWIDMNNAIGGEYDWGFSCVPQTHLDNREIVSPVGKGLGGGTIINGAAWARGHKVDYDIWAERVGDPRWSYEGQLPYMKKTESLFDNFTNPLSHGHTGPVKVQSPGSTDHVFPLREPLLESWKELGIDALPQLDNNAGDNVGVADLQENRDQGKRQLASLVYSLKGITGLTDSLVAKVLVEKHPKDGHLVARGVRLENGTEILGRKTILSAGAYRTPQILMLSGIGSAETLKKFDIPILLDQPAIGQNFHDHVLIPTIWQLKDASARYAKESGNPIVNQSHHAIGAFIDFITVTSLEKEGLVVAIAEDEGSVPDPTVHPLLKQDRAHSSHLLQYSGVSADGSAVLMISVVFIILSEGREVVAGELAAEPLTVNSTDEQIDARVREMAAGCYHPAGTASMVTVVDTDLRVIGVSDLRVVNTSVFPVSVSANLQVAAYALAEQAAEIIGSTMKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UDX2</accession>
    <name>A0AAD8UDX2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_636497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000129">
        <property type="protein sequence ID" value="KAK1714568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360030.1">
        <property type="nucleotide sequence ID" value="XM_060509257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UDX2"/>
    <dbReference type="GeneID" id="85393156"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1714568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="62" mass="7299" checksum="5071148DA151F6FE" modified="2024-05-29" version="1">MAPSVDFLCWIFPVHTSRSRPVKSVVIPKKAIRISFTICLGLLKEWRSHQKSRQRYQKTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UE28</accession>
    <name>A0AAD8UE28_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Cutinase</fullName>
            <ecNumber evidence="3 13">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_585894</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cutinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 13"/>
    <dbReference type="EMBL" id="JAHMHS010000101">
        <property type="protein sequence ID" value="KAK1718743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361243.1">
        <property type="nucleotide sequence ID" value="XM_060505888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UE28"/>
    <dbReference type="GeneID" id="85389787"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000235">
        <property type="entry name" value="Cutinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF3">
        <property type="entry name" value="CUTINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 13" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042218085" description="Cutinase" evidence="14">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="57"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="194"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1718743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="238" mass="24971" checksum="20A51CD7665958FB" modified="2024-05-29" version="1">MKFSAVLALASIAAAFPTLSEPELDERDILEIEARDIEARQRGRVGSTAKEFSTGGCKDVVMVFARGSTEVGNMGTICGPQTANNVKGQFSSVAVEGVDYAAGLSTNFLPGGADPAGVAEMKKIIGEVNSQCPNSMLVVGGYSQGAAVTHRAVEDLPQAQKDQIVAAFMFGDTQNTQDKAQIPNFPKSKTKIICAQGDAVCKGTLTILPAHLSYGNQAGNMADFINQKLTAAGAQRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF15</accession>
    <name>A0AAD8UF15_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED11</name>
        <name evidence="6" type="ORF">BDZ83DRAFT_635417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000120">
        <property type="protein sequence ID" value="KAK1715564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF15"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019404">
        <property type="entry name" value="Mediator_Med11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10280">
        <property type="entry name" value="Med11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAK1715564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="197" mass="21527" checksum="5A99E30950FB96EE" modified="2024-05-29" version="1">MADTTMTTDAPPNEPFTLQERIQQLCEIDTQIVSLMSHTSSALSALGAAPKPSPPSDPSNPSVPPPPSSSSQTQTFKTSMDALLSTLHTVDVHMKRQILALEEASIIKLRNDADPKTRQPVMNEDAKIVARPSLEPNGVGTIGNLDVGWLNSRNNKVERDMEAELWAKMRELLERYHAKEVAEGAGGSGIKDERMQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF29</accession>
    <name>A0AAD8UF29_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_653709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362806.1">
        <property type="nucleotide sequence ID" value="XM_060510636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF29"/>
    <dbReference type="GeneID" id="85394535"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1722751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="350" mass="39630" checksum="FD3A5C35FAFF27BF" modified="2024-05-29" version="1">MVQWRGGPNEIKSDVSRLETSMAAKPYTSARSHKDEVTSPTRRQNQGGPANESSVENYFEIPYDADEPRAARSPEMVEEGYIEQEMTQRERDVAEACTFLEGFIMERWETQLQAGYIKIVCNLTLDEIRELGRLRMAEGTRECRKLITAPVLHDAIGHALWLEMANEIGRHEMTTQFANTSLTAVTEKEETPRPSVIKWSIEKEVAERRARSMRRRATEGDVFTEPTSSLNRSVPPTADRTRRKSEMSTLRPNQIMCTTCGSRAMPDYKPDEEQSQTDEDENYDVDMSAPQENGDVELQEATNCMERQVKKRSSISRRLSLKVNQTLTKFGEGLAPGYMYGGGAGGRVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UF50</accession>
    <name>A0AAD8UF50_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_635370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000119">
        <property type="protein sequence ID" value="KAK1716029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360423.1">
        <property type="nucleotide sequence ID" value="XM_060509170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UF50"/>
    <dbReference type="GeneID" id="85393069"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1716029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="270" mass="31073" checksum="A710FD1FCA8ACE08" modified="2024-05-29" version="1">MVMLRQKEDRDAAGKRSRFFLRGQEINWERVVQYLKHRPDLQDTSSVDIARYRDTSSDITCSTPSPTLFKNEIPRRITPHSDLRLLDDSIRLIHSYLDGAFETGLVVIEGHILYGPNGEPARQRVRKWHEDMADIHVLLSSKETTAAFRLLNKQLDLLKHLIREQDPELLLLTFHDIFDLEPNLAESLLVFVCRMHQAIFGEHHPLSLIWDNFVRFTAKARLQAVLRMAASTAKEMEARMGAQSVYVEALECLQVDVHKQRGSKDAFGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG11</accession>
    <name>A0AAD8UG11_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7357 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_586811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000109">
        <property type="protein sequence ID" value="KAK1717359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360846.1">
        <property type="nucleotide sequence ID" value="XM_060505982.1"/>
    </dbReference>
    <dbReference type="GeneID" id="85389881"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055781">
        <property type="entry name" value="DUF7357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24054">
        <property type="entry name" value="DUF7357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7357" evidence="2">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="799"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="743"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1108"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1302"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1392"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1466"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1535"/>
            <end position="1544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1717359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="1544" mass="168060" checksum="2FEE3EF81C1EEAE9" modified="2024-05-29" version="1">MEKDLRLRLVVRRHAVPDVKLLWNVTANDDLTISKLLALVNDVVPLESGEWGLEDYAVELKDASGDGFECVHYHLVSKVLKDDDQVIIRPLLTGDLKRRRLSGRHQITADGKHLVDGLAFGRPWLRAPRDRPIVSLPPRKKARITYISEDEEDSPSEAEAERPMLEYESTRAQEDPSSVQLRTRFYNADIGSDSEADEDDFEPVAADDDDEGMDSDNNDIQDELRMLREDNAAVREGDILEELRNIRDRRASSGTASSRRSLETSDDSPVPSASNALVRSAGRSNRFHLNLDTLDKIAALRAAFPSAQVSTIERVLLRYGANFARVYRKLNKTFESRLSLQQTLDHQARSLSSSPIRHANSNMGRELVLRESSPLDRSSHPTSNGQDEEEEEDDSDEASETINHNAQADRASIGSDEISTSDFESSSDGATSESDEEMGIASENDTVASSSDDESDSESSEAGGDGPVMDEDNSDSADEEASSSDDDSSSDNSSSDESSMASAKDQLYAKQVAIVEVSSDSSSGSSSDDSSSEDSSSDSEPEELPSKTLSSQRILFESNKTPEPTQAAPVAAAQTKQQQPDVPPGQGLSKTQKRNARRKLAKKMAGQKGSPAAQNGEGLSPAEVSEMQAAFLARKQALLNAITSDGPAEASQEKALEIPDSAPQDVETSIADADMVEASQSPAAQEAASQRRMKPNVGAARRMLMGSLGLKNPKNKADEDKIRQGLMKGVRPHTNARLSGGASQPSESTQTQESVEEDPEAWREKIAYRAVECCHDGVELSEPPFPFVQRWDPQQQVEEWFGSKNKRGGKRKRVQRDQAQYHEDAESQSSKKRRVTDDSFGVTFSDAVESAQEGDTILNYDDPSDDPPATKKPAEESQATDIDDLPSLPSDLSTLPDLRPGEARLGMVVTWKQLVLSSQTNWQPQVVSLTGVLVRIYDEDASDLEFILAHRDRGVDRTEKTYDEETGERVYDRFEAPDDDEDDEDVENELEEGHRRVNYLELIEPKIVQFPLEDDTKQGENEKSGASEGESGPTDSVIHETVYDGQSQPSQVNGEISGQSEVGEVGSQSKVDAKGSRARANTGEQQPQVVAGSDPHLDASADVDESSQLDTHLSGNDDNMDESDVPTPRAKRQSKDDNTVPTTEDDSQNSNGNALSISSDRRHEISIMVEEAGFRKDVSPSVIRHKTSSPSRQLLDQLQAANAPRVISKSPLSQDSVARNVAPAPDNSGYAATKLNAEDAIPPPSSVSSIRSGRQLDPDDFSFNMGGDDTQLMSDAGHGSPSVDASTPRAQVRTPTRDNDTPEPNSGEKSSLPSLESLFKTASQRNSQKNTQSPSKSPILSVTESRKSLVSRDEEYEAAMRQIDEANEDGENGVEEDESPNEFGKIRRELFPNSSQPEGVTLSESPDLPDLKPAKSVPSSLVEVEDIKPRRLRERVRTASPFVVPAGSLVVTLSSSPPSSPLGENYAEDDVDEDYEENNSSSLPRGSGWVQKSKPPKANPRAKSVPAARSTAKTATAGRSVPSSSMPARSAAKGKGPRKSSARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UG20</accession>
    <name>A0AAD8UG20_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BDZ83DRAFT_587224</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CBS 112980</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="JAHMHS010000113">
        <property type="protein sequence ID" value="KAK1716749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360679.1">
        <property type="nucleotide sequence ID" value="XM_060506017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UG20"/>
    <dbReference type="GeneID" id="85389916"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAK1716749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="238" mass="26490" checksum="0ED16CB48791F2B4" modified="2024-05-29" version="1">MAANKYSVILPTYNERRNLPIVAWLLNRTFTQHKLEWELIIVDDGSPDGTQEVANQLVKAYAPHVILKTRTGKLGLGTAYVHGLQFVTGNFVIIMDADFSHHPKFIPQMVARQKEGNYDIVTGTRYAGNGGVYGWDLKRKFVSRGANLFADTVLRPGVSDLTGSFRLYKKSVLDKVISSTESKGYTFQMEMMVRAKAMGCSVAEVPITFVDRVYGDSKLGGDEIVEYAKGVLSLWAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH39</accession>
    <name>A0AAD8UH39_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_461140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361544.1">
        <property type="nucleotide sequence ID" value="XM_060503236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH39"/>
    <dbReference type="GeneID" id="85387135"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="235" mass="26026" checksum="F7A97449D825D6E7" modified="2024-05-29" version="1">MAVEHETNQIGRGKGEVYEGNADREDRNRRARTKGSCQGRQADPVMHGKPIGCTWLTMENYTQEKEGEMRVQGRLSIKLVYPTLPPSRRTTDADLGKDRIWQAILAATPVTSCTRFGGGMEAIWLFGRASIRTKSYGRPAGTSETFPVVVESTPLYSYGVLLSGRAENEVPGAGTNPYSAEERASSRNRSRNEVDLDETPSPATVTWGRREPQQWDVTLLSTVAPRHMRTPQAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UH96</accession>
    <name>A0AAD8UH96_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_582086</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000073">
        <property type="protein sequence ID" value="KAK1722827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362882.1">
        <property type="nucleotide sequence ID" value="XM_060505521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UH96"/>
    <dbReference type="GeneID" id="85389420"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF10">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="41"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="548" mass="61410" checksum="20B2A4ED28531409" modified="2024-05-29" version="1" fragment="single">PWKVNESQRSQFIQYLKPYAAALGSFKLPSRLSLSRYIAGYIDGYNDHHPFMHMPTFCMKYHRESPELVLALLAVGAQLRYETRNASALYRAGRAIILHRLESGELATQPGGLCGISRPSNSLALAGVEAYSSAAASRLDTMKAILLLATYSTWQEDLCLVRESLEYPGLLARCLRESGLVNDASYNDKDLDWHSWARAESDRRAKLAAFCFLNLQTLVFNVPPVILANEIDLWLPGTCDEWLAPTAALWLRARSKSPALVRFQEAFVNLVQPRTEECPVPSPFGNFVLIHAILQRLIVAKQLSLDPASPGYAPEEVAKFESSLHRWRDQWCKAPESVLDVRHTKGSLSWTATSLLGLAHVRLHFASRRPQEVCSGNPKIIAGNAWNARPPERGPHLVYALLHAVHALNIPVQLGIDYLASCQAFFWSLQHCFCSFEAAIFLSKWLFMLAETQGTEELDVNERQIIRWTECIVNEALASLEAIDGYDLSTTEDNTSHSLEALGNLVIKLFAKMFERCNSAWPIMRTIGQSLHEYSSLLGKCDKSPSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHK4</accession>
    <name>A0AAD8UHK4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_654532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000091">
        <property type="protein sequence ID" value="KAK1720232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361743.1">
        <property type="nucleotide sequence ID" value="XM_060510726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHK4"/>
    <dbReference type="GeneID" id="85394625"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="272" mass="30011" checksum="94189596385D8809" modified="2024-05-29" version="1">MIVGTTRRAPSSGILQQVGRTKTGEAAIDPDPTENGLWDGGGTYRARRWLGWLAKTTSRFGVWAGMALATQPRPDLVIKSGISSTVDFEASFCVPDRFAKLLLMNVGMFAGYEVVFRVDEATCPRFSATAKVVVHLLLTQRGNKHISVTGPNPRLMFYLSERCRWTGADKVRASEVCHPRDNKANVRQRAWMSWLSGTGGSSGPKSNRGFENQNLFLRGEKFKAHRAPEACGLRMRLELCTVASSSYDIGRTWSGQVVLRAPRRSSNVSRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHQ1</accession>
    <name>A0AAD8UHQ1_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Carrier protein YMC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BDZ83DRAFT_755735</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000107">
        <property type="protein sequence ID" value="KAK1717448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060360935.1">
        <property type="nucleotide sequence ID" value="XM_060514660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHQ1"/>
    <dbReference type="GeneID" id="85398558"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="109"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="212"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAK1717448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="301" mass="32632" checksum="AB6996CF19AB7058" modified="2024-05-29" version="1">MADAAVEPEVVGGALQTAKDLFSGAAGGVAQVLLGQPFDIVKVRLQTSTTPTTALNAATQIYKNEGALAFYKGTLTPLLGIGACVSIQFAGFHQARRFFESRNGSTGPLSYAQYYASGAFAGVANSVISGPIEHVRIRLQTQPHGAARLYSGPLDCVRKLASHGGLLNNGLYRGEAVTILREAQAYGVWFLAFEWMMNADARRNNMDRKDIAPYKIAFYGGLAGEALWLSSYPFDVIKSKMQTDGFGKEQRYKSMRDCFAQTYRGEGLRGFWRGIVPTLLRAMPVSAGTFATVELTMRAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UHR6</accession>
    <name>A0AAD8UHR6_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal-specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_627305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000070">
        <property type="protein sequence ID" value="KAK1723067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060363122.1">
        <property type="nucleotide sequence ID" value="XM_060508621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UHR6"/>
    <dbReference type="GeneID" id="85392520"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1723067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="289" mass="32293" checksum="05A61867A567DBA1" modified="2024-05-29" version="1">MASTLMMCFFEILHDCSDSWKVHASFGKSFLRHELASGHTMLSGSEELYGFAAAYFAYHDALASTAGTNVVMQDNNSSLCHLLDGEESVLESLSGCSRHQIALLSEIPDLTSQSSCQDGILERSASWNQKRDAIERKLHLMKDTSVPSSSELSSKSAKDEAPWLVPELKRLTCLLYFHARVDESNPSDPHIIRLTEKILELLPHVSLQTNTVLWPLFIVATLGVRSESDSDRKFILERLHLLQQTRQLGNVRKARQIIETVWKARDIGSCGGKQGWVILEGRHDAMSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UI45</accession>
    <name>A0AAD8UI45_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activator protein for ras-like GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_584311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361941.1">
        <property type="nucleotide sequence ID" value="XM_060505745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UI45"/>
    <dbReference type="GeneID" id="85389644"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="185"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1720430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="779" mass="89117" checksum="49D8DE73FD092165" modified="2024-05-29" version="1">MSVMLQTPSRASTASSSSFQPLSRQNTMSSYDGSRSARQSKRYSMSALYMSMSANETDLEIEDDLAKAQKILRELKSKISSQSKKNFVLEKDVRYLDSRIALLIQNRMALEEQNEVASHLEDATDMQEGAFPNDDKTQKYGNLMFLLQSEPRHIAHLCRLVSMSEIDSLLQTVMFTIYGNQYESREEHLLLTMFQSVLTYQFDNTPEYSSLLRANTPVSRMMTTYTRRGPGQSFLKSVLADRINSLIELKDLDLEINPLKVYERMIEQIEEDTGSLPASLPKGVTAEQAAENPQVQAIIEPRLTMLTEIANGFLTTIIDGLDEAPYGIRWICKQIRSLTKRKYPDANDQVICTLIGGFFFLRFINPAIVTPKSYMLIDGQPADRPRRTLTLIAKMLQNLANKPSYAKEPYMAKLQPFIYQNKERINKFMLDLCEVGDFYESLEMDNYVALSKKDLELSITLNEIYAMHGLIEKHNGELCKDDNSHLGIIMSELGGAPPQVPRKENRAINLPLFSRWETAIDDLTAALDITQEEVYFMEAKSVFVQIMRSIPSNSSVARRPLRLERIADAAATSRNDAVMVRKGIRAMELLSQLQELKVIDKSDQFGLLRDEVEQELQHLGSLKDGVIQETGKLEEVYKTIRDHNNYLVGQLETYKSYLHNVRSQSEGTKRKQQKQQVLGPYKFTHQQLEKEGVIQKSNVPDNRRANIYFNFTSPLPGTFVISLHYKGRNRGLLELDLKLDDLLEMQKDGQDDLDLEYVQFNVTKVLTLLNKRFARKKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIY4</accession>
    <name>A0AAD8UIY4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_653812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000077">
        <property type="protein sequence ID" value="KAK1722584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362639.1">
        <property type="nucleotide sequence ID" value="XM_060510652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIY4"/>
    <dbReference type="GeneID" id="85394551"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1722584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="182" mass="20005" checksum="D797FD7A773ED1D5" modified="2024-05-29" version="1">MLGRIAQAAQLPKFNRKFKNIGESPGLLFLSKDIVREYDGVPSLTRSSVREASETSSFDPTISATVWSYTSPSYSPSPASAKSSWPNSVGSSFRLTMLRLDVTGAIGYLNIPYSSSSVGNLDHDRLLTEKFPKNLTKLPHVGQGRGCVTASVLYGSYVDRRKALALQKAWTLECSMRSLYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UIY7</accession>
    <name>A0AAD8UIY7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PHD-finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BDZ83DRAFT_784066</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000080">
        <property type="protein sequence ID" value="KAK1722393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362448.1">
        <property type="nucleotide sequence ID" value="XM_060515603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UIY7"/>
    <dbReference type="GeneID" id="85399501"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="677"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAK1722393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="756" mass="80775" checksum="EEB19E0F86526C5D" modified="2024-05-29" version="1" fragment="single">RNSDYSFGNPNAQPPTPKQTPTSAVFPSPVFETPKQSQGHFDDAGGWTPRFAEEYSVFNTTPGNLRGSPGSFPDFATGATTFPASASLKRPLSAESLAAQIATHANHFSPNTNLPLPPVTAARRLPSSPRPPIEQADFSSQEGGSASPEQASQDSTAKSSQGRESVADLNGQTATPPPSSHKGGRKLAPKLQDDNMQNDHGYGQPDFSGNPQHPNMAAFVTATDMFGYPMSAPATASASFWDPSADMSGMEIDFSFGPNVFQTSGHRHMPSFDASQMFQEPAALPPSGSQETAQPIKRTRPLAPKPVMNNVQSSSADISMVTNSFSTSMEDPFGIMSPGGVDPGVLFGRPLSANMGANIPVTQGSAQFALAAAAESQSRAPMHGDIRRSLSTKELGHGRPSGHASINSPIKANGRLNGLQRSASENRGRRGLSKPSLPKLAPAIQPRPQVANGPVAGPSRPPSRPSGRLSPLKQQHSRLSSLTSIPESTPPRPRTAVKFTIDSRGRARAETTMVMDEPRLEEVRRLPVTREMPRREKSWESEDDDSSTDDEPIIIPSRNTSFALPDPRRPSSASMFHSSRRSVSEHSSSSLGASVSQHEAESEAETVMNEAQGKGGDAASELRKLVESRQKRGHQAPGSQRSQRFASGSFQGHLGGMMSPTGFTEASLPSPTKATYNVRCVCRNSTDRQGEYMVQCESCEMWLHGSCINISKRTLPSVYICAFCSNTPNMRGGRLRGNGPALGPPGASPLARKSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJ92</accession>
    <name>A0AAD8UJ92_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_722097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000095">
        <property type="protein sequence ID" value="KAK1719451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361535.1">
        <property type="nucleotide sequence ID" value="XM_060512438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJ92"/>
    <dbReference type="GeneID" id="85396336"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1719451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="358" mass="39587" checksum="FEC7DCB5DA0B69EF" modified="2024-05-29" version="1">MSTPLLPVYFELSWSILSTIGAANVILGFLIVGITTFSQINAVPIISSAAGAIANGLCYYAFYDETYSLKSKAAASVFGDIFWMIQEVGLSFYSYVLLRRILKDLGWKIFNSLFWIMVLSIISIRIMIAVSRAKFILRGNTNLQSTVNNLHIGYFVLIASLECISSFFLLKTFAEVKSTSLRAALKGGLFKYLMRSTEVRLATLALVGTMRAVTYSFQIAAQSATNAASQIDRFAYTLECLFPVVMFIDILASKLVFTTQVYHPTQPSRPPLRGFASYQKQNDWYAATQHSERLVEVRGGRRASSQENIISAGSSRSNIGLDGIEPTMLVGINKTVEISVLHSMPARPDTQAHFLTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UJS4</accession>
    <name>A0AAD8UJS4_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_628227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362751.1">
        <property type="nucleotide sequence ID" value="XM_060508681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UJS4"/>
    <dbReference type="GeneID" id="85392580"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.490">
        <property type="entry name" value="GxGYxYP glycoside hydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025832">
        <property type="entry name" value="GxGYxYP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038410">
        <property type="entry name" value="GxGYxYP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048309">
        <property type="entry name" value="GxGYxYP_N_3rd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37321:SF1">
        <property type="entry name" value="EXPORTED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37321">
        <property type="entry name" value="EXPORTED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14323">
        <property type="entry name" value="GxGYxYP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20958">
        <property type="entry name" value="GxGYxYP_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GxGYxYP putative glycoside hydrolase third N-terminal" evidence="2">
        <location>
            <begin position="42"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GxGYxYP putative glycoside hydrolase C-terminal" evidence="1">
        <location>
            <begin position="146"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1722696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="382" mass="42740" checksum="4899E64FE179641A" modified="2024-05-29" version="1">MIYKFDVPPQTTQLTLTLSMWNQFLVSASSARPGYYRINSIFRDYIVSTAAPCIWLDSNRQREAALLDKLLRQFQPNTAYLGWFPNGDEMTGVTQLARNGLYVAAADFYFNPTIFSGFSTKSQSQQSAIGGPPWRPPPPPPQKTPKVFLSLVYLEGDNIQYDQRSMFQHWNDSARGSVPLGWTISPLLRDIGPGILSYYQRTSTENDLLIAGPDGAGYTYPGVWPRRALSTFLTQSGEYMRATQTDEVLFVYDRINASDNPLTPGLTLDFRDAVGRNRLRGIYYGSFVSTVDALQVNVTEGFPVTNMVSIGNEESGAATLRNISDNWRGRGPLFVAGAVSAFDMTPTSVTSMVKKLGHEFEVVRPDMWFELLRKRESWPGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK11</accession>
    <name>A0AAD8UK11_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_784906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000088">
        <property type="protein sequence ID" value="KAK1720444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060361955.1">
        <property type="nucleotide sequence ID" value="XM_060515617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK11"/>
    <dbReference type="GeneID" id="85399515"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1720444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="241" mass="26506" checksum="C5A58BAB36CDB4BD" modified="2024-05-29" version="1">MDMKHAHAGPGPRISLFLSKAPGSKATNGALQRRPLHLNTPCQINVRSHPQEEEEEENFSVVLHLSGTKQNYQSHSLSCEAHSDWLPVSSVRHLPFGDGNKATLKGRTLTKVYPPMFHALVHVCVFDHETHSTDFATSSVRQDCLSSARPQTTAGVCDVNRKAGNYWDPQLPIFGDFWVSIRSLTAGSLWFNVGNVIPTLMRIHRTATNPLGLSLQDPLEVDSVVGAWMPSLFVSCAAVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UK37</accession>
    <name>A0AAD8UK37_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER transporter 6TM N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BDZ83DRAFT_703505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362764.1">
        <property type="nucleotide sequence ID" value="XM_060511479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UK37"/>
    <dbReference type="GeneID" id="85395377"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994">
        <property type="entry name" value="ARAE_2_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994:SF4">
        <property type="entry name" value="ER TRANSPORTER 6TM N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="727"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="766"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="7">
        <location>
            <begin position="55"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="7">
        <location>
            <begin position="154"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="8">
        <location>
            <begin position="649"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1001"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAK1722709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123808" checksum="27E82A893FCD7FA2" modified="2024-05-29" version="1">MASDEQKPDADRYTESQSPETETHPDGAPARSPTTASKATKKPAPKPGLAARLGLDAPTLIMMFKGSLPPLIGIAIYQSTPVAQYFTTLGYLVPIISVLALAILPRGKYLQNLVLNVTGICIGGALSMLALWSGVQARRNTASAEELATGLPVYNSSQSAVCGVWLFFNIWISNTLRAKYPAMNLPVMIYSIFMNVACTFGPLMVTTAAAESLVKRLTVAMLCAMGIATGVSLFVFPVSSRKVVSGEFKGAIGLVRKSIVLQLNYLKTLSSPDMLERHQTKSSNVFKKNKKQKKPEVTKEAKAAGELKATALAISALFGKMHGDILFAKRDIAYGKLNSKDIGEIFNRLRSIMIPLNGISTIVDIFRRASEKHGWGVNDGNGDSDAEKEREKRVWNDIMLQLLEPFEILTEAMDQGLDHVGIVLELTPKPKKTKGTDVEMDAGAKATSKPGEAGFAEVLAERVQDFNDKKGELLRNWLKERQLATEQERQDLHLKKLETRMRERDQTQLYVMLYMEKLMLALGEAVQDLVMFADSKVADGTMAKKRLIIPSQKRLKKWFKGICSTEDASPEQTPDIAEMGANIVYAGDGYNKKKDPEHLPAHGVWQHFGNSVRAFSGFVGSGESLFGFRVAIATMTVGIMAFLQSTQTFFTEQRLVWAMIMIAIGMTITAGQSIFGFVCRVGGTCVAVIFSYIIWYIVVERTAGVIVFLWLFIFIEQYFVLKYPRFMPVWLITIITQVLIIGYELQVQKIGEKAAAATGQPYYPTYLLAPYRLACVAAGCFIAFIWTIFPAPITDRRWLRRDLSASLYLLANYFSVVTETIKATMEETHGDIKKPGTPAHKMEKERRRILGKLLLLLPSLDQHAQWQKWEPDIGGKFPRATYEDIIRRSTSTMRYLTLIAYTITWKPRDRPASPSSDSDRAWLRALNQVLAGIEPTQHTILSTLTLLSNSLLSGQSLPPFMQLPRPNELTRKLLHLKGPEPEPRTMQRRGSELEHRLVTVHTRTGSEVRPSGRKPSVAESPTSDTSTIASMAELSEMVSPLRSGSILDVRNVEQHGYTEFAVLQVCSSLVCDDLEGLVRSVSSLVGVVDFSFRINPSEATLTSSDEEDARGKGKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKB3</accession>
    <name>A0AAD8UKB3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BDZ83DRAFT_784599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000085">
        <property type="protein sequence ID" value="KAK1721339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362135.1">
        <property type="nucleotide sequence ID" value="XM_060515611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKB3"/>
    <dbReference type="GeneID" id="85399509"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00531">
        <property type="entry name" value="NTF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011944">
        <property type="entry name" value="Steroid_delta5-4_isomerase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02246">
        <property type="entry name" value="SgcJ/EcaC family oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="39"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAK1721339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="186" mass="20584" checksum="246930B83EA981B4" modified="2024-05-29" version="1">MAASCPKWSKELCYHFKPLLTPHKVSSPEAEAITSVLHAYGTALKSRNDEDVVSLYTSDGVIMPPHFTAAVGTASLRESYTRIFSSVQLVITFSIEEIIVMSPDWAFARTTAEGTKTMLATQASEEHANQELFIMKKEDGEWKIARYAFSTMKPLVQDGTNPKVFSLSSGNRHSYVKQNSTMAGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UKE0</accession>
    <name>A0AAD8UKE0_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BDZ83DRAFT_775933</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CBS 112980</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000037">
        <property type="protein sequence ID" value="KAK1725927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365982.1">
        <property type="nucleotide sequence ID" value="XM_060515457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8UKE0"/>
    <dbReference type="GeneID" id="85399355"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000061">
        <property type="entry name" value="MFS sugar transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF68">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="78"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAK1725927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="607" mass="67386" checksum="381515BFB82E27E1" modified="2024-05-29" version="1">MAEHNTAVEPNMTEKHEKREQPSDSGSRTPSSDHSSRAVDQKSKSPGGLMGFFAKMGDLPEWGFRGKPLEGKLLNWSIGFIASCGFLMFGYDQGVLSSLLTLDDFQRSITLMTPLDQSNALCWLDYPENTQRDYSQCTGDPNTQAAAVAVYQIGCFLGAFLILFYGETWGRKSSTFWGSAIMIFGTILQAGAHEYGLFSAGRIIGGVGNGMVTSTIPTWQSECARPHQRGFLITLSGALISGGIMIAYWVDYGFYFLEGTIRWRFPVAFQSFFTIIVMIGLLYLPDSPRWLAMKGRMEEARKVTSRLLGKPIDDEEVTLEVKAIQDALEVQSQGGGFQYKELLTNGPSQNLRRTLLGIAAQFFQQICGINLITYYAGFLFENSLGFGPELSRLLAALNGTEYFLASLVALPLIERTGRRKLMLFGAFGMMASMAILAGTVSTGTVADNGAPNLETRYGVTATVFLFVFNSFFAIGWLGMTWLYPAEITNLRIRIQANALSTCSNWLSNFLIVMITPPAFANLGYQTYVMFAVFNAAIIPCVYFFFPEPKGRSLEELDVIFASAHADKVNPVKRAREMRHVEGRELENELEKYFGSSEMVEDARPMMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULG3</accession>
    <name>A0AAD8ULG3_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_672883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000056">
        <property type="protein sequence ID" value="KAK1724115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060364170.1">
        <property type="nucleotide sequence ID" value="XM_060511133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULG3"/>
    <dbReference type="GeneID" id="85395032"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAK1724115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="41908" checksum="37BB934E0D2B7661" modified="2024-05-29" version="1">MEFKNLALRPAAAADAYDSDMDSEWVQTPPEDAFTDEDEIQIDSTGDLLLHVGSDASTGSTKSFRVCSNTLRRASPFWRRTLIETSSETHPAEEWCGWTPSLYACQHDKSDGLMILLNMIHARFSLVPKDPSLTEIYHTLCLASLYEMEHVFQPWIAQWYGMMKTSESTRDDRDLAMLSCIAWALGDERLFARTIIRISLTCIIDDQGHIVTPDGIRLEDYFYDSLGSPSIPETIRTLRSQLAAELPSHLNGVIDRLIDGKWLCAGISGIPVTRNKKCDYVVLGSVLAGLVYVRGTRATEVTIRADESIVDLLKSLKRVLSYVTCYEKHPECNPAEQISEAMKKTIDGMNIPLSSDCVQRMREQRQKTGWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULT7</accession>
    <name>A0AAD8ULT7_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BDZ83DRAFT_582384</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CBS 112980</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000075">
        <property type="protein sequence ID" value="KAK1722755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060362810.1">
        <property type="nucleotide sequence ID" value="XM_060505549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULT7"/>
    <dbReference type="GeneID" id="85389448"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAK1722755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <sequence length="511" mass="59024" checksum="04B017AFFF564B28" modified="2024-05-29" version="1">MGIPLQPLVDYDPLNQLGTLTTLVLASLGALGLLAWHYREDKPYAGFKLIGKERGEWSYEKARERWNNNAFELLRAGFDETHGRPFQVISPFGPLVMLPPSLCDEVRNDKRLTFTGFIDRQWLTRYPGLDILQDGLKGEIIQEAMRKNLNQELVYLTERLREETSLILREQLPSSKEWQEVRFFPVATQLAARLSAKILLGDRLCRDEEWIAVSINFTGVILRAGRALRAWPVLLRPLVHRFVPTLNYLRSQIKQARRIMEPELAARRLARDEKERPMDSLSWIDDVRRGREFDVVAGQLFLTFAAIHTTSSVVTAILYDLLAYPEYFALLREEIVKVFTEDGGWSKNSLFKLKLMDSCMKESQRLHILGPHIMNRRVEEPMTLSDGTYLPKGTLITVATHNTRDPALWGPEPDKFDGRRFLRMREEPGQENRWQFVSTSPEFLAFGHGTHACPGRFFASNEMKIVLTHLIMNYDWRIVEEKPPTSMFVSRFVPDPRTVIGCRARTPEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8ULV2</accession>
    <name>A0AAD8ULV2_GLOAC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BDZ83DRAFT_752005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi.</title>
            <authorList>
                <consortium name="DOE Joint Genome Institute"/>
                <person name="Baroncelli R."/>
                <person name="Diaz J.F."/>
                <person name="Benocci T."/>
                <person name="Peng M."/>
                <person name="Battaglia E."/>
                <person name="Haridas S."/>
                <person name="Andreopoulos W."/>
                <person name="Labutti K."/>
                <person name="Pangilinan J."/>
                <person name="Floch G.L."/>
                <person name="Makela M.R."/>
                <person name="Henrissat B."/>
                <person name="Grigoriev I.V."/>
                <person name="Crouch J.A."/>
                <person name="De Vries R.P."/>
                <person name="Sukno S.A."/>
                <person name="Thon M.R."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CBS 112980</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAHMHS010000044">
        <property type="protein sequence ID" value="KAK1725212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_060365267.1">
        <property type="nucleotide sequence ID" value="XM_060514132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD8ULV2"/>
    <dbReference type="GeneID" id="85398030"/>
    <dbReference type="Proteomes" id="UP001244207">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAK1725212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001244207"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="91063" checksum="1CCB613211034A99" modified="2024-05-29" version="1">MEDRGAQWPEHCDPLVFNTKPLNDAGYSVYSAPYDGQYRDSATHDHWPYGTLENQNNPQGFYQAINELYNVDAPQHIGWATAPSSLDHGSSDGIGQQTSTLPTRVPWPVGPVYTCPVQQNNGTRPQDNQPIERAASFHGQHFNPYGRLNHWDNSRERVSTTANSQMPSPPRSTTLSYGSSSPEDIVSPQENLLLQSGFPLSAERPQSTSISPTSRGAVPRQQPENPLLPSLQGDSRMNNNHPPFQKQARKQCLNSPTNESSSLEPPEQAGNAHRVKSLADVSSKPPLYKESAQTSMEKGSNEGGRVLEIVPRPKDSESNISNQAREPKSAGRRKRVLTDEDRRAVADTRKIGACIRCRMQRLKCEVDTENRDGPCLTCAKVDLSSSKVIHRQPCIRTKLADVVLYNVNYAGINTRPGLPANIIDIENWFDEAEHDIQLVTRGLCSVPMNIRVRKFDKDSMPVDQISYFWMNEANGEVEETKLEPYALASVSSSREQLEAYIEANAVKGWEEQAYRGDTDQLISKHYKVALEYYNDCDQHPIDRRLLLNLFKFCFAQRIMTRPSWIYNKDPKSQNCLGMSPAKDEFHPLIDRIPTPPTMTSQIRSLAHVRLVKHHEHILEDLEKLCCKKIRTSFFTVYLVTFIILHELAATTEHHKRSPFLCAAKEKEDRQESYRQYLEVAKKSANILLLHWQYYRRAPESRYATDDFLGDHVARWFWTGLEDSHEGFCRQTWRDMKKVTDDGRCHMHMSPGNPFYWISQMFDSDWSPKSIWDRVDNIVAKQEPPAEPAFKPRKATKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD8UMB2</accession>
    <name>A0AAD8UMB2_GLOAC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BDZ83DRAFT_652256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Glomerella acutata</name>
        <name type="synonym">Colletotrichum acutatum</name>
        <dbReference type="NCBI Taxonomy" id="27357"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Hypocreomycetidae</taxon>
            <taxon>Glomerellales</taxon>
            <taxon>Glomerellaceae</taxon>
            <taxon>Colletotrichum</taxon>
            <taxon>Colletotrichum acutatum species complex</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2021-12" db="EMBL/GenBank/DDBJ databases">
            <title>Comparative genomics, transcriptomics and evolutionary studies reveal genomic signatures of adaptation to plant cell wall in hemibiotrophic fungi
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